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Matters Microbial #125: Antibiotics, Streptomyces and Evolution March 15, 2026 Today Professor Paul Hoskisson, Royal Academy of Engineering Research Chair in Engineering Biology at the University of Strathclyde joins the Quality Quorum to discuss his research group's adventures studying how the bacterium Streptomyces develops, produces antibiotics, and evolves! Host: Mark O. Martin Guest: Paul Hoskisson Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode Here is a biographical sketch of the impact of Carl Woese on microbiology. Here is a fine (if dated) video describing Woese's impact and work. It's truly wonderful to hear Woese himself discuss his work and challenges. Yours truly wrote an essay on Carl Woese and undergraduate education. An article on geosmin and actinobacteria. It may smell like soil, but it has other functions, like attracting springtails! An overview of the genus Streptomyces. A video showing the beauty of the life cycle of Streptomyces and various interactions. Linear genomes in bacteria. An overview of antibiotics. Selman Waksman and early antibiotics. And a Nobel Prize! The remarkable Julian Davies and antibiotic function. Davies' concept of small molecules with functions: the parvome. A wonderful collection of articles in honor of Julian Davies. The antibiotic resistance crisis that we all face. Rapamycin and the organism that synthesizes that compound, which is an immunosuppressant helpful in organ transplantation. The concept of Biosynthetic Gene Clusters (BGC). Rich Lenski and the LTEE program to study evolution in bacteria. A wonderful video of Dr. Lenski discussing that program. The use of "evolution in the lab" with bacteria to develop new functions and activities. Possibility of "evolution proof" antibiotics. Work discussed during this podcast from Dr. Hoskisson's laboratory group exploring experimental evolution in Streptomyces. Work discussed during this podcast from Dr. Hoskisson's laboratory group investigating the evolution of natural product synthesis. Work discussed during this podcast from Dr. Hoskisson's laboratory group investigating the known and unknown genes involved with secondary metabolite production. Dr. Hoskisson's laboratory group website. Dr. Hoskisson's faculty website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
En español sería UACU, pero LUCA suena mejor. Hoy hablo del origen de la vida, de nuestra vida, y de la posibilidad de otras vidas que no conocimos con otros antepasados que no conocemos. Pero LUCA nos une con cada una de las bacterias y las arqueas en la Tierra, con los hongos, con las plantas, con cualquier ser vivo... pero no con los virus. ¿Qué nos unirá con los virus? ¿Hay vida más allá de los tres dominios de Woese?Para cualquier duda o comentario, las formas de contactar conmigo son a través de Twitter @cgdoval o por email a cgdoval@gmail.com. También esperamos tus comentarios en emilcar.fm/bacteriofagos y en nuestro grupo de Telegram https://t.me/Bacteriofagos, en el que discutimos muchos temas relacionados (o no) con la ciencia. Además, puedes mantenerte al día en cgdoval.es
David Quammen joins Nels and Vincent to talk about his new book, A Tangled Tree, including evolutionary trees, Carl Woese, Lynn Margulis, horizontal gene transfer, and much more. Hosts: Nels Elde and Vincent Racaniello Guest: David Quammen Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiEVO David's website David on TWiV 408, Boston Quammens Axel Erlandson's trees reimagined - Gilroy Gardens Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv
David Quammen's book "The Tangled Tree: A New History of Life" tells the story of evolution through the eyes of Carl Woese, a not-terribly-famous but truly ingenious revolutionary who flipped evolution on its side, literally 90 degrees. He upended Darwin's famous tree of life, showing that genes can come from almost anywhere. Woese's contributions are believed by some to be as great as Darwin's. The view of evolution that Woese brought truly was a genuine revolution. Here, David Quammen engages with Perry Marshall in a wide ranging conversation about who the real heroes in evolutionary science actually are. See acast.com/privacy for privacy and opt-out information.
Olá estudantes, sou o professor Marco Nunes e este podcast é uma revisão rápida do Nerd Cursos-Biologia sobre o sistema de classificação de Woese. Outros podcasts de revisão de classificação: https://www.nerdcursos.com.br/podcast-de-revisao-classificacao
Vincent, Michael, and Stanley review the scientific career of Carl Woese.
This is the first official podcast from thescientist, in the series; "Microbes, the little guys". In this episode we discuss the structure and information to expect from this podcast and also the taxonomic classification of life. The classification systems mentioned include the dichotomous Plant / Animal Linneas system, the 5 kingdom system by Whittaker and the widely adopted 3 Domain system by Carl Woese and George Fox. The three domain system proposed by Woese et al. had its basis in molecular biology rather than purely visual or structural characteristics and compares the sequence of the ribosome to create and identify evolutionary relationships as well as act as a bar code for the identification of organisms.