Takeda Rare Disorders Digest

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Rare Disorders Digest is a Takeda podcast series designed to inform the audience about different rare diseases, and help them understand current diagnostic and treatment modalities, and some of the challenges that clinicians and patients face today. Listeners will hear from medical experts and patient advocates as they share their insights into current care and describe their aspirations for the future. Disclosures: This podcast is made in partnership with Takeda Pharmaceuticals (Asia Pacific) Pte. Ltd., with the registered office 8 Marina Boulevard #05-02, Marina Bay Financial Centre, Tower 1, Singapore 018981. This information is available to the public for information purposes only; it should not be used for diagnosing or treating a health problem or disease. It is not intended to substitute consultation with a healthcare provider. Please consult your healthcare provider for advice. Intended for a general audience outside the US and UK.

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    • Dec 7, 2022 LATEST EPISODE
    • infrequent NEW EPISODES
    • 9m AVG DURATION
    • 11 EPISODES


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    Latest episodes from Takeda Rare Disorders Digest

    Episode 3 – Clinical experience and challenges with treating post-transplant CMV infection

    Play Episode Listen Later Dec 7, 2022 9:15


    We head to the clinic this week to hear about Prof. Joe Sasadeusz's clinical experiences with treating CMV, and the common challenges faced when managing patients with CMV infections. Learn about considerations when selecting between prophylactic and preemptive therapy for patients with CMV infections.See omnystudio.com/listener for privacy information.

    Episode 2 – Diagnosis and Treatment of Post-Transplant CMV infection

    Play Episode Listen Later Dec 7, 2022 6:16


    We chat with Prof. Joe Sasadeusz about current and upcoming approaches to diagnose and treat CMV infections. Prof. Sasadeusz also shares his thoughts on the strengths and limitations of current prophylactic and preemptive treatment strategies and gives us a glimpse into the future of CMV treatment.See omnystudio.com/listener for privacy information.

    Episode 1 - Living with a lifelong Cytomegalovirus (CMV) infection

    Play Episode Listen Later Dec 7, 2022 8:21


    CMV is a common and yet permanent infection that poses risks to people with weakened immune systems. In this episode, Prof. Joe Sasadeusz sets the scene by giving an overview of these infections alongside patient advocate, Ms Lisa Foster. CMV infections have serious consequences, especially those in high-risk groups, such as those with AIDS, and patients who are receiving immunosuppressants following a solid organ (SOT) or hematopoietic stem cell transplant (HSCT).See omnystudio.com/listener for privacy information.

    prof aids infection lifelong cmv sot hsct lisa foster cytomegalovirus cmv
    Episode 4 – Case Studies

    Play Episode Listen Later Dec 7, 2022 16:32


    In the last episode of this series on DS and LGS, Prof. Rima Nabbout shares details on several clinical cases involving DS and LGS and outlines her thought process when addressing some of the challenges associated with the diagnosis and management of these conditions in real-world settings.See omnystudio.com/listener for privacy information.

    Episode 3 – Diagnosis and treatment of LGS

    Play Episode Listen Later Dec 7, 2022 12:19


    In this episode, Prof. Rima Nabbout describes the clinical presentation, and diagnosis of LGS. She also walks us through some of the available treatment modalities and the limitations associated with treating patients with this disease.See omnystudio.com/listener for privacy information.

    Episode 2 – Diagnosis and treatment of DS

    Play Episode Listen Later Dec 7, 2022 14:14


    Prof. Rima Nabbout deep dives into the aetiology of DS, including genetic alterations such as SCN1A mutations. She also tells us about diagnosing and treating these conditions, in addition to some of the challenges she encounters in clinical practice.See omnystudio.com/listener for privacy information.

    Episode 1 – Living with Dravet Syndrome (DS) and Lennox-Gastaut Syndrome (LGS)

    Play Episode Listen Later Dec 7, 2022 13:33


    Prof. Rima Nabbout and patient advocate, Ms Lisa Foster, tell us more about DS and LGS, rare epileptic disorders that are associated with high morbidity and mortality, and the significant impact they have on patients and their families.See omnystudio.com/listener for privacy information.

    prof ds lgs dravet syndrome lisa foster lennox gastaut syndrome
    Episode 4 – Case Studies

    Play Episode Listen Later Dec 7, 2022 8:04


    In the last episode of this series on TTP, Dr Eng Soo Yap shares some of his clinical experiences with the diagnosis and management of immune-mediated and congenital forms of TTP.See omnystudio.com/listener for privacy information.

    Episode 3 – Treatment of TTP

    Play Episode Listen Later Dec 7, 2022 4:06


    Dr Eng Soo Yap helps us understand more about the role of therapeutic plasma exchange (TPE) in treating iTTP and cTTP, and some of the challenges associated with the current treatment paradigm. He also shares insights on promising therapeutics such as TAK-755 that are currently under investigation. See omnystudio.com/listener for privacy information.

    Episode 2 – Diagnosis of TTP

    Play Episode Listen Later Dec 7, 2022 3:18


    Despite extensive research in this area, TTP diagnosis continues to be a challenging affair for clinicians. Dr Eng Soo Yap helps us understand more about the current approach to diagnosis, the importance of ADAMTS13 testing, and the challenges associated with distinguishing between iTTP and cTTP. See omnystudio.com/listener for privacy information.

    Episode 1 – Living with Thrombotic Thrombocytopenic Purpura (TTP)

    Play Episode Listen Later Dec 7, 2022 10:41


    TTP is a life-threatening rare blood disorder requiring rapid diagnosis and treatment. Dr Eng Soo Yap and patient advocate, Ms Lisa Foster, help us understand more about the two main types of TTP, immune-mediated TTP (iTTP) and congenital TTP (cTTP), and the overall impact it has on the patient.See omnystudio.com/listener for privacy information.

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