Podcasts about Diagnosis

(00:00:00) 222: A Tick Just Stole Your Steak. Here's How to Get Revenge (00:00:11) Welcome to the Itchy and Bitchy Podcast (00:00:42) Doc Itchy Medical Pet Supplements (00:01:13) Introducing Alpha-Gal Syndrome (00:04:51) The Tick's Deadly Spit (00:06:32) Symptoms and Diagnosis of Alpha-Gal (00:07:47) Dietary Avoidance and Prevention (00:12:56) Tick-Borne Diseases: The Scary Truth (00:15:09) Accurate Diagnosis and Treatment Challenges (00:21:39) Tick Prevention and Safety Tips (00:23:33) Isoxazolines: A New Era in Tick Prevention Ticked Off,The Tiny Bug That Could End Your BBQ ForeverTopic: Alpha-Gal Syndrome (AGS) | Tick-Borne Food Allergy | Red Meat AllergyHost:What Is Alpha-Gal Syndrome?Alpha-gal syndrome is an IgE-mediated food allergy triggered by lone star tick bites. Symptoms  including hives, abdominal pain, and potentially life-threatening anaphylaxis, typically occur three to eight hours after eating meat, making the connection easy to miss.The Diagnosis ProblemAs of 2022, 42% of U.S. healthcare practitioners had never heard of alpha-gal syndrome, meaning patients often suffer for years without answers. What You Can DoManagement focuses on avoiding mammalian meat and products containing alpha-gal, preventing future tick bites, and referral to an allergist for severe reactions. The good news: the syndrome tends to wane over time with strict avoidance. Itchy & Bitchy is the podcast for anyone who has ever felt dismissed, misdiagnosed, or gaslit by a broken medical system.  From gut health and hormone health to autoimmune disease and chronic pain, we investigate what science actually says. We examine functional medicine, holistic health, and alternative medicine with the same skeptical If it's pseudoscience, we'll call it. If it's medical gaslighting, patient advocacy failure, or misdiagnosis we'll call that too. For chronic illness warriors, self-advocacy seekers, and wellness skeptics WE OFFER  No filters. No BS. Just the truth your doctor didn't have time to tell you.Become a supporter of this podcast: https://www.spreaker.com/podcast/itchy-bitchy-podcast--4303608/support.Itchy & Bitchy: Have you felt dismissed, misdiagnosed, or gaslit by a broken medical system.  From gut health, hormones, autoimmune disease, chronic pain, holistic health, and alternative medicine ... medical gaslighting, patient advocacy , or misdiagnosis we'll call that too.  For chronic illness warriors, self-advocacy seekers: WE OFFER  No BS 

Geoff Schwartz and Marty Hurney evaluate all 32 NFL General Managers to determine who is elite, who is up and coming and who we need to wait and see on.  Also, the guys share thoughts and prayers for Chris Johnson, who revealed he has been diagnosed with ALS after playing ten seasons in the NFL.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

I was recently diagnosed with deep vein thrombosis (DVT) or a blood clot. I was traveling for a race when symptoms presented. This is a timeline of the events that led to me getting checked and confirmed. DVT is a situation where if you don't act soon, it can get very bad. Getting checked when symptoms present is very important, and I hope to highlight that with my story.    Episode Sponsors: ProBio: probionutrition.com/endurance Code: Endurance (20% Off) LMNT: drinkLMNT.com/HPO (free sample pack with purchase) deltaG: deltagketones.com Code: BITTER20 (20% Off) True Nutrition: truenutrition.com/hpo Code: HPO (20% Off)   Podcast Details: Support HPO: zachbitter.com/hposponsors HPO Website: zachbitter.com/hpo  Zach's Coaching: zachbitter.com/coaching Zach's Journal: substack.com/@zachbitter Find Zach: zachbitter.com | IG: @zachbitter | X: @zbitter | FB: Zach Bitter | Strava: Zach Bitter   

We're back with another episode of Schauer Thoughts and this week we're taking a brief trip through the Carter Administration to explore it's ties to the agricultural industry and how that could've impacted women's health research for years to come. For legal purposes, this is all a hunch, a guess, and of course, *alleged* and I strongly recommend checking out the resources when this wraps. I hope you find this episode illuminating. Download Hily Dating App from the App Store or Google Play, or visit ⁠https://hily.go.link/jRMKW To all those dealing with chronic conditions, diseases, disabilities - I want you to know that I do care about your pain, I do care about what you have to say and your experiences. I will keep reading and keep sharing because your words and life absolutely do matter. I take you all incredibly seriously and I am so sorry for the horrific treatment you have received by the healthcare system and society at large. I am sending you absolutely nothing but the best. I will be continuing coverage of the MAHA strategy and report next week - the Trump administration's attack on the disabled community is unacceptable and we must continue to talk about it. Thank you all for listening, it means the world. Books: Sweet and Deadly: How Coca-Cola Spreads Disinformation and Makes Us Sick - Murray Carpenter Unwell Women: Misdiagnosis and Myth in a Man-Made World - Elinor Cleghorn Bleed: Destroying Myths and Misogyny in Endometriosis Care - Tracey Lindeman Expecting Inequity: How the Maternal Health Crisis Affects Even the Wealthiest Black Americans - Khiara M. Bridges Undoing Drugs: How Harm Reduction is Changing the Future of Drugs and Addiction - Maia Szalavitz All Tangled Up in Autism and Chronic Illness: A Guide to Navigating Multiple Conditions - Charli Clement Living Well With Orthostatic Intolerance: A Guide to Diagnosis and Treatment - Peter C. Rowe A Philosophy of Shame - Frederic Gros Hate: The Uses of a Powerful Emotion - Seyda Kurt Gaza: An Inquest Into Its Martyrdom - Norman G. Finkelstein  Jimmy Carter Reflecting on Jimmy Carter and his Food and Agriculture Policy Legacy https://www.constitutionpartners.com/capitol-insights/cdqbs8akjnr5i0sdpdu9u0cti5haj5 Carter's Business a Potent Factor in Rise https://www.nytimes.com/1976/05/26/archives/carters-business-a-potent-factor-in-rise.html?eafs_enabled=false Bitter Sugar for the Coca-Cola Connection? https://www.washingtonpost.com/archive/politics/1977/07/28/bitter-sugar-for-the-coca-cola-connection/c8597736-7344-4e08-bbe8-7c914f06da3b/ Cold War, Ruthless Power, and Toxic Agriculture https://www.huffpost.com/entry/cold-war-ruthless-power-a_b_5548481 Task Force on Systemic Pesticides - https://www.tfsp.info/wp-content/uploads/2014/06/WIA-PR-REL.pdf Influence of Cold War Saccharin Study and Labeling Act of 1977 https://en.wikipedia.org/wiki/Saccharin_Study_and_Labeling_Act_of_1977 Well you've just banned all women from clinical trials Literally 8 years earlier they banned another type of sugar for causing bladder tumors - https://www.ebsco.com/research-starters/politics-and-government/artificial-sweetener-cyclamate-banned-us-consumer-markets  Banned saccharin and cyclamate because it caused bladder cancer  Cyclamate Banned Us Consumer Markets https://www.ebsco.com/research-starters/politics-and-government/artificial-sweetener-cyclamate-banned-us-consumer-markets Carcinogenicity of saccharin (1987) https://pmc.ncbi.nlm.nih.gov/articles/PMC1637197/ Battle over &7.25 billion Roundup settlement takes a new turn as Supreme Court Decision looms https://www.thenewlede.org/2026/06/battle-over-7-25-bln-roundup-settlement-takes-a-new-turn-as-supreme-court-decision-looms/  Sugar industry withheld possible evidence of cancer link 50 years ago, researchers say https://www.pbs.org/newshour/science/sugar-industry-withheld-possible-evidence-of-cancer-link-50-years-ago-researchers-say  Donald Kennedy - Head of FDA in 1977 https://www.fda.gov/about-fda/fda-leadership-1907-today/donald-kennedy Stanford Biology Professor Is Named to Head FDA https://www.nytimes.com/1977/03/04/archives/stanford-biology-professor-is-named-to-head-fda.html?eafs_enabled=false Health Archives 1980 Hysterectomy Pamphlet https://bcrw.barnard.edu/archive/sexualhealth/Hysterectomy-Guide2.pdf  This is the pamphlet I was reading towards the end! Please check it out when you have the time. Initiatives & Resources: Women's Health: A Guide to Legal Resources https://onlinelaw.wcl.american.edu/blog/legal-health-resources-for-women/ Rare Diseases Clinical Research Network  https://www.rarediseasesnetwork.org/ Patient Advocate Foundation --> Launching TotalAssist (July 1,2026) https://uniting.patientadvocate.org/totalassist/ (Merger) Patient Advocate Foundation and the PAN Foundation  Patient Advocate Foundation: Co-Pay Relief - Patient Partners for Equity Program https://copays.org/patient-partners-for-equity/ If you want more information, scroll down on this page and you'll get a list of organizations for different conditions and concerns Ex: Immune Deficiency Foundation and ADAP (AIDS Drug Assistance Program) The Surprising Health Benefits Included with Your Costco membership https://www.goodhousekeeping.com/health/wellness/a70156237/costco-healthcare-benefits/ Learn more about your ad choices. Visit podcastchoices.com/adchoices

Ask Joni a question here! --------Thank you for listening! Your support of Joni and Friends helps make this show possible. Joni and Friends envisions a world where every person with a disability finds hope, dignity, and their place in the body of Christ. Become part of the global movement today at www.joniandfriends.org. Find more encouragement on Instagram, TikTok, Facebook, and YouTube.

On episode #109 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 6/4 – 6/22/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral CMV viraemia is associated with mortality among children with HIV starting antiretroviral therapy in sub-Saharan Africa (CID) Bacterial Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia(NEJM) A fatal case of Legionella micdadei prosthetic valve endocarditis diagnosed by plasma microbial cell-free DNA metagenomic sequencing (LANCET: Infectious Diseases) Legionnaires Disease Associated with a Private-Use Hot Tub in a Vacation Rental Property — New York, October 2024–April 2025 (CDC: MMWR) Notes from the Field: Case of Legionnaires Disease Associated with a Home Device Used to Mix Powdered Infant Formula — United States, 2025 (CDC:MMWR) Duration of antibiotic therapy for bacteremia in immune compromised hosts—a post hoc subgroup analysis of the BALANCErandomized clinical trial (CMI: Clinical Microbiology and Infection) FDA approves first oral carbapenem therapy for complicated urinary tract infections (FDA) Oral Tebipenem Matched IV antibiotic for complicated UTIs in Phase III Trial (MEDPAGE Today) US FDA approves GSK's oral antibiotic for drug-resistant UTIs (Reuters) Anti–Methicillin-Resistant Staphylococcus aureus (MRSA) Cephalosporins Plus Daptomycin as Initial Therapy for MRSA Bacteremia: Does a "Hit Hard and Fast" Strategy Improve Outcomes? (CID) Fungal The Last of US Season 2 (YouTube) Oral Wash PCR Improves the Diagnosis of Pneumocystis Pneumonia in Immunocompromised Patients Without HIV: A Prospective Multicenter Study (CID) Miscellaneous Foodborne Disease Outbreaks Associated with Marine Toxins — Foodborne Disease Outbreak Surveillance System, United States, 2011–2023 (CDC: MMWR) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

Dr.Lindsay Waechter-Mead highlights the value of ultrasound as pregnancy diagnosis tool, the information it can provide and keys to timing of use.

Have you ever wanted to see how AI could help with your health journey, but you had concerns, or you were too overwhelmed to know where to start? Holistic practitioner and recovery coach Lorrie Rivers joins Dr. Motley to walk through practical tips and best practices for using ChatGPT in your quest to be the CEO of your own health. Lorrie teaches how to empower yourself by approaching modern technology with the ancient arts of curiosity and dialogue to cut through overwhelm and find breakthroughs in your chronic illness journey. In this episode you'll learn: How to take advantage of ChatGPT's deep training in functional health as a support for your health journey (and what NOT to do). How to anchor and re-anchor the conversation to get the peer-to-peer information you're actually looking for, whether through a holistic, functional or TCM lens. Why most people ask AI the wrong questions — and the simple shift that gets you dramatically better answers. The difference between using AI as an "answer machine" versus a true thinking partner for your health. Whether you're a patient frustrated by long wait times and surface-level answers, or a practitioner looking to use AI as a research tool, this episode gives you a practical framework for getting real value out of artificial intelligence, without losing your own critical thinking in the process. Check out Lorrie Rivers' first episode of the Ancient Health Podcast here.  ------  Want more of The Ancient Health Podcast? Subscribe to the YouTube channel. Follow Doctor Motley Instagram Facebook Website Follow Lorrie Rivers https://lorrieriversholistic.com/ Holistic Healing with Lorrie Podcast:  https://m.youtube.com/@LorrieRiversHolistic?ra=m Get on the Waitlist For Lorrie's AI Training: AI as a Partner for Your Health Journey:  https://lorrieriversholistic.simplero.com/page/703848-waitlist-ai-heal AI for Practitioners:  https://lorrieriversholistic.simplero.com/page/703850-waitlist-ai-practitioners ------  *You can get cell support in gummy form: Mitopure now starts at $79, when you go to timeline.com/DRMOTLEY. *Join Doctor Motley's newsletter for TCM insights and regular podcast updates: https://www.doctormotley.com/ *Do you have a ton more in-depth questions for Doctor Motley? Check out his course on emotions and the body in his membership. You'll find other courses full of his TCM and frequency medicine expertise and clinical wisdom, plus bring all your questions to his weekly lives! To try risk-free for 15 days click here: https://www.doctormotley.com/15

The Diagnosis Your Doctor Is Too Afraid to Make You've been depressed, exhausted, foggy, and in pain for years. You've tried the antidepressants. You've done the workups. Everything comes back normal. But you are not normal. You are not well. And nobody can tell you why. What if it's Lyme? Dr. Terri sits down with Pamela Cipriano, DNP, APRN — a functional medicine and Lyme disease specialist who trained under one of the country's leading Lyme experts — to have the conversation most conventional doctors won't. From a teenager who spent two years in a psychiatric facility before anyone thought to test him for Lyme, to the political reality that doctors in Texas can be reported to their board just for making the diagnosis — this episode exposes why one of the most common tick-borne diseases in the country is also one of the most misdiagnosed. The symptoms of Lyme overlap almost perfectly with depression, anxiety, hormone imbalance, autoimmune disease, and neurological disorders. That's not a coincidence. It's a diagnostic crisis. If you've been chasing answers and hitting walls, this episode is for you. What you'll discover: Why the standard two-tier Lyme test misses the majority of cases and what patients should be asking for instead [12:23] How Lyme can hide in the body for decades before a stressful event triggers full-blown symptoms [06:09] The teenager misdiagnosed with a psychiatric disorder who spent two years institutionalized before anyone tested him for Lyme [20:19] Why doctors in Texas risk board complaints just for diagnosing Lyme disease and what that means for medical freedom [08:18] How Lyme symptoms overlap with hormone deficiency, creating a compounding diagnostic blind spot [31:15] Co-infections like Bartonella and Babesia: what they are, why most doctors aren't testing for them, and how they change the treatment picture [28:15] The connection between Lyme, mold toxicity, and chronic illness and why the best providers look at all of it together [33:47] How to find a provider trained to properly test and treat Lyme when only a few hundred specialists exist in the entire country [39:14] You are not crazy. You are not anxious. You may just not have the right diagnosis yet. The Dr. Terri Show is presented by EVEXIAS Health Solutions.Learn more and find a provider near you at evexias.com Connect with Dr. Terri:

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter View our full terms of use Renato Tomioka is a leading expert in reproductive medicine and gynecologic surgery whose unique skills allow him to diagnose and treat some of the most impactful yet frequently overlooked conditions affecting women's health. In this episode, Renato explores endometriosis and adenomyosis, explaining what these conditions are, why they often go undiagnosed for years despite affecting millions of women worldwide, and how advances in MRI and specialized ultrasound are transforming diagnosis beyond traditional surgical laparoscopy. He discusses the decision-making process behind hormonal therapy versus surgery, how treatment strategies change when fertility preservation is a priority, and where IVF fits into the care pathway for women with endometriosis, adenomyosis, or age-related fertility decline. Renato also examines the profound effects of female age on egg quality and quantity, including the accelerating rise in chromosomal abnormalities after age 35, highlights common mistakes in both surgical and fertility management, and shares promising developments on the horizon for treating these conditions and preserving fertility. Follow Dr. Tomioka's work: Instagram: @dr.renatotomioka; Website: Renato Tomioka, M.D., Ph.D. We discuss: 0:00:00 - Intro 0:00:11 - Endometriosis: definition, prevalence, infertility risk, and theories of disease development 0:09:03 - The biology of endometriosis: estrogen dependence, progesterone resistance, and tumor-like growth mechanisms 0:13:25 - Adenomyosis explained: how it differs from endometriosis, why it develops, and its impact on reproductive health 0:18:52 - Recognizing endometriosis and adenomyosis: the "6 Ds" of endometriosis and key differences in clinical presentation 0:22:09 - Uterine fibroids: classification, symptoms, and the importance of fibroid location for bleeding and fertility 0:24:09 - Understanding endometriosis pain: lesion-driven pain, nerve involvement, central sensitization, and the importance of early treatment 0:28:26 - Endometriosis in young women: rising prevalence, delayed diagnosis, and barriers to care 0:33:11 - Modern diagnosis of endometriosis: specialized ultrasound, MRI, and the decline of diagnostic laparoscopy 0:45:52 - Clinical case example #1: Managing endometriosis in a young woman seeking pain relief while preserving future fertility 0:54:10 - Clinical case example #2: Comparing treatment strategies for symptom control versus fertility 1:01:24 - Endometriosis and fertility: the roles of age, embryo quality, IVF, and surgery 1:11:50 - Clinical case example #3: Managing adenomyosis after failed IVF transfers to improve implantation and pregnancy outcomes 1:20:51 - The funding gap in endometriosis research: disease burden, economic impact, and growing awareness 1:22:01 - Clinical case example #4: Surgical decision-making in endometriosis—balancing pain relief, fertility preservation, and common treatment pitfalls 1:27:43 - Common misconceptions about fertility: maternal age, embryo aneuploidy, the inefficiency of human reproduction, and the limits of IVF 1:34:23 - Elective egg freezing: timing, success rates, the fertility funnel, and the tradeoffs of fertility preservation 1:45:49 - Emerging fertility technologies: mitochondrial replacement, ovarian tissue preservation, stem-cell-derived eggs, and current limitations 1:55:10 - The future of endometriosis treatment: new guidelines, biologic therapies, and unanswered questions about IVF 1:58:30 - Why earlier diagnosis matters: reducing years of suffering from endometriosis and adenomyosis Connect With Peter on Twitter, Instagram, Facebook and YouTube

If you've been told your labs are fine while your body is screaming something's wrong - this episode is your turning point.Esther Yunkin, RN, spent 17 years in emergency medicine before she walked away to help women with Hashimoto's do more than survive their diagnosis - she helps them heal it. She joins Dr. Tabatha to break down what Hashimoto's actually is, why most women go years without answers, and what you can do starting today to become the CEO of your own health.In this episode:•        The difference between hypothyroidism and Hashimoto's - and why it matters•        Why 90% of hypothyroid patients have Hashimoto's but never get tested for it•        The five categories of root causes - and which one we avoid the most•        Spiritual stress: what it is and how it drives autoimmune disease•        The seatbelt breathing trick that interrupts fight-or-flight on command•        Why vitamin D is a hormone - and what your level should actually be•        How to stop lowering the bar on what 'normal' feels likeEsther's free resource:Download "10 Thyroid Questions You Should Be Asking Your Doctor" - a printable guide to take to your next appointment.https://healthwithhashimotos.com/questions-for-your-doctor/Resources mentioned:•        Esther's podcast: healthwithhashimotos.com/podcast/•        D3K2 Lift: shop.fasttofaith.com https://shop.fasttofaith.com/product/d3-k2-lift/ Closing scripture: Isaiah 40:31"But those who hope in the Lord will renew their strength. They will soar on wings like eagles; they will run and not grow weary, they will walk and not be faint."If you've been on your own healing journey and you keep thinking, I want to help other women do this! That pull is not random. The Fast to Faith Coaching Academy was built for you. You'll learn the clinical foundations hormones, gut healing, labs, supplementation & how to coach women through the 40-Day process while building a business that honors both science & faith.  Join Today!  For just five dollars, you get five days with a certified one-on-one coach guiding you through your hormones, your gut, and your faith.Go to ftf.fasttofaith.com/empoweredbyfaithdiyReady to go deeper?The women who hear this episode and feel something shift — they belong in the Fast to Faith Sisterhood. This is where faith, functional medicine, and identity work come together with a community of women who are done managing symptoms and ready to lead from healing.If you feel called to take that even further — to guide other women through this exact transformation — the Fast to Faith Coaching Academy is where that calling becomes a career.Become a certified Fast to Faith™ coach →Weekly live mentorship with Dr. TabathaNot ready for the academy yet? Start here: 5-Day Empowered by Faith Challenge ftf.fasttofaith.com/empoweredbyfaithdiyShop Dr. Tabatha's supplement line: Use code PODCAST for 20% off your first order: shop.fasttofaith.comGet the book: Fast to Faith: A 40-Day Awakening: book.fasttofaith.com/bonus?am_id=fasttofaith5413Fast to Faith is hosted by Dr. Tabatha Barber — OB/GYN, functional medicine physician, and founder of the Fast to Faith Sisterhood and Coaching Academy.

Welcome to the Komen Health Equity Revolution series on Real Pink — where patients, advocates, researchers and community partners come together to talk honestly about what's standing in the way of breast health equity, and what we're doing to change it. June is Pride Month — a time to celebrate identity, community and the courage it takes to live authentically. Today's conversation sits right at the heart of that. Because advocating for yourself, knowing your body and refusing to be dismissed, that's not just a health message. That's a love letter to who you are. Our guest today is Shelby Smith. She was 30 years old when she noticed something felt off. No family history of breast cancer. Young, healthy, going about her life as a wife and mom to a 7-year-old daughter. But she trusted herself — and that decision changed everything. Shelby faced a 12-centimeter tumor, a bilateral mastectomy, 16 rounds of chemo and 15 rounds of radiation. She did her own research, built her own notebook, asked her own questions — and came out the other side with a message she wants every young woman to hear: Know your normal. And when something doesn't feel right, advocate for yourself. Key Takeaways: Trust your instincts when something feels off Self-advocacy can change outcomes Being informed helps patients navigate treatment Cancer can affect more than physical health Including loved ones in the journey matters Chapters 00:00 Introduction: Shelby's Breast Cancer Story 02:07 Discovering a Lump and Seeking Answers 04:37 Diagnosis, Testing, and Receiving the News 10:07 Research, Self-Advocacy, and Navigating Treatment 17:33 Identity, Family, and Talking to Her Daughter 24:46 Life After Treatment and Advice for Young Women Learn more at realpink.komen.org and komen.org Real Pink, by Susan G. Komen, shares real stories and expert insights to support people navigating breast cancer, from diagnosis through survivorship.

Next week, Matt Knaggs and Colin Goodman will attempt to set a Guinness World Record for running the 350-mile length of Ireland with MS. This week, you'll meet Matt and Colin and learn why this undertaking is so important to each of them.  We're also sharing survey results that point to gaps in how we approach MS care from the day of diagnosis. We'll tell you what it really means when you read that the prevalence of MS is increasing. It isn't bad news at all! We'll provide you with all the details you need to register for ECTRIMS Patient Community Day. And, if you can spare 20 minutes, we'll tell you how you can participate in an MS research study from the comfort of your own home. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: We're hitting the open road in Ireland with Matt Knaggs and Colin Goodman  :22 Survey points to gaps in how we approach MS care from day one  2:48 What does the increase in MS prevalence really mean?  8:48 Register for ECTRIMS 2026 Patient Community Day  12:33 An opportunity for you to participate in MS research without leaving home   14:10 Matt Knaggs and Colin Goodman talk about their attempt to set a Guinness World Record for running the length of Ireland with MS  15:56 Share this episode  32:13 Next week  32:33 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/460 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes at www.RealTalkMS.com STUDY: Understanding the Unmet Needs of People with MS at Diagnosis and Throughout Their Care Journey: Insights from a Survey-Based Study https://link.springer.com/article/10.1007/s40120-026-00942-y STUDY: Drivers of Prevalence in Major Motor Neurodegenerative Diseases: Temporal Trends in Sweden and France (2003-2022) https://www.neurology.org/doi/10.1212/WNL.0000000000218072 REGISTER: ECTRIMS 2026 Patient Community Day https://www.ectrimspatientcommunity.eu PARTICPATE IN RESEARCH: Survey: Automatic and Reflective Determinants, Fatigue, and Physical Activity for People with Multiple Sclerosis https://purdue.ca1.qualtrics.com/jfe/form/SV_douenJftXAcGxVk JOIN: The RealTalk MS Facebook Group https://facebook.com/groups/realtalkms REVIEW: Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on X, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 460 Guest: Matt Knaggs, Colin Goodman Privacy Policy

My guest Nicole Bell is the CEO of Galaxy Diagnostics and author of What Lurks in the Woods. She came to this work after her husband's Lyme disease — along with co-infections Bartonella and Babesia — was misdiagnosed as early-onset Alzheimer's. He passed away in 2022. In this episode, we talk about why the standard Lyme test misses so many people (hint: it's 30-year-old technology that relies on antibody detection from a pathogen that actively suppresses your immune system), what co-infections like Bartonella and Babesia actually do to the brain and body, and how Galaxy Diagnostics is using urine-based antigen testing and digital PCR to find what older tests can't. We also get into the myths that keep people from getting the right diagnosis — including why only 14% of Lyme patients get the classic bullseye rash, why Lyme is present in all 50 states, and why finishing a round of doxycycline doesn't mean you're in the clear. If you or someone you love is dealing with unexplained mood changes, cognitive decline, chronic fatigue, anxiety, or joint pain — this conversation is worth your full attention. For the complete show notes, links and transcripts, visit inspiredliving.show/249

"Many people have their own thing that lights them on fire, for me, it's running" say Katie O'Grady.  CF modulator drugs changes are a game changer for people living with cystic fibrosis. Katie O'Grady's story is a powerful reflection of how dramatically life with cystic fibrosis has changed in the era of CF modulators, and what becomes possible when hope replaces survival mode. A runner, speaker, and cystic fibrosis advocate in Boston, Katie redefined what it means to live with CF. Katie inspires us by talked about her shift in mindset and how it changed everything: she stopped thinking of herself as “a CF patient who runs” and began identifying as “a runner who happens to have CF.” That subtle but profound change transformed not only the way she trained, but the way she cared for herself, viewed her future, and moved through the world. For much of her life, Katie lived the reality many people with CF know too well — moving from infection to infection, never fully certain what the next year, or even the next season, might bring. At 18, she battled a devastating case of pneumonia that forced her to confront the fragility of her health. But in 2019, everything changed with the arrival of Trikafta. For the first time, Katie could imagine a future without immediately attaching fear or limitations to it. She speaks candidly about what it means to rebuild trust in your body after years of illness, and how running became far more than exercise. It became freedom, therapy, identity, and proof that her diagnosis did not get to define the boundaries of her life. Katie opens up about taking the longest break from running she'd ever experienced, wondering if she would ever return, and discovering that what she missed most wasn't competition — it was the clarity, peace, and sense of self she found while moving. To watch on YouTube: https://www.youtube.com/watch?v=zzdQraUAPfc Like, subscribe, and comment on our podcasts!Please consider making a donation: https://thebonnellfoundation.org/donate/The Bonnell Foundation website:https://thebonnellfoundation.orgEmail us at: thebonnellfoundation@gmail.com Watch our podcasts on YouTube: https://www.youtube.com/@laurabonnell1136/featuredNew: Shop our merchandise! https://thebonnellfoundation.org/product-shop/Thanks to our sponsors:Vertex: https://www.vrtx.comViatris: https://www.viatris.com/enRead us on Substack: https://substack.com/@lstb?utm_campaign=profile&utm_medium=profile-pageWatch our trailer of Embracing Egypt: https://youtu.be/RYjlB25Cr9Y

In this episode, Clarity Coach Lukas Kahler shares the gripping story of how a sudden hearing loss while traveling South America led him to paste an MRI report into ChatGPT, which ultimately revealed he had a brain tumor. He details his grueling recovery from a four-hour brain surgery that left him deaf in his right ear and permanently affects his balance. Shifting from trauma to transformation, we dive into the viral concept of life "side quests," explaining how breaking out of autopilot, practicing raw boredom, and simplifying your world is the ultimate blueprint for reclaiming true joy. -MORE FROM LUKAS:https://www.instagram.com/lukaskahler_/ (Instagram)https://lukaskahler.myflodesk.com/choose-your-quest (Free Webinar on June 30th 2026)https://www.lukaskahler.com/ (Website)-MY BOOK IS NOW OUT AND AVAILABLE RIGHT NOW:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://axelschura.com/maybe⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠-MY WEBSITE:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://axelschura.com/⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠-BOOK YOUR FREE CALL WITH US NOW AND JOIN AXEL SCHURA ACADEMY (Mention "PODCAST" when signing up to get your bonuses!):⁠⁠⁠⁠⁠⁠⁠https://calendly.com/d/cnnv-vzs-wbg/evergreen-blueprint-axel-schura-academy⁠⁠⁠⁠⁠⁠⁠-JOIN OUR NEXT FIRE WITHIN RETREAT AND MENTION "PODCAST" WHEN SIGNING UP TO GET A SPECIAL DEAL:⁠⁠⁠⁠https://calendly.com/d/cyfh-x92-gb4/axel-schura-retreat-2026⁠⁠⁠⁠-COACHING AND COMMUNITY:× 30 days FREE membership - change your life with my visualisation and meditation practices (new customers only):⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://axelschura.com/membership/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠× Free Webinar on easily scaling your Business to 10.000$ per Month:⁠⁠⁠⁠⁠⁠⁠https://event.webinarjam.com/4ywv5/register/1ypn4cz⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠-MY SUPPLEMENTS FROM WATSON NUTRITION (SAVE 5% WITH CODE "AXEL" ON EVERYTHING):D/A/CH:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://watsonnutrition.de/?ref=28⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠(Affiliate Link)⁠⁠⁠⁠⁠⁠⁠-SOCIALS:× Podcast Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://instagram.com/theaxelschurashow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠× My Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://instagram.com/axelschura⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠× You can find me and my content on all social media platforms, just follow this Linktree: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/axelschura⁠⁠⁠⁠⁠⁠⁠-00:00 Intro: How a brain tumor left me deaf and unable to walk00:55 The First Signs Something Was Wrong06:36 The MRI, Tumor Diagnosis & Facing Uncertainty12:00 What a Brain Tumor Teaches You About Life18:30 Health, Gratitude & The Wake-Up Call Most People Need26:00 Faith, Love & Getting Through Hard Times34:30 Why Relationships Matter More Than Success39:53 Side Questing: The Viral Trend Everyone Needs46:00 Digital Detox, Boredom & Escaping Phone Addiction55:47 Life Lessons, Happiness & A Side Quest Challenge

CardioNerds (Amit and Dan), Billy Joe Mullinax, and Saahil Jumkhawala discuss the long term management of pulmonary embolism with Dr. Soophia Naydenov.  The episode focuses on the approach to patients who struggle with persistent symptoms like dyspnea and fatigue even after completing the acute phase of anticoagulation. This spectrum of disease, ranging from mild post-PE impairment to chronic thromboembolic pulmonary hypertension (CTEPH), requires a structured follow-up. The discussion covers the critical importance of identifying CTEPH early, the necessary timelines for follow-up, and the appropriate objective screening tools and invasive testing to guide patient care toward full functional recovery. Audio editing by CardioNerds academy intern, Grace Qiu. Dr. Dinu Balanescu and Dr. Billy-Joe Mullinax are Co-chairs for the CardioNerds PE Series, developed in collaboration with the PERT Consortium.   Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Pulmonary Embolism PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Acronyms PE: Pulmonary Embolism PERT: Pulmonary Embolism Response Team CTEPH: Chronic Thromboembolic Pulmonary Hypertension QL: Quality of Life VTE: Venous Thromboembolism DASH: D-dimer, Age, Sex, History of non-provoked PE (a risk score) CPET: Cardiopulmonary Exercise Testing PFTs: Pulmonary Function Tests VQ Scan: Ventilation-Perfusion Scan DOACs: Direct Oral Anticoagulants TPA: Tissue Plasminogen Activator (Thrombolytics) ECMO: Extracorporeal Membrane Oxygenation Pearls: Post-PE “Syndrome” is a Spectrum: It is more accurately a spectrum of disease (sequelae of PE) rather than a single syndrome, ranging from mild fatigue/dyspnea to the most severe form, CTEPH. Structured Follow-up is Mandatory: All PE survivors need a structured follow-up, typically with checkpoints at 3, 6, 12, and 16–24 months, with the primary goal being to detect CTEPH, the deadliest, yet potentially curable, disease on the spectrum. Screening Should Be Objective and Practical: When screening for persistent symptoms, use objective assessment tools like the Post-VTE Functional Status (PVFS) scale or the Modified Medical Research Council (MMR-C) scale, as highly comprehensive but cumbersome tools (like the PE Quality of Life questionnaire) may not be practical for routine clinical use. Recurrence Risk Scores Aid in Anticoagulation Duration: Simple scores like the DASH score or the HERDO2 score (for women) can provide guidance when considering the continuation versus discontinuation of anticoagulation after the initial treatment phase. Invasive Testing for Persistent Symptoms: If a patient remains symptomatic at the 6-month mark despite normal non-invasive testing (chest X-ray, ECG, PFTs, six-minute walk, echo, VQ scan, CPET), consider invasive testing such as Right Heart Catheterization (RHC) at rest or with exercise, or an invasive CPET. Notes: Notes drafted by Saahil Jumkhawala. 1. The Spectrum of Post-PE Disease The term “post-PE syndrome” should be used with caution, as it refers to a spectrum of disease rather than a single entity. This spectrum includes symptoms (sequelae) that exist in a patient’s life following an incidental PE event that they did not have before. On one extreme is Chronic Thromboembolic Pulmonary Hypertension (CTEPH): The definition is clear, but it is the most deadly type, though thankfully rare (2% to 4%). It involves a residual clot and pulmonary hypertension identifiable at rest. In the middle is Chronic Thromboembolic Disease (CTED): Patients may have residual defects seen on a VQ or CT scan, but they do not have pulmonary hypertension. On the other side is a milder disease, which can include fatigue, dyspnea, or a patient’s perceived impairment, where the definitions of CTEPH and CTED are not met, but the patient remains symptomatic. 2. Structured Follow-up and Screening for Post-PE Symptoms Structured follow-up is key for all PE survivors, though the structure may vary based on available resources (PCP, Cardiology, Pulmonary, or multidisciplinary clinic). Recommended Timeline for Follow-up: Data from studies like ELOPE and FOCUS suggest checkpoints at 3, 6, 12, and up to 16 to 24 months. This timeline is designed to identify patients who may develop CTEPH. 88% of patients who develop CTEPH will be identified within about a year. A structured follow-up can reduce the delay in CTEPH diagnosis from 10–12 months to 4–6 months. Personal Practice Note: A quick 2–3 week/30-day check-in is recommended for severely ill patients (e.g., those who had TPA, profound shock, or ECMO support) to ensure medication compliance, manage symptoms, and identify red flags. Screening Tools (Objective Assessment): The first step is an inventory of patient symptoms, leaning toward objective rather than subjective assessment. Recommended Simple Tools: Modified Medical Research Council (MMR-C) for dyspnea evaluation. Post-VTE Functional Status (PVFS) scale. The Pulmonary Embolism Quality of Life (QL) questionnaire is comprehensive but long, making it tedious and better suited for research. Future Utility: Technology (AI/electronic tools) may assist in administering these questionnaires before the clinic visit, presenting the information as a “dashboard” for the provider. 3. Management of Persistent Symptoms and Further Testing Initial Non-Invasive Tests (Often done at 3 months): Echocardiogram VQ Scan Full PFTs Six-minute walk CPET Further Evaluation for Persistent Symptoms (e.g., at 6 months): If non-invasive tests (Chest X-ray, ECG, CPET) are normal but symptoms persist, more invasive testing should be considered as the patient has not returned to baseline. Repeat VQ scan or echocardiogram if symptoms have changed. Right Heart Catheterization (RHC) at rest or with exercise. Invasive CPET. PA gram (Pulmonary Angiogram) to assess vasculature. 4. Recurrence Risk and Anticoagulation Duration The decision to continue or discontinue anticoagulation depends on the patient’s risk factors, the situation of the PE (provoked or unprovoked), presence of active cancer, and patient preference. Recurrence Risk Scores: Simple scores are preferred for practicality. DASH Score. HERDO2 Score (particularly for women). The Vienna Score can be considered if the question is whether to restart anticoagulation after a disruption. Role of D-dimer in Abbreviation: While D-dimer can be used to guide the decision to restart anticoagulation after a planned pause (if D-dimer is high, resume), patient symptoms are preferable to guide management decisions like early abbreviation. 5. Prevention of Post-PE Syndrome Currently, there is no clear tool known to prevent the post-PE syndrome/spectrum of disease. Best Current Advice for Prevention/Recovery: Anticoagulation compliance. Pulmonary rehabilitation, which aids in faster recovery. General precautions, such as smoking cessation and body weight management. Future Research: Ongoing trials are investigating whether acute management strategies (e.g., using thrombolytics in intermediate-risk PE) can prevent long-term sequelae. (The PYTHO trial did not show a reduced rate of CTEPH in intermediate-risk PE patients who received thrombolytics). References: Khan, F., Tritschler, T., Kahn, S. R., & Rodger, M. A. “Venous Thromboembolism.” The Lancet, vol. 398, no. 10294, 2021, pp. 64-77. doi:10.1016/S0140-6736(20)32658-1. Kearon, C., & Kahn, S. R. “Long-Term Treatment of Venous Thromboembolism.” Blood, vol. 135, no. 5, 2020, pp. 317-325. doi:10.1182/blood.2019002364. Kahn, S. R., & de Wit, K. “Pulmonary Embolism.” The New England Journal of Medicine, vol. 387, no. 1, 2022, pp. 45-57. doi:10.1056/NEJMcp2116489. Di Nisio, M., van Es, N., & Büller, H. R. “Deep Vein Thrombosis and Pulmonary Embolism.” The Lancet, vol. 388, no. 10063, 2016, pp. 3060-3073. doi:10.1016/S0140-6736(16)30514-1. Chopard, R., Albertsen, I. E., & Piazza, G. “Diagnosis and Treatment of Lower Extremity Venous Thromboembolism: A Review.” JAMA, vol. 324, no. 17, 2020, pp. 1765-1776. doi:10.1001/jama.2020.17272.

Sound Healing with David Gibson How to Work with Sound to Heal Disease Peace, Activation, and the Sound-Based Path Through Anxiety, Depression, Anger, and Grief Sound Healing Center Projects and Upcoming Programs In this episode of Sound Healing, David Gibson briefly outlines the broader work of the Sound Healing Center, including Globe Institute, the Sound Healing Store, the Sound Therapy Center, the Sound Healing Research Foundation, the Medical Sound Association, and the Sound Education Association. He also announces upcoming programs, including a June 28 open house in Sausalito, in-person and online sound healing certificate programs, a recording program, a Mount Shasta retreat, and voice analysis software training. He points listeners to SoundHealingCenter.com and related project websites for classes, research, instruments, dementia protocols, treatment plans, and sound education resources. Treating Disease as Chaos and Returning the Body to Peace The main episode focuses on how sound may be used to support healing for common diseases and emotional conditions. David explains that the Medical Sound Association has developed detailed treatment plans for issues such as anxiety, depression, grief, trauma, dementia, addiction, pain, autism, cancer, anger, sleep, schizophrenia, thyroid problems, traumatic brain injury, adrenal issues, blood clots, heart conditions, digestion, suicide, end of life, ADHD, and strokes. His central idea is that disease often represents chaos or loss of coherence, while drones, vowels, crystal bowls, Tibetan bowls, tuning forks, gongs, and other stable vibrations create peace and coherence that may support healing. The Hierarchy of Vibration and the Many Layers of Peace David describes sound healing through a hierarchy of vibration: frequencies, timbre, musical intervals, musical flow, and energy. He explains that pure frequencies, low calming tones, archetypal frequencies, home notes, warm instruments, smooth musical flow, slow rhythms, breath-based chord movement, and stable energetic presence can all help create peace. He also discusses using dissonance when needed to break up stuck emotional or physical energy before returning the system to coherence. For David, peace is not only relaxation; it is the state where the immune system, organs, creativity, and deeper connection to source can function more fully. Sound, Diagnosis, and the Role of Belief A major theme is the danger of fear after a diagnosis. David shares his own experience with blood clots and says he had to stay disciplined about not collapsing into fear, because fear can weaken the immune system and interfere with healing. He contrasts discouraging responses with supportive ones, preferring people who affirm that healing is possible. He argues that doctors should not only present statistics but also guide patients toward positive intention, affirmation, and the belief that healing can happen. He repeatedly frames sound healing as a way to help the body return to peace so it can function better. Sleep, Anxiety, Panic Attacks, ADHD, Brain Injury, and Depression David gives condition-specific examples. For sleep, he recommends delta brainwave entrainment tuned to the individual and also returning to peace repeatedly throughout the day so the nervous system is not wired at bedtime. For panic attacks, he warns that many instruments can be too intense and says stillness, low calm vocal tones, loving presence, and silent chakra-toning can be more effective. For general anxiety, some instruments or sound tables may help if the person is not too fragile. For ADHD and traumatic brain injury, he emphasizes individualized brainwave entrainment. For depression, he recommends activation rather than only calming, using high frequencies, faster rhythms, activating sounds, sound tables, playlists, movement, drumming, gongs, and music that gradually builds from low mood into uplift. Anger, Boundaries, Compassion, and the Seed Beneath the Reaction David then turns to anger, saying many people become angry because they are exhausted, stressed, undernourished, sleep-deprived, or overwhelmed. He says peace can expand a person's capacity to handle life, while expression can help those who have been stuffing anger for years. He suggests intense sound, guitar, gong, or physical release when appropriate, but cautions that expression alone does not remove the seed of anger. He recommends finding the trigger, setting firm boundaries while still running love, ratcheting down exaggerated language, and using compassion as the strongest antidote. In his view, many people act harmfully because they are lost, stressed, or conditioned by society, and compassion can help prevent anger from escalating. Grief, Gratitude, and Letting the Heart Feel The final major teaching centers on grief. David says people who are grieving should not be rushed into cheerfulness; if they are crying, he encourages them to continue and let the grief move naturally. If someone is shut down and not feeling, sound and loving presence may help them reconnect with emotion. He distinguishes healthy grief from complicated grief that continues all day, every day, for years. His main antidote for grief is gratitude: recognizing the blessing of having loved someone deeply. He closes with a personal story about a woman whose friend died at the beach, a healing song played by David's roommate, and later that roommate's own death in Kauai, which David says he first felt as “okay.” The episode ends with his uplifting depression piece and a closing intention for peace and relief from depression.

In this episode of Medical Matters Podcast, the doctors discuss the strides science has made in the treatment of cancer. An overview of cancerous cells and tumors is provided, along with early treatments, of which there were few. There are four categories of cancer treatment. These methods include precision medicine, and personalized vaccines, radiotherapy, and diagnostics are also examined; the latter may further be assisted by Artificial Intelligence.Recently, a new treatment for pancreatic cancer has been found to double survival time and can be found at Health.com. Another recent potential breakthrough came from research conducted at Cornell University.Today's discussion will also demystify some of the concerns about cancer, its various forms, and the treatments now available. 

Click to Subscribe: https://bit.ly/Youtube-Subscribe-SoapDirt Young and the Restless spoilers show that Diane Jenkins (Susan Walters) plots a daring escape to free herself from the clutches of Patty's (Andrea Evans) sinister doctor. Meanwhile, Nikki Newman (Melody Thomas Scott) faces a daunting diagnosis that leaves her terrified. Victor Newman (Eric Braeden) is blindsided by a secret revelation, while Jack Abbott (Peter Bergman), in his growing desperation to find his wife, takes some risky decisions.  Y&R spoilers reveal that Victor proposes that Claire Grace Newman (Hayley Erin) spearhead a new publishing division. Concurrently, Victoria Newman (Amelia Heinle) accompanies her mother, Nikki, to the doctor where they receive a distressing diagnosis - a mass on her optic nerve could lead to blindness if left untreated. Despite the risks associated with surgery and her Multiple Sclerosis, Nikki is advised to act promptly.  The Young and the Restless spoilers indicate that while Nikki grapples with her health crisis, Diane attempts to crack Patty's doctor's phone passcode. Frustrated by her confinement, she requests to join the doctor outdoors, only to be redirected to the gym downstairs. Diane's clever manipulation of the doctor hints at her impending escape. Y&R spoilers hint that Jack dealing with Patty's erratic behavior and threats to Diane's safety. In his desperation to locate Diane, Jack instructs his son, Kyle Abbott (Michael Mealor), to tail the doctor when he leaves.  More Young and the Restless weekly spoilers confirm that Nikki, fearful of losing her sight and not wanting Victor's pity, insists that Victoria keep her diagnosis a secret. However, her secret doesn't remain hidden for long as Victor uncovers something surprising about Nikki's diagnosis.  And, Y&R weekly spoilers show that the Abbott family makes a risky move to rescue Diane, while Stephanie Simmons (Vivica A. Fox) recruits Nate Hastings (Sean Dominic) for a special project.  This episode was hosted by Belynda Gates-Turner for the #1 Soap Opera Channel, Soap Dirt. Visit our Young and the Restless section of Soap Dirt: https://soapdirt.com/category/young-and-the-restless/ Listen to our Podcasts: https://soapdirt.podbean.com/ And Check out our always up-to-date Young and the Restless Spoilers page at: https://soapdirt.com/young-and-the-restless-spoilers/ Check Out our Social Media... Twitter: https://twitter.com/SoapDirtTV Facebook: https://www.facebook.com/SoapDirt Pinterest: https://www.pinterest.com/soapdirt/ TikTok: https://www.tiktok.com/@soapdirt Instagram: https://www.instagram.com/soapdirt/

If your friend starts crying, pull up a chair and grab a tissue. Be like Romans 12 and mourn with those who mourn. -------- Thank you for listening! Your support of Joni and Friends helps make this show possible.     Joni and Friends envisions a world where every person with a disability finds hope, dignity, and their place in the body of Christ. Become part of the global movement today at www.joniandfriends.org   Find more encouragement on Instagram, TikTok, Facebook, and YouTube.

Send us Fan MailMorning Prayer (God Never Changes; Difficult Diagnosis; Rooting Out Bitterness; Clean Water; Clean Heart)Thank you for listening, our heart's prayer is for you and I to walk daily with Jesus, our joy and peaceaimingforjesus.comYouTube Channel https://www.youtube.com/@aimingforjesus5346Instagram https://www.instagram.com/aiming_for_jesus/Threads https://www.threads.com/@aiming_for_jesusX https://x.com/AimingForJesusTik Tok https://www.tiktok.com/@aiming.for.jesus

In this final meeting of The Late Diagnosis Club Season One, Dr Angela Kingdon welcomes Simon Scott, co-founder of the Autistic Culture Podcast Network, co-host of The Neurodivergent Experience, and producer of this series.Simon shares his own journey of identifying as neurodivergent, a story marked by missed signs, school struggles, identity, and years of feeling like an alien.Together, Angela and Simon reflect on Simon's work in podcasting — from co-hosting The Neurodivergent Experience to creating The Late Diagnosis Club — and how storytelling can create connection, validation, and community for neurodivergent people.In the final part of the episode, they discuss the wider Autistic Culture Podcast Network, what they are building beyond this series, and what listeners can expect next.This is a conversation about connection, self-understanding, and closing a season — while opening the door to what comes next.

This episode of the PeerDirect Medical News Podcast highlights three major developments shaping diabetes and hematologic oncology care. First, the FDA expanded approval of teplizumab for selected children and adolescents with newly diagnosed Stage 3 type 1 diabetes, making it the first therapy to modify disease progression after diagnosis by preserving beta-cell function. Additional stories review evidence supporting continuous glucose monitoring in basal insulin-treated type 2 diabetes and promising Phase III data showing talquetamab-based bispecific antibody regimens improve outcomes in relapsed or refractory multiple myeloma.

Host: Akanksha Sharma, MD Interviewee: Shannon Thomas, RN, MSN   Podcast Description: Dr Sharma has a candid, reflective conversation with Shannon Thomas, CEO of Eden Medical Center in Castro Valley, CA, and the wife of Dr. Ronnie Mimran – a beloved physician and highly skilled neurosurgeon known for his patient care and bedside manner. Dr Mimran is living with glioblastoma; he was diagnosed almost 3 years ago. We discuss her perspective as not only a caregiver but a nurse and healthcare executive, and what they have learned on this journey.

What does it actually take to diagnose REDs, and what happens after? If you've ever wondered what's going on behind the scenes when a sports medicine physician suspects REDs, this episode is your inside look. Host Heather Caplan, RDN, sits down with Dr. Rosa Pasculli, a non-operative sports medicine physician based in Atlanta, to walk through the full medical picture: how REDs gets diagnosed, what labs actually matter and why, and what treatment looks like in practice. It's a masterclass in multidisciplinary care, and a reminder of just how important it is to have a physician on your team who knows how to ask the right questions. Dr. Pasculli is a former competitive dancer turned sports medicine physician with a particular clinical interest in bone stress injuries and REDs. She is the head team physician for Emory University, overseeing 450+ varsity athletes, and serves as a consulting physician for the Atlanta Ballet, the Georgia Ballet, and the Atlanta Falcons Cheerleaders. She also sees runners, weekend warriors, and masters athletes, including, as she mentions in this episode, an 80-year-old woman doing an Ironman. 07:59- How Rosa got into sports medicine and the female athlete space 12:44- What she's seeing in the clinic: awareness of REDs and where education still falls short 14:47- REDs as a diagnosis of exclusion: what that means and why it takes a team 15:51- Lab work 101: CBC, CMP, ferritin, thyroid, and what Rosa is actually looking for 21:48- DEXA scans: who needs one and when, including the Female Athlete Triad Coalition's updated guidelines 24:22- Medical management of REDs: risk stratification, the REDs CAT2 tool, and keeping athletes in sport where possible 25:26- When it becomes dangerous: bradycardia, orthostatic changes, and the malnourished heart 28:34- Setting expectations with patients and parents around timeline and testing frequency 30:31- The Emory Women's Sports Medicine program and the cross-institutional community behind it Resources mentioned: IOC RED-S CAT2 Tool (2023)- free Excel-based risk stratification tool for clinicians Female Athlete Triad Coalition- updated DEXA scan guidelines for adolescent and adult athletes Emory Women's Sport and Wellness Conference- Saturday, August 15th, in-person and virtual; registration opening soon Connect with Dr. Pasculli through the Lane 9 Directory at lane9project.org/directory Connect + get support: Are you an athlete? Find a sports dietitian, DPT, therapist, or coach who understands athletes at lane9project.org/directory. Are you a clinician or coach? If this conversation resonated with you professionally, Lane 9 Membership was built for you. Join a community of dietitians, DPTs, psychologists, sports medicine providers, and coaches who are doing this work, and get listed in the Lane 9 Directory so athletes can find you. Future clinicians and coaches are welcome too. Follow us on Instagram and get in touch anytime!  

Traditional clinical interviews can have up to a 50% variance in ADHD diagnosis, leaving the door wide open for implicit bias. By utilizing machine learning-enabled, asynchronous assessments, Mentavi Health is wringing out biases related to race, gender, and appearance, and dropping the false-positive rate to just 12%. In this episode, host Peter Fenger speaks with Dr. Barry K. Herman, Chief Medical Officer at Mentavi Health. A Stanford-trained, board-certified adult and child psychiatrist with over 25 years of experience across managed care, pharmaceuticals, and digital health, Dr. Herman is a past president of AAPAL and a prolific researcher with over 100 scientific publications to his name. Join us as we explore Dr. Herman's non-linear journey from traditional practice to population health, the clinical validation behind the Mentavi Diagnostic Evaluation, and how decoupling diagnosis from treatment is fundamentally shifting the timeline, accuracy, and accessibility of online mental health care.   For more information about Mentavi Health, please visit: https://mentavi.com For more information about Mentavi Health's Diagnostic Evaluation, please visit: https://mentavi.com/diagnostic-evaluation/ For more information about their assessment validation study, please visit: https://mentavi.com/press-release/mentavi-health-announces-results-from-first-of-its-kind-adhd-assessment-validation-study/ Connect with Mentavi Health on social media: On Instagram: https://www.instagram.com/mentavi_health/ On Linkedin: https://www.linkedin.com/company/mentavihealth/ On YouTube: https://www.youtube.com/@mentavihealth On Facebook: https://www.facebook.com/people/Mentavi/100085316731601/ On X: https://x.com/MentaviHealth

Last 4 days before regular tickets sell out at AI Engineer World's Fair - this is the single biggest gathering of AI Engineers, Founders, Leaders, and Researchers in the world. Attendees get >$5000 worth of sponsor credits and talk tracks are looking FANTASTIC. Join us!The AI scaling debate always focuses on the question of “how do we get more GPUs?” but the better question may be: how do we make the most of ones we already have.The fact that a frontier lab like xAI could be running at sub-10% MFU (Model FLOPs Utilization) is just a hint at what the real problem may be.For context, older frontier-scale training runs were already much higher than 10%. GPT-3 was around 21% MFU. Gopher was around 32%. Megatron-Turing NLG was around 30%. PaLM reached around 46%. And our guest Anjney says best-in-class MFU today is closer to 60–70%.It's not necessarily that xAI is uniquely incompetent (it's clear they have talented folks) but rather the priorities may be flipped in the GPU arms race.While GPU access is a bottleneck, simply increasing CapEx won't automatically translate to better models as frontier AI is increasingly a systems problem: scheduling, utilization, networking, kernels, frameworks, data pipelines, parallelism, cluster reliability, and the thousand small decisions that determine whether your theoretical FLOPs become real training progress.From building Discord's developer platform and backing frontier AI companies like Anthropic, Mistral, Black Forest Labs, and Periodic Labs to now building AMP's independent compute grid, Anjney Midha has spent years close to the real bottlenecks of AI scaling. In this episode, Anjney joins swyx at Periodic Labs to unpack why the AI race is not just about buying more GPUs, why 95% utilization would have been considered an outage at Google, and why the next era of AI infrastructure has to be more aligned, more efficient, and more responsible.We go deep on AMP's vision for a compute grid that makes FLOPs flow like megawatts, the difference between full-stack AI labs and horizontal pooling, why AI data centers need community buy-in, and how compute markets could evolve into something closer to an independent system operator. Anjney also explains why DeepMind's unpublished research points to a market failure, why end-of-life prediction remains one of the most important AI applications he has thought about for fourteen years, and why “output maxing” may become a new discipline for frontier systems.We also discuss Anthropic's culture, why “luck favors the prepared mind” in coding models, how Claude cracked coding, why too much capital too early can make AI labs fragile, what Periodic Labs is trying to do with science and superconductors, why great researchers can become great CEOs, and why Silicon Valley is both deeply missionary and deeply mercenary.We discuss:* Why 95% utilization was considered an outage at Google* Why AI infrastructure waste compounds at frontier-lab scale* Why “move fast and break things” does not work for AI data centers* How data center backlash, power grids, and community incentives shape AI scaling* AMP's vision for making FLOPs flow like megawatts* Why compute needs an independent system operator* How interruptible demand and dynamic prioritization worked inside Google* Why DeepMind research hoarding creates negative externalities* AMP's 1.2GW base-load ambition and the need for 6GW of spike capacity* Why end-of-life prediction could become one of AI's most important healthcare applications* Frontier Systems, output maxing, and full-stack alignment* Why APIs and abstraction layers become lossy as organizations scale* Superconductors, standards, and the dream of lossless systems* SF Compute, open protocols, and the future of compute marketplaces* Why non-NVIDIA chips can still benefit from NVIDIA's reference architecture* Trust boundaries and why chip startups need visibility into future model architectures* Why VCs often underestimate researchers as CEOs* Scientists as star athletes of the mind* Why great CEOs need to be confrontational up and down the stack* Why leading the frontier matters more than “winning”* How Anthropic cracked coding* Why culture is fragile, not a permanent moat* Why hardship was a feature, not a bug, for Anthropic* Why Anthropic's P0 was coding from day one* Periodic Labs, physics as the constraint, and technical reality* Silicon Valley mercenaries, missionary teams, and what happens after a breakthroughAnjney Midha* LinkedIn: https://www.linkedin.com/in/anjney* X: https://x.com/AnjneyMidhaAMP PBC* Website: https://amppublic.com/* X: https://x.com/amppublicTimestamps00:00:00 Introduction00:00:09 Why AI Compute Is Being Wasted00:03:17 Responsible Infrastructure and Data Center Backlash00:06:07 AMP Grid: Making FLOPs Flow Like Megawatts00:12:41 Foundry, Frontier Labs, and Research Hoarding00:14:42 Gigawatt-Scale Compute and End-of-Life Prediction00:24:08 Frontier Systems, Output Maxing, and Alignment00:27:38 Compute Markets, SF Compute, and Non-NVIDIA Chips00:32:57 Trust Boundaries, Co-Design, and Researcher CEOs00:38:17 AI Coachella and First-Principles Thinking00:42:43 Leading vs Winning in Frontier AI00:45:54 How Anthropic Cracked Coding00:48:25 Culture, Hardship, and Anthropic's P000:54:03 Periodic Labs, Physics, and Silicon Valley Mercenaries00:56:26 Rishi Valley, Singapore, and Money as a Measure00:58:47 Closing ThoughtsTranscriptIntroduction: Anjney Midha, AMP, and Compute WasteSwyx [00:00:00]: We're in Periodic Labs with Anjney Midha, CEO, founder of AMP. Welcome.Compute Utilization: Node Allocation, MFU, and AlignmentAnjney [00:00:09]: Thanks for having me. At Google, there are two types of utilization usually, right? That you're measuring in these clusters. One is node allocation, and then the other's MFU. Node utilization is usually like what percentage of cards in the data center are just, used, and that, if it's not at, 95%-Swyx [00:00:29]: There is no excuseAnjney [00:00:29]: There's no excuse, right? I think 95% at Google, which is where my co-founder, Seb, came from, he built the Borg, PBorg/GQM scheduler at Google, and there I think 95% was considered an outage, so 96% node utilization is, should be standard. And most single-tenant clusters are not running at that. So that's one. And then MFU should be, I would say the best in class today is somewhere between 60 and 70%. I think this is a leadership question, right? Fundamentally it's an alignment question, which is are the people who are funding the cluster and then deploying the cluster actually aligned? And sometimes theoretically they are, but in practice the number of people in the chain, the supply chain between, the capital and all the way to whoever's managing the cluster and then whoever's measuring what the output is, are just so many, degrees of separation away that, the, The Have you ever heard the radian metaphor, which is at the beginning of an arc, if you have two arcs that are two lines that are just off by a few degrees, that-Swyx [00:01:33]: It spreads outAnjney [00:01:34]: It spreads out, right? Or at scale. And I think what's happening is a lot of cluster implementations and infrastructure, a lot of frontier labs and other teams, that's what's happening, is they're, they initialize the plan, which is kind of like North Star with a team that wants to do good, but then they're, required to scale so fast instead of iteratively that the wastage just compounds really fast at scale. And so I think we know the answer, which is just do iterative bring ups. If you spend time with people who've been in the semiconductor industry or the DSN industry for a long time, this is not new, and I don't think AI should be an excuse. Sure. Something What is new? Okay. We have a lot of new capabilities, but that doesn't mean just abandon common sense. Common sense should always be in fashion. ? AI scaling doesn't change the in fact, if anything, AI scaling should be putting a premium on the value of common sense and infrastructure because the margin of error now is so much lower and the costs of wastage are so much higher. And the cost of wastage, by the way, is not just economic. I'm, obviously I'm, I'm an investor, or I'm an investor by background. Over the last few years now we're running an AI infrastructure business called, AMP. And I think that it's okay to say this time is different on the capabilities front. We are genuinely getting capabilities at, of the, of a kind we haven't had before. That doesn't give you an excuse to say this time is different for everything, especially infrastructure. So look, I love the hacker mindset and the hustler mindset. Now, that's great for the startup mindset, but you remember this moment where Zuck went from saying, “Move fast, break things” to, move-Responsible Infrastructure and Data Center BacklashSwyx [00:03:10]: Fast and stable infrastructureAnjney [00:03:11]: Move fast with stable infrastructure. I think now we need to move fast with, responsible infrastructure. People are going to ask where the impact is. There was a really In our class yesterday, Scott Nolan, who's the founder of General Matter, came by at Stanford to speak about energy bottlenecks. And he had a phenomenal idea. He said, “if you look at the marginal unit economics of compute per hour,” he goes, “let's call it, $4 an hour. If you're having to bring up a new data center in a new community, why not just say we're going to charge 4.50 an hour, and that marginal impact or that marginal increase, we just literally take that and give it to the local community as cash?” I can tell you as a customer of that compute, I would love that. I'd be happy to pay an additional 50 cents per hour at scale.Swyx [00:03:57]: Wow. Yeah.Anjney [00:03:58]: Because if that means the public benefit is so clear to the communities that the data centers are coming up in, I'm going to feel like that compute is much more reliable. Up to 20% of all data centers this year in the US, my understanding is are at risk.Swyx [00:04:13]: Of community backlash?Anjney [00:04:14]: Correct. Of not getting the community support they need to get brought up.Swyx [00:04:19]: Wow. That's a huge number.Anjney [00:04:20]: Yeah. Now, we, I think we should dig into what that number is. I think it's a little bit of overstated. These things can get over-reported, but it-Swyx [00:04:27]: They don't just care about jobs. They care about all the other stuff around it, right? They care about power grid, they care about environments-Anjney [00:04:33]: Power grid, permitting, and so on. And imagine I think if you said there's a new AI deal. If we're bringing up a data center in your community, we're actually going to reduce the cost of your electricity bill. Okay, now we're talking. Right? The community's going, “Okay. Now this is a deal. I feel like a partner in this.” Right now that's not happening. There will be audits, there will be investigations, and when the, when the regulators come, I don't know when it's going to be, the folks who are moving fast and breaking things in the name of AI progress better be prepared. That's certainly not how we're procuring compute. Or we're, we're trying as much as we can to work with partners who have long-term track records. Many of whom, by the way, are not, AI providers. I think this whole idea of neoclouds being somehow this new category is a lot of marketing speak. There are really good, reliable, trusted data center providers in America who've been around 20 plus years. I love those folks. They know how to Sure. Are they sponsoring happy hours at NeurIPS? No. Are they legibly listed in Build? No. Are they hanging out in my, in, situational awareness parties? No. But they're adults. I trust them.Swyx [00:05:44]: They can run LAN. They can run power.Anjney [00:05:45]: They can run LAN, power, and shell. They have credit histories. We sit down, we have a conversations. Many of them live in Silicon Valley. They've, they've had to deal with the boom and bust cycles of the internet, and I love those folks. They are stable infrastructure partners and thinkers. And I think there's a lot of short-term thinking going on in the compute layer, and it's going to catch up to us. It's not going to be good.AMP Grid: Making FLOPs Flow Like MegawattsSwyx [00:06:07]: You talk about aligning incentives, and, I would think that aligning incentives means you have the full stack in one company, which is xAI and OpenAI, right? So you as a standalone infrastructure layer, why are you somehow more aligned to your portfolio companies than people who just own the whole thing?Anjney [00:06:28]: In systems design, right, there's, there's two regimes of, architecture, right? You have integration, and then you have pooling and utilization, right? So the Or rather, the way to increase utilization often is you can do systems integration where you collapse a lot of process into one node, or you can pull out a process from a node and share that amongst various That resource amongst several different nodes. And so we see the AMP grid, which is, the, what, the system we're building here, which is basically a compute grid. We're trying to do for compute what the electric grid-Swyx [00:07:02]: PowerAnjney [00:07:02]: Yeah, what the power grid did for electricity. It-- this is a pooling and utilization layer across clouds, And so we're actually the opposite of a full stack integration like approach.Swyx [00:07:12]: Super horizontal.Anjney [00:07:13]: Where it's much more horizontal and it's, it's multi-cloud, it's multi-silicon. The goal is to try to make FLOPs flow like megawatts, and that is very hard to do today for many reasons. There's stranded pools of compute all over the place and there's no fungibility. And so right now we do it at the level of scheduling, and we often do it at the economic layer. But as we start to announce what we're working on, it's extraordinary like how many folks are coming out of the woodworks and saying, “Hey, I'm actually working on a way to make compute fungible at this part of the stack and that part of the stack.” And as a grid, we'd like all of these folks to participate on the grid. There's, people often ask me, “Andra, are you a new cloud?” And I go, “No, actually neoclouds are suppliers.” sometimes they'll ask, “Are you a venture capital firm?” I go, “No, actually they are, they are demand like sort of off-takers of the grid.” We see ourselves as what's called an independent system operator. So if you study the history of the electric grid, once it became legible to a lot of factories and industrial sort of participants that, hey, actually it turns out pooling is a good idea. We should pool our generators instead of all having a generator running at half capacity in our backyard. There was a need for an independent entity who could coordinate all these parties. Transmission line, power generation, facilities, transmission lines, factories, and that neutral coordination mechanism is very critical. In order-- If you study like the history of grids, the most enduring ones were those that never owned their own assets. They were ones that had, or often started with long-term anchors who are uncorrelated sources of demand, a steel factory, a shoe mill or whatever in a particular town who weren't competitive, where the steel factory want to spike up at night, the shoe mill wanted to spike up during the day. So then you pool and you share, right? So each of you is guaranteed some base load, but then you kind of schedule your spikes to drive a peak utilization across the town. The gold standard, so to speak, historically, has been these utility companies like PJM Interconnect in the northeast of America, where they, over many years became this what's called an ISO, an independent system operator of the grid. So that's how we see ourselves. Economically, that's what we are. From a technical perspective, we started at the scheduling layer because Seb and Mihai, who, run engineering here, built that at-Swyx [00:09:28]: Did your schedulingAnjney [00:09:28]: They did that at Google. And, -Swyx [00:09:32]: And you have infra shops from Discord as well.Anjney [00:09:35]: I have some.Swyx [00:09:35]: I don't know, I don't know if Discord is like the primary identity, but what-whatever, I'm just kind of-Anjney [00:09:39]: No, D-Discord was-Swyx [00:09:40]: Choosing a well-known name.Anjney [00:09:42]: Well, I So I was running the developer platform there. The internal infrastructure I was not responsible for. That was actually a guy by the name of Mark Smith, who was extraordinary. And yes, Discord did pool So Discord is actually a counter example. I had the chance to learn a lot about fully, full stack infra there because-Swyx [00:09:56]: It's the same thing, yeahAnjney [00:09:57]: It's the, it's the other architecture which is, Discord built its own WebRTC vo-voice and video infra. So like Discord did not use-Swyx [00:10:08]: For the calls, yeah.Anjney [00:10:09]: Yeah, did not For communication, Discord did not use third party infra. It was all built in-house. And then the way you maximize utilization was you pool demand from the world's 200 million plus monthly active gamers, right? And so that's, that's how those stacks were constructed. Again, in systems design, the two concepts that keep coming up over and over again are abstraction and composition, right? And-Swyx [00:10:31]: Bundling and unbundlingAnjney [00:10:33]: Bundling and unbundling, abstraction, composition, like verticalization and-Swyx [00:10:36]: HorizontalAnjney [00:10:36]: Horizontalization. So in that sense, AMP is an independent system operator of the grid. We pool demand, we pool supply from a number of partners we trust At about 1.3 gigawatt scale over four years. And then we pool demand from some of the world's best, research labs and so on. We're sitting at one, periodic labs who need extraordinary long-term demand. And the idea is that, each of them is guaranteed base load on the grid, but they can spike up and down flexibly on, for compute, with much shorter timelines as needed. That was roughly the design of the program I came up with at a16z called Oxygen. The same-- That was the same design of the GQM, BorgX, Borg GQM implementation at Google that Mihai and Seb had built. Which was that how do you allow, teams inside of Google, on the internal infrastructure to be guaranteed capacity, for their base workloads? But when they need to spike up on research, how could they ensure that was sufficiently there? And of course, the big innovation that was not discovered, but kind of implemented in the space, this infra space maybe three, four years ago at Google was the idea of interruptible demand, right? Where you just queue up a bunch of jobs and through this like sort of credit system, there can be a bidding mechanism.Swyx [00:11:53]: Like priorities.Anjney [00:11:54]: It's a dynamic prioritization Basically. And jobs can get interrupted based on somebody else who's saying, “what? I have 10 tokens, 10 credits I want to spend on this job.” Another like team lead, research lead is “Genie 3 or whatever is only worth five, credits, and NanoBanana2 is worth 10 credits,” and so the NanoBanana job gets priority. That's a, that's a made up example.Swyx [00:12:15]: It's very real. Brain Marketplace was real. And, we've, we've covered this on the pod with David Luan, who was-Anjney [00:12:20]: Oh, great. OkaySwyx [00:12:20]: Was there. And the criticism is that, well, actually sometimes you need central command to go all in on a thing. And actually sometimes capitalism via credits doesn't work. Not, this is not a criticism of AMP. I'm just saying, this is a thing that has been tried, internally within Google, and it led to Google missing GPT.Foundry, Frontier Labs, and Research HoardingAnjney [00:12:41]: Like, we structured ourself essentially very similarly to Google. We are structured as a holdings company. So, Alphabet holdings is Alphabet holdings, and then they've got these subsidiaries called Google and-Swyx [00:12:51]: Other betsAnjney [00:12:52]: Other bets and so on. We've got, AMP holdings, and we've got our infrastructure business, and then we've got a capital business called Foundry that incubates new frontier AI labs or invests in them as venture capital, like Periodic. We put a few hundred million dollars into Anthropic from our fund earlier this year. So wherever we feel like teams are making progress, especially researchers and so on who've pushed the frontier inside of existing labs like DeepMind, I find, there comes a point where they feel misaligned with the dictatorship of Alphabet holdings. And at that point, sometimes the dictatorship doesn't want them anymore. And they're “Thank you. You've done your job here. You've kind of helped us through the zero to one phase, and for whatever reason, we're going to deprioritize your amazing, omni model or whatever it is, and instead we're going to prioritize coding.” And, I think that's a tragedy, but I get it. They're Sergey and team are running their own business there. But that doesn't mean we the rest of us should sit around waiting for that progress to get unlocked for the rest of the world and humanity. If you think about how much extraordinary research has happened inside of DeepMind over the last 10 years, I, Demis and Sergey and those guys did such a great job. But at the end of the day, so much of that has never seen the light of day?Swyx [00:14:00]: Or they're like papers only, but they never actually shipped it to production or-Anjney [00:14:03]: What's worse is the paper is actually not even being published anymore ‘cause there's a six-month embargo inside of DeepMind, right? We've heard about this where a paper comes out, and then I think there's a six-month embargo window where if anybody on the business team says, “This could be interesting” It's embargoed for life.Swyx [00:14:18]: Exactly. So the stuff that gets published is the stuff that's not good enough.Anjney [00:14:21]: There's an adverse selection problem, basically. Yeah. At this point-Swyx [00:14:25]: It's, it's a common complaint at NeurIPS, by the way, that's “Well, why would I look at the papers that are the trash of GDM?”Anjney [00:14:31]: Again, I think it's a tragedy. I get it. They're running their business, but the rest of the I think there's negative externalities of research being hoarded, and so that'there's a market failure. And somebody needs to unlock that research, and we can't do it on our own. We only have 1.2 gigawatts of compute. That's nothing. That's about $40 billion of cloud spend. We're going to need a lot-Gigawatt-Scale Compute and End-of-Life PredictionSwyx [00:14:51]: By the way, is that's a new number. I haven't, haven't come across that gigawatt number. That's huge.Anjney [00:14:56]: Yeah. And to be clear, we haven't secured all of it. That's how much demand we have started to secure. I think publicly we haven't actually confirmed how much we have for this year. In order-Swyx [00:15:04]: Where do you want to get to?Anjney [00:15:06]: I think the steady state would be that we have a base load pool Of 1.2 gigawatts at all times Of base load capacity. For spike capacity, right now my estimate is we need roughly six gigawatts over the next four years for all our teams to feel like they were able to keep moving the frontier, whatever they're working on, whether it's, like superconductor discovery over here. There's a new investment we're working on right now, which is in the end of life prediction space in healthcare. It's extraordinary how much you can, you can give this was actually my graduate school work. I went to grad school for bioinformatics at Stanford Med. And I know we-Swyx [00:15:40]: Econ, MCS, bio.Anjney [00:15:41]: So my-- I was this really weird cat where, I was never satisfied with my major options. So at one point I was an econ major, then I was a CS major, then I was a MCS major called mathematical computational science, and they decided they were going to end that major. So I took all that coursework, and I applied it to grad school, my graduate degree in bioinformatics, which was the master's program, and then I thought I was going to do a PhD. I never ended up doing it. I dropped out and went to work at Kleiner. But I was lucky enough to apprentice with this professor at, Stanford Med. His name is Nigam Shah, and he was working on end of life prediction. Stanford is one of the only research facilities in America that has a longitudinal patient data set that's larger at scale. I think it's at least 12 million patient lives. The only larger data set is at the VA, the Veterans Affairs, of America. And to do research, like do any deep learning and so on that data set, it was called the STRIDE data set at that time, you had to be a Stanford Med School affiliate, which is why I went and enrolled in the bioinformatics department. End of deep learning was early. Nigam Shah had the visibility-- the vision to see that, you could do end of life prediction to help palliative care. In America, the, over 30% of all Medicare, Medicaid spend, at least at that time, was spent on end of life care. And what's we grew up in Asia, so we all-- Yeah, at least I won't speak for you, but I have A very different relationship with death than I find folks who grew up in America do. In America, spiritually and culturally, especially in Western societies where Christianity, the Christian tradition sort of frames death as this terminal point, there's often a judgment day and so on. The way we view death is with a finality. In Indian culture, in Hindu culture, death is one-Swyx [00:17:35]: Also, he's Buddhist as well.Anjney [00:17:36]: You're Buddhist, yeah. So it's one, it's one step in a journey of many lives, right? And so, I grew up in this city called Chennai in the south of India, and when people die, you dance on the street. There's like a procession where your body is carried to be cremated and your family, like celebrates and there's drums and so on. It's this huge thing. And, It's because the idea is that you're going to be reincarnated. You've been liberated from the responsibilities of this life, and now you're onto your next. It's a new It's like going off to a new college or whatever, right? And so it was so alien to me when I got here as an undergrad- That the medical system works backwards from that assumption that we have to view death as this terminal thing and delay it, postpone it's a bad thing. And so at the time, clinical decision support in the United States was this very primitive field. Even to this day, physicians in the United States often will tell you when you have a terminal disease, this is your, we've diagnosed you, which is great. Our ability to diagnose you is extraordinary. You have somewhere between six months to six years to live. What do you do with that information? The error bars are so high that then you In times of uncertainty, we default to culture, and when the culture is let's-- this is a bad thing, I've got to prolong my life, then you start doing things like And just to, just sort of from a systems perspective, what's going on there is Physicians often feel like they need to provide such high error bars because there's always some uncertainty in end of life diagnosis, and if you provide the wrong Diagnosis or recommendation to your patient, you can be sued for medical malpractice. And then your license can be taken away. It can be catastrophic for your career. In contrast, if in countries where that's not the case, what you often observe is that patients, physicians are quite prescriptive with their recommendation. They say, “Hey, this is your condition. The literature says that you probably have this much time on Earth left. My expert opinion is that you are an outlier or whatever.” And they try to be more prescriptive, and that empowers a patient, right? ‘Cause then a patient can say, “I trust my doctor. They said on average, I have six months to live, but if I do these things, I may have a shot because of my particular predispositions or my genetic history or whatever.” And that empowers you to go about your life in a actually more scientific way than leaning on religion, culture, spirituality, and so on. In contrast, here, because of that medical malpractice sort of thing looming over your head, a physician never gives you a clear recommendation. So instead you say, “Okay, Doc, well, let's try it all.” And then you start a whole regime of drugs and therapies, and then you often spend weeks and weeks in the hospital, and that deteriorates your quality of life. And when that deteriorates your quality of life, you instead of spending your last few days doing the things you love with your family, you're spending it on a hospital bed. And that ends up being thirty percent of Medicare and Medicaid. So it's worse for the patients. The doctors feel terrible. The American taxpayer is paying a huge amount of money. And so this is why Nigam Shah, who was this professor at Stanford, said, “Anjney, if there's “ I kind of sat down with him. I was this young, I'd, I was twenty-one, and I was “I want to work on a big problem.” He's “The big problem is end of life care.” And so we tried to do deep learning to say, to-- So we started trying to run deep learning on these tried patient data sets to say, “Could you have an AI system make a recommendation that is orders of magnitude more precise about how much time you have left once you've been diagnosed with a terminal condition than a human?” And then if we can get that precision to be high enough, then you can empower the patient. And it turns out the tech works. Like it's-- Once you get the data set, like RL works. Honestly, even regression models work. You don't need to get that fancy. At the time, we were just trying, doing like very simple neural nets.Swyx [00:21:54]: Simple solutions, yeah.Anjney [00:21:54]: Today, what we can do with RL is extraordinary. The problem remains then and now is regulatory, because you actually can't shift the burden of the wrong clinical diagnoses from the physician to the AI system. And so at that time, I got quite disillusioned ten years ago for, twelve years ago where, ‘cause I felt I just didn't have the resources to influence regulation. Today, I'm very lucky. I'm in a different place. I've, I'm a lot older, and so I've been spending a lot of time on my next incubation, which is how can we unlock the, patient empowerment by training AI models to do end of life prediction much, with much more precision and ac-Swyx [00:22:37]: Oh, wow. You're still focused on this the whole time.Anjney [00:22:40]: The-- I haven't been able to get, this out of my mind a single day for the last fourteen years. This is the hill I want, I would like to die on. There's two, I would say. What? I actually, I'd prefer not to die.Swyx [00:22:51]: Yeah, exactly.Anjney [00:22:52]: But I think two bipartisan issues, I think two issues that should be bipartisan in America are how do we empower patients to make the right clinical decisions at the end of their life, such that we're reducing the taxpayer burden with science? It's just good old science, and AI can help here. And the second is, net positive data centers, ‘cause I think that's the biggest critical bottleneck on training and good enough AI models to help people at the end of their life. So there's sort of two sides of the, of the same scaling bottleneck curve, but those two, we formed AMP as a public benefit corporation. My wife and I, who you've met, you've met Viv. Her passion is education. Her family is a long line of educators and so on, and, of physicists. And so this class is my attempt to stop being the black sheep of the family and be a, an educator. But if I'm not educating, the thing I would be doing is working, on these two problems, whether on the political spectrum or as a researcher back at, in some lab. And my hope is if anyone's listening to this podcast, if they're passionate about either of those two topics, I'd love to hear from them. We'll, we'll we can share the contact in the show notes, but, we're looking for people to join both of those missions on the, on the political side as well as on the medical side, on the research side.Frontier Systems, Output Maxing, and AlignmentSwyx [00:24:08]: You said, this is a discipline that you want to form. You call it's called variously called Frontier System. It's variously called One Person Frontier Lab. What is the ideal name or shape of this? Like the, what is the mission?Anjney [00:24:24]: Of the class?Swyx [00:24:26]: Of the discipline that you're, exploring, right? I The class is called Frontier Systems. But like for me, maybe one phrase is you're, you're just anti-waste, right? Which is wasting GPUs, wasting in human and Medicare. But is there, is there a broader theme that I'm, that maybe you can encapsulate more succinctly?Anjney [00:24:45]: Yeah. The, from an engineering perspective, it's very simple. It's output maxing. It's the, it's the department of output maxing.Swyx [00:24:51]: Making the most of what we have.Anjney [00:24:52]: Exactly. I'm a huge believer in optimal outcomes. I think both in America and other countries, we are losing our appreciation for nuance, and this is the thing of And AI is the same case, right? Oh, the bitter lesson holds. Okay, fine. But that doesn't mean you just like throw 500 GB300, 500,000 GB300s at your suboptimal model scaling and you waste a bunch of compute. It also doesn't mean that, the most optimal is to have like 50 different architectures where there isn't enough standardization. One of the reasons Anthropic has had extraordinary sort of velocity is ‘cause they picked the transform architecture and said, “This is simple. Let's double down on it,” right? And now luckily there's enough investment going to the space that we can afford other architectures, but at the time, investment was just too fragmented into other architectures, so that arguably unlocked scaling. So I think there's a philosophy. I think we all owe it to ourselves to do output maxing with a new capability called AI on a global level. I think if I was starting a new department at Stanford, depending on how fuzzy or technical I wanted to be, I'd probably call it the Department of Alignment. Like-Swyx [00:25:59]: It's an overloaded termAnjney [00:26:01]: But it is, But alignment really Is a hard problem. And I think when you unlock it, full stack alignment is super hard in any organization and in any system. Like in a, in a venture capital firm, if you can have full stack alignment between your limited partners and your, the founders who are creating the value and ultimately the public that owns the IPO stock, that is a gift that keeps giving. And when you study the history of these systems, when they start off, they usually start out small scale where the feedback loop is actually so tight that there's alignment. And then the more you try to scale, the more division of labor happens, the more specialization happens, and at each step you add abstractions. And wherever there's an API interface, there's like loss. There's communication loss. And so I think a really cool thing would be for us to figure out is there a way for us to have our cake and eat it too as an engineering discipline? Is there a way to actually scale up and scale out Without losing any alignment, without lossy transmission?Swyx [00:27:01]: You mean standards?Anjney [00:27:02]: So standards is one way. The other way is you just have net new capabilities. So like what we're trying to do here is discover new superconductors. A room temperature superconductor would be a lossless transmission mechanism for energy. We would have flying cars. We are right within a few years of having a new room temperature superconductor. So I think those are the two. You either have to standardize On protocols or API specs that allow lossless communication, or you can come up with a whole new capability that unlocks so much abundance, the standardization doesn't matter ‘cause you just unlock net new capacity. This, the, so this is what I spend my days thinking about these days.Compute Markets, SF Compute, and Non-NVIDIA ChipsSwyx [00:27:38]: No, I think every infra person at, who wants scale and wants to output max does eventually end up thinking about this. We don't have time to go into it, but we have done an episode with SF Compute-Anjney [00:27:50]: Oh, coolSwyx [00:27:50]: That is trying to standardize The futures contract for compute. I don't, I don't know how that's going by the way, but like at some point this will be public.Anjney [00:27:57]: Oh, I think Evan is awesome and SF Compute is the kind of effort that I hope we can accelerate because what often happens is these exchanges are very hard to get, they, it's hard to bootstrap them, right? Because they often require-- There's many inefficiencies between parties. There's trust boundary inefficiencies in infrastructure because you don't trust, one part of the stack doesn't trust another part of the stack to give them visibility. There's capital markets inefficiencies, there's operational efficiencies. So if you can inject like a single shock to the system of a ton of compute demand or supply, then you can accelerate, these new flywheels. And so my hope is one day, or soon, if SF Compute needs extra like has excess capacity, they just hook it up to the grid and they get flooded with demand from us. And on the other side, if they have a ton of demand but they don't have supply, they just again hook up to the grid and it's a two-way protocol where they can just hook up to our capacity. And I don't think we're too far from that. Today our working implementation of it is mostly through a group of labs, universities, and a few sort of trusted parties who are, who all feel like they're in alignment to borrow an over sort of used word. But our hope is to just have it be an open protocol that anyone can hook up to on-Swyx [00:29:20]: Hook up for demand or hook up for supply? In primarily demand, it sounds like. Like you-Anjney [00:29:25]: No, bothSwyx [00:29:26]: You would want to offer demand.Anjney [00:29:27]: Both. Yeah. Unfortunately, what's happened in the last six weeks is, we thought we'd have a bunch of excess capacity by the end of this year. It's all gone.Swyx [00:29:37]: It's exploding.Anjney [00:29:38]: It, yeah. It's all gone. And so I have, my text messages are full of friends, we know many of these people, these are founders who've raised billions of dollars in San Francisco going, “Oh, any chance you have like 50 nodes in the next few weeks?”Swyx [00:29:51]: What is the scope for, non-Nvidia, right? You have Lisa Su coming and, Rainer Pope as well. And so There is a lot of demand for, more performance Alternative architectures and all that. At the same time, this hurts your standardization.Anjney [00:30:11]: I don't think so. So actually Rainer's a great example, right? Rainer is a CEO and founder of, MatX. I actually had him by for office hours in the class earlier today, and there was an insight he brought up that I hadn't considered before, which is when they decided to pick the standard For their data center, they picked the NVIDIA reference architecture. So the MatX chips Just plug in to any site that has an NVIDIA bring up planned. And, the-Swyx [00:30:42]: It's just software then. It's, it's not the-Anjney [00:30:44]: A-Swyx [00:30:44]: Hardware.Anjney [00:30:46]: Well, from an input and IO perspective It's the same footprint as an NVIDIA rack.Swyx [00:30:52]: That makes sense.Anjney [00:30:53]: Where they have done, innovated a bunch from what I can tell is on systems co-design. Which is where a lot of the gains are to be had. And so he picked He was “Anjney, we, there's just so much work to do when you're building a new chip company.”Swyx [00:31:08]: Can't fight every front.Anjney [00:31:08]: You just can't fight on every front. So my question to him was, “Well, you're working on this new chip. Their tape-out is next year. What, who are you going to partner with to host the chips?” And he said, “Whoever will host them. That's just not, that's not my focus.” And I said, “But how did you “ you decided back to our earlier systems design question, he decided that, he didn't want to be a full, fully integrated chip provider. The bottleneck they're focused on is the logic die, and they, he feels they can crank out a ton of performance gains through co-design there. But then that means you delegate, to our question earlier, it, you he's the data center provider is a different part of the stack, and so then he's dependent on that part of the ecosystem to host his chips to get the performance gains to the customer. So now you have another abstraction, and you might have loss. So I asked him, “How do you prevent loss?” And back to your point, he said, “I just picked the NVIDIA standard ‘cause I didn't want to Like I wanted to piggyback off of an existing protocol.” And that, what's great about NVIDIA is that reference architecture is known.Swyx [00:32:15]: Open.Anjney [00:32:15]: It's open. They've published it. So Jensen's actually enabled someone like Rainer to build a chip company like MatX, and I don't see them as competitive. The compute demand is so high. Like, I don't I think NVIDIA's not able to meet the demands of production, so we just need more chips. And I think it's very smart what MatX has done, which is say, “We're just going to we're not going to innovate on the data center design ‘cause actually, thank you, Jensen, you've done all the hard work. Where we can innovate is somewhere else.” And I think that's, that's very healthy. I think that's how we unblock new bottlenecks. And my view is these, the, chip teams like MatX, who have arrived at the insight that co-design is the way, The primary bottleneck for them is trust boundary. To do co-design well, you need visibility into the next model generation as soon as possible ‘cause it takes two years to tape out. So if by the time I bring my chip to market, your model architecture's changed, I'm host. Now, when he was inside Google, he was sitting next to the Gemini team. He was on Palm or whatever.Trust Boundaries, Co-Design, and Researcher CEOsSwyx [00:33:19]: His co-founder was the, was one, was one of the Palm guys, I think.Anjney [00:33:23]: Yes. Yes, exactly. So when you're inside the trust boundary of Google, then your systems co-design loop is super tight. When you leave as a founder, one of the biggest risks you take is now you're outside the trust boundary. And so what I love doing is helping chip teams who can help us unlock more capacity for the independent ecosystem access to trust. Because when I If I've been, involved with a lab from day one, and I was lucky enough to work with Anthropic, and then I'm on the board of Mistral and helped Black Forest Labs get started. I think at this point I'm on six or seven different teams.Swyx [00:33:57]: Only six? I feel like my mental number was going to be 13, but yeah, it's-Anjney [00:34:02]: No, I go deep with one at a time.Swyx [00:34:04]: You're founding CEO of Arena.Anjney [00:34:07]: Nah, that was an, that was an-Swyx [00:34:08]: Administrative CEOAnjney [00:34:09]: It was an administrative five-month gig where Whalen and Anastasios were graduating from their PhDs, and they didn't need a product team. So I helped recruit the head of engineering product and design. But Anastasios has always been the CEO of that company. I played a pinch-hitting I'm an intern. I was CEO intern For five months. -Swyx [00:34:33]: I interviewed him, and he's he's very well-spoken. I think he's a debate, former debate, champion. But also very quantitative and mathematical, which is-Anjney [00:34:41]: He-Swyx [00:34:41]: Such a unicorn.Anjney [00:34:43]: See, what's amazing about him? If you look at his output, he's an output maxer. By the time he was graduating from his PhD, which he only graduated last year, he had published more work with a citation count than, people twice his age. But at the same time, he'd already started a project called LLM Arena that was being used by millions of people As a side project. And time and time again, what I've realized is venture capitalists suck at seeing human beings as, dynamic agents where-Swyx [00:35:14]: They want to put you in a boxAnjney [00:35:15]: They want to put you in a box.Swyx [00:35:15]: This is your thing.Anjney [00:35:16]: So the first time I got introduced to Anastasios, somebody had told me “Oh, he's amazing, but he's a researcher.” I was “what? What do you mean he's a researcher?” That's what-Swyx [00:35:28]: Like he's not a CEO, not a founder.Anjney [00:35:29]: Not a CEO, exactly. I was “Are you crazy? Do you Have you met Dario?” Dario's a scientist. He's gone from zero to, what will soon be a trillion-dollar company in four years. Being a CEO, nominally speaking, is not that hard. Being a good CEO is hard. Being a great CEO actually requires a level of performance that scientists who have already published at the top of their field have accomplished. It is super hard to be a competitive scientist. To publish in academia over the last 20, 30 years, to make it to the top of your discipline at a place like Berkeley, you are a star athlete. Like, you are an athlete of the mind, and you perform at the highest levels. And to get there, whether you're, Anastasios or Whalen at Berkeley, or you are Robin, who-Swyx [00:36:23]: BFL, yeahAnjney [00:36:24]: With Black Forest, who created Stable Diffusion, or if you're, like Guillaume at Meta, who created Llama before he started Mistral. The amount of human leadership you have to demonstrate to get the resources, like get the trust of the organization, publish it, put it up. I would just fund researchers all day Right? If who have contributed already to the field. If they've, if they've put SOTA out there, they're, they're star athletes already. If they haven't done SOTA Look, they can still be good CEOs, but then I find the failure mode is that they just don't want to be CEOs, they primarily want to publish, and that's okay, too. One of the things we do with the AMP Grid is we donate excess compute. We have two nonprofits, like university labs. We carved out like a couple thousand H100s. But I do think there's extraordinary research being done on university campuses. My father-in-law's a physicist. He's a professor. Extraordinary work in physics, and we need that. But if you want to be a CEO, what you need to be willing To do is be super confrontational, outside of science. Like within the scientific community, some of the best researchers are very confrontational about their convictions, right? This architecture is right. To be a great CEO, you basically have to be willing to be confrontational up and down the stack.Swyx [00:37:41]: To your own team.Anjney [00:37:42]: To your own team-Swyx [00:37:43]: To customersAnjney [00:37:43]: Hiring, recruiting customers. Well, I would say, Yeah, pretty much to everyone Everybody. Of course-Swyx [00:37:50]: I see, I feel a little bit of that in my own work, but yeah, I can't imagine the stakes that Dario has had to go through. It's, it's pretty insane.Anjney [00:37:56]: No, I don't think the stakes are that different From how you're feeling it, right? Stakes are personal scaling vectors, right? The stakes that seem so low to you, like having this podcast where you can talk to somebody and just have a you're an extraordinary communicator, right? Like already in this conversation, you've pulled more out of me than most people, and I've been on 12 podcasts in the last two weeks.AI Coachella and First-Principles ThinkingSwyx [00:38:17]: I think I, we've just seen each other enough that there's some base trust.Anjney [00:38:20]: There's base trust.Swyx [00:38:20]: And I think, and I know that you, that I've done my homework and like I know that trust is a big deal for you, so.Anjney [00:38:27]: I think trust is about consistency, and you and I have seen each other In the community for years, right? Like, I remember the first time we met was at NeurIPS in New Orleans. I don't know if you remember that, luncheon.Swyx [00:38:38]: Oh my God.Anjney [00:38:39]: Reiko had set up this Reiko's amazing, and he set up this luncheon and-Swyx [00:38:43]: Yeah, I was “Who's this Discord guy?” I'm “Okay.” But-Anjney [00:38:45]: No, you weren't-Swyx [00:38:46]: You were just “You made some investments.”Anjney [00:38:47]: You were much less polite. You were “Who's this VC?” You're like-Swyx [00:38:51]: No, I Was I? Oh my God.Anjney [00:38:53]: It was-Swyx [00:38:53]: I'm so sorryAnjney [00:38:53]: It was visible on your face.Swyx [00:38:54]: I'm so sorry. But you weren't, you weren't The introduction was bad. I was I didn't know who you were.Anjney [00:39:00]: The, see, this is the thing about context, right? Like, but then I think I heard your accent. And I was “Are you-”Swyx [00:39:06]: Singapore, yeahAnjney [00:39:06]: “Are you Singaporean?” And you're “Yeah.” And I said, “I went to high school, JC, in Singapore.” And then the ice broke. But This is the there are in the scientific community, sometimes the stakes are very high for people who haven't had the emotional, what is called EQ Coaching and mentorship, right? Which is like to have scientific impact, you often need to be a extraordinary emotional, like emotionally in tune person with the folks you're trying to influence. And so what comes so naturally to you is actually a super high stakes thing to other people. And so I wouldn't assume that Dario's more stressed out than you. These things are you'd be surprised how similar and small sometimes the problems are to you That some of the world's biggest, leaders are facing. And that's what I've learned from this class. The guest speakers are Sam, Satya, Jensen.Swyx [00:40:01]: AI Coachella.Anjney [00:40:02]: Yeah. It's AI Coachella, right? So we got to get all the headliners, and they're I'm very lucky that some of these people have either mentored me over the years or I've done business with them. And when you, take the performative stuff out and any assumptions you may have about these people that you read in the press or on Twitter, We're all just humans. We're all trying to get along. And what's so special about this moment is AI is forcing, like scaling, the bitter lesson is forcing a lot of people to revise their assumptions for how the world works and go back to first principles or go and educate themselves. So the kind of people I was, I won't name who this person is, but I was at an event last week in Texas and, ran to somebody who said, “Anjney, I came across the class. What do you think about real time action prediction models?” And I was, don't know how happy it made me feel when they asked me that question. I know they've done the work. They've challenged themselves. I'm, they didn't ask me, “What do you think of world models?” They said, “What do you think of n-”Swyx [00:41:04]: Real time action predictionAnjney [00:41:05]: “action, real time action prediction models?” World models, don't get me wrong, are cool and everything, but you and I both know that is a layer of abstraction that is sometimes not usefully precise enough. Right? Ours-Swyx [00:41:16]: There's like four different kinds of world models.Anjney [00:41:17]: Yes, exactly.Swyx [00:41:18]: We've done the part with general intuition, by the way, which is very focused on, -Anjney [00:41:22]: Oh, cool. Yes. I love Pim. Pim is great. And this is what I love about people who've done that level of work. They realize they're not in competition with people who the rest of the world thinks they're in competition with.Swyx [00:41:34]: Because they're not in the category, they're in the specific thing they're trying to do.Anjney [00:41:37]: They're focused on their mission, and they have a systems understanding of the bottleneck they're trying to solve. And when somebody else says, “I'm working on real time, action prediction models too,” Pim goes, “Oh, I love that person. I want, I can learn from them.” But the minute they're “Oh, that person's a world model person,” it's “like which type of world model person?” But mostly they're just trying to figure out if it's a waste of their time, because we don't have enough time. So, Pim, for example, is super, loves this other company I work with we've talked about called Black Forest Labs. And he's mentioned to me multiple times that he's so, He thinks what Flux is doing is really cool. Andy Blattman came by and spoke in the class. And what I find over and over again is for people who do the work, who can be usefully precise enough about like what is actually going on in the world of frontier research, The sense of camaraderie is still well and alive, but it gets lost sometimes when you have to like abstract The technical complexities in, business terms And then the VCs are “How are you different from that world model?” I'm going to say Where do I even start to explain this stuff? And then the misalignment creeps in.Leading vs. Winning in Frontier AISwyx [00:42:43]: This is good. Yeah, I think, people listening get a sense of, what it is like to operate at a real level, like yourself, rather than at, the journalist level, where you have to sort of put everyone in, a rough category and create a narrative of competition, and who's winning today, who's behind.Anjney [00:42:58]: It-- this idea of winning is so Weird to me.Swyx [00:43:03]: You do want to win. You want you want competitiveness.Anjney [00:43:06]: No, I think you want to lead.Swyx [00:43:07]: You want SOTA.Anjney [00:43:07]: No, I think you want to lead. Yes, so you want to push the frontier. You want to push the SOTA. You want to do something that hasn't been done before. You want to capture value, but you don't want to capture so much value that, people think you're unaligned with your mission or trying to do what's best for the world. You want to capture enough value that you can keep innovating, right? And I think that people want to lead, they don't really This idea of winning and losing, again, I love Jensen. He's a, he's a leader. The mindset that he talked about on Dwarkesh's podcast, right? He's “I didn't wake up with a loser mindset.” I think that was awesome, right? Because he's, he's an engineer. Dwarkesh has done the work. So there's at least-- even though the, to me, it was very obvious they're talking about the same thing, they just passed each other. They just had to basically, Jensen has this, five-layer cake abstraction of how the industry works. And Dwarkesh had, I think from that podcast, had more of, a pre-training, mid-training, post-training systems loop concept.Swyx [00:44:04]: It's just a factor of who he talks to, right? Again, it's very clear.Anjney [00:44:06]: It's the systems It's the abstraction, the mental models, the It's the whole-- Dude, so much of the problem in the world is reasoning by analogy. And then the assumptions that are held invisibly.Swyx [00:44:19]: Yeah, I've, I've said, this is actually the best time in human history for first principles thinkers. Because everything you think will happen is actually now coming true.Anjney [00:44:28]: Correct. And the venture capital community is, notorious for this, where people look-- In times of uncertainty, they, cling to axioms that ended up being true from the previous era, and they kind of like proclaim them with confidence as if they're truths, but they're not. And it's very important to see the distinction between a heuristic and an axiom. An axiom can be proven-Swyx [00:44:55]: Like from internal consistency point of viewAnjney [00:44:56]: With internal consistency. A heuristic is a way you kind of a shortcut. And my God, the number of people I have had to put up with over the last few years who proclaim-- use heuristics As axioms to judge people, to judge which companies are going to succeed or the number of people who are “Oh, yeah, Anthropic, they're just training models right now,” but this one continue.Swyx [00:45:22]: Because that's a B2B SaaS?Anjney [00:45:23]: Yeah, the, like Which over the fullness of time, if you squint at it, maybe. But the way you arrive there is so important that you can-- you just, you can dismiss people. Here's what happened, right? What happened is Anthropic basically achieved takeoff in October of last year. That training run-Swyx [00:45:41]: Whatever, three seven?Anjney [00:45:42]: I forget the numbers now, but whatever that checkpoint was-Swyx [00:45:45]: We saw the cognition.Anjney [00:45:46]: Yeah. Right? You probably-- The, to those of us in the community, especially once post-training was done and it was released in December-Swyx [00:45:52]: Yeah. Can I sneak a sneaky question in there? I don't know if you have a perspective, maybe you don't, I just The number one question is how did Anthropic crack coding, right? Because Claude One, Claude Two, okay, like it was part of it, but it wasn't a big deal. And the leading hypothesis, it's a lucky dice roll that was then compounded, right? Like it was like Mildly better, but then they saw it and they were “Okay, let's really invest.”How Anthropic Cracked CodingAnjney [00:46:17]: I had this very annoying teacher. I went to this boarding school called Rishi Valley in India, which is like this, bird preserve. It's like three hundred and fifty acres of bird preserve in rural India, and there was no technology for seven years. There was this teacher, I won't name them, but they would have this-- I hated it every time he said this to me. He was “Luck fa-favors the prepared mind,” which is like a common saying, but the way he delivered it, always grated me, ‘cause he was always I was always one of those kids who got, a good grade without trying very hard. ‘Cause like high middle school is not that hard if you, if you're generally, paying attention and so on. And there was this one time where I-- But then I would get an eighty percent grade, and he would keep pushing me to say “The reason you didn't get the ninety-five plus percent is because you're not that lucky.” And I would say, “What do you mean?” ‘Cause I would think that I deserved that grade, and I would sometimes argue with him. And he'd say, “You didn't have a prepared mind. If you want to get lucky again “ There was basically one time where I got like ninety-five or ninety-six on this, on this subject, and I, now that I felt entitled. I was “Okay, I'm going to keep doing this,” and I didn't. And then he was “Luck favors a prepared mind. You got lucky last time, but you got to stay prepared.” And I didn't understand what he meant. Now, as I'm older, I'm okay, these adults actually knew a thing or two. Anthropic has been the most prepared company for four years. And so then when the right, context data comes in, the right developers start sending in, the right context diffs, Sure, you could say you got lucky, but if you ask me, they're pr-pretty damn prepared with paranoia for like four years. And you have to remember, it was so hard for them to get going early on that they had to do so much more with so much less that you just have to be prepared to be so efficient.Swyx [00:48:06]: Yes. There's numbers on their burn compared to OpenAI. I've, I've written about it, but they are so much more efficient in their, in their tech stack.Anjney [00:48:14]: It's not even It's not funny.Swyx [00:48:14]: Not even close.Anjney [00:48:15]: Yeah. But it's so clear, right? Like how to output max for the world. They have been prepared, and you could call that luck, but Luck favors the prepared mind.Culture, Hardship, and Anthropic's P0Swyx [00:48:25]: This is one of those things that I was going over some of your old lectures and, you were data, people think it's a moat and actually it's culture and actually it's team Actually. And I, it's-- there's different levels of moats, and this is the ultimate one that determines everything else. Which you can then compoundAnjney [00:48:43]: You're saying culture is the ultimate moat? Yeah. But the thing about culture is it's very fragile. So moats, I don't think they're-- there's very few moats I found that are actually moats. They're-- It's, it's a nice concept, but in reality, you have to replenish your culture. Ben Horowitz was, the speaker in CS153 on Tuesday, and I asked him this question about the culture bottleneck in teams because, there are several AI teams-Swyx [00:49:09]: His book, Hard Things About Hard ThingsAnjney [00:49:11]: Hard Thing About Hard Things. But more concretely, there are so many AI labs today that have all the cash they need, they have all the compute they need, and they're still not able to ship anything SOTA. And then you start seeing people leave and so on, and my diagnosis, it's, is it's the culture. And so I asked him, Ben, they're-- He's been one of the most aggressive investors in AI labs. He goes back to this thing which resonates in my mind a lot. It-- When I used to work at a16z, I would, book a conference room, and right outside the conference room, which is closest to the toilet ‘cause it was the fastest way for me to go use the bathroom between Zoom meetings-Swyx [00:49:45]: Oh my God, I'll put maxing my toilet optimization. Okay, never mind.Anjney [00:49:48]: It was not healthy in hindsight, but maybe this is TMI. But anyway, outside that conference on the wall was this quote that was printed that said, “Culture is not a set of beliefs, it's a set of actions.” And it's by Bushido, is this, Japanese philosopher. And if you stop taking the actions that demonstrate the mission alignment to what you've said to your team and to your-- the world matters to you, then your culture starts to fray. So it's not actually a moat, I would say. It's a very brittle, fragile thing that requires daily tending to like a garden. But if you figure out the system to keep that garden tended, which I think ultimately comes down to knowing yourself ‘cause you most naturally, if you're authentic and so on, you'll naturally make trade-offs that seem effortless to you, but that reinforce your culture. And then That becomes this very hard thing for other people to catch up to. And at Anthropic, from day one, there was this mission like-- missionary like zeal and belief that, hey, these capabilities will scale. These systems are stochastic, not deterministic. There will be error bars, and until we crack interpretability, there's risk. And at some point, people will go-- stop using Claude just for coding. They'll use it in some mission-critical context where there's-- it'll throw off a bug, and then people are going to come blame them, and they want to be on the right side of history where they said, “Yes, this is a powerful technology. We think it's going to change the world, And we want to be very measured and scientific about the fact that, ‘Hey, guys, these are stats models, statistical models.' That's how statistics works.” ultimately, when you're training neural nets, it is just a statistical system. And I think that Belief that safety is important and that it might seem toy-like in the early days, and sometimes, you could say, “Anjney, they totally over-exaggerated the risk,” like two years ago when they said, “Let's not launch Claude One,” or whatever. Well, okay, maybe in hindsight, but hindsight is twenty/twenty. And at the time, they didn't know how that model would be used, and to them it felt existential if somebody came and said, “You weren't responsible. It-- This wrote a bug.” The liability associated with that is massive. So how do you prevent against that? Well, day in, day out, you say safety. And when you start deviating from that, you have the team hold you accountable, you have the world hold you accountable, and I think that becomes a moat over time. At some point, that moat will get challenged and so on, and then it become fragile. I hope it endures because that's the beauty of having founders run the show, ‘cause they can make really hard trade-offs to do mission alignment. The hardest part is in the earliest days when you don't have a group of people who are going through difficulty, stress, crisis together, then your culture doesn't get defined sharply enough, and that's what I'm worried about right now, is there's so much money going to these labs. There's no hardship. There's no-Swyx [00:52:50]: To anyone who knowsAnjney [00:52:51]: There's no to anyone who knows. And that, in hindsight, was a feature, not a bug for Anthropic. The number of people who said no, the number of people who said, “Sorry, we're all doing investors in OpenAI,” that is competitive difference. It forces you to really understand, what is the hill you want to die on at the expense of everything else. What's the P zero? And there, P zero from day one was coding. The reason, the mechanism system there was if we crack coding, Then we will crack AGI. Our mission is AGI. We want to get there safely. If we focus on codin

Before the memory problems, confusion, and obvious dementia symptoms, many families notice something else first: money problems. Missed bill payments, unusual purchases, giving money away, falling for scams, or struggling to manage finances can sometimes be among the earliest signs of dementia. Research now shows these financial changes may appear years before a dementia diagnosis is ever made. In this episode, I explain why money management is often one of the first cognitive skills affected by dementia, what the research says about financial warning signs appearing up to six years before diagnosis, and what caregivers can do to help protect a loved one's financial security. Whether you're concerned about early signs of dementia, supporting someone with Alzheimer's disease, or already navigating the challenges of caregiving, this episode will help you understand what may be happening and what steps to take next. ⏱ CHAPTERS 0:00 - Did the money warning come before the memory problems? 2:10 - What financial warning signs actually look like 4:00 - Why managing money is the brain's first stress test 8:01 - Why these signs are so easy to miss 10:43 - Practical steps to take now #dementia #dementiacaregiver #dementiasigns #alzheimers #caregiving Get free weekly tools and tips in my newsletter, The Dementia Dose: https://tinyurl.com/dementiadose-podcast  Join the Care Collective: https://tinyurl.com/podcast-cc  --- Hi, I'm Dr. Natali Edmonds, a board-certified geropsychologist specializing in dementia care. Whether your loved one has Alzheimer's, frontotemporal, Lewy body, vascular, or mixed dementia, we believe that to create a dementia-friendly world, we must first create a caregiver-friendly world. This content is for educational purposes only and is not a substitute for professional medical advice. Always consult with a healthcare provider for medical guidance.

Dr. John Fleetham chats with Dr. Barbara Jones about her ATS guideline, "Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline."

Cara Altimus, the CEO of BD², and Emily Baxi, the Program Director of BD²'s Integrated Network, are focused on integrating research and clinical care to improve outcomes for people with bipolar disorder.  They emphasize the gaps in diagnostics and effective treatments and the need to collect comprehensive biological and clinical data to enable a precision medicine approach. Their Integrated Network is a longitudinal, large-scale study that complements their investments in new therapeutics, moving away from a trial-and-error approach to effective interventions for individuals. Cara explains, "When we think about the mission of BD², it's that we're bringing innovators and patients and the world together to drive new discovery, new understanding, and improved outcomes for people with bipolar disorder so that all people with bipolar disorder can thrive. And that thrive piece is critical to what we do. We're not just thinking about how we will change symptom outcomes, but we are thinking about how we engage across the whole life and all of the components of life, with science at the forefront of what we do." Emily elaborates, "I think it's important to acknowledge here that the tools and the technologies that we have today are quite different from even those that we had 20, 15 years ago, and they've really set the stage for how we can bring research and clinical care together. So we didn't have electronic health records in the past. We didn't have the ability to understand both from a phenotype level, meaning, can we understand the biology? Can we understand the clinical trajectory, the course of somebody's illness?" "We just didn't have the same tools to really bring clarity and understanding to that. So one of the reasons we're so excited about the Integrated Network is that it represents a framework where we're bringing those components together so that research and clinical care are really sitting side by side. So, in practice, that looks like a longitudinal cohort study." #BipolarDiscoveries #BipolarDisorder #MentalHealthResearch #PrecisionPsychiatry #LearningHealthSystem #IntegratedCare #Psychiatry #HealthcareInnovation #ClinicalResearch #DataDrivenCare #PopulationHealth bipolardiscoveries.org Listen to the podcast here

Cara Altimus, the CEO of BD², and Emily Baxi, the Program Director of BD²'s Integrated Network, are focused on integrating research and clinical care to improve outcomes for people with bipolar disorder.  They emphasize the gaps in diagnostics and effective treatments and the need to collect comprehensive biological and clinical data to enable a precision medicine approach. Their Integrated Network is a longitudinal, large-scale study that complements their investments in new therapeutics, moving away from a trial-and-error approach to effective interventions for individuals. Cara explains, "When we think about the mission of BD², it's that we're bringing innovators and patients and the world together to drive new discovery, new understanding, and improved outcomes for people with bipolar disorder so that all people with bipolar disorder can thrive. And that thrive piece is critical to what we do. We're not just thinking about how we will change symptom outcomes, but we are thinking about how we engage across the whole life and all of the components of life, with science at the forefront of what we do." Emily elaborates, "I think it's important to acknowledge here that the tools and the technologies that we have today are quite different from even those that we had 20, 15 years ago, and they've really set the stage for how we can bring research and clinical care together. So we didn't have electronic health records in the past. We didn't have the ability to understand both from a phenotype level, meaning, can we understand the biology? Can we understand the clinical trajectory, the course of somebody's illness?" "We just didn't have the same tools to really bring clarity and understanding to that. So one of the reasons we're so excited about the Integrated Network is that it represents a framework where we're bringing those components together so that research and clinical care are really sitting side by side. So, in practice, that looks like a longitudinal cohort study." #BipolarDiscoveries #BipolarDisorder #MentalHealthResearch #PrecisionPsychiatry #LearningHealthSystem #IntegratedCare #Psychiatry #HealthcareInnovation #ClinicalResearch #DataDrivenCare #PopulationHealth bipolardiscoveries.org Download the transcript here

379: Do you know there are actually low-carb potatoes?Do you avoid carbs because of gut issues like SIBO, IBS, or blood sugar spikes, and wish you could incorporate them back into your diet? Well, today I have Phoebe Lapine on the show, and she shares ways we can still enjoy carbs in the right way. It all comes down to preparation, quantity, and combining carbs with other foods, as well as experimenting to find what works for you. Phoebe is the cookbook author of SIBO Made Simple and has recently released her newest book, CARBivore. Phoebe has personally experienced SIBO, Hashimoto's, and several other health challenges I think we can all relate to. In this conversation, she shares some tips and tricks to help us expand our diets with carbs while still keeping blood sugar and IBS in check. I hope you enjoy this conversation as much as I did! Topics Discussed: → How to prepare carbs to benefit you → What to look for when buying pasta → Elimination dieting → Fiber: Helpful or harmful? → Trigger foods to avoid → Helpful foods for a SIBO diet → Low-carb potatoes → The best types of dairy to consume → Not all gluten is created equal As always, if you have any questions for the show please email us at digestthispod@gmail.com. And if you like this show, please share it, rate it, review it and subscribe to it on your favorite podcast app.  Sponsored By:  → Fatty15 | For 15% off the starter kit go to https://fatty15.com/digest → Bethany's Pantry | Go to https://bethanyspantry.com/ and use the code PODCAST10 for $10 anything! Timestamps: → 00:00:00 - Introduction → 00:00:44 - Meet Phoebe Lapine & The Carbivore Philosophy → 00:01:51 - Rapid Fire: Carbs, Gluten, Candida & Hashimoto's → 00:05:28 - Phoebe's Hashimoto's Diagnosis & Healing Journey → 00:08:24 - Gluten, Autoimmunity & Finding Root Causes → 00:09:56 - SIBO Symptoms, Testing & Treatment → 00:13:38 - Are Carbs Bad for SIBO? → 00:15:30 - Carbs, Fiber & Blood Sugar Explained → 00:18:48 - The Fiber Controversy → 00:20:14 - What Is a Low FODMAP Diet? → 00:22:04 - Foods to Avoid on Low FODMAP → 00:23:40 - Fructose, Sweeteners & Digestive Symptoms → 00:25:12 - Why Food Diversity Matters for Gut Health → 00:28:42 - Dairy, Lactose & Digestive Health → 00:31:42 - Elimination Diets vs. Low FODMAP Diets → 00:35:20 - How to Build an Effective Elimination Diet → 00:39:00 - Why Food Preparation Matters for Digestion → 00:40:04 - Sprouting, Soaking & Fermented Grains → 00:41:24 - Slow Carbs vs. Low Carbs → 00:42:12 - Why Some People Tolerate European Bread & Pasta Better → 00:46:30 - Cooking, Cooling & Resistant Starch → 00:50:30 - Low-Carb Potatoes & Selective Breeding → 00:52:34 - SIBO-Friendly Foods & Gut Healing Strategies → 00:54:32 - Phoebe's Favorite Recipes from Carbivore → 00:56:00 - Desserts, Blood Sugar & Healthy Indulgences → 00:57:36 - Hashimoto's, Perfectionism & Realistic Healing Expectations → 01:00:00 - Finding the Right Practitioner for Gut Health → 01:02:16 - Where to Find Phoebe & Her Resources → 01:03:13 - Outro  Further Listening: → Do You Need to Stop Mixing Carbs and Protein? The Shocking Digestion Secrets You've Never Heard! Connect with Phoebe Lapine:  → Instagram → Website → Get her book HERE Check Out Bethany: → Bethany's Instagram: @lilsipper → YouTube → Bethany's Website → Discounts & My Favorite Products → My Digestive Support Protein Powder → Gut Reset Book  → Get my Newsletters (Friday Finds) Learn more about your ad choices. Visit megaphone.fm/adchoices

What happens when a pediatric nurse practitioner suddenly finds herself on the other side of diagnosis? On this week's episode of Inside the Children's Hospital, Katie Taylor sits down with Laura Forcella, a developmental pediatric nurse practitioner and mom to a son with Dup15q syndrome and epilepsy. Laura shares the deeply personal journey of recognizing her son's infantile spasms, navigating a rare disease diagnosis, and balancing life as both a medical professional and a caregiver. Laura opens up about the unique challenges of being a "med mom," the emotional shift from provider to parent, and how her experiences have transformed the way she supports families in her own clinical practice. Together, Katie and Laura discuss the power of parental intuition, the importance of early intervention, building a village of support, and finding moments of joy amidst the complexities of caregiving. Whether you're a parent navigating a diagnosis, a healthcare professional supporting families, or someone looking for encouragement on a difficult journey, this conversation is filled with compassion, wisdom, and hope. In This Episode, You'll Learn: Laura's path from pediatric ICU and ER nurse to developmental pediatric nurse practitioner How she recognized the early signs of infantile spasms in her son The diagnostic journey that led to a Dup15q syndrome diagnosis What it's like to care for patients while navigating your own child's medical complexities Why videos can be critical when seeking answers for concerning symptoms The importance of trusting your instincts as a parent How early intervention services can help while waiting for specialist appointments The realities of balancing advocacy, caregiving, work, and self-care Finding community through rare disease organizations and social media How a child's diagnosis can shape and strengthen a parent's identity Resources Mentioned: Dup15q Alliance Early Intervention Programs (available in every U.S. state) Connect with Laura: Developmental Med Mom on Instagram (@developmentalmedmom) Connect with us! Instagram: @childlifeoncall + @insidethechildrenshospital Subscribe: Never miss an episode on Apple Podcasts or Spotify. Visit insidethechildrenshospital.com to search stories and episodes easily Leave a Review: It helps other families find us and access our resources   Medical information shared in this episode is not a substitute for professional medical advice. Please consult your care team for guidance specific to your child and family.   Keywords: Infantile Spasms, Dupq15, Nurse Practitioner, Developmental Pediatrics, Seizures, Child Life Specialist, Support

In this episode, I'm tackling one of the most misunderstood topics in women's health: adrenal fatigue. While the term "adrenal fatigue" isn't technically accurate, the symptoms women experience are very real. What's actually happening is something called HPA axis dysfunction, a breakdown in the communication between the brain and adrenal glands that impacts energy, hormones, metabolism, sleep, and overall health. I explain what the HPA axis is, why chronic stress changes how your body responds to cortisol, and how major life events can push your system into dysfunction even when you're doing all the "right" things. We also dive into the three major stressors that affect the body: traumas, toxins, and thoughts. If you've been feeling exhausted, overwhelmed, stuck, or like your body just isn't responding the way it used to, this episode will help you understand what's really happening beneath the surface. If you're ready to stop guessing and get personalized guidance, schedule a free Strategy Call with my team. We'll review your symptoms, discuss your health goals, and help you identify the best next steps for your body. Schedule your Strategy Call here: https://calendly.com/dr-beth-westie/program-discovery-call Download your FREE Hormone Cascade Map here: https://dr-beth-westie.mykajabi.com/hormone-cascade-map

When Claire Rumore was lifted into a hospital gurney to undergo her first biopsy, she stepped aside to use the restroom first. And while she was there, she heard a quiet internal voice ask her a question: Do you want to go back to the life you had before? Is that what you want? Without hesitation, her answer was no. What followed was one of the most unusual cancer journeys in modern medicine. Claire was 43 years old. She had stage four pancreatic cancer — a diagnosis that typically affects older men, and that her medical team never actually disclosed to her during treatment. She went through two major abdominal surgeries, dropped to 74 pounds, lost her menstrual cycle, lost her libido, and lost the person she had been. And then, slowly, over the course of eighteen months, she found her way back. Not to who she was- but to someone clearer, more embodied, and more deeply connected to her own desire than she had ever been before. In this episode, Dr. Jenni Skyler and Daniel Lebowitz sit down with Claire for a conversation about the emotional, relational, and erotic dimensions of cancer recovery that medicine almost never addresses. Claire is the founder of Cancer and Intimacy, an education platform built on a three-part framework she developed from her own experience and her work with patients, survivors, and their partners. The first lily pad is erotic grief, the deeply under addressed process of mourning what's been lost: The body you knew, the sexuality you had, the intimacy you can no longer access in the same way. Claire has written a free ebook on erotic grief and makes a compelling case that this experience is not exclusive to cancer. It's universal to anyone navigating major change. The second is libido listening. The slow, quiet, inward practice of reacquainting yourself with your own body's signals after illness or loss. Claire describes learning to feel pleasure in the sheets against her skin, in the air in the room, in the gentlest forms of touch, what she calls subtle sexuality. A term she coined to describe the low, soft, sensory orientation to desire that becomes the entry point back to conventional sexuality. Claire Rumore WebsiteSee omnystudio.com/listener for privacy information.

Every medical treatment needs to start with a diagnosis, but sometimes that diagnosis proves elusive. Sometimes it may appear that a person has one thing needing treatment, and after that treatment doesn't work, doctors have to consider other possibilities. Dr. Amit Kochhar at Pacific Neuroscience Institute sees patients with facial paralysis, which is often diagnosed as Bell's Palsy or Ramsey Hunt Syndrome—but sometimes turns out to be a cancerous tumor on a facial nerve. Doctors try to figure that out as quickly as possible, so they can remove the tumor and begin the work of restoring the patient's appearance. In today's episode, Dr. Kochhar describes these various symptoms and explains how he reaches the right diagnosis and treatment for his patients.

You've read the ADHD criteria a dozen times and still aren't sure if you actually qualify.Skye and Robbie Waterson and sit down with the DSM-5 itself and read through the inattentive criteria line by line, the same list a clinician would use for an actual diagnosis. They score themselves against each one in real time, and they don't agree on most of them.The conversation covers why the criteria were written for children and then loosely translated for adults, why "close attention to detail" means something different for someone who triple checks every payment versus someone who doesn't notice errors at all, and why your own family's version of "normal" can hide a pattern you've had your whole life. Skye also explains the difference between primarily inattentive, primarily hyperactive, and combined type, and why subclinical scores still matter even if you never meet the full six-symptom threshold.If you've ever wondered whether you "really" have ADHD or just relate to some of it, this episode shows you exactly what's being measured and why that question is harder to answer than it sounds.What We Cover:The actual nine inattentive criteria from the DSM-5, read directly from the manualWhy the same criterion can apply to one person and not the other, even with shared ADHDHow the criteria shift between children and adultsWhy family normal can mask a lifelong patternThe difference between subclinical and clinical, and why it still matters P.S. Losing work because the admin layer around your business can't keep up with you? Invisible Systems is a 90-day done-for-you sprint where I (Skye) extract the processes from your head, build the operating layer, and find the right person to run it. Six spots left at the founding price, book a call at https://www.unconventionalorganisation.com/

This episode with hip physiotherapist Mehmet Gem is a snippet taken from his Assessment of Lateral Hip Pain Practical live Q&A session. Held monthly, these sessions give Practicals members the chance to ask their clinical questions and get direct answers from expert presenters.In this episode, Mehmet discusses:Differential diagnosis in lateral hip painInterpretation of symptoms and clinical testsThe role of imaging in assessmentWhen to reassess and adapt your approach

Matilda Wray Nicholas, MD, PhD, FAAD interviewed by Alyx Cali Rosen Aigen, MD, FAAD

Have you ever been told you don't have PCOS simply because you don't have ovarian cysts, even though you're experiencing many of the classic symptoms?     On today's show, I share important news that could impact millions of women.     After decades of viewing PCOS primarily through ovarian cysts, the medical community is beginning to recognize that it's often a far more complex condition involving hormonal, metabolic, and reproductive imbalances that go well beyond the ovaries.     I break down the shift from PCOS to PMOS (Polyendocrine Metabolic Ovarian Syndrome), why this update matters, and how it may finally provide more women with the clarity and validation they've long been seeking.     I also discuss the underlying root causes behind these symptoms and why focusing on resolution at the root level, rather than simply managing symptoms, is key to achieving lasting results.     Join me on today's Cabral Concept 3784 to learn what this new understanding means for women's health and why addressing root causes is essential for long-term healing and recovery.     Enjoy the show! - - - For Everything Mentioned In Today's Show: StephenCabral.com/3784 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

What happens when the womb is treated as separate from the rest of women's health? In this episode of hol+, Dr. Taz sits down with Dr. Kemi Doll, double board-certified gynecologic oncologist, equity scientist, researcher, coach, and author of A Terrible Strength: The Hidden Crisis of the Black Womb and Your Survival Guide to Healing, for a powerful conversation about womb health, uterine cancer, fibroids, HRT, health equity, and why so many women are still being taught to normalize symptoms that deserve care.Together, they explore why womb health is not only about pregnancy, fertility, or menopause, but a lifelong part of women's physical, emotional, hormonal, and whole-body health. Dr. Doll shares how her grandmother's death in childbirth, her mother's near-death experience, and her own work as a gynecologic cancer surgeon shaped her mission to bring the uterus back into the center of women's health.Dr. Taz and Dr. Doll also discuss why uterine cancer is rising, why Black women are twice as likely to die after a uterine cancer diagnosis, and how gaps in research, screening, and diagnostic tools may leave women of color especially vulnerable. They unpack the role of ultrasound, endometrial thickness, post-menopausal bleeding, and why women need clearer conversations with their providers when something feels off.This conversation also takes a closer look at the explosion of hormone replacement therapy, or HRT, and the questions every woman with a uterus should be asking. Dr. Doll explains why estrogen without proper progesterone protection can increase uterine cancer risk, why some women may not understand the role progesterone plays, and why monitoring the uterus matters when using hormones.If you're listening to this and thinking, “I know something is off in my body, but I don't know where to start,” join the Circle here:

PCOS is often reduced to a conversation about weight, fertility, or hormones, but the reality is so much bigger.In this episode, Coach Lisa takes a deep dive into what PCOS really is, why insulin resistance plays such a powerful role, and how this condition can impact women through every stage of life. From teenagers navigating irregular cycles to women facing menopause, hysterectomy, or surgical menopause, this conversation explores the physical, emotional, and metabolic challenges that often go unseen.You'll learn why traditional diet culture approaches frequently fall short, how stress and inflammation affect your symptoms, and practical ways to support your body through nutrition, movement, and mindset. Coach Lisa also shares her own personal experience living with PCOS and surgical menopause, offering encouragement for anyone who feels frustrated, defeated, or misunderstood by their body.If you've ever felt like your body was working against you, this episode is a reminder that healing starts with understanding, nourishment, and self-compassion.

#980: Join us as we sit down with Emma Heming Willis – author, advocate, and dedicated voice for caregivers and families affected by frontotemporal dementia (FTD). A wife, mother of two, and stepmother of three, Emma is the Co-Founder and Chief Impact Officer of Make Time Wellness, a company focused on empowering women through brain health education and support. In this episode, Emma opens up about her husband Bruce Willis's FTD diagnosis and shares the realities of being a caregiver. She discusses the emotional, mental, and physical challenges that come with caregiving, breaks down common misconceptions surrounding FTD, highlights the importance of brain health awareness and early education, and reveals the lessons, tools, and support systems that have helped her navigate this journey. Emma also shares how she transformed personal adversity into purpose-driven advocacy, offering hope, guidance, and community for families facing similar challenges. This is an honest, powerful conversation about resilience, caregiving, brain health, and finding strength through connection.   For Detailed Show Notes visit TheBossticks.com   To connect with Emma Heming Willis click HERE   To connect with Lauryn Bosstick click HERE   To connect with Michael Bosstick click HERE   Read More on The Skinny Confidential HERE   Head to our ShopMy page HERE and LTK page HERE to find all of the products mentioned in each episode.   To Shop Make Time Wellness visit http://maketimewellness.com/skinny and use code skinny for 20% off for a limited time.    This episode is sponsored by PVOLVE Head to http://pvolve.com/skinny and use code SKINNY for 15% off sitewide, or on class packs at a Pvolve studio near you.   This episode is sponsored by FRE Nicotine Try FRE Nicotine Pouches today at http://FREpouch.com and use code SKINNY for 25% off for NEW customers only. WARNING: This product contains nicotine. Nicotine is an addictive chemical.   This episode is sponsored by Wayfair Patio season is here and these deals won't last! Head to http://Wayfair.com/outdoor right now to get your outdoor space ready for way less.   This episode is sponsored by Nutrafol For a limited time, Nutrafol is offering our listeners $10 off your first month's subscription and free shipping when you visit http://Nutrafol.com and enter promo code SKINNYHAIR.   This episode is sponsored by Polymarket Polymarket is now available in the U.S. App Store, with pop culture markets launching very soon. Download the app now and use code SKINNY to skip the waitlist and be first in line when those markets go live.   This episode is sponsored by Truvia If you're looking for a better way to enjoy sweetness with zero calories per serving, you really need to try the new Truvia® Allulose Plus Stevia Sweetener & Monk Fruit Sweetener—available online and nationwide at Kroger, Target and your favorite local grocery retailer.   This episode is sponsored by TruFru Find it now in the freezer aisle of your grocery store! Produced by Dear Media

Author Mary H.K. Choi is back! They discuss her new novel, Pool House, and why this mother-daughter story had to take place in Los Angeles. They also touch on her foray into hormone replacement therapy, how she dealt with her late diagnoses of AuDHD, and what it's like in New York as a creative these days. To leave a voicemail or text for a future episode, reach Doree & Elise at 781-591-0390. You can also email the podcast at forever35podcast@gmail.com.Visit forever35podcast.com for links to everything they mention on the show or visit shopmyshelf.us/forever35.Follow the podcast on Instagram (@Forever35Podcast) and sign up for the newsletter at the free tier on Patreon! Hosted on Acast. See acast.com/privacy for more information.

HOUR 1- Klein's Diagnosis, World Cup Fans and MORE full 2152 Mon, 15 Jun 2026 15:42:00 +0000 4IkLv1gGjh4luwm4SLPlfiN0Q7dyZHy8 society & culture Klein/Ally Show: The Podcast society & culture HOUR 1- Klein's Diagnosis, World Cup Fans and MORE Klein.Ally.Show on KROQ is more than just a "dynamic, irreverent morning radio show that mixes humor, pop culture, and unpredictable conversation with a heavy dose of realness." (but thanks for that quote anyway). Hosted by Klein, Ally, and a cast of weirdos (both on the team and from their audience), the show is known for its raw, offbeat style, offering a mix of sarcastic banter, candid interviews, and an unfiltered take on everything from culture to the chaos of everyday life. With a loyal, engaged fanbase and an addiction for pushing boundaries, the show delivers the perfect blend of humor and insight, all while keeping things fun, fresh, and sometimes a little bit illegal. 2024 © 2021 Audacy, Inc. Society & Culture https://player.amperwavepodcasting.com?feed-

Nonspecific low back pain is a leading cause of disability, with most cases lacking a clear anatomic cause. This episode reviews  risk factors, diagnosis, and current  evidence-based treatments for acute and chronic low back pain. JAMA Deputy Editor Mary M. McDermott, MD, interviews author James McAuley, PhD, of the University of New South Wales. Related Content: Low Back Pain What Is Low Back Pain?

Last week we ran into a no-start condition that you don't see every day... but twice in the same week. Listen to find out the cause and diagnostics you can perform to pinpoint this issue. Vehicles mentioned, 2015 Chevrolet Silverado, 2002 Honda Odyssey, & 2007 Ford Mustang. Website- https://autodiagpodcast.com/Facebook Group- https://www.facebook.com/groups/223994012068320/YouTube- https://www.youtube.com/@automotivediagnosticpodcas8832Email- STmobilediag@gmail.comPlease make sure to check out our sponsors!SJ Auto Solutions- https://sjautosolutions.com/Automotive Seminars- https://automotiveseminars.com/L1 Automotive Training- https://www.l1training.com/Autorescue tools- https://autorescuetools.com/   

In today's episode of Psych Talk I chat with Dr. Jeremy Thompson, a medical practitioner and former President of the Australian Society for Psychological Medicine. Dr. Thompson talks about his book Understand Your True Identity: Discover the Real You and Enjoy Healthier Relationships and discusses different types of identities, including the "mixed-bag" identity and how it develops. We discuss the "diagnosis generation" and why more people are turning diagnostic labels into personal identities more frequently. We discuss Positive-Centered Psychology and how it helps with the identity crisis many people are facing. Dr. Thompson also discusses steps we can take to ensure that we or those we care about do not turn diagnostic labels into our personal identities.Information shared by guests on Psych Talk are reflective of their own values, perspectives, and life experiences. Psych Talk values platforming various perspectives and experiences even if those views are not necessarily reflective of Psych Talk's values and perspectives. Connect with Dr. Thompson:Website: www.drjeremythompson.comBook: Understand Your True IdentityYouTube: Dr. Jeremy ThompsonIG: @drjeremythompsonConnect with Me:Follow me on IG ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@jessicaleighphd⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow the podcast on IG ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@psych.talk.podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow me on TikTok ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@jessicaleighphd⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Follow me on ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow me on Threads ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@jessicaleighphd⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Welcome to Group Therapy Podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Ways to Work With Me:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Mind Over Matter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LGBTQ+ Affirming Masterclass⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Be a guest on my podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Resources:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Anti-Racism Resources⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LGBTQ+ Affirming Resources⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Helping Professional's Guide to Boundary Setting⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Intro/Outro Music⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Life of Riley⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ by Kevin MacLeod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Music License⁠⁠⁠⁠⁠⁠⁠⁠