Podcasts about Infection

Invasion of an organism's body tissues by disease-causing agents

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Best podcasts about Infection

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Latest podcast episodes about Infection

Tick Boot Camp
Episode 602: How Bartonella Hijacks the Brain's Immune System: Linking Infection and Neurodegeneration – Dr. Janice Bush

Tick Boot Camp

Play Episode Listen Later Dec 9, 2025 19:35


Overview This special episode of the Tick Boot Camp Podcast was recorded live at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and PCOM Symposium in collaboration with Pathobiome Perspectives. Hosted by Ali Moresco in partnership with Nikki Schultek, Executive Director of AlzPI, this series expands the Tick Boot Camp mission of exploring infection-associated chronic illness (IACI)—including Lyme and other tick-borne infections—to the global Alzheimer's and neuroimmunology research community. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen partnered with Ali and Nikki to showcase scientists exploring the microbial and immune mechanisms behind neurodegeneration. This episode features Dr. Janice Bush, a PhD candidate at North Carolina State University's College of Veterinary Medicine, whose research under world-renowned Bartonella expert Dr. Edward Breitschwerdt investigates how Bartonella bacteria alter gene expression in the brain's immune cells. Guest Janice Bush, DVM, PhD Candidate College of Veterinary Medicine, North Carolina State University (NCSU) Dr. Janice Bush began her career in veterinary medicine, where she observed a striking overlap between illnesses in pets and their human owners—particularly those linked to vector-borne infections like Bartonella. Now completing her PhD under Dr. Edward Breitschwerdt, she focuses on Bartonella henselae, the bacterium behind Cat Scratch Disease, and its ability to infect human microglial cells—the brain's resident immune defenders. Her presentation, “Bartonella-Infected Human Microglial Cells: Transcriptional Changes Associated with Chronic Neurologic Disorders,” revealed how this stealth pathogen triggers widespread gene dysregulation linked to Alzheimer's disease, psychiatric symptoms, and neurodegenerative processes. Key Discussion Points Dr. Bush explains how Bartonella infection reprograms human microglia, the brain's innate immune cells, leading to hundreds of genes being upregulated or suppressed—affecting energy metabolism, mitochondrial function, cell signaling, and immune communication. These cellular changes mirror those observed in chronic neurological and psychiatric disorders, providing a potential mechanistic link between infection and long-term neurodegeneration. She describes Bartonella's sophisticated immune evasion strategy, including its ability to hijack cellular machinery and increase production of interleukin-10 (IL-10)—an anti-inflammatory cytokine that suppresses immune response, allowing the bacteria to persist undetected. This mechanism may explain why patients experience cyclic flares and remissions, and why Bartonella can linger silently for years. Dr. Bush's findings suggest that even short-term infections can produce measurable transcriptional changes in brain immune cells within 48 hours. If such infections persist for months or years, they may set the stage for neurodegenerative disease, particularly when combined with other pathogens or environmental factors. “If one intracellular pathogen can cause this many changes in two days, imagine what happens over months or years. Bartonella may be the spark that primes the brain for neurodegeneration.” — Dr. Janice Bush Why It Matters Dr. Bush's research offers a groundbreaking look at how a common, underrecognized infection may drive neuroinflammation and neurodegeneration. Her work bridges veterinary medicine, infectious disease, and neurology—revealing how pathogens once dismissed as minor or self-limiting may alter the brain's immune landscape. By demonstrating that Bartonella can infect and manipulate microglial cells, she provides critical biological evidence linking vector-borne disease and cognitive decline, paving the way for future diagnostic and therapeutic innovation. About the Event This interview was recorded at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and Philadelphia College of Osteopathic Medicine (PCOM) Symposium, held October 3, 2025, at Ohio University in Dublin, Ohio. The event gathered more than 20 leading researchers exploring how microbes, the microbiome, and immune dysregulation contribute to Alzheimer's, dementia, and infection-associated chronic illness (IACI). The Tick Boot Camp Podcast, in partnership with Ali Moresco and Nikki Schultek, documented these conversations to connect the chronic Lyme, infectious disease, and Alzheimer's research communities. This episode is part of Tick Boot Camp's AlzPI collaboration series. Learn More Learn more about the Alzheimer's Pathobiome Initiative (AlzPI) Listen to Tick Boot Camp Podcast episodes, including Episode 406: Pathobiome – An Interview with Nikki Schultek and Episode 101: The Young Gun – An Interview with Alex (Ali) Moresco discussed in this interview.

The School of Doza Podcast
What Really Happens When You Catch the Flu?

The School of Doza Podcast

Play Episode Listen Later Dec 8, 2025 30:07


Learn exactly how the flu makes you sick and how to interrupt each phase of infection. Discover the science-backed supplements that act as "fire extinguishers" for inflammation, why vitamin D and NAC are essential during flu season, and how to support your immune system before, during, and after viral infections to recover faster and stay healthier year-round. 5 KEY TAKEAWAYS The flu is a viral infection that never truly leaves your body – it can lay dormant and flare up during times of stress, making prevention and immune support crucial year-round, not just during illness. Vitamin D and NAC are your immune system's "fire extinguishers" – both reduce pro-inflammatory cytokines (like TNF-α and IL-6) that cause severe lung inflammation during flu infections, helping you recover faster and experience less severe symptoms. NAC does triple duty during flu season – it thins mucus for easier breathing, reduces inflammation in the lungs, and boosts glutathione production (your body's master antioxidant) to fight viral infections more effectively. Most people are deficient in the nutrients needed to fight flu – vitamin D deficiency affects most of the population, and low levels of glutathione, zinc, and selenium make you more vulnerable to severe viral infections and slower recovery. Viral infections deplete your adrenal glands – the constant stress response during and after flu infection tanks your HRV and DHEAS levels, requiring adrenal support to fully recover and prevent long-term fatigue or autoimmune-like symptoms. FEATURED PRODUCT The D - provides 5,000 IU of vitamin D3, which acts as a "fire extinguisher" for inflammatory cytokines released during viral infections, reducing lung inflammation and supporting your body's natural immune response.  Find it here: https://mswnutrition.com/products/the-d TIMESTAMPS 00:00 – START 02:45 – Why the flu is a viral infection that never leaves your body 05:30 – How respiratory viruses spread and enter your system 08:15 – NAC: The game-changer for mucus, allergies, and lung inflammation 12:40 – Why vitamin D is your immune system's most powerful tool 16:20 – The science of inflammatory cytokines and how they damage your lungs 20:10 – Vitamin D studies: 10,000 IU protocol for flu prevention 24:35 – NAC and glutathione: Your body's master antioxidants explained 28:50 – Why people with fatty liver get sicker from viral infections 32:15 – Lysine, zinc, and selenium: Additional immune support nutrients 36:40 – The IV therapy protocol for sick patients in clinical practice 40:20 – Supporting your adrenal glands after flu infection 43:15 – HRV tracking and how to measure your body's stress response 46:00 – Product recommendations: The D, NAC+, Zen, and Gut Powder RESOURCES NAC Benefits for Health – https://www.drugs.com/medical-answers/nac-benefit-health-3573010/ Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths – https://pmc.ncbi.nlm.nih.gov/articles/PMC7231123/ Vitamin D and Respiratory Health – https://pmc.ncbi.nlm.nih.gov/articles/PMC4488782/ The Antioxidant Role of Non-Vitamin, Non-Mineral Micronutrients – https://pmc.ncbi.nlm.nih.gov/articles/PMC8234027/ N-Acetylcysteine and Respiratory Diseases – https://pmc.ncbi.nlm.nih.gov/articles/PMC11278452/ The Role of Zinc in Antiviral Immunity – https://pmc.ncbi.nlm.nih.gov/articles/PMC8349606/ Selenium Supplementation and Influenza Vaccine Response – https://brieflands.com/journals/jkums/articles/69746 Selenium and Viral Infections – https://pmc.ncbi.nlm.nih.gov/articles/PMC6769590/ Immune Activation and Autonomic Nervous System in Post-Viral Fatigue – https://pmc.ncbi.nlm.nih.gov/articles/PMC10795785/ Long COVID and Heart Rate Variability Study – https://www.cidrap.umn.edu/covid-19/long-covid-changes-heart-rate-variability-study-suggests CONNECT

Healthy Matters - with Dr. David Hilden
S05_E05 - Antibiotics - When They're Strong vs. When They're Wrong

Healthy Matters - with Dr. David Hilden

Play Episode Listen Later Dec 7, 2025 28:39 Transcription Available


12/07/25The Healthy Matters PodcastS05_E05 - Antibiotics - When They're Strong vs. When They're WrongWith Special Guest: Dr. Caitlin Eccles-RadtkeAntibiotics have been around for almost a century, in that time they've been responsible for saving countless lives - in both humans and in livestock.  But these meds have gone from medical marvels to "use with caution" in recent times.  But what's driving this change?  When are antibiotics actually called for and when are they ineffective?  And what's the latest on these antibiotic resistant superbugs?Antibiotics have stirred up some big conversations recently, and on Episode 5 of our show, we'll be joined by infectious disease expert Dr. Caitlin Eccles-Radtke to explore the myths, mishaps, and mind-blowing discoveries shaping antibiotic use today.  Wanna know why your doctor side-eyes unnecessary Z-packs?  This episode breaks it all down.  Join us!Got healthcare questions or ideas for future shows?Email - healthymatters@hcmed.orgCall - 612-873-TALK (8255)Get a preview of upcoming shows on social media and find out more about our show at www.healthymatters.org.

Ranch It Up
Prevent Scours Before Calving Season & Cattle Industry News

Ranch It Up

Play Episode Listen Later Dec 7, 2025 27:00


It's The Ranch It Up Radio Show! Join Jeff Tigger Erhardt, Rebecca Wanner AKA BEC and their crew as they hear how feeding Farmatan to bred cows now can help prevent scours this upcoming calving season.  Plus news, markets, updates, bred cow prices and lots more on this all-new episode of The Ranch It Up Radio Show.  Be sure to subscribe on your favorite podcasting app or on the Ranch It Up Radio Show YouTube Channel. How To Prevent Calf Scours: Feed Farmatan   Feed Farmatan To Prevent Scours This Upcoming Calving Season Calving season is getting ready to start for many producers and for some others it is still a ways away yet.  Regardless, we need to get a jump on scours and make sure each and every calf that hits the ground has the best chance of survival.  A simple solution… FARMATAN from Imogene Ingredients.   WHAT CAUSES SCOURS IN BEEF CATTLE/CALVES Clostridia-Enterotoxemia The most common form of Clostridium in cattle is caused by Clostridia perfringens. The gram-positive bacteria are a challenge due to its ability to form spores and lay dormant for long-periods of time. The bacteria reproduce by releasing spores into its environment (soil, feed, manure). The spores can even lay dormant in the animal's intestine until opportunity presents itself. Infection takes place either through ingestion of spores or through an open wound. The most severe cases happen within the first month of a calf's life, and can result in sudden death. Clinical Signs Diarrhea - Bloody, Mucus Present, Bubbly Dehydrated Bloat Blindness Prevention/Treatment: Prevention can be difficult due to the Clostridia spores being extremely durable and present almost everywhere. Complete cleanout and disinfection between calves is helpful, but not always effective. A good vaccination program will reduce clinical disease. The best method is to develop good gut health and the immune system of the calf. Farmatan has been shown to strengthen the intestinal wall, helping to prevent infection from taking hold. Coccidiosis Cattle are host to numerous species of Coccidia, a single-celled protozoal parasite. Infection and clinical symptoms can happen any time during a calf's life, with the most severe reaction usually occurring between 3-6 weeks of age. The life-cycle of coccidia requires time to infect the intestine causing destruction of the mucosal and epithelial lining. The oocytes mature outside the host in warm, moist environments before being consumed, causing infection of a new host. Clinical Signs Diarrhea - Watery, Bloody Depression Weight Loss Prevention/Treatment: Prevention of Coccidiosis is possible by keeping young calves separate from older animals, providing clean water and feed, and dry conditions. Isolation of infected animals is key to preventing transmission. Keeping the pen dry is the most important step a farmer/rancher can take in preventing Coccidiosis. Treatment can have a good impact on reducing secondary disease, and speeding up recovery time. Farmatan has been shown to disrupt the reproductive cycle of Coccidia; and may help strengthen the intestinal wall to prevent infection, in both the cow and calf. Coronavirus Bovine Coronavirus is a ubiquitous, envelope-viral disease, causing respiratory and enteric infection. There are many serotypes for this virus, making it difficult to test for, and create a vaccine. Coronavirus can present as either diarrhea and/or respiratory illness; transmitted through nasal discharge and/or feces. Animal reservoirs continue to spread the disease, and make eradication almost impossible. Clinical disease will likely occur between days 10-14, and present for up to 4 days. Clinical Signs Diarrhea - Watery Nasal Discharge Coughing Prevention/Treatment: Prevention is difficult due to wild animals transmitting the disease. Keeping wild animals out of animal enclosures is essential. Isolation of infected animals is critical to preventing the spread of Coronavirus. Adequate colostrum intake, along with a good vaccination program will help prevent clinical disease. Learn more about the positive effects of Farmtan's active ingredient on Coronavirus HERE. Cryptosporidium Cryptosporidium Parvum is a single-celled parasite responsible for causing infection in young calves. The infection takes place within the first four weeks of a calves' life, afterwards immunity has developed within the calf. The parasite is either passed from the cow or spread through infected water sources. Clinical Signs Diarrhea - Watery, Bloody, Mucus present Colic Depression Prevention/Treatment: Good sanitary conditions, especially clean water is essential in preventing transmission of cryptosporidium. Isolation of sick calves will help reduce the effect on the overall herd. There is some good effect of calves given adequate colostrum, however this is likely helping by reducing other pathogenic loads rather than a direct effect on Cryptosporidium, itself. Farmatan fed prior to calving has been shown to disrupt the life-cycle and reduce transmission from the cow. The direct action of Farmatan on the parasite makes it an excellent choice for treating calves. Learn more about the positive effect of Farmatan's active ingredient HERE. E-Coli Escherichia Coli is a bacterial infection that affects calves within the first week of their life. The bacteria colonize in the lower intestine and produce a toxin. The toxin causes excessive secretion of fluids. The zoonotic disease has special importance in food safety and human health. Colostrum and natural immunity are often not sufficient in preventing infection in cases of high bacterial concentrations. Clinical Signs Diarrhea - Creamy, Yellow Abdominal Pains Fever Vomiting Prevention/Treatment: The best prevention methods for E. Coli include: clean water, dry bedding/environment, isolation of infected animals, and vaccination. Treatment with antibiotics and oral fluids have great benefits in reducing clinical symptoms of the disease. Farmatan has been shown to reduce bacterial load and help prevent infection. Learn more about the positive effects of Farmatan's active ingredient HERE. Rotavirus Rotavirus in calves is caused by a virus belonging to the Reoviridae family, as a non-envelope RNA virus. Rotavirus is thought to be the most common cause of neonatal diarrhea in calves. The virus tends to affect calves between the age of 1-day-old up to a month, with most cases presenting within the first week of life. Shedding and reinfection can happen in older calves and cows. Clinical symptoms are rarely present after the first month of life; older animals tend to either be carriers or asymptomatic. The majority of herds have some level present, with transmission likely happening during or shortly after birth. Clinical Signs Diarrhea - Pale Yellow, Bloody Dehydrated Dull calves Reluctant to drink Prevention/Treatment: The ideal scenario is to prevent infection through, sanitary facilities (calving barn), outdoor calf housing, and a good vaccination program. Colostrum will provide much needed antibodies, protecting the calf before their immune system is fully developed to combat the disease. Farmatan fed prior to calving can help reduce the pathogen load of the cow, reducing the likelihood of transmission. Farmatan supplemented in the milk has been shown to decrease the virus' ability to cause infection and clinical disease. The best treatment for calves already presenting clinical disease is to administer oral fluids/electrolytes to rehydrate the calf. Learn more about the positive effect of Farmatan's active ingredient HERE. Salmonella Salmonella infection of cattle is caused by a variety of species within the family. While the disease is uncommon in cattle with little effect on calf health, it has massive implications for human health and food safety. The bacteria spreads through direct contact or contaminated feed & water. This disease is highly regulated by the USDA. The most severe cases of salmonella affect calves between the ages of 7-10 days old. Clinical Signs Diarrhea - Bloody (flakes of slough tissue), Watery, Mucus present Lethargic Fever Prevention/Treatment: Prevention is always the best option: provide clean water, feed, and bedding. Isolate infected animals, ensure adequate colostrum intake, and develop a vaccination program with your veterinarian. Treatment with antibiotics and fluids (oral or intravenous) greatly increases the survival rate of calves infected with Salmonella. Farmatan has been shown to help reduce the likelihood of infection by protecting the gut, and reduce recovery time of infected animals.  LEARN MORE ABOUT IMOGENE INGREDIENTS  PRODUCTS Paul Mitchell & Paul Martin on RFD TV Rural America Live!  WATCH: https://vimeo.com/759549430/bd063fcc1f Beef Industry News Possible Slow Beef Trend in 2026 According To Rabobank Beef production by major global producers is expected to remain sluggish next year, according to analysts at the Dutch financial services cooperative Rabobank. The recent contraction in beef production is expected to affect major producers in Brazil, Canada and the United States, with New Zealand being likely to see the sharpest percentage drop in beef production, the Rabobank report predicted. Several issues are contributing to the 2025 decline and the expected drop next year, especially in light of limited cattle herds ready for slaughter in both the United States and Brazil, the report added. The long-term contraction of available cattle is being blamed for significant price hikes for retail beef in the last few years, Rabobank noted. Canada is experiencing a tighter pattern that has resulted in a decline of 41,000 metric tons of beef available for export in 2025 versus levels in 2024, according to the report. Canadian beef output in 2026 is expected to be “more limited” compared with this year for reasons also being experienced south of the Canadian border in terms of the available cattle herd. References: https://meatingplace.com/slower-beef-production-trend-to-continue-in-2026-rabobank/?utm_source=omeda&utm_medium=email&utm_cid=1103020073&utm_campaign=MTGMCD251201004&utm_date=20251201-1300 New World Screwworm Website Tracks Parasite There's a new way for producers and other stakeholders to track the fight against the New World Screwworm — a parasite that threatens live cattle herds. The USDA has launched a dedicated website with up-to-date information on the spread of the screwworm, which so far has been confined to cattle in several Mexican states near the U.S. border. The site includes resources for livestock producers, veterinarians, animal-health officials, wildlife experts, healthcare providers, pet owners, researchers, drug manufacturers, and the general public. Reports of the pest in Mexican cattle prompted the U.S. to halt cattle imports from Mexico back in May. USDA also committed $21 million to boost sterile fly production in Mexico as part of its response. The new website pulls together information from multiple federal partners, including the FDA, the Department of Energy, Homeland Security, the EPA, and the State Department.  Reference: https://www.aphis.usda.gov/livestock-poultry-disease/stop-screwworm Nightshade In Corn Residue Could Be Toxic Have you noticed any black nightshade in your corn stalks that you are grazing or plan to graze? If these fields have too much black nightshade, be careful — it might be toxic. Black nightshade is common in many corn fields in the fall, especially those that had hail damage in the summer or any situation where the corn canopy became thin or open. It usually isn't a problem, but if the density of nightshade is very high, there is the potential that it could poison livestock. Almost all livestock, including cattle, sheep, swine, horses and poultry are susceptible.   Black nightshade plants average about two feet in height and have simple alternating leaves. In the fall, berries are green and become black as the plant matures. All plant parts contain some of the toxin and the concentration increases as plants mature, except in the berries. Freezing temperatures will not reduce the toxicity. It is very difficult to determine exactly how much black nightshade is risky. Guidelines say that a cow would need to consume three to four pounds of fresh black nightshade to be at risk of being poisoned. These guidelines, though, are considered conservative since there is little data on the actual toxicity of nightshade plants. Fortunately, even though nightshade plants remain green fairly late into the fall, cattle usually don't appear to seek out nightshade plants to graze. However, green plants of nightshade might become tempting toward the end of a field's grazing period when there is less grain, husks or leaves to consume.  References: https://www.nationalbeefwire.com/nightshade-in-corn-residue-grazing-could-be-toxic Featured Experts in the Cattle Industry Paul Mitchell – Imogene Ingredients https://www.imogeneingredients.com/ Follow on Facebook: @FarmatanUSA Kirk Donsbach – Financial Analyst at StoneX https://www.stonex.com/ Follow on Facebook: @StoneXGroupInc Shaye Wanner – Host of Casual Cattle Conversation https://www.casualcattleconversations.com/ Follow on Facebook: @cattleconvos Contact Us with Questions or Concerns Have questions or feedback? Feel free to reach out via: Call/Text: 707-RANCH20 or 707-726-2420 Email: RanchItUpShow@gmail.com Follow us: Facebook/Instagram: @RanchItUpShow YouTube: Subscribe to Ranch It Up Channel: https://www.youtube.com/c/RanchItUp Catch all episodes of the Ranch It Up Podcast available on all major podcasting platforms. Discover the Heart of Rural America with Tigger & BEC Ranching, farming, and the Western lifestyle are at the heart of everything we do. Tigger & BEC bring you exclusive insights from the world of working ranches, cattle farming, and sustainable beef production. Learn more about Jeff 'Tigger' Erhardt & Rebecca Wanner (BEC) and their mission to promote the Western way of life at Tigger and BEC. https://tiggerandbec.com/ Industry References, Partners and Resources For additional information on industry trends, products, and services, check out these trusted resources: Allied Genetic Resources: https://alliedgeneticresources.com/ American Gelbvieh Association: https://gelbvieh.org/ Axiota Animal Health: https://axiota.com/multimin-campaign-landing-page/ Imogene Ingredients: https://www.imogeneingredients.com/ Jorgensen Land & Cattle: https://jorgensenfarms.com/#/?ranchchannel=view Medora Boot: https://medoraboot.com/ RFD-TV: https://www.rfdtv.com/ Rural Radio Network: https://www.ruralradio147.com/ Superior Livestock Auctions: https://superiorlivestock.com/ Transova Genetics: https://transova.com/ Westway Feed Products: https://westwayfeed.com/ Wrangler: https://www.wrangler.com/ Wulf Cattle: https://www.wulfcattle.com/

Microbe Magazine Podcast
Clinical Trials With the Potential To Change the Management of Prosthetic Joint Infections

Microbe Magazine Podcast

Play Episode Listen Later Dec 6, 2025 47:14


Prosthetic joint infections (PJI) remain among the most devastating complications in orthopedic surgery, with increasing incidence paralleling the growth in arthroplasty procedures worldwide. While treatment protocols are well-established, evidence supporting current approaches is lacking, and outcomes remain suboptimal, highlighting the need for improved therapeutic strategies. AAC recently published a minireview of randomized controlled trials and emerging evidence for the management for these difficult to treat infection. Today, we discuss with one of the authors of the manuscript and an ID doctor specialized in PJI infections the findings of such paper. Topics discussed: Challenges of treating prosthetic joint infections. Major clinical trial data supporting different approaches for treatment and prevention of PJI Guidance for the approach to these complicated infections. Guests: David Paterson MBBS, Ph.D., Professor, Saw Swee Hock School of Public Health (Joint) Yong Loo Lin School of Public Health (Joint), Director, ADVANCE-ID, National University of Singapore, Singapore.  Ana Victoria Salas-Vargas, M.D. Assistant Professor of Clinical Medicine, Houston Methodist Academic Institute and Weill Cornell Medical College.  This episode is brought to you by the Antimicrobial Agents and Chemotherapy Journal.  Visit asm.org/aac to browse issues and/or submit a manuscript. If you plan to publish in AAC, ASM Members get up to 50% off publishing fees. Visit asm.org/joinasm to sign up.

What the Health?
The GOP Still Can't Agree on a Health Plan

What the Health?

Play Episode Listen Later Dec 4, 2025 44:43


Senate Democrats were promised a vote by mid-December on extending the enhanced subsidies for the Affordable Care Act, but Republicans still can't decide whether they want to put forward their own alternative or what that might include. Meanwhile, both the Centers for Disease Control and Prevention and the Food and Drug Administration are roiled by debates over vaccines. Alice Miranda Ollstein of Politico, Joanne Kenen of the Johns Hopkins Bloomberg School of Public Health and Politico Magazine, and Paige Winfield Cunningham of The Washington Post join KFF Health News' Julie Rovner to discuss those stories and more. Also this week, Rovner interviews KFF Health News' Aneri Pattani about her project tracking the distribution of $50 billion in opioid legal-settlement payments.  Plus, for “extra credit” the panelists suggest health policy stories they read this week that they think you should read, too: Julie Rovner: The New York Times' “These Hospitals Figured Out How To Slash C-Section Rates,” by Sarah Kliff and Bianca Pallaro.  Joanne Kenen: Wired's “A Fentanyl Vaccine Is About To Get Its First Major Test,” by Emily Mullin.  Paige Winfield Cunningham: The New York Times' “A Smartphone Before Age 12 Could Carry Health Risks, Study Says,” by Catherine Pearson.  Alice Miranda Ollstein: The Independent's “Miscarriages, Infections, Neglect: The Pregnant Women Detained by ICE,” by Kelly Rissman.  

The Birth Trauma Mama Podcast
Ep. 208: Rushed to the NICU: Navigating Pneumothorax, Infection Fears, and Postpartum Chaos ft. Kelsea

The Birth Trauma Mama Podcast

Play Episode Listen Later Dec 4, 2025 29:57


In this episode of The Birth Trauma Mama Podcast, Kayleigh sits down with Kelsea, a mom of three, to share the emotional, terrifying, and deeply transformative story of her son Oliver's birth and NICU journey a birth she hoped would finally be a peaceful experience after two difficult deliveries, but instead became her most traumatic one yet.Scheduled for a repeat C-section at 37 weeks due to rising blood pressures and a history of preeclampsia, Kelsea entered the hospital with a pit in her stomach,  a feeling she now knows was intuition. The days that followed were filled with fear and uncertainty. Oliver deteriorated quickly, and for 24 hours, doctors weren't sure what was wrong. Finally, a NICU physician discovered that he had a pneumothorax, a collapsed left lung, and early signs of sepsis. He was intubated, placed on chest tubes, and put under strict no-hold restrictions leading to a heartbreaking stretch where Kelsea couldn't touch, comfort, or even pick up her newborn son.Together, Kayleigh and Kelsea talk through:

American Journal of Gastroenterology - Author Podcasts
Infections in Standard or Tapered Dose of Prednisolone for Alcohol-Associated Hepatitis: A Randomized Trial (STASH Trial)

American Journal of Gastroenterology - Author Podcasts

Play Episode Listen Later Dec 3, 2025 9:35


Youth BiOY
Day 335: How to Avoid Spiritual Infections

Youth BiOY

Play Episode Listen Later Dec 1, 2025 13:40


Psalm 136:23-26, Daniel 7:1-14, 1 John 2:12-27. Yet you have the powerful spiritual ‘antiseptic' to use against these destructive forces It is vital that you learn to do so

Bible In One Year Express
Day 335: How to Avoid Spiritual Infections

Bible In One Year Express

Play Episode Listen Later Dec 1, 2025 14:08


Psalm 136:23-26, Daniel 7:1-14, 1 John 2:12-27. Yet you have the powerful spiritual ‘antiseptic' to use against these destructive forces It is vital that you learn to do so

Communicable
Communicable E41: Diagnostic stewardship

Communicable

Play Episode Listen Later Nov 30, 2025 62:07


In the last ten years, 'diagnostic stewardship' has emerged as a core principle of good clinical practice whose implementation impacts both the individual patient and public health at large. In this episode of Communicable, hosts Angela Huttner and Annie Joseph invite two experts in the field, Daniel Morgan (Maryland, USA) and Valerie Vaughn (Utah, USA), to discuss diagnostic stewardship in the context of infectious diseases, hospital medicine, and healthcare in general. Other topics covered include practical interventions for better testing practices and the role of artificial intelligence in the future of diagnostics. The episode highlights how thoughtful, intentional diagnostic practices can enhance clinician workflows and improve patient outcomes.This episode is a follow-up from Morgan's recently published commentary in CMI Communications on diagnostic testing, and the need for evaluating its clinical impact [1]. The episode was peer reviewed by Özlem Türkmen Recen of Çınarcık State Hospital, Yalova, Türkiye. ReferencesBaghdadi JD & Morgan DJ. Diagnostic tests should be assessed for clinical impact. CMI Comms 2024. DOI: 10.1016/j.cmicom.2024.105010Further readingAdvani S and Vaughn VM. Quality Improvement Interventions and Implementation Strategies for Urine Culture Stewardship in the Acute Care Setting: Advances and Challenges. Curr Infect Dis Rep 2021. DOI: 10.1007/s11908-021-00760-3 Core Elements of Hospital Antibiotic Stewardship Programs, https://www.cdc.gov/antibiotic-use/hcp/core-elements/hospital.html Core Elements of Hospital Diagnostic Excellence (DxEx), https://www.cdc.gov/patient-safety/hcp/hospital-dx-excellence/index.htmlCosgrove SE & Srinivasan A. Antibiotic Stewardship: A Decade of Progress. Infect Dis Clin North Am 2023. DOI: 10.1016/j.idc.2023.06.003 Dik JH, et al. Integrated Stewardship Model Comprising Antimicrobial, Infection Prevention, and Diagnostic Stewardship (AID Stewardship). J Clin Microbiol 2017. DOI: 10.1128/jcm.01283-17Fabre V, et al. Principles of diagnostic stewardship: A practical guide from the Society for Healthcare Epidemiology of America Diagnostic Stewardship Task Force. Infect Control Hosp Epidemiol 2023. DOI: 10.1017/ice.2023.5 Huttner A, et al. Re: ‘ESR and CRP: it's time to stop the zombie tests' by Spellberg et al. CMI 2025. DOI: 10.1016/j.cmi.2024.09.016 Morgan DJ, et al. Diagnostic Stewardship—Leveraging the Laboratory to Improve Antimicrobial Use. JAMA 2017. DOI:  10.1001/jama.2017.8531 Messacar K, et al. Implementation of rapid molecular infectious disease diagnostics: the role of diagnostic and antimicrobial stewardship. J Clin Microbiol 2017. DOI: 10.1128/jcm.02264-16Messacar K, et al. Clinical and Financial Impact of a Diagnostic Stewardship Program for Children with Suspected Central Nervous System Infection. J Pediatr. 2022. DOI: 10.1016/j.jpeds.2022.02.002  Qian ET, et al. Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial. JAMA 2023. DOI: 10.1001/jama.2023.20583 Siontis KC et al. Diagnostic tests often fail to lead to changes in patient outcomes. J Clin Epidemiol 2014. DOI: 10.1016/j.jclinepi.2013.12.008Vaughn VM, et al. Antibiotic Stewardship Strategies and Their Association With Antibiotic Overuse After Hospital Discharge. Clin Infect Dis 2022. DOI: 10.1093/cid/ciac104Vaughn VM, et al. A Statewide Quality Initiative to Reduce Unnecessary Antibiotic Treatment of Asymptomatic Bacteriuria. JAMA Intern Med 2023. DOI: 10.1001/jamainternmed.2023.2749  

Vitality Radio Podcast with Jared St. Clair
#591: Homeopathy Made Simple: A Powerful, Safe, Natural Medicine for the Whole Family with Paola Brown

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Nov 29, 2025 72:16


On this episode of Vitality Radio, Jared welcomes homeopathy educator and advocate Paola Brown, president of Americans for Homeopathy Choice. Together, they break down what homeopathy really is, how it works, and why it continues to help families around the world—even when the mainstream medical world insists it “shouldn't.” Paola shares her personal healing story, practical guidance for beginners, simple ways parents can confidently use homeopathy for everyday acute issues, and when to seek support from a homeopath for chronic conditions. You'll also hear why the FDA has recently threatened access to homeopathic remedies and what Paola's organization is doing in Washington, D.C. to keep these safe, affordable remedies available for everyone. Jared and Paola discuss potency selection, how to identify the right remedy, and why homeopathy often succeeds where other natural tools don't—especially for children and even animals. If you've ever been curious, skeptical, or confused about homeopathy, this conversation makes the entire system feel approachable, actionable, and empowering. And if you're already a believer, you'll walk away with even more tools, stories, and insights to support your family's wellness—naturally and safely.Products:Ollois Homeopathic RemediesAdditional Information:PaolaBrown.com/freeHomeopathyChoice.org/freeTo schedule your Homeopathy Consultation with Amanda Kotter:Email Amanda@vitalitynutrition.comCall/Text 801-388-4133Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

My Happy Thyroid
Ep. 245: Viral Triggers: When Infections Spark Hashimoto's

My Happy Thyroid

Play Episode Listen Later Nov 28, 2025 13:37


Could a past virus be the missing link behind your Hashimoto's? In this episode of Paloma's My Thyroid Health podcast, we unravel the hidden connection between viral infections and Hashimoto's thyroiditis — and what that means for your health.Join Paloma Health as we explore:How your immune system's fight against a virus can backfire, triggering an autoimmune attack on your thyroid through a phenomenon called molecular mimicry. The surprising way certain viruses—like EBV, CMV, enteroviruses, and even COVID-19—may directly infect thyroid cells, fueling chronic inflammation and autoimmune flares. Why some viral infections lie dormant only to reawaken later, reactivating your immune system and worsening thyroid autoimmunity. Real-world strategies for supporting your thyroid when viral triggers are involved: immune resilience, monitoring, and balancing inflammation. If you've ever wondered why your Hashimoto's symptoms flare, or felt like your thyroid health has chronically “off” sessions — this episode shines a light on a lesser-known piece of the puzzle. 

The Orthobullets Podcast
Podiums |Trauma | DAA THA: My Wound Care Protocol and Prevention of Infection

The Orthobullets Podcast

Play Episode Listen Later Nov 27, 2025 11:22


Welcome to Season 2 of the Orthobullets Podcast. Today's show is Podiums, where we feature expert speakers from live medical events. Today's episode will feature ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Dr. H. John Cooper is titled⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ "⁠⁠⁠DAA THA: My Wound Care Protocol and Prevention of Infection⁠⁠⁠⁠."Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Orthobullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on Social Media:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YouTube

The Conversation Weekly
The 40 scientists who decide which flu shot you'll get

The Conversation Weekly

Play Episode Listen Later Nov 27, 2025 26:05


Twice a year, 40 scientists gather together for five days to decide what strains of influenza to vaccinate against for the next flu season. It takes around six months to prepare the vaccine – which usually includes protection against three different strains of flu. Europe and the US are heading into a flu season that some are warning could be particularly severe this winter. While even as summer approaches in Australia, the country is still registering high numbers of cases after a record-breaking flu season earlier in the year. So how does the process of deciding on a flu vaccine each year actually work? And does what happens in the southern hemisphere influence the way the virus circulates in the northern hemisphere? In this episode, we speak to Ian Barr, deputy director for the WHO Collaborating Centre for Reference and Research on Influenza, based at the Peter Doherty Institute for Infection and Immunity, part of the University of Melbourne. Barr is one of those 40 scientists who attend the meetings to decide what strains to focus vaccination efforts on. This episode was produced by Mend Mariwany, Katie Flood and Gemma Ware. Mixing by Michelle Macklem and theme music by Neeta Sarl. Read the full credits for this episode and sign up here for a free daily newsletter from The Conversation.If you like the show, please consider donating to The Conversation, an independent, not-for-profit news organisation.First human bird-flu death from H5N5 – what you need to knowFlu season has arrived – and so have updated flu vaccinesFlu season has started early in the UK – here's what might be going on

Life in Medicine
#65 - LiM - Less stress with infection

Life in Medicine

Play Episode Listen Later Nov 27, 2025 60:35


Andrew Fravel is a recent orthopaedic graduate with a strong interest in joint replacement infection. More importantly he calm and balanced approach to his work life balance. 

CCO Infectious Disease Podcast
Optimizing Antibiotics in Acute Bacterial Skin and Skin Structure Infections for Today

CCO Infectious Disease Podcast

Play Episode Listen Later Nov 26, 2025 45:41


Listen in as experts Thomas P. Lodise, PharmD, PhD, and George Sakoulas, MD, FIDSA, explore tailored antibiotic strategies for diverse patients with acute bacterial skin and skin structure infections (ABSSSIs). Their insightful discussion focuses on antibiotic developments that followed publication of the IDSA practice guidelines in 2014 and the challenges unique to ABSSSIs, including a lack of determined bacterial etiology for many cases. PresentersThomas P. Lodise, PharmD, PhDProfessorAlbany College of Pharmacy and Health SciencesInfectious Diseases Clinical Pharmacy SpecialistStratton VA Medical CenterAlbany, New YorkGeorge Sakoulas, MD, FIDSAChief, Infectious DiseasesSharp Rees-Stealy Medical GroupAdjunct Professor of PediatricsUniversity of California San Diego School of MedicineSan Diego, CaliforniaLink to full program:https://bit.ly/4oIKwzsGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The Naked Scientists Podcast
New ways to combat the Antibiotic Apocalypse

The Naked Scientists Podcast

Play Episode Listen Later Nov 25, 2025 32:49


Today, synthetic bacteriophages, a breakthrough vaccine for TB, and how unpicking the pathways used to make antibiotics are helping scientists to combat rising rates of antimicrobial resistance around the world... Like this podcast? Please help us by supporting the Naked Scientists

Rheuminations
The history of giant cell arteritis: Infections, injections and the man who couldn't wear a hat

Rheuminations

Play Episode Listen Later Nov 25, 2025 42:30


What does a goiter and syphilis have in common with the first descriptions of giant cell arteritis? Join us as we dive into the history of the most common type of vasculitis! Intro 0:13 GCA at ACR 2025 00:30 How Brown has approached framing this episode 1:01 A primer leading us to GCA 3:15 Let's get to the story 4:02 The man who couldn't wear a hat 4:57 Dr. Bayard Horton's 7:40 A tangent on cluster headaches 8:27 Let's get back to GCA 13:16 The first temporal artery biopsy 14:28 Vision loss and other puzzle pieces of GCA 16:27 What about jaw claudication? 21:15 Could GCA be transmissible? Injecting ground temporal arteries into healthy volunteers 24:13 Oxygen? Histamines? Adrenal cortical extract? Looking for GCA treatments 26:55 Steroids and GCA 28:40 A quote from the 1959 Mayo Clinic Board of Governors 32:24 Extracranial involvement in GCA 33:24 When did we recognize aorta involvement? Syphilis enters the picture 35:08 A recap of the history of GCA 41:25 Thanks for listening 42:19 We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum. References: Boes CJ, Cephalalgia. 2007;doi:10.1111/j.1468-2982.2007.01238.x Cummer CL, et al. JAMA. 1912;doi:10.1001/jama.1912.04270080101004 Horton BT, Proc Cent SOC Clin Res. 1946 Sproul EE, et al. Am J Pathol. 1937;PMID: 19970328 Disclosures: Brown reports no relevant financial disclosures.

Tick Boot Camp
Episode 545: Using the Human Eye to Detect Early Alzheimer's and Infection-Induced Brain Changes – Dr. Sean Miller (Yale)

Tick Boot Camp

Play Episode Listen Later Nov 25, 2025 11:19


Overview This special episode of the Tick Boot Camp Podcast was recorded live at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and PCOM Symposium in collaboration with Pathobiome Perspectives. Hosted by Ali Moresco in partnership with Nikki Schultek, Executive Director of AlzPI, the conversation brings the Tick Boot Camp mission of exploring infection-associated chronic illness (IACI)—including Lyme disease and other tick-borne infections—to the global Alzheimer's and neuroimmunology research community. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen partnered with Ali and Nikki to highlight leading scientists connecting infection, immune dysfunction, and cognitive decline. This episode features Dr. Sean Miller, a neuroscientist and co-investigator in the Logan Lab with a primary appointment at Yale School of Medicine, who is developing ways to non-invasively detect Alzheimer's-like pathology through the eye. Guest Sean Miller, PhD Co-Investigator, Logan Lab / Yale School of Medicine Dr. Sean Miller completed pre-doctoral work at Harvard Medical School, earned his PhD from Johns Hopkins University, and completed post-doctoral training at Stanford University. His research focuses on neurodegeneration, neuroglia, and early diagnostic strategies for Alzheimer's and related diseases. At the AlzPI & PCOM Symposium, Dr. Miller presented evidence showing that SARS-CoV-2 (COVID-19) infection can accelerate Alzheimer's-like pathology and that these changes can be detected non-invasively through retinal imaging. His findings suggest that amyloid-beta, a protein long associated with Alzheimer's disease, may also serve as part of the brain's antimicrobial defense system—trapping pathogens like a mesh or biofilm, but leading to damaging plaque buildup when overproduced. Key Discussion Points Dr. Miller describes how the COVID-19 virus can act as an infectious trigger for neuroinflammation and amyloid buildup, how the eye provides a unique window into the brain, and why early detection is essential to preventing neuron death. He shares how his lab's AI-enhanced retinal imaging research at Yale Eye Center is identifying amyloid and tau deposits in patients with long COVID-related brain fog—opening the possibility of routine eye exams doubling as early Alzheimer's screening tools. He explains potential therapeutic strategies, such as limiting amyloid production during infection flare-ups and enhancing clearance mechanisms afterward to reduce chronic plaque formation. The conversation also explores his scientific journey—from designing Alzheimer's drugs at Harvard and Johns Hopkins to realizing the need for early disease detection during his postdoc at Stanford—and how the pandemic inspired his focus on infection-induced neurodegeneration. “We believe neurons are exposed to pathogens in the central nervous system and respond by secreting amyloid-beta to trap them. Excessive plaque buildup from repeated or severe infections may be what drives long-term neurodegeneration.” — Dr. Sean Miller Why It Matters Dr. Miller's research connects infectious disease, ophthalmology, and neurology, providing a revolutionary new method to screen for early Alzheimer's-like changes non-invasively through the human eye. His work suggests that infections like COVID-19 may trigger the same protective—but damaging—immune responses implicated in chronic conditions such as Alzheimer's disease and infection-associated cognitive decline. About the Event The interview took place at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and Philadelphia College of Osteopathic Medicine (PCOM) Symposium, held on October 3, 2025, at Ohio University in Dublin, Ohio. The event brought together more than 20 global researchers exploring how microbes, the microbiome, and the immune response contribute to Alzheimer's, dementia, PANS/PANDAS, and infection-associated chronic illnesses (IACI). Tick Boot Camp partnered with Ali Moresco and Nikki Schultek to share the voices of researchers advancing the field of infection-associated chronic illness. This episode is part of a multi-part Tick Boot Camp series highlighting how pathobiome and microbiome science are transforming the understanding of Lyme disease, infection, and neurodegeneration. Learn More Learn more about the Alzheimer's Pathobiome Initiative (AlzPI) Listen to Tick Boot Camp Podcast episodes, including Episode 406: Pathobiome – An Interview with Nikki Schultek and Episode 101: The Young Gun – An Interview with Alex (Ali) Moresco discussed in this interview.

Aging-US
Hospital Infections Associated with Higher Risk of Dementia

Aging-US

Play Episode Listen Later Nov 25, 2025 3:37


BUFFALO, NY — November 25, 2025 — A new #research paper was #published in Volume 17, Issue 10 of Aging-US on October 13, 2025, titled “Hospitalization with infections and risk of Dementia: a systematic review and meta-analysis.” This large-scale meta-analysis, led by first author Wei Yu Chua from the National University of Singapore and corresponding author Eng-King Tan from the National Neuroscience Institute and Duke-NUS Medical School in Singapore, shows that adults hospitalized with infections have a significantly higher risk of developing dementia. The findings are especially important as global populations grow older and hospitalizations for infections increase, highlighting a potential new approach for dementia prevention. “Out of 1900 studies that were screened initially, 16 studies comprising 4,266,276 patients were included for analysis.” The researchers analyzed data from over 4 million individuals across 16 studies, making this study the most comprehensive review to date on the association between infection-related hospital stays and long-term brain health. The results showed that being hospitalized for an infection raised the risk of all-cause dementia by 83%. Among the types of infections studied, sepsis carried the highest risk, followed by pneumonia, urinary tract infections, and skin or soft tissue infections. The risk of developing vascular dementia was notably higher than that of Alzheimer's disease. One possible explanation for the association between infections and dementia is that infections trigger systemic inflammation that may reach the brain. Inflammatory molecules can cross the blood-brain barrier, potentially leading to the buildup of damaging proteins and the death of brain cells. This process may be more severe in older adults, whose immune systems are often slower to respond and recover. The study also suggests that even a single infection-related hospitalization can speed up cognitive decline, especially in individuals already at higher risk. Importantly, the risk of dementia was greatest within the first year following an infection but remained elevated for many years afterward. In fact, studies with follow-ups longer than a decade showed even stronger associations. These results suggest the need for early cognitive monitoring after hospital discharge, particularly in older adults recovering from infections. These findings have important implications for healthcare systems, particularly those serving aging populations, and underscore the lasting impact that infections can have on the brain. This research highlights the importance of looking beyond genetics and lifestyle for prevention strategies. With over 50 million people affected by dementia worldwide and annual care costs in the U.S. exceeding $300 billion, identifying new and preventable risk factors is critical. Reducing infections, improving hospital care, and monitoring brain health after illness may offer promising ways to protect cognitive function in aging populations. DOI - https://doi.org/10.18632/aging.206329 Corresponding author - Eng-King Tan - tan.eng.king@singhealth.com.sg Abstract video - https://www.youtube.com/watch?v=uyv5VHHHIA4 Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206329 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts To learn more about the journal, visit https://www.Aging-US.com​​ and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@Aging-US LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Coach Cody
Burnout, a Spine Infection, and the Wake-Up Call We Didn't See Coming

Coach Cody

Play Episode Listen Later Nov 24, 2025 48:02


The coach cody podcast is back! We get into why we had to stop everything — including a sudden spine infection (dyskitis/osteomyelitis), repeating fevers, a PICC line, and the burnout that had been brewing long before any hospital stay.This is the most honest breakdown we've ever done about stress, burnout, creator pressure, chronic pain, and what happens when your body finally hits the brakes for you.We cover: The full story behind the dyskitis/osteomyelitis diagnosisHospital chaos, fevers, and the 3am “get to the ER now” phone callWhat burnout actually looks like (and why so many people miss it)How stress and overworking can wreck your immune systemThe pressure of being a coach/creator during burnoutIdentity, productivity, and learning to rest without guilt.Dez's perspective as a partner navigating the whole nightmare.Why we're shifting the tone of the show to be more real + sustainableWhat recovery looks like from here — mentally and physically. If you've been feeling burned out, overwhelmed, exhausted, or like you're pushing through when your body is begging you to stop… this episode is for you.

The Divorced Dadvocate
283 - The Infection Stage Before Parental Alienation

The Divorced Dadvocate

Play Episode Listen Later Nov 24, 2025 36:01 Transcription Available


A child's bond doesn't shatter overnight—it frays through small cuts that often go unnoticed. We unpack the idea of “pre-alienation,” the early stage where one parent's subtle comments, eye rolls, and quiet omissions make a child question the other parent's love or competence. Using a clear infection-versus-disease analogy, we show how these patterns multiply over time and why the earliest moments are the best time to intervene.Listeners save 25% on 1-on-1 divorce coaching! Book any coaching between now and the end of the year to claim your discount. Don't just survive this—get a strategic plan.Sign up now: https://thedivorceddadvocate.com/coaching-3/. Enter DADS25 at checkout.Join our Signal Channel: https://shorturl.at/8yqTbJoin The Divorce Dadvocate Membership Community - FULL Episodes - Live Meetings – FREE Workshops & Courses – Private Discussion Groups & MORE! - https://thedivorceddadvocate.com/membership-tiers/How Are You Adjusting To Your Divorce? Find out in this quiz - http://www.thedivorceddadvocate.com/divorce-quiz.html*FREE Dads Guide To Divorce* How to survive and thrive during and after divorce: http://www.dadsguidetodivorce.comDon't suffer in silence! Get relief from the pain and confusion of your divorce and schedule your FREE, No Obligation Coaching Consultation - schedule a time directly into my schedule at www.TalkWithJude.com.Join other divorced dads who have experienced or are experiencing divorce in this FREE Divorced Dads Online Meetup Group - https://www.meetup.com/Divorced-Dads-Meetup-Group/Other Resources:The Divorced Dadvocate Website - http://www.TheDivorcedDadvocate.comThe Divorced Dadvocate YouTube Channel - https://www.youtube.com/watch?v=GeSwx-F8KK4&list=PLT4HyN5ishYJznK51205ESxGZ2d19YkBpThe Divorced Dadvocate Podcast - https://thedivorceddadvocate.buzzsprout.com/Divorced Dads Online Meetup Group - https://www.meetup.com/Divorced-Dads-Meetup-Group/The Divorced Dadvocate Facebook Group - https://www.facebook.com/thedivorceddadvocate/ Listeners save 25% on 1-on-1 divorce coaching! Book any coaching between now and the end of the year to claim your discount. Don't just survive this—get a strategic plan.Sign up now: https://thedivorceddadvocate.com/coaching-3/. Enter DADS25 at checkout. Support the show

Blood Cancer Talks
Episode 67. Management of CMV in Hematologic Malignancies

Blood Cancer Talks

Play Episode Listen Later Nov 23, 2025 40:01


Join hosts Eddie, Ashwin, and Raj as they welcome Dr. Michelle Yong and Dr. Gemma Reynolds, academic infectious diseases physicians from the Peter MacCallum Cancer Centre and the National Centre for Infections in Cancer, for an in-depth discussion on cytomegalovirus (CMV) management in immunocompromised hematology patients.Key Topics CoveredFundamentals of CMV ManagementDistinguishing CMV reactivation from CMV diseaseTreatment thresholds and target viral loadsProphylaxis strategies in non-allograft settingsValaciclovir dosing in general hematology populationsHigh-risk patient populationsFirst-Line TherapiesValganciclovir: advantages, disadvantages, and myelosuppressionFoscarnet: indications and monitoring strategiesTreatment-resistant CMVAllogeneic Transplant PatientsHigh-risk populations and timing of reactivationMonitoring protocols post-transplantRandomized Controlled TrialsAURORA Trial: Maribavir vs. ValganciclovirDesign: RCT comparing maribavir to valganciclovir for pre-emptive CMV therapy post-allogeneic transplant [https://pubmed.ncbi.nlm.nih.gov/38036487/]NEJM Letermovir Prophylaxis TrialDesign: Double-blind, placebo-controlled RCT of letermovir prophylaxis post-allogeneic transplant [https://pubmed.ncbi.nlm.nih.gov/29211658/]Emerging Patient PopulationsCMV in lymphoma and myeloma patients receiving CAR T-cell therapy and T-cell engaging bispecific antibodiesMonitoring and prophylaxis strategies for novel immunotherapiesImpact of CMV on post-CAR T mortality-https://pubmed.ncbi.nlm.nih.gov/40203190/

The Smart 7
The Sunday 7 - Concerns grow over potential AI Bubble, NASA launches new climate monitoring satellite, and the prehistoric history of the first KIss

The Smart 7

Play Episode Listen Later Nov 23, 2025 19:20


The Smart 7 is an award winning daily podcast, in association with METRO that gives you everything you need to know in 7 minutes, at 7am, 7 days a week...With over 19 million downloads and consistently charting, including as No. 1 News Podcast on Spotify, we're a trusted source for people every day and the Sunday 7 won a Gold Award as “Best Conversation Starter” in the International Signal Podcast Awards If you're enjoying it, please follow, share, or even post a review, it all helps...Today's episode includes the following guests:Antonio Guterres - UN Secretary General Ben Hamlington - NASA Research Scientist, and part of Project Sentinel 6BSeverine Fournier - Sentinel 6B Deputy Project Scientist at NASA's Jet Propulsion Labs Doctor Chris Van Tulleken - Author of the study, TV presenter, and aProfessor of Infection and Global Health at University College London Doctor Amir Khan -This Morning's resident GP Will Guyatt - The Smart 7's Tech Guru Dr Matilda Brindle - Lead Researcher and Evolutionary Biologist at Oxford UniversityDoctor Matthew Degennero - Director of the Bio-Molecular Sciences Institute at Florida State UniversityDoctor John Paul Mutebi - Chief of the Mosquito Control Division in Miami Dade CountyJensen Huang - CEO of Nvidia Sundar Pichai - Google CEO Dario Amodei - CEO and Co Founder of Anthropic Shayla Zink - Volunteer at the Morro Bay Marine Mammal Centre Contact us over @TheSmart7pod or visit www.thesmart7.com or find out more at www.metro.co.uk Presented by Ciara Revins, written by Liam Thompson, researched by Lucie Lewis and produced by Daft Doris. Hosted on Acast. See acast.com/privacy for more information.

CCO Infectious Disease Podcast
Overcoming Fear of Virologic Failure: Barriers to Optimizing ART in People Living With HIV and Viral Suppression

CCO Infectious Disease Podcast

Play Episode Listen Later Nov 21, 2025 18:47


Fear of virologic failure is a major barrier to ensuring that people living with virally suppressed HIV are receiving the most optimal antiretroviral therapy (ART) regimen for them. Stream this Medical Minute to learn more about key guideline recommendations regarding ART switch and reassuring clinical data regarding efficacy, tolerability, and quality of life associated with switching a suppressive ART regimen. Topics covered include:Efficacy of switching to 2-drug oral ART: real-world evidenceReal-world analyses of virologic failure with switch to long-acting cabotegravir plus rilpivirinePatient selection to reduce risk of virologic failure with switch Regimen-specific switch considerationsPresenters:Dima Dandachi, MD, MPH, FIDSA, FACPAssociate Professor of MedicineDivision of Infectious DiseasesUniversity of MissouriMedical DirectorHIV Treatment and Prevention Program, MUHCMedical DirectorBoone County Public Health and Human ServicesColumbia, MissouriChloe Orkin, MBChB, FRCP, MDProfessor of Infection and InequitiesDean for Healthcare TransformationQueen Mary University of LondonFaculty of Medicine and DentistryHonorary Consultant PhysicianBarts Health NHS TrustLondon, United KingdomLink to full program and accompanying slides:https://bit.ly/3KPN0xbGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The ASHE Podcast
Episode 25: Stewardship Opportunities in Peripartum Infections

The ASHE Podcast

Play Episode Listen Later Nov 21, 2025 41:53


In this episode of The ASHE Podcast, host Dr. Priya Nori speaks with Dr. Alexia Foy-Crowder, Dr. Pam Bailey, and Dr. Grace Pazienza about their ASHE paper, “Stewardship opportunities in peripartum infections: a review of quality improvement initiatives and future directions” (September 2025). They discuss why they focused on the peripartum population, the unique implementation challenges in obstetric care, and key findings from their study—including the high proportion of mother–baby dyads receiving antimicrobials and the striking variability across 199 identified regimens. The authors reflect on guideline discordance, the frequent presence of penicillin allergy labels, and how these issues create opportunities for stewardship intervention. The conversation also covers practical strategies for engaging obstetric teams, metrics for improving antibiotic use, remaining research gaps, and how stewardship in obstetrics connects to maternal health disparities and global antimicrobial resistance. https://www.cambridge.org/core/journals/antimicrobial-stewardship-and-healthcare-epidemiology/article/stewardship-opportunities-in-peripartum-infections-a-review-of-quality-improvement-initiatives-and-future-directions/BC262D79208E5215F7FF7562B579C6B2#article

PeerVoice Clinical Pharmacology Audio
David Alain Wohl, MD - Inpatient Management of SARS-CoV-2 Infection: Applying Learnings From Real World Evidence to Real World Practice

PeerVoice Clinical Pharmacology Audio

Play Episode Listen Later Nov 21, 2025 38:52


David Alain Wohl, MD - Inpatient Management of SARS-CoV-2 Infection: Applying Learnings From Real World Evidence to Real World Practice

5 Things
When preventable infections turn deadly behind bars

5 Things

Play Episode Listen Later Nov 20, 2025 16:45


A USA TODAY exclusive investigation found thousands of in-custody deaths that could have been easily prevented. USA TODAY Investigative Data Reporter Austin Fast explains what the records reveal about sepsis, medical neglect and the human cost for families left behind. He shares stories from jails and prisons across the country, including people who died waiting for basic care and inmates who feared punishment for asking for help.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Derm Vet Podcast
299. The many faces of pyoderma

The Derm Vet Podcast

Play Episode Listen Later Nov 20, 2025 14:23


Send me a question or story!For how common we see pyoderma in cats and dogs in veterinary practice, the appearance can be variable. A cutaneous bacterial infection can appear as crusting, erythema, scaling, moth-eaten alopecia, epidermal collarette, etc. Differentials can also be varied. Pyoderma can mimic dermatophytosis, demodicosis, pemphigus foliaceus, epitheliotropic lymphoma, etc. Check out this week's episode The Derm Vet podcast! Also, I highly encourage you to check out the YouTube channel to see some clinical images.00:00 – Intro01:20 – Moth-Eaten Alopecia03:18 – Diffuse Alopecia04:21 – Erythema05:27 – Scaling06:40 – Epidermal Collarettes07:57 – Crusting11:15 – Urticaria-like Lesions13:58 – Outro

GamesMyMomFound
Sonic The Hedgehog Vol 4. Infection (Comic 97) - GMMF

GamesMyMomFound

Play Episode Listen Later Nov 20, 2025 51:16


We take a look at Volume 4 of the IDW Sonic and this one starts a new saga, the metal virus saga.  I made comments about this comic being dark so far... but learning very quickly i ain't seen nothing yet.   Come hear us talk about more sonic. Starring Mike Albertin, and Phoebe Stanton.  A Gamer Looks at 40 - https://agamerlooksat40.com/ Phoebe's Twitch - https://www.twitch.tv/theletsplayprincess Phoebe's Podcast - https://nerdsabroadcast.podbean.com/ Zac's Podcast - https://linktr.ee/absolutelythebest Helena - https://linktr.ee/helhathfury Patreon - https://www.patreon.com/GamesMyMomFound Follow us on Facebook. Instagram - gamesmymomfound_ YouTube  - https://youtube.com/c/GamesMyMomFoundPodcast Discord - https://discord.gg/ Sonic The Hedgehog Vol 3. Battle for Angel Island (Comic 95) - GMMF https://gamesmymomfoundpodcast.podbean.com/e/sonic-vol-3-battle-for-angel-island-comic-95-gmmf Sonic The Hedgehog Vol 2. The Fate of Dr Eggman (Comic 90) - GMMF https://gamesmymomfoundpodcast.podbean.com/e/sonic-vol-2-the-fate-of-dr-eggman-comic-90-gmmf Sonic The Hedgehog Vol 1. Fallout (Comic 87) - GMMF https://gamesmymomfoundpodcast.podbean.com/e/sonic-the-hedgehog-vol-1-fallout-comic-87-gmmf Shadow the Hedgehog - GMMF 182 https://gamesmymomfoundpodcast.podbean.com/e/shadow-the-hedgehog-gmmf-182 Sonic Adventure 2 - GMMF 158 https://gamesmymomfoundpodcast.podbean.com/e/sonic-adventure-2-gmmf-158 Knuckles Chaotix (Game/Comic) - GMMF https://gamesmymomfoundpodcast.podbean.com/e/knuckles-chaotix-game-and-comic-gmmf Super Sonic Vs Hyper Knuckles (Comic 15) -  GMMF https://gamesmymomfoundpodcast.podbean.com/e/super-sonic-vs-hyper-knuckles-comic-gmmf Sonic & Knuckles, Sonic 3 - GMMF 18 https://gamesmymomfoundpodcast.podbean.com/e/sonic-knuckles-sonic-3-gmmf-18

Dental Hygiene Basics
110: Why is Infection Control SO Important in Dental Hygiene with Deanna Otts-Whitfield

Dental Hygiene Basics

Play Episode Listen Later Nov 19, 2025 26:22


My guest, Deanna, has an inspiring dental hygiene story starting from her military experience straight out of high school, earning her bachelor's in dental hygiene while working two jobs, and then eventually getting her master's degree! Today, she still practices in the operatory as a dental hygienist while also doing public speaking, CE courses, and writing articles. Infection control is a main topic of discussion in this episode that every RDH and future RDH needs to hear! Timestamps:(00:00) Deanna's RDH Origin Story(03:42) Infection Control in Dental Hygiene(14:16) Obstacles Faced in School(20:04) Expanded Functions within Dental Hygiene (23:48) Being in the Change in Negative Spaces

Tick Boot Camp
Episode 544: How Microbes Like Lyme May Trigger Alzheimer's and Cognitive Decline – Dr. Brian Balin (PCOM)

Tick Boot Camp

Play Episode Listen Later Nov 18, 2025 15:07


Overview This special episode of the Tick Boot Camp Podcast was recorded live at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and PCOM Symposium in collaboration with Pathobiome Perspectives. Hosted by Ali Moresco in partnership with Nikki Schultek, Executive Director of AlzPI, the conversation brings the Tick Boot Camp mission of exploring infection-associated chronic illness (IACI), like Lyme disease and other tick-borne diseases, to the global Alzheimer's and neuroimmunology research community. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen partnered with Ali and Nikki to highlight scientists whose work connects tick-borne illness, microbes, and cognitive decline. This episode features Dr. Brian J. Balin, an internationally recognized neuroscientist whose research has redefined the role of infection in contributing to Alzheimer's disease. Guest Brian J. Balin, PhD Professor of Neuroscience and Neuropathology Director, Center for Chronic Disorders of Aging Philadelphia College of Osteopathic Medicine (PCOM) Dr. Balin directs the Center for Chronic Disorders of Aging and the Adolph and Rose Levis Foundation Laboratory for Alzheimer's Disease Research at PCOM. With a PhD from the University of Maryland School of Medicine and postdoctoral training at the University of Pennsylvania, he has devoted nearly three decades to understanding how chronic infection and inflammation trigger neurodegeneration. His pioneering discovery that the respiratory bacterium Chlamydia pneumoniae infects brain tissue helped establish the Pathogen Hypothesis of Alzheimer's disease. His continuing work explores how tick-borne microbes — including Borrelia burgdorferi (Lyme disease), Bartonella, and Babesia — interact with other pathogens to drive neuroinflammation and cognitive decline. Key Discussion Points How infections such as Chlamydia pneumoniae, Borrelia burgdorferi, Bartonella, and Babesia were detected in Alzheimer's brain tissue. Evidence that microbes can enter the brain via the olfactory pathway or blood-brain barrier, initiating chronic inflammation, amyloid plaque formation, and tau tangle pathology. Findings from Dr. Balin's collaboration with Galaxy Diagnostics and advocate Nicole Bell, revealing polymicrobial infection and even Babesia otocoli — a strain previously believed to infect only deer — in human brain tissue. The use of animal models and 3D human brain organoids to study infection-driven neurodegeneration. Why identifying infection as part of the exposome (environmental insults over a lifetime) is key to developing precision diagnostics and treatments. Future directions: immune-modulating drugs, antimicrobials, and emerging phage therapy. “Infection is part of the exposome — an environmental insult that shapes our health over a lifetime. Recognizing that is key to truly understanding and preventing Alzheimer's disease.” — Dr. Brian J. Balin Why It Matters Dr. Balin's research bridges the worlds of neurology and infectious disease, offering a framework that could revolutionize how Alzheimer's and other neurodegenerative conditions are diagnosed and treated. By recognizing that microbes — including those transmitted by ticks — can initiate neuroinflammation and cognitive decline, his work provides hope for millions living with infection-associated chronic illness. About the Event The interview took place at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and Philadelphia College of Osteopathic Medicine (PCOM) Symposium, October 3, 2025, Ohio University in Dublin, Ohio. The Symposium brought together more than 20 experts exploring how microbes, the microbiome, and the host immune response contribute to neurological and psychiatric diseases such as Alzheimer's, dementia, and PANS/PANDAS. Tick Boot Camp partnered with Ali Moresco and Nikki Schultek to document and share the voices of scientists advancing research on infection-associated chronic illness (IACI). This episode is part of a special series showcasing how pathobiome and microbiome science is changing our understanding of chronic Lyme and neurodegenerative disease. Learn More Learn about the Alzheimer's Pathobiome Initiative (AlzPI) at AlzPI.org. For Dr. Balin's publications and ongoing research, visit the Philadelphia College of Osteopathic Medicine (PCOM) website. Learn more about the Alzheimer's Pathobiome Initiative (AlzPI) Listen to Tick Boot Camp Podcast episodes, including Episode 406: Pathobiome – An Interview with Nikki Schultek and Episode 101: The Young Gun – An Interview with Alex (Ali) Moresco discussed in this interview.

Your Case Is On Hold
Infection and Nonunion in Open Fractures

Your Case Is On Hold

Play Episode Listen Later Nov 18, 2025 34:45


In this episode, Antonia and Andrew discuss the November 19, 2025 issue of JBJS, along with an added dose of entertainment and pop culture. Listen at the gym, on your commute, or whenever your case is on hold!   Link: JBJS website: https://jbjs.org/issue.php   Sponsor: This episode is brought to you by JBJS Clinical Classroom.   Subspecialties: Infection, Orthopaedic Essentials, Trauma, Hip, Knee Chapters (00:00:03) - Your Cases On Hold(00:00:45) - JBJS 10/20/20(00:03:54) - MPO ELISA test for chronic myeloperoxidase(00:11:29) - Chemical Disinfection of Accidental Infections during Orthoped(00:19:06) - Delayed Union and Nonunion Rates and Open Fractures(00:23:45) - Legacy of Open Fracture in the US(00:29:46) - How to prevent 3A in 3A patients(00:30:39) - DARE for early hip, knee infection(00:32:29) - Synovial fluid Mirnas: potential biomarkers in hip and(00:34:09) - Journals Review: The New Issue

Fempower Health
UTI Symptoms But No Infection? What's Really Going On with Your Bladder | Dr. Tamra Lewis

Fempower Health

Play Episode Listen Later Nov 18, 2025 43:22


Honoring Bladder Health Month! Originally Published September 2024. In this episode of Fempower Health, Dr. Tamra Lewis, a board-certified urogynecologist, discusses bladder health, UTI misdiagnoses, and how pelvic floor dysfunction, menopause, and the microbiome impact bladder issues in women. Learn how to advocate for better care and understand your symptoms.Bladder Health Episode SummaryIn this episode of Fempower Health, we sit down with Dr. Tamra Lewis, a board-certified urologist specializing in female pelvic medicine and reconstructive surgery (also known as urogynecology). Dr. Lewis shares her expertise on common bladder health issues affecting women, many of which are frequently misdiagnosed as urinary tract infections (UTIs). We explore the importance of accurate diagnoses, the potential causes of bladder issues, and how women can better advocate for themselves in healthcare settings. This episode is essential listening for women seeking clarity on their bladder health and for clinicians looking to improve patient outcomes.Discussion Points:Why are so many women misdiagnosing themselves with UTIs?What are the common symptoms of bladder problems in women?How can women better describe bladder issues to their healthcare provider?What are the underlying causes of frequent bladder issues in women?How can you tell the difference between a UTI and other bladder problems?Why is it important to have a pelvic exam for bladder issues?How does pelvic floor dysfunction contribute to bladder symptoms?What are the most effective treatments for overactive bladder?How can you prevent recurring urinary tract infections?What role does menopause play in bladder health?What is the impact of the microbiome on bladder health and UTIs?Why should women advocate for more thorough evaluations from their doctors?"It's easier to treat a small problem than to let a small problem become a bigger problem." - Dr. Tamra LewisRelated to this Bladder Health episode:Learn more about Dr. Tamra Lewis and follow her on LinkedIn and InstagramCheck out Fempower Health resources on Pelvic Health

CCO Infectious Disease Podcast
The Ongoing Challenge of Antimicrobial Selection for Bloodstream Infections

CCO Infectious Disease Podcast

Play Episode Listen Later Nov 18, 2025 18:55


Sepsis and bloodstream infections (BSIs) are common and cause millions of deaths each year, with a disproportionate burden in low-income and middle-income countries. Tune in to learn from Jasmine R. Marcelin, MD, FACP, FIDSA, how inadequate antibiotic coverage can be linked to increased mortality and length of stay and how unnecessary broad-spectrum antibiotics can drive antimicrobial resistance. Topics covered include:The worldwide burden of sepsis and BSIsThe ongoing threat of antimicrobial resistanceUS and global health disparities in sepsis, BSI, and antimicrobial resistanceBarriers toward optimizing antibiotic use in BSIsPresenter:Jasmine R. Marcelin, MD, FACP, FIDSAAssociate Professor, Infectious DiseaseAssociate Medical Director, Antimicrobial Stewardship ProgramVice Chair for Belonging and Community Engagement, Department of Internal MedicineCo-Director, Digital Innovation & Social Media Strategy, Division of Infectious DiseasesUniversity of Nebraska Medical CenterOmaha, NebraskaLink to full program and downloadable slides:https://bit.ly/4inoXCxGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

CCO Infectious Disease Podcast
Integration of Genotypic RDT With Rapid Phenotypic AST for Bloodstream Infections

CCO Infectious Disease Podcast

Play Episode Listen Later Nov 18, 2025 17:55


Unnecessary broad-spectrum antibiotics can drive antimicrobial resistance and cause adverse events, whereas inadequate antibiotic coverage is linked to increased mortality and length of stay for patients with bloodstream infections (BSIs). Listen now to learn from Jose Alexander, MD, D(ABMM), CIC, FCCM, SM/MB(ASCP), how to use rapid genotypic and phenotypic antimicrobial susceptibility testing results to inform antibiotic selection for patients with gram-negative BSIs. Topics covered include:Typical patterns of intrinsic antibiotic susceptibility and resistance in EnterobacteralesMechanisms of resistance in gram-negative bacteriaGenotypic rapid diagnostic tests for BSIsResistance markers for earlier targeted therapyRapid phenotypic antimicrobial susceptibility test platforms for blood culturesPresenter:Jose Alexander, MD, D(ABMM), CIC, FCCM, SM/MB(ASCP)Medical and Public Health MicrobiologistMedical and Technical Director of MicrobiologyAdventHealthOrlando, FloridaLink to full program and downloadable slides:https://bit.ly/4inoXCxGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Stories From Women Who Walk
60 Seconds for Motivate Your Monday: Don't Toss Out Your Moldy Bread Just Yet!

Stories From Women Who Walk

Play Episode Listen Later Nov 17, 2025 3:02


Hello to you listening in Sayville, New York!Coming to you from Whidbey Island, Washington this is Stories From Women Who Walk with 60 Seconds for Motivate Your Monday and your host, Diane Wyzga.The other day I was talking with my longtime friends, colleagues and brainstormers, Tania and Leanne, about times when we set out to achieve X but an unintended, better-than-expected Y happened. You know what I mean: the mystery of unintended consequences that turns out to be amazing!Here's one: The Scottish biologist Alexander Fleming  was working on a project on Staphylococcus bacteria at St. Mary's Hospital in London. He took off on vacation leaving behind an uncovered petri dish of bacteria. When he returned he saw a blue-green mold (like what you might find growing on bread exposed to moisture) growing on the dish and that the Staph bacteria were being killed in the area of the mold. Fleming - knowing a good thing when he saw one - identified the mold as the fungus penicillin notatum, and Shazaam! developed penicillin as an antibiotic. Fleming's unintended discovery of penicillin revolutionized the treatment of infections.Click HERE to learn more about the Discovery and Development of Penicillin 1928-1945Now, as to the moldy bread in your kitchen. Yes, penicillin is an antibiotic produced by a fungus called Penicillium notatum. Yes, this fungus is commonly found on moldy bread. Yes, when the fungus grows on bread, it releases penicillin into the surrounding environment.Let me caution you! Not all moldy bread contains penicillin. Moreover, eating moldy bread is a very big “No! No!” as it can contain harmful substances. Having said that think twice before you toss out what might be an unintended answer to a problem.  Question: When did you set out to achieve X but an unintended Y turned out to be what you were looking for?  What happened next?You're always welcome: "Come for the stories - Stay for the magic!" Speaking of magic, I hope you'll subscribe, share a 5-star rating and nice review on your social media or podcast channel of choice, bring your friends and rellies, and join us! You will have wonderful company as we continue to walk our lives together. Be sure to stop by my Quarter Moon Story Arts website, check out the Communication Services, arrange a no-obligation Discovery Call, and stay current with me as "Wyzga on Words" on Substack.Stories From Women Who Walk Production TeamPodcaster: Diane F Wyzga & Quarter Moon Story ArtsMusic: Mer's Waltz from Crossing the Waters by Steve Schuch & Night Heron MusicALL content and image © 2019 to Present Quarter Moon Story Arts. All rights reserved.  If you found this podcast episode helpful, please consider sharing and attributing it to Diane Wyzga of Stories From Women Who Walk podcast with a link back to the original source.

ID:IOTS
124. Moulds that cause chronic subcutaneous infections

ID:IOTS

Play Episode Listen Later Nov 17, 2025 69:02 Transcription Available


SporotrichosisMycetomaChromoblastomycosis...Entomophthorales.Let's face it: you don't know anything about these diseases. That's OK: neither do Callum or Alyssa. That's why we've got a guest! Dr David Chandler is a Consultant Dermatologist, BSMM member and is a member of the Global Mycetoma Working Group. Listen on for everything you need to know about chronic subcutaneous infections caused by moulds!  Support the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

Communicable
Communicable E40: AMR in conflict and crisis zones

Communicable

Play Episode Listen Later Nov 16, 2025 57:24


It's World AMR Awareness Week (WAAW) and we have prepared a special episode in light of that. In this week's Communicable, Navaneeth Narayanan and Thomas Tängdén host Aula Abbara (London, UK), Guido Granata (Rome, Italy) and Tuomas Aro (Helsinki, Finland) to discuss the phenomenon of AMR in conflict and crisis zones. They elaborate on how difficult conditions and austere environments amplify the spread of AMR, drawing on findings from the ongoing conflicts in Ukraine, Gaza, Syria and other regions. Other topics covered include adapting antimicrobial stewardship and infection prevention and control (IPC) practices as well as the need for genuine political will and international collaboration to end conflicts and their exacerbation on AMR.This episode follows the webinar “Beyond the frontlines” organised by ESCMID's AMR Action Subcommittee for WAAW 2025, featuring the same guests, and is available on ESCMID Media. This Communicable episode was peer reviewed by Arjana Zerja of Mother Theresa University Hospital Centre, Tirana, Albania.  Related ESCMID and Communicable mediaESCMID Media, Part 1: Beyond the frontlines - tackling AMR in conflict and crisis zones, webinar Communicable episode 11: Nightmare series, part 2 – how to deal with carbapenemase producers Communicable episode 16: Climate change and infections – effects on clinical practice & sustainabilityResourcesTrainee Association of ESCIMD (TAE) Doctors without Borders (Médecins sans Frontières), Antibiogo, https://www.antibiogo.org/Doctors without Borders (Médecins sans Frontières), Mini-lab, https://fondation.msf.fr/en/projects/mini-lab Further ReadingAbbara A, et al. Unravelling the linkages between conflict and antimicrobial resistance. NPJ Antimicrob Resist. 2025. DOI: 10.1038/s44259-025-00099-yAbbara A, et al. A summary and appraisal of existing evidence of antimicrobial resistance in the Syrian conflict. Int J Infect Dis. 2018. DOI: 10.1016/j.ijid.2018.06.010Abu-Shomar R, et al. Multidrug-resistant Pseudomonas isolated from water at primary health care centers in Gaza, Palestine: a cross-sectional study. IJID Reg. 2025. DOI: 10.1016/j.ijregi.2025.100671Aldbis A, et al. The lived experience of patients with conflict associated injuries whose wounds are affected by antimicrobial resistant organisms: a qualitative study from northwest Syria. Confl Health. 2023. DOI: 10.1186/s13031-023-00501-4Aro T, et al. War on antimicrobial resistance: high carriage rates of multidrug-resistant bacteria among war-injured Ukrainian refugees. Clin Microbiol Infect. 2025. DOI: 10.1016/j.cmi.2025.07.010  Bazzi W, et al. Heavy Metal Toxicity in Armed Conflicts Potentiates AMR in A. baumannii by Selecting for Antibiotic and Heavy Metal Co-resistance Mechanisms. Front Microbiol. 2020. DOI: 10.3389/fmicb.2020.00068 Dewachi O. War Biology and Antimicrobial Resistance: The Case of Gaza, AMR Insights, 2024.Granata G, et al. The impact of armed conflict on the development and global spread of antibiotic resistance: a systematic review. Clin Microbiol Infect. 2024. DOI: 10.1016/j.cmi.2024.03.029 Huang XZ, et al. Molecular analysis of imipenem-resistant Acinetobacter baumannii isolated from US service members wounded in Iraq, 2003-2008. Epidemiol Infect. 2012. DOI: 10.1017/S0950268811002871Hujer KM, et al. Analysis of antibiotic resistance genes in multidrug-resistant Acinetobacter sp. isolates from military and civilian patients treated at the Walter Reed Army Medical Center. Antimicrob Agents Chemother. 2006. DOI: 10.1128/AAC.00778-06Karah N, et al. Teleclinical Microbiology: An Innovative Approach to Providing Web-Enabled Diagnostic Laboratory Services in Syria. Am J Clin Pathol. 2022. DOI: 10.1093/ajcp/aqab160Keen EF 3rd, et al. Evaluation of potential environmental contamination sources for the presence of multidrug-resistant bacteria linked to wound infections in combat casualties. Infect Control Hosp Epidemiol. 2012. DOI: 10.1086/667382Murray CK, et al. Recovery of multidrug-resistant bacteria from combat personnel evacuated from Iraq and Afghanistan at a single military treatment facility. Mil Med. 2009. DOI: 10.7205/milmed-d-03-8008Petersen K, et al. Diversity and clinical impact of Acinetobacter baumannii colonization and infection at a military medical center. J Clin Microbiol. 2011. DOI: 10.1128/JCM.00766-10Scott P, et al. An outbreak of multidrug-resistant Acinetobacter baumannii-calcoaceticus complex infection in the US military health care system associated with military operations in Iraq. Clin Infect Dis. 2007. DOI: 10.1086/518170Sensenig RA, et al. Longitudinal characterization of Acinetobacter baumannii-calcoaceticus complex, Klebsiella pneumoniae, and methicillin-resistant Staphylococcus aureus colonizing and infecting combat casualties. Am J Infect Control. 2012. DOI: 10.1016/j.ajic.2011.03.025World Health Organization. Fourth WHO Global Evidence Review on Health and Migration stresses that equitable access to and appropriate use of antibiotics for refugees and migrants is essential to tackling Antimicrobial Resistance, News, 2022.

Research To Practice | Oncology Videos
Patient Education Resource: Non-Hodgkin Lymphoma — Clinical Experts Address Common Questions Posed by Patients About CAR T-Cell Therapy

Research To Practice | Oncology Videos

Play Episode Listen Later Nov 15, 2025 59:42


Featuring perspectives from Dr Jeremy S Abramson and Dr Manali Kamdar, including the following topics:  Introduction: About This Program (0:00) Overview of Chimeric Antigen Receptor (CAR) T-Cell Therapy (3:10) Potential Treatment Benefits of CAR T-Cell Therapy (10:35) CRS (Cytokine Release Syndrome) and ICANS (Immune Effector Cell-Associated Neurotoxicity Syndrome) (34:32) Finding Information About CAR T; Clinical Trials (42:17) Financial Issues; Risk of Infection (48:11) Coping with Anxiety; Healing and Moving On (55:17) Educational and presenter information

Breakpoints
#126 – What's the Microbiome Gut to Do with It

Breakpoints

Play Episode Listen Later Nov 14, 2025 68:15


Dr. Julie Ann Justo is joined by experts Drs. Krista Gens and Javier A. Villafuerte Gálvez as they dive deep into the gut microbiome and explore the latest therapeutic frontier for C. difficile infections.  From bacteria battles to breakthrough treatments, this one's a must-listen! You can also review the helpful infographic on our website (https://breakpoints-sidp.org/infographics/). This podcast was supported by an unrestricted grant from Nestlé Health Science. References: Helpful review from one of our guest experts: Gens KD, et al. Fecal microbiota transplantation and emerging treatments for Clostridium difficile infection. J Pharm Pract. 2013 Oct;26(5):498-505. doi: 10.1177/0897190013499527. PMID: 23966282. More modern review: Herbin SR, et al. Breaking the Cycle of Recurrent Clostridioides difficile Infections: A Narrative Review Exploring Current and Novel Therapeutic Strategies. J Pharm Pract. 2024 Dec;37(6):1361-1373. doi: 10.1177/08971900241248883. Epub 2024 May 13. PMID: 38739837. Review on designing microbiota based therapies (pre-print only): Ke S, et al. Rational Design of Live Biotherapeutic Products for the Prevention of Clostridioides difficile Infection. 2024 May 02. doi: 10.1101/2024.04.30.591969. [FDA Guidance regarding IND requirements for fecal microbiota transplant](https://www.fda.gov/regulatory-information/search-fda-guidance-documents/enforcement-policy-regarding-investigational-new-drug-requirements-use-fecal-microbiota). 2022 Nov. OpenBiome webpage with resources for hospitals: How to Start an FMT Program. 2025. Peery AF, et al. AGA Clinical Practice Guideline on Fecal Microbiota-Based Therapies for Select Gastrointestinal Diseases. Gastroenterology. 2024 Mar;166(3):409-434. doi: 10.1053/j.gastro.2024.01.008. PMID: 38395525. Johnson S, et al. Clinical Practice Guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults. Clin Infect Dis. 2021 Sep 7;73(5):755-757. doi: 10.1093/cid/ciab718. PMID: 34492699. Henry Ford's experience getting fecal microbiota products for patients: Abene S. Fecal Microbiota Capsules Improve CDI Access Through Specialty Pharmacy Integration. Contagion Live. 2025 Jul 11. An international view on CDI management: Mendo-Lopez R, et al. Best Practices in the Management of Clostridioides difficile Infection in Developing Nations. Trop Med Infect Dis. 2024 Aug 19;9(8):185. doi: 10.3390/tropicalmed9080185. PMID: 39195623. Review on investigational LBP agents: Monday L, et al. Microbiota-Based Live Biotherapeutic Products for Clostridioides Difficile Infection- The Devil is in the Details. Infect Drug Resist. 2024 Feb 15;17:623-639. doi: 10.2147/IDR.S419243. PMID: 38375101. More on quorum sensing: Falà AK, et al. Quorum sensing in human gut and food microbiomes: Significance and potential for therapeutic targeting. Front Microbiol. 2022 Nov 25;13:1002185. doi: 10.3389/fmicb.2022.1002185. PMID: 36504831. Economic impacts of CDI pts: Reilly J, et al. Economic impact of multiple recurrent Clostridioides difficile infection in a community teaching hospital. Infect Control Hosp Epidemiol. 2025 Sep 29:1-3. doi: 10.1017/ice.2025.10295. Epub ahead of print. PMID: 41020576.

Tick Boot Camp
Episode 543: Measuring Brain Fog in Infection-Associated Chronic Illnesses (IACI) - an interview with MIT Researcher Yuri Kim

Tick Boot Camp

Play Episode Listen Later Nov 11, 2025 27:13


Overview This special episode of the Tick Boot Camp Podcast was recorded live at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and PCOM Symposium in collaboration with Pathobiome Perspectives. Hosted by Ali Moresco in partnership with Nikki Schultek, Executive Director of AlzPI, the conversation brings the Tick Boot Camp mission of exploring infection-associated chronic illness (IACI)—like Lyme disease and other tick-borne infections—to the global Alzheimer's and neuroimmunology research community. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen partnered with Ali and Nikki to highlight scientists whose work connects tick-borne illness, microbes, and cognitive decline. This episode features Yuri Kim, RN, Lead Clinical Research Nurse for the MAESTRO Study at the Massachusetts Institute of Technology (MIT), who is leading pioneering work to measure and understand “brain fog” in infection-associated chronic illness. Guest Yuri Kim, RN Lead Clinical Research Nurse, MAESTRO Study Massachusetts Institute of Technology (MIT) Yuri Kim is the Lead Clinical Research Nurse for the MAESTRO Study, the largest clinical study ever conducted at MIT, led by Dr. Michal “Mikki” Caspi Tal, immunologist and immunoengineer at the Massachusetts Institute of Technology. The MAESTRO Study investigates infection-associated chronic illnesses (IACI) such as chronic Lyme disease and aims to objectively measure and understand one of the most debilitating and misunderstood symptoms—brain fog. Yuri has conducted more than 170 participant study visits and integrates patient narratives with advanced neurocognitive, immune, and molecular profiling. Her background includes experience as a trauma ER nurse and clinical research manager on neurodegenerative and rare diseases such as Alzheimer's disease, chronic traumatic encephalopathy (CTE), and amyloidosis. Key Discussion Points How the MAESTRO Study combines subjective patient narratives with objective neurocognitive and biomarker data to better define and measure brain fog. Use of innovative diagnostic tools including EEG (WAVi), RightEye eye-tracking, BrainCheck cognitive testing, and NASA Lean autonomic assessments. Early findings showing slower reaction times and potential correlations between GFAP, NfL, and sCD14 with cognitive symptoms in chronic Lyme and other IACI patients. The role of immune dysregulation, gut permeability, and neuroinflammation in contributing to cognitive impairment. The need for brain fog-specific assessment tools and more research into sex and hormonal differences that may affect neurocognitive outcomes. Why validating and quantifying “invisible symptoms” is vital to patient care and the future of infection-associated chronic illness research. “Brain fog isn't just a symptom—it's a phenomenon interconnected with multiple systems. We're trying to narrow the gap between what patients report and what we can measure.” — Yuri Kim Why It Matters Yuri Kim's work at MIT bridges patient experience and advanced science to address one of the most misunderstood symptoms in infection-associated chronic illness: brain fog. Her research within the MAESTRO Study, under the leadership of Dr. Michal “Mikki” Caspi Tal, is generating objective evidence that validates patient experiences and reveals how chronic infection and immune dysregulation can cause measurable cognitive and physiological changes. By studying infection-associated brain fog in Lyme disease and other chronic conditions, Yuri and the MAESTRO team are helping to shape a new era of diagnostics and care for people living with long-term, infection-driven illness. About the Event The interview took place at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and Philadelphia College of Osteopathic Medicine (PCOM) Symposium, held on October 3, 2025, at Ohio University in Dublin, Ohio. The Symposium brought together more than 20 international experts investigating how microbes, the microbiome, and the host immune response contribute to neurological and psychiatric conditions such as Alzheimer's, dementia, and PANS/PANDAS. Tick Boot Camp partnered with Ali Moresco and Nikki Schultek to capture and share the voices of scientists advancing research on infection-associated chronic illness (IACI). This episode is part of a special Tick Boot Camp series spotlighting how pathobiome and microbiome science are transforming the understanding of chronic Lyme, cognitive dysfunction, and neurodegeneration. Learn More Learn more about the Alzheimer's Pathobiome Initiative (AlzPI) View Yuri Kim's bio on the MIT website Discover more about Dr. Michal “Mikki” Caspi Tal on Tick Boot Camp Listen to Tick Boot Camp Podcast episodes, including Episode 406: Pathobiome – An Interview with Nikki Schultek and Episode 101: The Young Gun – An Interview with Alex (Ali) Moresco discussed in this interview.

This Week in Virology
TWiV 1268: Clinical update with Dr. Daniel Griffin

This Week in Virology

Play Episode Listen Later Nov 8, 2025 51:37


In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses the link between in utero SARS-CoV-2 infection and poor neurodevelopment outcomes, the use of an mRNA vaccine as an anti-cancer therapy, why one should receive the HPV vaccine, asymptomatic H5N1 isolations in humans, and H5N1 on turkey farms, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how two vaccinated physicians became infected with measles, effective of COVID-19 vaccine for children, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, how a specific antibody type may associate with recovery from long COVID, if use of a probiotic is helpful to treat mild COVID-19, if vaccination helps prevent long in adolescents and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Neurodevelopmental Outcomes of 3-Year-Old Children Exposed to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Utero (Obstetrics & Gynecology) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1267: A cancer vaccine and an mpox treatment (microbeTV: TWiV1267) Cancers Caused by HPV (CDC: Human papillomavirus (HPV)) Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection (Journal of National Cancer Institute) Impact of Vaccinating Adult Women Who Are HPV-Positive or with Confirmed Cervical SIL with the 9-Valent Vaccine (Viruses) ACIP Shared Clinical Decision-Making Recommendations (CDC: Advisory Committee on Immunization Practices (ACIP)) HPV Vaccination Recommendation (CDC: Vaccines & Immunizations) Asymptomatic Human Infections With Avian Influenza A(H5N1) Virus Confirmed by Molecular and Serologic Testing (JAMA: OPEN Network) Review: Human H5N1 avian flu cases can be asymptomatic, and the virus likely spreads among people (CIDRAP) Avian flu strikes turkey farms in Dakotas, large egg facility in California (CIDRAP) Another Doctor at Ichilov Contracts Measles After Treating Unvaccinated Child (gov.il) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles (CDC Measles (Rubeola)) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Vascular and inflammatory diseases after COVID-19 infection and vaccination in children and young people in England (LANCET: Child & Adolescent Health) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Real-World Effectiveness of Nirmatrelvir-Ritonavir in Preventing Coronavirus Disease 2019–Associated Hospitalization (CID) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID SARS-CoV-2 spike-specific IgG4 class switching associates with clinical recovery in Long COVID (Journal of Infection) Efficacy of Lactococcus lactis Strain Plasma in Patients with Mild COVID-19 (Infectious Diseases and Therapy) Preventive effect of vaccination on long COVID in adolescents with SARS-CoV-2 infection (Vaccine) Reaching out to US house representative Letters read on TWiV 1268 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

The Derm Vet Podcast
297. Three cases that spooked me!

The Derm Vet Podcast

Play Episode Listen Later Nov 6, 2025 21:02


Send me a question or story!Even as a specialist, I still get cases that surprise me or change appearances. It can leave me doubting what the next step is. But, if you take a breath, it is amazing what can happen when you figure them out. Check out three cases that recently threw me for a loop.1. A dog with weird paw pad ulcers2. A cat with an ulcerated nasal planum3. A service dog with non-pruritic alopecia and scalingHint: If you check out the YouTube channel, there are a lot of clinical photos!00:00  Intro02:14  Case Number 1: Veni08:02  Case Number 2: Gadget14:42  Case Number 3: Bruno19:19  Outro

JJ Virgin Lifestyle Show
Toxins, Parasites and Infections: Why Your Hormones Are Out of Whack with Dr. Jaban Moore

JJ Virgin Lifestyle Show

Play Episode Listen Later Nov 5, 2025 59:57


What are the most common chronic infections that women may be struggling with, and what can be done about them? In this episode, I'm joined by Dr. Jaban Moore. We dig into how parasites, mold, and heavy metals silently disrupt your hormones, energy, and brain health—and what real detoxing actually looks like. You'll learn why annual testing isn't enough, how to build a toxin-resistant lifestyle, and why nervous system regulation is just as important as any supplement. Dr. Moore is a former athlete turned functional medicine doctor who helps clients overcome chronic infections, toxic overload, and burnout. He has made it his mission to help others heal naturally and feel strong again through detoxing, gut repair, and nervous system balance. What you'll learn: (01:27) How Dr. Moore's personal battle with Lyme disease led him into functional medicine. (06:32) Why toxins and infections can cause early menopause symptoms. (09:11) How parasites, viruses, and mold spread. (14:44) How the organic acid test reveals your energy, detox, and microbiome health. (19:32) The surprising prevalence of parasites and how they mimic common GI and hormonal symptoms. (33:16) How to perform a parasite cleanse safely using herbal and detox support. (38:50) Why detoxing is a lifestyle, not a quick fix. Love the podcast? Here's what to do: Subscribe to the podcast. Leave a review. Text a screenshot to me at 813-565-2627 and wait for a personal reply because your voice is so important to me. Want to listen to the show completely ad-free? Go to http://subscribetojj.com Click “TRY FREE” and start your ad-free journey today! When you're ready, enjoy the VIP experience for just $4.99 per month or $49.99 per year (save 17%!) Full show notes (including all links mentioned): https://jjvirgin.com/jaban Learn more about your ad choices. Visit megaphone.fm/adchoices

PediaCast
RSV Infections in Babies: Symptoms, Treatment, Prevention - PediaCast 592

PediaCast

Play Episode Listen Later Nov 4, 2025 46:29


Dr Bill Long and Dr Pablo Sanchez visit the studio as we consider RSV infections in babies and young children. We explore the seasonality of these infections, along with their symptoms, treatment, and prevention. We hope you can join us!

Behind The Knife: The Surgery Podcast
Clinical Challenges in Hernia Surgery: Mesh Infections - How to Treat and What to Consider

Behind The Knife: The Surgery Podcast

Play Episode Listen Later Nov 3, 2025 22:17


Mesh infections are dreaded complications in hernia repair. This episode highlights relevant mesh properties, pathogens, and management strategies so you can tackle the next mesh infection with confidence! Hosts: Dr. Maggie Bosley - @MBosleyMD Dr. Sean Orenstein - @OrensteinSean Dr. Amber Sandoval Dr. Peter Ferrin Institution: Oregon Health & Science University Learning Objectives - Compare the long-term weight loss and diabetes remission rates of Gastric Bypass vs. Sleeve Gastrectomy. - Identify the appropriate revision options (Bypass vs. Sadie) for a patient with a failed sleeve based on the reason for failure (reflux vs. weight regain). - Recognize that all bariatric operations are superior to untreated obesity, making patient selection paramount. Episode Sponsor Disclosures: Visit goremedical.com/btk to learn more about GORE® ENFORM Biomaterial. Refer to Instructions for Use at eifu.goremedical.com for a complete description of all applicable indications, warnings, precautions and contraindications for the markets where this product is available. Rx only Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listen Behind the Knife Premium: General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-review Trauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlas Dominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkship Dominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotation Vascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-review Colorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-review Surgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-review Cardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-review Download our App: Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049 Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

Mock and Daisy's Common Sense Cast
Heritage's Surprise Defense of Tucker, Kamala Admits Biden Feud, & The Fuentes Infection

Mock and Daisy's Common Sense Cast

Play Episode Listen Later Oct 31, 2025 65:08


In today's packed episode, we're covering everything from Kamala Harris dropping F-bombs and roasting Biden, to Jasmine Crockett's viral outburst, to Democrats crumbling under pressure over the government shutdown. Trump trolls the media mid-flight, JD Vance takes heat for a hug, and even the Heritage Foundation steps in to defend Tucker Carlson.Plus, we get Kamala's most unhinged interview moments yet — handlers, ballroom complaints, and all. Add in Newsom's fake charm, United Airlines calling out Democrats, and Nick Fuentes trying to drag the conservative movement down a dark hole.SUPPORT OUR SPONSORS TO SUPPORT OUR SHOW!Whatever fall throws at you, make sure you're prepared—visit https://ReadyWise.com and use code CHICKS10 for 10% off your order today!For free and unbiased Medicare help, call 442-3-CHICKS (442-324-4257) to speak with a Chapter advisor for guidance from experts who know Medicare inside and out.Give your furry friend the gift of healthy, happy skin this season—save 15% on all Coat Defense products at https://CoatDefense.com with code CHICKS at checkout!Add Lean to your diet and exercise routine to lose meaningful weight at a healthy pace and keep it off.  Get 20% off when you enter code CHICKS at https://TakeLean.comVISIT OUR WEBSITE DAILY!  https://chicksonright.comSUBSCRIBE TO OUR PODCAST: https://link.chtbl.com/BtHbvS8C?sid=youtubeJOIN OUR SUPPORTER COMMUNITY ON LOCALS:  https://chicksontheright.locals.com/JOIN OUR SUPER DOUBLE AWESOME SECRET BUT NOT SECRET EXCLUSIVE GROUP: https://www.facebook.com/groups/388315619071775Subscribe to our email list: https://politics.chicksonright.com/subscribe/GET OUR BOOK! https://www.amazon.com/dp/B08H5D3CF1/ref=cm_sw_r_cp_api_fabc_JdhQFbZ363CAYVenmo: @chicksonrightPaypal: https://www.paypal.me/chicksonrightGet exclusive Chicks merch here:  https://www.etsy.com/shop/InRealLifeCreations?ref=seller-platform-mcnav§ion_id=50399398Even more Merch: https://shop.spreadshirt.com/chicksonright/ Thank you for the Superchats!  Watch live to donate and be recognized! Facebook:  Chicks on the RightFacebook Group:  Chicks on the RightTwitter, IG, Parler, Rumble:   @chicksonright