Podcasts about Infection

Invasion of an organism's body tissues by disease-causing agents

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Best podcasts about Infection

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Latest podcast episodes about Infection

Agriculture Today
2086 - Whitetail Deer Impacts...Fall Infections of Rust in Wheat

Agriculture Today

Play Episode Listen Later Dec 23, 2025 28:01


Fins, Fur and Feathers: Pros and Cons of Whitetail Deer Rust Infections in Wheat Matching Finances and Production Data   00:01:05 – Fins, Fur and Feathers: Pros and Cons of Whitetail Deer: The show begins with part of a Fins, Fur and Feathers podcast episode where Drew Ricketts and Joe Gerken talk about balancing the positive and negatives of whitetail deer. Fins, Fur, and Feathers wildlife.k-state.edu   00:12:05 – Rust Infections in Wheat: Kelsey Andersen Onofre, K-State wheat pathologist, and Logan Simon, K-State Extension agronomist, keep the show moving as they discuss rust in wheat and other challenges they expect the crop to encounter this season.  Fall Infections of Rusts in Kansas Wheat   00:23:05 – Matching Finances and Production Data: K-State dairy specialist Mike Brouk ends the show explaining matching data from the production site with the financial output of the farm to measure financial success.       Send comments, questions or requests for copies of past programs to ksrenews@ksu.edu.   Agriculture Today is a daily program featuring Kansas State University agricultural specialists and other experts examining ag issues facing Kansas and the nation. It is hosted by Shelby Varner and distributed to radio stations throughout Kansas and as a daily podcast.   K‑State Extension is a short name for the Kansas State University Agricultural Experiment Service, a program designed to generate and distribute useful knowledge for the well‑being of Kansans. Supported by county, state, federal and private funds, the program has county Extension offices statewide. Its headquarters is on the K‑State campus in Manhattan. For more information, visit www.ksre.ksu.edu. K-State Extension is an equal opportunity provider and employer.

The Poisoner's Almanac
WWII Nazi Experiments PT 4: Poisons, Infection, & Chemical Weapons

The Poisoner's Almanac

Play Episode Listen Later Dec 21, 2025 69:34


Hello Poison Friends! Let's talk poison experiments done by Nazi's during WWII.Alkaloid poisons, corrosive poisons like phenol, and flammable substances used in incendiary weapons like phosphorus. Mustard and Phosgene gas were also experimented with as were various methods of euthanasia.Many of those experimented on them died or were left with permanent injuries. We have excerpts from the testimonies given by some survivors and reports and letters sent between Nazi doctors that tell us what happened. Trigger warning for this episode as there are many horrific details among the testimonies and reports. Thank you to all of our listeners and supporters! Please feel free to leave a comment or send us a DM for any questions or suggestionsPatreon:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠patreon.com/thepoisonersalmanac⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Merch-⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://poisonersalmanac.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The Poisoner's Almanac IG-⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/poisoners_almanac?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw==⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Poisoner's Almanac TT-⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@poisonersalmanacp?_t=ZT-8wdYQyXhKbm&_r=1⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Adam-⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@studiesshow?is_from_webapp=1&sender_device=pc⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

CoROM cast. Wilderness, Austere, Remote and Resource-limited Medicine.
174-Austere Burns Management from the JTS CPG

CoROM cast. Wilderness, Austere, Remote and Resource-limited Medicine.

Play Episode Listen Later Dec 19, 2025 49:18


This week, Aebhric O'Kelly, Bill Vasios, and Rhod Jordan will host an open discussion on managing austere burn patients, covering airway management, fluid resuscitation, infection control, and pain management. The speakers emphasise the complexity of burn cases and the importance of accurate assessment and treatment protocols. They also highlight the need for effective communication and patient involvement in care, as well as the use of innovative techniques like topical morphine for pain management.TakeawaysBurns are incredibly complicated, but they're complex patients.Managing an individual patient's airway has to be factored in.You want to protect and secure the airway and avoid obstructions.The goal is to achieve maximal accuracy in fluid resuscitation.You can infuse that fluid rectally if you don't have IV fluids.Prophylactic antibiotics are not indicated in burn patients.Topical morphine works really, really well for pain management.Involving the patient in their care has a positive effect.Infection control is the means of preventing infection.Burn management is more art than science.Chapters00:00 Introduction to Burns Management03:08 Airway Management in Burn Patients05:52 Assessing Burn Size and Fluid Resuscitation09:00 Fluid Administration Techniques11:38 Oral vs IV Resuscitation14:53 Monitoring and Adjusting Treatment17:36 Dynamic Management of Burn Patients25:18 Vital Signs Monitoring in Critical Care28:01 Continuous Assessment and Patient Management32:07 Patient Involvement in Vital Signs Monitoring35:10 Urine Output and Fluid Resuscitation41:33 Infection Control in Burn Management48:20 Pain Management Strategies in Burns

The Derm Vet Podcast
303. When the allergy drugs "quit working"

The Derm Vet Podcast

Play Episode Listen Later Dec 18, 2025 12:42


Send me a question or story!It is very common for clients to present their pet to the veterinarian complaining that an allergy medication that used to work is no longer effective. Before changing therapies, it is important to consider four different things.1. Rule out simple mistakes like missed flea prevention, diet change, etc.2. Identify infection3. Progression of allergies4. It is no longer just allergiesLearn more details on this week's episode of The Derm Vet podcast!Timestamps00:00 Intro01:20 Looking for Simple Causes03:47 Identify Infections06:10 Allergy Progression08:30 When It Isn't Just Allergies10:22 Overview12:05 Outro

Obstetrics & Gynecology: Editor's Picks and Perspectives
January 2026: Updates in Infectious Diseases in Pregnancy

Obstetrics & Gynecology: Editor's Picks and Perspectives

Play Episode Listen Later Dec 18, 2025 27:33


A Podcast from Obstetrics & Gynecology highlighting the latest research and practice updates in the field. This episode features interviews with Dr. Naima Joseph, author of "Measles in Pregnancy: Clinical Considerations and Challenges," and Dr. Andrea G. Edlow, author of "Neurodevelopmental Outcomes of 3-Year-Old Children Exposed to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Utero."

CCO Infectious Disease Podcast
Decera Clinical Education Independent Conference Coverage of IDWeek and EACS 2025: HIV Update Podcast

CCO Infectious Disease Podcast

Play Episode Listen Later Dec 18, 2025 36:47


Tune into this podcast to revisit discussions led by global experts, Karine Lacombe, MD, PhD, and Chloe Orkin, MBChB, FRCP, MD, featuring the latest updates on HIV treatment and prevention from the 2025 IDWeek and EACS conferences.Topics covered include:Real-world safety and efficacy of long-acting ARTART switch: preferences, treatment satisfaction, changes in weight and metabolic parameters, and HBV reactivation riskInvestigational therapiesUpdates on long-acting PrEP: persistence, use in people with substance use disorder, and coadministration with gender-affirming hormone therapyHIV and STI screening with PrEPSTI prevention To download the accompanying slides, visit the program page for this episode:https://bit.ly/3MGvegMPresenters:Karine Lacombe, MD, PhDProfessor of MedicineSorbonne UniversityHead of Infectious Diseases UnitSt Antoine Hospital, AP-HPParis, FranceChloe Orkin, MBChB, FRCP, MDProfessor of Infection and InequitiesDean for Healthcare TransformationQueen Mary University of LondonFaculty of Medicine and DentistryHonorary Consultant PhysicianBarts Health NHS TrustLondon, United KingdomGet access to all of our new episodes by subscribing to the Decera Clinical Education Infectious Diseases Podcast on Apple Podcasts, YouTube Music, or Spotify. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Stoicism: Philosophy as a Way of Life Podcast
The Rescuer Trap: The Skeptic's Guide to Autonomy

Stoicism: Philosophy as a Way of Life Podcast

Play Episode Listen Later Dec 17, 2025 67:48


This episode features guest hosts Dr. Scott Waltman and Kasey Pierce, authors of the forthcoming book The Rescuer Trap. Is it a gut Instinct or gut Infection? This week, we talk to Massimo Pigliucci about why the brain is essentially a ‘b******t' machine and how to stop being a doormat by embracing ancient doubt. By the end of the episode, Pigliucci leaves Kasey and Scott grappling with the fundamental question: Whose Socrates is it anyway? (the Stoics' or the Skeptics'?) Are you the fixer, the over-giver, the emotional first responder for everyone but yourself? Welcome to The Rescuer Trap. We playfully own the labels “Parentified and Codependent” to make a point: these are not identities, but learned behaviors.Stoicism: Philosophy as a Way of Life is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.And what can be learned can be unlearned. Hosts Dr. Scott Waltman and Kasey Pierce use Stoic philosophy and CBT to give you the tools to break the cycle and reclaim your autonomy. Your escape from the trap starts here. Based on the forthcoming book, The Rescuer Trap (New Harbinger).Thanks for reading Stoicism: Philosophy as a Way of Life! This post is public so feel free to share it. Get full access to Stoicism: Philosophy as a Way of Life at donaldrobertson.substack.com/subscribe

Gastroenterology Learning Network
Gut Check: Maria Vazquez-Roque, MD, on C difficile Infection

Gastroenterology Learning Network

Play Episode Listen Later Dec 17, 2025 29:19


Gut Check: Maria Vazquez-Roque, MD, on C difficile Infection by Gastroenterology Learning Network

Tick Boot Camp
Episode 548: When Infections Leave a Mark: How the Immune System Remembers and Shapes Alzheimer's | Dr. Betsy Bradshaw

Tick Boot Camp

Play Episode Listen Later Dec 16, 2025 18:28


Overview This special episode of the [Tick Boot Camp Podcast](https://tickbootcamp.com/podcast/) was recorded live at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and PCOM Symposium in collaboration with Pathobiome Perspectives. Hosted by Ali Moresco in partnership with Nikki Schultek, Executive Director of AlzPI, the conversation continues the Tick Boot Camp mission of exploring infection-associated chronic illness (IACI)—including Lyme disease and other tick-borne infections—within the global Alzheimer's and neuroimmunology research community. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen partnered with Ali and Nikki to highlight leading scientists connecting microbes, immune dysregulation, and neurodegenerative disease. This episode features Dr. Elizabeth “Betsy” Bradshaw, Assistant Professor of Neurology at Columbia University Irving Medical Center, whose research investigates how past infections leave lasting imprints on the brain's immune system and influence the development of Alzheimer's disease. Guest Elizabeth M. Bradshaw, PhD Assistant Professor of Neurology, Columbia University Irving Medical Center Principal Investigator, Bradshaw Laboratory – Neuroimmunology and Genetics of Alzheimer's Dr. Bradshaw's laboratory focuses on the immune system's role in neurodegeneration, particularly how infection and inflammation alter brain immunity and predispose individuals to conditions like Alzheimer's disease. Her work builds on large-scale genome-wide association studies (GWAS) that identified immune-related genetic variants linked to Alzheimer's susceptibility, suggesting that subtle changes in immune function—not just neuronal factors—may underlie disease onset. Her team is exploring how pathogens such as HSV-1 (Herpes Simplex Virus Type 1) interact with the brain's immune cells, known as microglia, and how these infections can “reprogram” immune responses long after the pathogen is cleared. Key Discussion Points Dr. Bradshaw explains how her research bridges genetics, immunology, and infectious disease to better understand Alzheimer's. Through GWAS data, her team found that many of the genes linked to Alzheimer's risk involve immune pathways rather than neuronal signaling. This discovery redirected the field's attention toward how immune cells respond to pathogens and environmental stressors across a lifetime. Using human-derived microglia-like cells created from blood monocytes, her team observes how infections reshape immune cell metabolism and memory. By infecting these microglia-like cells with Alzheimer's-associated pathogens like HSV-1, they study how genetic background and infection history determine immune cell behavior. The findings suggest that past infections may epigenetically and metabolically train microglia—changing how they respond to aging, stress, and amyloid buildup. Even when the infection has resolved, these “reprogrammed” immune cells can remain altered for decades, silently increasing the brain's vulnerability to neurodegeneration. Dr. Bradshaw emphasizes that understanding how infections rewire the brain's immune landscape could transform early intervention strategies. Identifying combinations of genetic risk factors and pathogen exposures may enable targeted prevention or immune-modulating treatments long before symptoms appear. “Microglia remember. Even after the pathogen is gone, they carry its imprint—responding differently decades later when the brain faces new challenges.” — Dr. Elizabeth Bradshaw Why It Matters Dr. Bradshaw's work reframes Alzheimer's disease as a neuroimmune condition shaped by infection and host genetics. Her research highlights how microbial exposures, immune history, and inflammation converge to influence cognitive decline. By integrating infection biology with genetics and immunology, her team is redefining how scientists and clinicians view the root causes of Alzheimer's and other neurodegenerative diseases. This work strengthens the growing case that the immune system's “memory” of infection may be one of the most important and overlooked factors in brain health and aging. About the Event This interview was recorded at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and Philadelphia College of Osteopathic Medicine (PCOM) Symposium, held October 3, 2025, at Ohio University in Dublin, Ohio. The event brought together more than 20 leading researchers exploring how microbes, the microbiome, and immune dysregulation contribute to Alzheimer's, dementia, and infection-associated chronic illness (IACI). Tick Boot Camp partnered with Ali Moresco and Nikki Schultek to share these conversations and connect chronic Lyme, infection, and neurodegenerative research communities. Learn More Learn more about the Alzheimer's Pathobiome Initiative (AlzPI) Listen to Tick Boot Camp Podcast episodes, including Episode 406: Pathobiome – An Interview with Nikki Schultek and Episode 101: The Young Gun – An Interview with Alex (Ali) Moresco discussed in this interview.

The OTA Podcast
In the Booth 2025: Nine Months of Fluoxetine Aides in the Reduction of Negative Psychiatric Symptomology / PO vs IV Antibiotics for Fracture Related Infections

The OTA Podcast

Play Episode Listen Later Dec 16, 2025 12:12


Host Dr. Malcolm DeBaun chats with paper author Dr. Jennifer Hagen about the findings of their research: "Nine Months of Fluoxetine Aides in the Reduction of Negative Psychiatric Symptomology Following a Traumatic Musculoskeletal Injury" in the first part of the episode. In the second part, Dr. DeBaun discusses the findings with paper author Dr. Nathaniel E. Schaffer from the paper entitle: "PO vs IV Antibiotics for Fracture Related Infections: Bayesian Analysis." Live from the 2025 OTA Annual Meeting. For additional educational resources visit OTA.org

Gresham College Lectures
Why Do We Laugh? - Robin May

Gresham College Lectures

Play Episode Listen Later Dec 16, 2025 38:12


Laughter is an incredibly powerful and yet mysterious emotion. We laugh with delight, but also surprise. We laugh at jokes, but also at embarrassment. Why? What subconscious signal is laughter intended to display? Why do we laugh when someone tickles us and what should we make of the fact that rodents do it too? And why is it that people's sense of humour differs wildly and yet some drugs can send us all into fits of the giggles, even if there is nothing to laugh at?This lecture was recorded by Robin May on the 12th of November 2025 at Bernard's Inn Hall, LondonProfessor of Infectious Disease at the University of Birmingham, and (interim) Chief Scientist at the UK Health Security Agency, Robin May was appointed Gresham Professor of Physic in May 2022. Between July 2020 and September 2025 he served as Chief Scientific Adviser at the Food Standards Agency (FSA). Professor May's early training was in Plant Sciences at the University of Oxford, followed by a PhD on mammalian cell biology at University College London and the University of Birmingham. After postdoctoral research on gene silencing at the Hubrecht Laboratory, The Netherlands, he returned to the UK in 2005 to establish a research program on human infectious diseases. He was Director of the Institute of Microbiology and Infection at the University of Birmingham from 2017-2020. Professor May continues his work on Infectious Disease at the University of Birmingham. A Fellow of the Academy of Medical Sciences, Wolfson Royal Society Research Merit Fellow and Fellow of the American Academy of Microbiology, Professor May specialises in research into human infectious diseases, with a particular focus on how pathogens survive and replicate within host organisms.As the FSA's Chief Scientific Adviser, Professor May provides expert scientific advice to the UK government and plays a critical role in helping to understand how scientific developments will shape the work of the FSA, as well as the strategic implications of any possible changes.The transcript of the lecture is available from the Gresham College website: https://www.gresham.ac.uk/watch-now/why-laughGresham College has offered free public lectures for over 400 years, thanks to the generosity of our supporters. There are currently over 2,500 lectures free to access. We believe that everyone should have the opportunity to learn from some of the greatest minds. To support Gresham College's mission, please consider making a donation: https://www.gresham.ac.uk/get-involved/support-us/make-donation/donate-today Website:  https://gresham.ac.ukX: https://x.com/GreshamCollegeFacebook: https://facebook.com/greshamcollegeInstagram: https://instagram.com/greshamcollegeBluesky: https://bsky.app/profile/greshamcollege.bsky.social TikTok: https://www.tiktok.com/@greshamcollegeSupport Us: https://www.gresham.ac.uk/get-involved/support-us/make-donation/donate-todaySupport the show

JACC Speciality Journals
Brief Introduction - Temporal Trends in Utilization of Transvenous Lead Extractions Among Cardiac Implantable Electronic Device Infections | JACC: Asia

JACC Speciality Journals

Play Episode Listen Later Dec 16, 2025 1:27


HAINS Talk
Journal Club Folge 50 (KW 51): Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections

HAINS Talk

Play Episode Listen Later Dec 16, 2025 13:06


Send us a textHAINS Talk ist nach längerer (Zwangs-)Pause wieder zurück:BALANCE Investigators, for the Canadian Critical Care Trials Group, the Association of Medical Microbiology and Infectious Disease Canada Clinical Research Network, the Australian and New Zealand Intensive Care Society Clinical Trials Group, and the Australasian Society for Infectious Diseases Clinical Research Network, Daneman, N. et al. (2025). Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections. The New England journal of medicine, 392(11), 1065–1078. https://doi.org/10.1056/NEJMoa2404991Mit im Studio: Dr. Anna Hafner, wissenschaftliche Mitarbeiterin der Klinik für Anästhesiologie

Regenerative Health with Max Gulhane, MD
95. Critical role of the Vitamin D system in Infection and Immunity | Prof Sunil Wimalawansa

Regenerative Health with Max Gulhane, MD

Play Episode Listen Later Dec 14, 2025 104:50 Transcription Available


Expert physician researcher Sunil Wimalawansa explains why Vitamin D plays a critical role in immune system function, the physiology various forms of vitamin D and how to ensure you keep a level compatible with optimal health.Dr Sunil J. Wimalawansa, MD, PhD is a globally respected clinician-scientist, educator, over three decades of leadership in endocrinology, osteoporosis, metabolic bone disease, and nutrition. He served as professor and chief of endocrinology at leading U.S. medical institutions, including the Robert Wood Johnson Medical School/Rutgers University.CONSULT DR MAXInitial consult - https://www.drmaxgulhane.com/offers/5jfDvLyH/checkoutSUPPORT MY WORK

Communicable
Communicable E42: Should doctors stay at X (Twitter) or leave it?

Communicable

Play Episode Listen Later Dec 14, 2025 65:03


During the COVID-19 pandemic with lockdown mandates and social distancing, doctors, researchers, and the public were able to find refuge and community online; for the infectious disease community, it was on the social media platform Twitter, and more specifically under the widely used hashtag, #IDTwitter. Under new ownership from 2022, however, Twitter's name and brand changed to what we now know as X, and “the heyday of #IDTwitter is long since gone”. In this special episode of Communicable, Angela Huttner and Marc Bonten invite doctors and science communicators, Neil Stone (London, UK), Ilan Schwartz (Durham, USA), and Tara Smith (Kent, USA) to debate whether we should stay on X or leave it for alternatives.This episode is a follow-up from Stone and Schwartz's commentary [1] and Smith's response letter [2] addressing the same topic published in CMI Communications. The views expressed by the panelists are their own and do not represent the positions of their affiliated institutions or ESCMID. This episode was not peer reviewed.ResourcesYou can follow all participants of this episode on Bluesky: @drneilstone.bsky.social, @germhuntermd.bsky.social, @aetiology.bsky.social, @marcbonten.bsky.social, @angelahuttner.bsky.social, and Stone on X: @DrNeilStone.ReferencesStone NRH and Schwartz IS. Joining the X-odus: Contrasting perspectives on whether infection specialists should leave X (formerly Twitter). CMI Comms 2025. DOI: 10.1016/j.cmicom.2025.105140Smith TC. Twitter remains a haven of harassment. CMI Comms 2025. DOI: 10.1016/j.cmicom.2025.105144Further readingBiever, C. Bluesky's science takeover: 70% of Nature poll respondents use platform. Nature News 2025. PEW Research Center. How Do Americans View Childhood Vaccines, Vaccine Research and Policy? https://www.pewresearch.org/science/2025/11/18/how-do-americans-view-childhood-vaccines-vaccine-research-and-policy/   NBC News. X's new location labels unmask users. Insiders say the idea was rejected for years. https://www.nbcnews.com/tech/elon-musk/x-user-location-feature-country-elon-musk-new-rcna245620

The Robert Scott Bell Show
Jonathan Emord, Free Speech Battles, FDA Overreach, Health Freedom, Long Covid Infections, Sleep Apnea - The RSB Show 12-11-25

The Robert Scott Bell Show

Play Episode Listen Later Dec 12, 2025 119:34


TODAY ON THE ROBERT SCOTT BELL SHOW: Jonathan Emord, Free Speech Battles, FDA Overreach, Health Freedom, RFK Jr Attacked, Hidden Long Covid Infections, Mineral Deficiency Mysteries, Sleep Apnea Survival, EPA's MAHA Plan and MORE! https://robertscottbell.com/jonathan-emord-free-speech-battles-fda-overreach-health-freedom-rfk-jr-attacked-hidden-long-covid-infections-mineral-deficiency-mysteries-sleep-apnea-survival-epas-maha-plan-and-more/https://boxcast.tv/view/jonathan-emord-free-speech-battles-fda-overreach-health-freedom-long-covid-infections-sleep-apnea---the-rsb-show-12-11-25-ccwqooejabvg0yfc2bvs Purpose and Character The use of copyrighted material on the website is for non-commercial, educational purposes, and is intended to provide benefit to the public through information, critique, teaching, scholarship, or research. Nature of Copyrighted Material Weensure that the copyrighted material used is for supplementary and illustrative purposes and that it contributes significantly to the user's understanding of the content in a non-detrimental way to the commercial value of the original content. Amount and Substantiality Our website uses only the necessary amount of copyrighted material to achieve the intended purpose and does not substitute for the original market of the copyrighted works. Effect on Market Value The use of copyrighted material on our website does not in any way diminish or affect the market value of the original work. We believe that our use constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the U.S. Copyright Law. If you believe that any content on the website violates your copyright, please contact us providing the necessary information, and we will take appropriate action to address your concern.

Estelle Midi
La consultation gratuite : Comment traiter et prévenir les infections urinaires ? - 12/12

Estelle Midi

Play Episode Listen Later Dec 12, 2025 6:23


Chaque jour dans Estelle Midi, le médecin urgentiste Aurel Guedj vous partage des infos et conseils sur votre santé.

The People's Pharmacy
Show 1455: Common Culprits: How Infections Trigger Chronic Diseases

The People's Pharmacy

Play Episode Listen Later Dec 11, 2025 65:54


When doctors talk about infections, they are usually referring to acute situations in which the immune system gets overwhelmed by a virus such as influenza or chickenpox. Infections also result from the interaction of bacteria with the immune system, as in the case of pneumonia or sepsis. These can be crises, but they are relatively […]

Six O'Clock News
Surging flu infections leave NHS England facing 'worst case scenario'.

Six O'Clock News

Play Episode Listen Later Dec 11, 2025 30:25


Last week, there was an average of 2660 people a day with flu in England's hospital beds, a 55% increase on the week before. A more virulent, mutated strain is being blamed for the spike in cases. Also: President Zelensky insists Ukraine must have a vote before ceding any territory to Russia. And: ticket prices for next year's football World Cup are revealed.

Research To Practice | Oncology Videos
CAR T-Cell Therapy for Non-Hodgkin Lymphoma | Cancer Q&A — Discussing Common Questions Posed by Patients

Research To Practice | Oncology Videos

Play Episode Listen Later Dec 11, 2025 58:31


Featuring perspectives from Dr Jeremy S Abramson and Dr Loretta J Nastoupil, including the following topics: Overview of Chimeric Antigen Receptor (CAR) T-Cell Therapy (0:00) Potential Treatment Benefits of CAR T-Cell Therapy (13:31) Cytokine Release Syndrome and Immune Effector Cell-Associated Neurotoxicity Syndrome (28:13) Finding Information About CAR T-Cell Therapy; Clinical Trials (36:28) Financial Issues; Risk of Infection (42:02) Coping with Anxiety; Healing and Moving On (53:27) CME information and select publications

Tick Boot Camp
Episode 602: How Bartonella Hijacks the Brain's Immune System: Linking Infection and Neurodegeneration – Dr. Janice Bush

Tick Boot Camp

Play Episode Listen Later Dec 9, 2025 19:35


Overview This special episode of the Tick Boot Camp Podcast was recorded live at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and PCOM Symposium in collaboration with Pathobiome Perspectives. Hosted by Ali Moresco in partnership with Nikki Schultek, Executive Director of AlzPI, this series expands the Tick Boot Camp mission of exploring infection-associated chronic illness (IACI)—including Lyme and other tick-borne infections—to the global Alzheimer's and neuroimmunology research community. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen partnered with Ali and Nikki to showcase scientists exploring the microbial and immune mechanisms behind neurodegeneration. This episode features Dr. Janice Bush, a PhD candidate at North Carolina State University's College of Veterinary Medicine, whose research under world-renowned Bartonella expert Dr. Edward Breitschwerdt investigates how Bartonella bacteria alter gene expression in the brain's immune cells. Guest Janice Bush, DVM, PhD Candidate College of Veterinary Medicine, North Carolina State University (NCSU) Dr. Janice Bush began her career in veterinary medicine, where she observed a striking overlap between illnesses in pets and their human owners—particularly those linked to vector-borne infections like Bartonella. Now completing her PhD under Dr. Edward Breitschwerdt, she focuses on Bartonella henselae, the bacterium behind Cat Scratch Disease, and its ability to infect human microglial cells—the brain's resident immune defenders. Her presentation, “Bartonella-Infected Human Microglial Cells: Transcriptional Changes Associated with Chronic Neurologic Disorders,” revealed how this stealth pathogen triggers widespread gene dysregulation linked to Alzheimer's disease, psychiatric symptoms, and neurodegenerative processes. Key Discussion Points Dr. Bush explains how Bartonella infection reprograms human microglia, the brain's innate immune cells, leading to hundreds of genes being upregulated or suppressed—affecting energy metabolism, mitochondrial function, cell signaling, and immune communication. These cellular changes mirror those observed in chronic neurological and psychiatric disorders, providing a potential mechanistic link between infection and long-term neurodegeneration. She describes Bartonella's sophisticated immune evasion strategy, including its ability to hijack cellular machinery and increase production of interleukin-10 (IL-10)—an anti-inflammatory cytokine that suppresses immune response, allowing the bacteria to persist undetected. This mechanism may explain why patients experience cyclic flares and remissions, and why Bartonella can linger silently for years. Dr. Bush's findings suggest that even short-term infections can produce measurable transcriptional changes in brain immune cells within 48 hours. If such infections persist for months or years, they may set the stage for neurodegenerative disease, particularly when combined with other pathogens or environmental factors. “If one intracellular pathogen can cause this many changes in two days, imagine what happens over months or years. Bartonella may be the spark that primes the brain for neurodegeneration.” — Dr. Janice Bush Why It Matters Dr. Bush's research offers a groundbreaking look at how a common, underrecognized infection may drive neuroinflammation and neurodegeneration. Her work bridges veterinary medicine, infectious disease, and neurology—revealing how pathogens once dismissed as minor or self-limiting may alter the brain's immune landscape. By demonstrating that Bartonella can infect and manipulate microglial cells, she provides critical biological evidence linking vector-borne disease and cognitive decline, paving the way for future diagnostic and therapeutic innovation. About the Event This interview was recorded at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and Philadelphia College of Osteopathic Medicine (PCOM) Symposium, held October 3, 2025, at Ohio University in Dublin, Ohio. The event gathered more than 20 leading researchers exploring how microbes, the microbiome, and immune dysregulation contribute to Alzheimer's, dementia, and infection-associated chronic illness (IACI). The Tick Boot Camp Podcast, in partnership with Ali Moresco and Nikki Schultek, documented these conversations to connect the chronic Lyme, infectious disease, and Alzheimer's research communities. This episode is part of Tick Boot Camp's AlzPI collaboration series. Learn More Learn more about the Alzheimer's Pathobiome Initiative (AlzPI) Listen to Tick Boot Camp Podcast episodes, including Episode 406: Pathobiome – An Interview with Nikki Schultek and Episode 101: The Young Gun – An Interview with Alex (Ali) Moresco discussed in this interview.

Above Deck
248. Below Deck Med S10, Ep11: When You Kiss Joe Bradley, You Get an Infection.

Above Deck

Play Episode Listen Later Dec 9, 2025 38:45


Sarah and Kelli discuss Season 10 episode 11 of Below Deck Med. Topics include: the mid-season slump, Nathan missing Gael, Max and Cathy's talk, hot charter guests, America's Cup, Joe becoming lead deckhand, Kizzi rushing dinner, V not feeling well, espionage, Max letting another guest drive the tender, a listener comment and who follows who according to @bravo.lytics. In Hot Tub Convo we discuss Max and V's WWHL appearance, Fraser's health scare, Kate Chastain on Reality Hot Seat, watching BravoCon panels on Peacock and we ask for podcast app reviews! He's too beautiful to be a fighter, and a new episode of Above Deck is out now! Follow us on Instagram: @abovedeckpod   Get in touch: abovedeckpod@gmail.com  Get ya some Above Deck merch: https://shop.hurrdatmedia.com/collections/above-deck  If you're struggling and think you'd benefit from a therapy session, go to betterhelp.com/Abovedeck or choose Above Deck during signup and get 10% off your first month of therapy.  Please subscribe on Apple Podcasts, Spotify or wherever you get your podcasts, and tell a friend! Resources: instagram.com/bravo.lytics/ This is another Hurrdat Media Production. Hurrdat Media is a podcast network and digital media production company based in Omaha, NE. Find more podcasts on the Hurrdat Media Network by going to HurrdatMedia.com or the Hurrdat Media YouTube channel! Learn more about your ad choices. Visit megaphone.fm/adchoices

The School of Doza Podcast
What Really Happens When You Catch the Flu?

The School of Doza Podcast

Play Episode Listen Later Dec 8, 2025 30:07


Learn exactly how the flu makes you sick and how to interrupt each phase of infection. Discover the science-backed supplements that act as "fire extinguishers" for inflammation, why vitamin D and NAC are essential during flu season, and how to support your immune system before, during, and after viral infections to recover faster and stay healthier year-round. 5 KEY TAKEAWAYS The flu is a viral infection that never truly leaves your body – it can lay dormant and flare up during times of stress, making prevention and immune support crucial year-round, not just during illness. Vitamin D and NAC are your immune system's "fire extinguishers" – both reduce pro-inflammatory cytokines (like TNF-α and IL-6) that cause severe lung inflammation during flu infections, helping you recover faster and experience less severe symptoms. NAC does triple duty during flu season – it thins mucus for easier breathing, reduces inflammation in the lungs, and boosts glutathione production (your body's master antioxidant) to fight viral infections more effectively. Most people are deficient in the nutrients needed to fight flu – vitamin D deficiency affects most of the population, and low levels of glutathione, zinc, and selenium make you more vulnerable to severe viral infections and slower recovery. Viral infections deplete your adrenal glands – the constant stress response during and after flu infection tanks your HRV and DHEAS levels, requiring adrenal support to fully recover and prevent long-term fatigue or autoimmune-like symptoms. FEATURED PRODUCT The D - provides 5,000 IU of vitamin D3, which acts as a "fire extinguisher" for inflammatory cytokines released during viral infections, reducing lung inflammation and supporting your body's natural immune response.  Find it here: https://mswnutrition.com/products/the-d TIMESTAMPS 00:00 – START 02:45 – Why the flu is a viral infection that never leaves your body 05:30 – How respiratory viruses spread and enter your system 08:15 – NAC: The game-changer for mucus, allergies, and lung inflammation 12:40 – Why vitamin D is your immune system's most powerful tool 16:20 – The science of inflammatory cytokines and how they damage your lungs 20:10 – Vitamin D studies: 10,000 IU protocol for flu prevention 24:35 – NAC and glutathione: Your body's master antioxidants explained 28:50 – Why people with fatty liver get sicker from viral infections 32:15 – Lysine, zinc, and selenium: Additional immune support nutrients 36:40 – The IV therapy protocol for sick patients in clinical practice 40:20 – Supporting your adrenal glands after flu infection 43:15 – HRV tracking and how to measure your body's stress response 46:00 – Product recommendations: The D, NAC+, Zen, and Gut Powder RESOURCES NAC Benefits for Health – https://www.drugs.com/medical-answers/nac-benefit-health-3573010/ Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths – https://pmc.ncbi.nlm.nih.gov/articles/PMC7231123/ Vitamin D and Respiratory Health – https://pmc.ncbi.nlm.nih.gov/articles/PMC4488782/ The Antioxidant Role of Non-Vitamin, Non-Mineral Micronutrients – https://pmc.ncbi.nlm.nih.gov/articles/PMC8234027/ N-Acetylcysteine and Respiratory Diseases – https://pmc.ncbi.nlm.nih.gov/articles/PMC11278452/ The Role of Zinc in Antiviral Immunity – https://pmc.ncbi.nlm.nih.gov/articles/PMC8349606/ Selenium Supplementation and Influenza Vaccine Response – https://brieflands.com/journals/jkums/articles/69746 Selenium and Viral Infections – https://pmc.ncbi.nlm.nih.gov/articles/PMC6769590/ Immune Activation and Autonomic Nervous System in Post-Viral Fatigue – https://pmc.ncbi.nlm.nih.gov/articles/PMC10795785/ Long COVID and Heart Rate Variability Study – https://www.cidrap.umn.edu/covid-19/long-covid-changes-heart-rate-variability-study-suggests CONNECT

Biomécanique
L'Expert N°1 de l'hygiène : Ce qui affaiblit VRAIMENT votre système immunitaire

Biomécanique

Play Episode Listen Later Dec 8, 2025 79:54


-10% sur votre 1ère commande Nutripure avec le code BIOMECANIQUE : ⁠https://nutripure.fr ⁠ Christophe Mercier Thellier est microbiologiste et hygiéniste. Il est spécialisé dans l'étude des agents infectieux, la prévention des risques sanitaires et les stratégies d'hygiène publique. Son dernier livre *L'Hygiène, c'est la santé !* est disponible partout.Site officiel : ⁠https://www.hygides-sante.com/⁠Instagram : ⁠https://www.instagram.com/christophemercierthellier/⁠Livre Amazon : ⁠https://amzn.to/3KHe6GZ⁠ CHAPITRES :0:00 Introduction13:06 Infections nosocomiales et risques à l'hôpital16:41 Propagation des virus et l'importance de l'hygiène30:53 Voyage et risques microbiologiques37:23 Conseils d'hygiène en voyage40:16 Hygiène et sécurité alimentaire41:38 Collectivités à risque44:16 Besoin de réformes sanitaires46:45 Importance de l'éducation hygiénique49:39 Infection nosocomiale en hôpital52:39 Micro-organismes et immunité58:09 Hygiène personnelle et habitudes1:01:01 Nature des micro-organismes1:05:10 Pratiques de prévention1:09:17 Hygiène en milieu médical1:11:46 Problème des savons antibactériens1:13:39 Impact des conservateurs alimentaires BIOMÉCANIQUE :​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Spotify⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Apple Podcasts⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Discord⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Website⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠​⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠La Lettre Biomécanique⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠™⁠⁠ Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Healthy Matters - with Dr. David Hilden
S05_E05 - Antibiotics - When They're Strong vs. When They're Wrong

Healthy Matters - with Dr. David Hilden

Play Episode Listen Later Dec 7, 2025 28:39 Transcription Available


12/07/25The Healthy Matters PodcastS05_E05 - Antibiotics - When They're Strong vs. When They're WrongWith Special Guest: Dr. Caitlin Eccles-RadtkeAntibiotics have been around for almost a century, in that time they've been responsible for saving countless lives - in both humans and in livestock.  But these meds have gone from medical marvels to "use with caution" in recent times.  But what's driving this change?  When are antibiotics actually called for and when are they ineffective?  And what's the latest on these antibiotic resistant superbugs?Antibiotics have stirred up some big conversations recently, and on Episode 5 of our show, we'll be joined by infectious disease expert Dr. Caitlin Eccles-Radtke to explore the myths, mishaps, and mind-blowing discoveries shaping antibiotic use today.  Wanna know why your doctor side-eyes unnecessary Z-packs?  This episode breaks it all down.  Join us!Got healthcare questions or ideas for future shows?Email - healthymatters@hcmed.orgCall - 612-873-TALK (8255)Get a preview of upcoming shows on social media and find out more about our show at www.healthymatters.org.

Ranch It Up
Prevent Scours Before Calving Season & Cattle Industry News

Ranch It Up

Play Episode Listen Later Dec 7, 2025 27:00


It's The Ranch It Up Radio Show! Join Jeff Tigger Erhardt, Rebecca Wanner AKA BEC and their crew as they hear how feeding Farmatan to bred cows now can help prevent scours this upcoming calving season.  Plus news, markets, updates, bred cow prices and lots more on this all-new episode of The Ranch It Up Radio Show.  Be sure to subscribe on your favorite podcasting app or on the Ranch It Up Radio Show YouTube Channel. How To Prevent Calf Scours: Feed Farmatan   Feed Farmatan To Prevent Scours This Upcoming Calving Season Calving season is getting ready to start for many producers and for some others it is still a ways away yet.  Regardless, we need to get a jump on scours and make sure each and every calf that hits the ground has the best chance of survival.  A simple solution… FARMATAN from Imogene Ingredients.   WHAT CAUSES SCOURS IN BEEF CATTLE/CALVES Clostridia-Enterotoxemia The most common form of Clostridium in cattle is caused by Clostridia perfringens. The gram-positive bacteria are a challenge due to its ability to form spores and lay dormant for long-periods of time. The bacteria reproduce by releasing spores into its environment (soil, feed, manure). The spores can even lay dormant in the animal's intestine until opportunity presents itself. Infection takes place either through ingestion of spores or through an open wound. The most severe cases happen within the first month of a calf's life, and can result in sudden death. Clinical Signs Diarrhea - Bloody, Mucus Present, Bubbly Dehydrated Bloat Blindness Prevention/Treatment: Prevention can be difficult due to the Clostridia spores being extremely durable and present almost everywhere. Complete cleanout and disinfection between calves is helpful, but not always effective. A good vaccination program will reduce clinical disease. The best method is to develop good gut health and the immune system of the calf. Farmatan has been shown to strengthen the intestinal wall, helping to prevent infection from taking hold. Coccidiosis Cattle are host to numerous species of Coccidia, a single-celled protozoal parasite. Infection and clinical symptoms can happen any time during a calf's life, with the most severe reaction usually occurring between 3-6 weeks of age. The life-cycle of coccidia requires time to infect the intestine causing destruction of the mucosal and epithelial lining. The oocytes mature outside the host in warm, moist environments before being consumed, causing infection of a new host. Clinical Signs Diarrhea - Watery, Bloody Depression Weight Loss Prevention/Treatment: Prevention of Coccidiosis is possible by keeping young calves separate from older animals, providing clean water and feed, and dry conditions. Isolation of infected animals is key to preventing transmission. Keeping the pen dry is the most important step a farmer/rancher can take in preventing Coccidiosis. Treatment can have a good impact on reducing secondary disease, and speeding up recovery time. Farmatan has been shown to disrupt the reproductive cycle of Coccidia; and may help strengthen the intestinal wall to prevent infection, in both the cow and calf. Coronavirus Bovine Coronavirus is a ubiquitous, envelope-viral disease, causing respiratory and enteric infection. There are many serotypes for this virus, making it difficult to test for, and create a vaccine. Coronavirus can present as either diarrhea and/or respiratory illness; transmitted through nasal discharge and/or feces. Animal reservoirs continue to spread the disease, and make eradication almost impossible. Clinical disease will likely occur between days 10-14, and present for up to 4 days. Clinical Signs Diarrhea - Watery Nasal Discharge Coughing Prevention/Treatment: Prevention is difficult due to wild animals transmitting the disease. Keeping wild animals out of animal enclosures is essential. Isolation of infected animals is critical to preventing the spread of Coronavirus. Adequate colostrum intake, along with a good vaccination program will help prevent clinical disease. Learn more about the positive effects of Farmtan's active ingredient on Coronavirus HERE. Cryptosporidium Cryptosporidium Parvum is a single-celled parasite responsible for causing infection in young calves. The infection takes place within the first four weeks of a calves' life, afterwards immunity has developed within the calf. The parasite is either passed from the cow or spread through infected water sources. Clinical Signs Diarrhea - Watery, Bloody, Mucus present Colic Depression Prevention/Treatment: Good sanitary conditions, especially clean water is essential in preventing transmission of cryptosporidium. Isolation of sick calves will help reduce the effect on the overall herd. There is some good effect of calves given adequate colostrum, however this is likely helping by reducing other pathogenic loads rather than a direct effect on Cryptosporidium, itself. Farmatan fed prior to calving has been shown to disrupt the life-cycle and reduce transmission from the cow. The direct action of Farmatan on the parasite makes it an excellent choice for treating calves. Learn more about the positive effect of Farmatan's active ingredient HERE. E-Coli Escherichia Coli is a bacterial infection that affects calves within the first week of their life. The bacteria colonize in the lower intestine and produce a toxin. The toxin causes excessive secretion of fluids. The zoonotic disease has special importance in food safety and human health. Colostrum and natural immunity are often not sufficient in preventing infection in cases of high bacterial concentrations. Clinical Signs Diarrhea - Creamy, Yellow Abdominal Pains Fever Vomiting Prevention/Treatment: The best prevention methods for E. Coli include: clean water, dry bedding/environment, isolation of infected animals, and vaccination. Treatment with antibiotics and oral fluids have great benefits in reducing clinical symptoms of the disease. Farmatan has been shown to reduce bacterial load and help prevent infection. Learn more about the positive effects of Farmatan's active ingredient HERE. Rotavirus Rotavirus in calves is caused by a virus belonging to the Reoviridae family, as a non-envelope RNA virus. Rotavirus is thought to be the most common cause of neonatal diarrhea in calves. The virus tends to affect calves between the age of 1-day-old up to a month, with most cases presenting within the first week of life. Shedding and reinfection can happen in older calves and cows. Clinical symptoms are rarely present after the first month of life; older animals tend to either be carriers or asymptomatic. The majority of herds have some level present, with transmission likely happening during or shortly after birth. Clinical Signs Diarrhea - Pale Yellow, Bloody Dehydrated Dull calves Reluctant to drink Prevention/Treatment: The ideal scenario is to prevent infection through, sanitary facilities (calving barn), outdoor calf housing, and a good vaccination program. Colostrum will provide much needed antibodies, protecting the calf before their immune system is fully developed to combat the disease. Farmatan fed prior to calving can help reduce the pathogen load of the cow, reducing the likelihood of transmission. Farmatan supplemented in the milk has been shown to decrease the virus' ability to cause infection and clinical disease. The best treatment for calves already presenting clinical disease is to administer oral fluids/electrolytes to rehydrate the calf. Learn more about the positive effect of Farmatan's active ingredient HERE. Salmonella Salmonella infection of cattle is caused by a variety of species within the family. While the disease is uncommon in cattle with little effect on calf health, it has massive implications for human health and food safety. The bacteria spreads through direct contact or contaminated feed & water. This disease is highly regulated by the USDA. The most severe cases of salmonella affect calves between the ages of 7-10 days old. Clinical Signs Diarrhea - Bloody (flakes of slough tissue), Watery, Mucus present Lethargic Fever Prevention/Treatment: Prevention is always the best option: provide clean water, feed, and bedding. Isolate infected animals, ensure adequate colostrum intake, and develop a vaccination program with your veterinarian. Treatment with antibiotics and fluids (oral or intravenous) greatly increases the survival rate of calves infected with Salmonella. Farmatan has been shown to help reduce the likelihood of infection by protecting the gut, and reduce recovery time of infected animals.  LEARN MORE ABOUT IMOGENE INGREDIENTS  PRODUCTS Paul Mitchell & Paul Martin on RFD TV Rural America Live!  WATCH: https://vimeo.com/759549430/bd063fcc1f Beef Industry News Possible Slow Beef Trend in 2026 According To Rabobank Beef production by major global producers is expected to remain sluggish next year, according to analysts at the Dutch financial services cooperative Rabobank. The recent contraction in beef production is expected to affect major producers in Brazil, Canada and the United States, with New Zealand being likely to see the sharpest percentage drop in beef production, the Rabobank report predicted. Several issues are contributing to the 2025 decline and the expected drop next year, especially in light of limited cattle herds ready for slaughter in both the United States and Brazil, the report added. The long-term contraction of available cattle is being blamed for significant price hikes for retail beef in the last few years, Rabobank noted. Canada is experiencing a tighter pattern that has resulted in a decline of 41,000 metric tons of beef available for export in 2025 versus levels in 2024, according to the report. Canadian beef output in 2026 is expected to be “more limited” compared with this year for reasons also being experienced south of the Canadian border in terms of the available cattle herd. References: https://meatingplace.com/slower-beef-production-trend-to-continue-in-2026-rabobank/?utm_source=omeda&utm_medium=email&utm_cid=1103020073&utm_campaign=MTGMCD251201004&utm_date=20251201-1300 New World Screwworm Website Tracks Parasite There's a new way for producers and other stakeholders to track the fight against the New World Screwworm — a parasite that threatens live cattle herds. The USDA has launched a dedicated website with up-to-date information on the spread of the screwworm, which so far has been confined to cattle in several Mexican states near the U.S. border. The site includes resources for livestock producers, veterinarians, animal-health officials, wildlife experts, healthcare providers, pet owners, researchers, drug manufacturers, and the general public. Reports of the pest in Mexican cattle prompted the U.S. to halt cattle imports from Mexico back in May. USDA also committed $21 million to boost sterile fly production in Mexico as part of its response. The new website pulls together information from multiple federal partners, including the FDA, the Department of Energy, Homeland Security, the EPA, and the State Department.  Reference: https://www.aphis.usda.gov/livestock-poultry-disease/stop-screwworm Nightshade In Corn Residue Could Be Toxic Have you noticed any black nightshade in your corn stalks that you are grazing or plan to graze? If these fields have too much black nightshade, be careful — it might be toxic. Black nightshade is common in many corn fields in the fall, especially those that had hail damage in the summer or any situation where the corn canopy became thin or open. It usually isn't a problem, but if the density of nightshade is very high, there is the potential that it could poison livestock. Almost all livestock, including cattle, sheep, swine, horses and poultry are susceptible.   Black nightshade plants average about two feet in height and have simple alternating leaves. In the fall, berries are green and become black as the plant matures. All plant parts contain some of the toxin and the concentration increases as plants mature, except in the berries. Freezing temperatures will not reduce the toxicity. It is very difficult to determine exactly how much black nightshade is risky. Guidelines say that a cow would need to consume three to four pounds of fresh black nightshade to be at risk of being poisoned. These guidelines, though, are considered conservative since there is little data on the actual toxicity of nightshade plants. Fortunately, even though nightshade plants remain green fairly late into the fall, cattle usually don't appear to seek out nightshade plants to graze. However, green plants of nightshade might become tempting toward the end of a field's grazing period when there is less grain, husks or leaves to consume.  References: https://www.nationalbeefwire.com/nightshade-in-corn-residue-grazing-could-be-toxic Featured Experts in the Cattle Industry Paul Mitchell – Imogene Ingredients https://www.imogeneingredients.com/ Follow on Facebook: @FarmatanUSA Kirk Donsbach – Financial Analyst at StoneX https://www.stonex.com/ Follow on Facebook: @StoneXGroupInc Shaye Wanner – Host of Casual Cattle Conversation https://www.casualcattleconversations.com/ Follow on Facebook: @cattleconvos Contact Us with Questions or Concerns Have questions or feedback? Feel free to reach out via: Call/Text: 707-RANCH20 or 707-726-2420 Email: RanchItUpShow@gmail.com Follow us: Facebook/Instagram: @RanchItUpShow YouTube: Subscribe to Ranch It Up Channel: https://www.youtube.com/c/RanchItUp Catch all episodes of the Ranch It Up Podcast available on all major podcasting platforms. Discover the Heart of Rural America with Tigger & BEC Ranching, farming, and the Western lifestyle are at the heart of everything we do. Tigger & BEC bring you exclusive insights from the world of working ranches, cattle farming, and sustainable beef production. Learn more about Jeff 'Tigger' Erhardt & Rebecca Wanner (BEC) and their mission to promote the Western way of life at Tigger and BEC. https://tiggerandbec.com/ Industry References, Partners and Resources For additional information on industry trends, products, and services, check out these trusted resources: Allied Genetic Resources: https://alliedgeneticresources.com/ American Gelbvieh Association: https://gelbvieh.org/ Axiota Animal Health: https://axiota.com/multimin-campaign-landing-page/ Imogene Ingredients: https://www.imogeneingredients.com/ Jorgensen Land & Cattle: https://jorgensenfarms.com/#/?ranchchannel=view Medora Boot: https://medoraboot.com/ RFD-TV: https://www.rfdtv.com/ Rural Radio Network: https://www.ruralradio147.com/ Superior Livestock Auctions: https://superiorlivestock.com/ Transova Genetics: https://transova.com/ Westway Feed Products: https://westwayfeed.com/ Wrangler: https://www.wrangler.com/ Wulf Cattle: https://www.wulfcattle.com/

Microbe Magazine Podcast
Clinical Trials With the Potential To Change the Management of Prosthetic Joint Infections

Microbe Magazine Podcast

Play Episode Listen Later Dec 6, 2025 47:14


Prosthetic joint infections (PJI) remain among the most devastating complications in orthopedic surgery, with increasing incidence paralleling the growth in arthroplasty procedures worldwide. While treatment protocols are well-established, evidence supporting current approaches is lacking, and outcomes remain suboptimal, highlighting the need for improved therapeutic strategies. AAC recently published a minireview of randomized controlled trials and emerging evidence for the management for these difficult to treat infection. Today, we discuss with one of the authors of the manuscript and an ID doctor specialized in PJI infections the findings of such paper. Topics discussed: Challenges of treating prosthetic joint infections. Major clinical trial data supporting different approaches for treatment and prevention of PJI Guidance for the approach to these complicated infections. Guests: David Paterson MBBS, Ph.D., Professor, Saw Swee Hock School of Public Health (Joint) Yong Loo Lin School of Public Health (Joint), Director, ADVANCE-ID, National University of Singapore, Singapore.  Ana Victoria Salas-Vargas, M.D. Assistant Professor of Clinical Medicine, Houston Methodist Academic Institute and Weill Cornell Medical College.  This episode is brought to you by the Antimicrobial Agents and Chemotherapy Journal.  Visit asm.org/aac to browse issues and/or submit a manuscript. If you plan to publish in AAC, ASM Members get up to 50% off publishing fees. Visit asm.org/joinasm to sign up.

What the Health?
The GOP Still Can't Agree on a Health Plan

What the Health?

Play Episode Listen Later Dec 4, 2025 44:43


Senate Democrats were promised a vote by mid-December on extending the enhanced subsidies for the Affordable Care Act, but Republicans still can't decide whether they want to put forward their own alternative or what that might include. Meanwhile, both the Centers for Disease Control and Prevention and the Food and Drug Administration are roiled by debates over vaccines. Alice Miranda Ollstein of Politico, Joanne Kenen of the Johns Hopkins Bloomberg School of Public Health and Politico Magazine, and Paige Winfield Cunningham of The Washington Post join KFF Health News' Julie Rovner to discuss those stories and more. Also this week, Rovner interviews KFF Health News' Aneri Pattani about her project tracking the distribution of $50 billion in opioid legal-settlement payments.  Plus, for “extra credit” the panelists suggest health policy stories they read this week that they think you should read, too: Julie Rovner: The New York Times' “These Hospitals Figured Out How To Slash C-Section Rates,” by Sarah Kliff and Bianca Pallaro.  Joanne Kenen: Wired's “A Fentanyl Vaccine Is About To Get Its First Major Test,” by Emily Mullin.  Paige Winfield Cunningham: The New York Times' “A Smartphone Before Age 12 Could Carry Health Risks, Study Says,” by Catherine Pearson.  Alice Miranda Ollstein: The Independent's “Miscarriages, Infections, Neglect: The Pregnant Women Detained by ICE,” by Kelly Rissman.  

The Birth Trauma Mama Podcast
Ep. 208: Rushed to the NICU: Navigating Pneumothorax, Infection Fears, and Postpartum Chaos ft. Kelsea

The Birth Trauma Mama Podcast

Play Episode Listen Later Dec 4, 2025 29:57


In this episode of The Birth Trauma Mama Podcast, Kayleigh sits down with Kelsea, a mom of three, to share the emotional, terrifying, and deeply transformative story of her son Oliver's birth and NICU journey a birth she hoped would finally be a peaceful experience after two difficult deliveries, but instead became her most traumatic one yet.Scheduled for a repeat C-section at 37 weeks due to rising blood pressures and a history of preeclampsia, Kelsea entered the hospital with a pit in her stomach,  a feeling she now knows was intuition. The days that followed were filled with fear and uncertainty. Oliver deteriorated quickly, and for 24 hours, doctors weren't sure what was wrong. Finally, a NICU physician discovered that he had a pneumothorax, a collapsed left lung, and early signs of sepsis. He was intubated, placed on chest tubes, and put under strict no-hold restrictions leading to a heartbreaking stretch where Kelsea couldn't touch, comfort, or even pick up her newborn son.Together, Kayleigh and Kelsea talk through:

American Journal of Gastroenterology - Author Podcasts
Infections in Standard or Tapered Dose of Prednisolone for Alcohol-Associated Hepatitis: A Randomized Trial (STASH Trial)

American Journal of Gastroenterology - Author Podcasts

Play Episode Listen Later Dec 3, 2025 9:35


Looking at Lyme
78. Discussing undiagnosed tick-borne infections, grief, action, and science with Nicole Bell

Looking at Lyme

Play Episode Listen Later Dec 2, 2025 39:07


In this episode, we talk with Nicole Bell, CEO of Galaxy Diagnostics and author of the memoir What Lurks in the Woods. Nicole is an experienced executive in the medical device and diagnostics industry, and holds Master's degrees in materials science and biomedical engineering. She has exceptional experience in commercializing innovative technologies, building research and development programs, and driving products through to FDA approval.Nicole's best-selling and award-winning memoir, What Lurks in the Woods, vividly details her family's experience with undiagnosed tick-borne infection. This firsthand knowledge of the devastating impact of misdiagnosed chronic illness fuels her passion to drive a new diagnostic standard of care for the industry. After losing her husband to tick-borne illness, Nicole set out to use her engineering skills and experience to ensure that no family would have to go through something similar.ShownotesGalaxy DiagnosticsCenter for Lyme Action: State of the researchWhat Lurks in the Woods

Youth BiOY
Day 335: How to Avoid Spiritual Infections

Youth BiOY

Play Episode Listen Later Dec 1, 2025 13:40


Psalm 136:23-26, Daniel 7:1-14, 1 John 2:12-27. Yet you have the powerful spiritual ‘antiseptic' to use against these destructive forces It is vital that you learn to do so

Bible In One Year Express
Day 335: How to Avoid Spiritual Infections

Bible In One Year Express

Play Episode Listen Later Dec 1, 2025 14:08


Psalm 136:23-26, Daniel 7:1-14, 1 John 2:12-27. Yet you have the powerful spiritual ‘antiseptic' to use against these destructive forces It is vital that you learn to do so

Communicable
Communicable E41: Diagnostic stewardship

Communicable

Play Episode Listen Later Nov 30, 2025 62:07


In the last ten years, 'diagnostic stewardship' has emerged as a core principle of good clinical practice whose implementation impacts both the individual patient and public health at large. In this episode of Communicable, hosts Angela Huttner and Annie Joseph invite two experts in the field, Daniel Morgan (Maryland, USA) and Valerie Vaughn (Utah, USA), to discuss diagnostic stewardship in the context of infectious diseases, hospital medicine, and healthcare in general. Other topics covered include practical interventions for better testing practices and the role of artificial intelligence in the future of diagnostics. The episode highlights how thoughtful, intentional diagnostic practices can enhance clinician workflows and improve patient outcomes.This episode is a follow-up from Morgan's recently published commentary in CMI Communications on diagnostic testing, and the need for evaluating its clinical impact [1]. The episode was peer reviewed by Özlem Türkmen Recen of Çınarcık State Hospital, Yalova, Türkiye. ReferencesBaghdadi JD & Morgan DJ. Diagnostic tests should be assessed for clinical impact. CMI Comms 2024. DOI: 10.1016/j.cmicom.2024.105010Further readingAdvani S and Vaughn VM. Quality Improvement Interventions and Implementation Strategies for Urine Culture Stewardship in the Acute Care Setting: Advances and Challenges. Curr Infect Dis Rep 2021. DOI: 10.1007/s11908-021-00760-3 Core Elements of Hospital Antibiotic Stewardship Programs, https://www.cdc.gov/antibiotic-use/hcp/core-elements/hospital.html Core Elements of Hospital Diagnostic Excellence (DxEx), https://www.cdc.gov/patient-safety/hcp/hospital-dx-excellence/index.htmlCosgrove SE & Srinivasan A. Antibiotic Stewardship: A Decade of Progress. Infect Dis Clin North Am 2023. DOI: 10.1016/j.idc.2023.06.003 Dik JH, et al. Integrated Stewardship Model Comprising Antimicrobial, Infection Prevention, and Diagnostic Stewardship (AID Stewardship). J Clin Microbiol 2017. DOI: 10.1128/jcm.01283-17Fabre V, et al. Principles of diagnostic stewardship: A practical guide from the Society for Healthcare Epidemiology of America Diagnostic Stewardship Task Force. Infect Control Hosp Epidemiol 2023. DOI: 10.1017/ice.2023.5 Huttner A, et al. Re: ‘ESR and CRP: it's time to stop the zombie tests' by Spellberg et al. CMI 2025. DOI: 10.1016/j.cmi.2024.09.016 Morgan DJ, et al. Diagnostic Stewardship—Leveraging the Laboratory to Improve Antimicrobial Use. JAMA 2017. DOI:  10.1001/jama.2017.8531 Messacar K, et al. Implementation of rapid molecular infectious disease diagnostics: the role of diagnostic and antimicrobial stewardship. J Clin Microbiol 2017. DOI: 10.1128/jcm.02264-16Messacar K, et al. Clinical and Financial Impact of a Diagnostic Stewardship Program for Children with Suspected Central Nervous System Infection. J Pediatr. 2022. DOI: 10.1016/j.jpeds.2022.02.002  Qian ET, et al. Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial. JAMA 2023. DOI: 10.1001/jama.2023.20583 Siontis KC et al. Diagnostic tests often fail to lead to changes in patient outcomes. J Clin Epidemiol 2014. DOI: 10.1016/j.jclinepi.2013.12.008Vaughn VM, et al. Antibiotic Stewardship Strategies and Their Association With Antibiotic Overuse After Hospital Discharge. Clin Infect Dis 2022. DOI: 10.1093/cid/ciac104Vaughn VM, et al. A Statewide Quality Initiative to Reduce Unnecessary Antibiotic Treatment of Asymptomatic Bacteriuria. JAMA Intern Med 2023. DOI: 10.1001/jamainternmed.2023.2749  

Vitality Radio Podcast with Jared St. Clair
#591: Homeopathy Made Simple: A Powerful, Safe, Natural Medicine for the Whole Family with Paola Brown

Vitality Radio Podcast with Jared St. Clair

Play Episode Listen Later Nov 29, 2025 72:16


On this episode of Vitality Radio, Jared welcomes homeopathy educator and advocate Paola Brown, president of Americans for Homeopathy Choice. Together, they break down what homeopathy really is, how it works, and why it continues to help families around the world—even when the mainstream medical world insists it “shouldn't.” Paola shares her personal healing story, practical guidance for beginners, simple ways parents can confidently use homeopathy for everyday acute issues, and when to seek support from a homeopath for chronic conditions. You'll also hear why the FDA has recently threatened access to homeopathic remedies and what Paola's organization is doing in Washington, D.C. to keep these safe, affordable remedies available for everyone. Jared and Paola discuss potency selection, how to identify the right remedy, and why homeopathy often succeeds where other natural tools don't—especially for children and even animals. If you've ever been curious, skeptical, or confused about homeopathy, this conversation makes the entire system feel approachable, actionable, and empowering. And if you're already a believer, you'll walk away with even more tools, stories, and insights to support your family's wellness—naturally and safely.Products:Ollois Homeopathic RemediesAdditional Information:PaolaBrown.com/freeHomeopathyChoice.org/freeTo schedule your Homeopathy Consultation with Amanda Kotter:Email Amanda@vitalitynutrition.comCall/Text 801-388-4133Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

My Happy Thyroid
Ep. 245: Viral Triggers: When Infections Spark Hashimoto's

My Happy Thyroid

Play Episode Listen Later Nov 28, 2025 13:37


Could a past virus be the missing link behind your Hashimoto's? In this episode of Paloma's My Thyroid Health podcast, we unravel the hidden connection between viral infections and Hashimoto's thyroiditis — and what that means for your health.Join Paloma Health as we explore:How your immune system's fight against a virus can backfire, triggering an autoimmune attack on your thyroid through a phenomenon called molecular mimicry. The surprising way certain viruses—like EBV, CMV, enteroviruses, and even COVID-19—may directly infect thyroid cells, fueling chronic inflammation and autoimmune flares. Why some viral infections lie dormant only to reawaken later, reactivating your immune system and worsening thyroid autoimmunity. Real-world strategies for supporting your thyroid when viral triggers are involved: immune resilience, monitoring, and balancing inflammation. If you've ever wondered why your Hashimoto's symptoms flare, or felt like your thyroid health has chronically “off” sessions — this episode shines a light on a lesser-known piece of the puzzle. 

The Orthobullets Podcast
Podiums |Trauma | DAA THA: My Wound Care Protocol and Prevention of Infection

The Orthobullets Podcast

Play Episode Listen Later Nov 27, 2025 11:22


Welcome to Season 2 of the Orthobullets Podcast. Today's show is Podiums, where we feature expert speakers from live medical events. Today's episode will feature ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Dr. H. John Cooper is titled⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ "⁠⁠⁠DAA THA: My Wound Care Protocol and Prevention of Infection⁠⁠⁠⁠."Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Orthobullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on Social Media:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YouTube

The Conversation Weekly
The 40 scientists who decide which flu shot you'll get

The Conversation Weekly

Play Episode Listen Later Nov 27, 2025 26:05


Twice a year, 40 scientists gather together for five days to decide what strains of influenza to vaccinate against for the next flu season. It takes around six months to prepare the vaccine – which usually includes protection against three different strains of flu. Europe and the US are heading into a flu season that some are warning could be particularly severe this winter. While even as summer approaches in Australia, the country is still registering high numbers of cases after a record-breaking flu season earlier in the year. So how does the process of deciding on a flu vaccine each year actually work? And does what happens in the southern hemisphere influence the way the virus circulates in the northern hemisphere? In this episode, we speak to Ian Barr, deputy director for the WHO Collaborating Centre for Reference and Research on Influenza, based at the Peter Doherty Institute for Infection and Immunity, part of the University of Melbourne. Barr is one of those 40 scientists who attend the meetings to decide what strains to focus vaccination efforts on. This episode was produced by Mend Mariwany, Katie Flood and Gemma Ware. Mixing by Michelle Macklem and theme music by Neeta Sarl. Read the full credits for this episode and sign up here for a free daily newsletter from The Conversation.If you like the show, please consider donating to The Conversation, an independent, not-for-profit news organisation.First human bird-flu death from H5N5 – what you need to knowFlu season has arrived – and so have updated flu vaccinesFlu season has started early in the UK – here's what might be going on

CCO Infectious Disease Podcast
Optimizing Antibiotics in Acute Bacterial Skin and Skin Structure Infections for Today

CCO Infectious Disease Podcast

Play Episode Listen Later Nov 26, 2025 45:41


Listen in as experts Thomas P. Lodise, PharmD, PhD, and George Sakoulas, MD, FIDSA, explore tailored antibiotic strategies for diverse patients with acute bacterial skin and skin structure infections (ABSSSIs). Their insightful discussion focuses on antibiotic developments that followed publication of the IDSA practice guidelines in 2014 and the challenges unique to ABSSSIs, including a lack of determined bacterial etiology for many cases. PresentersThomas P. Lodise, PharmD, PhDProfessorAlbany College of Pharmacy and Health SciencesInfectious Diseases Clinical Pharmacy SpecialistStratton VA Medical CenterAlbany, New YorkGeorge Sakoulas, MD, FIDSAChief, Infectious DiseasesSharp Rees-Stealy Medical GroupAdjunct Professor of PediatricsUniversity of California San Diego School of MedicineSan Diego, CaliforniaLink to full program:https://bit.ly/4oIKwzsGet access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

The Naked Scientists Podcast
New ways to combat the Antibiotic Apocalypse

The Naked Scientists Podcast

Play Episode Listen Later Nov 25, 2025 32:49


Today, synthetic bacteriophages, a breakthrough vaccine for TB, and how unpicking the pathways used to make antibiotics are helping scientists to combat rising rates of antimicrobial resistance around the world... Like this podcast? Please help us by supporting the Naked Scientists

Rheuminations
The history of giant cell arteritis: Infections, injections and the man who couldn't wear a hat

Rheuminations

Play Episode Listen Later Nov 25, 2025 42:30


What does a goiter and syphilis have in common with the first descriptions of giant cell arteritis? Join us as we dive into the history of the most common type of vasculitis! Intro 0:13 GCA at ACR 2025 00:30 How Brown has approached framing this episode 1:01 A primer leading us to GCA 3:15 Let's get to the story 4:02 The man who couldn't wear a hat 4:57 Dr. Bayard Horton's 7:40 A tangent on cluster headaches 8:27 Let's get back to GCA 13:16 The first temporal artery biopsy 14:28 Vision loss and other puzzle pieces of GCA 16:27 What about jaw claudication? 21:15 Could GCA be transmissible? Injecting ground temporal arteries into healthy volunteers 24:13 Oxygen? Histamines? Adrenal cortical extract? Looking for GCA treatments 26:55 Steroids and GCA 28:40 A quote from the 1959 Mayo Clinic Board of Governors 32:24 Extracranial involvement in GCA 33:24 When did we recognize aorta involvement? Syphilis enters the picture 35:08 A recap of the history of GCA 41:25 Thanks for listening 42:19 We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum. References: Boes CJ, Cephalalgia. 2007;doi:10.1111/j.1468-2982.2007.01238.x Cummer CL, et al. JAMA. 1912;doi:10.1001/jama.1912.04270080101004 Horton BT, Proc Cent SOC Clin Res. 1946 Sproul EE, et al. Am J Pathol. 1937;PMID: 19970328 Disclosures: Brown reports no relevant financial disclosures.

Tick Boot Camp
Episode 545: Using the Human Eye to Detect Early Alzheimer's and Infection-Induced Brain Changes – Dr. Sean Miller (Yale)

Tick Boot Camp

Play Episode Listen Later Nov 25, 2025 11:19


Overview This special episode of the Tick Boot Camp Podcast was recorded live at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and PCOM Symposium in collaboration with Pathobiome Perspectives. Hosted by Ali Moresco in partnership with Nikki Schultek, Executive Director of AlzPI, the conversation brings the Tick Boot Camp mission of exploring infection-associated chronic illness (IACI)—including Lyme disease and other tick-borne infections—to the global Alzheimer's and neuroimmunology research community. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen partnered with Ali and Nikki to highlight leading scientists connecting infection, immune dysfunction, and cognitive decline. This episode features Dr. Sean Miller, a neuroscientist and co-investigator in the Logan Lab with a primary appointment at Yale School of Medicine, who is developing ways to non-invasively detect Alzheimer's-like pathology through the eye. Guest Sean Miller, PhD Co-Investigator, Logan Lab / Yale School of Medicine Dr. Sean Miller completed pre-doctoral work at Harvard Medical School, earned his PhD from Johns Hopkins University, and completed post-doctoral training at Stanford University. His research focuses on neurodegeneration, neuroglia, and early diagnostic strategies for Alzheimer's and related diseases. At the AlzPI & PCOM Symposium, Dr. Miller presented evidence showing that SARS-CoV-2 (COVID-19) infection can accelerate Alzheimer's-like pathology and that these changes can be detected non-invasively through retinal imaging. His findings suggest that amyloid-beta, a protein long associated with Alzheimer's disease, may also serve as part of the brain's antimicrobial defense system—trapping pathogens like a mesh or biofilm, but leading to damaging plaque buildup when overproduced. Key Discussion Points Dr. Miller describes how the COVID-19 virus can act as an infectious trigger for neuroinflammation and amyloid buildup, how the eye provides a unique window into the brain, and why early detection is essential to preventing neuron death. He shares how his lab's AI-enhanced retinal imaging research at Yale Eye Center is identifying amyloid and tau deposits in patients with long COVID-related brain fog—opening the possibility of routine eye exams doubling as early Alzheimer's screening tools. He explains potential therapeutic strategies, such as limiting amyloid production during infection flare-ups and enhancing clearance mechanisms afterward to reduce chronic plaque formation. The conversation also explores his scientific journey—from designing Alzheimer's drugs at Harvard and Johns Hopkins to realizing the need for early disease detection during his postdoc at Stanford—and how the pandemic inspired his focus on infection-induced neurodegeneration. “We believe neurons are exposed to pathogens in the central nervous system and respond by secreting amyloid-beta to trap them. Excessive plaque buildup from repeated or severe infections may be what drives long-term neurodegeneration.” — Dr. Sean Miller Why It Matters Dr. Miller's research connects infectious disease, ophthalmology, and neurology, providing a revolutionary new method to screen for early Alzheimer's-like changes non-invasively through the human eye. His work suggests that infections like COVID-19 may trigger the same protective—but damaging—immune responses implicated in chronic conditions such as Alzheimer's disease and infection-associated cognitive decline. About the Event The interview took place at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and Philadelphia College of Osteopathic Medicine (PCOM) Symposium, held on October 3, 2025, at Ohio University in Dublin, Ohio. The event brought together more than 20 global researchers exploring how microbes, the microbiome, and the immune response contribute to Alzheimer's, dementia, PANS/PANDAS, and infection-associated chronic illnesses (IACI). Tick Boot Camp partnered with Ali Moresco and Nikki Schultek to share the voices of researchers advancing the field of infection-associated chronic illness. This episode is part of a multi-part Tick Boot Camp series highlighting how pathobiome and microbiome science are transforming the understanding of Lyme disease, infection, and neurodegeneration. Learn More Learn more about the Alzheimer's Pathobiome Initiative (AlzPI) Listen to Tick Boot Camp Podcast episodes, including Episode 406: Pathobiome – An Interview with Nikki Schultek and Episode 101: The Young Gun – An Interview with Alex (Ali) Moresco discussed in this interview.

Coach Cody
Burnout, a Spine Infection, and the Wake-Up Call We Didn't See Coming

Coach Cody

Play Episode Listen Later Nov 24, 2025 48:02


The coach cody podcast is back! We get into why we had to stop everything — including a sudden spine infection (dyskitis/osteomyelitis), repeating fevers, a PICC line, and the burnout that had been brewing long before any hospital stay.This is the most honest breakdown we've ever done about stress, burnout, creator pressure, chronic pain, and what happens when your body finally hits the brakes for you.We cover: The full story behind the dyskitis/osteomyelitis diagnosisHospital chaos, fevers, and the 3am “get to the ER now” phone callWhat burnout actually looks like (and why so many people miss it)How stress and overworking can wreck your immune systemThe pressure of being a coach/creator during burnoutIdentity, productivity, and learning to rest without guilt.Dez's perspective as a partner navigating the whole nightmare.Why we're shifting the tone of the show to be more real + sustainableWhat recovery looks like from here — mentally and physically. If you've been feeling burned out, overwhelmed, exhausted, or like you're pushing through when your body is begging you to stop… this episode is for you.

Blood Cancer Talks
Episode 67. Management of CMV in Hematologic Malignancies

Blood Cancer Talks

Play Episode Listen Later Nov 23, 2025 40:01


Join hosts Eddie, Ashwin, and Raj as they welcome Dr. Michelle Yong and Dr. Gemma Reynolds, academic infectious diseases physicians from the Peter MacCallum Cancer Centre and the National Centre for Infections in Cancer, for an in-depth discussion on cytomegalovirus (CMV) management in immunocompromised hematology patients.Key Topics CoveredFundamentals of CMV ManagementDistinguishing CMV reactivation from CMV diseaseTreatment thresholds and target viral loadsProphylaxis strategies in non-allograft settingsValaciclovir dosing in general hematology populationsHigh-risk patient populationsFirst-Line TherapiesValganciclovir: advantages, disadvantages, and myelosuppressionFoscarnet: indications and monitoring strategiesTreatment-resistant CMVAllogeneic Transplant PatientsHigh-risk populations and timing of reactivationMonitoring protocols post-transplantRandomized Controlled TrialsAURORA Trial: Maribavir vs. ValganciclovirDesign: RCT comparing maribavir to valganciclovir for pre-emptive CMV therapy post-allogeneic transplant [https://pubmed.ncbi.nlm.nih.gov/38036487/]NEJM Letermovir Prophylaxis TrialDesign: Double-blind, placebo-controlled RCT of letermovir prophylaxis post-allogeneic transplant [https://pubmed.ncbi.nlm.nih.gov/29211658/]Emerging Patient PopulationsCMV in lymphoma and myeloma patients receiving CAR T-cell therapy and T-cell engaging bispecific antibodiesMonitoring and prophylaxis strategies for novel immunotherapiesImpact of CMV on post-CAR T mortality-https://pubmed.ncbi.nlm.nih.gov/40203190/

5 Things
When preventable infections turn deadly behind bars

5 Things

Play Episode Listen Later Nov 20, 2025 16:45


A USA TODAY exclusive investigation found thousands of in-custody deaths that could have been easily prevented. USA TODAY Investigative Data Reporter Austin Fast explains what the records reveal about sepsis, medical neglect and the human cost for families left behind. He shares stories from jails and prisons across the country, including people who died waiting for basic care and inmates who feared punishment for asking for help.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The Derm Vet Podcast
299. The many faces of pyoderma

The Derm Vet Podcast

Play Episode Listen Later Nov 20, 2025 14:23


Send me a question or story!For how common we see pyoderma in cats and dogs in veterinary practice, the appearance can be variable. A cutaneous bacterial infection can appear as crusting, erythema, scaling, moth-eaten alopecia, epidermal collarette, etc. Differentials can also be varied. Pyoderma can mimic dermatophytosis, demodicosis, pemphigus foliaceus, epitheliotropic lymphoma, etc. Check out this week's episode The Derm Vet podcast! Also, I highly encourage you to check out the YouTube channel to see some clinical images.00:00 – Intro01:20 – Moth-Eaten Alopecia03:18 – Diffuse Alopecia04:21 – Erythema05:27 – Scaling06:40 – Epidermal Collarettes07:57 – Crusting11:15 – Urticaria-like Lesions13:58 – Outro

GamesMyMomFound
Sonic The Hedgehog Vol 4. Infection (Comic 97) - GMMF

GamesMyMomFound

Play Episode Listen Later Nov 20, 2025 51:16


We take a look at Volume 4 of the IDW Sonic and this one starts a new saga, the metal virus saga.  I made comments about this comic being dark so far... but learning very quickly i ain't seen nothing yet.   Come hear us talk about more sonic. Starring Mike Albertin, and Phoebe Stanton.  A Gamer Looks at 40 - https://agamerlooksat40.com/ Phoebe's Twitch - https://www.twitch.tv/theletsplayprincess Phoebe's Podcast - https://nerdsabroadcast.podbean.com/ Zac's Podcast - https://linktr.ee/absolutelythebest Helena - https://linktr.ee/helhathfury Patreon - https://www.patreon.com/GamesMyMomFound Follow us on Facebook. Instagram - gamesmymomfound_ YouTube  - https://youtube.com/c/GamesMyMomFoundPodcast Discord - https://discord.gg/ Sonic The Hedgehog Vol 3. Battle for Angel Island (Comic 95) - GMMF https://gamesmymomfoundpodcast.podbean.com/e/sonic-vol-3-battle-for-angel-island-comic-95-gmmf Sonic The Hedgehog Vol 2. The Fate of Dr Eggman (Comic 90) - GMMF https://gamesmymomfoundpodcast.podbean.com/e/sonic-vol-2-the-fate-of-dr-eggman-comic-90-gmmf Sonic The Hedgehog Vol 1. Fallout (Comic 87) - GMMF https://gamesmymomfoundpodcast.podbean.com/e/sonic-the-hedgehog-vol-1-fallout-comic-87-gmmf Shadow the Hedgehog - GMMF 182 https://gamesmymomfoundpodcast.podbean.com/e/shadow-the-hedgehog-gmmf-182 Sonic Adventure 2 - GMMF 158 https://gamesmymomfoundpodcast.podbean.com/e/sonic-adventure-2-gmmf-158 Knuckles Chaotix (Game/Comic) - GMMF https://gamesmymomfoundpodcast.podbean.com/e/knuckles-chaotix-game-and-comic-gmmf Super Sonic Vs Hyper Knuckles (Comic 15) -  GMMF https://gamesmymomfoundpodcast.podbean.com/e/super-sonic-vs-hyper-knuckles-comic-gmmf Sonic & Knuckles, Sonic 3 - GMMF 18 https://gamesmymomfoundpodcast.podbean.com/e/sonic-knuckles-sonic-3-gmmf-18

Tick Boot Camp
Episode 544: How Microbes Like Lyme May Trigger Alzheimer's and Cognitive Decline – Dr. Brian Balin (PCOM)

Tick Boot Camp

Play Episode Listen Later Nov 18, 2025 15:07


Overview This special episode of the Tick Boot Camp Podcast was recorded live at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and PCOM Symposium in collaboration with Pathobiome Perspectives. Hosted by Ali Moresco in partnership with Nikki Schultek, Executive Director of AlzPI, the conversation brings the Tick Boot Camp mission of exploring infection-associated chronic illness (IACI), like Lyme disease and other tick-borne diseases, to the global Alzheimer's and neuroimmunology research community. Tick Boot Camp co-founders Matt Sabatello and Rich Johannesen partnered with Ali and Nikki to highlight scientists whose work connects tick-borne illness, microbes, and cognitive decline. This episode features Dr. Brian J. Balin, an internationally recognized neuroscientist whose research has redefined the role of infection in contributing to Alzheimer's disease. Guest Brian J. Balin, PhD Professor of Neuroscience and Neuropathology Director, Center for Chronic Disorders of Aging Philadelphia College of Osteopathic Medicine (PCOM) Dr. Balin directs the Center for Chronic Disorders of Aging and the Adolph and Rose Levis Foundation Laboratory for Alzheimer's Disease Research at PCOM. With a PhD from the University of Maryland School of Medicine and postdoctoral training at the University of Pennsylvania, he has devoted nearly three decades to understanding how chronic infection and inflammation trigger neurodegeneration. His pioneering discovery that the respiratory bacterium Chlamydia pneumoniae infects brain tissue helped establish the Pathogen Hypothesis of Alzheimer's disease. His continuing work explores how tick-borne microbes — including Borrelia burgdorferi (Lyme disease), Bartonella, and Babesia — interact with other pathogens to drive neuroinflammation and cognitive decline. Key Discussion Points How infections such as Chlamydia pneumoniae, Borrelia burgdorferi, Bartonella, and Babesia were detected in Alzheimer's brain tissue. Evidence that microbes can enter the brain via the olfactory pathway or blood-brain barrier, initiating chronic inflammation, amyloid plaque formation, and tau tangle pathology. Findings from Dr. Balin's collaboration with Galaxy Diagnostics and advocate Nicole Bell, revealing polymicrobial infection and even Babesia otocoli — a strain previously believed to infect only deer — in human brain tissue. The use of animal models and 3D human brain organoids to study infection-driven neurodegeneration. Why identifying infection as part of the exposome (environmental insults over a lifetime) is key to developing precision diagnostics and treatments. Future directions: immune-modulating drugs, antimicrobials, and emerging phage therapy. “Infection is part of the exposome — an environmental insult that shapes our health over a lifetime. Recognizing that is key to truly understanding and preventing Alzheimer's disease.” — Dr. Brian J. Balin Why It Matters Dr. Balin's research bridges the worlds of neurology and infectious disease, offering a framework that could revolutionize how Alzheimer's and other neurodegenerative conditions are diagnosed and treated. By recognizing that microbes — including those transmitted by ticks — can initiate neuroinflammation and cognitive decline, his work provides hope for millions living with infection-associated chronic illness. About the Event The interview took place at the 2nd Annual Alzheimer's Pathobiome Initiative (AlzPI) and Philadelphia College of Osteopathic Medicine (PCOM) Symposium, October 3, 2025, Ohio University in Dublin, Ohio. The Symposium brought together more than 20 experts exploring how microbes, the microbiome, and the host immune response contribute to neurological and psychiatric diseases such as Alzheimer's, dementia, and PANS/PANDAS. Tick Boot Camp partnered with Ali Moresco and Nikki Schultek to document and share the voices of scientists advancing research on infection-associated chronic illness (IACI). This episode is part of a special series showcasing how pathobiome and microbiome science is changing our understanding of chronic Lyme and neurodegenerative disease. Learn More Learn about the Alzheimer's Pathobiome Initiative (AlzPI) at AlzPI.org. For Dr. Balin's publications and ongoing research, visit the Philadelphia College of Osteopathic Medicine (PCOM) website. Learn more about the Alzheimer's Pathobiome Initiative (AlzPI) Listen to Tick Boot Camp Podcast episodes, including Episode 406: Pathobiome – An Interview with Nikki Schultek and Episode 101: The Young Gun – An Interview with Alex (Ali) Moresco discussed in this interview.

Your Case Is On Hold
Infection and Nonunion in Open Fractures

Your Case Is On Hold

Play Episode Listen Later Nov 18, 2025 34:45


In this episode, Antonia and Andrew discuss the November 19, 2025 issue of JBJS, along with an added dose of entertainment and pop culture. Listen at the gym, on your commute, or whenever your case is on hold!   Link: JBJS website: https://jbjs.org/issue.php   Sponsor: This episode is brought to you by JBJS Clinical Classroom.   Subspecialties: Infection, Orthopaedic Essentials, Trauma, Hip, Knee Chapters (00:00:03) - Your Cases On Hold(00:00:45) - JBJS 10/20/20(00:03:54) - MPO ELISA test for chronic myeloperoxidase(00:11:29) - Chemical Disinfection of Accidental Infections during Orthoped(00:19:06) - Delayed Union and Nonunion Rates and Open Fractures(00:23:45) - Legacy of Open Fracture in the US(00:29:46) - How to prevent 3A in 3A patients(00:30:39) - DARE for early hip, knee infection(00:32:29) - Synovial fluid Mirnas: potential biomarkers in hip and(00:34:09) - Journals Review: The New Issue

Breakpoints
#126 – What's the Microbiome Gut to Do with It

Breakpoints

Play Episode Listen Later Nov 14, 2025 68:15


Dr. Julie Ann Justo is joined by experts Drs. Krista Gens and Javier A. Villafuerte Gálvez as they dive deep into the gut microbiome and explore the latest therapeutic frontier for C. difficile infections.  From bacteria battles to breakthrough treatments, this one's a must-listen! You can also review the helpful infographic on our website (https://breakpoints-sidp.org/infographics/). This podcast was supported by an unrestricted grant from Nestlé Health Science. References: Helpful review from one of our guest experts: Gens KD, et al. Fecal microbiota transplantation and emerging treatments for Clostridium difficile infection. J Pharm Pract. 2013 Oct;26(5):498-505. doi: 10.1177/0897190013499527. PMID: 23966282. More modern review: Herbin SR, et al. Breaking the Cycle of Recurrent Clostridioides difficile Infections: A Narrative Review Exploring Current and Novel Therapeutic Strategies. J Pharm Pract. 2024 Dec;37(6):1361-1373. doi: 10.1177/08971900241248883. Epub 2024 May 13. PMID: 38739837. Review on designing microbiota based therapies (pre-print only): Ke S, et al. Rational Design of Live Biotherapeutic Products for the Prevention of Clostridioides difficile Infection. 2024 May 02. doi: 10.1101/2024.04.30.591969. [FDA Guidance regarding IND requirements for fecal microbiota transplant](https://www.fda.gov/regulatory-information/search-fda-guidance-documents/enforcement-policy-regarding-investigational-new-drug-requirements-use-fecal-microbiota). 2022 Nov. OpenBiome webpage with resources for hospitals: How to Start an FMT Program. 2025. Peery AF, et al. AGA Clinical Practice Guideline on Fecal Microbiota-Based Therapies for Select Gastrointestinal Diseases. Gastroenterology. 2024 Mar;166(3):409-434. doi: 10.1053/j.gastro.2024.01.008. PMID: 38395525. Johnson S, et al. Clinical Practice Guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults. Clin Infect Dis. 2021 Sep 7;73(5):755-757. doi: 10.1093/cid/ciab718. PMID: 34492699. Henry Ford's experience getting fecal microbiota products for patients: Abene S. Fecal Microbiota Capsules Improve CDI Access Through Specialty Pharmacy Integration. Contagion Live. 2025 Jul 11. An international view on CDI management: Mendo-Lopez R, et al. Best Practices in the Management of Clostridioides difficile Infection in Developing Nations. Trop Med Infect Dis. 2024 Aug 19;9(8):185. doi: 10.3390/tropicalmed9080185. PMID: 39195623. Review on investigational LBP agents: Monday L, et al. Microbiota-Based Live Biotherapeutic Products for Clostridioides Difficile Infection- The Devil is in the Details. Infect Drug Resist. 2024 Feb 15;17:623-639. doi: 10.2147/IDR.S419243. PMID: 38375101. More on quorum sensing: Falà AK, et al. Quorum sensing in human gut and food microbiomes: Significance and potential for therapeutic targeting. Front Microbiol. 2022 Nov 25;13:1002185. doi: 10.3389/fmicb.2022.1002185. PMID: 36504831. Economic impacts of CDI pts: Reilly J, et al. Economic impact of multiple recurrent Clostridioides difficile infection in a community teaching hospital. Infect Control Hosp Epidemiol. 2025 Sep 29:1-3. doi: 10.1017/ice.2025.10295. Epub ahead of print. PMID: 41020576.