Stan Crooke rose from poverty to found a company that pioneered antisense drugs. After decades of struggle and years of public doubt, the company created a treatment that has saved thousands of children from the brutal disease spinal muscular atrophy.
The biggest deal ⬩ In the black ⬩ End of an era ⬩ n of 1 ⬩ Small places ⬩ A life of control ⬩ The doctor will see you now See acast.com/privacy for privacy and opt-out information.
Award season ⬩ NURTURE, and Gabriel ⬩ Kyle Derkowski's new future ⬩ The drugs of SMA ⬩ Piece of magic ⬩ Frank's Super Bowl See acast.com/privacy for privacy and opt-out information.
Ethics lessons ⬩ Biogen re-ups ⬩ The ultimate sacrifice ⬩ FDA as partner ⬩ Emma's phase 3 ⬩ Doug Kerr's bright idea ⬩ Isis to Ionis ⬩ Spinraza approval See acast.com/privacy for privacy and opt-out information.
The Larsons ⬩ The skunkworks project ⬩ The most unmet need ⬩ Instant synergy ⬩ Another first for antisense ⬩ The clinic, again ⬩ The achievements of Kathie Bishop See acast.com/privacy for privacy and opt-out information.
Rosanne saves the company ⬩ Ibis is sold ⬩ An approval ⬩ Souring on Genzyme ⬩ The end of Genta ⬩ The discovery of the SMA gene See acast.com/privacy for privacy and opt-out information.
The genomics bubble ⬩ Affinitak fails ⬩ Lynne saves the company ⬩ Hybridon pivots ⬩ New chemistries ⬩ Regulus formed ⬩ Isis as cult See acast.com/privacy for privacy and opt-out information.
Stumbling out of the gate ⬩ Launch of Vitravene ⬩ Questions about antisense ⬩ The field thins ⬩ Clinical failure ⬩ The darkest days See acast.com/privacy for privacy and opt-out information.
Rosanne ⬩ An investor emerges ⬩ Founding Isis ⬩ The old garage ⬩ A proper space ⬩ A growing antisense scene ⬩ Starting a pipeline ⬩ Isis goes public See acast.com/privacy for privacy and opt-out information.
Quits Purdue ⬩ Pharmacy school ⬩ Off to Baylor ⬩ Harris Busch ⬩ Bristol Labs ⬩ SmithKline ⬩ The death of Nancy Crooke ⬩ The end of SmithKline See acast.com/privacy for privacy and opt-out information.
Stan Crooke is born ⬩ A tenuous existence ⬩ Life with his mother ⬩ The Tech Corner ⬩ Arsenal Tech High School ⬩ Nancy ⬩ Hoodlum ways ⬩ Off to Purdue See acast.com/privacy for privacy and opt-out information.
Trailer for upcoming 10-part series, Hope Lies in Dreams. See acast.com/privacy for privacy and opt-out information.
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