Podcasts about SMA

Muscular dystrophy (MD) is a group of genetic diseases that affect about 16 to 25 per 100,000 people in the US, with the most common childhood form being Duchenne muscular dystrophy (DMD) and the most common adult form being myotonic dystrophy. The prevalence of DMD is estimated at around 1 in 3,500 live male births. Prenatal carrier screening for this is part of the ACMG Tier 3 expanded carrier panel. This is different from spinal muscular atrophy (SMA). As we recently had a patient who was a MD carrier, with affected male children, who we cared for, we decided to do a quick review of muscular dystrophy: its prevalence, genetics, and evaluation of asymptomatic maternal carriers.1. https://www.mda.org/disease/duchenne-muscular-dystrophy/causes-inheritance2.https://www.nichd.nih.gov/health/topics/musculardys/conditioninfo/causes3. https://www.nhs.uk/conditions/muscular-dystrophy/4. ACMG: https://thednaexchange.com/2022/03/30/acmg-carrier-screening-guideline-the-hypothetical-tier-3-panel/#:~:text=The%20goal%20of%20this%20ACMG,1%20in%2040%2C000%20or%20higher.

Existing home sales came in-line with expectations and September jobs bolstered what Kevin Green calls a "goldilocks print." That, paired with a VIX crush following Nvidia's (NVDA) earnings, set the floor for a solid market bounce. However, KG argues the market "still has to prove itself," with one of the biggest tests being an attempt to recapture the SPX's 20-day SMA. He later turns to the USD and Japanese Yen trade which has boomed over the last few sessions. KG also tells investors to keep all eyes on commodities, particularly gold and silver. ======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

Matt Maley sees a "change in trend" after the SPX and NDX closed below their 50-day SMA this week for the first time since April. He believes investors are taking froth out of the markets. Matt leans cautious on Nvidia's (NVDA) earnings due to the surge in A.I. spending from hyperscalers. He likes Meta Platforms (META) as a value play after the social media giant sold off post-earnings. Alphabet (GOOGL) is another favorite of Matt's but he suggests investors wait for a pullback before adding it to positions. ======== Schwab Network ========Empowering every investor and trader, every market day.Options involve risks and are not suitable for all investors. Before trading, read the Options Disclosure Document. http://bit.ly/2v9tH6DSubscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/About Schwab Network - https://schwabnetwork.com/about

The S&P 500 (SPX) managed to hold its 200-day SMA, though Charles Schwab's Kevin Horner says the price action ahead will depend on how Nvidia (NVDA) moves after Wednesday's earnings. Turning to another Mag 7 stock in Microsoft (MSFT), he's concerned with a double top that signals an avalanche to $446 if current levels can't hold. On Best Buy (BBY), Kevin talks about the technical bounce the stock can experience with the holiday season. ======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

Kevin Green points to the SPX slip under 6,600 as notable, though it's 6,550 he's watching as the crucial level for the index. With a market that's "not selling everything," KG expects the 200-day SMA to act as strong support for stocks, though a break below can signal steeper selling. He talks about how investors deleveraging in A.I. and crypto play a critical role in price action. KG later turns to a bright spot as a "bullish cross" forms in the utilities sector. ======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

Charles Schwab's Nathan Peterson talks about how the A.I. narrative shifted strongly toward negativity as concerns of hyperscalers taking on debt added to concerns of stifled profits. After the SPX bounced off its 50-day SMA multiple times before breaking Monday into Tuesday, Nate makes the case that an A.I. "capitulation" event needs to take place for technicals to see a clean reset.======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

In this episode of Money & Meaning, host Jeff Bernier speaks with Kacie Walsh, Vice President at Dimensional Fund Advisors. They explore Dimensional's evolving toolkit of tax-focused investment solutions designed to help clients keep more of what they earn. The conversation spans mutual funds, ETFs, SMAs, exchange funds, and 351 ETFs, explaining how each tool fits into a broader tax management strategy. Kacie also outlines how Dimensional's daily, data-driven approach supports personalized portfolios and long-term efficiency for investors. Topics covered: Kacie Walsh's professional background and current role at Dimensional Fund Advisors Why Dimensional's evidence-based, data-driven approach matters in tax-focused investing Overview of tax loss harvesting and why fund and ETF lineup depth supports it Differences in tax efficiency between ETFs and mutual funds—and how Dimensional narrows the gap Update on Dimensional's ETF share class application and what it means for investors SMA (separately managed account) use cases, especially for high net worth individuals How Dimensional's SMAs differ from traditional direct indexing solutions Behavioral and operational considerations of owning hundreds of individual securities Understanding portfolio lock-up and how to plan for long-term SMA use Exchange funds as tools for diversifying out of concentrated stock positions 351 ETFs as a strategy to consolidate appreciated securities tax efficiently Overview of long/short SMAs and how they attempt to generate more tax alpha How advisors and clients can assess the trade-offs in these advanced strategies Useful Links: Jeff Bernier on LinkedIn: https://www.linkedin.com/posts/jeffberniercfp_the-money-and-meaning-show-activity-7202103509700227072-h0Qn/ TandemGrowth Financial Advisors: https://www.tandemgrowth.com/ Kacie Walsh on LinkedIn: https://www.linkedin.com/in/kacie-walsh-5787a297

In episode 154, host Kevin Schaefer talks with Coach Damon Vincent from Lafayette, Louisiana. Damon is an adaptive fitness specialist who works with clients with various rare diseases and disabilities, including SMA. He talks about his journey as a personal trainer, living with his own rare disease, and building a community with others in his field. Damon's website: https://fitnessforspecialneeds.com/ ================================ To take part in our ongoing discussions regarding SMA, please visit www.smanewstoday.com/forums

Elizabeth Lasswell is a Licensed Skincare Professional and the Founder of Vela Aesthetics & Mercantile, a Holistic Medspa in Charlotte, North Carolina.In the episode, Elizabeth and Haven discuss all things skincare, including what should be in your morning and evening skincare routines, products to use and avoid, why you should be wearing (and reapplying!) SPF every day and her favorite SPF/makeup products. The two also discuss remedies for acne concerns and they cover holistic health factors that affect skin health, including how your nutrition matters just as much as what you put on your skin when it comes to radiant skin. You'll learn so much from Elizabeth in this episode! Give it a listen and share with your friends. Let's Connect!Join the HxH Insiders on Substack!HxH CoachingSupport the show: pledge less than the cost of a cup of coffee each month! Follow Health by Haven on Instagram: @healthbyhaven HxH Recipes, Articles & More: healthbyhaven.com Connect with ElizabethFollow VELA Aesthetics & Mercantile on Instagram: @velacltThank you to our sponsor, Avodah Massage Therapy! Support the show

Chris and Rosie are feeling very delicate, but they soldier on and bring you a hungover edition of SMA! There are itchy palms, a post curry update and some heating beef. The pair discuss the future of Robots, Aesop's Fables and an AI theory.  There are some filthy QTFP's that involve a Sausage Dog, a hairdryer and some old school developed photos! If you have a story for Chris and Rosie email the podcast: Shaggedmarriedannoyed@gmail.com Learn more about your ad choices. Visit podcastchoices.com/adchoices

Rachel Dashiell with Charles Schwab says the SPX holding its 50-day SMA offers a bullish signal for investors. She offers her technical analysis through the 6-month chart. On her stock picks, Rachel shows how "no trend can run forever" through Oklo Inc.'s (OKLO) explosive price action and how Expedia (EXPE) exhibited bullish traction before its recent rally.======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

3éme épisode / 5, de la série sur l'amyotrophie spinale infantile.  Episode 3 : Maladie rare – DEPISMA : Bilan de l'étude pilote du dépistage néonatal de l'Amyotrophie Spinale infantile. Invité : Pr Vincent Laugel, neuropédiatre, chef du pôle de pédiatrie des Hôpitaux Universitaires de Strasbourg, coordinateur du projet DEPISMA, et responsable du site enfant du centre de référence des maladies neuromusculaires Nord-Est Île-de-France de la filière Filnemus.  https://www.chru-strasbourg.fr/maladie/maladies-neuromusculaires/  https://www.filnemus.fr/   1️⃣   Pourquoi proposer un dépistage néonatal de l'amyotrophie spinale ? [0'33 – 1'48]  ✔️ L'amyotrophie spinale était auparavant une maladie grave et souvent mortelle avant 2 ans ✔️ Les traitements récents stoppent la progression mais doivent être commencés très tôt ✔️ Le dépistage néonatal est nécessaire pour identifier les patients avant l'apparition des symptômes. Pour plus d'informations, retrouvez notre page article : https://rarealecoute.com/lamyotrophie-spinale-infantile/ 2️⃣   Qu'est-ce que le programme DEPISMA aux auditeurs ? [1'49 – 3'38]  ✔️ Le programme DEPISMA vise à démontrer la faisabilité et l'acceptabilité d'un dépistage néonatal génétique de l'amyotrophie spinale. ✔️ Première application en France d'un dépistage néonatal basé sur l'analyse génétique. ✔️ Déploiement sur deux régions pilotes (Grand Est et Nouvelle-Aquitaine) pour tous les nouveau-nés, utilisant une goutte de sang prélevée au talon déjà utilisée pour d'autres dépistages. 3️⃣   Quels ont été les principaux défis pour sa mise en place ? [3'39-5'58]  ✔️ Déploiement technique des laboratoires et installation des équipements de dépistage génétique. ✔️ Formation et mobilisation des 81 maternités pour prélèvement et consentement parental. ✔️ Organisation d'une prise en charge rapide des nouveau-nés dépistés positifs, impliquant de nombreux professionnels. 4️⃣   Comment les jeunes parents concernés par cette maladie rare ont-ils accueilli le programme ? [5'59 -7'16]  ✔️98 % d'acceptation des familles, malgré la procédure réglementaire de consentement. 5️⃣   Quels résultats ont été obtenus grâce au projet DEPISMA ? [7'17 – 8'37]  ✔️ Sur 2,5 ans, environ 200 000 nouveau-nés dépistés, avec 20 enfants atteints identifiés. ✔️ Plus de 94 % des naissances dépistées, avec 98 % d'acceptation parentale. ✔️ DEPISMA a permis de convaincre les autorités et de lancer un dépistage national. 6️⃣   Comment le dépistage de l'amyotrophie spinale est-il actuellement mis en œuvre en France ? [8'38 – 9'31]  ✔️ Avis favorable de la HAS en juillet 2024, validant la faisabilité et l'acceptabilité du dépistage. ✔️ Mise en œuvre concrète depuis le 1er septembre 2025 dans toutes les maternités et hôpitaux de France. 7️⃣ Quelles perspectives pour l'avenir du dépistage de l'amyotrophie spinale ? [9'32 – 11'47]  ✔️ Le dépistage dès la naissance transformera la prise en charge de l'amyotrophie spinale en permettant un traitement précoce pour tous les enfants concernés. ✔️ Objectif : prévenir l'apparition de symptômes, améliorer le pronostic et adapter les traitements à chaque nouveau-né.   L'équipe : Virginie Druenne – Ambassadrice RARE à l'écoute Cyril Cassard – Journaliste/Animation Hervé Guillot - Production Crédits : Sonacom __________________________________ RARE à l'écoute est le 1er média d'influence entièrement dédié aux maladies rares : Un podcast pour faire entendre les voix de celles et ceux qui vivent, soignent et accompagnent ces maladies souvent invisibles. Les Revues Horizon pour mettre en lumière les meilleures initiatives des centres experts, pour inspirer et connecter les professionnels de santé. Des Lives engagés, pensés pour les patients, leurs proches et les associations. Un média indépendant, engagé et utile, au service d'un meilleur parcours de soin pour les patients atteints de maladies rares. Toutes nos ressources utiles sont accessibles gratuitement sur : www.rarealecoute.com

Using the tools I have, I can find stocks to add to a watch list, back test a strategy for that stock, get alerted to when to enter and exit executing trades and finding stocks to invest in. Here are the links to all the sales: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TRENDSPIDER - BLACK FRIDAY SALE - UP TO 70% OFF - up to 52 training sessions INCLUDED ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

In this KE Report Daily Editorial, we're joined by TG Watkins, Director of Stocks at Simpler Trading and Editor of the Profit Pilot, to break down the broad market rebound following the U.S. government shutdown and where traders should look for confirmation of lasting strength. Key Discussion Highlights: Liquidity Rebound: Government reopening releases cash back into markets, fueling “risk-on” buying. Technical Confirmation Needed: TG expects retests of key supports before declaring a true reversal. Chart Setup Tips: Watch the 8 EMA, 21 EMA, and hourly 50 SMA for uptrend confirmation. Metals Cooling Off: Gold, silver, and miners may need time to consolidate after sharp rallies. Crypto Strength: Ethereum, Bitcoin, Solana, and BMNR showing early institutional accumulation. Stocks in Focus: TG highlights A FRM, SKLT, GRAB, Tesla, and Robinhood as setups with potential. Click here to visit TG's site - Profit Pilot - https://www.profit-pilot.com/ -------------- For more market commentary & interview summaries, subscribe to our Substacks: The KE Report: https://kereport.substack.com/ Shad's resource market commentary: https://excelsiorprosperity.substack.com/   Investment disclaimer: This content is for informational and educational purposes only and does not constitute investment advice, an offer, or a solicitation to buy or sell any security. Investing in equities and commodities involves risk, including the possible loss of principal. Do your own research and consult a licensed financial advisor before making any investment decisions. Guests and hosts may own shares in companies mentioned.

Dans son livre L'Algérie, ma mère et moi, Smaïn Laacher nous livre une histoire personnelle, celle de la relation avec sa mère. Il en fait aussi un objet d'études pour brosser le portrait d'une génération d'immigrés algériens. Dans ce livre intime qui prend des allures d'enquête sociologique, l'auteur explore la distance qui s'est créée entre sa mère, arrivée d'Algérie au début des années 1950, mais qui n'a jamais vraiment quitté ce pays et ses traditions, et lui, élevé en France. Smaïn Laacher était l'invité de Nathalie Amar. L'Algérie, ma mère et moi est disponible aux éditions Grasset.   ► Chronique Les pionnières de la culture Marjorie Bertin s'intéresse à la poétesse et documentariste iranienne Forough Farrokhzad.   ► Reportage Amira Souilem est allé à Ramallah en Cisjordanie occupée visiter une galerie de la ville qui consacre une exposition à un artiste gazaoui.   ► Playlist du jour - Rachid Taha  - Écoute-moi Camarade - Samira Brahmia - Dzeoudji ou Quilini - Zeyne - Hilwa.

Dans son livre L'Algérie, ma mère et moi, Smaïn Laacher nous livre une histoire personnelle, celle de la relation avec sa mère. Il en fait aussi un objet d'études pour brosser le portrait d'une génération d'immigrés algériens. Dans ce livre intime qui prend des allures d'enquête sociologique, l'auteur explore la distance qui s'est créée entre sa mère, arrivée d'Algérie au début des années 1950, mais qui n'a jamais vraiment quitté ce pays et ses traditions, et lui, élevé en France. Smaïn Laacher était l'invité de Nathalie Amar. L'Algérie, ma mère et moi est disponible aux éditions Grasset.   ► Chronique Les pionnières de la culture Marjorie Bertin s'intéresse à la poétesse et documentariste iranienne Forough Farrokhzad.   ► Reportage Amira Souilem est allé à Ramallah en Cisjordanie occupée visiter une galerie de la ville qui consacre une exposition à un artiste gazaoui.   ► Playlist du jour - Rachid Taha  - Écoute-moi Camarade - Samira Brahmia - Dzeoudji ou Quilini - Zeyne - Hilwa.

SMA Kolese Gonzaga kembali menggelar Gonzaga Festival (GonzFest) 2025, ajang tahunan yang menjadi wadah ekspresi, sportivitas, dan pengembangan bakat generasi muda. Tahun ini, GonzFest mengusung tema “Bangkitkan Cita, Kobarkan Karsa” dengan konsep besar “Retro Futurism”, yang mengajak siswa untuk berefleksi pada masa lalu dan berinovasi demi masa depan.Kepala Sekolah SMA Kolese Gonzaga, Pater Eduard Calistus Ratu Dopo, menjelaskan bahwa tema tersebut dipilih agar generasi muda, khususnya Gen Z, dapat memahami nilai dari perjalanan waktu dan menjadikannya sumber inspirasi.Tidak hanya siswa dan guru yang antusias, para orang tua murid juga menunjukkan kebanggaan mereka terhadap penyelenggaraan Gonzaga Festival 2025. Salah satunya datang dari Ernest Prakasa, aktor dan sutradara ternama yang kini menjadi orang tua siswa kelas 10 di SMA Kolese Gonzaga.Dalam sambutannya, Ernest mengaku senang bisa menjadi bagian dari komunitas sekolah yang memiliki karakter kuat dan nilai-nilai yang konsisten.“Jadi saya mewakili orang tua murid, anak saya baru kelas 10 atau kelas 1 SMA. Dan mungkin buat saya, saya bangga dan saya senang banget bisa terlibat di sekolah ini, karena buat saya sekolah ini memang agak lain ya, bukan jualan ya, tapi memang bener,” ujar Ernest, Sabtu (08/11) siang. Rir#BeritaElshinta

Markets continued downside pressure at the end the trading week. Kevin Green points to a compression in consumer sentiment not helping the picture amid a blackout of economic data. He turns to the impacts on the commodity space, from silver and gold, to natural gas. As the VIX passes 20 once again, Kevin notes the SPX tapping its 50-day SMA as a metric investors need to watch into Friday's close.======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

Is this the start of a bear market? The signs were absolutely there. What happens if $NVDA can't sell in China? What's wrong with $PSIX? What's a good risk/reward stock? It's all in this episode - a solid fundamental and technical breakdown of stocks and the overall market. Here are the links to all the sales: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TRENDSPIDER - BLACK FRIDAY SALE - UP TO 70% OFF - up to 52 training sessions INCLUDED ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

Dans ce deuxième épisode de la saison SMA, le Pr Isabelle Desguerre, cheffe du service de neurologie pédiatrique de l'Hôpital Necker-Enfants Malades à Paris, et responsable du centre de référence des maladies neuromusculaires pédiatriques de l'hôpital Necker, affilié à la filière Filnemus, explique comment la prise en charge précoce et pluridisciplinaire peut changer la vie des enfants atteints d'amyotrophie spinale infantile. Grâce au programme national de dépistage néonatal, chaque nouveau-né peut être dépisté dès la naissance. Les équipes spécialisées peuvent ainsi agir immédiatement et coordonner un suivi médical et fonctionnel sur mesure. Neuropédiatres, kinésithérapeutes, orthopédistes et centres de référence travaillent ensemble pour préserver la motricité, la respiration et la qualité de vie de chaque enfant.   Invitée : Pr Isabelle Desguerre, neuropédiatre, cheffe du service de neurologie pédiatrique de l'hôpital Necker-Enfants malades à Paris, et responsable du centre de référence des maladies neuromusculaires pédiatriques de Necker, affilié à la filière Filnemus. https://www.aphp.fr/necker-enfants-malades/service-de-neurologie-pediatrique  https://maladiesrares-necker.aphp.fr/maladies-neuromusculaires/  https://www.filnemus.fr/  L'équipe : Virginie Druenne - Programmation Cyril Cassard - Animation Hervé Guillot - Production Crédits : Sonacom __________________________________________________ RARE à l'écoute est le 1er média d'influence entièrement dédié aux maladies rares : - Un podcast pour faire entendre les voix de celles et ceux qui vivent, soignent et accompagnent ces maladies souvent invisibles. - Les Revues Horizon pour mettre en lumière les meilleures initiatives des centres experts, pour inspirer et connecter les professionnels de santé. - Des Lives engagés, pensés pour les patients, leurs proches et les associations. Un média indépendant, engagé et utile, au service d'un meilleur parcours de soin pour les patients atteints de maladies rares. Toutes nos ressources utiles sont accessibles gratuitement sur : www.rarealecoute.com

Stocks faced pressure Tuesday morning in an apparent tech-led sell-off. Kevin Green isn't raising the alarm, noting many tech names ran significantly higher and attributes the selling to profit-taking. He points to the SPX futures holding its 20-day SMA and expanding market breadth as other signals of strength. On the earnings front, Kevin explains why Palantir (PLTR) has sold off following stellar earnings. He later talks about Pfizer's (PFE) solid report and attempts to break out into new industries.======== Schwab Network ========Empowering every investor and trader, every market day.Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – / schwabnetwork Follow us on Facebook – / schwabnetwork Follow us on LinkedIn - / schwab-network About Schwab Network - https://schwabnetwork.com/about

Vispero has officially extended the upgrade deadline for JAWS, ZoomText, and Fusion licences, giving users extra time to transition without losing access. In this episode, Steven Scott and Shaun Preece sit down with Matthew Horspool to clear up the confusion around JAWS pricing, SMAs, and subscriptions, and what home and professional users need to know.If you've been puzzled by the recent Vispero licensing changes, this episode breaks it all down. Steven and Shaun revisit the ongoing debate about perpetual licences vs. subscriptions, why some users face high upgrade costs, and how the new deadlines impact both home and professional licences for JAWS, ZoomText, and Fusion. Matthew Horspool, assistive tech expert and certified JAWS trainer, provides detailed insight on: How perpetual licences still work in 2025 Why updating your SMA can be more cost-effective than waiting The difference between home annual licences and traditional home licences What new users and those losing sight today need to consider How access to work, DSA, and funding affect your options The hosts also discuss NVDA as a free alternative, frustrations with confusing pricing, and how clearer communication could help home users stay engaged with JAWS.Relevant LinksVispero: https://www.freedomscientific.comSight and Sound Technology: https://www.sightandsound.co.ukDouble Tap Feedback: feedback@doubletaponair.com Find Double Tap online: YouTube, Double Tap Website---Follow on:YouTube: https://www.doubletaponair.com/youtubeX (formerly Twitter): https://www.doubletaponair.com/xInstagram: https://www.doubletaponair.com/instagramTikTok: https://www.doubletaponair.com/tiktokThreads: https://www.doubletaponair.com/threadsFacebook: https://www.doubletaponair.com/facebookLinkedIn: https://www.doubletaponair.com/linkedin Subscribe to the Podcast:Apple: https://www.doubletaponair.com/appleSpotify: https://www.doubletaponair.com/spotifyRSS: https://www.doubletaponair.com/podcastiHeadRadio: https://www.doubletaponair.com/iheart About Double TapHosted by the insightful duo, Steven Scott and Shaun Preece, Double Tap is a treasure trove of information for anyone who's blind or partially sighted and has a passion for tech. Steven and Shaun not only demystify tech, but they also regularly feature interviews and welcome guests from the community, fostering an interactive and engaging environment. Tune in every day of the week, and you'll discover how technology can seamlessly integrate into your life, enhancing daily tasks and experiences, even if your sight is limited. "Double Tap" is a registered trademark of Double Tap Productions Inc. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Dans ce premier épisode de la saison consacrée à l'amyotrophie spinale infantile (SMA), le Dr Claude Cances, neuropédiatre au CHU de Toulouse et coordonnateur pédiatrique du Centre de référence des maladies neuromusculaires Atlantique-Occitanie, affilié à la filière Filnemus, nous aide à comprendre les fondements de la maladie et les signes cliniques précoces à ne pas manquer. Depuis septembre 2025, la SMA fait partie du programme national de dépistage néonatal. Chaque nouveau-né peut donc bénéficier d'un diagnostic dès la naissance, avant même l'apparition des premiers symptômes ; un tournant majeur pour la prise en charge. Un épisode essentiel pour mieux connaître la maladie, identifier les symptômes évocateurs (hypotonie, aréflexie, éveil préservé) et comprendre pourquoi chaque jour compte dans la mise en place du traitement.

Charles Schwab's Kevin Horner takes a closer look into the SPX tapping record highs, urging investors to "moderate" the trend higher after the index bounced off the 50-day SMA. As for stocks Kevin's watching, he points out Broadcom (AVGO) testing another breakout and PepsiCo's (PEP) potential to reach key resistance after recent trading activity fizzled.======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

We're on-site at the Abilities Expo in Schaumburg meeting Samantha, a freshly graduated 18-year-old heading to UIC who speaks with clarity about independence, dignity, and the everyday design of an accessible life. This isn't inspiration theater. It's practical courage: how to choose a major, compare campuses, and advocate for accommodations while keeping joy and curiosity in the driver's seat.Samantha walks us through life with a rare distal SMA, explaining her mobility in simple, honest terms and the mindset shifts that help her move from can't to how. She opens up about navigating high school among mostly able-bodied peers, finding friends who lead with respect, and attending MDA camp where perspective deepened into gratitude. We talk candidly about ramps and elevators, yes, but also about the less visible layers of access: seating layouts, syllabus flexibility, communication with professors, and the social cues that make classrooms feel human. Her plan to start at UIC and possibly transfer to UIUC illuminates the real calculus many students with disabilities face—community versus proximity, services versus cost, growth versus comfort.Family runs through this conversation like steel cable. A sister who turns visibility into pride, a mom who scouts tools and options, and a veteran dad whose philosophy is simple and strong: you can do hard things, differently.Samantha's message is one to carry: you're not alone, it might be harder, and you are more than what meets the eye.Press play for a grounded, hopeful take on college accessibility, disability advocacy, and resilience you can use. If this resonated, follow the show, leave a review, and share it with someone who needs proof that independence has many paths—and all of them start with your voice.

We discuss the transformative developments in the fixed income market with Blake Lynch from IMTC. Advancements in cloud computing and automation are streamlining the traditionally manual processes associated with fixed income investments, allowing for customized portfolios at scale. This has made SMA wrappers (Separately Managed Accounts) a lot more accessible, enabling greater transparency, direct ownership, and potential tax efficiency for the bond portfolios of an increasingly large number of investors.An “Aha moment” for George Aliferis (host):I've been involved in ETFs since the launch of Deutsche Bank's X-Trackers in 2007, and I've always believed they were an ideal wrapper for equity markets. Today they dominate. While the earlier ETFs were equity, there have been considerable developments in fixed income ETFs as well (now totalling $2 trillion in assets), but it's not straightforward. Indexing fixed income is problematic. And there's the fact that you can own a fund of AAA bonds, but still lose your capital due to the mark-to-market. This conversation has made me realize the adequacy of the SMA wrapper for bonds and its huge potential.About Blake Lynch, CETF®:Head Of Sales at IMTCMy mission is to address the industry's failure to innovate and enhance technology in the fixed income space, which has resulted in fixed income professionals being neglected and subjected to inadequate and inefficient tools. I am passionate about simplifying and optimizing bond portfolio management with innovative and user-friendly software that enables meaningful automation and optimization, or as we like to call it, decision support. This allows fixed income professionals to focus on key business activities and client goals, rather than wasting time on manual and error-prone tasks. I have a proven track record of expanding the market share and reach of IMTC's SaaS technology, leveraging my skills in new business development, sales enablement, strategic beta, and over 10 years of experience in the financial services space.Connect with Blake Lynch, CETF®:* LinkedIn: https://www.linkedin.com/in/blakejlynch/* Website: https://imtc.com/About the Show:Investology is a podcast hosted by George Aliferis, CAIA, dedicated to rethinking investment management and uncovering new ways to deliver better outcomes for investors.Listen on every podcast platform, or on YouTube.Resources Mentioned:Episode with Russell Feldman (CEO of IMTC)Episode with MJ Lytle (then-CEO of Tabula)Timestamps & Topics:00:00 Introducing a pivotal moment in fixed income02:27 Understanding Separately Managed Accounts (SMAs)04:48 The technological revolution in bond portfolio management07:56 Benefits of SMAs10:07 How IMTC works28:33 The outlook for fixed income technologyMy Investing & Investment Management channels* Investorama - Separating Investment Facts from Financial Fiction (YouTube)* Investology - Re-Think Investment Management (YouTube)* Investology in Audio versionFor B2B Brands, Marketers & PodcastersOrama (my business): helps brands grow with podcasts & videos - DM if you need help with a brand podcast or videosNewsletter about B2B marketing and podcasting: on Substack This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit investorama.substack.com

It's officially fall, and that means we're deep into the MLB playoffs, and the NHL, NFL and NBA seasons are in full swing. With it being such an exciting time for professional sports, we thought it'd be an opportune moment to revisit an episode we recorded in April, where Doug Perlman, CEO of Sports Media Advisors, demystifies the complex process of negotiating league media rights. We hope you enjoy this fascinating look into the evolution of sports media licensing in a post-cable world.  Summary: Major sporting events used to be clustered among a handful of TV channels. Now following your favourite team might require subscriptions to a whole litany of cable and streaming services. Which is to say nothing of all the licensed content you'll find spread out across social media platforms. In such a complex media ecosystem, how do organizations even begin to think about licensing their media assets? And how do they calculate their worth?Doug Perlman is the founder and CEO of Sports Media Advisors. SMA advises sports properties on their media strategies and rights negotiations. Doug has negotiated tens of billions of dollars in rights fees for some of the largest sports properties in the world, including the NFL, NASCAR, US Soccer, and the Ryder Cup, among others. Doug joins us today to discuss recent trends like the rise of streaming, the popularization of sports betting, and the emergence of AI, and all the unique challenges and opportunities they present for different leagues and organizations.Highlights:Doug's early career (3:00)Working for the NHL (4:40)Founding SMA (7:53)SMA's services (9:31)Negotiating rights deals (13:55)Cord-cutting (17:16)Impact of sports betting (18:35)Women's sports (19:37)AI in sports (20:58)Advice for young people trying to work in sports (26:12)Links:Doug Perlman LinkedInSMA LinkedInSMA WebsiteICR LinkedInICR TwitterICR WebsiteFeedback:If you have questions about the show, or have a topic in mind you'd like discussed in future episodes, email our producer, joe@lowerstreet.co.

Kevin Green offers his technical analysis on some of the biggest macro movers happening in the market. He speaks on the surge in mortgage refinancing and the mixed picture it offers for the overall housing market. He explains the "technical bounce" happening in crude oil as India seeks to pull back on some of its Russian oil purchases. Kevin later highlights the potential rebound in gold and silver after their significant sell-offs and the key role the 20-day SMA plays.======== Schwab Network ========Empowering every investor and trader, every market day.Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – / schwabnetwork Follow us on Facebook – / schwabnetwork Follow us on LinkedIn - / schwab-network About Schwab Network - https://schwabnetwork.com/about

Are you looking to save time, make money, and start winning with less risk? Then head to https://www.ovtlyr.com.The market just flashed a massive buy signal on Apple and the QQQ, and this episode breaks down exactly how that changes everything. Apple's surge just pushed the Dow up more than 500 points, igniting momentum across tech stocks — and yes, a brand-new Plan ETF trade is going live right here. Watch as we analyze the setup, execute the move, and explain how traders using OVTLYR systems are positioning for the next big breakout.This is where rules meet reality. You'll see the full Plan ETF checklist in action, including how to evaluate trend strength using the 10 EMA, 20 EMA, and 50 SMA, confirm setups with the Fear & Greed Heatmap, and identify when it's time to shift between Plan A, Plan M, Plan ETF, or Sit-in-Cash-and-Don't-F-Up. The focus? Reducing risk, increasing precision, and trading only when the data confirms it's time to strike.Key insights in this episode:✅ Apple's new buy signal and what it means for tech momentum✅ How to spot when QQQ triggers a confirmed uptrend✅ The secret to using EMA structure for clean entries and exits✅ Why market breadth and heatmap signals matter more than opinions✅ How Plan ETF gives traders a low-risk way to stay in the game✅ When to move from cash to action — and why discipline beats prediction✅ Real-time examples with Apple, Tesla, Netflix, Intel, and Amazon✅ Why “follow your plan” is the single most profitable trading ruleYou'll also see how trading psychology plays into every setup. The discussion gets real about expectations — why traders fail when they predict instead of react — and how billion-dollar fund managers like Larry Hite use data-driven signals to stay emotion-free. Expect deep dives into how risk management, position sizing, and exit signals create the foundation for consistent gains over time.As the live trade unfolds, the episode walks through using OVTLYR's Value Zone indicator to confirm price positioning within 2 ATR of the 20 EMA, checking for order blocks, and ensuring that every condition matches the playbook before entry. When those signals align, it's not just an opportunity — it's an obligation to act.Later, we break down earnings setups in Tesla, Intel, Netflix, and Amazon, explaining why these stocks often move violently around reports and how professional traders avoid gambling on news. Instead, they wait for confirmation and let the market show its hand.This episode is a masterclass in systematic trading, showing how to build conviction from structure instead of emotion. Whether you trade full-time or part-time, this walkthrough will sharpen how you identify buy signals, manage exits, and grow your account with confidence.If you want to save time, make money, and start winning with less risk, this is the one to watch. Learn how modern traders are using OVTLYR to stay ahead of every move the market makes.Gain instant access to the AI-powered tools and behavioral insights top traders use to spot big moves before the crowd. Start trading smarter today

Épisode 1380 : En 2025, le Social Media Advertising (SMA) entre dans une nouvelle ère dominée par l'automatisation et l'intelligence artificielle.Après des années de geekerie et d'optimisation continue des modes de ciblage, place à l'IA et au ciblage broad. Pour faire simple, ce n'est plus le ciblage qui compte mais le contenu des ads. On décrypte ensemble ce nouveau paradigme.—Ciblage broad : la logique algorithmiqueEn quelques mois, le ciblage broad (ou large) s'est imposé comme la norme sur Meta Ads et plus globalement les plateformes sociales. L'idée est de laisser l'algorithme explorer librement les audiences. En gros je ne lui dis rien et il va automatiquement trouver quelle est l'audience la plus adaptée et réceptive à votre publicité.Concrètement comme ça marche ? L'algorithme choisit lui-même les personnes à qui montrer tes publicités, sans que tu définisses précisément leurs centres d'intérêt, leur âge, ou d'autres critères très spécifiques.Attention, il ne “devine” pas : il s'appuie sur une énorme quantité de données comportementales et contextuelles.—En broad, le ciblage prend en compte le comportement des utilisateursCe que les gens font sur la plateforme : clics, likes, commentaires, partages, visionnages de vidéos, réactions à d'autres pubs.Ce qu'ils font hors de la plateforme, si le Pixel Meta ou l'API Conversions est installé sur ton site (par exemple, ajouter un produit au panier, visiter une page, acheter un article).Leurs habitudes d'achat en ligne, si elles sont traçables (ex. : utilisateurs qui achètent souvent sur Instagram).—En broad, le machine learning permet de développer la taille des audiences cibles Meta analyse les résultats de tes publicités en temps réel.Dès qu'il voit que certains types de personnes répondent mieux à ton annonce (par exemple, elles achètent ou cliquent plus souvent), il va automatiquement montrer la pub à d'autres profils similaires.Création ciblée : bienvenu dans l'ère du ciblage créatifFace à la disparition du micro-ciblage manuel, la création devient le nouveau levier de segmentation. Dans le passé, tu devais définir à qui tu voulais parler (âge, sexe, intérêts, etc.), puis créer une publicité adaptée à cette audience. Aujourd'hui, avec les progrès de l'algorithme de Meta, la logique s'est inversée :Ce n'est plus l'audience qui détermine la publicité, mais la publicité qui détermine l'audience.—Les nouvelles règles du SMA en 2025Automatisation totale du ciblage : l'IA construit les audiences (Advantage+ audiences, Lookalikes dynamiques).Création comme facteur de ciblage : les visuels, formats et messages remplacent les filtres d'audience.Scaling intelligent : le ciblage large + IA assure les meilleures performances dès que les données sont suffisantes.En synthèse, le SMA 2025 repose sur un nouveau couple gagnant : broad targeting piloté par l'IA et création ciblée pensée pour orienter l'algorithme. Les campagnes les plus efficaces ne découlent plus d'un paramétrage précis, mais d'une collaboration intelligente entre créativité humaine et machine.. . . Le Super Daily est le podcast quotidien sur les réseaux sociaux. Il est fabriqué avec une pluie d'amour par les équipes de Supernatifs. Nous sommes une agence social media basée à Lyon : https://supernatifs.com. Ensemble, nous aidons les entreprises à créer des relations durables et rentables avec leurs audiences. Ensemble, nous inventons, produisons et diffusons des contenus qui engagent vos collaborateurs, vos prospects et vos consommateurs. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

In this heartfelt episode of It Happened To Me, hosts Cathy Gildenhorn and Beth Glassman sit down with Nikki McIntosh, a rare disease advocate, writer, and mother whose life changed when her son Miles was diagnosed with Spinal Muscular Atrophy (SMA). Nikki McIntosh is the founder of Rare Mamas®, a resource, and community dedicated to supporting and empowering mothers of children with rare diseases. She is the author of Rare Mamas: Empowering Strategies for Navigating Your Child's Rare Disease and host of the Rare Mamas Rising podcast. Her mission stems from the profound need she felt after her son was diagnosed with a rare disease, fueling her with a passion and purpose to offer a lifeline of hope and connection to other rare moms. Nikki is a sought-after speaker and a trusted voice in the rare disease space. From national conferences and patient advocacy group gatherings to biotech industry meetings and media interviews, Nikki passionately advocates for the rare disease community. She lives in Southern California with her husband, Tony, and their sons, Mason and Miles. In 2013, at just eighteen months old, Nikki's youngest son, Miles, was diagnosed with spinal muscular atrophy (SMA)—a rare, degenerative neuromuscular disease. Told there was no treatment, no cure, and that regression was inevitable, Nikki refused to accept a future that offered only decline. She walked away from her career and poured herself into caregiving, advocacy, and an unrelenting search for answers. That search led her and her husband to a clinical trial for a drug that showed promise. Miles was enrolled. The treatment was effective. That drug—now known as Spinraza—went on to become the first-ever FDA-approved treatment for SMA. From that breakthrough moment, Nikki immersed herself in the world of rare disease advocacy. She began writing down everything she wished she had known at the beginning of their journey. With a deep desire to empower other rare moms, she wrote the book Rare Mamas: Empowering Strategies for Navigating Your Child's Rare Disease. Nikki continues to walk this road alongside her son, and alongside the millions of mothers who are parenting children with rare diseases. She has a deep passion for providing strategies, strength, support, and sisterhood to her fellow rare moms. In This Episode, You'll Learn: What Spinal Muscular Atrophy (SMA) is and how it affects children and families Nikki's emotional journey from diagnosis to advocacy How her son's participation in a clinical trial offered hope and insight The inspiration behind Rare Mamas and its empowering message Strategies for parents navigating rare disease diagnoses and complex healthcare systems The importance of building community and finding your voice as a caregiver How to balance hope for new treatments with the daily realities of care Resources:  Nikki's website that houses all her projects, RareMamas.com  Buy Nikki's book: Rare Mamas: Empowering Strategies for Navigating Your Child's Rare Listen to Nikki's podcast: Rare Mamas Rising Learn more about SMA via MedlinePlus Patient Empowerment Program, another podcast in our science podcast network Gene Pool Media, is hosted by one of the pharmacists that helped develop Spinraza, the first FDA approved treatment for SMA. Miles was part of the clinical trial.  Stay tuned for the next new episode of “It Happened To Me”! In the meantime, you can listen to our previous episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “It Happened To Me”.    “It Happened To Me” is created and hosted by Cathy Gildenhorn and Beth Glassman. DNA Today's Kira Dineen is our executive producer and marketing lead. Amanda Andreoli is our associate producer. Ashlyn Enokian is our graphic designer.   See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, ItHappenedToMePod.com. Questions/inquiries can be sent to ItHappenedToMePod@gmail.com.

Five years ago, we first spoke with Nikki McIntosh. In this episode, Nikki returns to share her journey as a mother of a child with spinal muscular atrophy (SMA) and the profound impact of clinical trials on her son's life. Miles is growing up and has started playing wheelchair tennis. Nikki shares the joy this brings to her. Nikki also discusses the emotional roller coaster of navigating rare diseases, the importance of community support, and her new book, 'Rare Mamas: Empowering Strategies for Navigating Your Child's Rare Disease.' The conversation and the book highlight resilience, advocacy, and the need for actionable strategies for parents facing similar challenges.https://raremamas.com

From a massive SIM farm takedown to dealing with supply chain attacks targeting npm, our news roundup provides context and commentary on a fresh crop of security news. We discuss exploits against Cisco firewalls and switches, a SonicWall firmware update to remove a rootkit targeting its SMA 100, and GitHub’s plans to harden npm packages.... Read more »

From a massive SIM farm takedown to dealing with supply chain attacks targeting npm, our news roundup provides context and commentary on a fresh crop of security news. We discuss exploits against Cisco firewalls and switches, a SonicWall firmware update to remove a rootkit targeting its SMA 100, and GitHub’s plans to harden npm packages.... Read more »

Kevin Horner with Charles Schwab highlights a scenario where the SPX can retreat to 6,500 if technicals can't hold the line. CoreWeave (CRWV) tested the 20-day SMA and bounced off the metric, though Kevin warns a slip below that can make short-term trading "dicey." He later points out Reddit's (RDDT) shooting star pattern that led to mass selling action, adding that it can slide another 20% from current levels if it fails a bear flag test.======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

A lively, unscripted listener Q&A episode with no set topic — just a flood of great questions. Don and Tom tackle everything from inheriting farmland to the hidden cost of medical inflation, tax-efficient short-term investments, Ameriprise conflicts of interest, fund turnover ratios, and a heartfelt tribute to the late Jonathan Clements, a true pioneer of rational investing journalism. Plenty of wit, warmth, and straight talk about money — plus a personal moment of honesty from Tom about life, loss, and gratitude. 0:04 Cold open: “A show with no topics” banter and weather humor 2:07 Angie from St. Paul: Inheriting farmland — hold or sell? 6:04 Anton from Spokane: Medflation's impact on Social Security COLA and Medicare premiums 10:45 Jason from Tigard: SPAXX vs. SGOV — which is better for short-term cash? 13:35 Ameriprise client: Should I use an SMA or fire my advisor? 18:41 Luke from Evans, GA: ETF turnover and what it really means 23:25 Tribute to Jonathan Clements — his life, legacy, and impact on index investing 27:10 Personal reflections, audience appreciation, and gratitude from Tom Learn more about your ad choices. Visit megaphone.fm/adchoices

Charles Schwab's Kevin Horner says the SPX's 20-day SMA can "very well" provide continued support for the index with "few and far between" breaks since April lows. In stock movers, Kevin points out a support range in Celsius (CELH) by widening the view in an 18-month chart. He later talks about the "intriguing" move in Lyft Inc. (LYFT) that opened the door for bulls.======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

Don and Tom tackle the “big three” global equity ETFs—Vanguard VT, Dimensional DFAW, and Avantis AVGE—breaking down their diversification, costs, risk/return assumptions, style tilts (small/value vs large/growth), and geographic/sector weights. They highlight how DFA and Avantis add microcaps and factor tilts that Vanguard's index omits, why fees are “pennies” but differences in construction matter, and why “rules-based” is more accurate than “active.” Listener questions cover lottery winnings (lump sum vs annuity), the collapse of Publishers Clearinghouse payouts, and Ameriprise's pricey SMA accounts. The theme: investing lives in the middle ground—balancing risk, cost, and logic. 0:04 Middle-dweller banter and show open 0:54 Why ETFs replaced mutual funds as the easy route 1:23 The “big three” global ETFs: VT, AVGE, DFAW 2:34 Which is “better”? Spoiler: none—or all 2:56 Diversification: DFAW 13,700 stocks vs VT's 10,000 4:00 Expense ratios: Vanguard's cost advantage 4:32 Risk/return projections and why they're guesses 6:22 Microcaps explain much of the differences 7:55 Why small/value stocks historically outperform 8:55 Style box breakdown: small vs large allocations 9:45 U.S. vs international exposure: “pandering portfolios” 10:57 Tech vs financials: sector allocations diverge 12:09 Recent performance snapshots, short vs long term 13:34 Index (VT), Factor (DFAW), Rules-based tilt (AVGE) 15:25 Long-term results: Avantis beats Vanguard despite higher fee 16:15 Risk/return symmetry: you could make a lot, lose a lot 16:45 Listener Q&A: $2B Powerball jackpot—lump sum or annuity? 18:01 Publishers Clearinghouse collapse leaves winners unpaid 21:07 Listener Q&A: Ameriprise SMA fees and pitfalls 23:48 Why Ameriprise's “nice” advisors are still costly Learn more about your ad choices. Visit megaphone.fm/adchoices

Pressure on markets has pushed the SPX closer to its 20-day SMA, which Kevin Green considers a critical level to hold bullish momentum. He also points to 100% tariffs on some imported drugs and, 25% tariffs on trucks, and 30% tariffs on furniture adding pressure for many stocks. There is progress on TikTok, however, as Kevin highlights the Trump-approved deal that links Oracle (ORCL) to the social media giant among other companies.======== Schwab Network ========Empowering every investor and trader, every market day.Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – / schwabnetwork Follow us on Facebook – / schwabnetwork Follow us on LinkedIn - / schwab-network About Schwab Network - https://schwabnetwork.com/about

In episode 153, host Kevin Schaefer talks with Annie Heathcote from Mazomanie, Wisconsin. Annie is a multi-business owner, social media influencer, author, and lifelong disability advocate whose life and work embody the belief that disability doesn't mean inability. Diagnosed with Spinal Muscular Atrophy (SMA) at just 13 months and in a wheelchair by age 2, she has dedicated her life to breaking barriers, championing accessibility, and inspiring others with her message of resilience and faith. Visit our website at www.smanewstoday.com Follow us: IG: instagram.com/smanewstoday Facebook: facebook.com/SMAnewstoday X: x.com/smanewstoday To take part in our ongoing discussions regarding SMA, please visit www.smanewstoday.com/forums

The US Secret Service raids a SIM farm in New York, EU airport disruptions were caused by ransomware, thieves steal gold nuggets from a French museum after a cyberattack and SonicWall releases a firmware update to remove SMA rootkits. Show notes Risky Bulletin: US raids SIM farm in New York

Standards set the foundation for any professional organization. The baseline for professionalism in the US Army is Army Regulation 670-1; Wear and Appearance of Army Uniforms and Insignia. This regulation dictates the standard for every Soldier, regardless of rank or position. AR 670-1 has long been a hot topic of discussion among Soldiers and leaders at every level; and too often left open to interpretation. Until now…At the direction of senior Army leadership, Army Directive 670-1 has been released to clarify these standards and provide shared understanding between Soldiers and leaders to know what ‘right' looks like.To explain the changes and how they will affect every member of the Army, Fran Racioppi sat down with Sergeant Major of the Army Mike Weimer, SGM Laurin Nabors and SGM Alex Kupratty. The SMA shares the “why” behind personal grooming standards and the importance of doing the little things that develop a culture of commitment from compliance. SGM Kupratty breaks down the definition of professional soldier from the experienced warriors of 75th Ranger Regiment to the new Privates of 4th Infantry Division. SGM Nabors provides the details on what's changing, when and how the new standards are expected to be enforced. She also shares her journey from an Army Reserve heavy equipment operator to the halls of the Pentagon. This episode is about redefining what it means to serve in the greatest fighting force the world has ever seen and why development of a war fighting culture starts with how a Soldier presents themself each and every day.Highlights0:00 Welcome to the Jedburgh Podcast3:26 Army Directive vs Regulation in 670-15:30 Why Now8:49 Closing Gaps12:55 Changes to 670-121:08 Why Standards Matter28:25 Analyzing Data29:42 Beards34:30 Preparing soldiers38:10 Active Guard Reserve44:30 Joining the Ranger Battalion49:42 The Grace Period50:33 Daily HabitsQuotes“Part of the problem is our process is too slow.”“The first thing I had to figure out is are they educated?”“Do they understand the standards as they are written?”“Once you are emplaced in a leadership position, that's where the commitment piece has to be rock solid.”"If you can't do the simple things I'm asking you to do, how are you going to do the hard things in combat?”“We had to come in and really define “What is military appearance?”“It's a direct reflection of your willingness to be compliant to a standard in your leaders.”“The why reinforces one uniformity.”“We're part of something bigger than all of us."“Really understanding the generational differences that exist is arguably the most challenging thing that I found as a senior leader in the Army.”“I don't think anybody knows what large scale combat will look like.”“The camaraderie that exists in that formation is unlike anything I've seen before.”“Leadership's not about 'What did I do here today?' It's 'What did I do for everyone else here to be successful?'"“You're only as good as the time you put in.”The Jedburgh Podcast is brought to you by University of Health & Performance, providing our Veterans world-class education and training as fitness and nutrition entrepreneurs.Follow the Jedburgh Podcast and the Green Beret Foundation on social media. Listen on your favorite podcast platform, read on our website, and watch the full video version on YouTube as we show why America must continue to lead from the front, no matter the challenge.

Kevin Green says the SPX shows signs of bullish momentum through technicals, particularly with levels currently hover above the 20 and 50-day SMA. He also notes an influx in calls on the options front adding confidence to the bull thesis. Kevin turns to the international front and explains why investors will want to keep their eyes on Chinese stocks. Then there's the VIX, as he talks about what it means for trading action today.======== Schwab Network ========Empowering every investor and trader, every market day. Subscribe to the Market Minute newsletter - https://schwabnetwork.com/subscribeDownload the iOS app - https://apps.apple.com/us/app/schwab-network/id1460719185Download the Amazon Fire Tv App - https://www.amazon.com/TD-Ameritrade-Network/dp/B07KRD76C7Watch on Sling - https://watch.sling.com/1/asset/191928615bd8d47686f94682aefaa007/watchWatch on Vizio - https://www.vizio.com/en/watchfreeplus-exploreWatch on DistroTV - https://www.distro.tv/live/schwab-network/Follow us on X – https://twitter.com/schwabnetworkFollow us on Facebook – https://www.facebook.com/schwabnetworkFollow us on LinkedIn - https://www.linkedin.com/company/schwab-network/ About Schwab Network - https://schwabnetwork.com/about

In the Who Should Worship Kālī? | Dakṣiṇa Kālī vs Smaśāna Kālī talk, we explained the technical term "jagadānanda" which describes the bliss of fullness. We argued that from the Kaula point of view, the goal is not transcendence but fullness; not freedom "from" the world but freedom "as" the world. And we pointed out how Kālī sādhanā is uniquely about embracing this non-dual totality of all things! The Absolute Reality is dynamic, ever-free Consciousness, my very own Self and the goal is to realize this in all things, as all things. Necessarily, this involves coming to terms with realities that the dualistic, conditioned and limited mind often rejects. "Who dares misery love: to him the Mother comes" etc. Then, in Kālī's Non-Duality of Radical Acceptance | vs. Classical Non-Duality we went in with some finer brush strokes to compare the view of Classical Advaita, which we termed the "path of absolute negation" with that of Tāntrik Advaita, or the Non-Duality of Kālĩ which we described as the "path of absolute acceptance". Both can lead to non-dual realization and yet who can deny that these might be different flavors of non-dual realization! The former path is fit for some while the latter suits the disposition of others and for many, the two paths are practiced sequentially, one after another. All this we discussed in last week's talk. Now, this week, we take up this topic yet again but using the Sāmkhyan idea of the gunas to show how Kālī sādhana (i.e Tāntrik non-duality) is unique and therefore for some people, uniquely disturbing. I make a case against transcendentalists, "sattva-only" oriented traditions! Originally, I had intended this lecture to be about staying safe and grounded in Kālī sādhanā or something along the lines of a PSA on kundalini emergencies/spiritual crisis but I spent so much time describing how Kālī sādhanā uniquely leads to destabilization that I never really got around to talking about techniques for grounding! We briefly mention a few towards the end but I suspect I'll want to develop these theme on safety more next week: stay tuned! Support the showLectures happen live every Monday at 7pm PST and Friday 10am PST and again Friday at 6pm PST.Use this link and I will see you there:https://www.zoom.us/j/7028380815For more videos, guided meditations and instruction and for access to our lecture library, visit me at:https://www.patreon.com/yogawithnishTo get in on the discussion and access various spiritual materials, join our Discord here: https://discord.gg/U8zKP8yMrM

Broadly speaking, there are to archetypical non-dual traditions, two very valid paths to bliss: The Non-Duality of Total Negation (Classical Advaita) & Kālī's Non-Duality of Total Acceptance (i.e Tāntrik Non-Duality or paramadvāya). Of course there are infinite shades of nuance and variation in between these two extremes. In this talk, we do a comparison of these two extreme models (or rather, flavor)s of non-dual Sādhanā, playing off of some ideas from last week's “Who Should Worship Kālī? | Dakṣiṇa Kālī vs Smaśāna Kālī” talk! This lecture is mostly a theoretical survey of the absolute state of realization which can anyone anywhere can attained through grace (i.e, sudden spontaneous insight) of course, but which is more likely to be a result of sincere spiritual practice! As for the practical side of this discussion, you might like to pair this talk with the What Do You Need To Start Worshipping Kālī & Practicing Tantra? lecture from two weeks ago! PS: you might find this lecture somewhat reminiscent of Who Created The World? | Vedanta vs Tantra and also Who or What is God? | Vedanta vs Tantra but we've certainly developed the ideas quite a bit since then! Support the showLectures happen live every Monday at 7pm PST and Friday 10am PST and again Friday at 6pm PST.Use this link and I will see you there:https://www.zoom.us/j/7028380815For more videos, guided meditations and instruction and for access to our lecture library, visit me at:https://www.patreon.com/yogawithnishTo get in on the discussion and access various spiritual materials, join our Discord here: https://discord.gg/U8zKP8yMrM

After watching What Does Kālī Want From You? | The Yoga of Grief & Fullness, Who Should Worship Kālī? | Dakṣiṇa Kālī vs Smaśāna Kālī and What Do You Need To Start Worshipping Kālī & Practicing Tantra? you might be starting to get the impression that Kālī pūjā and sādhana is (as Sri Ramakrishna himself put it) no joke! As such, to stay safe and to practice in a meaningful, gradual and integrated way, we have to discuss some foundations. After all, Mother Kālī is always standing on Śiva: isn't this a clue for us? To practice Kālī sādhanā, we should become like Śiva, that is to say, we should build our Kālī practice on top of some firm and stable Śaiva foundations! As such, in this class, which is the culmination of this year's śrāvana festivities, O walk you through more or less the entirety of śiva pūjā & sādhana with a special emphasis on the foundational mantras of our Tāntrik tradition, known as the pañca-Brahmā mantras from the Taittirīyāranyaka from Yajur Veda, the foundational Veda for Śaivism & Tantra: sadyojātaṁ prapadyāmi sadyojātāya vai namo namaḥbhave bhave nāti bhave bhavasva māṁ bhavodbhavāya namaḥI take refuge in the ever-fresh (newly born) Śiva, salutations again and again! Do not let me be born into mundane existence again and again with every birth! Become my very Being! Salutations to You, the source of all Becoming! oṁ sadyojātāya paschimavaktrāya namaḥSalutations to Sadyojāta, the Westward facing Śiva!vāmadevāya namo jyeṣṭhāya namaḥ śreṣṭhāyanamo rudrāya namaḥ kālāya namaḥkalavikaraṇāya namo balāya namobalavikaraṇāya namo balapramathanāya namaḥsarvabhūtadamanāya namo manonmanāya namaḥSalutations to Vāmadeva, the eldest, the supreme Rudra (howling one), to Time and Dynamism, to Strength, to the Transformer of Strength and Destroyer of Strength, to the One who Subdues All Beings, abiding beyond the mind! oṁ vāmadevāya uttaravaktrāya namaḥSalutations to Vāmadeva, the Northward facing Śiva!aghorebhyo'tha ghorebhyo aghoraghoretarebhyaḥsarvabḥyo śarvaḥ sarvebhyo namaste rudra rūpebhyaḥSalutations to the gentle forms, fierce forms and forms that are both gentle and fierce, salutations to all the forms of Rudra everywhere! oṁ aghorāya dakṣiṇavaktrāya namaḥSalutations to Aghora, the Southward facing Śiva!oṁ tatpuruṣāya vidmahe mahādevāya dhīmahitanno rudraḥ pracodayāt oṁMay that spirit, may that Great God, may that Rudra guide my intellect!oṁ tatpuruṣāya purvavaktrāya namaḥSalutations to Tatpuruṣa the Eastward facing Śiva!īśāna sarvavidyānāmīśvaraḥ sarvabhūtānāṁ brahmādipati brahmaṇo'dhipatirbrahmā śivo me astu sa eva sadāśiva oṁO Lord of all Knowledge, the Lord of all Beings, the Primordial Lord of Brahmā (and the other gods) and theLord of  Brāhmanas, may you Śiva be Brahmā for me. You are the eternally auspicious oṁoṁ īśānāya urdhvavaktrāya namaḥSalutations to īśāna the Upward facing Śiva!Support the showLectures happen live every Monday at 7pm PST and Friday 10am PST and again Friday at 6pm PST.Use this link and I will see you there:https://www.zoom.us/j/7028380815For more videos, guided meditations and instruction and for access to our lecture library, visit me at:https://www.patreon.com/yogawithnishTo get in on the discussion and access various spiritual materials, join our Discord here: https://discord.gg/U8zKP8yMrM

Gyzele Brown is a proud native of Greenville, MS, now residing in Cleveland, MS.  She is the owner and operator of Gyzele's Salon and Spa, where she's dedicated to not only transforming looks but also impacting lives through her work.  A graduate of Delta State University and Goshen Cosmetology School, Gyzele's journey began with a background in speech and hearing science — yet her passion for hair and beauty took center stage.  Beyond her career, Gyzele is a proud mother of three amazing children who all have spinal muscular atrophy, a rare genetic disease. Her journey is filled with both challenges and blessings, and she's here to encourage others, remind them of the power of faith, and show that even in tough times, you can keep going for your family and yourself.  Join us as Gyzele shares her inspiring journey, full of hope, and powerful life lessons about strength, faith, and the importance of never giving up. ​Spinal muscular atrophy (SMA) is a genetic disease that causes muscle weakness and wasting due to the degeneration of motor neurons. It's a progressive disease that can be fatal in severe forms. SMA is typically caused by mutations in the SMN1 gene, which is responsible for producing a protein vital for motor neuron health. The severity and age of onset vary, with different types of SMA categorized based on symptom onset and severity.   ​ Key aspects of SMA: Progressive Nature: SMA is a progressive disease, meaning the symptoms worsen over time.  Varied Severity: SMA is classified into types based on the age of onset and severity of symptoms.  Types of SMA: Type 1 (Infantile-onset): Most severe, symptoms appear at birth or within the first six months, and many affected individuals don't survive past early childhood.  Type 2 (Intermediate): Symptoms appear between 6 and 18 months, individuals can sit but not walk unaided, and life expectancy varies.  Type 3 (Juvenile-onset): Symptoms appear later in childhood, individuals can walk but may have difficulty, and life expectancy is generally normal.  Type 4 (Adult-onset): Rare, with symptoms appearing in adulthood and causing mild motor impairment.  Symptoms: Symptoms include muscle weakness, difficulty with movement (sitting, crawling, walking), breathing and swallowing problems, and skeletal abnormalities like scoliosis.  Diagnosis: Diagnosis often involves clinical evaluation, genetic testing, and sometimes neurological examinations.  Treatment: While there is no cure, treatments like gene therapy and medications can help manage symptoms, improve motor function, and increase survival time. Physical therapy, occupational therapy, and assistive devices are also important.  Genetic Basis: SMA is primarily caused by mutations or deletions in the SMN1 gene.  Motor Neuron Degeneration: The disease affects motor neurons, which control muscle movement, leading to muscle weakness and atrophy.   

It's the last Bumper Summer Best of 2025 an we have saved some of the most weird and wonderful QFTP's for all you Smas and Das! Throwback to The Twits, The Depositor and that time a bird shat in Rosie's mouth! We hope you've all had a great summer. Keep an eye on the SMA feed for more exciting additional content coming your way very soon! Learn more about your ad choices. Visit podcastchoices.com/adchoices

Check out the best podcast show notes on the internet at www.thelongterminvestor.com  -----  Mutual funds, ETFs, and SMAs all give you access to the market — but the way they handle taxes, costs, and control can lead to very different outcomes. In this episode, I break down how each vehicle works, where it shines, and when it falls short. If you've ever wondered which is best for your portfolio, this is the episode you'll want to hear. Listen now and learn: ► Why mutual funds can leave you paying for other investors' decisions — and how ETFs and SMAs solve that problem. ► The key differences between mutual funds, ETFs, and SMAs in terms of tax efficiency, cost, and customization. ► When an SMA makes sense (and when it doesn't) — including how tax-loss harvesting at the stock level creates “tax alpha.” ► The future of investing vehicles: why ETFs dominate flows, how SMAs are growing, and why mutual funds still matter in retirement plans. Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com). Disclosure: This content, which contains security-related opinions and/or information, is provided for informational purposes only and should not be relied upon in any manner as professional advice, or an endorsement of any practices, products or services. There can be no guarantees or assurances that the views expressed here will be applicable for any particular facts or circumstances, and should not be relied upon in any manner. You should consult your own advisers as to legal, business, tax, and other related matters concerning any investment. The commentary in this “post” (including any related blog, podcasts, videos, and social media) reflects the personal opinions, viewpoints, and analyses of the Plancorp LLC employees providing such comments, and should not be regarded the views of Plancorp LLC. or its respective affiliates or as a description of advisory services provided by Plancorp LLC or performance returns of any Plancorp LLC client. References to any securities or digital assets, or performance data, are for illustrative purposes only and do not constitute an investment recommendation or offer to provide investment advisory services. Charts and graphs provided within are for informational purposes solely and should not be relied upon when making any investment decision. Past performance is not indicative of future results. The content speaks only as of the date indicated. Any projections, estimates, forecasts, targets, prospects, and/or opinions expressed in these materials are subject to change without notice and may differ or be contrary to opinions expressed by others. Please see disclosures here.

It's early 2020… The SMA tour has been announced, and the Ramsey's are also writing the Shagged Married Annoyed Book! This Best of includes Becky Beef (a long distant relative) and news from friend of the podcast Jess the Paramedic! As well as this, Rosie reveals her Bingo calling past and Chris gets called out for mansplaining on song lyrics. There's some hanky panky involving a friends aunt, inappropriate foot rubbing and some burglar role play! Enjoy. Learn more about your ad choices. Visit podcastchoices.com/adchoices