Podcasts about Clinical

John Murray, Ian Dennis & Ali Bruce-Ball talk football, travel & language. They reflect on a dramatic finish to the Champions League league phase and discuss ideas for changing the format. Plus unintended pub and film names returns, as does Clash of the Commentators along with the Great Glossary of Football Commentary. Suggestions welcome on WhatsApp voicenotes to 08000 289 369 & emails to TCV@bbc.co.uk02:00 John's fall from grace 06:50 5 Live commentaries coming up 12:50 Champions League reflections 17:45 Does the format need changing? 21:00 Unintended pub and film names 31:50 Harry Maguire for England? 35:45 Clash of the Commentators 47:15 Great Glossary of Football Commentary5 Live / BBC Sounds commentaries: Sat 1500 Leeds v Arsenal, Sat 1500 Brighton v Everton on Sports Extram Sat 1730 Chelsea v West Ham, Sun 1400 Man Utd v Fulham , Sun 1400 Aston Villa v Brentford on Sports Extra, Sun 1400 Forest v Palace on Sports Extra 2, Sun 1630 Tottenham v Man City.Great Glossary of Football Commentary: DIVISION ONE Agricultural challenge, Back to square one, Bosman, Bullet header, Cruyff Turn, Cultured/educated left foot, Dead-ball specialist, Draught excluder, Elastico/flip-flap, False nine, Fox in the box, Giving the goalkeeper the eyes, Grub hunter, Head tennis, Hibs it, In a good moment, In behind, Magic of the FA Cup, The Maradona, Off their line, Olimpico, Onion bag, Panenka, Park the bus, Perfect hat-trick, Rabona, Roy of the Rovers stuff, Schmeichel-style, Scorpion kick, Spursy, Target man, Tiki-taka, Towering header, Trivela, Where the kookaburra sleeps, Where the owl sleeps, Where the spiders sleep.DIVISION TWO Back on the grass, Ball stays hit, Beaten all ends up, Blaze over the bar, Business end, Came down with snow on it, Catching practice, Camped in the opposition half, Cauldron atmosphere Coat is on a shoogly peg, Come back to haunt them, Corridor of uncertainty, Couldn't sort their feet out, Easy tap-in, Daisy-cutter, First cab off the rank, Giant-killing, Good leave, Half-turn, Has that in his locker, High wide and not very handsome, Hospital pass, Howler, In the dugout, In their pocket, Johnny on the spot, Leading the line, Needed no second invitation, Nice headache to have, Nutmeg, On their bike, One for the cameras, One for the purists, Played us off the park, Points to the spot, Prawn sandwich brigade, Purple patch, Put their laces through it, Reaches for their pocket, Rolls Royce, Root and branch review, Row Z, Screamer, Seats on the plane, Show across the bows, Slide-rule pass, Steal a march, Straight in the bread basket, Stramash, Taking one for the team, Telegraphed that pass, Tired legs, That's great… (football), Thunderous strike, Turns on a sixpence, Walk it in, We've got a cup tie on our hands.UNSORTED 2-0 is a dangerous score, After you Claude, All-Premier League affair, Aplomb, Bag/box of tricks, Brace, Brandished, Bread and butter, Breaking the deadlock, Bundled over the line, Champions elect / champions apparent, Clinical finish, Commentator's curse, Coupon buster, Denied by the woodwork, Draught excluder, Elimination line, Fellow countryman, Foot race, Formerly of this parish, Free hit, Goalkeepers' Union, Goalmouth scramble, Good touch for a big man, Honeymoon Period, In and around, In the shop window, Keeping ball under their spell, Keystone Cops defending, Languishing, Loitering with intent, Marching orders, Nestle in the bottom corner, Numbered derbies, Opposite number, PK for penalty-kick, Postage stamp, Put it in the mixer, Rasping shot, Red wine not white wine, Relegation six-pointer, Rooted at the bottom, Route One, Sending the goalkeeper the wrong way, Shooting boots, Sleeping giants, Slide rule pass, Small matter of, Spiders web, Stayed hit, Steepling, Stinging the palms, Stonewall penalty, Straight off the training ground, Taking one for the team, Team that likes to play football, Throw their cap on it, Thruppenny bit head / 50p head, Two good feet, Turning into a basketball match, Turning into a cricket score, Usher/Shepherd the ball out of play, Walking a disciplinary tightrope, Wand of a left foot, Wrap foot around it, Your De Bruynes, your Gundogans etc.

Episode Summary Cash-based clinics live and die by clear communication, confidence, and value. In this episode, Doc Danny breaks down four red flags that your staff clinician has a money mindset problem and how it quietly crushes conversions, plan-of-care adherence, retention, and clinic revenue. In This Episode, You'll Learn Why money mindset issues are common in healthcare and how they show up in cash-based care How staff clinicians unknowingly make affordability decisions for patients The damage caused by apologizing for pricing and losing authority Why downgrading plans without clinical justification creates hidden revenue loss and burnout How "made-up stories" about a patient's finances sabotage recommendations and outcomes What to coach your staff on so they sell clinically appropriate plans with confidence The 4 Signs Your Staff Clinician Has a Money Mindset Problem They decide what a patient can afford instead of what the patient needs. Making assumptions based on someone's job, car, or appearance leads to under-prescribing care and poor outcomes. Start with the diagnosis and prognosis, then let the patient decide. They apologize for pricing. If your clinician says "I know this is expensive," they've already surrendered authority. Your pricing should feel normal because the value is real. Confidence transfers. They downgrade plans without clinical justification. Selling a smaller package and stretching it out usually means more unpaid work between visits, slower progress, lower clinic revenue, and higher clinician burnout. Recommend the right plan first. They create stories about a patient's finances. "They have three kids, money must be tight" is not clinical reasoning. You don't know a patient's priorities, household income, or what they value most. Technology Spotlight Want your clinicians fully present with patients instead of clicking through notes? Try Claire free for 7 days and see how an AI scribe built for physical therapists can reduce documentation time and improve the patient experience. Key Takeaway Your clinician's job is to prescribe the plan that matches the diagnosis and prognosis, not to pre-negotiate on the patient's behalf. When staff confidence rises, conversions rise, retention rises, and the whole clinic scales faster. Free Resource Want to go from part-time to full-time in your cash practice with a clear plan? Join the free 5-Day Challenge. Connect Physical Therapy Biz PT Entrepreneur Podcast

In this episode of Excess Returns, we're joined again by Dan Rasmussen of Verdad Advisors for a wide-ranging conversation that challenges some of the most popular narratives in markets today. From private equity and private credit risks to AI-driven capital cycles and overlooked opportunities in biotech and international equities, Dan offers a deeply research-driven perspective on where investors may be misallocating capital and where future returns could emerge. Alongside Justin and special guest co-host Kai Wu, the discussion connects valuation, incentives, and innovation in a market environment shaped by concentration, leverage, and technological change.Main topics covered• Why private equity performance continues to disappoint and where the biggest structural risks are emerging• The growing stress in private credit and what rising bankruptcies signal for lower middle-market deals• Why democratizing private equity through 401ks, interval funds, and ETFs may create more problems than solutions• How AI CapEx is changing the economics of Big Tech and why asset-light models may be getting worse, not better• The case for diversifying away from U.S. concentration toward international markets and international small value• Why bubbles are often necessary for innovation and how to think about AI through that historical lens• How investors may be underestimating valuation and growth bankruptcy risk in the Mag 7• Why biotech is one of the hardest sectors to model and how Verdad rebuilt its framework from scratch• How intangible value, clinical trial data, specialist ownership, and peer momentum can improve biotech investing• What capital starvation, M&A dynamics, and global competition mean for biotech's future returnsTimestamps00:00 Introduction and market narratives02:20 Revisiting private equity risks and performance06:58 Private credit stress and bankruptcy signals10:58 Private equity in 401ks and interval fund risks14:52 Private assets in ETFs and liquidity concerns15:45 Why bubbles drive innovation and capital formation20:13 AI CapEx, Mag 7 concentration, and valuation risk25:24 International diversification and market leadership29:41 Why Verdad turned to biotech research37:13 Rebuilding biotech valuation and quality metrics44:26 Clinical trial data and peer momentum insights49:17 Portfolio construction and long-short biotech strategies51:00 Capital starvation, AI, and biotech's setup53:58 Research culture, humility, and evolving quant models

In this episode, discover innovative dermatology compounding formulations featuring methylene blue for anti-aging skincare. Clinical pharmacist Nat Jones discusses PCCA's USP-grade methylene and the need for quality. Methylene blue may play a role in collagen stimulation, hyaluronic acid production, and UV protection. Also, learn about bio-peptide cream bases, research on carbamazepine and plaque psoriasis as well as research on losartan and hypertrophic scars. Explore evidence-based topical treatments that may be appropriate for patients in compounding pharmacies. Perfect for pharmacists seeking advanced dermatological formulation strategies and cosmeceutical applications.   Learn more by visiting our blog:   Methylene Blue: Something Old and Something Blue   Working with Methylene Blue: Best Practices for Compounding and Cleanup   Methylene Blue: From Textile Dye to Potential Clinical Wonder  

If you work with preschoolers with autism and you care about spoken language outcomes, this episode matters. A lot. In today's episode of The Preschool SLP Podcast, we unpack the largest study to date examining why some autistic children do not develop spoken language, even after receiving high-quality, evidence-based early intervention. The takeaway is blunt: Motor imitation doesn't matter a little. It matters a lot. Inside this episode, we cover: Why one-third of autistic preschoolers in a large, multi-site study did not advance in spoken language despite receiving ~10 hours/week of evidence-based intervention How motor imitation emerged as a key distinguishing factor between children who advanced in speech and those who did not What neuroscience tells us about mirror neurons, empathy, perspective-taking, and speech development Why speech develops from the inside out: core → proximal → distal → speech. And, what happens when we skip the body and go straight to the mouth How motor imitation supports: Entry into peer play Social communication Speech motor planning and execution Prefrontal–cerebellar connectivity Why this research gives us a “crystal ball”—not to maintain the status quo, but to do something different earlier You can't build speech on a system that can't yet support posture, movement, imitation, and motor planning. If motor imitation is weak, speech outcomes are at risk, pretending otherwise doesn't help children. Clinical bottom line: If a child presents with: Severe autism presentation Limited or absent spoken language Poor motor imitation Then motor imitation must be intentionally built into intervention, alongside AAC, multimodal cueing, movement-based learning, and robust communication supports. This episode challenges us to stop treating mouths—and start treating children.

Clinical trial complexity is rising with more procedures, endpoints, and technology, yet sites are turning these pressures into pathways for improvement. In this episode of WCG Talks Trials, host Jenna Goeller sits down with Trevor Cole to unpack practical ways research sites sustain readiness, build resilience, and spark innovation amid frequent protocol amendments and technology overload. Together, they explore what's changing on the ground and how sites are responding with stronger feasibility reviews, capacity planning, streamlined protocol advocacy, and risk‑proportionate oversight – all grounded in Quality by Design and the updated ICH E6(R3) guidance.Listeners will hear data‑driven insights on:The operational ripple effects of complexity, including resource strain, rework from amendments, and tech support burdens, and what's working to reduce them.Day‑to‑day applications of risk‑based quality management, data governance, and proportionality to protect participant safety and data integrity.Culture and maturity for empowering teams, mapping processes before SOPs, continuous training, Correction and Preventive Action (CAPA) discipline, and knowledge sharing across silos.How sponsors and CROs can better support sites through integrated technology, protocol simplification, early collaboration, and transparent communications.Turning complexity into growth by investing in people and processes, using fit‑for‑purpose tech (including selective AI use), and engaging local communities.Speakers:Jenna Goeller, Associate Director, Clinical Trial Insights & Analytics, WCGTrevor Cole, Program Director, Clinical Solutions & Partnering, WCG

Send us a textThis week we're heading into week three of the challenge, and I want to talk about something subtle that can quietly make everything feel harder—your energy, your focus, your patience, even your progress. I've been thinking a lot about how often we push through discomfort without ever stopping to ask why it's there. And how, as women who manage full lives and full calendars, we're incredibly skilled at overriding ourselves instead of listening.In today's shorty episode, I invite you to slow down just enough to notice what your body has been trying to tell you all along. This is about strength without force, awareness without judgment, and learning how to trust yourself again in a world that constantly asks you not to. If you've ever felt like something was “off” but couldn't quite put your finger on it, this conversation is for you.Quote of the Week:“The body is your instrument. Learn to play it well.” — Martha GrahamReferencesSkypala, I. J., & Venter, C. (2019). Food intolerance: Clinical perspectives and management. Nutrients, 11(7), 1684. https://doi.org/10.3390/nu11071684Turner, P. J., & Campbell, D. E. (2019). Epidemiology of food allergy. Journal of Allergy and Clinical Immunology, 143(1), 37–44. https://doi.org/10.1016/j.jaci.2018.11.003Fletcher, J., & Adolphus, K. (2021). Food intolerance and mental health: Associations with anxiety and depression. Nutrients, 13(12), 4386. https://doi.org/10.3390/nu13124386Phillips, C. M., Chen, L. W., Heude, B., Bernard, J. Y., Harvey, N. C., Duijts, L., … Godfrey, K. M. (2019). Dietary inflammatory index and metabolic health. Journal of Clinical Endocrinology & Metabolism, 104(12), 6118–6128. https://doi.org/10.1210/jc.2019-00294Esposito, K., Kastorini, C. M., Panagiotakos, D. B., & Giugliano, D. (2011). Mediterranean diet and metabolic syndrome. Journal of the American College of Cardiology, 57(11), 1299–1313. https://doi.org/10.1016/j.jacc.2010.09.073Hotamisligil, G. S. (2006). Inflammation and metabolic disorders. Nature, 444, 860–867. https://doi.org/10.1038/nature05485Saltiel, A. R., & Olefsky, J. M. (2017). Inflammatory mechanisms linking obesity and metabolic disease. Journal of Clinical Investigation, 127(1), 1–4. https://doi.org/10.1172/JCI92035Oddy, W. H., Allen, K. L., Trapp, G. S., Ambrosini, G. L., Black, L. J., Huang, R. C., … Mori, T. A. (2018). Dietary inflammatory index and mental health. British Journal of Nutrition, 119(8), 1–10. https://doi.org/10.1017/S0007114518000218 Let's go, let's get it done. Get more information at: http://projectweightloss.org

In this episode of the Innovations and Clinical Implementation podcast recorded at LongevityFest 2025, host Dr. Lexi Gonzales discusses the future of scalable healthcare with Dr. Jeff Gladd—the Chief Medical Officer at Fullscript and a practicing integrative physician—and Ben Walters, the Head of Journeys at Fullscript. The conversation centers on Fullscript's evolution into a "Whole Person Care" engine designed to alleviate administrative burden by launching **Journeys**, a new platform that aggregates fragmented patient contexts like intake forms, historical labs, and wearables into "four clean walls" to facilitate true personalization. The guests explain how embedding AI directly into the clinical workflow allows practitioners to reduce the time spent on lab interpretation and plan creation from 45 minutes to under seven minutes, effectively allowing them to "5x" their patient capacity while utilizing tools like the PROM 10 framework to objectively validate clinical outcomes. For access to episode resources: https://sites.google.com/ovationlab.com/innovationsinclinicalimplement/home

In the first video, we talked about the Metabolic Trinity. But why hasn't your doctor told you about it? In this video, we show the flaws in modern medical testing that make chronic illness invisible. Using three clinical studies, we explain why doctors check your blood instead of your tissues. We also look at why they don't test your actual energy levels. You'll learn about the "cellular trash" (MMWP) that makes you feel sick every day—and why your doctor never looks for it. This is why the medical system struggles to fix chronic illness, and why you can't wait for permission to start healing your own body.**Scientific References:***   *Dynamics of Basal Metabolic Rate During Absolute (Dry) Fasting* - Shows the 14% energy drop that blood tests miss.*   *Content of Medium Molecular Weight Peptides During Absolute Fasting* - Explains the cellular trash that doctors don't measure.*   *Clinical and Laboratory Criteria for Assessing Severity of Patients' Conditions* - Shows the gap between how patients feel and what medical tests show.**Helpful Resources:***   Dry Fasting Club: https://dryfastingclub.com*   The Scorch Protocol Hub: https://dry-fasting-club.github.io/scorch-protocol/index.html**Medical Disclaimer:**The content in this video is for educational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have heard in this video.

Clinical psychologist and parenting expert Dr. John Duffy joins Wendy Snyder, filling in for Lisa Dent, to discuss how a period of ‘national trauma’ is affecting the mental health of the country.

Today's episode is about clinical genetic services. In the first segment, Khalida talks to authors Courtney and Jade about retention of patient-facing genetic counselors and how generational age and work environment influence retention. For the second segment, Khalida chats with Dr. Ba-Jaj about telegenetics in India, reviewing data from 3 years and almost 1000 cases!     Segment 1: Factors influencing retention of patient-facing genetic counselors: Role of generational age and work environment Courtney Schroeder, MS, LCGC is an oncology genetic counselor at Indiana University Health. She received her BS in Psychology and Biology from the University of Dayton and her MS in Genetic Counseling from the University of North Carolina Greensboro. Courtney primarily works with the Precision Genomics team at IU Health. She also manages the Hereditary Renal and Prostate Cancer Clinic, which she established through a grant-funded project.   Jade McIntyre, MS, LCGC is a 2025 graduate of Indiana University Genetic Counseling Program. She is currently working as a genetic counselor in the Medical and Molecular Genetics Department at Indiana University Health. Jade is grateful for the opportunity to share the findings from her graduate student research that was published in July 2025.   In this segment we discuss: - This episode explores factors influencing retention of patient-facing genetic counselors. - The study highlights flexibility, autonomy, and experience as key drivers of retention. - Results show higher retention among older, more experienced counselors. - The discussion emphasizes employer strategies to improve workforce retention.   Segment 2: Telegenetics in India: A 3-year review of 938 appointments and patient–clinician perspectives   Dr Shruti Bajaj completed her MBBS and MD Pediatrics from Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Mumbai. She subsequently pursued a Fellowship in Clinical Genetics, accredited by Maharashtra University of Health Sciences, from Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Mumbai. Thereafter, Dr. Shruti Bajaj amassed vast clinical experience as an Assistant Professor in the busy Department of Pediatrics and Clinical Genetics at Seth Gordhandas Sunderdas Medical College and King Edward Memorial Hospital, Mumbai, for five years (2013- 2017). She has to her credit a short observership and training in Clinical & Laboratory Genetics from Kasturba Medical College, Manipal. She has additionally been trained through multiple short modules in different subspecialities of Clinical Genetics from prestigious centres across the country and the world. Some of these include the 'Cancer genetic counseling' course from Tata Memorial Hospital, Mumbai and the challenging 'Skeletal dysplasia' course from Lausanne, Switzerland. Dr Shruti Bajaj is the Founder and Director of The Purple Gene Clinic, which she established in 2017. The Purple Gene Clinic provides cares to patients across the country, and is one of the busiest and most trustworthy Genetic Clinics in India. Despite a demanding and busy practice, Dr Shruti Bajaj obtained the prestigious International Masters Degree in Neurometabolism and Cell Biology, from SJD Barcelona's Children Hospital, University of Barcelona, in 2024. During this course, Dr. Bajaj was awarded the prestigious International Travel Scholarship for both 2023 and 2024, after her submitted clinical cases were selected as the best amongst all applications, highlighting her exceptional clinical acumen and dedication. As a testimony to her passion for academics, Dr Bajaj has numerous national and international publications, as well as chapters in leading textbooks, to her credit. Dr Bajaj's innate compassion and passion for social services led her to establish a support group for individuals with Down syndrome, called PEHEL, in Mumbai in 2018. She also runs a charitable OPD at The Purple Gene Clinic, called Shantidevi Gupta Charitable OPD, in the loving memory of her late grandmother. Social media handles: Linkedin profile name: Dr Shruti Bajaj (Agarwal)  In this segment we discuss: - How tele-genetics improves access to genetic care across India. - When pure vs hybrid telemedicine works best for diagnosis. - Patient cost and time savings alongside clinician-reported challenges. - Scalable lessons for implementing tele-genetics in resource-limited settings.   Would you like to nominate a JoGC article to be featured in the show? If so, please fill out this nomination submission form here. Multiple entries are encouraged including articles where you, your colleagues, or your friends are authors.   Stay tuned for the next new episode of DNA Dialogues! In the meantime, listen to all our episodes Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Dialogues”.    For more information about this episode visit dnadialogues.podbean.com, where you can also stream all episodes of the show. Check out the Journal of Genetic Counseling here for articles featured in this episode and others.    Any questions, episode ideas, guest pitches, or comments can be sent into DNADialoguesPodcast@gmail.com.    DNA Dialogues' team includes Jehannine Austin, Naomi Wagner, Khalida Liaquat, Kate Wilson and DNA Today's Kira Dineen. Our logo was designed by Ashlyn Enokian. Our current intern is Stephanie Schofield.

Last year, the National Institutes of Health drastically cut funding for medical research. This disrupted the work of academics and researchers across the country. Clinical trials and scientific projects were cancelled, and funding for ongoing research was revoked. This meant big cuts in funding to research institutions here in Connecticut. UConn lost $41 million from research grant terminations and unexpected non-renewals. Today, we hear how these cuts are impacting research institutions in our state and the future of science. GUESTS: Rob Stein: Correspondent and Senior Editor, on NPR’s Science Desk Evan Morris: Professor of Radiology and Biomedical Imaging and of Biomedical Engineering at Yale School of Medicine Diane Owens: mother of a pediatric patient with neurofibromatosis Support the show: http://wnpr.org/donateSee omnystudio.com/listener for privacy information.

At CES in Las Vegas,Meredith Perry, Co-Founder and CEO, and Dr. David Wang, Co-Founder and CTO of Elemind  talk about how their wearable sleep headband uses real-time brainwave monitoring and precisely timed acoustic stimulation to help users fall asleep faster. By "noise-canceling" wakeful brainwaves, the device calms racing thoughts without drugs. Chuck had a chance to try it out and discusses his positive experience in spite of a noisy, distracting environment.  Show Notes: Chapters: • [0:03] Introduction to EleMind and CES demo • [0:40] How acoustic neuromodulation works • [1:20] The neuroscience behind falling asleep faster • [2:27] First-hand sleep experience and impressions • [4:46] Clinical validation and future applications • [7:22] Why sleep is foundational to overall health • [8:03] Pricing, availability, and closing thoughts Support:      Become a MacVoices Patron on Patreon      http://patreon.com/macvoices      Enjoy this episode? Make a one-time donation with PayPal Connect:      Web:      http://macvoices.com      Twitter:      http://www.twitter.com/chuckjoiner      http://www.twitter.com/macvoices      Mastodon:      https://mastodon.cloud/@chuckjoiner      Facebook:      http://www.facebook.com/chuck.joiner      MacVoices Page on Facebook:      http://www.facebook.com/macvoices/      MacVoices Group on Facebook:      http://www.facebook.com/groups/macvoice      LinkedIn:      https://www.linkedin.com/in/chuckjoiner/      Instagram:      https://www.instagram.com/chuckjoiner/ Subscribe:      Audio in iTunes      Video in iTunes      Subscribe manually via iTunes or any podcatcher:      Audio: http://www.macvoices.com/rss/macvoicesrss      Video: http://www.macvoices.com/rss/macvoicesvideorss

In this episode of the Smarter Not Harder Podcast, Ryan Carter joins Dr. Scott Sherr for a refreshingly real, honest, and grounded conversation about what's broken in the "biohacking" and health optimization world — and how to fix it. Ryan, a UK-based remote health practitioner, shares his journey from extreme protocols and burnout to balanced clinical systems that support long-term health. From redox before detox to seasonal eating, mold, light, water, and remote testing, this is the practitioner's perspective you rarely hear. Join us as we explore: • The top 5 health mistakes smart people still make   • Redox before detox: why energy must come first   • The dangers of extreme tribes and supplement obsession   • Clinical pearls for mold, light, and remote health testing This episode is for you if: • You're overwhelmed by protocols, labs, and conflicting health advice   • You've tried everything but still feel stuck or exhausted   • You're a clinician building an online or remote practice   • You want smarter, not harder ways to test, treat, and live You can also find this episode on…YouTube: https://youtu.be/PdkzQmQMMdU Find more from Ryan Carter:   Website: https://www.livevitae.com Instagram: https://www.instagram.com/livevitae LinkedIn: https://www.linkedin.com/in/livevitae/ Find more from Smarter Not Harder:   Website: https://troscriptions.com/blogs/podcast?utm_source=youtube&utm_medium=video&utm_campaign=snh_podcast_guest_episode_2025_10&utm_content=podcast_asset Instagram: https://instagram.com/troscriptions/ HOMeHOPe Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Get 10% Off your purchase of the Clinical Metabolomics module with code PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase with code POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of The Therapy Show, I chat with Ann Mac Prevost, a licensed professional counselor who specializes in teen anxiety. Ann Mac dives into how anxiety shows up in today's teens, why it's more prevalent than ever, and how parents and therapists can help teens manage it effectively. We also explore the role of family systems, the impact of social media, and practical tools that support emotional growth in adolescents. In this episode, we cover: The most common anxiety presentations in teens today Why COVID and smartphones have intensified anxiety in adolescents How to know when anxiety crosses from "normal" to "problematic" Tips for therapists working with teens and their families The importance of involving parents in the therapeutic process Helpful frameworks for validating emotions while promoting behavior change Practical CBT and exposure strategies that teens can actually use Whether you're a therapist, parent, or just curious about teen mental health, this conversation is packed with relatable insights and tools you can use right away.  Connect with Ann Mac. Links mentioned:

Disease accelerates years in a month. Cancer cells reveal which patients might be most impacted by metastasis - a diagnosis invisible on Earth. Single crystals heal themselves through mechanisms we can't explain. These aren't projections. They're validated results from 2022-2025 that made 40-year NASA veterans say they'd never seen anything like it.The economics flipped. Merck flew Keytruda 30 days, discovered a crystal form missed in a decade of labs - $20B/year by 2030, exceeding SpaceX's entire revenue. The thesis: Two paths to space affordability: cut launch costs 10x AND multiply payload value 1,000x. Do what Earth cannot do at any price.Paradigm Shifts:

In this episode, Dr. Cameron Bearder shares four of his biggest clinical takeaways from 2025. Each one is rooted in different areas of the clinical practice and aspects of day-to-day insights from the entire year.Contact Dr. Bearder:Clinical Practice - Keystone Upper Cervical Spine ClinicInstagram - @DrBearderLinkedIn - Dr. Cameron Bearder

“If we want to reach those societies or reach those populations, we definitely need to have others' blended approach of having both the clinic and the community organizations working together.”This episode kicks off Season 5 of the HPP Podcast and showcases the work of Dr. Sujha Subramanian, author of “Role of Community–Clinical Partnerships to Promote CancerScreening: Lessons Learned From the National Breast and Cervical Cancer Early Detection Program.” Dr. Subramanian shares how her team's work with external partners encourages and facilitates screenings for breast and cervicalcancer across multiple sites across the United States of America. The study's findings and best practices for collaboration and partnerships are explored in this episode.This episode references the article “Role of Community–Clinical Partnerships to Promote Cancer Screening: Lessons Learned From the National Breast and Cervical Cancer Early Detection Program” by Sujha Subramanian and colleagues.

"Your Own AI Assistant: Personalized, Private, and Built for Clinical Thinking." From ASRA Pain Medicine News, November 2025. See the original article at www.asra.com/november25news for figures and references. This material is copyrighted. Support the show

In this episode of the Very Clinical podcast, Zach and Kevin explore the evolution of social media within the dental profession, tracing the landscape from the early days of message boards like Dentaltown to the current era of Facebook groups, Reddit, and X. The hosts reflect on their personal experiences as digital observers and participants, discussing the culture of online communities—ranging from the valuable exchange of clinical tips to the unfortunate prevalence of "dunking" and trolling. They wrap up the conversation by sharing their favorite positive resources for dental content, including specific Instagram accounts and YouTube channels that offer genuine educational value. Join the Very Clinical Facebook group!  Join the Very Dental Facebook Group using one of these passwords: Timmerman, Bioclear, Hornbrook, Gary, McWethy, Crazy, Papa Randy, or Lipscomb!  The Very Dental Podcast network is and will remain free to download. If you'd like to support the shows you love at Very Dental then show a little love to the people that support us! I'm a big fan of the Bioclear Method! I think you should give it a try and I've got a great offer to help you get on board! Use the exclusive Very Dental Podcast code VERYDENTAL8TON for 15% OFF your total Bioclear purchase, including Core Anterior and Posterior Four day courses, Black Triangle Certification, and all Bioclear products. Crazy Dental has everything you need from cotton rolls to equipment and everything in between and the best prices you'll find anywhere! If you head over to verydentalpodcast.com/crazy and use coupon code "VERYSHIP" you'll get free shipping on your order! Go save yourself some money and support the show all at the same time! The Wonderist Agency is basically a one stop shop for marketing your practice and your brand. From logo redesign to a full service marketing plan, the folks at Wonderist have you covered! Go check them out at verydentalpodcast.com/wonderist! Enova Illumination makes the very best in loupes and headlights, including their new ergonomic angled prism loupes! They also distribute loupe mounted cameras and even the amazing line of Zumax microscopes! If you want to help out the podcast while upping your magnification and headlight game, you need to head over to verydentalpodcast.com/enova to see their whole line of products! CAD-Ray offers the best service on a wide variety of digital scanners, printers, mills and even  their very own browser based design software, Clinux! Al literally just bought (and is still waiting for delivery) of the new Elf scanner from Shining 3D and CAD-Ray helped make it happen! CAD-Ray has been a huge supporter of the Very Dental Podcast Network and I can tell you that you'll get no better service on everything digital dentistry than the folks from CAD-Ray. Go check them out at verydentalpodcast.com/CADRay!

On this week’s episode, we’re continuing our Guidelines Series exploring the 2022 ESC/ERS Guidelines for the diagnosis and treatment of Pulmonary Hypertension. If you missed our first episode in the series, give it a listen to hear about the most recent recommendations regarding Pulmonary Hypertension definitions, screening, and diagnostics. Today, we’re talking about the next steps after diagnosis. Specifically, we’ll be discussing risk stratification, establishing treatment goals, and metrics for re-evaluation. We’ll additionally introduce the mainstays of pharmacologic therapy for Pulmonary Hypertension. Meet Our Co-Hosts Rupali Sood  grew up in Las Vegas, Nevada and made her way over to Baltimore for medical school at Johns Hopkins. She then completed her internal medicine residency training at Massachusetts General Hospital before returning back to Johns Hopkins, where she is currently a pulmonary and critical care medicine fellow. Rupali’s interests include interstitial lung disease, particularly as related to oncologic drugs, and bedside medical education. Tom Di Vitantonio  is originally from New Jersey and attended medical school at Rutgers, New Jersey Medical School in Newark. He then completed his internal medicine residency at Weill Cornell, where he also served as a chief resident. He currently is a pulmonary and critical care medicine fellow at Johns Hopkins, and he’s passionate about caring for critically ill patients, how we approach the management of pulmonary embolism, and also about medical education of trainees to help them be more confident and patient centered. Key Learning Points 1) Episode Roadmap How to set treatment goals, assess symptom burden, and risk-stratify patients with suspected/confirmed pulmonary arterial hypertension (PAH). What tools to use to re-evaluate patients on treatment Intro to major PAH medication classes and how they map to pathways. 2) Case-based diagnostic reasoning Patient: 37-year-old woman with exertional dyspnea, mild edema, abnormal echo, telangiectasias + epistaxis → raises suspicion for HHT (hereditary hemorrhagic telangiectasia) and/or early connective tissue disease. Key reasoning move: start broad (Groups 2–5) and narrow using history/exam/testing. In a young patient without obvious left heart or lung disease, think more about Group 1 PAH (idiopathic/heritable/associated). HHT teaching point: HHT can cause PH in more than one way: More common: high-output PH from AVMs (often hepatic/pulmonary) Rare (1–2% mentioned): true PAH phenotype (vascular remodeling; associated with ALK1 in some patients), behaving like Group 1 PAH. 3) Functional class assessment WHO Functional Class: Class I: no symptoms with ordinary activity, only with exertion Class II: symptoms with ordinary activity Class III: symptoms with less-than-ordinary activity (can't do usual chores/shopping without dyspnea) Class IV: symptoms at rest Practical bedside tip they give: Ask if the patient can walk at their own pace or keep up with a similar-age peer/partner. If not, think Class II (or worse). 4) Risk stratification at diagnosis: why, how, and which tools Big principle: treatment choices are driven by risk, and the goal is to move patients to low-risk quickly. ESC/ERS approach at diagnosis (as described): Use a 3-strata model predicting 1-year mortality: Low: 20% ESC/ERS risk assessment variables (10 domains discussed): Clinical progression, signs of right heart failure, syncope WHO FC Biomarkers (NT-proBNP) Exercise capacity (6MWD) Hemodynamics Imaging (echo; sometimes cardiac MRI) CPET (peak VO₂; VE/VCO₂ slope) They note: even if you don't have everything, the calculator can still be useful with ≥3 variables. REVEAL 2.0: Builds on similar core variables but adds further patient context (demographics, renal function, BP, DLCO, etc.) Case result: both tools put her in intermediate risk (ESC/ERS ~1.6; REVEAL 2.0 score 8), underscoring that mild symptoms can still equal meaningful mortality risk. 5) Treatment goals and follow-up philosophy What they explicitly prioritize: Help patients feel better, live longer, and stay out of the hospital Use risk tools to communicate prognosis and to track improvement Reassess frequently (they mention ~every 3 months early on) until low risk is achieved “Time-to-low-risk” is an important treatment goal Also emphasized: The diagnosis is psychologically heavy; patients need clear counseling, reassurance about the plan, and connection to support groups. 6) Medication classes for the treatment of PAH Nitric oxide–cGMP pathway PDE5 inhibitors: sildenafil, tadalafil Soluble guanylate cyclase stimulator: riociguat Important safety point: don't combine PDE5 inhibitors with riociguat (risk of significant hypotension/hemodynamic effects) Endothelin receptor antagonists (ERAs) “-sentan” drugs: bosentan (less used due to side effects/interactions), ambrisentan, macitentan Teratogenicity emphasized Hepatotoxicity that requires LFT monitoring Can cause fluid retention and peripheral edema Prostacyclin pathway Prostacyclin analogs/agonists: Epoprostenol (potent; short half-life; IV administration) Treprostinil (IV/SubQ/oral/inhaled options) Selexipag (oral prostacyclin receptor agonist) 7) Sotatercept (post-guidelines) They note sotatercept wasn't in 2022 ESC/ERS but is now “a game changer” in practice: Mechanism: ligand trap affecting TGF-β signaling / remodeling biology Positioned as potentially more disease-modifying than pure vasodilators Still evolving: where to place it earlier vs later in regimens is an active question in the field 8) How risk category maps to initial treatment intensity General approach they outline: High risk at diagnosis: parenteral prostacyclin (IV/SubQ) strongly favored, often aggressive early Intermediate risk: at least dual oral therapy (typically PDE5i + ERA); escalate if not achieving low risk Low risk: at least one oral agent; many still use dual oral depending on etiology/trajectory For the case: intermediate-risk → start dual oral therapy (they mention tadalafil + ambrisentan as a typical choice), reassess in ~3 months; add a third agent (e.g., selexipag/prostacyclin pathway) if not low risk.  References and Further Reading Humbert M, Kovacs G, Hoeper MM, Badagliacca R, Berger RMF, Brida M, Carlsen J, Coats AJS, Escribano-Subias P, Ferrari P, Ferreira DS, Ghofrani HA, Giannakoulas G, Kiely DG, Mayer E, Meszaros G, Nagavci B, Olsson KM, Pepke-Zaba J, Quint JK, Rådegran G, Simonneau G, Sitbon O, Tonia T, Toshner M, Vachiery JL, Vonk Noordegraaf A, Delcroix M, Rosenkranz S; ESC/ERS Scientific Document Group. 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Heart J. 2022 Oct 11;43(38):3618-3731. doi: 10.1093/eurheartj/ehac237. Erratum in: Eur Heart J. 2023 Apr 17;44(15):1312. doi: 10.1093/eurheartj/ehad005. PMID: 36017548. Condon DF, Nickel NP, Anderson R, Mirza S, de Jesus Perez VA. The 6th World Symposium on Pulmonary Hypertension: what’s old is new. F1000Res. 2019 Jun 19;8:F1000 Faculty Rev-888. doi: 10.12688/f1000research.18811.1. PMID: 31249672; PMCID: PMC6584967. Maron BA. Revised Definition of Pulmonary Hypertension and Approach to Management: A Clinical Primer. J Am Heart Assoc. 2023 Apr 18;12(8):e029024. doi: 10.1161/JAHA.122.029024. Epub 2023 Apr 7. PMID: 37026538; PMCID: PMC10227272. Hoeper MM, Badesch DB, Ghofrani HA, Gibbs JSR, Gomberg-Maitland M, McLaughlin VV, Preston IR, Souza R, Waxman AB, Grünig E, Kopeć G, Meyer G, Olsson KM, Rosenkranz S, Xu Y, Miller B, Fowler M, Butler J, Koglin J, de Oliveira Pena J, Humbert M; STELLAR Trial Investigators. Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension. N Engl J Med. 2023 Apr 20;388(16):1478-1490. doi: 10.1056/NEJMoa2213558. Epub 2023 Mar 6. PMID: 36877098. Ruopp NF, Cockrill BA. Diagnosis and Treatment of Pulmonary Arterial Hypertension: A Review. JAMA. 2022 Apr 12;327(14):1379-1391. doi: 10.1001/jama.2022.4402. Erratum in: JAMA. 2022 Sep 6;328(9):892. doi: 10.1001/jama.2022.13696. PMID: 35412560.

In this episode of the Science of Skin podcast, Dr. Ted Lain interviews Dr. Matt Zirwas, a leading expert in dermatology, focusing on the latest advancements in treatments for atopic dermatitis and psoriasis. They discuss the potential of new drugs targeting the OX40 pathway, innovative drug delivery methods, and the emergence of highly effective oral therapies for psoriasis. The conversation highlights the evolving landscape of dermatological treatments and the exciting prospects for long-term patient outcomes. In this conversation, Dr. Zirwas and Dr. Lain discuss various dermatological treatments, focusing on drug administration, bioavailability, and the efficacy of new medications for conditions like hidradenitis suppurativa and chronic spontaneous urticaria. They explore the implications of PDE4 inhibitors, the challenges of assessing treatment outcomes, and the importance of pain management in patient care. The discussion highlights the evolving landscape of dermatology and the significance of clinical trials in advancing treatment options. To watch this and other episodes, be sure to check out our YouTube page Takeaways: New drugs targeting the OX40 pathway may revolutionize treatment for atopic dermatitis.Innovative drug delivery methods could lead to less frequent dosing for patients.The potential for long-term remission in atopic dermatitis is an exciting prospect.Adverse events in new drugs may correlate with better efficacy.Oral therapies for psoriasis are emerging as a new class of effective treatments.The efficacy of new oral drugs may surpass traditional biologics.The importance of understanding pharmacokinetics in drug efficacy is highlighted.The development of advanced systemic therapies is changing the landscape of dermatology.The future of psoriasis treatment may include drugs that effectively target both skin and joint disease. Drug bioavailability is significantly affected by food intake.PDE4 inhibitors show promise in improving various conditions.Cognitive benefits have been observed with PDE4 inhibitors.Pain management is a critical endpoint in HS treatment.Assessing HS severity is challenging for investigators.New treatments are emerging for chronic spontaneous urticaria.Patient satisfaction is essential in evaluating treatment success.Innovative drugs are changing the landscape of dermatology.Clinical trials are crucial for advancing treatment options.Understanding patient needs is key to effective care. Disclaimer: This podcast is not intended to provide diagnosis, treatment, or medical advice. Content provided in this podcast is for educational purposes only. Please consult with a physician regarding any health-related diagnosis or treatment. See omnystudio.com/listener for privacy information.

In this AJNR Fellows' Journal Club article summary, Dr. Francis Deng and Dr. Amir Khadivi discuss the article by Proner et al., "Impact of Clinical and Radiologic Factors on CTP Timing in Acute Ischemic Stroke." They discuss the authors' findings that cardiac arrhythmias and older age are independent predictors of nondiagnostic CTP exams. Specifically, these factors often lead to the truncation of reference vessel time-attenuation curves that fail to reach equilibrium within a 45-second acquisition window.

Today, I'm joined by Dr. Muthu Alagappan, founder & CEO of Counsel Health.   Counsel Health is an AI-native virtual care platform combining medical AI with human doctors to provide accessible, high-quality guidance at a fraction of traditional costs.   In this episode, we discuss building the new front door to care.   We also cover:   AI-native primary care via messaging AI vs. human roles in clinical decisions Redefining cost and access for personalized medicine   Subscribe to the podcast → insider.fitt.co/podcast  Subscribe to our newsletter → insider.fitt.co/subscribe  Follow us on LinkedIn → linkedin.com/company/fittinsider    Counsel Health's Website: https://www.counselhealth.com/    -   The Fitt Insider Podcast is brought to you by EGYM. Visit EGYM.com to learn more about its smart fitness ecosystem for fitness and health facilities.   Fitt Talent: https://talent.fitt.co/  Consulting: https://consulting.fitt.co/  Investments: https://capital.fitt.co/    Chapters: (00:00) Introduction (01:09) Muthu's background (01:40) What is Counsel Health (03:08) Patient interaction and care modules (04:27) From AI to human doctors (05:38) The clinician side (06:45) The clinician cockpit (07:47) The AI healthcare landscape (09:16) Medical information vs. medical care (10:38) Re-aggregating fragmented primary care (12:00) The 10x doctor (13:45) AI autonomy (15:00) Will AI replace doctors entirely? (16:45) Cognitive aspects of primary care  (18:59) Recent AI healthcare product releases (20:30) Integration challenges (22:00) Clinical use cases  (23:15) Patient adherence challenges (25:45) Series A fundraising  (27:15) Scarcity and value in the AI healthcare era (28:15) Business model challenges (30:15) Improving quality, lowering cost, and improving access (31:00) Prevention vs. primary care (33:00) Wearables and lab data (34:00) Full-stack convergence vs. singular focus (35:45) What's next (36:58) Conclusion  

Struggling with hunger during your cut? Try Calocurb for natural appetite support that activates GLP-1 to help you feel satisfied. Clinical studies showed a 40% reduction in cravings and 30% reduction in hunger within one hour. Get 10% off at witsandweights.com/calocurb--Hungry after every workout and stuck in an endless “eat less, move more” loop? Strength training is actually one of the most powerful appetite control tools you have, but most people only think of it as a muscle-building tool.Learn the science behind why lifting suppresses hunger hormones like ghrelin while boosting satiety signals like GLP-1 and PYY. We cover why cardio often backfires through energy compensation, leaving you hungrier and more fatigued without the fat loss results. And discover the behavioral shifts that make strength training superior for long-term body recomposition.Plus, get a template for building an appetite-friendly training week, cardio structured to avoid spiking your hunger, and a specific post-workout timing strategy to eliminate overeating at your hardest meal of the day.Timestamps0:00 – Strength training for appetite control 3:38 – How cardio triggers energy compensation and stalls fat loss 7:42 – The gut hormone shifts that suppress hunger after lifting 12:31 – How protein cravings and reward substitution change your eating 16:27 – Building a training week that supports fat loss and controls appetite 20:12 – How to adjust cardio to lose fat without spiking hunger 23:47 – 3 myths keeping you stuck (cardio, calories, and willpower) 27:12 – Bonus: post-workout timing trick to stop overeating at dinnerSupport the show

How can we use our imagination to transform individually and our collective consciousness? Clinical psychologist Dr. Diana Hill explores this question with Dr. Cassandra Vieten on The Wise Effort Show. Dr. Vieten, a clinical professor and director of research at multiple institutions, shares her extensive research on the subject, emphasizing the profound impact transformative spiritual experiences can have on changing our worldview and behaviors. Listeners will learn about the conditions that support transformation, the importance of imagination in altering future outcomes, and practical approaches to fostering a shift in consciousness. Vieten's compelling personal anecdotes and scientific insights provide a roadmap for understanding and achieving deep, lasting change.Listen and learn:Scientific Approach to TransformationThe Power of Imagination in TransformationImagination and Worldview TransformationImagination in Practice and TherapyImagining a Better FutureRelated ResourcesGet enhanced show notes for this episodeOrder my book, Wise Effort: How to Focus Your Genius Energy on What Matters Most, and receive special bonus gifts.Want to become more psychologically flexible? Take Diana's "Foundations of ACT" course.Diana's EventsReserve your spot in Diana's Costa Rica retreat in 2026!See Diana at an upcoming eventConnecting With DianaSubscribe for free on Apple Podcasts and Spotify.Leave a 5-star review on Apple so people like you can find the show.Sign up for the free Wise Effort Newsletter.Become a Wise Effort member to support the show.Follow Diana on YouTube, Instagram, LinkedIn, Facebook, and

In this in-depth episode of Breaking the Rules, we unpack two commonly confused but fundamentally different clinical presentations: moral scrupulosity (OCD) and Obsessive Compulsive Personality Disorder (OCPD). While they may look similar on the surface—perfectionism, rigid values, intense guilt—the treatment implications couldn't be more different.The conversation explores how moral scrupulosity shows up across children, teens, and adults, often hiding beneath “good behaviour,” people-pleasing, over-apologising, and chronic self-monitoring. We also dive into why some clients become stuck in ERP when the underlying issue isn't OCD at all, but rigidity, control, and ego-syntonic perfectionism associated with OCPD.This episode is especially valuable for clinicians navigating stuckness, treatment resistance, or confusing presentations—and for anyone who has ever felt trapped by the need to be a “good person.”

Cardiologist Bob Harrington talks to Mitch Elkind, chief science officer for Brain Health and Stroke at the AHA, about the heart-brain connection and why what's good for the brain is good for the heart. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harrington Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association  https://www.ahajournals.org/doi/10.1161/CIR.0000000000001078 Migraine Headache: An Under-Appreciated Risk Factor for Cardiovascular Disease in Women https://www.ahajournals.org/doi/10.1161/JAHA.119.014546 Cardiovascular disease patients have increased risk for comorbidity: A cross-sectional study in the Netherlands https://doi.org/10.1080/13814788.2017.1398318 Characteristics and treatment of midlife-onset epilepsy: A 24-year single-center, retrospective study https://doi.org/10.1002/epd2.20253 Traumatic Brain Injury and Risk of Neurodegenerative Disorder https://doi.org/10.1016/j.biopsych.2021.05.025 Cardiac Changes in Parkinson's Disease: Lessons from Clinical and Experimental Evidence https://doi.org/10.3390/ijms222413488 The neuropathological diagnosis of Alzheimer's disease https://doi.org/10.1186/s13024-019-0333-5 Failed Semaglutide for Early Alzheimer's Not the End of the Road? https://www.medscape.com/viewarticle/failed-semaglutide-early-alzheimers-not-end-road-2025a1000y4l Atrial Fibrillation and Dementia: A Report From the AF-SCREEN International Collaboration https://doi.org/10.1161/circulationaha.121.055018 Reduced regional cerebral blood flow in patients with heart failure https://doi.org/10.1002/ejhf.874 Heart-brain Interactions in Heart Failure https://doi.org/10.15420/cfr.2018.14.2 While You Were Sleeping, the Brain's 'Waste Disposal System' Was at Work https://www.medscape.com/viewarticle/while-you-were-sleeping-brains-waste-disposal-system-was-2025a1000mbb Repurposing Semaglutide and Liraglutide for Alcohol Use Disorder https://doi.org/10.1001/jamapsychiatry.2024.3599 2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines https://www.ahajournals.org/doi/10.1161/CIR.0000000000001356 "VOODOO" Death https://ajph.aphapublications.org/doi/full/10.2105/AJPH.92.10.1593 Longitudinal brain ageing after stroke: a marker for neurodegeneration and its relevance for upper limb motor outcome https://doi.org/10.1093/braincomms/fcaf299 Unlocking Longevity: Aging Reimagined  https://www.medscape.com/viewarticle/1002241 You may also like: Hear John Mandrola, MD's summary and perspective on the top cardiology news each week, on This Week in Cardiology https://www.medscape.com/twic Questions or feedback, please contact news@medscape.net

What if the most overlooked organ in menopause is your skin?In this episode, Bahar speaks with Dr David Kosenko, Head of Medical and Clinical Training at Dermacosmetica, President of the Cosmetic Physicians College of Australasia, and a practising cosmetic physician with more than 30 years of clinical experience. They unpack the biological impact of oestrogen loss on the skin, why collagen declines rapidly after menopause, and how to support hormonal skin health with evidence-based care. Dr Kosenko explains MEP technology in Emepelle, a non-hormonal innovation that activates oestrogen receptors in the skin without systemic effects. The conversation also explores regenerative aesthetics, skincare routines for perimenopause and postmenopause, and the future of hormonal skin science. This episode is in partnership with Emepelle for Menopause Awareness Month.Topics covered in this episode include Menopause and skin health Oestrogen receptor function in skin Collagen loss in the first five years after menopause Adapting skincare for perimenopause and postmenopause Non-hormonal MEP technology and the innovation behind Emepelle explained Clinical results from the 20-week study How MEP in Emepelle differs from topical HRT creams Recommended skincare essentials (cleansers, antioxidants, SPF, retinoids) Regenerative aesthetics and collagen stimulation Visible improvements on neck and hands Why it is never too late to rejuvenate skin Chapters 00:00:00 Introduction to Menopause and Skin00:03:00 The Role of Estrogen in Skin Health00:09:00 Innovative Skincare Solutions00:15:00 Understanding MEP Technology00:21:00 Empowering Women Through Skincare Watch the full episode here: https://youtu.be/v1sAABo2xGESee omnystudio.com/listener for privacy information.

Clinical skills can take years to sharpen. But without trust, connection, and communication, you might never get the chance to use them.In this episode, Matt Glassoff throws a curveball at traditional PT training with a powerful take: if you can't connect with people, your skills don't matter. He breaks down what real patient rapport looks like, how to lead with empathy, and why this message is more important now than ever.???? Topics Covered:Why patients care more about you than your techniquesHow to build trust quickly and authenticallyMistakes Matt made early on — and what he learnedActionable ways to develop human connection in healthcare

Are you wondering why your clinically sound medical device still isn't being adopted—even after pilots, approvals, and glowing data?If you're a clinician founder ready to take your MedTech prototype to market, this episode breaks down the overlooked reason most devices fail to gain traction. It's not the product—it's your go-to-market execution. Learn how behavior change, system fit, and implementation science play a bigger role than your evidence ever will.Discover the #1 mistake clinical founders make after running pilotsLearn how to identify all the “whos” involved in adoption—and why missing one can ruin your rolloutUnderstand how to turn barriers into behavior-changing strategies that scale across bordersPress play to learn the proven system for moving your MedTech device from “great pilot” to international success—without wasting cash or time.Message me via DM on LinkedinBook a 30 min discovery call for the Healthcare Export Accelerator ProgrammeThis podcast is for clinicians turning medical devices into real businesses, with practical insight on go to market strategy, exporting, and scaling in international MedTech.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss screwworm, how the shingles vaccination slows biological aging (for all of you who want to reset 'the clock' and live forever…..you know who you are Musk, Bezos) and getting one dose of the HPV vaccine, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, how losing our elimination status is the cost of doing business (going for broke is never a good business model !) where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, the effectiveness of this season's influenza vaccine, where to go for answers to your long COVID questions and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode New World Screwworm: Outbreak Moves into Northern Mexico……with an official tag "This is an official CDC Health Advisory" (CDC: Health Alert Network) Association between shingles vaccination andslower biological aging: Evidence from a U.S. population-based cohort study (The Journals of Gerontology series A) Noninferiority of One HPV Vaccine Dose to Two Doses (NEJM) Herd effect of human papillomavirus vaccination on incidence of high-grade cervical lesions: (LANCET: Public Health) Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service) Detections of Highly Pathogenic Avian Influenza in Wild Birds (USDA: Animal and Plant Health Inspection Service) Delaware, Georgia see major commercial avian flu outbreaks (CIDRAP) Wastewater for measles (WasterWater Scan) Notes from the Field: Wastewater Surveillance for Measles Virus During a Measles Outbreak — Colorado, August 2025 (CDC: MMWR) Notes from the Field: Retrospective Analysis of Wild-Type Measles Virus in Wastewater During a Measles Outbreak — Oregon, March 24–September 22, 2024 (CDC: MMWR) Measles cases and outbreaks (CDC Rubeola) Measles vaccine recommendations from NYP (jpg) Tracking Measles Cases in the U.S. (Johns Hopkins) Utah measles total rises to 216; CDC deputy director says losing elimination status'cost of doing business' (CIDRAP) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Assessing MMR vaccination coverage gaps in US children with digital participatory surveillance (Nature Health) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) Effectiveness of influenza vaccination to prevent severe disease: a systematic review and meta-analysis of test-negative design studies (CMI: Clinical Microbiology and Infection) Interim vaccine effectiveness against influenza virus among outpatients, France, October 2025 to January 2026 (Eurosurveillance) Moderate protection from vaccination against influenza A(H3N2) subclade K in Beijing, China, September to December 2025 (Eurosurviellance) Current flu vaccine provides moderate protection against severe disease, interim analyses suggest (CIDRAP) OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virusnfection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) UnderstandingCoverageOptions (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1290 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

Reference: Aronson PL, et al. Prediction Rule to Identify Febrile Infants 61–90 Days at Low Risk for Invasive Bacterial Infections. Pediatrics. September 2025 Date: January 6, 2026 Guest Skeptic: Dr. Jillian Nickerson is a pediatric emergency medicine attending at Children's National Hospital and Assistant Professor of Pediatrics and Emergency Medicine at The George Washington University […] The post SGEM#501: Here it Goes Again – Another Clinical Decision Rule for Febrile Infants 61-90 Days first appeared on The Skeptics Guide to Emergency Medicine.

Performance technology is everywhere right now.Force plates. Dynamometry. Movement analysis. Dashboards full of numbers that look impressive and explain nothing. In Part 1 of this two-part series, Dr. Michael “Dr. G” Giammarco breaks down how performance technology should actually be used in clinical and performance settings. Not as a diagnosis machine, but as a decision-support tool that adds context, clarity, and confidence to your reasoning.This conversation focuses on cutting through the noise. Instead of chasing more data, Dr. G explains how to select the right metrics, interpret them intelligently, and integrate technology into real-world workflows without slowing sessions, overwhelming staff, or confusing patients.If you have ever felt stuck between ignoring tech completely or drowning in dashboards you do not fully trust, this episode provides a clear reset. This episode is especially valuable for: Healthcare providers, rehab professionals, strength coaches, athletic trainers, and clinic owners who want technology to support their thinking, not replace it.In This Episode, You'll Learn:What performance technology actually includes and what it does notWhy collecting more metrics often leads to less clarityHow dashboards create analysis paralysis without a guiding frameworkHow to choose metrics that match the person in front of youThe real-world realities of implementation, including needs analysis, staff training, workflow bottlenecks, and ROIWhy technology should add context rather than override clinical reasoningThis is Part 1 of a two-part series. Tune in for Part 2 (Episode 121) in two weeks.

Jonathan Pearce joins John Murray & Ian Dennis to talk football, travel & language. John is back from Bodø, Jonathan tells tales of changing football on the radio, his thoughts on the Cantona kung-fu kick commentary & Robot Wars reflections. Plus which commentary phrase will JP add to our Great Glossary? Suggestions welcome on WhatsApp voicenotes to 08000 289 369 & emails to TCV@bbc.co.uk00:25 John back from Bodø, 04:00 5 Live commentaries this weekend, 10:55 Does Jonathan like the new Champions League format? 13:15 How Jonathan changed football on the radio, 24:35 Jonathan's best gaffes, 32:25 Cantona's kung-fu kick, 39:05 Robot Wars reflections, 44:40 Great Glossary of Football Commentary, 54:05 Bonus Bobby Moore story.5 Live / BBC Sounds commentaries: Sat 1500 Burnley v Tottenham, Sat 1500 Man City v Wolves, Sat 1730 Bournemouth v Liverpool. Sun 1400 Newcastle v Aston Villa, Sun 1400 Crystal Palace v Chelsea on Sports Extra, Sun 1400 Brentford v Nott'm Forest on Sports Extra 2, Sun 1630 Arsenal v Man Utd, Wed 2000 PSG v Newcastle, Wed 2000 Man City v Galatasaray on Sports Extra, Wed 2000 Napoli v Chelsea on Sports Extra 2.Great Glossary of Football Commentary: DIVISION ONE Back to square one, Bosman, Cruyff Turn, Cultured/educated left foot, Dead-ball specialist, Draught excluder, Elastico/flip-flap Fox in the box, Giving the goalkeeper the eyes, Grub hunter, Head tennis, Hibs it, In a good moment, In behind, Magic of the FA Cup, The Maradona, Off their line, Olimpico, Onion bag, Panenka, Park the bus, Perfect hat-trick, Rabona, Roy of the Rovers stuff, Schmeichel-style, Scorpion kick, Spursy, Tiki-taka, Trivela, Where the kookaburra sleeps, Where the owl sleeps, Where the spiders sleep. DIVISION TWO Back on the grass, Ball stays hit, Beaten all ends up, Blaze over the bar, Business end, Came down with snow on it, Catching practice, Camped in the opposition half, Cauldron atmosphere Coat is on a shoogly peg, Come back to haunt them, Corridor of uncertainty, Couldn't sort their feet out, Easy tap-in, Daisy-cutter, First cab off the rank, Giant-killing, Good leave, Half-turn, Has that in his locker, High wide and not very handsome, Hospital pass, Howler, In the dugout, In their pocket, Johnny on the spot, Leading the line, Nice headache to have, Nutmeg, On their bike, One for the cameras, One for the purists, Played us off the park, Points to the spot, Prawn sandwich brigade, Purple patch, Put their laces through it, Reaches for their pocket, Rolls Royce, Root and branch review, Row Z, Screamer, Seats on the plane, Show across the bows, Slide-rule pass, Steal a march, Straight in the bread basket, Stramash, Taking one for the team, Telegraphed that pass, Tired legs, That's great… (football), Thunderous strike, Turns on a sixpence, Walk it in, We've got a cup tie on our hands. UNSORTED 2-0 is a dangerous score, After you Claude, All-Premier League affair, Aplomb, Bag/box of tricks, Brace, Brandished, Bread and butter, Breaking the deadlock, Bundled over the line, Champions elect / champions apparent, Clinical finish, Commentator's curse, Coupon buster, Denied by the woodwork, Draught excluder, Elimination line, Fellow countryman, Foot race, Formerly of this parish, Free hit, Goalkeepers' Union, Goalmouth scramble, Good touch for a big man, Honeymoon Period, In and around, In the shop window, Keeping ball under their spell, Keystone Cops defending, Languishing, Loitering with intent, Marching orders, Nestle in the bottom corner, Numbered derbies, Opposite number, PK for penalty-kick, Postage stamp, Put it in the mixer, Rasping shot, Red wine not white wine, Relegation six-pointer, Rooted at the bottom, Route One, Sending the goalkeeper the wrong way, Shooting boots, Sleeping giants, Slide rule pass, Small matter of, Spiders web, Stayed hit, Steepling, Stinging the palms, Stonewall penalty, Straight off the training ground, Taking one for the team, Team that likes to play football, Throw their cap on it, Thruppenny bit head / 50p head, Towering header, Two good feet, Turning into a basketball match, Turning into a cricket score, Usher/Shepherd the ball out of play, Walking a disciplinary tightrope, Wand of a left foot, Wrap foot around it, Your De Bruynes, your Gundogans etc.

Therapy isn't confined to an office. Discover how remote sessions are creating deeper breakthroughs and transforming mental health recovery from the comfort of home. Clinical psychologist Lexi Palomo reveals the nuanced frameworks and the power of existential, client-led therapy that are changing lives through a screen. Dive into a conversation that bridges psychology and the legal system, and learn how true curiosity unlocks lasting healing. This is more than a session; it's a new pathway to understanding the mind.

Attention Dental Hygiene Students - This episode breaks down the neuroanatomy of pain control in a way that helps dental hygiene students understand why local anesthesia works, how nerves transmit pain, and what clinicians must consider when applying this knowledge chairside. We connect foundational neuroscience to everyday clinical decision‑making so students can move from memorization to confident practice.In this episode, I want to help you build the confidence you need to rely on your foundational knowledge of neuroanatomy. Additional resources: Leave me a message or send a question I can share on the Podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Time Management Prioritization Quiz - Find out how you rate ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠HERE ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Study Sheets: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://thehappyflosserrdh.etsy.com/ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Specialized Course: How to be successful in Dental Hygiene School⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://billie-lunt-s-school.teachable.com/p/how-to-be-successful-in-dental-hygiene-school⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Other Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠blog.feedspot.com/dental_hygiene_podcasts/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  Email Me: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠HappyflosserRDH@gmail.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Leave me a message or ask a question I can share on the Podcast ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Here ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Check out my free scorecard for students - you can rank yourself on how you are doing to take action on the steps toward being a successful college student. Study Sheets: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://thehappyflosserrdh.etsy.com/ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Specialized Course: How to be successful in Dental Hygiene School⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://billie-lunt-s-school.teachable.com/p/how-to-be-successful-in-dental-hygiene-school⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

This Physician World Shared Practice Forum Podcast explores two multicenter studies on extubation outcomes in neonates and children following congenital cardiac surgery. These studies incorporate integration of machine learning and risk analytics for extubation decision-making, and examine extubation readiness and extubation failure outcomes. LEARNING OBJECTIVES - Understand the key factors influencing extubation outcomes following congenital cardiac surgery - Examine the use of machine learning and risk analytics in neonatal and pediatric extubation decisions - Discuss how machine learning can improve clinical decision-making and patient safety AUTHORS Daniel Hames, MD, MPH Assistant Professor of Pediatrics, Cardiac Care Unit Director of Quality and Safety University of Nebraska Medical Center Children's Nebraska Jeffrey Burns, MD, MPH Emeritus Chief Division of Critical Care Medicine Department of Anesthesiology, Critical Care and Pain Medicine Boston Children's Hospital Professor of Anesthesia Harvard Medical School DATE Initial publication date: January 27, 2026. ARTICLES REFERENCED - Hames DL, Abbas Q, Asfari A, Borasino S, Diddle JW, Gazit AZ, Lipsitz S, Marshall A, Reise K, Guerineau LR, Wolovits JS, Salvin JW. Extubation Failure in Neonates Following Congenital Cardiac Surgery: Multicenter Retrospective Cohort, 2017-2020. Pediatr Crit Care Med. 2025 May 1;26(5):e590-e599. doi: 10.1097/PCC.0000000000003703. Epub 2025 Feb 10. PMID: 39927824. - Hames DL, Abbas Q, Asfari A, et al. Clinical and Risk Analytics Associations With Extubation Failure in Children Following Congenital Cardiac Surgery: A Multicenter Retrospective Cohort Study, 2017-2020. Pediatr Crit Care Med. 2025;26(9):e1105-e1114. doi:10.1097/PCC.0000000000003793. TRANSCRIPT https://cdn.bfldr.com/D6LGWP8S/as/w7qqc97g6m9g5n5vrq5vkx6x/202601_WSP_Hames_Transcript. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu CITATION Hames DL, Burns JP. Integrating Risk Analytics in Post-Cardiac Surgery Extubation Readiness. 01/2026. OPENPediatrics. Online Podcast.

Lichun marks the release of winter's stagnation and the first stirring of spring Yang. Drawing from classical texts and clinical experience, Yvonne Lau explores how seasonal transition influences Liver Qi and emotional regulation. You can access the written article here: https://www.mayway.com/blogs/articles/lichun-beginning-of-spring-clinical-reflections-on-seasonal-transitionSee our Monthly Practitioner Discounts https://www.mayway.com/monthly-specialsSign up for the Mayway Newsletterhttps://www.mayway.com/newsletter-signupFollow ushttps://www.facebook.com/MaywayHerbs/https://www.instagram.com/maywayherbs/

Dr. Chris Goss (Medicine, Pediatrics; Associate Dean for Clinical Research) discusses ways faculty can partner with industry to fund clinical research, serving their patients with cutting-edge science. Dr. Goss recommends working with your department and the UW Clinical Trials Office who can help with the entire study process including conversations with industry partners, IRB questions, and site-specific resources. He walks through the timeline and responsibilities involved with being a principal investigator in a clinical trial and provides tips for how to be successful amidst common bottlenecks and challenges. Clinical research at UW has grown significantly and may be an excellent pathway for faculty looking to diversify their research funding.Learn about the UW Clinical Trials Office here.Music by Kevin MacLeod (https://incompetech.com/)

Two-time Emmy and Three-time NAACP Image Award-winning, television Executive Producer Rushion McDonald interviewed Shelby Williams.

Two-time Emmy and Three-time NAACP Image Award-winning, television Executive Producer Rushion McDonald interviewed Shelby Williams.

Two-time Emmy and Three-time NAACP Image Award-winning, television Executive Producer Rushion McDonald interviewed Shelby Williams.

Patrick McKenzie (patio11) is joined by Ruxandra Teslo to discuss why drug development keeps getting more expensive despite revolutionary new treatment modalities from GLP-1 agonists to gene therapies. They discuss Eroom's Law (Moore's Law in reverse) and Ruxandra's Common Technical Document Project, which aims to build the "Stack Overflow of clinical development" by making regulatory submissions publicly accessible. This will fill a present hole in the education of researchers, lower barriers for small biotechs, and accelerate drug discovery.–Full transcript available here: https://www.complexsystemspodcast.com/ruxandra-teslo/ –Sponsor: FramerBuilding and maintaining marketing websites shouldn't slow down your engineers. Framer gives design and marketing teams an all-in-one platform to ship landing pages, microsites, or full site redesigns instantly—without engineering bottlenecks. Get 30% off Framer Pro at framer.com/complexsystems.–Links:Eroom's Law (original paper): https://www.nature.com/articles/nrd3681Ruxandra's writing: https://www.writingruxandrabio.com/ Ross Rheingans-Yoo on drug development: https://open.spotify.com/episode/4GiO0KYqxJNCIdltCyhN6m?si=2znQniZ3RXKuX8keNcwWtw Ben Reinhardt on science and development: https://open.spotify.com/episode/0GHegWgLSubYxvATmbWhQu?si=pVCJVITYTqaq65BiST2d0Q–Timestamps:(00:00) Intro(00:56) Challenges in biopharma productivity(03:12) Understanding clinical development(04:59) The role of basic science in drug development(07:39) Clinical development process explained(09:25) Issues in clinical trials and development(19:33) The role of information in clinical trials(20:30) Sponsor: Framer(21:42) The role of information in clinical trials (continued)(32:55) Proposed solutions for clinical development(40:31) Consultant opinions and regulatory documents(41:28) Streamlining the regulatory process(43:06) Understanding FDA interactions(45:35) Building a public library of regulatory documents(48:18) Encouraging novel approaches in biotech(50:06) Addressing risk aversion in the industry(51:52) Analyzing FDA consistency and reviewer heterogeneity(01:02:15) The importance of courage in professional growth(01:06:39) Supporting young professionals and catalyzing change(01:16:14) Wrap

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., president and CEO of Mayo Clinic Laboratories, to discuss 2026 trends. Together, they explore:  JP Morgan Healthcare Conference (00:34): Dr. Morice shares his top observations and takeaways after attending this year's conference. Artificial intelligence (06:02): Anticipated benefits and risks of AI developments predicted in 2026.Reimbursement and regulation (13:43): Why reimbursement and regulation continue to be areas of significant interest in clinical diagnostics. Note: Information in this post was accurate at the time of its posting.ResourcesTransforming laboratory medicine through AI: From promise to practice"Answers From the Lab" podcast: Breakthroughs and Trends That Defined Lab Medicine in 2025"Answers From the Lab" podcast: PAMA Update and Accelerating Research and Development With BioPharma Diagnostics

Saffron supports both mood and sexual function, addressing a common problem where depression treatments often blunt intimacy Clinical trials show a daily 30-milligram dose of saffron reduces depression symptoms at a level similar to common antidepressants used for mild to moderate depression Unlike many psychiatric drugs, saffron improves erectile function, arousal, lubrication, and sexual satisfaction instead of worsening them Saffron works best when underlying stressors such as inflammation, poor cellular energy production, and gut imbalance are addressed at the same time Consistent daily use for six to eight weeks, combined with stable sleep, movement, sunlight, and a low-seed oil diet, produces the most reliable results

Most herbalists begin with books, teachers, and tradition, but genuine clinical mastery comes from organizing what you know into something you can actually use. In this episode, we will look at why the clinical herbal monograph is the most powerful tool for studying medicinal plants and how to build one that supports real-world practice rather than just theory.   Here's what you'll learn: What defines a clinical herbal monograph The essential elements every useful monograph should include How to think in terms of patterns, rather than "good for" lists Which information is helpful — and what only creates clutter Why writing your own monographs helps you to learn herbs deeply Join The Herbal Monograph Map FREE Workshop Series: https://www.evolutionaryherbalism.com/the-herbal-monograph-map/?utm_medium=social&utm_source=instagram.com&utm_campaign=mmm+optin ———————————— CONNECT WITH SAJAH AND WHITNEY ———————————— To get free in depth mini-courses and videos, visit our blog at:  http://www.evolutionaryherbalism.com   Get daily inspiration and plant wisdom on our Facebook and Instagram channels: http://www.facebook.com/EvolutionaryHerbalism https://www.instagram.com/evolutionary_herbalism/   Be sure to subscribe to our YouTube Channel: https://www.youtube.com/channel/UCyP63opAmcpIAQg1M9ShNSQ   Get a free 5-week course when you buy a copy of the book, Evolutionary Herbalism: https://www.evolutionaryherbalism.com/evolutionary-herbalism-book/   Shop our herbal products:  https://naturasophiaspagyrics.com/   ———————————— ABOUT THE PLANT PATH ———————————— The Plant Path is a window into the world of herbal medicine. With perspectives gleaned from traditional Western herbalism, Ayurveda, Chinese Medicine, Alchemy, Medical Astrology, and traditional cultures from around the world, The Plant Path provides unique insights, skills and strategies for the practice of true holistic herbalism. From clinical to spiritual perspectives, we don't just focus on what herbs are "good for," but rather who they are as intelligent beings, and how we can work with them to heal us physically and consciously evolve.   ———————————— ABOUT SAJAH ———————————— Sajah Popham is the author of Evolutionary Herbalism and the founder of the School of Evolutionary Herbalism, where he trains herbalists in a holistic system of plant medicine that encompasses clinical Western herbalism, medical astrology, Ayurveda, and spagyric alchemy. His mission is to develop a comprehensive approach that balances the science and spirituality of plant medicine, focusing on using plants to heal and rejuvenate the body, clarify the mind, open the heart, and support the development of the soul. This is only achieved through understanding and working with the chemical, energetic, and spiritual properties of the plants. His teachings embody a heartfelt respect, honor and reverence for the vast intelligence of plants in a way that empowers us to look deeper into the nature of our medicines and ourselves. He lives on a homestead in the foothills of Mt. Baker Washington with his wife Whitney where he teaches, consults clients, and prepares spagyric herbal medicines.    ———————————— WANT TO FEATURE US ON YOUR PODCAST? ———————————— If you'd like to interview Sajah or Whitney to be on your podcast, click here to fill out an interview request form.

Did you know that nearly 50% of women experience hair changes during menopause? In this expert-led conversation, we uncover the truth behind menopausal hair thinning, shedding, and texture changes with Dr. Isabelle Raymond, SVP of Clinical and Medical Affairs at Nutrafol. Dr. Raymond is dedicated to advancing women's health, with a particular focus on the biological and lifestyle factors that impact hair health during midlife. We explore the six root causes of hair thinning, the critical role of nutrition and hormones in hair growth, and why clinically backed research is essential for proven hair wellness solutions. Show Notes/Links: www.hotflashescooltopics.com Nutrafol: Link WE GREATLY APPRECIATE 5 STARS AND REVIEWS! Find Us Here! Website I [http://hotflashescooltopics.com/] Mail I [hotflashescooltopics@gmail.com] Instagram I [https://www.instagram.com/hotflashesandcooltopics/] Facebook : [www.facebook.com/hotflashescooltopics] YouTube I [https://www.youtube.com/@HotFlashesCoolTopics] Pinterest I [https://www.pinterest.com/hcooltopics/]

At some point in your career as a therapist, the work begins to shift. You may feel a quiet pull to share what you've learned beyond the therapy room but feel unsure what that means or whether you're "qualified" to teach. In this episode, I explore the transition from clinician to educator and why this identity shift can feel both exciting and uncomfortable. I talk about common myths therapists hold about teaching, ethical considerations, visibility, and how stepping into an educator role doesn't require a new certification or a major career change. If you're a mid-career or seasoned clinician curious about teaching, mentoring, or continuing education, this episode is an invitation to notice the pull and explore it with clarity and confidence. Links mentioned:

In this episode of Skin Anarchy, Dr. Ekta Yadav welcomes Carolina Reis Oliveira and Alessandra Zonari, co-founders of OneSkin, for a rigorous, eye-opening conversation that reframes skincare as a true longevity intervention. Part of the Lessons in Longevity series, this episode asks a bold question: what if skin aging isn't cosmetic at all—but cellular, systemic, and deeply biological?OneSkin began not as a brand, but as a lab-based mission. Trained in stem cell biology, tissue engineering, and genomics, Carolina and Alessandra spent years growing real human skin in the lab to test existing products. What they found challenged the industry: many so-called “anti-aging” formulas increased inflammation, cellular stress, and long-term damage. Meanwhile, longevity science was accelerating—yet skin, the body's largest organ, was being left out of the conversation.At the center of the episode is cellular senescence—a state where damaged cells stop dividing and begin secreting inflammatory signals that degrade surrounding tissue. In skin, this process weakens the barrier, disrupts collagen, and accelerates visible aging. Rather than masking symptoms, OneSkin set out to target this root cause. After screening hundreds of compounds, they developed OS-01, a proprietary peptide shown in lab models to significantly reduce senescent cell burden while increasing collagen—without irritation.The conversation also expands beyond the face. OneSkin's decision to focus on body skin revealed something unexpected: improving the skin barrier may reduce systemic inflammation. Clinical data discussed in the episode suggests that healthier skin doesn't just look better—it may influence whole-body aging.This episode is a must-listen for anyone curious about where skincare, biotech, and longevity science truly intersect.Listen to the full episode of Skin Anarchy to hear how OneSkin is redefining skin as a living organ—and why the future of longevity may start at the surface.SHOP ONESKINDon't forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform.Reach out to us through email with any questions.Sign up for our newsletter!Shop all our episodes and products mentioned through our ShopMy Shelf!Support the show