Podcasts about Clinical

Mesh infections are dreaded complications in hernia repair. This episode highlights relevant mesh properties, pathogens, and management strategies so you can tackle the next mesh infection with confidence! Hosts: Dr. Maggie Bosley - @MBosleyMD Dr. Sean Orenstein - @OrensteinSean Dr. Amber Sandoval Dr. Peter Ferrin Institution: Oregon Health & Science University Learning Objectives - Compare the long-term weight loss and diabetes remission rates of Gastric Bypass vs. Sleeve Gastrectomy. - Identify the appropriate revision options (Bypass vs. Sadie) for a patient with a failed sleeve based on the reason for failure (reflux vs. weight regain). - Recognize that all bariatric operations are superior to untreated obesity, making patient selection paramount. Episode Sponsor Disclosures: Visit goremedical.com/btk to learn more about GORE® ENFORM Biomaterial. Refer to Instructions for Use at eifu.goremedical.com for a complete description of all applicable indications, warnings, precautions and contraindications for the markets where this product is available. Rx only Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.   If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listen Behind the Knife Premium: General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-review Trauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlas Dominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkship Dominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotation Vascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-review Colorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-review Surgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-review Cardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-review Download our App: Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049 Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

Clinical psychologist and author Dr. Diana Hill joins Gabby to explore how to channel your energy with intention and align your strengths for greater clarity and purpose. While discussing her new book Wise Effort, she explains to Gabby and the audience that each of us has a “genius” that we haven't yet tapped into. Drawing on mindfulness and behavioral science, Diana shares how to move from striving to wise effort by knowing when to push, when to pause, and how to focus your time on what truly matters. Together they discuss self compassion, discipline and how to cultivate balance while pursuing meaningful goals. Dr. Diana Hill Instagram https://www.instagram.com/drdianahill/ Dr. Diana Hill Facebook https://www.facebook.com/drdianahill/ Dr. Diana Hill Linkedin https://www.linkedin.com/in/drdianahill/  Dr. Diana Hill Website https://drdianahill.com/ Thank You to Our Sponsors Timeline - My friends at Timeline are offering 20% off, just for my listeners. Head to timeline.com/gabby to get started. Ritual - Get 25% off your first month at ritual.com/GABBY Get 10% off TUSHY with the code GABBY10 at https://hellotushy.com/GABBY10 For more on Gabby Instagram @GabbyReece: https://www.instagram.com/gabbyreece/ TikTok @GabbyReeceOfficial https://www.tiktok.com/@gabbyreeceofficial The Gabby Reece Show Podcast on YouTube: https://www.youtube.com/@GabbyReece  The Gabby Reece Show podcast is produced by Rainbow Creative (https://www.rainbowcreative.co/)  Chapters 00:00 Introduction and Today's Message 00:26 Guest Introduction: Diana Hill 00:48 Sponsor Message: Timeline Longevity Gummies 02:57 Diana Hill's New Book: Wise Effort 05:46 Diana's Personal Journey and Struggles 06:34 The Myth of Persephone and Personal Genius 08:05 Understanding and Managing Personal Traits 12:08 The Role of Supportive Relationships 14:08 Finding Balance and Self-Acceptance 34:47 Curiosity and Its Importance 37:44 Navigating Grief with Curiosity 39:06 The Rise of Openness in Psychology 40:42 The Tushy Bidet Experience 42:48 Understanding Wise Effort 50:51 Compassion vs. Empathy 58:32 Possibility vs. Probability 01:04:11 Final Thoughts and Reflections Learn more about your ad choices. Visit megaphone.fm/adchoices

Parenting a child who's struggling with mysterious symptoms can be frightening and exhausting. You bring them to the doctor, the tests come back “normal,” and yet you know something isn't right. You're not imagining it—it's real, and you're not alone.In this episode, Dr. Bill Rawls explains why Lyme disease testing often misses active infections, what it means for your child, and practical steps parents can take to advocate for accurate diagnosis and care.Why does my child keep testing negative for Lyme disease even when symptoms persist?False negatives are common: Many Lyme disease tests, like the ELISA (enzyme linked immunoassay) or Western blot, rely on antibodies that may not appear early or consistently.Early infection can be invisible: During the initial infection or early Lyme disease, the immune system may not have produced enough detectable antibodies for serologic testing.Co-infections complicate results: Other tick-borne illnesses can mask or mimic Lyme disease symptoms, making accurate diagnosis even harder.Persistent or chronic infections: Sometimes, persistent infection or chronic Lyme can continue even after a negative test. Clinical findings, medical history, and physical examination help guide your provider toward the right diagnosis of Lyme disease.It's not bad parenting—it's a dysregulated system of testing, not a failure of your vigilance.Even when bloodwork looks clear, your child may still have an active infection. Understanding test limitations helps reduce frustration and empowers you to take action.How can I tell if Lyme disease is being missed in my child?Watch for persistent, nonspecific symptoms: Fatigue, joint pain, headaches, or cognitive changes can appear long before tests turn positive.Consider medical history and exposure: Tick bites, outdoor activities, or living in endemic areas provide important clues.Use clinical judgment alongside lab tests: A single blood test rarely tells the full story; doctors often need multiple tests and examinations.You don't have to wait for a positive blood test to validate your child's suffering.Ready to help your child calm down quickly and regain control? Start using Quick Calm today and discover simple, science-backed strategies to regulate their nervous system.What are the limitations of standard Lyme disease testing?ELISA and Western blot tests measure antibodies, not bacteria directly: If your child's immune system hasn't produced detectable antibodies, the test can look clear.False positives and delayed diagnosis are common: Inaccurate results can delay treatment, allowing Lyme bacteria to persist and cause chronic symptoms.Tests vary in performance: Different labs, methods, and timing of testing affect results.Let's calm the brain first—then focus on gathering the right information without panic.Want to stay calm when your child pushes every button?Become a Dysregulation Insider VIP and get the FREE Regulation Rescue Kit—your step-by-step guide to stop oppositional behaviors without yelling or giving in.Go to www.drroseann.com/newsletter and grab your kit today.What should parents do if Lyme disease tests come back negative?Keep a detailed symptom log: Track fatigue, joint pain, rashes, and cognitive...

This episode explores how technology and healthcare intersect. We talk with Jhonatan Bringas Dimitriades, MD, CEO of Lapsi Health, about Keikku, the first FDA-cleared smart stethoscope with an AI scribe. You will hear how this tool impacts clinical workflows, patient communication, and the broader healthcare system.Key points covered • How clinicians use AI during real-world visits • Measurable time savings in documentation • Data privacy and HIPAA/GDPR compliance • Effects on clinician burnout and emotional fatigue • Future applications of AI in public health and care settings • Skills health professionals need as tech advancesWhy it matters • You see how AI tools shape medical decision-making and patient engagement • You get insight into how tech adoption fits into social systems and workplace culture • You hear practical examples that support ongoing conversations in public health and social scienceThink about this • How does technology influence trust in the patient-provider relationship? • What skills will workers need as AI expands in healthcare? • What policies should protect patients and providers as these tools grow?Listen and reflect on how innovation, behavior, culture, and care systems interact.Resources Mentioned:Website: https://www.keikku.health/Connect with Jhonatan: LinkedIn, Instagram, Twitter/XPhysician burnout researchStay Connected & Support the Show:Want to keep up with conversations like this that challenge the status quo and center community voices? Sign up for The Healthy Project newsletter at www.healthyproject.co for exclusive insights, resources, and updates you won't want to miss.Love what you're hearing? Support independent podcasting that prioritizes truth over trends. Join THP+ for just $5/month and get bonus content, early access to episodes, and the satisfaction of knowing you're fueling more conversations that matter.Visit www.healthyproject.co to subscribe and support today. ★ Support this podcast ★

Featuring a slide presentation and related discussion from Prof Patrick Neven, including the following topics: Biology of the estrogen receptor (ER) and mechanisms of resistance to therapy (0:00) Clinical trial data involving oral selective ER degraders (SERDs) for endocrine-resistant ER-positive, HER2-negative metastatic breast cancer (13:34) Utility of switching to an oral SERD before radiographic disease progression for patients receiving first-line endocrine treatment (23:12) Ongoing trials with oral SERDs for ER-positive, HER2-negative breast cancer (27:13) Case: Patient with ER-positive, HER2-negative breast cancer receives imlunestrant upon disease progression on first-line letrozole (32:34) Case: Patient with ER-positive, HER2-negative breast cancer receives imlunestrant/abemaciclib upon relapse on letrozole/abemaciclib (34:16) Case: Patient with ER-positive, HER2-negative breast cancer receives camizestrant after first-line tamoxifen (36:20) Case: Patient with ER-positive, HER2-negative breast cancer receives elacestrant after disease progression on first-line letrozole/palbociclib (38:11) CME information and select publications

TopMedTalk's Andy Cumpstey recorded this piece recently for us at the Royal College of Anaesthetists' Centre for Perioperative Care's (CPOC) annual meeting in London. The conversation features key figures from CPOC, including: David Selwyn, Acting Chief Executive at Sherwood Forest Hospitals NHS Foundation Trust, appointed as the inaugural Director of CPOC in May 2019, Denny Levitt, Professor in Perioperative Medicine and Critical Care at the University of Southampton and a Consultant in Perioperative Medicine at Southampton University Hospital NHS Foundation trust (UHS), Scarlett McNally, Consultant Orthopaedic Surgeon in Eastbourne DGH, UK since 2002, Deputy Director at the COPC (2020-26) and an honorary clinical professor at Brighton and Sussex Medical School, Jugdeep Dhesi, Deputy Director for CPOC, Clinical lead for the innovative and award winning POPS (Perioperative medicine for Older People undergoing Surgery) service, Honorary Reader at King's College London and Associate Professor at University College London, and Lawrence Mudford, who transitioned from a healthcare professional to a patient, following a cancer diagnosis. Following his successful treatment, he took up his current role as a patient representative for CPOC. The panel explore the creation and evolution of CPOC since its inception in 2019, highlighting the collaborative efforts to improve surgical pathways by integrating patient and multidisciplinary voices. They discuss various initiatives, guidelines, and successful practices aimed at enhancing patient-centered care, managing conditions like frailty, diabetes, and anaemia, and promoting shared decision-making. The episode also delves into future goals, such as addressing the implementation gap, fostering digital transformation, and operationalizing educational curricula for healthcare professionals to further support perioperative care.

In this episode, Dr Kat Ralston speaks to Dr Jane Rimer about a challenging clinical case which had an unexpected outcome. They discuss the importance of reflection with trusted colleagues and consider systems to help us cover the basics well. They explore how we can reduce the sense of isolation and vulnerability that is often encountered when we have to navigate complaints, adverse event reviews and legal processes, as illustrated by the title 'Defence against The Dark Arts'. Dr Jane Rimer is a Consultant Physician and Geriatrician in NHS Lothian. She is also Associate Postgraduate Dean for Medical Training in South East Scotland. Dr Kat Ralston is a geriatric medicine registrar in Edinburgh. She is also the Education Co-Vice Chair and the joint Podcast Lead for the RCPE Trainee & Members' Committee (T&MC). Recording Date: 29 July 2025 -- Follow us -- https://www.instagram.com/rcpedintrainees https://twitter.com/RCPEdinTrainees -- Upcoming RCPE events -- https://www.rcpe.ac.uk/events -- Become an RCPE Member -- https://www.rcpe.ac.uk/membership/join-college Feedback: cme@rcpe.ac.uk

Selhurst purring, Palace bossed Brentford from first whistle. Compact shape, crisp passing, and ruthless transitions earned a deserved 2-0. The press hemmed the Bees in, full-backs flew, and midfield snapped into everything. Clinical finishing, rock-solid defending, and game management. A comfortable, confident win that felt like lift-off in SE25. Superb.Support this show http://supporter.acast.com/holmesdaleradio. Hosted on Acast. See acast.com/privacy for more information.

In his weekly clinical update, Dr. Griffin and Vincent Racaniello ponder the nomination of Casey Means for Surgeon General by President Trump, how mRNA vaccines may enhance effectiveness of check point inhibitor cancer therapies, if viral infection associates with cardiac disease, H5N1 isolation from backyard birds and turkey farms, and the effectiveness of the COVID-19, RSV and influenza vaccines before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, if revaccination with the mRNA RSV vaccine is effective, how effective today's COVID-19 vaccine is for protection against severe disease following infection with current viral variants, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode The Challenge of Malignancies in HIV-1, Beyond Immune Activation and Back to Decreased Immune Surveillance (Journal of AIDS & Clinical Research) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1265: mRNA vaccines make cancer treatment great again (microbeTV: TWiV 1265) Viral Infections and Risk of Cardiovascular Disease (Journal of the American Heart Association) Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service) Three large turkey farms in Minnesota hit with H5N1 avian flu (CIDRAP) Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025–2026 (NEJM) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Measles vaccine recommendations from NYP (jpg) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: Cliff notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Safety, Tolerability, and Immunogenicity of Revaccination With mRNA-1345, an mRNA Vaccine Against RSV, Administered 12 Months Following a Primary Dose in Adults Aged ≥50 Years (CID) Vaccine effectiveness of a bivalent respiratory syncytial virus (RSV) pre-F vaccine against RSV-associated hospital admission among adults aged 75–79 years in England (LANCET: Infectious Diseases) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Association of 2024–2025 Covid-19 Vaccine with Covid-19 Outcomes in U.S. Veterans (NEJM) Durability of 2024-2025 COVID-19 Vaccines Against JN.1 Subvariants (JAMA: Internal Medicine) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Reaching out to US house representative Letters read on TWiV 1266 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

This episode discusses the evolving standards of care in providing support after rapid sequence intubation (RSI) and highlights RSI pharmacology and the management of post-intubation analgesia and sedation. CE for this episode expires on November 1, 2027.  The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.

Dr Sharonne Hayes, Professor of cardiovascular medicine and founding director of Mayo Clinic women's heart clinic, and Dr. Marysia Tweet, Associate Professor of cardiovascular medicine, and co-leader of the Spontaneous Coronary Artery Dissection Registry and leader in women's heart health join the show for this amazing November chapter of Always on EM. They are world experts on Spontaneous Coronary Artery Dissection authoring over 60 peer reviewed articles on the topic and in this chapter we explore with them the pitfalls and pearls related to making this diagnosis in the ED. SCAD is an important cause of myocardial infarction especially in patients who would not otherwise seem to be at risk for heart attacks for example active young women without comorbidities, and its imperitive that we as emergency physicians are current on this diagnosis.   DONATE TO DR JIM GREGOIRE SCHOLARSHIP FUND To honor the life of Dr. Jim Gregoire, dear friend of this show, consider donating to his scholarship fund. Go to https://give.mayoclinic.org/give/616870/#!/donation/checkout Go to: What would you like your donation to support? Choose “other” Enter: James Gregoire Scholarship Fund   CONTACTS X - @AlwaysOnEM; @VenkBellamkonda; @Marysia_Tweet; @SharonneHayes YouTube - @AlwaysOnEM; @VenkBellamkonda Instagram – @AlwaysOnEM; @Venk_like_vancomycin; @ASFinch; @SharonneHayes Email - AlwaysOnEM@gmail.com   DO YOU HAVE SCAD? DOES YOUR PATIENT HAVE SCAD? WANT TO GET CONNECTED? SCAD Research: www.scadresearch.org National Coalition for Women with Heart Disease: www.womenheart.org Mayo Clinic Womens Heart clinic: https://www.mayoclinic.org/departments-centers/womens-heart-clinic/overview/ovc-20442061   REFERENCES & LINKS Saleh G, Al-Abcha A, Chaaban K, Adi MZ, Tweet M, Collins JD, Alkhouli M, Gulati R. Concomitant Takotsubo Cardiomyopathy and Spontaneous Coronary Artery Dissection: Exploring the Role of Cardiac Mechanics on Coronary Disruption. JACC Cardiovasc Imaging. 2025 Oct;18(10):1161-1166. doi: 10.1016/j.jcmg.2025.05.020. Epub 2025 Aug 5. PMID: 40758075. Baqal O, Karikalan SA, Hasabo EA, Tareen H, Futela P, Qasba RK, Shafqat A, Qasba RK, Hayes SN, Tweet MS, El Masry HZ, Lee KS, Shen WK, Sorajja D. In- hospital and long-term outcomes in spontaneous coronary artery dissection with concurrent cardiac arrest: Systematic review and meta-analysis. Heart Rhythm O2. 2025 Apr 24;6(6):843-853. doi: 10.1016/j.hroo.2025.03.023. PMID: 40717849; PMCID: PMC12287955. Morosato M, Gaspardone C, Romagnolo D, Pagnesi M, Baldetti L, Dormio S, Federico F, Scandroglio AM, Chieffo A, Godino C, Margonato A, Adamo M, Metra M, Tchetche D, Dumonteil N, Tweet MS, Saw J, Beneduce A. Left Main Spontaneous Coronary Artery Dissection: Clinical Features, Management, and Outcomes. JACC Cardiovasc Interv. 2025 Apr 28;18(8):975-983. doi: 10.1016/j.jcin.2025.01.427. Epub 2025 Apr 9. PMID: 40208153; PMCID: PMC12290918. Tweet MS, Pellikka PA, Gulati R, Gochanour BR, Barrett-O'Keefe Z, Raphael CE, Best PJM, Hayes SN. Coronary Artery Tortuosity and Spontaneous Coronary Artery Dissection: Association With Echocardiography and Global Longitudinal Strain, Fibromuscular Dysplasia, and Outcomes. J Am Soc Echocardiogr. 2024 May;37(5):518-529. doi: 10.1016/j.echo.2024.02.013. Epub 2024 Mar 11. PMID: 38467311; PMCID: PMC11605948. Tweet MS, Hayes SN, Grimaldo ABG, Rose CH. Pregnancy After Spontaneous Coronary Artery Dissection: Counseling Patients Who Intend Future Pregnancy. JACC Adv. 2023 Dec;2(10):100714. doi: 10.1016/j.jacadv.2023.100714. Epub 2023 Nov 14. PMID: 38915307; PMCID: PMC11194843. Tarabochia AD, Tan NY, Lewis BR, Slusser JP, Hayes SN, Best PJM, Gulati R, Deshmukh AJ, Tweet MS. Association of Spontaneous Coronary Artery Dissection With Atrial Arrhythmias. Am J Cardiol. 2023 Jan 1;186:203-208. doi: 10.1016/j.amjcard.2022.09.032. Epub 2022 Oct 31. PMID: 36328832; PMCID: PMC10403149. Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Lu Y, Spatz ES, Gupta A, Khera R, Ng VG, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience). Am J Cardiol. 2022 Jun 15;173:33-38. doi: 10.1016/j.amjcard.2022.03.005. Epub 2022 Mar 29. PMID: 35365290; PMCID: PMC9133198. Johnson AK, Tweet MS, Rouleau SG, Sadosty AT, Hayes SN, Raukar NP. The presentation of spontaneous coronary artery dissection in the emergency department: Signs and symptoms in an unsuspecting population. Acad Emerg Med. 2022 Apr;29(4):423-428. doi: 10.1111/acem.14426. Epub 2021 Dec 26. PMID: 34897898; PMCID: PMC10403148. Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Khera R, Lu Y, Spatz ES, Ng VG, Gupta A, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience. PLoS One. 2022 Mar 23;17(3):e0265624. doi: 10.1371/journal.pone.0265624. PMID: 35320296; PMCID: PMC8942215. Adlam D, Tweet MS, Gulati R, Kotecha D, Rao P, Moss AJ, Hayes SN. Spontaneous Coronary Artery Dissection: Pitfalls of Angiographic Diagnosis and an Approach to Ambiguous Cases. JACC Cardiovasc Interv. 2021 Aug 23;14(16):1743-1756. doi: 10.1016/j.jcin.2021.06.027. PMID: 34412792; PMCID: PMC8383825. Kok SN, Tweet MS. Recurrent spontaneous coronary artery dissection. Expert Rev Cardiovasc Ther. 2021 Mar;19(3):201-210. doi: 10.1080/14779072.2021.1877538. Epub 2021 Feb 26. PMID: 33455483. Campbell KH, Tweet MS. Coronary Disease in Pregnancy: Myocardial Infarction and Spontaneous Coronary Artery Dissection. Clin Obstet Gynecol. 2020 Dec;63(4):852-867. doi: 10.1097/GRF.0000000000000558. PMID: 32701519; PMCID: PMC10767871. Tweet MS, Young KA, Best PJM, Hyun M, Gulati R, Rose CH, Hayes SN. Association of Pregnancy With Recurrence of Spontaneous Coronary Artery Dissection Among Women With Prior Coronary Artery Dissection. JAMA Netw Open. 2020 Sep 1;3(9):e2018170. doi: 10.1001/jamanetworkopen.2020. PMID: 32965500; PMCID: PMC7512056. Hayes SN, Tweet MS, Adlam D, Kim ESH, Gulati R, Price JE, Rose CH. Spontaneous Coronary Artery Dissection: JACC State-of-the-Art Review. J Am Coll Cardiol. 2020 Aug 25;76(8):961-984. doi: 10.1016/j.jacc.2020.05.084. PMID: 32819471. Johnson AK, Hayes SN, Sawchuk C, Johnson MP, Best PJ, Gulati R, Tweet MS. Analysis of Posttraumatic Stress Disorder, Depression, Anxiety, and Resiliency Within the Unique Population of Spontaneous Coronary Artery Dissection Survivors. J Am Heart Assoc. 2020 May 5;9(9):e014372. doi: 10.1161/JAHA.119.014372. Epub 2020 Apr 28. PMID: 32342736; PMCID: PMC7428589. Tweet MS, Akhtar NJ, Hayes SN, Best PJ, Gulati R, Araoz PA. Spontaneous coronary artery dissection: Acute findings on coronary computed tomography angiography. Eur Heart J Acute Cardiovasc Care. 2019 Aug;8(5):467-475. doi: 10.1177/2048872617753799. Epub 2018 Jan 29. PMID: 29376398; PMCID: PMC6027604. Tan NY, Tweet MS. Spontaneous coronary artery dissection: etiology and recurrence. Expert Rev Cardiovasc Ther. 2019 Jul;17(7):497-510. doi: 10.1080/14779072.2019.1635011. Epub 2019 Jul 5. PMID: 31232618. Waterbury TM, Tweet MS, Hayes SN, Eleid MF, Bell MR, Lerman A, Singh M, Best PJM, Lewis BR, Rihal CS, Gersh BJ, Gulati R. Early Natural History of Spontaneous Coronary Artery Dissection. Circ Cardiovasc Interv. 2018 Sep;11(9):e006772. doi: 10.1161/CIRCINTERVENTIONS.118. PMID: 30354594. Hayes SN, Kim ESH, Saw J, Adlam D, Arslanian-Engoren C, Economy KE, Ganesh SK, Gulati R, Lindsay ME, Mieres JH, Naderi S, Shah S, Thaler DE, Tweet MS, Wood MJ; American Heart Association Council on Peripheral Vascular Disease; Council on Clinical Cardiology; Council on Cardiovascular and Stroke Nursing; Council on Genomic and Precision Medicine; and Stroke Council. Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association. Circulation. 2018 May 8;137(19):e523-e557. doi: 10.1161/CIR.0000000000000564. Epub 2018 Feb 22. PMID: 29472380; PMCID: PMC5957087. Tweet MS, Kok SN, Hayes SN. Spontaneous coronary artery dissection in women: What is known and what is yet to be understood. Clin Cardiol. 2018 Feb;41(2):203-210. doi: 10.1002/clc.22909. Epub 2018 Mar 1. PMID: 29493808; PMCID: PMC5953427. Tweet MS, Codsi E, Best PJM, Gulati R, Rose CH, Hayes SN. Menstrual Chest Pain in Women With History of Spontaneous Coronary Artery Dissection. J Am Coll Cardiol. 2017 Oct 31;70(18):2308-2309. doi: 10.1016/j.jacc.2017.08.071. PMID: 29073960; PMCID: PMC5957076. Lindor RA, Tweet MS, Goyal KA, Lohse CM, Gulati R, Hayes SN, Sadosty AT. Emergency Department Presentation of Patients with Spontaneous Coronary Artery Dissection. J Emerg Med. 2017 Mar;52(3):286-291. doi: 10.1016/j.jemermed.2016.09. Epub 2016 Oct 8. PMID: 27727035. Tweet MS, Gulati R, Williamson EE, Vrtiska TJ, Hayes SN. Multimodality Imaging for Spontaneous Coronary Artery Dissection in Women. JACC Cardiovasc Imaging. 2016 Apr;9(4):436-50. doi: 10.1016/j.jcmg.2016.01.009. PMID: 27056163. Tweet MS, Gulati R, Hayes SN. What Clinicians Should Know Αbout Spontaneous Coronary Artery Dissection. Mayo Clin Proc. 2015 Aug;90(8):1125-30. doi: 10.1016/j.mayocp.2015.05.010. PMID: 26250728. Prasad M, Tweet MS, Hayes SN, Leng S, Liang JJ, Eleid MF, Gulati R, Vrtiska TJ. Prevalence of extracoronary vascular abnormalities and fibromuscular dysplasia in patients with spontaneous coronary artery dissection. Am J Cardiol. 2015 Jun 15;115(12):1672-7. doi: 10.1016/j.amjcard.2015.03.011. Epub 2015 Mar 23. PMID: 25929580. Goel K, Tweet M, Olson TM, Maleszewski JJ, Gulati R, Hayes SN. Familial spontaneous coronary artery dissection: evidence for genetic susceptibility. JAMA Intern Med. 2015 May;175(5):821-6. doi: 10.1001/jamainternmed.2014. PMID: 25798899. Liang JJ, Prasad M, Tweet MS, Hayes SN, Gulati R, Breen JF, Leng S, Vrtiska TJ. A novel application of CT angiography to detect extracoronary vascular abnormalities in patients with spontaneous coronary artery dissection. J Cardiovasc Comput Tomogr. 2014 May-Jun;8(3):189-97. doi: 10.1016/j.jcct.2014.02.001. Epub 2014 Apr 4. PMID: 24939067. Tweet MS, Hayes SN, Pitta SR, Simari RD, Lerman A, Lennon RJ, Gersh BJ, Khambatta S, Best PJ, Rihal CS, Gulati R. Clinical features, management, and prognosis of spontaneous coronary artery dissection. Circulation. 2012 Jul 31;126(5):579-88. doi: 10.1161/CIRCULATIONAHA.112. Epub 2012 Jul 16. PMID: 22800851. Tweet MS, Gulati R, Aase LA, Hayes SN. Spontaneous coronary artery dissection: a disease-specific, social networking community-initiated study. Mayo Clin Proc. 2011 Sep;86(9):845-50. doi: 10.4065/mcp.2011.0312. PMID: 21878595; PMCID: PMC3257995.   WANT TO WORK AT MAYO? EM Physicians: https://jobs.mayoclinic.org/emergencymedicine EM NP PAs: https://jobs.mayoclinic.org/em-nppa-jobs   Nursing/Techs/PAC: https://jobs.mayoclinic.org/Nursing-Emergency-Medicine EMTs/Paramedics: https://jobs.mayoclinic.org/ambulanceservice All groups above combined into one link: https://jobs.mayoclinic.org/EM-Jobs

This Week in Review covers 5 episodes from October 27 to October 31, featuring major developments in the pharmaceutical and biotech industries.Episodes included:1. Pharma Shifts: Dual-Action Obesity Drugs & Regulatory Waves2. Navigating Pharma's New Frontiers: Breakthroughs and Challenges3. Gene Therapy Challenges and Regulatory Shifts: Industry Innovations4. Biotech Breakthroughs: Transformative Acquisitions and FDA Milestones5. Novartis' $12B RNA Therapeutics BreakthroughKey topics covered:- Strategic acquisitions and partnerships- Regulatory updates and FDA approvals- Clinical trial results and breakthroughs- Industry trends and market developmentsStay informed with Pharma Daily's comprehensive coverage of the pharmaceutical and biotech world.Support the show

Clinical psychologist and ACT expert Diana Hill returns to help us do what feels nearly impossible in a loud, burned-out world—focus our energy where it actually matters. We talk psychological flexibility, why curiosity beats quick answers, and how “positive energizers” can lift a whole family system. Diana explains neuroception and interoception in everyday terms, then makes it practical: hum to downshift your nervous system, rub your palms and rest them over your eyes, take a short walk outside, and remember that sometimes you can't think your way out—you have to move your way out. Along the way, we explore why nature reliably restores attention and creativity, and how parents can help kids build real-life wisdom that no app can deliver. Drawing from her new book Wise Effort, Diana shares the simple moves that metabolize stress hormones and turn big feelings into forward motion (plus the story behind her own “get unstuck button.”) We dig into genius energy, the shadow side of our strengths, and how tiny, values-aligned experiments shift relationships, work, and family life. If you're overcommitted yet under-involved, this conversation is your trailhead back to presence, purpose, and playful resilience. Get your copy of I Know I Should Exercise But... here Learn more about your ad choices. Visit megaphone.fm/adchoices

Send me a DM here (it doesn't let me respond), OR email me: imagineabetterworld2020@gmail.comToday I'm honored to introduce you to: Owner and founder of Koinonia Counseling Center, Licensed Professional Counselor, ISSTD member, survivor advocate, support, and helper, content creator, educator., proud wife and loving mother, documentary and true crime lover, and a woman single-handedly changing how the world sees and understands Dissociative Identity Disorder: Sara Rice M.A., LPC-SSara is a compassionate and dedicated professional mental health counselor whose life's work centers on empowering survivors and fostering healing in those facing profound challenges. As a certified supervisor for Licensed Professional Counselors (LPCs) and the proud wife of an Army Veteran for over a decade, Sara brings a deep well of empathy and resilience to her practice. A mother of five children, she balances her bustling family life with an unwavering commitment to her clients and her ongoing pursuit of knowledge. Sara earned her Master's degree in Counseling from Liberty University and is currently working toward a doctorate in Traumatology, reflecting her relentless drive to deepen her expertise in trauma and mental health. With a trauma-informed approach, Sara's practice is a sanctuary for survivors, offering hope and guidance to those who have endured unimaginable hardships. Her ability to connect with clients stems from her deep understanding of the complexities of mental health and her genuine care for each individual's journey. Sara's work is not just a profession - it's a calling to uplift, empower, and restore.I personally met Sara on TikTok, where her account graced my For You Page and I immediately followed and binged her page. I was so impressed by her work, the content she was creating around such a difficult topic, and her clear passion for her work and clients, that I contacted and asked her to be on this podcast so we could all learn from her - and was so grateful she agree to come on. Her understanding of the complexities of DID, compassion for the RAMCOA community, and her courage to be speaking publicly about these topics that few in her field will touch make her a hero in my eyes, someone who deserves our support, and someone we can all benefit to learn from.Sara is far more than a counselor; she is a radiant force of hope, a tireless advocate, and a living testament to the transformative power of compassion. Through her work at KCC PLLC, she lights the way for those navigating the deepest shadows of their minds, offering not just solace but a path to empowerment and renewal. Her dedication to survivors is a clarion call to the resilience of the human spirit, reminding us all that even in the face of profound pain, there is always a way forward. With every client she supports, every story she hears, and every life she touches.CONNECT WITH SARA: Website: https://www.kccpllc.com/#/TikTok: https://www.tiktok.com/@koinoniacounselingcenter?lang=enCONNECT WITH EMMA / THE IMAGINATION: YouTube: https://www.youtube.com/@imaginationpodcastofficialRumble: https://rumble.com/c/TheImaginationPodcastEMAIL: imagineabetterworld2020@gmail.com OR standbysurvivors@protonmail.comMy Substack: https://emmakatherine.substack.com/BUY ME A COFFEE: https://www.buymeacoffee.com/theimaginationVENMO: @emmapreneurCASupport the show

Every therapist can talk for days about difficult cases. But what about the cases that work? In this episode, Paul and Ray break down how success leaves clues — from therapist strengths to client readiness to the role of meaning and expert identity in change. You'll learn how to reflect on what actually makes you effective, reshape your marketing to match your true impact, and confidently choose the right clinical fits instead of taking every referral that comes your way. Whether you're building a caseload or rebuilding one, this conversation helps you practice with energy, alignment, and purpose.For more than 45 years, PAR has been publishing trusted assessment instruments that help their customers in the crucial work they perform every day. Their U.S.-based, company is a talented group of professionals who are guided by their desire to create tools that help their customers improve the lives of those they serve.To hear more and stay up to date with Paul Wagner, MS, LPC and Ray Christner, Psy.D., NCSP, ABPP visit our website at: http://www.psychedtopractice.com Please follow the link below to access all of our hosting sites. https://www.buzzsprout.com/2007098/share “Be well, and stay psyched" #mentalhealth #podcast #psychology #psychedtopractice #counseling #socialwork #MentalHealthAwareness #ClinicalPractice #mentalhealth #podcast

How we show up to treat our patients as a dental hygienist is up to us. We can make or break our own day when we show up with the wrong mindset or negative self-sabotage. I compiled a list of things that have really helped my clinical days as a dental hygienist. It can be one of those careers that produce significant early career burnout and dissatisfaction - if you are not careful.I worked for almost thirty years as a dental hygienist. Some of the things on my list were the primary reasons behind how I was able to overcome the limits and remain grateful for the ability to perform the job. I love this profession, and I want others to see the value it can bring to your soul - if you take the time to look at things the way they can be seen. Additional resources:Tutoring with Me: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://calendly.com/d/cszb-s4r-hy4/tutoring-with-billie⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Leave me a message or send a question I can share on the Podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Time Management Prioritization Quiz - Find out how you rate ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠HERE ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Study Sheets: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://thehappyflosserrdh.etsy.com/ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Specialized Course: How to be successful in Dental Hygiene School⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://billie-lunt-s-school.teachable.com/p/how-to-be-successful-in-dental-hygiene-school⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Other Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠blog.feedspot.com/dental_hygiene_podcasts/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  Email Me: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠HappyflosserRDH@gmail.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Leave me a message or ask a question I can share on the Podcast ⁠⁠⁠⁠⁠⁠⁠⁠Here ⁠⁠⁠⁠⁠⁠⁠⁠Time Management Prioritization Quiz - Find out how you rate ⁠⁠⁠⁠⁠⁠⁠⁠⁠HERE ⁠⁠⁠⁠⁠⁠⁠⁠Check out my free scorecard for students - you can rank yourself on how you are doing to take action on the steps toward being a successful college student. Sign up on the Google doc ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠HERE⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ - I will send along your scorecard to use the entire time you are enrolled in school. Study Sheets: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://thehappyflosserrdh.etsy.com/ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Specialized Course: How to be successful in Dental Hygiene School⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://billie-lunt-s-school.teachable.com/p/how-to-be-successful-in-dental-hygiene-school⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Other Podcasts: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠blog.feedspot.com/dental_hygiene_podcasts/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Tooth fairy escape room ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Here ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email Me: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠HappyflosserRDH@gmail.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Billie Lunt Media Kit: ⁠⁠⁠⁠⁠⁠⁠⁠https://www.canva.com/design/DAGaiUvmKTI/R8NEtEIUAwS9pptthWb6QQ/view?utm_content=DAGaiUvmKTI&utm_campaign=designshare&utm_medium=link2&utm_source=uniquelinks&utlId=hb5fb9186b2⁠⁠⁠⁠⁠⁠⁠

Dr. Sterling Elliott, Clinical pharmacist at Northwestern Medicine and assistant professor of orthopaedics at Feinberg School of Medicine, joins Lisa Dent to discuss a recall on a widely used blood pressure medication. Prazosin Hydrochloride, a medication used for blood pressure, has been voluntarily recalled by Teva Pharmaceuticals USA Inc. impacting in more than half a […]

Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. Following the 2025 Alzheimer's Association International Conference (AAIC), Rebecca Edelmayer, PhD, outlines the Alzheimer's Association's first clinical practice guidelines for using blood-based biomarkers (BBMs) in the diagnostic workup of suspected Alzheimer's disease within specialized care. She explains the guideline mission, how tests were evaluated for accuracy, and when BBMs should serve as triage versus confirmatory tools relative to CSF and PET. Edelmayer details current scope limits (cognitively impaired patients in specialty settings), cautions against overextending to primary care or unimpaired populations, and previews the education roll-out—executive summaries, micro-learning modules, and shared decision-making resources. She closes with research priorities: stronger peer-reviewed reporting, broader validation across diverse populations and settings, and building an equitable pathway that leverages BBMs to speed accurate diagnosis and treatment access. Looking for more Alzheimer & dementia discussion? Check out the NeurologyLive® Alzheimer & dementia clinical focus page. Episode Breakdown: 1:05 – Understanding the purpose and mission behind new blood-based biomarker guidelines 2:05 – Key recommendations and defining triage vs confirmatory blood-based biomarker use 3:15 – Clinical precautions and where blood-based biomarkers are appropriate today 5:30 – Neurology News Minute 7:45 – Educating clinicians on implementing BBMs in specialty care 10:15 – Research priorities to strengthen evidence and ensure equity The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: FDA Accepts New Drug Application for Tau PET Imaging Agent MK-6240 in Alzheimer Disease B-Cell Modulator Obexelimab Shows Pronounced Relapse Reduction in Phase 2 MoonStone Trial Subcutaneous Efgartigimod Shows Efficacy in Phase 2 ALKIVIA, Phase 3 ADAPT SERON Trials Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.

Vidcast:  https://www.instagram.com/p/DQdod3Mj3HW/A new, supercharged form of immunotherapy for breast cancer has just been announced by UCLA oncologists in the Journal of Hematology & Oncology. The new approach involves the production of CAR-NKT cells, standing for chimeric antigen receptor-natural killer T cells, that have the superpower to attack not one but dozens of tumor cell surface antigens simultaneously.  The cells target a protein mesothelin, which cancers need to rapidly grow and spread.Many current immunotherapies only target a single receptor. Triple negative breast cancers lack many of these common receptors making them difficult to treat successfully. This CAR-NKT therapy attacks so many receptors it could prove effective for those with these triple negative cancers.Even better, the CAR-NKT cells can be mass-produced from donated stem cells and stored for immediate use on demand. Very promising is the fact that the CAR-NKT cells target, mesothelin, is not only found on breast cancers but also on the surfaces of ovarian, pancreatic, and lung cancer cells.So far, these CAR-NKT cells have only been tested in the laboratory on tissue cultured breast cancer cells harvested from patient swith advanced disease.  Clinical trials are in the planning stages, and hopefully, this super-immunotherapy will be available to save patients with a variety of difficult-to-treat cancers…..someday soon.https://www.news-medical.net/news/20251022/New-type-of-immunotherapy-could-change-the-treatment-plan-for-triple-negative-breast-cancer.aspxhttps://jhoonline.biomedcentral.com/articles/10.1186/s13045-025-01736-9#immunotherapy #CAR-NKT #cancer #breast #triplenegative #ovarian #pancreatic #lung

How do you redefine a field that's widely misunderstood, even among its own professionals? And how can associations become essential hubs for interdisciplinary collaboration in such a space?In this episode of Associations Thrive, host Joanna Pineda interviews Nathan Victoria, Executive Director of the Society for Personality Assessment (SPA) and Vice President at NextGen Association Management. Nathan discusses:Why “personality assessment” doesn't mean pop personality tests like Myers-Briggs or StrengthsFinder, but instead refers to integrated and multi-method clinical assessments used by psychologists.The clinical and legal applications of personality assessment, including for law enforcement, immigration, air traffic controllers, and reality TV casting.SPA's historical roots as the Rorschach Institute, Inc., and how it's evolving to reclaim and redefine personality assessment.The effort to define personality assessment within the organization and clarify its public perception.SPA's reinvestment in infrastructure: website, branding, database, and strategic plan.The organization's shift to AMC management through NextGen, and the benefits of a more efficient staffing model.How SPA supports international engagement with its first-ever conference outside the U.S., despite visa and travel challenges.SPA's unique conference partnerships with smaller psychology organizations to share resources and cross-pollinate ideas.Nathan's broader role in managing multiple associations simultaneously through NextGen and how technology and transparency enable success.References:SPA WebsiteNextGen AMC Website2025 Expert Insights on Personality Assessment Virtual Conference2026 SPA Convention

Howie and Harlan are joined by Nate Wood, a Yale School of Medicine internist and trained chef, to discuss his work combining lifestyle guidance with hands-on training in making healthy, tasty food. Harlan shares new guidance on what counts as a healthy blood pressure; Howie provides an update on rising health insurance costs. Links: Blood Pressure Harlan Kumholz, "Severe Hypertension: The Next Never Event" JACC: 2025 High Blood Pressure Guidelines Resources "Trial of Intensive Blood-Pressure Control in Older Patients with Hypertension" Obesity Drugs "Semaglutide and Tirzepatide for Obesity: Effectiveness and Value" "Institute for Clinical and Economic Review Publishes Evidence Report on Treatments for Obesity" Harlan Krumholz and Jason Abaluck, "Changes in Cardiovascular Risk Factors and Health Care Expenditures Among Patients Prescribed Semaglutide" Culinary Medicine "Culinary Medicine: The Secret Ingredient to Good Health" American College of Lifestyle Medicine "How each lifestyle medicine pillar supports good nutrition" Dr. John La Puma "What to know about 'hyperpalatable' foods" Food is Medicine Coalition: Our Model American Academy of Family Physicians: Shared Medical Appointments/Group Visits Cleveland Clinic: GLP-1 Agonists Yale New Haven Hospital: Irving and Alice Brown Teaching Kitchen "Bringing Culinary Medicine to Yale's New Teaching Kitchen" Dr. Nate Wood Nate Wood on Instagram Health Insurance Costs Kaiser Family Foundation: 2025 Employer Health Benefits Survey "Health Benefits In 2025: Family Premiums Rise 6 Percent, Large Employers Increase Coverage Of GLP-1s For Weight Loss" "Annual Family Premiums for Employer Coverage Rise 6% in 2025, Nearing $27,000, with Workers Paying $6,850 Toward Premiums Out of Their Paychecks" "8 Things to Watch for the 2026 ACA Open Enrollment Period" "ACA Insurers Are Raising Premiums by an Estimated 26%, but Most Enrollees Could See Sharper Increases in What They Pay" Learn more about the MBA for Executives program at Yale SOM. Email Howie and Harlan comments or questions.

Today, we're tackling a question that comes up often in peptide, weight loss, and nutrition clinics: why does one person see great results with semaglutide, while another responds better to tirzepatide—or even retatrutide? If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. https://pepties.com/partners/ All three peptides target the incretin system, but they act in slightly different ways—and those differences can dramatically affect outcomes. Let's start with the basics. Semaglutide is a GLP-1 (glucagon-like peptide-1) receptor agonist. It mimics the gut hormone GLP-1, which increases insulin when blood sugar is high (to help lower blood sugar), suppresses glucagon (which also decreases blood sugar), and slows gastric emptying. It also enhances satiety—so you feel full longer and eat less. Tirzepatide is a dual agonist, acting on both GLP-1 and GIP receptors. GIP—glucose-dependent insulinotropic polypeptide—also helps with insulin secretion to lower blood sugar, increases fat metabolism, and may reduce some of the GI side effects seen with GLP-1 alone. Retatrutide, the newest in the lineup, is a triple agonist that targets GLP-1, GIP, and glucagon receptors. Retatrutide lightly activates the glucagon receptor while strongly activating GLP-1 and GIP receptors, which help regulate blood sugar and boost insulin secretion. This keeps blood sugar stable—or even improves it. Beyond blood sugar, glucagon also ramps up metabolism and calorie burning. By gently engaging glucagon receptors, retatrutide can increase energy expenditure and support fat loss without triggering large blood sugar spikes. So how do you decide which one might work best? Let's walk through common clinical situations. Patients with Hypothyroidism Let's talk about hypothyroidism. People with hypothyroidism often have slower metabolism, making weight loss more difficult even with a balanced diet. Low thyroid hormone levels slow calorie burning and energy use, so weight gain can occur more easily. For these patients, semaglutide is a reliable starting point—it helps regulate appetite and caloric intake. If progress plateaus, tirzepatide or retatrutide may provide an edge by boosting energy expenditure and fat oxidation, essentially "jump-starting" a slower metabolism. Patients with PCOS (Polycystic Ovary Syndrome) What about patients with PCOS (polycystic ovary syndrome)? Insulin resistance is common in PCOS, often leading to higher androgen levels (e.g., testosterone) and symptoms like irregular periods, acne, and excess hair growth. Hormonal changes also affect appetite-regulating hormones, increasing hunger and cravings. Both GLP-1 and dual agonists have proven effective in managing metabolic and reproductive aspects of PCOS. Typically, we start with semaglutide to improve weight, insulin sensitivity, androgen levels, and menstrual regularity. After a few months, if weight loss plateaus or cravings remain high, we may switch to tirzepatide. The added GIP activity enhances fat metabolism, insulin control, and may further support hormone regulation and ovulation. The key is starting with what's well-studied and tolerated, then stepping up if additional metabolic or reproductive support is needed. Type 2 Diabetes (T2DM) The next medical condition I'd like to talk about is type 2 diabetes (T2DM). Weight gain in T2DM often stems from insulin resistance. Cells don't respond effectively to insulin, prompting the pancreas to relelase more. High insulin levels encourage fat storage, particularly around the abdomen, while elevated blood sugar can increase hunger and cravings. Some diabetes medications, like insulin or sulfonylureas (e.g., glipizide or glyburide), can also contribute to weight gain. All three drugs lower blood sugar and promote weight loss, but tirzepatide currently shows the strongest combined A1c reduction (average blood sugar over the past 2 to 3 months) and weight loss. GIP and GLP-1 work together to enhance insulin response more effectively than GLP-1 alone. Retatrutide is in phase 3 trials, with potential FDA approval as early as 2027. Its glucagon receptor activity may offer additional glucose regulation and energy expenditure benefits. Patients with >15% Weight Loss Goals Okay, let's talk about weight loss goals and how this ties into the decision process for choosing a weight loss medication. For those patients looking to lose more than 15% of their total body weight, tirzepatide or retatrutide are likely to deliver greater results. Clinical data show semaglutide can achieve up to 15% total weight loss while tirzepatide can achieve up to 22% and retatrutide up to 24%. That said, semaglutide remains a highly effective option for weight loss. However, if progress begins to plateau, transitioning to a dual or triple agonist may help restart weight loss and push past that plateau. Pre- and Postmenopausal Women What about peri- and postmenopausal patients? Hormonal shifts during perimenopause and menopause slow metabolism and can increase cravings. Declining estrogen promotes abdominal fat storage and affects appetite-regulating hormones. Semaglutide helps with appetite control and gradual fat loss, while tirzepatide's GIP activation can further support fat metabolism when estrogen levels drop. Patients with Heart Disease or High Cholesterol The last group of patients I'd like to discuss is patients with heart disease (e.g., heart failure, stroke, heart attack, or even atherosclerosis) or people with high cholesterol. Semaglutide has the strongest cardiovascular outcomes data, reducing major adverse cardiac events by 20% and improving LDL cholesterol (bad cholesterol) and blood pressure. Tirzepatide shows promise for heart and lipid benefits, but those trials are still ongoing. For patients with prior heart attack, stroke, or severe coronary artery disease, semaglutide remains the safest evidence-backed starting point—unless intolerable side effects or weight loss resistance occur. Tolerability Now I want to switch gears a bit and talk about side effects and tolerablity of these peptides. Some patients experience stomach-related side effects like nausea, bloating, or acid reflux on semaglutide. Generally, tirzepatide tends to cause fewer GI side effects, likely due to GIP balancing GLP-1 activity in the gut. So patients struggling with nausea or other stomach-related side effects may find tirzepatide more tolerable. Just something to keep in mind. Individualizing Therapy Lastly, I want to highlight the importance of individualizing weight loss peptide treatments. There's no one-size-fits-all approach when it comes to these therapies. Clinicians should carefully consider a patient's goals, medical history, current medications, and tolerance before choosing the most appropriate option. Setting realistic expectations from the start is essential. It's important to remember that everyone's body responds differently because of factors like hormones, genetics, metabolism, gut microbiome balance, and lifestyle habits. These differences influence how effectively a peptide therapy works and how well it's tolerated. That's why ongoing monitoring and follow-up are such an important part of the process. Providers track progress, adjust dosing when needed, and switch medications if weight loss plateaus or side effects occur. The goal isn't just to lose weight quickly—it's to create a safe, sustainable plan that supports long-term metabolic health and helps patients feel their best. Thanks for listening to The Peptide Podcast.  If you want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. Until next time, be well, and have a happy, healthy week.

Alyssa Mack, PharmD, joined Over the Counter during American Pharmacists Month to discuss how her pharmacy practice has put a focus on increasing clinical services.

Clinical psychologist Dr. Anne Louise Lockhart breaks down what teens are really communicating beneath their behavior, and why connection—not control—matters most. We discuss key insights from her new book Love the Teen You Have and how reframing “conflict” can strengthen any relationship.15 Daily Steps to Lose Weight and Prevent Disease PDF: https://bit.ly/46XTn8f - Get my FREE eBook now!Subscribe to The Genius Life on YouTube! - http://youtube.com/maxlugavereWatch my new documentary Little Empty Boxes - https://www.maxlugavere.com/filmThis episode is proudly sponsored by:BUBS Naturals makes my favorite collagen, pure and unflavored, perfect for mixing into any drink, soup, or even recipes! Your hair, skin, and nails will thank you. Visit BUBSNaturals.com and use code GENIUS for 20% off.Boost nutrient absorption with LivOn Labs. For a limited time, order one carton of Lypo-Spheric Vitamin C at LivOnLabs.com and get one carton of Lypo-Spheric B Complex Plus FREE—a $56 value—with code MAX25 at checkout!OneSkin is a skincare company for minimalists utilizing their revolutionary OS-01 peptide which can reverse signs of skin aging according to their research. Visit ⁠http://oneskin.co/max⁠ and use code MAX for 15% off.

Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Dr. Andrew Lee, Vice President, Clinical Research at Uniquity Bio, about Thymic Stromal Lymphopoietin (TSLP) and eosinophilic esophagitis (EOE). Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.   Key Takeaways: [:49] Co-host Ryan Piansky introduces the episode, brought to you thanks to the support of Education Partners Bristol Myers Squibb, GSK, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz.   [1:13] Holly introduces today's topic, Thymic Stromal Lymphopoietin (TSLP) and eosinophilic esophagitis (EOE), and today's guest, Dr. Andrew Lee, Vice President, Clinical Research at Uniquity Bio.   [1:36] Dr. Lee has nearly 20 years of experience in the clinical development of new vaccines, biologics, and drugs. Holly welcomes Dr. Lee.   [1:52] Dr. Lee trained in internal medicine and infectious diseases.   [1:58] Dr. Lee has been fascinated by the immune system and how it can protect people against infections, what happens when immunity is damaged, as in HIV and AIDS, and how to apply that knowledge to boost immunity with vaccines to prevent infections.   [2:16] Dr. Lee led the clinical development for a pediatric combination vaccine for infants and toddlers. It is approved in the U.S. and the EU.   [2:29] Dr. Lee led the Phase 3 Program for a monoclonal antibody to prevent RSV, a serious infection in infants. That antibody was approved in June 2025 for use in the U.S.   [2:44] In his current company, Dr. Lee leads research into approaches to counteract an overactive immune system. They're looking at anti-inflammatory approaches to diseases like asthma, EoE, and COPD.   [2:58] Dr. Lee directs the ongoing Phase 2 studies that they are running in those areas.   [3:28] Dr. Lee sees drug development as a chance to apply cutting-edge research to benefit people. He trained at Bellevue Hospital in New York City in the 1990s.   [3:40] When Dr. Lee started as an intern, there were dedicated ICU wards for AIDS patients because many of the sickest patients were dying of AIDS and its complications.    [3:52] Before the end of Dr. Lee's residency, they shut down those wards because the patients were on anti-retroviral medications and were doing so well that they were treated as outpatients. They didn't need dedicated ICUs for AIDS patients anymore.   [4:09] For Dr. Lee, that was a powerful example of how pharmaceutical research and drug regimen can impact patients' lives for the better by following the science. That's what drove Dr. Lee to go in the direction of research.   [4:48] Dr. Lee explains Thymic Stromal Lymphopoietin (TSLP). TSLP serves as an alarm signal for Type 2 or TH2 inflammation, a branch of the immune responses responsible for allergic responses and also immunity against parasites.   [5:17] When the cells that line the GI tract and the cells that line the airways in our lungs receive an insult or an injury, they get a danger signal, then they make TSLP.   [5:28] This signal activates other immune cells, like eosinophils and dendritic cells, which make other inflammatory signals or cytokines like IL-4, IL-13, and IL-5.   [5:47] That cascade leads to inflammation, which is designed to protect the body in response to the danger signal, but in some diseases, when there's continued exposure to allergens or irritants, that inflammation goes from being protective to being harmful.   [6:15] That continued inflammation, over the years, can lead to things like the thickened esophagus with EoE, or lungs that are less pliant and less able to expand, in respiratory diseases.   [6:48] Dr. Lee says he thinks of TSLP as being a master switch for this branch of immune responses. If you turn on TSLP, that turns on a lot of steps that lead to generating an allergic type of response.   [7:06] It's also the same type of immune response that can fight off parasite infections. It's the first step in a cascade of other steps generating that type of immune response.   [7:30] Dr. Lee says people have natural genetic variation in the genes that incur TSLP.   [7:38] Observational studies have found that some people with genetic variations that lead to higher levels of TSLP in their bodies had an increased risk for allergic inflammatory diseases like EoE, atopic dermatitis, and asthma.   [8:13] Studies like the one just mentioned point to TSLP being important for increased risk of developing atopic types of diseases like EoE and others. There's been some work done in the laboratory that shows that TSLP is important for activating eosinophils.    [8:38] There's accumulating evidence that TSLP activation leads to eosinophil activation, other immune cells, or white blood cells getting activated.   [9:07] Like a cascade, those cells turn on T-cells and B-cells, which are like vector cells. They lead to direct responses to fight off infections, in case that's the signal that leads to the turning on TSLP.   [9:48] Ryan refers to a paper published in the American Journal of Gastroenterology exploring the role of TSLP in an experimental mouse model of eosinophilic esophagitis. Ryan asks what the researchers were aiming to find.   [10:00] Dr. Lee says the researchers were looking at the genetic studies we talked about, the observational studies that are beginning to link more TSLP with more risk for EoE and those types of diseases.   [10:12] The other type of evidence that's accumulating is from in vitro (in glass) experiments or test tube experiments, where you take a couple of cells that you think are relevant to what's going on.   [10:28] For example, you could get some esophageal cells and a couple of immune cells, and put TSLP into the mix, and you see that TSLP leads to activation of those immune cells and that leads to some effects on the esophageal cells.   [10:42] Those are nice studies, but they're very simplified compared to what you can do in the body. These researchers were interested in extending those initial observations from other studies, but working in the more realistic situation of a mouse model.   [11:00] You have the whole body of the mouse being involved. You can explore what TSLP is doing and model a disease that closely mimics what's happening with EoE in humans.   [12:23] They recreated the situation of what seems to be happening in EoE in people. We haven't identified it specifically, but there's some sort of food allergen in patients with EoE that the immune system is set off by.   [12:55] What researchers are observing in this paper is that in these mice that were treated with oxazolone, there is inflammation in the esophagus, an increase in TSLP levels, and eosinophils going into the esophageal tissues.   [13:15] Dr. Lee says, that's one of the main ways we diagnose EoE; we take a biopsy of the esophagus and count how many eosinophils there are. Researchers saw similar findings. The eosinophil count in the esophageal tissues went way up in these mice.    [13:34] Researchers also saw other findings in these mice that are very similar to EoE in humans, such as the esophageal cells lining the esophagus proliferating. They even saw that new blood vessels were being created in that tissue that's getting inflamed.   [14:00] Dr. Lee thinks it's a very nice paper because it shows that correlation: Increase TSLP and you see these eosinophils going to the esophagus, and these changes that are very reminiscent of what we see in people with EoE.   [14:51] In this paper, the mice made the TSLP, and researchers were able to measure the TSLP in the esophageal tissue. The researchers didn't introduce TSLP into the mice. The mice made the TSLP in response to being repeatedly exposed to oxazolone.   [15:20] That's key to the importance of the laboratory work. The fact that the TSLP is made by the mice is important. It makes it a very realistic model for what we're seeing in people.   [15:41] In science, we like to see correlation. The researchers showed a nice correlation.   [15:46] When TSLP went up in these mice, and the mice were making more TSLP on their own, at the same time, they saw all these changes in the esophagus that look a lot like what EoE looks like in people.    [16:01] They saw the eosinophils coming into the esophagus. They saw the inflammation go up in the esophagus. What Dr. Lee liked about this paper is that they continued the story.   [16:15] The researchers took something that decreases TSLP levels, an antibody that binds to and blocks TSLP, and when they did that, they saw the TSLP levels come down to half the peak level.   [16:35] Then they saw improvement in the inflammation in the esophagus. They saw that the amount of eosinophils decreased, and the multiplication of the esophageal cells went down. The number of new blood vessels went down after the TSLP was reduced.   [16:53] Dr. Lee says, you see correlation. The second part is evidence for causation. When you take TSLP away, things get better. That gives us a lot of confidence that this is a real finding. It's not just observational. There is causation evidence here.   [18:26] Ryan asks if cutting TSLP also help reduce other immune response cells. Dr. Lee says TSLP is the master regulator for this Type 2 inflammation. It definitely touches and influences other cells besides eosinophils.   [18:44] TSLP affects dendritic cells, which are an important type of immune cell, like a coordinating cell that instructs other cells within the immune system what to do. In this paper, they looked at a lot of other effects of TSLP on the tissues of the body.   [19:10] Dr. Lee says, There's a lot of research on TSLP, and one of the reasons we're excited about the promise of TSLP is that it's so far upstream; so much of the beginning, that it's affecting other cells.   [19:29] Its effects could be quite broad. If we're able to successfully block TSLP, we could block a lot of different effects.   [19:40] One treatment for EoE is dupilumab, which blocks IL-4 and IL-13 specifically, and that works well, but TSLP has the potential to have an even greater effect than blocking IL-4 and IL-13, since it is one step before turning on IL-4 and IL-13.    [20:14] That's one of the reasons researchers are excited about the promise of blocking TSLP. There are studies ongoing of TSLP blockers in people with EoE.   [20:34] Ryan asks if there are negative repercussions from blocking TSLP. Dr. Lee says in this study and in people, we are not completely blocking TSLP by any means. There will still be residual TSLP activated, even with very potent drugs.   [21:01] In the study, they block TSLP about 50%‒60%. TSLP is involved in immunity against parasites. In studies with people, they make sure not to include anybody who has an active parasitic infection. A person under treatment should not be in a study.   [21:27] Dr. Lee says we haven't seen any problems with parasitic infections becoming more severe, but that is a theoretical possibility, so for that reason, in studies with TSLP blockers, we generally exclude patients with known parasitic infections.   [22:17] What excited Dr. Lee in this paper was that they showed that when you block TSLP in the mice, then you get real effects in their tissues. Eosinophils went away. The thickening of the basal layers in the esophagus got much better.   [22:38] That kind of real effect reflected in the tissue is super exciting to see. That gives us more confidence that this could work in people, since we're seeing it in a realistic whole-body model in the mice.   [23:12] Dr. Lee says there are ongoing clinical studies on TSLP blockers for EoE. His company is studying an antibody that blocks TSLP in eczema, COPD, and EoE. One of the exciting things about immunology is that it affects many different parts of the body.   [23:42] EoE is associated with other immune-type disorders. There's a high percentage of patients with EoE who have other diseases. EoE coexists with asthma, atopic dermatitis, and chronic rhinitis.   [24:09] It's exciting that if you figure out something that's promising for one disease that TSLP affects, it could have very broad-ranging implications for a variety of diseases.   [24:22] Ryan shares his experience of his doctor talking to him about a TSLP blocker, tezepelumab, as a potential option when it's out of clinical trials. It would target something a little higher up the chain and help with some of his remaining symptoms.   [24:59] Ryan is excited to hear that this research is so encouraging and how it could potentially help treat EoE, asthma, and other conditions, all at once.   [25:16] Dr. Lee says that being in these later-stage studies is super exciting. If these late-stage trials are successful, the next step is to apply for regulatory approval with the various agencies around the world.   [26:40] Dr. Lee shares one takeaway for listeners to remember. Think of TSLP as an alarm that turns on inflammation. He compares TSLP to turning on an alarm during a robbery. There are multiple steps designed to protect the bank and the money.   [27:20] To extend that analogy, with TSLP, once you turn it on, all these other steps are going to happen. Inflammation is designed to protect the body. It's a protective response. If there's an infection, it can clear the infection.   [27:38] If the infection persists, as in HIV, the immune response, which is protective and beneficial, eventually becomes damaging. It becomes dysfunctional. In EoE, if you continually eat the allergic food, the inflammation becomes damaging to the esophagus.   [28:27] Long-term inflammation leads to replacing the normal esophageal tissue with fibrotic tissue, and that's why the esophagus eventually gets hardened and less able to let the food go through.   [28:40] In respiratory diseases, the soft tissue of the lung gets replaced with thicker tissue, and the lung is not able to expand.   [28:54] Dr. Lee says he people to think about TSLP as this master alarm switch. We hope that if you could turn off that TSLP, you could then avoid a lot of the complications that we see with chronic inflammation in these conditions.   [29:14] We're hopeful that you could even take away the symptoms that you see in these diseases, make patients feel better, and with extended treatment, you could begin to reverse some of the damage resulting from inflammation.   [29:32] Ryan likes that analogy and how Dr. Lee has concisely explained these complicated concepts.   [29:51] Dr. Lee thanks Holly and Ryan and adds one more plea to listeners. Please consider getting involved with research. Clinical trials cannot be done without patients. We need patients to advance new treatments.   [30:27] Researchers like Dr. Lee spend a lot of time thinking about how to make the studies not only informative but also fair to patients who decide to become involved. It's a lot of work and a fair amount of time commitment.   [30:44] If you don't want to be in a study, you can help by being on a patient feedback panel and reviewing protocols and informed consents. Follow your interests. Think about getting involved with research, however you can.   [31:06] Ryan and Holly are very grateful for the community, with so many wonderful clinicians and researchers, and so many patients who are willing to volunteer their time and their data to help researchers find better solutions going forward.   [31:26] Ryan thanks Dr. Lee for coming on and putting out that call to action. It's a great reminder for listeners and the patients in the community to look for those opportunities. Chat with your physician. Go to APFED's website. There's a link to active clinical trials.   [31:47] For our listeners who want to learn more about eosinophilic disorders, we encourage you to visit apfed.org and check out the links in the show notes below.   [31:53] For those looking to find specialists who treat eosinophilic disorders, we encourage you to use APFED's Specialist Finder at apfed.org/specialist.   [32:01] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at apfed.org/connections.   [32:11] Ryan thanks Dr. Andrew Lee for joining us today. We learned a lot. Holly also thanks APFED's Education Partners Bristol Myers Squibb, GSK, Sanofi, Regeneron, and Takeda for supporting this episode.   Mentioned in This Episode: Andrew Lee, M.D., VP Clinical Research, Uniquity Bio   "A Mouse Model for Eosinophilic Esophagitis (EoE)" Current Protocols, Wiley Online Library   APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections apfed.org/research/clinical-trials   Education Partners: This episode of APFED's podcast is brought to you thanks to the support of Bristol Myers Squibb, GSK, Sanofi, Regeneron, and Takeda.   Tweetables:   "I see drug development as a chance to apply cutting-edge research to benefit people." — Andrew Lee, M.D.   "When the cells that line the GI tract and the cells that line the airways in our lungs receive an insult or an injury, they get a danger signal, then they make TSLP." — Andrew Lee, M.D.   "Observational studies have found that some people with genetic variations that lead to higher levels of TSLP in their bodies had an increased risk for allergic inflammatory diseases like EoE, atopic dermatitis, and asthma." — Andrew Lee, M.D.   "There's a lot of research on TSLP, and one of the reasons we're excited about the promise of TSLP is that it's so far upstream; so much of the beginning, that it's affecting other cells." — Andrew Lee, M.D.   "Please consider getting involved with research. We can't do these clinical trials without patients. We need patients to advance new treatments for patients." — Andrew Lee, M.D.

Does it really matter which type of therapy you choose? In this Mind the Kids episode, hosts Dr. Jane Gilmour and Prof. Umar Toseeb sit down with Professor Ian Goodyer from the University of Cambridge to unpack one of the most provocative findings in youth mental health research: different types of psychotherapy for adolescent depression work equally well—but not for the reasons we thought. Drawing from the landmark IMPACT trial (the largest UK study of its kind with 465 participants), Professor Goodyer reveals surprising insights that challenge decades of therapeutic orthodoxy. Using cutting-edge network analysis, his team discovered that the key drivers of recovery aren't what therapists predicted—they're fatigue and insomnia, not the psychological symptoms clinicians typically focus on. What You'll Learn The Common Factors Debate: Why CBT, psychoanalytic therapy, and brief psychosocial intervention showed no significant differences in outcomes The Speed of Recovery: Why most young people improved faster than any therapy manual predicted (often in just 6-12 sessions instead of 20-30) Network Science Meets Mental Health: How symptoms influence each other over time—and why this changes everything about diagnosis and treatment The Sleep Connection: Why addressing fatigue and insomnia might be more crucial than we realized for adolescent depression The Role of Time: Why recovery continues for 12 months after therapy ends, with remarkably low relapse rates Why This Matters This isn't just an academic debate. These findings have profound implications for: Clinicians: Rethinking assessment priorities and treatment planning Trainees: Understanding what really drives therapeutic change Researchers: Opening new avenues for investigating mental health interventions Policy makers: Allocating resources more effectively in child and adolescent mental health services Perfect for: Clinical psychologists, psychiatrists, therapists, researchers, students, and anyone interested in what really works in mental health treatment—and why. From the JCPP paper ‘Dynamics of depression symptoms in adolescents during three types of psychotherapy and post-treatment follow-up' Madison Aitken, Sharon A.S. Neufeld, Clement Ma, IMPACT Consortium, Ian M. Goodyer https://doi.org/10.1111/jcpp.14175

Keywords clinical psychology, parenting, adolescence, neurodiversity, identity formation, emotional wellbeing, family dynamics, communication, executive function, teenage brain Summary In this conversation, Dr. Bettina Hohnen, a clinical psychologist specializing in working with young people and their families, shares her insights on the complexities of parenting during adolescence. She discusses her own journey through education, the challenges of neurodiversity, and the importance of understanding the teenage brain. Dr. Hohnen emphasizes the need for effective communication, the significance of identity formation, and the role of respect in parent-teen relationships. She also highlights the importance of self-care for mental health professionals and the need for open discussions about body image with teenagers. Takeaways Dr. Hohnen's journey reflects the diverse paths to success in education. Understanding neurodiversity is crucial for effective parenting. Failure to launch is a common issue for young adults today. Effective communication is key to maintaining relationships with teens. Listening without judgment fosters trust between parents and teens. Repairing relationships after conflicts is essential for emotional safety. Respecting teenagers as individuals is vital for healthy dynamics. Self-awareness in parents can positively influence their children's identity. Discussing body image openly can help prevent issues like eating disorders. Mental health professionals must prioritize their own wellbeing.   Sound bites "Listening is not the same as agreeing." "Behavior is a form of communication." "Surround yourself with young people." Chapters 00:00 Introduction to Dr. Bettina Hohnen and Her Work 02:21 Understanding Neurodiversity and Parenting Challenges 04:41 Navigating the 'Failure to Launch' Phenomenon 08:15 The Impact of Parenting Styles on Child Development 10:09 The Challenges of Parenting During Adolescence 14:04 The Personal Connection to Clinical Practice 15:08 Communication Barriers Between Parents and Teenagers 18:51 Understanding the Adolescent Predicament 23:57 Maintaining Closeness with Teenagers 27:33 Repairing Broken Connections 30:28 Navigating Neurodiversity in Teens 33:35 Supporting Healthy Identity Formation 38:43 Discussing Body Image and Acceptance 40:42 Self-Care for Parents and Professionals  

Keywords clinical psychology, parenting, adolescence, neurodiversity, identity formation, emotional wellbeing, family dynamics, communication, executive function, teenage brain Summary In this conversation, Dr. Bettina Hohnen, a clinical psychologist specializing in working with young people and their families, shares her insights on the complexities of parenting during adolescence. She discusses her own journey through education, the challenges of neurodiversity, and the importance of understanding the teenage brain. Dr. Hohnen emphasizes the need for effective communication, the significance of identity formation, and the role of respect in parent-teen relationships. She also highlights the importance of self-care for mental health professionals and the need for open discussions about body image with teenagers. Takeaways Dr. Hohnen's journey reflects the diverse paths to success in education. Understanding neurodiversity is crucial for effective parenting. Failure to launch is a common issue for young adults today. Effective communication is key to maintaining relationships with teens. Listening without judgment fosters trust between parents and teens. Repairing relationships after conflicts is essential for emotional safety. Respecting teenagers as individuals is vital for healthy dynamics. Self-awareness in parents can positively influence their children's identity. Discussing body image openly can help prevent issues like eating disorders. Mental health professionals must prioritize their own wellbeing.   Sound bites "Listening is not the same as agreeing." "Behavior is a form of communication." "Surround yourself with young people." Chapters 00:00 Introduction to Dr. Bettina Hohnen and Her Work 02:21 Understanding Neurodiversity and Parenting Challenges 04:41 Navigating the 'Failure to Launch' Phenomenon 08:15 The Impact of Parenting Styles on Child Development 10:09 The Challenges of Parenting During Adolescence 14:04 The Personal Connection to Clinical Practice 15:08 Communication Barriers Between Parents and Teenagers 18:51 Understanding the Adolescent Predicament 23:57 Maintaining Closeness with Teenagers 27:33 Repairing Broken Connections 30:28 Navigating Neurodiversity in Teens 33:35 Supporting Healthy Identity Formation 38:43 Discussing Body Image and Acceptance 40:42 Self-Care for Parents and Professionals  

This throwback episode of the Very Clinical Podcast features hosts Kevin and Zach welcoming back Dr. Sully Sullivan to discuss his involvement with 3D Dentists. Sully details the Mastermind program, which focuses on business strategy for successful dentists, advocating for a shift toward comprehensive diagnosis and "fewer, well-planned visits" through the foundational use of full DSLR photography. He then describes the Digital Implant Continuum, highlighting its unique, all-encompassing curriculum that teaches everything from extraction and grafting to guided implant placement and restoration on live patients, emphasizing immediate post-course implementation by having doctors plan and receive guides for their own cases. Some links from the show: 3D Dentists 3D Dentists Mastermind program Join the Very Clinical Facebook group! Join the Very Dental Facebook group using the password "Timmerman," Hornbrook" or "McWethy," "Papa Randy," "Lipscomb" or "Gary!" The Very Dental Podcast network is and will remain free to download. If you'd like to support the shows you love at Very Dental then show a little love to the people that support us! -- Crazy Dental has everything you need from cotton rolls to equipment and everything in between and the best prices you'll find anywhere! If you head over to verydentalpodcast.com/crazy and use coupon code "VERYDENTAL10" you'll get another 10% off your order! Go save yourself some money and support the show all at the same time! -- The Wonderist Agency is basically a one stop shop for marketing your practice and your brand. From logo redesign to a full service marketing plan, the folks at Wonderist have you covered! Go check them out at verydentalpodcast.com/wonderist! -- Enova Illumination makes the very best in loupes and headlights, including their new ergonomic angled prism loupes! They also distribute loupe mounted cameras and even the amazing line of Zumax microscopes! If you want to help out the podcast while upping your magnification and headlight game, you need to head over to verydentalpodcast.com/enova to see their whole line of products! -- CAD-Ray offers the best service on a wide variety of digital scanners, printers, mills and even their very own browser based design software, Clinux! CAD-Ray has been a huge supporter of the Very Dental Podcast Network and I can tell you that you'll get no better service on everything digital dentistry than the folks from CAD-Ray. Go check them out at verydentalpodcast.com/CADRay!

Clinical psychologist and bestselling author Dr. Lisa Miller joins us to reveal the groundbreaking neuroscience that connects spirituality with mental health, purpose, and human flourishing. Drawing from decades of research at Columbia University, she shares how spiritual awareness literally changes the brain — rewiring us for resilience, compassion, and meaning. From the awakened brain to the power of awe, Lisa bridges empirical science with lived spirituality, showing how we are biologically built for connection with something greater than ourselves.www.bioptimizers.com/knowthyselfUse code KNOWTHYSELF for 15% off!https://livemomentous.com and use code KNOWTHYSELF for up to 35% off the best creatine in the gameAndrés Book Recs: https://www.knowthyselfpodcast.com/book-list___________00:00 Intro03:40 What Is the Awakened Brain?07:10 How Spirituality Changes the Brain10:50 Depression as a Doorway to Awakening14:25 The Biology of Faith and Meaning18:05 The Parietal Lobe and the Sense of Oneness22:00 From Egoic Mind to Spiritual Awareness26:15 Dorsal vs. Ventral Attention Networks Explained30:10 How Prayer and Meditation Rewire the Brain34:00 The Neuroscience of Love and Connection38:25 What Happens in the Brain During Awe42:10 Synchronicity and the Science of Guidance46:00 Raising Spiritually Connected Children50:20 Addiction, Recovery, and the Search for Spirit54:35 The Brain as an Antenna for Consciousness59:15 Science Meets Mysticism: Where They Overlap1:03:30 The Future of Mental Health and Spirituality1:07:40 Reawakening the Innate Spiritual Brain1:12:00 Living with Awe, Service, and Gratitude1:16:10 Closing Reflections___________Episode Resources: https://www.lisamillerphd.com/https://www.instagram.com/dr.lisamiller/https://www.instagram.com/andreduqum/https://www.instagram.com/knowthyself/https://www.youtube.com/@knowthyselfpodcasthttps://www.knowthyselfpodcast.com

We have relied on PSA for decades, but what's next in precision screening for prostate cancer? In this episode of BackTable Urology, Dr. Jason Hafron from the Michigan Institute of Urology joins host Dr. Ruchika Talwar to discuss the evolving role of biomarkers and artificial intelligence in prostate cancer screening.---This podcast is supported by:Cleveland Diagnosticshttps://www.isopsa.com/---SYNPOSISTogether, Dr. Hafron and Dr. Talwar examine the ongoing challenges of PSA testing and the promise of next-generation blood-based biomarkers, including 4Kscore and IsoPSA tests. They explore how these advancements are reshaping detection, diagnosis, and risk stratification. The episode also highlights how these tools may improve active surveillance protocols, reduce unnecessary biopsies, and better personalize prostate cancer management for better outcomes.---TIMESTAMPS0:00 - Introduction2:23 - Limitations of PSA10:21 - Limitations of MRI18:08 - Overview of Biomarkers (IsoPSA, 4K, PHI, SelectMDx, MIPS, ExoDx)26:30 - Artificial Intelligence---RESOURCESProstate Cancer Screening With PSA, Kallikrein Panel, and MRI: The ProScreen Randomized Trialhttps://jamanetwork.com/journals/jama/fullarticle/2817323 Using IsoPSA With Prostate Imaging Reporting and Data System Score May Help Refine Biopsy Decision Making in Patients With Elevated PSAhttps://pubmed.ncbi.nlm.nih.gov/36965817/ Clinical validation of IsoPSA, a single parameter, structure-focused assay for improved detection of prostate cancer: A prospective, multicenter studyhttps://pubmed.ncbi.nlm.nih.gov/35840465/

If you've ever felt unsure about what SEO really is — or why your website isn't getting the traffic or clients you expected — this episode is for you.  Daniel pulls back the curtain on the most common misunderstandings therapists have about SEO and shares what's actually working in today's digital landscape. This episode was born out of behind-the-scenes conversations with our Lead SEO Specialist — and the real, recurring questions and roadblocks we see come up with our clients.  Whether it's confusion about how SEO works, frustration over slow results, or the instinct to write your website like a clinical bio, we get it.  We've been there with so many therapists, and we wanted to create an episode that clears the air and sets the record straight.  In this conversation, Daniel unpacks the top things we wish every therapist understood about SEO — so you can stop second-guessing the process and start seeing how strategy, clarity, and patience lead to real growth. The Key Takeaways: Therapists fall under the YMYL (Your Money or Your Life) category, which means Google holds your website to a higher standard. Building E-E-A-T (Experience, Expertise, Authoritativeness, Trustworthiness) is crucial. Your homepage — especially the hero section — should speak directly to your ideal client, not just talk about your practice or credentials. Clinical language often creates distance, unless your audience specifically needs that. Everyday, emotionally resonant language is far more effective. Clients are looking for connection and relief, not a resume. Show them you understand their pain and can help them feel better. Effective SEO isn't a guessing game — it's built on strategy, structure, and research. Following a defined plan gets results. SEO is not the same as running Google Ads. It's a long game, and results build over time — not overnight. Your site might include copy that doesn't sound exactly like you — and that's okay. We're balancing voice with visibility. Nothing in our SEO work is arbitrary. Every tweak and piece of content is intentional and goal-driven. Before you can convert visitors to clients, you have to show up in search results. Visibility comes first. Think of SEO as a marathon, not a sprint. Momentum builds with consistency and time. With the rise of AI and changing search behaviors, SEO today is more like search engineering — blending human psychology and technical strategy. Links mentioned in this episode: 176. Our Top Predictions for SEO in 2025: What Therapists Need to Know What are YMYL websites? How does Google evaluate these? SEO Assessments for Private Practice Schedule a 15-minute Clarity Call This Episode Is Brought To You By   Alma is on a mission to simplify access to high-quality, affordable mental health care by giving providers the tools they need to build thriving in-network private practices. When providers join Alma, they gain access to insurance support, teletherapy software, client referrals, automated billing and scheduling tools, and a vibrant community of clinicians who come together for education, training, and events. Learn more about building a thriving private practice with Alma at helloalma.com/elevation. About Daniel Fava Daniel Fava is the owner and founder of  Private Practice Elevation, a website and SEO agency focused on helping private practice owners create websites that increase their online visibility and attract more clients. Private Practice Elevation offers web design services, SEO (search engine optimization), and WordPress support to help private practice owners grow their businesses through online marketing.  Daniel lives in Atlanta, GA with his wife Liz, and two energetic boys. When he's not working he enjoys hiking by the river, watching hockey, and enjoying a dram of bourbon.  

Clinical psychologist and parenting expert Dr. John Duffy joins Wendy Snyder (in for Bob Sirott) to talk about the deaths of Illinois gubernatorial candidate Darren Bailey’s son and his family and how this could impact his ten-year-old grandson. He explains the best way to talk to children about death and how children in past generations […]

Summary In this episode of the Future of Dermatology podcast, guest speaker Dr. Donna Culton, delves into the intricate science of skin diseases, focusing on the pathophysiology of conditions like pemphigoid. The discussion covers the roles of B cells, autoantibodies, and various cellular players in inflammation, as well as the mediators that contribute to symptoms like itch. The episode emphasizes the complexity of these diseases and the potential for new therapeutic targets, while also highlighting the challenges in conducting clinical trials for affected populations. Takeaways - Dr. Culton emphasizes the importance of understanding B cells in skin diseases. - Pemphigus and pemphigoid have distinct clinical presentations and treatments. - Autoantibodies play a crucial role in the pathophysiology of pemphigoid. - Mast cells and eosinophils are key players in the inflammatory response. - Cytokines like IL-4 and IL-5 are critical for B cell activation and eosinophil recruitment. - The itch associated with pemphigoid is complex and not solely due to histamine. - Clinical trials for skin diseases face unique challenges due to patient comorbidities. - Understanding the mediators of degradation can inform treatment strategies. - The complexity of skin diseases allows for multiple therapeutic targets. - This podcast serves as an educational resource for understanding dermatological science. Chapters 00:00 - Introduction to Dermatology and B Cells 02:51 - Understanding Pemphigus and Pemphigoid 05:25 - The Role of Autoantibodies in Skin Diseases 08:20 - Key Cellular Players in Inflammation 10:53 - Mediators of Inflammation and Itch 13:57 - Pathophysiology and Future Therapies

Today's episode is one I've really been looking forward to because we're diving into something that's transforming the way we think about mental health treatment: low-dose ketamine therapy. My guest, Dr. Sharon Niv, is the co-founder of Joyous, a public benefit company helping make this kind of care more accessible and affordable than ever before. Sharon brings a fascinating background in cognitive psychology, meditation, and technology, and she's helping bridge the gap between neuroscience and therapy in a way that's incredibly gentle, safe, and empowering for both clients and clinicians. We'll talk about what makes psycholytic, or low-dose, ketamine different from traditional psychedelic experiences, how it can enhance the therapeutic process, and how you, as a therapist, can get trained to integrate it into your own work. This is one of those conversations that opens your mind to what's possible in therapy, so let's jump in. Resources Mentioned In This Episode Use the promo code "GORDON" to get 2 months of Therapy Notes free Consulting with Gordon The PsychCraft Network Profit First for Therapists Workbook Meet Sharon Niv, Ph.D. Dr. Sharon Niv is a cognitive psychologist and co-founder of Joyous Team, a Public Benefit Corporation dedicated to making evidence-based mental health treatments accessible and affordable. Her work bridges the worlds of neuroscience, technology, and therapy with a focus on how scalable, data-driven approaches can enhance emotional well-being. Dr. Niv earned her Ph.D. in Brain and Cognitive Science from the University of Southern California, where she conducted research on EEG biomarkers, neurofeedback, and the neural underpinnings of mood and behavior. She also holds a B.A. in Molecular and Cellular Biology from UC Berkeley and an M.A. in Clinical and Cognitive Psychology from USC. Before founding Joyous, Sharon worked on developing virtual-reality interventions for chronic pain and neurofeedback programs designed to help people improve emotional regulation and resilience. A long-time meditation practitioner, she combines scientific rigor with a deep understanding of mindfulness and experiential learning. Through Joyous, Sharon and her team are pioneering low-dose (psycholytic) ketamine therapy, creating safer, more sustainable pathways for individuals and therapists to experience healing and insight. Her mission is to empower both clinicians and clients with practical tools that promote neuroplasticity, compassion, and mental clarity. The Power of Therapy + Joyous Joyous Substack LinkedIn

Today we're thrilled to get to know Travis Zack, Chief Medical Officer of OpenEvidence. OpenEvidence is the world's leading medical information platform and the fastest growing applications for physicians in history. Over 40% of US clinicians leverage OpenEvidence for evidence based practice support that is directly embedded into their workflows.Through an array of strategic content partnerships (including the American Medical Association, The New England Journal of Medicine, The Journal of the American Medical Association, and all eleven JAMA specialty journals—such as JAMA Oncology and JAMA Neurology) OpenEvidence gives clinicians the power to search once, skip the scavenger hunt, and surface the science in seconds. Most recently, OpenEvidence has raised $200M in its Series C from Top Investors like Sequoia, GV Thrive, Kleiner Perkins and others!In this episode, we discuss how OpenEvidence is transforming access to medical evidence, the company's rapid growth and adoption by clinicians, its business model and journal partnerships, and the future roadmap for AI-powered clinical decision support.

“Leadership isn't about control anymore — it's about connection.”What if everything you thought about leadership was based on outdated assumptions?In this special episode from the 2025 HAOP Forum Series – part of our Design-Thinking Program for Health System, Clinical, and Nursing Leaders – I'm joined by Dana Greenberg and Scott Taylor of Babson College to rethink what leadership must look like in today's complex world.Together, they break down:• Why leadership must shift from individualism to relational models• How entrepreneurial mindsets unlock innovation in healthcare and beyond• Why identity, empathy, and care are performance drivers—not distractions• What's keeping people in the wrong roles—and how to fix it• Why younger generations will leave if institutions don't evolveThis isn't theory—it's a roadmap for how leaders must show up today.---------------------------------------------------------------------------------------------------------------------------

“Hard things are worth doing.”In this powerful episode of the Special 2025 Healthcare in the Age of Personalization Series, pediatric neurosurgeon Dr. Amanda Saratsis shares why purpose, grit, and leadership are essential to reclaiming dignity in healthcare — especially for our most vulnerable patients.Here's what Dr. Saratsis reveals:• Why surgical precision and musical discipline go hand-in-hand• How physician burnout is tied to standardized systems that dehumanize care• Why pediatric cancer is rising — and what needs to change fast• How technology and personalization are reshaping trust at the bedsideIt's an urgent call for healthcare leaders to lead with empathy, act faster, and never forget who they're here to serve.---------------------------------------------------------------------------------------------------------------------------

"Everyone is in the healthcare business now — whether they realize it or not."In this compelling episode of the Personalization Outbreak podcast, Honor Technology CEO Seth Sternberg reveals why caregiving is one of the most urgent — and overlooked — challenges facing the healthcare system and the workforce.With 1 in 5 employees silently caring for aging parents, companies are losing productivity, trust, and talent without even realizing it.And yet, most leaders don't see caregiving as a business issue — until it's too late.Here's what Seth breaks down:• Why 95% of older adults live at home — and why healthcare must follow them there• How AI is unlocking scalable, human-centered care• What employers can do right now to support working caregivers• Why home care is the future — and the workplace must adapt---------------------------------------------------------------------------------------------------------------------------

What's really behind the burnout crisis in nursing leadership?In this powerful new episode of the Personalization Outbreak Podcast, part of our special 2025 Healthcare in the Age of Personalization (HAOP) Forum Series, Glenn Llopis sits down with Lori Gunther (CEO, Sunova Associates) and Nancy Travis (Executive Nurse Consultant) for an honest conversation about:✅ Why 24/7 accountability is breaking nurse leaders✅ The silent toll of "monkey in the middle" leadership✅ How systemic change and personalized leadership must go hand in hand✅ What C-suite leaders can learn from nurses—and why they must listen now

"Purpose isn't soft. It's your most powerful energy source."In this eye-opening episode of the special HAOP Podcast Series, strategist and CEO Rob Craven explains why purpose is no longer a spiritual concept—it's a strategic advantage.From scaling companies to transforming leadership culture, Rob shares how tapping into personal purpose can unlock exponential energy, innovation, and growth.This episode challenges outdated models of leadership and exposes what's keeping organizations stuck in “Capitalism 2.0.”Key insights include:• Why your toughest life experiences often reveal your true purpose• How unconscious leaders drain energy from their teams• Why personalization—not standardization—is the key to future success• What it really takes to scale impact and build movements, not just companies---------------------------------------------------------------------------------------------------------------------------

Hosted in partnership with Chiesi, Dr. Joyce Teng and Dr. Emily Gorell share their real-world clinical experiences, highlighting how birch triterpenes may work to accelerate wound healing, reduce inflammation, and potentially improve quality of life for patients living with dystrophic and junctional epidermolysis bullosa (EB). The program also touches on the importance of wound preparation, combinatorial approaches to therapy, and holistic care approaches for these patients.This is an audio version of a webinar that includes slides. To view the slides referenced in this program, please click here.A complete list of guests' disclosures can also be found here.This webinar is being hosted by PeDRA and sponsored by Chiesi. PeDRA will evaluate content for suitability for its audience, but is not responsible for the creation of content, selection of speakers, or delivery of presentations. For a complete list of presenter disclosures, please click on the presenters' photographs.

Danny Bega, MD, of Northwestern Medicine Neurology, joins Will Meador, MD, to discuss a major breakthrough in Huntington's disease — a gene therapy that has shown the first evidence of slowing disease progression. Dr. Bega talks about how the RESET-HD trial is reshaping treatment possibilities and what physicians should watch for as this therapy advances.

Discover the future of anti-aging skincare with plant-powered growth factors that outperform retinol without irritation. In this episode, Facially Conscious co-hosts Trina Renea and Rebecca Gadberry sit down with Tony Abboud, Chief Commercial Officer of Core Biogenesis, to explore breakthrough oleosome technology. Learn how Peauvita™ and Peauforia™ use nature's delivery system to penetrate deeper into the skin, delivering clinically proven results in just 14 days—faster than traditional retinol. Clinical studies show superior wrinkle reduction, improved smoothness, and enhanced brightness without redness or flaking. Rebecca Gadberry shares her personal 10-day transformation, while the team discusses why growth factors are ranking as a top skincare trend for 2026. If you're ready to future-proof your skin with sustainable, science-backed ingredients, this conversation is essential listening.

In this episode of our series on APAC countries' EMR implementation, Franklin Vibar, CIO of Asian Hospital and Medical Center in the Philippines, talks about how the hospital guided physicians and staff through the implementation of an EMR system and achieved 95% adoption. 

*This Episode is In Partnership with Wild Nutrition*In this episode I'm chatting to Isabelle Nunn. Isabelle is a registered clinical nutritional therapist with a Master's in Pharmacy and is also the Head of Nutrition at Wild Nutrition which is one of my most trusted supplement brands.During the episode we chat about general health, particularly in peri-menopause and the things that we can do to help ourselves feel stronger and better. We also discuss the way that Wild Nutrition work (you have a free talk with a nutritionist so that you can work out the supplements that you might need) and what makes their supplements stand apart.Finally we delve into the world of collagen and hear from two of the Outspoken Beauty Panellists who have been trialling the Wild Nutrition marine collagen and the positive results they have seen.I really hope you enjoy this incredibly informative episode and that it helps you get your head round the often confusing world of supplements.

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are distressed by the continuing government shutdown, first locally acquired chikungunya virus infection, President Trump's suggestion for removing aluminum from vaccines, H5N1 isolation from backyard birds and turkey farms, and the suggestion of establishing an alternative to the CDC's MMWR and asymptomatic measles infections before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the quarantining in the US due to measles, access to anti-influenza antiviral, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, if colchicine is effective for long COVID, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode New York health officials confirm state's first locally acquired case of chikungunya virus (AP News) Trump Rattles Vaccine Experts Over Aluminum (NY Times) Aluminum-Adsorbed Vaccines and Chronic Diseases in Childhood (Annals of Internal Medicine) Three large turkey farms in Minnesota hit with H5N1 avian flu (CIDRAP) Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service) Jeffrey Lee McLean (California.No) California mpox cases raise concerns. But health officials say the risk remains low (AP News) ‘Alternative' to CDC's Flagship Journal in the Works (MEDPAGE TODAY) Measles without rash during acute febrile illness surveillance in Tanzania, 2023-2024 (CID) Frustration grows amid measles outbreak quarantines across several states (NBC News) More Than 100 Cases of Measles Reported in Utah and Arizona (NY Times) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Tracking Measles Cases in the U.S. (Johns Hopkins) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine recommendations from NYP (jpg) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) ACIP Recommendations Summary (CDC: Influenza) American Academy of Pediatrics Flu and Children (CDC: Influenza (flu)) Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season(FDA) Roche to sell flu pill for $50 to cash-paying US patients (Reuters) RSV: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Evidence to Recommendations Framework (EtR): RSV Vaccination in Adults Aged 50–59 years (CDC: National Center for Immunization and Respiratory Diseases) Efficacy and safety of respiratory syncytial virus vaccines (Cochrane Library) Estimated Vaccine Effectiveness for Respiratory Syncytial Virus–Related Acute Respiratory Illness in Older Adults (CID) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Effectiveness of Colchicine for the Treatment of Long COVID(JAMA Internal Medicine) Reaching out to US house representative Letters read on TWiV 1264 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

Saturday, October 25, 2025. Week 43.   Time to advocate, ELF on the Hill, support available, apply now: https://www.linkedin.com/posts/everylifeorg_were-excited-to-join-everyone-on-capitol-activity-7384625926333943808-mO1U/   PUBMED at 47, and low. Clinical research! https://pubmed.ncbi.nlm.nih.gov/?term=syngap1&filter=years.2025-2025&sort=date   - CHOP EEG ProMMiS ​​https://www.neurology.org/doi/10.1212/WNL.0000000000214148?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed - COMMUNICATION #ORCA https://acamh.onlinelibrary.wiley.com/doi/full/10.1111/jcpp.70063   Doing surveys gets us into papers like ORCA, helps us raise awareness of SRD.  This one on AI is really interesting: https://redcap.tch.harvard.edu/redcap_edc/surveys/?s=YFHYH7T7LTPAL44X   Newsletter #47 https://mailchi.mp/curesyngap1.org/unlock-their-tomorrow-issue47    IPM on SRD AAV https://www.insideprecisionmedicine.com/topics/precision-medicine/gene-therapy-reverses-syngap1-brain-disorder-symptoms-in-mice/   NYT Take on #Autism is very good, thank you Azeen Ghorayshi Split the Autism Spectrum: https://www.nytimes.com/2025/10/01/health/autism-spectrum-neurodiversity-kennedy.html?unlocked_article_code=1.q08.NXEA.fg5ulHeTHUeJ&smid=url-share quotes Jackie K, explores argument for Profound & Severe Autism as a category.    Our own Jackie Kancir has a great substack, listen to it in her voice here: https://jkancir.substack.com/p/autism-is-not-my-daughter-nor-her   Tylenol: https://www.nytimes.com/video/science/100000010414944/trump-pushes-unproven-link-between-tylenol-and-autism.html   Sign up for Citizen Health: https://www.citizen.health/partners/srf   CURE SYNGAP1 Conference 2025 Atlanta: https://curesyngap1.org/events/conferences/cure-syngap1-conference-2025-hosted-by-srf/   USE YOUR ICD-10 F78.A1 #S10e185 https://www.youtube.com/watch?v=dale0NbxDpU   SOCIALS 4,417 LinkedIn.  https://www.linkedin.com/company/curesyngap1/  1,470 YouTube.  https://www.youtube.com/@CureSYNGAP1    11k Twitter https://twitter.com/cureSYNGAP1  45k Insta https://www.instagram.com/curesyngap1/    Episode 187 of #Syngap10 #CureSYNGAP1

John Murray, Ian Dennis & Ali Bruce-Ball talk football, travel & language. They discuss a high-scoring week in the UEFA Champions League, what jobs they would do if they weren't commentators & the unintended pub crawl just gets longer! Suggestions welcome for our Great Glossary of Football Commentary and unintended pub names from football commentary - WhatsApp voicenotes to 08000 289 369 & emails to TCV@bbc.co.uk00:40 Ian gets destroyed by Herr Chapman 04:25 Champions League reflections 11:10 5 Live commentaries this weekend 13:00 What job would they do if not commentary? 17:20 Unintended pub names from football commentary 22:10 Top vs bottom in Clash of the Commentators 34:40 Great Glossary of Football CommentaryBBC Sounds / 5 Live Premier League commentaries: Sat 1500 Chelsea v Sunderland, Sat 1500 Newcastle v Fulham on Sports Extra, Sat 1730 Man Utd v Brighton, Sun 1400 Arsenal v Crystal Palace, Sun 1400 Aston Villa v Man City on Sports Extra, Sun 1400 Bournemouth v Nottingham Forest on BBC Sport website & app, Sun 1400 Wolves v Burnley on BBC Sport website & app, Sun 1630 Everton v Tottenham.Glossary so far:DIVISION ONE Bosman, Cruyff Turn, Giving the goalkeeper the eyes, Hibs it, The Maradona, Onion bag, Panenka, Rabona, Tiki-taka, Where the kookaburra sleeps, Where the owl sleeps, Where the spiders sleep.DIVISION TWO Ball stays hit, Coat is on a shoogly peg, Daisycutter, Has that in his locker, Howler, One for the cameras, Played us off the park, Purple patch, Root and branch review, Row Z, Stramash, Taking one for the team, That's great… (football), Thunderous strike.UNSORTED 2-0 is a dangerous score, After you Claude, All-Premier League affair, Aplomb, Bag/box of tricks, Brace, Brandished, Bread and butter, Breaking the deadlock, Bundled over the line, Champions elect / champions apparent, Clinical finish, Commentator's curse, Coupon buster, Cultured/Educated left foot, Denied by the woodwork, Draught excluder, Elimination line, Fellow countryman, Foot race, Formerly of this parish, Fox in the box, Free hit, Goalkeepers' Union, Goalmouth scramble, Good touch for a big man, Honeymoon Period, In and around, In the shop window, Keeping ball under their spell, Keystone Cops defending, Languishing, Loitering with intent, Marching orders, Nestle in the bottom corner, Numbered derbies, Nutmeg, Opposite number, Park the bus, PK for penalty-kick, Postage stamp, Put it in the mixer, Put their laces through it, Rasping shot, Red wine not white wine, Relegation six-pointer, Rooted at the bottom, Route One, Roy of the Rovers stuff, Sending the goalkeeper the wrong way, Shooting boots, Sleeping giants, Slide rule pass, Small matter of, Spiders web, Stayed hit, Steepling, Stinging the palms, Stonewall penalty, Straight off the training ground, Taking one for the team, Team that likes to play football, Throw their cap on it, Thruppenny bit head / 50p head, Towering header, Two good feet, Turning into a basketball match, Turning into a cricket score, Usher/Shepherd the ball out of play, Walking a disciplinary tightrope, Wand of a left foot, We've got a cup tie on our hands, Winger in their pocket, Wrap foot around it, Your De Bruynes, your Gundogans etc.