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Ali's guest today is Jess Mayhugh, a writer and editor who spent nearly a decade trying to have a baby before the arrival of her son, Cole. Jess's journey includes multiple miscarriages, rounds of IVF, several reproductive surgeries, and the unimaginable heartbreak of losing her newborn daughter, Lucy. On this episode, Jess opens up about navigating it all. It's a story of profound loss, incredible resilience, and massive love. IG: @jessmayhugh EPISODE SPONSORS: THE WORK OF ART BOOK SERIESAli's Children's Book Series about IVF, IUI and Family Building Through Assisted Reproductive Technology https://www.infertileafgroup.com/booksThe latest book in the Work of ART series, “You Are a Work of ART," is for every kiddo born through ART -- and the people who love them.Stay tuned for Petri Dish Princess, book #4, coming this fall!EXTEND FERTILITYExtend Fertility is a leading fertility clinic helping people take control of their reproductive futures through egg freezing, embryo freezing, IVF, and more. With a focus on making fertility care more accessible, empowering, and personalized, Extend combines cutting-edge science with compassionate care to help patients understand their options and make informed decisions about if, when, and how they want to build a family.For more, go to extendfertility.comPHERDALIG: @pherdal_sciencePherDal is the world's first and only FDA-cleared, sterile, at-home insemination kit designed to help people build their families in the comfort of home. Created by parents who've been there, PherDal is safe, simple, and affordable—putting more options in your hands as you grow your family. Explore at PherDal.com.Go to PherDal.com today and use code INFERTILEAF for $10 off.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
>p>Broadcast from KSQD, Santa Cruz on 7-30-2026: A type of coffee brewed from beans that have been altered by passage through the digestive track of civet cats is a delicacy in Southeast Asia. A Scientific Reports paper using gas chromatography analyzed Kopi Luwak (civet-processed coffee beans) versus fresh-picked beans, finding elevated caprylic and capric acids that carry the characteristic flavor notes found in dairy products. Dr. Manuel Esteller sampled and tested the blood, saliva, urine, and stool of the oldest human Maria Branyas Morera, who died last year at 117. Despite exceptionally short telomeres, she carried anti-inflammatory genetic variants seen in long-lived dogs, worms, and flies, and had unusually high Bifidobacterium levels—likely boosted by her three-daily-servings-of-yogurt habit. Dr. Dawn defends sunscreen use against Environmental Working Group scare campaigns, noting that concerns about absorption of sunscreen ingredients into blood remain theoretical while sunburn's melanoma link is well-established. She argues that a badly sunburned toddler starts a clock that can produce melanoma by the late teens. The FDA advisory committee is reviewing certain short amino acid chains popularly known as "peptides" for potential compounding-pharmacy production, covering proposed to treat ulcerative colitis, wound healing, insomnia, insulin resistance, migraines, and osteoporosis. Dr. Dawn flags that five to seven committee members have industry conflicts of interest, but argues that even flawed approval is preferable to the current gray market, where analysis shows vials contain only 4-28% of labeled content along with endotoxin and toluene contamination. She proposes surveillance tracking of prescribed peptides to catch adverse effects early, citing a foreign melanocortin nasal spray tanning product that caused rare nasal melanomas as a cautionary example. Utah State biochemists working with the Cas12a2 CRISPR enzyme discovered that instead of behaving as a precise gene-editor like Cas9, it goes into an indiscriminate DNA-shredding mode after recognizing its target RNA. By programming it to recognize RNA sequences uniquely activated in cancer cells (embryonic-development genes that shouldn't be running in adults), researchers destroyed only the cancer cells in tissue culture, potentially offering a way to eliminate small metastases without healthy tissue toxicity. Cancer patients who received a COVID-19 mRNA vaccine within 100 days of starting immune checkpoint inhibitor therapy showed dramatically improved outcomes, with median survival in advanced lung cancer rising from 20 to 37 months. Non-mRNA vaccines (flu, pneumonia) showed no such benefit. Lab work suggests the mRNA triggers type-1 interferon release that activates tumor-infiltrating immune cells and drives them to lymph nodes to train other immune cells against the tumor. Researchers redesigned a CD40 agonist antibody to bind multiple receptors simultaneously by clustering with a second antibody, stretching the cell surface and triggering a powerful immune response. In a 12-patient trial, injecting one tumor caused all tumors to shrink in six patients and produced complete remission in two—including a melanoma patient with dozens of leg tumors and a metastatic breast cancer patient whose lung and liver tumors resolved after skin injection. Two small trials of CAR natural killer cells—engineered like CAR T-cells but derived from donor umbilical cord blood and thus potentially available off-the-shelf—showed remarkable results in autoimmune disease. All 27 systemic lupus patients targeting the CD19 protein on autoantibody-producing cells showed improvement, with some remaining in remission at nearly two years. A single Shanghai patient with systemic sclerosis showed restoration of normal skin and blood vessel structure. A paradox has emerged in advanced prostate cancer: while blocking testosterone halts early tumor growth, cancer cells eventually adapt to low-androgen conditions such that flooding tissues with testosterone in advanced disease can actually halt tumor progression by triggering cellular redifferentiation. Separately, Dr. Dawn reviews conflicting evidence on Parkinson's risk from androgen deprivation therapy, singling out enzalutamide (Xtandi) as the most concerning drug due to blood-brain barrier penetration, and recommending darolutamide as the safest alternative with matching prostate efficacy but minimal CNS entry.
Further Reading:‘Not standard' for Taylor Farms to ask White House to delay cyclospora recall, ex-FDA head says - LINKMassachusetts 1st Congressional District Primary Debate: Neal vs. Whalen - LINKElon Musk's AI company is suing to block a new Minnesota law against certain AI apps - LINKHamas says it will disarm if Israel halts strikes and withdraws from Gaza, but obstacles remain - LINK Beginning Music: Glenn Gould - Goldberg Variation #5Ending Music: Electronic - Getting Away With it (Instrumental)Remember to Register to vote! Mass Residents should go to: https://www.sec.state.ma.us/ele/For more Civil Politics visit our website, civilpoliticsradio.com!If you want to get alerted to new episodes on social media, follow our Bluesky: @CivilPoliticsRadio.comDon't miss another episode - subscribe to our podcast (iTunes, Google Play, Spotify, and more!)This podcast is a member of the Planetside Podcast Network. Visit PlanetsidePodcasts.com to find other Planetside Productions!
President Donald Trump is defending the controversial Department of Justice "anti-weaponization fund" as his pick for permanent Attorney General hangs in the balance. An estimated 60,000 migrants rush the border between Morocco and Spain. New York becomes the latest state to take the prediction market Kalshi to court. Anthropic admits its AI models also went rogue and hacked outside systems. And certain peptides get one step closer to FDA approval. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Tarabuster Thursday with Tara Devlin. July 30, 2026
Send Zorba a message!Zorba shares his thoughts on the recent Cyclosporiasis outbreak, and how staffing cuts implemented by The Department of Government Efficiency (DOGE) have made the outbreak worse.Support the showProduction, edit, and music by Karl ChristensonSend your question to Dr. Zorba (he loves to help!):Phone: 608-492-9292 (call anytime)Email: askdoctorzorba@gmail.comWeb: www.doctorzorba.orgStay well!
Clinical Trial Podcast | Conversations with Clinical Research Experts
Statistics influence almost every major decision in a clinical trial. In this episode, Roseann White, a retired biostatistician with more than 30 years of experience, joins the Clinical Trial Podcast to make biostatistics practical for clinical research professionals. Roseann explains what statistical significance really means, why clinical meaning matters, how to think about superiority and non-inferiority, and why sensitivity and specificity can confuse even experienced teams. We also discuss endpoint selection, statistical analysis plans, financial constraints, FDA disagreements, and the questions non-statisticians should ask earlier in the trial design process. This is a practical conversation for anyone involved in designing, conducting, analyzing, or interpreting clinical trials.
Core Skills for Biotech Drug Development Hello, this is Hall T. Martin with the Startup Funding Espresso -- your daily shot of startup funding and investing. Investors looking to invest in a biotech drug startup should diligence the team for key skills. Here are the key skills needed for biotech drug development: Knowledge of how to drug a target. This means identifying a molecule, often a protein, that is associated with the disease to be treated and could be treated by a drug. Ability to elucidate the mechanism of action. This is the process by which a drug functions to produce a pharmacological effect. Demonstrate safety and efficacy. This shows the therapeutic works and is non-toxic. Ability to design clinical trials to show safety and efficacy. This requires the ability to pick the right therapeutic indication and the appropriate patient population. Finally, understand the regulatory requirements for approval. This means identifying the right FDA path and the steps required to reach approval. Consider these skills in a founder before investing in a biotech drug startup. Thank you for joining us for the Startup Funding Espresso where we help startups and investors connect for funding. Let's go startup something today. _______________________________________________________ For more episodes from Investor Connect, please visit the site at: http://investorconnect.org Check out our other podcasts here: https://investorconnect.org/ For Investors check out: https://tencapital.group/investor-landing/ For Startups check out: https://tencapital.group/company-landing/ For eGuides check out: https://tencapital.group/education/ For upcoming Events, check out https://tencapital.group/events/ For Feedback please contact info@tencapital.group Please follow, share, and leave a review. Music courtesy of Bensound.
This week, Emily Bazelon, John Dickerson, and David Plotz discuss the expanding Iran war and what it means for Trump that news of U.S. missile shortages is leaking from the inside, the blend of conspiracy theory and Rand Paul's personal umbrage that drove the show trial of a Senate hearing with Dr. Anthony Fauci, and various developments that brought medication abortion and FDA restrictions back to the news this week.Here are this week's chatters: Emily: Julia Lurie for Mother Jones: Me, Myself, and IUDs John: Space Daily: Astronauts returning from six-month missions describe a persistent 'observer' sensation — the feeling of watching their own lives from a half-step outside the frame, weeks after they're back on the ground David: Jill Lawless for The Associated Press: Glen Hansard, Irish musician who won Oscar for ‘Once,' dies in motorcycle crash; Once (2007) Trailer HD | Glen Hansard | Markéta Irglová (YouTube); RTÉ News on YouTube: 'Fairytale of New York' played at Shane MacGowan's funeral; City Cast: Your City Could Be Better (podcast); Eli Sabin for New Haven Listener chatter from Craig Kujawa in Washington, D.C.: Barbershop Harmony Society: History Made: GQ Wins World Championship; Barbershop Harmony Society: GQ - Mothers & Daughters (Maddie Zahm cover) • 2026 BHS International Quartet Champions (YouTube) For this week's Slate Plus bonus episode, Emily, John, and David discuss the rise of the Democratic Socialists of America with guest Grace Mausser, Co-Chair of the New York City DSA. They talk about its European-style organizing model, its uneasy alliance with the Democratic Party, the primacy of canvassing and volunteering, and the art of compromise. In the latest Gabfest Reads, John Dickerson interviews Maggie Haberman and Jonathan Swan about their new book Regime Change: Inside the Imperial Presidency of Donald Trump. Drawing on extensive reporting from inside the White House, they explore how Trump's second term differs radically from his first, from his decision-making process to the people surrounding him and his relationship with power, money, and the presidency itself. Email your chatters, questions, and comments to gabfest@slate.com. (Messages may be referenced by name unless the writer stipulates otherwise.) Podcast production by Nina Porzucki Research by Emily DittoYou can find the full Political Gabfest show pages here. Want more Political Gabfest? Join Slate Plus to unlock weekly bonus episodes. Plus, you'll access ad-free listening across all your favorite Slate podcasts. You can subscribe directly from the Political Gabfest show page on Apple Podcasts and Spotify. Or visit slate.com/gabfestplus to get access wherever you listen. Find out more about David Plotz's monthly tours of Ft. DeRussy, the secret Civil War fort hidden in Rock Creek Park. Follow@SlateGabfest on X / https://twitter.com/SlateGabfestSlate Political Gabfest on Facebook / https://www.facebook.com/Gabfest/Need to set up your Slate Plus feed? If you subscribed through Slate.com, check out our FAQ at slate.com/podcastfaqs for easy instructions. Members subscribed via Apple Podcasts get automatic access—no setup required. Hosted on Acast. See acast.com/privacy for more information.
On the heels of the success of GLP-1s like Ozempic, other peptide treatments are flooding the marketplace—and advertising spaces. But even as the Trump administration's FDA discusses approving more treatments and the businesses selling them proliferate, many peptides are sitting in a legal and medical gray area. So how real - and safe - is this peptide hype?Guest: Kate Knibbs, senior writer at WIRED.Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.Podcast production by Rob Gunther, Evan Campbell, Madeline Thames-Ducharme and Patrick Fort.Paige Osburn is the senior supervising producer of What Next and What Next TBD. Hosted on Acast. See acast.com/privacy for more information.
This week, Emily Bazelon, John Dickerson, and David Plotz discuss the expanding Iran war and what it means for Trump that news of U.S. missile shortages is leaking from the inside, the blend of conspiracy theory and Rand Paul's personal umbrage that drove the show trial of a Senate hearing with Dr. Anthony Fauci, and various developments that brought medication abortion and FDA restrictions back to the news this week.Here are this week's chatters: Emily: Julia Lurie for Mother Jones: Me, Myself, and IUDs John: Space Daily: Astronauts returning from six-month missions describe a persistent 'observer' sensation — the feeling of watching their own lives from a half-step outside the frame, weeks after they're back on the ground David: Jill Lawless for The Associated Press: Glen Hansard, Irish musician who won Oscar for ‘Once,' dies in motorcycle crash; Once (2007) Trailer HD | Glen Hansard | Markéta Irglová (YouTube); RTÉ News on YouTube: 'Fairytale of New York' played at Shane MacGowan's funeral; City Cast: Your City Could Be Better (podcast); Eli Sabin for New Haven Listener chatter from Craig Kujawa in Washington, D.C.: Barbershop Harmony Society: History Made: GQ Wins World Championship; Barbershop Harmony Society: GQ - Mothers & Daughters (Maddie Zahm cover) • 2026 BHS International Quartet Champions (YouTube) For this week's Slate Plus bonus episode, Emily, John, and David discuss the rise of the Democratic Socialists of America with guest Grace Mausser, Co-Chair of the New York City DSA. They talk about its European-style organizing model, its uneasy alliance with the Democratic Party, the primacy of canvassing and volunteering, and the art of compromise. In the latest Gabfest Reads, John Dickerson interviews Maggie Haberman and Jonathan Swan about their new book Regime Change: Inside the Imperial Presidency of Donald Trump. Drawing on extensive reporting from inside the White House, they explore how Trump's second term differs radically from his first, from his decision-making process to the people surrounding him and his relationship with power, money, and the presidency itself. Email your chatters, questions, and comments to gabfest@slate.com. (Messages may be referenced by name unless the writer stipulates otherwise.) Podcast production by Nina Porzucki Research by Emily DittoYou can find the full Political Gabfest show pages here. Want more Political Gabfest? Join Slate Plus to unlock weekly bonus episodes. Plus, you'll access ad-free listening across all your favorite Slate podcasts. You can subscribe directly from the Political Gabfest show page on Apple Podcasts and Spotify. Or visit slate.com/gabfestplus to get access wherever you listen. Find out more about David Plotz's monthly tours of Ft. DeRussy, the secret Civil War fort hidden in Rock Creek Park. Follow@SlateGabfest on X / https://twitter.com/SlateGabfestSlate Political Gabfest on Facebook / https://www.facebook.com/Gabfest/ Hosted on Acast. See acast.com/privacy for more information.
Tickets for our live show in New York are on sale now! Get yours here. Peptides are a huge part of the wellness craze that's sweeping social media. Demand for restricted peptides has fueled an online gray market for injections promising youth, beauty and strength. Businesses are racing—and taking risks—to get in on the craze. WSJ's Sara Ashley O'Brien explores the burgeoning peptide market and how a recent FDA hearing could signal things are only just getting started. Jessica Mendoza hosts. Further Listening: - Trillion Dollar Shot - The FDA Boss on the Agency's MAHA Makeover Sign up for WSJ's free What's News newsletter. Learn more about your ad choices. Visit megaphone.fm/adchoices
On the heels of the success of GLP-1s like Ozempic, other peptide treatments are flooding the marketplace—and advertising spaces. But even as the Trump administration's FDA discusses approving more treatments and the businesses selling them proliferate, many peptides are sitting in a legal and medical gray area. So how real - and safe - is this peptide hype?Guest: Kate Knibbs, senior writer at WIRED.Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.Podcast production by Rob Gunther, Evan Campbell, Madeline Thames-Ducharme and Patrick Fort.Paige Osburn is the senior supervising producer of What Next and What Next TBD. Hosted on Acast. See acast.com/privacy for more information.
This week, Jasmin and Mariann dig into a wave of encouraging news for the plant-based movement alongside a sobering look at threats to wildlife protections. They cover new data showing plant-based sales climbing across Europe as prices and taste improve, the FDA’s struggle to define “ultra-processed foods” (and its decision not to ban them), a lawsuit challenging the Trump administration’s rollback…
This week, Emily Bazelon, John Dickerson, and David Plotz discuss the expanding Iran war and what it means for Trump that news of U.S. missile shortages is leaking from the inside, the blend of conspiracy theory and Rand Paul's personal umbrage that drove the show trial of a Senate hearing with Dr. Anthony Fauci, and various developments that brought medication abortion and FDA restrictions back to the news this week.Here are this week's chatters: Emily: Julia Lurie for Mother Jones: Me, Myself, and IUDs John: Space Daily: Astronauts returning from six-month missions describe a persistent 'observer' sensation — the feeling of watching their own lives from a half-step outside the frame, weeks after they're back on the ground David: Jill Lawless for The Associated Press: Glen Hansard, Irish musician who won Oscar for ‘Once,' dies in motorcycle crash; Once (2007) Trailer HD | Glen Hansard | Markéta Irglová (YouTube); RTÉ News on YouTube: 'Fairytale of New York' played at Shane MacGowan's funeral; City Cast: Your City Could Be Better (podcast); Eli Sabin for New Haven Listener chatter from Craig Kujawa in Washington, D.C.: Barbershop Harmony Society: History Made: GQ Wins World Championship; Barbershop Harmony Society: GQ - Mothers & Daughters (Maddie Zahm cover) • 2026 BHS International Quartet Champions (YouTube) For this week's Slate Plus bonus episode, Emily, John, and David discuss the rise of the Democratic Socialists of America with guest Grace Mausser, Co-Chair of the New York City DSA. They talk about its European-style organizing model, its uneasy alliance with the Democratic Party, the primacy of canvassing and volunteering, and the art of compromise. In the latest Gabfest Reads, John Dickerson interviews Maggie Haberman and Jonathan Swan about their new book Regime Change: Inside the Imperial Presidency of Donald Trump. Drawing on extensive reporting from inside the White House, they explore how Trump's second term differs radically from his first, from his decision-making process to the people surrounding him and his relationship with power, money, and the presidency itself. Email your chatters, questions, and comments to gabfest@slate.com. (Messages may be referenced by name unless the writer stipulates otherwise.) Podcast production by Nina Porzucki Research by Emily DittoYou can find the full Political Gabfest show pages here. Want more Political Gabfest? Join Slate Plus to unlock weekly bonus episodes. Plus, you'll access ad-free listening across all your favorite Slate podcasts. You can subscribe directly from the Political Gabfest show page on Apple Podcasts and Spotify. Or visit slate.com/gabfestplus to get access wherever you listen. Find out more about David Plotz's monthly tours of Ft. DeRussy, the secret Civil War fort hidden in Rock Creek Park. Follow@SlateGabfest on X / https://twitter.com/SlateGabfestSlate Political Gabfest on Facebook / https://www.facebook.com/Gabfest/ Hosted on Acast. See acast.com/privacy for more information.
On the heels of the success of GLP-1s like Ozempic, other peptide treatments are flooding the marketplace—and advertising spaces. But even as the Trump administration's FDA discusses approving more treatments and the businesses selling them proliferate, many peptides are sitting in a legal and medical gray area. So how real - and safe - is this peptide hype?Guest: Kate Knibbs, senior writer at WIRED.Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.Podcast production by Rob Gunther, Evan Campbell, Madeline Thames-Ducharme and Patrick Fort.Paige Osburn is the senior supervising producer of What Next and What Next TBD. Hosted on Acast. See acast.com/privacy for more information.
Pediatric Narcolepsy Challenges, Opportunities, and Emerging Therapies On this episode host Amy Lugo, PharmD, BCPS, BC-ADM, FAPhA, FAMCP, Founder and CEO of LoneStar Health Solutions, is joined by Dr. Joshua Lennon, Assistant Professor at the University of Tennessee Health Science Center, to discuss the unique challenges of diagnosing and treating narcolepsy in children. They explore why pediatric narcolepsy is frequently misdiagnosed, the significant delays many patients experience before receiving an accurate diagnosis, and the impact untreated symptoms can have on learning, social development, and long-term health. The conversation also examines current FDA-approved treatment options, promising advances in orexin-targeted therapies, and the important role managed care professionals play in improving timely access to evidence-based care for children living with narcolepsy.
#AD This episode is sponsored by Daré Bioscience. DARE to PLAY™ Sildenafil Cream is a compounded drug. It is not FDA-approved. This product has not been reviewed by FDA for safety or efficacy. It is manufactured in a 503B outsourcing facility under pharmaceutical Good Manufacturing Practices (GMP). Shan sits down with four women to talk about the low libido nobody prepares you for: the 26-year-old who kept saying "I'm supposed to be in my prime" and quietly decided she was broken, the married woman delighting in her season of stillness, and Shan's own reframe that low libido is only a dysfunction if it comes with an F word (frustrating). Then Sabrina Martucci Johnson, founder and CEO of Daré Bioscience, explains what actually happens in the body when desire and arousal stop cooperating, and why women were told for almost 30 years it was all in their heads. Follow Sabrina Martucci Johnson LinkedIn: https://www.linkedin.com/in/sabrina-martucci-johnson/ TikTok: https://www.tiktok.com/@sabrinadareceo Follow Daré Bioscience LinkedIn: https://www.linkedin.com/company/dare-bioscience Instagram: https://www.instagram.com/darebioscience/ —- Learn more about DARE to PLAY™ https://daretoplaybio.com/ Unlock deeper pleasure with a roadmap designed for you — all it takes is 5 minutes. Go to https://beduc.at/bg2631-boody to learn more! Follow Indigo MateoInstagram: https://www.instagram.com/indigomateoMusic: http://www.indigomateo.com/ Follow Jamille McClendonInstagram: https://www.instagram.com/thahealingfactor Follow Saraijah BarnesInstagram: https://www.instagram.com/Rai.destinei Follow Brittany Johnsonhttp://instagram.com/brittbekountry Want more LOVERS? Follow Shan on Instagram → http://instagram.com/shanboodram Get a free Love Letter from Shan → http://loversbyshan.com/newsletter Join the LOVERS Community → https://www.loversbyshan.com/community Explore free quizzes + worksheets → http://loversbyshan.com/quizzes Learn more about your ad choices. Visit megaphone.fm/adchoices
Purple Pants Podcast | Casual Tea: Conspiracies, Comebacks & Chaos The tea is flowing this week as Brice is joined by investigative journalist Justin Carter for another episode of Casual Tea. The duo dives into Jay-Z's Reasonable Doubt 30th anniversary celebration, reflecting on his recent New York performances and upcoming international shows while unpacking the latest theories surrounding Beyoncé's long-awaited Act III era, a rumored Lady Gaga collaboration, and whispers of a Destiny's Child reunion. They also break down the newest developments in the Nolan Wells case before turning to the conversation surrounding Taco Bell, the recent diarrhea outbreak, and the public back-and-forth involving the FDA and CDC. Finally, they react to the internet buzzing over LeBron James “officially joining” the Philadelphia 76ers. From conspiracy theories to breaking headlines and plenty of laughs along the way, it's another unfiltered episode of Casual Tea you won't want to miss. You can also watch along on Brice Izyah’s YouTube channel to watch us break it all down https://youtube.com/channel/UCFlglGPPamVHaNAb0tL_s7g LISTEN: Subscribe to the Purple Pants podcast feed WATCH: Watch and subscribe to the podcast on YouTube SUPPORT: Become a RHAP Patron for bonus content, access to Facebook and Discord groups plus more great perks! Previously on the Purple Pants Podcast Feed: Purple Pants Podcast Archives
Purple Pants Podcast | Casual Tea: Conspiracies, Comebacks & Chaos The tea is flowing this week as Brice is joined by investigative journalist Justin Carter for another episode of Casual Tea. The duo dives into Jay-Z's Reasonable Doubt 30th anniversary celebration, reflecting on his recent New York performances and upcoming international shows while unpacking the latest theories surrounding Beyoncé's long-awaited Act III era, a rumored Lady Gaga collaboration, and whispers of a Destiny's Child reunion. They also break down the newest developments in the Nolan Wells case before turning to the conversation surrounding Taco Bell, the recent diarrhea outbreak, and the public back-and-forth involving the FDA and CDC. Finally, they react to the internet buzzing over LeBron James “officially joining” the Philadelphia 76ers. From conspiracy theories to breaking headlines and plenty of laughs along the way, it's another unfiltered episode of Casual Tea you won't want to miss. You can also watch along on Brice Izyah's YouTube channel to watch us break it all down https://youtube.com/channel/UCFlglGPPamVHaNAb0tL_s7g Previously on the Purple Pants Podcast Feed:Purple Pants Podcast Archives LISTEN: Subscribe to the Purple Pants podcast feed WATCH: Watch and subscribe to the podcast on YouTubeSUPPORT: Become a RHAP Patron for bonus content, access to Facebook and Discord groups plus more great perks! Learn more about your ad choices. Visit megaphone.fm/adchoices
We like to sign off our show by saying, “Take care of yourselves, take care of each other, and drink some tea.” It's our favorite little motto and it's a great reminder that herbalism and self-care go right alongside mutual aid!In our episode 283: Vetting Your Herbalism Sources: Red Flags & Green Flags, we talked about how it isn't actually bucking the system to ignore the FDA and FTC laws about “telling & selling”. Neither is it a cool rebellious act to turn away from scientific knowledge, modern medical technologies, or even conventional treatments. They each have their place, and herbalism isn't an ‘alternative' to them in the sense of a dichotomous choice – either herbs or science, either herbalism or medicine. We can fit together, and we get better results when we do.But it's certainly true that conventional medicine has problems, and that the system needs some bucking! A system reliant on consumerism – buying your way to better health – always leaves people out. A lot of people. They need help, and we can help them.The best way to do that is a little surprising: take care of each other. Extend our circle of care outside ourselves, outside our family and housemates, and further out into the world. We are all here together, and we can all support one another. And since we're all herbalists here, let's do it with herbs!Three ways to get started:FREE Emergency Preparedness course – Concise and targeted lessons teach you how to prepare for emergencies ranging from hurricanes to wildfires to heatwaves. Learn to construct a modular, no-frills herbal first aid kit, food reserve, and go-bag (or shelter-in-place bag). Understand herbal wound care and all the steps to take for cuts and burns. Anticipate and prepare for the effects of climate disasters in your community, not only to help yourself, but to help others too.SLIDING SCALE Herbal Community Care Toolkit – This 20-hour video course teaches you safe, inexpensive, and accessible herbs which can make a difference in the most common health concerns in our society today. High blood pressure, diabetes, edema, pain, poor sleep – there are herbs to support people facing all of these challenges and more. They don't need to be expensive, exotic, or risky. They don't need to be “maximum strength” or “100x concentrated”. Gentle, simple, safe herbs can help people you know and love.SLIDING SCALE Accessible Herbalism course – We consider this essential training for clinical herbalists, but you don't have to be one to want this information! Providing care to everyone is challenging, and involves a lot of creativity and skill to find the right resources and get them to the right people – and to do it all without burning out. To do it, we teach strategies to work around resource constraints, addressing the realities of time and energy involved in herbal work. We share our methods for finding funding, improving access to care, and building community support networks: mutual aid for herbalists and the communities they serve.You can go deeper, of course! These are starting points to get you helpful and empowered as soon as possible, while keeping safety first. And don't forget…Everything's on sale in July!All our offerings are self-paced online video courses. They all come with free access to twice-weekly live Q&A sessions with us, lifetime access to current & future course material, open discussion threads integrated in each lesson, an active student community, study guides, quizzes & capstone assignments, and more!Use code CATNIP at checkout to get 20% off!If you have a moment, it would help us a lot if you could subscribe, rate, & review our podcast wherever you listen. This helps others find us more easily. Thank you!!Our theme music is “Wings” by Nicolai Heidlas.Support the showYou can find all of our online herbalism courses at online.commonwealthherbs.com!
The pharma rep with the free lunch is gone. What replaced it is harder to see, and aimed at you and your doctor. Martha Rosenberg is an investigative reporter who has worked at two medical schools and two medical ad agencies, seeing drug marketing from the inside. This episode is based on her article "3 new pharma marketing tactics every physician should know," published on KevinMD. Reporting from a pharma conference, Martha breaks down three tactics drug makers no longer hide. You will hear how AI apps track where a prescriber sits on the "prescription journey," how disease mongering and TikTok influencers turn everyday worries into conditions worth medicating, and how the industry is shifting from "ask your doctor" ads to pop-up and online practices that sell straight to patients and sidestep the FDA. She also flags a Maryland bill that would force disclosure of pharma funding behind patient advocacy groups. Press play to learn how to spot the marketing dressed up as medicine, and why your skepticism is the best defense you have. Partner with me on the KevinMD platform. With over three million monthly readers and half a million social media followers, I give you direct access to the doctors and patients who matter most. Whether you need a sponsored article, email campaign, video interview, or a spot right here on the podcast, I offer the trusted space your brand deserves to be heard. Let's work together to tell your story. PARTNER WITH KEVINMD → https://kevinmd.com/influencer SUBSCRIBE TO THE PODCAST → https://www.kevinmd.com/podcast
Saying goodbye to JCD. Andrew’s Tribute. Growing up Dvorak with JC. Plenty of financial news to discuss. PLUS we are now on Spotify and Amazon Music/Podcasts! Click HERE for Show Notes and Links DHUnplugged is now streaming live - with listener chat. Click on link on the right sidebar. Love the Show? Then how about a Donation? PayPal.Donation.Button({ env:'production', hosted_button_id:'JJJHP2GDEJC7J', image: { src:'https://www.paypalobjects.com/en_US/i/btn/btn_donateCC_LG.gif', alt:'Donate with PayPal button', title:'PayPal - The safer, easier way to pay online!', } }).render('#donate-button'); Follow John C. Dvorak on Twitter Follow Andrew Horowitz on Twitter Warm-Up - JCD - Through Our Eyes - Andrew's Tribute - No Agenda/DHU Meet Up - 8-8 at 3:33 PM in Ft Lauderdale... - The winner of the SpaceX CTP - and you do not want to miss this one - stay tuned for freaky coincidences on this .... NO Agenda / DHUnplugged Meet-Up (Saturday - 8-8-2026 @ 3:33PM) - Location to be determined - SIGN UP HERE Meet-Up Invite Markets -Back to SpaceX - What a rug pull! (down $1.2T from high) - Semiconductor enter a bear market - down 25% from high - NASDAQ 100 in correction JC Dvorak - A look back on growing up Dvorak Listener thoughts NVDA - De-crowned - Apple is now (once again) the largest stock by market cap - This is probably due the concern around spend and Capex - BUT, is this just a safety trade / rotation? NVIDIA MAY BECOME OPENAI'S BANK - Nvidia may guarantee up to $250 billion in financing for OpenAI. - The proposed Ohio data-center project could cost more than $500 billion. - Nvidia would be helping finance a major customer buying its infrastructure. - The structure raises concerns about circular AI demand. - Nvidia shares fell about 5% as investors weighed the risks. OR - Is this now becoming known as an issue: Circular Financing BIG TECH GETS THE CAPEX FLU - Alphabet beat earnings estimates, but shares fell about 7%. - Management raised 2026 capital spending guidance to as much as $205 billion. - Google Cloud revenue rose more than 80% to about $25 billion. - Alphabet posted negative quarterly free cash flow for the first time since its IPO. - Tesla fell more than 14% as investors focused on weaker profit and heavy spending. CHINA'S CHIP IPO GOES FULL CASINO - Chinese chipmaker CXMT jumped about 500% in its market debut. - The company raised about $8.6 billion. - It was Asia's largest IPO of the year. - A small public float helped amplify the move. - U.S. semiconductor stocks fell as investors weighed stronger Chinese competition. THE FED MEETING WITH NO EASY ANSWER - The Federal Reserve meets Wednesday. - Markets are split between no change and a possible rate increase. - Higher oil prices have raised inflation concerns. - Treasury yields are near their highest levels since early 2025. - The decision arrives with big-tech earnings and GDP data. AI MONEY GOES IN CIRCLES - Microsoft, OpenAI and Nvidia are linked through funding, chips and cloud deals. - The same capital can appear as investment, demand and revenue. - Suppliers are helping finance customers that buy their own products. - The risk is a chain reaction if AI funding or demand slows. OPENAI'S MODEL GOES ROGUE - OpenAI said a model acted outside expected controls during testing. - The incident reportedly caused a breach at a startup. - The case goes beyond a bad answer or chatbot hallucination. - It raises questions about giving AI agents access to real systems. - Regulators may push for stronger testing and disclosure rules. GOOGLE WANTS YOUR SELFIE - Google will allow account sign-ins using selfie video. - The feature adds another way to verify identity. - It could reduce dependence on passwords and recovery codes. - The tradeoff is greater use of facial data. - Privacy, storage and security questions will follow. TESLA AND ALPHABET GET HAMMERED - Tesla fell 13% and Alphabet dropped 7%. - Investors focused on rising costs and heavy AI spending. - Strong revenue was not enough to calm return-on-investment concerns. - The market wants clearer proof that spending will produce cash flow. - Expensive growth stories are getting less patience. TESLA PROFIT MISSES - Tesla's second-quarter profit fell well short of estimates. - Rising costs weighed on the results. - Spending remains high across vehicles, AI and robotaxis. - Investors are questioning when those projects will improve margins. - Softer robotaxi language added to the pressure- and of course when is the real question - promising for years. TESLA COOLS THE ROBOTAXI TALK - Tesla has become more cautious about robotaxi timing and expansion. - Earlier comments suggested a much faster rollout. - Safety, regulation and reliability remain major obstacles. - Robotaxis are still central to Tesla's long-term valuation. - More delays would weaken one of the company's biggest growth claims. SPACEX SHORT SELLERS CASH IN - Short sellers reportedly earned $15.5 billion as SpaceX shares fell. - The move rewarded investors betting against the company's valuation. - It shows how quickly enthusiasm can reverse at extreme prices. - SpaceX still has strong growth stories in launches and satellites. - The debate is whether too much future success was already priced in. --- Price hit $108 today before bouncing - major rug pull CATHIE WOOD DOUBLES DOWN ON SPACEX - Cathie Wood called SpaceX potentially the most important company in history. - Her comment came after a sharp decline in the shares and it seems is more of talking her book. - Her case rests on launch, satellite and communications growth. - The problem is that losses are expected for the foreseeable future. INTEL FINALLY GETS AN AI LIFT - Intel shares jumped 11% after earnings. - Revenue grew at the fastest pace in almost 15 years. - AI-related demand helped drive the improvement. - The report gave investors fresh evidence of a turnaround. - Intel still trails key rivals in advanced chips and manufacturing. - However, it turned lower in the morning and now is 35% off its high TSMC ADDS ANOTHER $100 BILLION - TSMC plans another $100 billion investment in Arizona. - Second-quarter profit surged 77%. - AI-chip demand continues to drive the expansion and the idea is that the project strengthens U.S. semiconductor production. - It also adds labor, construction and execution risk. - The spending shows the scale of the AI infrastructure race. --- So far many of these promises have been a bit hallow BOND YIELDS FEEL THE OIL SHOCK - The 10-year Treasury yield reached its highest level since January 2025. - Surging oil prices brought inflation fears back into the market. - Higher energy costs could delay Federal Reserve rate cuts. - Rising yields pressure stocks, housing and other rate-sensitive assets. - Oil is again influencing the entire interest-rate outlook. CANADA GETS A 50% TARIFF - Trump imposed 50% tariffs on some Canadian goods. - The administration cited discrimination against U.S. companies. - The move could raise costs for manufacturers using Canadian inputs. - Canada could respond with tariffs of its own. - The fight adds more uncertainty to North American trade. WILDFIRE SMOKE BECOMES A TARIFF ISSUE - Trump criticized Canada as wildfire smoke spread into the U.S. - He said pollution costs could be added to tariffs. - The idea links environmental damage directly to trade policy. - Canadian goods could face another unpredictable cost. - Companies may struggle to price a pollution-based tariff. MIAMI TURNS INTO A BUYER'S MARKET - Miami reportedly has 140% more home sellers than buyers. - Buyers now have more leverage on price, inspections and concessions. - The reversal follows one of the country's strongest pandemic housing booms. - High prices, insurance and carrying costs may be pushing demand lower. - Starting to see some pricing erosiokn and sellers pulling homes UNITEDHEALTH TURNS THE CORNER - UnitedHealth beat earnings estimates and raised its outlook. --- Co-Pick for JCD and AH - Cost controls helped drive the improvement. DELTA SAYS HIGHER FARES ARE STICKING - Delta expects higher airfares to continue. - Strong pricing could help it reach its 2026 profit goal. - Higher fares provide protection against fuel and labor costs. - Travelers may see fewer discounted tickets. - Capacity growth remains the key variable. --- Say it enough and its true? THE GREAT EGG RECALL - Nearly 1.6 million dozen eggs were recalled over possible salmonella. - The FDA announced the recall after identifying contamination concerns. --- Now what will be the political angle? - Supply disruption could also add pressure to egg prices. HUMAN SKIN ENTERS K-BEAUTY -Injectable skin boosters derived from donated cadaver skin to regenerate aging skin tissue - Human skin is becoming part of some K-beauty treatments. - Demand is tied to premium anti-aging products. - South Korean biotech firm L&C Bio manufactures the treatment, producing roughly 80,000 vials per month as demand outpaces supply. -- They are nuts in Korea NETWORKS SKIP TRUMP SPEECH - ABC, NBC and CNN declined live primary-channel coverage. - The speech focused on0 'election security'. - Networks weighed news value against misinformation concerns. - The decision could affect ratings and political advertising during mid-terms which JCD was the biggest income for any news outlet (Political elections) Love the Show? Then how about a Donation? PayPal.Donation.Button({ env: 'production', hosted_button_id: 'JJJHP2GDEJC7J', image: { src: 'https://www.paypalobjects.com/en_US/i/btn/btn_donateCC_LG.gif', alt: 'Donate with PayPal button', title: 'PayPal - The safer, easier way to pay online!' } }).render('#donate-button-2'); THE CLOSEST TO THE PIN for SpaceX (SPCX) Winners will be getting great stuff like the new "OFFICIAL" DHUnplugged Shirt! FED AND CRYPTO LIMERICKS See this week's stock picks HERE Follow John C. Dvorak on Twitter Follow Andrew Horowitz on Twitter
Amanda Calabrese was a middle schooler at a swim meet when she got her period for the first time. Her team captain told her to figure it out in thirty minutes or she was off the relay. That moment stuck with her all the way to Stanford, where she met her future co-founder Greta Meyer and started sketching what would become Sequel, the first tampon redesign in nearly a hundred years. On this episode of She Pivots, Amanda talks about the four-year fight to get a tiny piece of cotton past the FDA, why she treats the tampon as game-day equipment rather than something to whisper about, and how Sequel landed in locker rooms from middle schools to Audi Field, Yankees Stadium, and the Indiana Fever. Now a nine-time champion turned product design engineer, Amanda is on a mission to change how period care is talked about in sports and in every space where women show up to compete. Chapters: 00:00 Welcome to She Pivots 01:46 Amanda's Childhood in East Hampton 05:43 From Junior Lifeguard to National Champion 12:14 The Challenges of Periods in Sports 16:09 Amanda's Journey to Product Design 21:01 The Birth of Sequel and the Spiral Tampon 27:02 Overcoming Obstacles and Securing Funding 29:37 The Evolution of Tampon Design 35:44 The Power of Self-Awareness in Team Building 38:13 Navigating the Challenges of Fundraising 42:16 The Rise of Women's Sports and Sequel's Timing 48:12 The Future of Sequel and Period Care 49:46 Low Point to Launch 50:52 Closing Thoughts 51:44 Podcast Credits You can keep up with Amanda’s work with sequel at www.trysequel.com Be sure to subscribe so you never miss a pivot story, leave us a rating (it really helps!), and share this episode with a woman in your life who you think needs a little inspiration. She Pivots is a podcast created by host Emily Tisch Sussman to highlight influential women voices, share stories of bold career moves, and inspire women with interviews about career reinvention and how personal pivots can redefine professional success. Join our Substack community! Subscribe here for exclusive content and to connect with other pivoters: shepivots.substack.com Learn more about the inspiring women in our pivoter community by following us on instagram @ShePivotsThePodcast, and check out our website shepivotspod.com for resources and updates. She Pivots is proud to be an iHeart podcast.Support the show: https://www.shepivotsthepodcast.com/See omnystudio.com/listener for privacy information.
On this episode of Vitality Radio, Jared launches a brand-new series called Free Medicine by exploring one of the simplest habits with the potential to transform long-term health: daily push-ups. Learn how a few minutes of resistance exercise each day can help support healthy muscle mass, bone strength, cardiovascular fitness, blood sugar metabolism, posture, cognitive function, and healthy aging. Jared explains the science behind mTOR activation, sarcopenia, BDNF, and why maintaining muscle becomes increasingly important after age 50. He also shares practical tips for building lasting habits, modifying push-ups for every fitness level, and supporting your efforts with adequate protein and creatine. If you've been looking for a free, effective place to begin improving your health, this episode is a great place to start.Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.This podcast is produced by DrTalks.comhttps://drtalks.com/podcast-service/
Naturopathic gastroenterologist Mark Davis, ND (FABNG), discusses his work in fecal microbiota transplantation (FMT), research, and integrative approaches to GI disease. Davis explains FMT history, screening criteria, delivery methods, how it differs from probiotics, and why it is highly effective for recurrent C. difficile (about a 90% durable cure), while noting FDA-approved products (Rebyota, Vowst) and off-label applications. He describes IRB-approved studies on naturopathic care for IBS and ulcerative colitis and a blinded project comparing consistency across 15–20 stool microbiome labs. The conversation covers evidence for diet in IBS/IBD (including SCD and a semi-vegetarian diet), low-FODMAP as a temporary tool, breath testing and relapse in SIBO, helminthic therapy options and legality, targeted probiotics (Saccharomyces boulardii, Akkermansia, soil-based species), enema therapies, indigo naturalis benefits and risks, saffron evidence for mood, telemedicine practice, and a crowdfunding platform for clinical trials.
Three years after his first appearance, Butterfly Network CEO Joe DeVivo returns to catch Harry up on the roadmap. Butterfly's ultrasound-on-a-chip has evolved from a single handheld device into a foundational semiconductor platform that third parties can build on. The most dramatic example: Midjourney's full-body scanner, which rings 40 Butterfly chips around the body for whole-body tomographic imaging. Joe and Harry dig into what's real today versus what's coming, the physics of ultrasound, the path from demo to FDA clearance, and the business logic of "multiple shots on goal." In this episode: The chip as a platform: opening Butterfly's technology to third-party developers (the "Nvidia moment"). Midjourney's full-body scanner: tomography, 400 teraflops of data, and a roadmap toward a one-minute scan with the Apollo chip. Real-world impact: 1,500 midwives trained in Kenya and South Africa, plus a new FDA-cleared gestational-age AI tool. Partners beyond Midjourney: vascular robotics, fatty liver diagnosis, and brain-computer interfaces (including "silent speech"). Physics Q&A: why 360-degree imaging solves ultrasound's problems with air and bone. The hospital shift: capturing "ghost" scans, Compass AI, and at-risk skilled-nursing deployments. The 10-year vision: imaging that comes to the patient instead of the patient going to imaging. Chapters: (00:01) A roadmap from three years ago (00:31) Midjourney unveils a full-body scanner (01:31) Joe DeVivo returns (02:59) What shipped: the chip becomes foundational (04:52) Opening the platform to third parties (06:34) Kenya and South Africa: midwives and the FDA-cleared gestational-age app (11:11) FDA rigor and validating AI (14:52) Butterfly Garden, Butterfly Embedded, and the nine partners (16:53) Brain-computer interfaces and silent speech (22:00) The Midjourney deal: origin and reaction (24:03) Tomography explained (28:12) What 40 chips can see and the data challenge (29:33) The roadmap to a one-minute scan; the Apollo chip (32:43) AI looking for a physical carrier (34:31) Prototype to product: milestones to clearance (38:28) Wellness first, then regulatory clearances (39:03) The physics of air and bone (41:45) The investment thesis: multiple shots on goal (46:26) The business today: Compass AI and health-system deployments (49:54) Heart-failure monitoring and at-risk skilled nursing (53:49) The 10-year view: imaging comes to the patient (57:18) Why early detection matters (59:50) Closing About the guest: Joe DeVivo is CEO of Butterfly Network and has spent 35 years in medical devices. Also mentioned: Harry's book, The Invisible Interface: How AI Turns Intentions into Actions and Who Wins (foreword by Don Norman), available in print and ebook.
Dentistry is becoming more stressful than ever, and the effects go far beyond a busy schedule. Burnout, anxiety, depression, and chronic stress are impacting more dentists than many realize. In this conversation, Dr. Kristin Yont shares her personal journey through overwhelming stress and explains how it led her to discover evidence based strategies that transformed both her career and her life.Learn how chronic stress changes the brain, why burnout affects leadership and decision making, and what practical techniques can help dentists stay resilient.From breathing exercises and mindfulness to emotional intelligence and healthier daily habits, this episode explores simple tools that can improve mental wellbeing, strengthen leadership, and create a more sustainable career in dentistry. Whether you own a practice or are early in your dental journey, this discussion offers valuable insights to help you perform at your best while protecting your health.Connect with Dr. Kristin Website: mindbodyteacher.com--------------Stop feeling overwhelmed by the numbers. ADCPA member firms specialize exclusively in serving dentists to help you achieve financial success. Gain a strategic partner who understands industry benchmarks and overhead management so you can focus on clinical excellence. Find your expert: Visit https://adcpa.org/ to find a trusted dental CPA near you. Your numbers should work as hard as you do.--------------Detect what traditional diagnostics miss. Innerview uses FDA-cleared technology to measure internal tooth mobility, helping you identify cracks and loose restorations earlier before they become emergencies. The result is better treatment planning, fewer surprises, and stronger patient trust, all without disrupting your workflow.Book a demo at Innerview.ai and mention Art Wiederman to receive $250 off.
America's Food Safety Crisis: Cyclospora, Salmonella and Trump-Era Cuts More than 11,000 Cyclospora cases nationwide, a multistate salmonella outbreak linked to eggs—and critical questions about the safety of America's food supply. Why are foodborne illnesses spreading, why has identifying their sources proved so difficult, and what role could federal cuts to food-safety surveillance play? Karel examines the outbreaks, America's regulatory system and why the United States appears unable to keep its food supply safe. Also in this episode: Could AI apps that simulate dead loved ones or pets help people cope—or prevent them from grieving and moving forward? And does watching too much television actually harm your brain? New research offers a troubling answer. Support The Karel Cast: https://patreon.com/reallykarel Watch, like and subscribe: https://youtube.com/reallykarel The Karel Cast streams live Monday through Thursday at 10:30 a.m. Pacific and is available on Apple Podcasts, iHeartRadio, Spotify, Spreaker, TikTok and Instagram. Karel is a history-making broadcaster and entertainer based in Las Vegas with his service dog, Ember. #FoodSafety, #Cyclospora, #CyclosporaOutbreak, #Salmonella, #SalmonellaOutbreak, #EggRecall, #FoodborneIllness, #PublicHealth, #USFoodSupply, #FoodSafetyCrisis, #FDA, #CDC, #TrumpAdministration, #GovernmentCuts, #FoodInspection, #ConsumerSafety, #BreakingNews, #HealthNews, #PoliticalCommentary, #CurrentEvents, #ArtificialIntelligence, #AIGrief, #GriefTechnology, #DigitalAfterlife, #MentalHealth, #BrainHealth, #Television, #DementiaResearch, #TheKarelCast, #ReallyKarel https://youtube.com/live/LUf6iI9YWw4
Nate Stasko, CEO of Vast Therapeutics, is developing a novel nitric oxide-releasing therapy to treat chronic respiratory diseases, particularly fibrosis bronchiectasis, which is frequently misdiagnosed as asthma or COPD. Their lead drug candidate is a dual-mechanism therapy that is delivered to the lungs via a nebulizer to target both infection and inflammation with the potential to eradicate pathogens rather than just suppressing them. This approach, in early trials, is showing excellent tolerability and eliminates the need for chronic antibiotic use, which carries the risks of toxicity and contributes to antibiotic resistance. Nate explains, "At Vast Therapeutics, our main idea and goal as a company is to come up with better solutions for the 500 million people worldwide who suffer from chronic respiratory disease. And there is a new disease getting a lot of attention that we're targeting with our lead program called bronchiectasis, and it's often been misdiagnosed as asthma or COPD. And now over a million patients in the US are being diagnosed with bronchiectasis. And the whole campaign is to teach physicians and the whole medical community to suspect this disease over some of these other misdiagnosed diseases." "Traditionally, patients have been managed with either antibiotics to calm down the infection, but you know the problems of chronic antibiotic use- the liver toxicity, kidney toxicity, and hearing loss associated with long-term antibiotic use are just bad for these patients. Not to mention we have the global problem of antibiotic resistance. And so giving a 52-week course of therapy of antibiotics is less than ideal. And then recently, just last year, there's some hope for these patients where there was a new drug approved called brensocatib, which was the first drug ever approved for bronchiectasis by the FDA. And so now it targets the inflammation." "Having the ability to target two mechanisms of action would be the best therapy. And that's actually what Vast is developing. We're using the body's own ability to make and produce nitric oxide, which is a miracle molecule. And we're delivering nitric oxide back to these patients to target both the infection and inflammation at the same time and improve the overall standard of care for these patients." #VastTherapeutics #Bronchiectasis #Pulmonology #NitricOxide #RespiratoryMedicine #AntimicrobialResistance #ALX1#ChronicLungDisease #HealthcareInnovation #ClinicalTrials vasttherapeutics.com Download the transcript here
Nate Stasko, CEO of Vast Therapeutics, is developing a novel nitric oxide-releasing therapy to treat chronic respiratory diseases, particularly fibrosis bronchiectasis, which is frequently misdiagnosed as asthma or COPD. Their lead drug candidate is a dual-mechanism therapy that is delivered to the lungs via a nebulizer to target both infection and inflammation with the potential to eradicate pathogens rather than just suppressing them. This approach, in early trials, is showing excellent tolerability and eliminates the need for chronic antibiotic use, which carries the risks of toxicity and contributes to antibiotic resistance. Nate explains, "At Vast Therapeutics, our main idea and goal as a company is to come up with better solutions for the 500 million people worldwide who suffer from chronic respiratory disease. And there is a new disease getting a lot of attention that we're targeting with our lead program called bronchiectasis, and it's often been misdiagnosed as asthma or COPD. And now over a million patients in the US are being diagnosed with bronchiectasis. And the whole campaign is to teach physicians and the whole medical community to suspect this disease over some of these other misdiagnosed diseases." "Traditionally, patients have been managed with either antibiotics to calm down the infection, but you know the problems of chronic antibiotic use- the liver toxicity, kidney toxicity, and hearing loss associated with long-term antibiotic use are just bad for these patients. Not to mention we have the global problem of antibiotic resistance. And so giving a 52-week course of therapy of antibiotics is less than ideal. And then recently, just last year, there's some hope for these patients where there was a new drug approved called brensocatib, which was the first drug ever approved for bronchiectasis by the FDA. And so now it targets the inflammation." "Having the ability to target two mechanisms of action would be the best therapy. And that's actually what Vast is developing. We're using the body's own ability to make and produce nitric oxide, which is a miracle molecule. And we're delivering nitric oxide back to these patients to target both the infection and inflammation at the same time and improve the overall standard of care for these patients." #VastTherapeutics #Bronchiectasis #Pulmonology #NitricOxide #RespiratoryMedicine #AntimicrobialResistance #ALX1#ChronicLungDisease #HealthcareInnovation #ClinicalTrials vasttherapeutics.com Listen to the podcast here
Nearly 7,000 people sick, a recalled lettuce supply, and an FDA test result that got quietly walked back — Dr. Adam Brockman digs into the outbreak nobody's fully explaining. Then, a viral story about midlife husbands and the health habits driving couples apart — and why it's really about vitality, not vanity. Plus, brand-new science on nano-curcumin's surprising fight against parasitic infection, straight from your spice rack. And to close it out, an unsolved mystery: dozens of Grand Canyon rafters mysteriously falling ill, with no answer yet in sight. Real headlines, real science, and the small habits that make all the difference — this hour of Health Talk America has it all.Health Headlines of the WeekHealth Alternative of the WeekHealth Mystery of the Week
An FDA panel has recommended allowing compounding pharmacies to make six unapproved peptides. Dr. Sanjay Gupta and CNN Health's John Bonifield discuss their popularity, safety concerns and what comes next. This episode was produced by Madeleine Thompson and Leying Tang. Medical Writer: Andrea Kane Showrunner: Dan Bloom Technical Director: Dan Dzula Sr. Director of Podcasts: Zach Goldbaum Learn more about your ad choices. Visit podcastchoices.com/adchoices
Urologist Dr. Alex Tatum on Girth Enhancement, Testosterone, and Peptide Therapy Most men will never ask their doctor the questions this episode answers. From safe, non-surgical girth enhancement to daily testosterone dosing to the peptides fighting for FDA access right now, this conversation covers what actually works, what's dangerous, and what your doctor probably won't bring up first. Host Dave Asprey sits down with Dr. Alex Tatem, a board-certified urologist with fellowship training in male sexual and reproductive medicine. Dr. Tatem has built his practice and his YouTube following around pushing medicine beyond what the traditional medical establishment allows, with a focus on male girth enhancement, performance enhancement, peptides, and PEDs. They break down the real science behind penis enhancement, including why length surgery still does not exist, how hyaluronic acid injections safely increase girth, and why silicone and PMMA fillers have left men permanently disfigured. Dave and Dr. Tatem also get into cutting-edge testosterone dosing strategies, the peptides driving the biggest gains in human performance and longevity, including BPC-157, TB-500, SS-31, and MOTS-c, and why PT-141 has become the most talked-about peptide for libido and sexual health. You'll Learn: Why hyaluronic acid injections have become the safest, most reproducible method for girth enhancement The truth about penis enlargement surgery, and why length enhancement still has no reliable surgical fix How daily microdosed testosterone compares to traditional weekly TRT protocols Why PT-141 and melanotan II are being used for libido, nitric oxide release, and even prostate health How BPC-157, TB-500, SS-31, and MOTS-c are changing recovery, mitochondria function, and metabolism The dangerous enhancement trends to avoid, including silicone implants and unregulated fillers Why the fight over peptide access at the FDA could determine the future of functional medicine and supplements in America Thank you to our sponsors! - Just Thrive | Get a free 90-day supply of Digestive Bitters (a $90 value) when you start a 90-day Just Thrive Probiotic subscription at https://get.justthrivehealth.com/pages/asprey - KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off - PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off. - ALP | Head to http://alppouch.com/ and use code DAVE for 20% off your first order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: penis girth enhancement hyaluronic acid, penis enlargement that actually works, average penis size urologist, PT-141 for libido, melanotan II peptide, BPC-157 benefits, TB-500 for injury recovery, SS-31 dosing, MOTS-c peptide FDA, daily subQ testosterone dosing, oral testosterone undecanoate, TRT dosing protocols, Anavar for muscle recovery, silicone penile implant risks, PMMA filler complications, is penis enlargement surgery safe, hyaluronic acid girth injection cost, Dr. Alex Tatem urologist, peptides FDA regulation 2026 Resources: • Check Out Dr. Tatem's Content At: https://www.youtube.com/@DrAlexTatem • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15? • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 03:10 – Penis Enhancement Intro 13:32 – Dangerous Enhancement Methods 22:49 – Girth Procedure Explained 29:56 – Why Demand Is Rising 32:09 – Peptides for Men 41:26 – TRT and Testosterone 50:35 – Peptide Regulation Fight See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Kara and Scott discuss Paramount's decision to pause its merger with Warner Bros. Discovery, and predict whether the blockbuster deal will ultimately go through. Then, Meta's latest ad campaign puts an optimistic spin on AI, but Scott has a few ideas for better taglines. Plus, Trump's White House Correspondents' Dinner jokes fall flat, and the FDA's decision to ease restrictions helps fuel America's peptide boom. Watch this episode on the Pivot YouTube channel.Follow us on Instagram and Threads at @pivotpodcastofficial.Follow us on Bluesky at @pivotpod.bsky.socialFollow us on TikTok at @pivotpodcast.Send us your questions by calling us at 855-51-PIVOT, or email Pivot@voxmedia.com Learn more about your ad choices. Visit podcastchoices.com/adchoices
The government wants you to believe America's food safety system is working. But this latest Salmonella outbreak tells a very different story. Nearly 100 Americans across 17 states have gotten sick. Twenty six have been hospitalized. The source? Eggs from a massive industrial producer. Here's the question nobody in Washington seems willing to answer. If the company found Salmonella in its own testing, why did Americans continue getting sick for months before a recall was finally issued? This outbreak stretches back more than seven months before the government finally acted. Seven months. That is an unacceptable lapse in oversight. Instead of moving immediately to protect consumers, the FDA once again appears to have allowed contaminated products to remain in the marketplace while families unknowingly put them on their breakfast tables. We'll examine why it took so long, whether America's food safety system is relying too heavily on voluntary reporting, and why regulators continue to react instead of preventing these outbreaks in the first place. Americans deserve answers, accountability, and a government that moves faster than the spread of dangerous bacteria. And one more thing. Salmonella can be especially dangerous for seniors, young children, and those with weakened immune systems. While most healthy adults recover with fluids and rest, some cases require prescription antibiotics like azithromycin. That's one reason I recommend being prepared before an emergency happens. The Wellness Company's Medical Emergency Kit includes physician-prescribed medications for situations where access to care may be delayed. You can learn more at twc.health/grant and save 10% with promo code GRANT.See omnystudio.com/listener for privacy information.
In this episode of the Habit-Based Lifestyle Podcast, host Jesse Ewell welcomes Dr. Solomon Jon, a board-certified family medicine physician and expert in peptides. Dr. Jon shares his personal journey from traditional medicine to exploring the world of peptides and wellness. He discusses the challenges he faced in the medical community regarding the acceptance of peptides, the common mistakes people make when using them, and the importance of understanding dosing and sourcing. The conversation emphasizes the need for a balanced approach to health, integrating both traditional and innovative methods for optimal wellness. In this conversation, Jesse and Solomon dive into the complexities of weight loss, the importance of support systems, and the evolving landscape of peptide therapies. They discuss the potential future of peptides in healthcare, the challenges posed by big pharma, and the need for more regulations. The conversation also touches on personal health habits and the impact of various peptides on health and wellness. Takeaways: • Dr. Solomon Jon transitioned from traditional medicine to wellness after personal health challenges. • Peptides can offer significant benefits for health and wellness, but they require proper understanding and application. • The medical community is often skeptical about peptides due to a lack of evidence and education. • Common mistakes in using peptides include not understanding dosing and sourcing. • It's essential to identify personal health goals before using peptides. • Dosing for peptides is not standardized, making it crucial to work with knowledgeable providers. • The future of peptides in medicine may involve more regulation and acceptance in the medical community. • Personal experience in health can enhance a provider's credibility and effectiveness. • Education and open-mindedness are vital in the evolving landscape of health and wellness. • The conversation around peptides is just beginning, and more professionals need to engage with this topic. Weight loss requires more than just a quick fix; habits matter. • Support systems are crucial for successful weight management. • Peptides can be life-changing when used correctly. • The FDA's role will shape the future of peptide therapies. • Big pharma faces challenges in patenting natural compounds. • The health industry resembles a 'Wild West' scenario. • Foundational health practices are essential for effective treatment. • GLPs show promise in metabolic health and weight loss. • Oral delivery of peptides could revolutionize their use. • Education and awareness about peptides are vital for practitioners. Reach out to Solomon Jon on Instagram Learn more about Jesse though the following links: HBL Lifestyle Secrets Group on Facebook Personal Website HBL Website Instagram Email
Psychedelic Therapy for Mental Health: Research, Safety, and the Path to FDA Approval: Dr. Will Van Derveer and Keith Kurlander, co-authors of “Psychedelic Therapy: A Revolutionary Approach to Restoring Your Mental Health and Reclaiming Your Life,” reveal the shift from recreational psychedelics to structured, research-based psychedelic-assisted therapy for conditions like PTSD, depression, and anxiety. Van Derveer describes limitations of conventional psychiatry (citing STAR*D remission rates) and his entry into MDMA-assisted PTSD research after promising results. They contrast controlled clinical protocols—screening, preparation, safe setting, trained facilitation, medical monitoring, and post-session integration—with uncontained recreational use. The discussion covers current policy momentum under Trump and RFK Jr., VA interest for veterans, and key agents: ketamine (including abuse risks and clinic-only Spravato), MDMA (phase 3 but not approved in 2024), psilocybin (phase 3, potential FDA approval), LSD (GAD trials), ibogaine (arrhythmia risk, Mexico clinics), ayahuasca, peyote, and microdosing. They also note commercialization, including Eli Lilly's acquisition of a 5-MeO-DMT nasal spray developer, and emphasize an integrative “all-of-the-above” mental health approach.
Elena Medo, M.B.A. is an entrepreneur, researcher, and inventor who has spent nearly 40 years transforming neonatal care through leadership and innovation. She has secured numerous patents, raised over $40 million across four companies, and built a legacy of firsts, including the first commercially available shelf-stable donor breast milk product; the first milk bank owned exclusively by nursing mothers; and the first medical device designed to analyze human milk. Today, as CEO and co-founder of Leonie Health PBC, established in 2023 with her daughter, Adrianne Weir, Elena is developing a revolutionary product that replicates the immune properties of colostrum to protect preterm infants against the three deadliest neonatal infections—necrotizing enterocolitis (NEC), ventilator-associated pneumonia (VAC), and sepsis—which together claim the lives of more than 30,000 hospitalized infants per year. Elena's work is driven by an unwavering commitment to ensure that human milk's unparalleled bioactive benefits reach the world's most vulnerable patients. Companies she has founded—including Prolacta Bioscience, Medolac Laboratories, North American Instruments, and White River Concepts—have applied disruptive technologies to serve the 15 million preterm infants born each year. A frequent speaker at neonatal, women's health, and leadership conferences, Elena holds an M.B.A. degree in Healthcare Management from the University of California, Irvine's Paul Merage School of Business and is widely recognized for assembling world-class teams to solve critical challenges in infant health. In this episode of Food Safety Matters, we speak with Elena [38:58] about: Her work in human milk science and the founding of Leonie Health, which offers bioactive infant nutritional products mimicking colostrum to support neonatal health and early development Reflections on the recent global infant formula recall due to cereulide contamination, which affected 99 countries and multiple brands Why U.S. disease surveillance systems might miss or misclassify infant foodborne illness cases What the cereulide incident reveals about risks for infants in neonatal intensive care (NICU) and donor milk settings Improvements to public health and laboratory systems that would enable earlier detection and response to infant formula contamination incidents and related illnesses The importance of infant-specific toxicological reference values for contaminants like cereulide, such as those recently established in the EU, and how the EU's response could influence regulatory approaches to other emerging hazards in infant foods Leonie Health's process for verifying the safety of donor milk Key principles for clinicians, hospitals, and parents to consider when making decisions about infant feeding when contamination events affect commercial formula products. News and Resources News U.S. Cyclosporiasis outbreak [2:46]: Experts Set Record Straight on FoodNet, CDC Cuts as Senators Press RFK Jr. for Answers Amid Cyclospora Outbreak Michigan, Ohio Together Report More than 9,000 Cyclosporiasis Cases; CDC Outbreak Count Exceeds 4,000 Taylor Farms Lettuce Named as Source of U.S. Cyclospora Outbreak How the U.S. Cyclospora Outbreak Reflects a Strained National Foodborne Illness Surveillance System Senator Klobuchar Urges CDC, FDA to Restore Food Safety Programs Amid Cyclosporiasis Outbreak CDC Reports Up to 7,000 Cyclosporiasis Cases Across U.S., Identifies Large Midwestern Outbreak Cluster Cyclospora Cases Climb, But Actual Number Unclear as CDC Reporting Lags Behind States Foodborne Parasite Cyclospora Sickens Thousands Across U.S. Codex Alimentarius news [28:30] Codex Publishes Strategic Plan for 2026–2031 Codex Adopts Internationally Harmonized Precautionary Allergen Labeling at CAC49 Following Infant Formula Incidents, FDA Urges Manufacturers to Implement Stronger, Substantive Supplier Oversight [29:53] USDA-FSIS to Expand Testing for Metals in RTE Foods Under National Residue Program [33:59] Resources Infant formula cereulide contamination incident: EFSA Reviews Cereulide Infant Formula Incident, Says Likelihood of Exposure is Low EFSA Sets Safety Thresholds for Cereulide Toxin in Infant Formula EFSA to Advise on Cereulide Levels in Infant Formula Following Global Recall U.S. Cyclosporiasis outbreak: "Cyclospora cayetanensis: An Emergent Public Health Threat and an Enigma for Traceback Investigation," Food Safety Magazine "Please Don't Stop Eating Vegetables and Fruits Because of Cyclospora," The Washington Post "Cyclospora Spreads Through Human Feces. How Did it Get Into Our Food Supply?" The New York Times "Publisher's Platform: The Traceability Rule was Supposed to be Law in January. This Cyclospora Outbreak Started in May." Food Safety News We Want to Hear from You! Please send us your questions and suggestions to podcast@food-safety.com
Separating Signal from HypePatients bring us lists. Greens powders, magnesium for everything, vitamin D “for immunity,” fish oil, creatine, curcumin… so how do we separate signals from hype without becoming the office that just says “no” to everything? In this home-grown deep dive, we build a practical, patient-centered framework for evaluating any supplement, then pressure-test it against the products patients actually take. Learn a five-question approach to any supplement, how to judge product quality in an industry the FDA does not pre-approve, and where the evidence actually lands on greens powders and multivitamins, magnesium, creatine, vitamin D, fish oil (and why cod liver oil is not the same thing), turmeric/curcumin, and glucosamine/chondroitin.Claim CME for this episode at curbsiders.vcuhealth.org!Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CMEShow Segments Intro Ask These Five Questions: A Framework for Any Supplement Supplement Quality and Regulation Greens Powders and Multivitamins Magnesium Creatine Vitamin D Fish Oil and Cod Liver Oil Turmeric and Curcumin Glucosamine and Chondroitin Simplifying the Regimen Take-Home Points Credits Writer and Producer, Show Notes, Cover Art, Infographic: Paul Wurtz MD. Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP Reviewer: Sai S Achi MD, MBA, FACP Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste DisclosuresThe Curbsiders report no relevant financial disclosures. Sponsor: FIGSCurbsiders listeners can get 15% off. Just go to WearFIGS.com and use code FIGSRX. Sponsor: Panacea FinancialVisit Panacea.Legal/curb to schedule your free consultation.Sponsor:Continuing Education CompanyVisit CMEmeeting.org/curbsiders and use promo code Curb30 for 30% off all online courses and webcasts.
#897: A panel of doctors, experts, and pharmacists recommends the FDA to open up access to peptides in. Tech giants debate whether AI should be open vs. closed source. The Cockroach Party in India shows how social media can affect real change in a country. Lebron is going to Philly. Finally, what you need to know in the upcoming week ahead. Got difficult questions? Head to https://www.claude.ai/mbd to answer them. Get tickets for our trivia tournament! https://caveat.nyc/events/the-morning-brew-trivia-tournament-2026-07-30 Grab tickets to our Performance Revue show! https://www.morningbrew.com/events/brew-performance-revue-2026?utm_campaign=performance_revue_2026&utm_source=mbd Subscribe to Morning Brew Daily for more of the news you need to start your day. Share the show with a friend, and leave us a review on your favorite podcast app. Listen to Morning Brew Daily Here: https://www.swap.fm/l/mbd-note Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Jeff Gross, a board-certified neurosurgeon and founder of Recelebrate, joins the show to demystify peptides and regenerative medicine. He explains how frustration with the traditional healthcare system pushed him from surgery toward cellular-level healing, and breaks down what peptides actually are, why "FDA approved" is widely misunderstood, and how stem cells and exosomes work in the body. The conversation covers real-world applications — from joint and cartilage regeneration to Parkinson's symptom relief and mitochondrial repair with peptides like SS-31 and MOTS-C. Dr. Gross also tackles misconceptions around legality, telehealth treatment options, and how to vet a regenerative medicine clinic. It's a wide-ranging, myth-busting conversation for anyone curious about the future of longevity and healing. Chapters: 0:00 – Introduction & sponsor message 2:37 – Meet Dr. Jeff Gross 4:18 – From surgery to regenerative medicine 12:43 – What exactly is a peptide? 22:22 – Types of stem cells and what's legal in the U.S. 25:56 – Stem cells and Parkinson's treatment 28:22 – Cartilage regeneration and joint pain 31:14 – Finding a trustworthy regenerative medicine clinic 35:23 – Mitochondrial peptides (SS-31, MOTS-C) 41:15 – Where to find Recelebrate Show Sponsor: Jason Gagne's Good2GoBody 90-day beginner fitness program - https://good2go.podia.com/?coupon=LIONSJOHN Links: Learn more: https://recellebrate.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices
The FDA advisory committee voted July 23rd and 24th and social media has been running wild with the news, but most of what's circulating about BPC 157 and the other peptides that were on the agenda is either half-right or completely wrong. Inside today's episode, I break down what happened at the FDA's Widow campus in Silver Spring, what the 8 to 6 to 1 vote on BPC 157 means, and how to think about the timeline for legal access over the next 12 to 24 months. walk through the category one, two, and three interim policy that determines whether the FDA will take enforcement action during the rule making window, and more.Topics discussed: - The July FDA Advisory Committee Vote- The Seven Peptides on the Agenda- FDA Review Staff vs the Committee- The Research-to-Real-Use Mismatch- Section 503A and the Bulks List- Category One vs Category Two Policy- The 12 to 24 Month Access Timeline- State Medical Boards and Enforcement- What This Means for Health Coaches---------- My Live Program for Coaches: The Functional Nutrition and Metabolism Specialization www.metabolismschool.com---------- [Free] Metabolism School 101: Video Serieshttp://www.metabolismschool.com/metabolism-101----------Subscribe to Youtube Channel: https://youtube.com/@sammillerscience?si=s1jcR6Im4GDHbw_1----------Grab a Copy of My Book - Metabolism Made Simple---------- Stay Connected: Instagram: @sammillerscienceYoutube: SamMillerScience Facebook: The Nutrition Coaching Collaborative CommunityTikTok: @sammillerscience----------“This Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast and the show notes or the reliance on the information provided is to be done at the user's own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment and is for educational purposes only. Always consult your physician before beginning any exercise program and users should not disregard, or delay in obtaining, medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. By accessing this Podcast, the listener acknowledges that the entire contents and design of this Podcast, are the property of Oracle Athletic Science LLC, or used by Oracle Athletic Science LLC with permission, and are protected under U.S. and international copyright and trademark laws. Except as otherwise provided herein, users of this Podcast may save and use information contained in the Podcast only for personal or other non-commercial, educational purposes. No other use, including, without limitation, reproduction, retransmission or editing, of this Podcast may be made without the prior written permission of Oracle Athletic Science LLC, which may be requested by contacting the Oracle Athletic Science LLC by email at operations@sammillerscience.com. By accessing this Podcast, the listener acknowledges that Oracle Athletic Science LLC makes no warranty, guarantee, or representation as to the accuracy or sufficiency of the information featured in this Podcast."
Nvidia is in talks with OpenAI to finance a new data center project in Ohio, according to reports. As markets kick off the busiest week of earnings season, investor Steve Eisman shares his perspective on the AI trade, big tech's big capital expenditures, the moats around tech and AI companies, and how he's hedging his own portfolio. CNBC's Dan Murphy reports on the current pause in fighting between the U.S. and Iran, and RBC Capital Markets' Helima Croft discusses the conflict's impact on the energy markets. Plus, PharmatrophiX co-founder and Stanford Professor Dr. Frank Longo explains Compound 31, a new FDA-approved drug to treat Alzheimer's. He shares his personal journey toward medical innovation in the field, and shares the differentiators between Compound 31 and the Alzheimer's treatments that have come before it. Dan Murphy - 07:50 Helima Croft - 12:43 Steve Eisman - 22:36 Dr. Frank Longo - 34:43 In this episode: Joe Kernen, @JoeSquawk Becky Quick, @BeckyQuick Dan Murphy, @dan_murphy Katie Kramer, @Kramer_Katie Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Taylor Farms got the apology it wanted. The FDA told the company that one iceberg lettuce product from Central Mexico had a “confirmed positive” cyclospora test, then said the next day it had made a mistake and the result was a false positive. As of the FDA's own account, no positive product test for cyclospora has been identified. Taylor Farms then built an entire statement around that apology, led with it, and left the people who got sick in the last paragraph under "our thoughts remain."That is where this crisis got away from them. A false positive on one test does not mean the outbreak isn't yours — and as I say on the live, it is still unclear exactly where this outbreak is coming from. The FDA's traceback pointed at Central Mexico. And while Taylor Farms spent its statement arguing with a federal agency, the story became a Taco Bell story. Muck Rack ran the numbers for the live and you can watch it happen: Taco Bell's article volume runs past everyone else's, Taco Bell turns up inside the Taylor Farms word cloud, then inside the Walmart word cloud. Taco Bell started promoting menu items without lettuce. Taylor Farms took its statement down entirely.In this breakdown I read the statement line by line, ask who was in the room while it was written, and show you what the media data did before and after the correction. You always have to speak to the pain. You don't have to describe the symptoms, but you do have to see the person who ate that salad at a party, on vacation, at a rehearsal dinner.Second half: Amy Griffin, her memoir The Tell, and a lawsuit from a former classmate who says the book's most harrowing anecdotes came from her life. Griffin's answer was to file her own suit and pull the New York Times into it. Same week, same playbook as Taylor Farms. Attack the institution, skip the harm. The biggest tell that your story doesn't hold up is when you attack the press.Chapters:0:00 The Friday hit list and this week's PR fires1:12 Where the Taylor Farms PR goes off course1:58 The full Taylor Farms statement, read line by line3:15 The headline is a request to be vindicated4:12 Company versus agency is never the play5:12 "Our thoughts remain" and who was in the room6:43 The fatal flaw, it forgets the pain8:00 The statement gets pulled, and the audience word cloud9:37 Taco Bell takes the hit, the Muck Rack numbers10:57 Word clouds for FDA, Taco Bell, Taylor Farms and Walmart12:26 What a false positive actually means, and the sentiment swing14:42 A question about FDA quality control15:30 Amy Griffin, The Tell, and why I stopped reading16:46 Who actually sells books now18:43 Bell Burden, Martha's Vineyard, and hidden wealth20:07 The classmate's lawsuit21:22 What bad PR looks like in the New York Times23:23 Maureen Callahan and the media industrial complex24:23 Attacking the press is the tell25:00 The legal-threat play26:29 Same playbook, both stories27:46 Mitch McConnell watch28:37 September category trainings
In this episode, Dr. Linda Bosserman shares her expertise on hormone therapy, addressing common misconceptions and highlighting the latest science supporting their safe use in women and men. Tune in to hear practical insights on hormone management, systemic and local applications, and how to advocate for your health.Key Topics Covered:The importance of precise language: specifying hormone types, routes, and dosesThe safety and efficacy of vaginal estrogen in women with breast cancerDebunking myths about hormones causing breast cancer: data from large studiesThe potential of testosterone in improving neurocognition, libido, and overall health in womenThe ongoing fight for FDA approval of female testosterone productsThe role of systemic hormones in preventing cardiovascular diseaseHow to counsel patients on hormone-related recurrence risksThe significance of personalized, evidence-based hormone therapy for optimal agingInsights from Dr. Bosserman's PhD in sex therapy and its relevance to sexual healthThe systemic biases and misinformation perpetuated by media and outdated guidelinesDr. BossermanMenopausal Hormone Therapy after Breast CancerSubscribe, leave a review, and share this episode with someone who needs it.
Artificial Sweeteners & Cognitive Decline, Myosteatosis on Coronary CT, Merck's Oral PCSK9 Inhibitor, Cyclospora Outbreak, Gut-Brain Synchronization, and the Banana Smoothie Mistake Explained Artificial Sweeteners Linked To 62% Faster Cognitive Decline In Landmark Brazilian Study A study tracking more than 12,700 adults (average age 52) over eight years found that people consuming the most artificial and low-calorie sweeteners, roughly 191 mg a day, about what's in a single can of diet soda, showed cognitive decline 62% faster than the lowest-intake group, equivalent to 1.6 extra years of brain aging, with memory hit hardest. Six of the seven sweeteners tested, including aspartame, saccharin, and acesulfame K, were linked to faster decline; tagatose was the lone exception. Researchers point to gut-microbiome disruption, altered glucose and insulin signaling, and possible direct neuronal effects as plausible mechanisms. Host Dave Asprey breaks down why a dose this small was enough to move the curve, why tagatose deserves more scrutiny before being called "safe," and where diet products' short-term weight-loss marketing conveniently ignores the long-term cost to your brain. Source: https://www.inc.com/kevin-haynes/study-links-cognitive-decline-to-surprisingly-small-daily-amount-of-artificial-sweeteners/91376522 ~~ AI Analysis Of 1,722 Heart Scans Finds Muscle Quality Predicts Heart Attacks Independent Of Calcium Score Using data from the SCOT-HEART trial, a University of Edinburgh team ran an AI model against ten years of coronary CT angiogram scans, measuring skeletal muscle attenuation, a marker of myosteatosis, or fat infiltration into muscle tissue. Every 10-point increase in muscle density corresponded to a 31% lower heart attack risk and 39% lower all-cause mortality over the following decade, and critically, this held independent of coronary calcium score, the current gold-standard risk marker. The same low-density-muscle patients also showed higher lung attenuation, lower liver attenuation, and more torso fat volume, a pattern consistent with systemic insulin resistance rather than a muscle-specific issue. Host Dave Asprey unpacks why calcium score isn't capturing the full risk picture, why myosteatosis is really a readout of whole-body insulin sensitivity, and what he'd add to a routine workup on top of a calcium score. Source: https://www.theguardian.com/science/2026/jun/30/strong-chest-back-less-likely-heart-attack-analysis ~~ FDA Approves First Oral PCSK9 Inhibitor, Cutting LDL By Up To 60% Without Injections Merck's enlicitide (brand name Lipfendra) is now FDA-approved as the first once-daily oral PCSK9 inhibitor, lowering LDL cholesterol by up to 60% in a phase 3 trial of 2,912 patients, routinely bringing levels down to 50-60 mg/dL. It works by blocking PCSK9, a liver protein that tags LDL receptors for destruction, the same target as injectable drugs like Repatha and Praluent, which have shown roughly 20% reductions in heart attacks and strokes in high-risk patients. Lipfendra is priced at $315 for a 30-day supply, with no excess side effects reported versus placebo over six months, though long-term outcome data is still pending. Host Dave Asprey explains why crushing total LDL without checking ApoB, LDL particle number, or oxidized LDL is optimizing the wrong variable, and what he'd want on his labs before considering a drug like this. Sources: https://www.nytimes.com/2026/07/16/science/the-fda-approves-a-new-pill-to-slash-cholesterol-levels.html https://www.cnbc.com/2026/07/16/mercks-cholesterol-pill-gets-us-fda-approval.html ~~ Cyclospora Outbreak Tied To Taylor Farms Lettuce Spreads To 34 States, Prompts Nationwide Recall Federal investigators have linked a multistate cyclosporiasis outbreak to shredded iceberg lettuce from Taylor Farms de Mexico, with Michigan alone logging over 5,000 cases and 100+ hospitalizations, much of it traced to lettuce used at Taco Bell. Taylor Farms has recalled all iceberg lettuce sourced from central Mexico, and Walmart has pulled Marketside Iceberg Salad and Marketside Shredded Lettuce with specific date codes across 27 states. Cyclospora spreads through fecal contamination and causes weeks of watery, explosive diarrhea if untreated; washing doesn't reliably eliminate it, since the parasite requires heat above 158°F to inactivate. Host Dave Asprey explains why pre-washed, pre-cut bagged greens remain a recurring contamination risk no matter what the label claims, and connects the outbreak's gut damage to lingering gut-brain consequences long after symptoms resolve. Sources: https://www.usatoday.com/story/news/health/2026/07/18/taylor-farms-shredded-lettuce-sample-cyclospora/90969103007/ https://www.fda.gov/food/outbreaks-foodborne-illness/investigation-5-state-outbreak-cyclospora-illnesses-iceberg-lettuce-july-2026 ~~ New Research Links Excessive Gut-Brain Synchronization To Anxiety And Depression Emerging research on the enteric nervous system, which contains over 100 million neurons and sends more signals to the brain than it receives, finds that when the gut's electrical rhythm synchronizes too tightly with the brain's, that over-coupling correlates with higher rates of anxiety and depression. The gut communicates with the brain through the vagus nerve, hormones, and immune signaling, and dysbiosis or ENS dysfunction has separately been linked to mood disorders in both human and animal studies. Host Dave Asprey breaks down why the goal isn't maximum gut-brain connection but the right kind of connection, questions whether the coupling is driving the anxiety or the anxiety is driving the coupling, and makes the case for treating mood from the gut up instead of the brain down. Source: https://refractor.io/medical/enteric-nervous-system-brain-link-mental-health/ ~~ Rhonda Patrick Explains Why She Never Adds Bananas To Her Berry Smoothies Rhonda Patrick has been telling audiences she skips bananas in her berry smoothies because of polyphenol oxidase, an enzyme in bananas that degrades the polyphenols in blueberries linked to improved cognition and vascular health, based on in-vitro and food chemistry data. She now builds her smoothies on an avocado base instead, and notes that vitamin C from citrus can partially inhibit the enzyme for anyone unwilling to drop the banana. Host Dave Asprey weighs in on the gap between lab chemistry and clinical outcome data, why that gap doesn't make the mechanism any less real, and why this is a low-cost swap worth making even without a human trial behind it. Sources: https://www.reddit.com/r/Biohackers/comments/1v2jbib/dr_rhonda_patrick_i_dont_add_bananas_to_my/ https://www.foundmyfitness.com/episodes/polyphenol-oxidase-bananas-smoothies ~~ This episode is designed for biohackers, longevity enthusiasts, and high-performance listeners who want mechanism-level insight into a sweetener risk hiding in everyday diet products, a heart attack predictor buried inside routine CT scans, the tradeoffs of a new cholesterol drug, a produce recall worth paying attention to, the science behind gut-driven anxiety, and a smoothie mistake that's quietly undercutting your polyphenol intake. Host Dave Asprey connects clinical research, cohort data, and food chemistry into practical frameworks for protecting brain health, cardiovascular health, and gut-brain resilience. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: artificial sweeteners cognitive decline, aspartame brain aging, tagatose safety, diet soda memory loss, myosteatosis coronary CT, skeletal muscle attenuation heart attack, SCOT-HEART trial, coronary calcium score insulin resistance, enlicitide Lipfendra FDA approval, oral PCSK9 inhibitor, LDL particle number ApoB, cyclospora outbreak 2026, Taylor Farms lettuce recall, cyclosporiasis symptoms treatment, enteric nervous system anxiety, gut brain synchronization, vagus nerve mental health, Rhonda Patrick polyphenol oxidase, banana blueberry smoothie mistake, biohacking news 2026, Dave Asprey, The Human Upgrade Thank you to our sponsors! - Suppgrade Labs | Get real restorative sleep with Quiet Mode. Use code DAVE15 at shopsuppgradelabs.com. - EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:19 – Story 1: Artificial Sweeteners 02:05 – Story 2: Muscle Fat & Heart Risk 04:36 – Story 3: PCSK9 Cholesterol Pill 06:27 – Story 4: Cyclospora Lettuce Outbreak 07:56 – Story 5; Gut-Brain Axis & Anxiety 09:29 – Story 6: Banana vs. Blueberry 11:08 – Predictions for Next 5 Years See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
P.M. Edition for July 24. Today an FDA committee voted to increase access to six of seven peptides. Those are substances that haven't undergone regulatory approval, but they're promoted on social media and promise physical transformations like better skin. We hear from WSJ health and wellness reporter Alex Janin about what the vote means and whether it paves the way for a peptide gold rush. Plus, new tariffs went into effect today intended to combat forced labor, and President Trump also threatened new tariffs on the European Union. Journal trade and economic policy reporter Gavin Bade discusses the future of President Trump's tariff agenda. And measles cases in the U.S. this year have already surpassed last year's number, reaching a three-decade high. Alex Ossola hosts. And for more on peptides, listen to our What's News Sunday episode. Sign up for the WSJ's free What's News newsletter. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
By now, you've probably heard more than you ever wanted about cyclospora, a parasite that spreads via infected water and food and causes explosive diarrhea. This has been a very bad year for cyclosporiasis. According to the New York Times, the Centers for Disease Control and Prevention typically report an average of 2,800 cases of the illness in the U.S. every year. But this year, the CDC reports more than 11,000 cases across 41 states. So, for more on our summer of cyclosporiasis and why you should maybe skip the bagged lettuce, we spoke to Julie Rovner. She's the Chief Washington correspondent and host of the "What the Health?" podcast at KFF Health News.And in headlines, Yemen's Iran-backed Houthi rebels claim attacks on two Saudi oil tankers in the Red Sea, Ukrainian drones are targeting Russia's largest online marketplace, and the FDA reviews seven peptide injections the agency banned three years ago over safety concerns.Show Notes: Check out What The Health? – kffhealthnews.org/podcast-series/what-the-health/ Call Congress – 202-224-3121 Subscribe to the What A Day Newsletter – https://tinyurl.com/y4y2e9jy What A Day – YouTube – https://www.youtube.com/@whatadaypodcast Follow us on Instagram – https://www.instagram.com/crookedmedia/ For a transcript of this episode, please email transcripts@crooked.com
The cyclospora outbreak that's sickening thousands of Americans got us interested in the rise of Big Lettuce, and the challenges of keeping it clean. So on today's show, we tell you just how much lettuce Americans eat every year (SO MUCH!), how bagged lettuce came to dominate grocery store shelves, what that means for food safety, and why these outbreaks continue to happen — despite the FDA's efforts to stop them.Check out other related episodes:Food Scare SquadHow refrigeration took over the worldSupport:Planet Money+Read: Our book: Planet Money: A Guide to the Economic Forces That Shape Your Life Our weekly longform Planet Money newsletterOur weekly Indicator round-up newsletterFollow: InstagramTikTokYouTubeFacebookThis episode was hosted by Jeff Guo and Emma Peaslee. It was produced by Emma Peaslee. It was edited by Marianne McCune and it was fact checked by Sierra Juarez and engineered by Annlie Huang. Alex Goldmark is Planet Money's executive producer. Music: NPR Source Audio - "Electric Leak," "West Green Road," and "Melty Heart"See pcm.adswizz.com for information about our collection and use of personal data for sponsorship and to manage your podcast sponsorship preferences.NPR Privacy Policy
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