Podcasts about fda

Agency of the United States Department of Health and Human Services

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    Conservative Daily Podcast
    Joe Oltmann Untamed | Dr. Paul Alexander | The Siege of Psyche | 04.27.26

    Conservative Daily Podcast

    Play Episode Listen Later Apr 27, 2026 98:15


    This episode pulls no punches as we dissect the coordinated mental warfare campaign currently being waged against the American people. From the explosive frustration of Joe Hoft shredding Christopher Wray and William Barr for their alleged roles in covering up election fraud in Michigan and Georgia, to the chilling reality of the recent White House Correspondents' Dinner shooting, we explore a nation divided by two irreconcilable versions of reality. We examine the "Siege of the Psyche" a 24/7 indoctrination effort through media and influencers designed to gaslight citizens, suppress the truth about voter ID and the SAVE Act, and dehumanize conservatives to the point where political violence is not only predictable but celebrated by the radical left.We are joined by Dr. Paul Alexander, a former HHS Senior Advisor and renowned epidemiologist, to break down his bombshell analysis of the WHCD incident. Dr. Alexander questions whether the security lapses that put President Trump at risk were intentional, raising the specter of internal sabotage and modern MKUltra-style tactics. The conversation dives deep into the "enemy within" the current administration, the suppression of early COVID treatments, and the absolute lack of accountability for agencies like the CDC and FDA. We confront the dangerous rhetoric from figures like Jimmy Kimmel and Governor J.B. Pritzker, whose "Nazi" branding of the right serves as a psychological green light for the domestic terrorism we are seeing unfold in real-time.As the left continues to signal acceptance for violence exemplified by the appalling reactions to the assassination attempt on Donald Trump and the tragic death of Charlie Kirk—we ask: how can a country function when one side believes they have the moral authority to eliminate their neighbors? From the "lawfare" being played out in Michigan ballot access battles to the radicalization of youth through leaders who openly call for "choking out" their opponents, this episode is a clarion call for awareness. Watch now to understand the mechanics of this mental war and why the current trajectory of state-sponsored gaslighting is leading America toward an inevitable and dangerous breaking point.

    Your Parenting Mojo - Respectful, research-based parenting ideas to help kids thrive
    264: Who Really Decided Your Child Needs ADHD Medication?

    Your Parenting Mojo - Respectful, research-based parenting ideas to help kids thrive

    Play Episode Listen Later Apr 27, 2026 45:20 Transcription Available


    If your child has been diagnosed with ADHD, stimulant medication is probably the first thing their doctor mentioned. And if you're trying to figure out whether it's the right choice for your family, you deserve more than a pamphlet published by a drug company. You deserve the full picture - including what the research really shows, who funded it, and the questions the medical model of ADHD hasn't answered. The story most parents get is a tidy one: ADHD is a chronic brain disorder, it's highly heritable, and stimulant medication is the most effective treatment. That story comes mostly from one very influential researcher, Dr. Russell Barkley, and it has shaped how millions of families make medication decisions.  But when you look closely, cracks start to appear - in the diagnostic criteria, in the science, and in the financial ties between the researchers who built the medical model and the pharmaceutical companies that profit from it. Questions this episode will answer What are the DSM-5 criteria for diagnosing ADHD? The DSM-5 requires children to show at least 6 symptoms (5 for adults) that appear "often" across multiple settings. But who decides how often is "often" - and whether a behavior is "inappropriate" - turns out to be deeply shaped by cultural values, not objective measurement. Why are ADHD diagnoses increasing? Research shows that school accountability policies like No Child Left Behind drove significant increases in ADHD diagnoses, particularly among low-income children. In some states, diagnosing a child with ADHD could raise a school's average test scores - creating a financial incentive that had nothing to do with the child's actual needs. What is Russell Barkley's theory of ADHD? Barkley sees ADHD as a chronic, highly heritable brain disorder rooted in deficits in executive functioning. He compares it to diabetes: a lifelong condition requiring ongoing treatment, primarily with stimulant medication. This episode examines both his framework and the places where his own research contradicts itself. Is ADHD overdiagnosed? The evidence suggests yes, in many cases. Diagnosis rates vary by a factor of two to three across U.S. states when there aren't consistent biological or cultural differences between these states. Many children receive a diagnosis after a 15-minute pediatric visit, not the thorough multi-source evaluation the research actually recommends. Is ADHD neurodivergent? Yes - and that framing shapes how a child with ADHD gets supported. The medical model treats ADHD as a brain disorder: something broken that medication needs to fix. A neuroaffirming approach treats it as a difference - and asks whether the environment, not just the child, needs to change. The diagnostic criteria themselves embed specific cultural values about what counts as "appropriate" behavior. Whether your child gets treated as disordered or different depends entirely on which framework their clinician is working from. What is actually happening in an ADHD brain? Barkley frames ADHD as a deficit in executive functioning - the brain systems that regulate attention, impulse control, and behavior over time. But the research on whether stimulant medication repairs that brain development is contradictory, and Barkley himself makes both claims in different videos. What are the benefits of ADHD medication? Stimulant medication does improve attention and reduce motor activity in the short term - but it does this in everyone's brain, not just in people with ADHD. This episode looks at what medication actually does, what it doesn't do, and what the drug company advertising left out. What you'll learn in this episode Why the word "often" in every single DSM-5 ADHD criterion creates a diagnosis that depends heavily on who is observing the child - and what cultural standards they're applyingHow the same behaviors in children in Hong Kong were rated far more severely than those of children in the U.K., and what that tells us about what ADHD is actually measuringThe financial relationships between the most influential ADHD researchers - including Barkley and Dr. Joseph Biederman - and the pharmaceutical companies that make ADHD medicationsWhy ADHD diagnosis rates in states like North Carolina and Ohio run two to three times higher than in California and Nevada, and what school accountability policies have to do with itThe contradiction at the heart of Barkley's medical model: if stimulant medication promotes brain development, why does he say it must be taken for life?How drug company ads used Barkley's and Biederman's research to frighten parents into medicating their children - and the FDA's ineffective responseWhy the scary outcome statistics Barkley cites - including a reduced life expectancy of up to 13 years - don't tell us much about outcomes for real people with ADHDWhat a neuroaffirming approach to ADHD looks like, and why this episode argues that the most important question isn't how to change the child to fit the environment - it's whether the environment fits the child Click here to download the infographic: What You've Been Told About ADHD vs. What the Research Actually Shows Jump to highlights: 01:14 Jen introduces a three-episode arc examining the medical model of ADHD, which positions it as a chronic, highly heritable brain disorder. This first episode covers what ADHD is according to leading researcher Dr. Russell Barkley, how it's diagnosed, problems with diagnosis, and financial conflicts of interest. 06:37 Kids need six out of nine symptoms, adults need five. Each symptom must occur "often" - but there's no objective measure for what "often" means. 10:10 Dr. Barkley sees ADHD as a deficit in executive functioning - the ability to self-regulate over time. It breaks down into inhibition (hyperactive-impulsive behavior) and metacognition (inattention symptoms, which he says are misnamed). 12:37 Dr. Barkley compares ADHD to diabetes, saying it's a chronic condition needing ongoing treatment. Just like you wouldn't expect insulin to cure diabetes, he argues, you shouldn't expect ADHD medication to fix someone's brain so they can stop taking it. 23:30 Barkley says parents might have legitimate reasons for "non-compliance" with training, like family stress. Training may be discontinued while stress is managed. But kids who don't comply get behavior modification - no understanding or flexibility for them. 30:45 Barkley has essentially created a new diagnostic category called Sluggish Cognitive Tempo (marked by daydreaming, lethargy, slowed thinking) even though it's never been recognized by the Psychiatric Association. 35:44 Barkley presents data showing males with ADHD have a life expectancy 6.8 years less than the general population, females 8.6 years less. That's on par with smoking. Outcomes include lower education and income, more substance use, higher suicide rates (three times higher), more accidents, higher obesity and diabetes rates, and higher cardiovascular disease. 43:01 Wrapping up the discussion

    Vitality Radio Podcast with Jared St. Clair
    #633: Beyond Collagen: Elastin, Keratin & the Real Anti-Aging Strategy

    Vitality Radio Podcast with Jared St. Clair

    Play Episode Listen Later Apr 25, 2026 42:22


    On this episode of Vitality Radio, Jared sits down with Jodi Sanders, National Educator for BioSil, to explore the science behind collagen production and why supporting your body's natural processes may be more effective than simply supplementing collagen alone. They break down the critical roles of collagen, elastin, and keratin in maintaining healthy hair, skin, nails, joints, and connective tissue—and why production declines with age. You'll learn how BioSil's patented choline-stabilized orthosilicic acid (CHOSA) is designed to support the body's natural collagen-building pathways, along with insights into lifestyle factors that impact these structural proteins. The conversation also introduces a new, highly digestible plant-based protein designed to deliver a complete amino acid profile. If you're looking to support healthy aging, structural integrity, and overall vitality, this episode delivers practical, science-backed insights.Products:Biosil Advanced Collagen GeneratorBiosil Daily Beauty ProteinAdditional Information:#542: VR Vintage: Your Collagen User's Guide: How to Preserve and Build Collagen NaturallyVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

    Infertile AF
    Do You Need a Plastic Detox? Breaking Down How Everyday Household Items May Be Affecting Your Fertility with Dr. Shanna Swan

    Infertile AF

    Play Episode Listen Later Apr 24, 2026 23:02 Transcription Available


    What if the products you use every single day—your water bottle, your skincare, your food containers—are quietly impacting your fertility? In this episode, Ali dives into The Plastic Detox on Netflix—the documentary that has everyone questioning what's in their homes (and their bodies). Ali is joined by Dr. Shanna Swan, one of the world's leading researchers on environmental exposures and reproductive health—and a featured expert in the film. Ali and Dr. Swan talk about how the doc came to be, the real link between plastics, chemicals, and fertility, and how you can make realistic, non-overwhelming changes in your daily life. EPISODE SPONSORS: THE WORK OF ART BOOK SERIESAli's Children's Book Series about IVF, IUI and Family Building Through Assisted Reproductive Technology https://www.infertileafgroup.com/booksThe 3-book bundle is now just $49 (normally $79)!The latest book in the Work of ART series, “You Are a Work of ART," is for every kiddo born through ART -- and the people who love them.PHERDALIG: @pherdal_sciencePherDal is the world's first and only FDA-cleared, sterile, at-home insemination kit designed to help people build their families in the comfort of home. Created by parents who've been there, PherDal is safe, simple, and affordable—putting more options in your hands as you grow your family. Explore at PherDal.com.Go to PherDal.com today and use code INFERTILEAF for $10 off.BELIIG: @belibabywww.belibaby.com Are you thinking about growing your family? Whether you're just starting to plan or are actively trying to conceive, preconception health is key. Beli has vitamins to help both women and men optimize their health before pregnancy. With essential nutrients like Folate, Iodine, and Zinc, Beli ensures your body is ready for this exciting next step. Give yourself and your future baby the best foundation for a healthy start.Visit Belibaby.com today and use code IAF15 for 15% off your first order. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

    PBS NewsHour - Segments
    News Wrap: DOJ drops criminal probe into Jerome Powell

    PBS NewsHour - Segments

    Play Episode Listen Later Apr 24, 2026 5:04


    In our news wrap Friday, the Justice Department is dropping its criminal probe into Federal Reserve Chair Jerome Powell, a federal appeals court ruled that President Trump's executive order banning asylum claims at the U.S. southern border is illegal and the FDA said it will fast-track reviews for three psychedelic drugs aimed at treating mental health conditions. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

    MAPS Podcast
    Episode 15 - Dr. Joe Tafur: His Medicine Song

    MAPS Podcast

    Play Episode Listen Later Apr 24, 2026 67:18


    Episode 15 - Dr. Joe Tafur: His Medicine Song Dr. Joe Tafur returns to the podcast to talk about his fantastic new book "Medicine Song: Spiritual Healing and The Psychedelic Renaissance." This conversation, like Joe's book, is a personal glimpse into his very unique perspective on shamanic medicines through the lens of a western doctor that has been transformed into something new entirely. To say that Joe is any one thing is short sighted. Joe embodies the best standards and practices of ceremonial use but delivers it in a way that is humble, approachable and so full of wisdom.  Intro: a recap on the questions we need to ask ourselves in the face of Trump's exeuctive order fast tracking FDA approval for psychedelic medicines.  This episode is sponsored by Amentara Ethnobotanicals - https://www.amentara.com/ www.zachleary.net https://www.drjoetafur.com/ www.psychedelicstoday.com  

    Squawk Pod
    David Sacks, Anthropic, & the White House, Regeneron's Deafness Cure 4/24/26

    Squawk Pod

    Play Episode Listen Later Apr 24, 2026 38:23


    The FDA has approved Regeneron's gene therapy for a rare form of inherited deafness, and it's free for Americans. Regeneron CEO Leonard Schleifer discusses the breakthrough treatment, drug pricing, AI's role in medical innovation, and what breakthroughs might come next. Co-chair of the President's Council of Advisors on Science and Technology David Sacks was one of the original executives at PayPal, alongside Elon Musk and Peter Thiel. As an AI and crypto advisor to President Trump, the All In Podcast co-host is helping shape AI regulation and policy in the United States. He comments on the government's complicated relationship with Anthropic and the ongoing feud between Elon Musk and Sam Altman. Plus, a U.S. soldier was arrested for his winning Polymarket bet on the capture of Venezuelan leader Nicolás Maduro, and Intel reported a blowout quarter.   David Sacks - 17:43 Leonard Schleifer - 29:21   In this episode: Becky Quick, @BeckyQuick Joe Kernen, @JoeSquawk Andrew Ross Sorkin, @andrewrsorkin Katie Kramer, @Kramer_Katie Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    Dr. Chapa’s Clinical Pearls.
    DIY PPH Tools: FOCUS, STUT, and/or U-CaVIT

    Dr. Chapa’s Clinical Pearls.

    Play Episode Listen Later Apr 23, 2026 26:45


    Uterine hemorrhage remains a significant complication following abortion loss and in the postpartum period and contributes to substantial morbidity and mortality among pregnant patients. Although some FDA approved devices are on the market (Bakri balloon and Jada vacuum), they may be cost prohibited in some settings and/or some uterine cavities may be very small for either option, like after a mid-second trimester or early third trimester PPH. But every delivery unit has some form of suction tool and wall suction ability. This is where FOCUS*, STUT, and/or U-CaVIT come into play. And now there is new data on this from the AJOG (epub, April 2026). Listen in for details. (*Shout Out to Dr. Frank Jackson for his work on this as well).1. Singata-Madliki et al. Suction Tube Uterine Tamponade Versus Uterine Balloon Tamponade for Treatment of Refractory Postpartum Hemorrhage: A Randomized Clinical Feasibility Trial. International Journal of Gynaecology and Obstetrics: The Official Organ of FIGO. July 2025. (South Africa)2. Hofmeyr GJ, Singata-Madliki M. Novel Suction Tube Uterine Tamponade for Treating Intractable Postpartum Haemorrhage: Description of Technique and Report of Three Cases. BJOG : An International Journal of Obstetrics and Gynaecology. 20203. Jackson FI, Dilena NJ, Abelman SH, Blitz MJ, Gerber S. Hemorrhage management using a Foley catheter for uterine suction. Am J Obstet Gynecol. 2025 Nov;233(5):503-504. 4. ACOG Practice Bulletin No. 183: Postpartum Hemorrhage. Obstetrics and Gynecology. 2017. 5. Ranieri E, Kalimeris S, Ochsenbein N, Haslinger C, Vacuum-Induced Tamponade Using Urological Catheters for Postpartum Hemorrhage, American Journal of Obstetrics and Gynecology (2026), doi: https://doi.org/10.1016/j.ajog.2026.04.026

    Breaking Beauty Podcast
    #DamnGood Foundations Guide! Why Armani, NARS & Estée Lauder Re-Formulated (and Our New Faves to Buy ASAP)

    Breaking Beauty Podcast

    Play Episode Listen Later Apr 22, 2026 57:32


    It's 2026 and everyone's asking: why has my Holy Grail foundation been reformulated?! We're explaining the reason behind the industry-wide shakeup this week. From a $16.99 drugstore dupe to a luxury splurge at $145 — we're uncovering what's #DamnGood now in the next-gen foundation landscape. What you'll learn in this episode: Why major foundation brands — including Armani, Estée Lauder and NARS — have been forced to reformulate their most iconic productsHow the removal of cyclopentasiloxane has changed the texture, wear and shade ranges of cult classicsWhat the serum foundation trend means for your skin — and which new ones break through with their performanceWhich nouveau matte formulas are worth trying if you're oily-skinned — and which ones to skipWhether luxury foundations justify their price tags (including one at $145 US) For any products or links mentioned in this episode, check out our website: https://breakingbeautypodcast.com/episode-recaps/ Get social with us and let us know what you think of the episode! Find us on Instagram, Tiktok,X, Threads. Join our private Facebook group. Or give us a call and leave us a voicemail at 1-844-227-0302. Sign up for our Substack here. Subscribe to our YouTube Channel to watch our episodes! Related episodes like this: Are You Applying Your Foundation The Right Way? How-to Find the Perfect Shade, Formula, Layering Tips and More With Beyonce's Makeup Artist Sir John

    Public Health On Call
    1040 - Growing Demand for Menopausal Hormone Therapies Brings Excitement—and New Concerns

    Public Health On Call

    Play Episode Listen Later Apr 22, 2026 18:49


    About this episode: Following the FDA's removal of black box warnings for hormone therapy drugs, demand has skyrocketed for menopause treatments. In this episode: why this explosion in popularity marks a trend in the right direction for quality reproductive care while also raising concerns about "menowashed" products and blanket prescribing of hormonal interventions. Guests: Dr. Wendy L. Bennett, MPH, is a primary care doctor and associate professor with appointments at the Johns Hopkins Bloomberg School of Public Health and School of Medicine. Dr. Tina Zhang is a primary care doctor and assistant professor at the Johns Hopkins University School of Medicine. Host: Stephanie Desmon, MA, is a former journalist, author, and the director of public relations and communications for the Johns Hopkins Center for Communication Programs. Show links and related content: Why the 'mad scramble' to fill hormone therapy prescriptions for menopause—NPR FACT SHEET: FDA Initiates Removal of "Black Box" Warnings from Menopausal Hormone Replacement Therapy Products—U.S. Department of Health and Human Services What Is a Black Box Warning?—Johns Hopkins Bloomberg School of Public Health De-medicalizing Menopause—Public Health On Call (March 2024) Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @‌PublicHealthPod on Bluesky @‌PublicHealthPod on Instagram @‌JohnsHopkinsSPH on Facebook @‌PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.

    Me & Paranormal You
    VOYAGE 028 | Interpretation of Worlds and The Transmutation Oracle Deck with Nikoo Bafti

    Me & Paranormal You

    Play Episode Listen Later Apr 22, 2026 74:32


    Artist, Mystic and all-around interpreter of worlds, Nikoo Bafti joins me to discuss the launch of The Transmutation Oracle Deck that she hand-crafted for the Philosophical Research Society. They have not made a tarot deck in over 100 years until they reached out to her. Wowsers. We get into the journey and her radical shift as an artist and what all people experience in form or another, as we navigate and try to interpret the world and magic around us. How does that unfold and what form does it take for you? We have a wonderful discussion about all things mystical and then get a sneak peek at The Transmutation Oracle she created in collaboration with writer Laura Hayes. More on the deck: The Transmutation Oracle Deck is here to serve as a guide, a navigational tool that helps you to engage with the world under the assumption that reality is holographic and far more malleable than we have been taught. Humans have far more agency than most of us believe, and this deck provides fun ways to interact with and influence reality, whilst also encouraging a deeper understanding of the interconnectedness of all things. The universe speaks in symbols and you can learn to read and respond to it. Sunday May 3rd see Nikoo's presentation at PRS by clicking here! Find the deck here! Nikoo's website here! Nikoo's Instagram here! Nikoo Bafti is a British-Iranian Visual Artist and Illustrator. After graduating with a BA (Hons) in Illustration & FdA in Visual Communication from the Arts University of Bournemouth, Nikoo began her career as an Animation Development Intern at Disney Channels in London and has since established her own freelance practice as an Illustrator and Visual Artist exhibiting internationally. Her clients include The Philosophical Research Society, Psychic Garden, Disney Channel & Truly Hard Seltzer. Nikoo's work takes a look behind a thinning veil to a realm of the mystical and anomalous through her intensely saturated and arresting colour palettes. Her use of fine detail and delicate, emblematic markings are reminiscent of the traditional Persian Miniature painting style of her heritage. You can find more on my stand-up schedule, short films and more at: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://ryansingercomedy.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Commercial Free episodes here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ SpectreVision Radio is a bespoke podcast network at the intersection between the arts and the uncanny, featuring a tapestry of shows exploring creativity, the esoteric, and the unknown. We're a community for creators and fans vibrating around common curiosities, shared interests and persistent passions. Learn more about your ad choices. Visit megaphone.fm/adchoices

    Vitality Radio Podcast with Jared St. Clair
    #632: The Vitality Verdict: Beyond the Headlines - The Ozempic (GLP-1) Economy

    Vitality Radio Podcast with Jared St. Clair

    Play Episode Listen Later Apr 22, 2026 35:16


    On this episode of Vitality Radio, Jared breaks down the emerging “GLP-1 economy” and what it means for your health, your food choices, and the future of nutrition. As medications like Ozempic and Wegovy reshape appetite and metabolism, the food industry is rapidly adapting—often with marketing that doesn't match the reality of what's inside the package. Jared explores the growing protein trend, why it matters, and where it can mislead consumers when ultra-processed foods are simply rebranded as “high-protein” or “GLP-1 friendly.” He shares practical insights to help you make informed decisions, emphasizing whole-food protein sources, label literacy, and metabolic awareness. This episode is your guide to navigating modern nutrition trends with clarity and confidence—without falling for the hype.Products:GLP-1 Metabolic OptimizerAdditional Information:The Ozempic Economy - How Ozempic Changed Food Forever#627: GLP-1 Explained Part 1: How to Support Metabolism Without Drugs#628: GLP-1 Explained Part 2: The Lifestyle Blueprint for Real Metabolic OptimizationVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

    Pod Save America
    J. Edgar Boozer

    Pod Save America

    Play Episode Listen Later Apr 21, 2026 95:01


    FBI Director Kash Patel sues The Atlantic for defamation after they publish a well-sourced article alleging he's frequently drunk on the job. Donald Trump celebrates the reopening of the Strait of Hormuz — only to watch Iran close the strait and fire on two ships. The administration tries to win back Joe Rogan and his audience by fast-tracking a series of psychedelics for FDA approval. Potential 2028 contenders, including Jon Ossoff, Pete Buttigieg, and Kamala Harris, make high-profile appearances on the campaigns trail. Plus: J Street's Ilan Goldenberg talks to Tommy about what progressive, pro-Israel policy should look like.For a closed-captioned version of this episode, click here. For a transcript of this episode, please email transcripts@crooked.com and include the name of the podcast.

    The Todd Herman Show
    Joe Rogan Gets Legal Mushrooms, YOU Get an Even WORSE CDC Ep-2670

    The Todd Herman Show

    Play Episode Listen Later Apr 21, 2026 44:30 Transcription Available


    Alan's Soap https://AlansSoaps.com/ToddHonor John's memory and the legacy he created for Ian and Alan with Alan's Artisan Soaps “John's Favorites” bundle.  Get one bar of each of his favorites for only $28.99. Bulwark Capital https://KnowYourRiskPodcast.comBe confident in your portfolio with Bulwark! Schedule your free Know Your Risk Portfolio review. Go to KnowYourRiskPodcast.com today. Renue Healthcare https://Renue.Healthcare/ToddYour journey to a better life starts at Renue Healthcare. Visit https://Renue.Healthcare/Todd Bonefrog https://BonefrogCoffee.com/ToddGet the new limited release, The Sisterhood, created to honor the extraordinary women behind the heroes. Use code TODD at checkout to receive 10% off your first purchase and 15% on subscriptions.LISTEN and SUBSCRIBE at:The Todd Herman Show - Podcast - Apple PodcastsThe Todd Herman Show | Podcast on SpotifyWATCH and SUBSCRIBE at: Todd Herman - The Todd Herman Show - YouTubeOn one hand, this is really cool. On the other hand, it's horrible how it happened. Here's why I believe this is a distraction from the appointment of an even WORSE CDC director.Episode links:WOW! Joe Rogan reveals President Trump IMMEDIATELY offered him FDA approval for a psychedelic treatment in a text chain Because the data was SO CONVINCING and STUNNING "I wanna tell everybody how this happened. I send President Trump some information." The Executive Order: Accelerating Medical Treatments For Serious Mental Illness RFK Jr. NUKED THE ROOM: “Why were mental health professionals pushing sex change operations on 14-year-old kids?” RFK: “It was a multi billion dollar industry…the corruption follows the money.” THIS IS UNRESTRICTED WARFARE AGAINST CHILDREN HEALTH SEC. RFK JR. JUST EXPOSED IT. 2 little girls without vaccinations for measles DIED in the hospital because the hospital refused to give them proper care. RFK Jr just destroyed Democratic attempts to say Tylenol is NOT linked to Autism Foxx: A new Danish study shows Tylenol is not linked to autism GREGORIO CASAR: “When somebody's health insurance cost goes up $500 a month because of Donald Trump's policy…” RFK JR: “The health insurance companies' stocks rose by 1000% after Obamacare was passed.” “The money was not going to Americans. It was going to THEM, and it was YOU who did it.” This is Amy Eskridge. She is one of the 11 scientists who has died/disappeared recently that's linked to high government research and secrets. Amy researched anti-gravity and in this clip reveals anti-gravity was already discovered 4 times, but each time the government suppressed it. She then reveals she was close to discovering it, but was threatened that she would be killed if she published it. Ken Captain: “I am currently undergoing Life saving Treatment from horrific damage from the Pfizer COVID 19 vaccines. I am here in Japan at Edogawa Hospital. “

    The David Knight Show
    Tue Episode #2248: Trump Pushed Psychedelics at Warp Speed — Stocks Jumped 28% Overnight

    The David Knight Show

    Play Episode Listen Later Apr 21, 2026 122:00


    ──────────────────────────────────────── [00:02:08] Grassroots Opposition Killed the Federal Cell Tower Bill — Local Governments Keep Authority A GOP bill that would have stripped local governments of authority to reject cell tower placement near homes, schools, and parks was shelved after opposition led by Children's Health Defense. ──────────────────────────────────────── [00:12:12] Trump Pushed Psychedelics at Warp Speed — One-to-Two Month FDA Review Target Trump directed the FDA to give psychedelics national priority vouchers with a one-to-two month timeline — psychedelics stocks jumped 13-28% immediately. ──────────────────────────────────────── [00:52:16] Q-Style Telegram Posts Reframing the Iran War as a Trump Victory — Knight: Same Script as Always A listener forwarded Telegram posts framing the Hormuz blockade and Epstein files as synchronized Trump victories — Knight: you can manufacture a post-hoc defense for anything if you lie about it. ──────────────────────────────────────── [01:01:14] Knight Plays WWE Blading Tutorial to Explain Trump's Butler Ear — MTG Now Questioning It Knight plays a wrestling exposé showing how wrestlers fake bloody wounds with hidden razor blades — Trump's ear bled, then healed with no cartilage notch, and the FBI stonewalled the House investigation. ──────────────────────────────────────── [01:13:19] Trump Teasing UFO Document Release — Knight: Next Distraction From Epstein, Same Pattern Trump says UFO files are coming "very soon" — Knight: standard playbook of distraction, diversion, and disinformation, bipartisan deception just like 9/11 and COVID. ──────────────────────────────────────── [01:20:41] RT: Trump Lied Seven Times in One Hour Saturday — Posted Through 4 AM Including the Jesus Meme RT documented Trump's Saturday lies alongside Sisson's overnight timeline showing the Jesus meme at 9:49 PM and activity at 4:10 AM — Knight: he is not sleeping, he is not well. ──────────────────────────────────────── [01:24:05] Trump Announced He Prohibited Israeli Strikes on Lebanon — Knight: WWE Theater to Reclaim Boss Image Trump wrote that the US has prohibited further Israeli strikes on Lebanon, leaving Netanyahu "personally stunned" — Knight: WWE theater to reclaim the boss image after people called him Netanyahu's puppet. ──────────────────────────────────────── [01:30:00] Iran Suspended Petrochemical Exports — Israeli Strikes Cut Iranian Oil Production by 50% Israeli strikes damaged Iran's petrochemical hubs and power lines, forcing Iran to suspend petrochemical exports — Knight: so what exactly is the US blockade blocking? ──────────────────────────────────────── [01:43:13] IDF Soldier Smashed a Jesus Statue in a Christian Village in Lebanon — IDF Confirmed the Photo Is Authentic An IDF soldier photographed smashing a Jesus statue with a sledgehammer in Debel, a Christian village in southern Lebanon — France 24 verified it, the IDF confirmed it, and Trump has been completely silent. ──────────────────────────────────────── [01:53:28] Pew Study: Jews Have a Net Negative 40% View of Evangelical Christians — Their Biggest Supporters A Pew graphic shows Jews have a net negative 40% opinion of evangelical Christians — the very group that polls at 39% favorable toward Jews and defends Israel most loudly. ──────────────────────────────────────── Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silver For 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code “KNIGHT” For high quality made in America products go to HomeSteadProducts.shop and use promo code “Knight” for 10% off your purchases Find out more about the show and where you can watch it at TheDavidKnightShow.com If you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-david-knight-show--2653468/support.

    The Patrick Madrid Show
    The Patrick Madrid Show: April 21, 2026 - Hour 3

    The Patrick Madrid Show

    Play Episode Listen Later Apr 21, 2026 49:06


    Patrick carries listeners through heated news about abortion drugs, and a lively back-and-forth on Catholic teachings around Communion. Prayer, perseverance, and even moose encounters in Alaska surface. Unpredictable, genuine exchanges pop up, from a young caller's First Communion anticipation to reminders—keep going. Audio: Keep going - https://x.com/art0flife_/status/2032854223411437998?s=46&t=m_l2itwnFvka2DG8_72nHQ (0:20) Trump Justice Dept asks to dismiss FLORIDA's case against the FDA for allowing mail-order abortion drugs (06:50) Rebecca - My in-laws Our Lutheran. How can I explain to them why they can't receive Communion at a Catholic church? (10:33) David - Is it a sin if I didn't go to Mass because there was no priest here? (21:01) Tim - Some people don't believe that you have to talk to a priest. Why do you need a priest as a mediator? (28:10) Big Brother is Watching: Federal Surveillance Tech Becomes Mandatory in New Cars by 2027 (37:50) Noah (7-years-old) - If a priest could go to Confession, how would he do it? (47:35) Originally Aired on 03-16-2026

    The REAL David Knight Show
    Tue Episode #2248: Trump Pushed Psychedelics at Warp Speed — Stocks Jumped 28% Overnight

    The REAL David Knight Show

    Play Episode Listen Later Apr 21, 2026 122:00


    ──────────────────────────────────────── [00:02:08] Grassroots Opposition Killed the Federal Cell Tower Bill — Local Governments Keep Authority A GOP bill that would have stripped local governments of authority to reject cell tower placement near homes, schools, and parks was shelved after opposition led by Children's Health Defense. ──────────────────────────────────────── [00:12:12] Trump Pushed Psychedelics at Warp Speed — One-to-Two Month FDA Review Target Trump directed the FDA to give psychedelics national priority vouchers with a one-to-two month timeline — psychedelics stocks jumped 13-28% immediately. ──────────────────────────────────────── [00:52:16] Q-Style Telegram Posts Reframing the Iran War as a Trump Victory — Knight: Same Script as Always A listener forwarded Telegram posts framing the Hormuz blockade and Epstein files as synchronized Trump victories — Knight: you can manufacture a post-hoc defense for anything if you lie about it. ──────────────────────────────────────── [01:01:14] Knight Plays WWE Blading Tutorial to Explain Trump's Butler Ear — MTG Now Questioning It Knight plays a wrestling exposé showing how wrestlers fake bloody wounds with hidden razor blades — Trump's ear bled, then healed with no cartilage notch, and the FBI stonewalled the House investigation. ──────────────────────────────────────── [01:13:19] Trump Teasing UFO Document Release — Knight: Next Distraction From Epstein, Same Pattern Trump says UFO files are coming "very soon" — Knight: standard playbook of distraction, diversion, and disinformation, bipartisan deception just like 9/11 and COVID. ──────────────────────────────────────── [01:20:41] RT: Trump Lied Seven Times in One Hour Saturday — Posted Through 4 AM Including the Jesus Meme RT documented Trump's Saturday lies alongside Sisson's overnight timeline showing the Jesus meme at 9:49 PM and activity at 4:10 AM — Knight: he is not sleeping, he is not well. ──────────────────────────────────────── [01:24:05] Trump Announced He Prohibited Israeli Strikes on Lebanon — Knight: WWE Theater to Reclaim Boss Image Trump wrote that the US has prohibited further Israeli strikes on Lebanon, leaving Netanyahu "personally stunned" — Knight: WWE theater to reclaim the boss image after people called him Netanyahu's puppet. ──────────────────────────────────────── [01:30:00] Iran Suspended Petrochemical Exports — Israeli Strikes Cut Iranian Oil Production by 50% Israeli strikes damaged Iran's petrochemical hubs and power lines, forcing Iran to suspend petrochemical exports — Knight: so what exactly is the US blockade blocking? ──────────────────────────────────────── [01:43:13] IDF Soldier Smashed a Jesus Statue in a Christian Village in Lebanon — IDF Confirmed the Photo Is Authentic An IDF soldier photographed smashing a Jesus statue with a sledgehammer in Debel, a Christian village in southern Lebanon — France 24 verified it, the IDF confirmed it, and Trump has been completely silent. ──────────────────────────────────────── [01:53:28] Pew Study: Jews Have a Net Negative 40% View of Evangelical Christians — Their Biggest Supporters A Pew graphic shows Jews have a net negative 40% opinion of evangelical Christians — the very group that polls at 39% favorable toward Jews and defends Israel most loudly. ──────────────────────────────────────── Money should have intrinsic value AND transactional privacy: Go to https://davidknight.gold/ for great deals on physical gold/silver For 10% off Gerald Celente's prescient Trends Journal, go to https://trendsjournal.com/ and enter the code “KNIGHT” For high quality made in America products go to HomeSteadProducts.shop and use promo code “Knight” for 10% off your purchases Find out more about the show and where you can watch it at TheDavidKnightShow.com If you would like to support the show and our family please consider subscribing monthly here: SubscribeStar https://www.subscribestar.com/the-david-knight-showOr you can send a donation throughMail: David Knight POB 994 Kodak, TN 37764Zelle: @DavidKnightShow@protonmail.comCash App at: $davidknightshowBTC to: bc1qkuec29hkuye4xse9unh7nptvu3y9qmv24vanh7Become a supporter of this podcast: https://www.spreaker.com/podcast/the-real-david-knight-show--5282736/support.

    The Bid Picture - Cybersecurity & Intelligence Analysis
    487. The Brief - April 21, 2026

    The Bid Picture - Cybersecurity & Intelligence Analysis

    Play Episode Listen Later Apr 21, 2026 16:04 Transcription Available


    Check out host Bidemi Ologunde's new show: The Work Ethic Podcast, available on Spotify and Apple Podcasts.Email: bidemiologunde@gmail.comIn this episode, host Bidemi Ologunde examines the key global signals from April 13 to April 19, 2026: resignations and instability in the U.S. Congress, the political scramble over the looming FISA 702 expiration, and the growing sense that AI is becoming harder to control. What does it mean when political institutions look weaker just as surveillance systems and frontier AI models become more powerful? Why are governments and regulators sounding the alarm about AI-driven cyber risks while also racing to adopt the same tools? And are this week's headlines, from Washington to the battlefield to public robot spectacles, pointing to a more fragile and more frightening world order?Sponsors and partners:Promeed: 100% mulberry silk pillowcases and bedding that feel incredibly soft, stay breathable, and are naturally gentle on hair and skin.SurviveX: professional-grade FSA/HSA eligible first aid and preparedness kits designed in Virginia, USA and produced in an FDA-registered facility.Alison US CA: Alison is the world's largest free online learning and skills-training platform, helping more than 50 million learners in 193+ countries build career-ready skills with 6,000+ free courses, certificates, and diplomas.eSign (iOS only): eSign is a clean, privacy-first document-signing app that works entirely on your device, letting you sign PDFs, DOCX files, images, and scans, edit and assemble pages, and export crisp 300 DPI PDFs in seconds, without accounts, cloud uploads, or compromising sensitive documents.Support the show

    Diabetes Connections with Stacey Simms Type 1 Diabetes
    In the News.. Stem Cell Research Update, New Patch Pump Approved, GLP-1 Resistance Studied, Big Win T1D School Kids and more!

    Diabetes Connections with Stacey Simms Type 1 Diabetes

    Play Episode Listen Later Apr 21, 2026 10:48


    It's In the News! Every other week we bring you the top diabetes stories and headlines happening now. This week's top stories: stem cell reserach updates, the Pivot patch pump gets FDA approval, GLP-1 Resistance research moves forward, T1D kids in VA get a big win, time of day for exercise matters, and much more! Don't miss our 2026 events - Club 1921 and Moms' Night Out info here Announcing Community Commericals! Learn how to get your message on the show here. Learn more about studies and research at Thrivable here Please visit our Sponsors & Partners - they help make the show possible! Omnipod - Simplify Life All about Dexcom  All about VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com 

    The Diary Of A CEO by Steven Bartlett
    The Peptide Expert: Big Pharma Are Hiding This Powerful Peptide From You! - Dr. Alex Tatem

    The Diary Of A CEO by Steven Bartlett

    Play Episode Listen Later Apr 20, 2026 89:35


    The FDA silently banned 19 peptides overnight, now RFK Jr is reversing it all. Dr Alex Tatem reveals the truth behind the cover-up, and what peptides can really do for your body. Dr. Alex Tatem is an internationally recognised urologist who has studied peptides for 12 years and runs a men's health clinic. He also hosts a YouTube channel dedicated to demystifying peptides and men's health. In this  explains: ◼ What peptides are, how they work, and which ones target your health problem ◼Why the peptide industry is quietly approaching the size of the entire AI sector ◼ Why male fertility is collapsing globally and what's silently driving it ◼ What low testosterone is doing to your body and how to fix it ◼ Why 30 million men with erectile dysfunction are never told about the most effective fix 00:00 Intro 00:03:15 What Exactly Is A Peptide—and Why It Matters More Than You Think 00:05:14 The “Lock” Explained: How Peptides Actually Work In Your Body 00:08:34 Why Peptides Are Suddenly Everywhere (And What Changed) 00:11:09 The Real Role Of Compounding Pharmacies—And Why They're Controversial 00:17:16 Are Pharma Companies Prioritizing Profits Over Patients? 00:20:22 Why Peptides Are Back After Being Banned—What Happened Behind The Scenes 00:20:56 The Most Shocking Patient Transformation From Peptides 00:22:26 When You Should (And Shouldn't) Use Peptides In Your Life 00:24:28 The Latest FDA Update: What It Means For Peptide Access 00:26:05 How People Are Actually Getting “Illegal” Peptides 00:27:41 How To Take Peptides Safely—What Most People Get Wrong 00:29:38 Why Big Pharma Feels Threatened By Peptides 00:33:53 The Exact Peptides Alex Uses—And His Reasons Why 00:37:49 How Peptides Could Transform Your Insulin Levels 00:38:42 Do Peptides Work As Creams? What You Need To Know 00:40:30 How Peptides May Unlock Better Cognitive Performance 00:42:58 The Future Of Muscle Retention On GLP-1s—What's Coming Next 00:48:03 Ads 00:49:05 The Hidden Trade-Offs Of Peptides No One Talks About 00:52:09 The Real Benefits Of Different Peptides—And How They Compare 00:57:30 The Peptide That Could Change Your Sleep Quality 01:01:58 What Happens When You Stop Taking GLP-1s? 01:05:40 Ads 01:07:33 Is There A “Super Peptide” For Anti-Aging? 01:11:04 The Truth About Peptides And Erectile Dysfunction 01:11:56 Why Medicine Burned Me Out—And What It Reveals About The System 01:18:57 The Enhanced Games Explained—And Why They're So Controversial 01:22:46 How To Improve Erections—What Actually Works Enjoyed the episode? Share this link and earn points for every referral - redeem them for exclusive prizes: https://doac-perks.com  Independent Research Document: https://stevenbartlett.com/wp-content/uploads/2026/04/DOAC-Alex-Tatum-Independent-Research-Further-Reading.pdf Follow Dr Alex:  X - https://link.thediaryofaceo.com/DS0mGd3  Instagram - https://link.thediaryofaceo.com/36mqqnE  YouTube - https://link.thediaryofaceo.com/4SagDuv  Website - https://link.thediaryofaceo.com/5WRUIrQ  The Diary Of A CEO: ◼️Join DOAC circle here - https://doaccircle.com/  ◼️Buy The Diary Of A CEO book here - https://smarturl.it/DOACbook  ◼️The 1% Diary is back - limited time only: https://bit.ly/3YFbJbt  ◼️The Diary Of A CEO Conversation Cards (Second Edition): https://g2ul0.app.link/f31dsUttKKb  ◼️Get email updates - https://bit.ly/diary-of-a-ceo-yt  ◼️Follow Steven - https://g2ul0.app.link/gnGqL4IsKKb Sponsors: Pipedrive - https://pipedrive.com/CEO   LinkedIn Marketing - https://www.linkedin.com/DIARY Wispr - Get 14 days of Wispr Flow for free at https://wisprflow.ai/steven

    Techmeme Ride Home
    Robots Winning The (Literal) Race

    Techmeme Ride Home

    Play Episode Listen Later Apr 20, 2026 21:42


    Vercel confirmed a breach traced to an AI platform's compromised OAuth app. The NSA is using Anthropic's Mythos despite the Pentagon blacklist. Mac Minis face 12-week wait times from AI agent demand, and humanoid robots crushed the Beijing half-marathon. Vercel says its internal systems were accessed after a Vercel employee's Google Workspace account was compromised via a breach at the AI platform Context.ai (BleepingComputer) Sources: the US NSA is using Mythos Preview; one source says Mythos is also being widely used within the DoD, despite Anthropic's supply chain risk designation (Axios) Adobe introduces CX Enterprise, an AI agent-based platform that aims to help corporate customers automate digital marketing and other functions (WSJ) Some Mac Mini and Mac Studio models are unavailable or facing up to 12-week wait times in the US, with analysts citing strong demand from AI agent power users (WSJ) Deezer says AI-generated tracks now account for 44% of daily uploads, totaling ~75K tracks per day and 2M+ per month, but account for just 1-3% of consumption (TechCrunch) Sources: Recursive Superintelligence, a four-month-old start-up developing self-teaching AI and founded by ex-DeepMind and OpenAI engineers, has raised $500M+ (FT) At the Beijing half-marathon, several humanoid robots beat human winners by 10+ minutes; a robot made by Honor beat the human world record held by Jacob Kiplimo (Reuters) Disclaimer: ● Initial 3 week subscription and 4 weeks of medication from $79 plus tax and $179 per month plus tax for 12 week subscription thereafter. Final pricing depends on program selection. ● Noom GLP-1Rx Program involves healthy diet, exercise and support. Individual results vary. Meds & personalization based on clinical need. Not reviewed by FDA for safety, efficacy, or quality. No affiliation with Novo Nordisk Inc., the only US source of FDA-approved semaglutide. Not available in all 50 US states ● Based on an analysis of self reported data from 1,254 engaged Noom users. Learn more about your ad choices. Visit megaphone.fm/adchoices

    NonMembers Only
    #237 - The Enhanced Games CEO Interview, Flip Flop Hiking, & Kelce Fatigue?

    NonMembers Only

    Play Episode Listen Later Apr 20, 2026 82:40


    Happy National Boston Marathon Day! We kick off the episode with some very realistic running motivation, reminding everyone that making it to the start line with your bodily fluids sorted out is half the battle, and taking a trip to the medical tent just means you get a cooler story. We recount Erin's brutal weekend "marathon" hike up Pulpit Rock, which featured Dan hiking in flip flops and eventually having to shove a 40 pound, heavily breathing Bucky the pug into his backpack. Erin also gives a week two update on her "Pull-Up Revolution," celebrating the awakening of her "sleeper cell muscles". Erin then spirals over her invite to the Dick's Sporting Goods Varsity Team brand trip in Tampa, specifically stressing over how to dress "camera ready" without looking like she consulted ChatPPP for fashion advice.In niche internet and pop culture news, we cover the genius behind the "Two Cute Labs" (Stink and Bink) who went viral for selling "your ad here" space on their backs. We also discuss the growing "Jason Kelce fatigue" after his appearance at The Masters frustrated traditionalists, and debate the so called decorum decline involving college bros flipping off cameras outside Augusta National.In sports, we break down two disqualifications: Matt Choi getting DQ'd from an Ironman for drafting (and missing the penalty tent because he skipped orientation), and the shocking overturning of a Pokémon Go Regional Championship simply because the winner put his headphones down too forcefully.We then present our very serious, hard hitting journalism segment: an interview with Max Martin, the CEO of the Enhanced Games! We debrief our chat with him, discussing the $1 million world record prizes, the fascinating concept of building a digital first stadium in just four weeks, and how athletes are utilizing FDA approved testing and doctors to compete safely. Finally, we wrap up with a heartwarming "No Bad, No Sad" story about King Randall's program, where he takes young men to the grocery store to teach them essential life skills like picking produce, doing laundry, and speaking with eye contact.

    HAYVN Hubcast
    Reinventing Breast Health with Purpose and Persistence EP 138

    HAYVN Hubcast

    Play Episode Listen Later Apr 20, 2026 26:04


    In this episode of HAYVN Hubcast, host Nancy Sheed speaks with Clémence Bruguier, co-founder of Mirabelle Medical, a company focused on improving breast health access and awareness for women globally. Fresh off winning the most recent HAYVN Hatch competition, Clémence shares her unconventional path into healthcare, despite having no formal medical background, and how her lifelong drive to build purpose-driven projects led her to entrepreneurship. Clémence explains how Mirabelle Medical is addressing a critical gap in women's health: the lack of accessible, easy-to-use tools for regular breast checks. The company is developing two devices, one designed for personal use to help women monitor their breast health between mammograms, and another for healthcare professionals working in underserved regions where access to screening is limited. A key theme throughout the conversation is the power of questioning assumptions. Clémence challenges traditional guidance around breast self-exams and highlights that many women still detect abnormalities on their own. She also points to the surprising reality that a significant percentage of women in the United States do not have access to mammograms, underscoring the urgency for alternative solutions. The episode also offers a candid look at the realities of building a healthcare startup. Clémence shares how Mirabelle began with simple prototypes built in a kitchen, followed by field testing in Ghana that validated both the need and usability of the product. She walks through the pivots required along the way, including shifting from a wellness product to a regulated medical device, navigating FDA approval, and making the difficult decision to refund early customers in order to prioritize doing things the right way. Throughout the conversation, Clémence emphasizes user-centered design, global accessibility, and education. Her work reflects a broader mission to empower women with the tools and knowledge they need to take control of their health, regardless of where they live. Key Points Clémence's entrepreneurial journey is driven by a strong sense of purpose and a desire to build meaningful solutions Mirabelle Medical is focused on making breast health checks more accessible through simple, low-cost devices The company is developing two products for both personal and clinical use Early field testing in Ghana confirmed real demand and practical application A significant number of women in the U.S. still lack access to regular mammograms The company pivoted from a wellness product to a regulated medical device requiring FDA approval Education and cultural awareness are essential components of improving global breast health Building in healthcare requires resilience, adaptability, and a willingness to navigate complex systems This episode highlights what it really takes to build something meaningful in a complex and highly regulated space. Clémence's journey is a clear example of how purpose, persistence, and a willingness to learn can drive innovation that matters. As women's health continues to gain long-overdue attention, solutions like Mirabelle Medical are helping to close critical gaps and empower women everywhere to take a more active role in their care. Connect with Nancy LinkedIn  Instagram Website Connect with Clémence Clémence Bruguier - Making Breast Health Accessible | LinkedIn Website Mirabelle Medical | LinkedIn Substack Learn more about your ad choices. Visit megaphone.fm/adchoices

    The Newsmax Daily
    Shadow Briefings: Power, Secrets, and the New Cold Front

    The Newsmax Daily

    Play Episode Listen Later Apr 20, 2026 26:38


    -Former CIA analyst Fred Fleitz joins “America Right Now” to discuss the evolving crisis in Iran. -“Iran has proven once again you can't trust their word.” - Rep. James Comer, House Oversight Committee. -Border Czar Tom Homan says it's ‘just ridiculous' to defund DHS at a time of heightened risk. -A rare Saturday morning press conference in the oval office as President Trump signs an executive order to fast track FDA review of psychedelic drugs. -Ten elite scientists linked to UFO research have vanished or died under mysterious circumstances, and the world is demanding answers. “The Right Squad” breaks down the chilling details. Today's podcast is sponsored by : NOBLE GOLD - Don't wait six months from now wishing you had positioned earlier. Have the conversation now. Schedule a free gold strategy session at http://NobleGoldInvestments.com/NEWSMAX Listen to Newsmax LIVE and see our entire podcast lineup at ⁠http://Newsmax.com/Listen⁠ Make the switch to NEWSMAX today! Get your 15 day free trial of NEWSMAX+ at ⁠http://NewsmaxPlus.com⁠ Looking for NEWSMAX caps, tees, mugs & more? Check out the Newsmax merchandise shop at : ⁠http://nws.mx/shop⁠ Follow NEWSMAX on Social Media:  -Facebook: ⁠http://nws.mx/FB⁠  -X/Twitter: ⁠http://nws.mx/twitter⁠ -Instagram: ⁠http://nws.mx/IG⁠ -YouTube: ⁠https://youtube.com/NewsmaxTV⁠ -Rumble: ⁠https://rumble.com/c/NewsmaxTV⁠ -TRUTH Social: ⁠https://truthsocial.com/@NEWSMAX⁠ -GETTR: ⁠https://gettr.com/user/newsmax⁠ -Threads: ⁠http://threads.net/@NEWSMAX⁠  -Telegram: ⁠http://t.me/newsmax⁠  -BlueSky: ⁠https://bsky.app/profile/newsmax.com⁠ -Parler: ⁠http://app.parler.com/newsmax⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

    Badlands Media
    Badlands Daily: 4/20/26 - Ibogaine EO, Kash Drops Bombs, Swalwell Purge Expands

    Badlands Media

    Play Episode Listen Later Apr 20, 2026 111:46


    CannCon and Zak Paine kick off the week with a Monday full of genuinely big news, starting with Trump's executive order to fast-track FDA approval of Ibogaine for addiction, PTSD, and mental illness. Zak shares his personal perspective as a recovering addict, and the guys tear apart the pharmaceutical industrial complex's stranglehold on mental health treatment. Kash Patel goes on Maria Bartiromo and all but confirms the FBI has the goods on 2020 election fraud, with arrests on the horizon. Harmeet Dillon follows up on DOJ housecleaning and voter roll integrity. Joe DeGenova is tapped to lead the John Brennan criminal investigation. The Swalwell files keep expanding as Anna Paulina Luna tells Catherine Herridge a Capitol Hill purge is coming. Plus, a GAO report drops on Tax Day revealing up to $521 billion in annual federal fraud, birthright citizenship numbers, deportees headed to the Congo, and the Macon County election officials caught in a healthcare fraud scheme.

    Fat Science
    New Obesity Drugs: What's FDA Approved and What's Coming

    Fat Science

    Play Episode Listen Later Apr 20, 2026 47:38


    The obesity medication landscape just changed — again. One brand-new pill is already in pharmacies, and five more are in various stages of approval. But the real story isn't the drugs themselves: it's what they're revealing about how your metabolism actually works, and why willpower was never the problem.This week on Fat Science, Dr. Emily Cooper, Mark Wright, and Andrea Taylor break down six metabolic medications — two newly FDA-approved and four in the pipeline — covering everything from a flexible new oral GLP-1 pill to drugs that target the brain's central metabolic pathway directly. Dr. Cooper explains the science behind each one, who might benefit, and what the pipeline tells us about the future of metabolic care. This is the most comprehensive drug update the show has done, and it arrives at a moment when the field is moving faster than ever.Key TakeawaysFoundayo (orforglipron), approved April 1st, is the first small molecule oral GLP-1 — no empty stomach requirement, no cold chain, and potentially lower production costs long-term.The amylin hormone may uniquely address both "I'm nourished" and "I weigh enough" signals in the brain — making the amylin pathway a powerful and underutilized target.Retatrutide (Lilly's triple agonist targeting GLP-1, GIP, and glucagon receptors) is showing unprecedented effectiveness plus significant non-scale benefits, including fatty liver reduction — but is still years from approval.The brain's melanocortin 4 receptor is the CEO of metabolism — regulating energy expenditure, appetite, and insulin — and new drugs targeting it represent the deepest intervention yet.Many of these medications are showing weight-independent benefits, including improvements in kidney, liver, cardiovascular risk, sleep apnea, and joint health that have nothing to do with how much weight is lost.Notable Quote"Everybody focuses on appetite, and you just need to eat less. But now with these medications and how they actually affect our biology, it becomes very clear that there's so much more to this." — Dr. Emily CooperLinks & ResourcesPodcast Home: fatsciencepodcast.comCooper Center for Metabolism: coopermetabolic.comResources from Dr. Cooper: coopermetabolic.com/resourcesJoin Our Community: patreon.com/cw/FatSciencePodcastSubmit Your Question: questions@fatsciencepodcast.com or dr.c@fatsciencepodcast.comFat Science is supported by the Diabesity Institute, a nonprofit dedicated to increasing access to effective, science-based metabolic care.Disclaimer: This podcast is for informational purposes only and is not intended as medical advice. Please consult with a qualified healthcare provider for personalized recommendations.

    Pharma and BioTech Daily
    Kailera IPO Raises $625M for Obesity Drug | Pharma and Biotech Daily

    Pharma and BioTech Daily

    Play Episode Listen Later Apr 20, 2026 5:19


    Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we explore China's burgeoning role in the synthetic biology sector, as outlined in a recent article discussing China's strategic focus on biotechnology within its latest five-year plan. This strategy identifies biomanufacturing, particularly synthetic biology and genetic engineering, as pivotal for China's emerging bioeconomy. The nation's approach frames biology as a transformative industrial platform poised to reshape pharmaceuticals, materials science, agriculture, and energy industries. Central to this transformation is DNA synthesis, which allows for the design and manufacture of genetic sequences. As China rapidly expands its synthetic biology capabilities, questions arise about its potential to become an innovation powerhouse, the competitiveness of Chinese firms in DNA synthesis, and geopolitical factors affecting international cooperation and supply chains. Insights from industry leaders highlight China's unique industrialization strengths. The country excels in rapidly scaling technologies due to its ability to mobilize capital, infrastructure, and manufacturing swiftly—a capability that surpasses Europe and the U.S. This aligns with China's national biomanufacturing strategy aimed at developing vast production systems across pharmaceuticals and industrial biotechnology. Beyond sheer manufacturing capacity, China is constructing a comprehensive ecosystem to bolster advanced biotechnology. The nation's development of clinical infrastructure and pharmaceutical manufacturing is noteworthy. China is actively exploring personalized therapies and building regulatory pathways for advanced treatments, signaling a potential shift in global biotech dynamics. Domestically, Chinese companies are developing technology platforms to reduce dependence on imported equipment and Western supply chains. The competitive landscape in DNA synthesis is evolving beyond traditional commodity-versus-innovation narratives, as both Chinese and Western companies pursue similar technological advancements. However, geopolitical tensions complicate collaborations between Chinese and Western firms. Export controls highlight the growing barriers to cooperation. Despite price competitiveness from Chinese DNA synthesis providers, concerns over data security and regulatory risks are prompting some Western buyers to favor suppliers from Europe or the US. Shifting gears to regulatory matters, recent developments highlight a dynamic industry characterized by scientific advancements, regulatory shifts, legal battles, and strategic corporate maneuvers. Central to these is the call for enhanced transparency and evidence standards in the FDA's accelerated approval pathway. Strengthening evidence requirements aims to ensure that drugs approved under this pathway are supported by robust scientific data, ultimately safeguarding patient health and maintaining public trust in regulatory institutions. A landmark financial event has unfolded with Kailera Therapeutics' record-breaking IPO, raising $625 million to bolster its obesity treatment pipeline. This significant capital inflow not only sets a new benchmark for biotech IPOs but also underscores burgeoning interest in addressing obesity—an area with substantial unmet medical needs. In legal arenas, Teva Pharmaceuticals scored a victory as an appeals court revived a $177 million verdict against Eli Lilly concerning patent disputes over migraine medications. Additionally, Viatris and Teva have initiated recalls due to issues with drug dissolution and raw material approvals. The appointment of Dr. Erica Schwartz as the potential Director of the CDC marks another pivotal moment. Her leadership could steer the CDC towards more effective public health responses. On a broader industry scale, there is anSupport the show

    The Bid Picture - Cybersecurity & Intelligence Analysis
    486. The April 30 Question: Renew FISA Section 702 or Not?

    The Bid Picture - Cybersecurity & Intelligence Analysis

    Play Episode Listen Later Apr 19, 2026 17:14 Transcription Available


    Check out host Bidemi Ologunde's new show: The Work Ethic Podcast, available on Spotify and Apple Podcasts.Email: bidemiologunde@gmail.comIn this episode, host Bidemi Ologunde examines the upcoming expiration of Section 702 of the Foreign Intelligence Surveillance Act (FISA) and asks what it really means for everyday Americans. How did a surveillance authority designed to target foreigners overseas become a flashpoint in the debate over Americans' privacy rights? Where did Section 702 come from, and how far back do its origins go in the history of U.S. intelligence reform and post-9/11 surveillance expansion? And as Congress faces another deadline, what protections exist, what loopholes remain, and who could be affected if the law is renewed, changed, or allowed to lapse?Sponsors and partners:Promeed: 100% mulberry silk pillowcases and bedding that feel incredibly soft, stay breathable, and are naturally gentle on hair and skin.SurviveX: professional-grade FSA/HSA eligible first aid and preparedness kits designed in Virginia, USA and produced in an FDA-registered facility.Alison US CA: Alison is the world's largest free online learning and skills-training platform, helping more than 50 million learners in 193+ countries build career-ready skills with 6,000+ free courses, certificates, and diplomas.eSign (iOS only): eSign is a clean, privacy-first document-signing app that works entirely on your device, letting you sign PDFs, DOCX files, images, and scans, edit and assemble pages, and export crisp 300 DPI PDFs in seconds, without accounts, cloud uploads, or compromising sensitive documents.Support the show

    Ranch It Up
    Products To Combat Flies & New World Screwworm & Top Brahman Genetics

    Ranch It Up

    Play Episode Listen Later Apr 19, 2026 27:00


    It's The Ranch It Up Radio Show! Join Jeff Tigger Erhardt, Rebecca Wanner AKA BEC and their crew as they hear how Merck Animal Health has a new product to combat new world screwworm and flies. We find out where and when to get those fancy tiger striped Brahman cross females and brahman genetics.  Plus, the latest news, the ranch channel sales calendar and lots more all wrapped into this brand-new episode of The Ranch It Up Radio Show.  Be sure to subscribe on your favorite podcasting app or on the Ranch It Up Radio Show YouTube Channel. Season 6, EPISODE 285 Merck Exzolt Cattle CA1: Solution To New World Screwworm A first-of-its-kind FDA conditionally approved pour-on for New World screwworm and cattle fever tick. EXZOLT™ CATTLE-CA1 is indicated for the prevention and treatment of infestations caused by New World screwworm (Cochliomyia hominivorax) larvae (myiasis) and treatment and control of cattle fever tick (Rhipicephalus microplus) in beef cattle 2 months of age and older and replacement dairy heifers less than 20 months of age. Not for use in bulls intended for breeding 1 year of age and older, dairy calves, and veal calves. EXZOLT™ CATTLE-CA1 is a ready-to-use topical formulation intended for direct application to the hair and skin in a narrow strip extending along the dorsal midline from the withers to the base of the tail (see Figure 1). The recommended rate of administration is 1 mL/44.1 lbs. (1 mL/20 kg) body weight, which is equivalent to 1.13 mg of fluralaner for each pound (2.5 mg/kg) body weight. Effectiveness has not been evaluated in cattle with wet hides. Find out more about EXZOLT™ CATTLE-CA1 HERE Mississippi Select Brahman & F1 Sale:  An Elite Group Of Brahman & Brahman-Influenced Cattle A consistent, dependable set of cattle that represents the kind of cattle the region is known for! If you're serious about building a more productive, resilient herd in the Southeast, the Mississippi Select Brahman & F1 Sale is shaping up to be one of the most important cattle events of 2026. Designed with real-world cattlemen in mind, this new consignment-based sale brings together top-tier Brahman and Brahman-influenced cattle from proven programs—offering genetics that thrive in heat, humidity, and challenging pasture conditions. What To Expect At The Sale Registered Brahman Cattle Proven genetics from reputable breeders Strong maternal lines and performance traits Ideal seedstock for herd improvement F1 (Brahman Influenced) Cattle Highly sought after for commercial operations Known for hybrid vigor, fertility, and efficiency Excellent for crossbreeding programs. For complete details, click HERE Featured Experts in the Cattle Industry John Hutchinson, Ph.D. - Merck Animal Health https://www.merck-animal-health-usa.com/ Follow On Facebook: @MerckAnimalHealth Seth Maxie - Mississippi Select Brahman & F1 Sale Mississippi Select Brahman & F1 Sale Follow On Facebook: @MississippiSelectSale Shaye Wanner – Host of Casual Cattle Conversation https://www.casualcattleconversations.com/ Follow on Facebook: @cattleconvos Contact Us with Questions or Concerns Have questions or feedback? Feel free to reach out via: Call/Text: 707-RANCH20 or 707-726-2420 Email: RanchItUpShow@gmail.com Follow us: Facebook/Instagram: @RanchItUpShow YouTube: Subscribe to Ranch It Up Channel: https://www.youtube.com/c/RanchItUp Catch all episodes of the Ranch It Up Podcast available on all major podcasting platforms. Discover the Heart of Rural America with Tigger & BEC Ranching, farming, and the Western lifestyle are at the heart of everything we do. Tigger & BEC bring you exclusive insights from the world of working ranches, cattle farming, and sustainable beef production. Learn more about Jeff 'Tigger' Erhardt & Rebecca Wanner (BEC) and their mission to promote the Western way of life at Tigger and BEC. https://tiggerandbec.com/ Industry References, Partners and Resources For additional information on industry trends, products, and services, check out these trusted resources: Allied Genetic Resources: https://alliedgeneticresources.com/ American Gelbvieh Association: https://gelbvieh.org/ Axiota Animal Health: https://axiota.com/multimin-campaign-landing-page/ Imogene Ingredients: https://www.imogeneingredients.com/ Jorgensen Land & Cattle: https://jorgensenfarms.com/#/?ranchchannel=view Medora Boot: https://medoraboot.com/ RFD-TV: https://www.rfdtv.com/ Rural Radio Network: https://www.ruralradio147.com/ Superior Livestock Auctions: https://superiorlivestock.com/ Transova Genetics: https://transova.com/ Westway Feed Products: https://westwayfeed.com/ Wrangler: https://www.wrangler.com/ Wulf Cattle: https://www.wulfcattle.com/

    The Switch Podcast with Andrea from Switch Natural
    Toxic Beauty: The Safety Rules the FDA Just Walked Back

    The Switch Podcast with Andrea from Switch Natural

    Play Episode Listen Later Apr 19, 2026 3:29


    The latest cosmetics legislation (MoCRA) was supposed to transform beauty safety in the U.S. But while we were all distracted during the 2025 holidays, the FDA quietly withdrew key safety rules from it.In this video, I'm breaking down the "MoCRA Betrayal" and the latest regarding Talc, PFAS, and Formaldehyde.IN THIS EPISODE• The Talc Rule Withdrawal: It's not just asbestos.• Teflon in Your Makeup: The FDA found forever chemicals and took zero action.• Formaldehyde Deadlines: Bans on hair-straightening products stall.• The EU vs. The U.S.: FDA at a standstill while Europe moves forward.The bottom line? We can't wait for regulators to keep us safe. We have to do it ourselves.LINKS & RESOURCES• Download the Switch Natural App: https://switchnatural.onelink.me/uZpY/sw1• Read the MoCRA Betrayal Blog: https://www.switchnatural.com/home/themocrabetrayal• Follow on Instagram for a daily dose of non-toxic intel: https://www.instagram.com/switch.natural

    Vitality Radio Podcast with Jared St. Clair
    #631: Clean Oral Care: What Really Belongs in Your Toothpaste? with Bruce Weyman

    Vitality Radio Podcast with Jared St. Clair

    Play Episode Listen Later Apr 18, 2026 42:11


    On this episode of Vitality Radio, Jared interviews Bruce Weyman from David's Toothpaste to break down what truly matters in natural oral care. From hidden ingredients in conventional toothpaste to the rise of cleaner alternatives, they explore how to support oral health with thoughtfully sourced, effective products. You'll learn about hydroxyapatite and its role in supporting enamel health, why ingredient quality and sourcing matter, and how everyday habits like brushing, flossing, and oil pulling can elevate your routine. They also discuss common concerns around ingredients like fluoride and sodium lauryl sulfate, as well as alcohol-based mouthwashes. If you're looking to upgrade your oral care routine for the whole family with cleaner, more intentional products, this episode offers a helpful, educational guide.Products:David's ProductsAdditional Information:#558: What's the Deal with Hydroxyapatite? Sorting Facts from FearVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

    Little Miss Recap
    Reality Roundup April 18th, 2026

    Little Miss Recap

    Play Episode Listen Later Apr 18, 2026 46:26


    Amye and Amanda break down the latest news and gossip from your favorite and least favorite reality tv shows. Approx timestamps:11- 90 Day Fiance and The Single Life22- The Mcbee Dynasty23– Seeking Sister Wife27– Love is Blind28– Secret Lives of Mormon Wives (Can #Momtok survive this?)33– Love After Lockup36– What we are watching Get BONUS content and ad-free episodes! Sign up at:www.littlemissrecap.com/supportOr go directly to Patreon at:www.patreon.com/littlemissrecapListen to my true crime podcast: Murder She Watched at www.murdershewatchedpod.comSUPPORT OUR SPONSORSBlissy helps you wake up with clearer skin, smoother hair, and cooler sleep. Blissy is offering 60-nights risk-free PLUS an additional 30% off when you shop at Blissy.com/LMR. Use code LMR to get an additional 30% off! Your skin and hair will thank you!Hers now offers access to an affordable range of FDA-approved GLP-1 medications, including the Wegovy pill and the Wegovy pen. Visit forhers.com/LMR to get personalized, affordable care that gets you. FACTOR MEALS helps you save time in the kitchen with delicious, nutritious, chef-prepared cuisine. Meals come fully prepared and ready to eat in 2 minutes.Use our link and get 50% off your first box plus free shipping. Visit: www.factormeals.com/littlemiss50off and use code littlemiss50off.MERCH: https://littlemissrecap.threadless.com/I'm on cameo at: https://www.cameo.com/amyearcherGet in touch with us:Facebook: https://www.facebook.com/groups/littlemissrecapFacebook group: https://www.facebook.com/groups/littlemissrecapInstagram: @littlemissrecap Voicemail: www.littlemissrecap.comEmail: amye@littlemissrecap.comYoutube: www.youtube.com/@littlemissrecap Hosted on Acast. See acast.com/privacy for more information.

    The Human Upgrade with Dave Asprey
    Flouride and IQ, Sardinemaxxing, At Home Cancer Cure, Hair Loss Fixes, and more... : 1451

    The Human Upgrade with Dave Asprey

    Play Episode Listen Later Apr 17, 2026 11:04


    This week's stories: ***Virologist Self-Injects Oncolytic Virus Therapy, Achieves 4-Year Remission in Triple-Negative Breast Cancer*** A researcher facing terminal triple-negative breast cancer (28% 5-year survival rate) engineered her own measles and vesicular stomatitis viruses and self-administered seven doses directly into her tumor outside formal clinical infrastructure. Four years cancer-free. Dave breaks down the mechanistic basis for oncolytic virotherapy—why cancer cells can't mount antiviral defenses that healthy tissue can—and the regulatory tension between patient autonomy and FDA gatekeeping on experimental immunotherapies. This is either a triumph of DIY biohacking or a cautionary tale about biosafety; either way, oncolytic virotherapy is accelerating toward mainstream clinical use and forcing a reckoning about access to cutting-edge cancer immunology. Sources: -https://www.dana-farber.org/newsroom/news-releases/2026/virus-based-therapy-boosts-anti-cancer-immune-responses-to-brain-cancer -https://www.eurekalert.org/news-releases/1116087 -https://acgtfoundation.org/news/oncolytic-virus-therapy-for-cancer/ ***Spermidine is the Missing Link Between Fasting and Longevity*** A Nature Cell Biology study across yeast, flies, mice, and humans reveals that fasting triggers longevity exclusively through spermidine—blocking spermidine synthesis ablates every lifespan-extending benefit, cardioprotection, and anti-inflammatory outcome, even with identical caloric restriction. Dave explains why your intermittent fasting protocol is metabolically inert without spermidine, the specific foods highest in bioavailable spermidine (wheat germ, aged cheddar, shiitake mushrooms, fermented foods), and how to time supplementation for maximum autophagy activation. This is the most critical missing variable in fasting-focused biohacking that almost no one is tracking. Sources: -https://www.nature.com/articles/s41556-024-01468-x -https://pubmed.ncbi.nlm.nih.gov/39117797/ -https://oxfordhealthspan.com/blogs/aging-well/spermidine-and-healthy-aging-insights-from-a-2026-nature-review -https://www.glp-1.science/blog/spermidine-autophagy-supplement/ ***Hair Regrowth Breakthrough: SHH-Mimetic Peptides Replace Minoxidil*** Topical peptides mimicking sonic hedgehog signaling (the embryonic pathway that initiates hair follicles) activate dermal papilla stem cells and deliver 65% hair regrowth at 24 weeks versus 40% with minoxidil—with zero systemic absorption and zero cardiovascular risk. Dave covers why minoxidil's vasodilation mechanism is crude (and why it triggers tachycardia and hypertrichosis), how SHH-mimetic peptides directly target the actual biological lever (stem cell activation), and why this mechanistic upgrade should reshape hair loss treatment within 12 months. This is precision medicine applied to cosmetic optimization. Sources: -https://finance.yahoo.com/sectors/healthcare/articles/goodbye-minoxidil-clean-bio-hacking-150800494.html ***"Sardinemaxxing": $1.39 Per Can Delivers 370% B12, 982mg Omega-3s, 96% Selenium*** Canned sardines are experiencing a viral surge on TikTok (#sardinemaxxing: 90,000+ videos) because a single 100-gram serving packs 370% daily B12, 982mg omega-3s, 96% selenium, and 24% vitamin D—all for $1.39. Dave breaks down the nutrient density to cost ratio (superior to wild salmon, fish oil supplements, and selenium stacks), the anti-inflammatory mechanisms (B12 methylation support, selenium-dependent glutathione peroxidase, omega-3 IL-6/TNF-α reduction), and why this represents a biohacker's efficiency play: maximum micronutrition per dollar with zero processing overhead. The shift from complexity back to simplicity. Sources: -https://news.northeastern.edu/2026/04/08/what-is-sardinemaxxing/ ***Fluoride in Community Water Has No Effect on IQ or Cognition — Wisconsin Longitudinal Study*** A seven-decade Wisconsin study tracking 10,317 people from age 16 through 80 finds zero evidence that community water fluoridation (0.7 mg/L, the U.S. recommended level) reduces IQ, impairs cognition, or causes neurotoxicity at any life stage. Dave distinguishes between community-level fluoridation and high-endemic-fluoride regions (2–10 mg/L in parts of Asia), clarifies why the anti-fluoridation narrative became culturally dominant without robust U.S. epidemiological data, and examines why 17+ states reversed fluoridation policy based on flawed evidence transfer. This is a case study in how folklore—even with mechanistic rationale—can override data. Individual choice about fluoride exposure remains valid; cognitive toxicity at community water levels is not supported. Sources: -https://www.sciencenews.org/article/fluoride-drinking-water-iq-no-evidence -https://www.nbcnews.com/health/kids-health/fluoride-water-children-iq-brain-cognition-study-rfk-jr-rcna267328 -https://studyfinds.com/major-study-finds-no-link-between-fluoride-water-lower-iq/ -https://medicalxpress.com/news/2026-04-fluoride-kids-iq-decades-analysis.html -https://jamanetwork.com/journals/jamapediatrics/fullarticle/2828425 -https://ntp.niehs.nih.gov/research/assessments/noncancer/completed/fluoride This episode is designed for biohackers, longevity seekers, and high-performance listeners who want mechanism-level clarity on immunotherapy breakthroughs, fasting optimization, cosmetic stem cell activation, nutrient density efficiency, and evidence-based policy reversals. Host Dave Asprey connects emerging clinical research, decade-long epidemiological data, and real-world optimization protocols into actionable frameworks for extending healthspan, sharpening performance, and distinguishing mechanistic wins from folklore-driven narratives. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: oncolytic virus therapy cancer, measles VSV immunotherapy, DIY biohacking immunotherapy, regulatory gatekeeping cancer treatment, spermidine fasting autophagy, spermidine longevity, intermittent fasting mechanism, wheat germ aged cheddar spermidine, SHH sonic hedgehog hair growth, dermal stem cell activation hair, minoxidil replacement peptide, hair regrowth mechanism, sardinemaxxing TikTok, sardines omega-3 B12 selenium, nutrient density cost ratio, nutrient bioavailability supplements, fluoride IQ study Wisconsin, community water fluoridation safety, fluoride high-exposure risk, anti-fluoridation evidence, biohacking news 2026, longevity research, mechanism-driven biohacking, performance optimization, healthspan extension Thank you to our sponsors! - The One Device | Use code DAVE for $10 off at theonedevice.com/dave - Viome | Check it out at viome.com and use code 10DAVE for 10% off. It's time to stop guessing and start knowing your body. -iRestore | Grow thicker, healthier hair back naturally. Use code DAVE at irestore.com/DAVE Resources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:19 – Virologist Self-Cures Cancer 02:41 – Fasting & Spermidine 04:22 – Hair Loss: Beyond Minoxidil 06:08 – Sardines as a Supplement Stack 07:43 – Fluoride & IQ: The 70-Year Study 09:47 – Final Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    Techmeme Ride Home
    Reed Hastings Rides Into The Sunset

    Techmeme Ride Home

    Play Episode Listen Later Apr 17, 2026 22:15


    Netflix beat on revenue and income but dropped 10%+ on weak Q2 guidance as Reed Hastings exits the board. Anthropic launches Claude Design, OpenAI overhauls Codex Desktop with computer control, and DeepSeek seeks its first outside funding at $10B+. Netflix reports Q1 revenue up 16% YoY to $12.25B, vs. $12.2B est., net income up 83% YoY to $5.28B, and forecasts Q2 EPS and revenue below est.; NFLX drops 10%+ (Bloomberg) Anthropic launches Claude Design, a new experimental product that lets users create visuals like prototypes, slides, one-pagers, and more using Claude (TechCrunch) Sources: Dario Amodei is set to meet with WH Chief of Staff Susie Wiles on Friday, a breakthrough in Anthropic's effort to resolve its fight with the Pentagon (Axios) OpenAI updates its Codex desktop app with features like computer control, an in-app browser, image generation, automation memory, plugin support, and more (ZDNet) Sources: DeepSeek is in talks to raise outside capital for the first time, seeking at least $300M at a valuation of at least $10B (The Information) Longreads India produces 1.5M+ CS graduates annually, but AI coding tools are forcing its $315B IT outsourcing industry into an existential reckoning (Bloomberg) Doug Liman's $70M movie Bitcoin: Killing Satoshi uses AI for sets, lighting, and more in post-production, cutting costs from an estimated $300M (The Wrap) Defunct startups are being liquidated for their Slack archives, Jira tickets, and email threads—operational exhaust that AI labs now treat as premium training data (Forbes) Learn more at liquid.trade/techbrew. Disclaimer: ● Initial 3 week subscription and 4 weeks of medication from $79 plus tax and $179 per month plus tax for 12 week subscription thereafter. Final pricing depends on program selection. ● Noom GLP-1Rx Program involves healthy diet, exercise and support. Individual results vary. Meds & personalization based on clinical need. Not reviewed by FDA for safety, efficacy, or quality. No affiliation with Novo Nordisk Inc., the only US source of FDA-approved semaglutide. Not available in all 50 US states ● Based on an analysis of self reported data from 1,254 engaged Noom users. Learn more about your ad choices. Visit megaphone.fm/adchoices

    Pharmacy Podcast Network
    Clearway Health, John Nosta, Perigon 360, and Psychedelics in Practice | TWIRx

    Pharmacy Podcast Network

    Play Episode Listen Later Apr 17, 2026 118:06


    TWIRx News: The FDA plans to remove 12 peptide bulk drug substances from Category 2 of the Section 503A compounding list after their nominations were withdrawn. For compounders, the key issue is that this change does not automatically make compounding these substances permissible, leaving pharmacies exposed to ongoing regulatory uncertainty until the FDA makes further decisions. A nationwide Class II recall has been issued for Xanax XR 3 mg tablets in 60-count bottles, lot 8177156, after the product failed dissolution testing. Pharmacists should immediately locate and quarantine affected stock while reminding patients not to stop benzodiazepine therapy suddenly without direction from a healthcare provider. Community pharmacies are taking on a larger role in wound care by serving as an accessible first point of contact for patients with minor injuries. Pharmacists can help assess wounds, recommend appropriate over-the-counter treatment, watch for warning signs of complications, and refer patients for higher-level care when needed. Special sponsor interview with Allison Arant with Clearway Health.  Featured interview with  the World's Leading Innovation Theorist John Nosta Guests & sponsors of today's TWIRx, Perigon 360 Pharmacy with Chris Antypas PharmD and ed Mills  And a bonus interview with Dr. Andy Krut PharmD, on Psychedelics (e.g., LSD, psilocybin, DMT)

    Badlands Media
    MAHA News [4.17] New CDC Director, Peptides Deregulated, Big USDA Crop Buys, MAHA Infighting

    Badlands Media

    Play Episode Listen Later Apr 17, 2026 62:16


    Jordan Sather and Nate Prince are back from a week off and wasting no time. Trump has nominated Dr. Erica Schwartz as the new CDC director, and the MAHA world is already split on whether that's a win or a wolf in sheep's clothing. Kennedy is deregulating a list of peptides that had been quietly shoved into an FDA regulatory black hole since 2023, which means your BPC-157 can finally breathe again. The USDA is spending $60 million on real food for Americans (yes, actual fruit and chicken, not Froot Loops), and Joel Salatin is out here pitching Trump a "food emancipation proclamation." Meanwhile, cracks are showing inside the MAHA coalition as Dr. Malone takes aim at both RFK Jr. and FDA chief Marty Makary. It is a full plate of wins, drama, and cautious optimism from your favorite health freedom news desk.

    The Smart Weight Loss Coaching Podcast
    152. Foundayo (Orforglipron) Is Here! The Weight Loss Pill You've Been Waiting For Just Got FDA Approved

    The Smart Weight Loss Coaching Podcast

    Play Episode Listen Later Apr 17, 2026 21:18


    Back in Episode 118, Dr. Lisa introduced you to orforglipron, a promising weight loss pill that was still awaiting FDA approval. Well, the wait is officially over. The FDA just approved Foundayo (orforglipron), a once-daily GLP-1 pill for weight loss.Dr. Lisa covers:What Foundayo is, how it works, and what makes it different from other GLP-1 medicationsClinical trial results: how much weight loss to expectHow Foundayo compares to the Wegovy pillExactly how to take it (including what to do if you miss a dose)Side effects, safety information, and who should NOT take this medicationWho qualifies, and an important note for parents of teensCurrent pricing for self-pay, insured, and Medicare patientsWhy taking medication for weight loss is never "the easy way out"Thanks for listening! If you'd like more support on your weight loss journey, sign up for our free newsletter or check out our program at SmartWeightLossCoaching.com. And if this episode resonated with you, please share it with someone who's been looking for a needle-free weight loss medication option. We would love to help you reach your happy weight, and transform the way you talk to yourself about your body and the number on the scale. Negative thoughts about yourself don't have to take up so much brain space, and we'd be honored to help you reframe those thoughts. Also…We'd be grateful if you'd follow us and share our podcast with your friends & family. We're here to help you improve your health, live longer, healthier, and lose weight the SMART way! This episode was produced by The Podcast Teacher: www.ThePodcastTeacher.com.The Smart Weight Loss Coaching Podcast is for informational purposes only and does not constitute medical advice. Always consult your physician or a qualified healthcare provider before starting, stopping, or changing any medication.

    Mind Pump: Raw Fitness Truth
    2837: The Methylene Blue Masterclass: Cutting-Edge Mitochondrial Support with Dr. Scott Sherr

    Mind Pump: Raw Fitness Truth

    Play Episode Listen Later Apr 16, 2026 81:16


    This is one of the BEST interviews we've ever done on supplements and cutting-edge supplement technology... We had Dr. Scott Sherr on the podcast — a board-certified internal medicine physician who practices health optimization medicine and hyperbaric oxygen therapy. This guy KNOWS his stuff and we break down some of the most powerful compounds you can get your hands on to improve cognitive function, athletic performance, and longevity. Here's the reality... 94% of US adults are metabolically UNHEALTHY. That means your mitochondria — the powerhouses of your cells — are struggling to produce the energy you need. Dr. Sherr explains exactly why this happens, how it connects to everything from anxiety and depression to fat loss struggles, and what you can actually DO about it. We dive DEEP into methylene blue — the first drug ever registered with the FDA back in 1897 — and why it's become one of the most powerful tools for supporting mitochondrial function and energy production. But it doesn't stop there... We cover the GABAergic system and why most people are walking around GABA deficient (hello anxiety, insomnia, and mood issues), the synergy between methylene blue and red light therapy, how to use these compounds for travel, and a complete sleep optimization stack that could finally get you those 90+ Oura Ring scores. If you're tired of being tired, stressed about being stressed, or just want to understand how to actually support your body at a cellular level — this episode is a MUST listen. MAPS PPL — https://mapsppl.com (code: ppl) SPONSORS Troscriptions — https://troscriptions.com/mindpump (code: mindpump) Seed — https://seed.com/mindpump (code: 25mindpump) 00:00 — Intro 5:56 — Dr. Scott Sherr's background and health optimization medicine framework 10:42 — Strengths and weaknesses of conventional vs alternative medicine 16:34 — Why 94% of US adults are metabolically unhealthy 22:30 — The 'sympathetic spiral of doom' and why doing MORE isn't better 25:48 — Deep dive into methylene blue — history and mechanisms 35:09 — MAO inhibition, serotonin syndrome risk, and dosing protocols 42:43 — Methylene blue and red light therapy synergy 48:55 — GABA system, B3-GABA, and the TroCalm formula explained 59:58 — Complete sleep optimization stack and nighttime routine 67:30 — Cordycepin benefits and immune support protocols PEOPLE MENTIONED Dr. Scott Sherr — Guest — board-certified internal medicine physician, health optimization medicine practitioner, co-founder of Troscriptions Dr. Ted Achacoso — Founder of Troscriptions and the Health Optimization Medicine nonprofit, mentor to Dr. Sherr Alan Sherr — Dr. Sherr's father — chiropractor for 45+ years who influenced his alternative medicine philosophy Francisco Gonzalez Lima — Researcher at University of Texas Austin studying methylene blue for Alzheimer's, TBI, and stroke Thomas DeLauer — Mutual friend who uses methylene blue 2-3 times per week on high-stress days Paul Stamets — Referenced regarding mushroom knowledge and Amanita Muscaria/Santa Claus connection

    Infertile AF
    Listen Again: Dr. Natalie Crawford on Pregnancy Loss, Navigating Infertility as a Doctor, and Her New Book, The Fertility Formula

    Infertile AF

    Play Episode Listen Later Apr 16, 2026 44:17 Transcription Available


    On this week's episode, Ali sits down with an icon and true pioneer in the infertility space: double board-certified REI and infertility warrior, Dr. Natalie Crawford. Natalie opens up about her own journey through four pregnancy losses before welcoming her two children—and what it's like to be on both sides of the stirrups as both doctor and patient. She shares the unique challenge of navigating infertility as someone who “knows too much,” and how that knowledge can be both empowering and overwhelming. They also talk about how Natalie has built a massive, trusted community by showing up authentically on social media, why she decided to break away and co-found her boutique clinic, Fora Fertility in Austin, Texas, and what it really took to start her own thing.Plus, Natalie shares insights from her new book, The Fertility Formula—including how to advocate for yourself in the exam room, what her patients taught her along the way, and what she wants every fertility patient to hear right now.For more, and to order The Fertility Formula, visit www.nataliecrawfordmd.comIG: @nataliecrawfordmdEPISODE SPONSORS: THE WORK OF ART BOOK SERIESAli's Children's Book Series about IVF, IUI and Family Building Through Assisted Reproductive Technology https://www.infertileafgroup.com/booksThe 3-book bundle is now just $49 (normally $79)!The latest book in the Work of ART series, “You Are a Work of ART," is for every kiddo born through ART -- and the people who love them.PHERDALIG: @pherdal_sciencePherDal is the world's first and only FDA-cleared, sterile, at-home insemination kit designed to help people build their families in the comfort of home. Created by parents who've been there, PherDal is safe, simple, and affordable—putting more options in your hands as you grow your family. Explore at PherDal.com.Go to PherDal.com today and use code INFERTILEAF for $10 off.BELIIG: @belibabywww.belibaby.com Are you thinking about growing your family? Whether you're just starting to plan or are actively trying to conceive, preconception health is key. Beli has vitamins to help both women and men optimize their health before pregnancy. With essential nutrients like Folate, Iodine, and Zinc, Beli ensures your body is ready for this exciting next step. Give yourself and your future baby the best foundation for a healthy start.Visit Belibaby.com today and use code IAF15 for 15% off your first order. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

    The Bid Picture - Cybersecurity & Intelligence Analysis
    485. Latifa Seini

    The Bid Picture - Cybersecurity & Intelligence Analysis

    Play Episode Listen Later Apr 16, 2026 61:40 Transcription Available


    Check out host Bidemi Ologunde's new show: The Work Ethic Podcast, available on Spotify and Apple Podcasts.Email: bidemiologunde@gmail.comIn this episode, host Bidemi Ologunde sits down with entrepreneur Latifa Seini to explore the journey behind Lembrih, a platform rooted in African creativity, ethical commerce, and community impact. Drawing from her West African background and founder experience, Latifa reflects on what inspired her to build beyond traditional marketplaces, how she uses social media and digital tools to grow visibility and trust, and what it means to create a business with both cultural and economic purpose. How do you turn heritage into innovation? What does it take to build technology that truly serves artisans and small brands? And how can founders balance ambition, identity, and impact while building for the future?Sponsors and partners:Promeed: 100% mulberry silk pillowcases and bedding that feel incredibly soft, stay breathable, and are naturally gentle on hair and skin.SurviveX: professional-grade FSA/HSA eligible first aid and preparedness kits designed in Virginia, USA and produced in an FDA-registered facility.Alison US CA: Alison is the world's largest free online learning and skills-training platform, helping more than 50 million learners in 193+ countries build career-ready skills with 6,000+ free courses, certificates, and diplomas.eSign (iOS only): eSign is a clean, privacy-first document-signing app that works entirely on your device, letting you sign PDFs, DOCX files, images, and scans, edit and assemble pages, and export crisp 300 DPI PDFs in seconds, without accounts, cloud uploads, or compromising sensitive documents.Support the show

    Think Out Loud
    Why some researchers are editing human genes in embryos

    Think Out Loud

    Play Episode Listen Later Apr 16, 2026 15:37


     In 2023, the FDA approved the first gene therapies to help treat people with sickle cell disease. The treatment is for patients 12 years and older, but what if you could use this technology before someone is born? That’s what some researchers, and others, believe is the hope for the future. The idea is to use CRISPR, a technology used to edit the genes of living beings, during in vitro fertilization. It is much easier said than done, but could be possible in theory. Ashley Smart is the associate director of the Knight Science Journalism Program at MIT. He is also a senior editor at Undark and reported on embryonic gene editing for the publication. He joins us to share how these treatments and technologies might work, as well as the current challenges and limitations.

    Commune
    Is This Right for Me? Peptides: BPC-157, Growth Hormones and the Gray Market

    Commune

    Play Episode Listen Later Apr 15, 2026 39:55


    In March 2026, the largest gray-market peptide vendor in the U.S. went dark overnight. No refunds, and a wave of uncertainty about what these products actually are, how they're sourced, and whether they're worth the risk.In this episode, Jeff works through what peptides actually are, where the science holds up and where it doesn't, and what the gray-market collapse means for anyone paying attention to this space. Topics covered: BPC-157, CJC-1295, ipamorelin, and TB-500: what the research actually shows Why are oral peptide capsules mostly expensive amino acids The sourcing landscape: FDA-approved, compounding pharmacies, and gray market Who peptide therapy may be right for, and who should wait Free, evidence-backed alternatives for GH optimization and injury recovery This episode is for anyone who's been curious about peptide injections and wants the honest answer, not the Joe Rogan version. This episode was made possible by: Sunlighten:  Visit sunlighten.com/commune  Up to 2,100 off saunas and $50 off Red Light Products with code “COMMUNE” Bon Charge: Get 15% off when you order at boncharge.com and use promo code COMMUNE Stemregen: Get 20% off your first order at stemregen.co/commune with the code COMMUNEPOD Vivobarefoot: Try Vivobarefoot risk-free with a 100-day return guarantee, and get 15% off your order at vivobarefoot.com/commune. Beyond Biohacking: Save $400 on any ticket with code COMMUNE400 at beyondconference.com.

    DH Unplugged
    DHUnplugged #798: Market Immunity

    DH Unplugged

    Play Episode Listen Later Apr 15, 2026 61:08


    PCE and inflation trends – single day concern Earnings Season – Goldman, JPM Eco Reports of historic proportion Feds looking at Private Credit holdings at banks PLUS we are now on Spotify and Amazon Music/Podcasts! Click HERE for Show Notes and Links DHUnplugged is now streaming live - with listener chat. Click on link on the right sidebar. Love the Show? Then how about a Donation? Follow John C. Dvorak on Twitter Follow Andrew Horowitz on Twitter Warm-Up - Walking back - Waffling and Extensions --- Blockade - not really - Market Immunity - Jesus.ai - Reading Retreats (The New Silent Disco?) Markets - PCE and inflation trends - single day concern - PPI revised - Earnings Season - Goldman, JPM - Historic Eco Report - Feds looking at Private Credit holdings at banks CONGRATS RORY! - back-to-Back Masters Champ - Over $250M in tour winnings Market Update - Great week for markets as Operation obliteration is postponed - - Weekend concerns and opening in the RED Monday as we get clarification - Markets somewhat immune? Looking past? - FWIW: Not much is moving thought the Straight....But who cares! ----- Markets made back all of the losses from the War! Nothing to worry about... Historic! - As of this month, we have officially hit a new historical floor. - The preliminary University of Michigan Consumer Sentiment reading for April 2026 came in at 47.6, which is the lowest recorded value in the survey's 70-plus-year history. Consumer Sentiment Fed Looking - The Federal Reserve is asking major US banks for details about their exposure to private credit due to a surge in redemptions and a rise in troubled loans in the industry. - The Fed's queries are intended to assess the level of stress in the private credit industry and the potential for it to spill over to the wider financial system. - The Treasury Department is also questioning the insurance industry about exposures to private credit, as part of a broader regulatory push to get a handle on the scale of the strains in the $1.8 trillion private credit industry. ECO - PPI - PPI: Rose 0.5% month-over-month in March, well below the 1.2% consensus expectation -  Follows a downwardly revised 0.5% increase in February (from 0.7%) Core PPI (excluding food and energy): - Increased 0.1% in March, below the 0.4% consensus expectation - Follows a downwardly revised 0.3% increase in February (from 0.5%) --- Market talk: -- -  Final demand services were unchanged, giving markets room to look through the energy-driven spike as likely temporary Meanwhile... - Dow Inc. and Exxon Mobil Corp. are among the companies boosting prices for plastics as the sector grapples with supply shocks from the US-Israeli war on Iran. - The company said Monday that it will raise prices for North American buyers of polyethylene resins — common plastics found in packaging, films and containers — through at least May, according to a document viewed by Bloomberg. - That increase includes a 30-cent-per-pound boost for April and plans for another 20-cent-per-pound hike next month, according to the notice. Blockade - President Donald Trump said the US will begin a full naval blockade of the Strait of Hormuz and threatened to retaliate in the event of Iranian resistance. -The US and Iran failed to reach a deal in direct talks in Pakistan due to differences over the nuclear issue, according to Trump. --- At first, it was a FULL blockade - then another walk-back (or is this just politics vs reality?) - The blockade will be enforced impartially against vessels of all nations entering or departing Iranian ports and coastal areas, according to US Central Command. Goldman Earnings - Reports Q1 (Mar) earnings of $17.55 per share, $1.08 better than the FactSet Consensus of $16.47; revenues rose 14.4% year/year to $17.23 bln vs the $16.99 bln FactSet Consensus. - Net revenues in Fixed Income, Currency and Commodities were $4.01 billion, 10% lower than the first quarter of 2025, reflecting lower net revenues in FICC intermediation, due to significantly lower net revenues in interest rate products and mortgages and lower net revenues in credit products, partially offset by significantly higher net revenues in commodities and currencies. - Provisions for the first quarter of 2025 primarily reflected net provisions related to the credit card portfolio, which was transferred to held for sale in the fourth quarter of 2025. --- Goldman is cleaning up and selling off some of the credit card portfolio (Apple Card) ---- We discussed that analysts had been raising guidance for companies into the print. GS rallied 16% since March - so maybe just sell-the-news event Stocks: Earnings - Goldman Sachs downgraded Best Buy to a sell, and the stock dropped about 4% on the news. --- Goldman's view is that while Best Buy should get a short?term boost in the first quarter—helped by people pulling forward PC purchases and getting bigger tax refunds—that strength may not last. --------According to the analysts, once higher memory costs start working their way into laptop and computer prices, sales could come under pressure after Q1. Blackrock Call - Asset management giant BlackRock has raised its outlook for U.S. stocks, reasoning that contained impacts from the Iran war and strong corporate earnings will create a favorable backdrop. - With earnings season just getting underway, S&P 500 companies are expected to post a collective 12.6% profit increase for the first quarter. - But do we care what Blackrock says? Long only shop with $14T in ETFs Stocks: Monday/Tuesday -----Cruise line stocks were under pressure as higher energy costs and renewed concerns about demand came back into focus. Carnival dropped about 4%, Norwegian Cruise Line was down roughly 3%, and Royal Caribbean slid more than 2%. -----Airlines moved lower for similar reasons. Rising jet fuel prices and softer demand expectations weighed on the group, with United Airlines falling more than 2.5%, while Southwest and Delta both declined around 2%. --Tuesday - Follow through getting us at/above pre-war levels Stocks: Mattress Consolidation: - Leggett & Platt jumped about 9% after announcing it will be acquired by Somnigroup International, a bedding manufacturer. The deal is an all-stock transaction valued at roughly $2.5 billion, and it's expected to close by the end of 2026. ----Mattress Monopoly Now? Adding to  - Tempur Sealy, Mattress Firm, Dreams Stocks - Upgrades - Toll Brothers, Pultegroup — Shares of both stocks rose more than 1% after Evercore ISI upgraded the two homebuilders to outperform. - - The investment firm said it's time to buy the dip in the companies, believing the bad news is already priced in and that both Toll Brothers and Pultegroup could manage macroeconomic headwinds better than some of their peers. Pope Leo - WEAK on crime and terrible for Foreign Policy say President Trump -- Is the Pope involved in criminal /  police issues ? Jesus Update - Aside from the Jesus imagery with Trump as Jesus this weekend (Trust social post - then deleted) - At $1.99 per minute, the tech company Just Like Me is taking that concept to talk to Jesus to a new level. -----Users of the platform can join video calls with an avatar of Jesus generated by artificial intelligence. ------- Like other religious AI tools on the market, it offers words of prayer and encouragement in various languages. ----------With the occasional glitch, it remembers previous conversations and speaks through not-quite-synced lips. Reading Retreats - What it is: Paid reading retreats where people travel to quiet, upscale settings to read their own books—mostly in silence—alongside strangers. - The price: Typically $1,000+ for a long weekend, often selling out months in advance. - Why it works: People are burned out by screens and distractions and are paying for structure, silence, and protected time to focus. - Social without pressure: It offers light community—being alone together—without forced conversation or networking. - Cultural tailwinds: Fueled by BookTok, wellness travel, and nostalgia for slower, analog experiences, turning reading into a premium lifestyle activity. Of Interest - Delta Air Lines said Wednesday it will “meaningfully reduce” its capacity growth plans in the near term. AFTER BULLISH COMMENTS DAYS EARLIER - Delta joined United and JetBlue in hiking its checked bag fees this week as jet fuel costs surge. PRICE WILL NEVER COME DOWN - Delta said its fuel bill will be $2 billion higher this quarter because of the spike in costs. - The carrier also reported first-quarter earnings that beat analysts' expectations. BY THE WAY>>>>> JAYNA - AKA China - China's factory?gate prices rose 0.5%, the first increase in more than three years. -  Consumer prices increased 1% year over year in March, falling short of economists' expectations. - Gasoline prices jumped 11.1% from the prior month, even as Beijing tried to limit fuel price increases. - Economists warn the spike in input costs could lead to “bad inflation,” putting added pressure on manufacturers that are already operating with thin margins. Health Breakthrough - Revolution Medicines said its pancreatic cancer drug daraxonrasib succeeded in a Phase 3 trial. - RevMed said its drug almost doubled the typical length of survival and slashed the risk of death by 60% versus chemotherapy. - The company said it will soon seek FDA approval using a Commissioner's National Priority Voucher, which grants a quicker review. - It is a small?molecule oral oncology drug, taken as a daily pill, not chemotherapy or immunotherapy. - Stock up nicely on the news... China PPI - China's factory-gate prices rose for the first time in more than three years while consumer inflation moderated in March, amid a surge in oil prices as the Iran war upended global energy markets. - The producer price index grew 0.5% from a year earlier, the first growth since September 2022, ending the longest deflationary streak in decades. For the first quarter, the PPI fell 0.6% year on year. China PPI and CPI Intel - Intel's stock had a ninth straight winning day on Monday, up 58% over that stretch. - Shares of the semiconductor company are soaring after a series of announcements and major partnerships with Google and Elon Musk. - CPUs are seeing a resurgence as agentic artificial intelligence continues to gain traction.   Love the Show? Then how about a Donation? THE CLOSEST TO THE PIN for NETGEAR Winners will be getting great stuff like the new "OFFICIAL" DHUnplugged Shirt!     FED AND CRYPTO LIMERICKS   See this week's stock picks HERE Follow John C. Dvorak on Twitter Follow Andrew Horowitz on Twitter

    Techmeme Ride Home
    Space Race Acquisition

    Techmeme Ride Home

    Play Episode Listen Later Apr 14, 2026 20:41


    Amazon's dropping $10.8 billion on Globalstar to beef up its Leo satellite network and challenge Starlink — and Apple's along for the ride. Plus, federal charges for the Sam Altman attacker, OpenAI acqui-hires a fintech startup, Google declares war on back button hijacking, data labeling startups are printing money, and Missouri voters revolt over a data center. Amazon agrees to acquire satellite operator Globalstar for $10.8B to expand Leo satellite network; Amazon and Apple say Leo will power some iPhone and Watch services (Amazon) Amazon to Acquire Globalstar in Satellite Cellular-Connection Push (WSJ) US DOJ charges Daniel Moreno-Gama, accused of throwing a Molotov cocktail at Sam Altman's home, with attempted murder and arson (CNN) Man who attacked OpenAI CEO's home had list of other AI executives (NYT) OpenAI acquires personal finance startup Hiro Finance (TechCrunch) Google designates "back button hijacking" as malicious, sites could be demoted in Search from June 15 (9to5Google) Data labeling startup Handshake's gross annualized revenue hits ~$1B; Mercor also at $1B+ pace (The Information) Voters in Festus, Missouri oust all four incumbent council members days after council approved a $6B data center (Politico) Learn more at liquid.trade/techbrew. Disclaimer: ● Initial 3 week subscription and 4 weeks of medication from $79 plus tax and $179 per month plus tax for 12 week subscription thereafter. Final pricing depends on program selection.● Noom GLP-1Rx Program involves healthy diet, exercise and support. Individual results vary. Meds & personalization based on clinical need. Not reviewed by FDA for safety, efficacy, or quality. No affiliation with Novo Nordisk Inc., the only US source of FDA-approved semaglutide. Not available in all 50 US states● Based on an analysis of self reported data from 1,254 engaged Noom users. Learn more about your ad choices. Visit megaphone.fm/adchoices

    Cleared Hot
    350 Ops, 200 Bites, and the Future of Healing | Bill Clark & Dr. Bob Harmon | Ep. 442

    Cleared Hot

    Play Episode Listen Later Apr 13, 2026 170:58


    Bill Clark is a former DEVGRU military working dog handler — one of the first brought into the program when it launched around 2002. He grew up in chaos. His father was a Vietnam-era Marine door gunner. His mother married five times. His stepfathers were abusive. He played Division I football, joined the Marines, switched to the Navy for a dog handler slot, and ended up spending 13 years at the command across 13 deployments. He ran over 350 operations and logged more than 200 bites. He survived late-stage colon cancer at 37 — linked to battlefield exposures — and now leads executive protection for Ethereum co-founder Charles Hoskinson, who is building what may become the largest stem cell treatment hub in America at his clinic in Gillette, Wyoming. Dr. Bob Harmon calls himself a cow doctor. He started as a large-animal veterinarian out of UC Davis, got pulled into doing clinical trials for pharma companies, and then one day watched stem cells beat like a heart in a petri dish — no electrical stimulation, just cells that had been told what to become. That moment changed the trajectory of his career. He built a veterinary stem cell company that has now treated over 25,000 patients across 60 species. He developed stem cell therapy for the Navy's dolphins and sea lions. And he became the first person in the history of biopharma to take only veterinary data to the FDA and get approval for a human clinical trial. His company, Personalized Stem Cells, is now treating humans under the Federal Right to Try Act and the newly signed Wyoming Stem Cell Freedom Act. We talk about the night Bill's dog Axe took a round through the skull and kept trying to get back in the fight. What it looks like to laze a door from 300 yards and send a dog into a compound full of armed fighters. How big pharma's animal and human divisions refuse to talk to each other. Why your own fat holds young stem cells at any age — even at 92. The difference between your own cells and donor cells. The ten COVID ICU patients who all walked out. How stem cells make their own morphine-like painkiller and could break the opioid addiction cycle. The TBI pilot study coming for veterans. And what it would take to get stem cells on the sideline of an NFL game or in a medic's backpack on the battlefield.  https://www.personalizedstemcells.com/   Today's Sponsors:  Black Rifle Coffee: https://www.blackriflecoffee.com   David: David is offering our listeners a special deal: buy 4 cartons and get the 5th free when you go to https://www.davidprotein.com/CLEAREDHOT   

    The Peter Attia Drive
    #387 - AMA #83: Peptides—evaluating the science, safety, and hype in a rapidly growing field

    The Peter Attia Drive

    Play Episode Listen Later Apr 13, 2026 22:01


    View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this "Ask Me Anything" (AMA) episode, Peter explores the topic of gray-market peptides, one of the most requested and most confusing topics he's covered on The Drive. Peptides sit at the intersection of biological plausibility, clinical promise, and aggressive commercialization, and are often marketed as cutting-edge therapies for everything from muscle repair and longevity to cosmetic enhancement. Rather than promoting or dismissing peptides wholesale, Peter lays out a clear, repeatable framework for evaluating any peptide or drug—covering mechanism, intended effects, safety, dosing, and alternatives. He distinguishes FDA-approved peptide therapeutics from the loosely regulated "peptides" common in biohacking culture; examines the strengths and limitations of animal and human evidence; unpacks manufacturing, gray-market sales, "research use only" labeling, and third-party testing; addresses oral peptides and absorption challenges; and explains how patents and incentives shape which compounds advance through clinical pipelines. The discussion concludes with a sober look at what would need to change for peptides to become broadly usable therapies, where legitimate peptide therapeutics may expand next, and which areas of medicine stand to benefit most right now. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #83 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: Setting the framework for evaluating peptides, and explaining the goal of this discussion [3:15]; What peptides are: basic definitions, biological roles, and therapeutic foundations [5:30]; A framework for evaluating peptides: mechanism, evidence, safety, and regulatory context [10:00]; Peptide case study—SS-31: mechanism of action, approved use in Barth syndrome, and other claimed effects [18:15]; Does the mechanistic rationale for SS-31 translate into measurable benefits? [22:15]; SS-31 continued: safety considerations, gray market risks, the balance of risk versus reward, and why it belongs in bucket #3 [26:00]; Peptide case study—melanotan-II: claimed effects, mechanism of action, safety, and side effects [30:45]; Melanotan-II continued: weighing the potential risks versus benefits and why it belongs in bucket #2 [36:30]; Peptide case study—CJC-1295: growth hormone–stimulating mechanism, claimed effects, and limited human data [40:15]; CJC-1295 continued: dosing uncertainty, risk-reward analysis, lack of long-term safety data, limited approved options, and why it belongs in bucket #2 [49:30]; Peptide case study—BPC 157: uncertain origins, broad claims, and weak mechanistic evidence [57:45]; BPC 157 continued: review of human evidence, lack of replication of animal data, safety considerations, risk-reward analysis, and why it belongs in bucket #1 [1:03:15]; Other popular "gray market" peptides and why they mostly fail when under scrutiny [1:11:15]; How the evidence on peptides compares to rapamycin, and why the lack of data is the biggest concern [1:20:00]; Understanding peptide regulation: FDA approval, supplement oversight, and the risks of gray-market compounds [1:23:00]; Inside the gray market: how peptides are sold, regulated, and why testing cannot guarantee safety [1:26:45]; Limitations of oral peptides, and examples of peptides in bucket #4 [1:31:45]; The future of peptides: real therapeutic potential versus hype in the wellness market [1:35:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

    Relatable with Allie Beth Stuckey
    Ep 1331 | Ron Answers Your Questions About Iran, Autism, and Birthright Citizenship

    Relatable with Allie Beth Stuckey

    Play Episode Listen Later Apr 11, 2026 58:14


    Allie's dad, Ron Simmons, sits in the host's chair to give his insight into the conflict with Iran and if Iran is hiding enriched uranium to create a nuclear weapon. In honor of Autism Awareness Month, Ron covers FDA studies of possible treatments for autism and the challenges of raising a child with special needs. Finally, Ron answers some viewer questions ranging from fears of WWIII and gas prices to child discipline, parenthood, and finances. Share the Arrows 2026 is on October 10 in Dallas, Texas! Tickets are on sale now at: ⁠⁠⁠⁠⁠⁠https://sharethearrows.com⁠⁠⁠ Share the Arrows is sponsored by: A'del Natural Cosmetics: AdelNaturalCosmetics.com Range Leather: RangeLeather.com/ALLIE We Heart Nutrition: WeHeartNutrition.com Buy Allie's book "Toxic Empathy: How Progressives Exploit Christian Compassion": ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.toxicempathy.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ – Time Codes 0:00 Introduction 3:00 Iran War Update 33:37 Autism Awareness Month 44:12 Viewer Q & A – Episodes You May Like: Prophecy Fulfilled? Iran Strikes & the End Times | Ep 1312 https://www.youtube.com/watch?v=NOQvlwqs-Sg&t=2691s This is a War Against Radical Islam, not Just Iran | Ron Simmons | Ep 1314 https://www.youtube.com/watch?v=f93ttHx2jsg&t=1s Autism Isn't a Superpower — or a Dead-End. A Story of Tough Love | Leland Vittert | Ep 1282 https://www.youtube.com/watch?v=irveYUNOcVk&t=735s --- ► Buy Allie's book, "You're Not Enough (& That's Okay): Escaping the Toxic Culture of Self-Love": https://alliebethstuckey.com/book ► Subscribe to the podcast: iTunes: https://apple.co/2UVssnP Spotify: https://spoti.fi/2FwkXxj ► Connect with Allie on social media: https://twitter.com/conservmillen https://www.instagram.com/alliebstuckey/ https://facebook.com/allieBlazeTV/ ► Relatable merchandise – use promo code 'ALLIE10' for a discount: https://shop.blazemedia.com/collections/allie-stuckey

    The Megyn Kelly Show
    Who Will Be Next Attorney General, Diddy Appeals Sentence, New Dog Longevity Drug: AM Update 4/10

    The Megyn Kelly Show

    Play Episode Listen Later Apr 10, 2026 18:03


    As the Iran ceasefire enters day three, oil traffic through the Strait of Hormuz remains severely disrupted and Israeli strikes in Lebanon continue, underscoring how fragile and contested the agreement remains. A behind-the-scenes battle for control of the Justice Department intensifies as President Trump weighs key allies for Attorney General amid internal divisions and high-profile legal stakes. Sean “Diddy” Combs' legal team challenges his sentence in federal appeals court, arguing it was excessive and floating a First Amendment defense that judges appear unconvinced by - MK True Crime Host Phil Holloway weighs in. A new daily pill designed to extend dogs' lifespans moves closer to FDA approval, with researchers eyeing potential breakthroughs for human aging next.   Cozy Earth: Celebrate Mom with the ultimate gift of comfort by using code MEGYN at https://cozyearth.com   Done with Debt: https://www.DoneWithDebt.com & tell them Megyn Kelly sent you! Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    Verdict with Ted Cruz
    Bonus: Daily Review with Clay and Buck - Apr 7 2026

    Verdict with Ted Cruz

    Play Episode Listen Later Apr 8, 2026 65:58 Transcription Available


    Meet my friends, Clay Travis and Buck Sexton! If you love Verdict, the Clay Travis and Buck Sexton Show might also be in your audio wheelhouse. Politics, news analysis, and some pop culture and comedy thrown in too. Here’s a sample episode recapping four takeaways. Give the guys a listen and then follow and subscribe wherever you get your podcasts. Trust in Trump Clay Travis and Buck Sexton analyze Trump’s warning that Iran’s “civilization” could effectively end if its leadership refuses to comply with U.S. demands, particularly reopening the Strait of Hormuz and conceding on its nuclear program. The hosts explain that this hour centers on geopolitics, national security, global energy markets, and domestic political fallout, making it one of the most consequential foreign policy hours of the program to date. Throughout Hour 1, Clay and Buck break down Trump’s negotiating strategy with Iran, emphasizing his use of maximal pressure and rhetorical brinkmanship to extract leverage. They argue that Trump’s threats are designed to terrify Iranian leadership into compliance rather than signal an uncontrolled rush toward wider war. A major focus is the strategic importance of the Strait of Hormuz, which Iran has refused to reopen despite proposals for a temporary ceasefire. The hosts stress that the Strait is the critical choke point for global oil supply, and its continued closure threatens massive economic consequences, including higher gas prices, inflation, and rising consumer costs in the U.S. and worldwide. They repeatedly note that Trump’s top objective appears to be reopening the Strait to stabilize global energy markets, especially in an election year. The Red Line Clay firmly rejects claims circulating online that President Trump is preparing to drop a nuclear weapon on Iran, calling those assertions unserious and detached from reality. Clay and Buck note that financial markets—including oil prices and the stock market—remain relatively calm, underscoring their argument that investors and global observers broadly expect a diplomatic or limited military outcome rather than catastrophic escalation. They explain that markets often reflect collective judgment, and the lack of panic suggests confidence that Trump will avoid extreme actions while still applying pressure. Flat Earthers in Denial Clay and Buck pivot to a major positive development: the successful completion of the Artemis II mission. They highlight President Trump’s remarks congratulating the crew for traveling farther from Earth than any humans in history, circling the far side of the moon, and laying the groundwork for a permanent U.S. presence on the lunar surface and eventual missions to Mars. The hosts emphasize that Artemis II represents American innovation, national ambition, and a return to frontier‑driven leadership, framing space exploration as central to U.S. identity, technological advancement, and long‑term prosperity. Clay and Buck discuss the cultural importance of astronauts as one of the last broadly admired and bipartisan American “heroes,” contrasting public trust in astronauts with declining faith in other institutions. They also jokingly note how renewed space travel further undermines flat‑earth conspiracy theories, which leads into a more serious discussion about the growing incentive structure in media and social platforms that rewards misinformation, extremism, and conspiracy content regardless of truth or consequences. JFK Jr.: Take Back Your Health! An extensive interview with HHS Secretary Robert F. Kennedy Jr., who provides a detailed update on the MAHA (Make America Healthy Again) agenda. Kennedy outlines sweeping reforms underway at HHS, including requiring hospitals to serve real, nutritious food, removing petroleum‑based food dyes, reversing decades of industry‑driven dietary guidelines, addressing microplastics, ending animal testing, and restructuring the FDA’s “generally recognized as safe” loophole. He frames chronic disease as both a national health and national security crisis, citing childhood obesity, metabolic disease, and skyrocketing healthcare costs. Kennedy also addresses declining trust in public health institutions following COVID‑19, arguing that transparency, honesty, and acknowledging uncertainty are the only ways to rebuild credibility. He explains reforms aimed at reducing pharmaceutical prices through “most favored nation” pricing and highlights dramatic disparities between U.S. drug costs and European prices. A particularly timely discussion focuses on peptides and GLP‑1 medications, where RFK Jr. explains how Biden‑era FDA actions pushed widely used peptides into legal gray and black markets despite no documented safety signals. He argues for restoring regulated access so Americans are not forced to rely on unverified sources, emphasizing evidence‑based regulation over prohibition. 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