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DNA replication and repair in vertebrate cells

Play Episode Listen Later Aug 9, 2017 7:56


Dr Costanzo talks to ecancertv at IFOM EMBL about vertebrate genome stability, focusing on the DNA replication and repair in vertebrate cells. Additionally he discusses his research using extracts derived from Xenopus laevis eggs, which allow extensive biochemical analysis which can be reproduced in vitro complex cell cycle events such as chromatin formation, nuclear assembly, semi-conservative DNA replication, chromosome assembly and mitotic spindle formation.

Extreme diets and their beneficial effects during cancer treatment

Play Episode Listen Later Aug 9, 2017 10:07


Dr Longo talks to ecancertv at IFOM EMBL about his study of the positive effects of fasting, extreme diets and drugs that mimic them on the prevention and treatment of cancer.

Genetics and epigenetics of lymphocyte development and transformation

Play Episode Listen Later Aug 9, 2017 8:32


Dr Casola talks to ecancertv IFOM EMBL about his research to dissect the genetic basis for responsiveness/resistance of lymphomas to current therapies.

Control of migratory and invasive strategies in tumour cells

Play Episode Listen Later Aug 9, 2017 7:43


Dr Scita talks to ecancertv at IFOM EMBL about at his work looking at tumour cell migration and the ability of the tumour cells to use different motility modes to disseminate as well as allowing the cells to 'escape' pharmacotherapeutic intervention.

De-activating chromosomes to prevent cancer

Play Episode Listen Later Aug 9, 2017 6:04


Dr Avner talks to ecancertv at IFOM EMBL about his work looking at the epigenetic mechanisms that can lead to cancer and other diseases. His research seeks to understand why chromosome activation takes place and how they may be turned off to prevent their undesirable consequences.

New strategies to inhibit tumor angiogenesis

Play Episode Listen Later Aug 9, 2017 5:37


Dr Dejana talks to ecancertv at IFOM EMBL about her work on one of the innovative aspects of anti-cancer therapies, inhibiting tumour growth by blocking blood supply. Her study takes a particular focus on brain tumours that currently don't currently have a effective treatment method.

The control of genome integrity and their importance for the cell

Play Episode Listen Later Aug 9, 2017 3:08


Dr Foiani talks to ecancertv at IFOM EMBL about his study of the mechanisms which control chromosome integrity which in turn prevent genome instability and their pivotal importance for the cell.

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