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“They're kind of like a hidden superhero in your body and we just didn't know they existed. Muse cells eat the damaged cells, and they can actually turn into new cells using the cellular machinery.”Dr. Adeel Khan is a global thought leader in regenerative medicine. He is the CEO and Founder of and founder of Eterna Health, whose work with MUSE cell therapy—developed in collaboration with its discoverer, Professor Mari Dezawa—has made him the go-to expert for world leaders, athletes, and celebrities Chris Hemsworth, Kim Kardashian, and Tony Robbins. In this episode, we move beyond the hype of "anti-aging" to explore the hard science of Muse cells (Multilineage-differentiating Stress-Enduring cells). Dr. Khan breaks down how these unique cells differ from the "medicinal signaling cells" (MSCs) found in most clinics and how they act as a bridge to a future where tissue regeneration is standard care.(0:00) The "Repair Guys" & The Muse Difference Dr. Khan explains why traditional stem cells (MSCs) often disappoint and how Muse cells offer the "best of both worlds": safety and pluripotency.(2:19) Smart Cells: How They Find the Damage Understanding the "homing mechanism" that allows Muse cells to sense inflammation and instinctively travel to injured areas like the brain or heart.(3:11) Curing the Incurable: Diabetes & Alzheimer's The potential of the "cure triad"—stem cells, gene therapy, and FMT—to treat complex autoimmune diseases within the next decade.(4:40) Biological Noise & The Symphony of Health How "static" in our gene expression indicates aging, and how cellular therapy can reduce this noise to restore the body's harmony.(6:40) The Viral Monkey Study Dr. Khan discusses a recent study showing significant de-aging in monkeys through high-frequency cell dosing.(7:32) Unshakeable Foundations: Lifestyle as MedicineWhy advanced therapies must be paired with purpose, community, and mindfulness to create a "bulletproof" body.(8:44) From Sketchy to StandardizedNavigating the regulatory landscape: why Muse cells are being classified as a drug in regions like the UAE and the path toward FDA approval.(12:24) A Personal MissionDr. Khan shares the origin of his journey: trying to find solutions for his mother's chronic illness when traditional medicine failed.(14:16) The Cancer HunterUnlike other pluripotent cells that risk tumor growth, Muse cells have a unique mechanism that can detect cancer cells and trigger their death.(18:30)Future Outlook: AI, Nature & Blue Zones Reflections on the risks of AI, the importance of "Blue Zone" city design, and reconnecting with nature in a post-human world.Episode Websitewww.creativeprocess.info/podInstagram:@creativeprocesspodcast
"The repair mechanisms don't work as well as you get older... The whole idea was: if we can give you more of the 'repair guys,' maybe we can reverse disease."Dr. Adeel Khan is a global thought leader in regenerative medicine. He is the CEO and Founder of and founder of Eterna Health, whose work with MUSE cell therapy—developed in collaboration with its discoverer, Professor Mari Dezawa—has made him the go-to expert for world leaders, athletes, and celebrities Chris Hemsworth, Kim Kardashian, and Tony Robbins. In this episode, we move beyond the hype of "anti-aging" to explore the hard science of Muse cells (Multilineage-differentiating Stress-Enduring cells). Dr. Khan breaks down how these unique cells differ from the "medicinal signaling cells" (MSCs) found in most clinics and how they act as a bridge to a future where tissue regeneration is standard care.(0:00) The Future of Regenerative Medicine(6:13) The Muse Difference: Why these cells are "pluripotent" (able to become any tissue) without the cancer risks of Yamanaka factors.(10:29) Curing the Incurable: Diabetes & Alzheimer's (11:27) The Cure Triad: How combining stem cells, gene therapy, and Fecal Microbial Transplants (FMT) could cure complex autoimmune diseases within a decade.(12:56) Biological Noise: Measuring the "mistakes" in our gene expression to quantify aging.(16:42) Lifestyle as Medicine: Why Dr. Khan prescribes community, mindfulness, and nature immersion alongside advanced therapies.(18:13) From Sketchy to Standardized: The Regulatory Landscape(23:25) A Personal Mission: Trying to Save Mom(25:38) The Cancer Hunter: How Muse cells naturally detect and trigger cell death in tumors.(29:02) Quantum Biology & Healing Frequencies(41:13) The AI Pessimist: Planning for a Post-Human World(44:03) Reconnecting with NatureEpisode Websitewww.creativeprocess.info/podInstagram:@creativeprocesspodcast
In this episode of BioHackingVille, Rob Rene hosts Dr. Clinton Demaris from Well Within Chiropractic to discuss the intricate connections between emotional and physical health. The conversation highlights the role of stress, subconscious emotions, and trauma in chronic health issues. Dr. Deme explains the Neuro Emotional Technique (NET) and its effectiveness in treating psychological and physical ailments by addressing underlying emotional traumas. The episode also touches on various holistic health strategies, including nutritional supplements, chiropractic adjustments, and the importance of close personal relationships in overall health. The significance of dental health and its impact on systemic health is also discussed.00:00 Introduction and Disclaimer00:26 Welcome to Biohack01:22 Meet Dr. Clinton Deme03:05 Dr. Deme's Journey and Philosophy05:37 Understanding the Root Causes of Health Issues07:13 The Role of Emotional Stress in Health21:22 Exploring Muscle Testing25:36 Using Acupuncture for Diagnosis and Correction26:08 Understanding Conditioned Responses28:16 Identifying Root Causes of Emotional Triggers34:36 The Impact of Close Relationships on Health40:38 The Connection Between Dental Health and Overall Well-being47:25 The Importance of Addressing Emotional Health48:33 Conclusion and Final Though
What if neurons aren't the foundation of mind? In this Mind-Body Solution Colloquia, Michael Levin and Robert Chis-Ciure challenge one of neuroscience's deepest assumptions: that cognition and intelligence are exclusive to brains and neurons.Drawing on cutting-edge work in bioelectricity, developmental biology, and philosophy of mind, this conversation explores how cells, tissues, and living systems exhibit goal-directed behavior, memory, and problem-solving — long before neurons ever appear.We explore: • Cognition without neurons• Bioelectric networks as control systems• Memory and learning beyond synapses• Morphogenesis as collective intelligence• Implications for AI, consciousness, and ethicsThis episode pushes neuroscience beyond the neuron, toward a deeper understanding of mind, life, and intelligence as continuous across scales.TIMESTAMPS:0:00 – Introduction: Why Neuroscience Must Go Beyond Neurons3:12 – The Central Claim: Cognition Is Not Exclusive to Brains7:05 – Defining Cognition, Intelligence, and Agency Without Neurons11:02 – Bioelectricity as a Control Layer for Morphogenesis15:08 – Cells as Problem-Solvers: Goals, Memory, and Error Correction19:41 – The Body as a Cognitive System: Scaling Intelligence Across Levels24:10 – Developmental Plasticity and Non-Neural Decision-Making28:36 – Morphological Computation and Collective Cellular Intelligence33:02 – Challenging Neuron-Centric Neuroscience Assumptions37:18 – Bioelectric Networks vs Neural Networks: Key Differences41:55 – Memory Without Synapses: Storing Information in Living Tissue46:07 – Rewriting Anatomy: Regeneration, Repatterning, and Control50:29 – Cancer, Developmental Errors, and Cognitive Breakdown54:48 – Pluribus: Philosophical Implications59:14 – From Cells to Selves: Where Does Agency Begin?1:03:22 – Implications for AI: Intelligence Without Brains or Neurons1:08:11 – Rethinking Consciousness: Gradualism vs Binary Models1:12:47 – Ethics of Expanding the Moral Circle Beyond Humans1:17:31 – Future Science: New Tools for a Post-Neuron Neuroscience1:22:54 – Closing Reflections: Life, Mind, and Intelligence All the Way DownEPISODE LINKS:- Cognition All the Way Down 2.0: Neuroscience Beyond Neurons in the Diverse Intelligence Era: https://link.springer.com/article/10.1007/s11229-025-05319-6- Robert's Publications: https://scholar.google.com/citations?user=7V9C7skAAAAJ&hl=en- Mike's Podcast 1: https://www.youtube.com/watch?v=v6gp-ORTBlU- Mike's Podcast 2: https://www.youtube.com/watch?v=kMxTS7eKkNM- Mike's Podcast 3: https://www.youtube.com/watch?v=1R-tdscgxu4- Mike's Podcast 4 (with Terrence Deacon): https://youtu.be/HuWbHwPZd60?si=z2unvX37OjXMjjIv- Mike's Lecture: https://www.youtube.com/watch?v=aQEX-twenkA- Mike's Channel: https://www.youtube.com/@drmichaellevin- Mike's Website: https://drmichaellevin.org/- Mike's Blog: https://thoughtforms.lifeCONNECT:- Website: https://mindbodysolution.org - YouTube: https://youtube.com/@mindbodysolution- Podcast: https://creators.spotify.com/pod/show/mindbodysolution- Twitter: https://twitter.com/drtevinnaidu- Facebook: https://facebook.com/drtevinnaidu - Instagram: https://instagram.com/drtevinnaidu- LinkedIn: https://linkedin.com/in/drtevinnaidu- Website: https://tevinnaidu.com=============================Disclaimer: The information provided on this channel is for educational purposes only. The content is shared in the spirit of open discourse and does not constitute, nor does it substitute, professional or medical advice. We do not accept any liability for any loss or damage incurred from you acting or not acting as a result of listening/watching any of our contents. You acknowledge that you use the information provided at your own risk. Listeners/viewers are advised to conduct their own research and consult with their own experts in the respective fields.
Welcome to Season 2 of the Orthobullets Podcast.In this episode, we review the high-yield topic of Bone Cells from the Basic Science section.Follow Orthobullets on Social Media:FacebookInstagramTwitterLinkedInYouTube
Is your doctor lying to you about recovery? In this episode, I sit down with Dr. Tommy Rhee, the former team doctor for the Tampa Bay Buccaneers and a pioneer in regenerative medicine. We uncover the dark side of "traditional" pain management—why cortisone shots, ice, and pain killers might actually be accelerating your aging process and destroying your joints. We dive deep into the breakthrough science of "Zombie Cells" (Senescence), how to lengthen your telomeres to reverse biological aging, and the new topical stem cell technology (Regen) that is saving NFL careers without a single needle. If you are a man over 30 feeling the aches of aging, this episode is your roadmap to a pain-free life. CHAPTERS 0:00 - The "Pain Med" Trap: Why masking injury leads to rupture 02:17 - Who is Dr. Tommy Rhee? (NFL & UCLA Experience) 03:55 - Recovery vs. Overtraining: Why you feel old & tired 08:21 - The Truth About Cortisone & Injections (Secondary Injury) 10:32 - The "Regen" Breakthrough: Stem cells without needles? 14:39 - What are "Zombie Cells"? (The Science of Aging) 20:29 - Live Cells vs. Cell-Free: Safety & Cancer Risks Explained 26:49 - How to fix "Dad Knees" & Tennis Elbow 32:05 - WARNING: Stop taking pain meds before a workout 33:44 - The Future of Longevity: Active at 80 49:03 - Dr. Rhee diagnoses Ted's foot pain (Live Consult) Rhee's Links: Website: rheegen.com Practice: physicalchiro.com Instagram: dr.rheetommy Free eBook Here: Mastering Self-Development: Strategies of the New Masculine: https://rebrand.ly/m2ebook ⚔️JOIN THE NOBLE KNIGHTS MASTERMIND⚔️ https://themodernmanpodcast.com/thenobleknights
Dr. Michael Levin (@drmichaellevin) is the Vannevar Bush Distinguished Professor of Biology at Tufts University and director of the Allen Discovery Center. He is primarily interested in how intelligence self-organizes in a diverse range of natural, engineered, and hybrid embodiments. Applied to the collective intelligence of cell groups undergoing morphogenesis, these ideas have allowed the Levin Lab to develop new applications in birth defects, organ regeneration, and cancer suppression.This episode is brought to you by:ShipStation shipping software: ShipStation.com/TimAG1 all-in-one nutritional supplement: DrinkAG1.com/TimOur Place's Titanium Always Pan® Pro using nonstick technology that's coating-free and made without PFAS, otherwise known as “forever chemicals”: FromOurPlace.com/TimTIMESTAMPS:[00:00:00] Start[00:03:18] The Body Electric: A Vancouver bookstore discovery that launched a career.[00:04:19] Bioelectricity 101: Your brain uses it to think; your body used it before you had a brain.[00:06:05] The lesson learned by scrambled tadpole faces that rearrange themselves.[00:08:51] Software vs. hardware: The genome is your factory settings, not your destiny.[00:11:43] Two-headed flatworms: Rewriting biological memory without touching DNA.[00:16:20] Seeing memories: Voltage-sensitive dyes reveal the body's hidden blueprints.[00:20:12] Three killer apps for humans: Birth defects, regeneration, and cancer.[00:24:27] Cancer as identity crisis: Cells forgetting they're part of a team.[00:25:40] The boredom theory of aging: Goal-seeking systems with nothing left to do.[00:30:09] Planaria's immortality hack: Rip yourself in half every two weeks.[00:31:27] Manhattan Project for aging: Crack cellular cognition, everything else falls into place.[00:33:47] Giving cells new goals: Convince a gut to become an eye.[00:37:42] Must mammalian mortality be mandatory?[00:40:25] Cross-pollination: Why biologists would benefit from programming courses.[00:47:15] Does acupuncture actually do anything?[00:50:57] Placebo as feature, not bug: Words and drugs share the same mechanism.[00:55:06] The frame problem: Why robots explode and rats intuit what matters.[00:59:41] Binary thinking is a trap: “Is it intelligent?” is the wrong question.[01:07:46] Minimal brain, normal IQ: Clinical cases that break neuroscience.[01:08:45] Super panpsychism: Your liver might have opinions.[01:13:48] The Platonic space: Bodies as thin clients for patterns from elsewhere.[01:15:24] Keep asking “why” and you end up in the math department.[01:23:07] Polycomputing: Sorting algorithms secretly doing side quests.[01:28:24] Power scaling for the future and avoiding red herrings for understanding machine minds.[01:34:06] Sci-fi recommendations.[01:37:24] Cliff Tabin's toast and Dan Dennett's steel manning.[01:41:21] Parting thoughts.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
On today's episode, Andy sits down with former CIA Targeter Sarah Adams to discuss modern media, misinformation, and the current threat landscape. They focus on the Taliban and Al-Qaeda, how these groups are funded, and how information about them is reported and interpreted. She also hosts the new podcast The Watch Floor where she breaks down global news and emerging threats, helping everyday people stay informed, prepared, and ready. Change Agents is an IRONCLAD Original More from Sarah: YouTube - The Watch Floor: https://www.youtube.com/@thewatchfloor X: https://x.com/The_Watch_Floor https://x.com/sarahadams Chapters: (00:00) - Introduction (01:10) - The Next Attack? (01:20) - Overcoming Partisanship and New Podcast "The Watch Floor" (08:16) - Why the US is Funding the Taliban (13:58) - Politicians allowing the US to Fund the Taliban (20:30) - What Afghanistan Looks Like Now (27:34) - How Terror Organizations Recruit New Members (37:26) - The Rise of the Muslim Brotherhood (40:17) - The Next Attack (45:30) - Threats at the Northern Border Sponsors: Firecracker Farm Use code IRONCLAD to get 15% off your first order at https://firecracker.farm/ GHOSTBED: Go to https://www.GhostBed.com/CHANGEAGENTS and use code CHANGEAGENTS for an extra 15% off sitewide. Norwood Sawmills: Learn more about Norwood Sawmills and how you can start milling your own lumber at https://norwoodsawmills.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices
In this inspiring episode of The Recovery Vow Podcast, Eric sits down with "Recovery Jon," a social media influencer and advocate who turned a life of trafficking, addiction, and arrests into a platform that reaches millions. Jon opens up about the childhood trauma that severed his connection with God at age 12, leading to an anger-filled adolescence and a spiral into opiate addiction. He shares the harrowing reality of the opioid epidemic—from trafficking drugs across state lines to staring down the barrel of a gun and feeling nothing but apathy. Together, they discuss the moment of surrender in a holding cell that changed everything, the power of the 12 steps, and how Jon used social media to show the world that recovery is possible. This conversation is a powerful testament that no matter how far you fall—even if you end up in a jail cell instead of Yankee Stadium—God's plan for your life is bigger than your past. On This Episode: • The childhood trauma that led Jon to stop praying for years • From baseball dreams to the nightmare of opiate trafficking • The "gun to the head" moment and the apathy of addiction • The jail cell realization: "This is not Yankee Stadium" • How posting a "before and after" photo launched a movement • Finding a "spiritual bank account" and rebuilding self-worth • The full-circle moment of standing in center field at Yankee Stadium Connect with Jon: TikTok/Socials: @RecoveryJon Connect with us: Socials: @RecoveryVow Website: recoveryvow.com Email: recoveryvow@gmail.com New episodes each Monday! Top ways to support this podcast:
Scientists have frozen bodies. Heads. Cells. Embryos.But no human being has ever been revived after cryonic freezing.And yet… people keep doing it.Some of the most famous, intelligent, wealthy people in history chose to be frozen after death—not because it works, but because maybe someday it could.That alone tells us something important about the human heart.We don't just fear death. We fear finality.One of the most well-known examples is baseball legend Ted Williams. After his death, his body—specifically his head—was cryonically preserved. The idea wasn't that science could bring him back now, but that future technology might.......Ted WilliamsTomorrow BioCryonics
In this episode of the What Happens in Vagus podcast, Dr. Stephanie Canestraro sits down with nurse Emma Robertson to explore her journey from high functioning perfectionism to a full nervous system crash and eventual recovery. With a background in human anatomy and frontline healthcare, Emma shares both the clinical and deeply personal realities of living with dysautonomia and chronic nervous system dysregulation.Emma's symptoms began after graduating university and starting an intense nursing job that left her overworked, under fueled, and ignoring early warning signs like gut issues, rashes, and anxiety. Over time, a combination of stress, restrictive eating, nutrient depletion, and environmental and immune stressors pushed her system past its limit, leading to a sudden and frightening escalation of symptoms.She describes experiencing hyperadrenergic POTS, heart rhythm disturbances, constant panic, severe digestive dysfunction, blood sugar crashes, insomnia, dizziness, and exercise and heat intolerance. Many of her symptoms were misattributed to anxiety, leaving her feeling hijacked by her own body.Emma and Dr. Canestraro discuss the tools that supported her healing, including adequate nutrition, frequent meals, electrolytes, binders, gentle movement, lymphatic support, nervous system regulation, and mindset shifts rooted in safety and trust. Emma also shares what did not help, including extreme diets, fasting, and electrical vagal nerve stimulation, which worsened her symptoms.This episode offers insight, validation, and hope for anyone navigating dysautonomia, chronic illness, or nervous system overload, and emphasizes that healing often begins by slowing down, nourishing the body, and learning to listen to its signals.Let us know your thoughts on this episode hereFor any further information, feel free to email us at info@vagusclinic.com. Our team is happy to help. We offer 20-minute complimentary health calls, and you can sign up for one here.
Osteosarcoma Webinar Series: Joseph Skeate, PhD, an Assistant Professor at the University of Minnesota, discusses his OutSmarting Osteosarcoma funded work (Because of Annaleigh) on next generation dual-CAR gamma delta T cells for the treatment of pediatric osteosarcoma.In this presentation, Dr. Skeate will provide an overview of the next-generation genome engineering strategies deployed for this project and share updates on the development of a gamma-delta chimeric antigen receptor (CAR) T cell therapy for treating osteosarcoma. He will describe how the team is combining non-viral transposon insertion of a CAR transgene with targeted gene modification using an Adenine Base Editor to enhance T cell function in the presence of suppressive factors characteristic of osteosarcoma tumors.Dr Joseph Skeate is an Assistant Professor in the Division of Pediatric Hematology/Oncology at the University of Minnesota. He obtained his PhD in Medical Biology from the University of Southern California Keck School of Medicine. Following his doctoral work, he completed a postdoctoral fellowship at the University of Minnesota under the mentorship of Drs Branden Moriarity and Beau Webber. During this time, he developed a hyperactive transposon system and deployed novel genome engineering approaches using Cas9 systems, creating a powerful toolkit for rapid non-viral engineering and preclinical testing of primary human cells. Leveraging his background and expertise in immunology and genome engineering, his lab now focuses on developing next-generation cellular therapies for rare pediatric disease, including osteosarcoma.
Merve Yoldaş Çelik reviews pediatric cell trafficking disorders, a genetically diverse group that can mimic mitochondrial, lysosomal, and glycosylation disease. Using a 14-patient case series (including two novel variants), she highlights shared multisystem patterns and practical gene-specific clues to support a mechanism-based diagnostic approach. A Multisystem Perspective of Pediatric Cell Trafficking Disorders: Within the Cells, Beneath the Signs Merve Yoldaş Çelik, et al https://doi.org/10.1002/jmd2.70053
What's the opposite of cancer? If you answered “cure,” “antidote,” or “antivenom” — you've obviously been reading the antonym section at www.merriam-webster.com/thesaurus/cancer.But today's guest Athena Aktipis says that the opposite of cancer is us: it's having a functional multicellular body that's cooperating effectively in order to make that multicellular body function.If, like us, you found her answer far more satisfying than the dictionary, maybe you could consider closing your dozens of merriam-webster.com tabs, and start listening to this podcast instead.Rebroadcast: this episode was originally released in January 2023.Links to learn more, video, and full transcript: https://80k.link/AA As Athena explains in her book The Cheating Cell, what we see with cancer is a breakdown in each of the foundations of cooperation that allowed multicellularity to arise: Cells will proliferate when they shouldn't. Cells won't die when they should. Cells won't engage in the kind of division of labour that they should. Cells won't do the jobs that they're supposed to do. Cells will monopolise resources. And cells will trash the environment.When we think about animals in the wild, or even bacteria living inside our cells, we understand that they're facing evolutionary pressures to figure out how they can replicate more; how they can get more resources; and how they can avoid predators — like lions, or antibiotics.We don't normally think of individual cells as acting as if they have their own interests like this. But cancer cells are actually facing similar kinds of evolutionary pressures within our bodies, with one major difference: they replicate much, much faster.Incredibly, the opportunity for evolution by natural selection to operate just over the course of cancer progression is easily faster than all of the evolutionary time that we have had as humans since Homo sapiens came about.Here's a quote from Athena:“So you have to shift your thinking to be like: the body is a world with all these different ecosystems in it, and the cells are existing on a time scale where, if we're going to map it onto anything like what we experience, a day is at least 10 years for them, right? So it's a very, very different way of thinking.”You can find compelling examples of cooperation and conflict all over the universe, so Rob and Athena don't stop with cancer. They also discuss:Cheating within cells themselvesCooperation in human societies as they exist today — and perhaps in the future, between civilisations spread across different planets or starsWhether it's too out-there to think of humans as engaging in cancerous behaviourWhy elephants get deadly cancers less often than humans, despite having way more cellsWhen a cell should commit suicideThe strategy of deliberately not treating cancer aggressivelySuperhuman cooperationAnd at the end of the episode, they cover Athena's new book Everything is Fine! How to Thrive in the Apocalypse, including:Staying happy while thinking about the apocalypsePractical steps to prepare for the apocalypseAnd whether a zombie apocalypse is already happening among Tasmanian devilsChapters:Rob's intro (00:00:00)The interview begins (00:02:22)Cooperation (00:06:12)Cancer (00:09:52)How multicellular life survives (00:20:10)Why our anti-contagious-cancer mechanisms are so successful (00:32:34)Why elephants get deadly cancers less often than humans (00:48:50)Life extension (01:02:00)Honour among cancer thieves (01:06:21)When a cell should commit suicide (01:14:00)When the human body deliberately produces tumours (01:19:58)Surprising approaches for managing cancer (01:25:47)Analogies to human cooperation (01:39:32)Applying the "not treating cancer aggressively" strategy to real life (01:55:29)Humanity on Earth, and Earth in the universe (02:01:53)Superhuman cooperation (02:08:51)Cheating within cells (02:15:17)Father's genes vs. mother's genes (02:26:18)Everything is Fine: How to Thrive in the Apocalypse (02:40:13)Do we really live in an era of unusual risk? (02:54:53)Staying happy while thinking about the apocalypse (02:58:50)Overrated worries about the apocalypse (03:13:11)The zombie apocalypse (03:22:35)Producer: Keiran HarrisAudio mastering: Milo McGuireTranscriptions: Katy Moore
What if we could precisely measure a cell at its most fundamental level? In this episode, we talk with the University of Chicago scientist Peter Maurer about how he and his colleagues made the breakthrough discovery of turning a protein found in living cells into the first biological quantum bit, also known as a qubit.Maurer explains how quantum systems—once thought to be too fragile for real-world use—are becoming some of the most powerful sensors ever built, and what they could teach us about the brain, the body and more. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this captivating episode host Myrna Young discusses a groundbreaking advancement in cancer treatment with Dr. Jeffrey Gross, founder of ReCelebrate. The episode dives deep into the innovative use of Natural Killer (NK) cells as a promising non-toxic alternative to chemotherapy and radiation. Dr. Gross, a renowned expert in regenerative medicine and immunotherapy, explains how NK cell-derived exosomes are reshaping cancer treatment by selectively targeting cancer cells without harming healthy tissue. This conversation promises to shed light on emerging cancer therapies that evoke hope and potential for more humane cancer treatments.With a strong focus on NK cell-derived exosomes, Dr. Gross elaborates on how these natural remedies can boost the immune system, effectively contributing to cancer prevention and management. The episode further explores how current advancements in regenerative medicine are becoming accessible and offer substantial benefits to patients undergoing or at risk of cancer, while possibly enriching the lives of those with genetic predispositions to cancer. This episode provides vital insights into the future of cancer treatment, marking a pivotal moment for patients seeking comprehensive care options that could potentially enhance longevity and overall well-being.Key Takeaways:Revolutionary Cancer Treatment: NK cell-derived exosomes represent a new frontier in cancer treatment, offering a targeted and non-toxic alternative to chemotherapy and radiation therapy.Selective Targeting: These NK exosomes can naturally identify and attack cancer cells while bypassing healthy cells, minimizing collateral damage.Broad Application: Suitable for a variety of cancers, including blood cancers like leukemia and lymphoma, offering diverse treatment possibilities.Preventative Potential: Beyond treatment, NK exosome therapy might reduce cancer recurrence risk and serve as a preventative measure for high-risk patients.Evolving Alternative Medicine: Reflective of the broader trends in regenerative medicine, Dr. Gross and ReCelebrate are at the forefront of offering innovative therapies that prioritize patient well-being with fewer side effects.Notable Quotes:To advertise on our podcast, visit https://advertising.libsyn.com/TransformyourMindor email kriti@youngandprofiting.com See this video on The Transform Your Mind YouTube Channel https://www.youtube.com/@MyhelpsUs/videosTo see a transcripts of this audio as well as links to all the advertisers on the show page https://myhelps.us/Follow Transform Your Mind on Instagram https://www.instagram.com/myrnamyoung/Follow Transform Your mind on Facebookhttps://www.facebook.com/profile.php?id=100063738390977Please leave a rating and review on iTunes https://podcasts.apple.com/us/podcast/transform-your-mind/id1144973094 https://podcast.feedspot.com/personal_development_podcasts/
Send us a textCellular metabolism, mitochondrial health, and the roles of diet and environment in metabolic health, fetal & child development, and Alzheimer's.TOPICS DISCUSSED:Cellular growth vs. burning: Cells alternate between growing (using glucose for building blocks in low-oxygen environments) and burning (generating ATP in mitochondria with oxygen); dysregulation leads to metabolic issues.Key regulatory enzymes: PI3 kinase imports glucose, AMP kinase builds mitochondria, and mTOR drives cell division; their synchronization determines healthy modes, while desynchronization causes diseases.Fructose as a dose-dependent mitochondrial toxin: High fructose intake inhibits AMP kinase, reducing mitochondrial function and diverting energy to fat storage; it is dose-dependent, like alcohol, and unnecessary in the diet.Obesogens & endocrine disruptors: Chemicals like tributyltin (TBT) alter gene expression across generations, promoting obesity unrelated to calories; modern exposures increase reactive oxygen species (ROS), burdening cells.Fetal & neonatal development: Maternal diet, especially high sugar or formula feeding, can cause neonatal obesity and fatty liver; breastfeeding supports proper jaw development and oxygen intake.Brain metabolism & Alzheimer's: The brain's high energy needs make it vulnerable to mitochondrial issues and ROS; energy deficits from diet, stress, and toxins lead to synapse loss and inflammation, treatable via prevention.ROS & health: Mitochondria produce ROS as a byproduct of ATP generation; excess from diet or environment causes damage, but antioxidants and lifestyle can mitigate risks.PRACTICAL TAKEAWAYS:Limit added sugars in your diet to reduce mitochondrial stress and ROS, focusing on whole foods over ultra-processed items for better metabolic health.Prioritize breastfeeding for infants when possible to support proper physical development and reduce future metabolic risks.Incorporate regular exercise and social activities to manage stress and boost brain-protective factors like BDNF, aiding neurodegeneration prevention.Get adequate sleep to regulate cortisol and maintain cellular energy balance, helping prevent brain fog and chronic diseases.ABOUT THE GUEST: Robert Lustig, MD is a pediatric endocrinologist and Professor Emeritus at the University of California, San Francisco, with a background in neuroendocrinology and obesity research.*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts
Today on the Grave Talks, we step behind the iron bars of one of California's most haunted jails with Amy Davis of Gothic Paranormal. Based in Jackson, California—a Gold Rush town rich in ghostly history—Amy has spent countless nights investigating the Old Amador County Courthouse and Jail. She has spent years exploring this historic site, uncovering its layered history and paranormal secrets. Beneath its polished Art Deco exterior lies the original 1860s brick structure—a remnant of Jackson's wild frontier days, when justice was swift and not everyone who entered those jail cells ever truly left. From phantom footsteps and unexplained whispers to one particularly active spirit known as Sammy, the courthouse remains a hub of supernatural energy. Today on The Grave Talks, we explore Jackson's haunted past and the ghosts that refuse to fade away. For more information on ghost tours and investigations, visit restoreamador.com. For more information on Amy, follow Gothic Paranormal on Facebook or Instagram. #TrueGhostStory #HauntedCalifornia #OldAmadorJail #GothicParanormal #GhostHunters #HauntedHistory #ParanormalPodcast #JacksonCA #RealHauntings #GoldRushGhosts Love real ghost stories? Don't just listen—join us on YouTube and be part of the largest community of real paranormal encounters anywhere. Subscribe now and never miss a chilling new story:
Today on the Grave Talks, we step behind the iron bars of one of California's most haunted jails with Amy Davis of Gothic Paranormal. Based in Jackson, California—a Gold Rush town rich in ghostly history—Amy has spent countless nights investigating the Old Amador County Courthouse and Jail. She has spent years exploring this historic site, uncovering its layered history and paranormal secrets. Beneath its polished Art Deco exterior lies the original 1860s brick structure—a remnant of Jackson's wild frontier days, when justice was swift and not everyone who entered those jail cells ever truly left. From phantom footsteps and unexplained whispers to one particularly active spirit known as Sammy, the courthouse remains a hub of supernatural energy. Today on The Grave Talks, we explore Jackson's haunted past and the ghosts that refuse to fade away. This is Part Two of our conversation. For more information on ghost tours and investigations, visit restoreamador.com. For more information on Amy, follow Gothic Paranormal on Facebook or Instagram. #TrueGhostStory #HauntedCalifornia #OldAmadorJail #GothicParanormal #GhostHunters #HauntedHistory #ParanormalPodcast #JacksonCA #RealHauntings #GoldRushGhosts Love real ghost stories? Don't just listen—join us on YouTube and be part of the largest community of real paranormal encounters anywhere. Subscribe now and never miss a chilling new story:
In the last year, you've basically replaced your body weight in new cells. So yes, it's a new year, new you. To ring in 2026, we're talking about starting anew, and drawing inspiration from tiny worms that embody the ultimate growth mindset—they can regrow a whole body from just a tiny piece of their tail. In this festive episode, Host Flora Lichtman talks with biologist Alejandro Sánchez Alvarado, a pioneer in the field of regeneration, about the science of regeneration and the biology lessons we can carry into the new year. Guest: Dr. Alejandro Sánchez Alvarado is a biologist and president and chief scientific officer of the Stowers Institute for Medical Research in Kansas City, Missouri.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
Podcast Description: The Cellular Breakthrough That Changed How I See Chronic IllnessSchedule a Discovery Zoom call to see if we can help you!Welcome to today's episode with Doctor Hugh. In this podcast, I share a simple but powerful idea that has helped many of my clients heal faster than ever before.This is about cell energy, sunlight, and how your body makes power to heal.What This Episode Is AboutA cellular breakthrough that changed how I treat chronic illnessWhy many sick people are still not getting betterHow the body uses light like plants use sunlightWhy energy comes before detoxOne affordable tool that helps fragile and very sick people healWho This Episode Is ForIf you struggle with:FibromyalgiaBrain fogIBS or gut problemsDamage from antibioticsChronic fatigueTrouble thinking or memory lossThis episode is for you.The Big Idea: Your Body Uses LightPlants use sunlight to grow foodThis process is called photosynthesisYour body works in a similar waySpecial light waves help your cells make energyWhen you don't get enough of these light waves:Cells slow downMitochondria stop working wellHealing becomes very hardWhy Chronic Illness HappensMany sick people are low in healthy light exposureModern life keeps us indoorsYour cells become energy starvedLow energy leads to pain, inflammation, and diseaseWhy Infrared Light MattersMost sunlight energy is invisibleOnly a small part is visible lightInfrared light makes up over half of the sun's energyThis light goes deep into the bodyDeep light helps:Mitochondria make energyCells repair themselvesThe body heal without stressNot All Heat Is the SameThis is not about sweatingSick people should not push detoxThe goal is gentle energy supportThe wavelength does the workWhy I Recommend an Infrared Sauna BlanketSkin-to-skin contact gives deep penetrationWorks without extreme heatSafe for very fragile peopleAffordable and easy to use at homeKey benefits:Supports energy productionHelps cells heal naturallyNo harsh detox reactionsUnderstanding Infrared Light (Simple Version)Near infrared = closer to visible lightMid infrared = middle rangeFar infrared = deepest penetrationFar infrared goes deepest, reaching:CellsMitochondriaCell membranesThat's why it matters most for chronic illness.Why Deeper Is BetterDeeper light reaches energy factories in cellsEnergy leads to repairRepair leads to healingJust like sunlight feeds plants:Infrared light feeds your cellsReal ResultsSince focusing on energy first:Clients heal fasterProgress is smootherLess crashing and setbacksBetter long-term recoveryFinal MessageYou do not need to suffer.You need:The right energyThe right guidanceA plan made for your bodyNext StepsVisit my websiteSchedule a callGet a guided plan made just for youHealing
Have you ever said, "I just don't feel like myself anymore" — even though your labs look normal? In this episode of the Health Fix Podcast, Dr. Jannine Krause breaks down why inflammation starts in the brain, how it drives fatigue, brain fog, cravings, hormone imbalance, and accelerated aging — and why 2026 is the year to stop suppressing symptoms and start correcting root causes. Inflammation isn't just a body problem. It's a brain health issue first. Your brain uses 20% of your daily calories, and when inflammation is present, it shifts into defensive mode, not performance mode. That's when clarity disappears, energy crashes, and nothing feels like it's working anymore.
Happy Holidays- New Episodes starting Jan. 5th Every cell in your body changes, so why do you have a sense of continuity of the self – as though you're the same person you were a month ago? What does this have to do with the watercraft of the Greek demigod Theseus, or the End-of-History illusion, or why you go through so much trouble to make things comfortable for your future self, even though you don't know that person? And if there really were an afterlife, what age would your deity make everyone for living out their eternities? Join this week for a two-parter about the mysteries of selfhood.
Exercise trains your immune system to respond faster and recover more efficiently, helping you stay energized and more resistant to illness Years of consistent moderate training reshape how your immune cells produce and manage energy, keeping them youthful and resilient as you age Active adults maintain steadier inflammation and bounce back quicker from stress, reducing fatigue, soreness, and lingering symptoms after illness Daily walking with short, high-quality strength sessions builds immune stability without overwhelming your system or spiking stress hormones Training your immune cells through repetition — not intensity — gives you lasting protection, better recovery, and steadier energy throughout your life
Support your health journey with our private practice! Explore comprehensive lab testing, functional assessments, and expert guidance for your wellness journey. Find exclusive offers for podcast listeners at nutritionwithjudy.com/podcast. _____Dr. Bill and I talk about how chronic illness is really about cellular dysfunction and why herbal therapies can be a game-changer when elimination diets and medications aren't enough. We also discuss the five root causes of cellular stress and how to support long-term healing without harming the body. Make sure to watch the full interview to learn more.Dr. Bill Rawls is a board-certified physician who turned to herbal and holistic therapies after facing his own health crisis with chronic Lyme disease. Frustrated by the limitations of conventional medicine, he explored cellular wellness as the foundation of healing. His recovery inspired a new mission: to help others restore their health by addressing the root causes of chronic illness.We discuss the following:All about Dr. Bill RawlsDr. Rawls' definition of chronic illnessThe first four levers of illnessCellular health preventing Lyme emergenceDr. Rawls' favorite starter herbalsCommon protocols used by Dr. RawlsRole of biofilm breakers and bindersPrioritizing infections in treatmentInsights on bioidentical hormone usePeptides and their classification as hormonesImportance of sourcing quality herbsHealing story from a patientWhere to access Dr. Rawls programs_____EPISODE RESOURCESWebsiteVital PlanDr. Bill Rawls articlesRESTORE180 programThe Cellular Wellness Solution bookEFH Personalized Health Plan_____WEEKLY NEWSLETTER
The Fathers do not flatter us here. They speak with a severity that at first wounds, then heals, if we allow it. They do not treat resentment as a minor flaw of temperament or a passing emotional reaction. They name it for what it is: a poison that slowly erodes the soul's capacity to remember God. Abba Makarios goes straight to the heart of the matter. To remember wrongs is not simply to remember events. It is to allow those events to take up residence within us, to become a lens through which everything is filtered. The tragedy is not primarily that we remain hurt. It is that the remembrance of God grows faint. The mind cannot hold both rancor and divine remembrance at the same time. One displaces the other. When resentment is cherished, prayer becomes difficult, then hollow, then distorted. The heart turns inward and begins to feed on its own injuries. The Fathers are unsparing here because they know how subtle rancor is. Other sins shock us into repentance. A lie, a fall, a moment of weakness often leaves the soul groaning almost immediately. But rancor settles in quietly. It eats and sleeps with us. It walks beside us like a companion we no longer question. Abba Isaiah and the Elder of the Cells both know this danger. Resentment does not merely coexist with spiritual life; it corrodes it from within, like rust consuming iron. The soul grows hard while imagining itself justified. And yet, alongside this severity, there is a startling tenderness. The Fathers do not say that healing comes through argument, vindication, or emotional catharsis. They prescribe something far more humbling and far more powerful: prayer for the one who has wounded us. Not a feeling of goodwill, not an internal resolution, but the concrete act of standing before God and interceding. Again and again the teaching is the same. Pray for him. Pray for her. Force yourself if you must. Obey even when the heart resists. The story of the brother who obeyed the Elder and prayed is quietly miraculous. Nothing dramatic happens. There is no confrontation, no apology demanded, no psychological analysis. Within a week, the anger is gone. Not suppressed. Extinguished. Grace works where the will yields, even reluctantly. The healing is not self-generated. It is given. The account of the two brothers under persecution reveals just how serious this is. One accepts reconciliation and is strengthened beyond his natural limits. The other clings to ill will and collapses under the same torments. The difference is not courage or endurance. It is love. Grace remains where love remains. When rancor is chosen, protection is withdrawn, not as punishment, but because the soul has closed itself to the very atmosphere in which grace operates. St. Maximos names the interior mechanism with precision. Distress clings to the memory of the one who harmed us. The image of the person becomes fused with pain. Prayer loosens that bond. When we pray, distress is separated from memory. Slowly, the person is no longer experienced as an enemy but as a suffering human being in need of mercy. Compassion does not excuse the wrong. It dissolves its power. What is perhaps most astonishing is the Fathers' confidence that kindness can heal not only the one who was wounded, but the one who wounds. Be kind to the person who harbors resentment against you, St. Maximos says, and you may deliver him from his passion. This is not naïveté. It is spiritual realism. Demons feed on mutual hostility. They lose their dwelling place when humility and gentleness appear. Foxes flee when the ground is no longer hospitable. St. Ephraim's image is unforgettable. Rancor drives knowledge from the heart the way smoke drives away bees. The heart was made to gather sweetness. When bitterness fills the air, nothing can remain. Tears, prayer, and the offering of oneself like incense clear the space again. This teaching is beautiful because it is honest. It does not minimize the pain of insult or harm. It is challenging because it leaves us without excuses. We cannot claim prayer while nursing grudges. We cannot claim suffering for Christ while secretly rejoicing at another's downfall. The path offered is narrow and costly, but it is also liberating. Resentment chains us to the past. Kindness loosens the chain. Prayer opens the hand. Grace does the rest. --- Text from chat during the group: 00:04:55 Fr. Charbel Abernethy: Page 332 Section B Hypothesis XLII Volume II 00:11:28 Fr. Charbel Abernethy: Page 332 Section B Hypothesis XLII Volume II 00:11:41 Janine: Yes, thank you Uncle Father! 00:11:57 Fr. Charbel Abernethy: Reacted to "Yes, thank you Uncle..." with
Timeline Mitopure Gummies — The #1 Urolithin A supplement for energy and healthy aging, now in delicious strawberry gummies. Get 20% off at timeline.com/vanessa What if the real driver of skin aging isn't wrinkles or sun damage — but "zombie" senescent cells hiding in your skin? In this episode of the Optimal Protein Podcast, Vanessa sits down with Dr. Alessandra Zonari, PhD — a stem cell biologist and longevity scientist — for a fascinating deep dive into the new peptide science behind skin aging, inflammation, and biological age. BOOST YOUR COLLAGEN & ELASTIN with RED LIGHT THERAPY! Save 25% on all Tone Lux Red Light therapy with the code HOLIDAY25! Learn more about the TONE LUX Crystal red light therapy mask and the brand new accessory the TONE LUX CONTOUR for the neck and décollete You'll discover: What senescent "zombie" skin cells actually are — and why they don't just age themselves, but affect the surrounding tissue How inflammation in the skin can quietly accelerate collagen breakdown and visible aging Why skin aging speeds up during fat loss, perimenopause, and menopause How scientists are now measuring the biological age of skin, not just how it looks The surprising role of peptides in signaling skin cells to behave more youthfully Why some common "anti-aging" approaches may miss the real drivers of aging What makes lip skin biologically different — and why it tends to age faster than the rest of the face Why nighttime repair, autophagy, and even red light therapy may matter more than you think This conversation goes far beyond skincare routines. It explores the mechanisms of aging at the cellular level, how lifestyle choices influence skin health, and why skin may be one of the most overlooked markers of longevity. If you're interested in skin health, peptides, collagen, inflammation, fat loss, or aging well, this episode will completely change how you think about your skin. Mentioned in this episode: OneSkin is powered by the breakthrough peptide OS-01, the first ingredient proven to reduce skin's biological age. I use the OS-01 Face and Eye formulas daily—they've transformed my skin's smoothness, firmness, and glow. Visit oneskin.co/VANESSA and use code VANESSA for 15% off your first purchase. Vanessa discusses how red light therapy supports mitochondrial health, muscle recovery, circulation, and skin health as part of an evidence-based approach to fat loss and metabolic optimization. Explore the Tone LUX red light therapy collection at
A High Court judge has ordered the Department of Corrections boss to obey the law or face contempt of court proceedings if he fails to make sure prisoners aren't let out of their cells for an hour everyday to exercise. Justice Jason McHerron found some inmates in Auckland Prison weren't allowed the minimum time required under law, and is holding the Corrections chief executive Jeremy Lightfoot personally accountable. Finn Blackwell has more.
In Episode 022 of DEFCON ZERQ, Alpha Warrior and Josh Reid react in real time to President Trump's “My Fellow Americans” announcement and unpack the signals surrounding an imminent national address. The conversation dives into escalating global and domestic tensions, including suspected cartel activity, embassy corruption, terror incidents, and mounting pressure inside the Trump administration. Alpha and Josh analyze the Susie Wiles controversy, withheld intelligence, ambassador shakeups, and the possibility of a major internal realignment, while connecting dots between Q references, timing markers, and recent Truth Social posts. The episode also explores media manipulation, foreign influence, censorship pressure campaigns, and why multiple events appear to be converging at once. Fast paced, speculative, and deeply connective, this episode captures the sense that something significant may be approaching and why the hosts believe the next moves matter.
Susan Schwab talks about how she got the research bug, bugs she ate, and her research on how the lipid S1P helps T cells decide- should I stay or should I go. Host: Cindy Leifer Guest: Susan Schwab Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Schwab lab website Monocytes produce the lipid S1P to regulate T cell movement Review on S1P and immune cell migration Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
From thwarted New Year's Eve terror plots to America's hidden chocolate stashes, this episode covers the stories you can't ignore. We dive into the FBI's arrest of a terror cell linked to Iran and extremist groups, the complexities of illegal immigration and national security, and the staggering $10B lawsuit against the BBC for allegedly doctored January 6th footage.
Tara breaks down new details surrounding an FBI-arrested terror cell allegedly tied to Antifa ideology, Iranian influence, and plans for coordinated New Year's Eve attacks. From desert weapons testing to drone surveillance, from threats against ICE agents to the growing merger between radical leftist movements and jihadist symbolism, this episode connects dots many refuse to see. ⚠️ This isn't fringe speculation.
Send us a textLost cells on Apple, Spotify and any where you listen to your podcasts. SWI swissinfo.ch is a public service media company based in Bern, Switzerland.
Get the stories from today's show in THE STACK: https://justinbarclay.comJoin Justin in the MAHA revolution - http://HealthWithJustin.comProTech Heating and Cooling - http://ProTechGR.com New gear is here! Check out the latest in the Justin Store: https://justinbarclay.com/storeKirk Elliott PHD - FREE consultation on wealth conservation - http://GoldWithJustin.comTry Cue Streaming for just $2 / day and help support the good guys https://justinbarclay.com/cueUp to 80% OFF! Use promo code JUSTIN http://MyPillow.com/JustinPatriots are making the Switch! What if we could start voting with our dollars too? http://SwitchWithJustin.com
Join me for a fascinating deep dive into the science of immune aging with Dr. Natalia Mitin, founder and CEO of Sapere Bio. We explore why the aging of the immune system is the primary driver of aging for the entire body and unpack the concept of cellular senescence—often called "zombie cells"—where stressed cells persist and create chronic inflammation. Dr. Mitin explains why consumer tests that assign a specific "biological age" in years are often scientifically lacking compared to measuring where you stand within a population's trajectory. We also discuss cutting-edge longevity targets, including T-cell exhaustion (and how drugs like Rapamycin and SGLT2 inhibitors address it), the critical role of gut health (where 70% of the immune system resides), and how mitochondrial function in stem cells can correlate with an extra 15 years of healthspan.
We love to hear from our listeners. Send us a message. On this week's episode of the Business of Biotech, Sean Ainsworth, CEO and Chairman at Immusoft, talks about transitioning from the research bench to entrepreneurship, his M&A experiences as a biotech founder, and why engineered B cell therapies offer a better, more patient-friendly administration for lysosomal storage diseases currently treated with enzyme replacement therapies. Sean also discusses FDA pathways, incentives, and agency engagement, and offers thoughts on the regulatory outlook for cell and gene therapies. Access this and hundreds of episodes of the Business of Biotech videocast under the Business of Biotech tab at lifescienceleader.com. Subscribe to our monthly Business of Biotech newsletter. Get in touch with guest and topic suggestions: ben.comer@lifescienceleader.comFind Ben Comer on LinkedIn: https://www.linkedin.com/in/bencomer/
Dr. Petri Bono, Chief Medical Officer at Faron Pharmaceuticals, describes the development of bexmarilimad, a novel first-in-class immunotherapy that, unlike existing checkpoint inhibitors targeting T cells, targets the Clever 1 receptor on macrophages. This treatment is designed to reprogram the tumor microenvironment by switching marcophages from suppressive to active, enabling the patient's immune system to recognize and attack cancer cells. The primary disease target is higher-risk Myelodysplastic syndromes because the cancer cells in virtually all MDS patients express the Clever 1 target. Petri explains, "We are developing a completely new type of treatment. Currently, cancer patients are treated with immunotherapies called checkpoint inhibitors that target immune checkpoints. But our approach is targeting completely different cells, not T cells, but rather macrophages. And that's why we are first in class with a novel mode of action. And that's why it's important that these macrophages are shown to, for example, contribute to treatment resistance in many tumors." "Clever 1 actually is a receptor that was identified about 20 years ago. It found a certain macrophage as well as myeloid cells. And Clever 1 keeps the immune system in a tolerant and suppressive state. In cancer, for example, these Clever 1-positive macrophages essentially help the malignancy grow instead of helping to fight against it. And then our approach is that we want to block Clever 1 with our monoclonal antibody, bexmarilimab. So those macrophages switch the phenotype into an active antigen, preventing a pro-inflammatory state, and this reawakens immune surveillance. It allows T cells in the system to actually recognize the malignant cells themselves as dangerous and mount a proper antitumor response. So, a completely new mode of action by targeting Clever 1, we are not just adding another cytotoxic mechanism. We are removing the immune break and enabling the patient's own immune system to do the job that it was originally designed to do." #FaronPharmaceuticals #BloodCancer #MDS #MyelodysplasticSyndrome #HR-MDS #CancerResearch #novelimmunotherapy #Bexmarilimab #Clever1 faron.com Listen to the podcast here
Dr. Petri Bono, Chief Medical Officer at Faron Pharmaceuticals, describes the development of bexmarilimad, a novel first-in-class immunotherapy that, unlike existing checkpoint inhibitors targeting T cells, targets the Clever 1 receptor on macrophages. This treatment is designed to reprogram the tumor microenvironment by switching marcophages from suppressive to active, enabling the patient's immune system to recognize and attack cancer cells. The primary disease target is higher-risk Myelodysplastic syndromes because the cancer cells in virtually all MDS patients express the Clever 1 target. Petri explains, "We are developing a completely new type of treatment. Currently, cancer patients are treated with immunotherapies called checkpoint inhibitors that target immune checkpoints. But our approach is targeting completely different cells, not T cells, but rather macrophages. And that's why we are first in class with a novel mode of action. And that's why it's important that these macrophages are shown to, for example, contribute to treatment resistance in many tumors." "Clever 1 actually is a receptor that was identified about 20 years ago. It found a certain macrophage as well as myeloid cells. And Clever 1 keeps the immune system in a tolerant and suppressive state. In cancer, for example, these Clever 1-positive macrophages essentially help the malignancy grow instead of helping to fight against it. And then our approach is that we want to block Clever 1 with our monoclonal antibody, bexmarilimab. So those macrophages switch the phenotype into an active antigen, preventing a pro-inflammatory state, and this reawakens immune surveillance. It allows T cells in the system to actually recognize the malignant cells themselves as dangerous and mount a proper antitumor response. So, a completely new mode of action by targeting Clever 1, we are not just adding another cytotoxic mechanism. We are removing the immune break and enabling the patient's own immune system to do the job that it was originally designed to do." #FaronPharmaceuticals #BloodCancer #MDS #MyelodysplasticSyndrome #HR-MDS #CancerResearch #novelimmunotherapy #Bexmarilimab #Clever1 faron.com Download the transcript here
Donate (no account necessary) | Subscribe (account required) Join Bryan Dean Wright, former CIA Operations Officer, as he dives into today's top stories shaping America and the world. In this episode of The Wright Report, Bryan covers the Pentagon's new Inspector General findings on Secretary of War Pete Hegseth's use of the Signal app, Eric Swalwell's push for voting by phone, new revelations about how the Afghan terrorist in Washington was radicalized, a Senate bill that would end dual citizenship, and promising research on depression and mental health. Pentagon IG Clears Hegseth of Wrongdoing: The Inspector General found that senior Trump officials violated protocol by discussing Yemen strike operations on the Signal app, but that Hegseth had legal authority to declassify what he shared. The report warns that using personal devices creates risk, although no adversary appears to have intercepted the information. Bryan describes the episode as sloppy tradecraft that prompted the administration to tighten internal communications procedures. Swalwell Pushes Voting by Phone: California Democrat Eric Swalwell is proposing phone-based voting, insisting it can be secure. Bryan counters with his CIA experience, explaining that any phone-based voting system would be a prime target for foreign intelligence services. He argues that electronic voting in any form creates undetectable vulnerabilities that nations like China and Russia would exploit. How the Afghan Terrorist Was Radicalized: New reporting shows that Rahmanullah Lakanwal told his wife he was meeting with members of the Tablighi Jamaat, a Deobandi revivalist movement with a long history of extremism. The group has terror cells in parts of the United States, and Lakanwal previously assisted the CIA in killing their members overseas. Bryan explains why investigators are now trying to determine whether cells in Phoenix, San Diego, Chicago, Indianapolis, or on the East Coast are connected to the attack. Senator Proposes Ending Dual Citizenship: Ohio Senator Bernie Moreno introduced a bill requiring Americans to hold only United States citizenship. He argues that dual allegiance creates legal and security conflicts and says becoming an American should be an all-or-nothing commitment. Bryan encourages listeners who support the idea to contact their senators and weigh in. Mental Health Research Offers Hope: Studies show that taking a weeklong break from social media reduces depression and insomnia. British researchers also found that nitrous oxide treatments can rapidly improve severe depression when other therapies fail, and exercise and time in nature remain highly effective for anxiety and mood disorders. "And you shall know the truth, and the truth shall make you free." - John 8:32 Keywords: Pentagon IG report, Signal app, Pete Hegseth declassification authority, Eric Swalwell voting by phone, NSA hacking risks electronic voting, Rahmanullah Lakanwal Tablighi Jamaat radicalization, dual citizenship, Exclusive Citizenship Act, depression research nitrous oxide, social media break mental health
Carolina Reis Oliveira, PhD and co-founder of OneSkin (code: BIOHACKINGBRITTANY), exposes why so many "anti-aging" products quietly inflame your skin, accelerate cellular aging, and wreck your barrier — and what a true longevity-first skincare routine looks like instead. We unpack senescent "zombie cells", exosome facials, NAD+ creams, rating apps like EWG and Yuka, and how to choose products that are both clean and clinically effective without overloading your skin. As a mom and longevity nerd, I also ask her how women can simplify their routines without sacrificing results, especially when we're juggling babies, work, and sleep. Join my 12 Holiday Rituals Giveaway for a chance to win part of $5,500+ USD in wellness prizes. Open until December 24th! WE TALK ABOUT: 02:00 - Why OneSkin started by testing popular "anti-aging" creams on real human skin 10:35 - What senescent "zombie cells" are and why they act like rotten apples inside your skin 14:15 - Why OneSkin keeps its OS-01 peptide topical (not oral) and what that means for safety vs. supplements 17:45 - Exosome facials, plant stem cell exosomes, and how to tell if what's in the vial is actually still active 19:15 - NAD, NMN, niacinamide and so-called "mitochondria" creams — what the data really shows on skin aging 25:55 - The kinds of clinical tests and lab data Carolina looks for before she'll trust a formula 31:05 - Exactly where OneSkin fits into your routine with vitamin C, retinol, eye creams and exfoliants 34:05 - Non-comedogenic formulas, coconut oil breakouts and how OneSkin formulates for acne-prone skin 39:15 - How to actually use a gua sha for lymph drainage, jaw tension and lip lines 40:35 - The future of longevity: Shifting from "anti-aging" to extending women's healthspan and vitality into our 70s and 80s 43:40 - Hormone therapy, prevention and why "just get used to it, you're getting old" is a dangerous narrative 45:40 - How to spot longevity greenwashing in both skincare and supplements RESOURCES: Free gift: Download my hormone-balancing, fertility-boosting chocolate recipe. Explore my luxury retreats and wellness events for women. Shop my faves: Check out my Amazon storefront for wellness essentials. OneSkin's website (code: BIOHACKINGBRITTANY) and Instagram Join my 12 Holiday Rituals Giveaway before December 24th LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music
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CraftLit - Serialized Classic Literature for Busy Book Lovers
Ep. 703: Mr. Harrison's Confessions | Chapters 25-231 Book talk begins at 19:44 Elopements, mistaken romances, and surprise weddings? Yes. ALL of that. --------------------------------------------------------------- 0:00 - Start 01:48 - Don't forget to send us your crafty videos 03:08 - BOOKMARKS sign up closed - if you made a bookmark and didn't sign up, email Heather@craftlit.com 03:40 - Game of Wool a review on Nimble Needles, interview (pre-show) with a real Fair Isle knitter, and Gordon's explanation of: (a) What happened on the show (b) steeking. 07:23 - GOOD EATS IS BACK?! Alton Brown Cooks Food 08:50 - Saw Nuremberg— I found Charles Burns'—the editor's—papers Of Doug Kelly's book "22 Cells in Nuremberg," but I believe they're jpgs of every page—please share if you find a better copy https://collections.ushmm.org/search/catalog/irn501848?rsc=112566&cv=1&x=1352&y=1746&z=3.3e-4),also saw Death by Lightning—very funny until it's not. Trailer: Death by Lightning | Official Trailer | Netflix - and How Accurate was Netflix's "Death by Lightning?" – Episode 1: Garfield's Nomination —the one character I thought was a composite in Nuremberg was not: Howard Triest Howard Triest Documentary (https://en.wikipedia.org/wiki/Howard_Triest#cite_note-6). He was portrayed by Leo Woodall in the 2025 film Nuremberg. 14:07 - Frankenstein—Non-gory scenes by request: Elizabeth non-gory scene with meeting Creature https://youtu.be/1rO8QDtsvNA?si=m2Ls0B9GXLmHDGJr (Actress Mia Goth, Harriet from Anya Taylor Joy's Emma) Short of Elizabeth's costumes https://youtube.com/shorts/2S9SqvN_5aA?si=Q-meab1xvqiG2CgM, Someone edited together her entire character arc from when the creature is awakened to her end—100% no gore: https://youtu.be/OUezG3wmwHE?si=HtbMGoXXaF3zTrmn, Jacob Elordi's transformation in the makeup chair: https://youtube.com/shorts/UbrtReRi408?si=qYlbDdsVZtRNpJ1T+ for this short—which is nearly the whole film—close your eyes for a long blink when you see the shower of sparks fly in the laboratory. You'll skip the only semi-gruesome 1 second cut: https://youtube.com/shorts/aUfoXryGQR0?si=gO96SXPs1tYbu8Tp 17:03 - BUYER BEWARE link on Substack 17:31 - New Listening options COMING SECOND WEEK OF DECEMBER—better-than-Patreon: Supercast If you're having issues with CraftLit.com's Premium pages, please let us know! Heather@Craftlit.com (put TECH SUPPORT in the subject line) BOOK TALK 19:44 - Book talk 19:53 - WE NEED A MY LADY LUDLOW READER! 24:19 - Jenny Lind - HUGELY famous Swedish opera singer, often called the "Swedish Nightingale 25:10 - Prolix—too many words 27:40 - Fermented brined pickles have probiotics—share any recipes you like! 29:39 - CHAPTER AUDIO chapters 25–31 Miscellaneous 1:00:46 - December 18th—Last Book Party of 2025, 8 pm Eastern: Dec Book Party — Lamb: The Gospel According to Biff, Christ's Childhood Pal (book) 01:02:34 - Making the Profane, Profound - interview with Christopher Moore, author of Lamb: https://youtu.be/1ZBuWQqIgEk?si=aI0aZqt96WP1bFa_ 1:04:10 - Free movie on December 4th—It's a Wonderful Life, on Discord in the Free movie channel, 8 pm Eastern *CraftLit's Socials* • Find everything here: https://www.linktr.ee/craftlitchannel • Join the newsletter: http://eepurl.com/2raf9 • Podcast site: http://craftlit.com • Facebook: https://www.facebook.com/CraftLit/ • Facebook group: https://www.facebook.com/groups/craftlit • Pinterest: https://www.pinterest.com/craftlit/ • TikTok podcast: https://www.tiktok.com/@craftlit • Email: heather@craftlit.com • Previous CraftLit Classics can be found here: https://bit.ly/craftlit-library-2023 *SUPPORT THE SHOW!* • CraftLit App Premium feed bit.ly/libsynpremiumcraftlit (only one tier available) • PATREON: https://patreon.com/craftlit (all tiers, below) ——Walter Harright - $5/mo for the same audio as on App ——Jane Eyre - $10/mo for even-month Book Parties ——Mina Harker - $15/mo for odd-month Watch Parties *All tiers and benefits are also available as* —*YouTube Channel Memberships* —*Ko-Fi* https://ko-fi.com/craftlit —*NEW* at CraftLit.com — Premium Memberships https://craftlit.com/membership-levels/ *IF you want to join a particular Book or Watch Patry but you don't want to join any of the above membership options*, please use PayPal.me/craftlit or CraftLit @ Venmo and include what you want to attend in the message field. Please give us at least 24 hours to get your message and add you to the attendee list. • Download the FREE CraftLit App for iOS or Android (you can call or email feedback straight from within the app) • Call 1-206-350-1642
BASED ON A TRUE STORY (BOATS EP. 378) — Discover the historical accuracy behind the 2025 film "Nuremberg" which is adapted from Jack El-Hai's book "The Nazi and the Psychiatrist."Get Jack's Book: The Nazi and the PsychiatristLearn about the real Dr. Douglas Kelley (Rami Malek) and his complex relationship with Hermann Göring (Russell Crowe) during the historic Nuremberg trials. What did the filmmakers get right and what did they change from the true story? Tune in to find out!Also MentionedJack El-Hai Official WebsiteNuremberg (2025 Film)22 Cells in Nuremberg by Douglas KelleyHowie Trieste's Book on Nuremberg ExperiencesStars and Stripes Military NewspaperChapters0:00 Intro2:35 Movie Overview - Nuremberg and Main Characters5:45 Historical Grade and Book Comparison9:10 Goering's Capture by Allied Forces14:20 Douglas Kelley's Role as Psychiatrist18:55 Goering and Rudolf Hess Relationship23:45 Goering's Narcissism and Motivations29:00 Concentration Camp Films and Kelley's Turning Point33:15 Reporter Character and Kelley's Departure37:00 Howie Trieste's Story as German-Jewish Translator41:45 Kelley Handing Over Research to Prosecutors45:15 Goering's Cyanide Pill and Suicide48:00 Final Lessons and Democracy Warnings50:30 Behind-the-Scenes Film Production Story52:15 Two Truths and a Lie Answer RevealSupport My WorkSupport my sponsorsBecome a BOATS Producer (name in credits + ad-free episodes)Join the BOATS DiscordGet the BOATS email newsletterEmail me: dan@basedonatruestorypodcast.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Immune discusses cross-reactive antibodies to avian influenza neuraminidases and a role for gut-derived T cells in the brain to regulate eating behavior. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Antibody cross-reactivity to influenza H5N1 (Cell Host Microbe, 2025) Gut-derived T cells regulate behavior (Nature, 2025) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.
Support the Institute today. https://givenow.nova.edu/the-institute-for-neuro-immune-medicine-inim-2025 Haylie Pomroy sits down with Dr. Theoharis Theoharides to dive into the complex world of mast cells, environmental toxins, and mold exposure. Dr. Theoharides shares insights from over 40 years of research, explaining how our immune system, particularly mast cells, responds to allergens, parasites, mold, and environmental stressors. From the hidden dangers in our homes to the toxins in everyday food, he highlights how chronic exposure can trigger inflammation, chronic fatigue, neurological symptoms, and autoimmune responses. Sign up for the COVID-UPP Study: https://redcap.nova.edu/redcap/surveys/?s=RMEDJ7LKCX&_gl=1*1h830h7*_gcl_au*MTM2NDA0MTQyOS4xNzE1MDA0ODAy If you are interested in joining a Gulf War Illness (GWI) trial, please complete the Recruitment Registry Form. https://redcap.nova.edu/redcap/surveys/?s=Y9YF8JJWJRK8HEKL%20&_gl=1*1fipp18*_gcl_aw*R0NMLjE3MDc5MTgwMzIuRUFJYUlRb2JDaE1JeWNyUXVfcXFoQU1WU1pCYUJSM3AyQWRBRUFBWUFTQUFFZ0s1NWZEX0J3RQ..*_gcl_au*MTg2NjgwMDQ4Ni4xNzA3MTQwNzgx Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet. Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com Instagram: https://www.instagram.com/hayliepomroy Facebook: https://www.facebook.com/hayliepomroy YouTube: https://www.youtube.com/@hayliepomroy/videos LinkedIn: https://www.linkedin.com/in/hayliepomroy/ X: https://x.com/hayliepomroy Enjoy our show? Please leave us a 5-star review on the following platforms so we can bring hope and help to others Apple Podcasts: https://podcasts.apple.com/us/podcast/hope-and-help-for-fatigue-chronic-illness/id1724900423 Spotify: https://open.spotify.com/show/154isuc02GnkPEPlWfdXMT Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d This podcast is brought to you by the Institute for Neuro-Immune Medicine. Learn more about us here. Website: https://www.nova.edu/nim/ Facebook: https://www.facebook.com/InstituteForNeuroImmuneMedicine Instagram: https://www.instagram.com/NSU_INIM/ Twitter: https://www.twitter.com/NSU_INIM
Lee Cronin is Regius Chair of Chemistry at the University of Glasgow. Among his many pursuits are the digitization of chemistry, the discovery of alien life, and the creation of artificial life. In this episode, Robinson and Lee focus on astrobiology, the chemistry of life as we know it, and the controversies surrounding artificial intelligence.Lee's Website: https://www.chem.gla.ac.uk/cronin/Lee's Twitter: https://x.com/leecroninOUTLINE00:00 Introduction00:55 Lee's Interests in the Origin of Life10:29 Is Life Unique to Earth?18:16 What Is the Self?24:05 Is the Selfish Gene Hypothesis Wrong?30:46 How Does Sand Turn into Cells?44:02 What Is Chemputation?45:41 What Is Assembly Theory?01:11:33 Why Won't We Find a Mine of Coffee Mugs on an Asteroid?01:25:09 Has AI Become a Cult?01:32:16 Will AI Use Biological Weapons to Wipe Out Humanity?01:55:24 Why AI Can't Be AgentsRobinson's Website: http://robinsonerhardt.comRobinson Erhardt researches symbolic logic and the foundations of mathematics at Stanford University, where he is also a JD candidate in the Law School.
James Patterson joins the show to talk about Disrupt Everything—and Win: Take Control of Your Future, his new playbook for turning constant disruption into something useful rather than paralyzing. He explains how he thinks about "positive" versus "negative" disruptors, wrestles with whether the gospel of disruption feeds our narcissism, and defends his literacy work and banned YA novels in places like Florida. Mike then presents to him evidence that one of the book's inspirational case studies isn't quite so inspirational; Patterson reacts to that information in real time. Plus: the episode opens and closes on the Trump administration's terror lists—from the maybe-imaginary Venezuelan "Cartel de los Soles" to Italy's Informal Anarchist Federation and Greece's archery-obsessed "Conspiracy of Cells of Fire". Produced by Corey Wara Email us at thegist@mikepesca.com To advertise on the show, contact ad-sales@libsyn.com or visit https://advertising.libsyn.com/TheGist Subscribe to The Gist: https://subscribe.mikepesca.com/ Subscribe to The Gist Youtube Page: https://www.youtube.com/channel/UC4_bh0wHgk2YfpKf4rg40_g Subscribe to The Gist Instagram Page: GIST INSTAGRAM Follow The Gist List at: Pesca Profundities | Mike Pesca | Substack
Free Juicebox Community (non Facebook) Type 1 Diabetes Pro Tips - THE PODCAST Eversense CGM Medtronic Diabetes Tandem Mobi ** twiist AID System Drink AG1.com/Juicebox Use code JUICEBOX to save 40% at Cozy Earth CONTOUR NextGen smart meter and CONTOUR DIABETES app Dexcom G7 Go tubeless with Omnipod 5 or Omnipod DASH * Get your supplies from US MED or call 888-721-1514 Touched By Type 1 Take the T1DExchange survey Apple Podcasts> Subscribe to the podcast today! The podcast is available on Spotify, Google Play, iHeartRadio, Radio Public, Amazon Music and all Android devices The Juicebox Podcast is a free show, but if you'd like to support the podcast directly, you can make a gift here or buy me a coffee. Thank you! *The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof. ** t:slim X2 or Tandem Mobi w/ Control-IQ+ technology (7.9 or newer). RX ONLY. Indicated for patients with type 1 diabetes, 2 years and older. BOXED WARNING:Control-IQ+ technology should not be used by people under age 2, or who use less than 5 units of insulin/day, or who weigh less than 20 lbs. Safety info: tandemdiabetes.com/safetyinfo Disclaimer - Nothing you hear on the Juicebox Podcast or read on Arden's Day is intended as medical advice. You should always consult a physician before making changes to your health plan. If the podcast has helped you to live better with type 1 please tell someone else how to find it!
Free Juicebox Community (non Facebook) Type 1 Diabetes Pro Tips - THE PODCAST Eversense CGM Medtronic Diabetes Tandem Mobi ** twiist AID System Drink AG1.com/Juicebox Use code JUICEBOX to save 40% at Cozy Earth CONTOUR NextGen smart meter and CONTOUR DIABETES app Dexcom G7 Go tubeless with Omnipod 5 or Omnipod DASH * Get your supplies from US MED or call 888-721-1514 Touched By Type 1 Take the T1DExchange survey Apple Podcasts> Subscribe to the podcast today! The podcast is available on Spotify, Google Play, iHeartRadio, Radio Public, Amazon Music and all Android devices The Juicebox Podcast is a free show, but if you'd like to support the podcast directly, you can make a gift here or buy me a coffee. Thank you! *The Pod has an IP28 rating for up to 25 feet for 60 minutes. The Omnipod 5 Controller is not waterproof. ** t:slim X2 or Tandem Mobi w/ Control-IQ+ technology (7.9 or newer). RX ONLY. Indicated for patients with type 1 diabetes, 2 years and older. BOXED WARNING:Control-IQ+ technology should not be used by people under age 2, or who use less than 5 units of insulin/day, or who weigh less than 20 lbs. Safety info: tandemdiabetes.com/safetyinfo Disclaimer - Nothing you hear on the Juicebox Podcast or read on Arden's Day is intended as medical advice. You should always consult a physician before making changes to your health plan. If the podcast has helped you to live better with type 1 please tell someone else how to find it!