Podcasts about Genome

Genetic material of organism

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Best podcasts about Genome

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Latest podcast episodes about Genome

Bass Agenda
BassAgenda 233 POLADROID interview and selections

Bass Agenda

Play Episode Listen Later Sep 25, 2023 137:55


Get shows early plus voice free bonus mix versions and more at www.patreon.com/bassagenda Check the Bass Agenda Community playlist - these guys are helping keep this thing going! soundcloud.com/bassagenda/sets/bass-agenda-community-members 4th Genome & Anon - Bass Agenda Intro Poladroid - Codex Poladroid - Kali Yuga Wars Poladroid - Rabbit Holes Cercle Futur - Anthropocene Poladroid - Homo Globalis Poladroid - Return of the Wavejumper Xenomorph Jazz Ensemble - Electronic Masada Poladroid - Civilization Suicide - Frankie Teardrop Herbie Hancock - Rain Dance Scorn - Falling (Autechre FR 13 remix) Jaguar (Alec Empire) - Weep Napalm Death - Walls of Confinement Trichome - Spat Chula Syrte - Beyond Human Hexalyne - Raecs Test Ben Milstein - Back Reel by Real - Untitled Lloyd Stellar - Digital Hallucinations (Exploited Club) T/error - You Can Only Go Forward Americhord - Frqnz Alva Recek - IPA Get shows early plus voice free bonus mix versions and more at www.patreon.com/bassagenda

Sasquatch Odyssey
SO EP:359 Bigfoot DNA

Sasquatch Odyssey

Play Episode Listen Later Sep 8, 2023 69:20


My guest tonight is Robin from South Carolina. She is here to share her pretty amazing encounters with a clan of Sasquatch that have been going on for many years. In the middle of her interview, things take an unexcpeted turn and we delve into her work on the Melba Kethchum DNA study from 2013. This is one that you do not want to miss! Sasquatch Genome Project Support Our SponsorsVisit 4 Patriots Use Promo Code SASQUATCH for 10% off your first purchase!Sasquatch Odyssey Is Sponsored By BetterHelpVisit HelloFresh Now For Your 16 Free Meals!Get Dave Here!Visit Hangar1 PublishingSasquatch Odyssey YouTube ChannelVisit Our WebsiteParanormal World Productions Merchandise Store Support The Showhttps://www.patreon.com/paranormalworldproductionsAll The Socials And Stuff/Contact Brianhttps://linktr.ee/ParanormalWorldProductionsbrian@paranormalworldproductions.com Send Brian A Voicemail Or Tell Your Storyhttps://www.speakpipe.com/SasquatchOdysseyPodcastFollow The Show On Instagram https://www.instagram.com/sasquatchodyssey/Follow The Show On TikTok https://www.tiktok.com/@sasquatchodysseypodcast?_t=8XRHQxPMFYo&_r=1This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/4839697/advertisement

RNZ: Nine To Noon
Science: Winning tickets, Beethoven's genome, brain wave music

RNZ: Nine To Noon

Play Episode Listen Later Aug 22, 2023 9:35


Science commentator Allan Blackman joins Kathryn with three great studies - one that details how many lottery tickets you'd need to buy in order to guarantee a win, another that has uncovered details about Beethoven's health through just a simple lock of his hair and how scientists reconstructed a Pink Floyd song just by using patients' brainwaves. Allan Blackman is a Professor of Chemistry, School of Science, Auckland University of Technology.

KQED’s Forum
‘Moonshot for Biology' Aims to Sequence a Genome of Every Type of Plant and Animal on Earth

KQED’s Forum

Play Episode Listen Later Aug 14, 2023 55:32


A group of scientists is racing to sequence genes from every plant, animal, and fungus on Earth for a global database of DNA. The organizers of the global Earth BioGenome Project call it a ‘moonshot for biology' which would provide a treasure trove of information on evolutionary biology, the development of medicines, the conservation of species and more. We talk with scientists about their race against time to collect genes while tens of thousands of species are threatened with extinction and what they hope will come of it. Guests: Harris Lewin, chair, the Earth BioGenome Project Executive Committee; distinguished professor Emeritus of Evolution and Ecology, the University of California, Davis Brad Shaffer, director, UCLA La Kretz Center for California Conservation Science; distinguished professor, Department of Ecology and Evolutionary Biology Sadye Paez, chair of the justice, equity, diversity and inclusion committee, the Earth BioGenome Project; collaborator on the Vertebrae Genome Project, the The Rockefeller University

The New Flesh
Jonathan Anomaly | Creating Future People | Ep. 112

The New Flesh

Play Episode Listen Later Aug 14, 2023 76:22


In this week's episode of the New Flesh Podcast, Ricky and Jon interview Jonathan Anomaly. Jonathan is the Academic Director of the Center for Philosophy, Politics, & Economics in Quito, Ecuador. Jonathan's book “Creating Future People: The Ethics of Genetic Enhancement” explores the social implications of emerging reproductive technologies, including embryo selection. Topics covered include; IVF screening, emerging reproductive technologies, embryo selection, the social and moral implications of gene editing, eugenics AND more.  ---ARTICLES AND LINKS DISCUSSED---Jonathan Anomaly official website:https://jonathan-anomaly.com/---FOLLOW THE CONVERSATION ON reddit:https://www.reddit.com/r/thenewfleshpodcast/---SUPPORT THE NEW FLESHBuy Me A Coffee:https://www.buymeacoffee.com/thenewflesh---Instagram: @thenewfleshpodcast---Twitter: @TheNewFleshpod---Follow Ricky: @ricky_allpike on InstagramFollow Ricky: @NewfleshRicky on TwitterFollow Jon: @thejonastro on Instagram---Logo Design by Made To Move: @made.tomove on InstagramTheme Song: Dreamdrive "Vermilion Lips" 

Oncotarget
Blog: Whole-Genome Doubling and Aneuploidy in Human Cancer

Oncotarget

Play Episode Listen Later Aug 10, 2023 5:33


Whole-genome doubling (WGD) and aneuploidy are two common genomic alterations that occur in human cancers. WGD is a macro-evolutionary event that results in the duplication of the entire genome, while aneuploidy is a micro-evolutionary event that results in the gain or loss of individual chromosomes or chromosome arms. Both WGD and aneuploidy can have profound effects on cellular physiology, gene expression and genome stability, and are associated with tumor initiation, progression and drug resistance. However, the relationship between WGD and aneuploidy is complex and context-dependent. In a new editorial paper, researchers Kavya Prasad and Uri Ben-David from Tel Aviv University discuss a recent study exploring how WGD shapes the aneuploidy landscape of human cancers. Their editorial was published in Oncotarget on April 26, 2023, and entitled, “A balancing act: how whole-genome doubling and aneuploidy interact in human cancer.” “It is known that tumors that have undergone WGD are more permissive to aneuploidy, but whether WGD also affects aneuploidy patterns has remained an open question.” Full blog - https://www.oncotarget.org/2023/08/10/whole-genome-doubling-and-aneuploidy-in-human-cancer/ Editorial DOI - https://doi.org/10.18632/oncotarget.28374 Correspondence to - Uri Ben-David - ubendavid@tauex.tau.ac.il Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28374 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, cancer genetics, whole-genome doubling, chromosomal instability About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: SoundCloud - https://soundcloud.com/oncotarget Facebook - https://www.facebook.com/Oncotarget/ Twitter - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Media Contact MEDIA@IMPACTJOURNALS.COM 18009220957

Vlan!
[BEST-OF] How can we solve our "meaning" crisis? with Jamie Wheal

Vlan!

Play Episode Listen Later Aug 10, 2023 85:00


Tous les étés je fais une sélection des épisodes qui m'ont le plus marqué dans l'année ou dans les années précédentes. L'occasion pour vous de retrouver une sélection resserée d'épisodes qu'il vous plaira de découvrir ou de réécouter je l'espère. Jamie Wheal est le fondateur et le directeur du "flow Genome project", une organisation internationale dédiée à la recherche et la formation autour des performances humaine. Il est également l'auteur d'un livre que j'ai littéralement adoré mais qui n'existe pas en langue française: Rethinking God, Sex and Death In a World That's Lost Its Mind. Comme vous le savez je fais très très peu d'épisodes en anglais, ce qui est assez logique pour un podcast français mais en même temps, c'est parfois frustrant quand vous avez accès à un contenu exceptionnel et que vous n'avez pas vraiment l'équivalent en français. C'est en général ce que j'essaie de faire bien sur mais dans le cas de Jamie, la manière dont il articule sa vision de la société est tellement pertinente. L'épisode, en plus d'être en anglais, est plus long que d'habitude aussi mais je suis certain que si vous comprenez la langue de Shakespeare, vous allez adorer chaque seconde de cet épisode. Nous abordons de multiples questions comme: - Pourquoi autant de personnes ont des problématiques de santé mentale? - Qu'est ce qui se passe au plan politique tant au niveau local qu'international? - Comment sommes nous arrivés dans une situation ou le monde semble tellement binaire alors que nous savons tous qu'il est très complexe? - Est-ce que notre société est en train de s'effondrer? - Comment trouver du sens à sa vie? - Comment réduire nos anxiétés? Et de nombreuses autres en réalité. J'espère que vous allez prendre autant de plaisir que moi à écouter cet épisode que j'ai vraiment ADORE!!! Suggestion d'autres épisodes à écouter : #175 Comprendre le dessous des guerres invisibles mondiales avec Thomas Gomart (https://audmns.com/DDPnQDW) #140 Comprendre le retour du magique, du sensible et de l'invisible avec Michel Maffesoli (https://audmns.com/vQszdIy) Vlan #86 La déconnexion des élites est responsable de la montée de l'extrémisme avec Michel Maffesoli (https://audmns.com/GGcksHZ)

The Osterholm Update: COVID-19
Episode 136: Perspective and Humility

The Osterholm Update: COVID-19

Play Episode Listen Later Jul 27, 2023


In "Perspective and Humility," Dr. Osterholm and Chris Dall discuss the state of the pandemic in the U.S. and internationally, a recent study on recombinant flu vaccines, and respiratory protection in healthcare settings.UN Report: Global hunger numbers rose to as many as 828 million in 2021 (WHO)From Asymptomatic COVID to Long COVID: Major Advances in Genetic Underpinnings (Eric Topol, Ground Truths)A common allele of HLA is associated with asymptomatic SARS-CoV-2 infection (Augusto et al., Nature)Genome-wide Association Study of Long COVID (Lammi et al., MedRxiv)Genetic Risk Factors for Severe and Fatigue Dominant Long COVID and Commonalities with ME/CFS Identified by Combinatorial Analysis (Taylor et al., MedRxiv)Vaccine effectiveness of recombinant and standard dose influenza vaccines against influenza related hospitalization using a retrospective test-negative design (Zimmerman et al., Vaccine)

Innovation Ambassadors
Episode 36: AWS Innovation with the Genome Institute of Singapore (GIS)

Innovation Ambassadors

Play Episode Listen Later Jul 21, 2023 15:36


Hear about GIS's collaboration with the AWS prototyping team, which has enabled seamless integration and access to vast amounts of genomic data within a secure and scalable framework.

THE EMBC NETWORK featuring: ihealthradio and worldwide podcasts
Deep Nutrition: Unlocking Your Genome, Good Fats Vs Bad Fat (Part 1 of 3)

THE EMBC NETWORK featuring: ihealthradio and worldwide podcasts

Play Episode Listen Later Jul 18, 2023 32:47


This is the first of a three part episode, where I am going to dissect some key nutrition concepts. After reading the book, Deep Nutrition, several years ago, I had learned so much about how our nutrition effects our genes, our symmetry, and much more. Even if you didn't read the book, there were a few main take-aways, that if you only did these things, you could lead a much healthier, vibrant, and disease-free life. Further, I see so many people making a huge mistakes when it comes to the types of oils they should be using and it makes me cringe. The problem is, it's not your fault. The media along with several governmental groups such as the American Heart Association (AMA) and the Federal Drug Administration (FDA) have led people astray since the 1960's. With so much time overlapped, people just continue to do what generations before them have done, or they just don't know any better because the new, real science is not being promoted. These are easy fixes, but if not addressed, 30 years will pass and you'll be on six different medications for your blood pressure, cholesterol, and sexual performance. In this episode I talk about heart disease, cholesterol, LDL vs HDL, good fats vs bad fats, and the history of this science. It's ironic as at the time of creating this episode, other doctors and wellness warriors are trying to tell the other side of the coronavirus pandemic, and they are being silenced and censored by the mainstream media, as well as social media outlets. In the 1960's, the same type of censorship was orchestrated, and Americans were told to change thier diet, eat certain foods, and heart disease which was at all time lows skyrocketed. And so did the pocketbooks of Big Pharma. Enjoy the episode!If you're looking to go deep in your life, and you're interested in improving your health or reaching higher levels in your life, please contact me for one on one coaching at info@joelevancoaching.com

THE EMBC NETWORK featuring: ihealthradio and worldwide podcasts
Deep Nutrition: Unlocking Your Genome, Good Fats Vs Bad Fat (Part 1 of 3)

THE EMBC NETWORK featuring: ihealthradio and worldwide podcasts

Play Episode Listen Later Jul 18, 2023 32:47


This is the first of a three part episode, where I am going to dissect some key nutrition concepts. After reading the book, Deep Nutrition, several years ago, I had learned so much about how our nutrition effects our genes, our symmetry, and much more. Even if you didn't read the book, there were a few main take-aways, that if you only did these things, you could lead a much healthier, vibrant, and disease-free life. Further, I see so many people making a huge mistakes when it comes to the types of oils they should be using and it makes me cringe. The problem is, it's not your fault. The media along with several governmental groups such as the American Heart Association (AMA) and the Federal Drug Administration (FDA) have led people astray since the 1960's. With so much time overlapped, people just continue to do what generations before them have done, or they just don't know any better because the new, real science is not being promoted. These are easy fixes, but if not addressed, 30 years will pass and you'll be on six different medications for your blood pressure, cholesterol, and sexual performance. In this episode I talk about heart disease, cholesterol, LDL vs HDL, good fats vs bad fats, and the history of this science. It's ironic as at the time of creating this episode, other doctors and wellness warriors are trying to tell the other side of the coronavirus pandemic, and they are being silenced and censored by the mainstream media, as well as social media outlets. In the 1960's, the same type of censorship was orchestrated, and Americans were told to change thier diet, eat certain foods, and heart disease which was at all time lows skyrocketed. And so did the pocketbooks of Big Pharma. Enjoy the episode!If you're looking to go deep in your life, and you're interested in improving your health or reaching higher levels in your life, please contact me for one on one coaching at info@joelevancoaching.com

The Science of Self Healing with Dr. Sharon Stills
Podcast #111 - How Cutting-Edge DNA Sequencing is Personalising Health and Wellbeing|Andreanna Rainville, RN, NC, Scientific Advisor

The Science of Self Healing with Dr. Sharon Stills

Play Episode Listen Later Jul 18, 2023 49:39


Dr. Sharon Stills interviews Andreanna Rainville (“Nurse Andi”), RN, NC, Scientific Advisor about a cutting-edge technology: using DNA sequencing to analyze genetic differences that we, as consumers, can take action to address. Nurse Andi is the scientific advisor for SNIP Nutrigenomics, and she explains how her company empowers people to take control of their health through personalized medicine. SNIP Nutrigenomics analyzes DNA for common mutations; creates actionable, personalized genetic reports; and even develops custom, personalized supplements to optimize gene functions. If you are looking for an incredible way to enhance your wellbeing, you won't want to miss this podcast!

I AM BIO
The New Age of CRISPR (Redux)

I AM BIO

Play Episode Listen Later Jul 18, 2023 27:40


CRISPR has emerged as a powerful tool for altering DNA sequences with incredible precision, opening up new avenues of research into the treatment of disease. In this episode, we explore the science behind CRISPR, as well as its potential. From curing genetic disorders to creating new crop varieties, the possibilities seem endless. Our four guests today are scientists working to push these gene editing tools to the next frontier.

Fertility and Sterility On Air
Fertility and Sterility On Air - Live from ESHRE 2023 - Part 2

Fertility and Sterility On Air

Play Episode Listen Later Jul 16, 2023 78:51


Fertility & Sterility comes to you from ESHRE 2023 in Copenhagen, Denmark! Continuing from Part 1, listen in as we discuss some of the best abstracts from the conference. Topics in Part 2 include sperm genome editing by CRISPR-Cas9 (Angela Bryanne De Jesus - 00:42); differences in uterine contractility in women with adenomyosis (Sophie Thomas - 11:22), the effect of THC on the human sperm function (Lydia Wehrli - 22:38); the role of aberrant recombination in the origins of aneuploidy (Svetlana Madjunkova - 31:15); the quality of information generated by ChatGPT to answer patients questions about fertility (Kiri Beilby - 43:32); a trial using transdermal testosterone prior IVF in women with poor ovarian response (Nikolas Polyzos 50:14); the reproductive potential of 1pn embryos (Clare Ussher - 57:09) and using menstrual blood to evaluate the uterine immune system in patients with recurrent pregnancy loss and unexplained infertility (Kilian Vomstein & Pia Egerup - 01:08:05). View Fertility and Sterility at https://www.fertstert.org/

Chasing Consciousness
Wai H Tsang - FRACTAL BRAIN THEORY

Chasing Consciousness

Play Episode Listen Later Jul 15, 2023 90:25


What does symmetry and self-similarity between life and intelligence mean for the nature of reality? How are neurones like genes?  Today we have the extraordinary Fractal Brain Theory to discuss. After episode #38 about the World as a Neural Network, with Russian physicist and computer scientist Vitaly Vanchurin, i've become more open to a unified theory of universe that reconciles quantum mechanics with general relativity, as Vanchurin's equations seem to offer. So when I was recommended today's guest's Fractal Brain Theory by one of the wonderful listeners, I was curious if a little sceptical given all the psychedelic hype about fractal geometry. So a symmetrical theory of repeating self-similar, self-modifying behaviour in the universe is not so far from the vision of the universe as a thriving, adaptable neural network. And according to today's guest the symmetry directly connects the often divorced worlds of neurones, brains and intelligence with the world of genes, evolution and life.  He is multi-disciplinary researcher, computer scientist, musician and author Wai H Tsang. A self-taught thinker in the world of neurology, evolutionary biology, consciousness and philosophy of mind, Tsang is in the unique position of combining these traditions into a single theory of brain, that promises to solve even the hard problem of consciousness. Trained in computer science at Imperial college, he wrote the first version of his Fractal Brain Theory in 2016, in his book of the same name, and it was picked up by quantum consciousness theorist Stuart Hameroff, who invited him to the Science of Consciousness Conference, alongside heavy weights in the field like David Chalmers, Roger Penrose, Sue Blackmore,  Donald Hoffman - many who've been on this show already. This recognition catapulted his theory into the field, so it's with great pleasure that I include it on the show for us to compare alongside the theories of many of the giants. What we discuss: 00:00 Intro 07:10 Symmetry explained: Variance and non-variance; change and resistance to change 11:00 Genomes work like tiny fractal brains 12:30 The symmetry between intelligence and life, neurones and genes 13:00 Junk DNA, neurones and boolean algebra 17:45 Dendritic structure, processing and artificial intelligence 19:00 Self-similarity and recursively nested symmetry 21:30 Evolution and ontogenesis algorithm: differentiate, select, amplify  22:15 Fractal Mathematics and Benoit Mandelbrot: Approximate self-similarity 25:45 Binary trees generating life and intelligence 29:00 Mitosis and progenator fields 30:00 Allocentric and egocentric mapping (Nobel prize) 34:40 Goodwin and cell division VS epigenetic mutation/adaptation 36:00 Recursive modification IS intelligence; evolving evolvability 40:15 A new calculus: analytic geometry  47:00 The soft and hard problem of consciousness  51:00 Time symmetric quantum mechanics and problems with causal chains  58:00 David Chalmers: Identity cosmo-psychism critique 01:11:00 Is self-reflective conscious Ai possible? 01:19:30 Penrose: Quantum mechanics is incomplete until we understand the collapse of the wave function 01:21:00 The ethical debate about the future of Ai References: ‘The Fractal Brain Theory' Wai Tsang Wai Tsang You Tube Channel  Boolean Algebra David Chalmers, “Idealism and the mind body problem” paper

Mark and Pete
Serving up the perfect strawberry for Wimbledon.

Mark and Pete

Play Episode Listen Later Jul 1, 2023 10:18


A farm in England are developing the perfect strawberry to eat at the Wimbledon Tennis Championships. Marion Regan's family business started in 1893 when Bernard Champion arrived just over 31 miles away from Wimbledon in Mereworth with an ambition to become a leading fruit grower. Wild strawberries flourished in the local woods so he planted his first crop that year. Now farming approximately 500 hectares Hugh Lowe Farms, under the guidance of Marion, are one of the largest soft fruits growers in the UK.

Living Beyond 120
Why You Can't Get There Without Genetics and Where to Start

Living Beyond 120

Play Episode Listen Later Jun 22, 2023 73:45


What must you look at to optimize your health and live younger for longer? Join Dr. Jeffrey Gladden, Steve Reiter, and Joe Cohen in this episode of the Gladden Longevity Podcast. Cohen experienced various health issues, such as inflammation, brain fog, fatigue, and digestive problems, which were poorly understood in traditional healthcare. Determined to find better solutions, he delved into learning about his DNA and tracking biomarkers to improve his health. This personalized approach enabled him to optimize his well-being to a level he never imagined. Inspired by his own success, Joe founded SelfDecode, the first direct-to-consumer DNA analyzer and precision health tool. SelfDecode offers accurate insights and health recommendations by utilizing AI-driven polygenic risk scoring. With over 100,000 people benefiting from SelfDecode, Joe aims to empower individuals to embrace precision health and unlock insights from their DNA and biomarkers for optimal well-being. This episode discussed health optimization, genetics, and data's role in well-being. He covered biological age, reversing it with genes and lab data. Joe also emphasized data's importance over traditional beliefs and genetics' role in understanding the body, longevity, atherosclerosis, and polygenic risk scoring, and he shared experiences with testosterone, lab tests, health optimization framework, and addressing food sensitivities. Is there a one size fits all health solution?  Listen to this episode to learn about making 100 the new 30, and living young for a lifetime!  -- DISCOUNT:  Use GLADDEN for 10% off any plan on your genetic testing at www.selfdecode.com  --   Dr. Gladden welcomes everyone to the podcast. (2:10)  Learning to surf on a paddle board with Dr. Gladden. (02:31)  Dr. Gladden says Joe is an accomplished individual. (3:10)  Joe highlights the importance of good mood, energy, immunity, body, sleep, and social interactions. (06:09)  Dr. Gladden asks Joe what instigated him to do genetic testing. (8:02)  Dr. Gladden wants to know when Joe started doing DNA testing. (10:20)  Joe shares that the critical missing piece of biochemistry is genetics. (13:18)  Genetic testing refines patient care options. (14:30)  Genetic testing needs high-quality sampling.  (16:32)  How do I improve my health? What should I do? (18:08)  Genetics affects how our body responds. (20:55)  The functional medicine movement is moving towards looking at individual variants and prescribing based on individual variants. (22:09)  Joe says other companies are looking at a few generic variants. (24:46)  The algorithm tested on public data predicts diagnoses. (26:04)  Joe highlights what they do differently by sharing about imputation. (28:55)  There is no 80/20 rule in science. (31:17)  Genome sequencing found carrier traits; low impact. (33:00)  Dr. Gladden commends Joe's company for reporting details in a way that is actually usable. (35:59)  Joe explains how risk scores and recommendations work. (37:30)  Joe touches on how genetics are really good as foundational data. (39:53)  Genetics aren't destiny, and they adapt to the environment. (41:31)  Dr. Gladden says knowing your blueprint is one thing and how it has been expressed is another one. (43:19)  Joe notes that cardiovascular disease is a big killer. (45:25)  Tests superseded by reverse cholesterol transport method. (46:20)  Cardiovascular report: top recommendations, genetic variants. (49:37)  You can do a test for any marker that is of interest to you. (52:44)  TMAO is made by bacteria in the gut, and your diet determines the level. (54:00)  Get summary reports for personalized health journeys. (56:04)  Biology has to be balanced, and it's about getting the dose and frequency right. (59:20)  Lack of security and privacy in companies. (01:02:50)  Joe reveals that they have someone that focuses on data compliance. (1:04:26)  DNA testing varies in accuracy and algorithm.  (01:07:31)  Joe emphasizes how their algorithm is better. (1:09:05)  Dr. Gladden talks about where his parents came from. (1:11:39)           Visit our website, www.gladdenlongevitypodcast.com, for more information on this episode and other episodes as well. Click on the link to let us know what you'd like us to talk about on the podcast too!                         Follow us on social media!                                   Instagram: @gladdenlongevity                                   Twitter: @gladdenlongevit                                   Facebook: @GladdenLongevity                            LinkedIn: @GladdenLongevity       For more information on our practice or how to become a client, visit:  www.gladdenlongevity.com    Call us: 972-310-8916  Or email us: info@gladdenlongevity.com    To learn more about Joe Cohen, check out the following:  Website: https://selfdecode.com/  https://thejoecohenshow.com/  https://selfhacked.com/  Instagram: https://www.instagram.com/mrbiohacker/ (@mrbiohacker)  https://www.instagram.com/selfdecode/?hl=en (@selfdecode)  Facebook: https://www.facebook.com/selfdecode/ (@SelfDecode)  Twitter: https://twitter.com/thejoecohenshow (@thejoecohenshow)  LinkedIn: https://www.linkedin.com/company/selfdecode/ (@SelfDecode)  YouTube: https://www.youtube.com/@thejoecohenshow/about  TikTok: https://www.tiktok.com/@thejoecohenshow (@thejoecohenshow)

Clinical Chemistry Podcast
Polygenic Risk Scores: Genomes to Risk Prediction

Clinical Chemistry Podcast

Play Episode Listen Later Jun 13, 2023 13:09


predictions genome polygenic risk scores
Filling the Sink
What makes us human? Catalonia's role in biggest ever primate genome study

Filling the Sink

Play Episode Listen Later Jun 9, 2023 21:50


The most comprehensive investigation into primate genomes, recently published, shed new light on features of primate evolution, human disease and biodiversity conservation. Filling the Sink chats to some of the researchers in Catalonia that played their part in this groundbreaking international study: Tomàs Marquès-Bonet from the Institute of Evolutionary Biology at Pompeu Fabra University, and Ivo Gut, director of CNAG, the National Center for Genomic Analysis. This week's Catalan phrase is 'fer el mico.' Literally, 'to do the monkey,' it means to act silly, horse around, monkey around. Presented by Lorcan Doherty with Cristina Tomàs White, Kate Naessens and Guifré Jordan.   

Just Be® ~ Spiritual BOOM
Ep 70: w/Poetic Vanguard Sacha Stone: His History, Audit Urself, Universal Genome, 2030, New Earth Sanctuary

Just Be® ~ Spiritual BOOM

Play Episode Listen Later Jun 7, 2023 66:42


Internationally recognized through his decades of peace and justice-oriented work, Sacha Stone is today's guest. We get to hear about the beginning of his life in war-torn Rhodesia-Zimbabwe, his time in rock & roll which set the stage for caring about humanity and the Earth as well as current projects, the universal genome and the state of the world.I lead the Just Be Practice at the end which starts off with some discussion about Target and ends with peaceful and connective meditation.Links to Sacha Stone:SachaStone.com LazarusInitiative.com AriseGuerrillaNews.com NewEarthHorizon.com Commission.itnj.org Traciaunita.ro/ro/home Latest interviews: SachaStone.com/media**Host Eden Koz is a psychological empath, intuitive, medium, meditation master & dimensional as well as a galactic healer. She does remote & face-to-face sessions with groups as well as individuals.Contact info for Eden Koz / Just Be®, LLC:Insta, FB, LinkedIn, BitChute, Rumble, YouTube, Odysee, TruthSocialWebsite: EdenJustBe.comEmail: eden@edenjustbe.comProducts I endorse to help you through this Great Awakening:• Hooga: 12% off all healing products from grounding to red light therapy. Link here and enter EDENJUSTBE at checkout.• Purium Health: For vaccine healing, regret or issues – 4 products here. 25% discount ...

Trend Following with Michael Covel
Ep. 1186: Leroy Hood Interview with Michael Covel on Trend Following Radio

Trend Following with Michael Covel

Play Episode Listen Later Jun 5, 2023 50:02


My guest today is Leroy Hood, a world-renowned scientist and recipient of the National Medal of Science in 2011. He co-founded the Institute for Systems Biology (ISB) in 2000, served as its first President from 2000-2017, and is a Professor and Chief Strategy Officer. Dr. Hood was a faculty member at Caltech, serving for 10 years as the Chair of Biology. During this period, he and his colleagues developed four sequencer and synthesizer instruments that paved the way for the Human Genome Project's successful mapping and understanding of the human genome. He and his students also deciphered many of the complex mechanisms of antibody diversification. In 1992, Dr. Hood founded and chaired the Department of Molecular Biotechnology at the University of Washington, the first academic department devoted to cross-disciplinary biology. The topic is his book The Age of Scientific Wellness. In this episode of Trend Following Radio we discuss: Health care opportunities Phenotypic traits
 Three components of health trajectory
 Genome discussion Obesity
 Jump in! --- I'm MICHAEL COVEL, the host of TREND FOLLOWING RADIO, and I'm proud to have delivered 10+ million podcast listens since 2012. Investments, economics, psychology, politics, decision-making, human behavior, entrepreneurship and trend following are all passionately explored and debated on my show. To start? I'd like to give you a great piece of advice you can use in your life and trading journey… cut your losses! You will find much more about that philosophy here: https://www.trendfollowing.com/trend/ You can watch a free video here: https://www.trendfollowing.com/video/ Can't get enough of this episode? You can choose from my thousand plus episodes here: https://www.trendfollowing.com/podcast My social media platforms: Twitter: @covel Facebook: @trendfollowing LinkedIn: @covel Instagram: @mikecovel Hope you enjoy my never-ending podcast conversation!

Smart Business Dealmakers
Megan Bailey, former CEO of Personal Genome Diagnostics

Smart Business Dealmakers

Play Episode Listen Later Jun 2, 2023 33:18


In 2022, Labcorp paid a reported $450 million to acquire Personal Genome Diagnostics, known as PGDx, a genomic testing company. Megan Bailey, who was CEO of PGDx, stops by the pod to offer a peek inside the deal — what it was like building the deal team, getting buy-in, how they chose Labcorp and why they pursued a sale after successfully raising a $103 million Series C earlier that same year.

UNTOLD RADIO AM
The Sasquatch Outpost #15 Sasquatch Genome Revisited

UNTOLD RADIO AM

Play Episode Listen Later May 31, 2023 132:06


This is a Special Episode. Four members of the Sasquatch Genome Project come together again for the first time since 2013. What was the Genome project? What were they trying to achieve? What results came out of the study?Please subscribe and hit the notification bell, so you will never miss a new show or any of the 7 other amazing shows that are launching soon!

Tune in Live at 7 PM Central, 8 PM Eastern, 5 PM Pacific Coast, and 6 PM Mountain Time.

SUBSCRIBE and support our efforts to entertain and inform. Without your free subscription, we will not survive.

Check Out Other Amazing Shows on the Untold Radio Network: Untold Radio AM, Bigfoot Influencers, Pine Island Research, Down Under Anomalies and many more!This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/4602609/advertisement

Machine Learning Street Talk
Decoding the Genome: Unraveling the Complexities with AI and Creativity [Prof. Jim Hughes, Oxford]

Machine Learning Street Talk

Play Episode Listen Later May 31, 2023 42:57


Support us! https://www.patreon.com/mlst MLST Discord: https://discord.gg/aNPkGUQtc5 Twitter: https://twitter.com/MLStreetTalk In this eye-opening discussion between Tim Scarfe and Prof. Jim Hughes, a professor of gene regulation at Oxford University, they explore the intersection of creativity, genomics, and artificial intelligence. Prof. Hughes brings his expertise in genomics and insights from his interdisciplinary research group, which includes machine learning experts, mathematicians, and molecular biologists. The conversation begins with an overview of Prof. Hughes' background and the importance of creativity in scientific research. They delve into the challenges of unlocking the secrets of the human genome and how machine learning, specifically convolutional neural networks, can assist in decoding genome function. As they discuss validation and interpretability concerns in machine learning, they acknowledge the need for experimental tests and ponder the complex nature of understanding the basic code of life. They touch upon the fascinating world of morphogenesis and emergence, considering the potential crossovers into AI and their implications for self-repairing systems in medicine. Examining the ethical and regulatory aspects of genomics and AI, the duo explores the implications of having access to someone's genome, the potential to predict traits or diseases, and the role of AI in understanding complex genetic signals. They also consider the challenges of keeping up with the rapidly expanding body of scientific research and the pressures faced by researchers in academia. To wrap up the discussion, Tim and Prof. Hughes shed light on the significance of creativity and diversity in scientific research, emphasizing the need for divergent processes and diverse perspectives to foster innovation and avoid consensus-driven convergence. Filmed at https://www.creativemachine.io/Prof. Jim Hughes: https://www.rdm.ox.ac.uk/people/jim-hughesDr. Tim Scarfe: https://xrai.glass/ Table of Contents: 1. [0:00:00] Introduction and Prof. Jim Hughes' background 2. [0:02:48] Creativity and its role in science 3. [0:07:13] Challenges in understanding the human genome 4. [0:13:20] Using convolutional neural networks to decode genome function 5. [0:15:32] Validation and interpretability concerns in machine learning 6. [0:17:56] Challenges in understanding the basic code of life 7. [0:19:36] Morphogenesis, emergence, and potential crossovers into AI 8. [0:21:38] Ethics and regulation in genomics and AI 9. [0:23:30] The role of AI in understanding and managing genetic risks 10. [0:32:37] Creativity and diversity in scientific research

Lex Fridman Podcast
#380 – Neil Gershenfeld: Self-Replicating Robots and the Future of Fabrication

Lex Fridman Podcast

Play Episode Listen Later May 28, 2023 131:20


Neil Gershenfeld is the director of the MIT Center for Bits and Atoms. Please support this podcast by checking out our sponsors: - LMNT: https://drinkLMNT.com/lex to get free sample pack - NetSuite: http://netsuite.com/lex to get free product tour - BetterHelp: https://betterhelp.com/lex to get 10% off EPISODE LINKS: Neil's Website: http://ng.cba.mit.edu/ MIT Center for Bits and Atoms: https://cba.mit.edu/ Fab Foundation: https://fabfoundation.org/ Fab Lab community: https://fablabs.io/ Fab Academy: https://fabacademy.org/ Fab City: https://fab.city/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: - Check out the sponsors above, it's the best way to support this podcast - Support on Patreon: https://www.patreon.com/lexfridman - Twitter: https://twitter.com/lexfridman - Instagram: https://www.instagram.com/lexfridman - LinkedIn: https://www.linkedin.com/in/lexfridman - Facebook: https://www.facebook.com/lexfridman - Medium: https://medium.com/@lexfridman OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) - Introduction (05:37) - What Turing got wrong (11:02) - MIT Center for Bits and Atoms (24:08) - Digital logic (30:44) - Self-assembling robots (41:12) - Digital fabrication (52:07) - Self-reproducing machine (59:53) - Trash and fabrication (1:04:49) - Lab-made bioweapons (1:09:04) - Genome (1:20:56) - Quantum computing (1:25:28) - Microfluidic bubble computation (1:30:49) - Maxwell's demon (1:39:35) - Consciousness (1:46:35) - Cellular automata (1:51:07) - Universe is a computer (1:55:53) - Advice for young people (2:05:10) - Meaning of life

Whale Tales Podcast
Episode 051-Type D Killer Whale Genomes

Whale Tales Podcast

Play Episode Listen Later May 24, 2023 34:58


Journal club is back! We are talking about the new paper “Type D” killer whale genomes reveal long-term small population size and low genetic diversity from Dr. Andrew Foote et al. Show Notes: Read the full paper! https://academic.oup.com/jhered/article/114/2/94/7086686 More about Dr. Foote https://orcid.org/0000-0001-7384-1634

Empowered Nutrition
How AI-Derived Genetic Testing Can Optimize Your Health with Dr. Yael Joffe

Empowered Nutrition

Play Episode Listen Later May 24, 2023 50:25


Curious about genetic testing and how beneficial it can be for your health? No…we're not talking about the ancestry testing that told you that you are 99.9% likely to prefer vanilla ice cream over chocolate. On this week's podcast, I have the pleasure of talking about nutrigenetics with Dr. Yael Joffe, the founder of 3x4 genetics! Think of your genetics as a blueprint that gives you an idea of who you are and how you respond to the world around you. Nutrigenetics, as you have put together is personalized nutrition based on our genetics and how our DNA influences the choices we make in life. Why start your healthcare journey with a genetic test? You only have to test once in your lifetime because genes don't change! What changes is how genes switch on and off based on our environment. How is this test different from another DNA test? 3x4 uses root cause analysis to view pathways that affect the cell (inflammation, metabolism, and detoxification processes) and groups together multiple genes and using a polygenetic risk score to measure your disease risk based on your genome. This week, Dr. Yael Joffe and I discuss: · FOUR ways genetics can be used as a screening tool: Helps you know which area of health to focus from the beginning. Results that give the most personalized lifestyle and nutrition protocol (with the help of a qualified       clinician) Allows you to determine specific lab values to follow up with Allows for targeted supplementation – choosing the supplements with the greatest impact on your health. · Red flags and questions to ask the genetic testing companies. · And so much more! Interested in ordering a 3x4 test with Empowered Nutrition? Click here.   Want to learn more about 3x4 genetics whether you are a clinician or a client? Get to know your genes at https://3x4genetics.com or email your questions to info@3x4genetics.com.   Interested in our Lean for Life Membership? Help yourself feel aligned using our three phase approach: Lean for Life Membership called Heal, Optimize , and Refinewhere you will be empowered to reverse previous metabolic damage with the assistance of our team of Registered Dietitian Nutritionists. Check out more details on our website! Want to learn more about our one-on-one Empowered Nutrition coaching? Book a free chemistry call to discuss your story and see if we're a good fit. Enjoying the podcast? Please review the Empowered Nutrition Podcast on Apple Podcasts or wherever you listen! Then, send me a screenshot of your positive review to podcast@empowerednutrition.health as a DM on Instagram (@empowerednutrition.health).Include a brief description of what you're working on with your health and/or nutrition and I'll send you a free custom meal plan! Do you have questions you would like answered on the Empowered Nutrition podcast? You can propose your questions/ideas here or reach out to me at podcast@empowerednutrition.health

Science & Technology - Voice of America
Modern Genome Data Suggests How Homo Sapiens Developed in Africa - May 22, 2023

Science & Technology - Voice of America

Play Episode Listen Later May 22, 2023 5:26


AI and the Future of Work
Guru Banavar, founding CTO of Viome and former VP of IBM Watson AI, discusses the future of personalized healthcare using AI and your microbiome

AI and the Future of Work

Play Episode Listen Later May 22, 2023 40:56


Guru Banavar is the founding CTO of Viome where he helped raise $150M from a list of top-tier investors including Khosla Ventures and Bold Capital Group. Viome offers insights into health and disease using host and microbiome gene expression. Guru led the development of a first-of-a-kind saliva-based early detection system for oral and throat cancers which won the FDA's designation as a breakthrough device.Prior to Viome, Guru was a global VP & Chief Science Officer at IBM and the founding VP of the Watson AI Research team.Guru has received many awards including a Leadership in Technology Management Award and a National Innovation Award from the President of India. He has published extensively and holds more than 35 US patents. His work has been featured in media outlets including the New York Times, the Economist, the Wall Street Journal, BBC, and NPR.Listen and learn… Why our healthspan is more important than our lifespan How DNA to RNA transcription determines your health state How to sequence your mRNA to understand how to optimize your diet and predict disease risk What AI techniques can be used to develop personalized treatments How to use data that varies across patients to make automated decisions for all patients How Guru thinks about false positive prescriptions as a scientist when health and safety are at stake Where the FDA is regulating how AI is used to make healthcare recommendations Why it's impossible to know the best diet for you without first understanding the composition of your microbiome How to use biomarkers to turn your biological fingerprint into a data problem Guru's perspective on the ethical and philosophical implications of extending the healthspan How digital twins will help perfect the ability to engineer biology References in this episode… What it means to practice responsible AIThe KEGG ontology of biological pathways The Viome blog Dr. Shiv Rao, CEO of Abridge, on AI and the Future of Work

Unsugarcoated with Aalia and Alex
E95 Want to Live Long? Get Tech About It!

Unsugarcoated with Aalia and Alex

Play Episode Listen Later May 19, 2023 35:47


In our final episode of season 11, Aalia is joined by Johannes Bhakdi, the Founder and CEO of Quantgene. Jo brings his expertise in the biotech industry as they discuss the use of AI and genomics in preventative healthcare, to aid in the early detection and prevention of diseases. They also talk about the role emotional intelligence plays in the industry. Jo highlights the potential of genomics and AI in developing personalized treatment plans and bridging gaps in healthcare access. He also shares Quatgene's goals to make preventative care more accessible to all, and extend the healthy human lifespan by a decade within the next decade. Like, comment, and subscribe! Stay connected with your host on IG: @aalia_unsugarcoated Stay connected to our guest: @quantgene UNSUGARCOATED™ Media is a 501c3 media enterprise, using podcasts, print publications, short documentaries, and more to tell stories of empowerment in the face of adversity and trauma. For more information on our goals, content, and sponsorship opportunities, please visit our website.

Quirks and Quarks Complete Show from CBC Radio
Antarctic dinosaur migration, permafrost and pollution, tracking shark births, Moana's tools, the Pangenome, and Zoonomia mammalian genome projects

Quirks and Quarks Complete Show from CBC Radio

Play Episode Listen Later May 19, 2023 53:44


Giant dinosaurs found in Australia migrated through Antarctica; A map of arctic industrial pollution shows where risks might arise as permafrost melts; A new technology is showing where baby sharks are born; Polynesian tool finds support the oral histories behind Moana; Incorporating diversity of human genomes in new Pangenome; Comparing 240 mammalian genomes helps illuminate what makes us human.

The Tip Touch Podcast
#131 | Eduardo and Brett | Genome Mod

The Tip Touch Podcast

Play Episode Listen Later May 19, 2023 62:34


Beyond Expectation Podcast talk about what's really going on in the world. Eduardo and Brett come out swinging. From Bigfoot to the White House, UAPs to local musicians, there is nothing Beyond Expectation for these two. Reach out to us on the soshul meediaz like Instagram to tell us what you think. Are you someone with an interesting story to tell? Let us know! Socials: [Beyond Expectation Podcast] Brett Otto & Eduardo Osorio (@beyondexpectationpodcast) • Instagram photos and videos [Eduardo] Eduardo Osorio Garcia (@edu_ardoe) • Instagram photos and videos Be sure to follow Eduardo on twitch.tv/maggpack. For more exclusive updates and future content of the world's newest best podcast ever you can follow on Instagram @beyondexpectationpodcast. Help us grow by subscribing to the podcast on platforms such as Apple Podcasts, Google Play, Spotify, Stitcher and TuneIn. 5-star reviews are greatly appreciated. As always, thank you for your support.

Field, Lab, Earth
Global Reliance on Corn Belt Dent with Dr. Stephen Smith

Field, Lab, Earth

Play Episode Listen Later May 19, 2023 53:34


“Global Dependence Upon Corn Belt Dent Maize Germplasm: Challenges and Opportunities” with Dr. Stephen Smith, Affiliate Professor at Iowa State University Plant breeders are constantly trying to find the best crosses to increase the traits farmers and consumers want. However, continually crossing the same varieties can decrease the genetic gene pool over time, making plants susceptible to certain pests, diseases, and other stressors. To help understand the depth of the gene pool and to better understand how reliant we are on certain crop varieties, Dr. Stephen Smith and his team attempted to survey which maize varieties are bred and used the most. On this episode, we dive deep to discover what his team turned up. Tune in to learn: ·         What obstacles can exist for researchers trying to gather worldwide breeding data ·         Why pre-breeding is a crucial complement to the newest tech ·         Which countries keep the best maize breeding records ·         How reliant we are on certain maize varieties If you would like more information about this topic, this episode's paper is available here: https://doi.org/10.1002/csc2.20802 This paper is always freely available. Contact us at podcast@sciencesocieties.org or on Twitter @FieldLabEarth if you have comments, questions, or suggestions for show topics, and if you want more content like this don't forget to subscribe. If you'd like to see old episodes or sign up for our newsletter, you can do so here: https://fieldlabearth.libsyn.com/. If you would like to reach out to Stephen, you can find him here: Stephen.Smith@mchsi.com If you would like to reach out to Yaswant Kumar Pankaj from our Student Spotlight, you can find him here: yaswant19994@tamu.edu https://www.linkedin.com/in/yaswant-kumar-pankaj-0535a6b5/ Resources CEU Quiz: https://web.sciencesocieties.org/Learning-Center/Courses/Course-Detail?productid=%7b78BCC3E2-26F4-ED11-8848-000D3A3236E0%7d  Transcripts: https://www.rev.com/transcript-editor/shared/XunXbxbDXPOL_SGYM4hFfmQRtjA0BVjche4ujk1Wjw4toMH709hcD0tG7Rukmx9gPzcqtSzuxkAsYSgTSl9u3Z4ZDa4?loadFrom=SharedLink  CIMMYT: https://www.cimmyt.org/ USDA Plant Introduction Research Station: https://www.ars.usda.gov/midwest-area/ames/plant-introduction-research/ National Plant Germplasm System: https://www.ars-grin.gov/npgs/ Crop Trust: https://www.croptrust.org/ Sponsored by METER Group. METER sensors deliver real-time, plant, soil, and atmospheric data that fuels environmental research. Listen to METER Group's new podcast We Measure the World to hear how innovative researchers leverage environmental data to make our world a better—and more sustainable—place at metergroup.com/fieldlabearth Field, Lab, Earth is Copyrighted by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America.

Epigenetics Podcast
scDamID, EpiDamID and Lamina Associated Domains (Jop Kind)

Epigenetics Podcast

Play Episode Listen Later May 17, 2023 51:08


In this episode of the Epigenetics Podcast, we caught up with Jop Kind from Hubrecht Institute to talk about his work on single cell DamID, EpiDamID, and Lamina Associated Domains (LADs). Jop Kind started out developing single cell DamID (scDamID), based on the DamID technique. First, this technique was adapted to a microscopic readout which enabled them to follow the localisation of chromatin domains after cell division. Next, the lab expanded this technique into the NGS space and created genome-wide maps of nuclear lamina Interactions in single human cells. Since LADs are in a heterochromatic chromatin context, the lab expanded scDamID into the epigenetic space. They first combined it with a transcriptional readout.  Later-on they developed EpiDamID, a method to target a diverse set of chromatin types by taking advantage of the binding specificities of single-chain variable fragment antibodies, engineered chromatin reader domains, and endogenous chromatin-binding proteins.   References Kind, J., Pagie, L., Ortabozkoyun, H., Boyle, S., de Vries, S. S., Janssen, H., Amendola, M., Nolen, L. D., Bickmore, W. A., & van Steensel, B. (2013). Single-Cell Dynamics of Genome-Nuclear Lamina Interactions. Cell, 153(1), 178–192. https://doi.org/10.1016/j.cell.2013.02.028 Kind, J., Pagie, L., de Vries, S. S., Nahidiazar, L., Dey, S. S., Bienko, M., Zhan, Y., Lajoie, B., de Graaf, C. A., Amendola, M., Fudenberg, G., Imakaev, M., Mirny, L. A., Jalink, K., Dekker, J., van Oudenaarden, A., & van Steensel, B. (2015). Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells. Cell, 163(1), 134–147. https://doi.org/10.1016/j.cell.2015.08.040 Borsos, M., Perricone, S.M., Schauer, T. et al. Genome–lamina interactions are established de novo in the early mouse embryo. Nature 569, 729–733 (2019). https://doi.org/10.1038/s41586-019-1233-0 Markodimitraki, C. M., Rang, F. J., Rooijers, K., de Vries, S. S., Chialastri, A., de Luca, K. L., Lochs, S. J. A., Mooijman, D., Dey, S. S., & Kind, J. (2020). Simultaneous quantification of protein–DNA interactions and transcriptomes in single cells with scDam&T-seq. Nature Protocols, 15(6), 1922–1953. https://doi.org/10.1038/s41596-020-0314-8 Rang, F. J., de Luca, K. L., de Vries, S. S., Valdes-Quezada, C., Boele, E., Nguyen, P. D., Guerreiro, I., Sato, Y., Kimura, H., Bakkers, J., & Kind, J. (2022). Single-cell profiling of transcriptome and histone modifications with EpiDamID. Molecular Cell, 82(10), 1956-1970.e14. https://doi.org/10.1016/j.molcel.2022.03.009   Related Episodes Dosage Compensation in Drosophila (Asifa Akhtar) Chromatin Profiling: From ChIP to CUT&RUN, CUT&Tag and CUTAC (Steven Henikoff) Single Cell Epigenomics in Neuronal Development (Tim Petros)   Contact Epigenetics Podcast on Twitter Epigenetics Podcast on Instagram Epigenetics Podcast on Mastodon Active Motif on Twitter Active Motif on LinkedIn Email: podcast@activemotif.com

Forschung Aktuell - Deutschlandfunk
Steinzeit: Forschende rekonstruieren uralte Bakterien-Genome

Forschung Aktuell - Deutschlandfunk

Play Episode Listen Later May 5, 2023 7:23


Böddeker, Michaelwww.deutschlandfunk.de, Forschung aktuellDirekter Link zur Audiodatei

New Scientist Weekly
#188 Consciousness measured at point of death; the lifeform with seven genomes; impact of Covid on the gut

New Scientist Weekly

Play Episode Listen Later May 4, 2023 21:32


From bright lights at the end of a tunnel, to hearing dead loved ones, there are many common sensations related to near death experiences. But what's going on in the brain to cause them? The team hears about a signal measured in the brains of people just before they died.Aliens may make contact with Earth as early as 2029. That's the theory at least. The team explains how some of NASA's deep space spacecraft could be used to beam back messages from distant planets.For the first time an organism has been discovered with seven entirely distinct genomes inside it. The team finds out about this record breaking cryptomonad alga.Covid-19 could be wreaking havoc on our gut microbiome, explaining why so many people experience gastrointestinal symptoms while infected. The team finds out how the disease is interacting with the gut, and whether there are any long term effects.Alpha male elephant seals with the largest harems die younger than those with fewer females. Listen to the sounds of their territorial grunts as the team finds out what's going on.On the pod are Rowan Hooper, Clare Wilson, Alexandra Thompson and Michael Le Page. To read about these subjects and much more, you can subscribe to New Scientist magazine at newscientist.com.Events and discount codes:newscientist.com/rewildingnewscientist.com/universeweekend Hosted on Acast. See acast.com/privacy for more information.

Real Science Exchange
2023 Tri-State Dairy Nutrition Conference Q&A - New Revelations in Transition Cow Nutrition

Real Science Exchange

Play Episode Listen Later May 2, 2023 58:17


Guests: Dr. Mike Van Amburgh (Cornell University), Dr. Jose Santos (University of Florida), Dr. Heather White (University of Wisconsin-Madison)Gathering together at the 2023 Tri-State Dairy Nutrition Conference for the Balchem Mini-Symposium “New Revelations in Transition Cow Nutrition” are speakers Dr. Mike Van Amburgh, Dr. Jose Santos and Dr. Heather White. The mini symposium featured topics such as better understanding essential versus required nutrients, choline research as a nutritional requirement and insights on gaining the next five pounds of milk. Dr. Van Amburgh of Cornell University led the discussion, summarizing his report on essential and required nutrients such as amino acids and choline. He mentioned when formulating diets for lactating cows, it's important to understand there are other nutrients that aren't necessarily essential but are required. 4:53Shifting the conversation, Dr. Van Amburgh said establishing an optimum value has now replaced nutrient requirements based on energy. Recent evidence indicates that feeding rumen protected choline (RPC) significantly improves milk production. In addition, supplementing choline shows an increase in low-density lipoproteins (VLDL) output from the liver.  7:21Highlighting her research in supplementing choline, Dr. White shared that studies show a 20 to 25% increase from cells and culture after incorporating the nutrient. She added choline also increased the tricarboxylic acid cycle (TCA) capacity, indicating a shift in nutrient incorporation. 11:45 As milk increases when infusing non-essential amino acids or even by using meta-analysis to supplement choline, how is glucose supply impacted? Dr. Santos, who focused his research on meta-analysis, said that even with the concurrent increase in dry matter intake, efficiency has still increased. He went on to say that studies from Wisconsin and Michigan highlight the basic understanding of a cow's variable ability to synthesis glucose differently with the ability to produce at least two kilograms more milk consistently. 21:30Within some of Dr. White's meta-analysis research, she mentioned mixing choline into the total mixed ration (TMR) allowed for the opportunity to analyze exact intake and also outcome production or energy corrected milk (ECM) fat. 34:08If cost isn't an issue, Dr. Santos mentioned that he's seen experiments feeding choline longer than 21 days postpartum and into 105 days at 12.9 grams. While no major benefit showed at that dosage amount, he added that other studies have shown benefits feeding choline longer and into mid lactation. 39:41Switching gears, Scott Sorrell, podcast host and director of global marketing for Balchem asked Dr. Santos about epigenetics and the effect choline has on behavioral changes. 44:59Sharing that epigenetics shifts genomes without changing sequences, Dr. Santos mentioned that through a two-by-two factorial experiment on choline, research indicates calf behaviors shifting and performance increasing. He went on to mention that history shows 30% of calves that were born from control dams and fed colostrum from control dams died from lipopolysaccharide challenges. 51:10Wrapping up the conversation, Dr. Zimmerman, podcast co-host and technical services manager for Balchem said that research speaks for itself. He stated that higher producing cows continue to prove choline as a required nutrient for transition cows. 55:50Please subscribe and share with your industry friends to bring more people to join us around the Real Science Exchange virtual pub table.  If you want one of our new Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll get a shirt in the mail to you.

Curiosity Daily
Genetic Fertility, CO2 Suck Up, 2 Dad Mice

Curiosity Daily

Play Episode Listen Later Apr 28, 2023 14:33


Today you'll learn about how our genes can predict how many kids we'll have, how scientists have created a new method of sucking up CO2 from the atmosphere, and how a baby mouse was born from two biologically male mice! Genetic Fertility“Genetic variants influencing human fertility identified - new research.” n.a. 2023.https://www.ox.ac.uk/news/2023-03-02-genetic-variants-influencing-human-fertility-identified-new-research“Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus.” By Mathieson, et al. 2023.https://www.nature.com/articles/s41562-023-01528-6“The challenge of detecting recent natural selection in human populations.” by Mills & Mathieson. 2022.https://www.pnas.org/doi/10.1073/pnas.2203237119CO2 Suck Up“Climate change: New idea for sucking up CO2 from air shows promise.” By Matt McGrath. 2023.https://www.bbc.com/news/science-environment-64886116“Carbon capture: What is it and how does it fight climate change?” by Jonah Fisher. 2023.https://www.bbc.com/news/science-environment-64723497“Direct air capture (DAC) and sequestration of CO2: Dramatic effect of coordinated Cu(ll) onto a chelating weak base ion exchanger.” by Hao Chen, et al. 2023.https://www.science.org/doi/10.1126/sciadv.adg1956“How much is a ton of carbon dioxide?” by Kathryn Tso. 2020.https://climate.mit.edu/ask-mit/how-much-ton-carbon-dioxide2 Dad Mice“The mice with two dads: scientists create eggs from male cells” by Heidi Ledford & Max Kozlovhttps://www.nature.com/articles/d41586-023-00717-7“Healthy mice from same-sex parents have their own pups” by Jeremy Rehmhttps://www.nature.com/articles/d41586-018-0699Follow Curiosity Daily on your favorite podcast app to get smarter with Calli and Nate — for free! Still curious? Get exclusive science shows, nature documentaries, and more real-life entertainment on discovery+! Go to https://discoveryplus.com/curiosity to start your 7-day free trial. discovery+ is currently only available for US subscribers.Find episode transcripts here:https://curiosity-daily-4e53644e.simplecast.com/episodes/genetic-fertility-co2-suck-up-2-dad-mice

Inspire Someone Today
E84 | Anu Acharya | World of Genomics

Inspire Someone Today

Play Episode Play 30 sec Highlight Listen Later Apr 27, 2023 57:31


Anu Acharya is a serial entrepreneur, columnist, poet, and charismatic speaker. As the Founder & CEO of Mapmygenome, she introduced the concept of personal genomics in India with the launch of Genomepatri in 2013. She co-founded and pioneered her first venture Ocimum Biosolutions from 2000 to 2013 through innovative bioinformatics and LIMS solutions, global acquisitions, awards, and fundraises.Awards and Honours: Honoured with ‘She is': 75 Women in STEAM(fields of Science, Technology, Engineering, Arts, and Maths); WTI Award (Niti Aayog); Woman Entrepreneur of the Year Award (Indian Express)(2022); Woman Entrepreneur of the Year Award (Zee Business), Special Recognition (Leaders Category) by Indian Express; Pride of Telangana Award (2018); IIT Kharagpur Distinguished Alumnus Award; Young Leaders Forum of British High Commission; Young Global Leader of World Economic Forum Class of 2011;She serves on governing boards of NIBMG; IIIT Hyderabad and WeHub; Advisory board at Action For India & KIIT; Board of mentors for Ivy Cap Ventures; a member of CII National Committee on Biotechnology; Committee Member of HIMSS Asia Pacific India Chapter; NASSCOM Executive Council Member.TimestampsThe early life and Career of Anu Acharya - 2:30Multiple facets of Anu - 12:40Definiton of success - 17:16Understanding Genomics - 28:07Power of 3 - 37:10Map my Genome and understand the markers - 45:45Making it Stick - 51:21IST Message - 56:10QuotesHave the freedom to make your own choiceYour environment determines who you becomeSuccess is the difference between what you expect and what you achievePrevention is not better than cure; prevention is the cureA big element of any business is people and customersBetter awareness leads to better actionsConnect with Anu Acharya:  LinkedIn | Website |TwitterDo not miss to check out our new website and share your love https://inspiresomeonetoday.in/Do stay tuned for new episodes every alternate Friday. Next episode -May 12 ‘23. Available on all podcast platforms, including, Google Podcasts, Apple Podcasts, YouTube, Spotify

Cendrine's Podcast
101 | The oversoul network & activating our crystalline divine genome

Cendrine's Podcast

Play Episode Listen Later Apr 26, 2023 19:18


In this transmission, learn about the architecture of the oversoul network, how to embody its algorithm and the activation of our crystalline divine genome.  After this transmission, you will have a much deeper understanding of this amazing engineering that each of us has and how we can use it to access more of our soul gifts and talents to accelerate our ascension and embrace the unified field, particularly during April. Are we part of alternate realities? Do we have parallel lives? What inter-dimensional connections do we have? What is the purpose of our life in this incarnation? Is my crystalline divine genome activated? All of these questions and more will be answered! This episode covers: The oversoul network The descent of the soul & DNA The crystalline divine genome The unified field How to access DNA upgrades Useful links:  Meditation for oversoul network Free - https://cendrines.kartra.com/page/freesoulblueprintmeditation Crystalline DNA trance channelled activation -$19 https://cendrines.kartra.com/page/crystallinedna

Genetics Unzipped
S6.08: Pop goes the genome! Genetics in popular culture

Genetics Unzipped

Play Episode Listen Later Apr 20, 2023 34:16


We take a leftfield look at public communication of genetics, exploring how the science of DNA turns up in popular culture from comics and music to cakes, with Great British Bake Off winner Syabira Yusoff.Full show notes, transcript and references online at GeneticsUnzipped.com Follow us on Twitter @GeneticsUnzipThis episode of Genetics Unzipped was written and presented by Kat Arney with audio production by Emma Werner and Sally Le Page.This podcast is produced by First Create the Media for the Genetics Society - one of the oldest learned societies dedicated to promoting research, training, teaching and public engagement in all areas of genetics.

Creation Moments on Oneplace.com
Fly Genome Puzzles Evolutionary Scientists

Creation Moments on Oneplace.com

Play Episode Listen Later Apr 13, 2023 2:00


Psalm 119:73 Thy hands have made me and fashioned me: give me understanding, that I may learn thy commandments. To support this ministry financially, visit: https://www.oneplace.com/donate/1232/29

Fitness Confidential with Vinnie Tortorich
Best Of: Sugar Fuels Cancer with Dr. Thomas Seyfreid - Episode 2317

Fitness Confidential with Vinnie Tortorich

Play Episode Listen Later Apr 12, 2023 60:20


Episode 2317 - BEST OF: Today we replay an episode from 2015 when Vinnie Tortorich welcomes Dr. Thomas Seyfried from Boston College and they discuss all about how sugar fuels cancer. https:/vinnietortorich.com/2024/04/best-of-sugar-fuels-cancer-dr-thomas-seyfreid-episode-2317 PLEASE SUPPORT OUR SPONSORS SUGAR FUELS CANCER After leukemia (and during) people kept telling Vinnie he needed to do certain things. (3:00) Eat macro-diet and micro-diet, juice everything, have wheatgrass, etc. or he would die. He went to his hematologist and asked how much of it was the truth. His incredibly intelligent hematologist simply said, "Stay away from sugar!" Everything is pointing toward sugar as one of the things that cancer loves. Sugar does not cause cancer, but cells that make tumors feed on sugar. (4:40) Sugar is a prime fuel, but not the only fuel. Our red blood cells are constantly making a little lactate. Tumor cells have defective mitochondria so they make lots of lactate. Dr. Seyfreid explains the mechanisms behind the process and why it's so important to understand. WHAT CAUSES CANCER? Cancer can be caused by a variety of things. (8:20) Some examples are radiation exposure, chemicals in the environment, chronic inflammation, and age. Mutations in genomes that we inherit can be involved. (10:35) People can be predisposed to cancers. Genomes are your set of genes and differences and mutations in them. However, there is a misunderstanding about cancer; the industry has believed that cancer is genetic because tumors have mutations. (11:50) This has caused a lot of misdirection in research and treatment. Dr. Seyfried explains even more of the science of how cancer cells work; cancer is a metabolic disease. (23:30) They also discuss the benefits of ketones and the ketogenic diet. It is highly important to understand the difference between ketosis and ketoacidosis--they are very different things. They discuss therapeutic ketones and whether or not they can help certain brain processing issues like autism. (55:00) You can read more about Dr. Seyfreid on Boston College's website. Dr. Seyfreid recommends the book , by Travis Christofferson.

I AM BIO
The New Age of CRISPR

I AM BIO

Play Episode Listen Later Apr 11, 2023 27:40


CRISPR has emerged as a powerful tool for altering DNA sequences with incredible precision, opening up new avenues of research into the treatment of disease. In this episode, we explore the science behind CRISPR, as well as its potential. From curing genetic disorders to creating new crop varieties, the possibilities seem endless. Our four guests today are scientists working to push these gene editing tools to the next frontier.

The Scientist Speaks
Genomes Across the Tree of Life

The Scientist Speaks

Play Episode Listen Later Mar 30, 2023 24:10


Scientists often refer to DNA as the blueprint of a cell. Whether the genetic material is single stranded or double stranded, linear or circular, organisms across the tree of life rely on their genomic blueprint for instructions on living, growing, and reproducing. Due to the amount of information carried by this blueprint, the size of the genome poses a biological dilemma; from humans to single-celled aquatic organisms, all eukaryotes must find a solution for organizing their DNA into a tiny nuclear space. In the quest for better tools to understand the 3D genomic architecture and the biological challenge of chromosome folding, a team of biochemistry and systems biology researchers investigated the unique genomic organization of unicellular marine plankton, dinoflagellates. In this episode, Deanna MacNeil from The Scientist's Creative Services Team spoke with Job Dekker, a systems biology professor at the University of Massachusetts Chan Medical School and an investigator at the Howard Hughes Medical Institute, to learn more.   The Scientist Speaks is a podcast produced by The Scientist's Creative Services Team. Our podcast is by scientists and for scientists. Once a month, we bring you the stories behind news-worthy molecular biology research. This month's episode is sponsored by Arima Genomics.

Trends from the Trenches
Episode: 16 - Kjiersten Fagnan on the JGI's Genome Citation Service That Tracks Genomes Across Research

Trends from the Trenches

Play Episode Listen Later Mar 28, 2023 25:17


Kjiersten Fagnan is an applied mathematician enamored of biology's messy datasets. Now, as chief informatics officer at the Department of Energy Joint Genome Institute (JGI), located at Lawrence Berkeley National Laboratory, she finds bioinformatics' computational and data challenges very different from applied math or partial differential equations. Fagnan is the newest guest on the Trends from the Trenches podcast, speaking with host Stan Gloss of BioTeam about JGI's Genome Citation Service, a new offering that connects the broader community with the organization's massive data resources and infrastructure. Fagnan talks about the centralized data management system JGI deployed 10 years ago in response to exponential data growth and the questions it forced the organization to ask about the quality and utility of the data it produces and manages. “One of our goals is to see… the impact of the data generated amplified through reuse of the data,” she says. Fagnan also discusses JGI's strategic collaboration with NamesforLife to create a unique global identifier to help researchers link work on the same microbe even as naming conventions change over time. Additionally, she talks about why perfection is the enemy of reality and JGI's immediate and long-term plans for the Genome Citation Service. Links from this episode:  Bio-IT World BioTeam Department of Energy Joint Genome Institute 2023 Bio-IT World Conference & Expo Kjiersten Fagnan's direct email The Role of Data Management in Advancing Biology JGI's Integrated Microbial Genomes & Microbiomes (IMG/M) system JGI's Genomes OnLine Database Trends from the Trenches boiler: Bio-IT World's Trends from the Trenches podcast delivers your insider's look at the science, technology, and executive trends driving the life sciences through conversations with industry leaders. BioTeam co-founder Stan Gloss brings years of industry experience in science, data, and technology to conversations exploring what is driving data and discovery, and what's coming next.

Mendelspod Podcast
Nevermind the $200 Genome, Element CEO Molly He Says Core Chemistry Capable of Much More

Mendelspod Podcast

Play Episode Listen Later Mar 23, 2023


"We're not a sequencing company," says Molly He, CEO and co-founder of Element Biosciences in our first interview with the leader of the hot new sequencing company which seemed to come out of nowhere this past year. “We're a biology company.” Not a sequencing company? Element has just taken the lead in the race toward cheap clinical genomes, and their CEO is putting that news aside in today's interview. Instead, she's much more interested in touting the company's core technology “avidity.” The term comes from a core reagent the company has labeled an “avidite.”

Intelligent Design the Future
Richard Sternberg on the Trail of the Immaterial Genome

Intelligent Design the Future

Play Episode Listen Later Mar 10, 2023 22:58 Very Popular


Dr. Richard Sternberg speaks on his mathematical/logical work showing the difficulty of identifying genes purely with material phenomena. Source

Intelligent Design the Future
Chimp and Human Genomes: An Evolution Myth Unravels

Intelligent Design the Future

Play Episode Listen Later Feb 20, 2023 29:46


On today's ID the Future, Casey Luskin rebuts the oft-repeated claim that the human and chimp genomes are 98-99% similar and therefore surely resulted from Darwinian common descent. Luskin cites an article in the journal Science which describes the 98-99% claim as a myth. The original figure was derived from a single protein-to-protein comparison, but once you compare the entire genomes, and use more rigorous methods, the similarity drops several percentage points, and on one account, down into the mid-80s. Additionally, the chimp genomes used in the original comparison studies borrowed the human genome for scaffolding, thus artificially boosting the degree of similarity. What about supposed junk DNA similarities between human and chimp? Why would an intelligent designer put the Read More › Source