Podcasts about lymphocytes

1er épisode / 5, de la série sur les encéphalites auto-immunes. Episode 1 : Maladie rare – Qu'appelle-t-on Encéphalite auto-immune ? Invité : Pr Jérôme Honnorat, neurologue, chef du service de neuro-oncologie à l'hôpital neurologique Pierre-Wertheimer des Hospices Civils de Lyon, coordonnateur du récent PNDS sur les encéphalites à anticorps anti-NMDAR, responsable de l'équipe de recherche SynatAc, INSERM et CNRS, au sein de l'Institut MeLiS, et médecin coordonnateur du centre de référence des syndromes neurologiques paranéoplasiques et encéphalites auto-immunes affilié à la filière Brain-Team. https://inmg.fr/melis/fr/index.php  https://www.chu-lyon.fr/centre-de-reference-des-syndromes-neurologiques-paraneoplasiques-et-encephalites-auto-immunes  https://brain-team.fr/    1️⃣   Qu'appelle-t-on encéphalite auto-immune ? [0'46 – 3'54] ✔️ Maladie rare où le système immunitaire attaque le système nerveux central. ✔️ Provoque troubles de mémoire, crises d'épilepsie et parfois coma. ✔️ Diagnostic complexe, basé sur la détection d'autoanticorps. Pour plus d'informations, retrouvez notre page article : https://rarealecoute.com/encephalite-auto-immune/ 2️⃣   Quelle est la physiopathologie de cette maladie rare ? [3'55 – 6'35] ✔️ Production d'autoanticorps attaquant des protéines neuronales, entraînant une atteinte du système nerveux. ✔️ Elle peut être liée à des cancers (syndromes paranéoplasiques) ou idiopathique. 3️⃣   Quel est le pronostic de l'encéphalite auto-immune ? [6'36 -7'30] ✔️ Le pronostic dépend de l'anticorps impliqué et/ou de la présence d'une tumeur initiale ; ✔️ Si l'autoanticorps cible une protéine membranaire, un traitement adapté peut permettre une récupération complète ; ✔️En cas de destruction neuronale, la rééducation aide, mais la récupération est plus limitée, d'où l'importance d'un diagnostic précoce. 4️⃣   À qui adresser les patients en cas de suspicion d'encéphalite auto-immune ? [7'31 – 8'27] ✔️ Adressage aux centres de références / compétences affiliés à la filière Brain-Team. ✔️ Prélèvements à analyser dans un laboratoire de référence.   L'équipe : Virginie Druenne – Ambassadrice RARE à l'écoute Cyril Cassard – Journaliste/Animation Hervé Guillot - Production Crédits : Sonacom *************************************************** À propos : "RARE à l'écoute" est un podcast dédié à la sensibilisation aux maladies rares et au soutien des personnes touchées par ces affections. Créé par un groupe passionné de professionnels de la santé, le podcast vise à informer les professionnels de santé et fournissant des informations sur les dernières avancées médicales et scientifiques dans le domaine des maladies rares, et inspirer les patients et leurs proches en partageant des histoires de courage et de persévérance. Contenu :

Hello Friend, Have you ever been told, “Your blood tests are normal,” but deep down you know something isn't right? It's one of the most frustrating things to hear, especially when you're dealing with fatigue, brain fog, or other unexplained symptoms. Here's the truth: those “normal” lab results might still hold valuable clues about your health—if you know where to look. Your CBC panel, a test you've probably already had done, includes five key markers that can reveal so much about what's really going on inside your body. In this week's episode of Functional Medicine for Christian Women, I break down the CBC differential and explain how Neutrophils, Lymphocytes, Eosinophils, Basophils, and Monocytes can provide insight into your immune function, inflammation, and even chronic stress. I'll show you why this simple test is often the best starting place for uncovering the root cause of your symptoms—and how you can use it to take the first step toward feeling better. In health, Lacy Lain, FMCHC, LEHP P.S. If you've ever felt dismissed by conventional doctors, I made this episode with you in mind. Let's start finding the answers your body is trying to tell you. What's Next? Book Your Free Consultation: Sick Of Feeling Like Junk, Know Something's Not Right, Yet You're Told By Your Doctors That Your Labs Are “Normal”... Connect with Lacy: Apply to work with Lacy 1:1 (two spots now open!) The Stronger Collective App Learn more by clicking here. Related Episodes You Might Enjoy: 42. Why Am I Always Tired? Common Causes of Chronic Fatigue in Working Women 27. Why Career-Driven Women Should Care About Blue Zones, Air Quality, and Houseplants for Better Indoor Air 45. Unlock Your Energy: How Hormones Could Be the Key to Fixing Your Fatigue 33. Bandaid Solutions vs Functional Solutions in Women's Health 47. How NAD+ Can Help Exhausted Women Regain Their Energy Naturally - Disclaimer: Our life and health coaches do not diagnose, treat, prevent, or cure any disease or condition. Nothing we share with our clients is intended to substitute for the advice, treatment, or diagnosis of a qualified licensed physician. Lacy Lain, FMCHC may not make any medical diagnoses or claim, nor substitute for your personal physician's care. It is the role of Lacy Lain and her Practitioners to partner with their clients to provide ongoing support and accountability in an opt-in model of self-care and should be done under the supervision of a licensed physician. These platforms share personal experiences and provides education. Interaction on these platforms does not constitute a doctor/patient relationship.

Dr. Gail Bishop is a Professor of Microbiology and Immunology at the University of Iowa, where her lab studies the molecular mechanisms underlying lymphocyte activation and tolerance.  She talks about TRAF signaling, the NFκB pathway, and effects on B and T lymphocytes. She also discusses her role as Editor-in-Chief of The Journal of Immunology.

View the Show Notes For This Episode Dr. James Lavalle discusses Metaflammaging with Dr. Ben Weitz. [If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.] Podcast Highlights In this episode of the Rational Wellness Podcast, host Dr. Ben Weitz engages in a comprehensive discussion with Dr. James LaValle, an internationally recognized clinical pharmacist and nutritionist. They delve into the concept of metaflammation—metabolic inflammation—and its impact on health and aging. Dr. LaValle shares his personal journey into integrative and functional medicine, his work with athletes and professional teams, and his development of the Metabolic Code. He also discusses the significance of various biomarkers for assessing health, the role of GLP-1 agonists in obesity and diabetes management, and the potential benefits and concerns surrounding peptides. Additionally, they cover the importance of lifestyle changes, stress management, and innovative health technologies in promoting longevity and well-being.   00:00 Introduction to the Rational Wellness Podcast 00:29 Meet Dr. James LaValle: A Journey in Integrative Medicine 05:26 The Metabolic Code and Personalized Care 06:33 The Role of Lifetime in Promoting Wellness 07:31 Understanding Biomarkers and Metabolic Health 18:02 The Impact of GLP-1s and Lifestyle Changes 27:12 Concerns and Considerations with GLP-1s 31:05 Inflammation Markers: Mean Platelet Volume and Neutrophil Lymphocyte Ratio 31:42 Understanding Metabolic Inflammation 32:09 The Role of Basophils and Cortisol in Inflammation 32:25 Neutrophils, Lymphocytes, and Immune System Stress 33:27 Monocytes and Macrophages: Indicators of Inflammation 36:12 The Importance of Urinary pH and Kidney Health 37:47 Root Causes of Obesity: Genetics, Environment, and Nutrient Deficiencies 39:14 The Impact of Prescription Drugs on Weight Gain 39:49 Magnesium Deficiency and Metabolic Syndrome 40:54 The Problem with Ultra-Processed Foods 42:36 The Importance of Personal Health Responsibility 44:11 Exploring Peptides and Their Benefits 48:54 Innovations in Longevity and Health Supplements 54:22 The Science Behind Synapsin and RG3 58:45 Conclusion and Final Thoughts   Dr. James Lavalle is an internationally recognized clinical pharmacist and a board certified clinical nutritionist for close to 40 years and he is the author of more than 20 books including, “Cracking the Metabolic Code.”  He has lectured for more than a decade for the American Academy of Anti-Aging Medicine.   Jim has served thousands of patients using his "Metabolic Model for Health" through his integrative health practice, LaValle Metabolix in Orange County, CA.   James is best known for his expertise in personalized integrative therapies uncovering the underlying metabolic issues that keep people from feeling healthy and vital.  His website is JimLavalle.com.  To find out more about his nutrition products that he has developed, including Synapsin, please go to MetabolicElite.co.   Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure.  Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

Tumor infiltrating lymphocyte (TIL) therapy uses a person's own immune cells to fight advanced melanoma, offering new hope for patients who have limited treatment options. This week, we have a conversation with Brian Gastman, EVP of medical affairs at Iovance Biotherapeutics, about TILs and the company's pipeline.Iovance recently submitted a marketing authorization application to the European Medicines Agency for lifileucel, a TIL cell therapy, for the treatment of adult patients with unresectable or metastatic melanoma previously treated with a PD-1 blocking antibody, and if BRAF V600 mutation positive, a BRAF inhibitor with or without a MEK inhibitor. If approved, lifileucel will be the first and only approved therapy in this treatment setting in all European Union member states.The submission is supported by positive clinical data from the C-144-01 clinical trial in patients with advanced post-anti-PD1 melanoma.Iovance's Amtagvi is the first FDA-approved T cell therapy for a solid tumor indication. 00:47-04:44: About Iovance Biotherapeutics04:44-07:57: What is polyclonal tumor infiltrating lymphocyte treatment?07:57-14:55: What is the production process for TILs?14:55-18:32: Are there any limiting factors for TIL treatment?18:32-20:59: Is early intervention important?20:59-21:22: Does better psychology help?21:22-22:06: Are other companies working on TILs?22:06-27:25: Clinical trials 27:25-29:25: How do you address cost?29:25-34:21: Iovance's pipeline34:21-35:30: Can TILs be improved?35:30-37:21: Where does the TIL space go from here?Interested in being a sponsor of an episode of our podcast? Discover how you can get involved here! Stay updated by subscribing to our newsletter

Join Professor Iain McInnes and Professors Hideto Kameda and Peter Nash for the latest episode on The Immune-Mediated Inflammatory Disease Forum, where they discuss the latest information and data in RA. In this episode, they discuss a paper that investigated whether the baseline neutrophil-to-lymphocyte ratio had an effect on the treatment response to filgotinib.

References Neuromolecular Medicine. 2018. Jun. 20(2): 1559-1174 Cell Rep. 2018 Feb 6; 22(6): 1509–1521 Cell Cycle .2008.7(15):2296-8 Front. Immunol., 18 June 2013 Sec. T Cell Biology Tchaikovsky, PI. 1874. Piano Concerto 1. B Minor. Opus 23. https://youtu.be/W6Zr_0LYYTI?si=YlrIK-UDVGHbMp4P --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

In this week's episode we'll discuss the safety and efficacy of decitabine in older patients with AML; learn how heme-induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice, and discuss the outcomes of treatment with HLA-mismatched HSCT with TCRab/CD19 lymphocyte depletion or post-HSCT cyclophosphamide for inborn errors of immunity. Featured Articles:Decitabine in older patients with AML: Quality of life results of the EORTC-GIMEMA-GMDS-SG randomized phase III trial Heme induced loss of renovascular endothelial protein C receptor promotes chronic kidney disease in sickle mice Outcomes of HLA-mismatched HSCT with TCRab/CD19 depletion or post-HSCT cyclophosphamide for inborn errors or immunity 

References J Pineal Res. 2017;62:e12391 PLoS One. 2015; 10(9): e0137193 Aging. IntechOpen. (2024). Sirtuins and Melatonin: Linking Chronobiology to Inflammation and Aging. doi: 10.5772/intechopen.1003914 Blood Cancer J. 2024 Dec; 14(1): 24 The Byrds (multiple artists). 1968. ""Sweetheart of the Rodeo". (Lp). https://youtu.be/zxzV5XoLpto?si=OFb3eHDb2ghdz16V Ravel, M. 1928. "Bolero" . M 81. https://youtu.be/E9PiL5icwic?si=a9rYVLbBexOhR0M4 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Cells 2020, 9(1), 228 Front. Immunol. 2020. vol 11. 29 November. FEBS 2013. Volume280, Issue15 August:3530-3541 Cell Metabolism 2016. 23, 1127–1139 Beethoven. LV . 1800. Septett Es-Dur op. 20 https://youtu.be/pXsj43qCcUA?si=r5vW4PpfzvywF9b3  Jacques Revaux  Gilles Thibaut and Claude François 1967. "My Way". Sinatra https://youtu.be/qQzdAsjWGPg?si=YWKurvGp9Xt0TYK1 --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Circ Res. 2018 Sep 14; 123(7):868–885. IntechOpen. 2024. doi: 10.5772/intechopen.1003914 Intl Myeloma Foundation 2024. Clin Biochem Rev. 2009 Aug; 30(3): 105–111. Br J Pharmacol. 2018. Aug; 175(16): 3251–3262 Int J Mol Sci. 2020. Nov; 21(22): 8609 Telemann, G.P. 1733. Tafelmusik https://youtu.be/VTP9evStK64?si=3m_Mw3B7IFo0i_el --- Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Nucleic Acids Res. 2022 Jan 7; 50(D1): D413–D420 Cancers (Basel). 2019 May; 11(5): 678 Oncogene 2017. volume 36: 5593–5608 NAR Cancer. 2024 Jun; 6(2): zcae023. Cell. 2021 Apr 1; 184(7):1790–1803.e17 Nature Immunology 2018. volume 19: 871–884 Pisendel, JG. 1735. Violin Concerto in D major, https://youtu.be/eRVueayvMIk?si=Nitfg70Kwdmo7Xt7 Hayward, J. 1969. "Never Comes the Day" et al. from [Threshold of a Dream] lp. https://youtu.be/W8BNMfyoxgs?si=n9QH7_j_T7ZC7pnx --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References MAbs. 2022; 14(1): 2107971 Commun Biol. 2022; 5: 1292 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Guerra, DJ. 2024. ImmunoBiochemistry lectures. Commun Biol. 2022; 5: 1292. ACS Chem. Biol. 2017, 12, 4, 958–968 Telemann, GP., 1750. Sonata in D major, TWV 44:1 https://youtu.be/xx8ooc-s7OQ?si=1vAKmdcLroNISa-P Vivaldi, A., 1708. - Gloria (RV 589) https://youtu.be/2eWjQOdYzMQ?si=hYSOqRuXkYUA8ATl --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Immunotherapy and cellular therapeutics represent the future of cancer care. These biological therapies involve manipulating the body's cells to reactivate and strengthen their abilities to attack cancer cells. Immunotherapy is a precision cancer treatment and is considered the future of cancer treatment by the National Cancer Institute. Other, more traditional, types of cancer treatment include surgery, chemotherapy and radiation. Immunotherapy is a type of treatment for a variety of cancers that harnesses one's own immune system to fight his or her specific cancer cells. Tumor infiltrating lymphocyte, or TIL therapy, is a type of immunotherapy and part of the body's natural response to cancer. TIL cells are naturally occurring immune cells that are on constant surveillance to recognize, attack and kill cancer cells. Recently, the Food and Drug Administration approved lifileucel (Amtagvi), the first treatment for cancer that uses TILs. On this episode, Dr. Roy Jensen, vice chancellor and director of KU Cancer Center speaks with Dr. Muhammad Mushtaq, associate professor of hematologic malignancies and cellular therapeutics at the University of Kansas Medical Center, about this exciting topic. Links from this Episode: Learn more about TIL therapy via the National Cancer Institute Read the frequently asked questions about immunotherapy on the KU Cancer Center website Learn about Dr. Mushtaq Read the FDA's announcement of approval for TIL therapy Learn more about cancer clinical trials at KU Cancer Center After listening to this episode, we invite YOU to be a part of the podcast! We want to hear your thoughts on the conversations we have here, topics you'd like to learn more about and any questions you may have for our guests. Call our Bench to Bedside hotline at 913-588-3880 and leave us a voicemail, or you can email your comments and questions to benchtobedside@kumc.edu. Your comments may be shared on a future episode!

References Trends in Immunology. 2017. REVIEW| VOLUME 38, ISSUE 4, P287-297. FASEB J. 2020 May;34(5):6185-6197. Couperin, F. 1714. Troisième Leçon De Ténèbres À 2 Voix https://youtu.be/UbREakKFTow?si=JqmA1GQQpTOItUSg Lennon-McCartney. 1970. "Let it Be" https://youtu.be/QDYfEBY9NM4?si=nH4LJs4gprJVvcR1 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Nutrition. 2021-11-01, Volume 91, Article 111388 Front Immunol. 2022 Jan 5:12:806529. Cells. 2019 Aug; 8(8): 939. Lennon-McCartney 1963."She Loves You" [Beatles Second Album; lp] https://youtu.be/oVCwDl-S09A?si=ZjD89e5pwvXf5864 Schmelzer, JH, 1664 " Violin Sonata, in A Minor. 'Cucù'" https://youtu.be/x1TsJFeB2x8?si=JiqwHG2GcOf2ddeT --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Int J Mol Sci. 2019 Oct; 20(20): 5028 Nutrition. 2021-11-01, Volume 91, Article 111388 Bach, JS. 1720. "Brandenburg Concerto No. 6" in B Flat Major. BMV. 1051. https://youtu.be/_tr_uYEQkrs?si=rXXWMBAnWGbEuAOk Hunter-Garcia. 1970. "Stella Blue". [Wake of the Flood;lp] https://youtu.be/VKsWDyvWaL4?si=DnHgzSEiiKeUOXbj --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Int J Mol Sci. 2019 Oct; 20(20): 5028. Lennon-McCartney. 1964. "Ill Be Back" https://youtu.be/fJSTBNTac6k?si=rr4rWE86TIs8EZcL Bruch, M. 1866. Violin Concerto 1. G minor https://youtu.be/9BeV9XDs64w?si=AvEAQch7T8TJrt05 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Circulation. 2023.Oct 17;148(16):1231-1249. Int J Mol Sci . 2019. Oct 11;20(20):5028. Front Immunol. 2019; 10: 1706 Mastin, T. 1967 "How do you Feel" [Jefferson Airplane]. Surrealistic Pillow.lp. https://youtu.be/iWUa-rKT-oY?si=1M9496MbDUBGuj0A Hunter, Garcia, Kreutzman. 1975. "Franklin's Tower" [ Grateful Dead. Blues for Alah].lp. https://youtu.be/55TOIJxKc74?si=2wiiTKbWjw5LQvxF Haydn, FJ. 1790. String Quartet in D Major, Op. 64 No. 5 https://youtu.be/vNN_Kbuf7_U?si=KSfUc226hIIAmcy- --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

When you visit your doctor for a routine physical, the protocol often includes ordering blood work. Why? What can the results indicate?Your doctor looks at your lab results to help diagnose and monitor treatment for many conditions. However, many patients, probably even you, have experienced being told that their labs are normal, but they feel awful. What if you could read your blood work and determine what's going on inside your body? Today, I'll walk you through reading blood work, but instead of looking at the normal ranges, we will look at the functional ranges and understand what the numbers mean. Specifically, we will look at the five markers inside your CBC with differential. This episode is the first part of a 3-hour Blood Work and Business Intensive session. Watch out for Parts 2 and 3.Have you ever wished you had a step-by-step process to create a treatment plan for any client seeking your help? One you felt confident with and only needed their regular blood work to create? That's what we are doing during the one-day event: Functional Medicine Made Easy. Get the details and register at drkylieburton.com/fm"Today's episode is brought to you by StarWalker Organic Farms. We're a third-generation family-run farm deeply committed to producing the highest quality organic beef, pork, and artisanal jerky. With a strong belief in the power of regenerative farming, we aim to produce not only richer, more nutritious products but also to nurture the land for generations to come. Our dedication to organic and humane practices means every cut of meat supports wellness, the environment, and the well-being of our animals. And the best part? We ship nationwide, bringing the StarWalker difference directly to your door. Elevate your health with sustainably sourced meats. Visit us at starwalkerorganicfarms.com to discover more."My favorite place for ordering labs is virtualclinic.MD. Make your account and order functional medicine labs and regular blood work at any Labcorp facility across the country. Yes, you can order labs as a health coach through this platform. As long as you have a healthcare business, you can order labs. Make your account and start ordering today - tell them Dr. Kylie Burton sent you.Leave a review, share it with your colleagues, and let people on social media know you love what you're hearing. Spread the message, and I'll be very grateful for it!“We're not reading the labs to diagnose. We're reading them to figure out what the heck is wrong with our patient.”- Dr. Kylie Burton In This Episode:Do you need a license to read blood work?What is the purpose of reading a patient's blood work?Normal range vs. Functional rangeThe CBC with differentialWBC and what the range meanWhat does the Neutrophil count indicate?What does the Lymphocyte count indicate?What does the Monocyte count indicate?What do the Eosinophil and Basophil ranges indicate?WBC breakdown and what the numbers mean Practical application (let's read some blood work)Resources:Build Your Virtual Platform in 90 Days - https://drkylieburton.com/business/Join the 90-day...

References Guerra, D. 2023-24 lipid lectures J Oleo Sci. 2011; 60(10): 537–544. Gregorian Chants: 1100 AD. Beata es Virgo Maria https://youtu.be/rMlWhAh2Zvc?si=B3XqzCsQYef_ee6t Schubert, F. 1822. Schubert | Mass No. 5 in A flat major D 678 https://youtu.be/Yl5YF3PeUeI?si=AP9U_WHULnv3ItWi --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References J Am Soc Mass Spectrom. 2023 Nov 1;34(11):2481-2490 J Oleo Sci. 2011; 60(10): 537–544. Trends Immunol. 2018 Jul; 39(7): 523–535. Blood. 2014 Dec 4; 124(24): 3656–3665. George, L. and B. Payne. 1970. "Truck Stop Girl". Byrds. [Untitled] lp. https://youtu.be/fdI83TNKdX4?si=JWPrSMCHEX5G1zi9 Georgia Dobbins, William Garrett, Freddie Gorman, Brian Holland, Robert Bateman. 1961. "Mr. Postman". The Beatles. [With the Beatles ] lp. https://youtu.be/v2Kk5IG2b8E?si=xcG0eUV54Bpo_T9H Bach JS. ca. 1720. Violin Concerto No.1 in a minor BWV1041 https://youtu.be/Q3-5144TaYg?si=K9eYagdfdykygw9d --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Dev Cell. 2016 Jul 25; 38(2): 161–169. J Biol Chem. 2010 Jul 16; 285(29): 22328–22337 Landes Bioscience; 2000-2013.Madame Curie Bioscience Database [Internet]. https://www.ncbi.nlm.nih.gov/books/NBK6207/ Nat Med. 2003 Aug;9(8):1020-5 National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 107970, Fingolimod. Retrieved April 20, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Fingolimod. Chopin, F. 1830. Piano Concerto No. 1 in E minor, Op. 11 https://youtu.be/rsOp47o2doM?si=1yD6x1KnMmXMR23X Hunter-Garcia. 1969. "St Stephen" [performed by Grateful Dead] Live Dead lp.(1969) https://youtu.be/xZ5TftMTPOE?si=6nUc6EiBqRPEduFr --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Proc Natl Acad Sci U S A. 2015 Jul 14; 112(28): 8661–8666 J Exp Med. 2021 Nov 1; 218(11): e20210417 J Biol Chem. 2010 Jul 16; 285(29): 22328–22337. Brahms. J. 1879. Violin Concerto D. Major. OP 77. https://youtu.be/9L6a-JJCCzw?si=r7IAjxBC8ZBfDOaR McCartney/Lennon.1967. "She's Leaving Home" on [Beatles] SPLHCB lp. https://youtu.be/VaBPY78D88g?si=n2R4CQF6tm8TuM9h --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Cold Spring Harb Perspect Med. 2020 Jun; 10(6): a034819 Proc Natl Acad Sci U S A. 2015 Jul 14; 112(28): 8661–8666 Blood. 2010 Jul 22; 116(3): 485–494. Haydn, FJ. 1793. Symphony No 101 D major "Die Uhr“. https://youtu.be/jK9EPZ3qdgU?si=GiCVxNOchDW0fKsb Croce, J. 1970. "Time in a Bottle". https://youtu.be/9h1davKgBYM?si=YhyPwAtno04oYBks --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Front. Immunol., 2022 Sec. Microbial Immunology Volume 12 Blood 2010. Volume 115, Issue 18, 6 May: 3708-3717 Seeger, P. 1959 . Performed by The Byrds "Turn Turn Turn" https://youtu.be/W4ga_M5Zdn4?si=ODKk_snS-5XHZvWP Copland, A. 1944. "Appalachian Spring. https://youtu.be/CJYVH_kZkOk?si=UUBet58ETg0PVUrB --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References FEBS J. 2018 Aug; 285(16): 2944–2971. Nature Reviews Immunology 2023. volume 23, pages 236–250. Angiogenesis. 2021; 24(4): 719–753. Front. Immunol. 2022 Sec. Microbial Immunology Volume 12 Camp, H. 1964. "Pride of Man". performed by Quicksilver Messenger Service. https://youtu.be/fG6A6G9uzsQ?si=tKMdQMVbpTn2x85D --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Nat Rev Gastroenterol Hepatol. 2022 Jun;19(6):351-366 Drugs. 2016 Jul;76(11):1067-79. Front Immunol. 2021; 12: 613591 J Appl Microbiol. 2009. Jun;106(6):1908-18 Exp Cell Res. 2015 May 1; 333(2): 195–200. Mediators Inflamm. 2017; 2017: 4806541. Parsons, G. McQuinn,R. 1971. Pale Blue [ Byrds] Byrdmaniax lp. https://youtu.be/Mh3J7GqrdzY?si=Kp0XfrwPtSi4vY6q Baker, G. 1967. "Blue Condition" [Cream]. Disraeli Gears lp. https://youtu.be/bjQjEyJwPpg?si=70Nye1AGPWsgG0hs Strauss, J.(II). 1866 "An der schönen blauen Donau", Op. 314 https://youtu.be/fHzhDKwYP2s?si=umxkaYC6nRvikezX --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References and simple equations PV = nRT where P is pressure (in atm), V is volume (in liters), n is number of moles and T is temperature (in K); R is a constant and is equal to 0.08206 L atm/moleK.  Molecular Shape including thickness(radius) of membrane curvature is v/al where v=volume,a=area per headgroup, and l=thickness of the hydrocarbon monolayer Guerra, D. Membrane Biochemistry notes --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

References Front Immunol . 2021 Mar 10:12:613591. Guerra, D. 2020's. Membrane Biochemistry Lectures Crosby, D., Kantner, P., and Stills, S. 1968. "Wooden Ships" [Jefferson Airplane ] from Volunteers lp. https://youtu.be/ROBaoiJK0wc?si=ABsxa4m4AjjAwoms Mendelsshon, F. 1830. "The Hebrides Overture"-Fingal's Cave.OP26. https://youtu.be/MdQyN7MYSN8?si=w9G1d0_5DFJn-tzx --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Dr. Mitchell Kronenberg is a Professor and President Emeritus at La Jolla Institute for Immunology. His lab studies how innate-like T cells adapt to different tissue environments. He talks about his work on MAIT cells and mucosal immunology, as well as his time leading the Institute.

Editor's Summary by Anthony Charles, MD, MPH, Associate Editor of JAMA, the Journal of the American Medical Association, for the April 2, 2024, issue.

The CBC (complete blood count) with differential is the most common lab test performed on patients. Practitioners often look at the ranges indicated in the CBC. However, they don't look closely at the five critical markers that can tell what's happening inside the patient's body.Learning how to read blood work better is essential to providing quality care. Becoming a Functional Blood Work Specialist is possible no matter how simple or complex your background is. Today, I share how some practitioners elevated their practice by incorporating functional blood work into their treatment package. I also discuss the five markers inside this standard blood test to help you discover the gold inside your patient's CBC.Open enrollment for the 90-day Functional Blood Work Specialist Program is happening now. I'd be honored to have you join this cohort. We start and end together, so you'll need to decide before February 29th is over. We begin March 1st. Get all the details and become certified at drkylieburton.com/90“No matter how simple your background is or how complex your background is, the blood work your patients have is loaded with gold.”- Dr. Kylie BurtonIn This Episode:What is the CBC?What is the WBC, and what do the numbers mean?What are Neutrophils?What are Lymphocytes?What are Monocytes?What are Basophils and Eosinophils?Why join the 90-Day Functional Blood Work Specialist Program?Resources:Join the 90-day Functional Blood Work Specialist Program - https://drkylieburton.com/90day/Learn How to Read the Blood Work Your Clients Already Have in a Better Way - https://drkylieburton.com/cbc-live/Why Are My Labs Normal? By Dr. Kylie Burton - https://drkylieburton.com/product/why-are-my-labs-normal/Connect with Dr. Kylie:Website - https://drkylieburton.com/Instagram - https://www.instagram.com/drkylieburton/Facebook - https://web.facebook.com/drkylieburton/YouTube - https://www.youtube.com/channel/UCdqJbAS6ocKydcjNiDQoauw

Grandpa Bill: Well partners, we've explored the battlefield, met the soldiers, and even dug into the kitchen of the immune system's fortress. But before we wrap up, let's give a standing ovation to the superstars of the show - the incredible white blood cells! Highlighting the Heroes: Neutrophils: "These frontline fighters, the neutrophils, are like the SWAT team of the immune system, gobbling up invaders with their mighty weapons." Lymphocytes: "But don't underestimate the B and T lymphocytes, partners! These clever strategists build antibodies, those little lock-and-key weapons that target specific nasties." Natural Killers: "And let's not forget the natural killer cells, the silent assassins who take out suspicious characters before they even cause trouble." Remember: It's a team effort! Each type of white blood cell plays a crucial role in keeping us healthy, so giving them the right fuel (healthy food, sleep, exercise) is essential. Bonus Tip: Want to supercharge your white blood cell squad? Check out BH Sales Kennel Kelp's natural supplements. Our high-quality kelp is packed with iodine and other minerals that help those immune warriors stay strong and ready for battle! Call to Action: Don't forget to share your immune-boosting tips and tricks on the BH Sales Kennel Kelp Facebook page! Head over to our website to grab some kelp-tastic supplements and give your immune system some love. And join us next time for another fascinating journey into the world of holistic healing! Outro Music (Fade Out) #WhiteBloodCellWarriors, #ImmuneSystemBootcamp, White Blood Cell Roundup: Meet the Immune System's Mighty Defenders! From Neutrophils to Natural Killers: Understanding the White Blood Cell Brigade Boost Your Immune System with White Blood Cell Superheroes Grandpa Bill is cracking open the gates of your body this week on The BH Sales Kennel Kelp Holistic Healing Hour! We're embarking on a fascinating journey into the realm of the incredible human immune system, the powerhouse keeping you healthy and ready to tackle anything life throws your way. Imagine white blood cells as valiant warriors, battling invaders at the border, while antibodies act as clever lock-and-key weapons. We'll explore the different battlezones within your body, from the gut to the skin, and discover how to support your internal defenders with the power of plant-based, wildcrafted foods. But wait, there's more! Grandpa Bill will delve into the world of BH Sales Kennel Kelp's natural supplements Leave your voicemail messages on The BH Sales Kennel Kelp Holistic Healing Hour Message Board and let your voice be heard! #ImmuneSystemPower, #PlantBasedHealing, #BHKennelKelpForHealth, #HolisticLiving,#BHSalesVoicemailChallenge, Share this episode with your friends and family! Let's spread the word about the power of holistic healing and empower everyone to take charge of their immune health. Remember, you have the power to build a fortress of health - join Grandpa Bill on this exciting journey and unleash your inner immune warrior! Holistic Health Secrets and Life-Sales Strategies with Grandpa Bill Nourish Your Soul, Boost Your Business: The BH Sales Kennel Kelp Holistic Healing Hour Experience Website: https://www.7kmetals.com/grandpabill Website:https://www.myctfo.com/index.html YouTube: Bill Holt@billholt8792 Social Media: https://www.facebook.com/bill.sales.524 Social Media:https://www.instagram.com/bradybrodyboy12/ Voicemail Message Board: https://podcasters.spotify.com/pod/show/bhsales JOIN US EVERY TUESDAY AT 6PM. EST. https://freedomsnap.org/Seth/ BH Sales Kennel Kelp Holistic Virtual Mall Patriot Supply Link:  ⁠⁠https://mypatriotsupply.com/?rfsn=5615494.137cb6⁠⁠ Health Ranger Link: ⁠⁠https://www.healthrangerstore.com/?⁠⁠rfsn=301296.96452b2&utm_source=HR_Affiliate&utm_campaign=14708&utm_affiliate=301296⁠⁠ ⁠⁠⁠Healer.com⁠⁠⁠: ⁠⁠⁠⁠https://www.HealerCBD.com/?ref=11⁠ --- Send in a voice message: https://podcasters.spotify.com/pod/show/bhsales/message

References J Immunol. 2009 Feb 1; 182(3): 1641–1647. Cell Reports 2015 10, 2043-2054DOI Virchows Archiv:European Journal of Pathology. 2020. 09456317, Vol. 476, Issue 2 Poe, EA. 1845. "the Raven" https://youtu.be/wAdQ3CcPHQU?si=2qpStYF2gdUJ4f35 Buddy Morrow and his Orchestra. 1960. "the Black Cat" https://youtu.be/9w_VL7oq-mE?si=XiorgTkvSGzJ4BK0 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Guest: Dr. Christopher Huerter, Professor and Division Chief Dermatology at Creighton University School of MedicineBreakthrough treatments: Checkpoint inhibitors like Ipilimumab have changed the way we treat melanoma. Now, a new cutting-edge adoptive cell therapy with tumor-infiltrating lymphocytes (TIL) has shown promise in metastatic melanoma treatment trials. A new phase III trial compares TIL to Ipilimumab immunotherapy as first- or second-line treatment in patients with advanced melanoma with remarkable results.Article:  https://www.nejm.org/doi/full/10.1056/NEJMoa2210233

While it's true that the majority of people will have a run-in with some kind of cancer in their lifetime, we need to remember that no 2 cancers are the same, and your overall metabolic health has a huge impact on how your body will manage the cancer and what your survival rates will be, plus which treatment path you should go down. To test your body's current metabolic health status when dealing with cancer, there's a number of simple blood tests you can run that will show how well (or poorly) your body is handling the tumor load.  You'll want to run the following tests: CBC and specifically look at WBC, Platelets, and the Neutrophil to Lymphocyte ratio Comprehensive Metabolic Panel - Creatinine, Liver enzymes, Alkaline Phosphatase Inflammatory markers - LDH, ESR, hs-CRP

Dr. Nadim Hallab is the CEO of Orthopedic Analysis and a professor at Rush University Medical Center in the department of Orthopedic Surgery. Dr. Hallab is an expert in metal hypersensitivity and implant degradation, whose research encompasses immune reactions to implant debris, modular junctions, peri-implant cell toxicity, and material surfaces for controlling immune responses. Over two decades, his group has made significant advancements in understanding implant debris interactions and improving implant performance. They've also developed renowned diagnostic methods for establishing metal sensitivity, especially as it relates to implanted hardware and medical devices. Dr, Hallab is the author of over 100 PubMed articles on metal hypersensitivity in regards to orthopedics, has authored and published many other scientific journal articles and has spoken on these subjects nationally and internationally, also sitting as an expert for the FDA on device panel hearings and other meetings. On this episode Dr. Hallab discusses the founding of Orthopedic Analysis, one of the world leaders in blood metal LTT allergy testing and the largest provider of this testing within the USA. We delve into the medical community's views on metal hypersensitivity, Lymphocyte Transformation Testing's clinical validation, and why the "gold standard" patch test falls short in diagnosing metal sensitivity. We explore ongoing efforts to gain support from the FDA, NIH, and insurance providers for LTT testing. We discuss differences between testing methodologies of the stateside Orthopedic Analysis lab, compared to overseas provider MELISA diagnostics and the overall provision and standards of LTT testing, as well as the different materials tested and tested against. Also concentration levels are better explained and a discussion on the shipping of biological samples occurs. Further conversation ensues around the future of metal implants in healthcare, along with the options of coating implants with alternative shielding agents like titanium nitride and carbon fiber, to camouflage allergenic metals from identification by the immune system, which may be less ideal than previously considered. The episode concludes with insights into the impact of COVID on the immune system and answers to questions from Metalhead followers. ~Links and Resources~ ~ Check out the Orthopedic Analysis website https://www.orthopedicanalysis.com/ ~ ~Access some of Dr. Hallab's scholarly and journal publications HERE: ~ ~To learn more visit ⁠HeavilyMetalled.com⁠. ~ Check out the “Heavily Metalled” resource page: ⁠https://www.heavilymetalled.com/resources⁠ ~ Follow Heavily Metalled on Facebook: ⁠https://www.facebook.com/HeavilyMetalled⁠ ~ Follow Heavily Metalled on Instagram: ⁠https://www.instagram.com/heavilymetalled/⁠ ~ Subscribe to Heavily Metalled on YouTube: ⁠https://www.youtube.com/@HeavilyMetalled⁠ ~ Check out our sponsor ⁠https://MELISA.org⁠ ***Many WONDERFUL, supportive special-interest communities exist for metal allergies and diet, hardware issues, medical devices, etc., online and on social media. They have many resources and often act as a collective think-tank. I owe many parts of my recovery to knowledge obtained in such groups. Search keywords to join these groups and find your tribe!***

In this episode, I explore the science behind these castor oil packs and how ricinoleic acid, a key component of castor oil, enhances lymphocyte activity and improves liver enzymes. I also touch on their potential role in supporting the liver during biotoxin illness. It's a deep dive into the benefits of a simple yet potent natural remedy. Topics: 1. Introduction to Castor Oil Packs - CIRS / Biotoxin Illness - Brief overview of castor oil packs - Their accessibility and cost-effectiveness 2. The Basics of Castor Oil Packs - How to create and apply a castor oil pack - Materials needed for the process - Preparation steps and protecting the area 3. Transdermal Absorption and Circulation - Ricinoleic acid's properties for transdermal absorption - Vasodilation and the role of heat packs - How ricinoleic acid is transported in the bloodstream 4. Ricinoleic Acid's Effects on Liver Function - The liver's vascularization and blood supply - Interaction of ricinoleic acid with liver cells (hepatocytes) - Proposed mechanisms of ricinoleic acid on liver function 5. Research on Castor Oil Packs - Presentation of studies on the effects of castor oil packs - Impact on immune function and liver health - Discussion on proposed mechanisms vs. observed outcomes 6. Step-by-Step Guide for Using Castor Oil Packs - Materials required for creating and applying packs - Detailed steps for applying a castor oil pack - Frequency and timing recommendations - Importance of consulting a healthcare professional Thanks for tuning in! Get Chloe's Book Today! "⁠⁠⁠⁠75 Gut-Healing Strategies & Biohacks⁠⁠⁠⁠" If you liked this episode, please leave a rating and review or share it to your stories over on Instagram. If you tag @synthesisofwellness, Chloe would love to personally thank you for listening! Follow Chloe on Instagram ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠@synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Follow Chloe on TikTok @chloe_c_porter Visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠synthesisofwellness.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to purchase products, subscribe to our mailing list, and more! Or visit ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠linktr.ee/synthesisofwellness⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ to see all of Chloe's links, schedule a BioPhotonic Scanner consult with Chloe, or support the show! Thanks again for tuning in! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support

References Curr Opin Pharmacol. 2021 Apr; 57: 107–116 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

Overview White Blood Cells Normal Value Range Pathophysiology Special considerations Abnormal values (high) Abnormal values (low) Nursing Points General Normal value range WBC 4500-10000/mcL Differential Neutrophils 40-60% Bands 3-5% >8% indicates signal to WBC for more production Infection or inflammation is severe Eosinophils 1-4% Basophils 0.5-1% Lymphocytes 20-40% Monocytes 2-8% Pathophysiology WBC Formed in the bone marrow Responsible for responding to foreign invaders Creating antibodies (immunity) Phagocytosis (eating bacteria or fungi) Multiple types with different purposes Neutrophils – inflammation and first response to invader Eosinophils – Inflammation Allergic response Parasites Basophils Inflammation Allergic response Lymphocytes Create antibodies Recognize antigens Destroy cells T Cells B Cells Natural Killer cells Monocytes Macrophages Engulf and destroy invaders Indicative of infection Special considerations Lavender top tube Will commonly be submitted for Complete Blood Count with differential Abnormal lab values Increased White Blood Cell count (leukocytosis) Infection Inflammation Trauma/Stress Pregnancy Asthma Allergic Reaction Decreased lab values (leukopenia) Systemic Lupus Erythematosus (SLE)/Rheumatoid arthritis Cancers Chemotherapy/Radiation Medications Neutropenic precautions Masks Gloves Wash hands Consider yourself infectious Prevent spread of infection to the patient Assessment Consider the overall WBC count plus abnormalities in differential Evaluate patient Signs or symptoms of: Trauma Inflammation Infection Therapeutic Management Antibiotic therapies where indicated by infection (followed by cultures to determine efficacy of antibiotics) Anti-inflammatories for inflammation Provide neutropenic precautions when necessary Nursing Concepts Lab Values Infection Control Patient Education Educate patient on the finishing any antibiotics completely. Do not stop prior, even if the patient says they are feeling better.

References Oncotarget 2021.12.(13) Cancers (Basel). 2020 Aug 1;12(8):213 Cancer Discov. 2022 Mar 1; 12(3): 856–871 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message

References Cancer Discov. 2022 Mar 1; 12(3): 856–871. Previous 5 lectures in Authentic Biochemistry and refs. contained therein https://youtu.be/dyy0p90GO2w --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message

Reference Authentic Biochemistry Lecture synthesis --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message

Reference J BiolChem. 2023 Mar; 299(3): 103019. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message

In this episode of SurgOnc Today, Genevieve Boland, MD, PhD, FSSO, of Massachusetts General Hospital – Vice Chair of the SSO Melanoma Disease Site Working Group is joined by fellow committee members, Rogerio Neves, MD, PhD, FACS, FSSO, from Moffitt Cancer Center and Amanda Kirane, MD, FACS, FSSO, from Stanford University. They discuss the current clinical application of tumor infiltrating lymphocytes (TILs) in melanoma, recent clinical trial results, advances in TILs production that have allowed for expanded patient access, and insight on appropriate patient or tumor selection for therapy.

References Dr Guerra Intermediary metabolic lecture notes-graduate biochemistry lecture archives Epigenetics. 2019; 14(12): 1183–1193. Drug Discov Today. 2017 Jan; 22(1): 186–193. --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message

A new research paper was published in Oncotarget's Volume 14 on May 4, 2023, entitled, “Human LY6 gene family: potential tumor-associated antigens and biomarkers of prognosis in uterine corpus endometrial carcinoma.” The human Lymphocyte antigen-6 (LY6) gene family has recently gained interest for its possible role in tumor progression. In this new study, researchers Luke A. Rathbun, Anthony M. Magliocco and Anil K. Bamezai from Villanova University carried out in silico analyses of all known LY6 gene expression and amplification in different cancers using TNMplot and cBioportal. In addition, the team analyzed patient survival by Kaplan-Meier plotter after mining the TCGA database. “We report that upregulated expression of many LY6 genes is associated with poor survival in uterine corpus endometrial carcinoma (UCEC) cancer patients.” Importantly, the expression of several LY6 genes is elevated in UCEC when compared to the expression in normal uterine tissue. For example, LY6K expression is 8.25× higher in UCEC compared to normal uterine tissue, and this high expression is associated with poor survival with a hazard ratio of 2.42 (p-value = 0.0032). Therefore, some LY6 gene products may serve as tumor-associated antigens in UCEC, biomarkers for UCEC detection, and possibly targets for directing UCEC patient therapy. “Further analysis of tumor-specific expression of LY6 gene family members and LY6-triggered signaling pathways is needed to uncover the function of LY6 proteins and their ability to endow tumor survival and poor prognosis in UCEC patients.” DOI - https://doi.org/10.18632/oncotarget.28409 Correspondence to - Anil K. Bamezai - anil.bamezai@villanova.edu Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28409 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - LY6 gene family, uterine cancer, tumor-associated antigen, patient survival, biomarker About Oncotarget Oncotarget is a primarily oncology-focused, peer-reviewed, open access journal. Papers are published continuously within yearly volumes in their final and complete form, and then quickly released to Pubmed. On September 15, 2022, Oncotarget was accepted again for indexing by MEDLINE. Oncotarget is now indexed by Medline/PubMed and PMC/PubMed. To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: SoundCloud - https://soundcloud.com/oncotarget Facebook - https://www.facebook.com/Oncotarget/ Twitter - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Media Contact MEDIA@IMPACTJOURNALS.COM 18009220957

References Guerra's notes --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support