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Vidcast: https://youtu.be/qhaBlo6cVAE An unexpected observation during a patient's awake neurosurgery confirms that laughter leads to a sense of calm and happiness. Surgeons at Emory University in Atlanta relate this fascinating, whimsical tale. A young patient with difficult to control epilepsy was undergoing awake neurosurgery to pinpoint the seizure focus. During the surgery, the surgeons inadventantly stimulated a pathway called the cingulum bundle, and the patient immediately began to smile, laugh, joke, and report an extremely calming and mood elevating experience that seemed to neutralize not only pain but also any scary thoughts. The neuroscientists repeated this same cingulum bundle stimulation in two other seizure patients to confirm their initial observation. They plan to use this stimulation technique in the future to calm nervous surgical patients and possibly to help treat depression. The good news is that you can trigger laughter and its calming and pain-neutralizing aftermath with a funny book or movie, some standup comedy, and looking for the funny side of life. Try it and enjoy! Kelly R. Bijanki, Joseph R. Manns, Cory S. Inman, Ki Sueng Choi, Sahar Harati, Nigel P. Pedersen, Daniel L. Drane, Allison C. Waters, Rebecca E. Fasano, Helen S. Mayberg, Jon T. Willie. Cingulum stimulation enhances positive affect and anxiolysis to facilitate awake craniotomy. Journal of Clinical Investigation, 2018; DOI: 10.1172/JCI120110 #laughter #calm #mood #elevation #epilepsy #seizure #awake #neurosurgery
Vidcast: https://youtu.be/cpb2nP4vYF0 An unexpected observation during a patient's awake neurosurgery confirms that laughter leads to a sense of calm and happiness. Surgeons at Emory University in Atlanta relate this fascinating, whimsical tale. A young patient with difficult to control epilepsy was undergoing awake neurosurgery to pinpoint the seizure focus. During the surgery, the surgeons inadventantly stimulated a pathway called the cingulum bundle, and the patient immediately began to smile, laugh, joke, and report an extremely calming and mood elevating experience that seemed to neutralize not only pain but also any scary thoughts. The neuroscientists repeated this same cingulum bundle stimulation in two other seizure patients to confirm their initial observation. They plan to use this stimulation technique in the future to calm nervous surgical patients and possibly to help treat depression. The good news is that you can trigger laughter and its calming and pain-neutralizing aftermath with a funny book or movie, some standup comedy, and looking for the funny side of life. Try it and enjoy! #laughter #calm #mood elevation #epilepsy #seizure #awake neurosurgery #health news #health tips Kelly R. Bijanki, Joseph R. Manns, Cory S. Inman, Ki Sueng Choi, Sahar Harati, Nigel P. Pedersen, Daniel L. Drane, Allison C. Waters, Rebecca E. Fasano, Helen S. Mayberg, Jon T. Willie. Cingulum stimulation enhances positive affect and anxiolysis to facilitate awake craniotomy. Journal of Clinical Investigation, 2018; DOI: 10.1172/JCI120110
Helen S. Mayberg, M.D., a behavioral neurologist with an international reputation for her pioneering research to map the brain circuits implicated in depression, talks about coauthoring our Cerebrum article, “Neuroimaging Advances for Depression” and her recent move from Emory’s School of Medicine to become the founding director of The Center for Advanced Circuit Therapeutics at Mt. Sinai.
Helen S. Mayberg, MD Professor, Psychology, Neurology and Radiology Dorothy C. Fuqua Chair in Psychiatric Neuroimaging and Therapeutics Emory University School of Medicine
Interview with Helen S. Mayberg, MD, author of Toward a Neuroimaging Treatment Selection Biomarker for Major Depressive Disorder
Host: Cathleen Margolin, PhD Guest: Helen Mayberg, MD Standard treatments for depression are effective in providing relief in most cases. However, some individuals suffer from depression that does not diminish despite adequate trials of antidepressants, psychotherapy and even electroconvulsive therapy. There is new hope for those suffering from treatment-resistant depression in the form of deep brain stimulation. Electrodes implanted in the brain that provide continuous current to a specific area of the brain has provided relief to subjects in groundbreaking new studies . Dr.Helen S. Mayberg, professor of Psychiatry and Neurology at Emory University School of Medicine joins host, Dr. Cathleen Margolin to discuss deep brain stimulation for depression. Dr. Mayberg's studies over the past 20 years in neural network models of mood regulation in health and disease have led to the recent development of a new intervention for treatment resistant patients using deep brain stimulation.