Clinician's Roundtable

Host: Jonathan Chung, MD Host: Seth Kligerman, MD Learn from experts about differentiating idiopathic pulmonary fibrosis (IPF) from other interstitial lung diseases and the role of radiology in effectively diagnosing IPF with a multidisciplinary team approach.

Guest: Ina Park, MD The United States has seen its largest increase in syphilis cases in the past five years. And with increases prevalent in every region, along with a shortage of medication, additional surveillance strategies and importation resources are necessary. Dive in for a discussion on the challenges and strategies to combat the spread of syphilis with Dr. Ina Park, Professor of Family Community Medicine at the University of California San Francisco School of Medicine.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Melanie Dispenza, MD The future therapeutic landscape for food allergy prevention is looking clearer as a drug typically used to treat hematologic malignancies has shown to prevent systemic anaphylaxis to allergens and increase patients' tolerance to peanuts. Along with this, other therapies are also in development for allergy treatment. To learn more, join Dr. Charles Turck as he dives deeper into this study and its findings with Dr. Melanie Dispenza, Assistant Professor of Medicine at Johns Hopkins University School of Medicine.

Host: Matt Birnholz, MD Guest: Donald Kohn, MD Third-generation lentiviral vectors were developed to improve upon safety measures and mitigate the risks of toxicity and replication that are typically associated with first- and second-generation therapies. These advancements may help enhance the functionality and utility of third-generation lentiviral vectors in various gene therapy applications. Learn more about the development, efficacy, and safety of third-generation lentiviral vectors with Dr. Matt Birnholz and Dr. Donald Kohn, Distinguished Professor at the University of California, Los Angeles. This non-certified educational series is produced and controlled by ReachMD, and is intended for healthcare professionals only.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Henry Rosenberg, MD Malignant hyperthermia is an inherited disorder primarily recognized by anesthesia professionals. And since this condition can have significant consequences on a patient's health, including their likelihood of surviving surgery, it's important to know how to diagnose and treat malignant hyperthermia emergencies in operating room settings. Join Dr. Charles Turck as he dives deeper into this topic with Dr. Henry Rosenberg, a member of the Board of Directors of the Malignant Hyperthermia Association of the United States.

Host: Charles Flexner, MD Daily oral therapy can have low adherence, which is why the field of long-acting formulations is rapidly advancing. Tune in to hear Dr. Charles Flexner discuss how long-acting regimens can address this problem of adherence and help patients living with HIV, tuberculosis, malaria, and other infectious diseases. Dr. Flexner is a Professor of Medicine of Pharmacology, Molecular Sciences, and International Health at Johns Hopkins University, and he also presented a session on this exact topic at the 2024 Conference on Retroviruses and Opportunistic Infections.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Prithviraj Bose, MD Normally, when a patient is newly diagnosed with myelofibrosis, the anemia is from the disease. And it's important to treat these patients with an individualized treatment plan as this could have a significant positive impact on their quality of life and outcome. To learn more, dive in with Dr. Charles Turck as he speaks with Dr. Prithvi Bose, Professor in the Department of Leukemia at the University of Texas MD Anderson Cancer Center.

Host: Jennifer Caudle, DO Guest: Sayantani Sindher, MD Recently, Omalizumab was studied in patients due to the avoidance of management and guidance when it comes to treating food allergies in children and adults. According to this doctor, approximately 45 percent of patients seen in his clinic have multi-food allergies that are not being met with current treatment options. So to explain his research, Dr. Jennifer Caudle is joined by Dr. Sayantani Sinder, Clinical Associate Professor of Medicine and Pediatric Allergy and Clinical Immunology Physician at Stanford Healthcare and Stanford Medicine Children's Health.

Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: Christin Iroegbu PhD, RN If left untreated, chronic kidney disease (CKD) can progress to end-stage renal disease, requiring dialysis or kidney transplant as the only treatment options. So communicating this to patients, along with chronic conditions that could contribute to this are key. To learn more about raising awareness of the causes of CKD and to help slow the progression, join Dr. Mary Katherine Cheeley who's speaking with Dr. Iroegbu, Co-Author of the article published in the Journal of Advanced Nursing, titled “An Integrative Review: Chronic Kidney Disease Awareness and the Social Determinants of Health Equity,” and T32 Postdoctoral Research Fellow at the Center for Health Outcomes and Policy Research at the University of Pennsylvania School of Nursing.

Host: Tauseef Ali, MD, FACG, AGAF Host: Sabina Ali, MD Host: Neil Nandi, MD, FACP Host: Tina Aswani-Omprakash, MPH A South Asian pediatric gastroenterologist discusses the epidemiology of IBD, distinct phenotypes, the latest clinical data from the mainland and diaspora, patient burden, and the importance of providing culturally competent care.

Guest: Douglas Jones, MD A recent study was done to show the side effects of diphenhydramine for allergic reactions, and one of the main detriments was that it could impair the patient by making them tired or sleepy. Another finding was that it doesn't work that quickly, so in turn, giving diphenhydramine in a severe allergic reaction could cause more harm than good. To learn more on what you should know before using diphenhydramine in allergic reaction situations and possible better solutions, tune in with Dr. Douglas Jones, Board-Certified Allergist and Immunologist with the Tanner Clinic in Layton, Utah.

Guest: Gates B. Colbert, MD, FASN A class of medications called SGLT2 inhibitors have been proven to make a major difference for patients with chronic kidney disease (CKD) with and without diabetes when added to angiotensin converting enzyme (ACE) and angiotensin receptor blockers (ARB) classes of medications. Several medications that have been well studied and approved by the FDA in the United States have shown progression of not only CKD but also cardiovascular events and overall mortality. To learn more about these medications, join Dr. Gates Colbert, Assistant Clinical Professor of Medicine at Texas A&M College of Medicine, and Nephrologist and Certified Hypertension Specialist at Kidney and Hypertension Associates of Dallas.

Host: Michael Greenberg, MD Guest: Chris Bundy, MD, MPH, FASAM Clinicians experiencing substance abuse disorder (SUD) may have some reluctance about utilizing a Physician Health Program; however, it's important to know what your resources are in terms of formal treatment and to seek a psychiatrist with addiction specialization. Dive into part two of this discussion to learn more about the valuable resources and programs that can help physicians recover from SUD with Dr. Michael Greenberg and Dr. Chris Bundy, Executive Medical Director of the Washington Physicians Health Program and Clinical Assistant Professor of Psychiatry at the University of Washington School of Medicine.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: John Hertig PharmD, MS, CPPS Here in the United States, we're investing a little more into cost effectiveness to make the best use of very limited healthcare resources. When ready-to-administer (RTA) syringe products were compared against traditional vial and syringe, there was a significant holistic cost effectiveness benefit. So what other benefits do we need to know about? Dive in with Dr. Charles Turck for a comprehensive review of RTA prefilled syringes with Dr. John Hertig, Vice Chair and Associate Professor of Pharmacy Practice at Butler University College of Pharmacy and Health Sciences in Indianapolis.

Host: Ashley Baker, MSN, PMHNP Guest: Chi D. Chu, MD, MAS The National Health and Nutrition Examination Survey found that kidney disease awareness among patients in the U.S. is very low. And alarmingly, the proportion of awareness has not changed much over the 15-year period of this study. To uncover more of the findings and how to improve CKD awareness, tune into this discussion with Psychiatric Nurse Practitioner Ashley Baker as she takes a deep dive with Dr. Chi D. Chu, Assistant Professor of Medicine in the Division of Nephrology at the University of California San Francisco and coauthor of the article published in the American Journal of Kidney Diseases, titled “CKD Awareness Among US Adults by Future Risk of Kidney Failure.

Host: Michael Greenberg, MD Guest: Chris Bundy, MD, MPH, FASAM Along with the general population, physicians are vulnerable to substance use disorder (SUD) with rates as high as 10 to 14 percent. And with demanding careers, stress and burnout can often exacerbate SUD. Tune into part one of this discussion with Dr. Michael Greenberg as he takes a deep dive into the prevalence of SUD and use characteristics among physicians with Dr. Chris Bundy, Executive Medical Director of the Washington Physicians Health Program and Clinical Assistant Professor of Psychiatry at the University of Washington School of Medicine. Read the original publication, titled "The Whole Physician: Physicians with Substance Use Disorder: Help is Available," which was published on Practical Neurology in November 2023.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Basil M. Kahwash, MD Patients with asthma who have experienced challenges with exercise may find that they are hesitant to exercise again in the future, or they may think it's not safe to pursue. However, artificial intelligence (AI) may be a useful tool in promoting exercise in asthma patients due to its ability to generate a personalized approach for the patient with a quick turnaround. Explore the benefits between AI and exercise in asthma patients with Dr. Basil Kahwash, Assistant Professor of Medicine on the Clinical Educator Track in the Department of Medicine at Vanderbilt University in Nashville, Tennessee. He also spoke about this topic at the 2023 Annual ANAC conference in his session, titled “Managing Co-Occurring Conditions: A Clinical Update.”

Host: Jennifer Caudle, DO Guest: Manpreet Mundi, MD Enteral nutrition intolerance is quite prevalent as it can be seen in up to 40 percent of patients who are tube fed. Due to the significant consequences of intolerance, there's an urgency to manage patients symptoms, and one option that's been shown to help is peptide-based tube feeding formulas. Joining Dr. Jennifer Caudle to talk about the management of enteral feeding intolerance with peptide-based tube feeding formulas is Dr. Manpreet Mundi, Professor of Medicine in the Department of Endocrinology at the Mayo Clinic College of Medicine and Science in Rochester, Minnesota. All trademarks are owned by Société des Produits Nestlé S.A., Vevey, Switzerland. ©2023 Nestlé

Guest: Michael T. Pulley, MD PhD The chronic inflammatory demyelinating polyneuropathy (CIDP) treatment objective for disease stabilization and long-term maintenance is to get the patient to a normal functioning state with as few fluctuations and relapses as possible. Dive in with Dr. Qihua Fan, Assistant Professor in the Department of Neurology at Virginia Commonwealth University.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Justin Reinert, PharmD Acute respiratory distress syndrome (ARDS) is a severe lung condition characterized by the rapid onset of widespread inflammation in the lungs, but inhaled epoprostenol can be used as a last-line treatment strategy for these patients. Learn more about this treatment option's efficacy and safety with Dr. Charles Turck and Dr. Justin Reinert, Assistant Professor of Clinical Pharmacy at the University of Toledo.

Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: Basil M. Kahwash, MD Patients with asthma could benefit greatly from exercising, and over time, it could lead to better asthma control. Dive into this episode to learn more about the findings from a recent study on exercise and asthma with Dr. Mary Katherine Cheeley and Dr. Basil Kahwash, Assistant Professor of Medicine on the Clinical Educator track in the Division of Allergy, Pulmonary, and Critical Care Medicine at Vanderbilt University in Nashville, Tennessee.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Ananta Paine, PhD The diagnosis of psoriatic arthritis has not been easy due to the lack of knowledge about an established biomarker. To learn more, join Dr. Charles Turck as he speaks with Dr. Ananta Piane, Principal Investigator and Research Assistant Professor at the University of Rochester Medical Center in Rochester, New York, to discuss his 500-patient cohort study to find out if there are underlying differences of psoriasis patients who did not convert to psoriatic arthritis with those who did.

Host: Charles Turck, PharmD, BCPS, BCCCP Emerging data over the years has shown the role of GLP-1 receptor agonists, not only in terms of their initial role in managing diabetes and blood sugar but also the secondary benefit of sometimes massive amounts of weight loss. However, there hasn't been a tremendous number of studies looking at the use of these agents in patients with HIV. Join Dr. Charles Turck as he dives into the data further with Dr. Darcy Wooten, Clinical Professor of Medicine and a Program Director for the University of California San Diego ID Fellowship Training Program in the Division of Infectious Diseases and Global Public Health.

Host: Andrew Wilner, MD, FACP, FAAN Guest: Neil Skolnik, MD The Global Initiative for Chronic Obstructive Lung Disease (GOLD) recently updated some of the recommendations for treating patients with chronic obstructive pulmonary disease (COPD). Two large conceptual changes occurred in this update: one is an increased emphasis on treating exacerbations, and the other is looking at decreasing mortality as an important treatment goal. Learn more about this and other key updates from the GOLD recommendations with Dr. Andrew Wilner and Dr. Neil Skolnik, Professor of Family and Community Medicine at the Sidney Kimmel Medical College of Thomas Jefferson University in Philadelphia.

Host: Jennifer Shu, MD, FAAP Guest: Steven H. Abman, MD Bronchopulmonary dysplasia is a chronic lung disease that can have significant impacts on a newborn's overall respiratory health, making it imperative to know how to recognize and treat it. Tune in to hear Dr. Jennifer Shu talk about the symptoms, impacts, and treatment of bronchopulmonary dysplasia with Dr. Steven Abman, a Professor in the Department of Pediatrics at the University of Colorado School of Medicine and the Director of the Pediatric Heart Lung Center at Children's Hospital Colorado.

Host: Dalmacio Dennis Flores, PhD, ACRN, FAAN According to a Gallup poll, Generation Z youth identify as LGBTQ more than previous generations. Given this increasing prevalence, clinicians need to know how to foster synergistic relationships between parents and LGBTQ+ youth. Here to discuss this important topic is Dr. Dalmacio Dennis Flores, an Assistant Professor at the University of Pennsylvania School of Nursing. He also spoke about this exact topic at the 2023 Annual ANAC conference in his session, titled “Synergy in Inclusive Sexual Health: Triadic Models Empowering LGBTQ+ Youth, Parents, and Nurses.”

Host: Jeffrey Kwong, DNP, MPH Managing co-occurring conditions in patients with HIV can be challenging. But by taking certain steps—like updating management guidelines, screening for complications, and implementing prevention strategies—we can overcome those challenges and improve the way we care for HIV patients with co-occurring conditions. Here to discuss those strategies is Dr. Jeffrey Kwong, a Professor in the Division of Advanced Nursing Practice at Rutgers University School of Nursing. He also spoke about this exact topic at the 2023 Annual ANAC conference in his session, titled “Managing Co-Occurring Conditions: A Clinical Update.”

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Kalpesh Thakkar, MD, MSCR Cow's milk protein allergy is the most common food allergy in infants. And overall, it's important to know that in general, the incidence of allergy is increasing worldwide. To take a deep dive, join Dr. Charles Turck as he speaks with Dr. Kalpesh Thakkar, Pediatric Gastroenterologist at Memorial Hermann Medical Group in Sugarland, Texas. All trademarks are owned by Société des Produits Nestlé S.A., Vevey, Switzerland. ©2023 Nestlé

Host: Jennifer Caudle, DO Guest: Katherine Bennett, MPH, RD, CLEC Caregivers and children often face challenges when trying to find a formula that's well-tolerated, and the burden of feeding intolerance extends to the healthcare system as well. Find out how blenderized whole food tube feeding whole food tube feeding formulas like Compleat Organic Blends can help address those challenges and benefit pediatric patients with Dr. Jennifer Caudle and Ms. Katherine Bennett, a registered dietitian at the Children's Hospital of Orange County in California. All trademarks are owned by Société des Produits Nestlé S.A., Vevey, Switzerland. ©2023 Nestlé

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: William R. Short, MD, MPH, AAHIVS As of January 2023, the breastfeeding guidelines for HIV patients were updated, and they now recommend supporting the parent's choice through shared decision-making. Joining Dr. Charles Turck to share what these new guidelines look like in practice and key counseling strategies for HIV patients is Dr. William Short. Dr. Short is an Associate Professor of Medicine and Infectious Disease at the University of Pennsylvania in Philadelphia, and he also spoke about this exact topic at the 2023 ANAC conference in his session, titled “New Recommendations for Infant Feeding for Persons with HIV in the United States.”

Host: Rachel Denyer, MD About one in every three people living with HIV has a positive hepatitis B core antibody. But how frequently does hepatitis B reactivation occur after a patient with HIV switches to an antiretroviral regimen that has no hepatitis B activity? Find out with Dr. Rachel Denyer as she shares key data she presented at IDWeek 2023 in the session titled “Hepatitis B Reactivation in Persons with HIV with Positive Hepatitis B Core Antibody After Switching to Antiretroviral Therapy Without Hepatitis B Activity.”

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Stuart M. Levitz, MD Treating fungal infections can be difficult due to the limited treatment options available, but could antifungal vaccines help change that? To catch us up on the progress being made in immunotherapeutic and vaccine strategies, Dr. Charles Turck speaks with Dr. Stuart Levitz about the “Antifungal Vaccines: Where Are We At?” session he presented at IDWeek 2023.

Host: Jeffrey Freiberg, MD, PhD The field of infectious diseases is always evolving thanks to new research studies, data, and treatment options. To help us catch up on some of these essential updates, Dr. Jeffrey Freiberg is here to give us an overview of the “What's Hot in ID in Clinical Science” session he helped develop for IDWeek 2023.

Host: Jay Fishman, MD With a global shortage of human organs, xenotransplantation offers a potential new way to save lives. But what are the immunologic barriers? Tune in as Dr. Jay Fishman, Director of Transplant Infectious Diseases and Compromised Host Program at Massachusetts General Hospital, recaps his session from the 2023 IDWeek.

Guest: Qihua Fan, MD There are three main first-line treatments for CIDP, and those are steroids, immunoglobulins, and plasmapheresis. So to walk us through the updated guidelines, we're joined by Dr. Qihua Fan, Neurology Specialist in the Department of Neurology at Virginia Commonwealth University School of Medicine in Richmond.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Allison Andreno Norful, PhD, MPhil, MSN, BSN, ANP-BC Emergency departments are demanding, causing ER nurses to experience high levels of work-related stress, and they're at a higher risk of burnout now more than ever before. But what are the causes and factors specific to emergency nurses that can lead to burnout, and why are these nurses leaving their positions? Those are the exact questions a recent study sought to answer, and here to break down the results with Dr. Charles Turck is Dr. Allison Norful, adult nurse practitioner and Assistant Professor of Nursing at Columbia School of Nursing.

Host: Jennifer Caudle, DO Guest: David Saperstein, MD When it comes to treating chronic inflammatory demyelinating polyneuropathy (CIDP) with subcutaneous immunoglobulin (SCIG), the patient can be trained by a professional to administer the treatment themselves. So what counseling strategies can we use to help patients successfully transition from intravenous to SCIG therapy? Join Dr. Jennifer Caudle as she gains insights from Dr. David Saperstein, Director of the Center for Complex Neurology, EDS, and POTS in Phoenix, Arizona, and Associate Professor of Clinical Neurology at the University of Arizona College of Medicine.

Guest: Sami Khella, MD While there are FDA-approved treatments for CIDP, patients remain, to a large extent, fairly disabled by this illness. However, there are several ways in which clinicians can work with their patients to provide the best care possible. Dive in with Dr. Sami Khella, Professor of Clinical Neurology at Penn Medicine University City in Philadelphia.

Guest: Terry M. Foster, MSN, RN, CEN, CPEN, CCRN, TCRN, FAEN Attendees can expect a wide range of education sessions, keynote presentations, networking events, and hands-on learning experiences from this year's Emergency Nurses Association (ENA) annual meeting. Hear from ENA President, Terry Foster, Critical-Care Clinical Nurse Specialist in the Emergency Departments at St. Elizabeth Healthcare, a Magnet-Designated Hospital, in Northern Kentucky, as he shares more details on the upcoming 2023 meeting.

Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: Valeria Cantos Lucio, MD HIV diagnoses in the United States have declined two-thirds since the start of the pandemic in the 1980s. However, the Latino community are still facing high risk of infections. To learn more on providing better access to care for these patients, join Dr. Mary Katherine Cheeley as she speaks with Dr. Valeria Cantos Lucio, Associate Professor of Medicine in the Department of Infectious Diseases at Emory University and an investigator at the Ponce de Leon research site.

Host: Mary Katherine Cheeley, PharmD, BCPS, CLS, FNLA Guest: Dylan Baker, MD Georgia has the highest rate of new HIV diagnoses out of any state in the country, and so it's imperative that we make this medication more accessible now in order to save future generations from living with HIV. To dive further into the benefits and challenges of this program, Dr. Mary Katherine Cheeley is joined by Dr. Dylan Baker, Assistant Professor of Medicine at Emory University and the Associate Medical Director of the Grady PrEP Clinic.

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Sorana Segal-Maurer, MD Research has shown that those living with HIV are more likely to be malnourished and experience nutrient deficiencies that play an essential role in their immunity. In the early days of HIV, a typical recommendation was to increase a patient's calorie count. To discuss how the focus on nutrition has changed now that this patient population is living much longer, Dr. Charles Turck is joined by Dr. Sorana Segal-Maurer, Director of Infectious Diseases at New York-Presbyterian Queens and Professor of Clinical Medicine at Weill Cornell Medicine in New York City.