Podcasts about DOI

Neither the ACOG nor SMFM recommend strict bed rest for preterm birth prevention, or nor preeclampsia. Yet tradition often conflicts with evidence. A prior 2009 survey of MFM specialists, published in the AJOG, on the use of bed rest revealed that 71% used activity restriction in their practice for arrested preterm labor, despite the majority believing it had minimal or no benefit. The authors concluded, “Because most obstetricians in our survey indicated they would prescribe bed rest believing it was associated with minimal or no benefit, it is possible that even if a randomized, prospective trial showed no benefit associated with bed rest, it would still remain a common recommendation.” This brings us to a brand new publication from the Green Journal which is an ancillary study of two randomized trials of preterm birth prevention in women with a short cervical length. These authors sought to evaluate the amount of physical activity in patients at high risk for preterm birth and pregnancy latency and preterm birth. What did they find? It is a bit shocking. Listen in for details.1. Fox, Nathan S. et al. The recommendation for bed rest in the setting of arrested preterm labor and premature rupture of membranes. American Journal of Obstetrics & Gynecology, Volume 200, Issue 2, 165.e1 - 165.e6 https://www.ajog.org/article/S0002-9378(08)00909-5/fulltext2. Sciscione, Anthony C. DO; Booker, Whitney A. for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units (MFMU) Network, Bethesda, Maryland. Activity Restriction in Pregnancy and the Risk of Early Delivery: The AWARE Study. Obstetrics & Gynecology ():10.1097/AOG.0000000000006225, February 19, 2026. | DOI: 10.1097/AOG.0000000000006225 https://journals.lww.com/greenjournal/pages/articleviewer.aspx?year=9900&issue=00000&article=01460&type=FulltextVisit our SPONSOR's Webpage for information on the Hemorrhage View C-Section Drape: www.perspectivemedical.org

Show Notes & Links (Sources) (In the order they appear above.) DOI finalizes NEPA procedure overhaul BLM Director nominee Steve Pearce confirmation hearing USFWS Wildlife & Sport Fish Restoration apportionments ($1.2B+) California SB 1305 — grizzly bear “roadmap” proposal Idaho elk depredation plan near Emmett (move or remove ~100 elk) Wyoming corner crossing bill — update as it heads to Senate Colorado wolf depredation compensation pressure / claim totals (reported) Catalina Island deer eradication plan / permit controversy Louisiana “live alligator on Bourbon Street” arrest Learn more about your ad choices. Visit megaphone.fm/adchoices

ReferencesSCIENTIFIC REPORTS 2016 | 6:34594 | DOI:10.1038/srep34594 Seminars in Immunology 2025. V. 78,Jun, 101954Front Immunol. 2025 Jan 8:15:1515715Telemann, GP. 1735. Sinfonia Spirituosa TWV 40&50https://open.spotify.com/album/2nJX3LIjdAbNIGR3qbQaBI?si=VF-7aHcBS_qOkEsl34LdKQ

In this episode, Lillian Erdahl, MD, FACS, is joined by Jessica Liu, MD, MS, MPH, from the Department of Surgery, Harbor UCLA Medical Center. They discuss Dr Liu's recent article, “Identifying Diagnostic Gaps and Mitigation Strategies for Older Adult Emergency General Surgery Patients: A Scoping Review,” in which the authors identified the current diagnostic issues, clinical tools, and clinician feedback strategies in the older adult emergency general surgery (EGS) setting. While challenges unique to older adults exist, variability in the use of tools to improve identification of older adult conditions in EGS and gaps in feedback to improve diagnosis remain.   Disclosure Information: Drs Erdahl and Liu have nothing to disclose.   To earn 0.25 AMA PRA Category 1 Credits™ for this episode of the JACS Operative Word Podcast, click here to register for the course and complete the evaluation. Listeners can earn CME credit for this podcast for up to 2 years after the original air date.   Liu, Jessica K MD, MS, MPH; Peters, Xane D MD, MS; Remer, Sarah L MD; Beestrum, Molly MLIS; Cooper, Zara MD, FACS, MPH; Russell, Marcia M MD, FACS; Hall, Bruce L MD, FACS, PhD; Ko, Clifford Y MD, FACS, MSHS, MS. Identifying Diagnostic Gaps and Mitigation Strategies for Older Adult Emergency General Surgery Patients: A Scoping Review. Journal of the American College of Surgeons 241(5):p 904-916, November 2025. | DOI: 10.1097/XCS.0000000000001480   Learn more about the Journal of the American College of Surgeons, a monthly peer-reviewed journal publishing original contributions on all aspects of surgery, including scientific articles, collective reviews, experimental investigations, and more.   #JACSOperativeWord   Copyright © 2026 by the American College of Surgeons (ACS). All rights reserved.   The contents of these materials may be cited in academic publications but otherwise may not be reproduced, disseminated, or transmitted in any form by any means without the express written permission of ACS. These materials may not be resold nor used to create revenue-generating content by any entity other than the ACS without the express written permission of the ACS. The contents of these materials are strictly prohibited from being uploaded, shared, or incorporated in any third-party applications, platforms, software, or websites without prior written authorization from the ACS. This restriction explicitly includes, but is not limited to, the integration of ACS content into tools leveraging artificial intelligence (AI), machine learning, large language models, or generative AI technologies and infrastructures. 

“The reality is none of us use light continuous forces.” “Friction is awesome. Friction is great, we would be miserable if there was no friction… (with) uncontrolled movement everywhere” “Segmented arch mechanics are very tough to gain three-dimensional control over the tooth.”  “The last major landmark in fixed appliance and in orthodontics was the pre-adjusted edgewise appliance.” “The root is not moving according to the wish of the orthodontist (with aligners)” I'm joined by Madhur Upadhyay for a deepexploration of biomechanics, biology, and the true limits of orthodontic innovation. We examine advances in appliances, aligners, and digital workflows and why they have, as of yet, not improved speed or quality of clinical outcomes,and innovation is still governed by the same biological constraints that dictated tooth movement a century ago. However progress has been significant in workflows for both fixed and aligner therapy. We also discuss why complex biomechanics arerarely implemented in routine practice, whether pre-adjusted appliances were the last major landmark innovation, and what aligners can, and cannot, achieve in terms of root control in terms of biomechanics. The conversation extends toartificial intelligence in diagnosis and treatment planning, asking whether automation enhances clinical care or gradually replaces critical thinking. We conclude with thoughts of micro and nano-plastics and the focus needed on this topic in orthodontics. Please like and subscribe if you find it useful! Please visit the website for this interview podcast:https://orthoinsummary.com/the-hidden-biomechanics-of-fixed-appliances-aligners-orthodontics-in-interview-madhur-upadhyay/ .Publications by Madhur UpadhyayBiomechanics of clear aligners: hidden truths & firstprinciples 2022 https://doi.org/10.1016/j.ejwf.2021.11.002ClearAligners in Extraction-Based Orthodontic Treatment: A Systematic Review andMeta-Analysis 2026 DOI: 10.1111/ocr.70052   #OrthodonticsInSummary# Madhurupadhyay #Orthodontics#biomechanics#TADs#OrthodonticsInInterview#FarooqAhmed#OrthodonticBiomechanics#DentalEducation Farooq Ahmed

BUFFALO, NY – February 25, 2026 – A new #editorial perspective was #published in Volume 17 of Oncotarget on February 20, 2026, titled “CAR-T therapy: Trailblazing CAR(ing) in cancer treatment.” Led by Uzma Saqib — with corresponding author Krishnan Hajela from the School of Life Sciences, Devi Ahilya Vishwavidyalaya — the perspective reviews recent clinical and translational advances in chimeric antigen receptor T-cell (CAR-T) therapy and highlights both its promise and its remaining barriers. The piece synthesizes recent clinical advances in hematologic malignancies and emerging applications in solid tumors, while focusing attention on safety (for example, cytokine release syndrome and neurotoxicity), resistance, antigen specificity, and access disparities. The authors summarize the CAR-T workflow (leukapheresis → genetic modification and expansion → infusion) and note major recent clinical gains — including improved outcomes in leukemia, lymphoma, and multiple myeloma — that support wider adoption of cellular immunotherapy approaches. They emphasize that despite these advances, important clinical challenges remain, particularly for solid tumors, where antigen selection, tumor microenvironment, and T-cell trafficking limit efficacy. At the same time, the perspective highlights technological and clinical strategies under development to overcome these obstacles, including next-generation CAR designs and improved supportive-care protocols. “Despite its promise, CAR T-cell therapy faces several critical challenges.” The authors call out clear next steps for the field: (1) continued refinement of CAR constructs (dual-targeting, switchable/on-off systems, armored CARs) to improve specificity and reduce on-target/off-tumor toxicity; (2) improved management protocols and prophylactic measures to mitigate CRS and neurotoxicity; (3) expanded investigation of allogeneic or alternative CAR-T platforms to address manufacturing, cost, and access barriers; and (4) focused translational studies to improve T-cell trafficking and efficacy in solid tumors. They also highlight equity issues — socioeconomic and racial disparities that limit access to CAR-T — and urge that broad deployment plans include strategies to expand availability and affordability. DOI - https://doi.org/10.18632/oncotarget.28836 Correspondence to - Krishnan Hajela - hajelak@gmail.com Abstract video - https://www.youtube.com/watch?v=T4hbwPToVKI Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28836 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, CAR-T therapy, therapeutic approaches To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

This week on the Nutshell , Daisy and Clare discuss whether paying more for organic produce pays off in terms of health benefits. There are lots of things to think about from pesticide burden to the nutrient values in the foods themselves. But with ever rising food bills,  should you prioritise organic, or can we afford not to? Smith-Spangler C, Bravata DM, Hunter-Goren A, et al.“Are organic foods safer or healthier than conventional alternatives? A systematic review.”Annals of Internal Medicine, 2012; 157(5):348–366.DOI: 10.7326/0003-4819-157-5-201209040-00007Baranski M, Średnicka-Tober D, Volakakis N, et al.Higher antioxidant and lower cadmium concentrations and lower incidence of pesticide residues in organically grown crops: a systematic literature review and meta-analyses.British Journal of Nutrition. 2014;111(5):794–811.doi: 10.1017/S000711451300284XBaudry, J., Assmann, K. E., Touvier, M., Allès, B., Seconda, L., Latino-Martel, P., Hercberg, S. (2018). Association of frequency of organic food consumption with cancer risk: Findings from the NutriNet-Santé prospective cohort study.mJAMA Internal Medicine, 178(12), 1597–1606.https://doi.org/10.1001/jamainternmed.2018.4357https://www.ewg.org/foodnews/dirty-dozen.phphttps://www.pan-europe.info/https://www.pan-uk.org/https://hodmedods.co.uk/If you'd like to support our work and be part of a growing community of like-minded people working towards creating a healthier and more sustainable future please join the Plant-Based Health Professionals UK following the link below:https://plantbasedhealthprofessionals.com/membershipYou don't have to be a health care professional to join, but by doing so you're not only supporting our work, you'll be improving your own health;  with membership starting from as little as £15 a year, join us now and be part of the change you want to see.

In this conversation, Dr. Iman Farajallah shares her profound experiences and insights as a psychologist working with trauma, particularly in war zones like Gaza. She discusses her personal background, the impact of war trauma on children, and her efforts to give a voice to those affected. The conversation also touches on the challenges of mental health support in Gaza and the concept of complex continuous trauma, highlighting the ongoing struggles faced by the Palestinian population. This conversation delves into the profound and complex trauma experienced by the population of Gaza, particularly focusing on the impact on children. The discussion highlights the continuous nature of trauma, the intergenerational effects, and the parallels with other marginalized communities. Dr. Farajallah shares insights from her work training first responders and supporting refugees, as well as her personal journey of healing through spirituality. Watch on YouTube: https://youtu.be/-yxX3XhmWYU Follow us! Instagram: https://www.instagram.com/behaviourspeak/ LinkedIn:  https://www.linkedin.com/in/behaviourspeak/ Contact: LinkedIn https://www.linkedin.com/in/dr-iman-farajallah-psyd-6aa190149/ YouTube https://www.youtube.com/@dr.imanfarajallah3658   Links:  My Life Is a War: Voices of Traumatized Palestinian Children under Israeli Occupation https://www.amazon.ca/Life-War-Traumatized-Palestinian-Occupation/dp/B0D378QVCX Gaza's Children: Innocence Lost - 8 min video with some of the interviews by Dr. Farajallah with children in Gaza  https://www.youtube.com/watch?v=X4T5NxztIfw&t=1s The Invisible Wounds of Palestinian Children https://www.psychiatrictimes.com/view/the-invisible-wounds-of-palestinian-children Interview on Al Jazeera https://www.aljazeera.com/video/the-stream/2024/1/9/how-does-the-war-on-gaza-affect-mental-health-of-palestinian-children Interview on CBC  https://www.cbc.ca/player/play/audio/1.7053750 Articles by Dr. Farajallah Farajallah I. Health and mental health services in Gaza: A system under siege. Anatolian Clin. 2024;29(Special Issue on Gaza):22-3.  Farajallah, Iman. Continuous Traumatic Stress in Palestine: The Psychological Effects of the Occupation and Chronic Warfare on Palestinian Children. World Social Psychiatry 4(2):p 112-120, May–Aug 2022. | DOI: 10.4103/wsp.wsp_26_22  Farajallah I. Behind the Rubble: Psychological trauma of wars and human rights abuses on women and children in Gaza. Anatolian Clin. 2024;29(Special Issue on Gaza):119-36.  Farajallah, I. (2018). Children of War: Psychological Impacts of War and Postwar Trauma on the Palestinian Children in the Gaza Strip (Doctoral dissertation, Sofia University). Related Behaviour Speak Episodes Episode 232: Behaviour Analysis in Sudan with Salma Abdelrahmanabdalla https://www.behaviourspeak.com/e/episode-232-behaviour-analysis-in-sudan-with-salma-abdelrahmanabdalla-med-iba-qba/ Episode 197: Understanding Moral Injury with Dr. C. Richard Spates https://www.behaviourspeak.com/e/episode-197-understanding-moral-injury-with-dr-c-richard-spates/ Episode 191: Behaviour Analysis in Belarus with Анна Калиновская, M.A., BCBA, IBA (Hanna Kalinouskaya) https://www.behaviourspeak.com/e/behaviouranalysis-in-belaruswith-hannakalinouskaya-bcba-iba/ Episode 184 Behaviour Analysis in Ukraine with Alla Moskalets https://www.behaviourspeak.com/e/episode-184-behavior-analysis-in-ukraine-with-alla-moskalets/ Episode 176: Religion, Spirituality, and Mental Health with Dr. Janice Parker https://www.behaviourspeak.com/e/episode-176-religion-spirituality-and-mental-health/ Episode 139: Threads of Hope: Addressing Trauma Amid War and Civil Discord with Sawsan Razzouk, M.A., BCBA https://www.behaviourspeak.com/e/episode-139threads-of-hope-addressing-trauma-amid-war-and-civil-discord-with-sawsan-razzouk-ma-bcba/ Episodes 31 and 32: Special Series on Supporting Refugees from Ukraine Episode 1 and 2  https://www.behaviourspeak.com/e/episode-31specialseries-onsupporting-refugeesfromukraine-episode-1coordinating-supports-forrefugee-families-ofchildrenwithdisabilities-with-sophie/ https://www.behaviourspeak.com/e/episode-32specialseries-onsupporting-refugeesfromukraine-episode-2tipson-providing-directsupport-toukrainianrefugee-families-with-autistic-children/

Chris Mason unfiltered and doesn't hold back as we spend over an hour breaking down the last month "Stop moaning about s**t that don't matter"

BUFFALO, NY — February 24, 2026 — A new #research paper was #published in Volume 18 of Aging-US on February 10, 2026, titled “Aging-associated mitochondrial circular RNAs.” Led by first author Hyejin Mun from the University of Oklahoma — with corresponding authors Je-Hyun Yoon from the University of Oklahoma and Young-Kook Kim from Chonnam National University Medical School — the study profiles mitochondrial circular RNAs in Peripheral Blood Mononuclear Cells (PBMCs) from young and old human cohorts and probes how mitochondrial circRNAs and the mitochondrial RNA-binding protein GRSF1 relate to mitochondrial metabolism and cellular senescence. Using total RNA sequencing of PBMCs from young and old donors and complementary cell-based experiments, the authors report that a large fraction of circular RNA junctions originates from the mitochondrial genome, with MT-RNR2 producing the most abundant circular junctions. They show that circMT-RNR2 levels are depleted in older cohorts and in replicative senescence of human fibroblasts, and that the mitochondria-localized RNA-binding protein GRSF1 interacts with both linear and circular MT-RNR2. Loss of GRSF1 reduced circMT-RNR2 levels, decreased mitochondrial TCA intermediates (fumarate and succinate), and accelerated cellular senescence and mitochondrial dysfunction — findings that link mitochondrial circRNAs to mitochondrial energetics and proliferative status in younger cells. “Taken together, our findings demonstrate the existence and possible function of circular MT-RNR2 during human aging and senescence, implicating its role in promoting the TCA cycle.” The authors note key limitations and outline next steps: clarifying the biogenesis mechanism of mitochondrial circular RNAs (including whether trans-splicing contributes), mapping direct interactions between mitochondrial transcripts and metabolic enzymes, and performing mechanistic studies (in vivo and in additional human cohorts) to test how circMT-RNR2 and GRSF1 influence mitochondrial energetics and organismal aging. These follow-ups will determine whether mitochondrial circular RNAs are actionable targets for modulating mitochondrial metabolism or delaying aspects of cellular aging. DOI - https://doi.org/10.18632/aging.206354 Corresponding authors - Je-Hyun Yoon - jehyun-yoon@ou.edu, and Young-Kook Kim - ykk@jnu.ac.kr Abstract video - https://www.youtube.com/watch?v=f8uZ6_tcOHw Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206354 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, circular RNA, MT-RNR2, GRSF1, TCA cycle To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-473 Overview: Join us as we review long-term outcomes from a recently published trial on prostate-specific antigen (PSA) testing and prostate cancer mortality. Learn how updated evidence informs shared decision-making and balances early detection with potential harms. Equip yourself to guide patients through nuanced discussions on PSA testing's limitations, mortality data, and meaningful clinical impact. Episode resource links: N Engl J Med 2025;393:1669-80. DOI: 10.1056/NEJMoa2503223 Recommendation: Prostate Cancer: Screening | United States Preventive Services Taskforce Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

This week's Recast is from April 2020. Why This Episode Matters Now:In 2022, the war in Ukraine revealed something our partners had been experiencing but we hadn't fully articulated: the traditional model of intact, homogeneous teams wasn't sufficient for the emerging operational environment. Individuals with diverse expertise, geography, language, and allegiances needed to rapidly converge into what we call Tactical Swarms—heterogeneous cross-functional units that form, solve emergent problems, and disperse.Our recent white paper, The Fourth Generation of Military Special Operations Selection & Assessment, explores this evolution in depth. But six years ago, Preston laid the foundational concepts in this conversation with Coleman.What the Research Shows:Many operators who excelled at teamwork—performing with known, homogeneous teams—struggled with teaming: the ability to rapidly build cohesion within heterogeneous groups. This episode examines why routine versus critical communication and field observations across special operations, emergency medicine, and other high-stakes environments. In this episode, Preston and Coleman describe how tactical swarms and X teams differ from traditional team structures, and they distinguish between routine and critical communication and when teams must shift between them. Recent Research:Cline, P.B. (2026). The Fourth Generation of Military Special Operations Selection Assessment: A Community of Praxis [White paper]. Mission Critical Team Institute. DOI 10.13140/RG.2.2.28255.73121. https://missioncti.com/wp-content/uploads/2026/02/The-Fourth-Generation-of-Military-Special-Operations-Selection-Assessment_Final_2-Feb-26.pdf Falk, D., Cline, P., Donegan, D., & Mehta, S. (2023). A Novel Framework for Routine Versus Critical Communication in Surgical Education—Don't Take It Personally. Journal of the American Academy of Orthopaedic Surgeons, 31(3), 115–121. https://doi.org/10.5435/JAAOS-D-22-00912 https://missioncti.com/wp-content/uploads/2023/08/FINAL-A-Novel-Framework-for-Routine-Versus-Critical.pdf If you find value in this discussion, the best way to support our work and stay up to date on future episodes is to subscribe and leave us a quick rating or review. It helps us reach more people who need to hear these conversations.This episode contains a term that may be offensive; it is used to describe gendered communication dynamics. We have included it to accurately represent the event, and it is intended for educational purposes only.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-473 Overview: Join us as we review long-term outcomes from a recently published trial on prostate-specific antigen (PSA) testing and prostate cancer mortality. Learn how updated evidence informs shared decision-making and balances early detection with potential harms. Equip yourself to guide patients through nuanced discussions on PSA testing's limitations, mortality data, and meaningful clinical impact. Episode resource links: N Engl J Med 2025;393:1669-80. DOI: 10.1056/NEJMoa2503223 Recommendation: Prostate Cancer: Screening | United States Preventive Services Taskforce Guest: Robert A. Baldor MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

In this episode Associate Editor Dr. George Cotsarelis (University of Pennsylvania) and author Dr. Ralf Paus (University of Manchester) discuss the Review article by Altendorf on male pattern androgenetic alopecia. We uncover the physiology and function of hair in a wide-ranging and engaging conversation. In addition to producing pigmented protein fibers, the “mini organ” that makes our hair shaft not only senses the environment, it chemosenses the environment. According to Dr. Paus, hair can smell, taste, and see! What is the future of hair research? Listen now and find out more about this fascinating topic.   Sabrina Altendorf, Marta Bertolini, Alizée Le Riche, Antonella Tosti, and Ralf Paus Frontiers in the physiology of male pattern androgenetic alopecia: beyond the androgen horizon Physiological Reviews, published September 15, 2025. DOI: 10.1152/physrev.00005.2024

O grupo CEPCOM (Crítica da Economia Política da Comunicação) da Universidade Federal de Alagoas (Ufal) inicia um novo formato do ciclo de leituras, voltado à formação da base da Economia Política da Comunicação com mestrandas e mestrandos.Este episódio discute o artigo "Indústria Cultural e capitalismo tardio: Origens da Economia Política da Comunicação no Brasil em Mercado Brasileiro de Televisão" (Bastos, 2020). O texto foi apresentado por Lucas Souza (mestrando em Comunicação da UEL); com comentários de Vitória Rocha (mestranda em Comunicação da Ufal), Anderson Santos (professor dos mestrados em Comunicação da UEL e da Ufal) e Júlio Arantes (professor da Ufal).ReferênciaBASTOS, M. D. Indústria Cultural e capitalismo tardio: Origens da Economia Política da Comunicação no Brasil em Mercado Brasileiro de Televisão. Chasqui, Quito, n. 142, p. 187-202, dez. 2019/mar. 2020. DOI: https://doi.org/10.16921/chasqui.v1i142.4121. Disponível em: https://revistachasqui.org/index.php/chasqui/article/view/4121. Acesso em: 20 fev. 2026.Referências citadasBOLAÑO, C. (Coord.). Economía política de la comunicación y la cultura en América Latina (1970 y 1980). Buenos Aires: CLACSO, 2022. Disponível em: https://biblioteca-repositorio.clacso.edu.ar/bitstream/CLACSO/170046/1/Economia-politica-comunicacion.pdf. Acesso em: 20 fev. 2026.REVISTA EPTIC. v. 27 n. 3 (2025): Perspectivas críticas de abordagem da Publicidade - A embalagem do Sistema 40 anos depois. Disponível em: https://periodicos.ufs.br/eptic/issue/view/1434. Acesso em: 20 fev. 2026.

BUFFALO, NY — February 19, 2026 — A new #research paper was #published in Volume 18 of Aging-US on February 8, 2026, titled “Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV.” In this study, co-first authors Alan Tomusiak from the Buck Institute for Research on Aging and the University of Southern California, and Sierra Lore from the Buck Institute for Research on Aging and the University of Copenhagen, together with corresponding author Eric Verdin from the Buck Institute for Research on Aging, developed a new single-cell transcriptomic clock called T immune cell transcriptomic clock (Tictock) to measure aging in specific immune cells. Immune aging increases susceptibility to infection, cancer, and chronic inflammatory disease. Most aging clocks, used to measure it, rely on bulk measurements from mixed cell populations. As a result, they cannot determine whether age-related signals reflect shifts in cell proportions or true molecular aging within defined immune cells. To address this limitation, the research team used single-cell RNA sequencing, a method that measures gene expression in individual cells. They analyzed nearly two million immune cells from the blood of healthy adults to develop Tictock. This tool integrates automated classification of six canonical T cell subsets with cell-type specific age prediction models. This design enables the separation of systemic aging, reflected by changes in cell proportions, from intrinsic aging, which occurs within individual cells. When the team applied Tictock to patients with acute COVID-19, they found two clear effects. First, COVID-19 altered T cell composition, including significant reductions in naïve CD8 and naïve CD4 T cells. Second, the infection increased the biological age of naïve CD8 T cells. In people living with HIV who were receiving long-term antiretroviral therapy, T cell proportions remained largely stable. However, naïve CD8 T cells still showed signs of accelerated aging. The study also uncovered shared biological pathways linked to immune aging. Many of the genes that predicted age were involved in ribosomes, the structures that help cells produce proteins. The researchers also observed that older immune cells often had shorter average transcript lengths, a feature previously linked to aging. These findings suggest that changes in protein production and gene regulation play an important role in immune decline. “Gene Ontology enrichment of 209 genes shared across six clock models identified common pathways including the cytosolic small ribosomal subunit, TNF receptor binding, and cytosolic ribosome components.” Overall, Tictock was designed to measure relative aging within defined T cell populations rather than overall biological aging. By distinguishing systemic from cell-intrinsic immune aging, it provides a clearer understanding of how viral infections such as COVID-19 and HIV reshape immune function. This approach enables the study of immune aging at single-cell resolution and may support improved immune risk assessment in clinical and research settings. DOI - https://doi.org/10.18632/aging.206353 Corresponding author - Eric Verdin - EVerdin@buckinstitute.org Abstract video - https://www.youtube.com/watch?v=_r3AF7OrgKY Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts To learn more about the journal, please visit https://www.Aging-US.com​​. MEDIA@IMPACTJOURNALS.COM

We recently covered an SMFM abstract that was presented at the annual Pregnancy Meeting held in early February 2026. The authors were from my Alma Mater, UT Southwestern/Parkland Hospital. This was a well-done study comparing 162 milligrams aspirin to 81 milligrams of aspirin. The results were very encouraging! However, aspirin definitely has an awkward acumen. It would be wonderful if ALL the data just leaned in the same direction... but it doesn't! Enter our podcast family member, and my friend Alex. Alex sent me an incredible and insightful message which was a rebuttal to my Southwestern colleagues' findings. In this episode you'll hear Alex's rebuttal and clinical conundrum, and we will explain why these two seemingly paradoxical findings makes sense. Listen in for details.1. Khander, Amrin MD; Thomas, Charlene MS; Matthews, Kathy MD; Christos, Paul DrPH; Alcus, Claire BA; Alam, Tanvir BS; Bush, Leah BA; Deshmukh, Diksha BA; Chasen, Stephen T. MD; Riley, Laura E. MD; Skupski, Daniel W. MD; August, Phyllis MD, MPH; Malha, Line MD, MS. Comparison of 162 mg and 81 mg Aspirin for Prevention of Preeclampsia: A Randomized Controlled Trial. Obstetrics & Gynecology 147(1):p 87-96, January 2026. | DOI: 10.1097/AOG.0000000000006100

Have a client that wants to switch Med Supp plans? If they live in a Med Supp birthday rule state, it might be easier than you think! Learn more about the states and their rules in this ASG Podcast episode.   Read the text version  

BUFFALO, NY — February 18, 2026 — A new #editorial was #published in Volume 18 of Aging-US on February 8, 2026, titled “Polyploidy-induced senescence: Linking development, differentiation, repair, and (possibly) cancer?” In this editorial, Iman M. Al-Naggar of the University of Connecticut School of Medicine, UConn Health, and the University of Connecticut Center on Aging, with George A. Kuchel of the University of Connecticut Center on Aging, examines the biological and clinical significance of polyploidy-induced senescence. The authors discuss how this process may contribute to normal tissue development and long-term repair, while also influencing cancer risk. Their perspective centers on the bladder and outlines how aging-related cellular changes may shape tumor initiation. Aging remains the strongest risk factor for bladder cancer, which is predominantly of urothelial origin. Cellular senescence is defined as a stable growth arrest in which cells remain metabolically active but no longer divide. Polyploidy refers to cells that contain extra copies of their genome. Although polyploidy is frequently associated with cancer, it also occurs in several healthy tissues as part of normal development and adaptation to stress. The editorial highlights increasing evidence that polyploidy and senescence can function together as a coordinated biological program. The authors focus on bladder umbrella cells, which form the barrier between urine and the bloodstream. In mice, these cells naturally become polyploid early in life and display markers of senescence across the lifespan. Rather than representing dysfunction, this state may help maintain tissue architecture, reinforce barrier integrity, and support resistance to environmental stress. In this context, polyploidy-induced senescence may act as a differentiation program that preserves organ structure. “Polyploidization and senescence may be interrelated stress responses, yet they have been studied mostly in isolation.” However, this protective mechanism may become unstable. Polyploidy-induced senescence depends on intact tumor suppressor pathways, including regulators such as p16. If these safeguards are lost through mutation, deletion, or epigenetic silencing, polyploid senescent cells may escape growth arrest. Re-entry into the cell cycle under these conditions may promote chromosomal instability and aneuploidy, increasing the likelihood of malignant transformation. The authors propose that a subset of bladder cancers may arise from polyploid umbrella cells that have bypassed this senescent barrier. The editorial also discusses implications for cancer therapy. Many anticancer treatments induce senescence and polyploidization in tumor cells. Although this approach can initially suppress proliferation, some polyploid cancer cells may later adapt, reduce their ploidy, and resume division, contributing to relapse and treatment resistance. Understanding how polyploidy and senescence interact may therefore inform therapeutic strategies. Overall, the authors emphasize the need to study polyploidy and senescence together rather than in isolation. Integrating ploidy assessment into large-scale mapping efforts of senescent cells may improve insight into aging biology, tumor initiation, and resistance to therapy. DOI: https://doi.org/10.18632/aging.206355 Corresponding author: Iman M. Al-Naggar - alnaggar@uchc.edu Introduction video - https://www.youtube.com/watch?v=3Cl-JoV-j0o https://www.Aging-US.com​​ MEDIA@IMPACTJOURNALS.COM

Mimic poison frogs are utterly amazing, famous for mimicking multiple different frog species, and like other dart frogs they demonstrate bi-parental care where both male and female frogs team up to look after the young. What we didn't know was how flexible these parental roles are - can females step in to move tadpoles when males start slacking, and what triggers them to do so? It turns out they can, but they don't always.  Become a Patreon: https://www.patreon.com/herphighlights Merch: https://www.redbubble.com/people/herphighlights/shop Full reference list available here: http://www.herphighlights.podbean.com Main Paper References: Moss JB, Winter BM, Westrick SE, Julkowski K, Podraza ME, Fischer EK. 2026. Partner cues and individual variation underlie sex-reversed parental care in poison frogs. Proceedings of the Royal Society B Biological Sciences 293:20252200. DOI: 10.1098/rspb.2025.2200. Other Mentioned Papers/Studies: Moss JB, Tumulty JP, Fischer EK. 2023 Evolution of acoustic signals associated with cooperative parental behavior in a poison frog. Proc. Natl Acad. Sci. USA 120, e2218956120. DOI: 10.1073/pnas.2218956120 Other Links/Mentions: Buy Pyro by Dallin Kohler: https://www.torreyhouse.org/pyro  Kohler, Dallin. 2025. Pyro: The Quest for a Beautifully Elusive Snake. 979-8-89092-022-5 Editing and Music: Intro/outro – Treehouse by Ed Nelson Species Bi-week theme – Michael Timothy Other Music – The Passion HiFi, https://www.thepassionhifi.com

Join the Behind the Knife Surgical Oncology Team as we discuss the PRADO and NADINA randomized control trials regarding neoadjuvant therapy in Stage III melanoma with macroscopic nodal disease!Hosts:Timothy Vreeland, MD, FACS (@vreelant) is an Assistant Professor of Surgery at the Uniformed Services University of the Health Sciences and Surgical Oncologist at Brooke Army Medical Center.Daniel Nelson, DO, FACS (@usarmydoc24) is Surgical Oncologist/HPB surgeon at Kaiser LAMC in Los Angeles.Lexy (Alexandra) Adams, MD, MPH (@lexyadams16) is a 2ndYear Surgical Oncology fellow at MD Anderson.Beth (Elizabeth) Barbera, MD (@elizcarpenter16) is a General Surgery physician in the United States Air Force station at RAF Lakenheath.Joe (Joseph) Broderick, MD, MA (@joebrod5) is a General Surgery research resident between his second and third year at Brooke Army Medical Center.Galen Gist, MD (@gistgalen) is a General Surgery research resident between his second and third year at Brooke Army Medical Center. Learning Objectives:-       Evaluate the role of Completion Lymph Node Dissection (CLND) in patients with positive sentinel lymph nodes, specifically citing the lack of melanoma-specific survival benefit vs. the improvement in regional disease control demonstrated in the MSLT-II trial.-       Determine the appropriate surgical excision margins for primary cutaneous melanoma, comparing the outcomes of 1 cm versus 2 cm margins as analyzed in the MINT trial (Lancet 2019).-       Analyze the impact of adjuvant systemic therapy (Anti-PD1/Immunotherapy) on recurrence-free survival in patients with resected high-risk Stage III melanoma.References:Reijers, I.L.M., Menzies, A.M., van Akkooi, A.C.J. et al. Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial. Nat Med 28, 1178–1188 (2022). https://doi.org/10.1038/s41591-022-01851-xChristian U. Blank et al. Neoadjuvant nivolumab plus ipilimumab versus adjuvant nivolumab in macroscopic, resectable stage III melanoma: The phase 3 NADINA trial.. J Clin Oncol 42, LBA2-LBA2(2024). DOI:10.1200/JCO.2024.42.17_suppl.LBA2*Sponsor Disclaimer: Visit goremedical.com/btkpod to learn more about GORE® SYNECOR Biomaterial, including supporting references and disclaimers for the presented content.  Refer to Instructions for Use at eifu.goremedical.com for a complete description of all applicable indications, warnings, precautions and contraindications for the markets where this product is available. Rx only Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.  If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium:General Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-audio-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-audio-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-audio-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-audio-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US

Authors Herng Lee Tan, MSc, and Judith Ju Ming Wong, MBBCh, BAO, and editorialist Vicent Modesto i Alapont, MD, PhD, join CHEST® Critical Care Podcast Moderator Dan Fein, MD, to discuss their research into the impact of mechanical power normalized to predicted body weight on outcomes in pediatric ARDS.  This episode is part of a new series exploring articles published in our open access journal CHEST Critical Care.  DOI: 10.1016/j.chstcc.2025.100162 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.  

BUFFALO, NY – February 16, 2026 – A new #commentary was #published in Volume 17 of Oncotarget on February 6, 2026, titled “Censorship in science: How publishing decisions could have shaped the perceived “general consensus” on COVID-19 vaccine safety and efficacy.” In this commentary, led by Panagis Polykretis of the “Allineare Sanità e Salute” Foundation and the Independent Medical Scientific Commission (CMSi) in Milan, along with colleagues, the authors document a two-year effort to publish a case report and literature review that raised concerns about possible links between mRNA COVID-19 vaccines and rare blood cancers. They argue that editorial decisions, rather than scientific merit, prevented the paper from being published, raising broader questions about transparency and bias in scientific publishing. The commentary outlines the submission history of a previously written case report describing a woman who developed acute lymphoblastic leukemia shortly after receiving an mRNA COVID-19 vaccine. Alongside the case, the original paper reviewed existing studies and regulatory findings related to hematological malignancies. Despite relying on published evidence and maintaining a cautious tone, the manuscript was rejected 16 times before eventually appearing in Oncotarget. According to the authors, most journals rejected the manuscript without external peer review. Three journals allowed it to proceed through peer review, and one journal accepted the paper twice before withdrawing its decision both times. The authors argue that such cancelations, particularly after positive peer review, suggest a pattern of editorial censorship that prioritizes conformity over open scientific debate. The commentary highlights examples of reviewer feedback and editorial statements that, according to the authors, misrepresented the content of the original case report. One rejection asserted that mRNA vaccines cannot cause cancer because they do not integrate into human DNA. The authors respond that this position is overly narrow and overlooks the complex, multifactorial nature of cancer development. They also cite peer-reviewed evidence of DNA contamination in vaccine samples and call for a more balanced and open discussion of these findings. Rather than claiming definitive proof of vaccine-related harm, the authors emphasize the importance of allowing controversial topics to be examined and discussed based on evidence. They argue that suppressing disagreement, even when grounded in published science, can influence public understanding and create the appearance of scientific consensus where meaningful disagreement exists. “This case raises serious concerns: if scientifically sound dissenting research faces systematic exclusion, the resulting literature becomes selectively curated, artificially constructing ‘consensus' while marginalizing legitimate scientific discourse.” The events described in the commentary raise concerns not only about a single case report but also about broader trends in academic publishing. If journal decisions are influenced by public health messaging rather than scientific reasoning, the authors argue that the scientific literature risks becoming selectively curated. They conclude by calling for institutional reform to ensure that editorial processes remain fair, evidence-based, and open to legitimate scientific debate. DOI - https://doi.org/10.18632/oncotarget.28829 Correspondence to - Panagis Polykretis - panagis.polykretis@gmail.com Abstract video - https://www.youtube.com/watch?v=255yn3sgx-0 To learn more about Oncotarget, please visit https://www.oncotarget.com. MEDIA@IMPACTJOURNALS.COM

Chinese conservationists have worked hard to protect the critically endangered Chinese alligator, creating new habitats for them after significant alterations made most of their Yangtze River home unsuitable. Thanks to the power of GPS technology, we now have some fascinating insights into how they are using the wetlands they are being reintroduced to, and it's mixed news. We follow that chat up with two new species of sand swimming skinks from Madagascar, and some big news from Tom about a brand new mammal. Become a Patreon: https://www.patreon.com/herphighlights Merch: https://www.redbubble.com/people/herphighlights/shop Full reference list available here: http://www.herphighlights.podbean.com Main Paper References: Li M, Sun K, Wang Z, Zhang C, Gao Y, Zhang S, Tu G, Wu X, Pan T. 2025. Extremely limited spatial and temporal utilization for wild Chinese alligator (Alligator sinensis). Biology Letters 21:20250513. DOI: 10.1098/rsbl.2025.0513. Species of the Bi-Week: Miralles A, Schmidt R, Rakotoarison A, Delaunay A, Freiwald A, Rahagalala NA, Rakotomanga S, Razafimanafo D, Ratsoavina FM, Crottini A, Raselimanana AP, Glaw F, Vences M. 2025. Integrative taxonomy of Madagascar's sand-swimming skinks (Scincidae: Voeltzkowia , Grandidierina) and preliminary evidence for an overlooked inland belt of white sand patches across the island's west. Zoological Journal of the Linnean Society 205:zlaf147. DOI: 10.1093/zoolinnean/zlaf147. Other Mentioned Papers/Studies: Sun K, Li M, Wang Z, Sun S, Yang J, Wu X, Pan T. 2025. Habitat Integrity Challenges for the Chinese Alligator Amid Land Occupation by Human: Pathways for Protection. Ecology and Evolution 15:e71113. DOI: 10.1002/ece3.71113. Other Links/Mentions: Wild London (~37 minutes in for Aesculapian snakes) - https://www.bbc.co.uk/programmes/m002hzg7  Editing and Music: Intro/outro – Treehouse by Ed Nelson Species Bi-week theme – Michael Timothy Other Music – The Passion HiFi, https://www.thepassionhifi.com

Why are compassion, kindness and humility critical to the care of patients in 2026? How can practitioners be taught these approaches and how does this 'triple gift' not only improve patient care but also professional interactions? Can this be taught? If so, what are the best ways? Professor Colin McMahon of Children's Health Ireland at Crumlin shares his deep insights into this important and oft-neglected aspect of being a caregiver. DOI: 10.1007/s00246-026-04161-yFollowing today's interview we also briefly speak with Professor Jack Rychik of Children's Hospital of Philadelphia about the upcoming CHOP 2026 meeting entitled "Cardiology 2026 - Together!". For those interested in possibly attending this meeting which begins on 2.28.26, take a look at the website below for more information:https://www.chop.edu/events/cardiology-2026

Show Notes & Links (Sources) Michigan CWD detected in Gladwin County (first time) — local reporting summarizing Michigan DNR/MSU lab confirmation. House Natural Resources Subcommittee on Federal Lands hearing (Feb 10, 2026) — committee hearing notice/details. DOI Secretarial Order 3447 (Jan 7, 2026) — DOI document + coverage/analysis. USFWS direct final rule on refuge regs; comment deadline Feb 17 — Federal Register entry + USFWS press release context. Lawsuit seeking a national gray wolf recovery plan (filed Feb 10, 2026) — regional reporting + lawsuit/press materials. Grizzly planning delay extension through Dec 18, 2026 — Mountain West reporting. Idaho Fish and Game: Deadwater ice jam out (Upper Salmon River) Feb 10, 2026 — IDFG update. 2026 fishing season regulation changes roundup (Yellowstone / Rockies) — Hatch Magazine coverage. California international wildlife trafficking disruption — California Governor's Office release + conservation outlet coverage. British Columbia 2026–2028 hunting/trapping proposals; lead shot discussion — BCWF explainer/position + related materials. B.C. caribou-related proposal coverage — regional reporting. Japan ivory market scrutiny statement (Feb 2, 2026) — NGO policy statement. Hunting Stories Links⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Want to be a guest?⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the Epigenetics Podcast, we talked with Srinjan Basu from Imperial College London to talk about his work on how chromatin architecture and epigenetic mechanisms orchestrate developmental gene expression programs. We begin by exploring Dr. Basu's early work at Harvard which involved pioneering Raman-based label-free imaging, allowing the study of chromatin dynamics in live tissue. Here, he tackles technical challenges faced in visualizing DNA interactions, emphasizing the shift from 2D to 3D analysis and the importance of real-time observation of chromatin behavior under various conditions. This segues into his groundbreaking research on single transcription factors interacting with chromatin, revealing subtle but significant changes in the dynamics of gene regulation. We transition into the complexities of chromatin architecture as Dr. Basu recounts his efforts in mapping the entire mouse genome in single pluripotent cells, unearthing unexpected heterogeneity among cells. This heterogeneity raises intriguing questions about its impact on cellular function, prompting ongoing investigations into chromatin dynamics and the role of remodeling complexes like NuRD in cell fate transitions. Dr. Basu elucidates how recent studies have begun to bridge the gaps in understanding how transcription factors and chromatin dynamics interact during cellular decisions, particularly emphasizing the influence of mechanical signals and the intrinsic properties of cells. His research underscores the idea that stem cells undergo a preparatory phase for differentiation, highlighting the critical balance of intrinsic and extrinsic factors that govern genetic expression and cellular outcomes. We also talk about Dr. Basu's current research trajectory, focusing on enhancing imaging techniques to study gene dynamics in tissue contexts relevant to developmental biology and disease states. He illustrates a vision for future projects that integrate advanced imaging tools to investigate transcription factor dynamics and chromatin interactions in live cells and embryos, furthering the understanding of decision-making processes in cellular contexts. References Stevens TJ, Lando D, Basu S, et al. 3D structures of individual mammalian genomes studied by single-cell Hi-C. Nature. 2017 Apr;544(7648):59-64. DOI: 10.1038/nature21429. PMID: 28289288; PMCID: PMC5385134. Basu S, Needham LM, Lando D, et al. FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells. Nature Communications. 2018 Jun;9(1):2520. DOI: 10.1038/s41467-018-04486-0. PMID: 29955052; PMCID: PMC6023872. Related Episodes Advanced Optical Imaging in 3D Nuclear Organisation (Lothar Schermelleh) Analysis of 3D Chromatin Structure Using Super-Resolution Imaging (Alistair Boettiger) Single-Molecule Imaging of the Epigenome (Efrat Shema) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

Send a textAnna Hamilton talks to us about the work of The Marjorie, Florida's independent reporting outlet dedicated to the critical intersection of social justice and the environment. Anna is the Co-Founder & Development Director for The Marjorie. She is a radio producer and oral historian whose work explores the cultures and environments of the American South. Anna has developed projects for the National Oceanic and Atmospheric Administration and the Southern Foodways Alliance, and reported for outlets including NPR and Reveal from the Center for Investigative Reporting. The Marjorie is not your source for breaking news. Instead, they specialize in telling in-depth stories about Florida's environment that consider human values as well as important historical and cultural contexts. The Marjorie was named for three of Florida's iconic Marjories: author Marjorie Kinnan Rawlings, conservationist Marjorie Harris Carr, and advocate Marjory Stoneman Douglas. The Marjorie has collaborated with members of the Stories-To-Live-By project through panel presentations and resource sharing. You can connect with Anna and The Marjorie at themarjorie.org. Resources mentioned in this episode:Egmont Key: A Seminole Story (https://stofthpo.com/wp-content/uploads/2022/08/Egmont-Key-Digital-book-web.pdf)To cite this episode:Persohn, L. (Host). (2026, Feb 12). A Stories-To-Live-By Conversation with Anna Hamilton from The Marjorie. (Season 6, No. 7) [Audio podcast episode]. In Classroom Caffeine Podcast series. https://www.classroomcaffeine.com/guests. DOI: 10.5240/AB4B-EC88-D5E0-A7FF-E805-GConnect with Classroom Caffeine at www.classroomcaffeine.com or on Instagram, Facebook, Twitter, and LinkedIn.

BUFFALO, NY – February 11, 2026 – A new #casereport was published in Volume 17 of Oncotarget on February 6, 2026, titled “Exploring the potential link between mRNA COVID-19 vaccinations and cancer: A case report with a review of haematopoietic malignancies with insights into pathogenic mechanisms.” In this report, led by first author Patrizia Gentilini along with corresponding author Panagis Polykretis from the “Allineare Sanità e Salute” Foundation and Independent Medical Scientific Commission (CMSi), Milano, an international team of researchers presented a detailed case involving a healthy, athletic woman who developed acute lymphoblastic leukemia and lymphoblastic lymphoma shortly after receiving her second dose of the Pfizer-BioNTech COVID-19 mRNA vaccine. The authors reviewed existing literature and discussed possible immune-related mechanisms that could connect mRNA vaccines to blood cancers, calling attention to the need for further investigation. The case report focuses on a 38-year-old woman who began experiencing immune-related symptoms the day after her second COVID-19 mRNA vaccine dose. Within months, she was diagnosed with an aggressive blood cancer affecting early-stage lymphocytes. While she initially achieved complete remission through chemotherapy, she later experienced a central nervous system relapse and underwent a stem cell transplant. The sequence of events raises questions about whether the vaccine-induced immune response may have contributed to disease onset or progression. To provide broader context, the authors reviewed several other reports describing similar cancer cases after COVID-19 vaccination. These included lymphomas, leukemias, and other haematopoietic disorders. In many cases, symptoms appeared shortly after vaccination. While these instances remain rare, the authors argue that the patterns merit closer study. They also discuss potential mechanisms, including immune suppression, increased inflammation, and vaccine-related interference with key cancer-protective proteins such as p53. One concern highlighted in the report involves lipid nanoparticles used to deliver the vaccine, which may circulate beyond the injection site and reach organs such as the bone marrow. The authors note that changes in immune signaling, antibody responses, and genetic material could, under certain conditions, create conditions favorable to cancer development in susceptible individuals. However, they emphasize that a definitive cause-and-effect relationship has not been established. “The carcinogenic risk associated with these technologies, which has long been known within the gene therapy field, represents an area of research that cannot be ignored, given the fundamental principle of medicine “primum non nocere” (first, do no harm).” Although the case does not prove that vaccination caused the cancer, it adds to a small body of evidence suggesting that immune disturbances from mRNA vaccines should be studied further. The authors emphasize the importance of continuing long-term safety monitoring as mRNA vaccine technologies are expanded to other uses. Understanding potential rare risks is essential for ensuring informed public health decisions while maintaining trust in vaccine programs. DOI - https://doi.org/10.18632/oncotarget.28827 Correspondence to - Panagis Polykretis - panagis.polykretis@gmail.com Abstract video - https://www.youtube.com/watch?v=OO-wewH7mEY To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

I am happy to welcome you to the inaugural podcast keynote! This is the official episode 400, so if you're listening to this in February there are 399 episodes to scroll beneath this one. I wanted to mark the 400th episode with something--- in episode 200 we had a town hall and it went really well. I am not sure where this will go on Laura's CV, but I am really happy she accepted the invitation to make something new and to be creative with me on this podcast! Dr. Laura Alfrey –is an associate professor at Monash University in Australia her research interests are in HPE and the ways which policy, professional learning and practice contribute to inclusive and educative experiences for everyone. Today she will share her innovative research in fitness testing…. But beyond publishing copious articles, getting cited hundreds of times a year for her work- Laura also serves the field by being on the Editorial Board for Curriculum Studies in HPE, Sport Education and Society, and the Journal of Teaching in Physical Education…AND MANY MORE!This podcast keynote is about fitness testing in PE, from an Australian lens, with a few notes about the American context, and some commentary by US based researchers as well. Here is a link to the video Laura showed: https://www.youtube.com/watch?v=VcH_IErqIXMThis is the article Chuck noted in his comment: Charles B. “Chuck” Corbin (2026)National Youth Fitness Tests and Awards: Dispelling Misconceptions andMisinformation, Journal of Physical Education, Recreation & Dance, 97:1,3-5, DOI: 10.1080/07303084.2025.2579444 To link to this article:https://doi.org/10.1080/07303084.2025.2579444

Unlock the future of farming with insights from one of America's leading agriculture champions. Aubrey Bettencourt, Chief of the NRCS, and Host Monte Bottens, talk through how innovative programs, voluntary practices, and market-driven solutions are transforming the ways farmers conserve resources, improve soil health, and remain resilient. Hear how the new, USDA outcomes-based regen pilot program is set to redefine the way we address resource concerns—making conservation efforts more practical, impactful, and sticky for farmers from coast to coast. Chief Bettencourt reveals the bold strategy behind the NRCS's reinvigorated mission: keeping farmers on the land and demonstrating that soil health and water management are not just buzzwords but vital pathways to economic and environmental security. We break down how existing programs like EQIP and CSP are being harnessed in innovative ways to accelerate regenerative practices without adding burdens—ensuring voluntary, flexible, and locally driven adoption. Aubrey shares her vision for a future where farmers are empowered, markets are aligned, and soil health becomes a shared goal—ultimately transforming agriculture into a resilient, sustainable engine for generations to come. Click to learn more about NRCS and the Regen Pilot Program: https://www.youtube.com/watch?v=FhuHrYrPXfM About NRCS​: https://www.nrcs.usda.gov/ ***About Our Guest: Aubrey J.D. Bettencourt serves as Chief of the Natural Resources Conservation Service (NRCS), the primary private lands conservation agency at the U.S. Department of Agriculture (USDA). NRCS helps producers, soil and water conservation districts, and other partners protect and conserve natural resources on private working lands while supporting American agricultural productivity throughout the United States. NRCS employees in the field work side-by-side with producers in every State and territory. Aubrey is a prominent leader in agriculture, water, and sustainability, most recently serving as the Global Director of Government Relations and External Affairs for Netafim, an Orbia Company. Prior to serving at Netafim, Aubrey was the President and Chief Executive Officer for the Almond Alliance, the national trade association advocating for American almond growers and processors. Prior to joining the Alliance, Aubrey served as the Sustainability Director for Western United Dairies, specifically leading initiatives in groundwater management. During the first Trump Administration, Aubrey worked with both the U.S. Department of the Interior (DOI) and USDA. As a Deputy Assistant Secretary with the DOI, she oversaw water and science policy. Prior to serving at DOI, Aubrey was the State Executive Director of USDA's Farm Service Agency in California where she directed the administration of farm commodity programs providing support, security, and emergency relief for producers throughout the state. Her work reflects her personal commitment to keep farmers farming through sound water policy, agricultural support, technology, and sustainable practices. This is supported by her family's farming roots in California's great Central Valley. Aubrey is a third-generation farmer at Bettencourt Farms in Kings County, California, alongside her father, mother, husband, daughter, and loyal farm dogs. Aubrey is an Eisenhower Agricultural Fellow and holds a degree in History from Westmont College in Santa Barbara, California.

This week we replay an episode from nearly 2 years ago about an editorial commentary from multiple congenital heart surgical leaders in the US. The topic of their expert opinion piece is the concept of public reporting of results and their 'amplification' through organizations such as US News and World Report, to name one. How has the use of the database from STS been sometimes misinterpreted through public reporting or ranking systems? What was the initial intent of the STS database and how does the present usage of these data differ from the initial intent? Do STS risk adjustment models capture all aspects of risk for patients undergoing surgery and how do deficiencies in this result in unfair 'rankings' of programs? Can we 'take control' of our data and interpret it more clearly and accurately for the public and reduce misusage or misinterpretation of the data? How can public reporting result in improved outcomes? How can 'gaming' of the system be reduced? Dr. Emile Bacha, Professor of Surgery at Columbia University shares his deep insights into a complex and challenging topic.DOI: 10.1016/j.jtcvs.2023.03.022

Den Abschluss der Vorlesung markierte eine Klausur, die ich, wie immer, selbst gern geschrieben hätte. Auch deshalb stelle ich sie im Stream kurz vor. Arbeitsauftrag und Material sind bei Zenodo (⁠https://doi.org/10.5281/zenodo.17370032⁠) hinterlegt. Präsentation (*.pdf): Alexander Lasch. 2025. Konstruktionsgrammatik. Zenodo. DOI: ⁠⁠⁠⁠⁠https://doi.org/10.5281/zenodo.17370032⁠⁠⁠⁠⁠. Videoaufzeichnungen: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://youtube.com/@AlexanderLasch⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Informationen & Material zu allen Vorlesungen: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://kurzelinks.de/fl7f⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Worksheet zu den Vorlesungen: ⁠⁠⁠⁠⁠⁠https://kurzlinks.de/WorksheetVorlesungen⁠⁠⁠⁠⁠⁠. Intro: "Reflections" von Scott Holmes (CC BY via ⁠⁠⁠⁠⁠⁠FMA⁠⁠⁠⁠⁠⁠).#Linguistik #OER #Sprache #Sprachwissenschaft #Grammatik #Konstruktionsgrammatik

Send us a textPharmacology & neurobiology of psychedelics & MDMA, focusing on isomers, sex-specific effects, and mechanisms in animal models. Not medical advice.TOPICS DISCUSSED:Biased agonism: Different drugs activate the same receptor (e.g., 5-HT2A) but trigger varied intracellular pathways, explaining why LSD is psychedelic while similar lisuride is not.Enantiomers & isomers: Mirror-image versions of drugs like MDMA (S and R forms) and LSD (four isomers) often produce distinct effects; only one LSD isomer is psychedelic, for example.MDMA isomer effects: S-MDMA induces stronger head twitches (psychedelic proxy) via serotonin release, and increases dendritic spines in male mice but not females; R-MDMA has somewhat different effects.Sex-specific drug responses: In mice, females show stronger psychedelic effects (head twitches) from psilocybin and DOI at the same dose, but males exhibit greater post-acute benefits like reduced opioid withdrawal.Psilocybin in opioid addiction models: A single dose reduces place preference for oxycodone and withdrawal symptoms in male mice more than females, with opposite spine density effects in reward-related brain areas.Mechanisms beyond 5-HT2A: Psychedelics involve other receptors like metabotropic glutamate receptors, forming dimers with 5-HT2A to enable dual signaling pathways; effects in subcortical regions like nucleus accumbens are 5-HT2A-independent.Clinical implications: Street MDMA may vary in S/R ratios, affecting experiences; clinical trials often use racemic mixtures without weight-adjusted dosing, potentially missing sex differences.ABOUT THE GUEST: Javier Gonzalez-Maeso, PhD is a professor of pharmacology and toxicology at Virginia Commonwealth University, with a PhD in medicine from Spain focused on G-protein coupled receptors and human brain studies in depression and addiction.RELATED EPISODE:M&M 230 | Psilocybin & MDMA: Inflammation, Stress & Brain-Body Communication | Michael WheelerSupport the showHealth Products by M&M Partners: SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

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We are the first generation of women who have actively been told not to have a period. Is this grounded in science or something else?Sources: https://hms.harvard.edu/news-events/publications-archive/brain/gut-brainRao, M., Gershon, M. The bowel and beyond: the enteric nervous system in neurological disorders. Nat Rev Gastroenterol Hepatol 13, 517–528 (2016). https://doi.org/10.1038/nrgastro.2016.107Holzer P, Schicho R, Holzer-Petsche U, Lippe IT. The gut as a neurological organ. Wien Klin Wochenschr. 2001 Sep 17;113(17-18):647-60. doi: 10.1002/j.2051-5545.2010.tb00298.xWinter, Gal, Hart, Robert A., Charlesworth, Richard P.G. and Sharpley, Christopher F.. "Gut microbiome and depression: what we know and what we need to know" Reviews in the Neurosciences, vol. 29, no. 6, 2018, pp. 629-643. https://doi.org/10.1515/revneuro-2017-0072doi:10.7759/cureus.9966https://ejhm.journals.ekb.eg/article_286004_84b20d7653f10cee5838cb13b8ec8333.pdfThe association between Diabetes mellitus and DepressionSV Bădescu,* C Tătaru,** L Kobylinska,* EL Georgescu,* DM Zahiu,* AM Zăgrean,* and L Zăgrean*The bidirectional interaction between antidepressants and the gut microbiota: are there implications for treatment response?Borgiani, Gianlucaa,*; Possidente, Chiaraa,b,c,d,*; Fabbri, Chiaraa,e; Oliva, Vincenzoa,b,c,d; Bloemendaal, Mirjamf,g; Arias Vasquez, Alejandrof,h; Dinan, Ted G.i,j; Vieta, Eduardb,c,d,k; Menchetti, Marcoa; De Ronchi, Dianaa; Serretti, Alessandroa,l; Fanelli, Giuseppea,hAuthor InformationInternational Clinical Psychopharmacology ():10.1097/YIC.0000000000000533, February 06, 2024. | DOI: 10.1097/YIC.0000000000000533doi: 10.1038/s41398-019-0466-xAntidepressants affect gut microbiota and Ruminococcus flavefaciens is able to abolish their effects on depressive-like behavior

Hemang Yadav, MBBS, joins CHEST® Journal Podcast Moderator Alice Gallo De Moraes, MD, FCCP, to discuss his research into the magnitude and determinants of diffusing capacity for carbon monoxide intersession variability in routine clinical practice and evidence-based thresholds that can guide interpretation of serial measurements. DOI: 10.1016/j.chest.2025.09.006 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.  

What's the episode about? In this episode, hear Nina Vaswani on young men and grief during in imprisonment, childhood bereavement, masculinities and grief, trauma informed practice, comics for education and research, disenfranchised grief, grieving a death you have caused, and public health responses to grief Who is Nina? Nina is Senior Research Fellow at the Children and Young People's Centre for Justice, University of Strathclyde.  Her key research interests are the experience and impact of loss, bereavement and trauma in young people and how these experiences interface and shape contact with the justicesystem.  Of particular interest is the overrepresentation of young men in justice-settings, and how their exposure to loss, bereavement and trauma might shape their developing masculinities identities, behaviours and outcomes. As a result, she is also interested in institutional and organisational responses to trauma, and the realities of trauma-informed approaches in practice.  Nina was also the PI on Men Minds, a coproduced research project exploring masculinities and mental health with marginalised young men.Resources When People Die Men Minds comic, whichopens with a story of bereavement in prison  The prevalence study isopen access and is available here. How do I cite the episode in my research and reading lists?To cite this episode, you can use the following citation: Vaswani, N. (2026) Interview on The Death Studies Podcast hosted by Michael-Fox, B. and Visser, R. Published 2 January 2026. Available at: www.thedeathstudiespodcast.com, DOI: 10.6084/m9.figshare.31224109 

Meditation-Induced Changes in High-Frequency Heart Rate Variability Predict Smoking OutcomesDr. Jud explores a pivotal study linking mindfulness meditation and heart rate variability (HRV) to smoking cessation success. This episode delves into how acute changes in high-frequency HRV during meditation correlate with reduced cigarette consumption over time. By examining the physiological underpinnings of self-regulation and addiction, Dr. Jud highlights how HRV may serve as a biomarker to tailor interventions. Tune in to uncover how meditation can reshape the body's stress response and support lasting behavioral change.Reference:Libby DJ, Worhunsky PD, Pilver CE, Brewer JA. Meditation-induced changes in high-frequency heart rate variability predict smoking outcomes. Frontiers in Human Neuroscience. 2012;6:54. DOI: 10.3389/fnhum.2012.00054Let's connect on Instagram

We have covered the subject of whether to include the decidual (innermost) layer when closing the uterine incision during cesarean section (CS) on at least 2 episodes. The most recent was in September 2025, when we focused on a published (September 2025) systematic review and meta-analysis from the Green Journal. Back then, we compared those new findings to our prior episode from 2023 on the same matter. Well, we are back at it again with the same subject as there is a new EXPERT REVIEW from the AJOG on hysterotomy closure technique which just came out January 2026. What did these authors conclude? There are also some controversial suggestions made by the authors. Listen in for details. 1. Antoine C, Meyer JA, Silverstein J, Buldo-Licciardi J, Lyu C, Timor-Tritsch IE. Endometrium-Free Closure Technique During Cesarean Delivery for Reducing the Risk of Niche Formation and Placenta Accreta Spectrum Disorders. Obstet Gynecol. 2025 Jun 1;145(6):674-682. doi: 10.1097/AOG.0000000000005813. Epub 2025 Jan 9. PMID: 39787602. 2. Gialdini, Celina et al.Evidence-based surgical procedures to optimize caesarean outcomes: an overview of systematic reviews. eClinicalMedicine- Lancet (June 2024), Volume 72, 102632 3. Dahlke, Joshua D. MD; Mendez-Figueroa, Hector MD; Maggio, Lindsay MD, MPH; Sperling, Jeffrey D. MD, MS; Chauhan, Suneet P. MD, Hon DSc; Rouse, Dwight J. MD. The Case for Standardizing Cesarean Delivery Technique: Seeing the Forest for the Trees. Obstetrics & Gynecology 136(5):p 972-980, November 2020. | DOI: 10.1097/AOG.0000000000004120 4. Antoine C, Timor-Tritsch IE, Bujold E, Young BK, Reece EA. Endometrium-free closure technique for hysterotomy incision at cesarean delivery. Am J Obstet Gynecol. 2026 Jan;233(6S):S103-S114. doi: 10.1016/j.ajog.2025.07.009. PMID: 41485813.

In this episode of the Epigenetics Podcast, we talked with Peggy Farnham from the Keck School of Medicine at USC about her work on establishing the ChIP Method in mammalian cells. In this episode, we dive into the relationship between transcription factors, chromatin dynamics, and gene expression with Professor Peggy Farnham from the Keck School of Medicine at USC. Professor Farnham shares her profound insights into how her groundbreaking research has reshaped our understanding of gene regulation and its implications in cancer. We explore how she has been a pioneer in mapping the genome-wide landscape of regulatory proteins, illuminating the molecular logic behind transcriptional control and its disruption in cancer biology. The interview starts with her instrumental role in adapting chromatin immunoprecipitation (ChIP) technology from yeast to human cells. Professor Farnham reflects on the technical challenges she faced during this transition, such as the quest for visibility of signals in mammalian systems. Her ability to innovate and troubleshoot challenges led to significant advancements in techniques that allow for the rapid identification of transcription factor binding sites, fundamentally changing the landscape of epigenetic research. As the discussion progresses, we learn about Professor Farnham's active involvement in the ENCODE project, where she contributed to high-resolution mapping of transcription factors and regulatory elements in human cells. She articulates her appreciation for collaborative efforts in science, highlighting how working within a consortium harnesses the collective expertise of diverse research groups. This collaboration not only bolstered the credibility of the data produced but also propelled the field forward in understanding the complexity of gene regulation. Through her participation in various projects, such as the Psyc-ENCODE consortium and the Roadmap Epigenome Mapping Consortium, Professor Farnham shares insights into her investigation of epigenetic variations, particularly in relation to complex disorders like schizophrenia. Her findings underscore the nuances of enhancer variability among individuals and the implications for understanding disease mechanisms, thereby advancing our knowledge of genetic regulation and its contributions to diverse biological outcomes. Moreover, the episode highlights Professor Farnham's reflective understanding of emerging technologies in the field. She discusses the evolution of methods that allow researchers to investigate gene regulation at single-cell resolution, recognizing the significant implications these innovations have for our comprehension of cellular differentiation and the transcriptional landscape. References Weinmann AS, Bartley SM, Zhang T, Zhang MQ, Farnham PJ. Use of chromatin immunoprecipitation to clone novel E2F target promoters. Molecular and Cellular Biology. 2001 Oct;21(20):6820-6832. DOI: 10.1128/mcb.21.20.6820-6832.2001. PMID: 11564866; PMCID: PMC99859. Wells J, Farnham PJ. Characterizing transcription factor binding sites using formaldehyde crosslinking and immunoprecipitation. Methods (San Diego, Calif.). 2002 Jan;26(1):48-56. DOI: 10.1016/s1046-2023(02)00007-5. PMID: 12054904. Rhie SK, Schreiner S, Witt H, et al. Using 3D epigenomic maps of primary olfactory neuronal cells from living individuals to understand gene regulation. Science Advances. 2018 Dec;4(12):eaav8550. DOI: 10.1126/sciadv.aav8550. PMID: 30555922; PMCID: PMC6292713. Tak YG, Hung Y, Yao L, et al. Effects on the transcriptome upon deletion of a distal element cannot be predicted by the size of the H3K27Ac peak in human cells. Nucleic Acids Research. 2016 May;44(9):4123-4133. DOI: 10.1093/nar/gkv1530. PMID: 26743005; PMCID: PMC4872074. Related Episodes The Effect of lncRNAs on Chromatin and Gene Regulation (John Rinn) CpG Islands, DNA Methylation, and Disease (Sir Adrian Bird) The Future of Protein–DNA Mapping (Mitch Guttman) MLL Proteins in Mixed-Lineage Leukemia (Yali Dou) Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

Nutritional rickets is caused by a vitamin D deficiency, and people figured out two ways to treat it before we even knew what vitamin D was. Research: “Oldest UK case of rickets in Neolithic Tiree skeleton.” 9/10/2015. https://www.bbc.com/news/uk-scotland-glasgow-west-34208976 Carpenter, Kenneth J. “Harriette Chick and the Problem of Rickets.” The Journal of Nutrition, Volume 138, Issue 5, 827 – 832 Chesney, Russell W. “New thoughts concerning the epidemic of rickets: was the role of alum overlooked?.” Pediatric Nephrology. (2012) 27:3–6. DOI 10.1007/s00467-011-2004-9. Craig, Wallace and Morris Belkin. “The Prevention and Cure of Rickets.” The Scientific Monthly , May, 1925, Vol. 20, No. 5 (May, 1925). Via JSTOR. https://www.jstor.org/stable/7260 Davidson, Tish. "Rickets." The Gale Encyclopedia of Medicine, edited by Jacqueline L. Longe, 6th ed., vol. 7, Gale, 2020, pp. 4485-4487. Gale OneFile: Health and Medicine, link.gale.com/apps/doc/CX7986601644/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=811f7e02. Accessed 7 Jan. 2026. Friedman, Aaron. “A brief history of rickets.” Pediatric Nephrology (2020) 35:1835–1841. https://doi.org/10.1007/s00467-019-04366-9 Hawkes, Colin P, and Michael A Levine. “A painting of the Christ Child with bowed legs: Rickets in the Renaissance.” American journal of medical genetics. Part C, Seminars in medical genetics vol. 187,2 (2021): 216-218. doi:10.1002/ajmg.c.31894 Ihde, Aaron J. “Studies on the History of Rickets. I: Recognition of Rickets as a Deficiency Disease.” Pharmacy in History, 1974, Vol. 16, No. 3 (1974). https://www.jstor.org/stable/41108858 Ihde, Aaron J. “Studies on the History of Rickets. II : The Roles of Cod Liver Oil and Light.” Pharmacy in History, 1975, Vol. 17, No. 1 (1975). https://www.jstor.org/stable/41108885 Newton, Gil. “Diagnosing Rickets in Early Modern England: Statistical Evidence and Social Response.” Social History of Medicine Vol. 35, No. 2 pp. 566–588. https://academic.oup.com/shm/article/35/2/566/6381535 O'Riordan, Jeffrey L H, and Olav L M Bijvoet. “Rickets before the discovery of vitamin D.” BoneKEy reports vol. 3 478. 8 Jan. 2014, doi:10.1038/bonekey.2013.212. Palm, T. “Etiology of Rickets.” Br Med J 1888; 2 doi: https://doi.org/10.1136/bmj.2.1457.1247 (Published 01 December 1888) Rajakumar, Kumaravel and Stephen B. Thomas. “Reemerging Nutritional Rickets: A Historical Perspective.” Arch Pediatr Adolesc Med. Published Online: April 2005 2005;159;(4):335-341. doi:10.1001/archpedi.159.4.335 Swinburne, Layinka M. “Rickets and the Fairfax family receipt books.” Journal of the Royal Society of Medicine. Vol. 99. August 2006. Tait, H. P.. “Daniel Whistler and His Contribution to Pædiatrics.” Edinburgh Medical Journal vol. 53,6 (1946): 325–330. Warren, Christian. “No Magic Bolus: What the History of Rickets and Vitamin D Can Teach Us About Setting Standards.” Journal of Adolescent Health. 66 (2020) 379e380. https://www.jahonline.org/article/S1054-139X(20)30038-0/pdf Wheeler, Benjamin J et al. “A Brief History of Nutritional Rickets.” Frontiers in endocrinology vol. 10 795. 14 Nov. 2019, doi:10.3389/fendo.2019.00795 World Health Organization. “The Magnitude and Distribution of Nutritoinal Rickets: Disease Burden in Infants, Children, and Adolescents.” 2019. Via JSTOR. https://www.jstor.org/stable/resrep27899.7 Zhang, M., Shen, F., Petryk, A., Tang, J., Chen, X., & Sergi, C. (2016). “English Disease”: Historical Notes on Rickets, the Bone–Lung Link and Child Neglect Issues. Nutrients, 8(11), 722. https://doi.org/10.3390/nu8110722 See omnystudio.com/listener for privacy information.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-469 Overview: Tune in to hear how self-collected vaginal human papillomavirus (HPV) testing has potential to expand access to cervical cancer screening and reduce barriers for your patients. This episode reviews cervical cancer screening guidelines, follow-up recommendations, and how to consider offering self-collection as an option to increase screening rates and improve preventive care in your practice. Episode resource links: CA CancerJClin.2026;e70041. DOI:10.3322/caac.70041 US Food and Drug Administration (FDA). Device Classification Under Section 513(f)(2)(De Novo). Device for home collection and transport of vaginal specimens by lay users for use in an approved HPV molecular assay. FDA; 2025. FranklySpeaking@pri-med.com  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-469 Overview: Tune in to hear how self-collected vaginal human papillomavirus (HPV) testing has potential to expand access to cervical cancer screening and reduce barriers for your patients. This episode reviews cervical cancer screening guidelines, follow-up recommendations, and how to consider offering self-collection as an option to increase screening rates and improve preventive care in your practice. Episode resource links: CA CancerJClin.2026;e70041. DOI:10.3322/caac.70041 US Food and Drug Administration (FDA). Device Classification Under Section 513(f)(2)(De Novo). Device for home collection and transport of vaginal specimens by lay users for use in an approved HPV molecular assay. FDA; 2025. FranklySpeaking@pri-med.com  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Back in March of 2025, the green journal (obstetrics andgynecology) published A systematic review and meta-analysis on 2 medications (non-hormonal) and their efficacy in menopausal hot flash relief period these medications were Fezolinetant and Elinzanetant. However, the editors have just recently released an “Expression of Concern” about this review. Listen in for details. 1.     Menegaz de Almeida, Artur MS; Oliveira, PalomaMS; Lopes, Lucca MD; Leite, Marianna MS; Morbach, Victória MS; Alves Kelly,Francinny MD; Barros, Ítalo MS; Aquino de Moraes, Francisco Cezar MS;Prevedello, Alexandra MD. Fezolinetant and Elinzanetant Therapy for MenopausalWomen Experiencing Vasomotor Symptoms: A Systematic Review and Meta-analysis.Obstetrics & Gynecology 145(3):p 253-261, March 2025. | DOI:10.1097/AOG.00000000000058122.     Expression of Concern: Fezolinetant andElinzanetant Therapy for Menopausal Women Experiencing Vasomotor Symptoms: ASystematic Review and Meta-Analysis. Obstetrics & Gynecology():10.1097/AOG.0000000000006180, January 16, 2026. | DOI: 10.1097/AOG.0000000000006180

Smartband-Based Smoking Detection and Real-Time Brief Mindfulness Intervention: Findings from a Feasibility Clinical TrialIn this episode, Dr. Jud examines the groundbreaking results from a feasibility trial exploring the use of smartbands for smoking cessation. This innovative study showcases how wearable technology can detect smoking events in real time and deliver brief mindfulness interventions to address cravings. Dr. Jud discusses the study's design, key findings, and their implications for the future of digital health interventions. Learn how the integration of real-time behavioral data with mindfulness-based techniques holds the potential to transform smoking cessation efforts globally.Reference:Horvath M, Pittman B, O'Malley SS, Grutman A, Khan N, Gueorguieva R, Brewer JA, Garrison KA. Smartband-Based Smoking Detection and Real-Time Brief Mindfulness Intervention: Findings from a Feasibility Clinical Trial. Annals of Medicine. 2024;56(1):2352803. DOI: 10.1080/07853890.2024.2352803Let's connect on Instagram

Ursodiol (ursodeoxycholic acid) is a prescription bile acid medication used to dissolve cholesterol gallstones, prevent gallstones during rapid weight loss, and treat liver diseases like primary biliary cholangitis (PBC) by reducing toxic bile acids and cholesterol production. It works by changing bile composition, making it less saturated with cholesterol, and is available as oral medication. Of course, it is also the foundational medication for treatment of diagnosed Intrahepatic Cholestasis of Pregnancy (ICP). Does this medication reduce adverse perinatal outcomes? In this episode, we will review a new study from the Green Journal, which will be out in February 2026, examining the recurrence risk for ICP using data from NY. In a patient with prior history of ICP, is there any guidance on monitoring of serum bile acids in the subsequent pregnancy before symptoms develop? We will explain. PLUS we will review the data on whether Ursodiol may hold promise in recurrence prevention or in reduction of adverse outcomes once the condition is diagnosed. Listen in for details. 1. 2019: Chappell LC, Bell JL, Smith A, Linsell L, Juszczak E, Dixon PH, Chambers J, Hunter R, Dorling J, Williamson C, Thornton JG; PITCHES study group. Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial. Lancet. 2019 Sep 7;394(10201):849-860. doi: 10.1016/S0140-6736(19)31270-X. Epub 2019 Aug 1. PMID: 31378395; PMCID: PMC6739598. https://pubmed.ncbi.nlm.nih.gov/31378395/2. February 08, 2025: Rahim, Mussarat N et al. Pregnancy and the liver. The Lancet. 2021; Volume 405, Issue 10477, 498 – 513 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02351-1/fulltext3. SMFM CS 53; 20214. Rosenberg, Henri M. MD; Sarker, Minhazur R. MD; Ramos, Gladys A. MD; Bianco, Angela MD; Ferrara, Lauren MD; DeBolt, Chelsea A. MD. Intrahepatic Cholestasis of Pregnancy Recurrence in a Subsequent Pregnancy. Obstetrics & Gynecology 147(2):p 239-241, February 2026. | DOI: 10.1097/AOG.0000000000006033 https://journals.lww.com/greenjournal/fulltext/2026/02000/intrahepatic_cholestasis_of_pregnancy_recurrence.13.aspx5. Ovadia C, Sajous J, Seed PT et al. Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis. Lancet Gastroenterol Hepatol. 2021 Jul;6(7):547-558. doi: 10.1016/S2468-1253(21)00074-1. Epub 2021 Apr 27. PMID: 33915090; PMCID: PMC8192305.6. EASL Clinical Practice Guidelines on the management of liver diseases in pregnancy. European Association for the Study of the Liver; 2023

Exploramos los hallazgos más recientes sobre compresiones manuales versus compresiones mecánicas en la reanimación cardiopulmonar. ¿Qué opción ofrece mejores resultados en pacientes con paro cardíaco? ¿Qué deben saber los proveedores de ACLS hoy?

Discussion of things literally or figuratively unearthed in the last quarter of 2025 continues. It begins with potpourri then covers tools, Neanderthals, edibles and potables, art, shipwrecks, medical finds, and repatriations. Research: Abdallah, Hanna. “Famous Easter Island statues were created without centralized management.” PLOS. Via EurekAlert. 11/26/2025. https://www.eurekalert.org/news-releases/1106805 Abdallah, Hannah. “Early humans butchered elephants using small tools and made big tools from their bones.” PLOS. Via EurekAlert. 10/8/2025. https://www.eurekalert.org/news-releases/1100481 Abdallah, Hannah. “Researchers uncover clues to mysterious origin of famous Hjortspring boat.” EurekAlert. 10/12/2025. https://www.eurekalert.org/news-releases/1108323 Archaeology Magazine. “Medieval Hoard of Silver and Pearls Discovered in Sweden.” https://archaeology.org/news/2025/10/14/medieval-hoard-of-silver-and-pearls-discovered-in-sweden/ Archaeology Magazine. “Possible Trepanation Tool Unearthed in Poland.” 11/13/2025. https://archaeology.org/news/2025/11/13/possible-trepanation-tool-unearthed-in-poland/ Arkeologerna. “Rare 5,000-year-old dog burial unearthed in Sweden.” 12/15/2025. https://news.cision.com/se/arkeologerna/r/rare-5-000-year-old-dog-burial-unearthed-in-sweden,c4282014 Arnold, Paul. “Ancient ochre crayons from Crimea reveal Neanderthals engaged in symbolic behaviors.” Phys.org. 10/30/2025. https://phys.org/news/2025-10-ancient-ochre-crayons-crimea-reveal.html Arnold, Paul. “Dating a North American rock art tradition that lasted 175 generations.” Phys.org. 11/28/2025. https://phys.org/news/2025-11-dating-north-american-art-tradition.html Bassi, Margherita. “A Single Gene Could Have Contributed to Neanderthals’ Extinction, Study Suggests.” Smithsonian. 10/30/2025. https://www.smithsonianmag.com/smart-news/a-neanderthal-gene-variant-related-to-red-blood-cells-may-have-contributed-to-their-extinction-180987586/ Benjamin Pohl, Chewing over the Norman Conquest: the Bayeux Tapestry as monastic mealtime reading, Historical Research, 2025;, htaf029, https://doi.org/10.1093/hisres/htaf029 Benzine, Vittoria. “Decoded Hieroglyphics Reveal Female Ruler of Ancient Maya City.” ArtNet. 10/27/2025. https://news.artnet.com/art-world/foundation-stone-maya-coba-woman-ruler-2704521 Berdugo, Sophie. “Easter Island statues may have 'walked' thanks to 'pendulum dynamics' and with as few as 15 people, study finds.” LiveScience. 10/19/2025. https://www.livescience.com/archaeology/easter-island-statues-may-have-walked-thanks-to-pendulum-dynamics-and-with-as-few-as-15-people-study-finds Billing, Lotte. “Fingerprint of ancient seafarer found on Scandinavia’s oldest plank boat.” EurekAlert. 10/12/2025. https://www.eurekalert.org/news-releases/1109361 Brhel, John. “Rats played major role in Easter Island’s deforestation, study reveals.” EurekAlert. 11/17/2025. https://www.eurekalert.org/news-releases/1106361 Caldwell, Elizabeth. “9 more individuals unearthed at Oaklawn could be 1921 Tulsa Race Massacre victims.” Tulsa Public Radio. 11/6/2025. https://www.publicradiotulsa.org/local-regional/2025-11-06/9-more-individuals-unearthed-at-oaklawn-could-be-1921-tulsa-race-massacre-victims Clark, Gaby. “Bayeux Tapestry could have been originally designed as mealtime reading for medieval monks.” Phys.org. 12/15/2025. https://phys.org/news/2025-12-bayeux-tapestry-mealtime-medieval-monks.html#google_vignette Cohen, Alina. “Ancient Olive Oil Processing Complex Unearthed in Tunisia.” Artnet. 11/21/2025. https://news.artnet.com/art-world/ancient-olive-oil-complex-tunisia-2717795 Cohen, Alina. “MFA Boston Restores Ownership of Historic Works by Enslaved Artist.” ArtNet. 10/30/2025. https://news.artnet.com/art-world/mfa-boston-david-drake-jars-restitution-2706594 Fergusson, Rachel. “First DNA evidence of Black Death in Edinburgh discovered on teeth of excavated teenage skeleton.” The Scotsman. 11/5/2025. https://www.scotsman.com/news/first-dna-evidence-black-death-edinburgh-discovered-teeth-excavated-teenage-skeleton-5387741 Folorunso, Caleb et al. “MOWAA Archaeology Project: Enhancing Understanding of Benin City’s Historic Urban Development and Heritage through Pre-Construction Archaeology.” Antiquity (2025): 1–10. Web. Griffith University. “Rare stone tool cache tells story of trade and ingenuity.” 12/2/2025. https://news.griffith.edu.au/2025/12/02/rare-stone-tool-cache-tells-story-of-trade-and-ingenuity/ Han, Yu et al. “The late arrival of domestic cats in China via the Silk Road after 3,500 years of human-leopard cat commensalism.” Cell Genomics, Volume 0, Issue 0, 101099. https://www.cell.com/cell-genomics/fulltext/S2666-979X(25)00355-6 Hashemi, Sara. “A Volcanic Eruption in 1345 May Have Triggered a Chain of Events That Brought the Black Death to Europe.” Smithsonian. 12/8/2025. https://www.smithsonianmag.com/smart-news/a-volcanic-eruption-in-1345-may-have-triggered-a-chain-of-events-taht-brought-the-black-death-to-europe-180987803/ Hjortkjær, Simon Thinggaard. “Mysterious signs on Teotihuacan murals may reveal an early form of Uto-Aztecan language.” PhysOrg. 10/6/2025. https://phys.org/news/2025-10-mysterious-teotihuacan-murals-reveal-early.html Institut Pasteur. “Study suggests two unsuspected pathogens struck Napoleon's army during the retreat from Russia in 1812.” Via EurekAlert. 10/24/2025. https://www.eurekalert.org/news-releases/1102613 Jones, Sam. “Shells found in Spain could be among oldest known musical instruments.” The Guardian. 12/2/2025. https://www.theguardian.com/science/2025/dec/02/neolithic-conch-like-shell-spain-catalonia-discovery-musical-instruments Kasal, Krystal. “Pahon Cave provides a look into 5,000 years of surprisingly stable Stone Age tool use.” Phys.org. 12/16/2025. https://phys.org/news/2025-12-pahon-cave-years-stable-stone.html Kristiansen, Nina. “Eight pages bound in furry seal skin may be Norway's oldest book.” Science Norway. 11/3/2025. https://www.sciencenorway.no/cultural-history-culture-history/eight-pages-bound-in-furry-seal-skin-may-be-norways-oldest-book/2571496 Kuta, Sarah. “109-Year-Old Messages in a Bottle Written by Soldiers Heading to Fight in World War I Discovered on Australian Beach.” Smithsonian. 11/6/2025. https://www.smithsonianmag.com/smart-news/109-year-old-messages-in-a-bottle-written-by-soldiers-heading-to-fight-in-world-war-i-discovered-on-australian-beach-180987649/ Kuta, Sarah. “A Storm Battered Western Alaska, Scattering Thousands of Indigenous Artifacts Across the Sand.” Smithsonian. 10/31/2025. https://www.smithsonianmag.com/smart-news/a-storm-battered-western-alaska-scattering-thousands-of-indigenous-artifacts-across-the-sand-180987606/ Kuta, Sarah. “Archaeologists Unearth More Than 100 Projectiles From an Iconic Battlefield in Scotland.” Smithsonian. 11/5/2025. https://www.smithsonianmag.com/smart-news/archaeologists-unearth-more-than-100-projectiles-from-an-iconic-battlefield-in-scotland-180987641/ Kuta, Sarah. “Hundreds of Mysterious Victorian-Era Shoes Are Washing Up on a Beach in Wales. Nobody Knows Where They Came From.” Smithsonian. 1/5/2026. https://www.smithsonianmag.com/smart-news/hundreds-of-mysterious-victorian-era-shoes-are-washing-up-on-a-beach-in-wales-nobody-knows-where-they-came-from-180987943/ Lawson-Tancred, Jo. “Golden ‘Tudor Heart’ Necklace Sheds New Light on Henry VIII’s First Marriage.” Artnet. 10/14/2025. https://news.artnet.com/art-world/tudor-heart-pendant-british-museum-fundraiser-2699544 Lawson-Tancred, Jo. “Long-Overlooked Black Veteran Identified in Rare 19th-Century Portrait.” ArtNet. 10/27/2025. https://news.artnet.com/art-world/black-veteran-thomas-phillips-portrait-identified-2704721 Lipo CP, Hunt TL, Pakarati G, Pingel T, Simmons N, Heard K, et al. (2025) Megalithic statue (moai) production on Rapa Nui (Easter Island, Chile). PLoS One 20(11): e0336251. https://doi.org/10.1371/journal.pone.0336251 Lipo, Carl P. and Terry L. Hunt. “The walking moai hypothesis: Archaeological evidence, experimental validation, and response to critics.” Journal of Archaeological Science. Volume 183, November 2025, 106383. https://www.sciencedirect.com/science/article/abs/pii/S0305440325002328 Lock, Lisa. “Pre-construction archaeology reveals Benin City's historic urban development and heritage.” 10/29/2025. https://phys.org/news/2025-10-pre-archaeology-reveals-benin-city.html#google_vignette Lock, Lisa. “Pre-construction archaeology reveals Benin City's historic urban development and heritage.” Antiquity. Via PhysOrg. 10/29/2025. https://phys.org/news/2025-10-pre-archaeology-reveals-benin-city.html#google_vignette Lynley A. Wallis et al, An exceptional assemblage of archaeological plant fibres from Windmill Way, southeast Cape York Peninsula, Australian Archaeology (2025). DOI: 10.1080/03122417.2025.2574127 Lyon, Devyn. “Oaklawn Cemetery excavation brings investigators closer to identifying Tulsa Race Massacre victims.” Fox 23. 11/6/2025. https://www.fox23.com/news/oaklawn-cemetery-excavation-brings-investigators-closer-to-identifying-tulsa-race-massacre-victims/article_67c3a6b7-2acc-44cb-93ce-3d3d0c288eca.html Marquard, Bryan. “Bob Shumway, last known survivor of the deadly Cocoanut Grove nightclub fire, dies at 101.” 11/12/2025. https://www.bostonglobe.com/2025/11/12/metro/bob-shumway-101-dies-was-last-known-cocoanut-grove-fire-survivor/?event=event12 Marta Osypińska et al, A centurion's monkey? Companion animals for the social elite in an Egyptian port on the fringes of the Roman Empire in the 1st and 2nd c. CE, Journal of Roman Archaeology (2025). DOI: 10.1017/s1047759425100445 Merrington, Andrew. “Extensive dog diversity millennia before modern breeding practices.” University of Exeter. 11/13/2025. https://news.exeter.ac.uk/faculty-of-humanities-arts-and-social-sciences/archaeology-and-history/extensive-dog-diversity-millennia-before-modern-breeding-practices/ Morris, Steven. “Linguists start compiling first ever complete dictionary of ancient Celtic.” The Guardian. 12/8/2025. https://www.theguardian.com/science/2025/dec/08/linguists-start-compiling-first-ever-complete-dictionary-of-ancient-celtic Museum of Fine Arts, Boston. “Museum of Fine Arts, Boston, Resolves Ownership of Works by Enslaved Artist David Drake.” 10/29/2025. https://www.mfa.org/press-release/david-drake-ownership-resolution Narcity. “Niagara has a 107-year-old shipwreck lodged above the Falls and it just moved.” https://www.narcity.com/niagara-falls-shipwreck-iron-scow-moved-closer-to-the-falls Newcomb, Tim. “A 76-Year-Old Man Went On a Hike—and Stumbled Upon a 1,500-Year Old Trap.” Popular Mechanics. 11/21/2025. https://www.popularmechanics.com/science/archaeology/a69441460/reindeer-trap/ Nordin, Gunilla. “Ancient wolves on remote Baltic Sea island reveal link to prehistoric humans.” Stockholm University. Via EurekAlert. 11/24/2025. https://www.eurekalert.org/news-releases/1106807 Oster, Sandee. “DNA confirms modern Bo people are descendants of ancient Hanging Coffin culture.” Phys.org. 12/6/2025. https://phys.org/news/2025-12-dna-modern-bo-people-descendants.html Oster, Sandee. “Rare disease possibly identified in 12th century child's skeletal remains.” PhysOrg. 10/10/2025. https://phys.org/news/2025-10-rare-disease-possibly-12th-century.html Osuh, Chris and Geneva Abdul. “Lost grave of daughter of Black abolitionist Olaudah Equiano found by A-level student.” The Guardian. 11/1/2025. https://www.theguardian.com/uk-news/2025/nov/01/lost-grave-daughter-black-abolitionist-olaudah-equiano-found-by-a-level-student Silvia Albizuri et al, The oldest mule in the western Mediterranean. The case of the Early Iron Age in Hort d'en Grimau (Penedès, Barcelona, Spain), Journal of Archaeological Science: Reports (2026). DOI: 10.1016/j.jasrep.2025.105506 Skok, Phoebe. “Ancient shipwrecks rewrite the story of Iron Age trade.” PhysOrg. 10/14/2025. https://phys.org/news/2025-10-ancient-shipwrecks-rewrite-story-iron.html The History Blog. “600-year-old Joseon ship recovered from seabed.” 11/15/2025. https://www.thehistoryblog.com/archives/74652 The History Blog. “Ancient pleasure barge found off Alexandria coast.” 12/9/2025. https://www.thehistoryblog.com/archives/74860 The History Blog. “Charred Byzantine bread loves stamped with Christian imagery found in Turkey.” 10/13/2025. https://www.thehistoryblog.com/archives/74352 The History Blog. “Early medieval silver treasure found in Stockholm.” 10/12/2025. https://www.thehistoryblog.com/archives/74343 The History Blog. “Roman amphora with sardines found in Switzerland.” 12/15/2025. https://www.thehistoryblog.com/archives/74904 The Straits Times. “Wreck of ancient Malay vessel discovered on Pulau Melaka.” 10/31/2025. https://www.straitstimes.com/asia/se-asia/wreck-of-ancient-malay-vessel-discovered-on-pulau-melaka Thompson, Sarah. “The forgotten daughter: Eliza Monroe Hay’s story revealed in her last letters.” W&M News. 9/30/2025. https://news.wm.edu/2025/09/30/the-forgotten-daughter-eliza-monroes-story-revealed-in-her-last-letters/ Tuhkuri, Jukka. “Why Did Endurance Sink?” Polar Record 61 (2025): e23. Web. https://www.cambridge.org/core/journals/polar-record/article/why-did-endurance-sink/6CC2C2D56087035A94DEB50930B81980 Universitat de Valencia. “The victims of the Pompeii eruption wore heavy wool cloaks and tunics, suggesting different environmental conditions in summer.” 12/3/2025. https://www.uv.es/uvweb/uv-news/en/news/victims-pompeii-eruption-wore-heavy-wool-cloaks-tunics-suggesting-different-environmental-conditions-summer-1285973304159/Novetat.html?id=1286464337848&plantilla=UV_Noticies/Page/TPGDetaillNews University of Glasgow. “Archaeologists recover hundreds of Jacobite projectiles in unexplored area of Culloden.” 10/30/2025. https://www.gla.ac.uk/news/headline_1222736_en.html University of Vienna. “Neanderthal DNA reveals ancient long-distance migrations.” 10/29/2025. https://www.univie.ac.at/en/news/detail/neanderthal-dna-reveals-ancient-long-distance-migrations Zhou, H., Tao, L., Zhao, Y. et al. Exploration of hanging coffin customs and the bo people in China through comparative genomics. Nat Commun 16, 10230 (2025). https://doi.org/10.1038/s41467-025-65264-3 Zinin, Andrew. “Ancient humans mastered fire-making 400,000 years ago, study shows.” Phys.org. 10/10/2025. https://phys.org/news/2025-12-ancient-humans-mastered-years.html See omnystudio.com/listener for privacy information.

The show's coverage of things literally or figuratively unearthed in the last quarter of 2025 begins with updates, books and letters, animals, and just one exhumation. Research: Abdallah, Hanna. “Famous Easter Island statues were created without centralized management.” PLOS. Via EurekAlert. 11/26/2025. https://www.eurekalert.org/news-releases/1106805 Abdallah, Hannah. “Early humans butchered elephants using small tools and made big tools from their bones.” PLOS. Via EurekAlert. 10/8/2025. https://www.eurekalert.org/news-releases/1100481 Abdallah, Hannah. “Researchers uncover clues to mysterious origin of famous Hjortspring boat.” EurekAlert. 10/12/2025. https://www.eurekalert.org/news-releases/1108323 Archaeology Magazine. “Medieval Hoard of Silver and Pearls Discovered in Sweden.” https://archaeology.org/news/2025/10/14/medieval-hoard-of-silver-and-pearls-discovered-in-sweden/ Archaeology Magazine. “Possible Trepanation Tool Unearthed in Poland.” 11/13/2025. https://archaeology.org/news/2025/11/13/possible-trepanation-tool-unearthed-in-poland/ “Rare 5,000-year-old dog burial unearthed in Sweden.” 12/15/2025. https://news.cision.com/se/arkeologerna/r/rare-5-000-year-old-dog-burial-unearthed-in-sweden,c4282014 Arnold, Paul. “Ancient ochre crayons from Crimea reveal Neanderthals engaged in symbolic behaviors.” Phys.org. 10/30/2025. https://phys.org/news/2025-10-ancient-ochre-crayons-crimea-reveal.html Arnold, Paul. “Dating a North American rock art tradition that lasted 175 generations.” Phys.org. 11/28/2025. https://phys.org/news/2025-11-dating-north-american-art-tradition.html Bassi, Margherita. “A Single Gene Could Have Contributed to Neanderthals’ Extinction, Study Suggests.” Smithsonian. 10/30/2025. https://www.smithsonianmag.com/smart-news/a-neanderthal-gene-variant-related-to-red-blood-cells-may-have-contributed-to-their-extinction-180987586/ Benjamin Pohl, Chewing over the Norman Conquest: the Bayeux Tapestry as monastic mealtime reading, Historical Research, 2025;, htaf029, https://doi.org/10.1093/hisres/htaf029 Benzine, Vittoria. “Decoded Hieroglyphics Reveal Female Ruler of Ancient Maya City.” ArtNet. 10/27/2025. https://news.artnet.com/art-world/foundation-stone-maya-coba-woman-ruler-2704521 Berdugo, Sophie. “Easter Island statues may have 'walked' thanks to 'pendulum dynamics' and with as few as 15 people, study finds.” LiveScience. 10/19/2025. https://www.livescience.com/archaeology/easter-island-statues-may-have-walked-thanks-to-pendulum-dynamics-and-with-as-few-as-15-people-study-finds Billing, Lotte. “Fingerprint of ancient seafarer found on Scandinavia’s oldest plank boat.” EurekAlert. 10/12/2025. https://www.eurekalert.org/news-releases/1109361 Brhel, John. “Rats played major role in Easter Island’s deforestation, study reveals.” EurekAlert. 11/17/2025. https://www.eurekalert.org/news-releases/1106361 Caldwell, Elizabeth. “9 more individuals unearthed at Oaklawn could be 1921 Tulsa Race Massacre victims.” Tulsa Public Radio. 11/6/2025. https://www.publicradiotulsa.org/local-regional/2025-11-06/9-more-individuals-unearthed-at-oaklawn-could-be-1921-tulsa-race-massacre-victims Clark, Gaby. “Bayeux Tapestry could have been originally designed as mealtime reading for medieval monks.” Phys.org. 12/15/2025. https://phys.org/news/2025-12-bayeux-tapestry-mealtime-medieval-monks.html#google_vignette Cohen, Alina. “Ancient Olive Oil Processing Complex Unearthed in Tunisia.” Artnet. 11/21/2025. https://news.artnet.com/art-world/ancient-olive-oil-complex-tunisia-2717795 Cohen, Alina. “MFA Boston Restores Ownership of Historic Works by Enslaved Artist.” ArtNet. 10/30/2025. https://news.artnet.com/art-world/mfa-boston-david-drake-jars-restitution-2706594 Fergusson, Rachel. “First DNA evidence of Black Death in Edinburgh discovered on teeth of excavated teenage skeleton.” The Scotsman. 11/5/2025. https://www.scotsman.com/news/first-dna-evidence-black-death-edinburgh-discovered-teeth-excavated-teenage-skeleton-5387741 Folorunso, Caleb et al. “MOWAA Archaeology Project: Enhancing Understanding of Benin City’s Historic Urban Development and Heritage through Pre-Construction Archaeology.” Antiquity (2025): 1–10. Web. Griffith University. “Rare stone tool cache tells story of trade and ingenuity.” 12/2/2025. https://news.griffith.edu.au/2025/12/02/rare-stone-tool-cache-tells-story-of-trade-and-ingenuity/ Han, Yu et al. “The late arrival of domestic cats in China via the Silk Road after 3,500 years of human-leopard cat commensalism.” Cell Genomics, Volume 0, Issue 0, 101099. https://www.cell.com/cell-genomics/fulltext/S2666-979X(25)00355-6 Hashemi, Sara. “A Volcanic Eruption in 1345 May Have Triggered a Chain of Events That Brought the Black Death to Europe.” Smithsonian. 12/8/2025. https://www.smithsonianmag.com/smart-news/a-volcanic-eruption-in-1345-may-have-triggered-a-chain-of-events-taht-brought-the-black-death-to-europe-180987803/ Hjortkjær, Simon Thinggaard. “Mysterious signs on Teotihuacan murals may reveal an early form of Uto-Aztecan language.” PhysOrg. 10/6/2025. https://phys.org/news/2025-10-mysterious-teotihuacan-murals-reveal-early.html Institut Pasteur. “Study suggests two unsuspected pathogens struck Napoleon's army during the retreat from Russia in 1812.” Via EurekAlert. 10/24/2025. https://www.eurekalert.org/news-releases/1102613 Jones, Sam. “Shells found in Spain could be among oldest known musical instruments.” The Guardian. 12/2/2025. https://www.theguardian.com/science/2025/dec/02/neolithic-conch-like-shell-spain-catalonia-discovery-musical-instruments Kasal, Krystal. “Pahon Cave provides a look into 5,000 years of surprisingly stable Stone Age tool use.” Phys.org. 12/16/2025. https://phys.org/news/2025-12-pahon-cave-years-stable-stone.html Kristiansen, Nina. “Eight pages bound in furry seal skin may be Norway's oldest book.” Science Norway. 11/3/2025. https://www.sciencenorway.no/cultural-history-culture-history/eight-pages-bound-in-furry-seal-skin-may-be-norways-oldest-book/2571496 Kuta, Sarah. “109-Year-Old Messages in a Bottle Written by Soldiers Heading to Fight in World War I Discovered on Australian Beach.” Smithsonian. 11/6/2025. https://www.smithsonianmag.com/smart-news/109-year-old-messages-in-a-bottle-written-by-soldiers-heading-to-fight-in-world-war-i-discovered-on-australian-beach-180987649/ Kuta, Sarah. “A Storm Battered Western Alaska, Scattering Thousands of Indigenous Artifacts Across the Sand.” Smithsonian. 10/31/2025. https://www.smithsonianmag.com/smart-news/a-storm-battered-western-alaska-scattering-thousands-of-indigenous-artifacts-across-the-sand-180987606/ Kuta, Sarah. “Archaeologists Unearth More Than 100 Projectiles From an Iconic Battlefield in Scotland.” Smithsonian. 11/5/2025. https://www.smithsonianmag.com/smart-news/archaeologists-unearth-more-than-100-projectiles-from-an-iconic-battlefield-in-scotland-180987641/ Kuta, Sarah. “Hundreds of Mysterious Victorian-Era Shoes Are Washing Up on a Beach in Wales. Nobody Knows Where They Came From.” Smithsonian. 1/5/2026. https://www.smithsonianmag.com/smart-news/hundreds-of-mysterious-victorian-era-shoes-are-washing-up-on-a-beach-in-wales-nobody-knows-where-they-came-from-180987943/ Lawson-Tancred, Jo. “Golden ‘Tudor Heart’ Necklace Sheds New Light on Henry VIII’s First Marriage.” Artnet. 10/14/2025. https://news.artnet.com/art-world/tudor-heart-pendant-british-museum-fundraiser-2699544 Lawson-Tancred, Jo. “Long-Overlooked Black Veteran Identified in Rare 19th-Century Portrait.” ArtNet. 10/27/2025. https://news.artnet.com/art-world/black-veteran-thomas-phillips-portrait-identified-2704721 Lipo CP, Hunt TL, Pakarati G, Pingel T, Simmons N, Heard K, et al. (2025) Megalithic statue (moai) production on Rapa Nui (Easter Island, Chile). PLoS One 20(11): e0336251. https://doi.org/10.1371/journal.pone.0336251 Lipo, Carl P. and Terry L. Hunt. “The walking moai hypothesis: Archaeological evidence, experimental validation, and response to critics.” Journal of Archaeological Science. Volume 183, November 2025, 106383. https://www.sciencedirect.com/science/article/abs/pii/S0305440325002328 Lock, Lisa. “Pre-construction archaeology reveals Benin City's historic urban development and heritage.” 10/29/2025. https://phys.org/news/2025-10-pre-archaeology-reveals-benin-city.html#google_vignette Lock, Lisa. “Pre-construction archaeology reveals Benin City's historic urban development and heritage.” Antiquity. Via PhysOrg. 10/29/2025. https://phys.org/news/2025-10-pre-archaeology-reveals-benin-city.html#google_vignette Lynley A. Wallis et al, An exceptional assemblage of archaeological plant fibres from Windmill Way, southeast Cape York Peninsula, Australian Archaeology (2025). DOI: 10.1080/03122417.2025.2574127 Lyon, Devyn. “Oaklawn Cemetery excavation brings investigators closer to identifying Tulsa Race Massacre victims.” Fox 23. 11/6/2025. https://www.fox23.com/news/oaklawn-cemetery-excavation-brings-investigators-closer-to-identifying-tulsa-race-massacre-victims/article_67c3a6b7-2acc-44cb-93ce-3d3d0c288eca.html Marquard, Bryan. “Bob Shumway, last known survivor of the deadly Cocoanut Grove nightclub fire, dies at 101.” 11/12/2025. https://www.bostonglobe.com/2025/11/12/metro/bob-shumway-101-dies-was-last-known-cocoanut-grove-fire-survivor/?event=event12 Marta Osypińska et al, A centurion's monkey? Companion animals for the social elite in an Egyptian port on the fringes of the Roman Empire in the 1st and 2nd c. CE, Journal of Roman Archaeology (2025). 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