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Last time we spoke about the beginning of the Battle of Hong kong. Japan's rise as a threat to British interests accelerated through the 1920s and intensified after invading China. Britain's response remained contradictory—diplomatically conciliatory yet militarily apprehensive. While Singapore and Malaya received substantial reinforcements, Hong Kong was acknowledged indefensible, yet the 1936 Defence Scheme attempted to fortify it as an island fortress. Governor Northcote urgently advocated evacuation, recognizing the futility of defense. London rejected this, fearing it would demoralize China and forfeit sovereignty claims. Reinforcement requests from commanders like Grasett fell on deaf ears until Grasett independently lobbied Canadian leaders. This persistence finally convinced Churchill to dispatch two additional battalions. On December 8, 1941, Japanese forces attacked across three fronts with overwhelming force. Within hours, the RAF was destroyed on the ground, demolitions proved ineffective, and British units rapidly retreated toward the Gin Drinkers Line, facing an enemy that outnumbered and outmaneuvered them from the opening moments.   #217 The Battle of Hong Kong Part 2: the Island Aflame Welcome to the Fall and Rise of China Podcast, I am your dutiful host Craig Watson. But, before we start I want to also remind you this podcast is only made possible through the efforts of Kings and Generals over at Youtube. Perhaps you want to learn more about the history of Asia? Kings and Generals have an assortment of episodes on history of asia and much more  so go give them a look over on Youtube. So please subscribe to Kings and Generals over at Youtube and to continue helping us produce this content please check out www.patreon.com/kingsandgenerals. If you are still hungry for some more history related content, over on my channel, the Pacific War Channel where I cover the history of China and Japan from the 19th century until the end of the Pacific War. Around 1500 hours on 9 December, Colonel Doi of the 228th Regiment arrived at Needle Hill, just north of the Gin Drinkers Line, ahead of his main force. For two hours he studied the British defensive positions through binoculars, noting trenches and bunkers—and to his surprise, washing lines fluttering with white clothes. The sight spoke volumes about the 2 Royal Scots' lax discipline. Then fog descended, reducing visibility to barely twenty meters, and heavy rain obscured the landscape. Doi sensed a fleeting advantage but lost radio contact with his battalions. Worse still, the Shing Mun Redoubt lay outside his regimental boundary, making an unauthorized attack a serious breach of protocol. When his units finally arrived, supporting artillery remained unavailable, held up by demolished roads. Doi chose to attack anyway. Doi ordered the 2nd Battalion to scout the eastern approach while the 3rd Battalion spearheaded the main assault. Major Nishiyana commanded the 3rd, sending Lieutenant Wakabayashi and Kasugai with 150 volunteers to lead. The Shing Mun Redoubt itself comprised five concrete pillboxes and an artillery observation post, connected by underground tunnels named after London landmarks—Piccadilly, Haymarket, and others. The whole complex sat on small rises above Jubilee Dam, then the British Empire's tallest. Defending the redoubt was A Company, 2 Royal Scots, under Captain Jones—just three officers and 39 men. One platoon of 25 soldiers under 2nd Lieutenant Thompson held the forward positions. Against this stood 150 Japanese attackers, with another 1,500 troops in reserve. Battalion orders forbade using the concrete works as fighting positions; they were meant for the Vickers machine-gun team and artillery protection. No mines could spare the redoubt's perimeter. On the night of the 9th, roughly half the defenders sheltered in the observation post while the remainder manned pillboxes 401b and 402. At 2000 hours, Thompson led a nine-man patrol northward to check Needle Hill and Shing Mun Valley. Despite two and a half hours in the field, the patrol returned at 2220 hours without detecting the Japanese force massing just 500 meters away. By that time, Lieutenant Kasugai's assault group had crossed Jubilee Dam undetected, bypassed unmanned Post X, and assembled below Pillbox 401b. At 2200 hours, Japanese sappers cut through two lines of wire. At 2300—H-Hour—Lance Corporal Laird heard movement in the bushes and opened fire. The Japanese answered with grenades and rushed the pillbox lines. One team entered the tunnel system; another hurled grenades through the air vents. Corporal Campbell swung his Vickers toward Pillbox 401, catching Japanese headquarters personnel in the open. Sergeant Robb mustered a counter-attack force of thirteen men. Five fell as casualties—Laird, Basnett, Coyle, Casey, and Jardine. Casey was killed; only Jardine escaped. The alert triggered gunfire from the observation post's defenders, and Forward Observer Wilcox called down 4.5-inch and 6-inch artillery fire. Without strong reinforcement and leadership, four Royal Scots and an Indian sentry abandoned the northern positions and withdrew to the observation post. Captain Jones received orders from Brigade to counter-attack, but delegated the task to Thompson. As Thompson attempted to leave the observation post, he found the gate locked from outside. This calamity had a backstory: just before the attack, Thompson had admitted a civilian at the request of Force 163 (SOE's sabotage unit in Singapore). Private Wylie had taken the observation post key from Lance Naik Kishan Singh and, upon exit, locked the gate behind him. The three officers were now literally locked out of the battle. Second Lieutenant Mochizuki and his platoon infiltrated through open trenches and began attacking the observation post from above, attempting to breach the hatches. The defenders held for three hours before Japanese sappers forced explosives down the air vents. At 0230 hours, the blast killed two Indian signallers inside. Thompson sustained a severe eye wound from grenade shrapnel; Jones and Warrant Officer Mead were both wounded. The remaining fifteen defenders surrendered; eleven became casualties. Meanwhile, a Rajput patrol engaging Japanese forces in the river valley managed to drive them back toward the redoubt. One final pillbox endured for another eleven hours before suffering the same sapper treatment. By 0400 hours on 10 December, the entire redoubt was lost. For just two killed, the Japanese had achieved a decisive victory—the breakthrough that would shift the entire campaign's trajectory. By dawn, a Japanese flag flew triumphantly from Point 255.   Major-General Maltby's assessment was stark: "This was calamitous, for Shing Mun was the key to the whole of the left position." Yet the Japanese perspective differed sharply. Having achieved a breakthrough, Colonel Doi received astonishing orders to withdraw—his success had transgressed into the 230th Regiment's sector and violated the meticulously prepared war plan. Doi refused. After heated confrontation with Major-General Ito and Lieutenant-General Sakai, his insubordination was later censured, though a divisional staff officer, Oyadomani, bore the scapegoat's burden of rebuke for failing to restrain Doi's initiative. With Shing Mun secured, Doi methodically fed reinforcements into the position. Throughout December 10th, the Japanese remained uncertain of their advantage and adopted a cautious strategy, probing British lines to exploit the evident disorder. Brigadier Wallis ordered the Royal Scots to mount an immediate dawn counterattack supported by the Rajputs and artillery. Lieutenant-Colonel White demurred; his battalion lacked any reasonable prospect of success. The resulting counterattack proved half-hearted at best. At first light on December 11th, the Japanese pressed Golden Hill forcefully, only to be repulsed by Captain Newton's Rajputs and gunfire from HMS Cicala. White positioned D Company in shallow shell scrapes and rusted wire—inadequate defenses against Japanese assault. Captain Pinkerton led a desperate bayonet charge that morning, temporarily clearing the Japanese and enabling the evacuation of wounded. Yet B, C, and D Companies absorbed devastating losses; Captains Rose and Richardson fell commanding their positions. With the Royal Scots collapsing, X Company of the Winnipeg Grenadiers and armored support rushed westward to seal the widening gap along Castle Peak Road. Meanwhile, Maltby grappled with alarming reports: Japanese landings on Lantau Island southwest of Hong Kong. Heavy artillery drove them back. A second probe at Aberdeen, where Special Naval Landing Forces approached within 300 yards of the naval base, was repelled by Canadian machine-gun fire. In hindsight, these were mere feints—never intended as the primary thrust. The stratagem succeeded. Maltby retained his island reserves—the Middlesex and two Canadian battalions—precisely where they would be needed. Had Wallis executed a forceful counterattack on December 10th with the Royal Scots and brigade reserves, the Rajputs might have retaken Shing Mun while the Japanese remained disorganized. Instead, Colonel Doi faced a furious Sakai, who had flown down from 38th Division headquarters at Taipo for what amounted to a pre-court-martial examination. The moment passed. After only 48 hours of combat, Maltby concluded the mainland was indefensible. The three battalions would withdraw intact to Hong Kong Island to assume their fortress defense roles. The naval commodore objected—demolitions, supply transfers, and troop ferrying required more time. The evacuation order was deferred 24 hours until noon on December 11th. At that hour, the decision was finalized: the mainland would be abandoned under cover of darkness. Further demolitions followed—the China Light and Power Station, the cement works on Tsing Yi Island, the docks. Yet Brigadier Wallis believed this merely a precautionary measure; he anticipated holding the mainland for at least another week. The withdrawal avoided Kowloon's congested streets, where street fighting and fifth columnists might have entrapped the British—a calculation that proved prescient, as an IJA advance column of 350 men from the 3/230th infiltrated Kowloon on the morning of December 12th to cut off the retreating garrison. The Royal Scots and Canadians retired south to Shamshuipo Barracks and Jordan Road Pier in western Kowloon; the Rajputs and supporting gunners withdrew eastward to Ma Lau Tong, which anchored the fortified Devil's Peak Peninsula. Maltby intended to hold this commanding position permanently—it was easily supplied across the narrow Lyemun Strait. The evacuation proceeded largely as planned. The Canadians and Royal Scots embarked on the afternoon and evening of December 11th under Punjabi covering fire. The Punjabis faced a harder journey—a moonlit scramble along steep Kowloon hills laden with supplies but critically short of mules. One group lost its way at a crucial junction, splitting into two columns. One proceeded toward Devil's Peak as planned; Battalion Headquarters descended into Kai Tak Airport, threaded through Kowloon City, and was evacuated by Star Ferry at Tsim Sha Tsui, fighting until the final moment as the last man boarded. The Rajputs' commander, unable to reach his Punjabi counterpart, abandoned Ma Lau Tong for the closer Hai Wan line near Devil's Peak. By 0400 hours on December 12th, the Punjabis and one Rajput company, accompanied by the gunners of the 25th Medium Battery, crossed Lyemun Strait to Hong Kong Island. Morning evacuations continued with minimal Japanese interference—a surprising restraint. Naval support proved crucial. The withdrawal completed by the morning of December 13th, though 170 mules were lost to the desertion of Chinese laborers—a deprivation that would haunt the subsequent campaign. During this passage, the IJN attempted shore bombardment. The Japanese cruiser and supporting vessels found themselves outranged by the defenders' 9.2-inch guns. The damage inflicted proved sufficient to discourage future naval adventures; for the remainder of the battle, the IJN maintained a cautious distance and played only a peripheral role. The speed and execution of the withdrawal apparently caught the Japanese unprepared. Their most probable expectation had been a full-scale assault on Devil's Peak accompanied by heavy bombardment—a day earlier, an assault without artillery preparation had been driven back with severe losses. The British appeared stronger than anticipated. The defense of the mainland had lasted only five days. With the mainland secured, the Japanese pivoted toward Hong Kong Island. The first move was diplomatic rather than military. At 0900 hours on December 13th, a small boat bearing a white flag crossed the harbor. It carried Colonel Toda, Lieutenant Mizuno, Mr. Othsu Dak, and two European women—the prominent and heavily pregnant Mrs. Macdonald and Mrs. C. R. Lee, wife of the Governor's secretary, accompanied by her two dachshunds. The surrender terms were flatly rejected. Major Boxer delivered the written refusal personally. Mrs. Macdonald remained in Hong Kong to give birth; Mrs. Lee and her dogs returned to Kowloon. The Japanese commenced systematic shelling of selected targets. On December 13th, a 9.2-inch gun on Mt. Davis was silenced; Belcher's Fort sustained damage. The following day, a 3-inch mount on Mt. Davis was hit, killing Chinese gunners and triggering morale collapse; some deserted. On December 15th, the barrage shifted to the northern shoreline, deliberately targeting pillboxes. At 2100 hours that night, approximately three Japanese companies attempted crossing the harbor in rubber rafts toward Pakshawan but were driven off by machine-gun fire. Fifth columnists intensified their operations—signaling with mirrors, sniping from concealed positions, spreading propaganda to encourage Chinese desertion. Their impact might have been catastrophic had not Rear-Admiral Chan and Colonel Yee, armed with tommy guns and grenades, systematically eliminated many of these saboteurs. By December 16th, half the pillboxes between the racecourse and Lyemun Strait lay destroyed. The intended crossing site was unmistakable. On December 17th, the Japanese dispatched a second peace mission—Colonel Toda's team now accompanied by Mrs. Lee with her dachshunds and a pregnant Russian woman. Again, the overtures were rebuffed. On December 18th, the bombardment reached new intensity. Oil storage tanks ignited, sending dense black smoke cascading across the northeast corner of the island—perfect concealment for what was to come. All signs pointed to imminent assault.  I want to note something here, you sometimes hear about how race played a role in the Pacific War and indeed it did. Racist attitudes were found on both the western and Japanese side of the war. There is a fantastic book dedicated to this by the way called, War without Mercy by John Dower, highly recommend it. What is interesting is how these racial attitudes actually affected decision making during the war. Take General Sakai's night amphibious assault for example. Western soldiers such as the Canadians in Hong Kong reported they were told by their commanders that quote "Don't worry about the Japanese, they can't see at night, they all wear glasses" another Canadian soldier wrote in a diary "They don't see well, especially at night we knew this as a matter of fact." Indeed the week before the outbreak of the battle of Hong Kong, Canadian officers attending a briefing by a British officer were informed that "Japan's aircraft were mostly obsolete, its air force had little practice in night flying, and its pilots were myopic and thus unable to carry out dive-bombing attacks". You might be asking yourself, why did they think the Japanese were myopic? The scientific explanation of the day was this "That the Japanese suffered widespread inner-ear damage. What caused this? Japanese motherhood, the practice of strapping babies to their mothers backs, it was explained caused their heads to bounce about, like when they harvested rice and permanently impaired their sense of balance". I particularly love this quote, one of my professors dedicated an entire class to the bizarre racial attitudes before and after the pacific war. There was a belief the Japanese could not see well at night, many western air force commanders actually believed there were times of day like at dawn or dusk where Japanese pilots would not operate because of this hindrance. American military commentator Fletcher Pratt in 1939 analyzed Japan's military strengths and explained it had four major weaknesses. The first was scarcity of resources such as iron, and steel. The second was that the Japanese "can neither make good airplanes nor fly them well" as a result of " the Japanese as a race have defects of the tubes of the inner ear, just as they are generally myopic. This gives them a defective sense of balance, the one physical sense in which an aviator is not permitted to be deficient.". The third was that the Japanese were short-tempered and were inclined to waste men unnecessarily when operations did not go well. The fourth was that the Japanese would simply never date to provoke a war with the US. Again Mr Pratt was an American military commentator whose information came from multiple accounts given by high ranking military officials! The British military maintained that the Japanese avoided night operations on land because they were simply incapable of caring them out well, while they avoided nighttime aerial attacks, as well as dive-bombing for the same reasons Pratt said quote "their pilots were poor and their aircraft inferior.". So take this all to mind when I talk about how certain ranking officers go about making their decisions. By the evening of 14 December, evacuated mainland units had regrouped on Hong Kong Island. The defensive structure was restructured into two brigades: Brigadier Wallis commanded the East Brigade from Taitam Gap, while Brigadier Lawson headed the West Brigade from Wongneichong Gap. This reorganization placed the 5/7 Rajputs across the north-east perimeter, defending over 3,500 metres of coastline with B Company positioned on the hills behind Taikoo Docks. The Royal Rifles of Canada held the north-east corner from Stanley to points south, with reserve positions at Lyemun. Two HKVDC companies supported from Taitam Valley and Pottinger Gap, while the veteran Hughsiliers manned the North Point power station. British and Canadian artillery provided fire support across the northern approaches. The West Brigade held the north-western and south-western shores. The 2/14 Punjab stretched from Causeway Bay to Belcher's Point, protecting Government House and General Maltby's headquarters, with battalion headquarters at Mid-Level. The Winnipeg Grenadiers covered the south-west from Wanchai Gap, with one company detached to the brigade headquarters at Wongneichong Gap. The 2 Royal Scots, severely mauled at Shing Mun, were held in reserve with fresh replacements from the HKVDC. The Middlesex Regiment's companies were dispersed along 72 pillboxes encircling the entire shoreline, while an improvised Z Company of clerks, musicians and cooks defended battalion headquarters at Leighton Hill. Supporting artillery included 9.2-inch and 6-inch guns on Mt Davis and 4.7-inch guns at Belcher's Point. As darkness fell on 17 December, Japanese reconnaissance swimmers reached Taikoo, confirming the crossing site despite detection. Reinforcements arrived: 18 additional heavy bombers from Guangzhou and 26 fighters from Taiwan joined the aerial assault. The crescendo of artillery fire on the 18th, combined with masses of small craft gathering across the harbour, signalled the imminent invasion. Japanese divisional headquarters shifted to Ma Tau Wei near Kai Tak Airport; the 23rd Army moved to Taipo. The invasion force disposed itself with the right flank embarking from east and west of Kai Tak, the left from Devil's Hill area. At 1800 hours, the invasion order was issued; by 1930 hours Sakai himself arrived in Kowloon to oversee the crossing. At precisely 2000 hours, the 2/228th Regiment silently paddled their collapsible craft toward Taikoo Docks and the nearby sugar factory as artillery support commenced. Colonel Doi embarked with 80 headquarters personnel aboard a large barge, leading the second wave. The conditions favoured the invaders—a moonless night, sporadic showers, and thick black smoke from burning oil tanks obscured their movement. They reached the midpoint undetected before searchlights and machine-gun fire scattered the small boats, separating commanders from their units. Despite this chaos, the assault pressed forward. At 2140 hours the artillery shifted to deeper targets; at 2145 hours the first wave of 3/230th landed at North Point, followed minutes later by 2/228th and then 2/229th. Three red flares signalled a successful landing. All six Japanese battalions were ashore by midnight, though wire fencing delayed their advance and Bren carriers added to the confusion on the beach. General Sano arrived at Taikoo one hour later. The 5/7 Rajputs bore the initial brunt of the assault. Despite days of preliminary shelling, the Rajputs mounted a stubborn defence; Japanese casualties mounted rapidly. The anti-tank company suffered so grievously that only a single gun remained operational. The Japanese plan was tactical rather than frontal—bypass isolated positions for later elimination and push rapidly toward high ground. Overwhelmed by numerical superiority and losing most of their officers, Rajput resistance gradually crumbled. Contradicting all evidence, Maltby remained convinced the main Japanese assault would strike directly at Victoria from Kowloon. He therefore withheld the counter-attack, instead dispatching a platoon of Middlesex troops, Royal Marines, naval personnel, and the Rajputs' reserve company—supported by artillery—to establish a defensive line blocking the Japanese advance toward Central District. Three HKVDC armoured cars were sent to protect East Brigade headquarters; two more reinforced the Middlesex battalion headquarters. It was manifestly inadequate against six Japanese battalions. In post-war dispatches, Maltby conceded his grave miscalculation: he believed he faced at most two battalions, not a full division. As the 3/230th broke through D Company of the 5/7 Rajputs, the 2/230th came ashore nearby and wheeled westward toward Victoria. Their advance halted abruptly at the North Point power station, held by an extraordinary force: four officers and 36 men of the HKVDC Hughsiliers Platoon—alongside 39 civilian volunteers from China Light & Power and Hong Kong Electric, including the station manager Vincent Sorby—plus eight Free French soldiers commanded by Captain Jacques Egal, a Shanghai businessman turned soldier. Without exception, these men were World War I veterans, many aged 55 or older. Some had fought in the Boer War. Major J. J. Patterson, the Hughsiliers' commander, had served with Allenby's Camel Corps and been mentioned in dispatches six times; he was chairman of Jardine Matheson and a legislative councillor. Private Sir Edward Des Voeux, 8th Baronet, a millionaire bullion trader and secretary of the Hong Kong Club, had enlisted as a private when deemed too old for mobilization. Private T. A. Pearce, 67 years old, was chairman of J. D. Hutchison & Company and secretary of the Hong Kong Jockey Club. Captain Bruch, the second-in-command, aged 60, chaired a major trading house. The list extended through Hong Kong's business elite, each choosing to fight rather than flee. These old men held an entire regiment at bay. When Patterson called for aid, Maltby dispatched an HKVDC armoured car with a platoon from Z Company, 1 Middlesex, but the reinforcement was ambushed before reaching the station; only nine soldiers, including 2nd Lieutenant Caruthers, broke through. Unable to dislodge the defenders by assault, the Japanese resorted to bombardment. By 0145 hours on 19 December, surrounded and ammunition exhausted, the defenders withdrew to King's Road behind a disabled bus. The Japanese deployed three machine guns, killing or mortally wounding all but Private Geoghan. A Japanese officer, believing all dead, cautiously approached—only to have Geoghan, despite his wounds, surge from cover and charge. He killed the officer and four soldiers before collapsing from wounds. Somehow Geoghan survived. Those old men—civilians and reservists, businessmen and veterans—held the entire western Japanese advance for 18 hours, buying Maltby precious time to withdraw forces and establish a new defensive line. Their stand at North Point became one of the campaign's most improbable acts of defiance. As the 2/229th Regiment advanced southward toward Mt Parker, the 3/229th landed at Aldrich Bay and turned eastward toward Lyemun, where they seized an HKVDC 6-inch gun. Major Bishop of the Royal Rifles of Canada, unaware of the landings, dispatched 15 Platoon under Lieutenant Scott to check on A Company of the Rajputs. Unexpectedly, they encountered armed men in civilian clothes at Lyemun's gate—the first indication of the Japanese presence on the island. Yet senior officers dismissed initial reports of landings and lost positions as exaggerated, a critical miscalculation that proved catastrophic. At Lyemun Fort, the 5th Anti-aircraft Battery of the HKVDC was caught completely unaware and surrendered after minimal resistance. The Japanese then committed one of many atrocities that would characterize the battle, bayoneting 29 survivors. Alerted by 15 Platoon's report, Bishop attempted a counter-attack with two platoons to retake the fort, but the defenders could not scale the six-meter wall and withdrew with nine men killed. As the 2/229th pressed southward toward Mt Parker, they overran the Salesian Mission, which had been converted into an Advance Dressing Station. No. 8 Company of the 2/229th systematized a massacre of medical personnel and the wounded—an atrocity that would later become pivotal evidence at Colonel Tanaka's war crimes trial. Yet amid the chaos, several medical staff and wounded survived to testify: Gunners Y. K. Chan and Martin H. C. Tso of the 5th Battery, Captain Osler Thomas of the HKVDC, Captain Martin Banfill of the Royal Canadian Medical Corps, and Corporal Norman Leath of the Royal Army Medical Corps. C Company of the Royal Rifles, reinforced with captured Japanese machine guns abandoned by fleeing Rajputs, inflicted heavy casualties on the attackers, with one Japanese company suffering over 65 percent losses. Yet overwhelmed by superior numbers and suffering nearly two platoons worth of casualties themselves, the Canadians were forced to withdraw, leaving only a reinforcement platoon under Lieutenant Blaver on Mt Parker. When Captain Clerke arrived at dawn with 16 Platoon to reinforce the position, he found over 100 Japanese already entrenched. With no artillery support and only two platoons available, Clerke had no choice but to withdraw, abandoning Mt Parker to the enemy. By dawn on the 19th, the East Brigade faced catastrophe. Infantry strength had been halved, and losses of artillery were equally devastating. A series of misunderstandings and misinterpreted orders led coastal gun crews at Capes D'Aguilar and Collinson to destroy their own guns in confusion or lose them to the advancing Japanese. Of the entire artillery complement, only one 18-pounder and two 3.7-inch field guns remained operational. Wongneichong—literally "yellow muddy creek" in Chinese—occupies the center of Hong Kong Island, a valley separating the eastern hills (Mt Parker, Mt Butler, Jardine's Lookout) from the western massif (Mt Nicholson, Mt Cameron, Victoria Peak). This narrow gap formed the critical artery linking northern and southern Hong Kong, making Brigadier Lawson's decision to place West Brigade Headquarters there strategically sound yet tactically vulnerable. Recognizing the exposed position after the landings, Major Lyndon had located an alternative site south of Mt Nicholson, scheduled to open the following day. In response to the Japanese landings, Lawson dispatched three platoons of Winnipeg Grenadiers to block the advance. Lieutenant C. D. French took 18 Platoon to Mt Butler, Lieutenant G. A. Birkett's 17 Platoon moved to Jardine's Lookout, and Lieutenant L. B. Corrigan's platoon took the north-west approach to the Gap. As on Mt Parker, both French and Birkett were killed almost immediately, their small forces overwhelmed by battalion-strength enemy forces with artillery support. By morning on the 19th, two battalions each of the 230th and 228th Regiments were pushing for the high ground. The 2/230th rapidly occupied Jardine's Lookout while the 3/230th moved to Mt Nicholson and the 2/228th advanced toward the Gap itself. No. 3 Company of the HKVDC under Major E. Stewart held pillboxes around Jardine's Lookout, while No. 1 Company under Captain Penn defended Taitam Valley with forward positions at Quarry Gap. The pillboxes, despite heavy bombardment, held longer than anticipated—some for as long as 24 hours. Stewart maintained his company headquarters until the 22nd, four days of continuous fighting without adequate ammunition, food, or water. No. 3 Company suffered 80 percent casualties and ceased to exist as a cohesive unit. Realizing that the enemy had penetrated to Mt Butler, Brigadier Lawson decided counter-attack was essential. Major A. B. Gresham of A Company, Winnipeg Grenadiers, was ordered to retake Mt Butler and clear Jardine's Lookout. The Canadians initially succeeded, with Warrant Officer 2 J. R. Osborne leading a bayonet charge, but a strong counter-attack by three Japanese companies drove them back by 2200 hours. The Canadians held firm until 1500 hours, when Gresham attempted surrender despite waving a white flag—the Japanese shot him regardless. In the chaos that followed, a Canadian killed a Japanese officer in response, triggering a grenade barrage. Warrant Officer Osborne caught the grenades and hurled them back as fast as they came, but one landed in an impossible position. Without hesitation, Osborne threw himself on the grenade to save his comrades. This act of supreme self-sacrifice earned him a Victoria Cross—the first Canadian VC of World War II. At dawn on the 19th, Maltby dispatched A Company of the 2 Royal Scots under Captain K. J. Campbell to reinforce the Gap, but they lost all their officers with only 15 men reaching Lawson's headquarters. A group of sailors under Commander A. L. Pears came from the south, but were ambushed en route; only a few reached the Postbridge—a house just south of the Gap—which became an isolated strongpoint. The 3/230th captured the police station perched on a mound at the southern point of the Gap, then swept eastward to seize the anti-aircraft guns of 7th Battery (barely 250 meters from brigade headquarters) and continued uphill toward Taitam Hill to capture additional 6-inch and 3.7-inch guns. Maltby's response was to call down final protective fire from the HKSRA in Happy Valley, inflicting massive casualties on the 3/230th. At 1000 hours on the 19th, Lawson reported that his headquarters was surrounded and he was about to "go outside and shoot it out." Captain H. A. Bush provided covering fire as Lawson and his entire staff, including Middlesex signallers, were cut down by machine-gun fire across the Gap. Lawson's body was discovered two days later halfway up the hill behind his headquarters, dead from a gunshot wound to the thigh. Lieutenant Kerfoot of the 2/14 Punjab with his three Bren carriers arrived minutes too late to save him. IJA who saw the fight made a note stating "he died heroically". At 1330 hours on the 19th, Maltby issued "Operation Order No. 6" calling for a massive counter-attack to commence 90 minutes later. The plan was ambitious: A and D Companies of the 2/14 Punjab were to attack east from Victoria to North Point to relieve the Hughsiliers, while HQ Company of the Winnipeg Grenadiers and the 2 Royal Scots were to attack the Gap and Jardine's Lookout. Eight field guns were promised but never materialized. There was no reconnaissance, no proper orders, and minimal coordination. The Canadians were to rendezvous with the 2 Royal Scots at Middle Gap at 1530 hours, but the Scots were late; the Canadians advanced without them. Captain Pinkerton of D Company, 2 Royal Scots, was ordered at the last minute to attack up Wongneichong Gap Road—the same route A Company had taken only seven hours earlier and been decimated—because it was reported as "lightly held." Captain A. M. S. Slater-Brown led the advance with three Bren carriers and attached engineers, followed by D Company of the Winnipeg Grenadiers. Just as the carriers reached the burnt-out trucks of A Company, they too were ambushed. Mortars and machine-gun fire rained down from Jardine's Lookout, where the Japanese occupied captured HKVDC pillboxes. Slater-Brown and 2nd Lieutenant Bell, the battalion intelligence officer, were killed instantly. The Royal Scots waited in the roadside ditches until 0200 hours before launching an attack on the police station, reaching the steps before Pinkerton was severely wounded. Captain Ford's composite company attack at 0300 hours also failed. Simultaneously, C Company under Lieutenant F. L. Stanier attacked Jardine's Lookout—also unsuccessfully. This series of piecemeal assaults cost the Royal Scots eight officers and 68 soldiers. Growing increasingly desperate, Maltby ordered Major Hodkinson, Officer Commanding HQ Company of the Winnipeg Grenadiers, to attack the Gap and proceed to Mt Parker. Requesting reinforcements from A Company and the Royal Scots, Hodkinson launched his assault with covering fire from Lieutenant Corrigan on Mt Nicholson. The Grenadiers managed to reach Mt Nicholson with only five unwounded men, though Corrigan's group advanced to within 300 meters of the Gap road. Then came an unexpected stroke of fortune: while skirting Mt Nicholson, Hodkinson's group stumbled upon approximately 500 Japanese—probably from the 3/230th—eating lunch without posting sentries. The Winnipeg Grenadiers unleashed devastating fire, inflicting heavy casualties. By 1745 hours, Hodkinson's force was only 100 meters from Repulse Bay Road. With four men and a 2-inch mortar, Hodkinson worked his way to the abandoned brigade headquarters, bringing 20 walking wounded with him. He established a foothold at the Gap, receiving orders to attack the police station at 2200 hours. Two HKVDC armoured cars with Vickers machine guns came in support, but accurate enemy fire disabled both. Like Pinkerton before him, Hodkinson reached near his objective before being severely wounded. For this action of determination and courage, Hodkinson was awarded the Distinguished Service Order. By the morning of the 20th, the Japanese had consolidated control of the Gap, but elements of D Company, Winnipeg Grenadiers, still held various pillboxes north of the position. Initially, 17 and 18 Platoons occupied forward positions with Company Headquarters and 16 Platoon in reserve, positioned across Wongneichong Road almost directly opposite brigade headquarters. Forward positions were rapidly overrun and cut off from the company. They fought without officers until withdrawal to battalion headquarters became necessary. With Captain A. S. Bowman killed and Captain R. W. Philips wounded, command fell to Lieutenant T. A. Blackwood. An attempt by B Company to relieve D Company on the evening of the 20th failed catastrophically, killing all officers and 29 men. With fewer than 50 men remaining—all wounded—Lieutenant Blackwood continued inflicting heavy casualties on the Japanese until 22 December, when exhaustion and the complete absence of ammunition, food, and water forced surrender. D Company killed over 200 Japanese soldiers. Post-war Japanese reports refused to believe that a single company had held the Gap for so long. For their stubborn defense, Philips and Blackwood were awarded the Military Cross, and three enlisted men received the Military Medal. The battle of Wongneichong Gap was characterized by fragmented planning and poor coordination. On the night of the 19th-20th, no fewer than three separate companies attacked the police station, with another company assaulting Jardine's Lookout—all within five hours, all independently organized by local commanders. Had these disparate actions been coordinated into a single simultaneous assault, fortress headquarters' objectives might well have been achieved. By the end of the 20th, the British had lost the vital ground of Wongneichong, though Postbridge House remained as an isolated holdout. For the Japanese, Wongneichong became the single costliest engagement since the invasion began, with over 800 casualties and the regimental commander of the 3/230th seriously wounded. I would like to take this time to remind you all that this podcast is only made possible through the efforts of Kings and Generals over at Youtube. Please go subscribe to Kings and Generals over at Youtube and to continue helping us produce this content please check out www.patreon.com/kingsandgenerals. If you are still hungry after that, give my personal channel a look over at The Pacific War Channel at Youtube, it would mean a lot to me.   Japanese landings on 18-19 December overwhelmed the East Brigade. Brigadier Lawson died defending the vital Gap. Desperate, uncoordinated counter-attacks by British and Canadian troops failed to dislodge the enemy. D Company Winnipeg Grenadiers held the position for four days against overwhelming odds before surrendering. The Japanese suffered 800 casualties but secured this critical strategic ground.

Credits: 0.75 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-500 Overview: To celebrate our 500th episode, each member of our team revisits a popular topic from the podcast's earlier installments—GLP-1s, cervical and breast cancer screening, diet and exercise, contraception, hypertension, and lipid management—to trace how the evidence and guidelines have changed since it was first covered. Whether you're catching up or reinforcing what you know, this milestone episode helps you bring the latest evidence into everyday patient care. Guest: Robert Baldor, MD, Alan Ehrlich, MD, Susan Feeney, DNP, FNP-BC; FAANP, Jillian Joseph, PA, Mariyan L. Montaque, DNP, FNP-BC, Jill Terrien PhD, ANP-BC, FAAN   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  Episode resource links:  Zhou H et al.  Evaluation and Comparison of the PREVENT and Pooled Cohort Equations for 10‐Year Atherosclerotic Cardiovascular Risk Prediction. Journal of the American Heart Association Volume 14, Number 4 Goff DC et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association task force on practice guidelines. Circulation. 2014;129:S49–S73. Circulation. 2018 Jul 24;138(4):345-355.  eClinicalMedicine 2025: 103741. Curry, J. (2018). Screening for cervical cancer: US Preventive Services Task Force Recommendation Statement. JAMA.320(7):674-686. doi:10.1001/jama.2018.10897 https://www.ncbi.nlm.nih.gov/pubmed/30140884  Perkins RB, Wolf AMD, Church TR, et al. Self-collected vaginal specimens for human papillomavirus testing and guidance on screening exit: An update to the American Cancer Society cervical cancer screening guideline. CA Cancer J Clin. 2026;e70041. doi:10.3322/caac.70041   Screening for Cervical Cancer (2026). Obstetrics & Gynecology, 148(1), e63-e67. https://doi.org/10.1097/AOG.0000000000006257  Jad Zeitouni, Nosayaba Osazuwa-Peters, Yusuf Dundar, Gregory Zimet, Mark A. Varvares. (2025). Two decades of the HPV vaccine: its promise, progress, prospects, projections, and posterity, The Lancet Regional Health - Americas, (51), https://doi.org/10.1016/j.lana.2025.101243 Diabetes, Obesity and Metabolism 28, no. 6 (2026): 5043–5057, https://doi.org/10.1111/dom.70698.  Relationship of early rapid weight loss to efficacy and safety of tirzepatide and semaglutide for obesity: SURMOUNT-5 post hoc analysis. Am J Med. 2026 Jul;139(7):913-921. doi: 10.1016/j.amjmed.2026.03.010 US Preventive Services Task Force; Nicholson WK, Silverstein M, Wong JB, et al. Screening for breast cancer: US Preventive Services Task Force recommendation statement. JAMA. 2024;331(22):1918–1930.  Trentham-Dietz A, Chapman CH, Jayasekera J, et al. Collaborative modeling to compare different breast cancer screening strategies: a decision analysis for the US Preventive Services Task Force. JAMA. 2024;331(22):1931–1946. Giaquinto AN, Sung H, Miller KD, et al. Breast cancer statistics, 2022. CA Cancer J Clin. 2022;72(6):524–541.  Qaseem A, Harrod CS, Balk EM, et al. Screening for breast cancer in asymptomatic, average-risk adult females: a guidance statement from the American College of Physicians (Version 2). Ann Intern Med. 2026.:  American Cancer Society. Breast Cancer Facts & Figures 2022–2024. Atlanta, GA: American Cancer Society, 2022.  Hu X, Chehal PK, Kaplan C, et al. Racial differences in patient-reported symptoms and adherence to adjuvant endocrine therapy among women with early-stage, hormone receptor-positive breast cancer. JAMA Netw Open. 2022;5(8):e2225485.  Torres JM, Sodipo MO, Hopkins MF, Chandler PD, Warner ET. Racial differences in breast cancer survival between Black and White women according to tumor subtype: a systematic review and meta-analysis. J Clin Oncol. 2024;42(35):4225–4234.  Bailey ZD, Krieger N, Agénor M, Graves J, Linos N, Bassett MT. Structural racism and health inequities in the USA: evidence and interventions. Lancet. 2017;389(10077):1453–1463. Hypertension. 2026;83:00–00. DOI: 10.1161/HYPERTENSIONAHA.125.25787 Allen RH, Bartz D. Opill: The Over-the-Counter Contraceptive Pill. Obstet Gynecol. 2024;143(2):184-188. doi:10.1097/AOG.0000000000005455  Cahill EP, Kaur S. Advances in contraception research and development. Curr Opin Obstet Gynecol. 2020;32(6):393-398. doi:10.1097/GCO.0000000000000666  Charles DN, Nagarsheth M, Oshman L. Pain Management for IUD Insertion in Primary Care. Am Fam Physician. 2025;111(4):299-301.  Chen, C., Strasser, J., Banawa, R., Luo, Q., Bodas, M., Castruccio-Prince, C., Das, K., & Pittman, P. (2022). Who is providing contraception care in the United States? An observational study of the contraception workforce. American journal of obstetrics and gynecology, 226(2), 232.e1–232.e11. https://doi.org/10.1016/j.ajog.2021.08.015  Diedrich,J., Klein, D. Peipert, J.(2017). Long-acting reversible contraception in adolescents: a systematic review and meta-analysis, Am J Ob Gyn, April 2017. http://dx.doi.org/10.1016/j.ajog.2016.12.024  Li RHW, Lo SST, Gemzell-Danielsson K, Fong CHY, Ho PC, Ng EHY. Oral emergency contraception with levonorgestrel plus piroxicam: a randomised double-blind placebo-controlled trial. Lancet. 2023;402(10405):851-858. doi:10.1016/S0140-6736(23)01240-0  Mørch LS, Meaidi A, Corn G, Hargreave M, Wessel Skovlund C. Breast Cancer in Users of Levonorgestrel-Releasing Intrauterine Systems. JAMA. 2024;332(18):1578–1580. doi:10.1001/jama.2024.18575  Nguyen AT, Curtis KM, Tepper NK, et al. U.S. Medical Eligibility Criteria for Contraceptive Use, 2024. MMWR Recomm Rep. 2024;73(4):1-126. Published 2024 Aug 8. doi:10.15585/mmwr.rr7304a1  Paradise SL, Landis CA, Klein DA. Evidence Based Contraception: Common Questions and Answers. American Family Physician. 2022. https://www.aafp.org/afp/2022/0900/contraception The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

This week we review the use of right axillary artery access for aortic valvuloplasty in infants. Why would this approach potentially offer advantages versus the more traditional femoral or even carotid approach? What are the particular dangers of this approach? How should the interventionist pick the approach when planning an aortic valvuloplasty in an infant with valvar aortic stenosis? We speak with Dr. Jameel Al-Ata of King Faisal Specialist Hospital in Jeddah, Saudi Arabia this week. DOI: 10.1007/s00246-025-03991-6

How do you create fitness classes that members actively choose, talk about, and have a hard time replacing? For boutique fitness studio owners, stronger member retention and loyalty often start with something most studios leave largely to chance: how people actually experience and remember a class. In this episode, Fitcarma Experience Designer Shay Kostabi introduces The Two Moment Rule, our framework for intentionally shaping the two moments that can carry disproportionate weight in how members remember an experience: the emotional peak and the ending. We explore the psychology behind the peak-end rule and how it applies specifically to boutique fitness, group fitness class design, instructor training, music, coaching, emotional arc, and class structure. You'll learn why the hardest part of a workout isn't automatically the most memorable, how Convergence happens when movement, music, coaching, energy, and emotion work together toward the same emotional outcome, why constant intensity can actually cause members to disengage through what we call The Mad Max Effect, and why a class that simply stops is very different from an experience that ends with true Resolution. If the best parts of your class experience exist only inside the instincts of your strongest instructors, your brand doesn't own that experience yet. At Fitcarma, our Experience Design work draws from established research in psychology, behavioral science, flow, belonging, memory, and human performance, then translates those principles specifically into boutique fitness. We help studio owners turn those insights into a proprietary class experience that can be built into class architecture, coaching methodology, instructor training, observation standards, and a Playbook your entire team can use. Your members are going to remember these moments whether you plan for them or not. You might as well make them count. Want to build a more distinctive, memorable, and difficult-to-replace class experience for your studio? Book a Fit Call with us: https://fitcarma.com/northstar Research referenced Fredrickson, B. L., & Kahneman, D. (1993). "Duration Neglect in Retrospective Evaluations of Affective Episodes." Journal of Personality and Social Psychology, 65(1), 45–55. DOI: 10.1037/0022-3514.65.1.45 Alaybek, B., Dalal, R. S., Fyffe, S., Aitken, J. A., Zhou, Y., Qu, X., Roman, A., & Baines, J. I. (2022). "All's Well That Ends (and Peaks) Well? A Meta-Analysis of the Peak-End Rule and Duration Neglect." Organizational Behavior and Human Decision Processes, 170, 104149. DOI: 10.1016/j.obhdp.2022.104149 Film referenced Mad Max: Fury Road (2015), directed by George Miller. Warner Bros. Pictures, Village Roadshow Pictures, Kennedy Miller Mitchell.

The most powerful thing your patient can do for their health isn't hitting 10,000 steps. It's taking the first 2,000 more. In this episode, Dustin Jones breaks down two major studies on physical activity and step counts — and what they mean for the people who feel most defeated by the guidelines. If you work with adults who are currently sedentary, this is the reframe that changes how you set goals. What you'll take away: Why the standard guidelines (150 min/week, 10,000 steps) backfire with sedentary patients The step-count data: 2,000 → 4,000 steps = 36% lower risk of all-cause mortality; 7,000 steps = 47%, plus 38% less dementia, 28% fewer falls, 22% fewer depressive symptoms Why a patient's past inactivity doesn't disqualify them — inactive → active = 22% lower mortality, regardless of history. The "no-plateau rule": benefit slopes flatten but never flatline, so you never stop progressing How to treat activity like progressive loading and celebrate the first jump without selling it short. Chapters: 00:00 — Why the guidelines feel impossible for sedentary patients 02:21 — Fitness is a spectrum, not a destination 02:40 — The step-count data: 4,000 vs. 7,000 steps 07:10 — What this means for your sedentary patients 09:22 — Starting beats never: your patient's past isn't a sentence 11:43 — The no-plateau rule: don't stop at 4,000 Want stats like these in your inbox every week? Join the free MMOA Digest

In this episode of Communicable, Amy Legg (Brisbane, Australia), Rekha Pai Mangalore (Melbourne, Australia) & Angela Huttner (Geneva, Switzerland) return for the third part of the ‘We will make you love PK/PD' series. The hosts are joined by two experts, Amanda Gwee (Melbourne, Australia) & Sebastian Wicha (Hamburg, Germany), to dive into an important application of PK/PD: model-informed precision dosing (MIPD), and how it allows for more informed, individualised dosing decisions. The episode also covers the open-access educational tools, KidsCalc and TDMx, developed by Gwee and Wicha respectively, and the steps clinicians can take to put MIPD into practice, keeping the individual patient at the centre of dosing decisions.Resources TDMx, https://www.tdmx.eu/KidsCalc, https://www.kidscalc.org/Further readingBroeker A, et al. Towards precision dosing of vancomycin: a systematic evaluation of pharmacometric models for Bayesian forecasting. CMI 2019. DOI: 10.1016/j.cmi.2019.02.029Brusamarello C, et al. How important are MIC determination methods when targeting vancomycin levels in patients with Staphylococcus aureus infections? J Antimicrob Chemother 2021. DOI: 10.1093/jac/dkab065De Cock PA, et al. Bedside model-informed precision dosing of vancomycin in severely ill neonates and children in Belgium (the BENEFICIAL trial): a multicentre, randomised controlled trial. Lancet Child Adolesc Health 2026. DOI: 10.1016/S2352-4642(25)00385-2  Gwee A, et al. Identifying a therapeutic target for vancomycin against staphylococci in young infants. J Antimicrob Chemother 2022. DOI: 10.1093/jac/dkab469Haiping X, et al. Model-informed precision dosing of vancomycin in children 3 months to 18 years of age using Australia-wide data. Antimicrob Agents Chemother 2026. DOI: 10.1128/aac.01840-25  Harwood K, et al. Refining Absolute GFR Estimation in Children: Development and Validation of the GROW-GFR Equation. Front Pharmacol 2026. Minichmayr IK, et al. Model-informed precision dosing: State of the art and future perspectives. Adv Drug Deliv Rev 2024. DOI: 10.1016/j.addr.2024.115421Starp J, et al. Towards model-informed precision dosing of intravenous linezolid: a multicentre external evaluation of pharmacokinetic models in critically ill adults. CMI 2026. DOI: 10.1016/j.cmi.2025.08.032Wilkins AL, et al. Individualized vancomycin dosing in infants: prospective evaluation of an online dose calculator. Int J Antimicrob Agents 2023. DOI: 10.1016/j.ijantimicag.2023.106728 US National Kidney Foundation for different equations for kidney function estimates as related to drug dosing – estimating kidney function for medication related decisions: Frequently Asked Questions | National Kidney Foundation

Inflammation is an important and necessary part of the body's healing process. It's also long been a wellness buzzword used to sell products that do very little to treat it. This week, we look at inflammation through the lens of a new Mother Jones article, “The Great Inflammation Panic,” including an interview with the author, Julia Métraux, in segment two. We'll also discuss what inflammation is, how wellness influencers weaponize it, and what it represents in the context of Ayurveda. Show Notes The Great Inflammation Panic Chronic Inflammation and Cancer NIH Autoimmune Diseases Celiac Disease Cambridge press release — "Chronic diseases misdiagnosed as psychosomatic can lead to long term damage" Sloan et al., "I still can't forget those words" — Rheumatology (2025), DOI 10.1093/rheumatology/keaf115 Vasculitis diagnostic-delay data — PubMed Miranda Fricker interview — Philosophy Bites Bleuler 1911 coinage — NCBI Bookshelf, The Metamorphosis of Autism Bleuler's original 1911 text excerpt — Autism History Project Sontag, "Illness as Metaphor" — full text, NYRB Louise Hay — Natural Ways to Treat Autoimmune Disease Gabor Maté, When the Body Says No — critical review, Globe and Mail Learn more about your ad choices. Visit megaphone.fm/adchoices

We're pretty good at deciding what we want. The harder part is working out why we want it, whether the goal actually belongs to us, and what we need to do today to move towards it.In this episode, I break down my approach to values, goals, strategy and action, exploring the psychology of self-concordance, behavioural activation and motivation, and how I use this framework to create a realistic morning routine when life is already full.I also introduce Weekly Friction, where this week I'm questioning when social media stops being work and starts becoming scrolling.Research: Sheldon, K. M., & Elliot, A. J. (1999). Goal striving, need satisfaction, and longitudinal well-being: The Self-Concordance Model. Journal of Personality and Social Psychology, 76(3), 482–497.DOI: 10.1037/0022-3514.76.3.482Sezer, B., et al. (2025). Goal motives, goal-regulatory processes, psychological needs, and well-being: A systematic review and meta-analysis. Motivation Science, 11(3), 259–276.DOI: 10.1037/mot0000366

Today's crossword, a debut (

A #Research paper recently #Published in Volume 18 of Aging, titled “Slowing intervertebral disc aging in mice through long-term systemic treatment with the senolytic BCL-2/BCL-xL proteolysis targeting chimera (PROTAC) 753b,” examines whether the senolytic PROTAC 753b can slow age-related intervertebral disc degeneration (IDD) in mice. Long-term systemic treatment with 753b reduced key features of disc degeneration in 22-month-old male mice, including matrix breakdown, loss of disc aggrecan, age-related structural changes, and inflammatory markers such as IL-6 and TNFα. These benefits, however, were not observed in female mice, highlighting potential sex-based differences in the role of cellular senescence in IDD and the response to senolytic therapies. DOI - https://doi.org/10.18632/aging.206394 Corresponding author - Nam Viet Vo - nvv1@pitt.edu Abstract video - https://www.youtube.com/watch?v=t0z4MULDr1A Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206394 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, intervertebral disc aging, cellular senescence, senolytic, anti-apoptosis, PROTAC-753b To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Join Dr. Clancy  and his guests, Drs. Ganesan and Mangala, as they discuss what is known about the microbiome, its relation to disease and how we can promote a healthy microbiome. Episode Transcript CE Credit Available Host: Gerard Clancy, MD Senior Associate Dean for External Affairs Professor of Psychiatry and Emergency Medicine University of Iowa Carver College of Medicine Guests: Sukirth Ganesan, DDS, PhD, MPH Centennial Research Associate Professor Director of the Advanced Education Program in Periodontics University of Iowa College of Denistry and Dental Clinics Ashutosh Mangalam, PhD Professor of Pathology Interdisciplinary Graduate Program in Molecular Medicine University of Iowa Carver College of Medicine Financial Disclosures:  Dr. Gerard Clancy, his guests, and Rounding@IOWA planning committee members have disclosed no relevant financial relationships. Nurse: The University of Iowa Roy J. and Lucille A. Carver College of Medicine designates this activity for a maximum of 1.00 ANCC contact hour. Physician: The University of Iowa Roy J. and Lucille A. Carver College of Medicine designates this enduring material for a maximum of 1.00 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Other Health Care Providers: A certificate of completion will be available after successful completion of the course. (It is the responsibility of licensees to determine if this continuing education activity meets the requirements of their professional licensure board.) References/Resources:  Shahi SK, Ghimire S, Jensen SN, Lehman PC, Rux AG, Sinha S, Borcherding N, Tanas MR, Gibson-Corley KN, Ganesan SM, Karandikar NJ, Mangalam AK. IL-17A deficiency in HLA-DR3 transgenic mice enriches beneficial Prevotella species in gut to promote Tregs and reduce CNS autoimmunity. Microbiome. 2026 Jun 29;14(1):176. doi: 10.1186/s40168-026-02394-w. PMID: 42374500 Lehman PC, Ghimire S, Price JD, Ramer-Tait AE, Mangalam AK. (2023) Diet-microbiome-immune interplay in multiple sclerosis: Understanding the impact of phytoestrogen metabolizing gut bacteria. Eur J Immunol. Nov; 53(11):e2250236. DOI: 10.1002/eji.202250236. PMID: 37673213. Mendoza-Leon MJ, Mangalam AK, Regaldiz A, Gonzalez-Madrid E, Rangel-Ramirez MA, Alvarez-Mardonez OA, Vallejos OP, Mendez C, Bueno SM, Melo-Gonzalez F, Duarte Y, Opazo MC, Kalergis AM, Riedel CA. (2023) Gut microbiota short-chain fatty acids and their impact on the host thyroid function and diseases. Front Endocrinol (Lausanne). Jun 30; 14:1192216. DOI: 10.3389/fendo.2023.119226. PMID: 37455925. PMCID: PMC10349397.

The Swing Riots took place in eastern and southern England in the years between the Luddite uprising and the Rebecca Riots. One of the hallmarks of the riots was the destruction of threshing machines – but that’s just part of the story. Research: Caprettini, Bruno and Hans-Joachim Voth. “Rage Against the Machines: Labor-saving Technology and Unrest in England, 1830-32.” American Economic Review: Insights. Vol. 2, no. 3, September 2020. https://pubs.aeaweb.org/doi/pdfplus/10.1257/aeri.20190385 Carl J. Griffin, “Luddism, Machine-Breaking and the Swing Riots”, Revue Française de Civilisation Britannique [Online], XXX-1 | 2025, Online since 13 January 2025, connection on 14 April 2026. URL: http://journals.openedition.org/rfcb/12984 ; DOI: https://doi.org/10.4000/133dc Chiltern Open Air Museum. “What were the Swing Riots?” https://www.coam.org.uk/blogs/swing-riots Cobbett, William. “Selections from Cobbett's political works : being a complete abridgment of the 100 volumes which comprise the writings of ‘Porcupine’ and the ‘Weekly political register.’” London. Anne Cobbett. 1835. Dyck, Ian. "Cobbett, William (1763–1835), political writer and farmer." Oxford Dictionary of National Biography. September 23, 2004. Oxford University Press. Date of access 22 Jul. 2026, https://www.oxforddnb.com/view/10.1093/ref:odnb/9780198614128.001.0001/odnb-9780198614128-e-5734 Griffin, Carl J. “Swing, Swing Redivivus, or Something After Swing? On the Death Throes of a Protest Movement, December 1830-December 1833.” International Review of Social History. Vol. 54, No. 3. December 2009. https://www.jstor.org/stable/44583279 Griffin, Carl J. “The Violent Captain Swing?” Past & Present, Nov. 2010. Via JSTOR. https://www.jstor.org/stable/40960936 Hampshire History. “The Swing Riots in Hampshire.” https://www.hampshire-history.com/the-swing-riots/ History Hub. “William Cobbett: a champion of the rural poor and the reform of Parliament | Documentary.” YouTube. 10/22/2021. https://www.youtube.com/watch?v=tWO4wjfqJBw Jones, Peter. “Finding Captain Swing: Protest, Parish Relations, and the State of the Public Mind in 1830.” International Review of Social History. Vol. 54, No. 3. December 2009. Via JSTOR. http://www.jstor.com/stable/44583278 Kellett, Ian. “’Swing’ Rioters Smash Machinery at Pythouse near Tisbury.” Shaftesbury Gold Hill Museum. https://goldhillmuseum.org.uk/swing-rioters-smash-machinery-at-pythouse-near-tisbury/ Navickas, Katrina. “Captain Swing in the North: the Carlisle Riots of 1830.” History Workshop Journal. No. 71. Spring 2011. https://www.jstor.org/stable/41306809 Navickas, Katrina. “Rural Resistance and the Swing Riots.” Protest and the Politics of Space. http://protesthistory.org.uk/moors/rural-resistance-and-the-swing-riots Randall, Adrian. “‘The Luddism of the poor’: Captain Swing, machine breaking and popular protest.” Southern History, 32, 2010, pp. 41-61. Randall, Adrian. “Captain Swing: A Retrospect.” International Review of Social History. Vol. 54, No. 3. December 2009. Via JSTOR. https://www.jstor.org/stable/44583277 Wells, Roger. “Mr William Cobbett, Captain Swing, and King William IV.” Agricultural History Review, Volume 45 Part 1 (1997), pp. 34–48. https://www.bahs.org.uk/AGHR/ARTICLE.html?ID=439&MOD=this See omnystudio.com/listener for privacy information.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-497 Overview: While the 2026 ACC/AHA dyslipidemia guidelines may seem overwhelming, we've got you covered. Join us as we walk through the latest recommendations—from risk calculation to treatment targets to testing—and take a close look at the rationale behind the guidelines, so you can guide patients with confidence. Episode resource links: JACC. Published online March 13, 2026. doi: 10.1016/j.jacc.2025.11.016 NEJM: 2026;394:1365-1375 DOI: 10.1056/NEJMoa2600283 JAMA. 2022;328(8):754–771. doi:10.1001/jama.2022.12138 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

Welcome to the latest episode (August 2026) of DOC Updates, where every month Neil Skolnik, MD and John Russell, MD review the most important articles on diabetes, obesity, and cardiometabolic disease. This month on DOC Updates: Hirsh Elhence, Jennifer L. Dodge, Stephen Fuest, et al. National Prevalence of Clinical Obesity by BMI Class: A National Cross-Sectional Study. Ann Intern Med. [Epub 2 June 2026]. doi:10.7326/ANNALS-25-05287 Eva Johnsen, et al. Achieving at Least 15% Weight Loss Within 2 Years of Type 2 Diabetes Diagnosis Is Associated With Lower Risks of Macrovascular and Microvascular Complications: A U.K. Cohort Study. Diabetes Care 20 July 2026; 49 (8): 1480–1489. doi.org/10.2337/dc26-0937 Carel W. le Roux, et al. Survodutide Once Weekly for the Treatment of Adults with Obesity. The New England Journal of Medicine June 2026 DOI: 10.1056/NEJMoa2600751 Yu Wang, Shichao Tang, Xilin Zhou, Ping Zhang. National Trends in Out-of-Pocket Cost for Glucose-Lowering Drugs Among U.S. Adults With Diabetes, 2000–2022. Diabetes Care 20 July 2026; 49 (8): 1414–1419. https://doi.org/10.2337/dc25-2040 Jelle M. Beernink, et al. Effect of Finerenone on Albuminuria in Type 1 Diabetes by Baseline HbA1c Level and Diabetes Duration: An Exploratory Analysis of the FINE-ONE Trial. Diabetes Care 20 July 2026; 49 (8): 1434–1441. https://doi.org/10.2337/dc26-0882 Welch M, Forst T, Jia W et al. Orforglipron compared with dapagliflozin in adults with type 2 diabetes and inadequate glycaemic control with metformin (ACHIEVE-2): a multicentre, randomised, non-inferiority, open-label, phase 3 trial. The Lancet, 2026; 408, 125-140 DOI: 10.1016/S0140-6736(26)00800-7 Presented by: Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Chair-Department of Family Medicine, Abington Jefferson Health DOC Updates is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association's three science and medical journals—Diabetes, Diabetes Care, and Diabetes, Obesity, and CardioMetabolic CARE. Intended for practicing physicians and health care professionals, DOC Updates discusses how the latest research is relevant in clinical practice. For information about the American Diabetes Association's scholarly journals, visit diabetesjournals.org. For more about this podcast, click here.

Credits: 0.25 AMA PRA Category 1 Credit™   CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-497 Overview: While the 2026 ACC/AHA dyslipidemia guidelines may seem overwhelming, we've got you covered. Join us as we walk through the latest recommendations—from risk calculation to treatment targets to testing—and take a close look at the rationale behind the guidelines, so you can guide patients with confidence. Episode resource links: JACC. Published online March 13, 2026. doi: 10.1016/j.jacc.2025.11.016 NEJM: 2026;394:1365-1375 DOI: 10.1056/NEJMoa2600283 JAMA. 2022;328(8):754–771. doi:10.1001/jama.2022.12138 Guest: Robert A. Baldor MD, FAAFP   Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com  The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.

BUFFALO, NY – August 10, 2026 – A new #research paper was #published in Volume 17 of Oncotarget on August 7, 2026, titled “Delayed growth of SK-ES-1 Ewing sarcoma tumor xenografts is associated with reduced Trk and IGF1R pathway markers.” The study was led by first author Bruna Almeida dos Santos and corresponding author Caroline Brunetto de Farias, primarily affiliated with the Federal University of Rio Grande do Sul and the National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology (INCT BioOncoPed), with de Farias also affiliated with the Children's Cancer Institute (ICI) in Brazil. The research team investigated whether targeting tropomyosin receptor kinase (Trk) and related signaling pathways could interfere with Ewing sarcoma growth. Ewing sarcoma is an aggressive cancer that primarily affects children and adolescents and can arise in bone or soft tissue. Although modern multimodal treatments have substantially improved outcomes for patients with localized disease, the prognosis remains considerably poorer for metastatic or relapsed Ewing sarcoma. This has driven efforts to identify molecular pathways that could provide additional therapeutic targets. One potential target involves the Trk family of receptor tyrosine kinases. TrkA, TrkB, and TrkC are encoded by the NTRK1, NTRK2, and NTRK3 genes, respectively, and regulate intracellular signaling pathways involved in cell survival, differentiation, and growth. Previous work from the research group showed that TrkA and TrkB are expressed in Ewing sarcoma and that blocking these receptors can reduce tumor-cell proliferation. Full press release - https://www.oncotarget.com/news/pr/trk-and-igf1r-related-signaling-linked-to-delayed-ewing-sarcoma-growth/ DOI - https://doi.org/10.18632/oncotarget.28911 Correspondence to - Caroline Brunetto de Farias - cbfarias@zielbiosciences.com Abstract video - https://www.youtube.com/watch?v=ZG-vhYfHjuw Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28911 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, Ewing sarcoma, K252a, Trk, NTRK, insulin-like growth factor 1 receptor To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Colorectal cancer does not develop in isolation. Cancer cells exist within a complex tumor microenvironment made up of fibroblasts, immune cells, blood vessels, and extracellular matrix. Increasing evidence suggests that these surrounding cells and structures can influence whether tumors grow, regress, or evade the immune system. A research paper published in Volume 17 of Oncotarget, titled “Microenvironmental CTHRC1 has a pro-tumorigenic role in colorectal cancer,” investigated the role of collagen triple helix repeat containing 1 (CTHRC1), a secreted protein found in cancer-associated stroma. Full blog post - https://www.oncotarget.org/2026/08/10/cthrc1-in-the-tumor-microenvironment-drives-colorectal-cancer-growth-in-mouse-study/ DOI - https://doi.org/10.18632/oncotarget.28878 Correspondence to: Sergey Ryzhov - Sergey.Ryzhov@mainehealth.org; Volkhard Lindner- Volkhard.Lindner@mainehealth.org; Michaela R. Reagan - Michaela.Reagan@mainehealth.org Abstract video - https://www.youtube.com/watch?v=gTbYy6vGd7E Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28878 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, Cthrc1, CRC, colorectal cancer, subcutaneous tumor model, immune analysis To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Today, we are taking a deep dive into an intervention that almost every labor and delivery unit in North America has adopted over the last decade: Quantitative Blood Loss, or QBL. ACOG first recommended quantitative blood loss assessment in Committee Opinion Number 794, published in December 2019. This opinion recommended that every birthing facility implement a standardized, quantitative method for measuring cumulative blood loss at all deliveries, replacing visual estimation as the default approach. This built on earlier ACOG efforts, including the 2015 reVITALize initiative, which standardized obstetric data definitions and defined postpartum hemorrhage using cumulative measured blood loss thresholds (≥1,000 mL regardless of delivery route, or blood loss accompanied by signs/symptoms of hypovolemia). We've all weighed sponges, measured calibrated drapes, and run the math. But here's the million-dollar question: Does measuring blood loss accurately, on its own, actually improve outcomes for patients? The answer is YES….and NO at the same time. Listen in for details as we discuss new data (July 2026 in AJOG) on this topic. 1. White A, Burns RN, Pruszynski JE, Ravindra D, Fin KX, Montgomery T, Jestes E, Ambia AM, Anyaehie B, Duryea EL. Establishing Normal Blood Loss Thresholds at the Time of Delivery Based on Quantitative Blood Loss. Am J Obstet Gynecol. 2026 Jul. DOI: 10.1016/j.ajog.2026.07.028. S0002-9378(26)00395-9. YMOB 16849.2. Quantitative Blood Loss in Obstetric Hemorrhage: ACOG COMMITTEE OPINION, Number 794.Obstetrics and Gynecology. 2019. Committee on Obstetric Practice3. Coomarasamy A, Devall AJ, Bell S, et al. Diagnosis and Treatment of Postpartum Haemorrhage: A Race Against Time. Lancet. 2026.

Quelle est la plus vieille invention entre le papier, la géométrie et l'esclavage ? Sans surprise, l'esclavage est le grand gagnant, étant apparu comme l'écriture durant le Néolithique. Depuis le temps, il y a eu beaucoup de révoltes d'esclaves, dont certaines qui ont marqué l'Histoire, comme Spartacus. Mais aujourd'hui, pas d'Antiquité, pas d'Empire romain, on va partir au Brésil et parler de la plus longue révolte d'esclaves de la colonisation de l'Amérique : le quilombo de Palmares !Bonne écoute !

In the second edition of 'Quarterly catch-up', CMI Communications editors Emily McDonald and Erin McCreary round-up the biggest news in infectious diseases and review clinical microbiology and infectious diseases studies published in the second quarter of 2026 [1-4]. From Pneumocystis jirovecii pneumonia in solid-organ-transplant recipients to a double-blind randomised controlled trial reporting a new antibiotic for complicated urinary tract infections, Erin and Emily highlight four articles they found particularly noteworthy, and comment on whether the results can and should change clinical practice.  ReferencesAlanio A, et al. Pneumocystis jirovecii pneumonia in solid organ transplant recipients: a prospective observational cohort study, J Infect 2026. DOI: 10.1016/j.jinf.2026.106794Ramendra R, et al. Procalcitonin to guide 7 versus 14 days of antibiotics in bloodstream infections: a secondary analysis of the BALANCE trial, JAMA Netw Open 2026. DOI: 10.1001/jamanetworkopen.2026.20973Pai MP, et al. Challenging weight-tiered antibiotic prophylaxis in obese patients undergoing colorectal surgery using CT-derived body composition, CID 2026. DOI: 10.1093/cid/ciag383 Takahashi S, et al. Efficacy and safety of cefepime–nacubactam and aztreonam–nacubactam compared with imipenem–cilastatin for complicated urinary tract infection or acute uncomplicated pyelonephritis (Integral-1): a double-blind, randomised phase 3 trial. Lancet 2026. DOI: 10.1016/S0140-6736(26)00596-9 Further readingThe SNAP Trial Group. Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia. NEJM 2026. DOI: 10.1056/NEJMoa2506905The SNAP Trial Group. Benzylpenicillin versus flucloxacillin or cloxacillin for the treatment of penicillin-susceptible Staphylococcus aureus bacteraemia (SNAP): an international, multicentre, open-label, non-inferiority randomised controlled trial. Lancet 2026. DOI: 10.1016/S0140-6736(26)00761-0McCreary EK, et al. Communicable episode 26: SNAP out of it – rethinking anti-staphylococcal penicillins for S. aureus bacteremia, the SNAP trial PSSA/MSSA results. Communicable Podcast 2025. https://share.transistor.fm/s/2a3c3bb4  Ilges D, et al. Anticalcitonin: limited utility of a context-dependent biomarker demonstrated in another real-world data set, CID 2026. DOI: https://doi.org/10.1093/cid/ciag396 Spellberg B. Procalcitonin–An enigmatic anxiolytic biomarker, JAMA Netw Open 2026. DOI: 10.1001/jamanetworkopen.2026.20978 

Hallie C. Prescott, MD, MSc, joins CHEST® Journal Podcast Moderator Alice Gallo De Moraes, MD, FCCP, to discuss her research into the impact of timely antibiotic delivery and fluid resuscitation on discharge to home after sepsis. DOI: 10.1016/j.chest.2026.03.002 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.  

Astronomy Daily · S05E161 · “The Colour of Empty Space” · Friday 7 August 2026. Hosts: Anna & Avery. astronomydaily.io · @AstroDailyPod ① Vacuum birefringence: reading a magnetar ●        NASA's IXPE, with NICER and the Parkes/Murriyang radio telescope (NSW), measured the polarised X-rays of magnetar 1E 1547.0−5408. ●        Result: soft X-ray polarisation ~65% at 2 keV, rising to nearly 80% at some rotation phases — the strongest signal yet of vacuum birefringence, a QED effect predicted by Heisenberg in 1936. ●        The team calls it the “most definitive signal to date,” not a confirmed detection; an April 2026 analysis disputes it under different geometry. Co-leads: Rachael Stewart; Hoa Dinh Thi (Rice); with Marcus Lower (Swinburne). ●        Source: Stewart et al., Nature, 5 Aug 2026 (DOI 10.1038/s41586-026-10859-z); NASA IXPE release. ② Gateway HALO hardware → Lunar Infrastructure Demos ●        NASA and Northrop Grumman are repurposing the HALO module's power, data and avionics into three surface missions — LID-1, LID-2, LID-3. ●        Goal: “survive-the-night” power and thermal tech for the lunar South Pole, where night lasts ~14 Earth days and temperatures plunge below −200 °C. ●        Part of a wider Moon-base update in which four commercial landers reached final qualification testing at once. ●        Source: NASA & Northrop Grumman releases, 4 Aug 2026; Spaceflight Now. ③ New Glenn: the cause is a valve ●        Blue Origin traced the 28 May New Glenn booster explosion (during a pad hot-fire at Cape Canaveral) to the main oxygen valve on one of the seven BE-4 engines. ●        Fix: small, retrofittable valve modifications; return to flight still targeted by year's end. The BE-4 also powers ULA's Vulcan. ●        Source: Blue Origin CEO Dave Limp, 5 Aug 2026; SpaceNews. ④ LINK's de-spin: the fight to save Swift ●        Katalyst Space's LINK robot — tasked with boosting NASA's ageing Swift observatory before re-entry — hit a multi-axis tumble when two of three reaction wheels failed. ●        Using gimballed electric-propulsion thrusters, the team cut the spin from ~9°/s to ~1.47°/s on under 100 g of propellant. A flight-software update is next; rendezvous slips to ~end of August. ●        Source: NASA Swift blog, 6 Aug 2026; Katalyst mission updates. ⑤ Skywatch: eclipse + Perseids ●        12 Aug total solar eclipse — totality across Greenland, Iceland, northern Spain; afternoon partial for eastern Canada and the NE United States (>10% only NE of the NYC–Rochester line; ~50% in Atlantic Canada). NASA live from 1:15 pm EDT. ●        Perseid peak the night of 12–13 Aug under a New Moon — up to ~100/hr from dark rural sites. ●        Southern Hemisphere: eclipse not visible; Perseids barely clear the horizon. Sydney: pre-dawn planet line-up + Venus + winter Milky Way. ●        EYE SAFETY: use only ISO 12312-2 eclipse glasses for every partial phase; never combine them with a camera, telescope or binoculars.  Become a supporter of this podcast: https://www.spreaker.com/podcast/astronomy-daily-latest-space-news--5648921/support.Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.astronomydaily.io/nordvpn. You'll be glad you did!Get the best secure and private email on the planet. Stop your Government, google and who knows who else spying on every email you write. Do what we did and use ProtonMail. They beleive in privacy and there are no ads in their business model...yet they still provide a free forever service. Check them out and get out special deal at www.astronomydaily.io/protonmailBecome a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click way... Click HereThis episode includes AI-generated content.

Jean Nachega is a professor of infectious diseases and the director of the Biomedical Research Institute at Stellenbosch University and an associate professor at the University of Pittsburgh School of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A. Zumla and Others. Ebola at 50 — Lessons for Outbreak Response and Preparedness. N Engl J Med 2026;395:527-529. S. Tonen-Wolyec and L. Bélec. The Social Contract of Bundibugyo Ebola Isolation. N Engl J Med. DOI: 10.1056/NEJMp2607429.

Barbara Christine Weckler, MD, joins CHEST® Journal Podcast Moderator Alice Gallo De Moraes, MD, FCCP, to discuss her research into the association between admission blood eosinophil counts and hospital resource utilization among adults with community-acquired pneumonia.   DOI: 10.1016/j.chest.2026.03.018 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.

"It's too late" is a feeling, not a fact, and most of the deadlines we're measuring ourselves against were never ours to begin with. In this episode, Brett breaks down why the voice telling you your window has closed is working from bad information, and gives you a three-question "ownership test" for telling a real constraint from an inherited story, so you can find out whether the change you keep circling is actually worth making. What You'll Learn in This Episode Why the feeling that it's too late is not evidence that it's too late — and the specific blind spot in how our minds predict our own future selves The 2013 "End of History Illusion" study and what it reveals about why every age group believes they're basically done changing The difference between a real constraint and a borrowed deadline you absorbed from comparison, family expectation, or culture — and never agreed to Why "is it too late?" is actually two different questions wearing the same coat, and why only one of them deserves a factual answer The Ownership Test: three questions to separate a change that's genuinely yours from one that's just an escape Why the regret of the untried tends to outlast the regret of things that didn't work out The smallest honest step you can take this month to turn "too late" from a story you obey into a fact you check Episode Timestamps [0:00] Introduction — the version of your life you keep circling [2:00] Why "too late" feels so convincing, even when it's wrong [4:00] The End of History Illusion — the 2013 study on how badly we predict our own change [7:00] Borrowed deadlines — where your "too late" clock actually comes from [8:00] Julia Child and the myth of the linear timeline [10:00] Separating real constraints from inherited stories [11:00] Moving toward vs. running from — why the same decision can mean two different things [13:00] The Ownership Test — three questions to run any change through [16:00] Why the regret of the untried outlasts the regret of trying [17:00] This week's smallest honest step Episode Summary There's a version of your life you keep circling back to. Different work, a creative thing you set down years ago, a move, a different way of being in your own days. And every time it comes close, a quiet voice forecloses it: "Nice idea, but that ship's already sailed." Brett opens this episode by taking that voice seriously instead of arguing with it — and then taking it apart. The central claim of the episode is simple and, once you hear it, hard to unhear: "The feeling that it's too late is not evidence that it's too late." Those are two different things, and we habitually treat them as one. To back this up, Brett walks through a 2013 study published in Science by psychologists Jordi Quoidbach, Daniel Gilbert, and Timothy Wilson, called "The End of History Illusion." Researchers surveyed more than 19,000 people ages 18 to 68 and asked how much they'd changed over the past decade versus how much they expected to change over the next one. At every single age, people readily admitted they'd changed a lot in the past — and then predicted they'd barely change going forward. In other words, no matter how old you are, there's a persistent illusion that right now is the moment you've finally become who you're going to be. If that's true at every age, the person telling you "it's too late for me to become someone different" is very likely making the exact predictable error the whole species makes. That's the first thing "too late" gets wrong: it assumes you're finished. The second thing is about the clock itself. Most of the deadlines we carry — established in your 20s, settled by your 30s, peaked in your 40s — aren't real deadlines. They're borrowed ones, absorbed from peer comparison, family expectation, and culture, never consciously chosen. Brett illustrates this with Julia Child, who didn't cook seriously until her late 30s, trained in France at 36, and published the cookbook that made her a household name at 49. Measured against the timeline most of us carry, she'd have been called finished. It would have been wrong. Here's where the episode does its most useful work. Brett argues that "is it too late?" isn't one question — it's two, wearing the same coat, and they need different answers. The first is the constraint question: is this change actually still possible, physically and practically? That deserves a clear-eyed factual answer, not a feeling. The second is the ownership question, and it's the one almost nobody asks: is this change mine? Are you moving toward something that genuinely fits who you're becoming, or just trying to escape something that hurts right now? Two motivations that feel identical in the moment but lead to completely different places — because a change built only on escape tends to rebuild the same problem somewhere new. From there, Brett offers what he calls the ownership test: three questions to run any change you're circling through. The constraint question (what specifically is in the way, and have you actually inspected the wall or just assumed it's there?), the ownership question (finish the sentence "I want this change because ___" and notice whether you're moving toward something or away from something), and the cost-of-not question (what does it quietly cost you in five years if you never touch this at all?). The point isn't to talk you into changing — it's to make the choice yours instead of the fear's. And the research on regret backs this up: people tend to make peace with things they tried that didn't work out. What sits heaviest years later is the door they never walked up to at all. This idea sits at the center of what optYOUmize means by growth — not a checklist of habits or a race against a timeline, but the slower, more honest work of closing the gap between how your life looks and how it actually fits. If this episode resonated, that's the deeper territory to explore next. The takeaway Brett leaves you with: this week, do exactly one honest thing with the change you keep circling. Not the leap — just the inspection. Walk up and touch the wall you've been describing from across the room. Resources Mentioned "The End of History Illusion" — Jordi Quoidbach, Daniel T. Gilbert, and Timothy D. Wilson, Science, Vol. 339, Jan. 4, 2013 — DOI: 10.1126/science.1229294 Julia Child — chef and author who didn't train professionally until her late 30s — en.wikipedia.org/wiki/Julia_Child The Shawshank Redemption — referenced for the line "Get busy living, or get busy dying" Frequently Asked Questions Is it actually too late to change your life? Usually not — but the honest answer depends on separating two different questions. Whether a specific change is still physically or practically possible deserves a factual answer, not a feeling. Whether the change is genuinely yours to make (versus an inherited deadline you never agreed to) is the question most people never actually ask. What is the "End of History Illusion"? It's a finding from a 2013 study in Science (Quoidbach, Gilbert, and Wilson) showing that people at every age readily admit they've changed a lot in the past decade, but consistently predict they'll barely change in the next one. The researchers concluded people tend to treat the present as a kind of finish line for who they'll become — a belief the data shows is reliably wrong at every age. How do I know if a deadline I'm holding myself to is real or just something I absorbed? Ask where it actually came from. Most "too late" deadlines trace back to peer comparison, family expectation, or a cultural script (established in your 20s, settled by your 30s) rather than any genuine constraint. A real constraint is something you can name specifically — a dollar amount, a skill gap, an obligation to a real person. If you can't name the specific obstacle, it's likely a borrowed story rather than a wall. What is the "ownership test" from this episode? It's a three-question framework for deciding whether a change you're circling is genuinely yours to make: the constraint question (what's factually in the way, and have you actually inspected it?), the ownership question (are you moving toward something or escaping something?), and the cost-of-not question (what does staying the same quietly cost you in five years?). What's the difference between making a change to move toward something versus to escape something? Both can look identical from the outside — quitting a job, for example — but internally one is a compass and the other is a fire alarm. A change built primarily on escaping discomfort tends to recreate the same problem in a new location, because part of what you didn't like was inside the situation and part was inside you. A change built on moving toward something specific tends to be more durable. Do people regret the changes they tried that didn't work out? Research on regret suggests people tend to make peace with things they tried, even when they didn't land the way they'd hoped. What tends to weigh heaviest years later is the door someone never walked up to check at all — the regret of the untried, which is a distinct and more durable kind of regret. What's the smallest step I can take if I'm not ready to make a big change? Brett's advice is to skip the leap and start with the inspection. Take the change you keep circling and do one honest, small thing to test it this month — a class, a conversation, one experiment — small enough that "too late" becomes a fact you check instead of a story you obey. Keep Exploring If this episode resonated, these are worth your time: Growth & Self-Becoming — The optYOUmize pillar page on growing in the direction of your own values instead of a borrowed timeline → https://optimizeyoumize.com/growth-self-becoming/ Enjoyed This Episode? The best way to support optYOUmize is to subscribe and leave a review — it takes about two minutes and makes a real difference in helping more people find the show. Apple Podcasts · Spotify · Amazon Music · YouTube Leave a Review →

Heat waves don’t get as much attention as blizzards, floods, and hurricanes, but extreme heat is one of the deadliest weather events on average. Research: National Weather Service. “Weather Related Fatality and Injury Statistics.” https://www.weather.gov/hazstat Last, John. “This Summer’s Drought Is Europe’s Worst in 500 Years. What Happened Last Time?” Smithsonian Magazine. 9/8/2022. https://www.smithsonianmag.com/history/this-summers-drought-is-europes-worst-in-500-years-what-happened-last-time-180980711/ Wetter, Oliver; Seneviratne, Sonia I. et al. “The year-long unprecedented European heat and drought of 1540 - a worst case.” Climatic Change 125(3-4), https://doi.org/10.1007/s10584-014-1184-2 Orth, Rene et al. “Did European temperatures in 1540 exceed present-day records?” Environmental Research Letters. 11 (2016) 114021 doi:10.1088/1748-9326/11/11/114021. United Nations Environment Programme. “Impacts of summer 2003 heat wave in Europe.” Environmental Alert Bulletin. https://www.unisdr.org/files/1145_ewheatwave.en.pdf Pfister, Christian. “The ‘Black Swan’ of 1540: Aspects of a European Megadrought.” From Climate Change and Cultural Transition in Europe. Brill. 1/1/2018. doi:10.1163/9789004356825_007 Grodzinsky, Ewa, and Märta Sund Levander. “History of the Thermometer.” Understanding Fever and Body Temperature: A Cross-disciplinary Approach to Clinical Practice 23–35. 23 Aug. 2019, doi:10.1007/978-3-030-21886-7_3 John Huxham, Dr. Watson. “Remarks upon the Heat of the Air in July 1757. in an Extract of a Letter from John Huxham, M. D. F. R. S. to William Watson, M. D. F. R S. Dated at Plymouth 19th of That Month. With Additional Remarks by Dr. Watson.” Philosophical Transactions (1683-1775), Vol. 50 (1757 - 1758), pp. 428-430 (3 pages). Via JSTOR. https://www.jstor.org/stable/105279. Huxham, John. “An Account of the Extraordinary Heat of the Weather in July 1757, and of the Effects of It. In a Letter from John Huxham, M. D. F. R. S. to Wm. Watson, M. D. F. R. S..” Philosophical Transactions (1683-1775), Vol. 50 (1757 - 1758). Via JSTOR. https://www.jstor.org/stable/105292 Smeaton, John. “Remarks on the Different Temperature of the Air at Edystone, from That Observed at Plymouth, between the 7th and 14th of July 1757. By Mr. John Smeaton, F. R. S.” Philosophical Transactions (1683-1775), Vol. 50 (1757 - 1758). https://www.jstor.org/stable/105286 Sunderland, Helen. “The Great British Summer? A Historical Heatwave.” Doing History In Public. 8/12/2025. https://doinghistoryinpublic.org/2025/08/12/the-great-british-summer-a-historical-heatwave/ Scott, John. “Four elegies, descriptive and moral.” London J. Buckland. 1760. The Western Flying Post; or, Sherborne and Yeovil Mercury. Page 3. 8/15/1757. Lind, James. “An essay on the most effectual means of preserving the health of seamen in the Royal Navy.” 1774. Walpole, Horace. “The letters of Horace Walpole, fourth earl of Orford.” Vol. 3: 1750-1756. Oxford. 1903. Zwierlein, Cornel. "Chapter 3 The Danger between Nature and Culture: The Quotidian Threat of Urban Fires in the Premodern Era". Prometheus Tamed. Leiden, The Netherlands: Brill, 2021. https://doi.org/10.1163/9789004431225_004 Web. Luterbacher, Jürg et al. “European Seasonal and Annual Temperature Variability, Trends and Extremes since 1500.” Science 303, 1499 (2004). DOI: 10.1126/science.1093877 Beniston, Martin. “The 2003 heat wave as an example of summers in a greenhouse climate? Observations and climate model simulations for Basel, Switzerland.” Global and Planetary Change. Volume 44, Issues 1–4, December 2004. https://www.sciencedirect.com/science/article/abs/pii/S0921818104000980 Franck, Marcy. “Heat waves and annual death rates in older adults in the United States.” Harvard T.H. Chan School of Public Health. 3/16/2026. https://hsph.harvard.edu/news/heat-waves-and-annual-death-rates-in-older-adults-in-the-united-states/ Poitras, Colin. “Warming U.S. climate linked to rising deaths from heat.” Yale School of Public Health. 11/7/2025. https://ysph.yale.edu/news-article/warming-us-climate-linked-to-rising-deaths-from-heat/ World Meteorological Association. “Western Europe has hottest June on record.” 7/9/2026. https://wmo.int/media/news/western-europe-has-hottest-june-record Cole, Deborah. “Germany records nearly 100 drowning deaths, many of them young men, in June heatwave.” The Guardian. 6/12/2026. https://www.theguardian.com/world/2026/jul/12/germany-drowning-deaths-heatwave-paris-france-spain PBS News. “Europe swelters under an early heat wave as France records 40 drowning deaths.” 6/23/2026. https://www.pbs.org/newshour/world/europe-swelters-under-an-early-heat-wave-as-france-records-40-drowning-deaths See omnystudio.com/listener for privacy information.

Heart failure remains one of the leading causes of hospitalization among older adults worldwide. During episodes of acute decompensated heart failure (ADHF), excess fluid builds up in the lungs and body, making breathing difficult and increasing the risk of serious complications. Although intravenous loop diuretics such as furosemide are the standard treatment for relieving congestion, many patients continue to experience persistent inflammation, ongoing cardiac remodeling, and worsening heart function despite therapy. A research paper published in Volume 18 of Aging titled “Effects of intravenous furosemide plus small-volume hypertonic saline solutions on inflammatory, remodelling markers and epigenetics signatures of patients with congestive acute decompensated heart failure (ADHF),” investigated whether combining intravenous furosemide with small volumes of hypertonic saline solution (HSS) could improve biological markers associated with heart failure compared with furosemide alone. Full blog post - https://aging-us.org/2026/08/hypertonic-saline-plus-furosemide-improves-heart-failure-biomarkers-in-randomized-trial/ DOI - https://doi.org/10.18632/aging.206364 Corresponding author - Antonino Tuttolomondo - bruno.tuttolomondo@unipa.it Abstract video - https://www.youtube.com/watch?v=EG65XlcDJ3U Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206364 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, heart failure, acute decompensated heart failure, furosemide, hypertonic saline solution To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Who is J.T. Welsch? J. T. Welsch is a writer and academic born in the US andbased in the UK, where he teaches at the University of York. He is the author of several books of and about poetry, including Orchids (2010), The Hell Creek Anthology (2015) and The Selling and Self-Regulation of Contemporary Poetry (2020). He also edited the anthology of migrant poetry Wretched Strangers (2018) with Ágnes Lehóczky. His writing has appeared in Poetry Review, Boston Review and the Guardian. In this episode hear about his new book on The Poetry of Suicide: Lessons in grief from the lives and deaths of poets. In the episode introduction, you heard from: Joshua Hurtado Hurtado, PhD, University of Helsinki and Jason Glynos, Professor at the Department of Government, University of Essex about their new article, "Thanabots, fantasy, and theethics of mourning", published in AI & Society. You can find ithere: https://link.springer.com/article/10.1007/s00146-026-03200-9  And then Dr. Mórna O'Connor on her and Dr Dorthe Refslund Christensen's new collection, Creative and Aesthetic Ways of Grief: "All Things Reimagined".How do I cite the episode in my research and reading lists?To cite this episode, you can use the following citation: Welsch, J.T. (2026) Interview on The Death Studies Podcast hosted by Michael-Fox, B. and Visser, R. Published 1 August 2026. Available at: www.thedeathstudiespodcast.com, DOI: 10.6084/m9.figshare.33129308What next?Check out more ⁠episodes⁠ or find out more about the ⁠hosts! ⁠Gota question? ⁠Get in touch⁠.

Photo: Santa Fe Indian School campus. (Courtesy Administration for Native Americans for Children & Families) U.S. Rep Melanie Stansbury (D-NM) introduced two bills this week to modernize the Bureau of Indian Education (BIE) and potentially bring higher teacher salaries and more federal funding for tribal schools. KUNM's Jeanette DeDios (Jicarilla Apache and Diné) has more. The Indigenous Students Excel through Parity Act and its supporting Act II bill would create a study under the Department of Interior (DOI) to recommend reforms in order to provide funds that could increase teacher pay, and provide more educational opportunities. An identical bill is sponsored in the Senate by U.S. Sens. Martin Heinrich (D-NM) and Cynthia Lummis (R-WY). DOI administers BIE, which funds 183 schools across the country. New Mexico has one of the highest concentrations of BIE-funded schools with 44. Despite this, Rep. Stansbury says BIE schools have traditionally been underfunded, but they are competing with state-funded schools to recruit teachers. “So what this bill would do is study the current formula funds that are allocated per student to these tribally controlled schools to evaluate one how to increase funding per student, how to address increasing teacher and staff pay, and how to make sure that those schools who have extra costs and needs can have their needs met.” Stansbury says the goal of the bills is to bring teacher salaries in tribal schools up to the same level as those in state-funded schools. “If you’re a teacher, I mean, think about it, and you really want to work in a tribal community, whether you are a Native person yourself or not. And you’re looking at the difference of getting paid, let’s say, $50,000 by the federal government versus going and teaching in APS (Albuquerque Public Schools) making $60,000, you know, you’re going to have to make that economic decision for yourself and your family, and so we don’t want teachers to have to make that decision. We want teachers to be teaching in the schools they want to.” The proposed bill does not have a cost included with it, but if the study recommendations are enacted, BIE would have to boost funding for tribal schools. Jaynie Parrish and her father drop off ballots at the one county ballot box in their town of Kayenta, Ariz., left, and members of Arizona Native Vote's Hopi team, the Firekeepers, register younger community members in Bacavi, Ariz. (Photos: Jason Biggs / courtesy Jaynie Parrish) The U.S. Supreme Court recently ruled that mail-in ballots that arrive after Election Day can still be counted. While the move is a win for Arizona’s Indigenous voters, it highlights the challenges Native people still face in rural parts of the state, as Mark Moran reports. Voting rights advocates say the debate highlights the challenges Native people face in trying to submit a ballot in person. The sheer geography, vast distances between physical polling places, and lack of transportation all present obstacles for Indigenous voters. In many places, the nearest polling place may be miles away, but Arizona Native Vote’s Jaynie Parrish says many people on reservations also lack physical addresses, which creates its own set of problems. “Even in some rural towns, they have physical addressing, but not on a lot of Tribal lands. We still predominantly use PO boxes. That means we have to go to a U.S. Post Office or another location to pick up mail, but our folks still vote by mail.” The Trump administration has pushed back on the high court’s ruling, asking justices to allow the president’s executive order to be implemented. The attempt to reject mail-in ballots received after Election Day is among a host of bold policy choices under the Trump administration. Parrish also points to efforts to challenge voter citizenship, which she says hit especially hard on Native reservations. “It’s just absurd. You get a look on people’s face when we have to explain this or when they hear about the news or what this means, and it’s another barrier. And it’s ridiculous to ask First Peoples, Indigenous Peoples of their citizenship.” According to research from the Brennan Center, Indigenous voters were about 7% less likely to cast their ballot by mail in the last General Election, reflecting a wider lack of participation among Natives. Get National Native News delivered to your inbox daily. Sign up for our daily newsletter today. Download our NV1 Android or iOs App for breaking news alerts. Check out today’s Native America Calling episode Thursday, July 30, 2026 — The Menu: food heals in books ‘Our Knives Will Save Us’ and ‘Raven, Rising’

Join @JMusgravePT as he discusses a recent systematic review on how to get the best results from adding cognitive complexity to your client programming! Guan, Li & Bu (2026). Four-Limb Coordinated Training and Neuroplasticity in Older Adults with Cognitive Frailty. Clinical Interventions in Aging. DOI: 10.2147/CIA.S594798 Join MMOA Digest mmoa.online to get more helpful info! 

¿Es posible perder la menstruación aun llevando una vida "saludable" y sin tener un Trastorno de la Conducta Alimentaria (TCA)?La respuesta es sí, y se llama Amenorrea Hipotalámica Funcional (AHF).En el episodio de hoy revisamos en detalle la evidencia científica más reciente (Nutrition Research, DOI: 10.1016/j.nutres.2025.06.008) sobre la AHF en mujeres que no sufren un TCA aparente:Baja Disponibilidad Energética (LEA): Por qué el cuerpo "apaga" el sistema reproductor al detectar un déficit calórico no intencionado o un exceso de gasto energético.El papel de los carbohidratos y el estrés: Cómo la restricción de hidratos o el cortisol alto actúan como señales de alarma para el hipotálamo.Estrategias para recuperar el ciclo: Aumento estratégico de calorías, ajuste en el entrenamiento y el mito de que "no tener la regla es cómodo".Un análisis riguroso para entender que la menstruación es una constante vital de salud en la mujer.

Astronomy Daily S05E154 — “The Reach of a Giant.” Thursday, 30 July 2026. Hosted by Anna and Avery. In this episode •    A supermassive black hole caught heating and stirring an entire galaxy cluster — turbulence reaching ~300,000 light-years, about 100× more energetic than expected (XRISM / quasar H1821+643). •    Why some “clean” white dwarfs are secretly feasting: magnetic fields funnel shredded planetary debris to the poles, aurora-style, hiding the meal. •    NASA's Psyche used its Mars flyby as a dress rehearsal — spotting Phobos and Deimos from afar to practise for its 2029 moonlet hunt at asteroid 16 Psyche. •    A new study on keeping the road to the Moon clear: modelling how debris disperses in Distant Retrograde Orbits as cislunar traffic climbs. •    Skywatch: tonight's double meteor shower — the Southern Delta Aquariids and Alpha Capricornids — with both-hemispheres viewing details and local times. Sources •    Yamada, S. et al., “Vigorous turbulence driven by quasar-mode feedback in a cluster core,” Nature Astronomy, 28 July 2026 (DOI 10.1038/s41550-026-02939-x; arXiv 2607.24911). Tohoku University release. •    “White Dwarfs Eat More Planetary Debris Than Thought, But Magnetic Fields Hide It,” Universe Today, 29 July 2026 (Pham et al., arXiv 2607.20747). •    “NASA's Psyche Spacecraft Aces Mars Flyby,” NASA JPL / ScienceDaily, 28 July 2026. •    “The Risks of Debris Between the Earth and the Moon for Future Exploration,” Universe Today, 29 July 2026 (Chinese Academy of Sciences DRO study). •    Double meteor shower peak: American Meteor Society; NASA; Scientific American; CNN; National Geographic, 28–30 July 2026. Correction / caveat desk •    Skywatch numbers assume the ~98% waning Buck Moon (full 29 Jul). Faint Delta Aquariids will be washed out; the Alpha Capricornid fireballs are the reliable catch tonight.Become a supporter of this podcast: https://www.spreaker.com/podcast/astronomy-daily-latest-space-news--5648921/support.Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.astronomydaily.io/nordvpn. You'll be glad you did!Get the best secure and private email on the planet. Stop your Government, google and who knows who else spying on every email you write. Do what we did and use ProtonMail. They beleive in privacy and there are no ads in their business model...yet they still provide a free forever service. Check them out and get out special deal at www.astronomydaily.io/protonmailBecome a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click way... Click HereThis episode includes AI-generated content.

Nutrition plays a critical role in cancer care, yet it is often overlooked. Many patients experience weight loss, muscle wasting, treatment-related side effects, and changes in appetite that can affect their ability to tolerate therapy and maintain quality of life. Although nutrition specialists can help manage these challenges, access to specialized nutritional care remains limited in many healthcare settings. An editorial published in Volume 17 of Oncotarget, titled “Artificial intelligence in nutritional oncology: From isolated screening tools to agentic intervention systems,” explores how advances in artificial intelligence (AI) could help address this gap. The editorial was written by Arnab Sarkar and corresponding author Yashbir Singh-Wolkenhauer, who is affiliated with the Department of Radiology, Mayo Clinic, Rochester, Minnesota. Rather than presenting new clinical trial data, the authors outline a future vision in which AI systems move beyond isolated tasks to continuously support nutritional care throughout a patient's cancer journey. Full blog post - https://www.oncotarget.org/2026/07/28/artificial-intelligence-could-transform-nutrition-care-for-cancer-patients/ DOI - https://doi.org/10.18632/oncotarget.28874 Correspondence to - Yashbir Singh-Wolkenhauer - singh.yashbir@mayo.edu Abstract video - https://www.youtube.com/watch?v=sVKhRSr5xaY Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28874 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, artificial intelligence To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us on social media: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Astronomy Daily S05E152 — “Reading the Heat” · Tuesday 28 July 2026. Hosts Anna & Avery. NASA's Juno spacecraft has taken the first-ever temperature reading beneath the surface of Io, Jupiter's volcanic moon — and the technique behind it could reshape how we study icy ocean moons and even volcanoes on Earth. We also look at why JWST's “Little Red Dots” might be globular clusters being born, the first SETI search built from archived ALMA data (and its six-million-star surprise), and a live burst of space weather feeding into a meteor-filled — if Moon-washed — skywatch. In this episode ●        Juno reads Io's subsurface temperature for the first time — >20°C rise within a few metres, heat flow up to ~30× Earth's average, and a remarkably smooth, low-density surface. ●        Why the method matters: a multi-depth microwave thermometer that works from orbit — promising for Europa, Enceladus, and terrestrial volcanology. ●        JWST's “Little Red Dots” may be globular clusters in formation, powered by a short-lived supermassive star — linking two long-standing mysteries. ●        The first SETI survey of archived ALMA data opens the millimetre band — and reveals “stellar bycatch” of 6.1 million background stars. ●        Live space weather: an M3.2 flare from region AR4494 and a glancing CME, with G1–G2 storms and possible aurorae, north and south. ●        Skywatch: meteor week under the full Buck Moon (29 July), the Alpha Capricornid fireball tip, evening Venus, pre-dawn Saturn/Mars/Mercury — and Jupiter vanishing behind the Sun. Sources ●        NASA/JPL — “NASA's Juno Takes Temperature of Jupiter's Fiery Moon Io” (22 July 2026); Brown et al., J. Geophys. Res.: Planets, DOI 10.1029/2025JE009622. ●        Chisholm et al., “Little Red Dots as Globular Clusters in Formation,” Astrophysical Journal Letters (press cycle 20 July 2026; UT Austin / McDonald Observatory). ●        L. Mason (University of Manchester), first ALMA-archive SETI survey, RAS National Astronomy Meeting 2026. ●        Space-weather status: EarthSky Sun news / NOAA SWPC (M3.2 flare AR4494, 26 July; 24 July CME; G1–G2 outlook, 27–28 July). ●        Skywatch data: EarthSky, Star Walk, American Meteor Society, NASA — Southern Delta Aquariids (peak ~30 July), Alpha Capricornids (30–31 July), full Buck Moon 29 July, Jupiter solar conjunction 29 July.  Become a supporter of this podcast: https://www.spreaker.com/podcast/astronomy-daily-latest-space-news--5648921/support.Sponsor Details:Ensure your online privacy by using NordVPN. To get our special listener deal and save a lot of money, visit www.astronomydaily.io/nordvpn. You'll be glad you did!Get the best secure and private email on the planet. Stop your Government, google and who knows who else spying on every email you write. Do what we did and use ProtonMail. They beleive in privacy and there are no ads in their business model...yet they still provide a free forever service. Check them out and get out special deal at www.astronomydaily.io/protonmailBecome a supporter of Astronomy Daily by joining our Supporters Club. Commercial free episodes daily are only a click way... Click HereThis episode includes AI-generated content.

What's the episode about? In this episode, hear about an event on Love and Loss: A DayAt Arnos Vale Historic Garden Cemetery, Bristol discussing love, romance, sex, death, culture, prison writing, slow suicide, creative writing, obituaries, epitaphs and more.You will listen to a range of academic research love, romance, death, grief and loss, all based or connected to the South West of England, and many of whom were recorded whilst walking around the rather hilly Arnos Vale Historic Garden Cemetery in Bristol, so do forgive any out of breath-ness!  The day in April 2026 at Arnos Vale began with a networking and idea generation event for researchers, followed by a guided tour open to the public with the theme of love and loss.This was filled with a rich mix of real-life tales — from couples united in life but separated in death, to daring elopements, parental love, and forbidden love. Some stories are touching, some tragic, and some wonderfully surprising.  This was followed by a creative writing workshop on the theme of love and loss, including practical activities and stimulus prompts drawn from the cemetery and the lives of its occupants. The aims of the day were: ●      To provide a forum for constructive discussion & preliminary dissemination of research works in progress.●      To identify potential future collaboration.●      To share research of high public interest with an openaudience in an established heritage setting. Links below for more information on the place and people inthis episode!Find out more about Arnos Vale. Find out more about newly appointed Associate Professor Dr JoParsons. Find out more about Janine Marriott. Find out more about Dr Andrew Griffiths.  A huge thank you to the Open University for their supportfor this event via the Academic Communities Fund!  How do I cite the episode in my research and reading lists?To cite this episode, you can use thefollowing citation: Michael-Fox, B. and Visser, R. (2026) The Death Studies Podcast hosted by Michael-Fox, B. and Visser, R. Published 26 July 2026. Available at: www.thedeathstudiespodcast.com, DOI: 10.6084/m9.figshare.33089351 What next?Check out more episodes or find out more about the hosts! Gota question? Get in touch.

Peter Howitt won the 2025 Nobel Prize in Economic Sciences. The award was for the theory of sustained growth through creative destruction. He and Philippe Aghion gave that theory a mathematical form in 1992.Competition and innovation do not move together in a straight line. What decides the direction is where a firm sits relative to the technological frontier. Peter also draws the line between a merger that buys innovation and one that removes it, and he describes the route by which an incumbent turns market power into political power. We then turn to agent-based modeling. He is candid about why a method he still defends took thirty years to find readers.Follow me on X (https://x.com/profschrepel) and BlueSky (@ProfSchrepel).***References:"A Model of Growth Through Creative Destruction" (with Aghion), Econometrica 60(2), March 1992, 323–351. https://www.jstor.org/stable/2951599.Endogenous Growth Theory (with Aghion), MIT Press, 1998. https://mitpress.mit.edu/9780262528467/endogenous-growth-theory/"Competition and Innovation: An Inverted-U Relationship" (with Aghion, Bloom, Blundell, Griffith), Quarterly Journal of Economics 120(2), May 2005, 701–728. https://academic.oup.com/qje/article-abstract/120/2/701/1933966."The Effects of Entry on Incumbent Innovation and Productivity" (with Aghion, Blundell, Griffith, Prantl), Review of Economics and Statistics 91(1), February 2009, 20–32. https://direct.mit.edu/rest/article/91/1/20/57753/The-Effects-of-Entry-on-Incumbent-Innovation-and."The Emergence of Economic Organization" (with Robert Clower), Journal of Economic Behavior & Organization 41(1), January 2000, 55–84. https://www.sciencedirect.com/science/article/abs/pii/S0167268199000876."Banks, Market Organization, and Macroeconomic Performance: An Agent-Based Computational Analysis" (with Ashraf and Gershman), JEBO 135, March 2017, 143–180. DOI 10.1016/j.jebo.2016.12.023."How Inflation Affects Macroeconomic Performance: An Agent-Based Computational Investigation" (with Ashraf and Gershman), Macroeconomic Dynamics 20(2), March 2016, 558–581. https://www.cambridge.org/core/journals/macroeconomic-dynamics/article/abs/how-inflation-affects-macroeconomic-performance-an-agentbased-computational-investigation/DC3AF3CA750F82FDE20164B36935FA1F."Getting at Systemic Risk via an Agent-Based Model of the Housing Market" (with Geanakoplos, Axtell, Farmer and others), American Economic Review 102(3), May 2012, 53–58. https://www.aeaweb.org/articles?id=10.1257/aer.102.3.53.

In this episode of Communicable, Nav Narayanan and Thomas Tängdén kick off the first 'Ask me anything' episode, inviting EUCAST and CLSI leadership Sören Gatermann, Christian Giske and Amy Mathers to answer questions from our listeners. Together, they discuss the roles and operations of both organisations, similarities and differences between EUCAST and CLSI, how breakpoints and guidance documents are developed, set the record straight about the 'I' category, explain which data inform breakpoint decisions, and much more.This episode was edited by Communicable's executive producer, Angela Huttner. Further readingDocuments/resources:CLSI MicroFree, https://em100.edaptivedocs.net/Login.aspx?ru=1EUCAST: When there are no antifungal breakpointsEUCAST: When there are no breakpoints?Use_of_fosfomycin_iv_breakpoints_General_advice_20240528.pdfEUCAST: Definition of S, I and REUCAST Guidance Document, “When there are no breakpoints”, https://www.eucast.org/bacteria/guidance-documents/EUCAST Guidance Document for “Rare Yeasts”, https://www.eucast.org/fungi-afst/guidance-documents/Articles (alphabetical): Bixby ML, et al. Fosfomycin Disk Diffusion Testing among Klebsiella pneumoniae Results in Frequent Inner Colonies and Categorical Disagreement Based on Conflicting Breakpoint Organization Recommendations. Microbiol Spectr 2023. DOI: 10.1128/spectrum.03363-22DeMarco MG, et al. Impact of media brand on cefiderocol disk diffusion results. J Clin Microbiol 2025. DOI: 10.1128/jcm.01648-24Giske CG, et al. Aminoglycoside breakpoints-the EUCAST approach and what this means for the clinician. CMI 2025. DOI: 10.1016/j.cmi.2025.08.015Mouton JW, et al. MIC-based dose adjustment: facts and fables. J Antimicrob Chemother 2018. DOI: 10.1093/jac/dkx427Narayanan N, et al. Amoxicillin-Clavulanate Breakpoints Against Enterobacterales: Rationale for Revision by the CLSI. Clin Infect Dis 2024. DOI: 10.1093/cid/ciae201Narayanan N, et al. Amoxicillin-Clavulanate Breakpoints Against Enterobacterales: Rationale for Revision by the Clinical and Laboratory Standards Institute. Clin Infect Dis 2024. DOI: Pham Thanh D, et al. A novel ciprofloxacin-resistant subclade of H58 Salmonella Typhi is associated with fluoroquinolone treatment failure. eLife 2016. DOI: 10.7554/eLife.14003.001 Smekal A. Swedish multicentre study of target attainments with β-lactams in the ICU: which MIC parameter should be used? J Antimicrob Chemother 2023. DOI: 10.1093/jac/dkad327Turnidge J, et al. How to: the application and analysis of categorical agreement in antimicrobial susceptibility testing using EUCAST breakpoints. CMI 2026. DOI: 10.1016/j.cmi.2025.12.018Turnidge J, et al. Rationale for contemporary antimicrobial treatment of Stenotrophomonas maltophilia: a narrative review. CMI Comms 2025. DOI: 10.1016/j.cmicom.2025.105082Weinstein M, et al. The CLSI Subcommittee on Antimicrobial Susceptibility Testing: Background, Organization, Functions, and Processes. J Clin Microbiol 2020. DOI: 10.1128/jcm.01864-19

This week we discuss a recent report from the team at SickKids in Toronto on minimally invasive cardiac surgery. What sorts of operations are most common for this approach? Why are length of ICU and length of hospitalization periods lower in this surgical cohort than more traditional midline sternotomy approaches? How does one train a surgeon to perform these operations if the surgical exposure is so small, allowing only the priimary surgeon to see the majority of the surgery? What are the limits of this sort of surgical approach? These are amongst the questions posed to the first author of this work, Associate Professor of Surgery at University of Toronto, Dr. Christoph Haller. DOI: 10.1016/j.jtcvs.2025.12.009

In this episode, Lillian Erdahl, MD, FACS, is joined by Morgan Pettigrew, MD, from UT Southwestern. They discuss Dr Pettigrew's recent article, “Artificial Intelligence Simplification of English and Spanish Surgical Consent Forms: 1-Size Does Not Fit All,” which found that while ChatGPT-4.0 improved the readability of English surgical consent forms, it did not improve readability of Spanish forms. To address this disparity, the authors developed a custom-trained GPT that improved readability of English and Spanish consent forms.   Disclosure Information: All relevant conflicts have been mitigated and Drs Erdahl and Pettigrew, moderators, have no relevant financial conflicts to disclose.   To earn 0.25 AMA PRA Category 1 Credits™ for this episode of the JACS Operative Word Podcast, click here to register for the course and complete the evaluation. Listeners can earn CME credit for this podcast for up to 2 years after the original air date.   Pettigrew, Morgan F MD; Nunez-Rocha, Ricardo E MD; Govindu, Sai R BS; Castillo, Samy MD; Heslin, Ryan T MD; Bain, Andrew P MD; Abreu, Andres A MD; Fatimah, Nafeesah MD; Polanco, Patricio M MD, FACS; Wang, Sam C MD, FACS. Artificial Intelligence Simplification of English and Spanish Surgical Consent Forms: 1-Size Does Not Fit All. Journal of the American College of Surgeons 243(1):p 202-214, July 2026. | DOI: 10.1097/XCS.0000000000001890   Learn more about the Journal of the American College of Surgeons, a monthly peer-reviewed journal publishing original contributions on all aspects of surgery, including scientific articles, collective reviews, experimental investigations, and more.   #JACSOperativeWord

In this episode of The Birth Lounge Podcast, HeHe sits down with pelvic floor physical therapist Hayley Kava, founder of UMA Pelvic Health, to tackle one of the most common pregnancy complaints that doesn't get nearly enough attention: SI joint pain. If you've been told pregnancy pain is "just part of it," this conversation is your reminder that you don't have to simply suffer through it. Hayley explains what's actually happening in your pelvis during pregnancy, why SI joint pain develops, and how your pelvic floor, core, ribcage, breathing, and overall movement patterns all work together. Together, HeHe and Hayley break down why treating the pelvis in isolation often misses the bigger picture, how pregnancy hormones and your changing biomechanics influence pain, and why small changes to the way you move, stand, breathe, and rest can make a huge difference. They also discuss practical tools like SI belts, belly support bands, Pilates balls, yoga blocks, and gentle movement strategies, along with when those tools can help... and when they might not. Hayley also shares why pelvic floor physical therapy isn't just about internal exams (and yes, those are always optional), how to build a supportive birth team, and why individualized care is one of the best investments you can make during pregnancy. Whether you're already dealing with pelvic pain or hoping to prevent it, this episode is packed with practical, evidence-based strategies to help you move more comfortably, feel more supported, and better understand your changing body throughout pregnancy. 00:00 Stop Blaming Pelvic Floor 01:03 Pelvic Floor Basics 01:56 Meet Hayley Kava 03:19 Why SI Pain Matters 06:43 SI Joint Anatomy 09:18 Normal Asymmetry Patterns 12:20 Pubic Pain and Rolling 15:52 Inhibit Then Retrain 17:56 Rubiks Cube Body Model 20:10 Stop Bracing to Sneeze 21:34 Pregnancy Posture Fixes 25:31 Preparing for Labor Moves 29:14 Build Your Care Team 33:39 Pregnancy Compensation Patterns 34:36 Spotting Habitual Postures 36:46 Mindful Pain Check Ins 38:29 Shifting Stance And Sitting 41:29 Tension Beyond Pelvic Floor 43:23 Guarding And SI Joint Myths 46:16 Ribs Hip And Big Picture 47:57 Internal Exam Is Optional 50:38 Daily Tools And Movement 56:43 Services Access And Wrap Up   Guest Bio: Hayley became a pelvic floor therapist in 2017 after a birth injury opened her eyes to the limitations in traditional pelvic rehab. Hayley took her Postural Restoration and Sports Medicine background and dug deep into the literature. Over the years developing an integrative whole person method to treat the pelvic floor. She has become passionate about sharing this method with not only her clients and staff but to the masses via social media, online classes and various trainings for clinicians looking to take a different approach to pelvic rehab. You can learn more about those offerings at hayleykavapt.com   SOCIAL MEDIA: Connect with HeHe on Instagram: https://www.instagram.com/tranquilitybyhehe/  Connect with Hayley on IG: https://www.instagram.com/hayleykavapt/ BIRTH EDUCATION: Learn how to stay in control of your birth and reduce the risk of unnecessary interventions in our Avoid a C-Section Webinar. HeHe breaks down the cascade of interventions, explains what's really happening in the hospital, and shares practical strategies to protect your birth plan, advocate for yourself, and navigate labor with confidence. Perfect for anyone who wants a positive, informed hospital birth experience: https://www.thebirthlounge.com/csection Feeling nervous about speaking up in labor? Our Scripts for Advocacy give you the exact words to handle the most common conversations that can make or break your birth experience. From declining unnecessary interventions to asking the right questions about procedures, these scripts empower you to stay in control, speak confidently, and protect your birth plan — even when the pressure is on. Think of it as your personal toolkit for advocating like a pro, so you can focus on your baby, not the stress: https://www.thebirthlounge.com/Scripts-for-Advocacy And if you haven't grabbed it yet… Snag my free Pitocin Guide to understand the risks, benefits, and red flags your provider may not be telling you about, so you can make informed, powerful decisions in labor: https://www.thebirthlounge.com/pitocin Join The Birth Lounge for judgment-free, evidence-based childbirth education from HeHe that shows you exactly how to navigate hospital policies, avoid unnecessary interventions, and have a trauma-free labor experience, all while feeling wildly supported every step of the way: https://www.thebirthlounge.com/ Want prep delivered straight to your phone? Download The Birth Lounge App for bite-sized birth and postpartum tools you can use anytime, anywhere: https://www.thebirthlounge.com/app   LINKS AND RESEARCH MENTIONED: www.umapelvichealth.com www.hayleykavapt.com Kiapour A, Joukar A, Elgafy H, Erbulut DU, Agarwal AK, Goel VK. Biomechanics of the Sacroiliac Joint: Anatomy, Function, Biomechanics, Sexual Dimorphism, and Causes of Pain. Int J Spine Surg. 2020 Feb 10;14(Suppl 1):3-13. doi: 10.14444/6077. PMID: 32123652; PMCID: PMC7041664. Joukar, Amin MS∗; Shah, Anoli MS∗; Kiapour, Ali PhD∗; Vosoughi, Ardalan Seyed MS∗; Duhon, Bradley MD†; Agarwal, Anand K. MD∗; Elgafy, Hossein MD∗; Ebraheim, Nabil MD∗; Goel, Vijay K. PhD∗. Sex Specific Sacroiliac Joint Biomechanics During Standing Upright: A Finite Element Study. SPINE 43(18):p E1053-E1060, September 15, 2018. | DOI: 10.1097/BRS.0000000000002623

How should nosodes be used within the principles of homeopathy? Denise and Alastair examine the original use of bowel nosodes, Paterson's warning about repetition, and the difference between individualized prescribing and routine protocols.They also explore homeoprophylaxis, epidemic prescribing, and whether fixed nosode schedules remain consistent with a dynamic, individualized system of medicine.Mentioned in this episode:Paterson, John. "The Bowel Nosodes." British Homoeopathic Journal 40, no. 3 (July 1950): 153–162.DOI: 10.1016/S0007-0785(50)80005-4. Presented to the Rhodanienne Homoeopathic Society at the meeting of the International Homoeopathic League Council, Lyons, August 1949.Strange Rare Peculiar is a weekly podcast with Denise Straiges and Alastair Gray of the Institute for the Advancement of Homeopathy and the Academy of Homeopathy Education.This season, we're focusing on truth — what it means to Aude Sapere (“dare to know”) in homeopathy today. From Hahnemann's original insights to the realities of modern practice, research, and education, Denise and Alastair bring over 50 years of experience to conversations that challenge assumptions and invite curiosity.

BUFFALO, NY – July 22, 2026 – A new #PrecisionOncology paper was #Published in Volume 17 of Oncotarget on July 21, 2026, titled “WIN-MTB-2024017 – WIN International Molecular Tumor Board: A 48-year-old female with multiple primary cancers.” The study was led by Oncotarget Editor-in-Chief, Dr. Wafik S. El-Deiry, from the Worldwide Innovative Network (WIN) Association – WIN Consortium and Legorreta Cancer Center at Brown University. Patients who develop multiple primary cancers face unique diagnostic and treatment challenges because each tumor may have distinct biological characteristics requiring different therapeutic approaches. Advances in genomic profiling and precision oncology now enable clinicians to better distinguish between independent tumors and recurrent disease while identifying molecular alterations that may guide individualized treatment strategies. This case report demonstrates how an international molecular tumor board integrated comprehensive genomic data with multidisciplinary expertise to develop personalized recommendations for a patient with an exceptionally complex cancer history. The case describes the clinical journey of a 48-year-old woman carrying a germline BRCA1 mutation who developed multiple primary cancers over nearly two decades, including breast cancer, basal cell carcinoma of the skin, high-grade serous ovarian carcinoma, colon cancer, and small bowel adenocarcinoma. During this time, she underwent multiple surgeries, chemotherapy regimens, targeted therapy with the PARP inhibitor niraparib, and extensive molecular testing to characterize each malignancy. Full press release - https://www.oncotarget.com/news/pr/international-molecular-tumor-board-explores-personalized-treatment-strategies-for-a-patient-with-multiple-primary-cancers/ DOI - https://doi.org/10.18632/oncotarget.28899 Correspondence to - Wafik S. El-Deiry - wafik_el-deiry@brown.edu Abstract video - https://www.youtube.com/watch?v=4KIDbmq6ui8 Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28899 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, precision oncology, molecular tumor board To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

Episode Summary Erin and Rachel return to the Hundred Acre Wood for Winnie the Pooh (2011), the sequel to The Many Adventures of Winnie the Pooh (1977). Although it's stuffed with as much fluff as its protagonist, nostalgia and a 69-minute run time make this benign film pleasantly watchable.  Episode Bibliography Anderson, J. [@jenna.sais.quoi.paris]. (n.d.). Reels [Instagram profile]. Instagram. Retrieved July 5, 2026 from https://www.instagram.com/jenna.sais.quoi.paris Anderson, S. & Hall, D. (Directors). (2011). Winnie the Pooh [Film]. Walt Disney Animation Studios. Armstrong, J. (2011, July 25). Winnie The Pooh's Directors Stephen Anderson and Don Hall: Back to the Hundred Acre Wood – Animated Views. Animated Views. https://animatedviews.com/2011/winnie-the-pooh%E2%80%99s-directors-stephen-anderson-and-don-hall-back-to-the-hundred-acre-wood/ Chang, J. (2011, April 1). Winnie the Pooh. Variety. https://variety.com/2011/film/reviews/winnie-the-pooh-1117944948/ Chen, T. (2016, September 16). People On Tumblr Are Obsessed With This Guy Who Gets Coffee On Movie Sets. BuzzFeed News. https://www.buzzfeednews.com/article/tanyachen/people-on-tumblr-are-obsessed-with-carlos-the-coffee-guy Culture Editor. (2011, April 18). Review: Winnie the Pooh. Platform. https://web.archive.org/web/20161229101056/http://platform-online.net/2011/04/review-winnie-the-pooh/ Denham, J. (2016, September 19). The guy that makes Disney animators coffee has been getting 'caffeination' credits for years. The Independent. https://www.the-independent.com/arts-entertainment/films/news/the-guy-that-makes-disney-animators-coffess-has-been-getting-caffeination-credits-for-years-a7316541.html Desowitz, B. (2011, July 15). Reinventing 'Winnie the Pooh'. Animation World Network. https://www.awn.com/animationworld/reinventing-winnie-pooh Don Hall (filmmaker). (n.d.). Wikipedia. https://en.wikipedia.org/wiki/Don_Hall_(filmmaker) Ebert, R. (2011, July 13). “Nobody can be uncheered with a balloon”. RogerEbert.com. https://www.rogerebert.com/reviews/winnie-the-pooh-2011 Goldstein, G. (2011, July 15). Movie Review: ‘Winnie the Pooh'. Los Angeles Times. https://www.latimes.com/entertainment/la-xpm-2011-jul-15-la-et-winnie-the-pooh-20110715-story.html Hill, J. (2010, June 3). GeneralDisney's going Back to the Future with Winnie the Pooh. Jim Hill Media. https://limegreen-loris-912771.hostingersite.com/disneys-going-back-to-the-future-with-winnie-the-pooh/ King, S. (2011, July 13). New ‘Winnie the Pooh' movie goes back to its Hundred Acre Wood roots. Los Angeles Times. https://www.latimes.com/entertainment/la-xpm-2011-jul-13-la-et-winnie-the-pooh-20110713-story.html Milne, A.A. (1926). Winnie-the-Pooh (E.H. Shepard, Illus.). Methuen.  Milne, A.A. (1928). The House at Pooh Corner. (E.H. Shepard, Illus.). Methuen. Ness, M. (2016, December 1). Hunting for Honey in the Franchise: Disney's Winnie the Pooh (2011). Reactor. https://reactormag.com/hunting-for-honey-in-the-franchise-disneys-winnie-the-pooh-2011/ Nimri, N. (n.d.) Self care is collective care is community care. Slow Factory. https://slowfactory.earth/readings/self-care-is-collective-care-is-community-care/ Radish, C. (2011, July 7). Don Hall and Stephen Anderson Interview WINNIE THE POOH. Collider. https://collider.com/don-hall-stepen-anderson-interview-winnie-the-pooh/ Rudulph, H. W. (2015, April 27). Get That Life: How I Co-Wrote the Music and Lyrics for "Frozen". Cosmopolitan. https://www.cosmopolitan.com/career/interviews/a39513/get-that-life-kristen-anderson-lopez/ Scott, A. O. (2011, July 14). 'Winnie the Pooh,' From Disney - Review - The New York Times. New York Times. https://www.nytimes.com/2011/07/15/movies/winnie-the-pooh-from-disney-review.html Soteriou, H. (2011, April 18). Winnie the Pooh returns to animate cinemas. BBC News. https://www.bbc.com/news/entertainment-arts-13066105 Stephen Anderson (artist). (n.d.). Wikipedia. https://en.wikipedia.org/wiki/Stephen_Anderson_(artist) Watts, T.W., Duncan, G.J., & Quan, H. (2018). Revisiting the Marshmallow Test: A conceptual replication investigating links between early delay of gratification and later outcomes. Psychological science, 29(7), 1159-1177. Doi: 10.1177/0956797618761661 Winnie the Pooh (2011). (n.d.). Box Office Mojo. https://www.boxofficemojo.com/title/tt1449283/ Winnie the Pooh (2011). (n.d.). IMDb. https://www.imdb.com/title/tt1449283/?ref_=nv_sr_srsg_3_tt_8_nm_0_in_0_q_winnie%20the%20pooh Winnie the Pooh (2011 film). (n.d.). Wikipedia. https://en.wikipedia.org/wiki/Winnie_the_Pooh_(2011_film) Winnie the Pooh (soundtrack). (n.d.). Wikipedia. https://en.wikipedia.org/wiki/Winnie_the_Pooh_(soundtrack) Zahed, R. (2011, July 10). Back to the Days of Christopher Robin & Pooh. Animation Magazine. https://www.animationmagazine.net/2011/07/back-to-the-days-of-christopher-robin-pooh/ Zooey Deschanel Performs Three Songs for Winnie the Pooh. (2011, March 31). ComingSoon.net. https://web.archive.org/web/20110826070731/http://www.comingsoon.net/news/movienews.php?id=75804

Wir springen in dieser Folge in die USA, genauer nach San José in Kalifornien. Dort steht ein auf den ersten Blick rätselhaftes Gebäude, bekannt als das Winchester Mystery House. Es ist heute eine viel besuchte Attraktion, der eine geisterhafte Legende zugrunde liegt. Wir sprechen in dieser Folge über diese Legende: wie dieses Haus zustande kam, wer die angeblich so geheimnisvolle Bauherrin war und warum gerade das Ende des 19. Jahrhunderts in den USA ein so fruchtbarer Boden für Geistergeschichten ist. // Erwähnte Folgen - GAG237: Friedrich Anton Mesmer und der Animalische Magnetismus – https://gadg.fm/237 - GAG505: William H. Mumler, Geisterfotograf – https://gadg.fm/505 - GAG546: Sarah Biffin, Miniaturmalerin – https://gadg.fm/546 // Literatur - Haag, Pamela, The Gunning of America: Business and the Making of American Gun Culture, New York: Basic Books, 2016. - Ignoffo, Mary Jo, Captive of the Labyrinth: Sarah L. Winchester, Heiress to the Rifle Fortune, Columbia: University of Missouri Press, 2010. - Junker, Christine R., „Unruly Women and Their Crazy Houses: Sarah Winchester's Unconventional Domesticity“, in: Home Cultures 12/3 (2015), S. 329–346, DOI: 10.1080/17406315.2015.1084763. - Lueck, Amy J., „Haunting Women's Public Memory: Ethos, Space, and Gender in the Winchester Mystery House“, in: Rhetoric Review 40/2 (2021), S. 107–122, DOI: 10.1080/07350198.2021.1883832. Das eingangs erwähnte Past Puzzle findet sich hier: https://www.pastpuzzle.de Hier gibt's die von Lene erwähnte "Lore"-Folge: https://www.lorepodcast.com/episodes/79 //Aus unserer Werbung Du möchtest mehr über unsere Werbepartner erfahren? Hier findest du alle Infos & Rabatte: https://linktr.ee/GeschichtenausderGeschichte //Geschichten aus der Geschichte jetzt auch als Brettspiel! Werkelt mit uns am Flickerlteppich! Gibt es dort, wo es auch Becher, T-Shirts oder Hoodies zu kaufen gibt: https://geschichte.shop // Wir sind jetzt auch bei CampfireFM! Wer direkt in Folgen kommentieren will, Zusatzmaterial und Blicke hinter die Kulissen sehen will: einfach die App installieren und unserer Community beitreten: https://www.joincampfire.fm/podcasts/22 //Wir haben auch ein Buch geschrieben: Wer es erwerben will, es ist überall im Handel, aber auch direkt über den Verlag zu erwerben: https://www.piper.de/buecher/geschichten-aus-der-geschichte-isbn-978-3-492-06363-0 Wer unsere Folgen lieber ohne Werbung anhören will, kann das über eine kleine Unterstützung auf Steady oder ein Abo des GeschichteFM-Plus Kanals auf Apple Podcasts tun. Wir freuen uns, wenn ihr den Podcast bei Apple Podcasts oder wo auch immer dies möglich ist rezensiert oder bewertet. Wir freuen uns auch immer, wenn ihr euren Freundinnen und Freunden, Kolleginnen und Kollegen oder sogar Nachbarinnen und Nachbarn von uns erzählt! Du möchtest Werbung in diesem Podcast schalten? Dann erfahre hier mehr über die Werbemöglichkeiten bei Seven.One Audio: https://www.seven.one/portfolio/sevenone-audio

When colleges and universities think about student well-being, the conversation often begins and ends with counseling centers. But what if student well-being is much broader than mental health services alone? In this episode of On Campus, Dr. Maithreyi Gopalan, Associate Professor at the University of Oregon, for a discussion about how institutions can build a campus-wide approach to student well-being by focusing on belonging, connection, and student flourishing. Based on her research, Dr. Gopalan explains why a student's sense of belonging is strongly connected to persistence, graduation, academic success, and mental health outcomes. The conversation explores practical strategies for higher education leaders, including measuring belonging as an institutional outcome, conducting regular student pulse checks, strengthening advising and first-year experiences, and creating meaningful connections throughout the student journey. Dr. Gopalan also discusses the role faculty play as "first responders" in supporting students, the importance of equity-centered well-being initiatives, and why institutions must move beyond reactive approaches to create environments where all students can thrive. Whether you're a student affairs professional, faculty member, administrator, or higher education leader, this episode offers research-based insights for building a more supportive and successful campus community.  Resources Gopalan, M., & Brady, S. T. (2020). College Students' Sense of Belonging: A National Perspective. Educational Researcher, 49(2), 134 137. https://protect.checkpoint.com/v2/r01/___https://doi.org/10.3102/0013189X19897622___.YzJ1OmNpdGlwcm9ncmFtMTpjOm86NjgwOGY4OTBmZjYyNzJkNjA4YjdkM2YwMDYwMTgyODY6NzowMzMxOjYxYmQ2ZGQxMTU1N2ExYzI5YmVmYTQ0MmYyNGMxNmE4M2YzMmMzZjUwMmU4YWZjOWRiNWFjYWJjMmU5MDQ3NjQ6dDpUOkY Gopalan, M., Linden-Carmichael, A. Lanza, S. (2022). College Students' Sense of Belonging and Mental Health Amidst the COVID-19 Pandemic, Journal of Adolescent Health, 70(2), 228-233. https://protect.checkpoint.com/v2/r01/___https://doi.org/10.1016/j.jadohealth.2021.10.010___.YzJ1OmNpdGlwcm9ncmFtMTpjOm86NjgwOGY4OTBmZjYyNzJkNjA4YjdkM2YwMDYwMTgyODY6NzpjOTJiOjRmN2IxNTc1Mjc3MWIxYmYxZjA5MDIzNDIyZDcwN2FiY2E2ZmExYzgwZmMxNjdhZGQ2MmE1ZTFlMWZlYWY1OWY6dDpUOkY Murphy, M.C., Gopalan, M., Carter, E. R., Emerson, K. T. U., Bottoms, B. L., and Walton, G.M., (2020). A customized belonging intervention improves retention of socially disadvantaged students at a broad-access university Science Advances, 6(29). DOI: 10.1126/sciadv.aba4677 Walton, & Cohen. (2007). A question of belonging: Race, social fit, and achievement. Journal of Personality and Social Psychology, 92(1), 82. https://protect.checkpoint.com/v2/r01/___https://doi.org/10.1037/0022-3514.92.1.82___.YzJ1OmNpdGlwcm9ncmFtMTpjOm86NjgwOGY4OTBmZjYyNzJkNjA4YjdkM2YwMDYwMTgyODY6NzpiZmI3OmM5YmYwYTY2YmE3ZGQxMzY0MzM1ZTg2OWIwYjBkNTZmYzNmMGEyNzhkMmQ5ZThiZGEzZTc2M2ZiZTY0NDkzMjA6dDpUOkY 

All of this week's episodes of It Could Happen Here put together in one large file. Palestine in the World Cup What's Wrong with Human Rights What's Wrong with Human Rights, Pt. 2 A Report from the Great American State Fair Executive Disorder: Platner Allegations, Return of the Tariffs, ICE Shootings You can now listen to all Cool Zone Media shows, 100% ad-free through the Cooler Zone Media subscription, available exclusively on Apple Podcasts. So, open your Apple Podcasts app, search for “Cooler Zone Media” and subscribe today! http://apple.co/coolerzone Sources/Links: Palestine in the World Cup https://jewishcurrents.org/de-normalizing-israeli-normalization-at-the-world-cup https://agsi.org/analysis/palestine-activism-in-the-world-cup/ https://www.aljazeera.com/video/newsfeed/2026/6/12/activists-form-human-palestine-flag-at-world-cup-opener-in-mexico-city https://www.nbcnewyork.com/world-cup/palestinian-head-soccer-says-denied-us-visa-attend-world-cup/6512472/ https://www.middleeasteye.net/trending/bosnia-advances-world-cup-free-palestine-chants-fans-go-viral-once-again https://www.aljazeera.com/features/2026/6/22/football-war-and-solidarity-why-gaza-fans-turned-to-spain-this-world-cup https://www.aljazeera.com/sports/2026/6/12/palestine-football-chief-says-he-wasnt-granted-us-visa-to-attend-world-cup What's Wrong with Human Rights Human Rights as Moral Progress? A Critique by Jarett ZigonCULTURAL ANTHROPOLOGY, Vol. 28, Issue 4, pp. 716–736. ISSN 0886-7356, online ISSN 1548-1360. C 2013 by the American Anthropological Association. All rights reserved. DOI: 10.1111/cuan.12034 Agamben, Arendt and Human Rights: Bearing Witness to the Human. 2012John Lechte & Saul NewmanState of Exception. 2005Giorgio Agamben, translated by Kevin Attell The Need for Roots: Prelude to a Declaration of Duties Towards Mankind Simone Weil. Routledge Classics 2002 Philosophize This! - Episode #191: The Modern Day Concentration Camp and the Failure of Human Rights by Stephen West Executive Disorder: Platner’s Allegations, Return of the Tariffs, ICE Shootings https://www.aljazeera.com/news/liveblog/2026/7/3/iran-war-live-tehran-slams-us-ahead-of-huge-funeral-for-ali-khamenei?update=4731595 https://thehill.com/homenews/senate/5955865-mitch-mcconnell-senate-health-status/ https://www.cnn.com/2026/07/06/us/graham-platner-racicot-allegation-maine-invs https://www.politico.com/news/2026/07/06/graham-platner-sexual-assault-allegation-00987737 https://x.com/akela_lacy/status/2074604814810415293?s=20 https://x.com/grace_panetta/status/2074266651244073227?s=20 https://www.nytimes.com/2026/07/06/us/politics/who-would-replace-graham-platner-maine.html https://x.com/sahilkapur/status/2074678417006420067 https://www.bangordailynews.com/2026/07/08/politics/elections/maine-democrats-want-convention-replace-graham-platner/ https://ustr.gov/about/policy-offices/press-office/press-releases/2026/june/ustr-makes-findings-and-proposes-action-60-section-301-investigations-relating-failures-take-action https://thediplomat.com/2026/06/asean-and-trumps-section-301-tariffs/ https://www.reuters.com/business/latin-american-countries-some-steelmakers-argue-us-tariff-exemptions-2026-07-07/ https://www.congress.gov/crs_external_products/IF/PDF/IF11346/IF11346.31.pdf https://www.yahoo.com/news/politics/articles/democratic-attorneys-general-oppose-latest-172500930.html https://www.msn.com/en-in/news/other/fresh-trump-tariff-threat-looms-what-is-india-s-strong-stand-on-us-section-301-probe-that-proposes-12-5-duties-explained/ar-AA27rLMq https://www.msn.com/en-ca/money/general/canada-says-there-s-no-basis-for-trump-s-forced-labour-tariffs/ar-AA27sMJy https://www.reuters.com/world/french-lawmakers-back-police-shootings-law-dubbed-licence-kill-by-critics-2026-07-08/ https://www.citizen.org/wp-content/uploads/Complaint-in-IALDF-v.-Rubio.pdf https://www.cnn.com/2026/07/07/us/houston-ice-shooting-death https://www.reuters.com/world/americas/fatal-ice-shooting-houston-sparks-demands-transparency-independent-investigation-2026-07-08/ https://www.nytimes.com/2026/07/08/us/houston-ice-shooting.html https://www.wgal.com/article/pa-harrisburg-ice-agent-shoots-video/71807714 https://www.cnn.com/2026/07/04/us/live-news/july-4-trump-speech-america-250?post-id=cmr792ght00053b6r6tl4lvzn https://www.cnn.com/2026/07/04/us/live-news/july-4-trump-speech-america-250?post-id=cmr78t2tf000e3b6rxm0jppbj https://www.npr.org/2026/07/04/g-s1-132025/mount-rushmore-speech-trump-july-4-250See omnystudio.com/listener for privacy information.

In this Supplement Stack Series episode, Nurse Doza breaks down his Good Poops Protocol—a simple liver and gut detox built on three MSW supplements: the Gut glutamine powder, Liver Boost, and Berberine. He explains why gut issues often show up before liver and gallbladder trouble, how repairing the digestive tract may ease inflammation, and how pairing the two-month reset with a Mediterranean diet and better daily habits supports better energy, weight, and, of course, better poops. FEATURED PARTNER The Good Poops Protocol bundles three MSW Nutrition supplements—the Gut glutamine powder, Liver Boost, and Berberine—into one two-month liver and gut detox designed to help reset, repair, and support the digestive tract discussed in this episode. Because gut, liver, and gallbladder issues so often travel together, the protocol targets all three at once, and pairs best with a Mediterranean-style diet and simple daily habits.

This week we delve again into the world of adult congenital heart disease and specifically the realm of biomarkers when we review a recent report of the proteomics of the adult Fontan patient. What is proteomics and how can this inform our understanding of the pathophysiology and adaptive pathways of the Fontan circulation? Are there meaningful differences in the patterns of protein expression between the adult Fontan patient and control 2 ventricle subjects? What might account for differences and how can we understand these differences to explain outcomes in the Fontan adult patient? We speak with the first and senior authors of this week's work, Professor Alexander Opotowsky of the University of Cincinnati and Mr. Ismael Assi who is a Sarnoff Fellow and soon to be 4th year medical student at the University of Cincinnati. DOI: 10.1016/j.jacadv.2026.102810 

We are a decade into the CAR-T era, and what to long term outcomes look like with tisagenlecleucel in B-cell lymphomas? Orca-T is approved, an allogenic cocktail of stem & progenitor cells, Tregs, and then conventional T-cells. Neato. Polar-Go! or PolARGo? And the concept of T-cell "stemless" is intriguing with possibilities: DOI: 10.1056/NEJMcibr2601002 Learning Oncology Companion:https://www.kelleycpharmd.com/learning-oncology-companion-oncopharm

As colorectal cancer rates rise among younger adults, surgeons are increasingly caring for patients with rectal cancer who are pregnant or hoping to preserve future fertility. With more individuals delaying childbearing, balancing effective cancer treatment with fertility preservation and maternal–fetal safety has become an important clinical challenge. This timely topic was recently highlighted by Dr. Sharon Suwanabol during a presentation at the American Society of Colon and Rectal Surgeons annual meeting 2026. In this episode, we explore the intersection of rectal cancer, fertility, and pregnancy through a multidisciplinary, case-based discussion. We review how surgery, chemotherapy, and pelvic radiation can affect fertility and sexual function in both men and women, and why early counseling and referral to reproductive endocrinology specialists are essential. The discussion also emphasizes that evaluation and treatment during pregnancy can often be performed safely, with care individualized based on tumor stage, gestational age, and the patient's goals and values. Hosts and discussants ·      Dr. Betelhem Yohannes, General surgery resident at the University of Washington ·      Dr. Griffen Allen, General surgery resident at the University of Washington  ·      Dr. Raga Siddharthan, Assistant Professor of Surgery in the Section of Colorectal Surgery at the University of Washington  ·      Dr. Stacey Cohen, Professor in the Division of Hematology and Oncology at the University of Washington and a gastrointestinal medical oncologist at Fred Hutch Cancer Center, specializing in colorectal and other GI cancers. Learning objectives ·      Describe the impact of rectal cancer surgery on fertility, sexual function, and future childbearing potential. ·      Review the effects of chemotherapy and pelvic radiation on reproductive health and fertility preservation. ·      Discuss available fertility preservation strategies and the importance of early pre-treatment counseling and referral. ·      Recognize the diagnostic challenges of rectal cancer during pregnancy, including overlapping gastrointestinal symptoms. ·      Review appropriate staging and workup considerations for suspected rectal cancer in pregnant patients. ·      Discuss multidisciplinary management strategies for rectal cancer during pregnancy, including individualized treatment sequencing. ·      Examine ethical and patient-centered considerations when balancing maternal cancer treatment and fetal outcomes. References  Siegel RL, Wagle NS, Star J, Kratzer TB, Smith RA, Jemal A. Colorectal cancer statistics, 2026. CA Cancer J Clin. 2026;76(2):e70067. doi:10.3322/caac.70067 [https://pubmed.ncbi.nlm.nih.gov/38240409/] Pregnancy at Age 35 Years or Older: ACOG Obstetric Care Consensus No. 11. Obstet Gynecol. 2022;140(2):348-366. doi:10.1097/AOG.0000000000004873 [https://pubmed.ncbi.nlm.nih.gov/35640237/] Stal J, YI SY, Cohen-Cutler S, et al. Fertility Preservation Discussions Between Young Adult Rectal Cancer Survivors and Their Providers: Sex-Specific Prevalence and Correlates. Oncologist. 2022;27(7):579-586. doi:10.1093/oncolo/oyac052 [https://pubmed.ncbi.nlm.nih.gov/35708892/] Druvefors E, Myrelid P, Andersson RE, Landerholm K. Female and Male Fertility after Colectomy and Reconstructive Surgery in Inflammatory Bowel Disease: A National Cohort Study from Sweden. J Crohns Colitis. 2023;17(10):1631-1638. doi:10.1093/ecco-jcc/jjad079 [https://pubmed.ncbi.nlm.nih.gov/37341355/] Ito M, Tsukada Y, Watanabe J, et al. Long-term survival and functional outcomes of laparoscopic surgery for clinical stage I ultra-low rectal cancers located within 5 cm of the anal verge: A prospective phase II trial (Ultimate trial). Ann Surg. Published online April 1, 2024. doi:10.1097/SLA.0000000000006290 [https://pubmed.ncbi.nlm.nih.gov/38629555/] Teh WT, Stern C, Chander S, Hickey M. The impact of uterine radiation on subsequent fertility and pregnancy outcomes. Biomed Res Int. 2014;2014:482968.  Johnson GGRJ, Park J, Helewa RM, Goldenberg BA, Nashed M, Hyun E. Total neoadjuvant therapy for rectal cancer: a guide for surgeons. Can J Surg. 2023 Apr 21;66(2):E196-E201. doi: 10.1503/cjs.005822. PMID: 37085291; PMCID: PMC10125160. [https://pubmed.ncbi.nlm.nih.gov/37085291/] Naren G, Guo J, Bai Q, Fan N, Nashun B. Reproductive and developmental toxicities of 5-fluorouracil in model organisms and humans. Expert Rev Mol Med. 2022 Jan 31;24:e9. doi: 10.1017/erm.2022.3. PMID: 35098910; PMCID: PMC9884763. [https://pubmed.ncbi.nlm.nih.gov/35098910/] National Comprehensive Cancer Network. (2026). NCCN Clinical Practice Guidelines in Oncology: Rectal Cancer (Version 2.2026). Retrieved from NCCN Guidelines for Rectal Cancer [https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1449] Oktay, Kutluk M.D., Ph.D.. Expert Commentary on Fertility Preservation in Colorectal Cancers: Current State and Practical Tips for the Cancer Practitioner. Diseases of the Colon & Rectum 63(6):p 726-727, June 2020. | DOI: 10.1097/DCR.0000000000001688 [https://pubmed.ncbi.nlm.nih.gov/32479532/] Stal J, YI SY, Cohen-Cutler S, et al. Fertility Preservation Discussions Between Young Adult Rectal Cancer Survivors and Their Providers: Sex-Specific Prevalence and Correlates. Oncologist. 2022;27(7):579-586. doi:10.1093/oncolo/oyac052 [https://pubmed.ncbi.nlm.nih.gov/35708892/] Gentile G, Ciccarone M. Management of fertility preservation in young female patients with gastrointestinal cancer: A case series and systematic literature review. Curr Probl Cancer. 2025;57:101221. doi:10.1016/j.currproblcancer.2025.101221 [https://pubmed.ncbi.nlm.nih.gov/39598263/] Saif MW. Management of colorectal cancer in pregnancy: a multimodality approach. Clin Colorectal Cancer. 2005;5(4):247-256. doi:10.3816/ccc.2005.n.035 [https://pubmed.ncbi.nlm.nih.gov/16183863/] Rogers JE, Dasari A, Eng C. The Treatment of Colorectal Cancer During Pregnancy: Cytotoxic Chemotherapy and Targeted Therapy Challenges. Oncologist. 2016 May;21(5):563-70. doi: 10.1634/theoncologist.2015-0362. Epub 2016 Mar 21. PMID: 27000464; PMCID: PMC4861360. [https://pubmed.ncbi.nlm.nih.gov/27000464/] Jiang Q, Hua H. Fertility in young-onset colorectal patients with cancer: a review. Oncologist. 2024;29(10):e1237-e1245. doi:10.1093/oncolo/oyae141 [https://pubmed.ncbi.nlm.nih.gov/39292850/] Dolmans MM, Hollanders de Ouderaen S, Demylle D, Pirard C. Utilization rates and results of long-term embryo cryopreservation before gonadotoxic treatment. J Assist Reprod Genet. 2015;32(8):1233-1237. doi:10.1007/s10815-015-0533-z [https://pubmed.ncbi.nlm.nih.gov/26162569/ Moawad NS, Santamaria E, Rhoton-Vlasak A, Lightsey JL. Laparoscopic Ovarian Transposition Before Pelvic Cancer Treatment: Ovarian Function and Fertility Preservation. J Minim Invasive Gynecol. 2017;24(1):28-35. doi:10.1016/j.jmig.2016.08.831 [https://pubmed.ncbi.nlm.nih.gov/27599763/] Fish R. Ovarian transposition in rectal cancer: uncertain benefit at a high price. Colorectal Dis. 2022;24(6):706-707. doi:10.1111/codi.16086 [https://pubmed.ncbi.nlm.nih.gov/35191146/] Ribeiro R, Baiocchi G, Moretti-Marques R, Linhares JC, Costa CN, Pareja R. Uterine transposition for fertility and ovarian function preservation after radiotherapy. Int J Gynecol Cancer. 2023;33(12):1837-1842. Published 2023 Dec 4. doi:10.1136/ijgc-2023-004723 [https://pubmed.ncbi.nlm.nih.gov/38104863/] Haggar F, Pereira G, Preen D, et al. Maternal and neonatal outcomes in pregnancies following colorectal cancer. Surg Endosc. 2013;27(7):2327-2336. doi:10.1007/s00464-012-2774-6 [https://pubmed.ncbi.nlm.nih.gov/23645367/] Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more.  If you liked this episode, check out our recent episodes here: https://behindtheknife.org/listenBehind the Knife Premium: https://behindtheknife.org/premiumOral Board Review: https://behindtheknife.org/oral-boardOral Board Simulator: https://behindtheknife.org/oral-board/simulatorGeneral Surgery Oral Board Review Course: https://behindtheknife.org/premium/general-surgery-oral-board-reviewTrauma Surgery Video Atlas: https://behindtheknife.org/premium/trauma-surgery-video-atlasDominate Surgery: A High-Yield Guide to Your Surgery Clerkship: https://behindtheknife.org/premium/dominate-surgery-a-high-yield-guide-to-your-surgery-clerkshipDominate Surgery for APPs: A High-Yield Guide to Your Surgery Rotation: https://behindtheknife.org/premium/dominate-surgery-for-apps-a-high-yield-guide-to-your-surgery-rotationVascular Surgery Oral Board Review Course: https://behindtheknife.org/premium/vascular-surgery-oral-board-reviewColorectal Surgery Oral Board Review Course: https://behindtheknife.org/premium/colorectal-surgery-oral-board-reviewSurgical Oncology Oral Board Review Course: https://behindtheknife.org/premium/surgical-oncology-oral-board-reviewCardiothoracic Oral Board Review Course: https://behindtheknife.org/premium/cardiothoracic-surgery-oral-board-reviewDownload our App:Apple App Store: https://apps.apple.com/us/app/behind-the-knife/id1672420049Android/Google Play: https://play.google.com/store/apps/details?id=com.btk.app&hl=en_US