Podcasts about advances

Have you ever lived in a mindset where you're basically waiting for the other shoe to drop, hope feels impossible or too dangerous? It can feel safer to fly low, embrace pessimism and cynicism and think, “if life turns out half as bad as I imagine, then at least I'll be ready for it.” That's the kind of mindset Stephanie had when she was younger. Stephanie welcomes Nicole Zasowski, author and therapist, who shares wisdom on reclaiming joy and celebration in a world often dominated by worry and pessimism. Nicole's journey and research reveal that joy isn't just an emotional response, but a courageous, spiritual discipline rooted in God's faithfulness. Despite her deep faith, she had concluded that joy and celebration were risky. She was sure that celebration would come with a catch, so she became practiced in praying for the miracle while preparing to mourn and dreaming while rehearsing disaster. And yet she discovered that our methods of self-protection came at a cost. A lot of the loss we experience in our lives is not only the grief and the disappointment itself, but also the joy that we overlook because we are too afraid to embrace it, she tells us. That's the conversation on Gospel Spice today. Understanding the Struggle with Joy Nicole begins by dispelling the myth that celebration and joy come naturally to her—in fact, her books were born from seasons marked by change, loss, and disappointment. Through experiences like moving across the country and enduring infertility and miscarriages, Nicole discovered a heartbreaking truth: much of her loss was not just in what she lacked, but in her refusal to embrace the goodness that God placed in her path out of fear that it would be taken away. This led her into research, both biblical and scientific, to understand why joy can feel so vulnerable and difficult, especially when we've experienced pain. Redefining Celebration: A Spiritual Discipline American and Western cultures, Nicole notes, often see celebration as a reward for good news or accomplishments. However, the Bible—especially the Old Testament—demonstrates celebration as a spiritual rhythm and discipline, not just a reaction. The Israelites practiced regular, scheduled celebrations and feasts, regardless of their current circumstances. These rhythms were not designed to reward themselves for their goodness, but to remember and honor God's consistent faithfulness. Celebration, then, is about choosing remembrance: looking back at God's goodness and letting that fuel hope, courage, and anticipation about the future—even when circumstances are hard. The Vulnerability of Joy Joy is inherently vulnerable because it opens our hearts to the possibility of loss. For those who have experienced pain, pessimism and cynicism can become self-protective mechanisms. However, Nicole's research and experience as a therapist show that numbing ourselves to joy doesn't actually protect us. Rather, it diminishes our ability to savor God's goodness and leaves us empty-handed in difficult times. Practical Tools for Practicing Joy Nicole emphasizes that joy, like any virtue, can and must be intentionally practiced. Two key habits can help rewire our hearts toward joy: 1.      Savoring: Take mental “snapshots” of small moments, deliberately noticing what you see, hear, smell, taste, and feel. This helps your brain store joyful experiences that might otherwise go unnoticed. 2.      Thanksgiving (vs. gratitude): Beyond silently feeling grateful, speak and express thanks out loud—to God or others. Research shows that this actually heightens and solidifies joy inside us. Key Takeaways from our conversation ·         Joy and celebration are not merely emotions; they are spiritual practices and choices that shape us. ·         God invites us into rhythms of celebration even when our feelings or circumstances do not match, because it roots us deeper in remembrance of His faithfulness. ·         Practicing joy often feels counterintuitive—especially in pain—but it is the way God designed us to process life and hope. ·         Tools like savoring and thanksgiving can help transform our hearts and brains to default toward joy instead of worry or cynicism. Nicole encourages us that it's never too late to begin practicing joy, regardless of our life's season. The discipline of joy prepares us for eternity, deepening our delight in God and training our hearts for hope and celebration—no matter what comes our way. MORE ABOUT NICOLE ZASOWSKI Nicole Zasowski is a licensed marriage and family therapist and author of What If It's Wonderful, From Lost to Found and her new Bible Study Daring Joy. She is also the coauthor of Advances and Techniques in Restoration Therapy and Families and Forgiveness. As a writer who wears her heart proudly on her sleeve, Nicole's work is a weave of biblical wisdom, psychological expertise, and vulnerable storytelling. Often praised for her wisdom and approachable style, Nicole is a sough-after speaker, frequently teaching at conferences, retreats, and women's events around the country on topics that integrate faith and psychology. In addition to her private practice, Nicole's therapeutic work has included teaching as an adjunct professor at Alliance Theological Seminary in New York and leading marriage intensives at the Hideaway Experience. Nicole and her husband, Jimmy, are the grateful parents of three young children. Her favorite place to be is looking for sea glass on the Connecticut shoreline, exploring a New England town or New York City neighborhood, or sitting in her front yard around a fire with her family, friends, and neighbors. Meet Nicole at https://www.nicolezasowski.com/  MORE ABOUT “DARING JOY” Joy can feel risky. When you've experienced pain of any kind, it can feel easier not to dream than to be disappointed, or not to hope than to be left heartbroken. If you ever feel like it's safer not to embrace joy at all than to hold something that might break, you're not alone. Thankfully, the Bible paints a different picture—one that gives you the courage to hold on to joy regardless of your circumstances. https://www.nicolezasowski.com/daring-joy  MORE ABOUT “WHAT IF IT'S WONDERFUL” What If It's Wonderful? Author and marriage and family therapist Nicole Zasowski knows that it's difficult to trust joy and find the courage to celebrate when you have endured seasons of disappointment and despair. When God has been your faithful anchor in the storm, does joy then leave you unmoored? Nicole reminds us that we can stay tethered to the hope of Christ in seasons of celebration, because even joyful days hold the learning, growth, and intimate encounters with Jesus that our hearts crave. What If It's Wonderful? offers a new perspective. With a compelling psychological and spiritual case for the importance of embracing joy and celebration, even when it feels scary. https://www.nicolezasowski.com/wonderful  We invite you to check out the first episode of each of our series, and decide which one you will want to start with. Go to gospelspice.com for more, and go especially to gospelspice.com/podcast to enjoy our guests! Interested in our blog? Click here: gospelspice.com/blog Identity in the battle | Ephesians https://www.podcastics.com/episode/74762/link/ Centering on Christ | The Tabernacle experience https://www.podcastics.com/episode/94182/link/ Shades of Red | Against human oppression https://www.podcastics.com/episode/115017/link/ God's glory, our delight  https://www.podcastics.com/episode/126051/link/   Support us on Gospel Spice, PayPal and Venmo!

Send us a textSusan and Alex are joined by co-host Josh Burris and special guest Nicole Zasowski for a heartfelt conversation around the question: "How does God call us to talk with others about pain?" Together, they explore what it looks like to hold space for one another, speak truth with compassion, and reflect God's love in our hardest conversations.NICOLE ZASOWSKI  is a licensed marriage and family therapist and author of What If It's Wonderful, From Lost to Found and her new Bible Study Daring Joy. She is also the coauthor of Advances and Techniques in Restoration Therapy and Families and Forgiveness. As a writer who wears her heart proudly on her sleeve, Nicole's work is a weave of biblical wisdom, psychological expertise, and vulnerable storytelling. Often praised for her wisdom and approachable style, Nicole is a sough-after speaker, frequently teaching at conferences, retreats, and women's events around the country on topics that integrate faith and psychology.In addition to her private practice, Nicole's therapeutic work has included teaching as an adjunct professor at Alliance Theological Seminary in New York and leading marriage intensives at the Hideaway Experience.Nicole and her husband, Jimmy, are the grateful parents of three young children. Her favorite place to be is looking for sea glass on the Connecticut shoreline, exploring a New England town or New York City neighborhood, or sitting in her front yard around a fire with her family, friends, and neighbors.Nicole would love to connect with you on Instagram @nicolezasowski. You can also subscribe to Nicole's newsletter to have wisdom and encouragement sent straight to your inbox!In Nicole's newest Bible study, Daring Joy, you will learn to release fear, comparison, and control so you can embrace the joy God designed you for. You can find all her books and resources here: https://www.nicolezasowski.com/Thanks for listening to the Embodied Holiness Podcast. We invite you to join the community on Facebook and Instagram @embodiedholiness. You can find all our episodes and more at www.embodiedholiness.com. Embodied Holiness is a ministry of Parkway Heights United Methodist Church in Hattiesburg, MS. If you're in the Hattiesburg area and are looking for a church home, we'd love to meet you and welcome you to the family. You can find out more about Parkway Heights at our website.

This week, Ryan and David unpack Bitcoin's explosive run to $111K and the macro chaos driving it—specifically, the U.S. Treasury's failed bond auction and what it signals for the dollar. They break down the Senate's landmark stablecoin bill (and Elizabeth Warren's meltdown), Ethereum's ZK miracle that could 100x Layer 1 throughput, and Texas launching its own state Bitcoin reserve. Plus, why Stanley Druckenmiller's portfolio strategy might justify going all-in on crypto—and whether alt season is finally on the horizon. ------

3HL - 5-23-25 - Hour 1 - Tennessee Baseball Advances to SEC SemifinalsSee omnystudio.com/listener for privacy information.

Adam Crisafulli of Vital Knowledge and Nicole Webb of Wealth Enhancement Group break down the market action today and whether more pain is ahead. Earnings highlights included results from Workday, Autodesk, Deckers, Ross Stores, and Intuit. Jon sits down for the latest commentary from Intuit CEO Sasan Goodarzi. In Washington, the Trump budget bill took a major step forward—Raymond James policy analyst Ed Mills talks through the implications for investors—including winners and losers. Sean Henry, CEO of logistics firm Stord, on how companies are reshaping supply chains in a new world for global trade. 

In this episode of the Epigenetics Podcast, we talked with Ani Deshpande from Sanford Burnham Prebys about his work on epigenetic regulation and developing small molecules through high throughput screens for AML. Throughout our discussion, we delve into Dr. Despande's journey into the field of biology and science, tracing his evolution from a literature enthusiast in Mumbai to a dedicated cancer researcher. He reflects on his formative experiences during his PhD at Ludwig Maximilian University in Munich, where she developed murine models for refractory acute myeloid leukemia (AML). We examine these models' contributions to therapeutic discovery and understanding the intricate mechanisms underscoring AML's complexities. Transitioning to his postdoctoral work at Scott Armstrong's lab in Boston, Dr. Despande shares his insights on the importance of epigenetic regulators, such as DOT1L, in leukemias, and how they can serve as strategic therapeutic targets. His ambitious pursuit of translational research is further highlighted through his efforts in developing a conditional knockout mouse model and his collaborative work utilizing CRISPR technology to refine our understanding of epigenetic regulation in cancer pathogenesis. Moreover, we engage in a conversation about the challenges and opportunities that arise when establishing his lab at Sanford Burnham Prebys. Dr. Despande candidly discusses the delicate balance between pursuing topics of genuine interest versus adhering to grant fundability, underlining the tension researchers face in the current scientific landscape. His emphasis on the critical need for innovation within lab settings serves as a motivational call for emerging scientists to venture beyond the established templates that often inhibit groundbreaking discoveries. We conclude our dialogue with an exploration of his recent projects, which involve targeting specific epigenetic modifiers and how his lab's findings can contribute to greater understanding and potential treatments for not only AML but also other pediatric cancers driven by gene fusions. Dr. Despande's insights into the integration of modern technologies, such as CRISPR libraries, exemplify his commitment to pushing the boundaries of cancer research. In addition to discussing his scientific contributions, we touch upon Dr. Despande's foray into podcasting (The Discovery Dialogues), shedding light on his motivation to bridge the communication gap between scientists and the broader public. He articulates his desire to demystify scientific discoveries and promote awareness about the intricate journey of research that lays the groundwork for medical advancements. This multidimensional discussion not only highlights his scientific achievements but also emphasizes the importance of effective science communication in fostering public understanding and appreciation of research.   References Deshpande AJ, Cusan M, Rawat VP, Reuter H, Krause A, Pott C, Quintanilla-Martinez L, Kakadia P, Kuchenbauer F, Ahmed F, Delabesse E, Hahn M, Lichter P, Kneba M, Hiddemann W, Macintyre E, Mecucci C, Ludwig WD, Humphries RK, Bohlander SK, Feuring-Buske M, Buske C. Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia. Cancer Cell. 2006 Nov;10(5):363-74. doi: 10.1016/j.ccr.2006.08.023. PMID: 17097559. Deshpande AJ, Deshpande A, Sinha AU, Chen L, Chang J, Cihan A, Fazio M, Chen CW, Zhu N, Koche R, Dzhekieva L, Ibáñez G, Dias S, Banka D, Krivtsov A, Luo M, Roeder RG, Bradner JE, Bernt KM, Armstrong SA. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes. Cancer Cell. 2014 Dec 8;26(6):896-908. doi: 10.1016/j.ccell.2014.10.009. Epub 2014 Nov 20. PMID: 25464900; PMCID: PMC4291116. Sinha S, Barbosa K, Cheng K, Leiserson MDM, Jain P, Deshpande A, Wilson DM 3rd, Ryan BM, Luo J, Ronai ZA, Lee JS, Deshpande AJ, Ruppin E. A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing. Nat Commun. 2021 Nov 11;12(1):6512. doi: 10.1038/s41467-021-26788-6. Erratum in: Nat Commun. 2022 May 16;13(1):2828. doi: 10.1038/s41467-022-30475-5. PMID: 34764240; PMCID: PMC8586238.   Related Episodes Targeting COMPASS to Cure Childhood Leukemia (Ali Shilatifard) The Menin-MLL Complex and Small Molecule Inhibitors (Yadira Soto-Feliciano) MLL Proteins in Mixed-Lineage Leukemia (Yali Dou)   Contact Epigenetics Podcast on Mastodon Epigenetics Podcast on Bluesky Dr. Stefan Dillinger on LinkedIn Active Motif on LinkedIn Active Motif on Bluesky Email: podcast@activemotif.com

Alysa Z. Hutnik, Alexander I. Schneider, Meaghan M. Donahue On April 29, 2025, the Senate Public Safety Committee voted 6-0 to advance legislation that would exempt processing of personal information for a commercial business purpose from coverage by the California Invasion of Privacy Act (CIPA). Three years after extensive wiretapping litigation first emerged targeting the use of website pixels or similar technologies, the amendment could mark the end of the road for a large swath of wiretap litigation in the state and potentially nationwide.

In episode 136 of Cybersecurity Where You Are, Sean Atkinson and Tony Sager are joined live by Lynn Dohm, Executive Director of Women in CyberSecurity (WiCyS). Together, they discuss how WiCyS works to advance women in cybersecurity. Here are some highlights from our episode:01:03. A mission of recruiting, retaining, and advancing women in cybersecurity05:38. How community-focused conferences and scholarships promote community growth06:25. The need to celebrate the work of and encourage support among cyber defenders08:52. Four strategic pillars as a foundation for navigating COVID, societal change, and more13:50. The importance of laying out cybersecurity career paths outside of individual companies15:15. How a foundation of inclusion enables diversity to expand19:45. The use of strategic partners to anticipate changing cybersecurity and hiring needs22:38. Inside the successes of the mentorships and other WiCyS programs28:22. The impact of Alan Paller on opening doors for WiCyS32:35. How volunteerism supports retention in cybersecurity through inclusion and satisfactionResourcesEpisode 77: Data's Value to Decision-Making in CybersecurityEpisode 120: How Contextual Awareness Drives AI GovernanceAlan Paller Laureate ProgramEpisode 30: Solving Cybersecurity at Scale with NonprofitsIf you have some feedback or an idea for an upcoming episode of Cybersecurity Where You Are, let us know by emailing podcast@cisecurity.org.

OKC grabs a 1-0 lead over Minnesota. Sooner baseball advances.

#NEWWORLDREPORT:  MILEI ADVANCES IN BUENOS AIRES JOSEPH HUMIRE @JMHUMIRE @SECUREFREESOC. ERNESTO ARAUJO, FORMER FOREIGN MINISTER REPUBLIC OF BRAZIL. #NEWWORLDREPORTHUMIRE 1939 BUENOS AIRES

Senate advances GENIUS Act CoinMarketCap launches first phase of CMC AI  DigiAsia plans raise to buy BTC Genesis files new lawsuits Learn more about your ad choices. Visit megaphone.fm/adchoices

Understanding Unicornuate Uterus: What It Is, Prevalence, Risks, and a Positive Outlook A unicornuate uterus is a rare congenital condition where the uterus develops with only one half, or "horn," instead of the typical two-horned shape of a normal uterus. This happens during fetal development when one of the Müllerian ducts, which form the uterus, fails to develop fully. As a result, the uterus is smaller, has only one functioning fallopian tube, and may or may not have a rudimentary horn (a small, underdeveloped second horn). This condition falls under the category of Müllerian duct anomalies, which affect the female reproductive tract. For those diagnosed, understanding the condition, its implications, and the potential for a healthy pregnancy can provide reassurance and hope.   What Is a Unicornuate Uterus? The uterus typically forms as a pear-shaped organ with two symmetrical halves that fuse during fetal development. In a unicornuate uterus, only one half develops fully, creating a smaller-than-average uterine cavity. This anomaly can occur with or without a rudimentary horn, which may or may not be connected to the main uterine cavity. If a rudimentary horn is present, it might cause complications like pain if it accumulates menstrual blood, as it often lacks a connection to the cervix or vagina. The condition is often diagnosed during routine imaging, such as an ultrasound, MRI, or hysterosalpingogram (HSG), typically when a woman seeks medical advice for fertility issues, pelvic pain, or irregular menstruation. In some cases, it's discovered incidentally during pregnancy or unrelated medical evaluations.   How Prevalent Is It? Unicornuate uterus is one of the rarest Müllerian duct anomalies, occurring in approximately 0.1% to 0.4% of women in the general population. Among women with Müllerian anomalies, it accounts for about 2% to 13% of cases. The condition is congenital, meaning it's present at birth, but it often goes undiagnosed until adulthood because many women experience no symptoms. Its rarity can make it feel isolating for those diagnosed, but awareness and medical advancements have made it easier to manage and understand. Risks Associated with Unicornuate Uterus While many women with a unicornuate uterus lead healthy lives, the condition can pose challenges, particularly related to fertility and pregnancy. The smaller uterine cavity and reduced endometrial surface area can increase the risk of certain complications, though these are not inevitable. Below are some potential risks: Fertility Challenges: The smaller uterus and single fallopian tube may slightly reduce the chances of conception, especially if the rudimentary horn or other structural issues interfere with ovulation or implantation. However, many women with a unicornuate uterus conceive naturally without intervention. Miscarriage: The limited space in the uterine cavity can increase the risk of miscarriage, particularly in the first trimester. Studies suggest miscarriage rates may be higher (around 20-30%) compared to women with a typical uterus, though exact figures vary. Preterm Birth: The smaller uterus may not accommodate a growing fetus as easily, potentially leading to preterm labor or delivery before 37 weeks. Research indicates preterm birth rates in women with a unicornuate uterus range from 10-20%. Fetal Growth Restriction: The restricted uterine space can sometimes limit fetal growth, leading to low birth weight or intrauterine growth restriction (IUGR). Malpresentation: Babies in a unicornuate uterus may be more likely to position themselves in a breech or transverse position due to the confined space, which could complicate delivery. Cesarean Section: While not mandatory, a cesarean may be recommended in cases of malpresentation, preterm labor, or other complications. However, this is not a universal requirement. Other Complications: Women with a unicornuate uterus may have a higher risk of endometriosis or painful periods, especially if a non-communicating rudimentary horn is present. Kidney abnormalities are also associated with Müllerian anomalies, as the kidneys and reproductive tract develop simultaneously in the fetus. Despite these risks, it's critical to note that not every woman with a unicornuate uterus will experience these complications. With proper medical care, many achieve successful pregnancies and deliveries.   A Positive Outlook: Normal Vaginal Delivery Is Probable The diagnosis of a unicornuate uterus can feel daunting, but it's important to emphasize that a healthy, full-term pregnancy and a normal vaginal delivery are entirely possible. Advances in obstetrics and prenatal care have significantly improved outcomes for women with this condition. Here's why you can remain optimistic: Personalized Care: Working with an experienced obstetrician or maternal-fetal medicine specialist ensures close monitoring throughout pregnancy. Regular ultrasounds can track fetal growth, position, and amniotic fluid levels, allowing for timely interventions if needed. Not Doomed to Cesarean: While some women may need a cesarean due to specific complications, many with a unicornuate uterus deliver vaginally without issue. The decision depends on factors like fetal position, labor progression, and overall health, not the uterine anomaly alone. Full-Term Pregnancies Are Achievable: With careful monitoring, many women carry their pregnancies to term (37-40 weeks). Preterm birth is a risk, but it's not a certainty, and modern neonatal care can support babies born slightly early if needed. Healthy Babies: Countless women with a unicornuate uterus give birth to healthy, thriving babies. The condition does not inherently affect the baby's development or genetic health. Support and Advocacy: Connecting with others who have similar experiences, whether through online communities or support groups, can provide emotional strength and practical advice. Knowing you're not alone can make all the difference. A unicornuate uterus is a rare but manageable condition that requires awareness and, in some cases, specialized care. While there are risks to consider, they are not insurmountable, and many women with this anomaly experience successful pregnancies and vaginal deliveries without complications. With the right support, you can embrace your unique journey, knowing that a unicornuate uterus does not mean you're destined for preterm birth, cesarean delivery, or pregnancy complications. Instead, it's a testament to your resilience and the incredible capabilities of modern medicine to support you every step of the way.   Connect With Us: YouTube: Dive deeper into pregnancy tips and stories atyoutube.com/maternalresources . Instagram: Follow us for daily inspiration and updates at @maternalresources . Facebook: Join our community at facebook.com/IntegrativeOB Tiktok: NatureBack Doc on TikTok Grab Our Book! Check out The NatureBack Method for Birth—your guide to a empowered pregnancy and delivery. Shop now at naturebackbook.myshopify.com .    

Dr. Jameson Taylor, Director of Policy and Legislative Affairs for AFA Action (AFAaction.net), the government affairs affiliate of the American Family Association. He also serves as Senior Fellow for the American Family Association (www.afa.net).  Trump's ‘Big Beautiful Bill' Advances—What's Next?

“Ten years ago, there were relatively few treatment options [for bladder cancer] compared to what we have today which is a relative wealth of options,” said Debasish Sundi, MD, a James urologist and bladder cancer specialist. In this episode, Dr. Sundi explained the function of the bladder (storing urine), the different types of bladder cancer (contained within the bladder and metastatic), how new immunotherapies have led to better options and outcomes, and his research which focuses on identifying the biomarkers in a patient's bladder cancer by analyzing their urine, instead of a more invasive procedure using a scope. There are about 80,000 new cases of bladder cancer diagnosed ever year in the United States and “about 75 to 80 percent are in males,” Dr. Sundi said, adding “the number one cause is exposure to tobacco smoke and tobacco products.” The primary symptom is blood in the urine. “If you see blood in your urine, even if it's just pink, it is worthwhile to talk to your primary care doctor or see a urologist.” Clinical trials have led to the development and approval of several new immunotherapy treatments. “The challenge is we do not have any good biomarkers to tell us how our patients will respond,” Dr. Sundi said. “My lab is developing an assay [test] to non-invasively make an assessment. We've learned that if we look at the immune cells in the urine of someone with bladder cancer, they are similar to the immune cells in their tumor … And this could lead to significantly improving the therapeutic options and helping doctors pick the best medicine for their patients from the start.” Dr. Sundi said his research is motivated by his patients. “When I started in this field the experiences of patients with bladder cancer was something we could and should improve,” he said. “Working toward this is the fuel that is self-sustaining and there is so much excitement in terms of the innovation happening in the bladder-cancer field.”

Global Advances and Persistent Disparities in Lung Cancer Treatment by IASLC

Trump's sweeping tax and spending cuts bill has cleared a key hurdle. Former President Joe Biden and his family are reviewing treatment options for his prostate cancer diagnosis. Severe storms and tornados are set to hit parts of the US today. Police have identified the suspect from the Palm Springs fertility clinic explosion. Plus, a manhunt is underway in New Orleans for seven escaped prisoners. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Bringing 911 intelligence directly into real-time crime centers can help expedite police response when children go missing, retail thefts occur or shots are fired. Advances in technology are making it possible for RTCC analysts to review real-time transcripts and translations of emergency calls, AI-generated call summaries and videos or images from community members. This situational awareness helps officers to better understand what's happening and shave potentially life-saving seconds from their response to emergencies. In this episode of the Policing Matters podcast, part of a special report from Motorola Solutions Summit 2025, host Jim Dudley speaks with Glendale Interim Chief of Police Colby Brandt and Dave Wilson, Retired Assistant Police Chief and Senior Solutions Specialist with Motorola Solutions. They explore how agencies are using technology to expedite the response to community and enterprise-reported 9-1-1 incidents. About our sponsor This episode of the Policing Matters podcast is sponsored by Motorola Solutions.

Moody's becomes the final credit rating agency to downgrade U.S. debt, citing the country's uncertain fiscal path. The White House is downplaying concerns. Meanwhile, investors are taking notice, sending the 30-year bond yield to its highest level since 2023. And later, House Speaker Mike Johnson moves closer to fulfilling his promise to pass former President Trump's "big, beautiful" tax bill — one analysts warn could add $3 to $5 trillion to the national debt over the next ten years.

The House Budget Committee on Sunday night voted to advance a sweeping package with many of President Trump's domestic priorities. But the GOP-led chamber still has hurdles to overcome this week. NPR's Barbara Sprunt reports.Support NPR and hear every episode of Trump's Terms sponsor-free with NPR+. Sign up at plus.npr.org.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Dr. Zach Deutch interviews Dr. Nicole Guinn, guest editor of the June ASA Monitor, and Dr. Steven Frank, contributor, about blood management and transfusion medicine. Listen in as the guests share thoughts on bloodless care, the history of transfusion medicine, patient populations, the possibilities of predictive modeling, and more. Recorded April 2025.

OU Softball advances, OKC Thunder eliminate Denver Nuggets.

Cole Stukenholtz is out this weekend, so Nate Rohr is solo, on location at Baton Rouge, La., as Nebraska softball opens NCAA Tournament. We have full highlights and postgame comments from Rhonda Revelle and Ava Kuszak after the Huskers' 10-2 win over UConn in the first round of the tournament. Plus we break down Husker baseball and look at the strange new format for the Big Ten Tournament. And we take a look at a new recruit for Nebraska Volleyball! GBR!

1 in 10 newborns in the US have congenital heart disease. Advances in early treatment is great news for parents under this stress. Mark talks with Dr. Mathew Elias from Cardiac Center at Children's Hospital of Philadelphia (C.H.O.P.) about procedures and early warning signs, 97% of those born with CHD are expected to reach adulthood. Listen now.

Interview with Mark Selby, CEO of Canada NickelOur previous interview: https://www.cruxinvestor.com/posts/canada-nickel-tsxvcnc-crawford-project-advances-with-feed-completion-eyes-2025-construction-6791Recording date: 13th May 2025Canada Nickel Corporation (TSX: CNC) presents a compelling investment opportunity as it advances North America's most promising nickel project in the face of unprecedented government support and institutional capital returning to the mining sector. CEO Mark Selby's leadership has positioned the company to capitalize on what he describes as "the world's largest nickel sulfide district" in Timmins, Ontario, with the flagship Crawford project now approaching a construction decision after completing its FEED study and progressing through permitting.The company's innovative financing strategy has set it apart during challenging capital markets, executing its fourth successful bridge financing arrangement to avoid dilutive equity raises while maintaining project momentum. Recent financing totaling $39-40 million, including a groundbreaking partnership with TTN First Nation, demonstrates management's ability to access capital through non-traditional channels. This approach recognizes the fundamental shift in mining finance, where actively managed funds have "shrunk very dramatically over the last 15 years" and become concentrated in gold, copper, and silver.Political tailwinds have never been stronger for critical mineral projects in North America. The Trump administration's supply chain security focus, combined with Canada's new government under Carney promising to accelerate critical mineral development, creates multiple funding pathways for projects like Crawford. The Canadian government has established numerous funding programs worth billions, though deployment has been slow until now. With both governments prioritizing critical mineral security and upcoming USMCA renegotiations, Canada Nickel is positioned to benefit from what Selby describes as "monster bold steps forward" in government support.Unlike many nickel companies dependent solely on the EV market, Canada Nickel has strategically designed its operations for market flexibility. The company can direct 100% of production to the stainless steel and alloy markets, which continue to show strong growth (China's 300 series stainless production up 12% year-over-year), while maintaining optionality for EV sales through its Samsung SDI offtake agreement. This diversification provides crucial revenue stability as some automotive manufacturers, including Honda, reassess their EV timelines.Perhaps most significantly for near-term share price performance, generalist institutional investors are returning to mining after a decade-long absence. Selby reports that recent conferences included multiple meetings with generalist funds, representing a fundamental shift from resource-only investors. These funds see relative value in a sector trading at "5 and 10% of NPV" compared to broader markets at high multiples. When generalist capital moves from "0.05% of assets to 0.1% to 0.25%," it creates what Selby describes as "a tidal wave of capital."The company has outlined a comprehensive $3 billion funding package with multiple committed sources including $500 million from Export Development Canada, $600 million in refundable tax credits, $100 million from Samsung, and additional potential funding from European agencies and Canadian government programs. With permitting on track for year-end completion and detailed engineering advancing, Canada Nickel is positioned to make its final investment decision and benefit from first-mover advantage in one of the world's most promising nickel districts.For investors, Canada Nickel represents exposure to critical mineral supply chain security, innovative financing structures, and the convergence of government support with returning institutional interest—all while maintaining operational flexibility that provides downside protection in volatile markets.—View Canada Nickel's company profile: https://www.cruxinvestor.com/companies/canada-nickelSign up for Crux Investor: https://cruxinvestor.com

For a third time in four years, the Edmonton Oilers are off to the NHL's Western Conference Final after dispatching the Vegas Golden Knights in five games of Round 2 action. Be sure to subscribe to the Inside Sports podcast wherever you get your streaming audio and follow Brenden on X at @BrendenEscott. Learn more about your ad choices. Visit megaphone.fm/adchoices

Featuring perspectives from Dr Emmanuel S Antonarakis and Prof Karim Fizazi, including the following topics: Introduction: Quality of Life (0:00) PARP Inhibition (PARPi) (7:15) M0 Disease (23:18) Metastatic Hormone-Sensitive Prostate Cancer (34:33) Radiopharmaceuticals (46:16) Other Novel Investigational Approaches for Metastatic Castration-Resistant Prostate Cancer (54:53) CME information and select publications

In this episode, editor-in-chief Joseph E. Safdieh, MD, FAAN, highlights articles about early studies finding dopamine cellular therapies were safe and tolerable for patients with Parkinson's, use of GLP-1 agonists were associated with reduced dementia risks, and the FDA use of accelerated approvals for several neurology drugs are under scrutiny. 

Sen. Kathleen Kauth's Stand with Women Act, LB89, made it through the second round of debate in the Nebraska Legislature Wednesday evening, but not before an amendment stripped it of a key provision. Sen. Kathleen Kauth's Stand with Women Act, LB89, made it through the second round of debate in the Nebraska Legislature Wednesday evening, but not before an amendment stripped it of a key provision. Sen. Merv Riepe was one of 33 senators to vote for the bill on the first round of debate, but he said he would only advance it further if changes were made. Those changes included removing a requirement for students at K-12 schools and universities to use bathrooms and locker rooms corresponding to their biological sex.

Dr Emmanuel S Antonarakis from the University of Minnesota in Minneapolis and Professor Karim Fizazi from the Institut Gustave Roussy in Villejuif, France, provide their perspectives on relevant new clinical data in prostate cancer and discuss their application to the care of patients. CME information and select publications here.

In this episode of The Effortless Podcast, host Amit Prakash sits down with Professor Debdeep Jena, a leading expert in semiconductors, superconductors, and quantum devices at Cornell University. They explore the fascinating world of quantum computing, from its early 20th-century origins to its transformative potential in modern technology.Professor Jena delves into key concepts of quantum physics and quantum computing, shedding light on quantum systems, qubits, and the challenges and promises of quantum hardware. With decades of experience in semiconductor research, he explains how quantum computing could revolutionize industries, from computational speed to energy efficiency.In this conversation, they discuss:The birth of quantum mechanics and its evolution into quantum computingThe role of qubits and superposition in quantum devicesHow quantum computing is tackling complex problems beyond classical computingCurrent advancements in quantum hardware and the roadblocks still aheadProfessor Jena's perspective on the future of quantum technology and its potential impact on industries like AI, communications, and beyondThis episode is a must-watch for anyone curious about the future of quantum technology and its applications in modern science and industry. Professor Jena provides unique insights into how quantum systems are poised to transform computing, energy efficiency, and even artificial intelligence. Whether you're a tech enthusiast, a student of physics, or a professional exploring the frontier of quantum technology, this conversation is packed with invaluable knowledge.Key Topics & Timestamps:00:00 – Introduction to Quantum Mechanics, Entanglement, and the Role of Information in Physics05:00 – Classical Computation vs. Quantum Computation: Understanding the Basics of Classical and Quantum Bits12:00 – The Role of Information Erasure and Its Link to Energy Loss in Classical Computing18:00 – Superposition and Entanglement: The Basis of Quantum Computation25:00 – Bell's Theorem and the EPR Paradox: Understanding Quantum Nonlocality32:00 – Quantum Measurement and the Challenge of Formulating the Right Questions in Quantum Computation40:00 – Shor's Algorithm and the Promise of Quantum Speedup for Prime Factorization45:00 – Practical Quantum Computing: Grover's Algorithm and the Search Problem52:00 – The Need for Quantum Error Correction and the Problem of Decoherence in Quantum Systems58:00 – Superconducting Qubits: The Technology Behind Quantum Hardware1:05:00 – The Challenges of Packing More Qubits: Coherence Time and Integration of Quantum Systems1:12:00 – Temperature and Cooling Requirements for Superconducting Qubits1:20:00 – Advances in Quantum Error Correction and Strategies for Scaling Quantum Devices1:28:00 – Future Directions for Quantum Computing: Materials Science, Algorithms, and Hardware Innovations1:35:00 – Schrödinger's Cat: Exploring Quantum Superposition in a Philosophical Context1:45:00 – The Double-Slit Experiment: Quantum Interference and the Nature of Quantum Systems1:50:00 – The Future of Quantum Computing: Overcoming Challenges and Expanding Practical Applications2:00:00 – Concluding Thoughts on the Impact of Quantum Mechanics on Modern Technology and the Future of ComputingHosts:Amit Prakash: Co-founder and CTO at ThoughtSpot, former engineer at Google and Microsoft, and expert in distributed systems and machine learning.Guest:Professor Debdeep Jena: David E. Burr Professor of Engineering at Cornell University, expert in semiconductors, superconductors, and quantum devices.Follow the Hosts and Guest:Amit Prakash: LinkedIn | XDebdeep Jena: LinkedInHave questions or thoughts on AI? Drop us a mail at effortlesspodcasthq@gmail.comDon't forget to like, comment, and subscribe for more insightful conversations on the future of technology and innovation!

Join us for a powerful and informative conversation with Kaumudi Bhawe, Founder of YOM Consulting Services, as we explore the latest in brain cancer awareness, diagnosis, and treatment. In this exclusive interview hosted by Madhavi, we shed light on the early signs, evolving therapies, and the importance of timely intervention. Let's raise awareness, dispel myths, and stand in support of those affected. Tune in to TALRadio English on Spotify & Apple Podcast to be informed, inspired, and empowered.Expert : Kaumudi Bhawe, Founder of YOM Consulting ServicesYou Can Reach Kaumudi Bhawe @linkedin.com/in/kaumudi-bhawe-ph-d-7a8114b#TALRadioEnglish #BrainCancerAwareness #CancerSupport #HealingJourney #EarlyDetection #KaumudiBhawe #CancerEducation #BrainHealth #CancerResearch #OncologyAwareness #HopeForHealing #CancerAdvocacy #TogetherWeFight #TouchALife #TALRadio

Inside INdiana Business Radio for the morning of May 15, 2025. The Gary Chicago Airport Authority backs the city's bid for a new Lake County Convention Center. Wawa fans pack into Daleville for the convenience store chain's first Indiana opening. Plus, smart mailbox company Arrive AI starts trading on the NASDAQ. Get the latest business news from throughout the state at InsideINdianaBusiness.com.

President Donald Trump received a lavish welcome in Qatar and the two countries have already announced a deal. The UN is calling for the end of Israel's blockade on Gaza. A portion of Trump's sweeping tax and spending cuts package is a step closer to a full floor vote. The US is pausing the transport of some livestock, to curb the spread of a flesh-burrowing larva. And, there's been another crypto related kidnapping attempt in France. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Nick talks about his recent decision to reenter the world of Private Equity after a six-year hiatus, driven by a desire to align his values with the industry. He reflects on past experiences, including the challenges of value extraction versus value creation, and the personal journey that led to their departure from Private Equity. The discussion highlights the current macro shifts in the market, including the wealth transition of baby boomers and the increasing need for strategic partnerships in private equity. Nick discusses the importance of mentoring and supporting entrepreneurs, advocating for a new model of private equity that focuses on collaboration and shared value creation. KEY TAKEAWAYS There is a significant shift in private equity towards operator-led and founder-led value creation, moving away from merely deploying capital. This evolution presents new opportunities for strategic partnerships with businesses. The retirement of baby boomers is leading to a wave of small-cap and lower mid-market opportunities, creating a pressing need for succession planning and business consolidation. Advances in technology, particularly AI, are transforming business models and enabling service businesses to scale globally, which presents opportunities for founders to leverage these changes for increased value. The aim is to redefine Private Equity as a vehicle for freedom, growth, and shared wealth, emphasising the importance of partnering with entrepreneurs to create mutual value rather than focusing solely on exits. BEST MOMENTS "I decided to leave because of a lot of things that happened during my decade in that industry that didn't align with my values." "I can't sit there saying how bad some of these different situations are... I shouldn't be just throwing stones at something and not trying to fix it." "There's a big explosion of small cap and lower mid-market opportunities... to allow founders to exit gracefully and elegantly is huge." "Entrepreneurship is a team sport at the best of times. You don't want to be the person who's having to pull everything uphill." "My mission around it really is to redefine private equity as a vehicle for freedom and growth and wealth, not just the exit." VALUABLE RESOURCES Scale Your Business Beyond 8 Figures - Watch This Video: https://go.highvalueexit.com/scale-beyond Exit Your Business For Millions - Download This Guide: https://go.highvalueexit.com/opt-in Nick’s LinkedIn: https://highvalueexit.com/li Nick Bradley is a world-renowned author, speaker, and business growth expert, who works with entrepreneurs, business leaders, and investors to build, scale and sell high-value companies. He spent 10+ years working in Private Equity, where he oversaw 100+ acquisitions, 26 exits, and over $5 Billion in combined value created. He has one of the top-ranked business podcasts in the UK (with over 1m downloads in over 130 countries). He now spends his time coaching and consulting business owners in building and scaling high-value business towards life-changing exits. This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/Support the show: https://highvalueexit.com/

Agreements signed by U.S. President Donald Trump and Qatar's Emir Sheikh Tamim bin Hamad Al-Thani on Wednesday will "generate an economic exchange worth at least $1.2 trillion," the White House said in a fact sheet summarizing some of the deals' details. The agreements include a $96 billion deal with Qatar Airways to buy up to 210 Boeing 787 Dreamliner and 777X airplanes with GE Aerospace engines, the fact sheet said.It was markup day for the tax-writing House Ways and Means Committee on May 13—one day after Republicans released the full text of their long-awaited tax legislation—as lawmakers on both sides of the aisle engaged in testy exchanges. The committee pushed the bill forward overnight, passing it along party lines with a 26–19 vote.Sean "Diddy" Combs' criminal trial will enter its third day on Wednesday with his former girlfriend Casandra Ventura expected to resume testifying about how the rapper and hip-hop mogul made her a central figure in his alleged sex trafficking.

Year in Review: Clinical Investigator Perspectives on the Most Relevant New Datasets and Advances in Prostate Cancer | Faculty Presentation 2: Other Available and Emerging Therapeutic Approaches — Emmanuel S Antonarakis, MD CME information and select publications

Andrew Walworth, Tom Bevan and Carl Cannon discuss today's news that the budget bill moved out of the House Ways and Means Committee on a party line vote, and the grand jury indictment of Judge Hannah Duggan on two charges of obstruction of justice that carry a maximum penalty of six years in prison and a $350,000 fine. They also talk about the reaction to the new book “Original Sin” by Jake Tapper and Alex Thompson and a new article by New York Times publisher A.G. Sulzberger. Plus, Homeland Security Secretary Kristi Noem's statement that three Democratic representatives committed felonies while visiting an ICE facility in Newark last Friday. Also, Pete Rose and Shoeless Joe Jackson are deemed eligible for induction in the Baseball Hall of Fame. And finally, Tom Bevan talks to RCP White House correspondent Phil Wegmann about the latest news concerning President Trump's trip to the Middle East.

A bill allowing a lower minimum wage for young workers fell short Wednesday in the Nebraska Legislature, while one trying to regulate foreign agents advanced.

In this short Humanitarian AI Today podcast episode Valentine Pistorozzi speaks with Brent Phillips about Boldcode, new projects in the pipeline, and changes in the way that AI applications are being built. Brent and Valentine speak in detail about Boldcode's https://reporterai.org/ project and about technical aspects of humanitarian AI applications. This interview was recorded as a test in November 2024 to experiment with a short 15 minute interview format for a special series of new Humanitarian AI Today podcast episodes to be published on Mondays.

Our guest today is Dr. Ken Forbus, the Walter P. Murphy Professor of Computer Science and a Professor of Education at Northwestern University. Joining Dr. Ken Ford to co-host today's interview is Dr. James Allen, who was IHMC's associate director until he retired a few years ago. James is a founding fellow of the American Association for Artificial Intelligence and a perfect fit for today's discussion with Dr. Forbus, who, like James, is an AI pioneer.  Back in 2022, James was named a fellow by the Association for Computational Linguistics, an organization that studies computational language processing, another field he helped pioneer. Dr. Forbus also is a Fellow of the Association for the Advancement of Artificial Intelligence and was the inaugural winner of the Herbet A. Simon Prize for Advances in Cognitive Systems. He is well-known for his development of the Structure Mapping Engine. In artificial intelligence and cognitive science, the Structure Mapping Engine is a computer simulation of analogy and similarity comparisons that helped pave the way for computers to reason more like humans. Show Notes: [00:03:07] Ken opens the interview with Dr. Forbus by asking if it is true that he had an unusual hobby for a nerdy kid growing up. [00:04:18] James mentions that Dr. Forbus' family moved often when he was younger and asks how that affected him. [00:05:18] Ken mentions that when Dr. Forbus was in high school, he filled his free time reading about psychology and cognition before eventually coming across some articles on AI. Ken asks Dr. Forbus to talk about this experience and what happened next. [00:07:49] James asks Dr. Forbus if he remembers the first computer he owned. [00:09:17] Ken asks Dr. Forbus if there was anything, other than its reputation, that led him to attend MIT. [00:10:09] James mentions that for the past few decades, Dr. Forbus has been working on developing “human like” AI systems. While much of AI research and development has been focused on meeting the standard of the Turing test, James asks Dr. Forbus why he is not a fan of the Turing test. [00:12:24] Ken mentions that Dr. Forbus received his Ph.D. from MIT in 1984, the same year that Apple released the first Macintosh, which was rolled out with a famous Super Bowl ad. This computer was the first successful mouse driven personal computer with a graphical interface. Ken asks Dr. Forbus what he remembers about that ad, and what his reaction to it was at the time. [00:13:22] James mentions that 1984 was also the year that Dr. Forbus made his first splash in the AI world with his paper on qualitative process theory. James goes on to explain that at the time, qualitative reasoning regarding quantities was a major problem for AI. In his paper, Dr. Forbus proposed qualitative process theory as a representational framework for common sense physical reasoning, arguing that understanding common sense physical reasoning first required understanding of processes and their effects and limits. James asks Dr. Forbus to give an overview of this paper and its significance. [00:18:10] Ken asks Dr. Forbus how it was that he ended up marrying one of his collaborators on the Structure Mapping Engine project, Dedre Gentner. [00:19:14] James explains that Dedre's Structure Mapping Theory explains how people understand and reason about relationships between different situations, which is central to human cognition. James asks Dr. Forbus how Dedre's theory was foundational for the Structure Mapping Engine (SME). [00:25:19] Ken mentions how SME has gone through a number of changes and improvements over the years, as documented in Dr. Forbus' 2016 paper “Extending SME to handle large scale cognitive modeling.” Ken asks, as a cognitive model, what evidence Dr. Forbus has used to argue for the psychological and cognitive plausibility of SME. [00:30:00] Ken explains that many AI systems rely on deep learning,

Congress has officially unveiled its draft legislation for Opportunity Zones 2.0—what's in it, and what's missing? In this episode, Jimmy Atkinson is joined by Jason Watkins of Novogradac to break down the brand new OZ provisions released by the House Ways and Means Committee as part of a larger tax package. They discuss how the proposal would reshape Opportunity Zone designations, introduce rural incentives, and impact timelines for investors and developers. They also highlight key omissions—like interim gains relief and fund-of-funds eligibility—and raise concerns about a potential 2026 “capital freeze” unless major changes are made. Show notes & summary: https://opportunityzones.com/2025/05/oz-legislation-343/

Year in Review: Clinical Investigator Perspectives on the Most Relevant New Datasets and Advances in Prostate Cancer | Faculty Presentation 1: Optimizing the Role of Hormonal Therapy in the Care of Patients with Prostate Cancer (PC) — Professor Karim Fizazi, MD, PhD CME information and select publications

The Nebraska Legislature gave second-round approval Tuesday to a paid sick leave bill that is more restrictive than one voters approved last year.

This week on TABLE TALK, Jeff sat down with Mark Schofield from SB Nation for a fantastic discussion about the 2025 Formula One and Grand Prix season. It was our first discussion about F1 here at the PST podcast show, and and eye-opening interview about how F1 is dominating the sports world. It was a fun discussion with Mark!Topics that Mark and Jeff dove into:- When did the surge of F1 really start happening in our contemporary history, and why has it moved to another level and eshelon in the sports world?- Advances in F1 technology has taken the sport to new heights.- A look at rivalries and where Oscar Piastri's career may be heading after a great start to the 2025 season.- How and why have we seen the growth from McLaren that we've witnessed as their confidence has certainly been boosted this year?All of this and much more this week on Table Talk!SUBSCRIBE on YouTube: youtube.com/@thephiladelphiasportstableHead over to our website for all of our podcasts and more: philadelphiasportstable.comFollow us on BlueSky:Jeff: @jeffwarren.bsky.socialErik: @brickpollitt.bsky.socialFollow us on Threads:Jeff: @mrjeffwarrenErik: @slen1023The Show: @philadelphiasportstableFollow us on Twitter/X:Jeff: @Jeffrey_WarrenErik: @BrickPollittThe Show: @PhiladelphiaPSTFollow us on Instagram:Jeff: @mrjeffwarrenErik: @slen1023The Show: @philadelphiasportstable.Follow Jeff on TikTok: @mrjeffwarrenFollow us on Facebook: facebook.com/PhiladelphiaSportsTable

-Will Bolt elects to start a new Friday night pitcher in Tucker Timmerman tonight against Michigan.  -Huskers fighting for a spot in the BIG Tournament -Nebraska Softball run-rules Penn State on Thursday in the first round of the conference tournament. SPONSORED BY NEBCOOur Sponsors:* Check out Hims: https://hims.com/EARLYBREAKAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Softball advances; Celtics lose big lead againSee omnystudio.com/listener for privacy information.