Podcasts about Major depressive disorder

Join Therapy in a Nutshell's membership and get instant access to all 10 life-changing courses, live weekly Q&As, and a supportive community for just $27/month. Learn how to manage anxiety, process trauma, regulate emotions, and build lasting resilience. Take small, powerful steps toward healing and a richer, more meaningful life. Start your journey today! https://courses.therapyinanutshell.com/membership A lot of people who end up with Major Depressive Disorder have no idea why they feel the way they do. Some have experienced trauma or a huge stressor, but a surprising amount of them say something like, “Everything in my life is fine. I have no reason to be depressed. But I just don't feel happy anymore.” Here's my theory: depression happens when tiny things, often unnoticed, add up over time and become overwhelming. Researchers have explored the brain's “giving up” circuit, which flips from “This is hard, but I'm going to keep trying” to “This is pointless. I'm going to give up.” When life feels too overwhelming, the nervous system reinforces shutdown and hopelessness. This is actually great news because if we can manage just a few of these tiny things, we can remove some of the weight fueling our depression, allowing your brain and body's natural resilience to kick back in. So let's take a look at the micro habits that add up over time to cause depression. Looking for affordable online counseling? My sponsor, BetterHelp, connects you to a licensed professional from the comfort of your own home. Try it now for 10% off your first month: https://betterhelp.com/therapyinanutshell Learn more in one of my in-depth mental health courses: https://courses.therapyinanutshell.com Support my mission on Patreon: https://www.patreon.com/therapyinanutshell Sign up for my newsletter: https://www.therapyinanutshell.com Check out my favorite self-help books: https://kit.co/TherapyinaNutshell/best-self-help-books  Therapy in a Nutshell and the information provided by Emma McAdam are solely intended for informational and entertainment purposes and are not a substitute for advice, diagnosis, or treatment regarding medical or mental health conditions. Although Emma McAdam is a licensed marriage and family therapist, the views expressed on this site or any related content should not be taken for medical or psychiatric advice. Always consult your physician before making any decisions related to your physical or mental health. In therapy I use a combination of Acceptance and Commitment Therapy, Systems Theory, positive psychology, and a bio-psycho-social approach to treating mental illness and other challenges we all face in life. The ideas from my videos are frequently adapted from multiple sources. Many of them come from Acceptance and Commitment Therapy, especially the work of Steven Hayes, Jason Luoma, and Russ Harris. The sections on stress and the mind-body connection derive from the work of Stephen Porges (the Polyvagal theory), Peter Levine (Somatic Experiencing) Francine Shapiro (EMDR), and Bessel Van Der Kolk. I also rely heavily on the work of the Arbinger Institute for my overall understanding of our ability to choose our life's direction. And deeper than all of that, the Gospel of Jesus Christ orients my personal worldview and sense of security, peace, hope, and love https://www.churchofjesuschrist.org/comeuntochrist/believe If you are in crisis, please contact the National Suicide Prevention Hotline at https://suicidepreventionlifeline.org or 1-800-273-TALK (8255) or your local emergency services. Copyright Therapy in a Nutshell, LLC

Thanks to our sponsor, Venice.AI. Get 20% off a pro plan using our link: venice.ai/coolstuff and code coolstuff. New ketamine study promises extended relief for depression The mystery of lightning may finally be solved Infrared contact lenses let people see in the dark – or with their eyes closed Apple's iPhone Update—Why You Need To Change Your Messaging App Contact the Show: coolstuffcommute@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Learn more about new and emerging adjunctive treatments for major depressive disorder (MDD).  Credit available for this activity expires: 05/13/2026Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/new-and-emerging-adjunctive-treatments-major-depressive-2025a1000bbh?ecd=bdc_podcast_libsyn_mscpedu

Interview with Richard B. Lipton, MD, author of Fremanezumab for the Treatment of Patients With Migraine and Comorbid Major Depressive Disorder. Hosted by Cynthia E. Armand, MD. Related Content: Fremanezumab for the Treatment of Patients With Migraine and Comorbid Major Depressive Disorder

Interview with Richard B. Lipton, MD, author of Fremanezumab for the Treatment of Patients With Migraine and Comorbid Major Depressive Disorder. Hosted by Cynthia E. Armand, MD. Related Content: Fremanezumab for the Treatment of Patients With Migraine and Comorbid Major Depressive Disorder

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This short episode is about counselling patients on antidepressant medications.Hosts: Matthew Cho and Angad SinghAudio editing: Angad SinghTime Stamps:2:03 - Steps to antidepressant counselling7:31 - Frequently asked questions about antidepressantsRelated Episodes:PsychEd Episode 1: Diagnosis of Depression with Dr. Ilana ShawnPsychEd Episode 2: Treatment of Depression with Dr. Sidney KennedyPsychEd Episode 58: Depression in Children and Adolescents with Dr. Darren CourtneyPatient Education:UpToDate resource on ‘Medicines for Depression': https://www.uptodate.com/contents/medicines-for-depression-the-basicsCAMH resource on ‘Antidepressant Medications':https://www.camh.ca/en/health-info/mental-illness-and-addiction-index/antidepressant-medicationsKelty Mental Health resource on ‘Selective Serotonin Reuptake Inhibitors': https://keltymentalhealth.ca/sites/default/files/resources/SSRI_MedicationSheet2022.pdf, References:PsychDB. (2024, January 11). Introduction to Antidepressants. https://www.psychdb.com/meds/antidepressants/homeLam RW, Kennedy SH, Adams C, Bahji A, Beaulieu S, Bhat V, Blier P, Blumberger DM, Brietzke E, Chakrabarty T, Do A. Canadian Network for Mood and Anxiety Treatments (CANMAT) 2023 Update on Clinical Guidelines for Management of Major Depressive Disorder in Adults: Réseau canadien pour les traitements de l'humeur et de l'anxiété (CANMAT) 2023: Mise à jour des lignes directrices cliniques pour la prise en charge du trouble dépressif majeur chez les adultes. The Canadian Journal of Psychiatry. 2024 Sep;69(9):641-87.Contact:For more about PsychEd follow us on Instagram (@psyched.podcast),  Facebook (PsychEd Podcast), and X (@psychedpodcast). You can email us at psychedpodcast@gmail.com and visit our website at psychedpodcast.org.

Q-BANK: https://patreon.com/highyieldfamilymedicineIntro (0:35),Major Depressive Disorder (1:57),Other mood disorders (7:50),Bipolar Disorder (12:58),Anxiety disorders (18:33),Psychotic disorders (25:36),Personality disorders (30:55),Psychiatric emergencies (36:36),Practice questions (42:24)

Feeling down from time to time is normal, but how can you tell when sadness is something more – like major depressive disorder? We spoke with Jessi Gold, MD, MS, the first chief wellness officer of the University of Tennessee system and bestselling author of How Do You Feel?, to unpack the complexities of depression. She breaks down the differences between temporary low mood and clinical depression, the role of genetics and medical conditions, and how daily stressors can contribute. We also dive into treatment options -- from therapy to medication -- and the importance of recognizing when it's time to seek help.

With depression being one of the most common mental health conditions in the world, a lot of a clinical psychologist's workload will be supporting people with depression. A common depression symptom is what's known as “Leaden Paralysis” and one of the effects of the symptoms is that everyday tasks take a million times more energy to complete. This can make the “simple” task of getting out of bed feel impossible for people with depression. Therefore, in this clinical psychology podcast episode, you'll learn what is leaden paralysis, why leaden paralysis impacts people's mental health and what to do when depression makes it impossible to get out of bed. If you enjoy learning about mental health, Major Depressive Disorder and psychotherapy then this will be a great episode for you.In the psychology news section, you'll learn how patience is a coping strategy and not a virtue, why non-human animals also see shrinking social circles in old age, and how access to effective mental health treatment is scarce worldwide.LISTEN NOW!If you want to support the podcast, please check out:FREE AND EXCLUSIVE 8 PSYCHOLOGY BOOK BOXSET- https://www.subscribepage.io/psychologyboxsetCBT For Depression: A Clinical Psychology Introduction To Cognitive Behavioural Therapy For Depression- https://www.connorwhiteley.net/cbt-for-depression Available from all major eBook retailers and you can order the paperback and hardback copies from Amazon, your local bookstore and local library, if you request it. Also available as an AI-narrated audiobook from selected audiobook platforms and libraries systems. For example, Kobo, Spotify, Barnes and Noble, Google Play, Overdrive, Baker and Taylor and Bibliotheca. Patreon- patreon.com/ThePsychologyWorldPodcast#depression #majordepressivedisorder #leadenparalysis #psychotherapy #clinicalpsychology #mentalhealth #clinicalmentalhealth #clinicalpsychologist #mentalhealthawareness #mentalhealthsupport #mentalhealthadvocate #psychology #psychology_facts #psychologyfacts #psychologyfact #psychologystudent #psychologystudents #podcast #podcasts

The Ottawa Hospital's mental health program provides early diagnosis and treatment of severe mental illness. Major depressive disorder is a mental health condition in which someone is feeling very low and not able to enjoy things the way they normally would over a prolonged period. It's persistent and can go on for months or even years but there is hope. In this episode, we learn more about depression with Dr. Andrew Greene, a psychiatrist at The Ottawa Hospital. (19:42)       If you know someone who may be suffering from depression and needs help, the best place to start is by visiting your family doctor. If you don't have access to a family doctor, you can go to AccessMHA.ca. 

Jennifer is a single mom and entrepreneur who lives with Complex PTSD and Major Depressive Disorder from childhood trauma. Throughout her life, Jen has learned valuable coping skills and has made it her mission to help others to better understand their own emotions.  Jen has faced obstacles in her healing journey - from becoming a mother without a healthy parental model of her own to overcoming her inner saboteur while coping with the symptoms of CPTSD and Depression.  She has spent the last 4 years developing My Moody Monster - a pull apart plush toy that has helped children to get out their frustrations in a safe way and giving families a tool to talk about emotions and communication.  Jen believes by sharing her own story she can help others to know they are not alone. Her YouTube channel features her Moody Talks focusing on an emotion each month and teaching coping skills that have helped her with her own mental health. Instagram: http://www.instagram.com/mymoodymonster  Facebook: http://www.facebook.com/my-moody-monster  TikTok: http://www.tiktok.com/@mymoodymonster   Linkedin: https://www.linkedin.com/company/93141440 Website: http://www.mymoodymonster.comYouTube: http://www.youtube.com/@mymoodymonster  Cody's content: https://linktr.ee/cjones803 #podcast #purewisdompodcast #personalgrowth #motivation #mindset #facingfears #selfidentity #inspiration #selfimprovement #psychology #entrepreneurship #fitness #fitnessmotivation #business #career #dating #relationships #lifecoach #healthandwellness #workout #coaching Disclaimer: Any information discussed in this podcast is for entertainment purposes only and is not intended to act as a substitute for professional, medical, legal, educational, or financial advice. The following views and opinions are those of the individual and are not representative views or opinions of their company or organization. The views and opinions shared are intended only to inform, and discretion and professional assistance should be utilized when attempting any of the ideas discussed. Pure Wisdom Podcast, LLC, its host, its guest, or any company participating in advertising through this podcast is not responsible for comments generated by viewers which may be offensive or otherwise distasteful. Any content or conversation in this podcast is completely original and not inspired by any other platform or content creator. Any resemblance to another platform or content creator is purely coincidental and unintentional. No content or topics discussed in this podcast are intended to be offensive or hurtful. Pure Wisdom Podcast, LLC, its host, its guest, or any company participating in advertising through this podcast is not responsible for any misuse of this content.

Today, The Frontier Psychatrists welcomes back my friend Ben Spielberg. He's been a reader for a long time and has contributed to the newsletter in the past. It was on Clinical Trial design, a perennial favorite around these parts.With only light edits, what follows is his work, narrated by me, for the Audio Version.I would invite you to the live class today on working as an out-of-network provider, but it sold out last night, so you'll have to wait for the next one. My prior article on Spravato is available here.The year is 2024. OpenAI has just launched its latest update to ChatGPT, promising more natural and less artificial-sounding language. Donald Trump has won the nomination for President of the United States. Another chain of ketamine clinics has engaged in a corporate reorganization. There is conflict in the Middle East. Are we sure that we're not living Groundhog's Day?I am the founder of Bespoke Treatment, an integrative mental health facility with multiple locations that has at times been referred to as a "ketamine clinic." I have also seen countless so-called "ketamine clinics" sell for pennies on the dollar and go bankrupt seemingly overnight. In this case, Numinus, a company that was publicly traded in Canada and owned a number of psychiatric clinics specializing in ketamine in the US and Canada, has sold its clinics to Stella (a company that has stealthily become one of the larger mental health providers in the country and is the first to bring the awesome SGB treatment to scale). It's not the first time this has happened. It's not the second, nor the third, nor even the fourth time this has happened. But yet, the common consensus is that ketamine clinics are a cheap, easy business with recurring revenue. So, what gives?Figure 1. A reddit user asking anesthesiologists if they should start a ketamine or Botox clinic for easy cash on the side. Does this make you feel gross? Should it?The Ketamine Clinic Model 101The most basic outline for a ketamine clinic is as follows: a provider rents an office space with, on average, five or so exam rooms. They buy equipment for infusions like a pump, catheter, needles, and syringes. They buy some comfortable recliner chairs. They hire a receptionist to answer phones, field patient questions, charge credit cards, and handle medical record requests. They hire a nurse to insert the IV, monitor vital signs, check blood pressure, juggle multiple patients at once, and make sure the ketamine is flowing into patients' veins unencumbered. Two SKUs are typically offered: ketamine infusions for mood, which last approximately 40 minutes, and ketamine infusions for pain, which last for up to 4 hours. Zofran is offered for nausea, and some clinics have fun add-ons like magnesium or NAD. An average mood infusion costs around $400-$500 in a medium cost-of-living area, while mood-infusions can run up to $700 in a higher cost-of-living area. Some clinics offer package discounts if patients buy six or more upfront, which helps with cash flow for the clinic (cash now is better than cash later, of course).A Note on Scope of PracticeThe first wave of ketamine clinics was started mainly by providers who were not mental health specialists. Instead, they were owned by anesthesiologists, ER physicians, and sometimes CRNAs. These providers were especially experienced with ketamine in hospital settings, as well as setting up infusions. Psychiatrists, on the other hand, do not usually order infusions in outpatient settings, and very few had actual hands-on experience with ketamine in practice. That being said, there are a number of variations to the model above: psychiatrist-owned ketamine clinics would often prefer to use intramuscular injections in lieu of infusions, but 2-3 injections would have to be given during a single session for mood and pain sessions were out of the question. Other ways to save costs might include having an EMT do the actual injections (this is highly state-dependent), asking nurses or MAs to work the front desk, or working a full-time regular doctor job. In contrast, your nurses run the actual ketamine services via standing orders, a written document that details routine and emergent instructions for the clinic.Some clinics offer full evaluations prior to rendering treatment, but many offer a simple brief screening on the phone to check for contraindications before scheduling a patient for their first session. The clinics owned by psychiatrists have historically been a bit more thorough in terms of the initial psychiatric evaluations, given that they can actually perform initial psychiatric evaluations within their respective scope of practice. Sometimes clinics may have therapists on-site who can render ketamine assisted therapy (meaning, therapy occurring concurrently) for an additional $100-$300. Otherwise, there is not much decision-making that goes on— other than deciding on medication dosages. Most infusions start off at .5mg/kg of body weight, which is by far the most evidence-based dosage. In practice, most clinics increase dosage every session because even though ketamine is considered to be a weight-based medicine for anesthesia, there is thought to be a “sweet spot” of dosage for everyone, if one can imagine an inverted U shape curved, where the ideal dosage for each patient is at the tippity-top of the inversion. Dosage increases are highly variable depending on the clinic: some have a maximum dosage, some will only increase a certain percentage, and some may even use standardized increments (e.g., only offering dosages in increments of 50mg). A typical series of infusions is 6-8 over 3-4 weeks, followed by boosters as needed.Fool's GoldAt first glance, the business model seems fantastic. As a cash business, there are no AR issues, no third party billing companies to deal with, and no prior authorizations to fight over. Sure, the cost is high, but it's not that high compared to many other healthcare services. Since the benefits fade over time, a ketamine clinic has built-in recurring revenue from patients every week, month, quarter, or year – it's like a subscription business! Ketamine is trendy and sexy; TV shows like White Lotus mention it, and ravers from the 90's recall it with great fondness. Unlike SSRIs and psychotherapy, ketamine works for depression fast. It's amongst the fastest treatments for depression that we have today, and there are a lot of depressed people. It can help someone out of debilitating depression in 40 minutes. It has none of the un-sexy side effects of SSRIs like sexual dysfunction, gastrointestinal discomfort, or uncontrollable sweating. Instead, it has sexy side effects: euphoria, hallucinations, and feelings of unity with the universe. Also, unlike SSRIs, it helps most people who try it. It really is an amazing treatment, and I often feel grateful that my clinic is able to offer it to patients in needFigure 2. Most business-savvy reddit user.Supply and Demand… or SomethingMood disorders disproportionately affect individuals who are of lower socioeconomic status compared to individuals with a lot of disposable income. Of course, wealthier individuals are no more immune to mental health disorders than anyone else, but the main target market that benefits most from ketamine just do not have the means to afford it. They don't have $3,000 to burn on yet another treatment that may or may not work. Often, the patients who could really use a series of ketamine infusions cannot scrounge enough money for a single infusion, let alone a whole series and prn boosters. However, there should be enough depressed people with cash to throw around out there… right?Wait, Isn't That A Horse Tranquilizer?Of course, ketamine clinics can find more patients via marketing and advertising. However, I've found that many medical doctors who see this population, like primary care providers, are not up to date with the research. When I first launched my company, I used to go door-to-door to medical buildings in Santa Monica with cookies to speak with them about advancements in interventional psychiatry. I cannot count the number of times that I was laughed out of each office; referring providers are risk-averse, and the perception of ketamine has traditionally been poor. Medical doctors would exclaim, “Of course people feel better; you're getting them high,” and lament that I was administering a drug thought to be highly addictive. Psychotherapists, who would also be fantastic referral partners, generally refer to psychiatry, but it's less common for them to refer to specific treatments. Nowadays, psychotherapists who are particularly invested in ketamine can sign up with venture-backed companies like Journey Clinical and render their own ketamine-assisted psychotherapy with some prescriber supervision. The issue is that despite the media attention, people with depression don't read innovative health newsletters, nor do they review papers in scientific journals. They rely on information from their psychiatrists, medication management providers, and psychotherapists. If they are not told that this is an option for them, they won't hear about it without ad spend. Oh yeah, and there is a major issue with ad spend: the word ketamine itself is a restricted drug term, and legitimate clinics routinely get banned from Google and Meta for mentioning it, which makes digital advertising more difficult than it would be for any other legitimate service.The Matthew Perry EffectKetamine is very desirable for some patients (unfortunately, sometimes the patients who want it most are frankly the worst candidates for it), but I'd wager that the majority of patients who need it are kind of scared of it. They want to feel good, they want relief from depression and trauma, but it's a weird thing to do a drug that is a horse tranquilizer and also an anesthetic in a reclining chair in a medical office that tricks your brain into feeling like you're dead for a little bit. It's kind of far off from acupuncture and more traditional alternative medicine. There is certainly a non-zero addictive potential that needs to be carefully weighed, it's not a particularly comfortable experience for many patients—especially those with a history of trauma—even if it helps after the experience is over. Additionally, the famous actor from the most famous show in the world, who was deemed to have a cause of death relating to ketamine, isn't exactly helping mass adoption. Overall, this just makes marketing and advertising even more expensive, because a) the majority of referring providers are skeptical, b) patients can't pay for it and c) patients who can pay for it are cautious.Disruptive Business ModelsIn the model I've described above, there are 3 sets of cost centers: rent, staff, and marketing. In some areas of the country, rent may be negligible, and in others, it is quite high. Like an owner-operated restaurant, if a clinic is owned by a company that is not a clinician, they have to find one and pay for one. Venture-backed companies like Mindbloom, Better U, and Joyous have also created entire businesses on the back of the COVID-era controlled substance waivers, whereby they send patients ketamine tablets and/or lozenges directly through the mail. Unlike the clinic model, they don't have rent to pay, and since national marketing campaigns are often cheaper than hyper-local brick and mortar campaigns, they are able to find new patients at lower acquisition costs compared to their clinic counterparts. Some patients do extensive research before treatment and only want to find IV clinics that offer specific dosages, but many are fine with the cheapest ketamine possible, and would prefer to pay as low as $150 for an entire month compared to $3,000.Figure 3. Did you sign up for a discounted ketamine subscription on Black Friday after purchasing a new flat-screen TV?Spravato: Coming In HotJohnson & Johnson's branded esketamine (note the prefix es) is on track to reach coveted “blockbuster status.” While it was FDA approved for Major Depressive Disorder in 2019, it took some time to catch on for a number of reasons including skepticism that the added es only added to pharma pockets and didn't actually work, health insurance companies taking time to decide on what their medical necessity criteria should be, and social isolation due to COVID-19 being a thing. My clinic has become one of the larger Spravato providers in the Los Angeles area, and while we still offer ketamine infusions, our infusion census has decreased by over 70%. The scenario is this: a patient with severe depression comes in to see us, they've heard about ketamine, but they find out that Spravato is covered by insurance for a $20 copay. Maybe ketamine has slightly better efficacy (which, in my opinion, is really just a function of being able to adjust dosage). Still, patients would prefer paying a lot less money to receive almost-the-same benefits.Death By A Thousand SticksThere are a number of other issues with the model that become problematic, especially at scale. Large medical distributors like McKesson and Henry Shein have instituted CYA policies, limiting ketamine sales to licensed anesthesiologists. Medical malpractice carriers alike have followed suit, requesting detailed addendums from providers regarding their ketamine training or flat-out refusing coverage for anyone who isn't an anesthesiologist. Since controlled substance manufacturing is directed by the DEA based on their own predictions, it's not uncommon for ketamine to go on shortage for weeks to months at a time. There are a myriad of problems with the model of point solutions which have been detailed here already, but in short, the old adage rings true: if all you have is a hammer, everything looks like a nail, and if all you have is ketamine, everything looks like a juicy vein. But while ketamine is a highly efficacious treatment, it's not the best treatment for everyone, and patients can become downright dysregulated after ketamine, which a clinic in this model just can't handle adequately at scale. And ultimately, methods to do everything cheaper don't work out that well. For example, putting multiple patients in one room may seem like a good idea, but it is ultimately not conducive to the actual ketamine experience. Any sort of vertical integration also adds an insurmountable amount of complexity, like starting to offer Spravato or TMS, because now they have to start accepting insurance, become in-network, manage billing and AR, and so on. Depending on location and the clinic set-up, they also require specialized providers onsite.Figure 4. Supply chain issues abound.Insurance IssuesSome patients try to be well-informed. They, rightly or otherwise, don't believe everything they hear from their providers, so they call up their health insurance companies and ask. They just call the phone number on the back of the card and ask the representative if ketamine infusions are covered. Undoubtedly, the representative says yes—even though many insurance companies have published guidelines that explicitly deny any coverage for ketamine for a mental health disorder. These patients come in frustrated, distrustful of their providers and reaffirms their belief that ketamine clinics are just cash grabs. Even if one manages to obtain a coveted insurance contract for ketamine, like Ketamine Wellness Centers had with the VA, it kickstarts cashflow and complexity issues that scale should sort out, but ultimately doesn't because of the aforementioned issues above.Overall, it is possible to have a successful ketamine clinic in 2024. Still, it isn't easy due to market conditions, the population served, and the ever-changing landscape of mental health treatment. While many successful clinics exist today, the wheels tend to start to fall off when scaling, where all of a sudden, a clinic's reach has surpassed its captive population. Otherwise, it becomes a series of continual cost-cutting until there is nothing left to cut… save for the business itself.Ben Spielberg is the Founder and Chief Executive Officer of Bespoke Treatment, a comprehensive mental health facility with offices in Los Angeles, CA, and Las Vegas, NV. He is also a PhD Candidate in Cognitive Neuroscience at Maastricht University.For more on psychiatric medications, buy my book Inessential Pharmacology. (amazon link).For pieces by other TFP contributors, follow:Alex Mendelsohn, Michelle Bernabe, RN, @Psych Fox, Carlene MacMillan, MD, David Carreon, M.D., Benjamin Lippmann, DO, Awais Aftab, Courtny Hopen BSN, HNB-BC, CRRN, Leon Macfayden and many others! The Frontier Psychiatrists is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit thefrontierpsychiatrists.substack.com/subscribe

Credits: 0.50 AMA PRA Category 1 Credit™, 0.50 ABIM MOC or 0.41 AANP, including 0.41 AANP Pharm   CME/CE Information and Claim Credit: https://www.pri-med.com/online-cme-ce/Podcast/when-ssris-are-not-enough  Overview: In this podcast, expert faculty will discuss how the heterogeneity of major depressive disorder (MDD) symptoms, the frequency of residual symptoms, and the common occurrence of treatment-resistant depression (TRD) indicate a pathophysiology that is complex and multifactorial. The faculty will provide an overview of the current understanding of MDD pathophysiology and discuss how current standard-of-care treatments often fail to comprehensively target these mechanisms, emphasizing how future treatment developments can focus on under-addressed pathophysiological mechanisms, paving the way for personalized MDD treatments that target individual symptom profiles. 

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.Takeda, Roche, and Gilead have recently made significant deals in the pharmaceutical industry. Takeda's investment of up to $1.3 billion in Keros' blood cancer anemia drug is making waves, potentially challenging Bristol Myers Squibb. Roche has joined forces with Cour in a deal focused on autoimmune diseases, valued at over $900 million. Meanwhile, Gilead is reentering the ADC space with a potential $415 million license agreement.In other news, Intra-Cellular is seeking approval for Caplyta in major depressive disorder, a move that could result in $1 billion in sales. Unfortunately, Alligator has been forced to reduce its staff by 70% due to capital constraints. On a brighter note, Biocon has received FDA approval for a biosimilar to J&J's Stelara, and Applied Therapeutics is making strides in the fight against deadly brain cancer.However, Bluebird's gene therapy Skysona is currently under FDA safety probe for hematologic malignancies, raising concerns within the industry. Despite this setback, the pharmaceutical industry as a whole continues to see growth and innovation on multiple fronts.

In this highly anticipated follow-up, we welcome back Jon Nelson, the man who went from battling relentless, treatment-resistant depression to becoming a pioneering advocate for mental health. Jon's journey with deep brain stimulation (DBS) wasn't just a breakthrough; it was a total game-changer. Now, with “robots in his head” pumping 23 million pulses a day, Jon's mission has evolved from mere survival to a full-throttle campaign to ‘Pulverize the Stigma.' We delve into the shocking realities of stigma, outdated treatments, the price of mental illness on families, and how a bold middle finger to societal norms is long overdue.SHOW NOTESIntroduction: Matt recaps Jon's #1 episode, "Robots in My Head," and introduces Jon's latest campaign, "Pulverize the Stigma."The Fight Continues: Jon discusses the post-DBS journey and why stigma remains a public health crisis.From Suicidal Ideation to Mission Mode: Jon shares his transformation from survival to advocacy, fueled by the urgency to make people understand mental illness as a brain disease.Systemic Failures: They tackle the stigma, the lack of insurance support, and how recent government funding cuts to mental health research could set progress back decades.The Reality of Stigma: Jon paints a visceral picture of what it's like to live with depression and how society's dismissive attitude does real harm.Empathy as a Cure: The impact of compassion, kindness, and simple human gestures—why they can be more effective than therapy or meds.Final Thoughts and Resources: Jon offers powerful calls to action and provides resources for listeners, including his new site, PulverizeTheStigma.com, and the nonprofit One Mind.RELATED LINKSJon's First Episode: "Robots In My Head: Deep Brain Stimulation"Jon's Website"Jon Nelson: Five Things I Wish Someone Told Me When I Was First Diagnosed With Mental Illness""Today's Depression Treatments Don't Help Everyone""#37: Jon Nelson – DBS for Depression Saved My Life: Defying Stigma in Mental Health"See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Learn about atypical antipsychotics and the best strategies for using them to augment treatment for major depressive disorder (MDD) with inadequate response to initial therapy.   Credit available for this activity expires: 11/27/2025 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/expert-update-current-and-emerging-pharmacotherapies-2024a1000lkl?ecd=bdc_podcast_libsyn_mscpedu

Interview with Benoit H. Mulsant, MD, MS, and Tarek K. Rajji, MD, authors of Slowing Cognitive Decline in Major Depressive Disorder and Mild Cognitive Impairment: A Randomized Clinical Trial. Hosted by John Torous, MD, MBI. Related Content: Slowing Cognitive Decline in Major Depressive Disorder and Mild Cognitive Impairment

Interview with Benoit H. Mulsant, MD, MS, and Tarek K. Rajji, MD, authors of Slowing Cognitive Decline in Major Depressive Disorder and Mild Cognitive Impairment: A Randomized Clinical Trial. Hosted by John Torous, MD, MBI. Related Content: Slowing Cognitive Decline in Major Depressive Disorder and Mild Cognitive Impairment

Did you know, there is a physical transfer of energy when sunlight hits our bodies? Without light, there is no life! On this episode of Vitality Radio, Jared welcomes back Suzanne Bates, one of our own at Vitality Nutrition. Previously she told her story about how she reversed her own heart failure, diabetes, severe depression and more using natural means. Here Suzanne shares her experience challenging herself to 100 Days of Light and what role that played in her healing journey. She and Jared discuss the incredible benefits of sunlight on mental and physical health. You'll also learn how to incorporate stillness, gratitude, and grounding into a sunlight practice and how to challenge yourself the way Suzanne did and see big changes in your own life!Challenge:*Every day in October, go outside at sunrise for 15-30 minutes! *Look up towards the brighter part of the sky for 10 seconds (Never look directly at the sun!)*Attempt to be still for 5-10 minutes*Incorporate the practice of gratitudeShare your experiences and gain support by becoming part of the Facebook community:Get Up! Get Out! Get Happy! Additional Information:#442: Against the Odds - A Story of Hope and Healing with Suzanne Bates#378: Emotional Vitality: Using Curiosity to Take Back Control of Your Subconscious MindGet Up! Get Out! Get Happy! - Facebook groupVisit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Please also join us on the Dearly Discarded Podcast with Jared St. Clair.Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

Abby and Patrick welcome labor journalist Sarah Jaffe – author of Necessary Trouble and Work Won't Love You Back – for her first interview about her forthcoming book, From the Ashes: Grief and Revolution in a World on Fire. From the Ashes is at once a deeply personal narrative and a wide-ranging journey of searing reportage on the lives and struggles of individuals and communities. Sarah, Abby, and Patrick take on the overdeterminations of loss, grief, mourning, and memorialization from contemporary political discourse to Freud's classic “Mourning and Melancholia.” In what ways can individual experiences of grief be fundamentally singular and yet also sites of collective solidarity and social transformation? What are the norms, narratives, and timelines that get imposed on expressions of psychic pain in the wake of loss, from the DSM to Human Resources to newspaper headlines? How does the experience of loss differ when the lost object in question isn't necessarily a person, but a place, an ideal, intergenerational links, or expectations for a now-foreclosed future instead?Details about From the Ashes are here: https://www.hachettebookgroup.com/titles/sarah-jaffe/from-the-ashes/9781541703490/ and the book is available for preorder here: https://hachettebookgroup.formstack.com/forms/fromtheashes (use code FTA20 for 20% off, plus bonus content)Sarah's website is here: https://sarahljaffe.com/Key texts cited in the episode:Freud, “Mourning and Melancholia”Freud, “On Transience”Jacqueline Rose, “Virginia Woolf and the Death of Modernism”Namwali Serpell, The FurrowsHave you noticed that Freud is back? Got questions about psychoanalysis? Or maybe you've traversed the fantasy and lived to tell the tale? Leave us a voicemail! 484 775-0107  A podcast about psychoanalysis, politics, pop culture, and the ways we suffer now. New episodes on Saturdays. Follow us on social media:  Linktree: https://linktr.ee/OrdinaryUnhappiness Twitter: @UnhappinessPod Instagram: @OrdinaryUnhappiness Patreon: patreon.com/OrdinaryUnhappiness Theme song: Formal Chicken - Gnossienne No. 1 https://open.spotify.com/album/2MIIYnbyLqriV3vrpUTxxO Provided by Fruits Music

Today we're diving deep into the world of big feelings. Emotions can be overwhelming for anyone, but learning to manage them is crucial, especially when it comes to guiding our children and grandchildren and providing them with tools to help them process, communicate and heal.In this episode, we have a special guest, Jennifer Ginty. Jen is a single mom, entrepreneur, and mental health advocate who has bravely navigated life with Complex PTSD and Major Depressive Disorder resulting from childhood trauma. Despite these challenges, Jen has emerged stronger and is now on a mission to help others understand and manage their emotions through her YouTube channel and unique creation "Moody Monster."Key Discussion Points:Jen's Personal Journey: Jen shares her back story with abuse that led to Complex PTSD and Major Depressive Disorder. She discusses the obstacles she faced and the coping skills she developed along the way.Introducing "My Moody Monster": Discover the inspiration behind Jen's innovative creation, "My Moody Monster," and how it serves as a tool for emotional education and well-being.Misconceptions About Big Feelings: Jen addresses common misunderstandings about managing emotions and shares how she overcame them.Societal Influences on Emotional Perception: We explore how societal factors shape our views on emotions and Jen offers advice on navigating these influences.Practical Advice for Emotional Overwhelm: Jen provides actionable tips for those feeling overwhelmed by their emotions, offering a starting point for managing them. Keep the conversation going - Join us for more insightful conversations in the Message in the Middle Private Facebook Community & subscribe to Message in the Middle podcast on your favorite listening platform. Connect with Marianne:Website: Message In The Middle with MarianneMessage In the Middle Facebook Group: https://www.facebook.com/groups/422430469323847/YouTube: https://www.youtube.com/@MessageInTheMiddle/playlistsEmail: Contact | Message In The Middle with MarianneSubscribe to Message In the Middle: Apple Podcasts Spotify

In this episode, we review the high-yield topic of ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Major Depressive Disorder ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Psychiatry section. Follow ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets Linkedin: https://www.linkedin.com/company/medbullets

What do you do when your patients are unravelling due to their antidepressant?   Credit available for this activity expires: 7/26/2025 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1001393?ecd=bdc_podcast_libsyn_mscpedu

Today, we're going to talk about virtual reality and how it could be used to treat depression. We're talking with psychiatrist Kim Bullock, the founding director of Stanford's Neurobehavioral Clinic and Virtual Reality & Immersive Technologies (VRIT) program. Dr. Bullock — a physician certified in Neuropsychiatry, Psychiatry, and Lifestyle Medicine — calls herself a "radical behaviorist." Like other practitioners of cognitive behavioral therapy (CBT), she sees the troublesome thoughts and emotional states of many psychiatric disorders as just another form of behavior, which can be reshaped through self awareness and practice — much like you might work at avoiding junk food or not biting your nails.Of course, one of the biggest challenges is the practice part. It's no easy task for patients to practice experiencing the world in a more positive, healthy way. This is why Bullock is eager for practitioners of CBT and related forms of psychotherapy to embrace virtual reality technologies — which enable psychiatrists to prescribe precisely calibrated "experiences" to treat cognitive & behavioral disorders.We started by discussing early results from a clinical trial for a virtual reality-enhanced intervention major depressive disorder, which Dr. Bullock recently launched with support from the Wu Tsai Neurosciences Institute Neuroscience:Translate program. Join us to learn more about how VR is transforming the world of psychotherapy!Learn MoreImagining virtual reality as a simple tool to treat depression  (Stanford Medicine, 2024)Extended Reality(XR) enhanced behavioral activation for treatment of Major Depressive Disorder (2022 Neuroscience:Translate grant)Clinical Trial: Virtual Reality Behavioral Activation: An Intervention for Major Depressive DisorderThe Stanford Virtual Reality and Immersive Technologies (VR-IT) ProgramRecent VR-IT publicationsEpisode CreditsThis episode was produced by Michael Osborne, with production assistance by Morgan Honaker, and hosted by Nicholas Weiler. Art by Aimee Garza.Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

In this episode Dr. Lyon sits down with Dr. Erik Won, President and Chief Medical Officer of WAVE Neuroscience Biotechnology. Dr. Won shares his journey from being a Navy flight surgeon to leading groundbreaking research in brain health. If you struggle with brain fog, depression, PTSD, or traumatic brain injury, this episode is for you. Learn about innovative treatments that are changing lives and providing hope for those suffering from brain-related conditions. Don't miss this enlightening conversation on the future of neuroscience!Dr. Erik Won is President and Chief Medical Officer of Wave Neuroscience, Inc; a biotechnology company that has innovated breakthrough technologies called Magnetic e-Resonance Therapy (MeRT) and Synchronized Transcranial Magnetic Stimulation (sTMS). These technologies utilize computational neuroanalytics and brain imaging to customize treatment protocols with the aim of restoring optimal neurological function. These modalities represent a form of precision-guided medicine that has been researched or is currently being used by premier institutions such as US Special Operations Command, Stanford University School of Medicine, Duke University - Human Performance Opti-Lab, University of Southern California (USC) Center for Neurorestoration, the University of California Los Angeles (UCLA) - David Geffen School of Medicine, University of Pennsylvania, Brown University, and the Texas A&M Institute for Bioscience and Technology, among others. Erik joined Wave Neuroscience after serving as the Chief Physician and Chief Technology Officer (Health Services) for the Boeing Company. He also served as a US Navy Flight Surgeon for Marine Medium Helicopter Squadron 268, and received the distinction of serving as the ACE Flight Surgeon for the 11th Marine Expeditionary Unit, 1st Marine Expeditionary Force. Dr. Won has been published in numerous peer-reviewed journals, textbooks, and presented in numerous academic conferences. He completed his residency at the Harvard OEM combined residency program and was appointed Chief Resident. He received a Masters in Public Health (MPH) from the Harvard School of Public Health and Masters in Business Administrations (MBA) from the University of Southern California, Marshall School of Business.

Special guest Marshall E. Cates, PharmD, BCPP, FASHP, FCCP, FALSHP, Professor of Pharmacy Practice from the McWhorter School of Pharmacy at Samford University joins us to talk about pharmacotherapy for anxiety and depression.Listen in as we discuss pharmacotherapy for managing generalized anxiety disorder and major depression, with a focus on tailoring first- or second-line options to individual patient needs.You'll also hear practical advice from Craig D. Williams, PharmD, FNLA, BCPS, a member of TRC's Editorial Advisory Board and Clinical Professor of Pharmacy Practice at the Oregon Health and Science University.For the purposes of disclosure, Dr. Cates reports relevant financial relationships [psychiatry] with Biogen, Sage Therapeutics (honorarium); Otsuka (speakers bureau).The other speakers have nothing to disclose.  All relevant financial relationships have been mitigated.TRC Healthcare offers CE credit for this podcast. Log in to your Pharmacist's Letter or Prescriber Insights account and look for the title of this podcast in the list of available CE courses.The clinical resources mentioned during the podcast are part of a subscription to Pharmacist's Letter and Prescriber Insights: Chart: Pharmacotherapy of Anxiety Disorders in AdultsChart: Choosing and Switching AntidepressantsChart: Combining and Augmenting AntidepressantsIf you're not yet a Pharmacist's Letter or Prescriber Insights subscriber, find out more about our product offerings at trchealthcare.com. Follow or subscribe, rate, and review this show in your favorite podcast app. Find the show on YouTube by searching for ‘TRC Healthcare' or clicking here. You can also reach out to provide feedback or make suggestions by emailing us at ContactUs@trchealthcare.com.

What do you do when you find yourself on 14 prescription medications and your health is only declining? On this episode of Vitality Radio, Jared interviews Suzanne Bates, one of our own at Vitality Nutrition. She shares her story of taking her health into her own hands when western medicine failed her. Suzanne was an ICU nurse and believed wholeheartedly in the ways of western medicine, until she realized it wasn't helping her at all. You'll hear how she went from almost bedridden with multiple diagnoses and drugs for all of them, to vibrant and healthy, no longer burdened with those illnesses, and down to one prescription which is on its way out. She shares the incredible story of how she was led to Vitality Nutrition and the one supplement that started her on a journey to natural healing and a life full of hope and joy.Products:N.O. Cardio BoostSunChlorella ChlorophyllBerberineAlpha Lipoic AcidSuntheanineTri-IodineRhodiolaAdditional Information:#264: Emotional Vitality: Jen's Story Part 1 - From Addiction and Mental Illness to VitalityVisit the podcast website here: VitalityRadio.comYou can follow @vitalityradio and @vitalitynutritionbountiful on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Please also join us on the Dearly Discarded Podcast with Jared St. Clair.Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.

There's a new pilot project aimed at improving the lives of New Brunswickers with major depressive disorder. Dr. David Elias thinks this treatment could be a gamechanger because depression costs so much in health care, lost time and productivity.

Today I explore fascinating research which compares the effectiveness of probiotic supplementation versus anti-depressant medication for depression. The results may surprise you.See omnystudio.com/listener for privacy information.

Jennifer Ginty is a single mom and entrepreneur who lives with Complex PTSD and Major Depressive Disorder from childhood trauma. Throughout her life, Jen has learned valuable coping skills and has made it her mission to help others to better understand their own emotions. Jen has faced obstacles in her healing journey - from becoming a mother without a healthy parental model of her own to overcoming her inner saboteur while coping with the symptoms of CPTSD and Depression. She has spent the last 4 years developing My Moody Monster - a pull apart plush toy that has helped children to get out their frustrations in a safe way and giving families a tool to  talk about emotions and communication. Jen believes by sharing her own story she can help others to know they are not alone.  Her YouTube channel features her Moody Talks focusing on an emotion each month and teaching coping skills that have helped her with her own mental health. Find out more on Healthy Habits with Dori DeCarlo. Connect with Jennifer at MyMoodyMonster.com and follow on Instagram, Facebook, YouTube and LinkedIn. Please support UnsilencedVoices.org and their mission. We thank Smith Sisters and the Sunday Drivers for our theme song, "She is You". WordofMomRadio.com - sharing the wisdom of women, in business and in life.  

The journey of healing is a personal odyssey, unique and transformative for every individual who embarks upon it. For Jen Ginty, her odyssey led her to create "My Moody Monster," a pull apart plush toy designed to assist children and adults alike in managing their complex emotional landscapes. The podcast episode featuring Jen's story offers a profound look into the heart of emotional wellness, a subject that resonates with countless individuals navigating their own challenges with mental health.Jen is a single mom and entrepreneur who lives with Complex PTSD and Major Depressive Disorder from childhood trauma. Throughout her life, Jen has learned valuable coping skills and has made it her mission to help others to better understand their own emotions. Jen has faced obstacles in her healing journey - from becoming a mother without a healthy parental model of her own to overcoming her inner saboteur while coping with the symptoms of CPTSD and Depression.  She has spent the last 4 years developing My Moody Monster - a pull apart plush toy that has helped children to get out their frustrations in a safe way and giving families a tool to talk about emotions and communication. Jen believes by sharing her own story she can help others to know they are not alone. Her YouTube channel features her Moody Talks focusing on an emotion each month and teaching coping skills that have helped her with her own mental health.Connect with Jen on:YoutubeFacebookInstagramLinkedInand her website http://www.mymoodymonster.comI am your host Carol Clegg. As a coach, I help women in business explore fresh ways to focus on their projects, find the right tools for accountability and learn how to build a positive mindset which in turn allows for more empathy, for self and others.With my personalized accountability and progress coaching combined with the powerful Positive Intelligence program, you'll find ways to shift into an overall happy space. If you would like to take the complimentary Saboteur assessment, I offer a complimentary coaching session to explore your results. Take your assessment here or visit carolclegg.com BOOK your ✅ 30 minute complimentary exploration call HERE Connect on LinkedIn and Instagram or join my Facebook group "Mindset, Tips & Tools for Women in Business"

Ask Kati Anything, your mental health podcast episode 217 | This week licensed therapist Kati Morton talks about getting past inner resistance in therapy, how to keep going when we feel like giving up, and what a therapist would do if their client is intellectualizing everything. She then explains what a body memory is and why our trauma memories can be so spotty. Finally, she discusses anxiety about making phone calls, and why we can be so worried about every little thing we do, and believe that people are going to think we are weird. Audience questions: 1. Could you possibly talk about getting past inner resistance in therapy? I've been in therapy for about 8 months and feel like we've done some amazing work, but have noticed I'm hitting some type of wall within myself that I'm not sure how to get past. It's like I've kind of traveled through all the issues I've been conscious of, but now that we're deeper in I'm realizing there's a lot going on that I was not aware of... 01:14 2. Hi Kati. How do I keep going? I feel like giving up. I have Major Depressive Disorder. Suicidal thoughts and self injury consume me. I've done talk therapy, CBT, DBT, ACT, TMS, and ECT. Nothing has helped. I've been hospitalized twice. I've been on so many medications I can't keep track anymore. I feel so alone in this. I do have a psychiatrist, therapist and loving family but they don't understand... 09:54 3. I was wondering how a therapist would approach working with a client who intellectualizes everything? I find CBT and DBT unhelpful because everything my therapist is saying, while totally true, I've already known about and pieced together myself. I think that's also where I get so stuck with therapy- I KNOW there are these pieces out of place that aren't serving me. I KNOW why I am the way I am, but I don't know what to do about it? 24:54 4. I saw one of your older videos about people not remembering their trauma or remembering it in patches but I'm the opposite, I remember what happened to me in great detail even down to what I was wearing, what they were wearing the day and time everything. The only problem I do have is deciding if what actually happened to me was SA... 33:17 5. I noticed recently that I'm really scared to call people I haven't spoken to in a long time. I know they'd love to hear from me and vice versa if they called me. So what's the hang-up (pun intended)? How do I reduce my anxiety around it? It's just literally a fear of pressing call and waiting while the phone rings. I'm not actually scared to talk to these people. What's that about? How do I make pressing the button or the waiting time while the phone rings before they pick up easier? How do I select who to call? Are there steps I can take to get to that point? 42:46 6. Hey Kati what is it called when you are so concerned with the way you walk, blink , eat, move your mouth when you talk, ect. I feel like I walk weird, and I talk weird. I feel like I'm insecure about my voice being too deep or my laugh being too loud. Just little everyday things. I never hear about this. 46:26 PUBLISHED BOOKS ⁠⁠⁠⁠⁠⁠Traumatized⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠Are u ok?⁠⁠⁠⁠⁠⁠ A great way to support my channel is to visit our sponsors by using these links: ⁠⁠⁠⁠⁠⁠Amazon⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠Instacart⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠ONLINE THERAPY⁠⁠⁠⁠⁠⁠ While I do not currently offer online therapy, BetterHelp can connect you with a licensed, online therapist: ⁠⁠⁠⁠⁠⁠https://betterhelp.com/kati⁠⁠⁠⁠⁠⁠ (enjoy 10% off your first month) SOCIAL ⁠⁠⁠⁠⁠⁠X⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠TikTok⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠Facebook⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠Pinterest⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠Patreon⁠⁠⁠⁠⁠⁠ PARTNERSHIPS Linnea Toney linnea@underscoretalent.com --- Send in a voice message: https://podcasters.spotify.com/pod/show/askkatianything/message Support this podcast: https://podcasters.spotify.com/pod/show/askkatianything/support

Big Feelings With Jennifer Ginty Blossom Your Awesome Podcast Jennifer Ginty joins us for episode #277 of the Blossom Your Awesome Podcast.  Jennifer is a Mental Health Advocate and the founder of My Moody Monster, a pull apart toy for kids to help them better cope when those BIG feelings come up. Jennifer is a single mother and survivor of childhood trauma living with Complex PTSD and Major Depressive Disorder. Throughout her healing journey, Jennifer has learned many coping skills to help through the difficult symptoms of her Mental Health Diagnoses. During a particularly hard period, Jennifer created My Moody Monster, a pull apart plush doll, to help children to better cope with their own frustrations in a safe way. Families, therapists and teachers have found Moody to help with communicating with children about their emotions and helping them understand that all feelings are valid.To learn more about Jennifer check out her YouTube channel here. To follow me, get bonus content from the show and to support my writing Check me out here at my Substack. To see more of my work check me out at my website. Or my other site

TAKEAWAYSAlternative wellness and the use of psychedelic medicine for mental health treatmentPersonal journey and founding of Nushama, a legal psychedelic therapy clinic in New York CityProcess and benefits of ketamine treatment for conditions such as depression and PTSDHistory and potential of psychedelic medicine in the context of mental health and wellnessReasons behind the historical suppression of psychedelic medicineTherapeutic process at Nushama and the importance of mindset and settingResults of a study demonstrating the reduction in PTSD symptoms among participants who underwent ketamine treatmentImpact of psychedelic therapy on addressing the mental health crisis and the need for alternative solutions to traditional psychiatric medicationsFuture plans for Nushama and its growth, including the potential use of psilocybin, MDMA, and LSD in treating various psychiatric indicationsInvitation to visit Nushama in New York for treatment and where to learn more about the clinic and psychedelic medicineTIMESTAMPSIntroduction (00:00:00) Introduction to the Vibe Science podcast, focusing on holistic wellness and alternative wellness approaches.Discussion on Alternative Wellness (00:01:17) The hosts talk about the importance of holistic wellness and the shift from alternative to mainstream wellness practices.Jay Godfrey's Journey (00:03:28) Jay Godfrey shares his personal journey, including his career shift from fashion to psychedelic therapy, and his experience with talk therapy.Psychedelic Medicine's Potential (00:02:43) The potential of psychedelic medicine in mental health treatment is discussed, including its history and future prospects.Psychedelic Medicine's History (00:10:43) The historical and political reasons behind the restriction of psychedelic medicines are explained, including the impact of the drug war and government policies.Psychedelic Medicine's Benefits (00:15:45) The process and benefits of ketamine treatment at Nushama are described, including the medical intake, treatment protocol, and therapeutic experiences.Results of Ketamine Treatment (00:22:13) The positive outcomes of ketamine treatment for PTSD are highlighted, including the reduction and elimination of diagnoses.Importance of Mental Health Treatment (00:23:32) The importance of making mental health treatment, including psychedelic therapy, a standard of care and accessible to those in need is emphasized.Ketamine Therapy (00:25:39) Discussion on the impact and personal experiences of ketamine therapy for mental health treatment.Mental Health Statistics (00:28:55) Exploration of the alarming mental health statistics in the United States, including the prevalence of depression and its impact on physical health.Psychedelic Medicine Future (00:32:19) Jay Godfrey discusses the future plans and ambitions of Nushama, envisioning a multi-site psychedelic wellness center with various treatment modalities.Nushama Information (00:34:09) Information about Nushama and psychedelics can be found on their website, Instagram, and YouTube, as well as the exciting future of alternative mental health treatment. Follow us on Instagram: @Vibe.Science Subscribe to our YouTube Page: www.youtube.com/@Vibe.Science

African Americans have the highest rates of Post Traumatic Stress Disorder (PTSD) and Major Depressive Disorder compared to any other racial group. Candice Cox, Therapist and Founder of KHAOS, Inc. (Keep Healing and Overcoming Struggles), joins Carol to discuss how we got here and what needs to be done to overcome trauma and ensure mental well-being. To experience more of the #CarolDanielPodcast, visit ninepbs.org/listenstlouis. Subscribe to #NinePBS so you never miss a podcast episode! https://bit.ly/3OIXoWD.

A huge problem with current psychiatric diagnosis is that it often lumps completely unrelated things under the same vast and vague tent, such as with the diagnosis of "Major Depressive Disorder".   Here Craig sits down with his patient Rebecca to try to make sense of her complex early onset depression and how it played out via addiction, anorexia, and pathological caretaking and how she was finally able find the grace and compassion to prioritize care for herself.Bringing Therapy into Med Management-- An intensive psychotherapy training in Colorado with Dr.  Hhttps://www.craigheacockmd.com/training/BFTA on IG @backfromtheabysspodcasthttps://www.instagram.com/backfromtheabysspodcast/BFTA/ Dr. Hhttps://www.craigheacockmd.com/podcast-page/

In a shocking case of senseless violence, 19-year-old Brian Cohee II brutally murders and dismembers a homeless man, Warren Barnes, in Grand Junction, Colorado, leaving the community questioning the killer's sanity and motive as disturbing details of his past and the gruesome crime come to light during a high-profile trial. Subscribe on your favorite podcasting apps: https://talkmurder.com/subscribeSupport us on patreon: https://patreon.com/talkmurderSee our technology: https://talkmurder.com/gearContent warning: the true crime stories discussed on this podcast can involve graphic and disturbing subject matter. Listener discretion is strongly advised.Fair use disclaimer: some materials used in this work are included under the fair use doctrine for educational purposes. Any copyrighted materials are owned by their respective copyright holders. Questions regarding use of copyrighted materials may be directed to legal [@] Talkocast.com

Hey Friends~  As we continue Guest Episode Month here at the Language of play,  Today's guest shares a tangible way your child can work through their Big Emotions!  And, as you help them, you find you will help yourself with your lingering junk of the past!  Helping your child is a great way to grow together.  Today, Jennifer Ginty will share how to do it with a doll.  Remember, There is never a wrong time to start a healing journey.  And, Healing is never linear. Jennifer has generously offered a 15% discount if you use the code PLAY at checkout for her doll!   Always cheering you on!  Dinalynn   CONTACT the Host, Dinalynn:  hello@thelanguageofplay.com   ABOUT THE GUEST:     Jennifer is a single mom and entrepreneur who lives with Complex PTSD and Major Depressive Disorder from childhood trauma. Throughout her life, Jen has learned valuable coping skills and has made it her mission to help others to better understand their own emotions. Jen has faced obstacles in her healing journey - from becoming a mother without a healthy parental model of her own to overcoming her inner saboteur while coping with the symptoms of CPTSD and Depression. She has spent the last 4 years developing My Moody Monster - a pull apart plush toy that has helped children to get out their frustrations in a safe way and giving families a tool to talk about emotions and communication. Jen believes by sharing her own story she can help others to know they are not alone. Her YouTube channel features her Moody Talks focusing on an emotion each month and teaching coping skills that have helped her with her own mental health. CONTACT THE GUEST:   jen@mymoodymonster.com  Website: http://www.mymoodymonster.com For 15% off, use the code PLAY at checkout when you purchase Moody! YouTube: http://www.youtube.com/@mymoodymonster Instagram: http://www.instagram.com/mymoodymonster Facebook: http://www.facebook.com/my-moody-monster TikTok: http://www.tiktok.com/@mymoodymonster Threads: http://www threads.net/@mymoodymonster   RESOURCES from The Language Of Play Sign up for my newsletter! Newsletter Opt-in Sign up for FREE 21 Days of Encouragement in your inbox! Encouragement Sign-up Join my new FREE Facebook Community HERE! Sign up for a 15 min "Let's Meet Session" on zoom!  Let's Meet Session For Speaking Engagements or For 1:1 or Group Parent Coaching (virtual or live), contact me at hello@thelanguageofplay.com   If You Liked This Episode, You Will Want To Listen To These Episodes: 33 Series: “Why Won't the Kids Listen!?” part 6: BiG EMoTioNS! 4 things to ask yourself before you respond 41 Can You Hear What Your Child Is NOT Saying? 4 Strategies to Help Young Kids With BIG Adjustments 47 EXPERT: Jaci Finneman: Helping Kids Make Apology with the “Make It Right” Technique 69 Can You Really Reparent Yourself? And When You Should Consider It. 72 Do You Give a Good Examples Of Managing Your Own Voices? 4 Strategies to Manage Being Disappointment with Yourself 73 What Is The Motive Behind Your Child's Behavior? It May Not Be As It Seems. 90 What Does Improv Have To Do With Parenting?  EVERYTHING!!  

Today, you'll learn about the surprising effect our immune system has on our emotional health, a new discovery about the biological clock of plants, and how researchers are rediscovering the science of psychedelics. Stress & Immunity “Mount Sinai Study Shows That Circulating Immune Cells Drawn to the Brain During Stress Can Control Emotional Behaviors.” Mt. Sinai. 2024. “Major Depressive Disorder.” by Navneet Bains & Sara Abdijadid. 2023. “Circulating myeloid-derived MMP8 in stress susceptibility and depression.” by Flurin Cathomas, et al. 2024. Crop Resilience “USC researchers uncover biological circuit that protects plants from extreme conditions.” EurekAlert! 2024. “Climate Change Impacts on Agriculture and Food Supply.” EPA. 2023. “The interplay between the circadian clock and abiotic stress responses mediated by ABF3 and CCA1/LHY.” by Tong Liang, et al. 2024. Psychedelic Scale “An intriguing psychedelic assessment is back from the dead, thanks to Swiss scientists.” by Eric W. Dolan. 2024. “The Psychedelic Integration Scales: Tools for Measuring Psychedelic Integration Behaviors and Experiences.” by Tomas Frymann, et al. 2022. “The revival of the psychedelic experience scale: Revealing its extended-mystical, visual, and distressing experiential spectrum with LSD and psilocybin studies.” by Kurt Stocker, et al. 2023. Follow Curiosity Daily on your favorite podcast app to get smarter with Calli and Nate — for free! Still curious? Get exclusive science shows, nature documentaries, and more real-life entertainment on discovery+! Go to https://discoveryplus.com/curiosity to start your 7-day free trial. discovery+ is currently only available for US subscribers. Hosted on Acast. See acast.com/privacy for more information.

SobahSistahs Empowerment Club In this episode I chat with Ginger Robinson, known to her followers as Mrs. Robinson. Ginger is a 53-year-old online content creator and media personality from Pittsburgh, Pennsylvania. She has been sober since 2003, after many MANY attempts to stop drinking. A suburban mom of 2 older kids, a son who's 18 and a 28-year-old daughter, Ginger feels as if she's lived multiple lifetimes, categorized by pain and struggle to live a content, serene life while also battling Major Depressive Disorder and crippling anxiety, all while maintaining her sobriety over the years. Growing up as an only child, she learned to be independent at a very early age, and while navigating life, there was a constant conflict of being an overachiever and feeling “less than.”   Ginger graduated from college in the early 90s, got her Masters Degree, and worked as a teacher in her early 20s. She moved around a little (San Diego, Ocean City, Boca Raton, Philly, New Canaan, CT, and Pittsburgh) before actually getting her shit together in 2003. Marriage, having kids, and getting sober changed her career trajectory, and she began working in advertising selling tiny newspaper ads (yes it was that long ago that people were still reading newspapers). She became dedicated to the industry and worked her ass off climbing the corporate career ladder, eventually being recruited by one of the first Fortune 500 tech dot coms. Working in the true Don Draper Mad Men world, she had a very successful career as a well-respected senior software exec in the ad industry, specializing in helping large companies with their digital programmatic advertising,  data analytics, and social branding strategies.  Just before her 50th birthday (and at the start of COVID), she switched gears into content creation and the adult industry and Mrs. Robinson was born (shout out to 1967's The Graduate). The goal then (and still is) to continue to try to break the glass ceiling on what older women can and cannot do according to societal attempts to convince us that “younger is better” in the world of beauty, fashion, brains, and sex.  Sobriety and recovery help tremendously and have been the foundation of her life both professionally and personally. I hope you enjoy this episode as much as I did. Follow Mrs. Robinson on Instagram Follow Mrs. Robinson on TikTok SobahSistahs Vermont Retreat SobahSistahs on Instagram --- Send in a voice message: https://podcasters.spotify.com/pod/show/sobahsistahs/message

What is depression? Neil deGrasse Tyson and co-hosts Chuck Nice and Gary O'Reilly break down the neuroscience behind major depression, its treatments, and the factors that contribute to this pervasive condition with neuroscientist Heather Berlin, PhD.NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here: https://startalkmedia.com/show/why-we-get-depressed-with-heather-berlin/Thanks to our Patrons Geoff Malone, Neander Rowlett, Brial Teel, Baran Blaser, Maxwell Miller, Doug Litwin, and Edward Bally for supporting us this week.

Avi's journey is one of personal transformation and resilience. Despite facing challenges and struggling with feelings of worthlessness and inadequacy in his early life, Avi has emerged as a licensed realtor, professional salesperson, best-selling author, and three-time ax-throwing champion. His background includes a love for sports such as football, ultimate frisbee, and ping-pong, as well as an interest in video games, documentaries, and solving the Rubik's cube. Growing up in an environment that was not conducive to his well-being, Avi faced academic struggles and was later diagnosed with Bipolar Type I and Major Depressive Disorder as a young adult. Despite joining the US National Guard to escape feelings of shame and contribute to his country, Avi found himself still grappling with personal challenges, including issues related to substance abuse and a sense of being at rock bottom. However, his journey took a turn when he embraced his role as a self-starter, independent learner, and resilient survivor. Avi used his experiences and rejection as fuel for personal growth, eventually channeling his energy into writing. What started as documenting his childhood experiences transformed into thirty titles, showcasing his evolution into life coaching. Today, Avi is a public speaker who aims to inspire others, particularly those struggling with business, life, and mental health. His mission is to help individuals discover the champion within themselves, emphasizing that true success is not about winning for personal gain but about empowering others to achieve their potential.   Find Avi at www.aviwolfson.com www.linkedin.com/in/aviwolfson  

Hello friends! In today's in-depth episode, we embark on a comprehensive exploration of depression, a condition that's far more complex than the occasional sadness or the transient moods we all experience. Our journey aims to shed light on the multifaceted nature of depression, affecting individuals across the globe in myriad ways. We delve into the clinical aspects, the personal stories, and the common misconceptions surrounding this pervasive mental health condition. We start by breaking down the very concept of depression, moving beyond the simple definition to uncover its roots and how it impacts the human experience. Through the lens of the DSM-5, we explore the criteria for diagnosing Major Depressive Disorder, highlighting the diversity of symptoms and the profound effect they have on individuals' lives. Our discussion takes a personal turn as we examine the experiences of James and Ellie, two hypothetical cases that illustrate the varied manifestations of depression. James, with his outward success masking an internal struggle, and Ellie, facing overt challenges in her transition to college life, offer insights into the silent battles many face. Addressing common misconceptions, we challenge the stigmas associated with depression, emphasizing its complexity and the fact that it's not a sign of weakness, nor is it something one can simply "snap out of." We also touch upon the idea that depression can affect anyone, regardless of how "good" their life may seem. As we move towards solutions, we discuss the treatability of depression, underscoring the effectiveness of medication, therapy, and lifestyle changes. We emphasize that for those facing this condition, there is hope, and a multitude of resources available to support their journey towards recovery. In closing, we reaffirm the importance of understanding, empathy, and support in the battle against depression. We encourage our listeners to reach out for help, to engage in conversations about mental health, and to seek the resources necessary to navigate this challenging yet treatable condition. As always, you can send me questions to duffthepsych@gmail.com and find the full show notes for this episode, including links to resources and further reading, at http://duffthepsych.com/episode384. ---- Sponsored by BetterHelp: In my journey to enhance my relationships, I've found therapy invaluable for navigating the complexities of connections with others. BetterHelp offers online therapy that's tailored to your needs, allowing you to work through relationship challenges with a licensed therapist from the comfort of your home. Start your journey towards healthier relationships and get 10% off your first month at betterhelp.com/duff. Sponsored by Chomps: If you're like me and snacking is your Achilles' heel, Chomps is the game-changer you need. Their meat sticks are not only a healthier snacking alternative but are also packed with protein and come in delicious flavors like taco, made from high-quality, sustainably sourced meat. Take advantage of 20% off your first order plus free shipping by visiting chomps.com/duff.

This week's guest is deeply passionate about parenting, mental health, and wellness,  They grew up with the impression they were losers, feeling worthless and helpless. The environment they rose from wasn't healthy and they struggled academically, and while resilient, they felt inadequate for a long time. Avi Wolfson was as a young adult, diagnosed with Bipolar Type I (previously known as Manic Depression) and Major Depressive Disorder (MDD). Anxiety was evident and present within his family but seldom talked about, nor did he have permission to feel sad or express any feeling besides happiness. In addition, he felt pressured to take on heavily religious activities but had no interest in them; this all took a heavy toll, leading him to drink, take drugs, and music as vices. Avi joined the US National Guard in high school to absolve himself of this shame. he was proud to serve a country that he loved and protect the society in which we live so freely, but being in the military didn't prevent any of those problems, nor did it make them go away. and he was back at square one and rock bottom. Avi has struggled with MDD, Bipolar I, and has gone through very dark times in a traumatic childhood as a young, separated father to a girl, they believe their experience and unique perspective on single parenting would be valuable as he has become a stronger and more resilient person by finding light within my darkness. Find Avi here www.aviwolfson.com www.linkedin.com/in/aviwolfson

Today, Ali and Asif discuss comedian Ricky Gervais. They discuss his early life, including his stint in a New Wave Band in the early 1980's. They then discuss the groundbreaking success of ‘The Office' and some of his subsequent shows including ‘Extras' and ‘After Life'. They pivot to then discussing his stand up comedy, including his hosting of the Golden Globes (and comparing him to recent host Joy Koy). After a digression about Gervais' podcast, they guys talk about his Netflix comedy specials, including the controversy surrounding his most recent special “Armageddon'.    Gervais' show ‘After Life' was about a man battling depression, so in the second half, Ali asks Asif about this disorder. Asif talks about how common it is, and what we think causes it. He then goes over the symptoms of depression and how “Major Depressive Disorder” is diagnosed. He goes over the relationship of depression and suicide and the prognosis of depression. Asif then goes over the treatment of depression (not with dogs), with both medication and therapy. He then briefly touches on electroconvulsive therapy (ECT) for depression.  The opinions expressed are those of the hosts, and do not reflect those of any other organizations. This podcast and website represents the opinions of the hosts. The content here should not be taken as medical advice. The content here is for entertainment and informational purposes only, and because each person is so unique, please consult your healthcare professional for any medical questions.   Music courtesy of Wataboi and 8er41 from Pixabay   Contact us at doctorvcomedian@gmail.com   Follow us on Social media: Twitter: @doctorvcomedian Instagram: doctorvcomedian   Show Notes: Seona Dancing - Bitter Heart HD Full Video: https://www.youtube.com/watch?v=UDvYpOnN9Qk Seona Dancing - More To Lose (Razzmatazz, 07/06/83): https://www.youtube.com/watch?v=ABjYSxyUD98 Ricky Gervais - Golden Years (David Bowie homage): https://www.youtube.com/watch?v=_uQ019iAcQM&t=350s Ricky Gervais – Golden Globes 2020: https://www.youtube.com/watch?v=iJOb9xHggS4 Willow: Behind The Magic Trailer | Disney+: https://www.youtube.com/watch?v=I_l4qI0nXz8 Depression: https://emedicine.medscape.com/article/286759-overview#a4

Interview with Nils R. Winter, MSc, author of A Systematic Evaluation of Machine Learning–Based Biomarkers for Major Depressive Disorder. Hosted by John Torous, MD, MBI. Related Content: A Systematic Evaluation of Machine Learning–Based Biomarkers for Major Depressive Disorder

Join Kiah Penfield as she takes us through her compelling narrative of living with mental illness, her educational pursuits as a deaf educator, and her mission to shed light on unsolved crimes. Her candid discussion on mental health treatments and the power of songwriting as an emotional outlet will leave you enlightened and encouraged to seek your own paths of healing and expression.

Transcranial magnetic stimulation (TMS) represents an exciting non-medication and noninvasive option for treatment of some brain health conditions, specifically TMS for depression. TMS works by using magnetic therapy in the form of magnetic field pulses to stimulate the brain's nerve cells to alleviate the symptoms associated with depression. In addition, there is growing research exploring the effectiveness of TMS in other neurological conditions, including Alzheimer's disease and other memory disorders.At Pacific Brain Health Center, Dr. David Merrill offers TMS for depression using a MagVenture device. It offers a unique, short, 3 minute TBS (theta burst) protocol for the treatment of Major Depressive Disorder in adult patients who have failed to receive satisfactory improvements from prior antidepressant medication in the current episode.

Dr. Peter Bongiorno discusses An Integrative Approach to Depression and Anxiety at the Functional Medicine Discussion Group meeting on September 28, 2023 with moderator Dr. Weitz.   [If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.]    Podcast Highlights 9:27   The Neurotransmitter Theory of Depression and Anxiety.  This theory is that specific neurotransmitters are responsible for mood disorders. For example, this theory includes the idea that depression is caused by a deficiency of serotonin.  In 2008 the New England Journal of Medicine published a paper suggesting that maybe this whole serotonin theory wasn't true, and a lot more people who took SSRIs actually didn't have as positive effect. [Belmaker RH, Agam G. Major Depressive Disorder. N Engl J Med 2008; 358:55-68.]  Then Fournier in JAMA published a paper showing that SSRIs had no better effect than placebo for mild to moderate depression, though they are beneficial for severe depression. In 2020 a paper discussed that the evidence is that "The main areas of serotonin research provide no consistent evidence of there being an association between serotonin and depression, and no support for the hypothesis that depression is caused by lowered serotonin activity or concentrations." [Moncrieff, J., Cooper, R.E., Stockmann, T. et al. The serotonin theory of depression: a systematic umbrella review of the evidence. Mol Psychiatry (2022).]  Some studies show that a medication, Stablon, which lowers serotonin, is equally effective as SSRI drugs that raise serotonin levels.  This is not to say that serotonin has no effect but only 27 to 35% of patients who take an antidepressant have a positive response.  Even if serotonin is a factor, there may be other factors that affect whether that antidepressant can be effective, such as do they have enough amino acids in their diet to make neurotransmitters?  It could also be because estrogen or other hormones are low or their adrenals or thyroid are off. Even if depression or anxiety are related to a neurotransmitter issue, we should be trying to figure out what caused this dysregulation of neurotransmitters.  Those reasons can include physiology, nutrients, hormones, inflammation, digestion, lack of sleep, not enough exercise, too much exercise, mitochondrial dysfunction, toxicity, mold. 16:02  SSRIs.  Drugs that potentially modulate serotonin and the other neurotransmitters, like the Selective Serotonin Reuptake Inhibitors (SSRI) even when they do work, tend to stop working after a period of time. And there are many problems with these drugs, including that they are very difficult to get off of these drugs when you want to stop taking them and they have significant side effects, including a significant increase in all-cause mortality.  Dr. John Neustadt spoke at the Connecticut Naturopathic Conference about how SSRIs increase the risk of osteoporosis by changing osteoblastic and osteoclastic activity.  Also when you place someone on these SSRI medications, it does change the function of the HPA axis and does change the ability and the balance of how the body regulates things like circadian rhythm, how it regulates the production of neurotransmitters, how it regulates the production of receptors. 20:32  Dietary Factors.  Two of the most important factors are the patient sleeping and pooping?  It is critical that the patient is having a good bowel movement daily.  We need to facilitate that whether it is adding fiber, water, magnesium, etc. If the patient has a lot of anxiety, that tends to put them into sympathetic mode, which shuts down the bowels. So we need to calm their anxiety, whether that is through supplements or acupuncture. Then the next step is to look at their diet and see what we can change to get them eating better.