Saving Minds

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Dr. Elliot Goldstein and Shanti Skiffington discuss the future of medicine for Alzheimer’s and Parkinson’s diseases.

ProMIS Neurosciences

  • Nov 2, 2020 LATEST EPISODE
  • monthly NEW EPISODES
  • 16m AVG DURATION
  • 32 EPISODES


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Latest episodes from Saving Minds

Episode 31 – Audio white paper: Perspective on Aducanumab’s Nov. 6 Advisory Committee

Play Episode Listen Later Nov 2, 2020 21:53


This episode is a recording of the White Paper: Perspective on Aducanumab’s Nov. 6 Advisory Committee, read by Shanti Skiffington.

Episode 30 – Dr. Scott Napper on an Alzheimer’s Vaccine

Play Episode Listen Later Oct 27, 2020 12:00


This week Shanti and Eliot talk to Dr. Scott Napper, Professor of Biochemistry, Microbiology & Immunology at the University of Saskatchewan, about the future of an Alzheimer’s Vaccine.

Episode 29 – Detecting, treating, and preventing Alzheimer’s disease: Dr. Neil Cashman explains

Play Episode Listen Later Oct 9, 2020 8:54


On today's episode, Shanti and Eliot talk to Dr. Neil Cashman about a vaccine for Alzheimer’s disease and how that fits into the detection, treatment, and prevention of the disease.

Episode 28 – Dr. Josè Luis Molinuevo of the BarcelonaBeta Brain Research Center on his biomarker presentation at AAIC

Play Episode Listen Later Sep 9, 2020 12:40


Shanti and Eliot talk to Dr. Josè Luis Molinuevo of the BarcelonaBeta Brain Research Center about his experience at AAIC, and the presentation he gave on biomarkers.

Episode 27 – Using Artificial Intelligence to speed Alzheimer’s studies

Play Episode Listen Later Jul 30, 2020 24:42


This week, Shanti and Eliot talk to founder and CEO of Unlearn, Charles Fisher. They discuss how artificial intelligence can effect Alzheimer's drug research.

Episode 26 – A diagnostic test for Alzheimer’s disease

Play Episode Listen Later Jul 9, 2020 17:18


Episode Notes Shanti and Elliot talk to Dr. James Kupiec about a diagnostics test for Alzheimer's disease.

Episode 25 – Trusting Covid-19 antibody testing—the CDC weighs in

Play Episode Listen Later Jun 17, 2020 18:15


Episode Notes Shanti and Elliot discuss recent developments in antibody testing for Covid-19

Episode 24 – New Ways to Attack ALS and Other Protein Misfolding Diseases with Johanne Kaplan

Play Episode Listen Later May 21, 2020 10:45


Elliot and Shanti talk to Johanne Kaplan about a new way to attack ALS and other protein misfolding diseases,

Episode 23 – Introducing Intrabodies with Dr. Johanne Kaplan.

Play Episode Listen Later Apr 30, 2020 12:00


This week Shanti and Elliot discuss Intrabodies with Dr. Johanne Kaplan

Episode 22 – Worried about aducanumab? Don’t be. Dr. Jim Kupiec explains

Play Episode Listen Later Apr 24, 2020 12:41


Dr. Jim Kupiec explains why there is nothing to worry about regarding the recent news about aducanumab.

Episode 21 – “For a COVID-19 antibody test, selectivity is key.”

Play Episode Listen Later Apr 15, 2020 18:46


Shanti and Elliot announce that ProMIS is beginning to develop a test for Covid-19. They discuss how ProMIS can leverage its existing expertise.

*Re-Release* Episode 4 – How do Biomarkers Work?

Play Episode Listen Later Mar 28, 2020 13:19


We are re-releasing a popular episode about Biomarkers and how they work!

Episode 20 –Dr. José Luis Molinuevo of the BarcelonaBeta Brain Research Center on the Future of Alzheimer's Disease

Play Episode Listen Later Mar 10, 2020 27:48


Shanti and Elliot talk to Dr. José Luis Molinuevo of the BarcelonaBeta Brain Research Center on the Future of Alzheimer's Disease

Episode 19 – Dr. Stephen Salloway, Rhode Island’s Man of the Year, on a brighter future for Alzheimer’s disease

Play Episode Listen Later Feb 17, 2020 23:04


Dr. Stephen Salloway and Dr. James Kupiec reflect on Aducanumab, the exciting progress that has been made in the AD research community over the last 20 years, and the future of AD research.

Episode 18 – Dr. Sharon Cohen Deconstructs the Aducanumab Data From CTAD

Play Episode Listen Later Dec 11, 2019 32:06


This week Shanti and Elliot talk to Dr. Sharon Cohen, director of Toronto Memory Program. They discuss the recent news surrounding aducanumab, as well as Dr. Cohen's recent trip to CTAD.

Episode 17 – The Data Behind Biogen's Recent Decision with Dr. James Kupiec

Play Episode Listen Later Nov 18, 2019 18:26


This week Shanti and Elliot discuss the data behind Biogen's recent decision to revive their Aducanumab study.

Episode 16 – In the news: Biogen and Neuroinflammation with Dr. Johanne Kaplan

Play Episode Listen Later Nov 6, 2019 13:41


This week Shanti and Johanne discuss the recent news coming out of Biogen and how Neuroinflammation relates to Alzheimer's.

Episode 15 – Protein Misfolding Diseases with Dr. Lary Walker

Play Episode Listen Later Oct 4, 2019 17:49


This week Shanti and Elliot talk to Dr. Lary Walker, a research professor at Emory University. They discuss what Alzheimer’s, Parkinson’s and more have in common.

Episode 14 – Finding Treatment for Alzheimer's and Other Diseases with Brain Canada's Inez Jabalpurwala

Play Episode Listen Later Sep 11, 2019 20:01


This week Shanti and Elliot are joined by Brain Canada's CEO Inez Jabalpurwala. They discuss the wonderful work that Brain Canada has been doing, and the next steps in the search for a cure for Alzheimer's, Parkinson's and other diseases.

Episode 13 – Understanding Multiple System Atrophy, Prions and Neuron Death

Play Episode Listen Later Aug 30, 2019 15:58


This week Shanti and Elliot discuss Multiple System Atrophy, prions and how greater understanding of each can help other neurodegenerative diseases.

Episode 12 – A Deeper Dive Into Biomarkers with Dr. James Kupiec Reporting on AAIC Research

Play Episode Listen Later Aug 21, 2019 16:35


This week Shanti is joined by Dr. James Kupiec, Chief Medical Officer at ProMIS Neurosciences. Shanti and Dr. Kupiec do a deep dive on Biomarkers and discuss recent research coming out of AAIC.

Episode 11 – What Is TDP43 and What Are We Going to Do About It?

Play Episode Listen Later Aug 11, 2019 14:03


Elliot is back to discuss the TDP43 protein, which has been implicated in the development of a recently discovered form of dementia as well as ALS. Shanti and Elliot talk about why TDP43 is important, and the efforts to neutralize the misfolded protein in the brain before it can destroy brain cells.

Episode 10 – AAIC 2019 Recap with Dr. Johanne Kaplan

Play Episode Listen Later Jul 23, 2019 13:23


This week Shanti and Dr. Johanne Kaplan recap AAIC 2019 and discuss the exciting data that came out of the conference. For more information check out https://promisneurosciences.com/

Episode 9 – AAIC 2019 Preview with Dr. Johanne Kaplan

Play Episode Listen Later Jul 12, 2019 8:42


This week Shanti and Johanne preview AAIC and discuss what the hot topics at the conference are expected to be.

Episode 8 – 2019 Keystone Symposia Breakdown with Dr. Johanne Kaplan

Play Episode Listen Later Jun 25, 2019 19:20


This week Shanti discusses some of the most exciting news coming out of the recent 2019 Keystone Symposia with Dr. Johanne Kaplan.

Episode 7 – Dr. Johanne Kaplan on the Importance of Selectivity

Play Episode Listen Later Jun 19, 2019 24:00


Shanti is joined by Dr. Johanne Kaplan, the Chief Development Officer at ProMIS Neurosciences. The two discuss Dr. Kaplan's career, and the current challenges researchers must tackle as they continue their search for a way to stop Alzheimer's disease. The two also discuss Dr. Kaplan's recent paper on the importance of selectivity in drug development for Alzheimer's.

Episode 6 – The "One-Two Punch" of Abeta and Tau

Play Episode Listen Later May 28, 2019 13:54


Toxic tau and amyloid-beta are the two most validated drug targets for an Alzheimers disease therapy. Elliot and Shanti discuss tau, its role as a root cause of Alzheimer's disease and its involvement in 80 other diseases known as tauopathies.

Episode 5 – Major Late-stage Alzheimer's Failures

Play Episode Listen Later May 25, 2019 15:09


Dr. Goldstein and Shanti breakdown the news of the week. This week they discuss two major late-stage failures for promising Alzheimer's drugs, a new syndrome that is similar to Alzheimer's, and some important biomarker developments.

Episode 4 – How do Biomarkers Work?

Play Episode Listen Later Mar 27, 2019 13:19


This is part two of our exploration of biomarkers. Elliot and Shanti discuss how biomarkers work and how they will play a critical role in the future of drug development for the various brain-wasting diseases.

Episode 3 – Why Biomarkers Matter

Play Episode Listen Later Mar 15, 2019 13:17


Dr. Goldstein and Shanti discuss why biomarkers are becoming increasingly important in the medical community. They also discuss how biomarkers are uniquely important in the quest for a cure for Alzheimer's.

Episode 2 – Understanding Parkinson's Disease

Play Episode Listen Later Mar 11, 2019 15:12


This week Dr. Goldstein and Shanti discuss Parkinson's disease. They discuss the underlying cause of Parkinson's, treatment options, side effects and the connection between Parkinson's and Alzheimer's

Episode 1 – The Alzheimer's Public Health Crisis

Play Episode Listen Later Feb 23, 2019 14:11


This week our hosts Dr. Elliot Goldstein MD and Shanti Skiffington provide a summary of the current efforts to find a cure for Alzheimer's disease.

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