Podcasts about alzheimer's disease

Quels pouvoirs émotionnels à la musique ? Avez-vous déjà été étonné de voir qu'une musique pouvait vous transporter autant physiquement qu'émotionnellement ? Existe-t-il une musique qui vous replonge immédiatement dans un souvenir ? Est-ce qu'elle vous rappelle la personne avec qui vous étiez au moment de son écoute ? Fait-elle resurgir avec précision les émotions de l'instant où vous l'avez entendue ? Allongé dans son lit, en transit dans un train, ou en courant dans un parc, la musique nous accompagne partout, elle s'insinue dans notre quotidien, dans notre intimité. Mais comment se fait-il qu'elle ait un tel pouvoir sur nos émotions ? Dans ce nouvel épisode, la journaliste Katie Kheriji-Watts s'intéresse au pouvoir libérateur et thérapeutique de la musique. Pour comprendre comment cet art peut permettre de se relever d'un drame et réparer des traumatismes, la journaliste tend son micro à Malika Bellaribi Le Moal, cantatrice professionnelle depuis trente ans. Elle va aussi interroger Chantal Ardouin, dirigeante de Music'O Seniors, une association qui travaille auprès des personnes ayant des troubles de type Alzheimer. Elle explique en quoi la musique a parfois un impact immédiat et surprenant sur eux. Enfin, pour comprendre les effets biologiques et concrets que la musique à sur notre cerveau et sur notre corps, Katie Kheriji-Watts interroge Emmanuel Bigand, enseignant à l'Université de Bourgogne et chercheur en psychologie cognitive, qui explique en quoi la musique peut modifier nos rythmes intérieurs. Quelques références sur le sujet: -Musicophilia - La musique, le cerveau et nous, Oliver Sacks -La symphonie neuronale ; pourquoi la musique est indispensable au cerveau, Emmanuel Bigand, Barbara Tillmann-Le corps n'oublie rien, Bessel van der Kolk -Les étonnants pouvoirs de transformation du cerveau, Norman DoidgeÉmotions est un podcast de Louie Media présenté par Brune Bottero. Cet épisode a été tourné, écrit et monté par la journaliste Katie Kheriji-Watts. L'épisode a été réalisé par Marine Quemere. Guillaume de Lavilleon s'est occupé de la prise de son et Jean-Baptiste Aubonnet du mix. C'est Nicolas de Gélis qui a composé le générique d'Émotions. Maud Benakcha est la chargée de production d'Émotions, accompagnée d'Agathe Le Taillandier et de Capucine Rouault pour cet épisode. Ce podcast est également rendu possible grâce à Maureen Wilson, responsable éditoriale, Marion Girard responsable de production, Mélissa Bounoua directrice des productions et Charlotte Pudlowski, directrice éditoriale. Voir Acast.com/privacy pour les informations sur la vie privée et l'opt-out.

Giants prospect Braden Bishop joins KNBR Tonight with Kerry to talk about starting the 4MOM Charity with his brother Hunter for his mother Suzy Bishop who passed away 2019 after a five-year battle with Alzheimer's See omnystudio.com/listener for privacy information.

Brand new episode!

Did you know that your body has a powerful barrier that helps keep your brain safe from invaders and toxins? This shield, called the blood-brain barrier, can weaken with age. The good news is that resveratrol can help support protection of the brain. Take advantage of an exclusive podcast offer today by visiting http://www.invitehealth.com/podcast. For more information on the products or studies mentioned in this episode, click here.

durée : 01:59:11 - Le 7/9 - par : Nicolas Demorand, Léa Salamé - Professeur Philippe Amouyel, épidémiologiste, professeur de Santé Publique au CHU de Lille, directeur de la fondation Alzheimer, est l'invité du Grand entretien de la matinale

Make yourself comfortable, because we cover a lot of ground in today's episode. Naila will guide you through 24 papers from August 2021, all pertaining to epidemiological studies on the risk and protective factors related to AD. You'll hear about some basic epidemiology, environmental and socioeconomic risk factors, lifestyle factors, and health conditions related to AD. Sections in this episode: Epidemiology & Social Factors (1.52) Diet (16.53) Sleep (24.19) Comorbidities (28.00) -------------------------------------------------------------- You can find the numbered bibliography for this episode by clicking here, or the link below:https://drive.google.com/file/d/1VofighHxFUKtBBcd0w0AHLZmEV9DM-_L/view?usp=sharingTo access the folder with all the bibliographies for 2021 so far, follow this link (it will be updated as we publish episodes and process bibliographies), or click the following link below:https://drive.google.com/drive/folders/1N1zx_itPkCDNYE1yFGZzQxDDR-NiRx3p?usp=sharingYou can also join our mailing list to receive a newsletter by filling this form. Or tweet at us: @AMiNDR_podcast  --------------------------------------------------------------Follow-up on social media for more updates!Facebook:  AMiNDR  Twitter: @AMiNDR_podcastInstagram: @AMiNDR.podcastYoutube: AMiNDR PodcastLinkedIn: AMiNDR PodcastEmail: amindrpodcast@gmail.com  -------------------------------------------------------------- Please help us by spreading the word about AMiNDR to your friends, colleagues, and networks! Another way you can help us reach more listeners who would benefit from the show is by leaving us a review on Apple Podcasts or wherever you listen to podcasts. It helps us a lot and we thank you in advance for leaving a review! Our team of volunteers works together to bring you every episode of AMiNDR. In particular, this episode was scripted and hosted by Naila Kuhlmann, edited by Anusha Kamesh, and reviewed by Elyn Rowe and Ellen Koch. The bibliography was made by Anjana Rajendran and the wordcloud was created by Sarah Louadi (www.wordart.com). Big thanks to the sorting team for sorting all the papers published in August 2021 into themes for our episodes: Jacques Ferreira, Ellen Koch, Nicole Corso, Kate Van Pelt, Christy Yu, Dana Clausen and Elyn Rowe. Also, props to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, and Jacques Ferreira, for keeping everything running smoothly.Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.   https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w   -------------------------------------------------------------- If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, audio editing, creating bibliographies, and outreach/marketing. However, if you are interested in helping in other ways, don't hesitate to apply anyways.  --------------------------------------------------------------*About AMiNDR: *  Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!" 

Eating leafy greens could help prevent macular degeneration Westmead Institute for Medical Research (Australia), October 13, 2021    A new study has shown that eating vegetable nitrates, found mainly in green leafy vegetables and beetroot, could help reduce your risk of developing early-stage age-related macular degeneration (AMD). Researchers at the Westmead Institute for Medical Research interviewed more than 2,000 Australian adults aged over 49 and followed them over a 15-year period. The research showed that people who ate between 100 to 142 mgs of vegetable nitrates each day had a 35% lower risk of developing early AMD than people who ate less than 69mgs of vegetable nitrates each day. Lead Researcher Associate Professor Bamini Gopinath from the Westmead Institute and the University of Sydney said the link between vegetable nitrates and macular degeneration could have important implications. "This is the first time the effects of dietary nitrates on macular degeneration risk has been measured. "Essentially we found that people who ate 100 to 142 mgs of vegetable nitrates every day had a reduced risk of developing early signs of macular degeneration compared with people who ate fewer nitrates. "If our findings are confirmed, incorporating a range of foods rich in dietary nitrates - like green leafy vegetables and beetroot - could be a simple strategy to reduce the risk of early macular degeneration," Associate Professor Gopinath said. Spinach has approximately 20mg of nitrate per 100g, while beetroot has nearly 15mg of nitrate per 100g. The research did not show any additional benefits for people who exceeded 142mgs of dietary nitrate each day. It also did not show any significant connections between vegetable nitrates and late stage AMD, or between non-vegetable nitrates and AMD risk. One in seven Australians over 50 have some signs of macular degeneration. Age is the strongest known risk factor and the disease is more likely to occur after the age of 50. There is currently no cure for the disease. The research compiled data from the Blue Mountains Eye Study, a benchmark population-based study that started in 1992. It is one of the world's largest epidemiology studies, measuring diet and lifestyle factors against health outcomes and a range of chronic diseases. "Our research aims to understand why eye diseases occur, as well as the genetic and environmental conditions that may threaten vision," Associate Professor Gopinath concluded.     Research review shows intermittent fasting works for weight loss, health changes University of Illinois Chicago, October 13, 2021 Intermittent fasting can produce clinically significant weight loss as well as improve metabolic health in individuals with obesity, according to a new study review led by University of Illinois Chicago researchers. "We noted that intermittent fasting is not better than regular dieting; both produce the same amount of weight loss and similar changes in blood pressure, cholesterol and inflammation," said Krista Varady, professor of nutrition at the UIC College of Applied Health Sciences and author of "Cardiometabolic Benefits of Intermittent Fasting."  According to the analysis published in the Annual Review of Nutrition, all forms of fasting reviewed produced mild to moderate weight loss, 1 percent to 8 percent from baseline weight, which represents results that are similar to that of more traditional, calorie-restrictive diets. Intermittent fasting regimens may also benefit health by decreasing blood pressure and insulin resistance, and in some cases, cholesterol and triglyceride levels are also lowered. Other health benefits, such as improved appetite regulation and positive changes in the gut microbiome, have also been demonstrated.  The review looked at over 25 research studies involving three types of intermittent fasting:  Alternate day fasting, which typically involves a feast day alternated with a fast day where 500 calories are consumed in one meal.  5:2 diet, a modified version of alternate day fasting that involves five feast days and two fast days per week.  Time-restricted eating, which confines eating to a specified number of hours per day, usually four to 10 hours, with no calorie restrictions during the eating period.  Various studies of time-restricted eating show participants with obesity losing an average of 3 percent of their body weight, regardless of the time of the eating window.  Studies showed alternate day fasting resulted in weight loss of 3 percent to 8 percent of body weight over three to eight weeks, with results peaking at 12 weeks. Individuals on alternate day fasting typically do not overeat or binge on feast days, which results in mild to moderate weight loss, according to the review.  Studies for the 5:2 diet showed similar results to alternate day fasting, which surprised the study's reviewers. The subjects who participate in the 5:2 diet fast much less frequently than alternate-day fasting participants do, but the weight loss results are similar.  Weight loss with alternate day and 5:2 fasting are comparable to more traditional daily calorie-restrictive diets. And, both fasting diets showed individuals were able to maintain an average of 7 percent weight loss for a year.  "You're fooling your body into eating a little bit less and that's why people are losing weight," Varady said.  Varady added the review set out to debunk some myths regarding intermittent fasting. Intermittent fasting does not negatively affect metabolism, nor does it cause disordered eating, according to the studies reviewed.  "Fasting people are worried about feeling lethargic and not being able to concentrate. Even though you are not eating, it won't affect your energy," Varady said. "A lot of people experience a boost of energy on fasting days. Don't worry, you won't feel crappy. You may even feel better."  The study review includes a summary of practical considerations for those who may want to try intermittent fasting. Among the considerations are:  Adjustment time—Side effects such as headaches, dizziness and constipation subside after one to two weeks of fasting. Increased water intake can help alleviate headaches caused by dehydration during this time.  Exercise—Moderate to high-intensity endurance or resistance training during food abstention can be done, and some study participants reported having more energy on fast days. However, studies recommend those following alternate day fasting eat their fasting day meal after exercise.  Diet during fasting—There are no specific recommendations for food consumption during intermittent fasting, but eating fruits, vegetables and whole grains can help boost fiber intake and help relieve constipation that sometimes accompanies fasting.  Alcohol and caffeine—For those using an alternate day or 5:2 fasting plan, alcohol is not recommended on fast days as the limited calories should be used on healthy foods that provide nutrition.  There are several groups who should not intermittent fast, according to the studies. Those individuals include:  Those who are pregnant or lactating.  Children under 12.  Those with a history of disordered eating.  Those with a body mass index, or BMI, less than 18.5. Shift workers. Studies have shown they may struggle with fasting regimens because of shifting work schedules.  Those who need to take medication with food at regimented times.  "People love intermittent fasting because it's easy. People need to find diets that they can stick to long term. It's definitely effective for weight loss and it's gained popularity because there are no special foods or apps necessary. You can also combine it with other diets, like Keto," Varady said.  Varady has recently been awarded a National Institutes of Health grant to study time-restricted eating for 12 months to see if it works long term.   Antioxidants to prevent Alzheimer's disease A balanced intake of antioxidants could prevent the development of Alzheimer's disease. Institut National de la Recherche Scientifique (France), October 13, 2021 Research conducted by the Ph.D student Mohamed Raâfet Ben Khedher and the postdoctoral researcher Mohamed Haddad of the Institut national de la recherche scientifique (INRS) has shown that an oxidation-antioxidant imbalance in the blood is an early indicator of Alzheimer's disease, rather than a consequence. This breakthrough made by researchers under the supervision of the Professor Charles Ramassamy provides an avenue for preventive intervention: the antioxidants intake.  The research team showed that oxidative markers, known to be involved in Alzheimer's disease, show an increase up to five years before the onset of the disease. The results of this study, published in the Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring (DADM) journal, suggest that oxidation may be an early marker of this disease that affects more than 500,000 Canadians. “Given that there is an increase in oxidative stress in people who develop the disease, we may regulate the antioxidant systems. For example, we could modulate the antioxidant systems, such as apolipoproteins J and D, which transport lipids and cholesterol in the blood and play an important role in brain function and Alzheimer's disease. Another avenue would be to increase the intake of antioxidants through nutrition”, says Professor Ramassamy.  Accessible biomarkers Unlike the current set of invasive and expensive tests used to diagnose Alzheimer's disease, the oxidative markers discovered by Professor Ramassamy's research team can be detected by a blood test. These markers are found in plasma extracellular vesicles, which are pockets released by all cells in the body, including those in the brain.     The research team focused specifically on the "sporadic" Alzheimer's disease, the most common form of the disease which results primarily from the presence of the APOE4 susceptibility gene. This same form of the disease had been studied by the team for other early markers. “By identifying oxidative markers in the blood of individuals at risk five years before the onset of the disease, we could make recommendations to slow the onset of the disease and limit the risks”, scientists noted. This breakthrough brings new hope to Alzheimer's research. Once the disease is symptomatic, it is difficult, if not impossible, to reverse it.         Meditation training reduces long-term stress, according to hair analysis Max Planck Institute for Human Cognitive and Brain Sciences (Germany), October 11, 2021 Mental training that promotes skills such as mindfulness, gratitude or compassion reduces the concentration of the stress hormone cortisol in hair. This is what scientists from the Max Planck Institute for Human Cognitive and Brain Sciences in Leipzig and the Social Neuroscience Research Group of the Max Planck Society in Berlin have found out. The amount of cortisol in hair provides information about how much a person is burdened by persistent stress. Earlier positive training effects had been shown in acutely stressful situations or on individual days—or were based on study participants' self-reports. According to a study by the Techniker Krankenkasse, 23 percent of people in Germany frequently suffer from stress. This condition not only puts a strain on the well-being of those affected, but it is also linked to a number of physiological diseases, including diabetes, cardiovascular diseases and psychological disorders such as depression, one of the world's leading causes of disease burden (Global Burden of Disease Study, 2017). Therefore, effective methods are being sought to reduce everyday stress in the long term. One promising option is mindfulness training, in which participants train their cognitive and social skills, including attention, gratitude and compassion, through various meditation and behavioral exercises. Various studies have already shown that even healthy people feel less stressed after a typical eight-week training program. Until now, however, it has been unclear how much the training actually contributes to reducing the constant burden of everyday stress. The problem with many previous studies on chronic stress is that the study participants were usually asked to self-assess their stress levels after the training. However, this self-reporting by means of questionnaires could have distorted the effects and made the results appear more positive than they actually were. The reason for such a bias: The participants knew they were training their mindfulness, and a reduction in stress levels was a desired effect of this training. This awareness alone has an impact on subsequent information. "If you are asked whether you are stressed after a training session that is declared as stress-reducing, even addressing this question can distort the statements," explains Lara Puhlmann, doctoral student at the Max Planck Institute for Human Cognitive and Brain Sciences and first author of the underlying publication, which has now appeared in the journal Psychosomatic Medicine. Factors such as social desirability and placebo effects played a role here. Unlike pharmacological studies, for example, in which the study participants do not know whether they have actually received the active substance or not, so-called blinded studies are not possible in mental training. "The participants know that they are ingesting the 'antidote,'" says Puhlmann. "In mindfulness research, we are therefore increasingly using more objective, i.e. physiological, methods to measure the stress-reducing effect more precisely." The concentration of cortisol in hair is considered a suitable measure of exposure to prolonged stress. Cortisol is a hormone that is released when we are confronted with an overwhelming challenge, for example. In that particular situation, it helps put our body on alert and mobilize energy to overcome the challenge. The longer the stress lasts, the longer an increased concentration of cortisol circulates around our body—and the more it accumulates in our hair. On average, hair grows one centimeter per month. To measure the study participants' stress levels during the 9-month training, the researchers, in cooperation with the working group of Clemens Kirschbaum at the University of Dresden, analyzed the amount of cortisol every three months in the first three centimeters of hair, starting at the scalp. The mental training itself was developed as part of a large-scale longitudinal study on the effects of mental training, the ReSource project, led by Tania Singer, scientific director of the Social Neuroscience Research Group. This 9-month mental training program consisted of three 3-month sessions, each designed to train a specific skill area using Western and Far Eastern mental exercises. The focus was either on the factors of attention and mindfulness, on socio-affective skills such as compassion and gratitude, or on so-called socio-cognitive skills, in particular the ability to take perspective on one's own and others' thoughts. Three groups of about 80 participants each completed the training modules in different order. The training lasted up to nine months, 30 minutes a day, six days a week. Less stress, less cortisol And it really showed: After six months of training, the amount of cortisol in the subjects' hair had decreased significantly, on average by 25 percent. In the first three months, slight effects were seen at first, which increased over the following three months. In the last third, the concentration remained at a low level. The researchers therefore assume that only sufficiently long training leads to the desired stress-reducing effects. The effect did not seem to depend on the content of the training. It is therefore possible that several of the mental approaches studied are similarly effective in improving the way people deal with chronic everyday stress. In an earlier study from the ReSource project with the same sample, the researchers had investigated the effects of training on dealing with acute stressful situations. In this study, the participants were placed in a stressful job interview and had to solve difficult maths problems under observation. The results showed that people who had undergone socio-cognitive or socio-affective training released up to 51 percent less cortisol under stress than those who had not been trained. In this case, they did not measure the amount of cortisol in the subjects' hair, but instead acute cortisolsurges in their saliva. Overall, the researchers conclude that training can improve the handling of acute particularly stressful social situations as well as chronic everyday stress. "We assume that different training aspects are particularly helpful for these different forms of stress," says Veronika Engert, head of the research group "Social Stress and Family Health" at the Max Planck Institute for Human Cognitive and Brain Sciences. "There are many diseases worldwide, including depression, that are directly or indirectly related to long-term stress," explains Puhlmann. "We need to work on counteracting the effects of chronic stress in a preventive way. Our study uses physiological measurements to prove that meditation-based training interventions can alleviate general stress levels even in healthy individuals."   Study: Moderate carbohydrate intake is a cardiovascular benefit for women Monash University (Australia), October 13, 2021 Women's heart health has been the focus of a recent study by Monash University, with researchers finding that proportional carbohydrate intake and not saturated fat was significantly associated with cardiovascular disease benefit in Australian women. Cardiovascular disease (CVD) is the leading cause of death in women. Poor diet is recognized as both an independent CVD risk factor and a contributor to other CVD risk factors, such as obesity, diabetes mellitus (DM), hypertension, and dyslipidaemia. The research found that in middle-aged Australian women, increasing the percentage of carbohydrate intake was significantly associated with reduced odds of CVD, hypertension, diabetes mellitus, and obesity. Furthermore, a moderate carbohydrate intake between 41.0 percent—44.3 percent of total energy intake was associated with the lowest risk of CVD compared to women who consumed less than 37 percent energy as carbohydrates. No significant relationship was demonstrated between proportional carbohydrate intake and all-cause mortality. In addition, increasing proportional saturated fat intake was not associated with cardiovascular disease or mortality in women; rather, increasing saturated fat intakecorrelated with lower odds of developing diabetes mellitus, hypertension, and obesity. The findings are now published in the British Medical Journal. The results contradict much of the historical epidemiological research that supported a link between saturated fat and CVD. Instead, the results mirror contemporary meta-analysis of prospective cohort studies where saturated fat was found to have no significant relationship with total mortality or CVD. While the cause of this inconsistency in the literature is unclear, it has been suggested that historical studies neglected to adjust for fiber, which is known to help prevent plaque from forming in the arteries. "Controversy still exists surrounding the best diet to prevent CVD," said Sarah Zaman, a former Monash University professor who is now an associate professor at the University of Sydney. "A low-fat diet has historically been the mainstay of primary prevention guidelines, but the major issue within our dietary guidelines is that many dietary trials have predominately involved male participants or lacked sex-specific analyses." She adds: "Further research is needed to tailor our dietary guidelines according to sex." The study's first author Sarah Gribbin, a Doctor of Medicine and BMedSc (Hons) student, says: "As an observational study, our findings only show association and not causation. Our research is purely hypothesis-generating. We are hoping that our findings will spark future research into sex-specific dietary research." The Heart Foundation, which is one of the study's funders, welcomed the focus on women and CVD, which has historically been under-researched. Heart Foundation manager, food and nutrition, Eithne Cahill, cautioned that "not all carbohydrates are created equal." "We know that quality carbohydrate foods such as vegetables and whole grains—including whole grain bread, cereals, and pasta—are beneficial for heart health, whereas poor quality carbohydrates such as white bread, biscuits, cakes, and pastries can increase risk," she said. "Similarly, different fats have different effects on heart health. That is why the Heart Foundation focuses on healthy eating patterns—that is, a combination of foods, chosen regularly over time—rather than a single nutrient or food. Include plenty of vegetables, fruit, and whole grains, and heart-healthy fat choices such as nuts, seeds, avocados, olives and their oils for cooking and a variety of healthy proteins especially seafood, beans and lentils, eggs and dairy."   Anti-cancer effects found in natural compound derived from onions   Kumamoto University (Japan), October 18, 2021   Research from Kumamoto University, Japan has found that a natural compound isolated from onions, onionin A (ONA), has several anti-ovarian cancer properties. This discovery is a result of research on the effects of ONA on a preclinical model of epithelial ovarian cancer (EOC) both in vivo and in vitro. This research comes from the same group that found ONA suppressed pro-tumor activation of host myeloid cells.   According to a 2014 review of cancer medicines from the World Health Organization, EOC is the most common type of ovarian cancer and has a 5-year survival rate of approximately 40%. It has a relatively low lifetime risk that is less than 1%, but that can increase up to 40% if there is a family history of the disease. A majority of patients (80%) experience a relapse after their initial treatment with chemotherapy, therefore a more effective line of treatment is needed.   Kumamoto University researchers found that ONA has several effects on EOC. The group's in vitro experiments showed that EOCs, which usually proliferate in the presence of pro-tumor M2 macrophages, showed inhibited growth after introduction of ONA. This was thought to be due to ONAs influence on STAT3, a transcription factor known to be involved in both M2 polarization and cancer cell proliferation. Furthermore, the team found that ONA inhibited the pro-tumor functions of myeloid derived suppressor cells (MDSC), which are closely associated with the suppression of the anti-tumor immune response of host lymphocytes, by using preclinical sarcoma model. ONA was also found to enhance the effects of anti-cancer drugs by strengthening their anti-proliferation capabilities. Moreover, experiments on an ovarian cancer murine model that investigated the effects of orally administered ONA resulted in longer lifespans and inhibited ovarian cancer tumor development. This was considered to be a result of ONA's suppression of M2 polarized macrophages.   The research shows that ONA reduces the progression of malignant ovarian cancer tumors by interfering with the pro-tumor function of myeloid cells. ONA appears to activate anti-tumor immune responses by nullifying the immunosuppressive function of myeloid cells. ONA has the potential to enhance existing anti-cancer drugs while also having little to no cytotoxic effects on normal cells. Additionally, side effects in animals have not been seen. With a little more testing, an oral ONA supplement should greatly benefit cancer patients.     Risk of chronic diseases caused by exogenous chemical residues Dalian Institute of Chemical Physics (China), October 13, 2021 Chronic diseases are main killers affecting the health of human. The morbidities of major chronic diseases such as obesity, hypertension, diabetes, hyperuricemia and dyslipidemia are as high as 10% to 30%, showing a gradually upward trend as well. More and more studies have shown that environmental pollution is a major health risk factor that cannot be ignored. However, the evidence for their relationship is equivocal and the underlying mechanisms is unclear. Recently, a research group led by Prof. Xu Guowang from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS) discovered the risk of chronic diseases caused by exogenous chemical residues through metabolome-wide association study. Their findings were published in Environment International on Oct. 8. Researchers from National Institute for Nutrition and Health of the Chinese Center for Disease Control and Prevention, and Tongji Medical College of Huazhong University of Science and Technology were also involved in this study. The researchers discovered positive associations of serum perfluoroalkyl substances (PFASs) with hyperuricemia, and revealed the mechanism of the relationship between the exogenous chemical residues in the serum and the risk of chronic diseases at the metabolic level. The researchers investigated the relationship between 106 exogenous chemical residues and five chronic diseases in 496 serum samples. They revealed the metabolic perturbations related to exogenous chemical residues and chronic diseases by the metabolome-wide association study combined with meeting-in-the-middle approach and mediation analysis, and investigated the further potential underlying mechanism at the metabolic level. "PFASs were the risk factor for hyperuricemia," said Prof. Xu. Lipid species including glycerophospholipids and glycerides presented the strongest correlation with exposure and disease, which were not only positively related to PFASs exposure but also the risk factor for hyperuricemia. "We also found that key mediation metabolites mediated 25% to 68% of the exposure-disease risk relationship," Prof. Xu added. This study provides in-depth etiological understanding for the occurrence and development of diseases, which may be helpful for the early detection of the disease and the identification of early warning markers.

Comenzamos con lo que esta sucediendo en la clínica de vacunación para gente con Alzheimer, ademas de lo que esta haciendo Earthship PR y por supuesto que Estados Unidos no reconoce la vacuna hecha en Cuba para el famoso virus. Tema Principal

This week we talk with author Susan Cushman about her new book titled "John and Mary Margaret". A book that tackles the world of race relations in the 1960's South, namely between two Ole Miss college students who fall in love. We learn about what inspired her to write the book and how parts are reflective of her own upbringing. There is a theme in the book about Alzheimer's and Lewy Body Dementia as well that we speak on. We also talk about how the writing process works for her and tips she has for others. This was a thought provoking interview and one I think everyone can learn something from.--------------------------------------------Link to pickup John and Mary Margaret: http://www.shorturl.at/uG237Susan's Website: https://susancushman.com/---------------------------------------------Podcast's Instagram: https://www.instagram.com/notinahuffpodcast/Please follow and/or subscribe to the podcast to get the new episodes when they come out each week and rate us on Apple Podcast! :)

What can you do when you're not feeling great about yourself and things are hard? Step back and ask yourself a few key questions to better understand what lesson the situation is teaching you. Just asking yourself questions gives you the ability to reframe how you think about the circumstance — once you reframe your thinking your feelings will follow. During this solo episode of the Intentional Greatness® podcast, Sue shares seven things to focus on to become more effective and kickass in life. What you'll learn about in this episode: The seven things to focus on to become more effective What questions to ask yourself when you are struggling in life How Sue's mothers Alzheimer's impacted her priorities How to leave the world better than you found it Why you should lower your expectations and assume nothing How to make peace with the past by telling your story in a way that forwards you Resources: Online Learning Community: yess.learnworlds.com Website: https://www.sayyess.com/ Books: https://www.sayyess.com/books/ LinkedIn: https://www.linkedin.com/in/suehawkes/ https://www.linkedin.com/company/suehawkesyess/ Facebook: https://www.facebook.com/YESScoaching Twitter: https://twitter.com/SueHawkesYESS Reframing Questions What can you do when you're not feeling great about yourself and things are hard? Step back and ask yourself a few key questions to better understand what lesson the situation is teaching you. Just asking yourself questions gives you the ability to reframe how you think about the circumstance — once you reframe your thinking your feelings will follow. During this solo episode of the Intentional Greatness® podcast, Sue shares seven things to focus on to become more effective and kickass in life. Leaving it Better Always do more than what's expected of you. Leave the world a better place than you found it. What is expected of you, is doing the bare minimum. What would the world be like if everyone were to only do the minimum in their personal lives or work lives? Challenge yourself to exceed expectations whenever possible. Do not overextend yourself. But, if you can offer a little bit more than expected, you can leave an indelible mark on someone. Moving Forward Do not fall in love with your story. When someone tells a story, they know how to elicit a specific response, and they often tell it differently depending on the audience. No one else is as in love with your story as you are. You are the author of your own story, and you have the opportunity to tell it in a way that allows you to make peace with the past by telling the story of how it catalyzed you and how it made you better. Use your story to move yourself forward.

In this episode, we are shining the caregiver spotlight on Richard Lui. Richard Lui is a veteran and award-winning journalist. You'll find him currently on MSNBC. He is the first Asian American man to anchor a daily national cable news program, and a team Emmy and Peabody winner. When his dad was diagnosed with Alzheimer's disease, Richard made a tough decision – he put his successful career on the back burner to help care for his dad. This selflessness didn't come easy for him and he writes about this in his new book Enough About Me: The Unexpected Power of Selflessness. Richard also completed a powerful documentary on young caregivers in military families. In this episode, we talk about all of Richard's current projects plus mental self-care practices, pivots during the caregiving journey, and seeking the flexibility you need in your professional career. Show notes with product and resource links: https://bit.ly/HHCPod124 Receive the podcast in your email here: http://bit.ly/2G4qvBv Order a copy of Elizabeth's book Just for You: a Daily Self Care Journal: http://bit.ly/HHCjournal For podcast sponsorship opportunities contact Elizabeth: https://happyhealthycaregiver.com/contact-us/ The Happy Healthy Caregiver podcast is part of the Whole Care Network. Rate and Review the podcast: https://bit.ly/HHCPODREVIEW

The Dr. John Delony Show is a caller-driven show that offers real people a chance to be heard as they struggle with relationship issues and mental health challenges. John will give you practical advice on how to connect with people, how to take the next right step when you feel frozen, and how to cut through the depression and anxiety that can feel so overwhelming. You are not alone in this battle. You are worth being well—and it starts by focusing on what you can control. Let us know what's going on by leaving a voicemail at 844.693.3291 or visiting johndelony.com/show. We want to talk to YOU!   Show Notes for this Episode Dad has Alzheimer's & we're dealing with family drama around it Mom has cancer & my sister-in-law is being a martyr about her care How can I help my husband grapple with his childhood abuse? Lyrics of the Day: "Don't You Want To Thank Someone" - Andrew Peterson   As heard on this episode:  BetterHelp dreamcloudsleep.com/delony Conversation Starters Redefining Anxiety John's Free Guided Meditation Ramsey+   tags: sickness/illness, family, anger/resentment/bitterness, disagreement/conflict, grief, abuse, boundaries, trauma/PTSD   These platforms contain content, including information provided by guests, that is intended for informational and entertainment purposes only. The content is not intended to replace or substitute for any professional medical, counseling, therapeutic, financial, legal, or other advice. The Lampo Group, LLC d/b/a Ramsey Solutions as well as its affiliates and subsidiaries (including their respective employees, agents and representatives) make no representations or warranties concerning the content and expressly disclaim any and all liability concerning the content including any treatment or action taken by any person following the information offered or provided within or through this show. If you have specific concerns or a situation in which you require professional advice, you should consult with an appropriately trained and qualified professional expert and specialist. If you are having a health or mental health emergency, please call 9-1-1 immediately.

The Rev. Brad Sullivan Emmanuel Episcopal Church October 17, 2021 Proper 24, B Mark 10:35-45 Be a Friendly, Neighborhood Spider-Man In the movie Spider-Man: Homecoming, Spider-Man, aka Peter Parker, desperately wants to be an Avenger. The Avengers, such as Iron Man, Captain America, and Black Widow, are Earth’s mightiest superheroes. Their base of operations is Avengers Tower, they are known throughout the world, and they are the ones you call when the really big bad stuff happens. Spider-Man has superpowers, and at the same time, he’s a teenager, Peter Parker, still in high school. His quest to be an Avenger keeps being denied, and he is discouraged because he has lofty ambitions, and wants to do more than just help the people of his neighborhood, Queens, New York. He wants to be saving the world. He wants a spot at Avengers Tower. Well, through all the twists and turns of the movie, eventually, he is offered a place among the Avengers, but by that time, he’s come to see the value not only of “saving the world,” but also the value of being there for the people around him. He turns down the offer to be an Avenger, saying, “Well, I mean, I'd rather just stay on the ground for a little while[, be a] friendly neighborhood Spider-Man. Somebody's got to look out for the little guy, right?” He didn’t need glory. He didn’t need fame. Look out for the little guy, and be a friendly neighborhood Spider-Man. When James and John, the sons of Zebedee asked Jesus to sit next to Jesus when he came into his glory, they were basically wanting to be Avengers. They thought Jesus was going to rule over Israel as king, and so they wanted to sit on either side of his throne. Of course this first meant fighting a war against Rome with Jesus at the helm, and after destroying the Romans and avenging Israel, they would rule over Israel with Jesus. They misunderstood of course one thing, that Jesus wasn’t going to be fighting any war against Rome. They also misunderstood their role, their importance, and their need for a throne in order to be effective as disciples of Jesus. Notice that Jesus didn’t rebuke them for their request. The other disciples did, they were pretty hacked off about it, but Jesus saw that James and John were actually thinking too little of themselves, as if they didn’t matter without some throne, as if they couldn’t really make a difference without a throne. So, Jesus calmed his disciples, called them to him, and taught them a lesson about who they were and what their ministry really was. “You know that among the Gentiles,” Jesus said, “those whom they recognize as their rulers lord it over them, and their great ones are tyrants over them. But it is not so among you…” He didn’t say “it should not be so among you;” that you shouldn’t be tyrants over each other. Jesus said, “it is not so among you.” “You are not tyrants over each other.” Rather than rebuke James and John, Jesus looked into their hearts and saw not a desire for tyranny or greatness for their own sake. Jesus saw a desire for good, and in his response, Jesus is basically saying, Y’all are asking for greatness, and knowing your hearts, I can see that you aren’t asking to be tyrants over others. Your hearts are in the right place. What you are asking for is a serving role, but you don’t need a throne to do that. You already serve, even in seeming lowliness. The service you are doing is just as important and often more important than that of lords of rulers. Keep your feet on the ground for a while. Be a friendly neighborhood Spider-Man. That’s where we find the most effective and Christ-like ministry has been throughout the church. The church as Empire is not what grew disciples of Jesus and healed peoples’ lives. The church as mighty and ruling over others has actually ended up causing a lot of harm in the name of Jesus. No, the real ministry of Jesus through the people of his church happened in the people of the church serving with each other and serving with those in their neighborhoods, looking out for the little guys. The same is true in our world today. Now, this is not to say that there is not good ministry being done by the church on an institutional, organizational level. There is much good ministry being done through the organizations and institutions of the church engaging with other organizations and institutions, even globally. There has just been formed an Episcopal Church delegation to the United Nations for an upcoming UN conference in Glasgow, Scotland. Ellen Singer, from our diocese, will be part of that Episcopal Church delegation to the United Nations. That’s pretty cool. That’s global-level influence of the Episcopal Church. Now, when I first heard of that UN Delegation, my reaction was about like Spider-Man wanting to be an Avenger or James and John wanting to be next to Jesus in his glory. I thought, “I want to go to the United Nations,” but then I quickly realized, “Yeah, actually I really don’t.” I’m glad for those who do. There is great ministry that is done within large bodies, organizations, institutions, and that’s a good thing for the church to be able to offer counsel for those making decisions that affect many, or most, or all. Not to be in charge as Lords over people, but to counsel those who are. Even so, the majority of Jesus’ ministry through the people of his church happens in the neighborhood. The majority of Jesus’ ministry through the people of his church happens in the relationships we have and the relationships we continue to cultivate and form. We don’t need titles, or thrones, or global-level influence to do important ministry as disciples of Jesus. Helping the kids and teachers at Rhoads Elementary is important ministry, looking out for the little guy. Ministering to people with Alzheimer’s and Dementia through The Gathering Place is important ministry, looking out for the little guy. Calling your friend or neighbor who is having a rough time and having some coffee or lunch together to connect and go through that time with that person is important ministry, looking out for the little guy. No one needs to be an Avenger to be a disciple of Jesus. We just need to look out for the little guy, keep our feet on the ground, and be a friendly neighborhood Spider-Man.

You've probably heard about the benefits of omega-3 fatty acids, but what do you know about DHA? Learn all about why this nutrient is important for brain development from Amanda Williams, MPH. Take advantage of an exclusive podcast offer today by visiting http://www.invitehealth.com/podcast. For more information on the products or studies mentioned in this episode, click here. 

Dr. Elena is back to discuss with us preventing dementia. I have a family history of cognitive decline. Preventing dementia, Alzheimer's, any neurodegenerative disease is a big part of how I live my life. The longer I do this podcast, the more I learn. Dynamic learning is one of the most important ways to help our brains live as long as our bodies. What is active learning? The simple answer is learning anything new that requires our focus and concentration. Learning how to ballroom dance or speak a foreign language are good examples of dynamic or active learning. Learning math would probably be a tremendous challenge for me, but it causes emotional distress so that it won't happen. We should all be aware that eating right, exercise, getting good sleep are all important in preventing dementia. Keeping stress under control is also very important. One factor that I don't see discussed as much is dealing with depression. Many years ago, I read that it's believed that many people who have dementia had low levels of depression for much of their adult lives. I wouldn't say my Mom was depressed in the way we generally think of depression, but I do know that she lived with an elevated sense of frustration most of my life. I think that is closely related and worth exploring more. That's what we're doing in the podcast today. Dr. Elena is back to give us her medical opinions on what we need to do to prevent or reduce our risk of dementia. Other Dr Elena Episodes “Accidents” And Aging – Learn How To Avoid Them Fall Prevention with Dr. Elena Medications & Memory with Dr. Elena Frailty Is A Thing? W/Dr. Elena Mucci   NeuroReserve - Helping Our Brainspan Match our Lifespan NeuroReserve - Helping Our Brainspan Match our Lifespan Be sure to check out our website for more resources, partners, recipes, and more.  www.fadingmemoriespodcast.com Join Fading Memories On Social Media! If you've enjoyed this episode, please share this podcast with other caregivers!  You'll find us on social media at the following links. Facebook    Instagram    Twitter Subscribe to our YouTube channel. There you can see me in "action" and watch the bonus videos I share. Want to learn from Jennifer in person (or virtually)? Wherever you'd like a training session, Jen is available. Contact her at fadingmemoriespodcast@gmail.com  

In this week's episode, Sid Evans, Editor-in-Chief of Southern Living Magazine, talks to Alabama native and Grammy-nominated soul vocalist Anderson East about his job as a teenager slinging barbeque, his mother's church piano which he now uses in his own studio, and how the title track from his latest album Maybe We Never Die was influenced by his grandmother's battle with Alzheimer's.  Learn more about your ad choices. Visit megaphone.fm/adchoices

This week, we proudly present an interview with Lauren Miller Rogen, Filmmaker, Alzheimers Advocate, co-founder of HFC, and now friend of Remember Me. Lauren openly shares her mother Adele's journey with early onset Alzheimers disease... and she shares the journey with such honesty, vulnerability and love. She talks about what it was like to try and start her life in Los Angeles while her conflicted heart wanted to be back in Florida with her mom - a feeling many of us know all too well. And of course, we talk all about her incredible mom - who she was before the disease - an amazing teacher and mother. This conversation was so relatable - the feelings, the heartache, it is all the same to what we felt with our own parents... and Lauren did an amazing job of showing us her accept the good outlook - creating a beautiful community and incredible resources through HFC. Below, you'll find a link to our blog post with some great resources from HFC that we think you should check out ASAP: 5 HFC Resources You Should Check Out Now Thank you to Lauren (and to Seth) for the amazing work they are doing for this community. For giving this community a voice. We are so thankful. xx R + M Let us know what you think of the episode by commenting on the episode art on instagram @remembermepodcast Today's Sponsors: --- Want more Remember Me? Join our Re-Members Only Space for extra podcasts, events + more at www.remembermeftd.com/joinro --- Shop for vinyl records at Vnyl Confessions - go to vnylconfessions.com and use code REMEMBER ME for 20% off at checkout --- Neuroreserve: Click here to learn more about NeuroReserve and purchase their brain-health supplement RELEVATE and be sure to use code REMEMBERME for 15% off your order (including monthly subscriptions!) www.neuroreserve.com --- Learn more about remember me at www.remembermeftd.com/ --- Remember Me is a podcast created by two moms who became fast friends on Instagram while caregiving for their parents. It features stories of Frontotemporal Dementia (FTD) with a focus on remembering individuals for who they were before the disease. The stories shared are raw, real, and so full of love. We hope it inspires you to "accept the good." --- Support this podcast: https://anchor.fm/rememberme/support

Every week, Dr. Roizen discusses the latest health headlines YOU need to know.In this episode, Dr. Roizen talks about the latest health headlines that YOU need to know. Scientists untangle way diabetes might raize Alzheimers risk  Physical activity reduces cardiovascular mortality substantially  Fruit & veggies - a recipe for mental health wellbeing Asthma, smoking tied to early COPD risk  Is it safe to drink "Profee" to jumpstart your day? FDA unveils proposed changes to OTC sunscreen labeling PLUS so much more...    

“If you can not measure it, you can not improve it.” - William Thompson Getting regular checkups and undergoing blood tests are fundamental to maintaining good health. FMF guests with expertise ranging from lipid metabolism to Alzheimer's disease risk to micronutrient status have shared their recommendations regarding blood tests that a person should consider adding to their yearly checkup. This Aliquot brings many of those conversations together in one place.   Get more Aliquots! Become a FMF Premium member and get full access to our members-only podcast, The Aliquot, plus live Q&As with Rhonda, biweekly Science Digest emails, and more.   Learn more and sign up at: www.foundmyfitness.com/aliquot

Tired of the age-old amyloid cascade hypothesis? Think there's more to Alzheimer disease than amyloid and tau? Join Elyn in unpacking the latest literature on vascular contributions to Alzheimer disease from papers published in August 2021. This is another relatively short one, packed with exciting new insights!  Sections in this episode:  Cardiovasular Risk Factors (4:30)  White Matter Hyperintensities and Cerebral Small Vessel Disease (8:28)  Vascular Changes: Perivascular Spaces, Pericyte Coverage, & Vessel Density (16:22)  -------------------------------------------------------------- You can find the numbered bibliography for this episode by clicking here, or the link below:https://drive.google.com/file/d/14v5JcU7sGQokNnrveje7ssM_G_UiUQbO/view?usp=sharingTo access the folder with all the bibliographies for 2021 so far, follow this link (it will be updated as we publish episodes and process bibliographies), or click the following link below:https://drive.google.com/drive/folders/1N1zx_itPkCDNYE1yFGZzQxDDR-NiRx3p?usp=sharingYou can also join our mailing list to receive a newsletter by filling this form. Or tweet at us: @AMiNDR_podcast  --------------------------------------------------------------Follow-up on social media for more updates!Facebook:  AMiNDR  Twitter: @AMiNDR_podcastInstagram: @AMiNDR.podcastYoutube: AMiNDR PodcastLinkedIn: AMiNDR PodcastEmail: amindrpodcast@gmail.com  -------------------------------------------------------------- Please help us by spreading the word about AMiNDR to your friends, colleagues, and networks! Another way you can help us reach more listeners who would benefit from the show is by leaving us a review on Apple Podcasts or wherever you listen to podcasts. It helps us a lot and we thank you in advance for leaving a review! Our team of volunteers works together to bring you every episode of AMiNDR. In particular, this episode was scripted and hosted by Elyn Rowe, edited by Michelle Grover, and reviewed by Jacques Ferreira and Sarah Louadi. The bibliography was made by Jacques Ferreira and the wordcloud was created by Sarah Louadi (www.wordart.com). Big thanks to the sorting team for sorting all the papers published in August 2021 into themes for our episodes: Jacques Ferreira, Ellen Koch, Nicole Corso, Kate Van Pelt, Christy Yu, Dana Clausen and Elyn Rowe. Also, props to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, and Jacques Ferreira, for keeping everything running smoothly.Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.   https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w   -------------------------------------------------------------- If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, audio editing, creating bibliographies, and outreach/marketing. However, if you are interested in helping in other ways, don't hesitate to apply anyways.  --------------------------------------------------------------*About AMiNDR: *  Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!" 

Happy Halloween! Emmy-nominated actor Michelle Ang (The Tribe, Outrageous Fortune) joins us as we celebrate the spooky season with a look back at The Taking of Deborah Logan (2014), a found footage possession thriller directed by Adam Robitel (Escape Room). In it, our guest plays a student, Mia, who gets more than she bargained for when she tries to make a documentary focusing on Deborah Logan (Jill Larson), a sufferer of Alzheimers. As Deborah's behaviour becomes more disturbing and strange events plague the house, Mia joins forces with the patient's daughter, Sarah (Anne Ramsay), to uncover the town's dark secret, and a shadowy force that may be trying to complete its terrifying reign of terror from beyond the grave! But is this an undiscovered thrilling gem or forgettable found footage fodder? Find out! Follow our special guest, Michelle Ang, on Twitter and Instagram. Follow us on Twitter, Facebook and Instagram Support us on Patreon to nominate future films and access exclusive bonus content

Untreated and unresolved trauma is now considered to be a risk factor and contributor to Alzheimer's dementia.    Trauma can be defined as any event that alters how we process, react to, and recall memories, by overwhelming the individual's central nervous system. Additionally, trauma is defined as any event in which a person feels helpless and unsafe. It is not only an occurrence that happened in the past; instead, trauma is an event that leaves an imprint upon the body and the brain which persists to the present day.   Our guest for this episode, Dr. Ilene Naomi Rusk completed her PhD in Neuropsychology and Psychopharmacology in the UK , and Fellowships in Neuropsychology.  She has dedicated her career to studying novel treatment strategies for Alzheimer's Disease and sees trauma as a root cause of many illnesses. She is the author of several peer reviewed articles. Dr Rusk co-founded the Brain and Behavior Clinic over 25 years ago and currently directs the Healthy Brain Program in Colorado.   4:20 - Defining trauma through reflecting on a patient story  7:26 - How trauma influences more than just the brain  16:06 - A trauma informed approach to treating neuro degeneration  21:50 - Identifying cognitive decline symptoms in patients who struggle with other mental illnesses or trauma  33:24 - Classic signs of unresolved trauma in the older generations  42:44 - How to deal with unresolved trauma in someone before it becomes cognitive decline  56:12 - How long does it take to see improvement when working with trauma-informed techniques?    Strategies to improve the brain and nervous system: traditional talk therapy (eg with a psychologist) Simple deep breathing dance and movement waling Qi Gong, Tai Chi, Yoga other coregulatory exercises DisasterShock.com is a resource for people struggling with the stressors and traumas. It includes: opportunities for social connection/coregulation (including on-line) craft projects walking For more many more tools and strategies visit Ilenenaomirusk.com   To learn more about the BrainFit program at Kemper Cognitive Wellness visit kemperwellness.com

During the second hour of the show Shane gets you caught up on everything you need to know from the world of sports, Shane talks with Maggie of the Blonde team about the charity baseball game taking place in Wichita on Saturday for Alzheimer and the guys prove once again that Shane's old and Marco's young... See omnystudio.com/listener for privacy information.

For full show notes, resources mentioned, and transcripts go to: www.drmindypelz.com/ep92/ To enroll in Dr. Mindy's Fasting membership go to: resetacademy.drmindypelz.com This episode is all about disconnection syndrome: the idea that the modern world has not only changed our brains but has disconnected us from each other. For us to thrive, we're going to have to reconnect ourselves to each other, to nature, and our own brains. Austin Perlmutter, M.D., is a board-certified internal medicine physician, New York Times bestselling author, educator and consultant. He received his medical degree from the University of Miami and completed his internal medicine residency at Oregon Health and Science University in Portland Oregon. His focus is on helping identify and resolve the biological basis for "stuckness" in the body and brain, especially around decision-making. He hosts the Get The STUCK OUT podcast and is a co-producer of the Alzheimer's, the Science of Prevention Docu-series. His writing is featured online on MedPage Today, Doximity, KevinMD, Medium, Psychology Today, MindBodyGreen, and DrPerlmutter.com, and his work connecting COVID-19 with immune-related depression appears in the peer-reviewed scientific literature. Please see our medical disclaimer. 

Brain health plays an important role in your overall health, especially when paired with exercise. Adam Ortman shares some of the research on brain health - including links to dementia and Alzheimers Disease and how he's bringing brain centered workouts to Cincinnati. Find more information here: https://www.activatebrainandbody.com/     If you're in need of a health coach, and you'd like to check out Team Fit With Me - Get 10% off month 1 of all packages, plans, and add on services using this link:  www.teamfitwithme.com/poundthis   Facebook Pound Pack Community: https://www.facebook.com/groups/1146750489151659 For personal training with me at Cincy 360 Fitness email: Info@Cincy360Fitness.com Find me on Instagram: https://www.instagram.com/youcanpoundthis/ Website: http://amandavalentinebites.com/

Richard Lui is a journalist and news anchor for MSNBC and NBC News. He was formerly at CNN Worldwide. Lui is also a columnist, contributing to publications including USA Today, Politico, The Seattle Times, Detroit Free Press, and San Francisco Chronicle. In 2020 Lui directed the documentary Skyblossom which profiles five families, each with a student providing care for a veteran parent or grandparent with disabilities. This where today's topic, selflessness, comes into play. Seven years ago, Richard walked into his supervisor's office, prepared to give up his dream job at NBC, having just learned of his father's Alzheimer's diagnosis. As in the documentary, Richard was compelled to care for his father. It turns out, there was a comprise to be reached with NBC. It also turns out that what Richard learned from that time in his life became the basis for his book ‘Enough About Me - The Unexpected Power of Selflessness'. We are going to get the benefit of that learning in our conversation today.

What are we doing right and what are we doing wrong when it comes to dealing with Alzheimer's Disease and other forms of dementia? And, what should we be doing in the future? Our guests on this episode, Daniel George and Peter Whitehouse, have a lot to say about that. Dr. George is a medical anthropologist and associate Professor at Penn State. Dr. Whitehouse is a professor of neurology at Case Western Reserve University and a professor of medicine at the University of Toronto. Together, they are the co-authors of the new book, "American Dementia: Brain Health in an Unhealthy Society".  ****** Thanks to our sponsors of this episode! --> Aurate: we love this modern, minimalist, and affordable jewerly! They rarely run sales, so we're honored that they are offering one to our listeners! Go to http://www.auratenewyork.com/nobodytoldme and use promo code 'nobodytoldme' to get 20% off with no minimum order. --> AirMedCare Network (AMCN): add inexpensive Fly-U-Home coverage to your AMCN membership so that if there's a medical emergency, you can make the call to be transported back to your local hospital—closer to your own doctor and family. Fly-U-Home takes care of absolutely everything from hospital A to hospital B. No bills. No paperwork. It's a smart way to reduce stress—and put control of your care in your hands. Sign up for Fly-U-Home today and receive up to a $100 eGift Card. by going to airmedcarenetwork.com/tellme and use offer code TELLME.  Learn more about your ad choices. Visit megaphone.fm/adchoices

And This Week In Wellness just 4 weeks highly processed, carb laden foods have been linked to inflammation, memory loss and Alzheimer’s whilst Omega 3's and DHA have been shown to reduce the effects, even without other dietary changes. https://www.sciencedaily.com/releases/2021/10/211014172753.htm https://www.sciencedirect.com/science/article/abs/pii/S0889159121005043?via%3Dihub This podcast is brought to you by my new Facebook community Healthy Lifestyle Choices Listen In The post TWIW 127: Refined carbohydrates harm your memory appeared first on The Wellness Couch.

Sal Di Stefano, author of “The Resistance Training Revolution,” discusses the latest science about how building muscle is the best weight-loss strategy and reviews new research about how muscle signals your body to burn fat directly. Support Healthy Hydration and Exercise Performance with this new Electrolyte Stix by MYOXCIENCE Nutrition: https://bit.ly/3uAWrV6 **Pre-Sale Discount Ends October, 31st 2021** Get Sal's New Book: https://amzn.to/3AMfhKb Video Version of this Show: https://bit.ly/3AUoT5S Time Stamps: 0:00 intro 03:10 Rigidly structured nutrition is not sustainable. 05:00 We take nutrition advice from people with extreme physiques. 07:02 We do not have a weight loss issue. We have a problem keeping weight off. 14:10 Resistance training is a superior form of exercise for fat loss, heart health, and insulin resistance. 14:50 Resistance training stopped the progression of beta amyloid plaques that cause Alzheimer's, according to an Australian study. 17:40 Resistance training is using resistance specifically to build strength and muscle. 19:00 Running is a skill that needs practice and instruction. 20:05 Resistance training is all about form and technique. 24:30 The calorie burn during exercise is not very important in cardio because your body prioritizes energy conservation and efficiency. 26:00 Roughly half of the weight you lose with cardio, is muscle. 27:01 Strength training creates a less efficient, faster metabolism. 29:32 Weight lost through resistance training is body fat. 30:30 All you need is two days a week of resistance training to bring strength, tone and a faster metabolism. 32:30 Muscle memory: Building muscle the first time may take a while. Losing that muscle is slow. Regaining it is much faster than the initial buildup. 44:20 Gross motor movement compound exercises are most effective for building muscle. 45:50 Your central nervous system controls how your muscles fire, your strength and stability. 48:10 Proprioception, knowing where you are in space, increases with resistance training. 51:00 Resistance training elicits immediate and long-term hormonal responses. 51:35 Resistance training is the only pro-tissue form of exercise. 53:35 Resistance training reliably increases androgen receptors in men and women. 55:55 Low testosterone increases cancer risk, increases risk of heart disease, increases Alzheimer's and dementia risk, decreases quality of life. 56:48 The average 25-year-old male today has the testosterone levels of the average 60-year-old in 1980. 57:00 A 20-year-old male today have the grip strength of a 60-year-old in 1980. 57:50 Grip strength can predict all-cause mortality better than any other single metric. 01:05:30 Pushing yourself to maximum performance is counter longevity. 01:07:00 A low protein diet generally reduces longevity. 01:09:55 Obese people have weaker bones, less muscle and more bodyfat. 01:10:30 What builds muscle, builds bone. 01:17:50 Resistance training is in the elderly improves cognitive function and hormone profiles.

Want to know more about about how the brain's different neurotransmitter systems aren't functioning properly in Alzheimer's disease and how hippocampal synaptic plasticity impairment contributes to Alzheimer's pathology? Join Glory for the latest updates on research about the mechanisms of synaptic transmission and plasticity that contribute to the Alzheimer's disease pathology. With this month's new papers, August 2021 gives us 12 publications that try to answer all of your questions on the synaptic aspects of AD! You're sure to get your own synapses firing by listening to this episode! Sections in this episode: Neurotransmitters and neuropeptides (3:01) Electrophysiological changes (10:08) Synaptic plasticity (12:28) New AD models (14:24) Cognition and memory (18:58)  -------------------------------------------------------------- You can find the numbered bibliography for this episode by clicking here, or the link below:https://drive.google.com/file/d/193a8sYAFrnvz6buueDNvoY2YSmDgV2n1/view?usp=sharingTo access the folder with all the bibliographies for 2021 so far, follow this link (it will be updated as we publish episodes and process bibliographies), or click the following link below:https://drive.google.com/drive/folders/1N1zx_itPkCDNYE1yFGZzQxDDR-NiRx3p?usp=sharingYou can also join our mailing list to receive a newsletter by filling this form. Or tweet at us: @AMiNDR_podcast  --------------------------------------------------------------Follow-up on social media for more updates!Facebook:  AMiNDR  Twitter: @AMiNDR_podcastInstagram: @AMiNDR.podcastYoutube: AMiNDR PodcastLinkedIn: AMiNDR PodcastEmail: amindrpodcast@gmail.com  -------------------------------------------------------------- Please help us by spreading the word about AMiNDR to your friends, colleagues, and networks! Another way you can help us reach more listeners who would benefit from the show is by leaving us a review on Apple Podcasts or wherever you listen to podcasts. It helps us a lot and we thank you in advance for leaving a review! Our team of volunteers works together to bring you every episode of AMiNDR. In particular, this episode was scripted and hosted by Glory Nasseri, edited by Ellen Koch, and reviewed by Anusha Kamesh. The bibliography was made by Lara Onbasi and the wordcloud was created by Sarah Louadi (www.wordart.com). Big thanks to the sorting team for sorting all the papers published in August 2021 into themes for our episodes: Jacques Ferreira, Ellen Koch, Nicole Corso, Kate Van Pelt, Christy Yu, and Dana Clausen. Also, props to our management team, which includes Sarah Louadi, Ellen Koch, Naila Kuhlmann, Elyn Rowe, Anusha Kamesh, and Jacques Ferreira, for keeping everything running smoothly.Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.   https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w   -------------------------------------------------------------- If you are interested in joining the team, send us your CV by email. We are specifically looking for help with sorting abstracts by topic, abstract summaries and hosting, audio editing, creating bibliographies, and outreach/marketing. However, if you are interested in helping in other ways, don't hesitate to apply anyways.  --------------------------------------------------------------*About AMiNDR: *  Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!" 

Situation: An Heiligabend kommt Eltern von Gisela zu Besuch. Personen: Gisela, Arthur, Mama, Papa, Frau Fischer Ort: Zu Hause Gisela: Schatz, wie weit bist du? Sie kommen gleich. Arthur: Ja ja, ich bin gleich fertig. Die letzte Kugel hänge ich hier auf. … fertig. Hast du schon den Tisch gedeckt? Gisela: Ach, jetzt ist alles so schön aufgeräumt und der Tisch gedeckt. Ich hab‘ extra noch ein paar frische Blumen in die weiße Vase gestellt. Du weißt, diese hässliche Vase, die ich von meiner Mama geschenkt bekommen habe. Arthur: Darüber freut sie sich bestimmt. Hast du schon die Gans gebraten? Gisela: Die ist noch im Backofen und in etwa 40 Minuten fertig. Ich sag‘ jetzt aber schon, dass es nächstes Weihnachten nur Würstchen mit Kartoffelsalat gibt. Dann habe ich keinen Stress mit dem Kochen. Arthur: Das klingt doch gut. Dann geht alles schnell. Gisela: Schatz, hör mir mal bitte zu. Du weißt doch, mein Vater ist krank und verwirrt. Er hat ja Alzheimer. Bitte kümmere dich um meinen Vater, sonst du weißt schon, was passieren wird. Erinnerst du dich noch ans Feuer im Keller? Arthur: Ja, da wollte er ein Lagerfeuer machen. Wenn ich nicht zufällig nach unten in den Keller gegangen wäre, wäre das komplette Haus abgebrannt. Gisela: Oh sie sind da. … Hallo, Mami. Mama: Gisela, die Tür klemmt! Gisela: Heben und drücken gleichzeitig, Mami. Gisela: Wie war die Reise? Mama: Ach, es wird immer schlimmer mit deinem Vater. Am Bahnhof wollte er mit dem Taxi … Gisela: Jetzt kommt erst mal rein. Mama: Oh, die Hundehütte sieht großartig aus. Das war aber wirklich nötig, denn Balu ist immer nass bei Regen. Gisela: Ja, das stimmt. Mama: Wolltet ihr das Haus nicht renovieren lassen? Gisela: Wir haben schon teilweise selber renoviert. Das ist ja viel Arbeit. Mama: Das macht aber bestimmt eine Malerfirma, oder? Gisela: Nein, Arthur ist ein guter Handwerker. Er macht das alles selbst. Alles geht ein bisschen langsamer aber … am Ende wird es immer gut. Papa: Wer sind Sie? Gisela: Ich bin deine Tochter Gisela. Kommt rein. Ich mach‘ euch einen schönen Kaffee. Papa: Ich muss mal … Mama: Ja, natürlich. Jetzt muss er mal ganz dringend auf die Toilette. Im Zug wollte er partout nicht. Gisela: Komm, Papi. Mama: Wo habt ihr denn diesen Baum gefunden? Beim Sperrmüll? Gisela: Gefällt er dir nicht? Mama: Nein. Arthur: Hallo. Mama: Hallo, Arthur. Arthur: Wie war die Reise? Du siehst so blass aus. Bist du müde? Mama: Ach, schrecklich, schrecklich. Gisela, wo bist du denn? Gisela: Hier. Mama: Was kommt heute auf den Tisch? Lass' mich raten: Gänsebraten mit Klößen und Rotkohl. Der Tisch ist aber noch nicht gedeckt? Gisela: Doch, doch. Wir haben den Tisch in der Küche vorbereitet. Mama: Na, gut. Arthur: Habt ihr Klaus verloren? Wo ist er denn? Gisela: Er wollte zur Toilette. Mama: Aber, die findet er doch nicht alleine. Gisela: Papa? ... Hallo Frau Fischer. Fr. Fischer: Hallo Frau Seese. Ihr Wagen hat gestern und vorgestern schon wieder in unserer Einfahrt gestanden. Das geht so nicht. Gisela: Da haben Sie natürlich völlig recht. Das geht so nicht. Ich werde mit Arthur reden, dass das nicht wieder vorkommt. Ich wünsche Ihnen alles Gute. Und frohe Weihnachten. Fr. Fischer: Ihnen auch frohe Weihnachten! Feiern Sie dieses Jahr gar nicht mit Ihren Kindern? Gisela: Doch, doch. Sie sind schon unterwegs. Wir feiern alle zusammen, meine drei Kinder und meine Eltern. Fr. Fischer: Na, das wird ja wohl kein ruhiger Abend! Dann wünsche ich Ihnen noch ein schönes Fest und viel Freude …

SPECIAL OFFERS FOR BULLETPROOF RADIO LISTENERSMeasure Brain Function: Learn more and get a special discounted package at https://wavimed.com/, use code DAVEWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Non-Tobacco Nicotine Alternative: https://lucy.co, use code DAVE20 to get 20% off your first order of pouches, gums, or lozengesRevitalize Your Mitochondria: https://www.timelinenutrition.com, use code ASPREY10 to get 10% off the plan of your choiceEat Good Keto Bread: https://www.uprisingfood.com/DAVE, use code DAVE to get $10 off the starter bundle. That includes two superfood cubes and a four pack of freedom chips!IN THIS EPISODE OF BULLETPROOF RADIO... I talked to the co-founder of WAVi at the 7th Annual Biohacking Conference in Orlando, Florida. Physicist David Oakley created a device that's used to directly measure brain function and gives you a 360-degree assessment of your brain performance.WAVi is an all-in-one measurement platform. Users get objective information about brain function through EEG, visual ERP, auditory ERP, heart rate variability (HRV), Trail Making, standard assessments and more. This full FDA-regulated Class II device measures biomarkers of your brain with detail and precision in under 15 minutes.“People measure their weight every day, right?” David says. “Step on the scale, “Where am I at today?” So, we should be measuring our brains regularly. Someday there will be WAVi in doctors' offices and you'll check your brain like you check your weight.”For an introduction to WAVi, listen to Bulletproof Radio episode #619: Your Brain Voltage: Measure It, Raise It, Control It. In this interview, David and I go really deep into the science behind WAVi's development. We get into physics, neuroscience, brain data, scientific inquiry and what's exciting about the future of brain performance research. David comes from a long family line of inventors and creators. His own career as a physicist includes research and teaching at universities. He was also a researcher at the Los Alamos National Laboratory and has analyzed data within neutrino astrophysics, a branch of astronomy that observes astronomical objects with neutrino detectors in special observatories.He has published research and articles in the areas of physics, medicine, and art. At mid-life he turned to brain data and created WAVi: a mix of art, science, commerce, and public service.He made the move to study the brain when he met a fellow scientist David B. Jaffe. “He started showing all the [brain] patterns, and I thought, “This is beautiful,” David says. “It's beautiful waves. You can do a lot with it. You can help people. It's about the same as physics, though. It's the same, just voltage versus time series data.”David's now exploring multiple brain topics, including concussions, Alzheimer's, Dementia, and mental health.You'll also find out why P300 continues to be an important signature of cognitive processes. It's a 300 millisecond time frame that measures brain activity. This includes attention, working memory and dysfunction in neurologic and mental disorders. Ongoing research sees it as a potential genetic marker of mental disorders.“As you age this performance drops and the speed drops,” David explains.And then there's voltage activity that's happening in the brain. And if you can assess and measure what's going on in your brain, you can do something about it.So, this is a really big thing. And I want you guys to think about this. Right now you might be saying, "I'm not a brain scientist, I'm just listening to this." But there's, how fast does the brain respond? And how strongly does the brain respond? Because those are different things. And the reason my brain does what it does, I would say is clearly nutrition and mitochondrial enhancement and supplements and all that kind of stuff.It's a fascinating time to be upgrading your brain! “So, 10 years from now, the happy path is that with the brain scan, the artificial intelligence will know you and know what you need to optimize your brain,” David says. “There won't be a question of, in the ideal world, it's not a question of your brain is slowing down. It will know you on day one and say, “This is what you need to do. As long as you stay with this program, you're going to have an optimized brain. It's not going to slow.” That's my 10-year future.”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What if the key to a healthier brain is as simple as getting up out of your chair?Quick Take is a weekly dose of ideas and insights delivered in short form.Today's episode features neurosurgeon Dr. Sanjay Gupta. Listen to the full episode https://www.aspenideas.org/podcasts/building-brain-health-at-any-ageFollow us on instagram.com/aspenideas Follow us on facebook.com/aspenideasFollow us on twitter.com/aspenideas

Brand new episode! Toasted Marshmallow Adventures Studio proudly presents Episode #3 from LOVE YOU, MOM. AN ALZHEIMER'S STORY. “Changes” discusses the troubling changes my Mom experienced cognitively, her fear and depression and the doctors appointment that changed our lives forever. Thank you so much for listening!❤ Age of Radio: https://www.ageofradio.org/toastedmarshmallow/ Instagram: https://www.instagram.com/toastedmarshmallowadventures1/ Facebook: https://m.facebook.com/#!/ToastedMarshmallowAdventures/?ref=bookmarks Website: https://toastedmarshmallowadventures.com/ Email: gettoasted@toastedmarshmallowadventures.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr Gabriel Niles, MD has travelled many roads in his search for the ideal model of healing and flourishing. Prior to his training as a Medical Doctor at USC School of Medicine, he studied Traditional Chinese Medicine in Shanghai, China. He has organized and led multiple Circle of Healers retreats with the American Medical Student Association as a medical student, seeking to integrate the wisdom of healing traditions with modern medical science. In recent years, Dr Niles has been integrating the insights and benefits of Functional Medicine into his medical practice while remaining committed to keeping medical care affordable for his patients.  For this podcast, I caught up with Gabe after the Ancestral Health Symposium in Los Angeles to discuss his integration of Functional Medicine into a mainstream bill-to-insurance medical practice. We talk about areas where his approach differs from that of other family physicians, including his favouring of lifestyle changes over-reliance on pharmaceuticals. He also explains why he has continued working within the conventional medical system, despite rejecting the big-pharma controlled dis-ease model of medical “care”. Here's the outline of this interview with Gabriel Niles: [00:00:27] Gabriel's background and interest in medicine and health. [00:02:33] Evan Hirsch, MD; Podcast: How to Fix Your Fatigue. [00:03:01] Institute for Functional Medicine's AFMCP Training. [00:03:15] Studying Chinese medicine. [00:09:58] Service in the US Navy. [00:13:30] Dr. Kirk Parsley; Podcasts: 1. How to Get Perfect Sleep with Dr. Kirk Parsley, MD; 2. Sleep To Win: How Navy SEALs and Other High Performers Stay on Top. [00:14:27] Saying no to Big Pharma; The problem with statins. [00:17:14] Ancestral Health Symposium. [00:20:20] James Nestor; Book: Breath: The New Science of a Lost Art; Podcast: How to Fix Your Breathing to Improve Your Health. [00:21:06] Todd Becker; Podcast: Getting Stronger; AHS Talk: Desirable Difficulties: Using Hormesis to Learn More Effectively - Todd Becker (AHS21). [00:23:20] Mickey Trescott; Podcast: Autoimmune recovery with Mickey Trescott. [00:26:22] Book: The End of Alzheimer's, by Dale Bredesen. [00:28:41] Medical problems faced by knowledge workers. [00:31:13] International Society for Environmentally Acquired Illness (ISEAI). [00:34:37] Books: It Starts with Food and The Whole30, by Melissa Hartwig Urban and Dallas Hartwig. [00:36:39] Paul Saladino: The Carnivore Code; Podcast: Fundamental Health Podcast. [00:40:23] Book: Natural Causes by Barbara Ehrenreich. [00:42:56] Why Gabriel continues to bill insurance. [00:44:34] Podcast: The Community Cure: Transforming Health Outcomes Together, with James Maskell. Book: The Community Cure. [00:45:31] Evan Hirsch's Virtual MD course. [00:47:48] Work with Gabriel Niles in Los Angeles, CA.

Louie Schwartzberg is an award-winning cinematographer, director and producer who has spent his notable career providing breathtaking imagery using his time-lapse, high-speed and macro cinematography techniques. Schwartzberg is a visual artist who breaks barriers, connects with audiences, and tells stories that celebrate life and reveal the mysteries and wisdom of nature, people, and places. He has made many meaningful films, his recent production is called Fantastic Funghi, which explores the world of mushrooms and mycelium and illustrates how this fascinating organism can provide sustainable solutions to some of the world's greatest problems, treating cancer, Alzheimer's and PTSD, saving the bees, cleaning the atmosphere, and shifting consciousness. Awakening us to seeing in full sight that we live in a LIVING UNIVERSE. --- Support this podcast: https://anchor.fm/julian-guderley/support

In Episode 44,  Don and I had a candid conversation with Jennifer Fink -   Founder and Host of Fading Memories Podcast - about a topic that doesn't  seem to get as much attention as it should. Personal hygiene and our loved ones. As Alzheimer's progresses, poor hygiene can become an issue: people living with dementia (PLWD) often refuse to bathe and even change their clothes.  It can even lead to medical problem such as urinary tract infections. Because Alzheimer's causes a slow decline of cognitive functions, a PLWD will begin to get confused about seemingly simple things, like how to wash their hair.  A PLWD may be overwhelmed and confused by all the products on the bathroom counter, perhaps mistaking a tube of lotion for toothpaste. Sometimes they don't recognize their loved ones or even themselves, so the images they see in the mirror may be confused as strangers!Sensory perception, especially vision, touch and smell, also changes. This can make a tub of water seem scary as depth perception changes.  The water spray from the shower can feel like sharp needles.  A smelly shirt may be more comforting than a freshly laundered – but unfamiliar – replacement. Room or water temperature may feel different to the PLWD than it does to us. Jennifer shares some of the best tips for overcoming the challenges associated with PLWD's and their personal hygiene.  Jennifer spent the first half of her adult life as a portrait photographer, retired from in early 2020. Listening to podcasts became a favorite way to learn new things while walking the dogsor doing household chores. After the death of her father in March 2017, dealing with and caring for her Mother became a much bigger part of her life. Looking to her favorite media in search of answers and not finding what she was looking for, Jennifer decided she would create a supportive podcast that caregivers of Alzheimer's patients need and deserve. Jennifer is the daughter, grand daughter & great grand daughter of women who suffered from Alzheimer's or other cognitive impairment. Looking for answers on how not to become the fourth generation with this problem  has led her on this interesting journey with her new passion, podcasting.Connect with Jennifer: FACEBOOK TWITTER INSTAGRAM LINKEDIN APPLE PODCAST SPOTIFYSupport the show (https://www.patreon.com/preview/3feccac8decf451cbee818066461f7c1)

Make your health an act of rebellion. Join The Healthy Rebellion Please Subscribe and Review: Apple Podcasts | RSS Submit your questions for the podcast here News topic du jour: https://www.nytimes.com/2021/10/12/health/aspirin-heart-attack-stroke.html 1. Peptide uptake orally [12:50] Andreas says: Dear both. First of all thank you both for all that you do. I am very grateful for you weekly courage, «sticking your neck out there», sharing your take on life while crushing main stream «dogma”. Love it, great job – please keep it up. Now, could you please help me understand how all the so called beneficial peptides in animal foods ends up in the human body to deliver any biological function? The human digestion system is very good at breaking down peptide sequences long before they reach their  destination to give any biological function (both spontaneously, non-enzymatically, like stomach acid, and enzymatically by peptidase etc.). Now days, I am experimenting using my chicken eggs as a “delivery vessel” by which I deliver non palatable but highly nutrient dense organ foods to my family indirectly by actively changing the egg nutrient profile(or so I think). The chickens free range and get plenty of sunshine in the summer, eat bugs, greens, wild herbs and berries, while I occasionally feed them organ meats(primarily beef liver and heart), beef tallow etc. They get no plant oils, soy and so on. They love the organ meat and look/act very healthy. I know the fatty acid profile of the eggs will change to a higher percent of for example steric acid (based on research literature), but not sure about the other vitamins, minerals and peptides from their diet actually ends up in the eggs – and so is passed on to my wife and kids. I have no problems eating meats like liver and heart, but they will not touch it, let alone eat it. But they absolutely LOVE my dishes that I preparer from those eggs (like carnivore waffles etc.). But if humans (or chickens) do not absorb many of these nutrients, peptides in a biological active form and increase the nutritional profile of the eggs, well, then the story ends there. A little bit like some expensive skin care products that my wife uses, that proclaim the price I justified with added water soluble vitamins that should be so healthy, but will not ba absorbed unless you eat the damn thing.. Best, Andreas 2. Non-carb processed food, issues? [18:10] Mike says: Hi, can't explain how important you guys have been in my life over the past 12ish years. I've listened to EVERYTHING and implemented SOME (realistically a lot, although I don't really have any health / nutrition / digestive issues so it's more of a favorite-subject/interest of mine than a dire need to make sweeping changes sort of thing). Question: I know ‘processed' foods are worse for us for a number of reasons and that there are different levels of processing (highly processed factory food, steak vs ground meat, blending mainly unprocessed foods to make a smoothie, etc) but my question is, are these processed foods ever better for us than the unprocessed? …or maybe equivalent, mainly when it comes to processed fat/protein. I've wondered for a while, if a quality liverwurst, from USwellness for example, might be an ideal food, despite the baggage it carries along with it ‘processed meat'. THE DEVIL! But let's be realistic here. My understanding of this product is that it's a nose to tail tube of goodness, from a healthy animal, all slapped together, with some spices. All good right? Is there any benefit or detriment to this sort of thing? Does the protein/fat being digested more quickly than if I chewed the component parts individually, really matter?? I know processed sugar becomes a blood sugar issue, but does processed fat/protein have a similar corollary?? Thanks! Side note, I know you always say chew your food and I think this mostly refers to people who have weight control issues and need the chewing/eating/fullness slowdown to moderate their intake. Clearly this is probably one way to answer the above question but is there anything else?? PS: I've often thought of getting a tattoo of the fraction 1/6 somewhere, to signify I was one of six listeners, with the added benefit that nobody else would know why the hell I had it!! Thanks… hopefully this shoots to the healthy rebellion e-mail… couldn't figure out how to ask a question to the new poddy. I joined the rebellion for a month last year and it's great and all but I just realllllllly don't like social media. (It's not you it's me ) 3. Lifting With a Slipped Disk [29:06] Trystan says: Robb and Nicki, Love the podcast! I'll make this short - my wife has had an operation on her back due to a slipped disk, but she's curious to start lifting. What do you guys think? I'm no expert, however it does seem a bit risky. That being said she knows her body and what her back can take more than anyone... Would love to hear your advice on whether lifting with slipped disks could be beneficial or downright dangerous. All the best, and keep up the good work. 4. Cluster Dextrin [40:43] Jackson says: I would love to hear your opinion on this! Thanks 5. Nicotine Adverse Effects? [42:45] Garrett says: Hi Robb & Nikki, 'Been around since the Paleo Solution podcast days, so while I'm not an OG-6 listener, OG-20 is not out of the question. I heard a Q&A episode a while back where a listener asked about the caffeine-nicotine protocol you suggested for special forces, or anyone working odd hours / graveyard shifts to stay moderately alert while still being able to unwind at the end of the day. In a similar vein, on a recent Huberman Lab episode he mentioned the potential benefits of Nicotine in treating Alzheimer's disease. I believe it is universally agreed upon Nicotine is a nootropic / cognitive enhancer. Now to my question - I'm Swedish, and we have quite the 'snus-culture' over there, our spin of dry snuff (tobacco pouches, but without the spitting you see with American dip). I've gravitated towards this as an alternative to drinking, and I should note I've moved to the tobacco free versions containing only nicotine (Zyn is a brand that is making it's ways in the U.S.). However, one can't really drink on the job, whereas the only bad time for some snus is while eating and sleeping, leaving about 16 hours of consumption throughout the day. Is there to your knowledge a 'healthy' range to stay within? In the U.S. they are sold in 3 and 6mg pouches, however the 'good stuff' I can get in Sweden goes all the way up to 20mg. According to a quick Google search, only 10-20% of the content is actually absorbed, meaning the dose "per hit" is up to 4mg. I could be on the high end consuming shy of 50mg per day some days. I've gladly taken in your and Andrew's notes as a compelling argument that I'm functioning better cognitively while staving off Alzheimer's disease, but I have a good feeling there's another side of this story I should heavily consider as for all I know I'm doing damage equivalent to smoking a pack a day, just wrapped in different packaging with different side effects. Appreciate all you do to keep us informed and entertained. -Garrett Sponsor: The Healthy Rebellion Radio is sponsored by our electrolyte company, LMNT. Proper hydration is more than just drinking water. You need electrolytes too! Check out The Healthy Rebellion Radio sponsor LMNT for grab-and-go electrolyte packets to keep you at your peak! They give you all the electrolytes want, none of the stuff you don't. Click here to get your LMNT electrolytes Transcript: You can find the transcript at the blog page for this episode https://robbwolf.com/2021/10/15/is-ground-meat-processed-food-nicotine-adverse-effects-lifting-with-slipped-disk-thrr091/

En este episodio Frank explica de qué manera se puede prevenir el Alzheimer modificando la dieta y ejercitándose adecuadamente. Para obtener la ayuda de un Consultor Certificado en Metabolismo hable al 1-888-348-7352 o visítenos online en https://us.naturalslim.com En Puerto Rico hable 1-787-763-2527 o visítenos en http://www.naturalslimstore.com En Europa +3120-2296-300 o visítenos en https://www.naturalslim.eu En México hable al (55) 5256-1368 En República Dominicana envíe mensaje por Whatapps al 1-787-249-3198 En Panamá +507 396-6000 En Costa Rica (506)2430-2010 En Colombia al (57-1) 7020928 Subscríbete a Unimetab aquí y permite que Frank te lleve de la mano paso a paso: https://www.unimetab.com/ Subscríbete a MetabolismoTV en Messenger para acceso a educación exclusiva por Frank en el tema del metabolismo: https://www.messenger.com/t/Metabolis... Para ordenar el libro en uno de los países listados abajo contacte a través de https://www.naturalslim.com a su distribuidor local quien le ayudará a obtenerlo. Descubre tu metabolismo junto con el autor Frank Suárez, especialista en Obesidad y Metabolismo, y escritor del Best-Seller "El Poder del Metabolismo", para que puedas adelgazar y mejorar tu salud. Sigue a Frank y MetabolismoTV en Facebook aquí: https://www.facebook.com/MetabolismoTV/ Envíale un mensaje a Frank y al equipo de MetabolismoTV aquí: https://www.messenger.com/t/Metabolis... Acceso a Libros Digitales con Membresia a www.MetabolismoVIP.com La información que se brinda en MetabolismoTV® tiene un propósito puramente educacional. No pretendemos diagnosticar, curar o de alguna otra forma sustituir la ayuda profesional de su médico, nutricionista, dietista u otro profesional de la salud cualificado. Usted siempre debe consultar con su médico antes de empezar a hacer cualquier cambio en su dieta muy en especial si está recibiendo tratamiento médico o utiliza medicamentos recetados.

Kayleigh Williamson made history in 2017, when she became the first person with Down syndrome to run in - and complete - the Austin Half Marathon.  Since then she's finished 12 more half marathons, numerous races at other distances, and is training for her first marathon in 2022. She's written a children's book, It's Cool To Be Me, dedicated to people with Alzheimer's, which her late grandmother suffered from and which often occurs in people with Down syndrome.  Her running journey is inspiring proof of what grit and heart can accomplish.   “I had taken her to a doctor at 215 pounds. He looked at her and he told me,‘this, it's not gonna end well.'” Kayleigh was in her early 20s when her grandmother had her second stroke and soon after was diagnosed with Alzheimer's.  Her mother, Sandy, began researching the disease and discovered that the chance of somebody with Down syndrome developing Alzheimer's is “astronomically higher”  than it is for other people.  Kayleigh consumed a lot of fast food, processed food, and soda, and weighed 215 pounds. She had developed autoimmune disorders, including Graves' disease, and Sandy knew that she had to do something to help her daughter. “I expected some type of rejection. And the running community, we got total acceptance and 80 pounds came off of her body and every one of her autoimmune disorders went into remission. And today I see how healthy she is.” Sandy initially feared that Kayleigh wouldn't be accepted by the running community, but they embraced her.  And even though she began running because of Sandy's encouragement, it's her own commitment that takes Kayleigh to the finish line.  “I tell her she can stop if she needs to stop,” Sandy says. “ She never does. And that's the part that's kind of humbling to me whether we're training or we're in the middle of a race because she's got this determination that she just doesn't stop.” “You have to get to the point you don't care what the rest of the world thinks.”  The opinion of others bothered Sandy more than it did Kayleigh.  She remembers a race where they were in last place.  She grabbed Kayleigh's hand to get her to run faster, and Kayleigh jerked her hand back.  At that point, Sandy realized, “It's more important for her to finish the race than what anyone else thinks about where we are in the race. And I think that's kind of the same for life.” “If you pick up your toys and go home, you don't influence change.” That isn't to say that disregarding others' opinions is easy.  Sandy recalls a race where people were openly staring and taking pictures, and she resolved that they would never go back there.  But then she realized that the situation would never improve if they just walked away, so, she says, “we have specifically decided that we're going back and we're doing those races over again until we impact that change.” “I think anytime you're told that your child is uniquely different in any way, you feel this need to protect them to the point that you think you're fixing it. And really it was the realization that she didn't need fixing.” When Kayleigh was born, Sandy was told that she should put her in an institution.  Now she's proud that her daughter can stand on her own two feet.  She's realized that “she doesn't need me protecting her, a lot of times she needs me to get out of the way.”  Sandy raised Kayleigh to give everything her best shot.  She's done that, and succeeded. “Don't let somebody else tell you what you can and cannot do.  Get out there and try it, and if the first time you try it and you don't succeed, but you know in your heart of hearts you can still do it, get up there and do it again as many times as you need to get back up.” resources: Kayleigh's Instagram Kayleigh's Facebook Video of Kayleigh at the Austin Half Marathon It's Cool To Be Me Thank you to Tracksmith, InsideTracker, and Beam for sponsoring this episode. Tracksmith is a Boston based company that truly cares about the quality of their running clothes. Running can be demanding on our clothes; they definitely go through wear and tear to where we may be purchasing new clothes constantly. Tracksmith designers work with the finest materials and keep you in mind as a runner, with spots for your keys, phone, and fuel. You can go here to check out my favorites! Click here and enter code TINA15 to get $15 of your purchase of $75 or more. Have you not been feeling yourself lately? Gone down a lot of avenues but haven't really found clear solutions? That is where InsideTracker can come in for you.  I have trusted this company for years to show me where I may be lacking and if I need a few tweaks here and there. I count on InsideTracker to help me decipher the science behind it all. Go here to get 25% off as a special for Running for Real listeners on their ENTIRE store. A new product that I've been trying out is Beam; they help athletes with balance, performance, and recovery. I've used “elevate energy” and “elevate balance” and the flavors were great. I felt that the hydrating electrolyte energy powder, formulated with beetroot, green coffee bean, and citrulline, really helped me and I know they will help you too. Go here and use code TINA for 15% off your order or 20% off a subscription. Thanks for listening! We know there are so many podcasts you could listen to, and we are honored you have chosen Running For Real.  If you appreciate the work that we do, here are a few things you can do to support us: Take a screenshot of the episode, and share it with your friends, family, and community on social media, especially if you feel that the topic will resonate with them.  Be sure to tag us on Twitter, Facebook, Instagram If you are struggling through something a guest mentions, chances are others are too, and you will help them feel less alone.  Leave an honest review on iTunes or your favorite podcast player. Your ratings and reviews will really help us grow and reach new people. Not sure how to leave a review or subscribe?  You can find out here. "Thank you" to Kayleigh and Sandy.  We look forward to hearing your thoughts on the show.

Una de las mayores preocupaciones del mundo moderno es el del aumento contínuo de casos de demencia senil, en particular del mal de Alzheimer. El entendimiento a nivel molecular de esta enfermedad y algunos estudios estadísticos revelan nuevas posibilidades prácticas para crear tratamientos paliativos cada vez más efectivos. Este entendimiento comienza a dibujar la posibilidad de crear preventivos efectivos e incluso tratamientos curativos. Esto a su vez podría ayudar a controlar e incluso eventualmente a eliminar por completo a las enfermedades neurodegenerativas más comunes. Gracias por sus comentarios, apoyo y suscripción. Escuche/descargue (MP3) 21/10/14 El Ocaso del Alzheimer. Gracias por su apoyo a El Explicador en Patreon https://www.patreon.com/elexplicador_enriqueganem y PayPal elexplicadorpatrocinio@gmail.com, https://soundcloud.com/el-explicador, https://open.spotify.com/show/01PwWfs1wV9JrXWGQ2MrbY, https://podcasts.apple.com/mx/podcast/el-explicador-sitio-oficial/id1562019070 y https://youtube.com/c/ElExplicadorSitioOficial. Gracias. Lo invitamos a suscribirse a estos canales para recibir avisos de nuevas publicaciones y a visitar nuestra página http://www.elexplicador.net. En el TÍTULO de nuestros trabajos aparece en primer lugar la fecha año/mes/día de publicación, lo que facilita su consulta cronológica. Siempre leemos sus comentarios, muchas veces no tenemos tiempo para reponder a cada uno personalmente pero son leídos y tomados en cuenta. Este es un espacio de divulgación científica en el que nos interesa informar de forma clara y amena, que le invite a Ud. a investigar sobre los temas tratados y Ud. forme su propia opinión. Serán borrados los comentarios que promuevan la desinformación, charlatanería, odio, bullying, violencia verbal o incluyan enlaces a páginas que no sean de revistas científicas arbitradas, sean ofensivos hacia cualquier persona o promuevan alguna tendencia política ya sea en el comentario o en la fotografía de perfil. Aclaramos que no somos apolíticos, nos reservamos el derecho de no expresar nuestra opinión política, este es un canal cuya finalidad es la divulgación científica. Gracias por su preferencia. AVISO: En la área inferior de nuestros vídeos aparece un recuadro de la Secretaría de Salud con una liga, queremos aclarar que estos letreros aparecen sin nuestro conocimiento o notificación previa alguna y que no nos están patrocinando en forma alguna. ACLARACIÓN IMPORTANTE: El virus SARS- CoV-2 y la enfermedad COVID-19 SI EXISTEN, SON REALES. Le sugerimos que siga atentamente las recomendaciones de la Secretaría de Salud: higiene, mascarilla o tapaboca cuando salga de su domicilio y sobre todo quédese en casa cuando no sea indispensable salir.

Have you ever seen those videos online where someone hears a song, and they're instantly transported back to a moment? It could be someone with Alzheimers or Dementia, or with a brain injury or trauma that language can't reach, but music can. Maybe you've known someone with autism, who is non verbal but can communicate with song.   It's called music therapy, and the science behind it, is incredible. Usually the Take 5 is with a muso, or person in the public eye. But I wanted to step into another realm, and get inside the brain of a registered music therapist. Chanelle Henderson is just that. She works with a really broad array of people too, from elderly clients to little kids and preterm babies and their parents. And across five songs, she invites you into this world and tells you the stories of some incredible breakthroughs. From three chord simplicity, to bonding with babies, and the music that takes us back instantly as a sensory memory, this is a beautiful conversation about the scientific and emotional power of song.   You Are My Sunshine - Johnny Cash Stop - Spice Girls Raining on the Rock - Warren H Williams Song for Sammy - Missy Higgins Sitting On The Dock of the Bay – Otis Redding

If there's one thing most of us fear, it's cognitive decline and Alzheimer's disease. So what can we do to prevent it? In today's episode, Matt Tullman speaks to Dr. Dean Sherzai, a behavioral neuroscientist, on the lifestyle changes you can make to support long-term brain health and help prevent chronic cognitive issues.

Marnie Chesterton hears of a simple test for the earliest signs of Alzheimer's disease. She finds out about UK scientists using robots to map radiation at Chernobyl, and talks to Merlin Sheldrake about fungi. Roland Pease travels to Bath University to meet scientists who may have developed a way to diagnose Alzheimer's in the earliest stages of the disease. Dr George Stothart, has led the team in the development of this simple 2 minute test. Prof Thomas Scott of Bristol University and team develop robotic techniques to scan areas of high radiation that would otherwise be unsafe for humans to enter. Their rolling, quadruped or even flying robots have recently been deployed in and around the reactor building at the Chernobyl disaster site. Authorities there have recently been licensed to begin disassembling remains inside the vast concrete shield, but as they do so, areas of intense radiation are likely to shift from day to day. Being able to map these changes in 3D at the end of each working shift should enable workers to avoid the areas of biggest danger. Dr Merlin Sheldrake is one of the nominees for this years Royal Society Insight Investment Book Prize. "Entangled Life - How Fungi Make Our Worlds, Change Our Minds, & Shape Our Futures" is a rich tale of interconnectedness and subtle intrusion and extrusion between different living things, and particularly fungi's huge influence on human existence, from beer, bread and psychedelia to the whole history of life on earth. Presented by Marnie Chesterton Produced by Alex Mansfield Made in Association with The Open University

For the last six months, Kristin's spent her time balancing her work life and being a mom. But finally, she's ready to go on her first girls trip. She'll tell us all about her excitement, but first, we need to talk to Bert.Bert just found out that his aunt is suffering from Alzheimer's, just like his mom. It was shocking news, but what was more shocking is that she ended up in the same facility as his mom.  See acast.com/privacy for privacy and opt-out information. Become a member at https://plus.acast.com/s/the-bert-show.

A recent study of nearly 1,800 participants from the UK Biobank found that three dietary elements — cheese, wine, and lamb — may improve long-term cognitive outcomes in aging adults. Dr. Auriel Willette, assistant professor of food science and human nutrition at Iowa State University, joins the podcast to discuss these new findings linking diet and cognitive changes. In November 2020, Willette published a study in the Journal of Alzheimer's Disease titled “Genetic Factors of Alzheimer's Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study,” where he and his team studied the effects of particular foods on a person's brain health over time. As well as the findings surrounding cheese, wine, and lamb, they found that limiting salt intake was good for the brain, especially for those at risk for Alzheimer's disease. Discussing the field of nutritional research, his prior work studying diet and brain health, and how these findings impact other recommended diets, Willette provides insight into how our current diets can impact our health and cognitive abilities later in life, allowing us to make better choices for the future. Guest: Auriel Willette, PhD, associate professor of food science and human nutrition, Iowa State University. Episode topics 1:34 - What sparked your interest in studying the effects of nutrition on the brain and on cognition? 4:41 - What prompted you to broaden your study to focus on overall diet and whole foods? 8:29 - Can you tell us about your prior research? 12:46 - Can you tell us a bit about the study and what you discovered? 19:48 - What do you think the mechanism is that allows cheese and alcohol to be beneficial for people's brain health? 24:28 - How do you reconcile these findings, especially those surrounding cheese, with diets like the MIND diet? 28:38 - What dietary changes have you made in your own life that you might recommend for protecting your brain health? Show Notes Find out more about Dr. Willette by reading his bio from Iowa State University. Learn more about Dr. Willette's study at this article by Iowa State University. Read the full study, “Genetic Factors of Alzheimer's Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study.” Find us Online - Dementia Matters Website | ADRC Facebook | ADRC Twitter

Ali Abedi is Professor of Electrical and Computer Engineering and Cooperating Professor of Computing and Information Sciences, an Associate Vice President for Research, and Director of Center for Undergraduate Research (CUGR) at the University of Maine. His work relies heavily on a multi-disciplinary approach that is focused on engineering with a strong recognition of the foundation provided by physics and math. ~~~~~~The 2022 Maine Science Festival Call for Ideas is open (https://www.mainesciencefestival.org/call-for-ideas) until November 19, 2021.Tickets are now on sale for the 2022 Headliner: The Warming Sea - an exploration of Hope in the face of the climate crisis. (thewarmingsea.me) - March 19, 2022, 7pm, Collins Center for the Arts.~~~~~~The Maine Science Podcast is a production of the Maine Science Festival. It was recorded at Discovery Studios, at the Maine Discovery Museum, in Bangor, ME. Edited and produced by Kate Dickerson; production support by Maranda Bouchard and social media support from Next Media. The Discover Maine theme was composed and performed by Nick Parker.  If you want to support the Maine Science Podcast and/or the Maine Science Festival, you can do so at our website mainesciencefestival.org either at our donation page OR by getting some MSF merchandise through our online store.  Find us online:Website - Maine Science FestivalMaine Science Festival on social media: Facebook    Twitter     InstagramMaine Science Podcast on social media: Facebook    Twitter     InstagramMaine Science Festival Store - https://bit.ly/MSF-storecontact us: podcast@mainesciencefestival.org© 2021 Maine Science Festival

Henrietta Lacks died in 1951 from a virulent cervical cancer. A sample of those cancer cells was taken at the time and the way they behave has changed medical science forever – contributing to everything from the polio vaccine to drugs for Parkinson’s and Alzheimer’s disease. As the WHO give a posthumous award Claudia discusses how the Henrietta Lacks legacy raises issues of global health equity. Plus with a Malaria Vaccine given a historic green light by the WHO to protect children in Africa, what are the distribution difficulties in countries which carry the greatest burden of disease? And what’s behind the low rate of Covid-19 vaccinations in Taiwan? We hear from one resident about why she’s chosen to have a home-grown Medigen vaccine which hasn’t yet completed all its clinical trials – and another who wants to wait for an alternative. Scientists say that trials about to start in Paraguay should show whether it stimulates enough immunity to protect people in the way the AstraZeneca vaccine does. Presenter: Claudia Hammond Producer: Erika Wright (Picture: Henrietta Lacks, after whom HeLa cells are named, standing outside her home in Baltimore, USA. Photo credit: Getty Images.)

Cancer. Alzheimer's. Heart disease. Diabetes. Infertility. While these prevalent and dreaded diseases are caused by multiple factors, my guest says they also all share a common thread: a ubiquitous and too-little-understood condition called insulin resistance.His name is Dr. Benjamin Bikman and he's a professor of biology and physiology, an expert in obesity and metabolic disorders, and the author of Why We Get Sick: The Hidden Epidemic at the Root of Most Chronic Disease — and How to Fight It. Ben begins our conversation by explaining insulin's role in the body, how it goes awry when it comes to Type I and II diabetes, and how giving Type II diabetics insulin to treat their disease actually makes them “fatter and sicker, and kills them faster.” We then turn to the fact that even if you don't have diabetes, you very likely still have insulin resistance (something helpful to keep in mind during this conversation is that "insulin resistance" is bad and "insulin sensitivity" is good), and the condition's three primary causes. Benjamin then unpacks how insulin resistance correlates with cancer, obesity, cardiovascular disease, and reproductive health problems, including the fact that erectile dysfunction isn't a function of low testosterone, but insulin resistance. We then talk about the role of insulin resistance in someone's susceptibility to COVID-19. We end our conversation with the four pillars of reversing insulin resistance, including the role of diet and physical activity, and how these lifestyle changes can work to help relatively healthy people get healthier, all the way up to allowing diabetics to get off their medication.I can't tell you how motivating this conversation was for me to start a habit of walking more during the day, as well as after dinner. I bet it will have the same effect on you.Resources Related to the PodcastInsulin resistanceConnection between high blood pressure and insulin resistanceErectile dysfunction and insulin resistanceConnection between cancer and insulin resistanceCOVID-19 severity and insulin resistanceAoM's series on testosteroneAoM's fitness articlesAoM's article on the benefits of cold showersAoM podcast on intermittent fastingAoM article on intermittent fastingHLTHCode (We're not affiliated with this company and they're not a sponsor, but we tried it, and love it, and have been consuming it daily.)Connect With Benjamin BikmanBenjamin's lab websiteBenjamin on Instagram