Progressive, neurodegenerative disease characterized by memory loss
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Content Note: This episode contains emotional discussion about death, hospice care, and Alzheimer's, which may be difficult for some listeners. In this deeply personal episode, Bret steps in to host. He candidly shares the story of his father Bob's final days. Bob was a beloved high school football coach known simply as "Coach." Bret describes the emotional experience of rushing to California, sitting with his dad during hospice care, and the meaningful moments that unfolded in the hours leading up to his passing. Through stories about family, love, Alzheimer's, and what truly matters at the end of life, this episode becomes a raw and heartfelt reflection on grief, legacy, and the unexpected peace that can come with saying goodbye. It is a reminder that a life well lived leaves an impact far beyond the final moment.
A Note from James:I talked to Nelson Dellis, who's a six-time USA Memory Champion and has broken multiple Guinness World Records. His book, Everyday Genius, makes a pretty bold claim—that with some practice and the right techniques, you can dramatically improve how your brain works.We didn't just talk about memory. We got into everything: mental math, focus, cold reading, even some techniques that feel almost like magic. And I've done a lot of episodes on memory over the years—but Nelson showed me things I hadn't seen before.What stood out to me is this idea that “genius” isn't some fixed trait. It's a collection of skills you can build. Some of them are surprisingly simple once you understand how your brain actually works.I'm definitely going to spend more time practicing some of these techniques. There's a lot here that's immediately useful—and a lot that could take years to master.Episode Description:James sits down with world memory champion Nelson Dellis to break down what memory really is—and how far it can be pushed.Nelson explains how his grandmother's battle with Alzheimer's led him into the world of memory training, eventually becoming one of the best in the world. From memorizing thousands of digits to competing in global competitions, he shows that memory is not a fixed trait—it's a skill.The conversation goes beyond memory into focus, reading, learning, and even social intelligence. Nelson shares practical techniques for improving recall, reading faster without losing comprehension, and using visualization to retain more information.They also explore the edge cases—cold reading, intuition, and even experiments with “remote viewing”—where perception and cognition blur into something that feels almost supernatural.At its core, this episode is about expanding what you believe your brain is capable of.What You'll Learn:Why memory is a trainable skill—not something you're born withHow visualization and emotional context dramatically improve recallThe difference between “speed reading” and “focus reading”Simple techniques to retain more from books and conversationsHow cold reading works (and why it feels like magic)Why reviewing information—not cramming—is key to long-term memoryThe mental habits that create the appearance of “genius”How attention and focus are becoming rare—and valuable—skillsTimestamped Chapters:00:02:00 – Nelson's origin story: Alzheimer's and the motivation to master memory 00:02:16 – Why reading is like living thousands of lives 00:03:13 – Introducing Everyday Genius and the promise of trainable intelligence 00:04:33 – Memory palace techniques and applying them to real-world skills 00:05:13 – Can memory training help prevent Alzheimer's? 00:06:13 – Daily memory training routines and measurable progress 00:08:16 – From beginner to USA Memory Champion 00:10:00 – Memorizing 10,000 digits of pi: how it actually works 00:11:31 – Turning numbers into stories: the core of memory systems 00:14:28 – Why emotion and visualization drive memory 00:16:00 – Memory competition benchmarks and world-class performance 00:18:00 – What “genius” actually means—and how to simulate it 00:20:00 – The four pillars: memory, reading, focus, and learning 00:23:33 – Speed reading vs. focus reading (and why most people get it wrong) 00:25:12 – The finger-tracking technique to instantly read faster 00:27:16 – Why you don't need to read every word 00:30:17 – Why cramming fails (and how memory actually forms) 00:31:17 – Visualization while reading: turning text into a movie 00:34:00 – Active recall, note-taking, and long-term retention systems 00:37:16 – Cold reading and social intelligence 00:41:00 – Body language cues: attention, interest, and perception 00:43:00 – How mentalists create the illusion of mind reading 00:46:00 – Psychological “forcing” and influencing choices 00:51:00 – Remote viewing experiments and cognitive edge cases Additional ResourcesEveryday Genius: Hacks to Boost Your Memory, Focus, Problem Solving and Much MoreSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Jean-Michel Ricard, cofondateur de l'association Siel Bleu et pionnier de l'activité physique adaptée en France. Je le reçois dans le cadre du Podcasthon car tous vos podcasteurs préférés cette semaine vont mettre en lumière l'association de leur choix et j'ai donc fait le choix de mettre le mouvement en avant. Jean Michel a une douceur totalement incroyable.Il y a presque 30 ans, lui et son ami Jean-Daniel se sont serré la main sur un pari un peu fou : utiliser le mouvement comme outil pour redonner de la vie, du sourire et de la dignité à des personnes que la société avait tendance à oublier. Aujourd'hui, Siel Bleu, c'est 900 salariés, 10 000 lieux d'intervention et 250 000 personnes accompagnées chaque semaine en France — des personnes âgées dépendantes, des enfants autistes, des gens en rémission de cancer, des personnes dialysées ou en soins palliatifs. Et tout ça sans jamais rentrer dans les cases.Dans cet épisode, nous parlons du mouvement comme médicament sans effets secondaires, de ce que ça veut vraiment dire de prendre soin des gens en fragilité, et de la différence entre le confort à court terme et la santé à long terme. J'ai questionné Jean-Michel sur la naissance de Siel Bleu, sur ce que la science dit vraiment de l'activité physique face à Alzheimer, Parkinson ou le cancer du sein, sur les "séjours hors du temps" pour jeunes adultes en fin de vie, et sur ce que 30 ans d'engagement associatif lui ont appris sur ses angles morts. C'est une conversation pleine de douceur, de conviction et de sagesse concrète.CITATIONS MARQUANTES"L'activité physique, ça devrait être le médicament du XXIe siècle. Ça n'a aucun effet secondaire, ça coûte pas cher, et ça change la vie des gens.""Après avoir donné des années à la vie, donnons de la vie aux années." — le premier slogan de Ciel Bleu, qui résume tout."Si on ferme la porte, on passera par la fenêtre. Et il faut qu'ils en soient sûrs.""La vie est la plus belle des garces. Tout ce qu'on croit qui est gagné, c'est jamais gagné.""Celui qui s'est penché sur une fleur n'aura pas vécu en vain." — citation de Christian Bobin, convoquée pour parler de prendre le temps d'écouter son corps.IDÉES CENTRALES 1. Le mouvement est un outil, pas une finalité Ciel Bleu ne fait pas du sport pour faire du sport. L'activité physique adaptée est un vecteur de reconquête : physique (réduction des chutes, de la sarcopénie, des escarres), cognitif (ralentissement d'Alzheimer, de Parkinson), et social (recréer du lien, sortir de l'isolement). Ce cadrage est fondamental : il déplace le mouvement de la performance vers la vie. Timestamp : 06:33 – 07:542. La prévention coûte moins cher que le curatif — mais personne n'investit dedans La France est dans un modèle de santé essentiellement curatif. Jean-Michel plaide pour une partie du budget de la Sécu investie en prévention pluriannuelle. Les chiffres sont là : plus de 10 000 personnes âgées meurent chaque année en France suite à des chutes. Le programme Ossebo, publié dans le British Medical Journal, l'a démontré : l'activité physique réduit significativement ces hospitalisations. Timestamp : 16:52 – 17:22 et 13:38 – 14:523. Les "séjours hors du temps" : redonner le choix à ceux qui n'en ont plus Pour des jeunes ados et jeunes adultes dont le pronostic vital est engagé, Ciel Bleu a imaginé des séjours d'une semaine où tout est construit avec eux — famille ou pas, amis ou pas — pour démontrer que la joie de vivre peut être présente jusqu'au bout. Un frère a écrit un article bouleversant sur son frère décédé, décrivant ce séjour comme le meilleur moment de sa vie. Timestamp : 22:11 – 24:284. L'écart salarial 1 à 3 comme ciment organisationnel Il y a 30 ans, avant que ça devienne tendance, Ciel Bleu a inscrit dans ses principes fondateurs un écart de salaire de 1 à 3 entre le moins et le mieux payé. À 900 salariés, ce principe tient encore. Ce n'est pas un gadget RSE : c'est un choix structurant qui dit quelque chose de fort sur ce qu'on considère juste dans une organisation. Timestamp : 29:41 – 30:225. Donner envie d'avoir envie — et pas moraliser La pédagogie de Ciel Bleu repose sur une conviction : on ne force pas, on ne culpabilise pas, on fait naître l'envie. Jean-Michel convoque Jacques Brel ("donner envie d'avoir envie") pour décrire le savoir-faire de ses collègues. Travailler sur les capacités restantes, jamais sur les incapacités. Ne jamais mettre les gens en échec. Timestamp : 27:25 – 28:48 et 43:26 – 44:326. L'être humain n'est pas fait pour s'asseoir Jean-Michel et Gregory s'accordent sur une vérité physiologique inconfortable : l'humain est un marcheur-cueilleur. La sédentarité est une anomalie évolutive. Le confort à court terme (sièges gaming, vélos électriques, télécommandes) masque une dégradation lente mais certaine. Et la discipline pour y résister n'est pas naturelle — elle s'apprend. Timestamp : 56:08 – 57:53 QUESTIONS POSÉES DANS L'INTERVIEWComment est née l'association Ciel Bleu, et qu'est-ce qui vous a poussés, toi et Jean-Daniel, à créer ça à la sortie de la fac ?Il y a 30 ans, le mouvement vous semblait déjà fondamental pour les personnes âgées — pourquoi ?Qu'est-ce que le mouvement permet vraiment, à tous les niveaux — physique, cognitif, social ?Où en est Ciel Bleu aujourd'hui, en chiffres et en principes ?Comment ça fonctionne concrètement pour quelqu'un en rémission d'un cancer du sein qui veut vous contacter ?C'est quoi les "séjours hors du temps" et comment cette idée est née ?Vous faites des groupes de niveaux, vous mélangez les publics — comment vous gérez la diversité des profils ?Qu'est-ce que tu conseilles à quelqu'un de bien portant pour prendre soin de son corps avant d'avoir besoin de vous ?Comment tu regardes l'explosion des mobilités électriques, les vélos assistés, les trottinettes — bonne ou mauvaise nouvelle pour le mouvement ?Qu'est-ce que ces 30 ans d'expérience t'ont appris sur tes angles morts ?RÉFÉRENCES CITÉES DANS L'ÉPISODEPersonnesChristian Bobin (poète) — cité pour la phrase "Celui qui s'est penché sur une fleur n'aura pas vécu en vain", à propos de prendre le temps d'écouter son corps. ~37:29Gilles Deleuze — cité pour sa phrase d'introduction à Vincennes : "Soyons joyeux pour résister." ~58:04Jacques Brel (inféré, "grand poète belge-français") — "Donner envie d'avoir envie." ~27:25Elon Musk — mentionné en négatif pour sa posture sur la consommation des data centers et l'idée de coloniser Mars. ~53:19Olivier Hamon — mentionné en lien avec le concept de robustesse. ~54:04Daniel Kahneman — mentionné par Gregory (système 1/système 2) pour parler de la fainéantise physiologique de l'humain. ~56:08Alexandre Dana — auteur du livre "La chaise tue", cité en référence à un épisode précédent de VLAN sur le mouvement. ~02:54 et 57:27Jean-Daniel Muller — cofondateur de Ciel Bleu, évoqué tout au long de l'épisode.Institutions & programmesInserm — partenaire scientifique du programme Ossebo sur la prévention des chutes. ~13:38BMJ (British Medical Journal) — journal ayant publié les résultats du programme Ossebo. ~13:38Fédération des banques alimentaires — partenaire associatif de Ciel Bleu. ~17:31STAPS (Sciences et Techniques des Activités Physiques et Sportives) — formation initiale de Jean-Michel et Jean-Daniel. ~03:48Programmes internes Ciel BleuOssebo — programme de recherche avec l'Inserm sur la prévention des chutes, 7 ans, l'un des plus grands au monde. ~13:38Maisons de Vie — séjours de récupération pour personnes en rémission de cancer. ~19:41Séjours hors du temps — séjours pour jeunes ados/adultes en fin de vie. ~22:49Campagne "Un pas de côté" — campagne grand public lancée en parallèle des JO, avec Paulette (92 ans, médaillée du 30 mètres couloir), Marianne (dialyse) et Audrey (troubles autistiques). ~46:53TIMESTAMPS CLÉS 00:00 — Introduction : le mouvement comme outil de vie Grégory pose le cadre : dans une société de confort, on bouge de moins en moins sans réaliser le mal qu'on se fait. Jean-Michel Ricard, fondateur de Ciel Bleu, arrive pour changer ce regard.03:48 — La naissance de Ciel Bleu Jean-Michel raconte comment lui et Jean-Daniel, étudiants en STAPS, ont décidé de tout planter pour créer une asso dédiée aux personnes âgées. Un article de presse, un coup de téléphone, une poignée de main — et 30 ans d'aventure humaine ont commencé.06:33 — Pourquoi le mouvement change tout Trois niveaux d'impact : physique (réduction des chutes et fractures), cognitif (confiance en soi, prise de risque), et social (recréer du lien quand l'isolement s'installe). Le mouvement comme médicament sans ordonnance.08:40 — 900 salariés, 250 000 personnes, 10 000 lieux L'état des lieux de Ciel Bleu aujourd'hui : une organisation qui a grandi sans jamais renier ses principes fondateurs, avec un modèle économique solidaire et une mission claire : que rester en bonne santé reste un droit, pas un luxe.13:38 — Le programme Ossebo et la science derrière 7 ans de recherche avec l'Inserm, publié dans le British Medical Journal : l'activité physique adaptée réduit significativement les chutes avec hospitalisation chez les personnes âgées. Ce n'est pas du bien-être — c'est de la médecine préventive prouvée.19:41 — Les Maisons de Vie pour les personnes en rémission de cancer Des séjours d'une semaine pour poser "la valise de la vie" : sport, alimentation, ateliers d'écriture, astrophysique. Pour se rappeler que la vie est belle jusqu'au bout, quoi qu'il arrive.22:11 — Les séjours hors du temps : l'incroyable histoire Pour des jeunes ados dont le pronostic vital est engagé, Ciel Bleu imagine des semaines où tout appartient à la personne. L'histoire d'un frère qui écrit un article bouleversant sur son frère décédé, racontant ce séjour comme le meilleur moment de sa vie.29:41 — Construire une asso hors des cases : 30 ans de résistance L'écart salarial de 1 à 3, les portes fermées, les financeurs qui ne comprennent pas. Jean-Michel parle franchement des difficultés de ne jamais rentrer dans les cases, et de ce qu'il ferait différemment.40:24 — Des exemples concrets : AVC, Parkinson, Alzheimer Un homme donné pour invalide à vie après un AVC au Limousin remarche et refait son jardin. Des programmes scientifiques qui montrent que l'activité physique ralentit la progression d'Alzheimer. Des histoires vraies, pas des promesses.46:53 — La campagne "Un pas de côté" : Paulette, Marianne, Audrey Lancée en parallèle des JO, cette campagne met en scène trois femmes — 92 ans en déambulateur, dialyse sur vélo, troubles autistiques — pour dire que les grandes victoires sont faites de petits pas. Bouleversant et juste.54:20 — Ce qui donne envie du futur Les jeunes, la robustesse, la joie rebelle de Grégory, Deleuze à Vincennes — une fin d'épisode qui remonte le moral et donne une vraie raison d'aller de l'avant.59:54 — Les angles morts de 30 ans d'engagement La question finale, inattendue : Jean-Michel parle de s'entourer de mieux que soi, d'une colère transformée en actes, et de cette vérité dure — rien n'est jamais acquis. La liberté, l'amour, la République. Il faut en prendre soin. Suggestion d'autres épisodes à écouter : #366 Pouquoi votre bureau vous rend malade? Avec Alexandre Dana (https://audmns.com/vHxgVHq) #322 Démystifier le bien-être avec Major Mouvement (https://audmns.com/IfubNER) #257 Se réapproprier ses émotions à travers le corps avec Bolewa Sabourin (https://audmns.com/hNQWsty)Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this special episode, Peter takes a deep dive into obicetrapib, an investigational drug that has captured his attention and renewed interest in an entire class of therapies known as CETP inhibitors. He explains what obicetrapib is and how it works, revisits the history of CETP inhibitors and why earlier versions of these drugs failed—sometimes dramatically—and breaks down the key clinical trials designed to evaluate their impact on cardiovascular risk. Peter examines how obicetrapib influences major lipid biomarkers, including LDL cholesterol and lipoprotein(a) [Lp(a)], and discusses emerging evidence from a study that explored the drug's effects on Alzheimer's-related blood biomarkers. He also highlights intriguing findings in individuals carrying the APOE4 allele and reflects on what these early results may mean for both cardiovascular disease prevention and potential implications for Alzheimer's risk, as well as how he is thinking about this therapy in the context of caring for his own patients. We discuss: Introducing obicetrapib: CETP inhibitor history, lipid biology, and early Alzheimer's biomarker signals in APOE4 carriers [2:15]; CETP biology explained: lipoproteins, reverse cholesterol transport, and how CETP inhibition alters HDL and LDL particles [5:15]; The early CETP inhibitor story: why raising HDL cholesterol alone failed to deliver cardiovascular protection [13:45]; The rise and fall of early CETP inhibitors: torcetrapib, dalcetrapib, evacetrapib, and anacetrapib [18:30]; Why obicetrapib may succeed where earlier CETP inhibitors failed [23:30]; The BROADWAY trial: obicetrapib's effects on LDL, ApoB, Lp(a), and residual cardiovascular risk [26:00]; Brain lipid metabolism and APOE4: how CETP inhibition may influence cholesterol transport in Alzheimer's disease [30:45]; Findings from the substudy of the BROADWAY trial which looked at changes in biomarkers of Alzheimer's disease [40:00]; Interpreting the BROADWAY Alzheimer's biomarker results: limitations, cautious optimism, and the need for a dedicated prevention trial [46:45]; Why Peter is optimistic about obicetrapib: cardiovascular benefits, Lp(a) reduction, and the path toward approval [50:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
Neurologist Dr. Majid Fotuhi, author of The Invincible Brain, joins me to break down the most powerful lifestyle habits for protecting your brain, staying sharp as you age, and reducing your risk of dementia.15 Daily Steps to Lose Weight and Prevent Disease PDF: https://bit.ly/46XTn8f - Get my FREE eBook now!Subscribe to The Genius Life on YouTube! - http://youtube.com/maxlugavereWatch my new documentary Little Empty Boxes - https://www.maxlugavere.com/filmThis episode is proudly sponsored by:Wildgrain slow-fermented sourdough and fresh pastries go from freezer to bakery-level perfection in under 25 minutes. Yum! Get $30 off your first box and free croissants in every box at Wildgrain.com/MAX or use code MAX at checkout.Fatty15 provides C15:0, a naturally occurring fatty acid found in full-fat dairy that may support cellular health and longevity—get 15% off at http://fatty15.com/MAX with code MAX!
Join us as we review and appraise recent practice-changing articles. In this episode, we cover the latest in GLP-1s and GIP agonists for CVD, Type 2 Diabetes, and Obesity, valacyclovir to treat Alzheimer's, weight regain patterns after medication-induced weight loss, and a deep dive into the data behind deprescribing – and behavioral science to increase deprescribing behavior. Fill your brain hole with a delicious stack of hotcakes! Featuring Paul Williams (@PaulNWilliamz), Alex Chaitoff (@alexchaitoff), Nora Taranto (@norataranto), & Matt Watto (@doctorwatto).Claim CME for this episode at curbsiders.vcuhealth.org!Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CMECredits Written and Hosted by: Nora Taranto MD, MSCE; Alexander Chaitoff MD, MPH; Paul Williams, MD, FACP,, & Matthew Watto MD, FACP Cover Art: Nora Taranto MD, MSCE Reviewer: Sai S Achi MD, MBA, FACP Technical Production: Pod Paste Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Show Segments Intro, disclaimer GLP-1 + GIPs vs GLP-1s for patients with T2DM and Obesity – SURPASS-CVOT Weight Regain after Weight loss VALAD – Valacyclovir in patients with early Alzheimer's Nudges to increase Deprescribing Outro Sponsor: MedStudy Qbank Study less. Remember more. Pass confidently.Medstudy.com/CurbsidersCURB15 for 15% offSponsor: FIGSWe've teamed up with FIGS, and now Curbsiders listeners can get 15% off at Wearfigs.com with code FIGSRX. Sponsor: QuinceRight now, go to Quince.com/curb for free shipping and 365-day returns. Sponsor: A Dangerous DiagnosisTo get 20% off use DIAGNOSIS20 at www.penguinrandomhouse.com/books/808848/a-dangerous-diagnosis-by-shantanu-rai/paperback/
This episode is brought to you by AX3 Life, Strong Coffee Company and WHOOP. Today we sit down with neurologist and brain health expert Majid Fotuhi, MD, PhD, author of The Invincible Brain, to challenge conventional thinking about Alzheimer's disease and cognitive decline. Dr. Fotuhi explains why Alzheimer's may not be a single disease but rather the result of multiple processes—including inflammation, poor sleep, metabolic dysfunction, and lifestyle factors—that accumulate over time. The conversation explores the science behind brain shrinkage, the role of sleep in clearing toxins from the brain, why exercise may be one of the most powerful tools for cognitive health, and the five pillars of brain fitness: exercise, sleep, nutrition, stress reduction, and brain training. He also shares clinical research showing that targeted lifestyle changes can significantly improve cognitive performance and even increase hippocampal volume in patients with mild cognitive impairment, offering a hopeful perspective on protecting and strengthening the brain as we age. ----- 00:00 – Why Alzheimer's may not be a single disease 02:34 – The "soup of problems" explanation for Alzheimer's 03:21 – Why many dementia diagnoses miss treatable causes 04:01 – Treating lifestyle factors that affect brain health 06:30 – Understanding mild cognitive impairment (MCI) 10:15 – Brain shrinkage and inflammation explained 15:12 – Why lifestyle affects brain aging 20:40 – The role of exercise in brain health 28:22 – How exercise helps grow new neurons 29:11 – Exercise and the brain's waste-clearing system 30:03 – Why sleep is critical for brain detox 31:20 – The five pillars of brain health 33:45 – Why there is no "miracle cure" for brain health 38:10 – How small daily habits compound over time 45:44 – Research showing the brain can grow again 48:11 – MCI vs Alzheimer's diagnosis explained 49:28 – Risk factors that can accelerate dementia 50:13 – Clinical results improving cognitive performance 52:00 – Ever Forward ----- Episode resources: Save 20% on the super-antioxidant astaxanthin from AX3 Life with code EVERFORWARD Save 15% on organic coffee and lattes from Strong Coffee Company with code CHASE Get a FREE WHOOP 5.0 sleep and activity tracker Watch and subscribe on YouTube Get Dr. Fotuhi's book The Invincible Brain
The Alzheimer’s Foundation of America is holding a free one-day conference in Portland on Wednesday designed for patients, families and caregivers. One of the keynote speakers is the co-director of the state’s only Alzheimer’s Disease Research Center, Oregon Health and Science University’s Kevin Duff. He says early detection recommendations have changed over recent years and with the emergence of new drugs, many early stage patients can experience dramatically improved outcomes — so catching the disease early is critically important. Duff joins us in studio to discuss the details.
What happens when an Air Force officer, aerospace engineer, trauma chaplain, and Alzheimer's caregiver sits down to write thrillers? In this deeply moving episode of The Self Esteem and Confidence Mindset, we sit down with Larry Patzer—author of thrillers built on real people's lived situations, nationally certified Spiritual Director, former trauma chaplain, and nine-year Alzheimer's caregiver—to explore how facing life's hardest moments shapes storytelling, builds resilience, and teaches us how to live better.Larry shares wisdom from his unique journey: nineteen years designing high-stakes aerospace intelligence systems where failure wasn't an option, sitting with families in trauma as an on-call chaplain, caring for a loved one through Alzheimer's, and translating all of it into fiction that honors human stakes and the weight of choices. His perspective on consequences, suffering, resilience, and meaning will resonate whether you're a writer, caregiver, person of faith, or anyone navigating life's hardest chapters.You can find more from Larry here:Website: https://coffeecuppublishing.com/Amazon Book link: https://www.amazon.com/PAST-ALWAYS-COMES-BACK-help/dp/1970576243/
Send a textEddie Rodriguez is the founder and host of BrainHeal(th), an educational YouTube channel dedicated to sharing what he and his family have learned and are learning in caregiving for his father, diagnosed with early-onset Alzheimer's disease.Eddie is an advocate for metabolic neurology, metabolic psychiatry, and cognitive health strategies, like the Bredesen Protocol, for the prevention and treatment of neurological and psychiatric disorders. With extensive experience in commercial financing, corporate- and sales-process consulting, and leadership development, he combines his professional expertise with a passion for transforming how mental and neurological conditions are framed and treated going forward.He is also the Board President of Metabolic Collective, a new 501(c)(3) whose mission is to accelerate the real-world adoption of metabolic therapies (especially ketogenic protocols) for serious mental illness and neurological disorders by building a global, peer-led grassroots movement.Find Eddie at-YT- @BrainHeal_th_https://metaboliccollective.org/Find Boundless Body at- myboundlessbody.com Book a session with us here!
We hang with Kevn Kinney of Drivin N Cryin and Johnny Hickman of Cracker in Athens, GA and trace how songs and scenes shape a life, from new releases to punk rock beginnings. Kevn opens up about writing “Mirror Mirror,” a power pop song about Alzheimer's, with a chorus built around one hard line: “I know you're in there somewhere.” We talk about what memory loss looks like up close, and the quiet fear hiding in the last verse when the writer starts seeing himself in the mirror.Johnny Hickman joins with the kind of honesty and humor that makes decades of touring feel lived-in, not polished. We get into Cracker's annual Camp-In and what it takes to rehearse an album like The Golden Age for a 30th anniversary performance, down to relearning parts and chasing the original guitar tones. Athens comes up as more than a backdrop: it's a small town with a big music history, a place where friendships with R.E.M. and long nights of shows still echo, and a place Kevn describes as genuinely healing.From there, the conversation opens into punk rock origins, why hooks outlast hype, and how careers can flip overnight. We swap stories about opening bands and the line every musician has to walk with fans. If you love rock history, songwriting craft, and the real human side of touring musicians, this one's for you. Learn Something New orRemember Something OldPlease like and follow the Music in My Shoes Facebook and Instagram pagesReach out to us at musicinmyshoes@gmail.comSend us a one-way message. We can't answer you back directly, but it could be part of a future Music In My Shoes Mailbag!!!
Full Show Notes: bengreenfieldlife.com/498 In this solosode I kick off by talking about whether isometric training is worth your time, covering both my own fitness habits and the newest research, particularly for runners and joint health. I also unpack a buzzworthy study on how just 10 minutes of vigorous exercise daily can be a powerful longevity booster compared to longer, lighter workouts. I share why I no longer personally use metformin, and instead, offer my favorite natural alternatives for better blood sugar control—like berberine, fiber, cinnamon, and simple routines like salads and walks. Plus, I get into brain health, explaining the roles of ketones, methylene blue, and near-infrared light for cognitive performance and protecting against issues like Alzheimer’s. At the end, I answer listener questions on optimizing DHT levels, natural insulin-sensitizers, and keeping your hair healthy even if you’re on testosterone. If you’re interested in practical strategies and learning what’s currently working in my own routine, you’ll enjoy this episode. Episode Sponsors: Hiya: Give your kids the full-body nourishment they need to grow into healthy adults. I’ve secured a special deal with Hiya on their best-selling children's vitamin—get 50% off your first order today! To claim this deal, you must go to hiyahealth.com/BEN (it is not available on their regular website). BASED Bodyworks: BASED Bodyworks is a clean, plant-based men's grooming brand offering simple, high-performance essentials from shampoo and skincare to styling, formulated without harsh sulfates or hormone-disrupting chemicals, so you can look and feel your best without compromising your health. Visit basedbodyworks.com and use code BOUNDLESSLIFE for 20% off. Manukora: You haven’t tasted or seen honey like this before - so indulge and try some honey with superpowers from Manukora. If you head to manukora.com/ben or use code BEN, you’ll automatically get $25 off your Starter Kit. Apollo: Apollo is a safe and non-invasive wearable that actively improves your sleep. Head over to apolloneuro.com/bengreenfield and use code BENGREENFIELD for $90 off.See omnystudio.com/listener for privacy information.
Instead of a long goodbye, imagine a nine-year journey filled with newfound creativity, laughter, and deep connection. In this episode of Real Things Living, Brigitte Cutshall talks with Marilyn Raichle, author of "Don't Walk Away: A Care Partner's Journey." Marilyn shares how her mother's late-life discovery of painting transformed their relationship from one of "caregiver and patient" to true "care partners".KEY DISCUSSION POINTS(1) Art as an Anchor: Marilyn discovered that while Alzheimer's is scary, art is not; it allows the person living with dementia to be present and their true self to emerge.(2) The Power of Listening: Marilyn shifted from "being raised to win" to learning the art of listening, discovering that her mother always had something left to teach.(3) Living vs. Suffering: A central theme of the conversation is the importance of saying a person is "living with" dementia rather than "suffering from" it, acknowledging their ongoing value and humanity.(4) Innovation in Care: As Executive Director of the Maudes Awards, Marilyn highlights how they provide $100,000 in annual gifts to individuals and organizations finding innovative ways to bring joy to those with memory loss.Insights for Care Partners:(1) The Five-Minute Rule: If you are struggling to connect, find one simple thing you both enjoy—a walk, a song, or a sunset—and do it for just five minutes.(2) Emotional Memory: Even if a loved one cannot remember the specifics of a visit, they retain the positive emotion and "joy" that the interaction provided.ResourcesWebsite: https://dontwalkaway.net The Maude's Awards: https://maudesawards.org
L'IA va-t-elle remplacer votre médecin ? 230 millions de personnes utilisent déjà ChatGPT pour leur santé chaque semaine. Dans cet épisode, on décrypte la grande offensive santé d'OpenAI, Amazon et des géants de la tech — et ce que ça change vraiment pour les patients, les médecins et le système de santé.Au programme : ChatGPT Health, les World Models d'AMI Labs, Insilico Medicine, les capteurs d'ondes cérébrales, les lunettes connectées, la neurostimulation anti-Alzheimer, et la question qui divise — peut-on faire de ChatGPT son psy ?===========================
In this powerful and science-forward episode of the Tick Boot Camp Podcast, host Matt Sabatello sits down with Amy Proal, PhD, a leading microbiologist whose work is reshaping how the medical community understands chronic Lyme disease, post-treatment Lyme disease (PTLD), ME/CFS, and Long COVID. Dr. Proal brings a rare combination of deep scientific expertise, lived experience with chronic illness, and real-world clinical integration, offering listeners clarity on why so many patients remain sick long after standard treatment ends — and what science is finally doing about it.
Program notes:0:44 Adolescents and sleep duration1:44 Very short sleep duration2:44 Increased among all subgroups3:45 Structural factors more important4:45 Moving school start later5:02 GLP1 agonists and various patient characteristics6:02 Greater weight loss in women7:06 A blood test to predict onset of symptomatic Alzheimer's8:06 Median error of 3-4 years9:06 Window of 11.4 years for an 80 year old10:05 Screening for colorectal cancer 11:05 Colonoscopy and FIT diagnosed early12:33 End
A fascinating new study reveals a previously underappreciated pathway for tau clearance in the brain. Researchers show that tanycytes—specialized hypothalamic glial cells—actively transport tau from cerebrospinal fluid into the bloodstream. In Alzheimer disease, these cells become fragmented and dysfunctional, impairing tau clearance and potentially accelerating neurodegeneration. This work opens an intriguing avenue: could restoring tanycyte function enhance tau removal and slow Alzheimer progression? A small cellular gatekeeper may hold an important clue in the battle against dementia. Source: Sauvé F et al. Tanycytic degeneration impairs tau clearance and contributes to Alzheimer's disease pathology. Cell Press Blue, 2026.
What health habits actually protect your brain and long-term health? In this episode, Professor Tim Spector shares the seven health ideas he has changed his mind about after reviewing new research. From oral health and inflammation to vitamin D, sleep, and exercise, Tim explains the daily habits he now prioritises and helps us understand what we should do differently if the science changes. Tim revisits 7 common health beliefs and explains how new evidence has shifted his thinking. He explores the link between oral health, inflammation and brain ageing, and discusses vitamin D, sunlight and omega-3s. The conversation also looks at sleep timing, exercise and how everyday habits interact with our biology. Tim also shares the small changes he now makes in his own routine and provides practical ideas for incorporating them into your daily life. We all know that science evolves as new evidence emerges, so if the research changes, should our daily health habits change too?
It's an era of breakthroughs in Alzheimer's research, yet for many clinicians, it's also a time of profound uncertainty. We are currently navigating competing definitions of the disease, multiple new biomarkers coming on market seemingly every week, and the clinical rollout of new amyloid antibodies. How do we translate this rapid-fire science into daily practice? On this week's GeriPal podcast, we sit down with dementia experts Halima Amjad, Barak Gaster, and Heather Whitson. We dive deep into: The evolving definitions of Alzheimer's disease. Does someone have Alzheimer's disease if you have only an abnormal biomarker as defined by the Alzheimer's Association, or is amyloid pathology necessary but not sufficient to define Alzheimer's as per the International Working Group (IWG) recommendations? Where do blood-based biomarkers for Alzheimer's fit into the diagnostic workup, and should they be used at all in primary care? FYI - here is my take on that question in a recent JAMA IM article titled "The Limited Role of Alzheimer's Disease Blood-Based Biomarkers in Primary Care." What's the role of amyloid antibodies in the care of individuals with Alzheimer's disease, including who to use them on? We covered a lot and discussed some of these resources that you can do a deeper dive on: Blood-based biomarker resources JAMA article on Blood-Based Biomarkers for Alzheimer's Disease: Preventing Unintended Consequences Alzheimer's Dementia article on Blood-based biomarkers for detecting Alzheimer's disease pathology in cognitively impaired individuals within specialized care settings: A systematic review and meta-analysis JAMA IM article on The Limited Role of Alzheimer Disease Blood-Based Biomarkers in Primary Care Appropriate use recommendations for amyloid antibodies Donanemab: Appropriate use recommendations Lecanemab: Appropriate Use Recommendations Primary Care Resources Cognition in Primary Care program A JAGS article on "Large Health System Quality Improvement Intervention Providing Training and Tools to Improve Detection of Cognitive Impairment in Primary Care" Other resources AGS's new online curriculum for Alzheimer's Disease By Eric Widera
Ahead of the 30th anniversary of the Dunblane massacre on Friday, presenter Anita Rani speaks to three women whose lives changed for ever that day; Melanie Reid, a journalist who was one of the first at the scene in Dunblane that morning, Rosemary Hunter, one of three women leaders of The Snowdrop Campaign that changed UK gun laws and Anna Hall, who grew up in Dunblane and is the director of a Channel 4 documentary about the shootings, The Dunblane Tapes.How would you feel if everyone in your household forgot your birthday? After a woman's social media post saying her family had forgotten hers went viral, Anita talks to the author Poorna Bell and the journalist Nell Frizzell about whether forgetting a spouse's birthday is simply a careless moment or the sign of something deeper.Catfishing is the act of creating a fake online persona to deceive others for romantic, financial, or malicious reasons. This happened to 19-year old Sasha-Jay Davies, from Aberdare in Wales who for almost four years has been accused of leading men on, arranging to meet them and not showing up, and been harassed by complete strangers, all because someone else has been using her photos without permission on social media. BBC Wales reporter Eleri Griffiths has been covering the story and joins us along with Reagan Brien, a solicitor at Cohen Davis who has worked on similar cases.New research carried out by the University of California in the US has revealed that a blood test can detect dementia in women, years before they have symptoms. Dr Sheona Scales, director of research at Alzheimer's Research UK, explains the research findings and what it could potentially mean for women's dementia diagnosis in the future.Presenter: Anita Rani Producer: Rebecca Myatt
If you are dealing with fatigue that won't lift, brain fog that clouds your thinking, or immune symptoms that flare unpredictably, this episode will help you understand why your gut may be influencing all of them.In this episode of Renegade Remission, we explore how the microbiome regulates immune balance, neurological function, and systemic signaling far beyond digestion.You'll hear a real clinical example from ulcerative colitis research showing that when the microbial ecosystem shifts, immune behavior shifts alongside it. From there, we break down the mechanisms linking gut imbalance to fatigue, cognitive changes, barrier dysfunction, and immune dysregulation. Finally, we look at immune training in the gut, intestinal permeability, the gut–brain axis, short-chain fatty acids, and microbial roles in detoxification..In this episode, you'll understand:Why gut imbalance can influence energy, cognition, and immune stabilityHow microbial signaling shapes systems far beyond digestionThe connection between barrier integrity and whole-body symptomsWhy neurological and immune symptoms often overlapThe most realistic ways to begin supporting gut balance without restrictive dietsInstead of treating symptoms as separate problems, you'll see how they may share a common regulatory hub.Listen now to understand how your gut may be influencing fatigue, cognitive clarity, and immune function and choose one gentle shift you can begin this week.DisclaimerThis podcast is for educational purposes only and does not offer medical advice. Consult your licensed healthcare provider before making any changes to your treatment or health regimen. Reliance on any information provided is solely at your own risk.This podcast explores stories and science around ALS, dementia, MS, cancer, mind body recovery, healing, functional medicine, heart disease, regression, remission, integrative medicine, autoimmune conditions, chronic illness, terminal disease, terminal illness, holistic health, quality of life, alternative medicine, natural healing, lifestyle medicine, and remission from cancer, offering hope and insights for those seeking resilience and renewal.
Brain Talk | Being Patient for Alzheimer's & dementia patients & caregivers
After Deborah Kan's mother, Alvera Kan, died in December of last year, the family donated her brain to UCSF to better understand what type of dementia she had. The answer came back with not just one diagnosis, but three different types of dementia: Alzheimer's disease, vascular dementia, and LATE. Kan and her sister, Susan Whitaker, are joined by Dr. Bruce Miller, director of the UCSF Edward and Pearl Fein Memory and Aging Center, and Dr. David Soleimani-Meigooni, a neurologist at UCSF's Memory and Aging Center and assistant professor focused on precision diagnosis in Alzheimer's and related neurodegenerative diseases. Miller's work has helped shape how clinicians identify and distinguish different forms of dementia, including frontotemporal dementia, while Soleimani-Meigooni's clinical and research work includes using imaging and biomarkers to better understand amyloid, tau and other drivers of cognitive decline.In this conversation with Kan and Whitaker, Miller and Soleimani-Meigooni discuss how dementia diagnosis can remain uncertain during life and how an autopsy can reveal multiple diseases. They underscores how common mixed dementias are, why symptoms such as getting lost or struggling with numbers can point to specific brain changes, and why better diagnostic tools are needed. They also highlight the lasting scientific value of brain donation, showing how one family's decision can contribute to more precise diagnoses, better biomarkers, and, ultimately, more individualized treatment approaches for future patients.---If you loved listening to this Live Talk, visit our website to find more of our Alzheimer's coverage and subscribe to our newsletter: https://www.beingpatient.com/Follow Being Patient: Twitter: https://twitter.com/Being_Patient_Instagram: https://www.instagram.com/beingpatientvoices/Facebook: https://www.facebook.com/beingpatientalzheimersLinkedIn: https://www.linkedin.com/company/being-patientBeing Patient is an editorially independent journalism outlet for news and reporting about brain health, cognitive science, and neurodegenerative diseases. In our Live Talk series on Facebook, former Wall Street Journal Editor and founder of Being Patient, Deborah Kan, interviews brain health experts and people living with dementia. Check out our latest Live Talks: https://beingpatient.com/live-talks/
PeerView Family Medicine & General Practice CME/CNE/CPE Video Podcast
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/EBAC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/VAD865. CME/EBAC/NCPD/AAPA/IPCE credit will be available until 8 March 2027.Strategies for Appropriate Assessment and Use of APOE Status in Alzheimer's Disease: Clinical Care in Europe In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
Hannah Richardson lives in St. Louis and is 25, or in her words, “currently 14 years away from my age of onset “ for Alzheimer's disease. Her family has a rare genetic form of the condition that impacts people in their late 30s and early 40s.
This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/EBAC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/VAD865. CME/EBAC/NCPD/AAPA/IPCE credit will be available until 8 March 2027.Strategies for Appropriate Assessment and Use of APOE Status in Alzheimer's Disease: Clinical Care in Europe In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.
Topics discussed on today's show: National Promposal Day, Johnny Appleseed, Music News, NBA Points, Science News, Blood Tests for Alzheimer's, Dance to this Song, History Quiz, Celeb Billionaires, Get The Fake Out, Toxic Femininity, Studio Session: Kelly Clarkson - Since U Been Gone, and Apologies.
Meet sandwich generation caregiver Brendan Kelso, who shares his journey caring for his mom with Alzheimer's while also supporting his son with ASD. Brendan discusses embracing vulnerability and how therapeutic writing—even just 15 minutes a day—helps him process the messy parts of life and the mental traffic that shows up at night when sleep feels impossible. You'll learn how creativity weaves through Brendan's caregiving life—from thrifting books with his son to run an eBay bookstore, to adapting extended plays into child-friendly experiences, to writing a debut mystery-thriller inspired by his mother's Alzheimer's journey, and even transforming her former tiny home into a brick-and-mortar bookstore. We also dive into the importance of saying no, accessing California caregiver support, and finding meaningful ways to adapt when life doesn't go as planned. Show notes with product and resource links: https://bit.ly/HHCPod223 Receive the podcast in your email here: http://bit.ly/2G4qvBv Order a copy of Elizabeth's book Just for You: a Daily Self Care Journal: http://bit.ly/HHCjournal For podcast sponsorship opportunities contact Elizabeth: https://happyhealthycaregiver.com/contact-us/ The Happy Healthy Caregiver podcast is part of the Whole Care Network. Rate and Review the podcast: https://bit.ly/HHCPODREVIEW
Estás escuchando #JUNTOSRadio: Cuidarme para cuidarte: Alzheimer y el diagnóstico temprano. ¿Cómo diferenciamos entre envejecimiento normal y señales de alerta?, ¿Cuál es la diferencia entre demencia y Alzheimer?, ¿Qué estrategias prácticas pueden facilitar el día a día en casa? El Dr. Jamie Perales, profesor asistente en el Centro de Investigación de la Enfermedad de Alzheimer de la Universidad de Kansas nos responde a estas otras preguntas. Sobre nuestro invitado: Jaime Perales Puchalt, Ph.D., MPH, es profesor asistente en el Centro de Investigación de la Enfermedad de Alzheimer de la Universidad de Kansas. Su formación es en psicología y salud pública. Además de realizar investigaciones en España, Inglaterra y Estados Unidos, Perales Puchalt ha colaborado con equipos de otros países de la Unión Europea y las Américas. El Dr. Perales Puchalt tiene un doctorado en biomedicina y salud pública y un MPH en salud pública de la Universidad Pompeu Fabra, Barcelona. También tiene una maestría en psicología de la Universidad de Valencia. Se unió a la KU ADRC en 2017 después de un puesto postdoctoral en JUNTOS: Center en el KU Medical Center. Recursos informativos en español CuidaTEXT https://www.juntosks.org/cuida-text https://www.kumc.edu/research/alzheimers-disease-research-center/care-and-support/en-espanol.html Asociación de Alzheimer apoyo a cuidadores https://www.alz.org/es-mx/ayuda-y-apoyo Facebook: @juntosKS Instagram: juntos_ks YouTube: Juntos KS Página web: www.juntosks.org Suscríbete en cualquiera de nuestras plataformas de Podcast: Podbean, Spotify, Amazon Music y Apple Podcast - Juntos Radio Centro JUNTOS 4125 Rainbow Blvd. M.S. 1076, Kansas City, KS 66160 Este programa es únicamente con fines educativos. Para recibir un diagnóstico o tratamiento, consulte a su médico. La información proporcionada por el invitado es responsabilidad de este. No tenemos los derechos de autor de la música que aparece en este video. Todos los derechos de la música pertenecen a sus respectivos creadores.
Parkinson's is not a function of aging, it is not a genetic disease and it is a human caused disease that is entirely preventable. That's what the research is showing and what Parkinson's expert and advocate Dr Ray Dorsey is on a mission to communicate to the world. Parkinson's disease is the downstream effect of the indiscriminate, criminal and unnecessary use of neurotoxic chemicals we are spraying on our food, spraying on our sport fields, using in our dry-cleaning and breathing in the air. Dr. Ray Dorsey is a neurologist, researcher, and internationally recognized leader in Parkinson's disease care, prevention, and health-care innovation. He holds a BS from Stanford University and a joint MD/MBA from the University of Pennsylvania (Perelman School of Medicine and Wharton). Currently, Dr. Dorsey is a practicing neurologist at Atria and Director of Atria's Center for the Brain & the Environment, a nonprofit research initiative focused on identifying and preventing environmental causes of neurodegenerative disease, including Parkinson's and Alzheimer's. He has authored more than 200 peer-reviewed publications, raised over $60 million in research funding, and was honored at the White House as a Champion of Change. A leading voice for prevention-focused medicine, he is the author of Ending Parkinson's Disease and the forthcoming The Parkinson's Plan, and remains committed to reimagining how brain health is protected across the lifespan.Knowledge is power. Learn how we are going to stop Parkinson's with Dr Dorsey's books: www.pdplan.orgContact:Website - www.pdplan.orgInstagram - @raydorseymd Join us as we explore:How Parkinson's exploded from 6 to 6 million cases in just a few centuries, Why Parkinson's is all about the chemicals in our food, water and air, NOT GENETICS and is a PREVENTABLE disease.How to live well despite a Parkinson's diagnosis, the danger of golf courses and the most dangerous Parkinson's chemicals.The link to the microbiome and predictive diagnostics techniques using data science and AI.Mentions:Person - Dr Caroline Tanner, https://www.michaeljfox.org/researcher/caroline-tanner-md-phd Book - Silent Spring, https://en.wikipedia.org/wiki/Silent_SpringOrganization - Atria, https://www.atria.orgSupport the showFollow Steve's socials: Instagram | LinkedIn | YouTube | Facebook | Twitter | TikTokSupport the show on Patreon:As much as we love doing it, there are costs involved and any contribution will allow us to keep going and keep finding the best guests in the world to share their health expertise with you. I'd be grateful and feel so blessed by your support: https://www.patreon.com/MadeToThriveShowSend me a WhatsApp to +27 64 871 0308. Disclaimer: Please see the link for our disclaimer policy for all of our content: https://madetothrive.co.za/terms-and-conditions-and-privacy-policy/
Episode 350 What If Alzheimer's disease starts in the body, not the brain? A radical new theory upends everything we thought we knew about the disease. Alzheimer's is the most common form of dementia - the leading cause of death in the UK. And for 100 years we believed it all happened in the brain. Despite all of the major symptoms of Alzheimer's being brain related, scientists studying gene activity have discovered something surprising. Most risk variants for the disease appear in the skin, lungs and gut - not the brain. This could mean the leading suspects of the disease - amyloid plaques and tau proteins - may not be to blame. But if not them, then what? Rowan Hooper is joined by New Scientist's Australia reporter Alice Klein to discuss the findings. Chapters (00:00) Intro - A radical new understanding of Alzheimer's (01:23) Why amyloid and tau treatments aren't proving effective (02:16) How gum and dental health is linked to Alzheimer's (03:09) Could proteins in the brain be a protective feature? (03:56) Why amyloid and tau really aren't the full picture (04:35) Why scientists have gone back to the drawing board (05:37) Does Alzheimer's start in the skin, lungs and gut? (06:14) Alzheimer's risk genes found in the immune system and barrier tissues (07:12) Where inflammation fits into the puzzle of Alzheimer's (09:10) The role of the blood brain barrier (10:00) How have scientists responded to these findings? (10:58) What other health conditions are linked to Alzheimer's? (12:08) Preventative measures you can take to reduce your Alzheimer's risk (15:03) How reframing diseases leads to better treatments To read more about these stories, visit https://www.newscientist.com/ Read the latest New Scientist CoLab article: https://newscientist.com/eternal Learn more about your ad choices. Visit megaphone.fm/adchoices
Tips for travelers making spring, summer plans With spring break here and the peak summer travel season approaching, a whopping 90% or more of Americans say they plan to travel for vacation this year. But travel planning is being complicated by uncertainty due to several factors including current global instability due to the war in the Middle East.That conflict has led to a spike in oil prices impacting flight fares and gas prices. The ongoing partial government shutdown has also led to longer wait times for security lines as the Transportation Security Administration deals with staffing shortages. TSA workers are currently being asked to work without pay. Links mentioned in the discussion State Dept. Travel Advisories STEP Program from the U.S. Dept. of State CDC Travel Advisories CDC Polio Global Health Advisory We begin the show on Wednesday with travel experts to talk about the current stressors on the travel market and answer questions you may have if you have travel plans. Guests: - Phil Ridolfi, Owner, The Exceptional Traveler - Zach Wichter, Consumer Travel Reporter at USA Today Could research into animal Alzheimer's help humans? Alzheimer's Disease affects around 7 million Americans and is the sixth-leading cause of death in the US. It's a very real consequence of humans' long lives compared to other animals. But other animals, like dogs, cats, pigs and chimpanzees can get Alzheimer's and researchers are studying how it affects them. Today we'll hear a discussion about how the Alzheimer's affects chimpanzees and how that can help treat humans. Plus, we'll learn about lifestyle changes that can help reduce the risk of Alzheimer's Disease. Guests: - Jeff St. Clair, Host, Ideastream Public Media - Takhar Kasumov, Ph.D., School of Biomedical Sciences, Kent State University - Melissa Edler, Ph.D., Assistant Professor - Anthropology, Kent State University
All Home Care Matters and our host, Lance A. Slatton were honored to welcome Dr. Dale V. Atkins as guest to the show. About Dr. Dale V. Atkins: Dale V. Atkins, Ph.D., is a licensed psychologist and educator with more than forty-five years of experience working with individuals, couples, and families. Dr. Atkins consults domestically and internationally. She conducts seminars and retreats for health and educational institutions, executives and employees of major corporations, and government agencies in matters related to the fields of psychology, sociology, education, and communication. She practices, teaches, and consults in the field of Alzheimer's and Related Disorders with a focus on prevention as well as patient and caregiver wellness and resilience. She emphasizes the benefits of intergenerational relationships in families and communities. Dr. Atkins values opportunities to share everyday human stories with those in the health care field. She is the author of eight books; most recently, The Turquoise Butterfly, (her first children's book), chapters, articles, and journals for popular and professional audiences. For 22 years Dr. Atkins was a recurring guest expert on NBC's "Today" show. Dr. Atkins is an active volunteer in her community. She and her dog are a certified dog therapy team who have participated in school readers' programs as well as visitation programs at day and residential facilities for people who have Alzheimer's. She is a member of several non-profit boards whose focus is literacy, tolerance, women's health and wellness, child protection, hospital leadership, and community action. An engaged citizen, she has received multiple recognitions for her community service and leadership. Dr. Atkins has two children and six grandchildren. She has private practice in NYC and lives in CT, where she is often found outdoors.
Zone two has been sold to you as the gold standard for mitochondrial health, fat burning, and longevity. But what if it was built on culture, not science. In this episode, I sit down with Kristi Storoschuk, a PhD researcher whose work is challenging some of the biggest claims in the exercise world right now. We break down why zone two training lacks the scientific evidence everyone assumes it has, why higher intensity zones three and four are actually more potent for mitochondrial adaptation, and why the 80/20 training split from elite athletes was never designed for someone exercising four days a week. We also get into why fasting doesn't activate the same cellular pathways in humans as it does in rodents, why cortisol from exercise is not the same as chronic stress, the truth about fasted exercise for women, and what lactate actually tells us about our metabolic health. Kristi also shares her current research in collaboration with Dr. Andy Galpin and Dr. Tommy Wood on whether lactate threshold can serve as a non-invasive proxy for mitochondrial content. This conversation will completely change how you think about every cardio session you've ever done. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: Was Zone Two Built on Culture, Not Science? 03:19 The Three Exercise Intensity Domains (Not Five Zones) 08:00 Zone Two and Fat Burning: What the Research Actually Shows 12:00 Why Women Are Being Scared Away from Zone Three and Four 20:45 Fasting in Rodents vs. Humans: The Research That Changed Everything 24:00 Fasted Exercise and Cortisol: The Real Story for Women 29:00 What Lactate Actually Tells Us About Mitochondrial Health 37:00 VO2 Max, Mitochondria, and Longevity 43:30 Exercise as Your Daily Metabolic Reset 49:00 The Best Cardio Prescription for Healthspan 55:30 How a 73 Year Old Should Think About High Intensity 58:00 How to Know What Zone You're In Without a Monitor 01:02:00 Sex Differences in Exercise: What the Data Actually Says _______ Thank you to our sponsors Function health: https://www.functionhealth.com/louisanicola Timeline: http://timeline.com/NEURO Jones Road Beauty: https://www.jonesroadbeauty.com And Use code NEURO Lifeboost coffee : https://lifeboostcoffee.com/ and Use code NEURO for 10% off Just Thrive: https://justthrivehealth.com/NEURO _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
Do you have a loved one suffering from dementia, and have you started noticing a few worrying signs of it in yourself? Maybe it's not you, but others around you who have noticed…and that's concerning you more than you want to admit. Either way, you know you want to stay as mentally sharp and alert as you can, for as long as possible. So do we just sit and wait, hoping that our minds won't fail too quickly and badly? Or is there something we can to do to slow down or prevent rapid mental decline, by changing the foods on our plates? Let's talk about this. In this episode, we'll see how eating differently – specifically adding in more fiber-rich plant-based foods to our meals – can help build a stronger, more mentally active brain and even cut dementia risk. I want to share some fascinating research that has emerged linking the fiber content of our diets and the risk of dementia. So if you want to stay mentally sharp and cognitively active for longer, join me in this episode. Let's go! Contact -> healthnow@plantnourished.com Learn -> www.plantnourished.com Join -> Plant-Powered Life Transformation Course: www.plantnourished.com/ppltcourse Enjoy 1:1 Coaching Support -> https://www.plantnourished.com/coachingwaitlist Get Free 15-Minute Strategy Call -> www.plantnourished.com/strategycall Free Resource -> 7 Ways to Test-Drive a Plant-Based Diet: www.plantnourished.com/testdrive Have a question about plant-based diets that you would like answered on the Plant Based Eating Made Easy Podcast? Send it by email (healthnow@plantnourished.com) or submit it by a voice message here: www.speakpipe.com/plantnourished [Plant Based Nutrition, Dementia, Brain Health, Plant Based Eating, Whole Foods, Alzheimers Disease, Mental Health, Aging Well, Cognitive Health, Memory Loss]
Register for a live Q&A with Dr. Tommy Wood on Wednesday, March 25th.Decreased glucose uptake in the brain is often considered a hallmark of Alzheimer's disease. But Dr. Tommy Wood asks whether part of that metabolic signature may reflect how little cognitive demand we place on the brain.He sits down with Dr. Dominic D'Agostino for a nuanced conversation on metabolic health and cognitive function.. Dr. Wood is a neuroscientist, neonatal brain injury researcher, and author of The Stimulated Mind.This episode follows the metabolic thread through every stage of brain health. Pre-diabetes and type 2 diabetes as predictors of cognitive decline. Neurovascular coupling as the reason heart disease risk factors double as brain disease risk factors. Lactate crossing the blood-brain barrier to drive BDNF production where it actually matters. Creatine as a brain energy distributor that most people still only associate with muscle. Dr. Wood lays out his Three S Model — Stimulus, Supply, Support — and makes the case that cognitive demand drives glucose uptake into the brain the same way muscular contraction drives it into skeletal muscle.Questions Answered in This Episode:Does the brain respond to energy demand the same way skeletal muscle does?What role does creatine play in brain energy distribution, and what do the clinical trials show?Can heavy resistance training produce the same brain-relevant lactate response as HIIT?How should exercise be dosed after a concussion or traumatic brain injury?Is cognitive decline in your 50s, 60s, and 70s actually inevitable, or is that a statistical artifact?Why are pre-diabetes and metabolic syndrome among the strongest predictors of dementia?The mechanistic throughline here is demand-driven metabolism. Dr. Wood makes the case that the same principles governing glucose uptake in skeletal muscle apply to the brain — and the conversation gets into what that means for how we interpret FDG-PET data, design lifestyle interventions, and think about neurodegeneration itself.Find more at DrTommyWood.comSpecial thanks to the sponsors of this episode:✅ Fatty15 – Get 15% off a 90-day Starter Kit with code METABOLICLINK here✅ Troscriptions – Get 10% off your first order with code METABOLICLINK here✅ Toups and Co – Get 15% off your first order with code METABOLIC here✅ ZocDoc - Find and instantly book a top-rated doctor hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
Are you a researcher interested in getting involved in Alzheimer's disease and related dementias (ADRD) clinical trials? The Institute on Methods and Protocols for Advancement of Clinical Trials in ADRD, or IMPACT-AD, program brings investigators from around the world together for a week of professional development and education. IMPACT-AD co-directors Dr. Josh Grill and Dr. Rema Raman, as well as faculty member Dr. Maria Carrillo, join the podcast to explain what the program entails, their mission and more. Guests: Josh Grill, PhD, director, Institute for Memory Impairments and Neurological Disorders, professor, University of California, Irvine (UCI), co-director, IMPACT-AD, Rema Raman, PhD, co-director, IMPACT-AD, director, Biostatistics Section and Recruitment, Engagement, and Retention Section, Alzheimer's Therapeutic Research Institute (ATRI), professor of neurology, University of Southern California (USC), and Maria Carrillo, PhD, chief science officer, medical affairs lead, Alzheimer's Association, co-principal investigator, Alzheimer's Network for Treatment and Diagnostics (ALZ-NET), co-principal investigator, Longitudinal Early-Onset Alzheimer's Disease Study (LEADS) Show Notes Learn more and apply for the 2026 IMPACT-AD program on their website. Listen to our previous episode with Rema Raman, “Making an IMPACT: Advancing Alzheimer's Disease Clinical Trials Through Workforce Development and Inclusivity,” on our website, Spotify, Apple Podcasts and wherever you listen. Listen to our previous episodes with Josh Grill, “The Case for Disclosing Biomarker Results to Alzheimer's Research Participants” and “Improving Registries and Representation in Alzheimer's Disease Research” on our website. Read more about Dr. Raman in her USC Keck School of Medicine Profile. Read more about Dr. Grill in his UCI faculty profile. Read more about Dr. Carrillo on the Alzheimer's Association website. Connect with us Find transcripts and more at our website. Email Dementia Matters: dementiamatters@medicine.wisc.edu Follow us on Facebook and Twitter. Subscribe to the Wisconsin Alzheimer's Disease Research Center's e-newsletter. Enjoy Dementia Matters? Consider making a gift to the Dementia Matters fund through the UW Initiative to End Alzheimer's. All donations go toward outreach and production. Learn about and pre-order Dr. Chin's book, When Memory Fades: What to Expect at Every Stage, from Early Signs to Full Support for Alzheimer's and Dementia, out June 2, 2026.
This week on Dentistry Unmasked, we cover Brian's all-time favorite topic… saliva. Pam and Brian sit down with Dr. Paul Slowey—the innovator behind many of the salivary diagnostic tests transforming health care today. He's the mind behind cutting-edge saliva tests, including the one used by the NFL to help determine whether a player has suffered a concussion. But that's just the beginning. What if we told you that Alzheimer's disease can be detected in saliva up to 10 years before clinical symptoms appear? The implications for dentistry—and for health care as a whole—are staggering. In this episode, you'll discover: • How salivary diagnostics are changing medicine and dentistry • Why saliva may be the most underutilized diagnostic tool in health care • The science behind concussion testing through saliva • What early Alzheimer's detection could mean for patients and practices • Why the future of precision health may start in the dental chair Salivary diagnostics isn't just “the future”—it's already here. If you've ever wondered how dentistry fits into the larger medical landscape, this episode will change the way you see the power of a simple saliva sample. Trust us—Brian is excited about this one and you will be too! Resources: pds@4saliva.com Dr.Paul Slowey
Forever Young Radio Show with America's Natural Doctor Podcast
Topic: Newly Published Kyolic Aged Garlic Extract Study on Global Cognitive Health.Joining us today is Jane Jansen, a Natural & Holistic Practitioner at The Tree of Life Wellness Center in Massachusetts. Jane has the unique perspective as a medical professional who, prior to becoming a natural & holistic practitioner, spent years in Radiology and Ultrasound doing research and performing tests on patients with varying types of health problems including cardiovascular. Jane joins us to discuss a very exciting, NEWLY published study that shows that Kyolic Aged Garlic Extract enhances cognition by increasing Nitric Oxide.According to The Alzheimer's Association, an estimated 7.2 million Americans, age 65 and older, are currently living with Alzheimer's disease.While science continues to search for a medical breakthrough to effectively address this devastating brain condition, a growing number of studies point to the role non-pharmaceuticals can play in improving cognition and possibly even helping to keep Alzheimer's at bay. One of those garnering interests is nitric oxide, a colorless gas primarily produced within the endothelial cells lining the body's blood vessels.Promising research shows that nitric oxide (NO) can help improve cognition and protect against dementia by enhancing neuronal communication, reducing inflammation, and supporting healthy blood flow in the brain. It also supports the brain's ability to adapt and form new connections—a process vital for learning new things and storing memories. The problem is, the body's production of NO declines with age, with a loss of up to 75 percent by age 70. What's more, epidemiological investigations have found a link between this deficiency and Alzheimer's disease in the elderly.A new study in the World Academy of Sciences Journal reports that AGE can effectively enhance cognition by increasing NO's bioavailability.Kyolic AGE is the best-selling, odorless, aged garlic extract. Proven safe and effective, AGE and its constituents have been the subject of over 1000 published scientific articles that document its health benefits.Kyolic Aged Garlic Extract formulas are available at your local health food store and online. For more information about Kyolic, or to find a retailer near you, visit Kyolic.com
Brain Talk | Being Patient for Alzheimer's & dementia patients & caregivers
Dr. Michael Fossel, MD, PhD is a physician-scientist and recognized expert in aging and telomere biology. He serves as chairman of the board of Telocyte, a biotech company developing telomerase therapy for Alzheimer's disease, with FDA-sponsored human trials planned to target the underlying disease process. Fossel has authored more than 100 scientific publications and has lectured internationally, including at the National Institutes of Health. His work explores how processes like cell senescence — when aging cells stop working properly and can contribute to chronic inflammation — may help drive age-related diseases, including Alzheimer's.In the interview with Being Patient Founder Deborah Kan, Fossel argues that aging is not simply wear and tear, but a breakdown in the body's ability to maintain and repair cells over time. He explains why lifestyle habits may help slow aging but are unlikely to reset it and outlines why his research is focused on whether telomerase therapy could restore cellular function in Alzheimer's. He acknowledges that the science is still in its early stages, with major questions remaining about how much damage can be reversed, which patients might benefit most, and how soon these ideas can be tested in people.----If you loved listening to this Live Talk, visit our website to find more of our Alzheimer's coverage and subscribe to our newsletter: https://www.beingpatient.com/Follow Being Patient: Twitter: / being_patient_ Instagram: / beingpatientvoices Facebook: / beingpatientalzheimers LinkedIn: / being-patient Being Patient is an editorially independent journalism outlet for news and reporting about brain health, cognitive science, and neurodegenerative diseases. In our Live Talk series on Facebook, former Wall Street Journal Editor and founder of Being Patient, Deborah Kan, interviews brain health experts and people living with dementia. Check out our latest Live Talks: https://beingpatient.com/live-talks/
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Explore 30–200 root causes of Alzheimer's including sleep, inflammation, ApoE4, and lifestyle habits that either prevent or accelerate cognitive decline. #AlzheimersCauses #Inflammation #GeneticsAndLifestyle #CognitiveCare
If you want to get leaner and live longer check out https://milliondollarbodylabs.com Are you wasting money on "miracle" supplements while ignoring the simple habits that actually build muscle, protect your brain, and help you live longer? I talk with Alex Jamal. We discuss fitness. Alex explains bodybuilding. I ask about peptides. We cover health. We talk about supplements. Alex mentions creatine. We discuss brain function. We talk about sleep. Alex shares thoughts on amino acids. I mention my experiment with leucine. We talk about pre-workout drinks. We discuss blood flow. I share my experience using baking soda. We focus on consistency. Alex describes her background. We provide a guide for people. Key Takeaways Peptides and unverified supplements often lack long-term data and third-party testing, making them risky compared to established options. Creatine provides significant benefits for brain health and may reduce the risk of dementia or Alzheimer's. Essential Amino Acids (EAAs) are more effective for muscle protein synthesis than taking branched-chain amino acids (BCAAs) or leucine alone. Sleep is a highly underrated factor for muscle recovery and hormonal health, especially for men. Stimulant-free pre-workouts allow for better blood flow (vasodilation) compared to high-caffeine options that constrict vessels. Baking soda (sodium bicarbonate) can increase endurance by about 30% during high-intensity isometric or endurance activities, but requires careful dosing to avoid digestive issues. Consistency for at least six to eight weeks is necessary to see real physiological changes in the body. Resources Business Website: https://www.fitnessresultscoach.com Business Instagram: @fitnessresultscoach Alex Jamal's Instagram: @thetraineralex Guest LinkedIn: https://www.linkedin.com/in/alex-jamal-45755626 Nate Palmer: The founder of The Million Dollar Body and author of "The Million Dollar Body Method", Nate has been coaching for over 15 years and has worked personally with over 1,000 clients. Website: https://milliondollarbodylabs.com Book: The Million Dollar Body Method Lean Energy Stack: https://milliondollarbodylabs.com/pages/lean Instagram: @_milliondollarbody
Forget the bubble-bath checklist. We dig into a practical, body-first approach to caregiver self-care that actually holds under pressure: better sleep, objective stress data, scaled movement, protected solitude, and preventive health that keeps you in the game. I share how a therapist's tough wake-up call led me to a sleep study, what “daytime sleepiness” really means on the road, and how an oral appliance changed my oxygen, sleep quality, and mornings. We explore why you can feel exhausted after a “full night” and what it takes to make sleep count when you're balancing the relentless demands of caregiving.From there, we talk tools that don't hijack your attention. The Oura Ring has been a quiet revolution for tracking sleep stages, HRV, and recovery without another screen buzzing on your wrist. Seeing stress in numbers helped me shift workouts, add breathwork, and take short walks that actually bring my system down rather than push it over the edge. Movement becomes strategic: on good days, run or lift; on strained days, yoga, stretching, or a slow ride. Ten minutes can change the tone of an entire afternoon.We also get honest about solitude. As an introvert in a loud, hands-on role, scheduled quiet time is non-negotiable. Thirty minutes in a dark room, no texts, no talk, can reset a nervous system that's been on high alert for years. And we round it out with annual checkups, lab work, mammograms, and eye exams—the dashboard lights for the most important machine you own. The theme is simple: personalize your self-care to your body's weak links, measure what matters, and treat maintenance like mission-critical safety. If you've ever felt unseen by generic advice, this conversation hands you a tighter, smarter playbook.If this helped, subscribe, share it with a caregiver who needs backup, and leave a review so more folks can find us. Your story might be the nudge someone else needs.Support the show"Alzheimer's is heavy but we ain't gotta be!"IG: https://www.instagram.com/parentingupFB: https://www.facebook.com/parentingupYT: https://www.youtube.com/@parentingupTEXT 'PODCAST" to +1 404 737 1449 - to give J topic ideas, feedback, say hi!Be sure to leave us a review!
What if Alzheimer's, multiple sclerosis, chronic fatigue, and even psychiatric symptoms are not random but driven by hidden infections? In this episode of Integrative Lyme Solutions, Dr. K sits down with research scientist and Lyme survivor Nikki Schultek to explore the infection hypothesis behind chronic disease. After battling years of misdiagnosed symptoms including asthma flares, interstitial cystitis, arrhythmias, neurological decline, and suspected MS, Nikki uncovered a complex web of infections including Borrelia, Bartonella, Babesia, Chlamydia pneumoniae, Epstein-Barr virus, and more. Now founder of the Alzheimer's Pathobiome Initiative, Nikki is leading a global consortium investigating how stealth pathogens may trigger neurodegeneration, immune dysfunction, and dementia. This conversation dives into intracellular infections, the Herxheimer reaction, amyloid as an antimicrobial response, sterile brain autopsies, precision medicine, and why federal health agencies are finally acknowledging Lyme disease as a serious public health crisis. If you or someone you love is dealing with chronic Lyme, long COVID, autoimmune illness, or cognitive decline, this episode may change how you see disease. Key Takeaways: 0:00 Introduction 3:15 Asthma, air hunger, and early misdiagnoses 8:40 From interstitial cystitis to suspected multiple sclerosis 14:30 Discovering intracellular infections and Chlamydia pneumoniae 18:45 Lyme, Bartonella, Babesia and the whack-a-mole effect 24:10 The Pathobiome concept and microbial imbalance 27:30 Alzheimer's disease and the infection hypothesis 32:00 Sterile brain autopsies and spinal fluid research 35:20 Amyloid plaque as an antimicrobial defense mechanism 41:00 APOE4, genetics, and infection susceptibility 44:30 Federal recognition of Lyme disease and future funding Resources Mentioned: Alzheimer's Pathobiome Initiative - https://alzheimerspathobiome.org ILADS - https://www.ilads.org ILADS Education Foundation - https://www.iladef.org Philadelphia College of Osteopathic Medicine - https://www.pcom.edu Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. _______________________________The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor at The Karlfeldt Center, call 208-338-8902 or email info@TheKarlfeldtCenter.comCheck out Dr. K's Ebook: Breaking Free From Lyme: A Comprehensive Guide to Healing and Recovery here: https://store.thekarlfeldtcenter.com/products/breaking-free-from-lymeUse the code LYMEPODCAST for a 100% off discount!
What happens when one of the world's most technically trained medical specialists begins questioning the deeper nature of consciousness, healing, and the human operating system? In this fascinating conversation, Darin sits down with renowned neurosurgeon Dr. Amir Vokshoor, whose work sits at the intersection of cutting-edge brain surgery, regenerative medicine, mindfulness, and the philosophy of consciousness. From performing delicate brain and spine surgeries to creating a "Brain Spa" focused on nervous system healing, Dr. Vokshoor explores how modern medicine is beginning to merge with ancient wisdom, emerging technologies, and a deeper understanding of the human mind. Together they unpack the future of spine medicine, stem cells, psychedelics, meditation, chronic pain, consciousness, and why collaboration across disciplines may be the only way to truly understand the brain. This episode explores one of the most fascinating questions in modern science: How much of our health—and even our identity—is shaped by the stories our brain tells us? What You'll Learn Why neurosurgical training is one of the most demanding disciplines in medicine and how it shapes the psychology of surgeons The pivotal moments that changed Dr. Amir Vokshoor's view of medicine, including witnessing his father's battle with Alzheimer's Why modern healthcare often focuses on treating symptoms instead of understanding the root causes of neurological disease How the brain, gut, immune system, and environment work together as an integrated "grander nervous system" The science behind chronic pain and why it often becomes a brain-based condition rather than just a structural injury How regenerative medicine, including PRP, stem cells, and exosomes, is transforming the future of spine care Why back pain is the most disabling condition in the world and how new surgical technologies are changing treatment The role of mindfulness, visualization, and intention in surgical performance and patient healing How psychedelics and therapies like ketamine are opening new pathways for treating trauma, depression, and chronic pain Why our thoughts, beliefs, and repeated mental patterns may shape not only our behavior, but our long-term health and identity Chapters 00:00:00 – Welcome to the SuperLife podcast and the mission of health sovereignty 00:00:33 – The exploding NAD market and why supplement transparency matters 00:02:17 – Introducing Dr. Amir Vokshoor and the philosophical side of neurosurgery 00:03:09 – How surgical training shapes personality through fear-based risk avoidance 00:04:22 – The intense demands and physical toll of neurosurgical training 00:05:38 – Why neurosurgery training often feels like medical "boot camp" 00:06:01 – The psychological transformation that happens during residency 00:06:33 – The moment a surgeon removes their first brain tumor 00:07:03 – Why the brain remains the most complex operating system known 00:07:31 – How humanity's view of the brain has evolved with technology 00:07:53 – The coming era of AI-enhanced human consciousness 00:08:22 – How humans may adapt to the technological singularity 00:08:47 – Can we code empathy and ethics into artificial intelligence? 00:09:31 – A fascinating study comparing empathy from AI versus human doctors 00:09:49 – Darin shares a frightening medical emergency involving his mother 00:10:36 – The importance of empathy in medical communication 00:11:00 – Why emotional intelligence may be as important as technical skill in medicine 00:11:27 – The harsh realities of physician burnout and shortened life expectancy 00:11:56 – A pivotal leadership moment inside the operating room 00:12:20 – Learning to lead through calmness rather than fear 00:13:20 – Viewing difficult moments in medicine as teachable experiences 00:13:47 – The moment Dr. Vokshoor's father developed Alzheimer's 00:14:13 – How neuroscience led him toward meditation and Buddhist philosophy 00:14:33 – The concept that our perceived reality may be a neurological construct 00:15:03 – How sensory inputs create the illusion of a stable reality 00:15:31 – Why loosening our grip on reality can open philosophical insight 00:16:13 – The limits of reductionist medicine 00:16:35 – The need to understand the root causes behind disease 00:16:55 – The fear surgeons have about becoming "too emotional" 00:17:20 – Why humanity and technical precision can coexist in surgery 00:17:58 – The use of mindfulness and visualization before surgery 00:18:25 – Lessons surgeons can learn from Olympic visualization techniques 00:18:48 – Intentionality and mental preparation before entering surgery 00:19:09 – Sponsor message: Fatty15 and cellular health 00:22:50 – How mindfulness enhances focus rather than interfering with surgery 00:23:16 – The concept of increasing "gain" in the nervous system 00:23:38 – The role of intention in healing and recovery 00:24:01 – Preparing patients mentally before surgery 00:24:25 – The mysterious healing power of belief and prayer 00:24:55 – Why surgery is partly artistic, not just technical 00:25:29 – The hidden role of creativity and art in science 00:26:25 – How AI could free humans to focus more on empathy and intuition 00:26:53 – Why modern medicine often stops caring once the surgery ends 00:27:10 – The need to support long-term neurological healing 00:27:32 – The connection between brain healing, gut health, and immunity 00:28:30 – How reductionist medicine became dominant in Western healthcare 00:29:16 – Doctors as their own "energy managers" through caffeine and glucose 00:30:05 – The confusion and controversy surrounding nutrition science 00:31:08 – The massive scientific focus on the amyloid hypothesis in Alzheimer's 00:31:32 – Billions spent on Alzheimer's treatments that ultimately failed 00:31:52 – The concept of "final common pathways" in neurological disease 00:32:17 – Darin shares his personal experience with chronic spinal injury 00:32:45 – PRP therapy and early regenerative treatments 00:33:07 – Stem cell therapy and regenerative medicine 00:33:32 – Culturing stem cells and emerging regenerative technologies 00:34:18 – The Wild West phase of stem cell medicine 00:35:02 – The risks of poorly regulated regenerative therapies 00:35:40 – Bone marrow stem cell injections for spinal repair 00:36:21 – Darin jokingly talks to his stem cells before injection 00:36:47 – The brutal reality of living with chronic pain 00:37:18 – Patreon message: building a conscious global community 00:38:22 – Regenerative medicine and the future of spinal repair 00:38:40 – Photobiomodulation and red-light therapy for healing 00:39:07 – Advances in artificial discs and spine surgery 00:39:51 – Why back pain is the most disabling condition in the world 00:40:26 – Motion-preserving spine surgery replacing fusion procedures 00:41:05 – The revolutionary potential of artificial facet joints 00:41:29 – Why spinal health determines long-term mobility and independence 00:42:00 – Replacing entire spinal motion segments 00:42:24 – The regulatory and financial barriers to new surgical technology 00:43:08 – Building interdisciplinary research teams to study the nervous system 00:43:35 – The concept of the "Grander Nervous System" 00:44:15 – The financial realities doctors face within the healthcare system 00:44:54 – Building independent research networks outside universities 00:45:20 – Why collaboration between disciplines is critical for progress 00:46:01 – Indigenous knowledge informing modern environmental science 00:46:34 – Collaboration as a catalyst for scientific breakthroughs 00:47:12 – Why ego and hierarchy often slow down scientific progress 00:48:04 – Balancing ego, leadership, and humility in medicine 00:49:05 – The importance of legacy and purpose in shaping one's career 00:49:51 – The concept of "Room Zero vs Room One" for mental training 00:50:18 – Meditation styles that train different brain states 00:51:24 – Psychedelics and the neuroscience of ego dissolution 00:51:45 – The danger of skipping the hard inner work 00:52:20 – Ketamine therapy for chronic pain and trauma 00:52:42 – Powerful transformations seen in psychedelic-assisted therapy 00:53:14 – Chronic pain as a brain-based disease 00:53:38 – The danger of treating structural problems while ignoring psychology 00:54:09 – Fear and avoidance patterns after chronic injury 00:54:37 – Habituation and the nervous system's adaptation to pain 00:55:21 – When illness becomes part of a person's identity 00:56:18 – The idea that the body may never make mistakes 00:57:17 – Tracing root causes behind disease expression 00:58:07 – The philosophical possibility that life events happen for us, not to us 00:58:53 – Mid-episode break and behind-the-scenes conversation 01:00:03 – Reflections on Darin's global travel and filmmaking work 01:02:58 – Dr. Vokshoor's idea for a book about thinking 01:03:29 – The brain's biological function of generating thoughts 01:04:15 – Training the mind the same way we train the body 01:05:13 – Are thoughts signals we receive rather than create? 01:06:06 – Why the brain constantly seeks stimulation and dopamine 01:07:03 – Meditation and psychedelics as tools to reset mental patterns 01:07:54 – How belief systems shape habits, behaviors, and identity 01:08:00 – The possibility that the human nervous system may interact with Earth's electromagnetic fields and the Schumann resonance 01:08:47 – The role of geomagnetic frequencies in brainwave activity and human physiology 01:09:30 – Could the brain be receiving environmental signals rather than generating everything internally? 01:10:12 – The relationship between alpha and theta brainwave states and grounding 01:11:05 – How modern technology and artificial environments may disrupt natural neurological rhythms 01:12:00 – The importance of reconnecting the nervous system with nature and environmental inputs 01:13:15 – How modern lifestyles disconnect the brain from the biological signals it evolved with 01:14:30 – The growing scientific curiosity around bioelectromagnetics and consciousness 01:15:40 – Why the nervous system may function more like a receiver than a generator 01:16:45 – Philosophical implications of consciousness interacting with the environment 01:18:00 – The mystery of where thoughts originate and how the brain processes information 01:19:20 – Why the brain constantly seeks stimulation, novelty, and dopamine 01:20:30 – The addictive loop created by modern digital environments and endless information 01:21:45 – How mindfulness practices interrupt the rumination cycle 01:22:50 – Rewriting mental patterns through intentional thought and belief 01:23:55 – The powerful relationship between belief systems and nervous system regulation 01:24:50 – Why habits ultimately shape identity and long-term health 01:25:40 – The importance of repeating thoughts and behaviors that move life toward a meaningful direction 01:26:20 – Final reflections on consciousness, healing, and evolving the human operating system 01:27:00 – Closing thoughts and wrap-up of the conversation with Dr. Amir Vokshoor Thank You to Our Sponsors Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Truniagen: Go to www.truniagen.com and use code DARIN20 at checkout for 20% off Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Find More from Dr. Amir Vokshoor Website:drvokshoor.com Instagram: @drvokshoor Neurovella Brain Spa: https://www.neurovella.com/ Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Key Takeaway The brain may be the most complex structure in the known universe — but understanding it requires more than reductionism. It requires humility, collaboration, and the courage to explore both the mechanical and the mystical dimensions of being human.
According to the Alzheimer's Association, nearly seven million Americans currently suffer from that type of dementia. Experts expect that more will be burdened with it in the future, as baby boomers continue to reach advanced ages. Many people are eager to protect the brain from deterioration. In this episode, we discuss an unexpected approach to […]
Watch every episode ad-free & uncensored on Patreon: https://patreon.com/dannyjones Mario Beauregard, PhD, is a cognitive neuroscientist who studies the neuroscience of consciousness and mystical experience, including a study investigating the brain activity of Carmelite nuns. He is co-author of the book 'The Spiritual Brain: A Neuroscientist's Case for the Existence of the Soul'. SPONSORS http://amentara.com/go/dj - Use code DJ22 for 22% off. https://rag-bone.com - Use code DANNY & get 20% off sitewide. https://capl.onelink.me/vFut/zralgyl0 - Download CashApp today! https://chubbiesshorts.com/danny - Use code DANNY for 20% off. https://whiterabbitenergy.com/?ref=DJP - Use code DJP for 20% off EPISODE LINKS The Spiritual Brain - https://a.co/d/0cZDv6gn https://www.drmariobeauregard.com FOLLOW DANNY JONES https://www.instagram.com/dannyjones https://twitter.com/jonesdanny OUTLINE 00:00 - Dr. Beureguard's childhood mystical experience 03:52 - Discovering everything is connected as one 07:08 - Mario "downloaded" his life's mission 09:54 - Mario's failed journey to become a priest 15:44 - Mario's second mystical experience 21:08 - What Mario saw in Heaven 23:30 - Mario's biological markers say he's 20 years younger 29:19 - How Mario became a neuroscientist 30:07 - The roots of modern science 31:02 - When science lost its spiritual connection 34:27 - Testing memory molecules for Pfizer 36:00 - Pfizer pushed ineffective Alzheimer's drug in 1994 41:12 - Why Mario fled Canada during the pandemic 43:00 - Justin Trudeau paid off court judges during the pandemic 46:31 - The Catholic Church tried to bribe Mario 53:38 - Why the church is pushing new science 01:01:10 - Carmelite nuns study 01:07:00 - 1% of seizures trigger mystical experiences 01:09:57 - Johns Hopkins psychedelics + religion study 01:13:07 - Mario tested all drugs before experimenting 01:14:44 - Human psyche vs. consciousness 01:16:55 - "Consciousness" is the scientific God 01:21:56 - Non-physical information 01:25:17 - Where thoughts come from 01:30:14 - Holotropic breathwork to expand consciousness 01:34:58 - New consciousness research 01:38:02 - Who's funding consciousness research 01:40:11 - Studies on people who survived death 01:44:58 - Holosynthesis 01:49:33 - What happens when you "overdose" psychedelics 01:52:20 - Church-sanctioned psychedelic use 01:55:57 - Humans are behaving like robots 02:02:54 - Joan Jett's spiritual transformation 02:05:37 - NDEs vs. life reviews 02:07:21 - Memories of past lives 02:15:35 - How to expand consciousness using sound 02:21:30 - Bufo: DMT times 1,000 02:24:39 - Mapping neurological effects across religions 02:26:25 - The Dalai Lama's lesson on attention 02:32:04 - What the brains of uncontacted tribes might look like 02:37:55 - Explanation of the universe Learn more about your ad choices. Visit podcastchoices.com/adchoices
Microplastics are invading your brain, blood, hormones, and fat tissue, and most people have no idea how deep the damage goes. In this episode, Host Dave Asprey and microplastics expert Josephine Musco break down exactly what these particles are doing inside your body and give you a practical, science-backed action plan to detox, protect yourself, and take back control of your biology. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Get a discount on Olyxir Tea by going to https://www.olyxir.com/ and using code ‘Dave10' at checkout Josephine Musco is a multidisciplinary entrepreneur, Demeter-certified biodynamic farmer, and winemaker at Chateau Bellevue 1881 in Livermore, California. She is the founder of Olyxir Tea Strips and holds two scientific patents rooted in her deep expertise in botanical medicine and regenerative health. She is best known for translating complex research on aging, nutrition, environmental toxins, and functional medicine into practical daily habits, and for her work exposing microplastics and PFAs as one of the most underestimated drivers of accelerated biological aging. Dave Asprey and Josephine cover the full picture: how nanoplastics cross the blood-brain barrier and accumulate in postmortem brain tissue, how endocrine disruption from plastics tanks testosterone and drives fat storage, and why your teabag, canned soup, and yoga pants may be among your biggest sources of daily exposure. They also go deep on real solutions, from lymphatic drainage protocols and infrared sauna to supplements like chlorella, lactobacillus, and olive leaf polyphenols that actively help the body clear microplastics and support longevity and brain optimization. This is essential listening for anyone serious about biohacking, anti-aging, metabolism, brain optimization, supplements, human performance, and smarter not harder approaches to living clean in a toxic world. If you drink tea, cook with plastic utensils, or wear synthetic workout clothes, this episode will change how you make decisions every single day. You'll Learn: Why 0.5 percent of postmortem brain tissue is now made of microplastics and what that means for neuroplasticity and cognitive decline How microplastics mimic estrogen, disrupt metabolism, and make it nearly impossible to lose fat The link between microplastic plaque in carotid arteries and a 4.5x increased risk of cardiac events Which everyday sources, including teabags, canned soup, cookware, and plastic cutting boards, are silently loading your body with nanoplastics How lactobacillus reduced microplastics in the blood by 82 percent in studies, and which other supplements support detox Why Dave Asprey drinks Danger Coffee from a metal container and what his full microplastic reduction protocol looks like How olive leaf polyphenols, with 26,215 micrograms per gram, act as powerful free radical scavengers to support brain optimization and anti-aging The morning lymphatic activation routine that combines rebounding, herbal strips, and whole body vibration for deep cellular detox Why AI and citizen science are accelerating our understanding of microplastic damage faster than traditional medicine Thank you to our sponsors! The One Device | Use code DAVE for $10 off at http://theonedevice.com/daveHeartMath | Go to https://www.heartmath.com/dave to save 15% off.Igniton | Go to Igniton.com and use code DAVE to save 15% off.Puori | Go to http://Puori.com/DAVE or use code DAVE at checkout to get 32% off your Puori Fish Oil subscription. You save more than $18.Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: microplastics, nanoplastics, teabags, detoxification, BPA, endocrine disruptors, brain health, fertility, reproductive health, Josephine Musco, Elixir Tea Strips, sauna detox, infrared sauna, lymphatic system, probiotics, polyphenols, olive leaf, toxins, heavy metals, pesticides, plastic contamination, water bottles, non-stick cookware, synthetic fabrics, inflammation, Alzheimer's, dementia, cognitive decline, testosterone, preconception health, pregnancy, longevity, anti-aging, biohacking, functional medicine, Dave Asprey, environmental toxins, detox protocols, gut health, acacia gum, chlorella, spirulina, whole-body vibration, rebounding Resources: • Get a discount on Olyxir Tea by going to https://www.olyxir.com/ and using code ‘Dave10' at checkout • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Introduction 03:00 – Microplastics in the Brain 08:40 – Olyxir Tea Strip Solution 10:10 – Health Impacts & Weight Gain 11:05 – Environmental Solutions 14:29 – The Teabag Problem 18:57 – How to Remove Microplastics 22:04 – Olive Leaf Benefits 28:26 – Josephine's Scientific Background 33:00 – Guarana & Lymphatic Support 34:22 – Skincare & Microplastics 36:38 – Sauna Protocol 44:19 – Household Exposure Sources 47:18 – Workout Clothing Risk 48:59 – Leather vs Synthetic Fashion 50:54 – Pregnancy & Fertility 54:20 – Closing & Discount Code See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
The new NFL league year is about to start, which means the entire thing will be cut to ribbons and tossed into the air -- the teams as we knew them will cease to exist! It all starts anew for 2026 with a whole bunch of really good skill players about to change teams. On today's podcast we've got a big preview of NFL free agency, with an eye toward how potential player movement will affect fantasy teams this fall! Big fun! Guest: Andy Behrens of TheDeepShot.com. NOTES: Sponsor - www.leesa.com code HARRIS for 20% off and an extra $50 discount on a great mattress Sponsor - www.BetterHelp.com/harris for 10% off your first month of online therapy where you're matched with a psychotherapist who can help Sponsor - www.MoshLife.com/harris to get 20% off protein bars that support brain health and the Women's Alzheimer's Movement Follow Andy Behrens - https://bsky.app/profile/andybehrens.bsky.social Follow our show on Bluesky - https://bsky.app/profile/harrisfootball.com Follow on Twitter - @HarrisFootball Become a Person of the Book - https://www.amazon.com/Christopher-Harris/e/B007V3P4KK Watch the YouTube channel - www.youtube.com/harrisfootball Harris Football Yacht Club Dictionary - https://harrisfootball.github.io/dictionary.html Join the Harris Football Subreddit - www.reddit.com/r/HarrisFootball Subscribe To the Yacht Club Premium Podcast - https://harrisfootball.supportingcast.fm/ Players Discussed Today: Kyler Murray Daniel Jones Malik Willis Tua Tagovailoa Derek Carr Kirk Cousins Mac Jones J.J. McCarthy Kenneth Walker Breece Hall Travis Etienne David Montgomery / Woody Marks Javonte Williams Rico Dowdle Rachaad White Tyler Allgeier J.K. Dobbins Kenneth Gainwell Aaron Jones Alvin Kamara James Conner A.J. Brown George Pickens Alec Pierce Tyreek Hill Stefon Diggs Mike Evans Jauan Jennings Rashid Shaheed Wan'Dale Robinson Romeo Doubs D.J. Moore Michael Pittman Calvin Ridley Brandon Aiyuk Kyle Pitts T.J. Hockenson
For decades, midlife has been framed as a time of decline for women — medically, culturally, and personally. Halle Berry is on a mission to change that. On this episode of The Dr. Hyman Show, she shares how her own menopause journey exposed how little real support exists for the 60 million women navigating this transition. That experience ultimately led her to create ReSpin, the community she couldn't find when she needed it. Watch the full conversation on YouTube or listen wherever you get your podcasts. We discuss: • Why menopause is often missed — and how to take back control of your energy, mood, and metabolism • What changes in your brain, bones, and muscle and how to protect them in midlife • How comprehensive testing gives you a personalized roadmap for this phase of life • Why fatigue, low libido, and brain fog aren't “just aging” — and what improves when you address the root cause Your second act can be your strongest. It's a chance to reclaim your strength, your energy, and your future on your own terms. This conversation was recorded live at the Eudēmonia Summit. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detoxJoin the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Seed, BIOptimizers, PerfectAmino, BON CHARGE, Made In Cookware and Maui Nui. Go to seed.com/hyman and use code 20HYMAN to get 20% off your first month. Head to bioptimizers.com/hyman and use promo code HYMAN at checkout to save 15%. Go to bodyhealth.com and use code HYMAN20 to get 20% off your first order. Upgrade your routine. Head to boncharge.com/hyman and use code HYMAN for 15% off. Head to madeincookware.com and use the code DRHYMAN for 10% off your order. Learn more about the health benefits of venison and how to get yours, head over to mauinuivenison.com/hyman. (0:00) Halle Berry's health journey and the overlooked issue of menopause (1:21) Introduction to the Eudaimonia Summit (3:27) Women's health problems: Causes and personal stories (7:12) Misdiagnosis, confusion, and the mission to educate (10:01) Women's Health Initiative study and FDA updates (12:48) Hormone therapy and perimenopause symptoms (17:22) Lifestyle's role in hormonal health and disease prevention (22:12) Alcohol, nicotine, and long-term health risks like Alzheimer's (25:26) Early hormone replacement therapy and personalized care (28:15) Sexual health discussions and Halle Berry's ReSpin initiative (32:22) Cultural change, low-tox living, and structural health in menopause (37:01) Menopause symptoms variability and addressing health disparities (39:52) The need for medical education reform and JoyLux's contribution (41:12) Psychedelics in mental health treatment (43:43) Closing remarks and listener engagement (44:00) Disclaimer about podcast content