Podcasts about alzheimer's disease

Hey HBs! We're back! And we're back with some stabby energy because what could be better in this moment? We've got a Brynn Weaver spinoff that made all our dreams come true, and made Mel's gardening heart very jealous: TOURIST SEASON. It's book one in her new trilogy The Seasons of Carnage. She's a transplant taking over the mantle of "protecting" her new small town, one wood-chipped tourist at a time. He's a tourist who's determined to turn the tables on her and enact his revenge for the accident that killed his brother and ruined his life. But there's a magnetism neither of them can explain! TW: depictions of caring for an elder loved one with dementia/Alzheimer's. Oh and, like, brutal murder, drowning, dismemberment, and more. Look, man, it's a Brynn Weaver book. Bonus content: Cookie Monster impressions, Mel gets jealous of Harper's compost resources, BIRD watching because she's Harper STARLING, we've upgraded to a Cuck Couch here at HBHQ, and so much more! Want to support the show? Rate and review us on your favorite podcast app! It super helps the algorithm connect us to new listeners.  Want more of us? Check out our PATREON! This week we're talking about the 2nd and 3rd books in Brynn Weaver's Ruinous Love Trilogy LEATHER & LARK and SCYTHE & SPARROW! We're also hosting a Watch Party (virtual live event) on Friday February 20th!  Credits: Theme Music: Brittany Pfantz  Art: Author Kate Prior  Want to tell us a story, ask about advertising, or anything else? Email: heavingbosomspodcast at gmail  Follow our socials:  Instagram @heavingbosoms Tiktok @heaving_bosoms  Facebook group: the Heaving Bosoms Geriatric Friendship Cult The above contains affiliate links, which means that when purchasing through them, the podcast gets a small percentage without costing you a penny more. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

All'interno del programma di RadioPNR, "Buongiorno PNR", il dott. Costantino Girardengo, ospite di Alberto La Piana, ha presentato l'iniziativa promossa dall'Associazione "A Casa con Voi", che Venerdì 20 febbraio, alle ore 21:00, presso i locali della SOMS di Sale, il illustrerà gli obiettivi dell'Associazione che nell' occasione presenterà il libro "Dove sei, sono con te". Racconti di cura, memoria e resistenza nelle demenze". 

In this mini episode, Dr. Derrick Hines breaks down one of the most consistent findings in neurodegenerative research: low glutathione levels in the brain are strongly associated with Alzheimer's and Parkinson's disease.Rather than focusing on genes or medications, this conversation highlights the role of oxidative stress, inflammation, and the brain's heavy oxygen demand and why glutathione, the body's master antioxidant, is so critical for long-term brain health.Dr. Hines explains where glutathione acts in the brain, why levels decline, and how supporting glutathione may play a protective role, especially for those with a family history of neurodegenerative disease.Topics Covered:-- Why glutathione is called the body's master antioxidant-- The brain's high oxygen use and oxidative stress burden-- Glutathione depletion in Alzheimer's and Parkinson's-- The role of glutathione in inflammation and cellular cleanup-- Different ways to support glutathione levels-- Why this matters for long-term brain and nervous system health

Claire hasn't spoken to her father in fifteen years. Now he has Alzheimer's, and she's the only one left to care for him. But the childhood home she returns to has been transformed into a fortress: plywood over windows, deadbolts on every door, cameras watching the yard. Her father speaks of promises kept and men who are gone. He warns her about "the man in the backyard" who watches every night. He begs her not to go in the basement. But behind a steel door with a heavy lock, something waits in the dark. Something connected to a patch of ground where nothing grows. Claire wanted answers. She's about to find out why her father stopped talking fifteen years ago.Unlock an ad-free podcast experience with Caloroga Shark Media! Get all our shows on any player you love, hassle free! For Apple users, hit the banner on your Apple podcasts app. For Spotify or other players, visit caloroga.com/plus. No plug-ins needed!Subscribe now for exclusive shows like 'Palace Intrigue,' and get bonus content from Deep Crown (our exclusive Palace Insider!) Or get 'Daily Comedy News,' and '5 Good News Stories' with no commercials! Plans start at $4.99 per month, or save 20% with a yearly plan at $49.99. Join today and help support the show!We now have Merch!  FREE SHIPPING! Check out all the products like T-shirts, mugs, bags, jackets and more with logos and slogans from your favorite shows! Did we mention there's free shipping? Get 10% off with code NewMerch10 Go to Caloroga.comGet more info from Caloroga Shark Media and if you have any comments, suggestions, or just want to get in touch our email is info@caloroga.com

Send a textWho will take care of me as I age? In this eye‑opening conversation, Dr. Jay Zigmont breaks down the REAL costs and realities of long‑term care — with zero sugar‑coating. Whether you have children or not, Dr. J explains why relying on family isn't a plan, what long‑term care actually costs, and how to prepare before a crisis hits.Learn about his new nationwide solution for solo agers, the Childfree Trust, and why every adult needs a documented plan for who makes decisions when they can't.

A man with Alzheimer's marries his wife of nearly 40 years a second time. The Buddhist monks completed their 2,300-mile “Walk of Peace” and left us with a mindfulness ritual we could all try. This engineer aims to give breast cancer survivors their bodies back. This Nebraskan quit her job to row across the Atlantic by herself and set a race record. Plus, from the ice to the slopes, the incredible Olympic moments from this week.  Sign up for the CNN 5 Good Things newsletter here.  Host/Producer: Krista Bo Polanco  Producer: Eryn Mathewson Showrunner: Faiz Jamil  Senior Producer: Felicia Patinkin  Editorial Support: Victor Blackwell, Kit Maher, Waan Chomchuen  Learn more about your ad choices. Visit podcastchoices.com/adchoices

In his weekly clinical update, Dr. Griffin and Vincent Racaniello are shocked by recent events, including Dr. Oz's appeal for measles vaccination, Vinjay Prasad's unilateral rejection of Moderna's mRNA influenza vaccine application, and the increasing number of New World screw worm cases, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, the number of measles deaths in Mexico, long COVID treatment center, where to go for answers to your long COVID questions, choroid plexus alterations in long COVID association with neuropathologies and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode How Dr. Oz's appeal to get measles vaccine may differ from RFK Jr.'s messaging (ABC News) FDA reverses course, refuses to review Moderna's application for new mRNA flu vaccine (CIDRAP) Hepatitis B Vaccination at Birth: Safety, Effectiveness, and Public Health Benefit (American Academy of Pediatrics: Pediatrics) US Olympic Committee remains 'dialed in' to prevent spread of stomach illness at Winter Games (CNN) Oz promotes measles vaccination (NY Times; USA Today; Fortune) Screw worm in Mexico (Gobierno de Mexico) Mexico reports more human New World screwworm infections (CIDRAP) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard (South Carolina Department of Public Health) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Measles outbreak poses risk of 'irreversible' brain damage, health officials warn (Fox News) In Mexico, at least 28 have died from measles outbreak that started 2025 (Reuters) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) USrespiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: cliff notes (CDC FluView) Influenza vaccination and the risk of myocardial infarction(BMC Publich Health) OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Long-term impact of nirsevimab on prevention of respiratory syncytial virus infection using a real-world global database (Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Where to get pemgarda (Pemgarda) EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulation guidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Choroid plexus alterations in long COVID and their associations with Alzheimer's disease risks (Alzheimer's & Dementia) Reaching out to US house representative Letters read on TWiV 1296 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.

In this episode of the Tick Boot Camp Podcast, Matt Sabatello sits down with Yuri Kim, the lead clinical research nurse for MIT's MAESTRO study, described as one of the largest studies in MIT history focused on Lyme disease and Infection-Associated Chronic Illnesses (IACI). Yuri explains how MAESTRO is collecting deep symptom histories and objective measurements—from eye tracking and EEG/P300 auditory testing to NASA Lean dysautonomia testing, capillaroscopy, and multi-sample biological collection—to identify patterns that validate patient experiences and accelerate real-world clinical understanding. Yuri's story is equally compelling: she began as an ER nurse in a Level 1 trauma center, transitioned into research nursing (including neurodegenerative and traumatic brain injury work), moved to South Korea during the pandemic, and ultimately joined MIT after a conversation with Dr. Mikki Tal changed the course of her career. Throughout the conversation, Yuri shares what she's learned from MAESTRO participants: a community often exhausted and dismissed, yet profoundly motivated to help others and drive scientific progress forward. Key Takeaways (Fast Scan) MAESTRO is nearing ~200 participants enrolled, with the chronic Lyme cohort full and enrollment closing soon. The study aims to objectively measure symptoms often dismissed as “anxiety” or “depression,” especially brain fog and dysautonomia. MAESTRO uses multiple cognitive and neurologic measures, including RightEye eye tracking, EEG + P300 auditory “oddball” testing, and remote cognitive battery tests. The team added capillaroscopy (nailfold and toe microvascular imaging) to explore vascular patterns and hemorrhages in chronic illness cohorts. Dysautonomia testing includes NASA Lean Test plus an earpiece device to estimate proxy cerebral blood flow, sometimes showing abnormalities even when vitals look “normal.” Extensive biological sampling (oral, blood, vaginal/rectal) supports proteomics/immune profiling and deeper molecular analysis. Yuri emphasizes: patients' willingness to participate—despite severe symptoms—is the engine of progress and future change. Detailed Chapter-by-Chapter Show Notes 1) Meet Yuri Kim: The Human Side of Cutting-Edge Lyme Research Matt introduces Yuri as the clinical research nurse leading day-to-day operations of MIT's MAESTRO study—positioning her as a rare bridge between lab science, clinicians, and patients. Yuri shares that the study is approaching enrollment completion and that the team is eager to analyze a large dataset to “speak up” for participants who have suffered without clear explanations. Highlights: MAESTRO is one of MIT's largest studies, with enrollment nearing completion. The mission is to transform patient suffering into measurable signals, data, and insight. 2) Yuri's Background: Pharma, ER Nursing, Research, and Why This Work Became Personal Yuri explains her path: early work as a medical information specialist in pharma (including literature searches and clinician guidance, often involving off-label questions), then an intense period as a Level 1 ER nurse where she witnessed both acute crises and chronic illness desperation. Key insight:Yuri notes that in pharma and ER settings, she repeatedly saw the same reality—patients searching for answers, clinicians constrained by time, and chronic illness voices falling through the cracks. 3) From the ER to Neuro Research: Brain Inflammation, TBI, and the Gap in Chronic Illness Care Yuri left ER work largely due to the physical toll of night shifts and moved into academic research at Boston University. She worked on complex studies involving Alzheimer's, amyloidosis, and traumatic brain injury. Matt asks whether Lyme came up in those neuro settings. Yuri says no—but now she views neurodegenerative symptoms differently and believes clinicians should consider underlying root causes, including infection. Listener connection:This segment reinforces how often Lyme-related cognitive decline can be misinterpreted or missed when viewed through siloed specialties. 4) Lyme Awareness Outside the U.S.: South Korea, Tick-Borne Illness, and Global Blind Spots During the pandemic, Yuri relocated to South Korea. She shares that Lyme isn't commonly discussed there, though other tick-borne illnesses exist. Yuri underscores a global concern: agricultural and rural communities face tick exposure without awareness of the chronic implications. 5) How Yuri Joined Dr. Mikki Tal and MAESTRO (And Why She Changed Her Mind) One of the most memorable segments: Yuri reveals she had already accepted another MIT nursing role—but after speaking with Dr. Tal, she pivoted immediately, calling it the best career decision she's ever made. Why it matters: It shows how MAESTRO is not just a study; it's a mission-driven effort that attracts top clinical talent. 6) Day One at MAESTRO: Meeting the Severely Ill and the Community's Unmatched Generosity Yuri recounts a powerful early experience: meeting a participant who was bedbound and profoundly symptomatic, yet eager to contribute anything possible to help the community. Matt connects this to Tick Boot Camp's origin story: people with minimal energy still showed up to help others. The theme becomes clear—Lyme patients are often depleted but relentlessly generous. What MAESTRO Measures (The Four-Hour Visit Breakdown) 7) Brain Fog: Why MAESTRO Treats It as a Complex Phenomenon Yuri explains MAESTRO's approach: brain fog isn't one symptom. It can involve memory, processing speed, visual stimulation sensitivity, pain-triggered cognition changes, and motor response delays. Core idea: MAESTRO attempts to measure brain fog from multiple angles—visual processing, auditory processing, reaction time, and executive function. 8) RightEye Eye Tracking: Visual Stimulus + Reaction Time as Objective Signal Participants complete a structured set of ocular motor tasks (pursuit, saccades) and reaction-time games (shape recognition mapped to numbered inputs). Yuri notes many chronic illness participants struggle even with basic saccades, often aligning with reported visual disturbances. What MAESTRO is measuring: Ocular motor control Visual processing Decision speed Reaction time consistency 9) EEG + P300 “Oddball” Test: Auditory Processing Meets Motor Output Participants wear an EEG cap (19 regions) and listen to tones: common low-pitch and rare high-pitch. They must press the spacebar only for the rare tone. Yuri notes that even a 4-minute test can be exhausting for people with cognitive dysfunction, and participants often describe a frustrating “delay” between knowing what to do and physically doing it. Why this matters: This may help validate cognitive dysfunction even when standard office screening looks normal. 10) Remote Cognitive Battery Testing: Scaling Measurement Beyond MIT Participants complete executive function tests at home (memory, Stroop-like color-word matching, trail-making tasks). Yuri emphasizes why this matters: many patients can't travel, and symptoms vary dramatically by day, cycle, and crash patterns. Big future direction: Remote testing could expand access to bedbound patients and capture “good day vs bad day” variability. 11) Dysautonomia & POTS: NASA Lean Test + Proxy Cerebral Blood Flow Yuri details NASA Lean testing: supine rest, then standing/leaning while monitoring vitals and symptoms. The standout: sometimes vitals appear stable while patients feel intensely symptomatic—yet the cerebral blood flow proxy measurement fluctuates significantly. Clinical implication discussed: This approach could become a tool for identifying dysautonomia-related issues when standard vitals “look fine.” 12) Capillaroscopy: Nailfold + Toe Microvascular Imaging MAESTRO added capillaroscopy to examine microvascular patterns, including abnormal shapes and possible hemorrhages seen more frequently in chronic cohorts (as her clinical observations suggest). They also measure capillaries pre- and post-NASA Lean to explore whether symptomatic shifts correlate with microvascular changes. Why patients find it meaningful: They can visually see something measurable that aligns with how they feel. 13) Standard Neuro Screening Doesn't Capture Lyme Brain Fog Yuri shares a crucial point: participants often perform fine on standard screens like the Mini-Mental State Exam, suggesting that infection-associated cognitive dysfunction can be subtle, dynamic, and not detected by traditional tools—reinforcing the need for MAESTRO-style measurement. Biological Samples: “Measure Everything” (Head to Toe) 14) Multi-Sample Collection: Oral, Blood, Vaginal, Rectal Yuri explains the breadth of biological sampling, including saliva/oral samples (cotton chew + gum swab), multiple blood tubes, and sex-specific sampling to explore immune, hormonal, microbiome, and gynecologic dimensions. Why it's being done: To connect symptom clusters to molecular patterns and explore sex differences in chronic illness response. 15) Storage, Batch Effects, and What Happens After Enrollment Closes Samples are aliquoted and stored at -80°C until they can be processed/shipped in ways that minimize batch effects. The next phase is analysis and collaboration—including proteomics and immune signaling exploration. 16) Giving Back to Participants: The Challenge and the Intention Yuri acknowledges the “fine line” between research-only testing and clinically actionable reporting, but stresses MIT's intention to return what can be responsibly shared through certified partners—while being careful not to over-interpret research findings. Collaboration, Scaling, and What Comes Next 17) Collaboration Across Institutions: The Missing Platform Matt compares Lyme research needs to cybersecurity threat-sharing between banks: competitors collaborate because the threat is bigger than any one organization. Yuri agrees and highlights the need for secure data-sharing platforms—similar to large national efforts in other fields. 18) What's Next: Focus on Female Brain Fog, Hormones, and Remote Studies Yuri previews upcoming directions: Brain fog and hormone cycle relationships Differentiating infection-associated cognitive dysfunction vs menopause-related brain fog Remote/at-home measurement studies to reach more symptomatic and bedbound patients Potential collaborations with pediatric and neuroimmune experts Closing Message: Hope Without Hype Yuri's message to patients and families is simple and emotional: “Please don't give up.” She believes answers are coming because serious teams are working together—and because patients are driving the research forward with their participation.

A man with Alzheimer's marries his wife of nearly 40 years a second time. The Buddhist monks completed their 2,300-mile “Walk of Peace” and left us with a mindfulness ritual we could all try. This engineer aims to give breast cancer survivors their bodies back. This Nebraskan quit her job to row across the Atlantic by herself and set a race record. Plus, from the ice to the slopes, the incredible Olympic moments from this week.  Sign up for the CNN 5 Good Things newsletter here.  Host/Producer: Krista Bo Polanco  Producer: Eryn Mathewson  Showrunner: Faiz Jamil  Senior Producer: Felicia Patinkin  Editorial Support: Victor Blackwell, Kit Maher, Waan Chomchuen Learn more about your ad choices. Visit podcastchoices.com/adchoices

LEITURA BÍBLICA DO DIA: 1 CORÍNTIOS 13 PLANO DE LEITURA ANUAL:  LEVÍTICO 15–16; MATEUS 27:1-26  Já fez seu devocional hoje? Aproveite e marque um amigo para fazer junto com você! Confira:  João e Laís namoraram durante a faculdade, casaram-se e viveram felizes por muitos anos. Mas Laís começou a agir de forma estranha, perdendo-se e esquecendo seus compromissos. Ela foi diagnosticada com a doença de Alzheimer aos 47 anos. Após uma década servindo-a como seu cuidador principal, João disse: “A doença deu-me a oportunidade de amar e servir minha esposa de maneiras inimagináveis quando disse o ‘Sim'”. Ao explicar os dons do Espírito Santo, Paulo escreveu extensivamente sobre a virtude do amor (1 CORÍNTIOS 13). Comparou os ser viços rotineiros com virtudes que transbordam de um coração amoroso. Ensinou que falar com autoridade é bom, mas sem amor é como barulho sem sentido (v.1). “Se […] entregasse meu corpo para ser queimado, e não tivesse amor, de nada me adiantaria” (v.3) e acrescentou: “permanecerão: a fé, a esperança e o amor, e a maior delas é o amor” (v.13). João compreendeu melhor sobre amar e servir à medida que cuidava de sua esposa. Apenas um amor profundo e duradouro poderia dar-lhe forças para apoiá-la todos os dias. Em última aná lise, o único modelo perfeito desse amor sacrificial é o amor de Deus por nós, que o fez enviar Jesus para morrer por nossos pecados (JOÃO 3:16). Esse ato de sacrifício, motivado pelo amor, transformou nosso mundo para sempre.  Por: KAREN PIMPO 

A hidden DUI. Secret drinking. Constant lies. You escaped an alcoholic mom only to marry the same pattern. Is it time to break free? It's Feedback Friday!And in case you didn't already know it, Jordan Harbinger (@JordanHarbinger) and Gabriel Mizrahi (@GabeMizrahi) banter and take your comments and questions for Feedback Friday right here every week! If you want us to answer your question, register your feedback, or tell your story on one of our upcoming weekly Feedback Friday episodes, drop us a line at friday@jordanharbinger.com. Now let's dive in!Full show notes and resources can be found here: jordanharbinger.com/1284On This Week's Feedback Friday:Whatever happened to Captain Save-a-Ho from episode 1240? We have an update!Your husband hid a DUI from you for seven months — and that's just the latest in a long pattern of secret drinking, edibles, and lies. Given your childhood with an alcoholic mom, you're now facing an impossible question: How many more chances do you give him before you walk away for good?Your recently widowed 65-year-old dad is falling for obvious romance scams, posting thirsty comments on "hot MILFs" pics on his own Facebook, and claiming he was hacked. You've tried warning him, but he doesn't care — he just wants companionship now. Can you save him from himself? [Thanks to crime investigator Javier Leiva for helping us sort this one out!]Your employer pulled a bait-and-switch, stripping your $50k IVF coverage and offering a measly $15k consolation while HR ghosted you for months. You were mid-cycle, your medical window closed, and you snapped. Now you're wondering: Do you have a legal case against them? [Thanks to HR professional Joanna Tate for helping us with this one!]Recommendation of the Week: The Rolling Square AirCard — a credit card-sized Bluetooth tracker that works with Apple and Android, fits in your wallet or luggage tag, charges wirelessly, and lasts a year. It even has a QR code so finders can contact you directly.Jordan shares a personal update: His mom was recently diagnosed with Alzheimer's. He reflects on catching the signs, navigating the healthcare process, and learning to cherish the time they have left — a vulnerable reminder to appreciate your parents while you can.Have any questions, comments, or stories you'd like to share with us? Drop us a line at friday@jordanharbinger.com!Connect with Jordan on Twitter at @JordanHarbinger and Instagram at @jordanharbinger.Connect with Gabriel on Twitter at @GabeMizrahi and Instagram @gabrielmizrahi.And if you're still game to support us, please leave a review here — even one sentence helps! Sign up for Six-Minute Networking — our free networking and relationship development mini course — at jordanharbinger.com/course!Subscribe to our once-a-week Wee Bit Wiser newsletter today and start filling your Wednesdays with wisdom!Do you even Reddit, bro? Join us at r/JordanHarbinger!This Episode Is Brought To You By Our Fine Sponsors: The Cybersecurity Tapes: Listen here: thecybersecuritytapes.comQuince: Free shipping & 365-day returns: quince.com/jordanSimpliSafe: 50% off + 1st month free: simplisafe.com/jordanHomes.com: Find your home: homes.comAG1: Welcome kit: drinkag1.com/jordanSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

#689: Most people think forgetting a name means their brain is failing.  Dr. Majid Fotuhi, a neurologist who taught at Johns Hopkins and Harvard, sees thousands of patients convinced they have Alzheimer's – only to discover they're dealing with poor sleep or stress. Dr. Fotuhi joins us to break down the difference between cognitive decline, dementia and Alzheimer's disease. He explains why chronic stress physically shrinks your hippocampus — the thumb-sized memory center in your brain — and how twelve weeks of lifestyle changes reversed cognitive decline in 84 percent of his patients. We talk about the five hidden taxes draining your brain: sedentary lifestyle, poor sleep, junk food, chronic stress and mental laziness. Scrolling social media after work counts as mental laziness, even if your day job involves intense focus. Dr. Fotuhi offers a different framework: five pillars that compound over time. Exercise ranks first because it multiplies mitochondria in your brain cells, reduces inflammation and generates new neurons in your hippocampus. Walking 10,000 steps daily cuts Alzheimer's risk by 50 percent. Sleep comes second. Your brain rinses itself during deep sleep, flushing out amyloid — the core protein in Alzheimer's disease. One night of poor sleep increases amyloid in your brain. We cover nutrition (skip the junk food debate), mindset (heart rate variability breathing reduces Alzheimer's footprints) and brain training. Dr. Fotuhi memorizes 70 names in a single lecture and explains his technique for remembering credit card numbers using mental imagery. The conversation covers London taxi drivers who grew their hippocampus by memorizing 10,000 streets, why stress management beats supplements, and how Swedish students learning Arabic increased their brain volume in three months. Timestamps: Note: Timestamps will vary on individual listening devices based on dynamic advertising segments. The provided timestamps are approximate and may be several minutes off due to changing ad lengths. (00:00) Defining cognitive decline, dementia and Alzheimer's disease (05:19) Why cognitive issues don't always mean Alzheimer's (07:24) Thinking of your brain as an asset to manage (07:51) The five hidden taxes draining your brain (10:45) How poor sleep prevents brain rinsing and causes inflammation (14:20) Oral health and brain health connection (16:40) Brain plasticity and the Broca lobe (27:02) The five pillars of brain health (35:23) Cardiovascular fitness versus strength training for brain health (38:51) Sleep as the second pillar of brain health (48:05) When exercise beats sleep (51:33) Different types of intelligence beyond IQ tests (1:03:53) Reversing brain damage from decades of bad habits (1:10:25) Nutrition and avoiding junk food (1:25:09) Mindset and stress management as pillar four (1:33:35) Breathing exercises for stress reduction (1:39:24) Brain training as the fifth pillar (1:51:52) Memory techniques for names and numbers (2:02:46) Nootropics and supplements for brain health Learn more about your ad choices. Visit podcastchoices.com/adchoices

Did you know that 100 million people in the US have prediabetes? Prediabetes is one of the biggest health challenges that our country faces. It increases the risk of diabetes, but also increases the risk of heart disease, cancer, Alzheimer's, and more. The good news is that most of these cases are reversible with nutrition and lifestyle changes. On today's podcast, we are going to discuss what those nutrition and lifestyle changes are. In this episode, we cover:What prediabetes isHealth risks associated with prediabetesHow to test for prediabetesHow prediabetes developsNutrition and lifestyle strategies  for reversing it Tune into the episode to learn more. If you are interested in applying for the Metabolism Mastery Bootcamp, you can find more info here. Enjoying the show or have a questions about a particular topic? Send us a message here. Support the showDo you enjoy the show and want to support it? Here are some ways you can

In honor of National Alzheimer and Dementia Care Educators Week (Feb 14–21), Teepa Snow and Greg Phelps take on a specific headline that reads: You can be a dementia therapy practitioner by next week. They unpack why quick certification promises can miss what matters most—building real, person-centered skills that help you respond to brain change in the moment, with confidence and respect.Ready to move beyond quick-fix dementia training? Join the Positive Approach to Care® Dementia Trainer Certification (live online) to build practical, person-centered skills you can use—and teach. Next live online dates: Feb 17–18, 2026This podcast is distributed on third-party platforms (including Spotify and Apple Podcasts) to make listening more accessible and convenient for our community. Our presence on any platform does not indicate endorsement of that platform, its owners, its policies, moderation decisions, advertising practices, or any other content hosted or shared there. The views and opinions expressed in this episode are those of the speakers and do not necessarily reflect the views of Positive Approach to Care® (PAC™).

Dr. Greg Cooper and Dr. David G. Coughlin discuss the role of αSyn-SAAs in diagnosing DBL and their relationship with Alzheimer's disease biomarkers.  Show citation: Coughlin DG, Jain L, Khrestian M, et al. CSF α-Synuclein Seed Amplification Assays and Alzheimer Disease Biomarkers in Dementia With Lewy Bodies: Presentation and Progression. Neurology. 2025;105(12):e214346. doi:10.1212/WNL.0000000000214346 Show transcript:  Dr. Greg Cooper: Hi, this is Dr. Greg Cooper. I just finished interviewing Dr. David Coughlin for this week's Neurology Podcast. For today's Neurology Minute, I'm hoping you can tell us the main points of your paper. Dr. David Coughlin: The main points of this paper in my mind is that α-Synuclein seed amplification assays from cerebrospinal fluid samples is useful in confirming the presence of synuclein pathology in people with clinically suspected dementia with Lewy bodies. But also that, for people who have synuclein positivity, that the presence of Alzheimer's disease mixed pathology is associated with a worse cognitive progression over time. Dr. Greg Cooper: Thank you Dr. Coughlin, for that summary and for all of your work on this topic. Please check out this week's podcast to hear the full interview and read the full article published in Neurology, CSF α-Synuclein Seed Amplification Assays and Alzheimer's Disease Biomarkers in Dementia with Lewy Bodies. Thank you.

Creatine isn't just for bodybuilders anymore. In this episode, we break down what creatine actually does in the body — and why researchers are now studying it for brain health, muscle preservation, and healthy aging. You'll hear about typical dosing (3–5 grams daily), what we know about safety, and what the latest research shows in older adults — including a small pilot study in Alzheimer's patients using higher doses that increased brain creatine levels by about 10%. But does that mean everyone should take it? Not so fast. We'll walk through who might benefit, who should be cautious, and how to think about supplementation through a lifestyle medicine lens. If you're navigating midlife changes, muscle loss, brain fog, or just trying to age with strength and clarity, this episode will help you make an informed decision. Because supplements should support a healthy foundation — not replace one. Resources: Keep Your Brain Sharp Get every episode in your inbox Browse more episodes

A new AI cafe in NY lets you go on dates in public with fake people, another Guthrie update, the Daytona 500 is this weekend, Valentine's Day is tomorrow, why we don't have the cure for Alzheimer's, and robots with warm skin...

In this IMMH 2023 conference presentation on "Sex Hormones and their Impact on Mental Health", Dr. Gersh explains why ovarian hormones influence so much more than reproduction – and why they are a missing ingredient in many conversations about brain health, mood disorders and cognitive decline. She highlights the disproportionate burden of depression and anxiety in women and notes that nearly a quarter of women in their 40s and 50s (peri/early menopause) are being prescribed antidepressants, arguing that hormone health must be considered as part of the bigger clinical picture. Dr. Gersh is a dual board-certified OB-GYN and integrative physician, founder and director of the Integrative Medical Group of Irvine, and a leading voice in women's hormonal and metabolic health. In this session she combines clinical and scientific data and decades of experience to demonstrate that estradiol (E2) plays a central, protective role in the brain, supporting energy production, regulating inflammation and maintaining neurological resilience. In this very informative and practical talk, Dr. Gersh outlines how hormonal decline and disruption can increase vulnerability to mood disorders, migraines, cognitive symptoms and neurodegeneration – and how optimizing hormones through lifestyle, nutrition and psychological therapies can help protect long-term brain health. The overall message is both preventative and hopeful: many hormone-related mental health risks are modifiable and treatable. In this episode, you will learn: Why sex hormones function as whole-body "life/health hormones," supporting brain, metabolic and immune health – not just reproduction. How hormones are a missing piece in many discussions of depression, anxiety and cognitive decline in women. That almost 25% of peri- and early-menopausal women are prescribed antidepressants, highlighting the scale of midlife mood symptoms. The association between teen oral contraceptive use and higher lifetime cardiovascular events, including heart attacks and strokes. How estradiol (E2) is strongly neuroprotective, supporting brain energy metabolism and cellular resilience. Why women have approximately 2.5× the incidence of Alzheimer's disease, and how hormone loss may contribute to that risk. How estradiol helps regulate microglia, astrocytes and neuroinflammation, keeping the brain's immune response balanced. The role of estradiol in maintaining the blood–brain barrier, and how deficiency may increase inflammatory vulnerability. Emerging evidence that low-dose estradiol therapy may support mood stability, including in postpartum depression and certain bipolar presentations. Why progesterone is also neuroprotective and anti-inflammatory, with important roles in mood, mitochondrial function and overall brain health.

FULL podcast here: https://youtu.be/tNoDNnpSkdADo you feel like two different people across your cycle? Understanding the brain effects of estrogen and progesterone can help you trust both advisors within you. This clip explores the often overlooked luteal phase, why progesterone matters for mood, sleep, and decision making, and how it's used after concussion to protect the brain. We also touch on perimenopause care and why progesterone isn't just for the uterus, plus emerging questions about neuroprotection and Alzheimer's. Watch the ***This episode is sponsored by:NOWATCH: The compassionate health trackerConnecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at https://nowatch.com/Mojo: the app for expert-led courses in better sex.Learn from world-class sex therapists and relationship experts with courses tailored to your needs.15% off with code LiveWell15 at mymojo.com/livewellbewell***The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.

Local media declares the BNP winner of Bangladesh's first election since the ousting of Hasina, the U.S. House votes to disapprove of Trump's Canada tariffs, Kim Jong Un's daughter is reportedly named his successor-designate, the White House announces the end of ICE's Operation Metro Surge in Minnesota, Switzerland schedules a vote on capping the population at 10 million, the U.S. House passes a Trump-backed bill to create new voting rules, a principal dies after being shot during a school siege in Thailand, a Ukrainian athlete is disqualified from the Winter Olympics for refusing not to wear a helmet deemed to violate rules on political expression, a study links reading and writing to a 38% decreased risk of Alzheimer's, and Gallup ends its 90-year tradition of publishing presidential polls. Sources: Verity.News

In today's podcast, my guest is Dr Bill Wilson, a front-line physician who practiced medicine in Minnesota and Massachusetts for over 40 years. Three years ago, Dr Wilson was diagnosed with mild cognitive impairment - often described as pre-dementia. Instead of accepting it as inevitable, he took action. The result? He reversed it. Now, drawing on both his medical background and personal experience, Dr. Wilson has developed a sharp, highly practical focus on neuroscience. In this conversation, he breaks down exactly what helped restore his cognitive function - and, just as importantly, what truly matters for anyone on the slippery slope of cognitive decline. If brain health is something you—or someone you love—are thinking about, this episode is essential listening.   For more information read my book 'Upgrade Your Brain' and visit the Alzheimer's and Dementia Topic on my website.  Take the Food for the Brain Cognitive Function Test.   

Your fluoride toothpaste and antiseptic mouthwash may be sabotaging your cardiovascular health and canceling out the benefits of your daily workout. In today's episode, I sit down with Dr. Nathan Bryan to uncover how nitric oxide deficiency drives high blood pressure, erectile dysfunction, insulin resistance, and even Alzheimer's disease. Nathan explains why 50% of men on Viagra don't respond with better erections, how mouthwash kills the bacteria your body needs to produce nitric oxide, and why heavy metals scavenge this critical molecule before it can reach your blood vessels.  We explore practical solutions such as using nitric oxide lozenges, reducing exposure to harmful substances, and supporting the oral microbiome to restore your body's natural production.   "Without nitric oxide, your body cannot heal. It's not going to get adequate blood flow, you're going to experience runaway inflammation, oxidative stress, and immune dysfunction." ~ Nathan Bryan   In This Episode: - Nitric oxide and its importance for our health - Nitric oxide and erectile dysfunction - Exercise and bacteria for nitric oxide production - Oral microbiome and dangers in your mouthwash - Signs and consequences of low nitric oxide - Age-related decline in nitric oxide production - Heavy metals and toxins that scavenge nitric oxide - How to restore nitric oxide - Nitric oxide lozenges and skin care solutions - The beet product myth debunked - High blood pressure medication limitations - Who needs nitric oxide supplementation?   Products & Resources Mentioned: N1O1 Nitric Oxide Lozenges: Available at https://n101.com  N1O1 Nitric Oxide Skincare Serum: Perfect for youthful skin maintenance at https://n101.com  Puori Grass Fed Whey Protein: Use code WENDY at http://Puori.com/wendy for 32% off, plus a free shaker with a subscription. Tru Energy Skincare Serum: Get an exclusive deal at https://trytruenergy.com/wendy  Organifi Collagen: Save 20% with code MYERSDETOX at https://organifi.com/myersdetox  Chef's Foundry P600 Ceramic Cookware:  Take 50% off plus an extra 20% with code WENDY20 at https://chefsfoundry.com  Heavy Metals Quiz: Visit https://heavymetalsquiz.com    About Nathan Bryan: Dr. Nathan Bryan earned his Bachelor of Science in biochemistry from UT Austin and his doctoral degree from Louisiana State University School of Medicine in Shreveport, where he received the Dean's Award for Excellence in Research. He completed postdoctoral training as a Kirschstein Fellow at Boston University School of Medicine and at the Whitaker Cardiovascular Institute before joining the faculty at UT Health Science Center at Houston, recruited by Nobel Laureate Ferid Murad. Nathan is also the author of The Secret of Nitric Oxide, available on his website. With over 25 years of nitric oxide research, he has made seminal discoveries, founded Bryan Therapeutics for nitric oxide-based drugs in heart disease, Alzheimer's, and wound healing, and created the successful consumer nitric oxide product line available at https://n101.com    Disclaimer The Myers Detox Podcast was created and hosted by Dr. Wendy Myers. This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast, including Wendy Myers and the producers, disclaims responsibility for any possible adverse effects from using the information contained herein. The opinions of guests are their own, and this podcast does not endorse or accept responsibility for statements made by guests. This podcast does not make any representations or warranties about guests' qualifications or credibility. Individuals on this podcast may have a direct or indirect financial interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.

In this episode of the Farm4Profit Podcast, we sit down with Tom Corcoran, better known online as Farming Sumbitch, a first-generation farmer from rural western New York who has built something truly special — both online and in real life.Tom shares the story behind the SUMBITCH Tractor Show (Some Unique Machines Brought In To Commemorate History), an annual August event hosted on his family's farm that now draws visitors from across the U.S. — and even internationally. What began in 2018 as a small idea has grown into a show featuring 150+ tractors, tractor rides, hay rides, live music, food, and a mission much bigger than machinery.The show raises money to support the fight against Alzheimer's disease, a cause close to Tom's heart after his father-in-law battled the disease. In 2024 alone, the event raised over $40,000, proving that agriculture still has the power to bring people together for something bigger than itself.We also dive into:Tom's journey as a first-generation farmer, starting independently in 2010What it's really like farming corn, wheat, rye, black beans, and pumpkins in New YorkWhy old iron still matters — including shelling corn with a 3-row picker and running classic John Deere equipmentThe growth of his “The Way We Farm” YouTube channel and why showing real farming still resonatesHow social media helped connect a small farm to a global audienceWhy preserving ag history matters just as much as adopting new technologyThis episode is about more than tractors. It's about honoring where agriculture came from, sharing real farm life, and using your platform — no matter how small it starts — to make a real impact. Want Farm4Profit Merch? Custom order your favorite items today!https://farmfocused.com/farm-4profit/ Don't forget to like the podcast on all platforms and leave a review where ever you listen! Website: www.Farm4Profit.comShareable episode link: https://intro-to-farm4profit.simplecast.comEmail address: Farm4profitllc@gmail.comCall/Text: 515.207.9640Subscribe to YouTube: https://www.youtube.com/channel/UCSR8c1BrCjNDDI_Acku5XqwFollow us on TikTok: https://www.tiktok.com/@farm4profitllc Connect with us on Facebook: https://www.facebook.com/Farm4ProfitLLC/ Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Dr Eric Topol is a relentless pioneer, a visionary cardiologist, and a groundbreaking scientist who is not merely observing the future of health but actively building it. With a keen focus on leveraging cutting-edge technology and evidence-based science, he challenges the status quo in medicine, pushing for a radical shift from treatment to prevention. His work is reshaping our understanding of longevity, healthspan, and the profound impact of AI, offering a blueprint for a healthier, more informed tomorrow.Takeaways:The "Because" of Prevention: Dr. Topol's deep-seated motivation stems from witnessing preventable suffering and death within his own family, fueling his drive to transform medicine from a reactive treatment model to a proactive prevention paradigm.Demystifying Superagers: Contrary to common belief, the extraordinary health and longevity of "superagers" are primarily attributed to lifestyle choices and robust immune systems, not solely genetics, offering an empowering message that healthy aging is largely within our control.AI's Triple Threat in Healthcare: Artificial intelligence is poised to revolutionize healthcare by enhancing diagnostic accuracy, returning valuable time to clinicians by streamlining administrative tasks, and most profoundly, by enabling personalized disease prevention strategies.Sound Bytes:"I just think we can do so much better to prevent the major diseases, not just there that I've been in for my career, cardiovascular, but also neurodegenerative, preventing Alzheimer's and also preventing cancer.""We now are empowered to go that route. And it's a lot like what I experienced in the early 80s, which is when a field within medicine went through a radical change. We need to do that more frequently than every decade or two.""I figured, well, I'm condemned to the same fate. So I've always been interested in genetics and health span, lifespan. And we did a study we called the Welderly. And the Welderly, basically another name for them, are superagers."Connect & Discover Dr Eric:Instagram: @erictopol1X: @EricTopolSubstack: @Ground TruthsBook: Super Agers: An Evidence-Based Approach to LongevityLinkedIn: @eric-topolYouTube: @EricTopolSRTI

Dr. Greg Cooper talks with Dr. David G. Coughlin about the role of αSyn-SAAs in diagnosing dementia with Lewy bodies and their relationship with Alzheimer disease biomarkers.  Read the related article in Neurology®.  Disclosures can be found at Neurology.org. 

Is there a built-in "fat switch" in our genes—something nature designed to help us store fat for survival? And if so, what does that mean for food addicts living in a world saturated with ultra-processed food? In this episode, Dr. Vera Tarman sits down with Dr. Richard Johnson, Professor Emeritus at the University of Colorado, former Chief of the Division of Renal Diseases and Hypertension, author of The Sugar Fix, The Fat Switch, and Nature Wants Us to Be Fat, and a researcher with 700+ scientific papers to his name. Dr. Johnson explains how fructose (from sugar and high-fructose corn syrup—but also produced inside the body under certain conditions) can activate a powerful metabolic pathway that increases hunger, lowers cellular energy, and shifts calories toward fat storage. He connects this to uric acid, salt, high-glycemic carbohydrates, and the modern "perfect storm" of ultra-processed foods engineered to intensify cravings. Together, they explore the evolutionary logic of fat storage, why visceral fat may have had survival value, why "calories in/calories out" fails to explain the whole picture, and what practical steps can help people restore metabolic flexibility—including carbohydrate reduction, movement that supports mitochondrial health, and the emerging role of GLP-1 medications as a tool (not a replacement) for nutrition change. What You'll Learn

It has been an absolutely Awful Week for everyone who has been paying attention to the latest release of the Epstein files, both on this continent and around the world. We're taking a look at what the documents reveal about Europe's rich and powerful and whether any overdue reckonings might come out of the horrific revelations. On the brighter side: we also discuss a sitting president who does NOT want to be handed the Nobel Peace Prize. A win for us all!   Our guest this week is journalist Salsabil Fayed, co-author of the recent Follow the Money investigation “U.S. donors bankroll Europe's policy ideas through think tanks”. (Gulp.) What does it mean that some of the biggest American tech companies are financing some of the work of some of the most influential think tanks on this side of the Atlantic? Salsabil spells it all out.   This week's Inspiration Station recommendations are Fairphone and not looking at your phone in the morning. So…go out and touch grass. (But catch up on your podcasts first.)   Resources for this episode:   “Moldovan president rejects Nobel Peace Prize nomination, says Ukrainian POWs deserve it instead” – Yahoo! News, 6 February 2026 “Holding the Line Between Democracy and Putin | President of Moldova, Maia Sandu” – The Rest is Politics, 11 January 2026 “Los ‘miles de fallos' que exponen a las víctimas de los papeles de Epstein” – El Pais, 4 February 2026 “A survivor on the Epstein files – podcast” – The Guardian, 5 February 2026  Soundos el Ahmadi sets the record straight about misogynist violence on Flemish TV – De Afspraak, 7 February 2026 “U.S. donors bankroll Europe's policy ideas through think tanks” – Follow the Money, 23 October 2025 “Podcast | The hidden U.S. influence on Europe's policymaking” – Follow the Money, 10 December 2025 “US pressure revives call for powerful EU tech regulator” – Politico Europe, 18 January 2026  Screen time increases risk of dementia – Brankele Frank on Brainwash, January 2026 (In Dutch) “Digital dementia in the internet generation: excessive screen time during brain development will increase the risk of Alzheimer's disease and related dementias in adulthood” – Journal of Integrative Neuroscience, 28 January 2022    Are you a visual learner rather than an auditory one? We got you. Here's our new newsletter. (Almost) all of what you like from the weekly podcast, but…quieter. It's nice. Try it.   This podcast was brought to you in cooperation with Euranet Plus, the leading radio network for EU news. But it's contributions from listeners that truly make it all possible—we could not continue to make the show without you! If you like what we do, you can chip in to help us cover our production costs at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠patreon.com/europeanspodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ (in many different currencies), or you can gift a donation to a superfan. We'd also love it if you could tell two friends about this podcast. We think two feels like a reasonable number. Produced by Morgan Childs and Wojciech Oleksiak Editorial support from Katy Lee Mixing and mastering by Wojciech Oleksiak Music by Jim Barne and Mariska Martina YouTube | Bluesky | Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ | Mastodon⁠⁠⁠⁠⁠⁠⁠⁠⁠ | Substack | hello@europeanspodcast.com

Could nature-based principles outperform modern productivity hacks? This episode, Dr. Aldrich Chan connects neuroscience, Daoist wisdom, & bioharmonized living to help high achievers move out of survival mode & into a more grounded, adaptive, & high-performing state. Meet our guest Dr. Chan is a neuropsychologist, psychotherapist & award-winning author of Reassembling Models of Reality & 7 Principles of Nature: How We Strayed & How We Return. He is the founder of the Center for Neuropsychology & Consciousness in Miami, with a background in research on Alzheimer's disease, trauma & the Default Mode Network, plus experience teaching at Pepperdine University. His work integrates neuroscience, psychotherapy, mindfulness, creativity & long-standing study of Daoism & Zen. Thank you to our partners Outliyr Biohacker's Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Modern suffering stems from separation, alienation, & discord (SAD) as brain networks drive disconnection in today's world Living by CPR West—Creativity, Process, Relationship, Wholeness, Equilibrium, Spontaneity, & Transformation—provides a blueprint for optimal living Creativity reflects change & adaptation, not artistic talent, with every mind wired for continual reinvention Prioritizing process over perfection invites presence by engaging with life's constant flow instead of rigid routines or identities Challenges like ADHD reflect evolutionary mismatch or misalignment with natural principles rather than simple disorders to suppress Intuition functions as rapid unconscious processing that guides strong decisions in complex or uncertain situations Human connection synchronizes biology & brain function with people & nature, supporting mental & physical health Growth emerges from accepting all parts of the self, including unwanted traits, & channeling them productively Regulating aspirational, selfish, & survival desires reduces overwhelm by simplifying choices Playfulness, flexibility, & continual adaptation drive true performance, with transformation remaining an ongoing process Episode highlights 01:17 Identify why modern life creates suffering 05:39 Use nature-based principles to restore function 09:57 Apply creativity & process for adaptive performance 36:14 Strengthen relationship & wholeness 54:27 Maintain equilibrium without rigidity 01:01:06 Activate spontaneity & transformation Links Watch it on YouTube: https://youtu.be/-HLS8qYAY_M Full episode show notes: outliyr.com/248 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

Patreon sample: This week in our history deep dive we are examining the life of Dr Solomon Carter Fuller, credited as the first Black Psychiatrist in the USA. Born of formerly enslaved parents, Dr Fuller grew up to become a psychiatrist, neurologist, and professor at Boston College. His groundbreaking research in the discovery of Alzheimer's disease is still the foundation of much research and treatment today.  Go to www.thelavenderproject.org to support this month's highlighted nonprofit, providing legal and practical assistance for Black Trans Americans. 50% of donations from Patreon members who join this month will go to The Lavender Project as long as they remain donors. That's why they get 50% more episode today than the general public. 

Here's a question for you that may at first seem trivial, but is actually profound: Why do our minds drift? If you have ever dabbled in mindfulness or meditation, you know this mind wandering has an almost gravitational pull. In fact, researchers now think we spend as much as 50 percent of our waking time in this state, which cognitive scientists have dubbed the brain's “default mode.”Today's guest is Vinod Menon. He's a giant in the field of cognitive science who played a central role in defining the brain “default mode network” back in 2003. In our conversation, he argues our tendency to daydream may be at the core of our self-identities, our creativity – and also many of our most troubling psychiatric disorders, from Alzheimer's to ADHD.Vinod Menon is Rachel L. and Walter F. Nichols, MD., Professor of Psychiatry & Behavioral Science at Stanford Medicine, and an affiliate of the Wu Tsai Neurosciences Institute.Learn MoreMenon's "Stanford Cognitive & Systems Neuroscience Laboratory"Stanford Medicine study identifies distinct brain organization patterns in women and men (Stanford Medicine, 2024)Children with autism have broad memory difficulties, Stanford Medicine-led study finds (Stanford Medicine, 2023)Interactions between attention-grabbing brain networks weak in ADHD (Stanford Medicine, 2015)Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. We want to hear from your neurons! Email us at at neuronspodcast@stanford.edu Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.

Send a textWhat if the behavior that broke your heart was actually the brain asking for help?In this episode Rayna sat down with author and advocate Lori Jones to explore the hidden contours of Huntington's disease, where genetics, uncertainty, and everyday caregiving collide and uncover the small, human choices that change everything.Lori grew up in an HD family, later becoming a legal guardian for her father through care homes, hospital handoffs, and hospice. She opens up about the emotional math of pre-symptomatic testing, the weight of a 50% genetic risk, and why learning about CAG repeats and symptom variability can bring clarity without stealing hope. We also trace powerful parallels with Alzheimer's: early psychiatric shifts that go unnoticed, late diagnoses that miss the window for treatment, and the hard truth that behavior often reflects brain change, not character.The heart of this conversation lives in the stories. A care home director who said we get creative and meant it. A third-shift art student sketching while Lori's dad savored ice cream, reconnecting with the artist he once was. A retired neurology chair arriving with a paper bag of fries, earning trust one salty bite at a time and clearing a path for much-needed meds. These aren't grand gestures; they're precise mercies that honor personhood and make care sustainable.Lori also names the quiet undertow of relief: survivor's guilt after testing gene negative. Her way through was service- organizing Team Hope fundraisers, writing Spared: A Memoir of Risk and Resolve, and speaking anywhere to help caregivers find language and community. If you've ever felt isolated, triggered, or unsure how to de-escalate fear-driven moments, you'll leave with practical tools, compassionate reframes, and a reminder that you're not supposed to carry this alone.Listen now, share this with someone who needs it, and tell us: what small act made a big difference in your caregiving? If this conversation helped, subscribe, leave a review, and pass it on so more caregivers can find hope and practical support.

What if healing does not begin with restriction, discipline, or a perfect diet, but with a simple nutritional shift that makes change feel possible instead of overwhelming?In this powerful and grounded conversation, I sit down with Adrienne Scharli, who was told she had an incurable neurological condition and went on to recover by addressing the root imbalances in her body through nutrition, lifestyle, and mindset.What makes this episode different is not just what she ate, but how she changed her diet. Adrienne shares a gentle, sustainable approach that removes overwhelm and allows healing habits to build naturally over time. This same principle shows up again and again across remission stories from cancer, autoimmune disease, neurological illness, and heart disease.This episode is for anyone facing a chronic or terminal diagnosis who feels frozen by fear, confused by conflicting advice, or exhausted by the idea of “doing everything perfectly.”In this episode, you'll discover:Why adding nourishing foods first can be more powerful than cutting foods outThe simple nutrition shift that helped Adrienne's symptoms resolve when nothing else workedHow gradual dietary changes can calm inflammation and support healing biology across many diseasesA step-by-step way to begin changing your diet without stress, guilt, or deprivationHow nutrition, mindset, emotional healing, joy, and nervous system regulation work together in real healing journeysThis is not a story about willpower. It is a story about creating an internal environment where healing becomes possible.Listen now to learn how one simple nutrition shift helped change the course of a devastating diagnosis and how you can begin applying the same approach today, no matter what illness you are facing.This episode will help you move out of fear, out of overwhelm, and into small, steady actions that support your body's natural capacity to heal.Learn more from Adrienne:web site: nourishyourway.comFacebook: MS Support - Heal & Reverse Multiple SclerosisYouTube: https://www.youtube.com/@adriennescharli_nourishDisclaimerThis podcast is for educational purposes only and does not offer medical advice. Always consult your licensed healthcare provider before making changes to your treatment or health regimen.This podcast explores stories and science related to cancer, MS, ALS, dementia, Alzheimer's, heart disease, autoimmune conditions, chronic illness, terminal diagnoses, integrative medicine, nutrition, lifestyle medicine, mind-body healing, remission, and quality of life, offering grounded hope and practical insight for anyone navigating a serious diagnosis.

No primeiro episódio de Alzheimer em foco, Danielle Calil, neurologista e editora médica do Portal Afya discute os avanços mais recentes no diagnóstico da Doença de Alzheimer (DA), com foco na incorporação de biomarcadores à prática clínica e no impacto das novas terapias modificadoras da doença.O que você verá neste conteúdo:• Transição do diagnóstico sindrômico para o modelo biológico• Biomarcadores no líquor, PET amiloide e tau• Avanços nos biomarcadores plasmáticos (p-tau217)• Modelo AT(N) e progressão da doença• Indicações clínicas para solicitação de biomarcadores• Impacto das terapias antiamiloide na jornada diagnóstica• Recomendações recentes da Academia Brasileira de NeurologiaDê o play e atualize sua prática clínica.

Music is medicine. It has the power to heal us. And today's guest knows it's something we can self-prescribe, for free, whenever we want to benefit. Dr Daniel Levitin is a neuroscientist, cognitive psychologist and bestselling author. He's also a former record producer and an accomplished musician who's brought all those skills together in his latest book, Music As Medicine: How We Can Harness Its Therapeutic Power. As soon as I heard about it, I had to ask Dan onto the podcast to share his wisdom. As a lifelong musician and music fan, I know certain tracks change how I feel. But talking to Dan has opened my mind to just how profound an effect music has on the brain. It doesn't just shift our mood, it can affect our entire physiology. Dan has spent decades studying this, advising the US Government and working with the National Institutes of Health, to the point where his research is now influencing global health policy. We've all experienced the health-giving power of music, perhaps without realising. Now with that knowledge, and Dan's insights, we can start to put it to therapeutic use. Here's what fascinates me the most: music doesn't just hit one part of your brain. Different types activate different regions, in much the same way as certain medications work. And Dan shares some astounding examples of this – from the people with Parkinson's who relearn to walk, to the marathon runners who don't feel pain, to the Alzheimer's patients who can't recognise loved ones, but can recall how to play an instrument perfectly. The brain regions that process music are deeper, older and more protected. It's why music communicates emotion in ways that words can't always match. Throughout our conversation, Dan makes this case that music is our birthright. And it can flood us with feelgood, bonding hormones. So it's a tool we can turn to for overcoming trauma, processing difficult feelings, or connecting with others. But he doesn't just want us to listen. Playing an instrument, singing and songwriting all do more than you might expect – and you don't need to be an expert. The next time I'm strumming my guitar, I won't just think of it as a hobby. I'll know I'm doing something profoundly important for my health. And you can too. Whether it's learning an instrument, having a family singalong in the car, or simply switching on the radio, I'm not sure there's a simpler, more effective way to feel better.   Support the podcast and enjoy Ad-Free episodes. Try FREE for 7 days on Apple Podcasts https://apple.co/feelbetterlivemore. For other podcast platforms go to https://fblm.supercast.com.   Thanks to our sponsors: https://vivobarefoot.com/livemore https://onepeloton.co.uk https://thewayapp.com/livemore https://drinkag1.com/livemore   Show notes https://drchatterjee.com/623   DISCLAIMER: The content in the podcast and on this webpage is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your doctor or qualified healthcare provider. Never disregard professional medical advice or delay in seeking it because of something you have heard on the podcast or on my website.

HEALTH NEWS A Simple Diet Change Could Slow Liver Cancer Brief, intensive exercise helps patients with panic disorder more than standard care Lucid dreaming could be used for mental health therapy, new study says US cancer institute studying ivermectin's ‘ability to kill cancer cells Too many saturated fats may be more harmful than too many refined carbohydrates.    Clips   Andrew Bridgen - https://x.com/ABridgen/status/2020573528571977993?s=20 MAHA Alliance Mike Tyson Super Bowl Commercial - https://www.youtube.com/watch?v=jg1SjFt1a_U   KETO DIET RISKS    The rationale for Keto Diet by its advocates Restricting carbohydrates, suppressing insulin and ketosis will lead to better metabolic heath, increase weight loss, reduce inflammation, and protect from chronic diseases.   Keto Claim: Carbohydrates raise insulin leading to fat storage – keto lowers insulin and burns body fat better Debunking: Ketosis is a metabolic state and not a health outcome. For example ketones can be elevated by very long fasting, starvation, different illnesses and uncontrolled diabetes.   Keto Claim: By minimizing carbs keto stabilizes blood sugar, reduce insulin spikes, and improve insulin sensitivity that benefits those with type 2 diabetes Debunked: This claim contradicts the evidence of induced hepatic insulin resistance and glucose intolerance in longer-term studies. In animal models, keto diets impair blood sugar regulation within several days, which shows harm for metabolic health.   Keto Claim: Ketones are seen as “clean” fuel that advocates claim are anti inflammatory and neuroprotective. Believe that this along with ketosis lowers triglycerides, raises HDL cholesterol, and improves lipid profiles. They argue that the increase in LDL cholesterol is benign. Claim saturated fats are harmless if carbs are low Debunked:  This claim is undermined by the increased LDL cholesterol, triglycerides, and cardiovascular risks from saturated fats in animal products. Meta-analyses show no long-term lipid improvements from keto diets. Rather this is the risk in elevated low-density lipoprotein and very-low-density lipoproteins that increase cardiovascular disease  Also, insulin reduction does not override the quality of fat. LDL cholesterol and ApoB, as well as atherosclerosis, increase significantly on an animal based diet. Saturated fat still remains a causal factor for cardiovascular disease.   Keto Claim: High protein and fat increases satiety and therefore reduces hunger Debunking: Weight loss is primarily from reduced intake due to satiety, not fat-burning efficiency. Long-term keto adherence often leads to weight regain with no significant sustained benefits for visceral fat or appetite control. hort term weight loss is not same as long term benefits. A study shows that weight loss at 3-6 months on a keto diet disappears by 12 months   Keto Claim: It enhances brain function and energy that then improves mental clarity and mood. Argue that animal products like eggs and organ meats provides choline and other nutrients for brain health. Debunked: There is no strong evidence for this claim. In fact keto's nutrient deficiencies and lack of fiber in the long term can lead to fatigue, constipation and in women neural tubal defects. Keto's claims are only based on short term trials.    Keto Claim: Use the evolutionary argument that humans evolved eating meat and fat – same argument the paleo folks used. Therefore, they believe keto diets align with human biology Debunked: A big study in Science in 2025 analyzed tooth enamel from skeletons of some of our oldest human ancestors, 3.5 million years ago, and found they ate predominately a plant based diet with no substantial sigh of mammalian meat. The isotopes matched herbivores (fruits, leaves and grasses, tubers, nuts, other vegetation) not carnivores.     Keto Diet Risks   It is worth noting, according to the Northwestern University Health site, there is a sizable drop out rate of participants in keto trials.   Although, there are studies that show keto does what it claims in the short term, there are no long-term human data to support their claims that an animal-based diet does this efficiently.   Important, research leans in the direction to indicate that keto's benefits – especially weight loss and glucose reduction, are transient and may not be directly related to animal food consumption itself but rather to calorie reduction and limiting glycogen.   Long term prospective studies and systematic meta analysis evaluations consistently show high red meat consumption, full-fat dairy and animal fats are associated with the following medical conditions. This is true even when carbohydrate intake is low   A good thorough study in JAMA shows that unprocessed red meat mildly increases all cause mortality – about 3-5% per 100 grams meat per day   High red and processed meat consumption increases carcinogenic N-nitroso compounds and heterocyclic amines that raise cancer risks by up to 18% per 50-100 grams/day – from meta analysis in the European Journal of Epidemiology   Dairy increases IGF-1 levels thereby too much calcium also suppressing Vitamin D and elevating prostate cancer risks by 79% per 400 gram dairy per day. Worse for processed meats that inreases risk by 21% per 20 grams/day – American Journal of Epidemiology   Red meat is linked to hormonal disruptions and carcinogens contributing breast cancer – European Journal of Cancer   Total unprocessed red meat consumption shows a modest 5% risk in pancreatic cancer per 100 grams/day. – From journal Clinical Nutrition   Many meta-analyses on meats have a relationship to stomach/gastric cancer, but processed meats are worse than unprocessed red meat. From study in Nutrients – 24 studies showed unprocessed red meat associated with gastric cancer by about 25% increase risk for every 100 grams/day.   Unprocessed red meat is linked to an 11% higher risk in overall cardiovascular disease risk due to inflammation and endothelial dysfunction. – from European Heart Journal   Saturated fats in meats increases non-HDL cholesterol and blood pressure and raises the risks of ischemic heart disease by 119% per 100 grams/day red meat – from American J Clinical Nutrition   Red meat diets reduce LDL Cholesterol much less than plant proteins and thereby increase atherosclerosis risks – from the journal Circulation   Red meats (an processed meats also in this study) contributes to insulin resistance via heme iron and raises Type 2 diabetes risks by up to 51% per 50 grams/day – International Journal Environmental Research in Public Health   Saturated fats in unprocessed red meat has a modest positive 12% increase with stroke risk – From  European Heart Journal Unprocessed poultry consumption shows a modest 4% increase in incident cardiovascular events per 100 grams/day. This is believed to be due to arachidonic acid poultry – in JAMA   Red meat contributes to sodium and saturated fat intact raising hypertension conditions by 14% per 50-100 gram/day – from journal Advanced Nutrition   Saturated fats from animal products cause lipotoxicity and insulin resistance, that promotes hepatic fat accumulation leading to non-alcoholic fatty liver disease – from Cardiovascular Development and Disease   High animal protein increases urinary calcium and acid overload leading to the formation of kidney stones – from the journal Nutrient   Animal-heavy diets have low fiber and micronutrient intake that contribute to nutrient deficiencies. Also causes constipation that can lead to immune system issues. – from the journal Nutrients   Red meat, dairy, and eggs disrupts the gut metabolism of carnitine and choline. This promotes TMAO plaque formation and inflammation that leads to atherosclerosis. – from Journal of Cardiovascular Development.   Although unprocessed meat consumption has not been adequately associated with dementia and Alzheimer's – yes, processed meats do – there are studies showing red meat is associated with “subjective cognitive decline” (SCD) which is related to precursors to dementia and Alzheimer's. A study in journal Neurology  links unprocessed red meat eaten at 1 or more servings per day to 16% higher risk in SCD.   High caloric density from saturated animal fats displaces fiber that contributes to weight gain obesity. From Neal Barnard in the American Journal of Clinical Nutrition   Animal products transmit prions that are associated with neurodegenerative disorders.  Proinflammatory compounds like TMAO are linked to neurological risks. – in International Journal of Molecular Science

Tom opens this week's livestream with updates and announcements:Registration remains open for the New Biology Experience at Polyface Farm (June 2026). Tom reminds the audience there's still time to sign up and join him, the New Biology Clinic team, and community members for a weekend of talks, food, music, and connection.New Biology Experience link here.In honor of Heart Month, DrTomCowan.com is offering a Heart Health Sale on:Hibiscus Concentrate and Human Heart, Cosmic Heart book.This sale ends TONIGHT at 11:59 PM PT.This week's science news includes:-A satirical open letter to Vernon Coleman and the announcement of his nomination for the “Put-sky Gas Bag of the Year” award-A Johns Hopkins study linking hydrogen sulfide (fart gas) to Alzheimer's prevention-A claim that the shingles vaccine slows aging and dementia-Evolution “going into overdrive” exactly 66 million years ago-A new mRNA-based sickle cell “cure” priced at $3 millionA thoughtful Q&A on:-Are chemtrails real? And if so, how should we go about detoxifying from chemtrails?-Is it OK to blend foods?-Why do people get kidney stones and what can you do to prevent them?-What are warts and what is their purpose?-Is shedding real?-What about cataracts?-Somebody asked about getting a superficial fungal infection—usually in places like your groin or your armpit, or sometimes what's called athlete's foot.Support the showWebsites:https://drtomcowan.com/https://www.drcowansgarden.com/https://newbiologyclinic.com/https://newbiologycurriculum.com/Instagram: @TalkinTurkeywithTomFacebook: https://www.facebook.com/DrTomCowan/Bitchute: https://www.bitchute.com/channel/CivTSuEjw6Qp/YouTube: https://www.youtube.com/channel/UCzxdc2o0Q_XZIPwo07XCrNg

Pete and Roger answer six listener questions covering Coast FIRE strategies with GIAs, US 401(k) tax implications in the UK, record keeping for IHT-exempt gifts, Australian pension taxation for UK residents, pension contributions to avoid the £100k tax trap, and managing a £2M portfolio as Power of Attorney. Shownotes: https://meaningfulmoney.tv/QA39    01:17  Question 1 Hi Pete and Roger, I'm 29 and working towards Coast FIRE within the next 2–3 years so I can begin a digital nomad lifestyle — working remotely while knowing my long-term retirement is taken care of. Right now, I've got: - £45k in a Stocks & Shares ISA - £25k in a workplace pension (via salary sacrifice) - A Lifetime ISA for a future house deposit (or later retirement) - A fully funded emergency fund I've already maxed out my ISA for this tax year and plan to continue doing that every year. But I have more money to invest now, and I know that to reach Coast FIRE on my timeline, I need to start using a General Investment Account (GIA). Here's where I'm stuck: I want to keep things simple and tax-efficient, but I feel a bit nervous about GIAs. I keep hearing about the "bed and ISA" strategy but don't really understand how it works in practice or how to implement it over time. Could you explain: - How best to use a GIA alongside an ISA when working towards FIRE? - How to manage capital gains and dividend tax efficiently? - And how the bed and ISA approach actually works — especially for someone trying to keep things simple? Thank you both so much — your podcast has been an incredible resource and a big part of why I've been able to take control of my finances. Warmly, Pauline 12:22  Question 2 Hello Pete & Roger I am very late convert to the podcast but have been ploughing through the Q&A for a few days now. I think I only have another 592 episodes to get through so should be up to date by the end of the week !! I am not sure whether this has been covered or not. I have a 401K plan that has been hibernating in the USA for 20 years. I have only recently started looking at it and now need to understand the tax implications. I have tried to read HMRC guidelines on tax treaties etc but get even more confused than before. My current belief is that the provider will pay this money out by means of US issued cheque (not a problem) but withhold 30% tax (a problem). How will HMRC treat this? The usual sources http://unbiased.co.uk for one run for the hills on finding information about this, is this an area you can provide guidance, but obviously not advice as I know you cannot through the podcast. Regards, Stephen 16:10  Question 3 Hi Pete & Roger, Like so many people I am really impressed, not just with your knowledge and great communication skills, but that you put out such life changing content. You're providing us with the means to help ourselves in this financial world as well as letting us know when to seek professional help. On to my question: we're (wife and I) retired (late-60s) and are lucky enough to have more than enough to comfortably live on, thanks to DB & state pensions, house price inflation etc. Not really through any financial planning but just having been born at the right time! So we do now have an IHT liability. We have a joint second death Whole Of Life policy (in trust) in place for potential IHT and have given help with house deposits for our children. We also are gifting to the kids out of our excess income and would like your thoughts on the type of record keeping needed for this. We have letters stating the intention to give the gifts, recording who to etc. We keep completed IHT403 forms which we update annually. We also have a monthly/annual spreadsheet of income/expenses which demonstrates our surplus and keep track of expenses with the MeMo transaction tracker (thanks for that). These are all in our 'WID' file (again thanks to you for that). What we're not sure about is any documentation that might be needed to evidence the figures. Income is straightforward with P60s, statements of interest/dividends. However, what is required for expenses? Can't really keep all supermarket receipts etc and even bank/credit card statements would be quite bulky over several years. Not sure if we're overthinking but don't want to leave a difficult task for our kids when we're gone. Thank you both again for all the good you are doing Simon 20:33 Question 4 Brian (in Australia) Thank you for all your podcasts and videos but I think I may have to sign up to the academy to fully get my head around all the UK rules. We are looking to move to the UK from Australia - we have no UK govt pension entitlements but are retired with personal Australian private superannuation account pensions. The pension income payments and withdrawals are all tax free in Australia but will the UK government apply a tax on these pension payments once we are UK residents?   Thanks again for all your useful information. Regards, Brian 22:55  Question 5 Hi Roger (and Pete), I had a question which is boiling my brain far more than it should and I was hoping you could include it in one of your Q&A episodes. I'm in the fortunate position of being caught by the £100k 'tax trap' due to being paid a bonus for the first time in a number of years. This particular first-world problem is being made all the worse because my daughter will start nursery next year so in addition to the 60% tax charge on my bonus, we would also lose the 30 free hours of childcare we currently have access to. I currently salary sacrifice roughly £5,000 of salary into my pension (which my employer matches) and this holds my income at £99,000. However there is no option for me to do any kind of 'bonus sacrifice'. My only choice is to receive the bonus payment net of tax & NI through PAYE and then make a payment into my personal pension (a Vanguard, low cost multi-asset fund, just like you taught us!). I think I'm right in saying my pension provider will claim back the basic rate tax automatically for me, and I can then claim back the other 20% via my tax return with HMRC paying this extra 20% back to me directly. So far so easy, but what I can't work out is just how much I have to pay in to my pension in order to take all of the bonus payment out of my taxable income. Presumably its not the net amount extra that gets paid into my bank account on the month my bonus is paid because this will also be net of NI, meaning I wouldn't have paid enough in to avoid the £100k trap. Assuming my bonus payment was £10,000 (I don't know the exact figure yet but its likely to be around this amount), could you talk through how to calculate the net payment I need to make into a personal pension to achieve the desired result? As a follow up to this, if HMRC send me a cheque (very 1990's) for say £2000 of refunded higher rate tax, do I need to pay this into my pension in the next tax year to avoid having it counted towards my taxable income in that financial year? Please keep up the great work that you both do, you've really helped me get my financial life in order after an extremely difficult period in my life. Thank you both! Jimmy 27:29  Question 6 Hi Pete and Rog, Firstly, a huge thank you for all the insight and support you continue to offer. The impact of the Meaningful Money Podcast is immense—I've personally benefited so much from your free content over the years. I'll keep this as brief as I can: My great aunt (now 84) has built a substantial portfolio over decades—about £2 million across ~60 individual company shares, with approx. £1.3 million in a GIA and the rest in S&S ISAs. She also holds £400k in fixed-term bonds, savings accounts, and premium bonds. Sadly, she was diagnosed last year with dementia and Alzheimer's and now resides in a care home. I am her Power of Attorney and want to act in her best interests—simplifying her affairs and ensuring tax efficiency, especially regarding her legacy. She has no spouse or children but wishes to leave money to nieces, nephews, and charities. Here's my working plan: - Offset gains in the GIA by selling loss-making investments (totalling £30k–£40k) alongside some of the profit making investments to reduce market exposure without incurring CGT costs.     - Liquidate all shares in her S&S ISAs and transfer funds into cash ISAs with decent interest rates - Leave most of the GIA portfolio untouched to benefit from the CGT uplift on death Am I broadly on the right track for tax efficiency and sensible financial planning? Should I seek formal advice to ensure I'm doing the best by her? Thanks again for all you do—it really matters. Best regards, Josh  

This week on the podcast, AgingIN CEO Susan Ryan is joined by Susie Singer Carter, a filmmaker, advocate, and caregiver, who shares her deeply personal journey into caregiving—and how it transformed her life, her work, and her mission. Inspired by her mother's 16-year battle with Alzheimer's disease, Susie recounts moving from "caregiver by surprise" to outspoken advocate for systemic reform in long-term care. Her mother, Norma Pecora, a former opera singer and art dealer, wasdiagnosed at age 72. Norma lived with Susie for a year following the death of her husband—an experience that was both profoundly challenging and unexpectedly beautiful. That journey ultimately led to Susie's award-winning documentary, "No Country for Old People," which exposes the harsh realities of institutional long-term care, including chronic understaffing, neglect, and a lack of transparency and accountability. The film has since become a catalyst for national conversation and action. Susie also discusses how her advocacy grew from grief, leading to the creation of the ROAR movement—a growing effort to raise public awareness, empower families, and push for legislative change to protect older adults and other vulnerable people in care settings. This episode is a powerful exploration of love, loss, rage, resilience, and the urgent need to reimagine how we value and care for older people. Watch the film HERE on Amazon Prime.

In this episode, Steve and Virginia speak with elder law attorney Fay Blix about the critical importance of early legal planning after an Alzheimer's diagnosis. Fay explains how stigma, fear, and denial often delay planning, and emphasizes involving the diagnosed person in decisions while they still have capacity. She outlines key tools such as durable powers of attorney, advance healthcare directives, and POLST forms, stressing that documents should be clear, personalized, and regularly updated. Fay also discusses the emotional and logistical challenges families face, the value of open communication and defined roles, and why conservatorship, though sometimes necessary, can be costly and intrusive. Her core message: proactive legal planning helps protect dignity, reduce stress for caregivers, and ensure a person's wishes are honored as the disease progresses.Send a text

DO NOT skip this episode because you think you're “too young” to worry about dementia ⚠️Max Lugavere, New York Times bestselling author and host of The Genius Life podcast, blows up everything we've been told about brain health. After watching his mother battle dementia, Max went deep into the research and found something shocking: Alzheimer's may be largely preventable. In this episode learn exactly how to prevent Alzheimer's and dementia, or slow it down if a loved one has already been diagnosed. Learn groundbreaking news about Parkinson's, the nuanced truth about nicotine, why mouthwash should be avoided, and if eggs are a superfood or a super don't. Max also shares his political journey.Thank you to our sponsors!TAYLOR DUKES WELLNESS: Use code "ALEXCLARK" for 10% off your purchaseA'DEL NATURAL COSMETICS: Use code "ALEX" for 25% off first-time ordersCALIFORNIA MOBILE ACUPUNCTURE: Visit us online or check our Scottsdale locationJOOVV: Get an exclusive discount on your first red light therapy orderPRIMALLY PURE: Use code "ALEXCLARK" for 15% off your first orderJASPR: Use code "ALEX" to get $400 off your purchaseOur Guest:Max LugavereMax's Links:WebsiteInstagramYouTubeFacebookPodcastDocumentary

All Home Care Matters and our host, Lance A. Slatton were honored to welcome Ann Campanella as guest to the show.   Ann Campanella is a former magazine and newspaper editor and is the author of three memoirs and four collections of poetry. Her award-winning writing has appeared in newspapers, magazines, literary journals and online sites across the country and around the world. Her first memoir, Motherhood: Lost and Found, was named "One of the best Alzheimer's books of all time" by BookAuthority two years in a row.   Since 2017, Ann has been a manager/director of AlzAuthors.com, a nonprofit organization with the mission of sharing Alzheimer's and dementia resources to light the way for others. In 2018, she was recognized by her hometown newspaper as one of the Most Influential Women in her community for her work promoting Alzheimer's awareness.   Ann's second memoir, Celiac Mom, won the 2024 Silver Medal in the Nonfiction/Health category of the Readers' Favorite International Book Award. This book has become a "go-to" resource for the celiac community.   A social-media influencer, Ann uses her Instagram account @glutenfreeforgood to spread awareness about this condition. Ann's most recent book, The Shoulder Season: A Memoir of Fracture and Grace, shares her experience of going from a caregiver to someone who needed care after a serious injury.   Ann hopes it will provide hope and inspiration to those facing a season of health challenges. Ann and her husband live on Lake Norman in North Carolina and enjoy nightly sunsets.     About "The Shoulder Season":   After decades of being physically fit, riding and training horses, Ann's life skids to a stop when a seemingly innocuous accident (tripping over the dog) turns into a traumatic injury that shrinks her world. She succumbs to severe pain and faces difficult surgeries that require a two-year recovery.   On the brink of an empty nest, a few months before the pandemic, Ann is no longer the busy caregiver who juggles her family's needs along with her writing work and caring for her farm but becomes the person who needs care. Ann must discover a new identity and reimagine her future.   The Shoulder Season serves as a guide and an inspiration for those facing a life interrupted.    

Walking 5,001 to 7,500 steps a day slows the buildup of tau, the brain protein linked to Alzheimer's-related decline, helping you stay sharper for years longer Older adults with elevated amyloid — a key early Alzheimer's marker — preserved memory and daily function far better when they consistently reached a moderate step range Even small increases in movement, such as moving from under 3,000 steps to 3,500 to 5,000 per day, deliver meaningful cognitive benefits without requiring intense exercise High-intensity training pushed healthy adults into metabolic dysfunction, reducing mitochondrial energy production by about 40% and disrupting blood sugar stability Finding your personal exercise "sweet spot" — enough movement to avoid inactivity without pushing into extreme training — protects both long-term brain health and daily metabolic balance

The peptide industry just hit $328 million in imports from China in nine months, and the fastest-growing buyers aren't bodybuilders. They're women in their 30s, 40s, and 50s who were told their labs look "fine" when they know something is deeply wrong.In this episode, I break down why peptides like BPC-157 and TB-500 are being aggressively marketed to women in perimenopause, why there isn't a single randomized controlled trial proving they're safe or effective in humans, and what the actual evidence says about brain fog, muscle loss, joint pain, and metabolic decline. I explore why the "your bloods are normal" dismissal has destroyed women's health, how hormone replacement therapy actually protects your brain when timed correctly, why GLP-1s work when peptides don't, and what protein, sleep, and resistance training do that no research chemical can replicate, because the foundations of brain health will never trend on TikTok, but they're the only things backed by decades of rigorous science. *Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: * https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. *TOPICS DISCUSSED* 00:00 Intro: Why women are the fastest-growing peptide buyers 07:01 Perimenopause reality: why "your labs look fine" is destroying women's health 15:20 What peptides actually are and the missing human evidence 31:00 Quality control disasters and documented side effects 39:50 What actually works: resistance training, protein, and muscle preservation 44:30 Hormone replacement therapy and brain protection 51:14 GLP-1 receptor agonists: evidence-based use vs. gray market risks *Thank you to our sponsors* Caraway: https://carawayhome.com/neuro10 Timeline Mitopure: http://timeline.com/NEURO Function Health: https://www.functionhealth.com/tcm/louisanicola _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

America Out Loud PULSE with Dr. Myriah Hinchey – Lyme disease and other vector-borne infections can masquerade as psychiatric and neurodegenerative illness when they go undetected. This piece examines why these conditions are frequently missed, how symptoms resemble dementia and Alzheimer's disease, and why timely clinical recognition and informed testing can alter disease trajectory and improve outcomes...

🗣️ Your Voice: The Newest Tool in the Fight Against Alzheimer's Getting an early diagnosis for dementia is often a slow and painful process. Many families wait years for answers, missing the chance for early intervention and better outcomes. However, what if the first warning signs are hidden in the way you speak? This episode explores a revolutionary breakthrough in early diagnosis using voice biomarker technology. By analyzing brief speech samples, AI can now detect subtle neurological changes with incredible accuracy. This non-invasive method removes the high costs and long wait times typically associated with clinical screenings. Consequently, it brings the power of early diagnosis directly into your home. We discuss how this tool identifies Mild Cognitive Impairment before traditional symptoms even appear. Discover why your smartphone might be the key to protecting your brain health. Ultimately, this innovation provides the clarity needed for early diagnosis, helping you take control of your future today. ⏱️ Episode Timestamps 45:50 – Special Offer: How to access the voice screening tool today. 00:00 – The "Invisible" Barrier: Why early dementia screening is failing. 04:15 – The Training Gap: Why many doctors miss early cognitive signs. 08:30 – From Loneliness to Labs: The origin story of Mamsa's technology. 12:45 – Reminiscence Therapy: Using the phone to strengthen cognitive pathways. 17:10 – The Science of Sound: How 45 seconds of speech reveals brain health. 22:50 – 94% Accuracy: Breaking down the data behind voice biomarkers. 27:15 – The Stigma Problem: Why people avoid seeking a diagnosis. 31:40 – Sleep & Stress: Can being tired cause a false positive? 36:20 – How voice biomarkers are being used in clinical trials and clinics. 41:05 – The Future of Brain Health: Simple steps for self-observation. _____________________________________________________ Our Guest: Andre Hrmo Andre Hrmo is a 23-year-old visionary dedicated to tackling one of the world's most heartbreaking health challenges: cognitive decline and Alzheimer's disease. Driven by purpose, he has immersed himself in understanding why these conditions are on the rise, why cutting-edge therapies often fall short, and how technology can finally make a profound impact. His mission centers on early detection, operating under the crucial premise: you cannot treat what you cannot detect. As the founder of his company, Ondrej is actively working to dismantle the barriers surrounding cognitive screening, striving to make it accessible, affordable, and entirely stigma-free by bringing it directly into people's homes. Furthermore, his commitment extends beyond diagnostics. He is keenly interested in the complex relationship between social isolation, loneliness, and the accelerated progression of dementia. Ondrej is continuously exploring innovative technological solutions to address these emotional and social factors as well. ++++++++++++++++++++++++++++++++++++++++ Related Episodes: New Alzheimer's Treatment? Impact Inflammation. Memories & Brain Health: The Science of Bioelectric Medicine ++++++++++++++++++++++++++++++++++++++++ Sign Up for more Advice & Wisdom - email newsletter. ++++++++++++++++++++++++++++++++++++++++ Make Your Brain Span Match Your LifeSpan Relevate from NeuroReserve With Relevate nutritional supplement, you get science-backed nutrition to help protect your brain power today and for years to come. You deserve a brain span that lasts as long as your lifespan. ++++++++++++++++++++++++++++++++++++++++ Please help us keep our show going by supporting our sponsors. Thank you. Stop 100% of Unwanted Calls with imp. Did you know people with Alzheimer's can receive nearly 200 spam calls a week? You can put a stop to those now. ++++++++++++++++++++++++++++++++++++++++ Join Fading Memories On Social Media! If you've enjoyed this episode, please share this podcast with other caregivers! You'll find us on social media at the following links. Instagram Twitter LinkedIn  Facebook Contact Jen at hello@fadingmemoriespodcast.com or Visit us at www.FadingMemoriesPodcast.com

Roughly 90% of Alzheimer's patients develop neuropsychiatric symptoms including anxiety, persistent fear, and an inability to recognize safety — but little research is being done to investigate why. New data connecting PTSD, trauma, and accelerated brain aging may hold the answer.Dr. Caesar Hernandez is a behavioral, molecular, and circuit neuroscientist and assistant professor in the Division of Gerontology, Geriatrics & Palliative Care at the University of Alabama at Birmingham. His research program seeks to identify modifiable mechanisms that drive vulnerability to age-related cognitive decline and Alzheimer's disease.In this conversation with Dr. Dominic D'Agostino, Dr. Hernandez walks through epidemiological evidence linking PTSD to increased Alzheimer's risk, the comorbidity cluster of metabolic syndrome, gut permeability, and neuropsychiatric disorders observed in veteran populations, and why ketogenic interventions may offer a unique therapeutic angle — reducing neuroinflammation and anxiety while making the brain more receptive to rewiring traumatic memories.Questions Answered in This Episode: Could addressing PTSD in midlife meaningfully reduce the risk of cognitive decline and dementia later in life?Why do veteran populations show such high comorbidity between PTSD, metabolic syndrome, and dementia? Could ketogenic therapy serve a similar function to pharmacologically-assisted psychotherapy for PTSD? How does the amygdala - the brain's "fear center" - play a role in Alzheimer's disease? What is the single biggest unanswered question driving Alzheimer's research right now — and why does it go beyond genetics and biochemistry?Dr. Hernandez's driving question — why are negative life experiences associated with an increased the risk of neurodegeneration? — reframes brain aging as something shaped not just by genes and biology, but by the lives we live and the stress we carry.Find more of Dr. Caesar Hernandez online:University of Alabama BirminghamLinkedInSpecial thanks to the sponsors of this episode:✅ Genova Connect – Get 15% off any test kit with code METABOLICLINK here.✅ Fatty15 – Get 15% off a 90-day Starter Kit with code METABOLICLINK here.✅ Troscriptions – Get 10% off your first order with code METABOLICLINK here.✅ ZocDoc - Find and instantly book a top-rated doctor here.In every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

Mark Burnett is a former database programmer who turned his problem-solving brain towards his own health after being diagnosed with neurological disorders. He is also the president of APDI, which stands for Alzheimer, Parkinsons, and Dementia, and the founder and owner of My Brain Restore.    Born in 1958 at Camp Lejeune, Mark made the connection between his long-term symptoms to environmental exposure. He now shares his research-driven approach to brain restoration, system tracking, and resilience under uncertainty.  Mark shares his own journey of dealing with Alzheimer's, Parkinsons, and Dementia, and given no hope for recovery from traditional medicine. Basically, he was given a death sentence, being told that his symptoms would continue to worsen and his level of function would continue to deteriorate until the time of his death. Mark took matters into his own hands, dedicated himself to relentless research, and ultimately led him to launch My BRAIN RESTORE™, a premium new nutraceutical explicitly developed to support those facing neurological challenges — the same as he does, including his Parkinson's, Alzheimer's (a form of dementia). He shares his incredible story along with his amazing progress and decrease of his symptoms once he began taking the product, along with the blatant skepticism he received from some of his physicians and other medical professionals. He also describes how he went from being a coach potato to running a marathon for the first time in his life. Download this fascinating, positive, and uplifting episode with its positive message of health, hope, and healing for anyone dealing with neurological disorders, especially those who have been told that there is no hope.      Connect with Mark: https://mybrainrestore.com/ https://www.facebook.com/profile.php?id=61577796490045 https://x.com/mybrainrestore https://www.youtube.com/@MyBrainReStore https://www.instagram.com/mybrainrestore/ Want to be a guest on TheFemiNinjaProject? Send Cheryl Ilov a message on PodMatch, here: https://www.podmatch.com/hostdetailpreview/1620842117560x116520069523704300

Trenes operan con normalidad hoy 10 de febrero tras desconvocarse la huelga por acuerdo con el Ministerio. Miles de vecinos siguen sin regresar a sus casas por el temporal, que mejora en Extremadura pero mantiene 32 colegios cerrados en Andalucía. La Fiscalía pide absolución de Íñigo Errejón en el caso Elisa Moulía, quien continúa su denuncia. Un estudio de Harvard indica que 2-3 tazas de café diarias reducen un 18% el riesgo de demencia o Alzheimer. Duolingo ve un 35% de aumento de estudiantes de español tras la Super Bowl con Bad Bunny. En

In this episode we welcome Dr. Nathan S Bryan, a trailblazer in the realm of biomedical research, with a specific focus on the life-sustaining molecule, nitric oxide.  Dr. Bryan delves into the profound impact of nitric oxide on health and longevity. They explore how this naturally produced gas, often misunderstood yet vital, fuels bodily functions, increases lifespan, and underpins a host of health processes - from maintaining blood pressure to enhancing human performance. Dr. Bryan, with his extensive experience and pioneering research, unpacks the myths surrounding nitric oxide, shedding light on its critical role in averting chronic diseases and promoting overall wellness.Listeners are introduced to the wide-ranging implications of nitric oxide deficiency, which can lead to issues such as erectile dysfunction, metabolic disease, exercise intolerance, brain fog, and even Alzheimer's. Dr. Bryan emphasizes eliminating factors that hinder nitric oxide production, such as mouthwash, fluoride, and antacids, and advocates for a proactive approach to health. His aim to educate is underscored by the introduction of supplements designed to boost nitric oxide levels, offering a path to reclaiming vitality and improving the quality of life. This is a must-listen episode for anyone interested in cutting-edge health insights and longevity.Timestamp Summary3:27 The Importance of Nitric Oxide in Human Health6:44 The Importance of NO in Respiratory Health12:30 Understanding Nitric Oxide's Role in Cardiovascular Health15:48 Nitric Oxide's Potential in Treating Alzheimer's and Dementia18:11 Nitric Oxide Deficiency and Erectile Dysfunction Solutions22:53 Nitric Oxide in Chronic Disease Management25:21 Improving Nitric Oxide Production by Avoiding Common Inhibitors28:09 The Dangers of Antacids and the Importance of Nitric Oxide33:53 The Conflict Between Misinformation and Science in Nutrition36:03 The Importance of Nitric Oxide in Longevity and Health40:10 The Discovery and Impact of Nitric Oxide in Medicine44:35 The Benefits and Applications of Nitric Oxide SupplementsFor products and more information: n101.comSponsor for this podcast: AirDoctor If you want to upgrade the air in your home,   Head to AirDoctorPro.com and use promo code transform to get UP TO $300 off today!  Breathe better. Live better.” See this video on The Transform Your Mind YouTube Channel https://www.youtube.com/@MyhelpsUs/videosTo see a transcripts of this audio as well as links to all the advertisers on the show page https://myhelps.us/Follow Transform Your Mind on Instagram https://www.instagram.com/myrnamyoung/Follow Transform Your mind on Facebookhttps://www.facebook.com/profile.php?id=100063738390977Please leave a rating and review on iTunes https://podcasts.apple.com/us/podcast/transform-your-mind/id1144973094 https://podcast.feedspot.com/personal_development_podcasts/ For sponsored Brand interviews and sponsorship inquires please visit Partner With The Transform Your Mind Podcast | Myrna Young Life Coach

Boosting a Natural Molecule (NAD+) Reverses Alzheimer's Brain Damage in New Study University of Oslo & Ullevaal University Hospital (Norway), February 8, 2026   One of the key drivers of brain dysfunction in Alzheimer's disease (AD) is the protein tau. Under normal conditions, tau helps maintain the internal structure of neurons, supporting the transport systems that allow nerve cells to function properly. In Alzheimer's disease, however, tau becomes abnormally modified and begins to clump together. These aggregates interfere with normal cellular transport, damage neurons, and ultimately contribute to memory impairment. Now, an international team of scientists has identified a previously unrecognized way to protect the brain from this degeneration. Their research shows that increasing levels of the naturally occurring molecule NAD⁺ can counteract neurological damage linked to Alzheimer's disease.  Previous research has suggested that boosting NAD⁺ using precursor compounds such as nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN) can produce beneficial effects in animal models of AD and in early-stage clinical studies. However, the biological processes responsible for these effects have remained poorly understood,” explains first author Alice Ruixue Ai. The new study reveals that NAD⁺ works through a previously unidentified RNA-splicing pathway. This pathway is regulated by a protein called EVA1C, which plays an essential role in the process of RNA splicing. RNA splicing allows a single gene to produce multiple isoforms of a protein, and one isoform may show distinctive effects on the other isoforms. Its dysregulation is one of the most recently acknowledged risk factors for AD.