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This is one of the BEST interviews we've ever done on supplements and cutting-edge supplement technology... We had Dr. Scott Sherr on the podcast — a board-certified internal medicine physician who practices health optimization medicine and hyperbaric oxygen therapy. This guy KNOWS his stuff and we break down some of the most powerful compounds you can get your hands on to improve cognitive function, athletic performance, and longevity. Here's the reality... 94% of US adults are metabolically UNHEALTHY. That means your mitochondria — the powerhouses of your cells — are struggling to produce the energy you need. Dr. Sherr explains exactly why this happens, how it connects to everything from anxiety and depression to fat loss struggles, and what you can actually DO about it. We dive DEEP into methylene blue — the first drug ever registered with the FDA back in 1897 — and why it's become one of the most powerful tools for supporting mitochondrial function and energy production. But it doesn't stop there... We cover the GABAergic system and why most people are walking around GABA deficient (hello anxiety, insomnia, and mood issues), the synergy between methylene blue and red light therapy, how to use these compounds for travel, and a complete sleep optimization stack that could finally get you those 90+ Oura Ring scores. If you're tired of being tired, stressed about being stressed, or just want to understand how to actually support your body at a cellular level — this episode is a MUST listen. MAPS PPL — https://mapsppl.com (code: ppl) SPONSORS Troscriptions — https://troscriptions.com/mindpump (code: mindpump) Seed — https://seed.com/mindpump (code: 25mindpump) 00:00 — Intro 5:56 — Dr. Scott Sherr's background and health optimization medicine framework 10:42 — Strengths and weaknesses of conventional vs alternative medicine 16:34 — Why 94% of US adults are metabolically unhealthy 22:30 — The 'sympathetic spiral of doom' and why doing MORE isn't better 25:48 — Deep dive into methylene blue — history and mechanisms 35:09 — MAO inhibition, serotonin syndrome risk, and dosing protocols 42:43 — Methylene blue and red light therapy synergy 48:55 — GABA system, B3-GABA, and the TroCalm formula explained 59:58 — Complete sleep optimization stack and nighttime routine 67:30 — Cordycepin benefits and immune support protocols PEOPLE MENTIONED Dr. Scott Sherr — Guest — board-certified internal medicine physician, health optimization medicine practitioner, co-founder of Troscriptions Dr. Ted Achacoso — Founder of Troscriptions and the Health Optimization Medicine nonprofit, mentor to Dr. Sherr Alan Sherr — Dr. Sherr's father — chiropractor for 45+ years who influenced his alternative medicine philosophy Francisco Gonzalez Lima — Researcher at University of Texas Austin studying methylene blue for Alzheimer's, TBI, and stroke Thomas DeLauer — Mutual friend who uses methylene blue 2-3 times per week on high-stress days Paul Stamets — Referenced regarding mushroom knowledge and Amanita Muscaria/Santa Claus connection
You don't understand aging. You've been lied to about what's possible for the human body. You think the march toward old age and disease is inevitable, and that genetics are your destiny. The reality is, we're living through the greatest turning point in the history of human health—and most people have absolutely no idea just how fast it's all happening. What if I told you that not only can we slow the aging process, but that it's starting to look like we can actually reverse it? Thanks to the exponential power of AI and the most cutting-edge biotechnology, what used to take centuries and cost billions is now possible in months, for a fraction of the price. Today on Impact Theory, we are joined by a true pioneer who's redefining what it means to get old—someone at the intersection of AI, biology, and longevity: researcher, Harvard professor, and world-renowned expert on aging, Dr. Sinclair. Strap in, because this episode is packed with groundbreaking science, jaw-dropping experiments, and a vision for the future that will challenge everything you think you know about what it means to stay young. Let's dive in. What's up, everybody? It's Tom Bilyeu here: If you want my help... STARTING a business: join me here at ZERO TO FOUNDER: https://tombilyeu.com/zero-to-founder?utm_campaign=Podcast%20Offer&utm_source=podca[%E2%80%A6]d%20end%20of%20show&utm_content=podcast%20ad%20end%20of%20show SCALING a business: see if you qualify here.: https://tombilyeu.com/call Get my battle-tested strategies and insights delivered weekly to your inbox: sign up here.: https://tombilyeu.com/ ********************************************************************** If you're serious about leveling up your life, I urge you to check out my new podcast, Tom Bilyeu's Mindset Playbook —a goldmine of my most impactful episodes on mindset, business, and health. Trust me, your future self will thank you. ********************************************************************** FOLLOW TOM: Instagram: https://www.instagram.com/tombilyeu/ Tik Tok: https://www.tiktok.com/@tombilyeu?lang=en Twitter: https://twitter.com/tombilyeu YouTube: https://www.youtube.com/@TomBilyeu Blinkist: Start your free trial at https://blinkist.com/impactQuince: Free shipping and 365-day returns at https://quince.com/impactpodIncogni: Take your personal data back with Incogni! Use code IMPACT at the link below and get 60% off an annual plan: https://incogni.com/impactAT&T Business: Switch to AT&T Business at business.att.comNetsuite: Right now, get our free business guide, Demystifying AI, at https://NetSuite.com/TheoryKetone IQ: Visit https://ketone.com/IMPACT for 30% OFF your subscription orderSumm: code TOMVIP20 for 20% off your first year at https://summ.com?via=tombilyeu&coupon=TOMVIP20Shopify: Sign up for your one-dollar-per-month trial period at https://shopify.com/impactCozy Earth: code IMPACT for 20% off https://cozyearth.comQuo: Try for free PLUS get 20% off your first 6 months at https://quo.com/impact Learn more about your ad choices. Visit megaphone.fm/adchoices
Lo sits down with a very special guest this week, a pioneering neurologist who doesn't just study the brain, he's spent decades figuring out how to protect it. Dementia is on the rise so it's the perfect time to level up our brain health. In a conversation that's equal parts fascinating and practical, they unpack what's actually happening inside your brain on a daily basis—what's helping it thrive, what's quietly damaging it, and the habits most people don't realize are accelerating cognitive decline.Without getting overly clinical, the episode breaks down the real reasons dementia and Alzheimer's cases are rising—and more importantly, what you can start doing now to lower your risk. From brain fog to memory lapses to long-term brain health, this is one of those conversations that shifts how you think about your body… and your future.It's insightful, eye-opening, and surprisingly actionable, because taking care of your brain isn't just about aging, it's about how you show up right now.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this powerful and heartfelt episode of Kingdom Crossroads, T.S. Wright sits down with Christian author and educator Kathy Dye to explore how God uses life's most difficult seasons to shape purpose, legacy, and faith.Kathy shares her deeply personal journey—from growing up in a ministry family to spending nearly three decades in education and ultimately stepping into writing. Her inspiration for her first book, A Song in Her Heart, was born through walking alongside her mother's battle with Alzheimer's, where she witnessed how music and faith remained even when memory faded.Together, they discuss how God places a unique “song” in every believer—one that can still be expressed even in suffering, loss, and uncertainty.Key Topics CoveredGrowing up in a multi-generational Christian householdThe impact of Alzheimer's and faith in difficult seasonsHow storytelling reflects the teaching style of JesusWriting children's books with biblical principlesThe importance of legacy and passing faith to the next generationKathy's upcoming Bible study: The Song in Our HeartThe “S.O.N.G.” Bible study method:S – ScriptureO – ObservationN – Nesting (personal reflection)G – GrowthFeatured Books by Kathy DyeA Song in Her Heart – Helping children understand Alzheimer's through faithKit Kat Camp: No Electronics – Encouraging imagination and unplugged livingKit Kat Camp and the Grumpy Neighbor – Teaching empathy and understanding othersKey TakeawayEven in life's hardest moments, God remains our strength and our song. When we root ourselves in Him, our story becomes a testimony that can impact generations to come.Connect with Kathy DyeWebsite: kathydyeauthor.comAvailable on AmazonFollow on Facebook & Instagram for updates and encouragementCheck out this link to view Kingdom Cross Roads on TV.https://jesussaid.tv/?affiliate=tswright_gccTo get a copy of our new book "Embracing the Truth" or to have TS Wright speak at your event or conference or if you simply want spiritual or life coaching or just a consultation visit:www.tswrightspeaks.comVisit our website to learn more about The God Centered Concept. The God Centered Concept is designed to bring real discipleship and spreading the Gospel to help spark the Great Harvest, a revival in this generation.www.godcenteredconcept.comKingdom Cross Roads Podcast is a part of The God Centered Concept.Call to ActionIf this episode encouraged you, be sure to subscribe, leave a review, and share it with someone who needs hope today.Hashtags#ChristianPodcast #FaithJourney #KingdomCrossroads #KathyDye #ChristianAuthor #BibleStudy #FaithInHardTimes #AlzheimersAwareness #ChristianLiving #Discipleship #ChristianBooks #SpiritualGrowth #FaithAndHope #JesusIsLord #NextGenerationFaith
"The science is undeniable...every single chronic disease results from a lack of nitric oxide production." -Dr. Nathan Brya Dr. Nathan S. Bryan is a leading biochemist specializing in nitric oxide research with over 25 years of groundbreaking contributions to molecular medicine. He received education and training at esteemed institutions such as UT Austin, LSU School of Medicine, and Boston University, and later joined UT Health's faculty through the recruitment of Nobel laureate Ferid Murad. As the founder and CEO of Bryan Therapeutics, Dr. Bryan has been pivotal in developing nitric oxide-based therapies for conditions such as heart disease, Alzheimer's disease, and chronic wounds. His consumer products have gained international recognition, making him a pioneer in nitric oxide therapy and molecular medicine innovation. Episode Summary: Welcome to another insightful episode of "All My Health, There Is Hope," where host Jana Short welcomes Dr. Nathan S. Bryan, a world-renowned biochemist and nitric oxide expert. In this episode, Dr. Bryan shares his professional journey and how his unwavering hope and faith have propelled his research and innovations forward in the field of nitric oxide therapies. As a pioneer in this area, Dr. Bryan elaborates on the critical role nitric oxide plays in cardiovascular health, energy production, and overall well-being. Delving deeper, Dr. Bryan discusses his mission to disseminate the science of nitric oxide and its implications on health and longevity. As he differentiates nitric oxide products backed by solid research from the questionable ones populating the market, he stresses the importance of informed choices when it comes to health supplements. Through his work, Dr. Bryan aims to change our understanding of chronic disease prevention and management, advocating for a proactive approach to health focused on nitric oxide therapy. Key Takeaways: Nitric Oxide: Discover the importance of nitric oxide as a critical molecule for cardiovascular health, energy production, and inflammation reduction. Foundational Health: Understand how nitric oxide supports overall health, aging, and longevity, and the perils of its deficiency in chronic disease onset. Product Quality: Learn about the need for scientific backing in health products and Dr. Bryan's drive to provide nitric oxide therapies based on sound research. Proactive Health: The benefits of incorporating nitric oxide into daily routines, aiming to prevent health issues before they arise. Future Prospects: Hear about Dr. Bryan's vision for nitric oxide in medicine, including promising developments in therapies for heart disease and Alzheimer's. Resources: www.n1o1.com www.drnathansbryan.com IG: drnathansbryan FB: nathan.bryan.16 LI: drnathansbryan X: drnitric YouTube: @DrNathanSBryanNitricOxide ✨ Enjoying the show? Stay inspired long after the episode ends! Jana is gifting you free subscriptions to Ageless Living Magazine and Best Holistic Life Magazine—two of the fastest-growing publications dedicated to holistic health, personal growth, and living your most vibrant life. Inside, you'll find powerful stories, expert insights, and practical tools to help you thrive—mind, body, and soul.
Howdy guys! This episode was originally supposed to be about “betrayal trauma” but I got derailed by some very cool research and just had to discuss my THEORY on what mirror neurons and theory of mind (ToM) are for when it comes to sleep and wellness. I will absolutely be covering betrayal trauma next week so stay tuned, also I just finished the book on the neural mechanisms of reading and dyslexia so the episode two weeks from now will be jam packed with information on how to accommodate dyslexic readers and hopefully that'll be helpful on y'alls reading and learning journey! Thank you so much for joining me on this journey - I do apologize if it wasn't easy to follow, I truly didn't plan this one out so I will use more accessible language in the following episodes. I really did enjoy making this episode though, sharing information gives me such joy and I'm wishing everyone a happy National Autism Acceptance Month! Resources: Brain scans reveal how a woman voluntarily enters a psychedelic-like trance without drugs https://www.psypost.org/brain-scans-reveal-how-a-woman-voluntarily-enters-a-psychedelic-like-trance-without-drugs/ Manipulating light can induce psychedelic experiences — and scientists aren't quite sure why https://www.psypost.org/manipulating-light-can-induce-psychedelic-experiences-and-scientists-arent-quite-sure-why/ Scientists just found a hidden “drain” inside the human brain https://www.sciencedaily.com/releases/2026/04/260408225934.htm Scientists Finally Figured Out the Math Behind How You See Color https://www.popularmechanics.com/science/math/a70784732/color-theory-schrodinger/ 154 Visual Phenomena & Optical Illusions with Explanations by Michael Bach https://michaelbach.de/ot/index.html Dopamine GPS: Visual Guidance Beyond Reward https://neurosciencenews.com/dopamine-guidance-trajectory-30345/ Surprising study shows Alzheimer's may start in the body instead of the brain, a discovery that turns medical science upside down https://www.earth.com/news/genome-study-shows-alzheimers-may-start-in-body-tissue-inflammation-not-the-brain/ The influence of intentions on dream content https://academic.oup.com/sleepadvances/article/5/1/zpae088/7912101 Zeigarnik Effect https://www.psychologytoday.com/us/basics/zeigarnik-effect How Your Brain's Nightly Cleanse Keeps It Healthy https://www.scientificamerican.com/article/how-sleep-cleans-the-brain-and-keeps-you-healthy/ A shared code for perceiving and imagining objects in humans ventral temporal cortex https://www.science.org/doi/10.1126/science.adt8343 Behave: The Biology of Humans at Our Best and Worst - Robert M. Sapolsky For easy access to the information I'm referencing, see chapter 14 and 15. This Is What It Sounds Like: A Legendary Producer Turned Neuroscientist on Finding Yourself Through Music - Susan Rogers and Ogi Ogas I love this book in general but I got the information on James Turrell (the artist) from this book. For easy access the chapter is “Realism” An Elegant Defense: The Extraordinary New Science of The Immune System - Matt Richtel Apologies at 1:07:00 I said that the book I was reading was “Dreamscape” but it's actually Decisionscape by Elspeth Kirkman Learn more about your ad choices. Visit podcastchoices.com/adchoices
Dr. Moricz joins us from the Alzheimer's Treatment Centers of America. That's the place Tom is going. If you've been curious as to the methods and practices, now's your chance to sate that curiosity.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today, we chat with Dr. Emily Rogalski about the Healthy Aging & Alzheimer's Research Care Center, or HAARC, at the University of Chicago. She also provides a brief update about her SuperAging research. Show notes are available at www.NavNeuro.com/189 _________________ If you'd like to support the show, here are a few easy ways: 1) Get CE credits for listening to select episodes: www.NavNeuro.com/INS (for membership discount code, login to the-ins.org then go to this page: https://the-ins.org/current-members/special-offers-discounts/) 2) Leave an Apple Podcasts rating/review: www.NavNeuro.com/itunes 3) Check out our book Becoming a Neuropsychologist, and leave it an Amazon rating Thanks for listening, and join us next time as we continue to navigate the brain and behavior! [Note: This podcast and all linked content is intended for general educational purposes only and does not constitute the practice of psychology or any other professional healthcare advice and services. No professional relationship is formed between hosts and listeners. All content is to be used at listeners' own risk. Users should always seek appropriate medical and psychological care from their licensed healthcare provider.]
***JOIN THE NEXT MASTER YOUR FASTING CHALLENGE THAT STARTS April 22nd, 2026!*** We'll GUIDE you on how to FAST to LOSE FAT for good, and use ‘fast cycling' to achieve uncommon results! REGISTER HERE! Click the link for DATES, DETAILS, and FAQs! In this eye-opening episode, Dr. Scott Watier and Tommy Welling break down a promising randomized controlled trial exploring how a simple time-restricted eating window can meaningfully improve cognitive function in older adults with mild cognitive impairment — and what that means for everyone's long-term brain health. The hosts connect the dots between blood sugar regulation, insulin balance, and the growing body of research linking metabolic dysfunction to dementia and Alzheimer's, making a compelling case for why fasting is about far more than the number on the scale. They walk through the key mechanisms behind fasting's brain-protective effects — including circadian alignment, reduced neuroinflammation, improved insulin signaling, and the promotion of brain-derived neurotrophic factor — and why eating earlier in the day may be one of the most underrated levers anyone can pull. Listeners caring for aging loved ones will find practical, immediately actionable strategies for shifting meal timing and building a brain-supportive environment, even in small ways. The episode closes with a powerful reminder that building a consistent foundational fasting lifestyle today — anchored by protein, quality sleep, and earlier eating windows — is one of the most proactive investments anyone can make in their cognitive future. Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting! Resources and Downloads: SIGN UP FOR THE DROP OF THE ULTIMATE GUIDE TO BLOOD SUGAR CONTROL GRAB THE OPTIMAL RANGES FOR LAB WORK HERE! - NEW RESOURCE! FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS! SLEEP GUIDE DIRECT DOWNLOAD DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE! Partner Links: Get your FREE BOX OF LMNT hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase here! Get 25% off a Keto-Mojo blood glucose and ketone monitor (discount shown at checkout)! Click here! Our Community: Let's continue the conversation. Click the link below to JOIN the Fasting For Life Community, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them! Article Links: https://www.precisionnutrition.com/calories-in-calories-out
Most people think allergies are seasonal annoyances and autoimmune disease is just genetic bad luck. The science says otherwise and the doctor making that argument has spent her career tracing both epidemics back to a cascade of well-intentioned medical decisions made thirty years ago that got it catastrophically wrong. In this episode, I sit down with Dr. Tania Elliott, board-certified in internal medicine and allergy and immunology, to break down why your immune system is not broken, it is confused. We cover how chronic stress triggers the same physiological response as a bacterial invasion, why 80% of autoimmune diseases occur in women, and what is actually driving the 1 in 3 allergy epidemic. Dr. Elliott reveals the institutional failure behind the 2001 peanut guidance, why the 0.2% peanut allergy rate in Israel versus 10% in the US is not a coincidence, and why nut-free schools may be quietly creating the next wave of food allergies. We also get into what Benadryl is actually doing to your brain, why food sensitivity tests sold through influencers are close to useless, the real reason adults are suddenly developing shellfish allergies, and why the black plastic container your lunch arrived in is a serious problem. This episode will change how you think about your immune system, your child's early exposures, and the everyday decisions quietly shaping your long-term health. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: Why Your Immune System Is Not Broken, It Is Confused 01:02 Dr. Tania Elliott's Mission: Empowering People Through Evidence 02:46 What Is the Immune System and What Does It Actually Do 05:53 Autoimmune Disease, Chronic Stress, and Why 80% of Cases Are in Women 13:55 What Chronic Stress Actually Does to Your Immune System at a Cellular Level 25:29 The 1 in 3 Allergy Epidemic: What Changed in the Last 30 Years 30:08 The Hygiene Hypothesis, Antibiotics, C-Sections, and the Microbiome Disaster 36:09 The 2001 Institutional Failure That Made the Peanut Allergy Crisis Worse 41:52 Don't Put Peanut Butter on Your Child's Cheek, Do This Instead 43:19 Israel vs. the US: 0.2% vs. 10% Peanut Allergy and What Bamba Proved 45:37 Why Nut-Free Schools May Be Creating the Next Allergy Epidemic 49:29 Health Misinformation and the Algorithm's Role in Health Extremism 51:37 Developing Allergies as an Adult and the Shellfish Allergy Epidemic Explained 55:30 New Allergy Treatments, Useless Food Sensitivity Tests, and Black Plastic Containers 1:05:04 How to Spot Allergy Symptoms in Babies and Young Children 1:07:56 Why Benadryl Should Be Pulled From the Market _______ Thank you to our sponsors Daily Basis: https://www.dailybasislife.com/NEURO for 50% off first month Function Health: https://www.functionhealth.com/louisanicola Timeline: http://timeline.com/NEURO Jones Road Beauty: https://www.jonesroadbeauty.com and use code NEURO Lifeboost Coffee: https://lifeboostcoffee.com/ and use code NEURO for 10% off Just Thrive: https://justthrivehealth.com/NEURO _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
What actually causes cognitive decline, and how much of it can we do something about? In this episode, Michael talks with neurologist and neuroscientist Dr. Majid Fotuhi about dementia, Alzheimer's, memory loss, and the everyday habits that shape brain health over time. They discuss why Alzheimer's is only part of the story, why some people remain mentally sharp into old age, and what the evidence says about exercise, sleep, diet, stress, and cognitive activity. They also cover ADHD, attention, brain training, and the difference between ordinary forgetfulness and something more serious. At the center of it all is a simple but important idea: many people think cognitive decline is just an unavoidable part of aging, when in fact there is often more room to protect brain function than most of us realize. Majid Fotuhi, MD, PhD, is an adjunct professor of Neuroscience at Johns Hopkins's Mind/Brain Institute, an adjunct professor of Psychological and Brain Sciences at George Washington University, and is the medical director of NeuroGrow Brain Fitness Center. His groundbreaking, proprietary research has been published in The Lancet, Nature, Neurology, Neuron, Proceedings of National Academy of Science, the Journal of Prevention of Alzheimer's Disease, Journal of Rehabilitation, and Journal of Alzheimer's Disease Reports, among others. His new book is The Invincible Brain: The Clinically Proven Plan to Age-Proof Your Brain and Stay Sharp for Life.
Various Types of Dementia This week on PodcastDX, we're stepping into the complex world of dementia—not as a single diagnosis, but as a family of conditions that affect memory, thinking, behavior, and independence in different ways. We'll introduce the most common types of dementia, including Alzheimer's disease, vascular dementia, Lewy body dementia, frontotemporal dementia, and mixed dementia, where more than one process—often Alzheimer's plus vascular changes—are happening in the brain at the same time. We'll also touch on less common causes, such as dementia related to Parkinson's disease, normal pressure hydrocephalus, repeated head injury, and certain infections or genetic conditions, and talk about why getting the right type matters for treatment, planning, and support. Key Takeaways Dementia is an umbrella term, not just Alzheimer's. The "big five" you'll hear about are Alzheimer's, vascular, Lewy body, frontotemporal, and mixed dementia. Understanding the type of dementia can guide better care, expectations, and resources for families.
Intelligence Unshackled: a show for people with brains (a Brainjo Production)
A recent study published in Nature Medicine claims a blood test can predict when you'll develop Alzheimer's disease, and it got a lot of attention. But how well does it actually work, and should you rush out and get tested? In this episode, we break down the study behind the headlines to understand what it really shows, where the major limitations lie, and what it means for anyone thinking about getting this kind of test. Topics and Questions Covered What P-Tau 217 is and why it's become the leading blood-based biomarker in Alzheimer's research. How researchers built a predictive "clock" from blood test data and what that process required. The important distinction between having pathology in your brain and actually developing dementia. Who should and should not be getting tested. What a large Norwegian population study reveals about the overlap between pathology and normal cognitive function. How biomarkers like this might eventually fit into a broader, more personalized approach to prevention. and more! -------------- To submit a question for us to answer on the podcast, go to brainjo.academy/question. To subscribe to the free Better Brain Fitness newsletter, join us when we record live, and get our Guide and Checklist to essential blood tests and nutrients, go to: betterbrain.fitness. To learn more about how you can boost brain fitness with neuroscience-based musical instruction, head to brainjo.academy. Intro and Outro music composed and produced by Julienne Ellen.
AP's Lisa Dwyer reports on a charity auction of a Picasso painting in Paris. ((Watch for dating. Auction occurs 6 p.m. Paris time today))
AP correspondent Charles de Ledesma reports on the U.S. blockade of Iranian ports, and hopes for more ceasefire talks; Lebanon and Israel are set to negotiate in the U.S.; Pope Leo is retracing the steps of St. Augustine; and a raffle in France will sell a Picasso for $117, proceeds going to help Alzheimer sufferers.
El gobierno carga contra el juez Peinado tras el procesamiento de Begoña Gómez, la mujer del presidente, por cuatro delitos que incluyen tráfico de influencias y malversación, un hecho que la sitúa al borde del banquillo. La Moncloa y el PSOE critican la instrucción judicial y la tachan de "vergüenza". En el ámbito internacional, Donald Trump afirma que Irán busca diálogo, aunque Teherán lo niega y denuncia el bloqueo estadounidense, advirtiendo de posibles represalias en el mar Arábigo. Paralelamente, comienzan conversaciones entre Israel y Líbano para desmilitarizar a Hizbulá. El Papa León XIV defiende la paz, lo que provoca la crítica de Trump, quien lo considera "blando con el crimen". Además, la casa de subastas Christie's sortea un Picasso valorado en un millón de euros por cien euros, con el objetivo de recaudar fondos para la investigación del Alzheimer. Finalmente, un estudio neurocientífico revela que el reguetón activa más zonas del cerebro que la música clásica, ...
A equipe da neurocientista francesa Leslie Decker, da Universidade de Caen, no noroeste da França, desenvolveu um dispositivo que detecta sinais precoces de transtornos cognitivos e de doenças neurodegenerativas como Alzheimer e Parkinson. Lançado em 2019 no laboratório de realidade virtual da Universidade de Caen, o projeto Présage (Presságio, em tradução livre) é um programa acadêmico ambicioso que combina realidade virtual, matemática e inteligência artificial. Taíssa Stivanin, enviada especial da RFI a Caen O aparelho criado pelos cientistas franceses, parecido com uma esteira ergomética, foi instalado em uma sala de cerca de 15 metros de comprimento e nove metros de largura do CIREVE, o laboratório de realidade virtual da Universidade de Caen. Ele rastreia e registra riscos cognitivos e motores enquanto o paciente caminha e responde a perguntas que mobilizam atenção e memória. “Essa esteira permite avaliar o sistema locomotor e detectar biomarcadores que fornecem informações sobre o estado de saúde do participante. Tecnicamente, a esteira se adapta ao ritmo do paciente. Ela é equipada com duas plataformas de força, que registram o que chamamos de força de reação do solo, gerando dados sobre o equilíbrio dinâmico”, explica a neurocientista francesa. "A esteira também pode se inclinar na direção escolhida pelo participante e nas direções medial e lateral, mais complexas, que mobilizam mais recursos cognitivos para manter o equilíbrio. A esteira, claro, está conectada ao ambiente virtual”, explica. Durante o teste, o paciente é submetido a estímulos cognitivos enquanto caminha — primeiro em velocidade constante e depois em ritmos diferentes com cada perna. Ao mesmo tempo em que busca o ponto de equilíbrio deve executar simultaneamente uma outra tarefa: ler uma palavra em voz alta se ela estiver posicionada embaixo de um retângulo ou dizer qual é sua cor se for um losango. Em seguida, os pesquisadores franceses utilizam parâmetros matemáticos para avaliar e caracterizar os movimentos do paciente em função do risco cognitivo e motor. Quando detectado, ele triplica a probabilidade de desenvolvimento de transtornos neurocognitivos graves. “A ideia é saber se, nesse estágio bastante precoce, conseguimos identificar pacientes com risco de desenvolver esses transtornos”, afirma Leslie Decker. Dispositivo já foi testado em cem pacientes Cerca de cem pacientes, com idades entre 55 e 87 anos, já testaram a ferramenta e 20 deles apresentavam a chamada síndrome do risco cognitivo motor (MCR), caracterizada por lentidão da marcha e queixas cognitivas subjetivas. Para definir um perfil locomotor específico dessa síndrome, a equipe utilizou modelos de inteligência artificial e analisou dados de pacientes saudáveis, estabelecendo critérios de comparação, explica o pesquisador Baptiste Perthuy. “Isso permite identificar pacientes com risco de desenvolver doenças neurodegenerativas. A caminhada define um perfil locomotor, que é um reflexo do nosso estado estrutural. Isso é muito interessante porque traz muitas informações sobre uma patologia, uma pessoa e até mesmo sobre suas emoções”, diz. Segundo o cientista Julien Rossato, outro integrante da equipe, quando esses transtornos afetam os movimentos e as funções mentais, é possível medir no teste a chamada reserva cognitiva - a capacidade do cérebro de se adaptar ao envelhecimento. Ela pode diminuir com o surgimento de uma doença ou simplesmente se esgotar com o passar dos anos. “O que nos interessa particularmente é medir o desempenho nessas duas tarefas — caminhada e estímulos. Para isso, pontos semelhantes a eletrodos são conectados aos participantes e medem a posição no espaço, com ajuda de câmeras instaladas ao redor do sistema", explica. "Assim, temos acesso a variáveis como ângulos das articulações e o tempo que a pessoa leva para levantar a perna. Também avaliamos o desempenho cognitivo, registrando a voz do paciente e seu tempo de reação”, explica Rossato. A equipe utiliza modelos matemáticos e algoritmos avançados para analisar os dados e desenvolver estratégias de prevenção personalizadas. “A etapa final do projeto, depois de definido o perfil, é associar essas variáveis de desempenho a testes neurocognitivos ou questionários sociais”, afirma Julien Rossato. O dispositivo utilizado no laboratório da universidade está agora em fase de adaptação para uso em consultórios médicos. O sistema desenvolvido pela startup a-gO usa três iPhones para captar os movimentos do paciente enquanto ele caminha por cinco minutos em uma esteira. A partir desses vídeos, a inteligência artificial cria um modelo 3D detalhado da marcha e o analisa para identificar sinais da síndrome do risco cognitivo motor — condição que precede doenças neurodegenerativas e associa lentidão da marcha a queixas cognitivas, explica Alexandre Dalibot, um dos fundadores da empresa. O objetivo é traçar um perfil de pacientes com a síndrome ou com sinais que exijam atenção, possibilitando a adoção de medidas preventivas ou tratamentos mais personalizados. “A meta da a-GO era desenvolver uma ferramenta capaz de detectar precocemente pessoas com risco de desenvolver doenças neurodegenerativas. Nesse estágio, ainda temos todos os neurônios e a reserva cognitiva", diz. "Muitas medidas podem ser tomadas, e a ferramenta pode ser usada no dia a dia para monitorar a evolução desse risco. A ideia é adotar estratégias terapêuticas que permitam ao paciente agir e evitar transtornos associados ao envelhecimento. Vale lembrar que quase 75% das doenças neurodegenerativas podem ser evitadas”, afirma Dalibot. A ferramenta deve ser testada em breve em centenas de pacientes de hospitais franceses e pode chegar a consultórios médicos do país em até dois anos.
Sta je in de keuken en ben je vergeten wat je daar kwam doen? Geen paniek, dat is (waarschijnlijk) nog geen dementie! Maar wat is het dan wel? In aflevering WOW 357 duiken Istvan, Mario en Minya diep in het menselijk brein. Van de rol van je immuunsysteem (staan Alzheimer-genen eigenlijk wel in je hersenen?) tot de vreselijke 'gekko-koeienziekte' en het belang van vitamine B1. We bespreken de verschillende gezichten van dementie die vaak onderbelicht blijven.In deze aflevering:
Today's first hour features songs about storms, relationship conflicts, how the past intrudes into the present, the importance of community, unrequited love, losing a loved one to Alzheimer's, and more. The artists are from Melbourne, Ballarat, Daylesford, Gippsland, Fremantle and the USA. Here is the playlist: This Morning/U/The Rain – Sea Swallow Back to School – Alan Fletcher Whiskey Driven – Daisy Kilbourne Blue Water – The Milk Carton Kids Anything or Anyone – Romanie Room – Mike Reid & Joe Henry Beginnings – Chloe Violette Felicity (Demo) – Lewis Love Dance On – PepperCreek Revival ft. Kelly Auty You'd Gone Before You Went – Things of Stone and Wood Above: Chloe Violette's Colourfast album cover photo by Emily Dynes The post Beginnings – Show #385 (part 1), 29 March 2026 appeared first on Miss Chatelaine.
Most people think brain decline happens later in life.But what if the foods you eat every day are already shaping your memory, focus, mood, and long-term risk for dementia?In this episode of the Kwik Brain podcast, I'm sharing a powerful keynote from our Limitless Live event with Max Lugavere, health and science journalist, New York Times bestselling author, and one of the leading voices in brain health and dementia prevention.Max breaks down what the latest research shows about ultra-processed foods, protein, brain aging, and the everyday nutrition choices that either protect your brain or quietly work against it.He talks about why Alzheimer's prevention is not something we can ignore, how diet influences multiple modifiable risk factors for cognitive decline, and which foods support better memory, visual processing, blood flow, and long-term neurological resilience.In this episode, you'll learn:✅ Why ultra-processed foods may significantly increase Alzheimer's risk✅ How protein supports satiety, metabolic health, and long-term brain protection✅ Why red meat, eggs, and fatty fish may play a bigger role in cognitive health than most people realize✅ The effects of creatine and phosphatidylcholine on memory and brain performance✅ The foods that help protect both your brain and your vision✅ How to reduce inflammation, improve vascular health, and support dementia prevention✅ Why clean water, cleaner air, and a lower toxic burden matter more than most people thinkIf you want to protect your memory, think more clearly, and make smarter food choices for your future brain, this episode will help you understand what matters most and where to start.
Emma Heming Willis and Helen Christoni, co-founders of Make Time Wellness, join Dr. Will Cole to talk about a conversation that's long overdue: women's brain health. They cover the striking statistics around women and Alzheimer's risk, what brain fog and memory lapses are really telling us, and why the standard of care has been failing women for decades. From the Mediterranean diet and the 3,000-step rule to sleep hygiene and breathwork, Emma and Helen share the practical pillars of brain health - and the science behind why starting now, not later, is what matters most. For all links mentioned in this episode, visit www.drwillcole.com/podcast.Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors: Go to DRINKAG1.COM/WILLCOLE to get an AG1 Flavor Sampler and a bottle of Vitamin D3+K2 for FREE in your AG1 Welcome Kit with your first AG1 subscription order!Use code BEINGWELL at Monarch.com to get your first year half off at just $50.Head to moshlife.com/AOBW and subscribe today to get 25% OFF your first Variety Pack and 20% off your monthly subscription with code AOBW.You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/WILLCOLE and using code WILLCOLE at checkout.Refresh your wardrobe with Quince. Go to Quince.com/willcole for free shipping and 365-day returns. Now available in Canada, too.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode of the goodsugar Podcast, hosts Ralph Sutton and Marcus Antebi dive into one of the most fascinating and controversial questions in philosophy and neuroscience: do we actually have free will, or is everything predetermined?Broadcasting remotely from Miami, Marcus opens up about a deeply personal situation involving his father's battle with Alzheimer's, leading to an emotional and thought-provoking conversation about memory, identity, and how much control we truly have over our lives.From there, the discussion expands into a powerful debate on free will vs determinism, exploring ideas from leading thinkers like neuroscientist Robert Sapolsky and philosopher Noam Chomsky. The hosts break down concepts like:• How genetics, upbringing, and environment shape our decisions • The difference between micro choices and macro choices • Whether habits, anxiety, and emotional states limit our freedom • If personal transformation is proof that free will exists • The role of cause and effect in shaping our livesThis episode blends real-life experiences, humor, and deep philosophical insight, making complex ideas accessible and engaging. Whether you're into self-improvement, psychology, philosophy, or just great conversation, this is a must-listen.Do we control our destiny, or are we just along for the ride?See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Dr. Greg Cooper talks with Dr. Eric Reiman about emerging antibody therapies for preclinical Alzheimer disease and the clinical, regulatory, and equity considerations shaping prevention trials and future care. Read the related article in The Lancet Neurology. Disclosures can be found at Neurology.org.
Is it really possible to reduce your risk of getting dementia? Liz discusses the factors that contribute to developing it, and shares the diet and lifestyle changes we can make to protect the brain.Plus: dating after divorce, whether beef tallow is effective as a skincare product, tips to reduce injury when working out and HRT-free ways to manage menopause. In this episode:· Stepping back into the dating world after divorce· Applying beef tallow to your skin – fad or natural beauty hack?· Ways to manage menopause if you can't take HRT· Tips for reducing injury when working out in midlife Links mentioned in the episode:· Omega-3· Vitamin B [ES1] · Food for the brain website· Reduce your risk of Alzheimer's disease, with Patrick Holford· 10 ways to reduce your risk of Alzheimer's naturally· Information on homocysteine tests· NICE guidance· Podcast with Kirsty Lang and Dr Sarah Glynne on breast cancer and HRT· Protein· Creatine· Magnesium Get in touch with a question for Liz:· Email: podcast@lizearlewellbeing.com· WhatsApp: 07518 471 846More from Liz:· Preorder Liz's new book – How to Age· A Better Second Half· Follow Liz on Instagram· Follow Liz Earle Wellbeing on InstagramSome links may be affiliate links, which help support the show at no extra cost to you. Read our Affiliate Policy for more information. [ES1] Hosted on Acast. See acast.com/privacy for more information.
What if you could know 20 YEARS before symptoms appear whether you're heading for Alzheimer's? And what if there was a proven way to reverse early cognitive decline? In this episode, I sit down with my dear friend Dr. Dave Jenkins — the leading Dr. Dale Bredesen Protocol practitioner in the Southern Hemisphere — to unpack the p-Tau 217 blood test revolution and the stunning results from Bredesen's latest randomised controlled trial. Dr. Dave breaks down how a simple finger-prick blood test can now detect the Alzheimer's process with 95% certainty up to TWO DECADES before memory symptoms begin. This isn't diagnosing Alzheimer's — it's diagnosing the process, which means you have 20 years to intervene. We dive into Bredesen's 2024 multi-site RCT showing the ReCODE precision medicine protocol is 6–7x MORE POWERFUL than the best Alzheimer's drug currently available in America (lecanemab) — a drug with devastating side effects including brain bleeds and even death. Dr. Dave shares real clinical insights from his Bali longevity practice including the 30–60 "holes in the roof" driving cognitive decline, cutting-edge peptides (Semax, Selank, Cerebrolysin, Dihexa), bioregulators, and his personal experience with Klotho gene therapy that took his memory scores from the 70th to the 97th percentile in just 6 weeks. This is essential listening for anyone with a family history of Alzheimer's, anyone watching a loved one decline, and anyone who wants to take brain health seriously BEFORE it becomes a crisis. ⏰ CHAPTERS: [to be generated after edit]
Water covers roughly 70 per cent of the Earth's surface and is essential for human survival. But it can also unleash devastating consequences.In this week's episode, both of our storytellers share tales about water — from flooding to polluted groundwater. Through their stories, we explore how water shapes our cities, our safety, and our sense of security in a changing climate.Part 1: While researching flood risk and insurance costs in California, international student Hannah Melville-Rea is shocked by just how unprotected many people are. Part 2: Patricia Schuba is determined to stop coal and waste pollution from contaminating the groundwater in Labadie, Missouri. Hannah Melville-Rea is a PhD candidate and Knight-Hennessy Scholar at Stanford University, pursuing an interdisciplinary degree in Environment and Resources. Her research focuses on flood risk and examines how infrastructure decisions shape insurance costs and household vulnerability. She works closely with local agencies to translate research into practical tools that strengthen community flood resilience. Raised in Osaka, Japan by parents who hail from Australia and New Zealand, Hannah developed an early interest in how different countries tackle natural disasters. Today, she aspires to work at the intersection of science and policy to minimize the impact of climate hazards on frontline communities. Patricia Schuba has been active in organizing and politics since 2000. She founded two political organizations that worked to give voice to working Missourians living in rural areas, and she was a candidate for Missouri State House in 2018. She was a caregiver for her father with Alzheimer's who died in 2018, and she has had T1 autoimmune diabetes since childhood. She has been the president of all-volunteer Board of Directors of Labadie Environmental Organization (LEO) since 2011 and an active member since 2009. She has lobbied legislators, trained community members to find their voice, and led a citizens' movement in Missouri to end coal and waste pollution of our water and air. The pollution related work has been mostly from the heart and has forced her to grow in ways she never thought possible. It included learning media and advocacy skills but, more importantly… showed her how the world really works and how necessary citizens are in the process.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Have you ever parked your car, walked away, and completely blanked on where you left it? And yet… somehow you walked straight to it anyway? When that happens, it might not be luck. Rather, it could be your brain using what scientists now call “fuzzy memory.” And this might be the most important discovery about short-term memory in the last 20 years. To learn more, I sat down with Dr. Paul M. Garrett, currently doing postdoctoral work at the University of Melbourne. In addition to studying how your brain makes decisions when it’s uncertain, his recent article on The Conversation raised old and new questions related to how I think about forgetting, remembering, and every decision I make in between. Here’s one aspect of Paul’s research that blew my mind: The old theory said your brain has a fixed number of memory “slots.” If something made it into a slot, you remembered it. If it didn’t, it was gone. But that theory is apparently wrong. Rather, Paul’s research demonstrates that even memories you’d swear are completely gone still leave a faint signal in your brain, precise enough to push you toward the right answer without you even knowing why. That “gut feeling” you get sometimes? That might literally be a fuzzy memory talking. In this conversation we go deep on why your brain caps out at 3 to 4 items in working memory and what that actually means. https://www.youtube.com/watch?v=wm6C08m3WUI We also discuss why you remember better from a physical book than a screen (and the possible spatial memory scientific explanations behind it). Next, we discuss: How trained motor skills get so deep into procedural memory that even ten years away can’t break their strength How marketers and salespeople exploit your decision boundaries using time pressure Why a tiny dose of Bayesian reasoning would make almost everyone a sharper thinker What new EEG research on voluntary decisions reveals about whether or not free will is real How to make memory science more accessible by finding good science popularizers Paul and I had such a deep conversation that we kept going well past the formal interview. That bonus discussion covers experimental design for mnemonic research, Giordano Bruno‘s 16th century memory seals, the neuroscience of pitch detection and white matter volume, music therapy for Alzheimer’s patients, and a lot more on the topic of how memory works. You can access the full bonus conversation in the Magnetic Memory Method Masterclass. You’ll find it on the Bonus page. More About Paul Garrett & His Research To follow more from Paul, check out his: LinkedIn Profile Google Scholar page Profile on The Conversation If Fuzzy Memory Fascinated You, Go Deeper With These Science-Related Episodes Ready for more? Check out my conversations with: Dr. David Reser and Tyson Yunkaporta about Aboriginal Memory Techniques Dr. Gary Small on science-backed ways to keep memory strong Dr. Christine Till on research into brain training with apps Final Thought Here’s the final thing (for now) that comes to mind about fuzzy memory: If your brain is already doing this much work behind the scenes with zero memory improvement training, just imagine what it can do when you actually give it the right tools. That’s what the Magnetic Memory Method is built for, and that’s why it’s based around the Memory Palace technique. After all, many of us have been using locations we barely remember to memorize tons of information. So if you’re not familiar with this approach, or you’re worried that you can’t remember places you remember enough to use the method of loci, complete this Complete Guide to the Memory Palace technique. You might just be pleasantly surprised by just how much your fuzzy memories help you remember more than you ever imagined possible!
Dr. Marc Milstein is the author of the international best-selling book The Age-Proof Brain, nominated for the Next Big Idea Book Award and translated into seven languages worldwide. A leading brain health researcher and international keynote speaker, Dr. Milstein specializes in translating cutting-edge neuroscience into clear, actionable strategies to optimize brain health, lower the risk of dementia, and boost happiness and productivity. His insights have been featured by media outlets including CNBC, Oprah Daily, The New York Post, and Forbes. He has spoken for Fortune 500 companies and top associations worldwide, delivering dynamic, evidence-based keynotes that educate, entertain, and empower audiences.Dr. Milstein earned his Ph.D. in Biological Chemistry and a Bachelor of Science in Molecular, Cellular, and Developmental Biology from UCLA, where he conducted research in genetics, cancer biology, and neuroscience. His work has been published in multiple scientific journals.https://www.seniorcareauthority.com/resources/boomers-today/
AP correspondent Charles de Ledesma reports, there's excitement in Paris as a Picasso raffle will be held to help fund Alzheimer's research.
Alzheimer's disease unfolds over many years through a complex interplay of amyloid, tau, genetics, lipid biology, and the brain's immune response. John Hardy, Ph.D., explains how rare inherited forms of Alzheimer's disease helped shape current thinking about how the disease begins, then connects those discoveries to broader questions about late onset disease and why it develops differently across people. Hardy shows that amyloid and tau are linked but not identical, and argues that problems with protein buildup and clearance both matter in understanding the disease. He also emphasizes that Alzheimer's is not a single event but a long process, which makes prediction, diagnosis, and treatment especially difficult. While current amyloid-targeting therapies can help and show measurable benefit, Hardy says they do not stop the disease, underscoring the need for earlier diagnosis, better treatments, and wider access to care Series: "Shiley Endowed Lecture" [Health and Medicine] [Show ID: 41250]
Alzheimer's disease unfolds over many years through a complex interplay of amyloid, tau, genetics, lipid biology, and the brain's immune response. John Hardy, Ph.D., explains how rare inherited forms of Alzheimer's disease helped shape current thinking about how the disease begins, then connects those discoveries to broader questions about late onset disease and why it develops differently across people. Hardy shows that amyloid and tau are linked but not identical, and argues that problems with protein buildup and clearance both matter in understanding the disease. He also emphasizes that Alzheimer's is not a single event but a long process, which makes prediction, diagnosis, and treatment especially difficult. While current amyloid-targeting therapies can help and show measurable benefit, Hardy says they do not stop the disease, underscoring the need for earlier diagnosis, better treatments, and wider access to care Series: "Shiley Endowed Lecture" [Health and Medicine] [Show ID: 41250]
Alzheimer's disease unfolds over many years through a complex interplay of amyloid, tau, genetics, lipid biology, and the brain's immune response. John Hardy, Ph.D., explains how rare inherited forms of Alzheimer's disease helped shape current thinking about how the disease begins, then connects those discoveries to broader questions about late onset disease and why it develops differently across people. Hardy shows that amyloid and tau are linked but not identical, and argues that problems with protein buildup and clearance both matter in understanding the disease. He also emphasizes that Alzheimer's is not a single event but a long process, which makes prediction, diagnosis, and treatment especially difficult. While current amyloid-targeting therapies can help and show measurable benefit, Hardy says they do not stop the disease, underscoring the need for earlier diagnosis, better treatments, and wider access to care Series: "Shiley Endowed Lecture" [Health and Medicine] [Show ID: 41250]
Alzheimer's disease unfolds over many years through a complex interplay of amyloid, tau, genetics, lipid biology, and the brain's immune response. John Hardy, Ph.D., explains how rare inherited forms of Alzheimer's disease helped shape current thinking about how the disease begins, then connects those discoveries to broader questions about late onset disease and why it develops differently across people. Hardy shows that amyloid and tau are linked but not identical, and argues that problems with protein buildup and clearance both matter in understanding the disease. He also emphasizes that Alzheimer's is not a single event but a long process, which makes prediction, diagnosis, and treatment especially difficult. While current amyloid-targeting therapies can help and show measurable benefit, Hardy says they do not stop the disease, underscoring the need for earlier diagnosis, better treatments, and wider access to care Series: "Shiley Endowed Lecture" [Health and Medicine] [Show ID: 41250]
Today's episode is a MUST listen. This is one of the most important conversations you will ever hear about Alzheimer's prevention, dementia, memory loss, and brain health. If you're worried about your memory, your parents' memory, or your risk of cognitive decline as you age, this episode gives you something most conversations don't: real hope, backed by science, and a clear plan you can start today. In this powerful episode, Mel sits down with world‑renowned neurologists Dr. Ayesha Sherzai and Dr. Dean Sherzai, two of the leading medical experts in Alzheimer's disease, dementia, and cognitive decline. Together, they break down what dementia actually is, how Alzheimer's fits into it, and why brain decline often begins 20+ years before symptoms appear - long before most people think to pay attention to brain health. Dr. Ayesha and Dr. Dean explain how brain health is not determined by genetics alone, and why your daily habits have the power to prevent, slow, and even pause cognitive decline. They share the exact science‑backed framework they teach their patients, built around five simple pillars of brain health using one unforgettable acronym: NEURO. You'll also learn how to tell the difference between normal forgetfulness (like walking into a room and forgetting why) and early warning signs of dementia that should prompt a doctor visit. And if you're a caregiver - or love someone who is - this episode is essential listening. The doctors explain why caregivers face a significantly higher risk of cognitive decline, how chronic stress and poor sleep damage the brain, and what you can do to protect your own memory while caring for others. In this episode, you'll learn: - How to prevent Alzheimer's disease and slow cognitive decline using science‑backed daily habits - The difference between normal age‑related forgetfulness and early warning signs of dementia - What dementia actually is, how Alzheimer's fits into it, and why brain decline can start decades before symptoms - Why genetics are not your destiny when it comes to memory loss and brain health - The NEURO framework neurologists use to protect memory and reduce Alzheimer's risk - How exercise, deep sleep, stress reduction, and nutrition physically grow new brain connections There is so much good news in the research. There are simple, free things you can do starting today - even while listening - that can reduce dementia risk by up to 53% and dramatically improve long‑term brain health. If you're concerned about Alzheimer's, dementia, memory loss, or your cognitive future - this is the conversation you need. For more resources related to today's episode, click here for the podcast episode page. If you liked the episode, check out this one with neuroscientist, Dr. Wendy Suzuki next: Change Your Brain: #1 Neuroscientist's Exercise Protocol for Peak Energy and Focus Connect with Mel: Order Mel's new product, Pure Genius Protein Get Mel's newsletter, packed with tools, coaching, and inspiration. Get Mel's #1 bestselling book, The Let Them Theory Watch the episodes on YouTube Follow Mel on Instagram The Mel Robbins Podcast Instagram Mel's TikTok Subscribe to SiriusXM Podcasts+ to listen to new episodes ad-free Disclaimer Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Full Show Notes: bengreenfieldlife.com/magteinpodcast In this episode with neuroscientist Dr. Guosong Liu, you’ll explore his accidental discovery at MIT's Center for Learning and Memory that led him down a two-decade journey into brain magnesium, synaptic plasticity, and cognitive decline. That research ultimately resulted in the invention of Magtein® (magnesium L-threonate), a compound he engineered to cross the blood-brain barrier in a way other magnesium forms cannot, with clinical trials showing a reversal of nine years of cognitive decline, measurable shifts in sleep architecture, stress reduction in as little as three days, and meaningful improvements in prefrontal cortex function at just 140 milligrams per day. Dr. Liu also shares what his current Alzheimer's prevention research looks like. Dr. Liu is a world-renowned neuroscientist whose pioneering research on brain magnesium has transformed our understanding of cognitive function and synaptic plasticity. With more than 25 years of neuroscience expertise, he previously served on the faculty at MIT's Picower Institute for Learning and Memory, founded the Center for Learning and Memory at Tsinghua University, and earned his Ph.D. in Neurophysiology from UCLA. His translational research has bridged laboratory discovery and human clinical application, resulting in multiple trials demonstrating Magtein's efficacy in supporting cognitive performance. Magtein is the patented, clinically studied form of magnesium L-threonate designed to cross the blood-brain barrier and support memory, focus, mood, sleep quality, and stress resilience. Featured in more than 400 products across 40-plus countries, it is the global standard in brain-support magnesium nutrition. Ready to give your brain magnesium it can actually use? You can discover more about Magtein and find a brand that carries it here. Episode Sponsors: Quantum Upgrade: Recent research has revealed that the Quantum Upgrade was able to increase ATP production by a jaw-dropping 20–25% in human cells. Unlock a 15-day free trial with the code BEN15 at quantumupgrade.io. Troscriptions: Explore Troscriptions' revolutionary buccal troche delivery system that bypasses digestion to deliver pharmaceutical-grade, physician-formulated health optimization compounds directly through your cheek mucosa for faster onset and higher bioavailability than traditional supplements. Discover a completely new way to optimize your health at troscriptions.com/BEN or enter BEN at checkout for 10% off your first order. Fatty15: Fatty15 is on a mission to optimize your C15:0 levels and help you live healthier, longer. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/BEN and using code BEN at checkout. MTE: MTE is a caffeine-free daily drink mix with adaptogens, nootropics, and superfoods for clean energy, sharp focus, and balanced mood, without the crash. Boost your wellness at a systemic level with MTE's 13 healthy ingredients. Check them out at GetMTE.com/BENG and use code BENG for 20% off your first order.See omnystudio.com/listener for privacy information.
All Home Care Matters and our host, Lance A. Slatton were honored to welcome Denice Kennedy & Mike Weinberger the Founders of CaregivingCompanion.AI as guests to the show. In this heartfelt and forward‑thinking episode of All Home Care Matters, host Lance A. Slatton speaks with Denice Kennedy and Mike Weinberger, the co‑founders of CaregiverCompanion.ai — an innovative platform redefining how family caregivers and home care professionals manage care through smart technology. Denice and Mike share their passion for empowering caregivers to navigate the emotional and practical challenges of caring for loved ones with Alzheimer's and other age‑related conditions. Their groundbreaking AI solution helps families organize care tasks, improve communication, and find more time for what truly matters — compassionate connection. The discussion also features Mike Weinberger's powerful new book, "My Wife Has Alzheimer's, Now What?", a deeply personal account that offers guidance and hope to spouses and families walking the Alzheimer's journey. Through his experience, Mike sheds light on how love, resilience, and technology can work together to support caregivers everywhere.
Most people think astrology is a personality quiz. This conversation will make you reconsider that entirely. Naomi Nama Bracha is one of the most sought-after birth chart readers working today. In this episode, she sits down with me for a live, cold read of my chart pulling from the exact position of the sky at the time of my birth to reveal things I've never had explained to me before. Not in therapy. Not in any other conversation. We break down what a birth chart actually is, why it's more mathematical than mystical, and what the planets, signs, and houses each represent. We go into the Saturn-Neptune conjunction that just occurred an event that happens once every 320 years and what it means for the collective and for your chart right now. I also bring the science: a 2015 Columbia University study of 1.7 million patients found birth month correlates with risk for nine types of heart disease, and a 2023 meta-analysis confirmed that being born in winter or spring carries a 5 to 8% higher risk of developing schizophrenia. We also cover what astrology can do that therapy cannot, how synastry charts reveal the truth about your relationships, and how to access your own birth chart for free. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/brain-code Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Naomi Reads Louisa's Birth Chart Live 01:28 Planets, Signs, and Houses Explained 07:25 What Is a Birth Chart 13:48 Saturn on the Sun and the 10th House of Work 16:06 Why People Seek Astrologers and Saturn Returns 18:19 Pisces Rising: The Most Sensitive Sign 22:12 Your Rising Sign as Your Entry Point Into the World 23:36 The Science Linking Birth Month to Disease Risk 27:11 The Saturn-Neptune Conjunction and Current World Events 30:05 Pisces Season and What It Means Personally 33:55 How the Conjunction Is Rewriting Louisa's Identity 37:46 Can Your Chart Predict the Next 5 to 10 Years 39:32 Louisa's 2026 Reading and the Zodiac Life Cycle 42:11 The Shadow of Pisces: Over Giving and Numbing 45:11 Spiritual Practices, Solitude, and the Gym as Ritual 47:40 Freewill vs. Fate in Astrology 50:03 The New Generation and the New Collective Dream 51:56 What Astrology Does That Therapy Cannot 55:19 Synastry Charts and Relationship Patterns _______ Thank you to our sponsors Just Thrive: https://justthrivehealth.com/NEURO for 20% off Warby Parker: https://WarbyParker.com/NEURO Jones Road Beauty: https://www.jonesroadbeauty.com and use Code NEURO _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
At age 12, Dr. Chrystal Starbird stood by a pond after turning her mother in to the police. She watched tadpoles and fish move beneath the surface and found a strange kind of order. Science became her refuge long before it became her career. Years later, she built that refuge into a profession. She now serves as an Assistant Professor at the University of North Carolina, studies structural biology tied to cancer and Alzheimer's disease, and won Cell's first Rising Black Scientist Award in 2020. On paper, she fits the model of success. In practice, she had to fight for basic access at every stage.Conference travel required upfront cash she did not have. Networking favored pedigree over merit. Mentorship often depended on who knew your name in the room. Chrystal learned those rules, then chose to break them open for others.Oliver Bogler examines what Chrystal calls the advocacy tax. She has delivered over 70 invited talks. Nearly 40 percent focus on equity, mentorship, and policy. Academic reward systems do not count that labor toward tenure. She still does it.Through her leadership at the Life Science Editors Foundation, Chrystal helped build the JEDI program, which pairs underrepresented scientists with editors from journals like Cell and Nature. The program has supported over 100 awardees with more than 1,000 hours of mentorship. This episode exposes how biomedical science rewards output while ignoring the work required to make the system accessible. It also shows what happens when the people most affected refuse to step back.RELATED LINKSDr. Chrystal StarbirdStarbird LabLife Science Editors FoundationJEDI ProgramFEEDBACKLike this episode? Rate and review Out of Patients on your favorite podcast platform. For guest suggestions or sponsorship email podcasts@matthewzachary.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Hablar dos idiomas te hace mas inteligente y te aleja de Alzheimer!
HEALTH NEWS Natural alkaloid gramine suppresses triple-negative breast cancer by inducing ferroptosis Could vitamin D in midlife protect your brain from early Alzheimer's? Childhood Junk Food May Rewire the Brain for Life Swapping meat and dairy for plant-based foods cuts climate pollution by 35%, randomized clinical trial shows Exercise that trains brain and body helps managing ADHD-related difficulties Trailer for The Dangers of Vaccine Science - Purchase Your Tickets Now - https://garynull.substack.com/p/the-dangers-of-vaccine-science-trailer OR CALL 877-627-5065
In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr is joined by renowned neurologist and bestselling author Dr. David Perlmutter to explore one of the most important breakthroughs in brain health — the role of microglia. Often overlooked, microglial cells are the brain's immune system and play a central role in determining whether the brain thrives or degenerates over time. Dr. Perlmutter explains how these cells can shift between protective (M2) and destructive (M1) states — and how this shift underlies neurodegenerative diseases like Alzheimer's, Parkinson's, and more. Most importantly, this episode highlights how everyday lifestyle choices — from diet and exercise to metabolic health — directly influence brain function and long-term cognitive resilience. Join us as we delve into: What microglia are and why they control brain health The difference between M1 (destructive) and M2 (protective) states How metabolism shapes the brain's immune response Why conditions like Alzheimer's are rooted in immune dysfunction The connection between blood sugar, insulin, and brain degeneration This episode is for you if: You want to protect your brain and prevent cognitive decline You're interested in the science of Alzheimer's and neurodegeneration You want actionable strategies to improve brain health You're curious about the future of brain optimization and longevity You can also find this episode on… Youtube: https://youtu.be/EMrlchMOZKk Find more from Dr. David Perlmutter Website: https://www.drperlmutter.com Book: https://braindefenders.com LinkedIn: https://www.linkedin.com/in/david-perlmutter-md/ Instagram: https://www.instagram.com/davidperlmutter/ Facebook: https://www.facebook.com/DavidPerlmutterMd/ Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ Virtual Symposium 2026: https://homehope.org/homehope-virtual-symposium-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products
Send us Fan MailNicole Laurent is one the most featured returning guest on our show, so be sure to check out all her appearances on episodes 248, 343, 438, 538, and 744 of Boundless Body Radio!Nicole Laurent, LMHC, has been a licensed mental health counselor in Washington state for almost two decades. Her current practice focuses on helping her clients with anxiety, depression, and other mental health issues transition to a ketogenic diet or uses other nutritional therapies to complement their psychotherapy work.She holds several specialized training certifications, allowing her to work with underlying biological factors in mental illness. Nicole works with clients via telehealth, and helps people explore medication-free options for their mental health using research and evidence-based nutritional and functional psychiatry so that people can get their lives back without side effects or dependence on big pharma.In 2021, she created MentalHealthKeto.com, a blog devoted to educating people about ketogenic diets for mental health and neurological issues.Nicole is one of seven pioneers of Metabolic Psychiatry recognized by the Baszucki Brain Research Fund and the Milken Institute and has been given the Metabolic Mind Award in 2022Find Nicole at-https://mentalhealthketo.com/Study- Awareness and best practices in using ketogenic therapy to treat serious mental illness: a modified Delphi consensusIG- @mentalhealthketoTW- @KetoCounselorLK- Nicole Laurent, LMHCFB- @thatketocounselorFREE E-BOOK!Google Scholar link set with keyword "ketogenic"!Find Boundless Body at-myboundlessbody.comBook a session with us here!
Discover how WHOOP is building an AI-powered health data infrastructure that is redefining how we understand human health. Emily Capodilupo, Senior Vice President of Research, Algorithms, and Data at WHOOP, explains how continuous physiological data is uncovering new opportunities in predictive health through AI, from presymptomatic disease detection to biological age scoring. She examines the governance challenges of deploying AI in a regulated environment and what it takes to build the data trust required to make it work at scale. Key Moments: How WHOOP Built Its AI and Data Foundation (00:57): Emily explains how WHOOP's early focus on elite athlete performance shaped the data collection rigor and multidisciplinary science organization that now powers its predictive health capabilities. She outlines the model she built across AI, machine learning, clinical research, and digital signal processing, and why starting with the highest-demand use case created a data foundation built to scale. The Power of Continuous Data (06:21): Emily draws on WHOOP's sleep research to show how continuous physiological data reveals patterns that would be invisible without longitudinal tracking. She shares findings linking sleep architecture to metabolic disease, cancer risk, and cognitive decline, illustrating why the depth and continuity of a data set determine what insights are actually possible. The Data Governance Challenge of Acting on Sensitive Data (13:17): Emily shares how WHOOP's respiratory rate data could detect COVID infection up to three days before symptom onset in over 80% of cases, but a denied FDA application left the company holding actionable insights it was legally prohibited from sharing. She examines the governance tension that emerges when your data capabilities move faster than the regulatory frameworks designed to govern them. Turning Complex Multi-Signal Data Into a Single Actionable Metric (27:32): Emily introduces WHOOP's Healthspan feature, which translates physiological and behavioral data across nine components into a single biological age score tied to all-cause mortality risk. She explains why distilling complex data into one number is more motivating than presenting raw risk statistics, pointing to research that shows how age-based framing drives stronger behavior change. Building Data Trust and Privacy Infrastructure at Scale (31:40): As WHOOP moves into FDA-cleared products and more sensitive data collection, Emily outlines the governance principles that underpin member trust. She argues that for any organization building on sensitive personal data, the asymmetry between earning trust and losing it should be a foundational design constraint. Key Quotes: "It takes 13 years to earn the trust and one mistake to lose it. And that kind of asymmetry is constantly top of mind." - Emily Capodilupo "We were able to show that we could detect COVID up to three days before symptom onset in over 80% of cases." - Emily Capodilupo “ WHOOP has been collecting data [for] over 12 years. We're working on a lot of new types of algorithms that are able to help people understand their bodies in ways that we might not have appreciated…even just a couple years ago.” - Emily Capodilupo "One of the ways that AI has advanced the product... is this ability to chat with WHOOP in natural language, the way you might chat to a doctor or a trainer or a coach." - Emily Capodilupo Mentions Harvard Study | Analyzing changes in respiratory rate to predict the risk of COVID-19 infection Cornell Study Uses WHOOP Sleep Data to Monitor Patients at Risk for Alzheimer's Can Data Help Us Sleep Better? | WHOOP There's More to Sleep than Sleep Need: The Importance of Sleep Consistency | WHOOP Cribsheet & Expecting Better 2 Books Collection Set By Emily Oster The Family Firm: A Data-Driven Guide to Better Decision Making in the Early School Years By Emily Oster Guest Bio Emily Capodilupo is an award-winning AI and research leader with more than 13 years of experience building and scaling science-driven organizations in fast-paced startup environments. She began her career as an emergency medical technician before studying neurobiology and human sleep at Harvard University and conducting research at Brigham and Women's Hospital. Emily is driven by a passion for using data to solve hard problems and advance our understanding of human physiology. Along the way, she "accidentally" became a data scientist, recognizing that the biggest breakthroughs in health require not just rigorous science, but big data and bold technology. As WHOOP's first employee, Emily founded and now leads the company's science organization, pioneering a new model of health that begins long before diagnosable illness and is continuous, personalized, AI-powered, and designed to empower individuals to take the driver's seat in their own well-being. She has built and scaled multidisciplinary teams across artificial intelligence, machine learning, digital signal processing, clinical research, and engineering to translate real-time physiological data into actionable insights that improve performance, resilience, and long-term health. Emily's work sits at the intersection of wearable technology, digital biomarkers, and predictive health, helping shift healthcare from reactive treatment to proactive optimization. Hear more from Cindi Howson here. Sponsored by ThoughtSpot.
Sue Paul, an occupational therapist with more than 35 years of experience, joins AgingIN CEO Susan Ryan to share her journey reimagining dementia care through the lens of brain health. Reflecting on a time when Alzheimer's care was often institutional and limiting, Sue, who is senior director of well being and brain health for Asbury Communities, developed a more proactive, person-centered framework focused on prevention, dignity, and understanding the trajectory of cognitive change. Her work has evolved into a strong emphasis on lifestyle-based interventions—movement, cognitive engagement, stress management, and social connection—as powerful tools to support and even improve brain health. At Asbury, Sue brought this philosophy to life through the Rosborough Wellness and Brain Health Center, an innovative space featuring everything from a rock-climbing wall to a boxing studio and tech lab, all designed to make brain health visible, engaging, and stigma-free for more than 380 residents. Central to her approach is the Kinnections program with compelling results showing that 90 percent of participants maintaining or improving cognitive function and half of those with mild cognitive impairment returning to normal cognition. Sue is also leading a shift in language and mindset, encouraging providers to move away from "memory care" toward a more holistic concept of "neuro health." Beyond campus walls, Sue is expanding her impact through SeniorScapes, a dementia-friendly park model in Frederick, Md., designed to promote outdoor activity, cognitive engagement, and social connection.
If you carry the ApoE4 gene, you've likely been told your risk for Alzheimer's disease is significantly higher. But what does that really mean, and how much control do you actually have?In this video, Dr. Bret Scher breaks down the science behind ApoE4, one of the strongest genetic risk factors for Alzheimer's disease, and explains why increased risk does not mean a predetermined outcome.You'll learn how ApoE4 may influence brain health through inflammation, lipid metabolism, and energy use, and why lifestyle and environment play a critical role in shaping these pathways.This video also explores:Why ApoE4 does not guarantee Alzheimer's diseaseWhat research shows about traditional populations with low dementia ratesHow metabolic health, diet, and lifestyle may influence brain agingNew research challenging common assumptions about meat, fat, and dementia riskThe role of key nutrients like B12, iron, and amino acids in brain functionDr. Scher also reviews recent observational studies suggesting that higher meat consumption may be associated with lower dementia risk in ApoE4 carriers, challenging long-standing dietary narratives.The takeaway: your genes are one piece of the puzzle. Your daily choices, environment, and metabolic health may play a powerful role in shaping long-term brain outcomes.
This week, Penn and I share some real-life updates from our house. I was recently diagnosed with ADHD at 50, which turns out… there were signs. I'm learning what that actually means for my brain, my emotions, and honestly, my entire life up to this point. (Something called “doom piles” should have honestly exposed my ADHD years ago.)Penn also shares an update on his journey to protect his brain health from Alzheimer's. We talk about what he's trying, what we're learning, and how we're thinking about the future. He has two copies of the APOE4 gene and has watched both of his parents succumb to the disease. To be clear, I would do witchcraft if it meant he will remember my name when we're both in the retirement home. We bring back What Gen Zers Are Saying, Penn Compliments Men (shout out to Dan!), and a very relatable story on the Laugh Line about a deer, a college kid, and a callback. Thanks for laughing along with us. We love to hear from you! Leave us a message at 323-364-3929 or write the show at podcast@theholdernessfamily.com. You can also watch our podcast on YouTube.Learn more about our new kids book!Hear Dan's viral song parody!Visit Our ShopJoin Our NewsletterFind us on SubstackFollow us on InstagramFollow us on TikTokFollow us on FacebookLaugh Lines with Kim & Penn Holderness is an evolution of The Holderness Family Podcast, which began in 2018. Kim and Penn Holderness are award-winning online content creators known for their original music, song parodies, comedy sketches, and weekly podcasts. Their videos have resulted in over three billion views and over nine million followers since 2013. Penn and Kim are also authors of the New York Times Bestselling Books, ADHD Is Awesome: A Guide To (Mostly) Thriving With ADHD and All You Can Be With ADHD. They were also winners on The Amazing Race (Season 33) on CBS. Laugh Lines is hosted and executive produced by Kim Holderness and Penn Holderness, with original music by Penn Holderness. Laugh Lines is also written and produced by Ann Marie Taepke, and edited and produced by Sam Allen. It is hosted by Acast. Thanks for listening! Hosted on Acast. See acast.com/privacy for more information.
Most people think going to the gym for aesthetics is shallow. Science says it's actually the most honest starting point you've got and the person making that argument built one of the most respected evidence-based fitness companies in the world, openly used steroids, and then had surgery to remove his love handles. In this episode, I sit down with Dr. Mike Israetel, PhD in Sport Physiology and co-founder of Renaissance Periodization. We break down why two 20 minute workouts a week can build genuine muscle, why compound movements beat isolation exercises for nearly everyone, and why yoga and Pilates will not get you the physique you're after. Mike also opens up about his own use of anabolic steroids and cosmetic surgery, and makes the case that aesthetics pursued honestly and without shame is one of the most empowering conversations in health. Then we go deep on the future of the human body: GLP-1s, myostatin inhibitors, retatrutide, and why Mike believes that by the 2040s, no disease we can identify today will still exist. We also cover AI-driven medicine, recursive self-improvement, the brain rot epidemic, and what's inside his upcoming book The Aesthetics Revolution. This conversation will completely change how you think about why you train, how you train, and what the human body is about to become. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The Biggest Mistake Most People Make With Their Training 05:17 The 20-Minute Paired Exercise Program That Hits Every Muscle Group 22:34 Will Lifting Make Women Bulky? Debunking the Biggest Fear 30:24 Why Women Train Too Light and How to Fix It 35:05 Mike's Origin Story: 20 Years, RP, and Fighting Fitness Misinformation 37:28 Yoga, Pilates, and Why They Won't Give You the Physique You Want 47:18 Mike's Cosmetic Surgery: Removing Love Handles, Zero Regrets 53:11 The Aesthetics Revolution Book and the Future of Looking How You Want 59:38 GLP-1s: What Nobody Tells You 01:07:18 AI and the End of Disease: Why Mike Thinks the 2040s Changes Everything 01:16:25 Brain Rot, Literacy, and the Cognitive Cost of the Scroll Era 01:23:15 Personal AI as Life Coach: What's Coming by 2027 _______ Thank you to our sponsors KetoneIQ: https://ketone.com/NEURO for 30% OFF Kion: https://getkion.com/neuro for 20% off Pulsetto: https://pulsetto.tech/pages/NEURO or use Code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices
Casey Stumpf is a nurse practitioner with 18 years of clinical experience spanning emergency medicine, military family health at Camp Pendleton, hospice care, and hormonal optimization. She holds a Menopause Society Certified Provider credential and a bachelor's in dietetics from UC Davis. She now runs a practice in California focused exclusively on perimenopause, menopause, and hormonal health for both men and women. In 2002, a study got published before the researchers finished reviewing it. The media ran with one conclusion: estrogen causes cancer. For the next two decades, women were stripped of hormone therapy and told to white knuckle through the worst years of their lives. That same study actually showed women on estrogen alone had 18% less breast cancer. Nobody reported that part. Casey walks through exactly what happened, why the data was misread, and what six decades of fear have cost 75 million American women — only 5% of whom are on hormones today. We get into the real mechanics of what perimenopause does to the brain and body, why testosterone is her favorite hormone for women, the connection between untreated menopause and Alzheimer's, hip fractures, heart disease, and divorce. She talks about sitting bedside through hundreds of hospice deaths and how that shaped everything she does now. We talk about our mom's end-of-life letter, our dad's refusal to age gracefully, and what it means to build your 80-year-old self in midlife. https://theradiantwelltality.com/ Today's Sponsors: Montana Knife Company: https://www.montanaknifecompany.com Brunt: For a limited time, our listeners get $10 off at BRUNT when you use code "clearedhot" at checkout. Just head to https://www.bruntworkwear.com
Alzheimer's doesn't start when symptoms show up—it starts decades earlier.In this episode, Max Lugavere breaks down how everyday habits are either protecting your brain… or slowly working against it. From body fat and muscle to sleep, diet, and activity levels, the biggest risk factors are often the most common behaviors.Special perks for our listeners below!
Your home could be quietly stealing your IQ, disrupting your hormones, destroying your mitochondria, and triggering chronic disease, and most people never connect the dots. This episode gives you the full picture on toxic mold, and exactly what to do about it Learn More About The Superstratum Products Dave Uses At: https://superstratumlabs.com/products/dave Host Dave Asprey sits down with Seth Jones, CEO of Superstratum and the creator of the first patent-pending process to remove mycotoxins from homes. Before founding Superstratum, Seth spent 15 years as an international songwriter, producer, and DJ until a personal experience with Building-Related Illness changed the entire direction of his life. Today he and his team are on a mission to heal the estimated 66 million homes in the U.S. that create toxic conditions for the 170 million people living inside them. If toxic mold has derailed your health, your relationships, or your ability to think clearly, this conversation will change how you see your home forever. Dave Asprey built his entire biohacking and longevity career trying to fix what mold did to his body. By his mid-twenties, he carried diagnoses of arthritis, chronic fatigue, fibromyalgia, and mold-induced brain damage that wiped out his prefrontal cortex activity. Functional medicine doctors couldn't help him. Specialists gave up. It took him years of self-directed research into mitochondria, metabolism, and environmental toxicology to understand that his home was the root cause. He lost 100 pounds, reversed brain damage confirmed by imaging, and recovered IQ points he thought were gone for good. In this episode, Dave and Seth break down the real science of how mycotoxins poison mitochondria, hijack hormones, crush sleep optimization, and block the neuroplasticity your brain needs to perform. They reveal why mold is additive with every other toxin in your environment, why most remediation fails, and how a systematic home detox protocol can do what no supplement, nootropic, or fasting protocol can fix on its own. You'll Learn: Why mold toxins are direct mitochondrial poisons and what that means for your energy, willpower, and metabolism How mycotoxins lower your IQ by up to 15 points and why removing them reverses the damage The estrogen-mimicking mold toxin 10,000 times stronger than human estrogen that causes weight gain no diet can fix Why your AC and HVAC system are the most dangerous mold delivery systems in your home How mold disables detox pathways and makes every other environmental toxin worse The connection between toxic mold, Lyme disease, Alzheimer's, cancer, and fertility loss Why Danger Coffee and mold-free nutrition matter as much as fixing your home The step-by-step Superstratum protocol for fogging, bombing, coating, and restoring a healthy home microbiome How to salvage your belongings, treat your car, and avoid recontaminating a clean environment Thank you to our sponsors! - Suppgrade Labs | Grab your DAKE and Minerals 101 duo at shopsuppgradelabs.com and use code DAVEPOD for 15% off today - Superstratum Labs | Get Dave's exact home mold detox kit and save 10% at superstratumlabs.com/products/dave Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Seth Jones, Superstratum, toxic mold symptoms, mycotoxins in homes, Building-Related Illness, mold and IQ, mold brain damage, HVAC mold, home detox protocol, hypochlorous acid mold, environmental probiotics, HomeBiotic, mold and mitochondria, mold and hormones, zearalenone estrogen, mold weight gain, mold and fertility, mold and Alzheimer's, mold and Lyme disease, ochratoxin, mold and chronic fatigue, Dave Asprey, biohacking, longevity, functional medicine, human performance, anti-aging, Danger Coffee, mold detox, brain optimization, sleep optimization Resources: • Learn More About The Superstratum Products Dave Uses At: https://superstratumlabs.com/products/dave • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:46 – Intro 01:27 – Dave's Mold Origin Story 02:37 – Health Decline & Recovery 06:02 – Coffee, Bulletproof & Moldy Movie 10:17 – Systemic Effects of Mold 13:24 – Introducing SuperStratum 18:04 – Weight, Hormones & Brain Damage 19:53 – Brain Scans, Sleep & Symptoms 26:09 – Fertility, Prevention & Costs 31:03 – Treating the Home 42:42 – Seth's Story 48:45 – Resources & Car Detox See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.