Podcasts about Immunology

Dr. Shuvro Roy and Dr. Daniel Blockmans discuss the efficacy and safety of upadacitinib as a treatment option for giant-cell arteritis.  Show reference:  https://www.nejm.org/doi/10.1056/NEJMoa2413449 

Show Notes:Summary In this episode, Victoria Menendez interviews Ivanna Marroquin about her experiences in veterinary school as she approaches the end of her first year. They discuss the challenges of finals, study habits, personal care, and future plans for the summer, including a teaching assistant position and a trip to visit family. Ivanna shares her insights on managing stress, maintaining well-being, and preparing for the next academic year.Keywords VetaHumanz, veterinary school, finals, study habits, personal care, summer plans, veterinary medicine, student life, academic challenges, mental health, veterinary educationTakeawaysIvanna is nearing the end of her first year in veterinary school.Finals are approaching, and she feels a mix of stress and excitement.Immunology and physiology are her biggest academic challenges this semester.She is adapting her study habits, including using Anki for spaced repetition.Personal care is important, but sleep has been sacrificed during finals.Ivanna took a break by going to the movies, which helped her recharge.She plans to be a TA for a summer program that helps undergraduates prepare for vet school.The summer program offers insights into veterinary education and clinical experience.Ivanna is excited to visit her grandpa in Florida after the semester ends.She aims to return to her second year with confidence and a solid understanding of the material. Chapters00:00    Journey Through Veterinary School04:13    Facing Challenges and Study Strategies09:14    Balancing Personal Care and Academics12:29    Future Aspirations and Summer Plans

The Immune team goes up the nose to discuss cytotoxic T cells activating complement through secretion of granzyme K to drive inflammatory nasal polyps and how IgA-producing B cells are made in the nose. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server CD8 T cells in recurrent airway inflammation (Nature 2025) Where IgA producing B cells arise that protect the nose (Nature 2024) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.  

ReferencesRedox Biology 2021. Volume 47, November 102165J Biol Chem. 2005 Dec 2;280(48):40012-24.Ann Transl Med.2021 Jan;9(2):154.J Clin Lab Anal. 2021 Dec 3;36(1):e24163Guerra, DJ. 2025 Unpublished LecturesCrosby, D, and JA. 1970. "Have you seen the Stars tonight?"From Blows Against the Empire" lp Jefferson Airplane /Starshiphttps://music.youtube.com/watch?v=URctL2Br7Rc&si=LDbV_yEG6MOmVZyZKubrick/Clarke. 1968. 2001 A Space Odessey.https://music.youtube.com/watch?v=oALxLNOhI6I&si=JuE8cxLfvD8v3Up7

Dr. Shuvro Roy talks with Dr. Daniel Blockmans about the efficacy and safety of upadasatinib as a treatment option for giant-cell arteritis.  Read the related article in The New England Journal of Medicine.  Disclosures can be found at Neurology.org. 

In today's OncClub episode, we had the pleasure of speaking with Branden Moriarity, PhD; and Beau Webber, PhD, about a study evaluating neoantigen-reactive CISH knockout tumor-infiltrating lymphocyte (TIL) therapy in patients with metastatic gastrointestinal cancers. Dr Moriarity is an associate professor in the Division of Pediatric Hematology/Oncology, co-director of the Center for Genome Engineering and the Genome Engineering Shared Resource (GESR), and a member of the Center for Genome Engineering at the University of Minnesota in Minneapolis, where he is also a faculty member in the Department of Pediatrics; the Microbiology, Immunology and Cancer Biology (MICaB) PhD Graduate Program; the PhD Program in Molecular, Cellular, Developmental Biology and Genetics; the Cellular and Molecular Biology (CMB) Graduate Program, and the Masters Program in Stem Cell Biology. He is also a member of the Stem Cell Institute at the Masonic Cancer Center. Dr Webber is an associate professor in the Division of Pediatric Hematology/Oncology, co-director of the GESR, and a member of the Stem Cell Institute at the University of Minnesota Medical School, where he is also a faculty member in the Department of Pediatrics, the Molecular Pharmacology & Therapeutics Graduate Program, and the Masters Program in Stem Cell Biology. He is also a member of the Masonic Cancer Center. In our exclusive interview, Drs Moriarity and Webber discussed how targeting the CISH gene using CRISPR enhances T-cell function, key safety and efficacy findings from this study in 12 patients, and future research efforts that may focus on reducing manufacturing time and cost, as well as enhancing T-cell resilience. Check out the full OncClub subseries to see additional findings and insights from this research!

ReferencesInt J Mol Sci. 2020 Sep 22;21(18):6973.Cells. 2019 Mar; 8(3): 227.J Diabetes Complications. 2022 Oct 5;36(11):108333. Guerra, DJ. 2025. Lectures unpublishedCetera, P. 1969. "Liberation" Chicago Transit Authority lp.https://music.youtube.com/watch?v=4EPGCZ-eBSs&si=ICPGcKon4Ez4SAa-Beethoven, LV. 1802. Piano Concerto V. in E Flat Major. "The Emperor" OP 73.https://music.youtube.com/watch?v=WxMLHBZ4vOE&si=uBflUVY9uQB7vl5u

ReferencesGuerra, DJ. 2025. Unpublished lecturesNature Reviews Molecular Cell Biology 2023. volume 24, pages 86–106 Nature Communications2022. volume 13, Article number: 139 Redox Biology 2018. Volume 15, May. Pages 1-11Redox Biol. 2022 Feb 4;50:102257Int J Mol Med. 2015 May;35(5):1290-300Hunter/Garcia 1972. "He's Gone" Europe 72' lp.https://music.youtube.com/watch?v=gFqNGWZrlh8&si=Yl_cGspMtj3oF66tSlick, G. 1968. "Lather" Jefferson Airplane https://music.youtube.com/watch?v=3VYDBZzM-g0&si=xHjRPaTIThKof7MlBetts, D. 1970. "In Memory of Elizabeth Reed." Allman Bros Band Live at the Fillmore.https://music.youtube.com/watch?v=8jVz1NSZIlo&si=2qrsQQ5PVHNuGRpPBeethoven, LV 1811. Symphony 7 in A Major. op.92https://music.youtube.com/watch?v=Rd0HnxWm5CY&si=SP45yi5t2AT9XhM3

ReferencesFront Immunol. 2021; 12: 613591Guerra, DJ. Unpublished lecturesSchubert, F. 1826 (summertime). Symphony in C Major D.944.(9th/8th) "The Great"https://youtu.be/dVDQsWMApCU?si=iF8vt07I1XMBDr0_Hayward, J. 1967. "Nights in White Satin" Days of Future Passed lphttps://music.youtube.com/watch?v=4B5WHQMNm4I&si=05a_Bs1smfm3-e1h

ReferencesProtein Cell. 2021 Apr; 12(4): 240–260. Journal of Experimental & Clinical Cancer Research 2022 volume 41, Article number: 303 Nestor/Armatrading 1975 "Visionary Mountains" MMEB Nightingales&Bombers lp.https://music.youtube.com/watch?v=Y_u_GyHgOW0&si=v8dUjpN4RE9ljWJW

We should all go to a 4 day week! Science strongly supports the Four-day work week, benefiting workers and employees Professor Luke O'Neill Professor of Immunology at Trinity College Dublin tells us all.

Send us a textIn this episode, David McCulley and Betsy Crouch interview Dr. Benjamin Fensterheim, a neonatology physician scientist, who shares his journey through medical training, the inspiration behind his immunology research, and the importance of bridging the gap between basic science and clinical neonatology. The conversation delves into the challenges faced by physician scientists, the evolving landscape of neonatal care, and the need for innovative therapies in the NICU. Dr. Fensterheim emphasizes the significance of community and mentorship in supporting early-career researchers and advocates for the value of science in improving healthcare outcomes for infants.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Synopsis: Host Rahul Chaturvedi sits down with Jeremy Bender, CEO of Day One Biopharmaceuticals, to explore the bold mission of transforming pediatric oncology. From earning FDA approval for a groundbreaking brain cancer drug to building a culture rooted in execution and empathy, Jeremy shares lessons from big pharma and startups alike. He discusses how to lead through uncertainty, scale with discipline, and stay focused on delivering targeted therapies for underserved patients. They also dive into real-world data, AI's emerging role in clinical trial design, and why pediatric-first innovation could reshape the future of oncology. Biography: Jeremy Bender, Ph.D., M.B.A. has served as our Chief Executive Officer, President and a member of our board of directors since September 2020. Prior to joining Day One, Dr. Bender was Vice President of Corporate Development at Gilead Sciences, a pharmaceutical company, from March 2018 to September 2020. Prior to that, he was Chief Operating Officer of Tizona Therapeutics from July 2015 to March 2018 and Chief Business Officer of Sutro Biopharma, a biotechnology company specializing in cancer and autoimmune therapeutics, from October 2012 to July 2015. Prior to joining Sutro Biopharma, he was Vice President of Corporate Development at Allos Therapeutics, a biotechnology company focused on cancer treatments, from January 2006 to September 2012. Dr. Bender also sits on the board of Mereo BioPharma as an independent board member. He started his career in the life sciences practice at Boston Consulting Group, a management consulting company. Dr. Bender holds a B.S. in Biological Sciences from Stanford University, a Ph.D. in Microbiology and Immunology from the University of Colorado, and an M.B.A. from the MIT Sloan School of Management.

When you imagine a scientific conference, you may picture rows of poster boards, bustling coffee breaks, and seasoned researchers discussing the latest data and research approaches. It can feel like a world reserved for insiders. Yet a recent study led by Dr Malgorzata Trela and Dr Sophie Rutschmann at Imperial College London argues that this lively professional gathering is precisely where tomorrow's scientists ought to cut their teeth. Their paper, “Immunology in Practice: a modular framework to support Master of Science students' conference attendance and engagement,” describes an educational project that turns a four-day professional congress into the beating heart of a master's-level module, and in doing so, reshapes how students learn, network and even see themselves.

What happens when 3,500 staffers lose their jobs due to FDA layoffs, venture capital (VC) term sheets shrink, and AI drug-discovery startups raise $600 million rounds? Executive recruiter William Holodnak (ex-Fidelity, global biotech headhunter) breaks down 2025's wild hiring market—and how founders can still build A-teams.In this episode you'll learn:- Why the April-1 FDA layoffs could delay approvals—and open new career doors for ex-regulators. - The three traits VCs demand in first-time biotech CEOs during a funding slump. - How AI-driven platforms like Isomorphic Labs raised mega-rounds in a down market. - Immunology's surge and why oncology startups are pivoting. - Board-level recruiting tactics that de-risk your Series B.

Fungi gave us penicillin, a hugely beneficial antibiotic that has saved millions of lives. Cholesterol lowering statins had their origins in fungi, as did the immunosuppressant cyclosporin used in transplantation. These results show that many more medicines derived from fungi remain to be found. All to discuss with Professor Luke O'Neill Professor of Immunology at Trinity College Dublin.

Welcome back to Ditch the Lab Coat, the podcast where we break down the fascinating world of medicine with a blend of scientific skepticism and real-world insight. In today's episode, we dive deep into the mysteries of the vagus nerve—a nerve so ancient and essential, it's been called the “conductor” in the symphony of human physiology.Join host Dr. Mark Bonta as he sits down with Dr. Kevin Tracey, neurosurgeon, president and CEO of the Feinstein Institutes for Medical Research, and a pioneer in the world of bioelectronic medicine. Dr. Tracey's breakthrough research has shown us that the vagus nerve is far more than just a conduit for signals—it's a key player in managing inflammation, regulating our immune system, and maybe even shaping the future of medicine.In this conversation, you'll explore the mind-bending complexity of the nervous system, discover how cutting-edge science is redefining how we treat diseases like rheumatoid arthritis and long Covid, and learn how a tiny chip implanted in the neck might one day replace whole classes of immune-suppressing drugs. Dr. Tracey shares metaphors, straight talk about medical myths, and a vision for a future where reprogramming the body's reflexes could offer relief to millions.Get ready for a journey that's equal parts awe-inspiring and practical, as we unpack the true potential (and real-world considerations) of harnessing the vagus nerve's power. Whether you're a healthcare professional, a science nerd, or just someone searching for new answers, this episode invites you to see medicine in a whole new way. Resources : ( https://feinstein.northwell.edu/ )Episode HighlightsVagus Nerve Complexity Unveiled — We're only scratching the surface of understanding the vagus nerve's vast, intricate network and its essential bodily roles.Inflammation: Friend and Foe — Inflammation is vital short-term, but when uncontrolled, it's destructive and underlies many autoimmune and chronic diseases.Nervous-Immune System Interplay — The nervous and immune systems communicate reflexively, with nerves directly capable of controlling immune and inflammatory responses.Bioelectronic Treatments Emerge — Vagus nerve stimulation—via implanted chips—shows promise for conditions like rheumatoid arthritis without full-body immunosuppression risks.Individualized Nerve Fiber Functions — Each of the 200,000 vagus fibers controls specific functions, forming a body-wide symphony of precision responses.Not All Self-Help Fits — Lifestyle hacks can support vagus health, but serious disease often requires targeted nerve stimulation, not general wellness.Caution Against Online Misinformation — Vagus nerve advice online is often oversimplified or inaccurate; nuance and scientific backing are essential.Lifestyle Still Matters — Balanced diet, sleep, exercise, and community all help regulate vagus nerve tone and reduce chronic stress.Future Disease Applications Possible — Vagus stimulation may treat IBD, MS, and neurodegenerative or psychiatric conditions as research evolves.Episode Timestamps6:25 — Exploring Nervous System Complexity9:08 — Vagus Nerve Controls Inflammation11:05 — Vagus Nerve: Brain Signals Control Inflammation15:45 — Nervous System's Role in Immunity20:43 — Understanding Your Vagus Nerves23:25 — Vagus Nerve Health and Research25:12 — Vagus Nerve Stimulation Insights29:36 — Vagus Nerve Stimulator: Inflammation Therapy32:13 — Neurotransmitter Effects on Cytokine Production38:22 — Minimizing Nerve Damage in Surgery39:30 — Vagus Nerve Stimulation Benefits43:42 — Exploring Vagus Nerve Mysteries46:42 — Vagus Nerve Stimulation for Autoimmune Diseases50:52 — Cold Plunges & Bioelectrical Future DISCLAMER >>>>>>    The Ditch Lab Coat podcast serves solely for general informational purposes and does not serve as a substitute for professional medical services such as medicine or nursing. It does not establish a doctor/patient relationship, and the use of information from the podcast or linked materials is at the user's own risk. The content does not aim to replace professional medical advice, diagnosis, or treatment, and users should promptly seek guidance from healthcare professionals for any medical conditions.   >>>>>> The expressed opinions belong solely to the hosts and guests, and they do not necessarily reflect the views or opinions of the Hospitals, Clinics, Universities, or any other organization associated with the host or guests.    Disclosures: Ditch The Lab Coat podcast is produced by (Podkind.co) and is independent of Dr. Bonta's teaching and research roles at McMaster University, Temerty Faculty of Medicine and Queens University. 

Coffee is most likely one of your IBS triggers but you just might not know it! I dive into the science of how coffee interacts with our body and gut in this episode.Join the 60 Day gut reset and transform your health! $200OFF with code 'SECRETOFFER! https://checkout.teachable.com/secure/1716725/checkout/order_q9s5bzn3?coupon_code=SECRETOFFERINSTA: @wholistichomeopath

In today's episode, supported by Thermo Fisher Scientific, we had the pleasure of speaking with Apar Kishor Ganti, MD; and Allison Cushman-Vokoun, MD, PhD, FCAP, about the FDA approval of the Oncomine DX Express Test for use as a companion diagnostic for sunvozertinib (Zegfrovy) in EGFR exon 20 insertion mutation–positive non–small cell lung cancer and for use in tumor profiling. Dr Ganti is a professor in the University of Nebraska Medical Center (UNMC) Division of Oncology & Hematology, the Dr. and Mrs. D. Leon UMNC Research Fund Chair in Internal Medicine, and the associate director for Clinical Research at the Fred & Pamela Buffett Cancer Center in Omaha. Dr Cushman is the Henry F. Krous Professor of Pathology, a professor in the UNMC Department of Pathology, Microbiology and Immunology, director of the Division of Diagnostic Molecular Pathology and Human Genetics, medical director of the Molecular Diagnostics and Personalized Medicine Laboratory at Nebraska Medicine, director of the Molecular Genetic Pathology Fellowship Program, and associate director of the UMNC MD-PhD Scholars Program.  In our exclusive interview, Drs Ganti and Cushman discussed the significance of the launch of the Oncomine DX Express Test, the benefits and limitations of rapid next-generation sequencing, and features that set Oncomine DX apart from other available tests. 

Listen as Michael S. Benninger, MD, describes his approach to the diagnosis and management of chronic cough and refractory chronic cough in the context of a clinically relevant case.PresenterMichael S. Benninger, MDProfessor of Otolaryngology-Head and Neck SurgeryLerner College of MedicineThe Cleveland ClinicPresident, International Association of PhonosurgeryCleveland, OhioLink to full program:https://bit.ly/4kweynG

In the 18th century, the average global lifespan was just 28.5 to 32 years. It's now between 72.6 and 73.2. The questions is how can we go and do we really want to? Professor Luke O'Neill Professor of Immunology at Trinity College Dublin discusses all with Ivan.

The Science Behind Chemical Sensitivity with Haylie Pomroy and Dr. Theoharis Theoharides Support the Institute today. https://www.nova.edu/give/index.html?area=Institute%20for%20Neuro-Immune%20Medicine&designation=INIM%20Grateful%20Patient%20Fund  In this episode, Dr. Theoharis Theoharides breaks down the science behind Multiple Chemical Sensitivity (MCS), offering a clear and research-informed perspective on this often misunderstood condition.  He defines what MCS is, how individuals can be triggered by even minimal chemical exposures, and the wide range of symptoms that may follow. He also addresses the serious immunological effects of chemical exposure and emphasizes the importance of creating chemically safe environments. The discussion also covers the role of mast cell activation in MCS, the ways stress can intensify symptoms, and the diagnostic codes currently used for clinical management and treatment.  Tune in to the Hope and Help for Fatigue and Chronic Illness Podcast – The Science Behind Chemical Sensitivity Learn more about INIM's Research Studies: https://www.nova.edu/nim/research-studies/index.html  Sign up for the COVID-UPP Study: https://redcap.nova.edu/redcap/surveys/?s=RMEDJ7LKCX&_gl=1*1h830h7*_gcl_au*MTM2NDA0MTQyOS4xNzE1MDA0ODAy If you are interested in joining a Gulf War Illness (GWI) trial, please complete the Recruitment Registry Form. https://redcap.nova.edu/redcap/surveys/?s=Y9YF8JJWJRK8HEKL%20&_gl=1*1fipp18*_gcl_aw*R0NMLjE3MDc5MTgwMzIuRUFJYUlRb2JDaE1JeWNyUXVfcXFoQU1WU1pCYUJSM3AyQWRBRUFBWUFTQUFFZ0s1NWZEX0J3RQ..*_gcl_au*MTg2NjgwMDQ4Ni4xNzA3MTQwNzgx   Dr. Theoharis Theoharides is a Professor, Vice Chair of Clinical Immunology, and Director at the Institute for Neuro-Immune Medicine-Clearwater, an Adjunct Professor of Immunology at Tufts School of Medicine, where he was a Professor of Pharmacology and Internal Medicine, and also the  Director of Molecular Immunopharmacology & Drug Discovery, and Clinical Pharmacologist at the Massachusetts Drug Formulary Commission (1983-2022). He received his BA, MS, MPhil, PhD, and MD degrees and the Winternitz Price in Pathology from Yale University and received a Certificate in Global Leadership from Tufts Fletcher School of Law and Diplomacy and a Fellowship at Harvard Kennedy  School of Government. He trained in internal medicine at New England Medical Center, which awarded him the Oliver Smith Award, “recognizing excellence, compassion, and service.” Dr. Theoharides has 485 publications (46,491 citations; h-index 106), placing him in the world's top 2% of most cited authors, and he was rated the worldwide expert on mast cells by Expertscape. He was inducted into the Alpha Omega Alpha National Medical Honor Society, the Rare Diseases Hall of Fame, and the World Academy of Sciences.  Website: https://www.drtheoharides.com  LinkedIn: linkedin.com/in/theoharis-theoharides-ms-phd-md-faaaai-67123735   Instagram: https://www.instagram.com/dr.theoharides/   Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet. Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com Instagram: https://www.instagram.com/hayliepomroy  Facebook: https://www.facebook.com/hayliepomroy  YouTube: https://www.youtube.com/@hayliepomroy/videos  LinkedIn: https://www.linkedin.com/in/hayliepomroy/  X: https://x.com/hayliepomroy  Enjoy our show? Please leave us a 5-star review so we can bring hope and help to others. You can also find this show on our YouTube channel. Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d Learn more about the Institute for Neuro-Immune Medicine. Website: https://www.nova.edu/nim/ Facebook: https://www.facebook.com/InstituteForNeuroImmuneMedicine Instagram: https://www.instagram.com/NSU_INIM/ Twitter: https://www.twitter.com/NSU_INIM

Egg freezing is a booming business with a 400 percent increase since 2012. But should men consider freezing their sperm? A study found men's fertility drastically decline for those over the age of 50. Professor of Immunology at Trinity College Dublin Professor Luke O'Neill discusses men's fertility and their options, including freezing their sperm.

Health Secretary Robert F. Kennedy's revamped CDC vaccine advisory board stopped recommending certain flu vaccines this week. On this week's On the Media, a scientist debunks the claims that RFK, Jr.'s appointees are making. Plus, how the media covered the U.S. bombing of Iran.[00:00] Host Micah Loewinger unspools the Trump administration's attempts to control the narrative around the war in Iran, including the president's insistence on the “total obliteration” of Iran's nuclear sites, conflicting reports over whether or not Iran had a nuclear weapons program in the works, and how the media is missing the mark.[00:00] Host Brooke Gladstone speaks with Paul Offit, the director of the Vaccine Education Center and a physician in the Division of Infectious Diseases at Children's Hospital of Philadelphia, about how the Secretary of Health and Human Services, Robert F. Kennedy Jr., purged the CDC's vaccine advisory committee members, the controversial figures Kennedy replaced them with, and what impact this will have on the future of vaccines and immunology in the US. [00:00] Brooke continues her conversation with Paul Offit about the new controversial figures appointed to the CDC's vaccine advisory committee, and how science communication could improve in the next public health crisis.  Further reading:“Lawmakers and Pundits Speed Run Iraq WMDs-Level Lies About Iran,” by Sarah Lazare and Adam Johnson“Donald Trump and Sean Hannity Set Off a Wave of Disinformation After Iran Bombing,” by David Gilbert On the Media is supported by listeners like you. Support OTM by donating today (https://pledge.wnyc.org/support/otm). Follow our show on Instagram, Twitter and Facebook @onthemedia, and share your thoughts with us by emailing onthemedia@wnyc.org.

Dr. Elizabeth Coon and Dr. Peter Novak discuss how central sensitization plays a role in the autonomic symptoms-sings dichotomy and the importance of addressing both conditions for optimal treatment. Show references:  https://www.neurology.org/doi/10.1212/CPJ.0000000000200463 

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While tuberculosis is not a major health issue in New Zealand, worldwide it remains the leading infectious disease killer.   The vaccine against tuberculosis, called BCG, was first developed in France more than 100 years ago using a strain of bacteria that lost its disease-causing ability. Scientists refer to this as a live attenuated vaccine.   On Our Changing World, the Malaghan Institute's Dr Kerry Hilligan explains to Claire Concannon how this old vaccine is teaching researchers new tricks.

Vincent and Cindy discuss differences between MPox-specific T cell responses following infection and vaccination, and lymph node macrophage control of memory B cell localization and trafficking that might be important for choosing which arm to get a vaccine. Hosts: Vincent Racaniello and Cindy Leifer Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Different T memory response to MPox infection or vaccination (Nat Comm 2025) Macrophages direct B cell recall responses after vaccination (Cell 2025) Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

Sometimes, silence comes at a cost. It shows up in missed job offers, overlooked talents, and years spent waiting for recognition that never arrives. Dr. Gertrude Nonterah grew up in a culture where you weren't supposed to promote yourself - you waited for others to notice your brilliance. But after losing her job in 2018, she realized that hard work wasn't enough. If she didn't learn to speak up and share her story, she'd keep getting passed over. Today, Dr. G is the founder of The Bold PhD, where she helps graduate students and PhDs navigate careers beyond academia. She's a medical communications professional with a Ph.D. in Microbiology and Immunology, and she has built a body of work that speaks for itself. In this episode of EDIT HISTORY, Dr. G shares what it really takes to build a career and a personal brand, especially when life doesn't go to plan. From freelancing as a survival strategy to landing speaking gigs at Ivy Leagues, her story is a powerful reminder: Your consistency is your credibility. And if you've ever felt behind, discouraged, or tempted to give up, this episode is for you. Let's dive in. In this episode, we cover:    (00:00) Introduction (02:05) Being passed over for opportunities  (04:41) Work ethic isn't enough (06:16) Feeling helpless amidst unfair circumstances (11:18) Regaining power over your situation (15:27) Building a body of work (20:19) Not quitting = reliability  (23:26) Insecurities Dr. G faced (29:39) Your content is helping people  (34:22) Reviewing Dr. G's past content (41:14) Take back control of your outcomes  (45:45) Actionable takeaways Connect with Dr. Gertrude Nonterah   Website: https://theboldphd.com/  Instagram: https://www.instagram.com/theboldphd  YouTube: https://www.youtube.com/@TheBoldPhD LinkedIn: https://www.linkedin.com/in/geenonterah/  Newsletter: https://view.flodesk.com/pages/63c76e31b4f015f30446ce4d  Connect with Cheryl Lau   Website: https://cheryllau.com  YouTube: https://www.youtube.com/@cheryltheory  Instagram: https://www.instagram.com/cheryltheory LinkedIn: https://www.linkedin.com/in/cheryllau ANNOTATIONS - The Newsletter    The edits that got cut from the podcast. Every interview on EDIT HISTORY runs about 60 minutes. But less than 40 minutes makes it into the final cut. This newsletter is where the rest live. ANNOTATIONS is where I share the 33% I left behind — and the insights that came after we stopped recording. Subscribe at: https://cheryllau.com/email  Contact   Please email hello@cheryllau.com for business inquiries.

Dr. Elizabeth Coon talks with Dr. Peter Novak about how central sensitization plays a role in the autonomic symptoms-sings dichotomy and the importance of addressing both conditions for optimal treatment. Read the related article in Neurology® Clinical Practice.  Disclosures can be found at Neurology.org. 

✨ Ever wondered WHY peanut allergies are suddenly everywhere? Or what your brutal spring allergies are actually trying to tell you?

In this episode of the Root Cause Medicine Podcast, Dr. Kate Kresge sits down with functional immunology expert and educator Dr. Samuel Yanuck to explore one of the most overlooked systems in chronic illness: the immune system. With clarity and compassion, Dr. Yanuck breaks down how immune dysregulation can contribute to complex conditions like depression, neuropathy, migraines, chronic fatigue, and even cardiovascular disease. From brain inflammation and mast cell activation to Epstein-Barr virus and mold, Dr. Yanuck offers a new way of thinking about biology—where inflammation isn't just a symptom, but a system that can be measured, understood, and treated. You'll here them discuss: - Why immunology could be at the root of nearly every chronic illness - The immune pathways that connect depression, anxiety, brain fog, and fatigue - What PANS, PANDAS, and autoimmune encephalitis really are—and why they're often misdiagnosed - How gut, brain, and immune health form a feedback loop - The labs you should run if you suspect chronic immune dysfunction - A framework for evaluating chronic viral infections like EBV and CMV - Natural immune modulators: Chinese skullcap, astragalus, quercetin, sulforaphane, and more - Why personalized immune workups—not protocols—create results Guest Bio: Dr. Samuel Yanuck is a functional medicine clinician and expert educator in functional immunology. He is the creator of Cogence Immunology, a comprehensive online training program that has educated over 9,000 clinicians in over 60 countries. His approach blends immunology, clinical experience, and systems thinking to help providers and patients uncover the true drivers of chronic illness. Dr. Yanuck is also the co-founder of the Yanuck Center for Life and Health in North Carolina, where he sees patients and helps clinicians find root-cause solutions to immune dysfunction through mentorship and collaboration. His work is helping reshape how the next generation of practitioners understand inflammation, autoimmunity, and healing. Order tests through Rupa Health, the BEST place to order functional medicine lab tests from 30+ labs - https://www.rupahealth.com/reference-guide

Send us a textDr. Emia Oppenheim shares the powerful impact of Farm to Early Care and Education programs that connect young children with local food systems through gardening, hands-on learning, and fresh local foods.• Public health nutrition focuses on population-level changes rather than individual interventions• Children's food preferences often develop before age three, making early exposure to fruits and vegetables critical• Farm to ECE uses three core strategies: buying local foods, teaching about agriculture, and hands-on learning• Purchasing local foods creates ripple effects by supporting farmers and strengthening community food systems• ASPHN's FarmWise initiative brings states together through collaborative learning to develop Farm to ECE programs• Strong coalitions with diverse stakeholders drive innovation and sustainability in public health initiatives• Despite funding challenges, states have found creative ways to implement local food purchasing incentives• The next generation of public health professionals brings systems thinking and compassion to food system workVisit asphn.org to learn more about ASPHN's Farm to ECE work, sign up for their newsletter, or join their upcoming webinars and training opportunities.Guest BioEmia Oppenheim, PhD, MPhil, RD, Public Health Consultant and Farm to ECE Programs Director, Association of State Public Health Nutritionists, Dr. Emia Oppenheim is a seasoned public health nutritionist and consultant currently working with the Association of State Public Health Nutritionists (ASPHN) on federal public health initiatives. With a career spanning several decades, she has extensive expertise in nutrition, early childhood health and development, chronic disease prevention and population health. Dr. Oppenheim completed her PhD in Nutritional Biochemistry in 2001, at Cornell University, following an MPhil in Immunology from the University of Sheffield (UK) and a clinical internship for a dietetic registration at the University of Virginia. Dr. Oppenheim was an adjunct lecturer at Cornell and has presented widely on nutrition and child development in the US and UK. Dr. Oppenheim's career has shifted over the years from nutritional biochemistry to public health nutrition with a focus on transforming policies, systems and programs to support healthier environments for children. She began working on public health programs in school districts, later serving as the lead for early childhood obesity prevention programs at the Ohio Department of Health. She now leads ASPHN's national efforts with Federal partners to expand and strengthen Farm to Child initiatives, helping states create healthier food sysLike what you heard? Please like and share wherever you get your podcasts! Connect with Ann: Community Evaluation Solutions How Ann can help: · Support the evaluation capacity of your coalition or community-based organization. · Help you create a strategic plan that doesn't stress you and your group out, doesn't take all year to design, and is actionable. · Engage your group in equitable discussions about difficult conversations. · Facilitate a workshop to plan for action and get your group moving. · Create a workshop that energizes and excites your group for action. · Speak at your conference or event. Have a question or want to know more? Book a call with Ann .Be sure and check out our updated resource page! Let us know what was helpful. Music by Zach Price: Zachpricet@gmail.com

We are surrounded by bold claims and quick fixes for ‘boosting' our immune health. But one thing the science is clear on is that everyone's immune system is unique – what is good for one person may not work well for another. So how do we separate the bogus claims from the useful advice? Head of Life Sciences and Professor of Immunology at Imperial College, Daniel Davis, helps us sort the facts from the fiction. From the genetics of immune health to the myth of Vitamin C, from evidence-backed studies on chronic stress to the gaps in knowledge on sleep and microbiome health, Daniel reveals what scientists do know for certain—and what still needs more answers—to help us make informed choices for ourselves. Learn more about your ad choices. Visit podcastchoices.com/adchoices

n this episode of Psychedelics Today, kicking of Psychedelic Science 2025 week in Denver, we sit down with Jonathan Dicksinson, Chief Executive Officer, and Trevor Millar, Chief Operations Officer of Ambio Life Sciences – one of the world's leading ibogaine clinics – to explore the potential of ibogaine for addiction, neuroregeneration, and how ethics, honoring experience, and sustainability will be key to delivering ibogaine at scale.  Trevor shares his early work supporting marginalized populations in Vancouver's Downtown Eastside, which led to the founding of Liberty Root, one of Canada's first ibogaine clinics. Jonathan reflects on his apprenticeship in Mexican clinics, years of international advocacy with the Global Ibogaine Therapy Alliance, and drafting the first set of clinical guidelines for ibogaine detoxification. Together with paramedic and ibogaine safety protocols expert Jose Inzunza, they co-founded Ambio in Tijuana in 2021. They discuss: The unique safety standards Ambio has pioneered – including industry-wide clinical protocols and magnesium therapy to mitigate cardiac risk. Their scale: over 3,000 patients treated, with 100+ clients per month across five dedicated houses in Baja California. Ambio's groundbreaking neuroregenerative program for Parkinson's, MS, and traumatic brain injury – which has already drawn patients like Brett Favre and Clay Walker. How ibogaine appears to drive profound physiological change – including evidence of TBI reversal as shown in Stanford's 2024 study on Special Forces veterans. Why ibogaine isn't just a molecule – it opens a long-lasting “critical period” of neuroplasticity that must be supported with preparation, integration, and holistic care. The deeper story of sourcing: through his company Terragnosis, Jonathan is the only person with a legal export license for Tabernanthe iboga from Gabon, and Ambio is setting a precedent for reciprocal and ethical global supply chains. Their cautionary perspective on Texas' $50M push toward ibogaine clinical trials – and why the traditional “one drug, one indication” model misses the complexity and promise of psychedelic healing. They also make a compelling case that Ambio is already modeling what the future of psychedelic care should look like – not a single drug in a sterile clinical setting, but a comprehensive, integrated protocol combining preparation, medical oversight, and deep integration. “Start with the end in mind,” Trevor urges – Ambio isn't just part of the movement; it's the blueprint for how ibogaine could be delivered worldwide. Links: Ambio Website: https://ambio.life/ Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis (Frontiers in Immunology, Feb 2025) Magnesium–ibogaine therapy in veterans with traumatic brain injuries (Nature Medicine, Jan 2024) Ibogaine reduced severe neuropathic pain associated with a case of brachial plexus nerve root avulsion (Frontiers in Pain Research, Aug 2023) Novel treatment of opioid use disorder using ibogaine and iboga in two adults (Journal of Psychedelic Studies, Jan 2020) Clinical Guidelines for Ibogaine-Assisted Detoxification Ambio Life Sciences Launches World's First Clinical Ibogaine Program for Patients With Neurodegenerative Conditions Bios:  Jonathan Dickinson is the Chief Executive Officer and Co-Founder of Ambio Life Sciences. One of the world's leading experts on ibogaine, Jonathan brings over 15 years of experience in clinical care, traditional practice, and psychedelic research to his leadership at Ambio. A Mexico-licensed psychologist and former Executive Director of the Global Ibogaine Therapy Alliance, he authored the field's foundational safety guidelines and has published widely on ibogaine's therapeutic, cultural, and ecological significance. He holds the only active export license for Tabernanthe iboga root, led the first Nagoya-compliant export from Gabon, and was initiated into the Dissoumba/Fang tradition of Bwiti in 2014 and the Missoko tradition in 2022. He has co-authored peer-reviewed research on ibogaine's potential for trauma, TBI, pain, MS, and Parkinson's. At Ambio, he leads strategy, research, and innovation – advancing a globally scalable model of care that bridges tradition, science, and integrity. Trevor Millar is the Chief Operating Officer and Co-Founder of Ambio Life Sciences. A social entrepreneur and pioneer in ibogaine advocacy and treatment, Trevor brings over a decade of experience supporting individuals through addiction recovery, trauma healing, and post-treatment integration. His background includes co-founding the Canadian Psychedelic Association and serving as Chair of the Board for MAPS Canada. He has co-authored peer-reviewed research on ibogaine's applications for trauma, TBI, and opioid use disorder, and has been featured in award-winning documentaries including DOSED and In Waves and War. Grounded in personal experience and guided by a philosophical approach to healing, Trevor is helping shape a new model for ethical, integrative psychedelic care on a global scale. At Ambio, Trevor leads operations, strategic partnerships, and client experience – bridging clinical care with systems design, education, and public advocacy.

This episode of High Performance Health is a powerful reminder that the true path to longevity isn’t found in chasing supplement stacks or living to 160—it’s about becoming immune to aging by mastering the fundamentals. Angela sits down with Dr Jenna Macciochi, immunologist, author, and high-performance breathwork coach, to explore how chronic inflammation, lifestyle, mindset, and motherhood all shape our biological age far more than we realize. Dr Jenna's new book Immune to Age presents a revolutionary framework: understanding the immune system as a dynamic force through the seasons of life—from birth to old age. In this heartfelt, science-rich conversation, Jenna and Angela dive into everything from burnout and HRV to intuition, parenting, alcohol, and the myth of the perfect biohacking protocol. This is the longevity conversation every woman needs to hear. KEY TAKEAWAYS: Chronic Inflammation: The Silent Driver of Aging : The immune system's slow burn of inflammation is the root cause behind most chronic diseases and early aging. The Parenting Connection: Children phase-lock to their mother’s HRV—your emotional regulation teaches them how to regulate themselves. Burnout & Intuition: Ignoring your intuition and pushing through stress leads to burnout. Slowing down and listening is the real path to resilience. Longevity Isn’t Just About Data: Healthspan matters more than lifespan. Fancy tests are fun, but it’s the basics—food, movement, sleep, breath—that move the needle. Alcohol, Sleep & Energy: Giving up alcohol even temporarily can have a massive ripple effect on mood, energy, and parenting. Immune System Through the Life Course: From womb to old age, your immune system evolves—and it’s never too early or too late to care for it. TIMESTAMPS AND KEY TOPICS: 0:00 – Introduction 3:49 – Why healthspan matters more than lifespan 8:34 – Advice for working women juggling everything 12:15 – How meditation rewires stress and physiology 16:42 – Garbage time, HRV, and parenting insights 22:23 – Female intuition, hormones & relationships 29:10 – Jenna’s daily health and movement routine 34:28 – Alcohol and the “tiny experiment” approach 41:52 – Jenna’s new book: Immune to Age 49:37 – Cancer, inflammation & microbiome connection 59:24 – How to filter conflicting wellness advice 1:00:16 – Tests that matter (and those that don’t) VALUABLE RESOURCES Get a free snapshot of your health and personalised report at www.yourtotalhealthcheck.com Join The High Performance Health Community Click here for discounts on all the products I personally use and recommend A BIG thank you to our sponsors who make the show possible: LVLUP HEALTH: Slow aging, repair gut health boost collagen and recovery and more with LVLUP Health’s amazing products. Save 15% with code ANGELA at https://lvluphealth.com/angela Get 20% off the Creatine I love at trycreate.co/ANGELA20, and use code ANGELA20 to save 20% on your firsts order. Sign Up to Angela’s Weekly Fresh Starts Email to transform your health, energy, and longevity with just ONE small habit every week - angelafoster.me/freshstart Pre order Dr Jenna’s book: Immune To Age: The Game Changing Science of Immune Health (releasing on 3rd July 2025) ABOUT THE GUEST Based in Brighton, Dr Jenna is a Senior Lecturer in Immunology at The University of Sussex and a fitness instructor and health coach. She integrates her extensive academic knowledge with practical experience, guiding individuals and businesses in the wellness and performance sectors. A certified high-performance breathwork coach, Jenna provides functional breathing assessments and breath training to help clients unlock their full potential and enhance physical and mental well-being and performance. Her expertise in supplement formulation benefits individuals seeking targeted supplement protocols and bloodwork analysis for their health goals. Her expertise in supplement formulation can assist businesses in creating compliant, scientifically-backed health products. She is the author of two seminal books "Immunity: The Science of Staying Well" (Harper Collins, 2020) and "Your Blueprint for Strong Immunity" (Yellow Kite, 2022). Her books combine cutting-edge research with practical advice, making them essential reads for anyone looking to live a healthier life. Jenna loves crafting recipes and rituals inspired by her farm-to-table Scottish roots and capturing her family’s Italian heritage. As a mother of twins and a keen home cook, she brings a personal and realistic touch to her scientifically-baked advice. ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women’s Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. The High Performance Health Podcast is a top rated global podcast. Each week, Angela brings you a new insight, biohack or high performance habit to help you unlock optimal health, longevity and higher performance. Hit the follow button to make sure you get notified each time Angela releases a new episode. CONTACT DETAILS Instagram Facebook LinkedIn Affiliate Disclaimer: Note this description contains affiliate links that allow you to find the items mentioned in this video and support the channel at no cost to you. While this channel may earn minimal sums when the viewer uses the links, the viewer is under no obligation to use these links. Thank you for supporting the show! Disclaimer: The High Performance Health Podcast is for general information purposes only and do not constitute the practice of professional or coaching advice and no client relationship is formed. The use of information on this podcast, or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for medical or other professional advice, diagnosis, or treatment. Users should seek the assistance of their medical doctor or other health care professional for before taking any steps to implement any of the items discussed in this podcast. This Podcast has been brought to you by Disruptive Media. https://disruptivemedia.co.uk/

How are big insurance companies dodging the very rules meant to protect patients — and turning our health care system into a profit machine for Wall Street? What can we the people do to stop it? Join us as we dive into the dark side of corporate loopholes, for-profit health care, and policy failure with Rachel Madley, Director of Policy and Advocacy at the Center for Health and Democracy. A former FDA staffer and health policy advisor to Congresswoman Pramila Jayapal, Rachel played a key role in crafting and reintroducing the House Medicare for All bill in 2023. With a PhD in Microbiology and Immunology from Columbia University, she brings both scientific rigor and firsthand policy experience to this eye-opening conversation.

How are big insurance companies dodging the very rules meant to protect patients — and turning our health care system into a profit machine for Wall Street? What can we the people do to stop it? Join us as we dive into the dark side of corporate loopholes, for-profit health care, and policy failure with Rachel Madley, Director of Policy and Advocacy at the Center for Health and Democracy. A former FDA staffer and health policy advisor to Congresswoman Pramila Jayapal, Rachel played a key role in crafting and reintroducing the House Medicare for All bill in 2023. With a PhD in Microbiology and Immunology from Columbia University, she brings both scientific rigor and firsthand policy experience to this eye-opening conversation. Check out the Transcript and Show Notes for more! And please keep Code WACK! on the air with a tax-deductible donation at heal-ca.org/donate.

Accumulating evidence suggests that a common single-celled parasite called Toxoplasma gondii may be a contributor to affecting male fertility. An April 2025 study published in the FEBS (Federation of European Biochemical Societies) Journal showed for the first time that “human sperm lose their heads upon direct contact” with the parasite. Could this be affecting male fertility? Joining me today to discuss this topic is William Sullivan, PhD. Dr Sullivan is a Professor of Microbiology and Immunology at Indiana University  A common parasite can decapitate human sperm − with implications for male fertility  

Amy MacIver is joined by Professor Elizabeth Mayne, a specialist haematologist and immunopathologist at the University of Cape Town, to unpack new research revealing how our immune system is influenced by light. A recent study from the University of Auckland found that neutrophils — the body’s most abundant white blood cells — are more effective at killing bacteria during the day, thanks to an internal, light-sensitive circadian clock. Presenter John Maytham is an actor and author-turned-talk radio veteran and seasoned journalist. His show serves a round-up of local and international news coupled with the latest in business, sport, traffic and weather. The host’s eclectic interests mean the program often surprises the audience with intriguing book reviews and inspiring interviews profiling artists. A daily highlight is Rapid Fire, just after 5:30pm. CapeTalk fans call in, to stump the presenter with their general knowledge questions. Another firm favourite is the humorous Thursday crossing with award-winning journalist Rebecca Davis, called “Plan B”. Thank you for listening to a podcast from Afternoon Drive with John Maytham Listen live on Primedia+ weekdays from 15:00 and 18:00 (SA Time) to Afternoon Drive with John Maytham broadcast on CapeTalk https://buff.ly/NnFM3Nk For more from the show go to https://buff.ly/BSFy4Cn or find all the catch-up podcasts here https://buff.ly/n8nWt4x Subscribe to the CapeTalk Daily and Weekly Newsletters https://buff.ly/sbvVZD5 Follow us on social media: CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.

This time on CodeWACK! How are big insurance companies dodging the very rules meant to protect patients — and turning our health care system into a profit machine for Wall Street? What can we the people do to stop it? Join us as we dive into the dark side of corporate loopholes, for-profit health care, and policy failure with Rachel Madley, Director of Policy and Advocacy at the Center for Health and Democracy. A former FDA staffer and health policy advisor to Congresswoman Pramila Jayapal, Rachel played a key role in crafting and reintroducing the House Medicare for All bill in 2023. With a PhD in Microbiology and Immunology from Columbia University, she brings both scientific rigor and firsthand policy experience to this eye-opening conversation.   Check out the Transcript and Show Notes for more! And please keep Code WACK! on the air with a tax-deductible donation at heal-ca.org/donate

This time on CodeWACK! How are big insurance companies dodging the very rules meant to protect patients — and turning our health care system into a profit machine for Wall Street? What can we the people do to stop it? Join us as we dive into the dark side of corporate loopholes, for-profit health care, and policy failure with Rachel Madley, Director of Policy and Advocacy at the Center for Health and Democracy. A former FDA staffer and health policy advisor to Congresswoman Pramila Jayapal, Rachel played a key role in crafting and reintroducing the House Medicare for All bill in 2023. With a PhD in Microbiology and Immunology from Columbia University, she brings both scientific rigor and firsthand policy experience to this eye-opening conversation. Check out the Transcript and Show Notes for more! And please keep Code WACK! on the air with a tax-deductible donation at heal-ca.org/donate.

This week on CodeWACK!   Are Americans finally waking up to the truth about single-payer healthcare? With new Medicare for All bills recently reintroduced in Congress, we're setting the record straight. Will it really save us money? Is it socialized medicine? And why aren't our legislators addressing the REAL causes of our skyrocketing healthcare costs? To unpack this, we spoke with Rachel Madley, Director of Policy and Advocacy at the Center for Health and Democracy. A former health policy advisor to Congresswoman Pramila Jayapal — lead sponsor of the House Medicare for All bill — Rachel helped shape and reintroduce the landmark legislation in 2023. She's also a former FDA staffer and holds a PhD in Microbiology and Immunology from Columbia University, where she was active in both Physicians for a National Health Program and Students for a National Health Program. Check out the Transcript and Show Notes for more! And please keep Code WACK! on the air with a tax-deductible donation at heal-ca.org/donate.

This week we speak with Professor Robert Hamilton of the University of Toronto about a recent case-control study in which his team identified a novel auto-antibody targeting a fetal cardiac protein that proved to have excellent sensitivity and specificity for the identification of fetuses that would develop heart block in fetal life in the offspring of women with maternal connective tissue disorders. How did the team in Toronto choose these particular target proteins? How well did this test perform in predicting heart block in pregnancies where there had been a prior pregnancy affected by block? Does this test possibly mean that fewer fetuses of mothers with connective tissue will need surveillance? Dr. Hamilton shares the details of this fascinating study this week. https://doi.org/10.1016/s2665-9913(25)00092-xWe also speak with Drs. David Ezon and Kenan Stern about the upcoming 16th Annual Mount Sinai Imaging Symposium - Conversations in Care: Cardiac Conundrums & 3D Echo Workshop which will be taking place at Mount Sinai on 5/31/25. Details are available at the following website:https://mssm.cloud-cme.com/course/courseoverview?P=5&EID=46043

At the beginning of May, the National Institutes of Health, part of the Department of Health and Human Services, announced a plan to develop a universal vaccine platform. Think: a single shot for flu or COVID-19 that would last years, maybe a lifetime. The plan—called Generation Gold Standard—has a reported budget of $500 million, and a tight deadline. But will it work? And where does the science on this actually stand? In this live broadcast, Hosts Flora Lichtman and Ira Flatow talk with epidemiologist Michael Osterholm and vaccine researcher Ted Ross.Guests: Michael Osterholm is Director of the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota in Minneapolis, Minnesota.Dr. Ted Ross is the global director of vaccine research at the Cleveland Clinic's Florida Research and Innovation Center in Port St. Lucie, Florida. Transcript will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Fungal diseases are becoming more common, more dangerous, and more difficult to treat. There's concern that they may cause the next global pandemic. Rising global temperatures, better survival rates for vulnerable patients, and increased medical interventions contribute to the rise in fungal infections. Access to effective diagnostics and treatment remains limited, with significant disparities between high and low-income countries. Treating fungal infections is becoming more challenging as they build resistance to the drugs used to treat them. New therapies are being developed, including treatments that disrupt fungal DNA replication or interfere with essential proteins, offering some hope for long-term control.Contributors: Adilia Warris, Professor in Paediatric Infectious Diseases, University of Exeter, UKRita Oladele, Professor of Clinical Microbiology, University of Lagos and Lagos University Teaching Hospital, NigeriaArturo Casadevall, Professor and Chair of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, USMichael Bromley, Professor in Fungal Disease, University of Manchester, UKPresenter: Tanya Beckett Producer: Louise Clarke Researcher: Maeve Schaffer Editor: Tara McDermott Technical Producer: Richard Hannaford Production co-ordinator: Tammy Snow(Image: Aspergillus fumigatus, seen under an optical microscope. Credit: BSIP/Education Images/Universal Images Group via Getty Images)

Steph talks about identification of gut bacteria that can digest protective mucosal antibodies and Vincent covers a new paper on Zika virus that implicates fetal phagocytes in brain invasion, which may provide insight into the devastating microcephaly outcome of infection during pregnancy. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Gut bacteria induce mucosal immunodeficiency (Science) Contribution of fetal mononuclear phagocytes to Zika virus neuroinvasion (Cell) TWiV468 discusses Zika and brain slice infection model. Time stamps by Jolene Ramsey. Thanks! Music by Tatami. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv Information on this podcast should not be construed as medical advice.

Donate for chronic fatigue and long COVID research today. https://givenow.nova.edu/donations-for-chronic-fatigue-and-long-covid-research/?a=4951638  In this episode, Haylie Pomroy speaks with Dr. Theoharis Theoharides about the physiological consequences of stress on the body. They discuss how stress impacts the immune system, including its role in both anti-inflammatory and pro-inflammatory responses. Dr. Theoharides explains how mast cells are involved in the body's stress response, the symptoms of mast cell activation, and how to recognize if someone may be experiencing chronic issues. He also shares practical steps to identify when stress is not being managed well and highlights the importance of nutrition and lifestyle in recovery. Tune in to the Hope and Help for Fatigue and Chronic Illness Podcast – The Physiological Consequences of Chronic Stress Sign up for the COVID-UPP Study: https://redcap.nova.edu/redcap/surveys/?s=RMEDJ7LKCX&_gl=1*1h830h7*_gcl_au*MTM2NDA0MTQyOS4xNzE1MDA0ODAy If you are interested in joining a Gulf War Illness (GWI) trial, please complete the Recruitment Registry Form. https://redcap.nova.edu/redcap/surveys/?s=Y9YF8JJWJRK8HEKL%20&_gl=1*1fipp18*_gcl_aw*R0NMLjE3MDc5MTgwMzIuRUFJYUlRb2JDaE1JeWNyUXVfcXFoQU1WU1pCYUJSM3AyQWRBRUFBWUFTQUFFZ0s1NWZEX0J3RQ..*_gcl_au*MTg2NjgwMDQ4Ni4xNzA3MTQwNzgx  Learn more about INIM's Research Studies: https://www.nova.edu/nim/research-studies/index.html Read INIM's latest publication. https://pubmed.ncbi.nlm.nih.gov/40332133/ Dr. Theoharis Theoharides is Professor and Vice Chair of Clinical Immunology and Director at the Institute for Neuro-Immune Medicine–Clearwater. He is also Adjunct Professor of Immunology at Tufts School of Medicine, where he previously served as Professor of Pharmacology and Internal Medicine, and Director of Molecular Immunopharmacology & Drug Discovery. He earned multiple advanced degrees (BA, MS, MPhil, PhD, MD) from Yale University, received a Certificate in Global Leadership from Tufts Fletcher School, and completed a fellowship at Harvard Kennedy School. With over 485 publications and an h-index of 106, he ranks among the top 2% of most-cited researchers and was named the leading global expert on mast cells by Expertscape. His honors include induction into Alpha Omega Alpha, the Rare Diseases Hall of Fame, and the World Academy of Sciences. Website: https://www.drtheoharides.com  LinkedIn: linkedin.com/in/theoharis-theoharides-ms-phd-md-faaaai-67123735   Instagram: https://www.instagram.com/dr.theoharides Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet. Website: https://hayliepomroy.com/podcast Instagram: https://www.instagram.com/hayliepomroy  Facebook: https://www.facebook.com/hayliepomroy  LinkedIn: https://www.linkedin.com/in/hayliepomroy/  X: https://x.com/hayliepomroy  TikTok: https://tiktok.com/@hayliepomroy Enjoy our show? Please leave us a 5-star review so we can bring hope and help to others. Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d Learn more about the Institute here. Website: https://www.nova.edu/nim/ Facebook: https://www.facebook.com/InstituteForNeuroImmuneMedicine Instagram: https://www.instagram.com/NSU_INIM/ Twitter: https://www.twitter.com/NSU_INIM

Do your seasonal allergies feel worse this spring? You might not be imagining it: climate change is hastening the end of winter, pushing up pollen production and intensifying winds that spread allergens around. We'll talk to doctors about the science of seasonal allergies, learn why some of us are more vulnerable to them than others and hear how to get relief from all the sniffing, scratching and sneezing. Guests: Dr. Sayantani (Tina) Sindher, Clinical Associate Professor of Allergy and Immunology, Stanford University School of Medicine Learn more about your ad choices. Visit megaphone.fm/adchoices

Tetanus has probably been around for most of human history, or even longer. But it’s preventable today thanks to vaccines. Research: "Emil von Behring." Notable Scientists from 1900 to the Present, edited by Brigham Narins, Gale, 2008. Gale In Context: Science, link.gale.com/apps/doc/K1619001490/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=464250e5. Accessed 17 Apr. 2025. Breasted, J.H., translator. “OIP 3. The Edwin Smith Surgical Papyrus, Volume 1: Hieroglyphic Transliteration, Translation, and Commentary.” Oxford University Press. 1930. Chalian, William. “An Essay on the History of Lockjaw.” Bulletin of the History of Medicine, FEBRUARY, 1940, Vol. 8, No. 2. Via JSTOR. https://www.jstor.org/stable/44446242 Emil von Behring: The founder of serum therapy. NobelPrize.org. Nobel Prize Outreach 2025. Thu. 17 Apr 2025. https://www.nobelprize.org/prizes/medicine/1901/behring/article/ Galassi, Francesco Maria et al. “Tetanus: historical and palaeopathological aspects considering its current health impact.” Journal of preventive medicine and hygiene vol. 65,4 E580-E585. 31 Jan. 2025, doi:10.15167/2421-4248/jpmh2024.65.4.3376 George, Elizabeth K. “Tetanus (Clostridium tetani Infection).” StatPearls. January 2025. https://www.ncbi.nlm.nih.gov/books/NBK482484/ Hippocrates. “VI. Diseases, Internal Affections.” Harvard University Press. 1988. Jean-Marc Cavaillon, Historical links between toxinology and immunology, Pathogens and Disease, Volume 76, Issue 3, April 2018, fty019, https://doi.org/10.1093/femspd/fty019 Jones CE, Yusuf N, Ahmed B, Kassogue M, Wasley A, Kanu FA. Progress Toward Achieving and Sustaining Maternal and Neonatal Tetanus Elimination — Worldwide, 2000–2022. MMWR Morb Mortal Wkly Rep 2024;73:614–621. DOI: http://dx.doi.org/10.15585/mmwr.mm7328a1 Kaufmann, Stefan H E. “Remembering Emil von Behring: from Tetanus Treatment to Antibody Cooperation with Phagocytes.” mBio vol. 8,1 e00117-17. 28 Feb. 2017, doi:10.1128/mBio.00117-17 Kreston, Rebecca. “Tetanus, the Grinning Death.” Discover. 9/29/2015. https://www.discovermagazine.com/health/tetanus-the-grinning-death Milto, Lori De, and Leslie Mertz, PhD. "Tetanus." The Gale Encyclopedia of Public Health, edited by Brigham Narins, 2nd ed., vol. 2, Gale, 2020, pp. 1074-1076. Gale In Context: Environmental Studies, link.gale.com/apps/doc/CX7947900274/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=a44bc544. Accessed 14 Apr. 2025. Milto, Lori De, and Leslie Mertz, PhD. "Tetanus." The Gale Encyclopedia of Public Health, edited by Brigham Narins, 2nd ed., vol. 2, Gale, 2020, pp. 1074-1076. Gale In Context: Environmental Studies, link.gale.com/apps/doc/CX7947900274/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=a44bc544. Accessed 15 Apr. 2025. National Institutes of Health. “Tetanus.” https://history.nih.gov/display/history/Tetanus Ni, Maoshing. “The Yellow Emperor's Classic of Medicine: A New Translation of the Neijing Suwen with Commentary.” Shambhala. 1995. Smithsonian. “The Antibody Initiative: Battling Tetanus.” https://www.si.edu/spotlight/antibody-initiative/battling-tetanus Sundwall, John. “Man and Microbes.” Illustrated lecture given under the auspices of the Kansas Academy of Science, Topeka, January 12, 1917. https://archive.org/details/jstor-3624335/ The Nobel Prize in Physiology or Medicine 1901. NobelPrize.org. Nobel Prize Outreach 2025. Thu. 17 Apr 2025. https://www.nobelprize.org/prizes/medicine/1901/summary/ Tiwari, Tejpratap S.P. et al. “Chapter 21: Tetanus.” CDC Pink Book. https://www.cdc.gov/pinkbook/hcp/table-of-contents/chapter-21-tetanus.html Von Behring, Emil and Kitasato Shibasaburo. “The Mechanism of Immunity in Animals to Diphtheria and Tetanus.” Immunology. 1890. http://raolab.org/upfile/file/20200612164743_201234_56288.pdf War Office Committee for the Study of Tetanus. “Memorandum on Tetanus.” Fourth Edition. 1919. https://archive.org/details/b32171201/ World Health Organization. “Tetanus.” 7/12/2024. https://www.who.int/news-room/fact-sheets/detail/tetanus See omnystudio.com/listener for privacy information.