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The Blizzard of 2026 was supposed to shut everything down with up to 3 feet of snow. Instead, Shawna and LaLa got 8 inches while Long Island got buried… allegedly 30 inches. Or 30 feet if you ask Shawna. LaLa sounds off on facts over feelings when it comes to Botox, viral hot takes, and why emotion should not replace evidence. Plus, powerful interviews with Cindy Yates, CEO of PiperBlue Organics, on clean beauty and confidence, and Dr. Kara Wada, board certified allergist, immunologist, and functional medicine physician, breaking down inflammation, immune health, and advocating for yourself in a broken system.
In episode 69 of Going anti-Viral, Dr Kevin Saunders joins host Dr Michael Saag to discuss a plenary presentation he gave at the 2026 Conference on Retroviruses and Opportunistic Infections (CROI) entitled Successes in HIV-1 Vaccine Design: Accelerating Completion of One of Sciences' Most Difficult Vaccines. Dr Saunders is the associate director for the Duke Human Vaccine Institute and the Norman L. Letvin Professor in Immunology and Infectious Diseases Research. Dr Saunders leads a translational research program that designs and evaluates HIV-1 vaccines. Dr Saunders shares his journey from studying T-cell immunity to pioneering HIV vaccine research. He discusses the challenges of developing an HIV vaccine, the promise of broad neutralizing antibodies, and the innovative use of mRNA technology. Dr Saunders also shares his outlook and optimism for the next 5 years of HIV vaccine development including the use machine learning and artificial intelligence technologies to accelerate the development timeline.0:00 – Introduction 1:36 – Path to HIV research and vaccine development3:50 – Understanding T-cell immunity and HIV6:53 – Transition to passive immunity and broad neutralizing antibodies11:35 – Challenges in developing an HIV vaccine15:25 – Current state of HIV vaccine research17:38 – The role of immunogens in vaccine development20:30 – Combining B-cell and T-cell responses24:59 – Prospect for a HIV vaccine within the next 5 yearsResources:CROI 2026: https://www.croiconference.org/Duke Human Vaccine Institute - https://dhvi.duke.edu/__________________________________________________Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral's host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.Follow Going anti-Viral on: Apple Podcasts YouTubeXFacebookInstagram...
Bone loss doesn't start when fractures happen — it begins years earlier. In this episode, we explore how bone aging accelerates during menopause and the emerging role of the gut microbiome as a driver of skeletal decline. Dr. Kara Fitzgerald speaks with research scientists from Sōlaria biō, the company behind Bōndia, about their work studying plant-derived microbes, microbial synergies, and the connections between gut health, inflammation, and bone loss in peri- and postmenopausal women. We also review findings from a randomized, placebo-controlled clinical trial examining a microbiome-based intervention for bone health — and discuss why bone loss may need to be addressed earlier, systemically, and beyond hormones alone. Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/ GUEST DETAILS Alicia Ballok, Ph.D. is Director of Discovery at Sōlaria biō, leading research on plant-derived synbiotics for inflammatory and immune-mediated diseases. Trained in Microbiology and Immunology at Dartmouth, with postdoctoral work at Harvard Medical School and Massachusetts General Hospital, her work focuses on translating host–microbe science into therapeutic innovation. Mark Charbonneau, Ph.D. is Vice President of R&D at Sōlaria biō. He earned his Ph.D. in Computational and Systems Biology at Washington University in St. Louis, studying infant microbiome development and undernutrition. His work spans microbiome research, bioinformatics, and live biotherapeutic innovation. THANKS TO OUR SPONSOR Sōlaria biō: http://bit.ly/SolariaBio EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS Looking for a clinically proven way to target bone loss? Bōndia by Sōlaria biō is a groundbreaking blend of plant-derived prebiotics and probiotics shown in a clinical trial to improve bone density outcomes by 85%. Try it for yourself at Sōlaria biō and use code Kara20 for 20% off your order. CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw
Luke O'Neill, Professor of Biochemistry and Immunology at Trinity College, talks to Brendan about ‘Sniper's Alley' - the period of time around your fifties when you start becoming more susceptible to negative health events. He explains how to bulletproof yourself before you enter Sniper's Alley and has general tips for better health for us all.
Dr. Susan Wynn earned her DVM from the University of Georgia in 1987. After graduation, she completed a Small Animal Internship and worked in small animal practice for a few years before doing Post-Doctoral work in Immunology and Molecular Pathogenesis. Afterwards. she went back into private practice. She completed a clinical residency in Small Animal Nutrition and was Board Certified in Veterinary Nutrition in 2016. She is currently the Senior Director of Scientific Affairs for Instinct Pet Food.Dr. Wynn has authored three textbooks on integrative medicine, published numerous scientific papers, has lectured extensively on holistic medicine and nutrition, and has been very active in organized veterinary medicine, including founding the Veterinary Botanical Medical Association and serving as President of both the AHVMA and the AAVA. She has been a leader and an inspiration in integrative veterinary medicine for decades.Please enjoy this conversation with Dr. Susan Wynn as we discuss her education, work history, and how Instinct Pet Food supports research, veterinary outreach, and has outstanding sourcing and processing practices.
Dr. Earl J. Campazzi is board certified and has trained and practiced at some of the finest medical institutions in the country. At the Mayo Clinic in Rochester, Minnesota, Dr. Campazzi spent several years on staff providing medical care and teaching resident physicians. He completed his medical training at The Johns Hopkins University and served as chief resident. He earned his medical doctorate from the University of Pittsburgh School of Medicine. Dr. Campazzi holds additional postgraduate degrees including a Master of Public Health with emphasis in Health Care Policy and Management and a Master of Health Sciences with emphasis in Immunology and Infectious Diseases, both from The Johns Hopkins University Bloomberg School of Public Health. In 2020, he completed The Stanford Genetics and Genomics Certificate program at Stanford University. Dr. Campazzi also earned his Master of Business Administration with Health Services Management concentration from Duke University Fuqua School of Business. He completed his Bachelor of Arts at The Johns Hopkins University.Support the show
Episode 43 - Wendy Elverson - Managing Food Protein–Induced Allergic Proctocolitis (FPIAP)In this episode of Nutrition Pearls: the Podcast, co-hosts Megan Murphy and Bailey Koch speak with Wendy Elverson, RD, CSP, LDN about the latest research and best practice for managing infants with Food Protein-Induced Allergic Proctocolitis (FPIAP). Wendy is a registered dietitian who has specialized in clinical pediatric nutrition for more than 25 years. Currently, she is a Senior Clinical Nutrition Specialist at Boston Children's, with expertise in pediatric food allergies and feeding disorders. Wendy is a provider in several multidisciplinary, allergy-focused clinics, including the Atopic Dermatitis Center, the FPIES Clinic, and the EGID Clinic. Wendy has been an active member of CPNP since 2015 and has had many roles, currently serving on the NASPGHAN Public Education Committee. Wendy was the previous Chair of INDANA (International Network for Diet and Nutrition in Allergy) and is the current chair of the Nutrition Work Group of the Allied Health Assembly of the American Academy of Allergy, Asthma, and Immunology (AAAAI). She is a proud co-author of several publications, including a free resource for caregivers of children with milk and egg allergies, tolerant to baked milk and egg, Muffins and More: A Baked Milk and Baked Egg Recipe and Guidebook. Wendy was also the recipient of the 2025 CPNP Dietitian of Excellence Award. References: Mahoney, L. B., et al. (2025). Food protein-induced allergic proctocolitis: What do we know and where are we going? Current Treatment Options in Pediatrics, 11(1). https://doi.org/10.1007/s40746-025-00346-4Meyer, R., et al. (2025). An update on the diagnosis and management of non-IgE-mediated food allergies in children. Pediatric Allergy and Immunology, 36(3). https://doi.org/10.1111/pai.70060 Franco, C., Fente, C., Sánchez, C., Lamas, A., Cepeda, A., Leis, R., & Regal, P. (2022). Cow's Milk Antigens Content in Human Milk: A Scoping Review. In Foods (Vol. 11, Issue 12). https://doi.org/10.3390/foods11121783Gamirova, A., et al. (2022). Food proteins in human breast milk and probability of IgE-mediated allergic reaction during breastfeeding: A systematic review. Journal of Allergy and Clinical Immunology: In Practice, 10(5). https://doi.org/10.1016/j.jaip.2022.01.028Meyer, R., et al. (2023). WAO DRACMA guideline update VII: Milk elimination and reintroduction in cow's milk allergy diagnosis. World Allergy Organization Journal, 16(7). https://doi.org/10.1016/j.waojou.2023.100785Produced by: Corey IrwinNASPGHAN - Council for Pediatric Nutrition Professionalscpnp@naspghan.org
JCO PO author Dr. Foldi at UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine shares insights into the JCO PO article, "Personalized Circulating Tumor DNA Testing for Detection of Progression and Treatment Response Monitoring in Patients With Metastatic Invasive Lobular Carcinoma of the Breast." Host Dr. Rafeh Naqash and Dr. Foldi discuss how serial ctDNA testing in patients with mILC is feasible and may enable personalized surveillance and real-time therapeutic monitoring. TRANSCRIPT Dr. Rafeh Naqash: Hello, and welcome to JCO Precision Oncology Conversations, where we bring you engaging conversations with authors of clinically relevant and highly significant JCO PO articles. I am your host, Dr. Rafeh Naqash, podcast editor for JCO Precision Oncology and Associate Professor at the OU Health Stephenson Cancer Center at the University of Oklahoma. Today, we are thrilled to be joined by Dr. Julia Foldi, Assistant Professor of Medicine in the Division of Hematology-Oncology at University of Pittsburgh School of Medicine and the Magee-Womens Hospital of the UPMC. She is also the lead and corresponding author of the JCO Precision Oncology article entitled "Personalized Circulating Tumor DNA Testing for Detection of Progression and Treatment Response Monitoring in Patients with Metastatic Invasive Lobular Carcinoma of the Breast." At the time of this recording, our guest's disclosures will be linked in the transcript. Julia, welcome to our podcast, and thank you for joining us today. Dr. Julia Foldi: Thank you so much for having me. It is a pleasure. Dr. Rafeh Naqash: Again, your manuscript and project address a few interesting things, so we will start with the basics, since we have a broad audience that comprises trainees, community oncologists, and obviously precision medicine experts as well. So, let us start with invasive lobular breast carcinoma. I have been out of fellowship for several years now, and I do not know much about invasive lobular carcinoma. Could you tell us what it is, what some of the genomic characteristics are, why it is different, and why it is important to have a different way to understand disease biology and track disease status with this type of breast cancer? Dr. Julia Foldi: Yes, thank you for that question. It is really important to frame this study. So, lobular breast cancers, which we shorten to ILC, are the second most common histologic subtype of breast cancer after ductal breast cancers. ILC makes up about 10 to 15 percent of all breast cancers, so it is relatively rare, but in the big scheme of things, because breast cancer is so common, this represents actually over 40,000 new diagnoses a year in the US of lobular breast cancers. What is unique about ILC is it is characterized by loss of an adhesion molecule, E-cadherin. It is encoded by the CDH1 gene. What it does is these tumors tend to form discohesive, single-file patterns and infiltrate into the tumor stroma, as opposed to ductal cancers, which generally form more cohesive masses. As we generally explain to patients, ductal cancers tend to form lumps, while lobular cancers often are not palpable because they infiltrate into the stroma. This creates several challenges, particularly when it comes to imaging. In the diagnostic setting, we know that mammograms and ultrasounds have less sensitivity to detect lobular versus ductal breast cancer. When it comes to the metastatic setting, conventional imaging techniques like CT scans have less sensitivity to detect lobular lesions often. One other unique characteristic of ILC is that these tumors tend to have lower proliferation rates. Because our glucose-based PET scans depend on glucose uptake of proliferating cells, often these tumors also are not avid on conventional FDG-PET scans. It is a challenge for us to monitor these patients as they go through treatment. If you think about the metastatic setting, we start a new treatment, we image people every three to four cycles, about every three months, and we combine the imaging results with clinical assessment and tumor markers to decide if the treatment is working. But if your imaging is not reliable, sometimes even at diagnosis, to really detect these tumors, then really, how are we following these patients? This is really the unique challenge in the metastatic setting in patients with lobular breast cancer: we cannot rely on the imaging to tell if patients are responding to treatment. This is where liquid biopsies are really, really important, and as the field is growing up and we have better and better technologies, lobular breast cancer is going to be a field where they are going to play an important role. Dr. Rafeh Naqash: Thank you for that easy-to-understand background. The second aspect that I would like to have some context on, to help the audience understand why you did what you did, is ctDNA, tumor informed and non-informed. Could you tell us what these subtypes of liquid biopsies are and why you chose a tumor informed assay for your study? Dr. Julia Foldi: Yes, it is really important to understand these differences. As you mentioned, there are two main platforms for liquid biopsy assays, circulating tumor DNA assays. I think what is more commonly used in the metastatic setting are non-tumor informed assays, or agnostic assays. These are generally next-generation sequencing-based assays that a lot of companies offer, like Guardant, Tempus, Caris, and FoundationOne. These do not require tumor tissue; they just require a blood sample, a plasma sample, essentially. The next-generation sequencing is done on cell-free DNA that is extracted from the plasma, and it is looking for any cell-free DNA and essentially, figuring out what part of the cell-free DNA comes from the tumor is done through a bioinformatics approach. Most of these assays are panel tests for cancer-associated mutations that we know either have therapeutic significance or biologic significance. So, the results we receive from these tests generally read out specific mutations in oncogenic genes, or sometimes things like fusions where we have specific targeted drugs. Some of the newer assays can also read out tumor fraction; for example, the newest generation Guardant assay that is methylation-based, they can also quantify tumor fraction. But the disadvantage of the tumor agnostic approach is that it is a little bit less sensitive. Opposed to that, we have our tumor informed tests, and these require tumor tissue. Essentially, the tumor is sequenced; this can either be whole exome or whole genome sequencing. The newer generation assays are now using whole genome sequencing of the tumor tissue, and a personalized, patient-specific panel of alterations is essentially barcoded on that tumor tissue. This can be either structural variants or it can be mutations, but generally, these are not driver mutations, but sort of things that are present in the tumor tissue that tend to stay unchanged over time. For each particular patient, a personalized assay, if you want to call it a fingerprint or barcode, is created, and then that is what then is used to test the plasma sample. Essentially, you are looking for that specific cancer in the blood, that barcode or fingerprint in the blood. Because of this, this is a much more sensitive way of looking for ctDNA, and obviously, this detects only that particular tumor that was sequenced originally. So, it is much more sensitive and specific to that tumor that was sequenced. You can argue for both approaches in different settings. We use them in different settings because they give us different information. The tumor agnostic approach gives us mutations, which can be used to determine what the next best therapy to use is, while the tumor informed assay is more sensitive, but it is not going to give us information on therapeutic targets. However, it is quantified, and we can follow it over time to see how it changes. We think that it is going to tell us how patients respond to treatment because we see our circulating tumor DNA levels rise and fall as the cancer burden increases or decreases. We decided to use the tumor informed approach in this particular study because we were really interested in how to determine if patients are having response to treatment versus if they are going to progress on their treatment, more so than looking for specific mutations. Dr. Rafeh Naqash: When you think about these tumor informed assays and you think about barcoding the mutations on the original tumor that you try to track or follow in subsequent blood samples, plasma samples, in your experience, if you have done it in non-lobular cancers, do you think shedding from the tumor has something to do with what you capture or how much you capture? Dr. Julia Foldi: Absolutely. I think there are multiple factors that go into whether someone has detectable ctDNA or not, and that has to do with the type of cancer, the location, right, where is the metastatic site? This is something that we do not fully understand yet: what are tumors that shed more versus not? There is also clearance of ctDNA, and so how fast that clearance occurs is also something that will affect what you can detect in the blood. ctDNA is very short-lived, only has a half-life of hours, and so you can imagine that if there is little shedding and a lot of excretion, then you are not going to be detecting a lot of it. In general, in the metastatic setting, we see that we can detect ctDNA in a lot of cases, especially when patients are progressing on treatment, because we imagine their tumor burden is higher at that point. Even with the non-tumor informed assays, we detect a lot of ctDNA. Part of this study was to actually assess: what is the proportion of patients where we can have this information? Because if we are only going to be able to detect ctDNA in less than 50 percent of patients, then it is not going to be a useful method to follow them with. Because this field is new and we have not been using a lot of tumor informed assays in the metastatic setting, we did not really know what to expect when we set out to look at this. We did not know what was going to be the baseline detection rate in this patient population, so that was one of the first things that we wanted to answer. Dr. Rafeh Naqash: Excellent. Now going to this manuscript in particular, what was the research question, what was the patient population, and what was the strategy that you used to investigate some of these questions? Dr. Julia Foldi: So, we partnered with Natera, and the reason was that their Signatera tumor-informed assay was the first personalized, tumor-informed, really an MRD assay, minimal residual disease detection assay. It has been around the longest and has been pretty widely used commercially already, even though some of our data is still lacking. but we know that people are using this in the real world. We wanted to gather some real-world data specifically in lobular patients. So, we asked Natera to look at their database of commercial Signatera testing and look for patients with stage 4 lobular breast cancer. The information all comes from the submitting physicians sending in pathologic reports and clinical notes, and so they have that information from the requisitions essentially that are sent in by the ordering physician. We found 66 patients who were on first-line or close to first-line endocrine-based therapies for their metastatic lobular breast cancer and had serial collections of Signatera tests. The way we defined baseline was that the first Signatera had to be sent within three months of starting treatment. So, it is not truly baseline, but again, this is a limitation of looking at real-world data is that you are not always going to get the best time point that you need. We had over 350 samples from those 66 patients, again longitudinal ctDNA samples, and our first question was what is the baseline detection rate using this tumor informed assay? Then, most importantly, what is the concordance between changes in ctDNA and clinical response to treatment? That is defined by essentially radiologic response to treatment. Dr. Rafeh Naqash: Interesting. So, what were some of your observations in terms of ctDNA dynamics, whether baseline levels made a difference, whether subsequent levels at different time points made a difference, or subsequent levels at, let us say, cycle three made a difference? Were there any specific trends that you saw? Dr. Julia Foldi: So, first, at baseline, 95 percent of patients had detectable ctDNA, which is, I think, a really important data point because it tells us that this can be a really useful test. If we can detect it in almost all patients before they start treatment, we are going to be able to follow this longitudinally. And again, these were not true baseline samples. So, I think if we look really at baseline before starting treatment, almost all patients will have detectable ctDNA in the metastatic setting. The second important thing we saw was that disease progression correlated very well with increase in ctDNA. So, in most patients who had disease progression by imaging, we saw increase in ctDNA. Conversely, in most patients who had clinical benefit from their treatment, so they had a response or stable disease, we saw decrease in ctDNA levels. It seems that what we call molecular response based on ctDNA is tracking very nicely along with the radiographic response. So, those were really the two main observations. Again, this is a small cohort, limited by its real-world nature and the time points that ctDNA assay was sent was obviously not mandated. This is a real-world data set, and so we could not really look at specific time points like you asked about, let us say, cycle three of therapy, right? We did not have all of the right time points for all of the patients. But what we were able to do was to graph out some specific patient scenarios to illustrate how changes in ctDNA correlate with imaging response. I can talk a little bit about that. Dr. Rafeh Naqash: That was going to be my question. Did you see patients who had serial monitoring using the tumor informed ctDNA assay where the assay became positive a few months before the imaging? Did you have any of those kinds of observations? Dr. Julia Foldi: Yes, so I think this is where the field is going: are we able to use this technology to maybe detect progression before it becomes clinically apparent? Of course, there are lots of questions about: does that really matter? But it seems like, based on some of the patient scenarios that we present in the paper, that this testing can do that. So, we had a specific scenario, and this is illustrated in a figure in the paper, really showing the treatment as well as the changes in ctDNA, tumor markers, and also radiographic response. So, this particular patient was on first-line endocrine therapy and CDK4/6 inhibitor with palbociclib. Initially, she had a low-level detectable ctDNA. It became undetectable during treatment, and the patient had a couple of serial ctDNA assays that were negative, so undetectable. And then we started, after about seven months on this combination therapy, the ctDNA levels started rising. She actually had three serial ctDNA assays with increasing level of ctDNA before she even had any imaging tests. And then around the time that the ctDNA peaked, this patient had radiographic evidence of progression. There was also an NGS-based assay sent to look for specific mutations at that point. The patient was found to have an ESR1 mutation, which is very common in this patient population. She was switched to a novel oral SERD, elacestrant, and the ctDNA fell again to undetectable within the first couple months of being on elacestrant. And then a very similar thing happened: while she was on this second-line therapy, she had three serial negative ctDNA assays, and then the fourth one was positive. This was two months before the patient had a scan that showed progression again. Dr. Rafeh Naqash: And Julia, like you mentioned, this is a small sample size, limited number of patients, in this case, one patient case scenario, but provides insights into other important aspects around escalation or de-escalation of therapy where perhaps ctDNA could be used as an integral biomarker rather than an exploratory biomarker. What are some of your thoughts around that and how is the breast cancer space? I know like in GI and bladder cancer, there has been a significant uptrend in MRD assessments for therapeutic decision making. What is happening in the breast cancer space? Dr. Julia Foldi: So, super interesting. I think this is where a lot of our different fields are going. In the breast cancer space, so far, I have seen a lot of escalation attempts. It is not even necessarily in this particular setting where we are looking at dynamics of ctDNA, but in the breast cancer world, of course, we have a lot of data on resistance mutations. I mentioned ESR1 mutation in a particular patient in our study. ESR1 mutations are very common in patients with ER-positive breast cancer who are on long-term endocrine therapy, and ESR1 mutations confer resistance to aromatase inhibitors. So, that is an area that there has been a lot of interest in trying to detect ESR1 mutations earlier and switching therapy early. So, this was the basis of the SERENA-6 trial, which was presented last year at ASCO and created a lot of excitement. This was a trial where patients had non-tumor-informed NGS-based Guardant assay sent every three to six months while they were on first-line endocrine therapy with a CDK4/6 inhibitor. If they had an ESR1 mutation detected, they were randomized to either continue the same endocrine therapy or switch to an oral SERD. The trial showed that the population of patients who switched to the oral SERD did better in terms of progression-free survival than those who stayed on their original endocrine therapy. There are a lot of questions about how to use this in routine practice. Of course, it is not trivial to be sending a ctDNA assay every three to six months. The rate of detection of these mutations was relatively low in that study; again, the incidence increases in later lines of therapy. So, there are a lot of questions about whether we should be doing this in all of our first-line patients. The other question is, even the patients who stayed on their original endocrine therapy were able to stay on that for another nine months. So, there is this question of: are we switching patients too early to a new line of therapy by having this escalation approach? So, there are a lot of questions about this. As far as I know, at least in our practice, we are not using this approach just yet to escalate therapy. Time will tell how this all pans out. But I think what is even more interesting is the de-escalation question, and I think that is where tumor informed assays like Signatera and the data that our study generated can be applied. Actually, our plan is to generate some prospective data in the lobular breast cancer population, and I have an ongoing study to do that, to really be able to tease out the early ctDNA dynamics as patients first start on endocrine therapy. So, this is patients who are newly diagnosed, they are just starting on their first-line endocrine therapy, and measure, with sensitive assays, measure ctDNA dynamics in the first few months of therapy. In those patients who have a really robust response, that is where I think we can really think about de-escalation. In the patients whose ctDNA goes to undetectable after just a few weeks of therapy with just an endocrine agent, they might not even need a CDK4/6 inhibitor in their first-line treatment. So, that is an area where we are very interested in our group, and I know that other groups are looking at this too, to try to de-escalate therapy in patients who clear their ctDNA early on. Dr. Rafeh Naqash: Thank you so much. Well, lots of questions, but at the same time, progress comes through questions asked, and your project is one of those which is asking an interesting question in a rarer cancer and perhaps will lead to subsequent improvement in how we monitor these individuals and how we escalate or de-escalate therapy. Hopefully, we will get to see more of what you are working on in subsequent submissions to JCO Precision Oncology and perhaps talk more about it in a couple of years and see how the space and field is moving. Thanks again for sharing your insights. I do want to take one to two quick minutes talking about you as an investigator, Julia. If you could speak to your career pathway, your journey, the pathway to mentorship, the pathway to being a mentor, and how things have shaped for you in your personal professional growth. Dr. Julia Foldi: Sure, yeah, that is great. Thank you. So, I had a little bit of an unconventional path to clinical medicine. I actually thought I was going to be a basic scientist when I first started out. I got a PhD in Immunology right out of college and was studying not even anything cancer-related. I was studying macrophage signaling in inflammatory diseases, but I was in New York City. This was right around the time that the first checkpoint inhibitors were approved. Actually, some of my friends from my PhD program worked in Jim Allison's lab, who was the basic scientist responsible for ipilimumab. So, I got to kind of first-hand experience the excitement around bringing something from the lab into the clinic that actually changed really the course of oncology. And so, I got very excited about oncology and clinical medicine. So, I decided to kind of switch gears from there and I went back to medical school after finishing my PhD and got my MD at NYU. I knew I wanted to do oncology, so I did a research track residency and fellowship combined at Yale. I started working early on with the breast cancer team there. At the time, Lajos Pusztai was the head of translational research there at Yale, and I started working with him early in my residency and then through my fellowship. I worked on several trials with him, including a neoadjuvant checkpoint inhibitor trial in triple-negative breast cancer patients. During my last year in fellowship, I received a Conquer Cancer Young Investigator Award to study estrogen receptor heterogeneity using spatial transcriptomics in this subset of breast cancers that have intermediate estrogen receptor expression. From there, I joined the faculty at the University of Pittsburgh in 2022. So, I have been there about almost four years at this point. My interests really shifted slowly from triple-negative breast cancers towards ER-positive breast cancers. When I arrived in Pittsburgh, I started working very closely with some basic and translational researchers here who are very interested in estrogen signaling and mechanisms of resistance to endocrine therapy, and there is a large group here interested in lobular breast cancers. During my training, I was not super aware even that lobular breast cancer was a unique subtype of breast cancers, and that is, I think, changing a little bit. There is a lot more awareness in the breast cancer clinical and research community about ILC being a unique subtype, but it is not even really part of our training in fellowship, which we are trying to change. But I have become a lot more aware of this because of the research team here and through that, I have become really interested also on the clinical side. And so, we do have a Lobular Breast Cancer Research Center of Excellence here at the University of Pittsburgh and UPMC, and I am the leader on the clinical side. We have a really great team of basic and translational researchers looking at different aspects of lobular breast cancers, and some of the work that I am doing is related to this particular manuscript we discussed and the next steps, as I mentioned, a prospective study of early ctDNA dynamics in lobular patients. I also did some more clinical research work in collaboration with the NSABP looking at long-term outcomes of patients with lobular versus ductal breast cancers in some of their older trials. And so, that is, in a nutshell, a little bit about how I got here and how I became interested in ILC. Dr. Rafeh Naqash: Well, thank you for sharing those personal insights and personal journey. I am sure it will inspire other trainees, fellows, and perhaps junior faculty in trying to find their niche. The path, as you mentioned, is not always straight; it often tends to be convoluted. And then finding an area that you are interested in, taking things forward, and being persistent is often what matters. Dr. Julia Foldi: Thank you so much for having me. It was great. Dr. Rafeh Naqash: It was great chatting with you. And thank you for listening to JCO Precision Oncology Conversations. Don't forget to give us a rating or review, and be sure to subscribe so you never miss an episode. You can find all ASCO shows at asco.org/podcasts. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.
You may have heard that a little dirt is good for kids. It helps them build up their immune systems, and sets them on a path to future health. But what kind of filth does the trick? Producer Kathleen Davis digs into the latest science on the benefits of exposing kids to the outdoors with microbiologist Jack Gilbert and pediatric epidemiologist Amber Fyfe-Johnson.Guests:Dr. Jack Gilbert is a microbiologist and professor at the Scripps Institution of Oceanography and in the department of pediatrics in UC San Diego School of Medicine.Dr. Amber Fyfe-Johnson is an associate professor and pediatric epidemiologist at Institute for Research and Education to Advance Community Health at Washington State University.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
Un fármaco contra la leucemia (Tenipósido) revela una nueva aplicación al comprobarse que activa la defensa innata del sistema inmune (proteína STING) y podría utilizarse en el contexto de la inmunoterapia frente al cáncer. Adrián Velázquez, catedrático de Bioquímica e investigador del BIFI de la Universidad de Zaragoza, ha participado en este hallazgo que publica la revista científica Frontiers in Immunology y lo cuenta en Ágora. Por otro lado, Clara Malo (I3A y Facultad de Veterinaria Unizar) expone su investigación sobre preservación de tejido ovárico. Alrededor del 30% de las niñas que superan un cáncer infantil tienen después grandes dificultades para ser madres. Estos problemas de fertilidad vienen derivados de los agresivos tratamientos que reciben para curarse. Por ello, el Instituto de Investigación en Ingeniería de Aragón y ASPANOA llevan a cabo un proyecto para mejorar la preservación del tejido ovárico de las niñas con cáncer.
Recorded October 31, 2025 In this episode of BioTalk Unzipped, Gregory Austin and Dr. Chad Briscoe sit down with Dr. Kate Neville, immunologist turned seasoned biotech patent attorney at Marshall, Gerstein & Borun, to unpack one of the most misunderstood and mission-critical areas of life sciences: intellectual property.If you are a biotech founder, scientist, executive, or investor, this conversation is essential listening.We explore what patent prosecution really means, when startups should begin thinking about IP protection, how “freedom to operate” can determine commercial viability, and how emerging AI tools are reshaping the patent landscape.Dr. Neville brings 25+ years of experience guiding university spin-outs, biotech startups, and global pharmaceutical companies through complex patent strategy. She has helped secure patents for FDA-approved drugs and offers a rare dual perspective as both scientist and attorney.In This Episode We Discuss:• The difference between patent prosecution and patent litigation• Why it is never too early for biotech startups to think about IP• The U.S. one-year grace period vs. Europe's stricter disclosure rules• What “Freedom to Operate” really means for commercialization• Antibody patents, CDR regions, and the doctrine of equivalents• How premature disclosure can impact global patent strategy• The real-world back-and-forth of patent office “office actions”• AI-assisted prior art search at the USPTO — opportunity or risk?• How funding cycles influence patent filing decisions• Women in biotech leadership and venture funding disparities• The most rewarding part of protecting life-changing therapiesWe also break down the USPTO's new AI pilot programs designed to modernize patent examination and discuss how artificial intelligence may impact biotech patenting over the next several years.Why This MattersIntellectual property is often the single most valuable asset in a biotech company.Strong IP strategy can unlock funding, partnerships, and market exclusivity.Weak or mistimed IP decisions can permanently limit global opportunity.For founders and scientists: timing, geography, and disclosure discipline matter more than most people realize.About Our GuestDr. Kate NevillePartner, Marshall, Gerstein & BorunPhD in Immunology, JDLinkedIn: https://www.linkedin.com/in/kate-neville-phd/Firm Bio: https://www.marshallip.com/katherine-l-neville-ph-d/Charity Highlight: Girls on the Run ChicagoAn organization building confidence and resilience in young girls through mentorship and athletic achievement.https://www.girlsontherun.org/HostsDr. Chad BriscoeBioanalytical Scientific Leaderhttps://www.linkedin.com/in/chadbriscoe/Gregory AustinDirector, Business Development | Bioanalysishttps://www.linkedin.com/in/gregoryaustin1/If you enjoyed this episode, subscribe to BioTalk Unzipped on Apple Podcasts, Spotify, or your preferred platform and share with a colleague in biotech, pharma, or life sciences innovation.
“I do not believe we should be testing to test. We have to know, is this test going to change management and is it going to make a difference,” says pediatric allergist-immunologist Dr. Zachary Rubin. His knack for providing that sort of straightforward guidance explains why Dr. Rubin has become a trusted voice on allergies, asthma, and vaccines for his millions of followers on social media platforms. It's also why we couldn't ask for a better guide for our discussion on the rise in allergies, asthma, and immune-related conditions in children, and how families can navigate the quickly evolving science and rampant misinformation in the space. On this episode of Raise the Line, we also preview Dr. Rubin's new book, All About Allergies, in which he breaks down dozens of conditions and diseases, offering clear explanations and practical treatment options for families. Join host Lindsey Smith for this super informative conversation in which Dr. Rubin shares his thoughts on a wide range of topics including: What's behind the rise in allergic and immune-related conditions.Tips for managing misinformation, myths and misunderstandings. How digital platforms can be leveraged to strengthen public health.How to build back public trust in medicine.Mentioned in this episode:All About Allergies bookBench to Bedside PodcastInstagramTikTokYouTube Channel If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast
In this episode of Conversations in Lung Cancer Research, host A/Prof Mel Moore interviews Dr. Megan Sanders, the Chief Executive Officer of TOGA. They discuss Megan's journey from working in vaccine formulation to earning a PhD in immunology, working in clinical trials, and eventually leading TOGA. They explore the challenges and achievements of TOGA, the importance of multidisciplinary engagement in lung cancer treatment, and the organisation's strategic plan for strengthening research and membership engagement. The conversation touches on the potential of clinical quality registries to improve patient care and highlights the ongoing effort to address the gaps in funding and equitable care for lung cancer patients.(00:00) Introduction and Acknowledgements(00:36) Meet Dr. Megan Sanders: From Science to Leadership(01:21) Journey from Academia to Clinical Trials(05:27) Challenges and Rewards in Clinical Trials(09:24) TOGA's Achievements and Multidisciplinary Approach(26:39) Future Directions and Strategic Plans(36:55) Conclusion and Final Thoughts Links: Dr Megan Sanders https://www.linkedin.com/in/megan-sanders-20130156/TOGA Strategic Plan: https://thoraciconcology.org.au/news/toga/toga-launches-new-strategic-plan-2025-2028-to-advance-thoracic-cancer-research-in-australasia/TOGA ASM 2026:https://thoraciconcology.org.au/events/toga-annual-scientific-meeting-2026/
We continue our tradition of interviewing the incoming president of the American College of Allergy, Asthma & Immunology to learn what is top of mind for the field and what it means for patients and families. Dr. Cherie Zachary joins us to share her personal journey into allergy and immunology as both a lifelong patient and clinician. She explains what the ACAAI does and why increasing representation in medicine is critical for improving allergy outcomes. The conversation also tackles the allergist shortage, how physicians are trained, and what is being done to expand fellowship opportunities and improve access to care. What we cover in our episode about Dr. Zachary & ACAAI What the ACAAI actually does for allergy care: How the College supports clinicians and provides patients with trusted, evidence-based education. How lived experience shapes leadership: How Dr. Zachary's own allergic diseases influenced her path into allergy and immunology. Why representation matters for allergy outcomes: How culturally responsive care and physician diversity improve trust and health outcomes. Why there are not enough allergists: How training bottlenecks contribute to long wait times and limited access to care. Historically Black Colleges and Universities (HBCUs): Her focus on expanding exposure to allergy through HBCUs and the ACAAI SPARK program. More resources about what we discussed American College of Allergy, Asthma, and Immunology Listen: Ep. 77: Food Allergy and Its Impact on the Black Community Listen: Ep. 108: Interview with Dr. James Tracy Listen: Ep. 66: Interview with Dr. Gailen D. Marshall, Jr. -- Made in partnership with The Allergy & Asthma Network. We thank the American College of Allergy, Asthma, and Immunology for their support of Allergy & Asthma Network and this podcast.
Today we're taking a closer look at dental implants and the key factors that influence their long-term success—from what patients can do to lower their risk of peri-implantitis, to whether CBCT imaging has become the new standard of care in implant dentistry. We'll also examine the role of systemic health, including the connection between bisphosphonate use and osteonecrosis of the jaw, as well as the latest insights on how antacids, particularly proton pump inhibitors, may affect implant outcomes. Our guest is Dr. Jon Suzuki, Professor of Microbiology and Immunology and of Periodontology and Oral Implantology at Temple University. A former Dean at the University of Pittsburgh, he has chaired the FDA Dental Products Panel, led the ADA Council on Scientific Affairs, and served on numerous NIH committees. A Diplomate of the American Board of Periodontology, he has published over 200 papers and a textbook, and continues to educate dentists all over the world. Thanks to our episode sponsors: EMS Dental - https://www.ems-dental.com/en-us Shofu Dental - https://www.shofu.com/en
Ahead of Pat Kenny's move to weekends at the beginning of March, we've delved into the archives to bring you some of the best pieces from his dozen-and-a-half years of mornings on Newstalk.The Christmas season brings with it lots of merrymaking and in spite of less drinking happening overall and the availability of many zero alcohol products, many of us will be getting drunk. And soon afterwards, many of us will regret it. Surely the answer is simple: to avoid a hangover, just drink less? Alas, that is easier said than done. Alcohol's inhibition-reducing effects can undermine the steeliest resolve.All to discuss with Professor Luke O Neill , Professor of Biochemistry at the school of Immunology, Trinity College. Join Pat every Saturday & Sunday morning from 10am, starting in March.Download the brand new GoLoud App in the Play Store & App Store right now! We have got you covered!
Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we delve into a series of insightful updates that highlight the dynamic and rapidly evolving nature of these sectors, driven by scientific advancements, regulatory shifts, and strategic industry maneuvers.Starting with Merck, which is strategically planning for a post-Keytruda era, projecting over $70 billion in annual opportunities over the next decade. With Keytruda's patent expiration looming in 2028, Merck is actively expanding its portfolio through acquisitions and partnerships, focusing on oncology and immunology. These areas have been significantly impacted by Keytruda's success, and Merck's proactive approach aims to sustain growth and innovation beyond its current flagship product. During their 2025 full-year earnings call, CEO Robert Davis emphasized their expansive pipeline, highlighting recent strategic deals as pivotal to Merck's robust pipeline—the broadest it has been in years—signaling long-term growth through diversified therapeutic areas and innovative drug candidates.The U.S. Food and Drug Administration (FDA) is making waves with its regulatory approach to CAR-T cell therapies for autoimmune diseases. This shift reflects an increasing recognition of the potential these therapies hold for transforming treatment paradigms for conditions like lupus and multiple sclerosis. By offering a more flexible regulatory framework, the FDA is encouraging innovation while maintaining a focus on patient safety.In other regulatory news, AstraZeneca faces a setback with the FDA's rejection of its subcutaneous version of Saphnelo for lupus. The decision underscores the challenges associated with developing more patient-friendly administration methods for biologics. However, AstraZeneca remains optimistic about achieving a quick turnaround in the approval process, which could enhance patient adherence by offering a self-administered alternative to intravenous infusions.Sanofi finds itself in the spotlight after CEO Paul Hudson was sanctioned by the UK's Prescription Medicines Code of Practice Authority for making overly ambitious claims about Pfizer's RSV vaccine. This incident illustrates the competitive nature of vaccine procurement and underscores the importance of accurate communication by pharmaceutical leaders.In Massachusetts, Thermo Fisher Scientific is reducing its workforce with the closure of its Franklin site, impacting around 200 employees. This move is part of broader strategic realignments within the industry aimed at optimizing operations and focusing resources on high-growth areas.Acadia Pharmaceuticals faces potential rejection by the European Union for its drug trofinetide intended for Rett syndrome. This highlights ongoing challenges in gaining approval for treatments targeting rare diseases, despite their significant unmet needs.Meanwhile, GSK plans to lay off up to 350 R&D workers across the U.S. and UK as part of efforts to streamline operations and focus on core therapeutic areas. Such layoffs reflect broader industry trends toward consolidation and efficiency amid rising R&D costs.On a more promising note, Pfizer's GLP-1 receptor agonist has demonstrated significant results in a Phase 2b trial for weight loss, validating their substantial investment in this area. The drug's potential to offer competitive weight loss results with monthly dosing positions it as a strong contender in the obesity treatment market. Additionally, Pfizer continues to accelerate its efforts in obesity treatment with promising mid-stage trial results for PF-3944, showing up to a 12.3% weight loss at 28 weeks. This suggests Pfizer is keen on expanding its presence in obesity management through strategic clinical development as competition within this therapeutic area intensifies.The U.S. Department of Health and HumanSupport the show
In this episode, we review the high-yield topic of Chronic mucocutaneous Candidiasis from the Immunology section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
In this episode, we review the high-yield topic of Recombinant Cytokines from the Immunology section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
Republicans are standing up to the White House to protect health, science and space research funding from draconian cuts. All to discuss with Luke O'Neill, Professor of Biochemistry and Immunology, Trinity College Dublin.
Dr. Jessica Rose, PhD, MSc, BSc, is a Senior Fellow specializing in Computational Biology from Canada. She holds a Bachelor's Degree in applied mathematics and a master's degree in Immunology from Memorial University of Newfoundland, and a PhD in Computational Biology from Bar Ilan University. Dr. Rose has completed two post-doctoral degrees in Molecular Biology from the Hebrew University of Jerusalem, and in Biochemistry from the Technion Institute of Technology. She is best known for her contributions to public health and safety related to the COVID-19 injectable products, and her analyses of pharmacovigilance databases like VAERS. In this episode, Drs. Brian and Jessica talk about… (00:00) Intro (04:57) Dr. Jessica's upbringing, personality, and scientific pursuits (09:41) Covid vaccines, natural immunity, and bodily autonomy of individuals (19:50) The research of Kevin McKernan on DNA in vials of COVID-19 vaccines (27:39) The composition and production of Covid mRNA vaccines (33:04) National health regulation agencies and Covid vaccine DNA contamination (35:54) Lipid nanoparticles in mRNA vaccines and how they impact human health (44:22) Vaccine injuries due to spike protein proliferation and how the spike protein ruins the human immune system (54:38) Spike protein detox therapies (01:01:12) Fascia release (01:03:07) Cholesterol, gal bladder health, and nutrition (01:07:54) Fasting, autophogy, and the microbiome (01:11:33) Peer review and post-peer review attacks on valid research (01:21:53) Outro For more information, please see the links below. Thank you for listening! Links: Resources Mentioned in this Episode: Jules Horn (Fascia Release): https://www.youtube.com/@Jules_horn Science Guardians (post-peer review group): https://x.com/SciGuardians Dr. Jessica Rose: Research: https://www.researchgate.net/profile/Jessica-Rose-24 Why does DNA remain in vials of COVID-19 mRNA Shots?: https://rumble.com/v74rdvs-why-does-dna-remain-in-vials-of-covid-19-mrna-shots.html What Jessica Rose Knows: Dr. Jessica Rose on DarkHorse: https://rumble.com/v5q0zl8-what-jessica-rose-knows-dr.-jessica-rose-on-darkhorse.html Dr. Brian Lenzkes: Arizona Metabolic Health: https://arizonametabolichealth.com/ Low Carb MD Podcast: https://www.lowcarbmd.com/ HLTH Code: HLTH Code Promo Code: METHEALTH • • HLTH Code Website: https://gethlth.com
Dr. Gillis updates us all with fibromyalgia as no longer belonging in Rheumatology but Immunology. His research developed a blood test to detect defective white blood cells as the source and causation of the illness. The blood test website is www.fm1test.com & the compound that results in eliminating symptoms is www.imbxx.com a 30 day supply to provide a working solution for those who suffer from the illness.
In this episode, we review the high-yield topic of MHC Deficiency from the Immunology section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
Synopsis: Fresh from the JPM 2026 in San Francisco, Alok Tayi welcomes Johan Luthman, Executive Vice President of R&D at Lundbeck, for a sweeping, deeply personal conversation on the future of neuroscience drug development. From his early days as a Swedish clinician-scientist to leading breakthrough Alzheimer's programs and rebuilding Lundbeck's pipeline from the ground up, Johan shares the pivotal moments—and phone calls—that shaped a 30-year career across AstraZeneca, Merck, Serono, and now Denmark's neuroscience powerhouse. The discussion dives into Lundbeck's bold strategic reset: letting biology lead, de-risking early in patients, embracing rare disease and sleep medicine, and making disciplined bets on monoclonal antibodies, migraine prevention, epilepsy, and neuroendocrine disorders. Johan explains how the company shifted capital toward innovation, rebuilt its portfolio through targeted acquisitions, and built one of the most advanced neuroscience pipelines in pharma today. In one of the episode's most powerful moments, Johan opens up about his personal motivation—caring for family members with Alzheimer's and dedicating his career to diseases of the brain. From AI-driven R&D productivity and adaptive trials to Denmark's unique foundation-owned pharma model, this conversation is a masterclass in scientific rigor, decision-making under uncertainty, and keeping patients at the center of everything. Biography: In 1991, Johan Luthman began his career in the pharmaceutical industry in Astra, later AstraZeneca. In 2005, Johan joined Serono as Head of Neuroscience & Immunology Research, and subsequently, in MerckSerono, as Therapy Area Head, Neurology & Immunology. In 2009, he became CEO of biotech start-up GeNeuro. In late 2009, Johan joined Merck as VP & Franchise Integrator for Neuroscience and Ophthalmology. In 2014, he came to Eisai where he was Senior Vice President and Head of Clinical Development. Johan joined Lundbeck as Executive Vice President, R&D in March 2019. Johan is a Swedish national and is trained as a Doctor of Dental Sciences from the Karolinska Institute, Sweden. He also holds a PhD in Neurobiology and Histology as well as an Associate Professor title from the Karolinska Institute, Sweden. Johan is a Member of the Board of Directors of Brain+.
In episode 66 of Going anti-Viral, Dr Nicolas Chomont joins host Dr Michael Saag to provide a preview of the 2026 Conference on Retroviruses and Opportunistic Infections (CROI). Dr Chomont is Chair of the Scientific Program Committee for CROI 2026 and is a Professor in the Department of Microbiology, Infectious Diseases, and Immunology at the Université de Montréal and a researcher at the CHUM Research Centre. Dr Chomont discusses CROI 2026, highlighting its significance in advancing HIV research and treatment. He emphasizes the importance of community engagement, the support for new investigators, and ongoing research for an HIV cure. The discussion provides the overall themes of the abstracts accepted for CROI 2026 as well as the plenary sessions, symposia, and the impact of funding cuts on research and treatment. Dr Chomont expresses optimism about the future of HIV research and the collaborative spirit of the conference.0:00 – Introduction3:19 – Plenary sessions overview5:41 – Interactive symposia and themed discussion sessions8:09 – Themes of the accepted abstracts 11:09 – Support for new researchers15:25 – Research addressing a cure for HIV 18:21 – Community and collaboration at CROI20:55 – Closing remarks Register for virtual or in-person attendance at CROI 2026: https://www.croiconference.org/ __________________________________________________Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections. Going anti-Viral's host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.Follow Going anti-Viral on: Apple Podcasts YouTubeXFacebookInstagram...
Guest: Dr. Rafi Ahmed is a Professor in the Department of Microbiology and Immunology and the Director of the Emory Vaccine Center at Emory University. He talks about his early work on memory T cells and its applications in autoimmune diseases and cancer. Featured Products and Resources: Register now for IMMUNOLOGY2026! Request Your Free EasySep Sample and Enter for a Chance to Win Prizes Worth Up to $3,000. The Immunology Round Up CAR T Therapy for Hemolytic Anemia: CD19 CAR T cells resulted in sustained remission in patients with multirefractory autoimmune hemolytic anemia. (3:05) How Epstein-Barr Virus and Genetics Drive Multiple Sclerosis: A new study provides a new mechanistic link for how the environmental and genetic risk factors may contribute jointly to multiple sclerosis. (8:30) Autoantigens in Multiple Sclerosis: EBNA1 CD4+ T cells can target the multiple sclerosis autoantigen anoctamin-2, establishing a link between Epstein-Barr infection and neuroinflammation. (18:45) Microbiota-Induced T Cell Plasticity: Molecular mimicry between a gut commensal and a tumor antigen can boost the efficacy of immune checkpoint blockade therapy and restrain tumor growth. (26:00) Subscribe to our newsletter! Never miss updates about new episodes. Subscribe
In this episode, we review the high-yield topic of Structure and Function of MHC from the Immunology section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
This episode features Chris Breitigan reading 3 immunology questions from our online qbank. Dr. Ted O'Connell Ted O'Connell, MD, FAAFP, is the Director of Medical Education for Kaiser Permanente Northern California. He is also an Associate Clinical Professor in the Department of Family and Community Medicine at the UC San Francisco School of Medicine. Ted has authored over 20 medical textbooks, edited 10 additional textbooks, and has written over 900 textbook chapters as well as articles in peer-reviewed medical journals. Ted has been involved in medical education for over two decades, serving as Founding Program Director at the Kaiser Permanente Napa-Solano family medicine residency program for 10 years and the Program Director at the Kaiser Permanente Woodland Hills residency program for 7 years. Ted is Editor-In-Chief of Elsevier's Clinical Key Student, an international medical education platform. Ted is also the award-winning host of several podcasts. Dr. Raj Dasgupta Dr. Raj is a quadruple board-certified physician and associate professor at the University of Southern California. He was a co-host on the TNT series Chasing the Cure with Ann Curry, a regular on the TV Show The Doctors for the past 7 seasons and has a weekly medical segment on ABC news Los Angeles. Our Websites MedPrepToGo Website BookRevision.com Dr. O'Connell's Website Dr. Dasgupta's Website Other Podcasts USMLE Step 1 Questions USMLE Step 1 Ad-Free Bundle Crush Step 1 Step 2 Secrets Beyond the Pearls The Dr. Raj Podcast Beyond the Pearls Premium USMLE Step 3 Review Legal/Credits All information is for entertainment and educational purposes only and is not intended as medical advice. Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode, we review the high-yield topic of Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) from the Immunology section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
In this episode, we review the high-yield topic of Ataxia-Telangiectasia from the Immunology section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
In this episode, we review the high-yield topic of Selective IGA deficiency from the Immunology section.Follow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets
About this episode: Nothing can make your skin crawl quite like the mention of lice or bed bugs, especially if you're the parent of young children. The good news: though these blood-sucking pests are a nuisance, they pose limited risk to human health. In this episode: Parasitologist Conor McMeniman explains why infestations start, who's susceptible, and how to get these pests out of your hair—literally. Guest: Conor McMeniman, PhD, is an associate professor of Molecular Microbiology and Immunology and faculty at the Johns Hopkins Malaria Research Institute. Host: Lindsay Smith Rogers, MA, is the producer of the Public Health On Call podcast, an editor for Expert Insights, and the director of content strategy for the Johns Hopkins Bloomberg School of Public Health. Show links and related content: No-Panic Guide to Head Lice Treatment—Johns Hopkins Medicine Bed Bugs: Get Them Out and Keep Them Out—U.S. Environmental Protection Agency Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @PublicHealthPod on Bluesky @PublicHealthPod on Instagram @JohnsHopkinsSPH on Facebook @PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.
As the climate has changed, Austin's allergy seasons have morphed into more of a year-round suffer fest, do-si-do-ing smoothly from cedar or juniper, to grass, then ragweed, and oak. And right now, we're in the thick of cedar season, which is absolutely loving this weather. Host Nikki DaVaughn, a victim of allergies herself, is joined today by Dr. Neha Reshamwala, doctor and founder of Frontier Allergy, Asthma & Immunology, to talk about why cedar is thriving this year, if it's actually getting worse from year to year, and how to treat cedar fever. Want some more Austin news? Then make sure to sign up for our Hey Austin newsletter. And don't forget– you can support this show and get great perks by becoming a City Cast Austin Neighbor at membership.citycast.fm Follow us @citycastaustin You can also text us or leave a voicemail. Interested in advertising with City Cast? Find more info HERE Learn more about the sponsors of this January 21st episode: Jeremiah Program Austin
Support the Institute today. https://givenow.nova.edu/the-institute-for-neuro-immune-medicine-inim-2025 In this episode, Haylie Pomroy speaks with Dr. Theoharis Theoharides about multiple chemical sensitivity (MCS). He explains the immunological responses occurring within the body, the symptoms and daily experiences reported by patients, and the connection between MCS and mast cell activation. Dr. Theoharides also offers expert guidance on managing MCS, explains the diagnostic codes associated with mast cell activation, and emphasizes why blocking mast cells is critical to the healing process. He further discusses how stress can trigger mast cell reactivation, the role of vitamin D3, and why measuring chemical exposures and mycotoxins does not always indicate the absence of ongoing immune reactivation. Dr. Theoharis Theoharides is a Professor, Vice Chair of Clinical Immunology, and Director at the Institute for Neuro-Immune Medicine-Clearwater, an Adjunct Professor of Immunology at Tufts School of Medicine, where he was a Professor of Pharmacology and Internal Medicine, and also the Director of Molecular Immunopharmacology & Drug Discovery, and Clinical Pharmacologist at the Massachusetts Drug Formulary Commission (1983-2022). He received his BA, MS, MPhil, PhD, and MD degrees and the Winternitz Price in Pathology from Yale University and received a Certificate in Global Leadership from Tufts Fletcher School of Law and Diplomacy and a Fellowship at Harvard Kennedy School of Government. He trained in internal medicine at New England Medical Center, which awarded him the Oliver Smith Award, "recognizing excellence, compassion, and service." Dr. Theoharides has 485 publications (46,491 citations; h-index 106), placing him in the world's top 2% of most cited authors, and he was rated the worldwide expert on mast cells by Expertscape. He was inducted into the Alpha Omega Alpha National Medical Honor Society, the Rare Diseases Hall of Fame, and the World Academy of Sciences. Website: https://www.drtheoharides.com LinkedIn: linkedin.com/in/theoharis-theoharides-ms-phd-md-faaaai-67123735 Instagram: https://www.instagram.com/dr.theoharides/ Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet. Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com Instagram: https://www.instagram.com/hayliepomroy Facebook: https://www.facebook.com/hayliepomroy YouTube: https://www.youtube.com/@hayliepomroy/videos LinkedIn: https://www.linkedin.com/in/hayliepomroy/ X: https://x.com/hayliepomroy Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d This podcast is brought to you by the Institute for Neuro-Immune Medicine. Learn more about us here. Website: https://www.nova.edu/nim/ Facebook: https://www.facebook.com/InstituteForNeuroImmuneMedicine Instagram: https://www.instagram.com/NSU_INIM/ Twitter: https://www.twitter.com/NSU_INIM
On this episode Lara and Vyanka talk to Professor Alex Richter from the University of Birmingham all about Precision Diagnostics in Immunology. This is ImmunoTea: Your Immunology Podcast, presented by Dr Lara Dungan and Dr Vyanka Redenbaugh. This is the show where we tell you all about the most exciting research going on in the world of immunology. So grab a cup of tea, sit down and relax and we'll fill you in. Contact us at ImmunoTeaPodcast@gmail.com or @ImmunoTea on twitter. Hosted on Acast. See acast.com/privacy for more information.
In this episode we're diving into the fascinating world where science, scalp health, and the microbiome meet beauty and wellbeing. Hair loss isn't just about vanity—it's a window into what's happening beneath the surface. Our guest is Dr. Echeverry and in this episode we will speak to what really drives hair loss, how the microbiome and immune system influence the follicle, and why restoring balance—not just applying treatments—is key to long-term hair and scalp health. Dr. Andrea Echeverry is a biologist with a Ph.D. in Microbiology and Immunology from the University of Miami and a B.Sc. in Microbiology and Biotechnology from Florida Atlantic University. After pioneering neonatal mouse models for intestinal infection research, she shifted her focus to the intersection of the gut, skin, and scalp microbiome—especially its role in chronic inflammation and hair loss. For over 14 years, Dr. Echeverry has collaborated with barbers, dermatologists, and hair transplant surgeons across Florida, Georgia, and Puerto Rico to highlight the microbiome's vital role in scalp and hair health. Combining trichology, microbial ecology, and micropigmentation, she helps clients restore both hair and confidence. A passionate educator and advocate, she promotes hair loss prevention among young adults and is producing a bilingual web series sharing real hair loss journeys. Dr. Echeverry also serves on the Executive and Educational Boards of the Association of Professional Trichologists (APT), where she is the immediate past President and Treasurer. Learning Points: What drives hair loss How the microbiome and immune system influence the hair follicle Why restoring balance—not just applying treatments—is key to long-term hair and scalp health. Social Media: Website: https://www.drandreaecheverry.com Instagram: http://www.instagram.com/drandreaecheverry Linkedin: http://linkedin.com/in/drandreaecheverry
Why You Should Listen: In this episode, you will discover how addressing parasites and dental issues can unlock better health and why real healing is rarely an Accidental Cure. About My Guest: My guest for this episode is Dr. Simon Yu. Simon Yu, MD combines internal medicine with integrative medicine at Prevention and Healing, Inc., in St. Louis, MO. As an HMO regional medical director, he saw the limits of a medication-management approach to patients with complex chronic illness. He studied integrative and biological medicine, took 300 hours of medical acupuncture training, and researched dental, fungal, and parasite problems. He served as a medical officer in the U.S. Army Reserve for 25 years, retiring as a full colonel. Dr. Yu lectures in the US and abroad. He offers Acupuncture Meridian Assessment (AMA) Training to help detect problems for doctors and dentists in St. Louis and in Germany. He has an MD from the University of Missouri School of Medicine, has an MS in Immunology, is certified by the American Board of Internal Medicine, a member of American College of Physicians, and is on the advisory board of the International College of Integrative Medicine. Key Takeaways: Where does Artificial Intelligence fit in addressing complex, chronic illnesses? What are the more common patterns of meridian dysregulation observed? How are most parasites acquired? Are parasites always bad for the body? What are the more common medications used to address parasites? Does mold in the external environment impact parasite treatment or dental interventions? Are all parasites that impact health physical? How is the treatment of fungal issues approached? Should patients test their home for mold? What types of dental issues are most commonly impacting patients? How does testing for the DNA of oral pathogens inform treatment? What long-term oral hygiene strategies may be helpful? Are implants appropriate after an extraction? How has treating complex patients changed with COVID? Is spike protein detoxification now part of the healing approach? Do EMFs negatively impact health? Are conditions such as Ehlers-Danlos Syndrome and Morgellons approached differently? What are some top detoxification strategies? Is "autoimmunity" the result of chronic infections? What is the best approach for optimizing the microbiome? What are some of the emerging treatment interventions from SOZO Brain Clinic? Connect With My Guest: PreventionAndHealing.com Related Resources: Book - Accidental Cure 3: AI vs. Ancient Intelligence Interview Date: January 7, 2026 Transcript: To review a transcript of this show, visit https://BetterHealthGuy.com/Episode227. Support the Show: To support the show and Buy Me a Coffee, visit https://betterhealthguy.link/BuyMeACoffee. Additional Information: To learn more, visit https://BetterHealthGuy.com. Follow Me on Social Media: Facebook - https://facebook.com/betterhealthguy Instagram - https://instagram.com/betterhealthguy X - https://twitter.com/betterhealthguy TikTok - https://tiktok.com/@betterhealthguy Disclaimer: The content of this show is for informational purposes only and is not intended to diagnose, treat, or cure any illness or medical condition. Nothing in today's discussion is meant to serve as medical advice or as information to facilitate self-treatment. As always, please discuss any potential health-related decisions with your own personal medical authority.
About this episode: Flu is surging in states across the country, breaking a 25-year record for flu-related doctor visits. In this episode: the new strain of influenza A that's driving cases, why getting a flu shot can still protect you, and how antivirals can help if you do get sick. Guest: Andrew Pekosz, PhD, is a virologist at the Johns Hopkins Bloomberg School of Public Health with appointments in Molecular Microbiology and Immunology and Environmental Health and Engineering. Host: Stephanie Desmon, MA, is a former journalist, author, and the director of public relations and communications for the Johns Hopkins Center for Communication Programs. Show links and related content: Doctors still recommend flu shot despite sneaky new strain—Politifact US Flu Cases Show No Signs of Letting Up—Bloomberg Flu reaches highest level in the US in 25 years—CNN How Bad Will This Winter Be for Flu, COVID, RSV, and Measles?—Johns Hopkins Bloomberg School of Public Health Transcript information: Looking for episode transcripts? Open our podcast on the Apple Podcasts app (desktop or mobile) or the Spotify mobile app to access an auto-generated transcript of any episode. Closed captioning is also available for every episode on our YouTube channel. Contact us: Have a question about something you heard? Looking for a transcript? Want to suggest a topic or guest? Contact us via email or visit our website. Follow us: @PublicHealthPod on Bluesky @PublicHealthPod on Instagram @JohnsHopkinsSPH on Facebook @PublicHealthOnCall on YouTube Here's our RSS feed Note: These podcasts are a conversation between the participants, and do not represent the position of Johns Hopkins University.
The USDA and HHS just released new Dietary Guidelines for Americans. We dig into the new guidelines with Dr. Leigh Frame, our favorite nutrition scientist, co-host of the pod, and co-director of the Frame-Corr Lab here at George Washington University School of Medicine & Health Sciences. An Associate Professor in the departments of Clinical Research & Leadership and Physician Assistant Studies, Leigh combines nutrition and immunity through translational research, leveraging extensive experience in biomedical research and education. Dr. Frame earned her PhD in Human Nutrition and MHS in Immunology from the Johns Hopkins Bloomberg School of Public Health and graduated with Distinction in Biochemistry from Mary Baldwin College. An expert on Integrative Medicine and the gut microbiome, she's also the Executive Director of the GW Office of Integrative Medicine & Health. ◘ Related Links: New Food Guidelines for Americans, https://realfood.gov/; Harvard Healthy Eating Plate, https://nutritionsource.hsph.harvard.edu/healthy-eating-plate/; Dr. Frame's Nutrition Guide, https://rwc.smhs.gwu.edu/nutrition-guide; Canada's Food Guide, https://food-guide.canada.ca/en/ ◘ Transcript bit.ly/3JoA2mz ◘ This podcast features the song “Follow Your Dreams” (freemusicarchive.org/music/Scott_Ho…ur_Dreams_1918) by Scott Holmes, available under a Creative Commons Attribution-Noncommercial (01https://creativecommons.org/licenses/by-nc/4.0/) license. ◘ Disclaimer: The content and information shared in GW Integrative Medicine is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in GW Integrative Medicine represent the opinions of the host(s) and their guest(s). For medical advice, diagnosis, and/or treatment, please consult a medical professional.
Kate Haviland, former CEO of Blueprint Medicines, on how the company transitioned to a precision immunology company and was acquired by Sanofi for $9.5 billion.
C'est un terme médical réel, bien que peu connu du grand public. Il désigne un ensemble de réactions allergiques ou irritatives qui apparaissent chez certaines personnes lorsqu'un sapin — naturel ou artificiel — est installé à la maison pendant les fêtes.Voici ce que recouvre précisément ce syndrome :1. Allergies liées aux sapins naturelsLes sapins fraîchement coupés peuvent provoquer une réaction chez les personnes sensibles, non pas à l'arbre lui-même, mais à ce qu'il transporte :• Moisissures microscopiquesLes sapins, lorsqu'ils poussent, accumulent sur leurs aiguilles et leur écorce des spores de moisissures (comme Alternaria ou Cladosporium).En intérieur, avec la chaleur, ces spores se dispersent et peuvent déclencher :touxrhinitesinusitecrises d'asthmefatigue ou maux de têteUne étude de la American College of Allergy, Asthma & Immunology a montré que la concentration de spores dans une maison peut être multipliée par 6 dans les jours suivant l'installation d'un sapin naturel.• Résine et composés odorantsCertaines personnes réagissent aux terpènes (les molécules responsables de l'odeur de “forêt”).Cela peut entraîner :irritations des yeuxdémangeaisonspetite douleur dans la gorgeeczéma de contact2. Allergies liées aux sapins artificielsContrairement à l'idée reçue, ils ne sont pas toujours mieux tolérés.Les sapins artificiels peuvent accumuler :poussièreacariensmoisissures (s'ils ont été stockés dans un endroit humide)L'ouverture du carton et l'installation du sapin peuvent alors provoquer des symptômes semblables à une allergie.3. Pourquoi parle-t-on de “syndrome” ?Le nom vient du fait que beaucoup de personnes présentent chaque année, à la même période, des symptômes respiratoires qui disparaissent… quand on retire le sapin.C'est donc une forme d'allergie saisonnière, mais liée à un objet domestique plutôt qu'à la nature extérieure.4. Qui est le plus concerné ?personnes asthmatiquespersonnes allergiques aux moisissuresenfants sensiblespersonnes souffrant de rhinites allergiques5. Comment l'éviter ?Rincer brièvement un sapin naturel avant installation.Le laisser sécher à l'extérieur.Nettoyer un sapin artificiel avant usage.Aérer largement la pièce chaque jour.Éviter de garder le sapin plus de 2 à 3 semaines. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Dr. Hoffman continues his conversation with Dr. Heather Zwickey, Vice President of Research and Academic Excellence, Provost, and Professor of Immunology at the National University of Natural Medicine (NUNM).
Innovative Approaches to Parkinson's Disease with Dr. Heather Zwickey, Vice President of Research and Academic Excellence, Provost, and Professor of Immunology at the National University of Natural Medicine (NUNM), and author of "Eating Better for Parkinson's: A Nutritional Starter Guide." She delves into innovative treatments for Parkinson's disease, including the role of diet, particularly a ketogenic diet, and the impact of the gut microbiome. Dr. Zwickey shares her inspiration from NBA player Brian Grant's experience with Parkinson's and discusses her small study on the feasibility of a ketogenic diet, showing promising results. She also details other potential treatments like supplements, exercise, particularly boxing and dancing, environmental factors, and even cannabis. Dr. Zwickey highlights the importance of personalized approaches due to varying individual responses to treatments.
In the Real Science Exchange Legacy Series, we celebrate the pioneers who have shaped the dairy industry. In this episode, we honor Dr. Don Beitz, a distinguished professor at Iowa State University. At the 2025 ADSA Annual Meeting, a symposium was held titled “Donald C. Beitz Recognition Symposium: 50-Plus Years of Dairy Science Research.” The guests on this episode, all former graduate students of Dr. Beitz, were speakers at the event. Join us as we explore Dr. Beitz's contributions and enduring impact on our industry. Panelists introduce themselves and how they met Dr. Beitz. Tricky MS and PhD exam questions are also shared. Panelists emphasize Dr. Beitz's love for biochemistry, teaching, and collaboration. (1:17)Dr. Beitz shares about his early life, academic career, and family. (11:45)Dr. Goff's symposium presentation focused on Dr. Beitz and colleagues' contribution to our understanding of transition cow hypocalcemia. He talks about studies on low calcium diets, investigating the metabolic pathways of vitamin D, and low phosphorus diets. Dr. Beitz also studied the impact of vitamin D on meat tenderness. (22:37)Dr. Nelson's presentation detailed the advances in understanding bovine immunology from the work of Don Beitz and his colleagues. From the milk fever vitamin D research, it was also discovered that vitamin D had an impact on the immune system, which led to further work with vitamin A and immunity as well. Dr. Beitz also had students investigate calf growth rate influence on immune system development as well as Johne's disease. (27:22)Dr. Drackley focused on Dr. Beitz's work in understanding fatty liver and ketosis. The transition period was of interest to Dr. Beitz, which is reflected not only in his work in hypocalcemia, but also the lipid and carbohydrate metabolism of ketosis. Dr. Beitz and his colleague, Dr. Young, developed a successful ketosis model using a slight feed restriction and supplementing a ketone body precursor, which was used to investigate ketosis and fatty liver. (30:25)Dr. VandeHaar spoke about Dr. Beitz's passion for research and teaching in dairy science, biochemistry, and life. He emphasized the depth and breadth of Dr. Beitz's work and teaching. He shared that Dr. Beitz has served as major professor for around 107 graduate students and has taught biochemistry to over 16,000 students. (35:02)The panelists share stories about Dr. Beitz's humility, care and support for students, and the many different professional societies he has been involved in over his career. (38:39)Panelists share their take-home thoughts. (42:56)Please subscribe and share with your industry friends to invite more people to join us at the Real Science Exchange virtual pub table. If you want one of our Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll mail you a shirt.
As we all learned in 2020, getting ahead of the next major pandemic is a matter of global concern. For the Coalition for Epidemic Preparedness Innovations, or CEPI (cepi.net), it is their reason for existing. Joining me for this conversation are Valentina Bernasconi, Head of Laboratory Science for CEPI, and Marie-Eve Poupart, Lead Scientist In Charles River's Immunology department. Together we discuss CEPI's progress so far, how Charles River is contributing to the cause, and how we can plan for the unknown Disease X while simultaneously handling current outbreaks of deadly diseases like Ebola, Marburg, Nipah virus, Lassa Fever, and chikungunya.
Today, I'm joined by Dr. Maeve O'Connor, a board-certified allergist and immunologist practicing in Charlotte, North Carolina. Dr. O'Connor's training reflects both rigor and range. She completed dual undergraduate degrees at the University of South Carolina Honors College with a Bachelor of Science in Biology and a Bachelor of Arts in Spanish before earning her medical degree at the University of South Carolina School of Medicine. She then completed her internship and residency at the University of Texas and its affiliated hospitals in Houston, where she served as Chief Medical Resident. Her subspecialty training in Allergy and Immunology was completed at the National Jewish Medical and Research Center in Denver consistently ranked the number one respiratory hospital in the United States where she developed deep expertise in asthma, allergic disease, and immune dysregulation. She further expanded her clinical lens through fellowship training in Integrative Medicine at the University of Arizona from 2013 to 2015. Clinically, Dr. O'Connor works at the intersection of pediatrics, immunology, and real family life where eczema isn't just a rash, food reactions aren't just labels, and immune symptoms rarely fit neatly into algorithmic boxes. Her work emphasizes careful diagnosis, evidence-based treatment, and avoiding both over-medicalization and missed pathology. In a time when allergy medicine is often reduced to test results and avoidance lists, Dr. O'Connor brings a grounded, thoughtful approach helping families and clinicians distinguish what's truly allergic, what's inflammatory, what's developmental, and what's simply noise. Today, we'll explore how allergic disease actually presents in children, why mislabeling is so common, how early immune signals shape long-term health, and how pediatricians and specialists can collaborate more effectively without fear-based medicine. This is a conversation about immune literacy, clinical nuance, and doing better for children in a world where their immune systems are under increasing pressure. I'm excited to welcome Dr. Maeve O'Connor. Dr. M
Support the Institute today: https://givenow.nova.edu/the-institute-for-neuro-immune-medicine-inim-2025 In this episode, Dr. Matthew Halpert and Justin Taylor Hughes join Haylie Pomroy to discuss how immunotherapy can play a critical role in cancer treatment, particularly for patients who may not qualify for clinical trials. Dr. Halpert outlines the clinical process used to support and treat patients, provides an in-depth explanation of immunotherapy and its role in targeting cancer, and discusses the concept of correcting biological dysfunction through biological intervention. Justin shares his personal cancer journey, from exploring multiple treatment modalities to ultimately choosing a holistic and metabolic approach to his diagnosis. He also reflects on his experience with immunotherapy and the importance of spiritual and emotional support for himself and others navigating cancer. Dr. Matthew Halpert, a PhD graduate in Microbiology and Immunology from the University of Alabama at Birmingham (UAB), spent 10 years at Baylor College of Medicine as a leading Cancer Immunologist. His groundbreaking work in cancer immunotherapy has been widely published and cited over 450 times. Dr. Halpert founded Diakonos Oncology, pioneering Dendritic Cell Treatment, which is currently in FDA clinical trials, including a "Fast Track" Glioblastoma trial. In 2021, he established the Immunocine Cancer Center to provide immediate access to this innovative treatment for patients ineligible for trials. Instagram: https://instagram.com/matthalpertphd https://instagram.com/immunocine Facebook - https://www.facebook.com/people/Matt-Halpert/100079347564008/ https://www.facebook.com/Immunocine X- https://x.com/Matthalpertphd https://x.com/ImmunocineCare LinkedIn: https://www.linkedin.com/in/matthew-halpert-b4695174/ https://www.linkedin.com/company/immunocine/ Website: https://immunocine.com Justin Taylor Hughes, born in San Angelo and raised in Bulverde, Texas, is a cancer survivor, author, businessman, and founder of The United Creed, LLC. Diagnosed with cancer during the pandemic, Justin and his wife, Berphy, were supported by a diverse community and are dedicated to promoting unity in America through the principle of "Be Golden." Get Justin's book, "Be Golden" here. https://www.amazon.com/Be-Golden-Unity-Justin-Hughes-ebook/dp/B0CMJ85JB5 Learn more about the United Creed: Website: https://theunitedcreed.com/ Facebook: https://web.facebook.com/unitedcreed?_rdc=1&_rdr X: https://x.com/theunitedcreed Instagram: https://www.instagram.com/united_creed/ LinkedIn: https://www.linkedin.com/company/the-united-creed/ Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet. Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com Instagram: https://www.instagram.com/hayliepomroy Facebook: https://www.facebook.com/hayliepomroy YouTube: https://www.youtube.com/@hayliepomroy/videos LinkedIn: https://www.linkedin.com/in/hayliepomroy/ X: https://x.com/hayliepomroy Enjoy our show? Please leave us a 5-star review on the following platforms so we can bring hope and help to others. Apple Podcasts: https://podcasts.apple.com/us/podcast/hope-and-help-for-fatigue-chronic-illness/id1724900423 Spotify: https://open.spotify.com/show/154isuc02GnkPEPlWfdXMT Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d Enjoy our show? Please leave us a 5-star review on the following platforms so we can bring hope and help to others. Apple Podcasts: https://podcasts.apple.com/us/podcast/hope-and-help-for-fatigue-chronic-illness/id1724900423 Spotify: https://open.spotify.com/show/154isuc02GnkPEPlWfdXMT Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d This podcast is brought to you by the Institute for Neuro-Immune Medicine. Learn more about us here. Website: https://www.nova.edu/nim/ Facebook: https://www.facebook.com/InstituteForNeuroImmuneMedicine Instagram: https://www.instagram.com/NSU_INIM/ Twitter: https://www.twitter.com/NSU_INIM
Support the Institute today: https://givenow.nova.edu/the-institute-for-neuro-immune-medicine-inim-2025 In this episode, Haylie Pomroy speaks with Dr. Theoharis Theoharides about the scientific foundations of brain fog. Together, they clarify its definition, physiological mechanisms, and how it presents across various illnesses and cognitive disorders. Dr. Theoharides further examines the relationship between brain fog and inflammation, explains how viral infections can contribute to the development of chronic illness, and discusses the role of microglia in neuroinflammation. He also reviews supplements that may help inhibit microglial activation, explains alpha-gal syndrome, and outlines relevant laboratory testing that can assist individuals experiencing brain fog in gaining clearer insight into their current health status. Dr. Theoharis Theoharides is a Professor, Vice Chair of Clinical Immunology, and Director at the Institute for Neuro-Immune Medicine-Clearwater, an Adjunct Professor of Immunology at Tufts School of Medicine, where he was a Professor of Pharmacology and Internal Medicine, and also the Director of Molecular Immunopharmacology & Drug Discovery, and Clinical Pharmacologist at the Massachusetts Drug Formulary Commission (1983-2022). He received his BA, MS, MPhil, PhD, and MD degrees and the Winternitz Price in Pathology from Yale University and received a Certificate in Global Leadership from Tufts Fletcher School of Law and Diplomacy and a Fellowship at Harvard Kennedy School of Government. He trained in internal medicine at New England Medical Center, which awarded him the Oliver Smith Award, "recognizing excellence, compassion, and service." Dr. Theoharides has 485 publications (46,491 citations; h-index 106), placing him in the world's top 2% of most cited authors, and he was rated the worldwide expert on mast cells by Expertscape. He was inducted into the Alpha Omega Alpha National Medical Honor Society, the Rare Diseases Hall of Fame, and the World Academy of Sciences. Website: https://www.drtheoharides.com LinkedIn: linkedin.com/in/theoharis-theoharides-ms-phd-md-faaaai-67123735 Instagram: https://www.instagram.com/dr.theoharides/ Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet. Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com Instagram: https://www.instagram.com/hayliepomroy Facebook: https://www.facebook.com/hayliepomroy YouTube: https://www.youtube.com/@hayliepomroy/videos LinkedIn: https://www.linkedin.com/in/hayliepomroy/ X: https://x.com/hayliepomroy Enjoy our show? Please leave us a 5-star review on the following platforms so we can bring hope and help to others. Apple Podcasts: https://podcasts.apple.com/us/podcast/hope-and-help-for-fatigue-chronic-illness/id1724900423 Spotify: https://open.spotify.com/show/154isuc02GnkPEPlWfdXMT Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d Enjoy our show? Please leave us a 5-star review on the following platforms so we can bring hope and help to others. Apple Podcasts: https://podcasts.apple.com/us/podcast/hope-and-help-for-fatigue-chronic-illness/id1724900423 Spotify: https://open.spotify.com/show/154isuc02GnkPEPlWfdXMT Sign up today for our newsletter. https://nova.us4.list-manage.com/subscribe?u=419072c88a85f355f15ab1257&id=5e03a4de7d This podcast is brought to you by the Institute for Neuro-Immune Medicine. Learn more about us here. Website: https://www.nova.edu/nim/ Facebook: https://www.facebook.com/InstituteForNeuroImmuneMedicine Instagram: https://www.instagram.com/NSU_INIM/ Twitter: https://www.twitter.com/NSU_INIM
- Geopolitical Developments and Book Updates (0:10) - Introduction to Terawatt Tantrums (2:26) - Challenges in Power Infrastructure (5:46) - Nuclear Power and Dependence on Russia (10:33) - Challenges in Building Nuclear Power Plants (15:02) - Alternative Energy Sources and Challenges (20:53) - China's Lead in AI and Power Infrastructure (23:45) - The Future of AI and Power in the U.S. (52:42) - Brighteon Book Engine Updates (52:59) - Censorship and the Role of AI (1:20:32) - Censorship and the Truth About Money (1:22:53) - Censorship in the Ukraine-Russia Conflict (1:30:35) - Censorship in Virology and Immunology (1:33:33) - Censorship in Evolution and Climate Change (1:41:12) - Censorship and Depopulation Agendas (1:46:55) - Introduction to "Terawatt Tantrums" (1:48:52) - China's Energy Advantage (1:52:41) - The Importance of Energy Independence (1:53:00) - Call to Action for Energy Independence (1:54:18) - Promotion of Health Ranger Products (1:58:01) For more updates, visit: http://www.brighteon.com/channel/hrreport NaturalNews videos would not be possible without you, as always we remain passionately dedicated to our mission of educating people all over the world on the subject of natural healing remedies and personal liberty (food freedom, medical freedom, the freedom of speech, etc.). Together, we're helping create a better world, with more honest food labeling, reduced chemical contamination, the avoidance of toxic heavy metals and vastly increased scientific transparency. ▶️ Every dollar you spend at the Health Ranger Store goes toward helping us achieve important science and content goals for humanity: https://www.healthrangerstore.com/ ▶️ Sign Up For Our Newsletter: https://www.naturalnews.com/Readerregistration.html ▶️ Brighteon: https://www.brighteon.com/channels/hrreport ▶️ Join Our Social Network: https://brighteon.social/@HealthRanger ▶️ Check In Stock Products at: https://PrepWithMike.com