Podcasts about Biochemistry

ReferencesNat Immunol. 2018 Jul9;19(8):871–884. J Immunol Res. 2025 Jul17;2025:9328523Biochem Biophys Res Commun. 2024 Mar 12:700:149598.Int J Mol Sci. 2019 Oct; 20(19): 4962.Tempchin, G 1972 Peaceful Easy Feeling. Eagleshttps://music.youtube.com/watch?v=n-0lRkuNyj0&si=7cBHTtUT8_c2yC7xCorelli, A. 1700. Violin Sonata in D Minor. OP 5. No.7https://music.youtube.com/watch?v=uRv44TQTacA&si=fp8rT4JDtFRsD4ij

ReferencesGuerra, DJ. 2026 Unpublished Lecture.Cell. 2021 Apr 1; 184(7):Cell. 2024. Volume 187, Issue 3 p733-749.e16February 01.Nat Immunol. 2018 Jul9;19(8):871–884. Vinson and Chatmon. 1930 Sitting on top of the World. Cream. Wheels of Fire lp.https://open.spotify.com/track/0aY5bJ4jRHiOd8eCMWmcy8?si=a969586b68694b0eLamb, R. 1972. Dialogues I&II Chicagohttps://open.spotify.com/track/02F55MPyLuAUnSSvDg4lP4?si=f9a8d6e6ff0c41e4Pankow,J.1969. Liberation. Chicago Transit Authorityhttps://open.spotify.com/track/385g7dy2YZ1uNV9AJhOpUv?si=b316eef0684e4682

If you want to get leaner and live longer check out https://milliondollarbodylabs.com Are you tired of feeling like your energy and focus are slipping away because your "control panel" is out of whack? I explore the control panel of health: hormones. For this episode I pulled together expert insights from episodes I recorded before to build a roadmap for health. I talk with Ali Gilbert, who explains why cholesterol is the base for testosterone and estrogen production. She breaks down factors for health: brain, biochemistry, and blood flow. Dr. Alan Christianson describes how compounds in plants heal receptors and how stress causes famine mode. Patricia Zamora speaks on the testosterone drop and why sleep is the requirement for recovery. Jared St. Clair details how toxins block receptors like houseguests. We talk about clinics and how to navigate treatment. This roadmap helps you manage energy and fat loss through biology.   Key Takeaways Cholesterol is Essential: Approximately 50% of your hormones are manufactured from cholesterol; driving levels too low can starve hormone production. The Three B's of Sexual Health: Performance issues often stem from the Brain (stress), Biochemistry (hormones), or Blood Flow (arterial health). Plant Compounds Heal Receptors: Phytonutrients in foods like walnuts and soy can "plug up" bad receptors and help "good" receptors function better. Stress Triggers "Famine Mode": High stress levels signal the body to store fat and burn less fuel as a survival mechanism. The "Logjam" Theory: Environmental toxins act as "unwanted houseguests" in your receptors, blocking natural hormones from delivering their messages. Sleep is the Priority: Testosterone is primarily made overnight; chronic sleep deprivation is a leading cause of the current low-testosterone epidemic.   Resources Mentioned Experts: Ali Gilbert, Dr. Alan Christianson, Patricia Zamora, Jared St. Clair, Dr. Eric Serrano, Dr. Michael Twyman.   Nate Palmer: The founder of The Million Dollar Body and author of "The Million Dollar Body Method", Nate has been coaching for over 15 years and has worked personally with over 1,000 clients. Website: https://milliondollarbodylabs.com Book: The Million Dollar Body Method Lean Energy Stack: https://milliondollarbodylabs.com/pages/lean Instagram: @_milliondollarbody  

This episode features the 21st Haines Lecturer in Biochemistry, Jason Kwon '11, discussing the impact of artificial intelligence on his scientific work, the evolving optimization problem of work-life balance, and memories of Wabash weekends at the TKE house (Episode 401).

ReferencesCell. 2021 Apr 1; 184(7):1790–1803.e17Methods Mol Biol. 2022; 2497:129–140. Guerra, DJ.2026. Unpublished LecturesClapton/Bruce/Brown. 1967 Sunshine of your Love Live Cream Vol IIhttps://music.youtube.com/watch?v=tVCeZvusHCU&si=LzcFIKnxe0GP461mHenley/Browne, 1972, Take it Easy Eagleshttps://open.spotify.com/track/4yugZvBYaoREkJKtbG08Qr?si=915e639119db4c91Miller, R. 1962 King of the Roadhttps://open.spotify.com/track/3XG7bMVcMWLIn2k9jLAaAt?si=68578db0407f452f

ReferencesCurr Opin Allergy Clin Immunol 2025, 25:444–454Guerra. DJ.2026. Unpublished Lectures.BiolOpen. 2019 Oct 15; 8(10): bio040311Lennon/McCartney. 1966. Rain. Beatleshttps://open.spotify.com/track/48TNLcToLs8DWkdj5vYdiW?si=375c43203c1c4ccdClapton/Bramlett, 1970. Let it Rainhttps://open.spotify.com/track/7DiaNCPgH5dJ1cJ925jTAA?si=b8bfac43cdef493cPage/Plant. 1973. The Rain Songhttps://open.spotify.com/track/3JLrri1xSCui3bzITDJbkk?si=6c47b7b4a0974806 Townsend, P. 1973. Love, Reign O'er Me. The Whohttps://open.spotify.com/track/4Mqs0h95KAeNiGp7u4udlt?si=56521c6a1b71425aLightfoot, G. 1975. Rainy Day Peoplehttps://open.spotify.com/track/1TZteKaf5z3P3i87jyB8jc?si=def4f81ab3ef4100

ReferencesNature Immunology 2018. volume 19, pages871–884 Guerra, DJ. 2026 Unpublished Lectures ChemBioChem,2018. .: 19, Issue: 15, Pages: 1657-1663, Morrison/Manzarek/Krieger/Densmore. 1971. Riders on the Storm. Doors.https://open.spotify.com/track/14XWXWv5FoCbFzLksawpEe?si=ee8db94467dd4d0a

Why Don't They Win  There are moments, usually late, usually quiet, when honest thinking can be had. When you zoom out and see the ecosystem around children not as a collection of caring institutions, but as a set of incentive machines. And incentive machines, unlike grandmothers, do exactly what they're built to do. MAKE MONEY Tonight I sat with some difficult thoughts about the state of primary services for children in the United States. The deeper I look, the clearer it becomes that money, not well-being, drives most decisions shaping a child's life. And the imbalance is not trending in a positive direction. Children Continue To Lose From My Viewpoint Approximately two-thirds of a child's daily nourishment comes from school food programs, which too often rely on ultra-processed, calorie-dense, nutrient-poor products. Outside of school, the dominant food environment is similarly saturated with highly engineered foods that optimize profit, shelf life, and palatability rather than health. Kids are micronutrient starved, but calorically overfed. Biological systems begin to fray early. Biochemistry no longer meets cellular needs. Children develop disease and we are asked to medicate or worse rationalize away that this is NORMAL..... Enjoy Dr. M

ReferencesMBOC 2011. Volume 22, Issue 18 3456–3464Guerra, DJ. 2026. Unpublished LecturesDiscoveries (Craiova). 2014 Sep 23;2(3):e29J Cell Mol Med. 2015 May 28;19(7):1427–1440J Cell Mol Med. 2015 May 28;19(7):1427–1440Signal Transduction and Targeted Therapy2025. volume 10, Article number: 254Dylan, B. 1964 Mr. Tambourine Manhttps://open.spotify.com/track/3RkQ3UwOyPqpIiIvGVewuU?si=7127b25041cf4972 Zevon, W. 2003. Keep Me in Your Heart for a Whilehttps://open.spotify.com/track/1fRlDQzrpvWd4BlIzifUkJ?si=0a8e5251592e49eaMozart, WA. 1773. Symphony 25 in G Minor K.183https://music.youtube.com/playlist?list=OLAK5uy_nYdGMRH0VYkIzQZQhIlX3utzG2dlDWurk&si=g3zc1O-3naltl3I7

ReferencesGuerra, DJ 2026. Unpublished LecturesBiol Open. 2019 Oct 15; 8(10): bio040311.Small GTPases. 2012 Jul 1;3(3):139–153.Cell Mol Biol Lett. 2024 Aug 10;29:108Front Immunol. 2019 May 31;10:1225Brain Commun. 2021 Mar 5;3(2):fcab020Balin M. 1967. Coming Back to Me Jefferson Airplanehttps://open.spotify.com/track/0TBntp6t4oS6UXjxikO5n7?si=ccff17969d2c4680Kokkonen, J. 1972. Water Song Hot Tuna https://open.spotify.com/track/5Qe0nAjBVDecK7SfZE9YUm?si=4c8689cc0a2e4a1ePaige, J 1974 Bron yr Aur Zeppelinhttps://open.spotify.com/track/5rgWj8h7lzbSmwpp0wFkXD?si=d08d8d2b18bc40dc

ReferenceseLife. 2022 Nov 25;11:e83073Lipids Health Dis. 2025 Jul1;24:225Cell Reports 2021 Volume 35, Issue 5109076May 04.Guerra, DJ. 2026 Unpublished LecturesMcGuinn/Parsons/White et al. 1968 Sweetheart of the Rodeo. The Byrdshttps://music.youtube.com/playlist?list=OLAK5uy_kejb97oJ9VJCssjIxpz2YeHK9htTy-wz0&si=kkIqFi6NfkhHCpl9

ReferencesGuerra. DJ 2026. Unpublished LecturesLipids Health Dis. 2025 Jul1;24:225Jagger/Richards. 1969 Paint it Blackhttps://open.spotify.com/track/63T7DJ1AFDD6Bn8VzG6JE8?si=7cb90ffb26b54512Beethoven LV. 1804 Symphony 3 in E Flat Major. Eroicahttps://music.youtube.com/watch?v=fhHcty9OM-0&si=ZWJt3uJUkjXY9ujt

Organic chemistry has a reputation for being one of the most challenging college courses—but what if it could also be interactive, accessible, and even fun? On this exciting episode of Let's Talk Chemistry edited by Jasmine Winter, hosts Jasmine Winter and Elizabeth Li share the story of Dr. Neil Garg, Professor of Chemistry and Biochemistry at the University of California, Los Angeles. Dr. Garg discusses his journey from discovering his passion for organic chemistry as an undergraduate to earning his PhD at Caltech and building a career that bridges both research and education. Dr. Garg's career is built on challenging the status quo, from breaking a 100 year-old rule in chemistry known as Bredt's rule, to developing innovative tools to help students better visualize and understand molecular structures. Dr. Garg emphasizes teamwork, intellectual curiosity, and making science approachable for learners of all ages. We hope you enjoy!

Mehlman Qbanks: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://qbanks.mehlmanmedical.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/mehlman_medical/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Telegram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://mehlmanmedical.com/subscribe/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

ReferencesiScience 2024. 27, 109267, March 15, Front. Immunol., 2018,03 December Sec. T Cell Biologyv9Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7661–7666Townsend, P 1973. Im One The Who Quadrophenia. https://music.youtube.com/watch?v=qvPVw0l5XpY&si=jHjslRqdHZH21KGHMozart, WA 1786. Piano Concerto in A Major. K 488.https://music.youtube.com/watch?v=V4S6UYv8-W4&si=AmbTM2OPzO10wJjx

ReferencesGuerra, DG. 2026. Unpublished LecturesLipids Health Dis. 2025 Jul 1;24:225Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7661–7666Leadon/Frey/Henley/Meiser/Blue/Souther/Norman. 1973 Desperado Eagleshttps://music.youtube.com/playlist?list=OLAK5uy_k3UBMdBe0k-PWX6y1VCLJZVJogoUaKEco&si=KAdQVnU-qVFn_r52

How much stress do you take on in your everyday life, and what effect does this stress have on your body's ageing? For more on this, Pat is joined by Luke O'Neill, Professor of Biochemistry at the School of Immunology, Trinity College.

ReferencesJ Biol Chem. 2011 Apr 8; 286(14): 11937–11950.Cardiovasc Diabetol.2020; 19: 33.J Cell Physiol. 2021 Apr;236(4):2333-2351Cytometry 2006. Part A 69 Issue 3Mar. Pages105-208Lennon/McCartney. 1964 Hard Day's Night. lphttps://music.youtube.com/playlist?list=OLAK5uy_kNANFuHzr_3bZH3S5aXxOT4X1ouKnjY4k&si=02aKQ86d5RTfyyY7CSNY, 1970. Deja Vu lp.https://music.youtube.com/playlist?list=OLAK5uy_neUnMuHswIr4wB5qPiV5iozF-550Cz3k8&si=neIOWnSei3lU7e07

ReferencesAm J Physiol Cell Physiol. 2020 Dec 9;320(3):C415–C427Cell Physiol Biochem. 2015 Feb 11;35(4):1253–1275. Molecular Cancer 2017. 16(1)DOI: 10.1186/s12943-017-0699-3Guerra, DJ 2026. Unpublished LecturesMozart, WA. 1787. Don Giovanni Overture K.527https://open.spotify.com/track/7JINUFIVIptR7hlQYayU3h?si=5d92671383214c71

Conserved neuropeptide Y GPCRs orchestrate both feeding and mating behaviors in mosquitoes, with direct translational parallels to human gut-brain signaling.Quick SummaryLearn how receptor internalization and neuropeptide GPCR signaling underlie the regulation of mosquito host-seeking and reproduction. Dr. Laura Duvall details the use of CRISPR-based assay development and fluorescence-driven phenotyping to connect molecular manipulation to whole-animal behavior. Her approach provides actionable insights for gpcr drug discovery and tools to dissect homologous pathways across model systems, with implications for pharmacology research targeting vector-borne disease transmission.Key TakeawaysNeuropeptide Y GPCRs modulate both host attraction and mating in Aedes aegypti.CRISPR and fluorescence assays enable precise behavioral phenotyping in vivo.GPCR-targeted compounds designed for humans can modulate mosquito receptors.NPY receptor expression in mosquito gut mirrors mammalian gut-brain signaling axes.Automated behavioral assays combined with machine learning sharpen data resolution and reduce human bias.Dr. GPCR Links & ResourcesExplore essential resources:Dr. GPCR EcosystemMembership & PricingWeekly NewsAdvance your research—discover the power of Dr. GPCR Premium.About the GuestDr. Laura Duvall earned her B.A. in Biochemistry and Biological Basis of Behavior from the University of Pennsylvania, followed by a PhD at Washington University in St. Louis, where she explored neuropeptide regulation of circadian behavior in Drosophila. Transitioning from fruit flies to mosquitoes, she pursued postdoctoral research at Rockefeller University with Leslie Vosshall, focusing on the molecular regulation of feeding and mating behaviors in Aedes aegypti. In 2019, she established her independent laboratory at Columbia University's Department of Biological Sciences and the Zuckerman Institute. Dr. Duvall's work is recognized by awards including the Beckman Young Investigator Award, Klingenstein-Simons Fellowship in Neuroscience, and the Pew Scholars Program, reflecting her drive to unravel the complex signaling mechanisms that govern mosquito and broader animal behavior.Guest on The WebLinkedIn: https://www.linkedin.com/in/laura-duvall-28a03485/Google Scholar: https://scholar.google.com/citations?user=Vk3KGSoAAAAJ&hl=enLab: https://www.duvalllab.com/

referencesCell Death & Disease 2026. 17, Article number: 71 Am J Physiol Cell Physiol. 2020 Dec 9;320(3):C415–C427Guerra, DJ.2026. Unpublished LecturesJagger/Richards. 1964. As Tears Go By. Marrianne Faithful https://open.spotify.com/track/2EYXCRp63iQdmeKHXN8Rrg?si=70ceced5d9304eb8Mozart , WA 1779. Sinfonia Concertante in E flat Major K.364https://music.youtube.com/watch?v=_0hTDZ0whpU&si=NNbjswoPokVPveuu

In nature, enzymes are the catalysts that make much of biology work. They jumpstart chemical reactions that either wouldn't happen, or would happen super slowly. They break down food, build other molecules, extract energy, and more. What if we could harness evolution to engineer designer enzymes that do other specific jobs that benefit us?  Putting that idea into practice changed the game for chemistry, and earned Frances Arnold the Nobel Prize prize in 2018. She called it “directed evolution.” Today, thousands of labs use her methods to coax enzymes into doing things no one ever thought of. She joins Host Flora Lichtman to talk about where she sees this approach going in the future, and the personal evolution that brought her into science. Guest: Dr. Frances Arnold is the Linus Pauling Professor of Chemical Engineering, Bioengineering and Biochemistry at the California Institute of Technology in Pasadena, California.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

ReferencesGuerra, DJ. 2026. Unpublished LecturesScience Translational Medicine 2019: 17 Jul. Vol. 11, Issue 501, eaav7816Lennon/McCartney. 1969. Let it Be Beatleshttps://open.spotify.com/track/7iN1s7xHE4ifF5povM6A48?si=77799fa1a6ca494e

ReferencesGuerra, DJ. 2026 Unpublished LecturesCell.2022 Jun 16;185(14):2542–2558.e18. https://omim.org/entry/607358Experimental & Molecular Medicine2025 57:1881–1892Hunter/Garcia, 1968. Dark Star Grateful Dead Live/Dead LP https://open.spotify.com/track/07CwWCJetytT1cSnQOgRMU?si=de8e173488834efb

Dr. Aimie Apigian returns to explore how unresolved trauma and chronic survival stress can evolve into fatigue, autoimmune symptoms, digestive issues, and brain fog. This conversation dives into why high-functioning, driven individuals often feel depleted despite appearing “fine,” and how nervous system dysregulation keeps the body stuck in a state of danger.Learn how restoring safety, regulating the nervous system, and repairing biology can reverse chronic symptoms and build true resilience from the inside out.Key Takeaways:Autoimmune symptoms may reflect a nervous system stuck in chronic danger mode.High-achieving, perfectionist personalities are more prone to trauma-driven depletion.Emotional overwhelm can trigger immune activation and brain inflammation.Digestive dysfunction and fatigue often stem from vagus nerve shutdown and metabolic stress.Healing begins with restoring safety and regulating the nervous system before processing trauma.Dr. Aimie Apigian Bio:Dr. Aimie Apigian, MD, MS, MPH, is a double board-certified physician in Preventive and Addiction Medicine with advanced degrees in Biochemistry and Public Health. She is the founder of The Mind-Body-Biology Institute and creator of The Biology of Trauma®, a pioneering framework that integrates medicine, neuroscience, and somatic therapies to address how trauma is stored in the body—and how to heal it. Inspired by her personal journey as a foster and adoptive mother, Dr. Aimie blends rigorous science with deep compassion to help individuals and practitioners achieve lasting transformation. Her book, The Biology of Trauma, reveals the cellular and emotional roots of fear, pain, and overwhelm, and offers a practical path to true mind-body-biology healing.The Biology of Trauma: Your Issues are Stuck in Your Tissues with Dr. Aimie Apigian

Send a textRole of bile acids in cholesterol regulation, digestion & metabolic diseases like diabetes.TOPICS DISCUSSED:Bile acids basics: They enable cholesterol excretion, with about half of bodily cholesterol eliminated this way, and also aid digestion by emulsifying fats to increase enzyme access.Bile production & pathway: Synthesized in liver hepatocytes, bile flows via ducts to the gallbladder for storage or directly to the small intestine; post-meal, cholecystokinin triggers gallbladder contraction for fat emulsification.Regulation of bile acids: Self-regulated to prevent cytotoxicity, as excess can damage cell membranes; insulin and bile acids themselves influence synthesis and transport, with defects in insulin-resistant states.Bile acids in metabolic diseases: Increased synthesis, especially 12-hydroxylated types, occurs in type 2 diabetes and insulin resistance, potentially as an adaptation for better nutrient absorption during perceived scarcity.Gallbladder removal & gallstones: Common due to cholesterol supersaturation forming stones; removal eliminates concentration but preserves bile flow, reducing tolerance for high-fat meals.Bariatric surgery impacts: Procedures like gastric bypass increase circulating bile acids without major synthesis changes, while more extreme ones boost synthesis due to impaired intestinal sensing.Cholesterol homeostasis: Cells tightly regulate membrane cholesterol for fluidity and signaling; most bodily cholesterol is synthesized internally, with LDL receptors key to blood levels.Ongoing research: Haeusler's lab explores manganese's role in metabolism, bile acids in liver inflammation, and insulin's effects on lipoproteins.ABOUT THE GUEST: Rebecca Haeusler, PhD is an associate professor at Columbia University in the departments of medicine and pathology and cell biology, affiliated with the Naomi Berrie Diabetes Center and the Digestive and Liver Diseases Research Center.RELATED EPISODE:M&M 269 | Soybean Oil: Obesity, Fatty Liver Disease, Gut Health, IBS & Colitis | Frances SladekSupport the showHealth Products by M&M Partners: SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

ReferencesImmun Ageing. 2020; 17: 2.Trends in Immunology. 2017. REVIEW| VOLUME 38,ISSUE 4, P287-297, APRIL 01, Int J Mol Sci. 2025 Apr 27;26(9):4147Experimental & Molecular Medicine 2019. volume 51, Article number: 80 Beethoven, LV 1811. Piano Concert V in E Flat Major OP 73.https://music.youtube.com/watch?v=q-hn8WH_-3U&si=TNpna_2DZLIoX2nM

ReferencesSCIENTIFIC REPORTS 2016 | 6:34594 | DOI:10.1038/srep34594 Seminars in Immunology 2025. V. 78,Jun, 101954Front Immunol. 2025 Jan 8:15:1515715Telemann, GP. 1735. Sinfonia Spirituosa TWV 40&50https://open.spotify.com/album/2nJX3LIjdAbNIGR3qbQaBI?si=VF-7aHcBS_qOkEsl34LdKQ

In this episode of Money Tales, our guest is Stephanie Ellis-Smith. Marriage caused Stephanie to face two hard truths at once. The medical career she had poured herself into did not fit the life she wanted to build with her husband. And perhaps even more unsettling, a career in medicine was not clicking the way she had always assumed it would. When she stepped away, Stephanie felt like she was walking out on an identity her family had invested everything in. Her dad even told her, quite bluntly, that she had no employable skills. Then, in the middle of that uncertainty, Stephanie said yes to a small volunteer opportunity. That single yes ended up rerouting her life into a decades long career in philanthropy, including founding three nonprofits and Phila Engaged Giving. Stephanie is the CEO and founder of Phīla Engaged Giving, a philanthropic advisory firm established in 2017 that works with donors who are ready to activate their assets for social change. As an advisor and social impact specialist, she works toward a world where philanthropy is a nurturing and equity-centered practice that connects wealth to the people and communities who need it most. Stephanie is a Chartered Advisor in Philanthropy (CAP®) with extensive experience in advising high-impact individuals and companies. She believes strongly in being a compassionate and generous member of society and brings nearly 30 years of professional and personal life experience in governance, family wealth and nonprofit leadership to the social sector. In the wake of the racial uprisings of 2020, she co-founded Giving Gap, an online database to help donors find and support Black-founded and led organizations in their communities. Having served in a variety of professional capacities—non-profit CEO, social enterprise COO, foundation and non-profit trustee and corporate board member—Stephanie's extensive background and deep knowledge makes her uniquely well-positioned to be a trusted advisor to the world's most generous families and institutions. Stephanie's expertise in navigating wealth, impactful generosity and civic engagement is frequently sought by leading philanthropic institutions and mainstream publications and she has frequently appeared as a keynote speaker at major social sector convenings. Several Seattle mayors and former Washington Governor Gary Locke have appointed Stephanie to serve on a variety of boards and public commissions. She is currently a member of the Seattle Art Museum's Museum Development Authority Board and the board of the National Center for Family Philanthropy. She was appointed a Dean of Philanthropy in 2022 by The Purposeful Planning Institute. Stephanie has BA degrees from UCLA in both English Literature and Biochemistry. Given her keen interest in science, Stephanie's post-graduate years were spent in university labs working on stem cell and AIDS-related research. She has two adult children and lives in Seattle with her husband, the historian Douglas Smith. Finding Purpose Through Philanthropy Stephanie's journey shows that philanthropy is far more than writing checks or serving on boards. It is a deeply human practice that shapes relationships, careers and how we understand money, power and purpose. From her own career pivot to the way she helps families navigate charitable giving, her story illustrates how generosity can change the giver as much as the causes they support. By speaking openly about her own money story, identity and career reinvention, she reminds listeners that meaningful giving begins with honest conversations and a willingness to learn. If you are thinking about how to align your wealth with your values, an Aspiriant advisor can help you clarify your purpose, structure your giving and build a thoughtful philanthropic plan that fits your family. Follow Money Tales on Spotify, Apple Podcasts or YouTube Music for more real stories that help us make smarter, more intentional decisions with our money.

ReferencesAntimicrob Agents Chemother. 2017 Dec 21;62(1):e01614-17Br J Cancer. 2002 Mar 18;86(6):963–970Science Translational Medicine 2019: vol. 11, Issue 501, 17 Jul Int J Mol Sci. 2025 Apr 27;26(9):4147 Fogerty, J 1969. Fortunate Son. CCRhttps://open.spotify.com/track/4BP3uh0hFLFRb5cjsgLqDh?si=5b6bd7dea0774f9dHunter/Garcia. 1973 It Must Have Been the Roses. Grateful Dead [Reckoning] lphttps://music.youtube.com/watch?v=tvXQ7r-n-Go&si=J6mTP9rquTHkNo-D

In this enlightening episode of the Transform Your Mind personal development podcast, mindset expert Myrna Young sits down with pioneer and transformation coach Harry Massey to explore the cutting-edge world of bioenergetics and holistic health. This conversation delves into how Harry transformed his own health crisis into a thriving career dedicated to uncovering the root causes of chronic illness beyond conventional medicine. With a fascinating blend of personal storytelling and scientific insight, Harry discusses why bioenergetics might hold the key to understanding the human body's true energy field and the limits of traditional health systems. Discover how this breakthrough approach can support inner transformation, wellness, and healing on a deeper level.Harry's journey from a catastrophic accident to becoming a leader in bioenergetics. How the limitations of Western and even holistic medicine led him to study energy and physics. Packed with intriguing revelations about how emotional blockages and energy drains might be the true culprits behind our illnesses. Accompanied by insights on groundbreaking technologies like the MI Health device and GEM wearables, Harry shares practical wisdom on healing at the energetic level, offering listeners a transformative perspective on wellness, function, and personal empowerment.Timestamp Summary0:02 Harry Massey's Journey From Tragedy to Bioenergetics Pioneer8:19 Exploring Bioenergy and Its Connection to Chakra Systems13:01 Stress, Energy, and the Limitations of Medicine16:01 The Limitations of Biochemistry and the Power of Bioenergetics24:01 Managing Emotional Energy Through Gratitude and Mindfulness Techniques27:27 Harnessing Gratitude and Intention for Personal and Professional Success35:20 Harnessing Emotional Energy for Healing and Manifestation45:43 Harnessing Energy and Gratitude for Healing and TransformationResources:Harry Massey's Personal Website: HarryMassey.comEnergy for Life Website: e4l.comGEM Wearable Technology:  e4l.com/gemSponsored Ad Airdoctor If you want to upgrade the air in your home,  Head to AirDoctorPro.com and use promo code transform to get UP TO $300 off today!  Breathe better. Live better.”See this video on The Transform Your Mind YouTube Channel https://www.youtube.com/@MyhelpsUs/videosTo see a transcripts of this audio as well as links to all the advertisers on the show page https://myhelps.us/Follow Transform Your Mind on Instagram https://www.instagram.com/myrnamyoung/Follow Transform Your mind on Facebookhttps://www.facebook.com/profile.php?id=100063738390977Please leave a rating and review on iTunes https://podcasts.apple.com/us/podcast/transform-your-mind/id1144973094 https://podcast.feedspot.com/personal_development_podcasts/ For sponsored Brand interviews and sponsorship inquires please visit Partner With The Transform Your Mind Podcast | Myrna Young Life Coach

ReferencesStem Cell Res Ther. 2018 Dec 7;9:342Developmental Cell. 2024. V.59, Issue 2:211-227.e5January 22, Cell Commun Signal. 2023 Sep 19;21:244.Cell Discov 2024. 10, 71.Baker/Taylor. 1968 Passing the Time Cream WoFhttps://open.spotify.com/track/7wxd5oR50LKSTtqqJQxYSX?si=4e7a91cc8f6e463cPisendel, JG. 1717. Sonata in G Minorhttps://music.youtube.com/watch?v=beAdy0DoWEk&si=CCs2BQwfundJ65-u

Luke O'Neill, Professor of Biochemistry and Immunology at Trinity College, talks to Brendan about ‘Sniper's Alley' - the period of time around your fifties when you start becoming more susceptible to negative health events. He explains how to bulletproof yourself before you enter Sniper's Alley and has general tips for better health for us all.

ReferencesJ Biol Chem 2017 292: 20481.Cell Metabolism. 2018. 27.,3 p602-615.e4March 06Proc Natl Acad Sci U S A. 2010 May 8;107(21):9626–9631Proc Natl Acad Sci U S A. 2011 May 18;108(23):9466–9471Guerra,DJ. 2026. Unpublished LecturesHoward, B. 1954.Fly Me to the Moon. Sinatrahttps://open.spotify.com/track/7FXj7Qg3YorUxdrzvrcY25?si=3104a016654d4bb9Sparks, A. "Pinetop" 1935. Every Day I Have the Blues. Count Basis and Joe Williamshttps://open.spotify.com/track/1ZVV4uUYilEdZRySfKjvpx?si=62de0af91e7648f0Kaukonen, J. 1971. Third Week in Chelsea. JAhttps://open.spotify.com/track/5t5bV1HLuULF0bX1F6MfCv?si=d65795563a324df7

Eva is an Associate Professor at the University of New England, where her research focuses on proteins and utilizes biochemistry, biomaterials, and biophysics. She is also deeply interested in antidisciplinary, collaborative research. Eva was a 5 Minute Genius™ speakers at the 2024 Maine Science Festival; you can see her talk on our YouTube channel. This conversation was recorded in December 2025. ~~~~~The Maine Science Podcast is a production of the Maine Discovery Museum. It is recorded at Discovery Studios, at the Maine Discovery Museum, in Bangor, ME. The Maine Science Podcast is hosted and executive produced by Kate Dickerson; edited and produced by Scott Loiselle. The Discover Maine theme was composed and performed by Nick Parker. To support our work: https://www.mainediscoverymuseum.org/donate. Find us online:Maine Discovery MuseumMaine Discovery Museum on social media: Facebook Instagram LinkedIn Bluesky YouTubeMaine Science Podcast on social media: Facebook Instagram YouTubeMaine Science Festival on social media: Facebook Instagram LinkedIn YouTube© 2026 Maine Discovery Museum

ReferencesBMC Biology2011 9:85Biomedicines 2023, 11(7), 1804Cancer Res (2011) 71 (2): 293–297Biophysics J. 2018. Volume 114, Issue 1, 9 January: 126-136Proc Natl Acad Sci U S A. 2024 Jan 4;121(2):e2311700120. Guerra, DJ. 2026. Unpublished Lectures.Aurelius Augustinus Hipponensis. St. 387 De libero arbitrio voluntatis.Hunter/Garcia. 1974. Scarlet Begoniashttps://open.spotify.com/track/3euDGpS2R0NC2Xssqxohva?si=1985f2fff9f146d6Simon, P. 1969. The Boxer, S&G.BoTWhttps://open.spotify.com/track/76TZCvJ8GitQ2FA1q5dKu0?si=5e15f1cdf43a4083

References Oncogene 2019. February 38(8)J Cell Mol Med. 2015 Jul; 19(7):1427–1440. J Cell Mol Med 2014 Oct;18(10):1927-37. Langmuir, 2018, 34 (1), pp 530–539Cancer Res (2011) 71 (2): 293–297BMC Biology2011. 9:85Paganini, N 1826 and 1830 Violin concerti 3 in E Major MS 50 & 4. in D minor, MS 60https://music.youtube.com/playlist?list=OLAK5uy_nzsMMijsYXkkGukLlhJjs-RngqpJekOdU&si=6Aide_5wbvs3CzkE

ReferencesCell 2011 Volume 146, Issue 3, 5 August Pages 408-420Biochim Biophys Acta. 2011 Jun;1811(6):377-85Cells. 2024 May 3;13(9):781. Page/Plant 1971. When the Levee Breaks LZ IVhttps://open.spotify.com/track/7psfcbjfnXwYIezHstNa1a?si=3b2a11090a494510Van Heusen, J /Cahn,S. 1964. My Kind of Town. Sinatrahttps://open.spotify.com/track/6jnmiFauoWEtg5yXLJYzzF?si=e84563bcb19d45fd

ReferencesGuerra, DJ 2026 In PreparationThomas, R .1969. Eternity Road FoCC. Moody Blueshttps://open.spotify.com/track/13z2K32dMaQLDohef5Ndne?si=2493932acf2945f2

ReferencesJ Biol Chem. 2012 Nov 23;287(48):40131-9PLoS Biol 2014. 12(10): e1001969.doi:10.1371/journal. BioNature, 2019. vol. 575, no. 7783, Nov, pp. 361+.Trad. 1972. I Know You Rider Grateful Deadhttps://open.spotify.com/track/2M7u9Anw0WbTLsCIHxRoV3?si=7564411354c8414d

ReferencesGuerra, DJ. 2026. Unpublished lecturesGuerra. DJ. 2022. J of Disease and Global Health Volume 15 [Issue 3]:22-47.Essays Biochem. 2018 Jul 20;62(3):341–360J Am Chem Soc. 2025 Jul 8;147(28):24258–24274.Bach, JS 1726. Partita for Clavier in D Major BMV828https://music.youtube.com/watch?v=M3k0gSDSYPM&si=m3ANN3qws1OEI67hTelemann , GP. 1720 (?) Sonata in F Minor for trombonehttps://music.youtube.com/watch?v=cfal1EV64gs&si=ET_6TxL2xQ_vpoL6

This episode features a conversation with Isuru Vidanage, the Wine Buyer at Elemental Spirts Co. in Atlanta, GA. Born in Houston, TX to Sri Lankan immigrants, Isuru went to high school in Macon, GA and later moved to Atlanta for college. He earned a degree in Biology with a distinction in Biochemistry and Evolutionary Biology and Behavior followed by working at the Centers for Disease Control and Prevention in the Organic and Analytical Toxicology Branch. We talk about his work and how his team's focus was on understanding how populations within the U.S. and abroad were being exposed to pesticides. He talks about how he ultimately left the CDC to pursue other passions, and he ultimately found his way to the world of retail wine. You'll hear his insights about the Atlanta wine scene and how his love for community, culture, and cooking are helping to elevate his own wine education – I even challenge him to dream up who he would invite to a bucket list dinner party. You can follow @elementalspirits.co on Instagram to learn more about his work and see what wines he is showcasing at the shop.Recorded February 10, 2026 -----------------*** Check out our ⁠⁠MERCH SHOP⁠⁠ to directly support the show, and visit www.acorkintheroad.com for all upcoming events and press releases

ReferencesGuerra, DJ 2026.unpublished lecturesAdv Sci (Weinh). 2024 Oct18;11(46):2404033.Kristofferson. C. 1969.Me and Bobby McGee. Grateful Deadhttps://music.youtube.com/watch?v=RqvX083cFc8&si=x7-qhXWgKFxhRFK5Dvorak, A 1893 . New World Symphony #9. in E Op. 95, B. 178https://music.youtube.com/watch?v=jOofzffyDSA&si=oPNIZAOeYhsjoiWV

ReferencesDiscoveries (Craiova). 2017 Jul-Sep; 5(3): e77. Adv Sci (Weinh). 2024 Oct 18;11(46): 2404033.Guerra, DJ.2026. Unpublished Lectures Biber, HI. 1676. Violin Sonata 84 in E. c.108https://music.youtube.com/watch?v=RujpXPN4ooU&si=kth4IP6bHzHjG4HB

ReferencesCell Death & Disease 2022. volume 13, Article number: 444 Cancer Cell. 2010 Feb 18;17(3):225–234Biochem Biophys Rep. 2020 May 20;22:100769eLife. 2015 Jul 31;4:e07420. Biochemistry2013. June. 52(26)Joel, B. 1978 Honesty. https://open.spotify.com/track/34E0Higz6fFVXlbVsn6TIW?si=1fc76f8e7d514dfb Joel, B. 1974. Street life Serenader https://open.spotify.com/track/5tFUPBJqdtWjxCdBtqDwRf?si=9220f9874f214a6fJoel, B. 1977. Scenes from an Italian Restaurant.https://open.spotify.com/track/3utq2FgD1pkmIoaWfjXWAU?si=b6c0eeaa07fe4348Hunter/Garcia. 1971. Not Fade Away/Goin Down the Road Grateful Dead.https://open.spotify.com/track/3JZeVTm20lmT0wTui4oWh9?si=408821e635784759

“If you build it, they will come,” says John Wood of Baylor's 508,000‑square‑foot Baylor Sciences Building (BSB), an elite facility that houses Baylor's Department of Chemistry and Biochemistry alongside other science disciplines. A nationally recognized leader in organic synthesis whose work contributes to drug leads for cancer and numerous other diseases, Wood speaks from inside his BSB research lab about his department's continued growth—ranging from advances in understanding disease to expanding work in materials chemistry and beyond. He also reflects on the collaborative environment the BSB enables and shares why mentorship remains a passion as he and his colleagues nurture resilient, creative future problem‑solvers.

ReferencesScientific Reports 2021 volume 11, Article number: 16512Front. Oncol.2017. 26 November Vol7.Cell Death & Disease 2022. volume 13,Article number: 444Guerra, DJ. 2026. Unpublished LecturesMozart, WA. 1784. Serenade No. 10 for winds in B-flat major, "Gran Partita," K. 361https://music.youtube.com/watch?v=k0ig72-rj0s&si=VykW0x8UnOFGq0-e

In this episode, Giovanni Piedimonte, MD, FAAP, FCCP, Professor of Pediatrics, Biochemistry, and Molecular Biology at Tulane University School of Medicine, discusses how artificial intelligence is transforming research, clinical care, and academic medicine. He also discusses the risks, ethical challenges, and workforce implications health systems must prepare for as AI adoption accelerates.

It's gator time, folks! It seems like we should've already covered this topic, but, nope, this is our first ever episode on the American Alligator (Alligator mississippiensis), and we've got two ringers to help: Daniel returns (our Field Guide host who moved to Florida last year) and he's joined by his mentor in all things swamp-related, Chip Campbell. Chip spent twenty years running Okefenokee Adventures, leading interpretive tours in the Okefenokee National Wildlife Refuge, and his knowledge of alligator natural history and ecology runs deep.Thanks to our Patrons, this episode is also an on-the-road joint. The guys are deep in the Florida Everglades on a multi-day paddling trip, and they take a break at camp to talk with Chip about all things alligator — with a special focus on separating gator myths from reality.And, unfortunately for those of you crushing on Steve, this one's 100% Steve-free.This episode was recorded on Dec. 31, 2025 at Watson's Place campsite in Everglades National Park.Episode Notes and LinksAlligators, metabolism, and the “dog comparison”During the episode, Chip mentioned a study suggesting that several alligators could be maintained on roughly the same caloric intake as a single dog. We were not able to locate a study that makes that specific numerical comparison. However, the underlying idea is strongly supported by research on alligator physiology: American alligators have extremely low metabolic rates compared to warm-blooded mammals because they are ectothermic and do not spend energy maintaining body temperature. Classic physiological work shows that adult alligators can have daily energy expenditures that are only a small fraction of those of similarly sized mammals, making informal comparisons like this directionally accurate even if the exact ratio is anecdotal rather than experimental. Source: Coulson, R. A. (1989). Biochemistry and physiology of alligator metabolism in vivo. Integrative and Comparative Biology, 29(3), 921–934. https://doi.org/10.1093/icb/29.3.921Freshwater “sipping” — the study behind the observation The behavior Chip describes is documented in a study by Nifong and Lowers, which examined how coastal alligators use estuarine habitats. The authors note that after heavy rainfall, a thin layer of freshwater can temporarily sit on top of saltier water, and alligators will take advantage of this by drinking from the surface. This helps them manage hydration and salt balance in brackish environments, despite lacking the salt-excreting glands found in crocodiles. Source: Nifong, J. C., & Lowers, R. H. (2017). Reciprocal intraguild predation between Alligator mississippiensis and elasmobranchs in the southeastern United States. Southeastern Naturalist, 16(3), 383–396.Alligator growth vs. ageChip addressed the myth that alligators continue to grow throughout their life. Echoing what he reported, research on American alligators shows that although hatchlings and juveniles grow rapidly, their rate of growth slows substantially as they get older, and studies indicate they reach near-maximum body size well before the end of their lives. Long-term data suggest many alligators stop adding significant length by roughly 25–35 years of age, and more recent work has revised the classic idea of indefinite growth toward a pattern of determinate growth with a growth plateau in adulthood. Human harvest of alligators in LouisianaAs Chip said, Louisiana supports the largest wild harvest program for the American alligator in the United States, with more than 2,000 licensed hunters routinely harvesting an estimated 30,000–35,000 wild alligators annually under a regulated tagging system. In contrast, other states such as Florida have had regulated harvest programs with substantially lower annual take.” Sources: Joanen et al. (2021), Evaluation of Effects of Harvest on Alligator Populations in Louisiana, Journal of Wildlife Management; Louisiana Department of Wildlife and Fisheries Alligator Annual Report (2019–2020); Hines (SEAFWA) status report on Florida alligators.Fatal Alligator AttacksIn this episode, Chip discusses the history of fatal alligator-human conflicts, highlighting the 1973 Sharon Holmes incident as the first "fully confirmed" fatal attack in modern records. While the Holmes incident is often cited as the definitive first case, there was an earlier death that some consider to be the first modern fatality. Historical records show why Chip's reference to the Holmes case being the first “fully confirmed” case is accurate:Sharon Holmes (1973): On August 16, 1973, 16-year-old Sharon Holmes was killed while swimming at Oscar Scherer State Park. This is widely cited as the first fully confirmed fatality because of the absolute nature of the evidence: the attack was witnessed by bystanders, and a subsequent necropsy of the 11-foot 3-inch alligator found conclusive physical remains. This event marked a turning point in how state agencies, like the Florida Fish and Wildlife Conservation Commission (FWC), tracked and verified alligator-related deaths.Allen Rice (1957): While most official FWC lists of fatal attacks begin in 1973, the 1957 death of 9-year-old Allen Rice in Eau Gallie is often mentioned as an earlier case. However, it is technically categorized as presumed. Rice went missing while fishing, and though his body was recovered with injuries consistent with an alligator and a large gator was seen nearby, there were no direct witnesses to the strike. Sponsors and Ways to Support UsGumleaf Boots, USA (free shipping for patrons)Thank you to Always Wandering Art (Website and Etsy Shop) for providing the artwork for this and many of our episodes.Support us on Patreon.Works CitedCoulson, R. A. (1989). Biochemistry and physiology of alligator metabolism in vivo. Integrative and Comparative Biology, 29(3), 921–934. https://doi.org/10.1093/icb/29.3.921James C. Nifong & Russell H. Lowers (2017). Reciprocal Intraguild Predation between American Alligator (Alligator mississippiensis) and Elasmobranchii in the Southeastern United States. Southeastern Naturalist 16(3): 383–396.Joanen et al. (2021), Evaluation of Effects of Harvest on Alligator Populations in Louisiana, Journal of Wildlife Management; Louisiana Department of Wildlife and Fisheries Alligator Annual Report (2019–2020); Hines (SEAFWA) status report on Florida alligators.McIlhenny, E.A. (1935) The Alligator's Life History. Boston: The Christopher Publishing House.Photo CreditThanks again Always Wandering Art (Website and Etsy Shop) for the amazing gator painting!

Dr. Jessica Rose, PhD, MSc, BSc, is a Senior Fellow specializing in Computational Biology from Canada. She holds a Bachelor's Degree in applied mathematics and a master's degree in Immunology from Memorial University of Newfoundland, and a PhD in Computational Biology from Bar Ilan University. Dr. Rose has completed two post-doctoral degrees in Molecular Biology from the Hebrew University of Jerusalem, and in Biochemistry from the Technion Institute of Technology. She is best known for her contributions to public health and safety related to the COVID-19 injectable products, and her analyses of pharmacovigilance databases like VAERS. In this episode, Drs. Brian and Jessica talk about… (00:00) Intro (04:57) Dr. Jessica's upbringing, personality, and scientific pursuits (09:41) Covid vaccines, natural immunity, and bodily autonomy of individuals (19:50) The research of Kevin McKernan on DNA in vials of COVID-19 vaccines (27:39) The composition and production of Covid mRNA vaccines (33:04) National health regulation agencies and Covid vaccine DNA contamination (35:54) Lipid nanoparticles in mRNA vaccines and how they impact human health (44:22) Vaccine injuries due to spike protein proliferation and how the spike protein ruins the human immune system (54:38) Spike protein detox therapies (01:01:12) Fascia release (01:03:07) Cholesterol, gal bladder health, and nutrition (01:07:54) Fasting, autophogy, and the microbiome (01:11:33) Peer review and post-peer review attacks on valid research (01:21:53) Outro   For more information, please see the links below. Thank you for listening!   Links:   Resources Mentioned in this Episode: Jules Horn (Fascia Release): https://www.youtube.com/@Jules_horn Science Guardians (post-peer review group): https://x.com/SciGuardians   Dr. Jessica Rose: Research: https://www.researchgate.net/profile/Jessica-Rose-24 Why does DNA remain in vials of COVID-19 mRNA Shots?: https://rumble.com/v74rdvs-why-does-dna-remain-in-vials-of-covid-19-mrna-shots.html What Jessica Rose Knows: Dr. Jessica Rose on DarkHorse: https://rumble.com/v5q0zl8-what-jessica-rose-knows-dr.-jessica-rose-on-darkhorse.html   Dr. Brian Lenzkes:  Arizona Metabolic Health: https://arizonametabolichealth.com/ Low Carb MD Podcast: https://www.lowcarbmd.com/   HLTH Code: HLTH Code Promo Code: METHEALTH • • HLTH Code Website: https://gethlth.com