Podcasts about Biochemistry

ReferencesCell Death Dis. 2021 Sep 13;12(9):847.Theranostics. 2020 Jul 9;10(18):8315–8342.Int.J. Mol. Sci. 2024, 25(21), 11469Guerra, DJ.2026.Unpublished Lectures.Capaldi/Winwood.1967. 40,000 Headmen. Traffichttps://open.spotify.com/track/5YAPlTgnNDKmagJBccKaeR?si=e04f0dab65df46f4Leach, Donovan. Var by Duane Allman. 1967/1971. . Mountain Jam Live Allman Brothers. https://music.youtube.com/watch?v=5-3L1MFBKZY&si=_59ldBfIMhcfrtCC

Today, on Karl and Crew, we kicked off our weekly theme, “Chivalry.” Dr. Fazale Rana, also known as Dr. Fuz, joined us to discuss how biochemistry points to God’s design, explaining that discoveries in DNA and the unique human capacities for altruism, empathy, and chivalry reflect what it means to be made in the image of God. Dr. Fuz is the President, CEO, and Senior Scholar at Reasons to Believe, a non-profit that focuses on revealing God in science. Next, Seth Troutt joined us to talk about authentic masculinity, explaining how men can reject counterfeits such as passivity and toxic masculinity by pursuing godly character, Christlike responsibility, and biblical chivalry. Seth is the Teaching Pastor at Ironwood Church in the Phoenix metro area and author of “Authentic Masculinity: Leaving Behind the Counterfeits for God’s Design.” We then had Hutz Hertzberg join us to talk about the growing hunger for Christ-centered education, explaining why parents are rethinking their children’s schooling and how classical Christian education offers an alternative rooted in biblical truth. Hutz is the chairman at Hope in Truth and currently the Chief Education Officer of Turning Point USA’s education arm, Turning Point Education. You can hear the highlights of today’s program on the Karl and Crew Showcast. If you're looking to hear a particular segment from the show, look at the following time stamps:Dr. Fuz Rana [ 20:17 ]Seth Troutt [ 33:57 ]Hutz Hetzberg [ 11:49 ]Donate to Moody Radio: http://moodyradio.org/donateto/morningshowSee omnystudio.com/listener for privacy information.

ReferencesInt.J. Mol. Sci. 2024, 25(21), 11469Scientific Reports 2016. volume 6, Article number: 28633 Guerra, DJ.2026. Unpublished LecturesSchubert, F. 1822. Symphony 8 in B Minor. D.759.Unfinishedhttps://music.youtube.com/watch?v=3tisvEpblig&si=Muk_sMfUKhgnB6KV

Today, on Karl and Crew, we kicked off our weekly theme, “Chivalry.” Dr. Fazale Rana, also known as Dr. Fuz, joined us to discuss how biochemistry points to God’s design, explaining that discoveries in DNA and the unique human capacities for altruism, empathy, and chivalry reflect what it means to be made in the image of God. Dr. Fuz is the President, CEO, and Senior Scholar at Reasons to Believe, a non-profit that focuses on revealing God in science. Next, Seth Troutt joined us to talk about authentic masculinity, explaining how men can reject counterfeits such as passivity and toxic masculinity by pursuing godly character, Christlike responsibility, and biblical chivalry. Seth is the Teaching Pastor at Ironwood Church in the Phoenix metro area and author of “Authentic Masculinity: Leaving Behind the Counterfeits for God’s Design.” We then had Hutz Hertzberg join us to talk about the growing hunger for Christ-centered education, explaining why parents are rethinking their children’s schooling and how classical Christian education offers an alternative rooted in biblical truth. Hutz is the chairman at Hope in Truth and currently the Chief Education Officer of Turning Point USA’s education arm, Turning Point Education. You can hear the highlights of today’s program on the Karl and Crew Showcast. If you're looking to hear a particular segment from the show, look at the following time stamps:Dr. Fuz Rana [ 20:17 ]Seth Troutt [ 33:57 ]Hutz Hetzberg [ 11:49 ]Donate to Moody Radio: http://moodyradio.org/donateto/morningshowSee omnystudio.com/listener for privacy information.

ReferencesJ Clin Invest. 2022;132(23):e152868Int.J. Mol. Sci. 2024, 25(21), 11469 PLoS One 2014 Nov 25;9(11):e113939. Guerra,DJ.2026.Unpublished LecturesLennon/McCartney. 1964 Twist and Shouthttps://open.spotify.com/track/5ZBeML7Lf3FMEVviTyvi8l?si=ba313e3affec403b

Send us Fan MailKyle Peche became severely ill at the age of 18, when people should be filled with energy and good health. He was experiencing extreme brain fog, debilitating fatigue, severe constipation, GI issues, joint pain, skin rashes, and dozens of other symptoms. After many years of obsessive research, he finally found his way to health through systematic, step-by-step detoxification & Mineral-Balancing.Mineral Balancing is a holistic healing science that heals most ailments without the use of drugs. It uses Hair Tissue Mineral Analysis (HTMA) as a compass, which guides directions regarding precise supplement, detoxification, diet, and lifestyle recommendations based on the HTMA that move the body towards more balanced biochemistry, which maximizes the body's cellular energy. The body in turn heals itself, which causes not only elimination of symptoms, but also better quality of life!With a passion ignited from his own suffering, Kyle has now coached hundreds of people to higher health through proper full body detoxification & cellular rejuvenation.Find Kyle at-https://www.jyotimineralbalancing.com/IG- @kyle_pecheYT- @Jyoti Mineral BalancingTHE REJUVINATION ROADMAP MASTERCLASS! Sign up here for FREE!https://www.jyotimineralbalancing.com/masterclass-sign-upFind Boundless Body at-myboundlessbody.comBook a session with us here! 

Your gastrointestinal tract is home to hundreds of bacterial species that play essential roles in digestion and metabolism. As this field of research expands it is becoming increasingly clear that these microbes influence systems beyond the gut: they can even impact brain functioning. These effects were once thought to occur indirectly over the span of minutes to hours through complex chemical signaling pathways. Over the past 15 years, however, scientists have discovered that gut bacteria can communicate directly with the brain via the nervous system, transmitting signals in a matter of seconds and reshaping how we understand the gut–brain axis. This week, we're joined by Kevin Rice, a fourth-year PhD candidate in the Department of Microbiology, co-advised by Dr. Maude David and Dr. Kenton Hokanson. Kevin's research focuses on how human gut cells interact with neurons and the role that the microbiome may play in influencing neurodevelopmental disorders. Through his work across both Microbiology and Biochemistry & Biophysics, he combines computational approaches with neuroscience techniques to better understand the big impact our microbial communities can have on human health. Tune in this Sunday, June 7th at 7 PM to hear Kevin talk about how pursuing scientific questions has shaped his perspective on what constitutes a worthwhile career and the implications of his work in understanding neurodevelopmental disorders.

references Front Immunol . 2019 May 31:10:1187Cells 2020, 9(1), 228Guerra, DJ.2026. unpublished Lectures.Schubert, F 1826. (June). Quartet in G Major. D887.https://music.youtube.com/watch?v=9One__hAjrI&si=spHOFmdbCmMWdqp1

ReferencesInt J Mol Sci. 2019 Mar; 20(5): 1223Guerra, DJ. 2026. Unpublished LecturesMemphis Slim/Eric Clapton. 1972. Steppin Out. Live Cream Vol IIhttps://music.youtube.com/watch?v=XAB6K-5XWU4&si=NYtJSKh9lvYhxu8T

Bruce Lipton famously said that The Matrix is more a documentary than a movie. And that to be truly free, humans must escape the subconscious programming they have been subjected to since childhood. In this episode from the Align Podcast, Bruce Lipton explains why fear may be at the root of most modern illness, how beliefs shape biology through epigenetics, and why 95% of our lives are driven by subconscious programs. We also explore self-love, stress, healing, personal responsibility, psychedelics, consciousness, and practical ways to reprogram the mind. ALIGN PODCAST EPISODE #598 IS SPONSORED BY:

ReferencesNature Reviews Genetics 2019. volume 20, pages 657–674Int.J. Mol. Sci. 2014, 15, 16848-16884Nat Cell Biol. 2019 Mar; 21(3): 397–407.Cell. 2006. Volume 126, Issue 3, 11 August Pages 503-514Circ Res. 2018 Sep 14; 123(7): 868–885. DNA Repair (Amst) 2019 Nov:83:102640Guerra,DJ.2026. Unpublished LecturesSchubert, F. 1826. Symphony 9 in C Major D.944https://music.youtube.com/watch?v=TPpvJnwf5BU&si=pkO5rekCvtw9AHNv

References eLife 2020;9:e55828 DOI:10.7554/eLife.55828Cell Death Discovery2024.  10, Article number: 231 Int J Mol Sci. 2017 Sep 15;18(9):1979Guerra, DJ.2026. Unpublished lecturesHunter/Lesh 1970. Box of Rainhttps://open.spotify.com/track/7x2xjJV3YAPeLQJ7u3Kjet?si=37646e5c42584619

ReferencesJ Pineal Res. 2017 Sep 6;63(4):e12440Nature Reviews | Cancer Reviews2019. 19 | AUGUST 2019 :pp. 439J Exp Clin Cancer Res 2022. 41, 268.Front. Genet., 11 March 2015 Sec. Cancer Genetics Volume 6 - 2015 | https://doi.org/10.3389/fgene.2015.00094 Pathol Oncol Res 2022 Aug 19:28:1610401Guerra, DJ.2026.Unpublished LecturesPorter, C. I1944. Love You Bing Crosbyhttps://music.youtube.com/watch?v=U2Ehu42-mik&si=tkpg8dJxk2TdBvQPAhlert and Turk. 1928. 1944 I'll Get By. Harry James and Orchestrahttps://music.youtube.com/watch?v=8KhO3g5kY0c&si=fXWDc4ZheJ658A1xBeethoven, LV. 1804. Symphony V. C Minor Op 67https://music.youtube.com/watch?v=q_kw904K2bw&si=qDRCnK5UVDi1-9w2

ReferenceseLife 2020;9:e55828 DOI:10.7554/eLife.55828 Int J Mol Sci 2017 Sep 15;18(9):1979 Genes (Basel) 2021 Aug 31;12(9):1370Guerra, DJ.2026. Unpublished LecturesDylan, B. 1964. My Back Pages. Byrdshttps://open.spotify.com/track/1yexhSDARSLVvRCBU3wDAm?si=56d728e0cdcd42a4Winwood/Capaldi, 1970. Empty Pages. Traffichttps://open.spotify.com/track/4UhB17vQsTP0qM9grc4ZUi?si=636948e5ac7f457eSeger,B. 1972. Turn the Page.https://open.spotify.com/track/3P2XAL8UpPBM3nfvuEjHHE?si=47130e77f3ae4729

ReferencesOpen Heart. 2022 Dec 15;9(2):e002171.J Pineal Res. 2017 Sep6;63(4):e12440Int J Mol Sci. 2022 Feb 8;23(3):1905Guerra, DJ. 2026 Unpublished LecturesMozart, WA.1785/1786. Piano Concerti 22&23 . E flat and A major K.282 and 488,https://music.youtube.com/playlist?list=OLAK5uy_lkoFk_2RmT1POq5-0idPoWwAVX5U_yOAk&si=p-m9VoElWiZRURrS

Jessica has had a cool path in biochemistry, with work in both academia and industry, as well as an internship at the National Institutes of Health. She is the Director of New Product Development at LCG Clinical Diagnostics, where she oversees the R&D department. In addition to her work at LCG Clinical Diagnostics, Jessica has been an enthusiastic volunteer for both the Maine Science Festival and the Bioscience Association of Maine's Bioscience Day. This conversation was recorded in May 2026. ~~~~~The Maine Science Podcast is a production of the Maine Discovery Museum. It is recorded at Discovery Studios, at the Maine Discovery Museum, in Bangor, ME. The Maine Science Podcast is hosted and executive produced by Kate Dickerson; edited and produced by Scott Loiselle. The Discover Maine theme was composed and performed by Nick Parker. To support our work: https://www.mainediscoverymuseum.org/donate. Find us online:Maine Discovery MuseumMaine Discovery Museum on social media: Facebook Instagram LinkedIn Bluesky YouTubeMaine Science Podcast on social media: Facebook Instagram YouTubeMaine Science Festival on social media: Facebook Instagram LinkedIn YouTube© 2026 Maine Discovery Museum

Severe seizures, nonstop crying, and an exaggerated startle reflex marked the beginning of Elliott's journey with molybdenum cofactor deficiency type A (MOCD type A), an ultra-rare inherited metabolic disorder that can cause devastating neurological damage shortly after birth. After initially being told that Elliott would likely not survive to school age, his family was offered access to an experimental treatment that changed the course of his life. In this episode of On Rare, David Rintell, Head of Patient Advocacy at BridgeBio, and Mandy Rohrig, Senior Director of Patient Advocacy at BridgeBio, travel to England to meet Elliott and his family and hear how they navigated diagnosis, uncertainty, and hope after already experiencing the heartbreaking loss of another child. Geoff and Lucy, Elliott's parents, reflect on the emotional toll of diagnosis, the realities of managing complex medical care at home, and the joy of watching Elliott grow, attend mainstream school, and live life alongside his siblings. Their story highlights the importance of early diagnosis, caregiver resilience, and the life-changing impact of treatment for rare disease families. Dr. Günter Schwarz, Professor of Biochemistry at the University of Cologne and a leading expert in MOCD, provides a medical overview of the condition. MOCD is a rare inherited metabolic disorder caused by the body's inability to produce molybdenum cofactor, which is required for several critical enzymes to function properly. Without it, toxic sulfite builds up in the body, particularly in the brain, leading to severe seizures, neurological injury, and often early death. Dr. Schwarz explains how the condition is inherited, why symptoms begin so early in life, and how targeted treatment can dramatically alter outcomes when started quickly after diagnosis.

ReferencesAging (Albany NY). 2019 Jan 15; 11(1):73–88.Int J Mol Sci. 2022 Apr; 23(7): 4009Lipids 2022. Volume57,Issue3May Pages 183-195Guerra, DJ. 2026. Unpublished LecturesBeethoven LV. 1804. Appassionato Sonata No. 23. Op.57https://music.youtube.com/watch?v=0Ak_7tTxZrk&si=Cp5xQtTJytrKaPxpLennon/McCartney.1969. She's so Heavy. Beatles Abbey Road https://open.spotify.com/track/3Z25k4ZF6QENy2d9YatsM5?si=ffc68e8805a14de0

ReferencesInt. J. Mol. Sci. 2023, 24(4), 3120Cell Death & Differentiation 2021. v28, pages 3357–3370Neuropsychiatr Dis Treat. 2025 Sep 10;21:2035–2052. JACCCardiovasc Interv.2025 Apr 28;18(8):963-971Guerra, DJ.2026. Unpublished LecturesBiber, HIF.. 1674. Passagalia C.105https://music.youtube.com/watch?v=MohWMCmO3SE&si=1BjlIDO7HuI_GxaM Jagger/Richards. 1970 Wild Horses Rolling Stoneshttps://open.spotify.com/track/4M4Q3JLsUbyTkd5WHty1WB?si=81cc8e5c47d74958

ReferencesCell Death & Differentiation 2021.v28, pages 3357–3370JAAC.2025.Volume 13, Issue 12, December 102419Cell Metabolism.2024. 36.4.p839-856.Plato. 384. B.C. Euthydemus.Guerra, DJ.2026. Unpublished LecturesSimon, P. 1966. Sounds of Silence lp S&G.https://music.youtube.com/playlist?list=OLAK5uy_l1zPBX4IytOZWfqrKWceG__uYvGxPSWJ0&si=TadThwfgxwRq-IHi

ReferencesCell Metabolism 2024. Volume 36, Issue 4p839-856.e8April 02,JNeurosci.2012Dec 5;32(49):17909–17920.JACC Cardiovasc Interv. 2025 Apr 28;18(8):963-971Genes Dev. 2012 May 15;26(10):1070–1085.Nature Communications 2018. V 9, Article number: 1479 Guerra, DJ. 2026. Unpublished LecturesAnderson/Howe/Squire/Offord/Bruford/Wakeman. 1972.. You and I. Yeshttps://music.youtube.com/watch?v=HfssvCECiaA&si=48Gs_iJC5x3t8evF

This month, Mary met up with Dr. Beronda Montgomery, a plant biologist, writer, researcher and scholar. Dr. Montgomery works to understand how individuals perceive, respond to, and are affected by the environments in which they live. By investigating the response of photosynthetic organisms (i.e., plants and cyanobacteria) to external light cues, she is able to identify related roles for innovative leaders in human settings.After over 18 years at Michigan State University as a Foundation Professor in Biochemistry, Molecular Biology, Microbiology and Molecular Genetics, Beronda served as Vice President for Academic Affairs, Dean, and Professor of Biology at Grinnell College. In that time, she co-founded the annual Black Botanists Week. Then, since 2025, she's been the Sally Starling Seaver Fellow in Biological Sceinces with Radcliffe Harvard Institute.In this episode, Mary and Beronda speak of her most recent book, When Trees Testify. As Beronda writes, "Plants don't just passively provide. They also take action. They are masters of adaptation. They 'know' what and who they are, and they use this knowledge to make a way in the world. Plants are even capable of transformative behaviors that allow them to maximize their chances of survival in dynamic and sometimes unfriendly environments." Quite consistent with the rich spirit of her words here, this HILFH conversation was rich and enlivening. You can learn more about Beronda Montgomery by checking out her books, When Trees Testify and Lessons from Plants. Also spend some time with her website and the additional writings there. Let yourself be informed and inspired by Dr. Montgomery and the love of plants.MUSICRolled Ankles. Music by Nicholas Panek from PixabayMoonlight on Your Hands. Music by Mircea Iancu from PixabayEvening Strings. Music by DPStudioMusic from PixabayOriginal theme music composed and performed by Gary Ferguson.----HILFH is an educational project of Full Ecology. Check us out and let us hear from you.

ReferencesJACC Cardiovasc Interv.2025 Apr 28;18(8):963-971Handb Exp Pharmacol. 2014:222:129-56. American Journal of Physiology-Cell Physiology 2009 297:5, C1263-C1274 10.1152/ajpcell.00109Mol Biol Cell. 2014 Sep 15;25(18):2677–2681.Leuk Lymphoma. 2019 Jan 2;60(6):1557–1562Guerra, DJ.2026. Unpublished Lectures.Hunter/ Garcia. 1974. Cruel White Water. Tiger Rose lp. https://open.spotify.com/track/6IzZ1u1D2hW5cv6KPxaKcO?si=065029cd691247ca

ReferencesBarnie, Juliana.2025. The Impact of Estrogen Loss on CaveolinExpression and Cardiac Myocyte Remodeling in Ovariectomized Mice Following Chronic Sympathetic Stimulation" East Tennessee State University MS ThesisSeminars in Cell and Developmental Biology May 2019 98(4)Am J. Physiology/Cell Physioloy.2007.Volume 293, Issue 6Methods Mol Bio. 2006:332:181-91. Cells 2022, 11(23), 3850; Guerra, DJ. 2026. Unpublished Lectures.Capaldi/Winwood. 1971. Low Spark of High Hell Boys Traffic https://open.spotify.com/track/1yW6y8RufwB4WEAQeip0tx?si=6fd9c8119343492b Beethoven, LV. 1812. Symphony 7.in A major. OP 92. https://music.youtube.com/watch?v=Rd0HnxWm5CY&si=jrDwV4F6Cy6SUjA1

ReferencesCurr Cardiol Rev . 2009 May;5(2):105–111.Cell Prolif. 2021 Dec 22;55(1):e13167Int J Mol Sci. 2020 Aug 20;21(17):5989Life Sciences 2007. 30 January 800-812.80, Issue 8Biomedicine & Pharmacotherapy 2024. Volume 174 • Article 116563Guerra, DJ.2026. Unpublished LecturesSebastian, J. 1970. She's a Lady. Lovin' Spoonful.https://music.youtube.com/watch?v=xyFdzevDOHg&si=3Vj95GXjl2Jm1AVrJagger/Richards. 1967. Ruby Tuesday. Between the Buttons. lphttps://open.spotify.com/track/4hupcimlg3UBbW1kAQ6vrT?si=b121276a3d4f4c6fCorelli, A. 1680's. Twelve Violin Concerti Grosso. OP .6.https://music.youtube.com/watch?v=npCO_8zBl-8&si=Nooi_AJbNaHoCXc8

ReferencesFront. Oncol.2017. 24 Sept. vol7. 211.Circ Res. 2023 Feb 17;132(6):723–740EMBO J. 2023 Jan 13;42(4):e110620.Guerra, DJ. 2026. Unpublished LecturesNash, G. 1968. Teach Your Children CSNYhttps://music.youtube.com/watch?v=r72QF7JOQvw&si=FANpHvTEzozHjDe2Stills, S. 1967. Bluebird. Buffalo Springfield.https://music.youtube.com/watch?v=yKHY8MXgiz0&si=-GcugFbzT8oUwqAM

ReferencesDev Cell. 2023 Apr10;58(7):597-615.e10.CurrentBiology.2024. V.34, Issue 21pR1067-R1068November 04.RNA.2020 Aug;26(8):903–909Sci Rep. 2015. volume 5,Article number: 15292 SciRep. 2025 Jul 14;15(1):25389.Guerra, DJ.2026.Unpublished LecturesLennon/McCartney. 1967. Good Morning Good Morninghttps://open.spotify.com/track/0xIuNHHcKI1JDuBPlSwzb1?si=d9a84805b0144608Mozart, WA. 1785. The Haydn Quartets. Op 10.https://music.youtube.com/playlist?list=OLAK5uy_nFz2DrhfPWUriYaJw44iN4p4hBuem83Sc&si=j8s78fyUsC08bKTe

ReferencesJ Hum Evol.2022 Oct; 171: 103229. Am J Physiol Cell Physiol 2022. 322: C125–C135J Neuroinflammation. 2016 May16;13(1):109. doi:10.1186/s12974-016-0575-xPrz Menopauzalny. 2017 Jun; 16(2): 51–56Genes & Immunity2021. volume 22, pages 125–140 Dev Cell. 2023 Apr10;58(7):597-615.e10.Scientific Reports 2015.volume 5,Article number: 15292 Guerra, DJ.2026.Unpublished LecturesShubert, F Liszt,F. 1826. Standchen. Khatia.https://music.youtube.com/watch?v=9h35VSz2Kkc&si=28EA6Y5mCETviBmuJohn, E.1972. Mona Lisas and Mad Hatters,https://open.spotify.com/track/3AJVI8kKij8zD5YOR6HM9v?si=908210d10c594781

Mehlman Qbanks: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://qbanks.mehlmanmedical.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/mehlman_medical/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Main Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://mehlmanmedical.com/⁠

ReferencesJ of Cellular Physiology 2026 Volume241, Issue5 May e70190PPAR Res. 2010 Sep 26;2010:61208Guerra, DJ. 2026. Unpublished LecturesMiller, S. 1970. Steve Miller Band V.https://music.youtube.com/playlist?list=OLAK5uy_mMurbyyiMLz7bvTAJmI_j8sCs_e-NbvAM&si=U7RzDJWU9CtB_oCU

Lipoprotein(a) or Lp(a) is suddenly all the rage because several drug companies are working on medications to lower this previously resistant form of cholesterol. Almost entirely genetic, unaffected by diet or lifestyle, it has numerous studies linking it to heart disease and aortic valve calcification. But it may not be the ticking time bomb some influencers like to claim.   Become a supporter of our show today either on Patreon or through PayPal! Thank you! http://www.patreon.com/thebodyofevidence/ https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE   Email us your questions at thebodyofevidence@gmail.com.   Editor:    Robyn Flynn Theme music: “Fall of the Ocean Queen“ by Joseph Hackl Rod of Asclepius designed by Kamil J. Przybos Chris' book, Does Coffee Cause Cancer?: https://ecwpress.com/products/does-coffee-cause-cancer   Obviously, Chris is not your doctor (probably). This podcast is not medical advice for you; it is what we call information. References: The genetic nature of Lp(a) levels: https://pubmed.ncbi.nlm.nih.gov/1386087/ Prevalence of elevated Lp(a) in 500,000 US patients https://pubmed.ncbi.nlm.nih.gov/27659098/ Prevalence of elevated Lp(a) in 2.9 million Chinese adults https://pubmed.ncbi.nlm.nih.gov/40266173/ Prevalence of elevated Lp(a) in the INTERASPIRE study https://pubmed.ncbi.nlm.nih.gov/40436467/ Variation of Lp(a) by sex: https://pubmed.ncbi.nlm.nih.gov/27659098/ One of the many studies linking Lp(a) to cardiovascular disease https://pubmed.ncbi.nlm.nih.gov/33115266/ High Lp(a) and aortic stenosis: https://www.nejm.org/doi/full/10.1056/NEJMoa1109034 FH and Lp(a) https://pubmed.ncbi.nlm.nih.gov/32466883/ The ongoing Lp(a) trials https://familyheart.org/lpa-clinical-trials  

ReferencesFront. Endocrinol., 2019. 02 July Sec. Molecular and Structural Endocrinology Volume 10 -J Cell Physiol. 2026 May;241(5):e70190Thromb Haemost.2009 Sep;102(3):544–554.Guerra, DJ. 2026.Unpublished LecturesCahn and Heusen. 1957. All The Way Frank Sinatrahttps://open.spotify.com/track/7fanCwOck16J9MPJ3SR39P?si=df1d1051137648f4Dvorak, A. 1983. American String Quintet 3. E Flat Major OP.97https://music.youtube.com/watch?v=cip5TJ7H4jg&si=kOTQNlmy93LDJNvL

In this episode of Tiny Show and Tell Us, a listener asks: Could we still be carrying air from our very first breath? Deboki unpack's residual lung volume, gas exchange, and a forensic technique used to determine whether or not someone drowned. Then, the conversation turns to women's health and bleeding disorders after a listener shares their experience living with Von Willebrand disease — the most common bleeding disorder. Sam explores what the condition is, how it was discovered, why it disproportionately affects women, and how normalizing heavy, painful periods is not just frustrating but has serious medical consequences.Check out Pale Blue Pod here or wherever you get podcasts!We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of Medsider Radio, we sat down with Antony Odell, co-founder and CEO of Echopoint Medical.Echopoint is a London-based UCL spinout developing iKOr, an optical microcatheter for coronary diagnostics.Antony brings over 30 years of medtech experience across Johnson & Johnson, Fresenius, and Stryker, before transitioning into startups as CEO of Tayside Flow Technologies and Tissue Regenix. He holds a BSc in Physiology and Biochemistry.In this interview, Antony discusses translating academic IP into a commercial device, choosing early clinical sites to balance speed and learning, managing non-dilutive funding as a long-term discipline, and outlines the most important responsibilities of an early-stage medtech CEO.Before we dive into the discussion, I wanted to mention a few things:First, if you're into learning from medical device founders and CEOs and want to know when new interviews are live, head over to Medsider.com and sign up for our free newsletter.And if you're ready to level up your medtech game, you should check out Medsider Courses — 8-week masterclasses covering topics like fundraising, M&A and exit planning, design and development, clinical and regulatory strategy, and commercialization.These courses, featuring hard-earned lessons from elite medtech CEOs, can be purchased individually or come free with our All-Access Pass.If you'd rather read than listen, here's a link to the full interview with Antony Odell, which includes a link to ScottBot — an AI version of host Scott Nelson trained on every Medsider interview and playbook. Feel free to ask ScottBot any questions you'd like!KEY MOMENTS FROM THE INTERVIEW(03:06) - How Antony's career centered on translating clinical insights into commercial reality (05:54) - What Echopoint's iKOr does, and why 40% of cath lab patients leave without a diagnosis (12:13) - How Echopoint landed its first U.S. clinical site, and what that means for the company (13:48) - What to assess before spinning out an academic idea, and why clinician input is the first real test (20:14) - Why Echopoint chose Barts over typical sites for its first-in-human study (22:58) - How getting too close to one clinical site can lead to dangerous groupthink (30:54) - Why non-dilutive funding belongs on the board agenda permanently (39:54) - How CEOs should manage boards, control information flow, and avoid becoming a “glorified note-taker”

ReferencesGuerra, DJ.2026Sci.Signal.2019:26 Mar Vol.12, Issue 574, eaau2293

ReferencesGuerra, DJ. 2026. Unpublished lecturesSci Signal.2019.12.eaau2293

ReferencesCell Death & Differentiation 2023 v. 30, pages 1869–1885Cells. 2021 Jan 6;10(1):79Ecotoxicology and Environmental Safety 2024. Volume 282, 1 September 2024, 116679Front. Pharmacol., 2024. 04 December Sec. Experimental Pharmacology and Drug Discovery Volume 15 - Sci. Signal.  2019. 26 Mar Vol.12, Issue 574, eaau2293Guerra, DJ.2026. Unpublished Lectures Mydland and Barlowe. 1989. I Will Take You Home. Grateful Dead.https://open.spotify.com/track/1Q3AmIjEbPYemA6UkjUUu0?si=5014bc2c6ef74a65Mozart, WA 1791. The Magic Flute Operahttps://music.youtube.com/playlist?list=OLAK5uy_nCgjvGbOpaD5JFQLyxnlHwUBWx2xUuxjM&si=iMmA1zF6O0dzgE1h

Modern science has given us the ability to edit our genes, life-saving vaccines, and glimpse the origins of the universe. But is the same system holding itself back? Critics argue that the pressure to publish and fierce competition for funding rewards safe, incremental work over bold thinking. Others see a system still capable of paradigm-shifting discoveries — one where global collaborations and long-term thinking motivate scientists to pursue grand, ambitious ideas. Now we debate: Is the Scientific Enterprise Too Risk-Averse?  This debate was produced in partnership with the Stavros Niarchos Foundation (SNF) Agora Institute at Johns Hopkins University, as part of The Hopkins Forum series. Arguing Yes:  Tyler Cowen, Author of "The Great Stagnation"; Economics Professor at George Mason University; Founder of Emergent Ventures; Host of "Conversations with Tyler" podcast   Brandon Ogbunu, Computational Biologist; Associate Professor of Ecology and Evolutionary Biology at Yale University; Professor at the Santa Fe Institute  Arguing No:   Kate Biberdorf (“Kate the Chemist”), Professor for the Public Understanding of Science and the Department of Chemistry & Biochemistry at the University of Notre Dame; Science Entertainer  The Honorable Sethuraman Panchanathan, 15th Director of the National Science Foundation; University Professor of Technology and Innovation and Foundation Chair at Arizona State University  Emmy award-winning journalist John Donvan moderates  Join the conversation on Substack—share your perspective on this episode and subscribe to our weekly newsletter for curated insights from our debaters, moderators, and staff.  Follow us on YouTube, Instagram, LinkedIn, X, Facebook, and TikTok to stay connected with our mission and ongoing debates.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

ReferencesCell Mol Life Sci. 2022 Aug 5;79(8):468Atherosclerosis,2020. 315, e90-e91J Clin Invest. 2025;135(2):e185218.EXCLI J 2023;22:Doc334Cells. 2019 Mar; 8(3): 227.Guerra, DJ. 2026. Unpublished LecturesSimon, P. 1968 America Simon and Garfunkelhttps://open.spotify.com/track/6dfhF1BDGmhM69fnCb6wSC?si=de9fc46c7f354d1aLennon/McCartney.1969. Golden Slumbers/Carry that Weight/The End Beatles Abbey Road.https://music.youtube.com/watch?v=LjOl0fG72ZE&si=O60Nuj_pjt_Z8EscHaydn, M. 1770's. String Quartets P.116-124.https://open.spotify.com/album/0ZQ4mN9IFzGChy6dATIk5t?si=OmzbnclJQXaeg-03ifP7aw

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ReferencesVasc. Health Risk Manag. 2023.Feb 5,19.69.Guerra, DJ.2026. Unpublished lecturesPLoS Genet. 2019 Jul 25;15(7):e1008287Lesh/Peterson.1974.Unbroken Chain. Grateful Dead LFMH. https://open.spotify.com/track/0QT7prPZzXJKBYMVdWlE1Z?si=8ac25d38274f44c0

Dr. Deb Muth 00:03Welcome to Let’s Talk Wellness Now. I am your host, Dr. Deb.And today, I have the pleasure of meeting with Dr. James Greenblatt. I’ve known Dr. Greenblatt for a very long time. We, started lecturing together, gosh, over 15 years ago.And he is an amazing practitioner. Dr. Greenblatt is dual board certified in psychiatry and internationally recognized.as a pioneer in functional and integrative psychiatry. He’s widely regarded as the leading expert on the clinical application of low-dose lithium for mental health.Dr. Greenblatt has spent more than 30 years advancing precision medicine-based approaches that move beyond symptom management to address the root causes of mental illness.And after earning his medical degree at George Washington University.Dr. Greenblatt completed his psychiatry and residency there as a fellow in child and adolescent psychiatry.Joined John Hopkins Medical School, and he currently serves as an assistant clinical professor of Psychiatry at Tufts University. He is a prolific author. Dr. Greenblatt has written 9 books, including his newest book, Finally Hopeful. in… available in January of 2026. We can ask him about this today.And his bestsellers finally focused the breathwork, natural treatment plan for ADHD,Answers to anorexia, Functional and Integrative Medicine for Antidepressant withdrawal, and nutritional lithium, and Untold tale of Mineral and Transforms Lives, that heals the brain.He has founded, in 2019, the Psychiatry Redefined, a leading educational platform training clinicians worldwide in functional and integrative psychiatry. He is a sought-after international speaker. Dr. Greenblatt regularly lecturesOn nutritional psychiatry and the transformative role of functional medicine.I am super excited to have him here with us today. This is going to be a pleasure. You guys are going to love this conversation that we are going to have. And I am going to pick his brain today on functional and integrative psychology and psychiatry, and combining nutrition, biochemistry, and lifestyle with mental health care.I’m really, really happy to have Dr. Greenblatt with us, so I am going to bring him on, and we are going to have this amazing conversation with my friend.Welcome back to Let’s Talk Wellness Now. I’m your host, Dr. Deb, and I have with me Dr. James Greenblatt, who I have followed for… we were just chatting about this for over 20 years.He is amazing in what he is doing, and we are going to have this conversation today about integrative psychiatry and the future of mental health. So, welcome to the show, Dr. Greenblatt. James greenblatt md 03:20Thank you, Dips, good to be with you. Dr. Deb Muth 03:22Now, you’ve been pioneering this integrative psychiatry for decades. What really inspired you to bridge nutrition and psychiatry long before it’s become mainstream? James greenblatt md 03:35You know, I developed an interest in college, you know, studying nutrition, and then I remember writing papers on orthomolecular psychiatry, high dose, vitamin B3 for schizophrenia.So, I really did not think I’d be a psychiatrist. I wanted to be a pediatrician when I went to medical school, but, just early interest in nutrition and brain function.And it’s been my career now for 30-plus years. Dr. Deb Muth 04:05Wow. Can you define what integrative psychiatry actually means, and how it’s different from traditional psychiatry for most people who wouldn’t be familiar with that term? James greenblatt md 04:17Sure, I mean, I have to add the word functional as well. I mean, I think, you know, I call myself a functional psychiatrist, but for most of my career, and every book, and everything I did, I would have to use words like functional and integrative.Medicine for mental illness. And, you know, I define integrative medicine as the… Adjunctive lifestyle, mindfulness. And diet, sleep, and exercise. Dr. Deb Muth 04:46Mmm. James greenblatt md 04:46And I kind of use the term functional for kind of a deeper root cause dive, looking at nutritional deficiencies, looking at hormones, looking at genetics. And, you know, to treat patients with mental health challenges, we need both integrative and functional medicine. Dr. Deb Muth 05:05That’s awesome. You know, in our integrative space, we often kind of joke that there’s no such thing as a Prozac deficiency, right? Can you explain to our listeners how nutrient deficiencies, gut health, or inflammation can play a role in mental illness? James greenblatt md 05:23Sure, I mean, I think the most importantBeginning of this conversation would be that, you know, 10 people with depression, there might be 10 different underlying factors. Dr. Deb Muth 05:35Yeah. James greenblatt md 05:35And we do know that there’s not an antidepressant deficiency, so we have to look deeper. And… and that’s,just different than our current psychiatry model, where it’s just symptomatic-based medicine. Everyone who’s depressed. It’s an antidepressant.And by looking at functional integrative medicine, we’re looking at B12 and vitamin D and zinc and magnesium. We’re looking at hormones, we’re looking at the gut, and we’re trying to determine what might be either causing or contributing to that person’s depression. Dr. Deb Muth 06:10Is there a particular, flavor that you see more commonly with others, like depression versus anxiety versus bipolar. Is there a particular underlying factor that you see more commonly than others? James greenblatt md 06:27Well, the short answer is no, and that’s why this work takes time, because you have to think.You know, every patient that walks in the office is different. I mean, I think the overarching umbrella is nutritional deficiencies, you know, whether… regardless of weight, regardless of diet. I mean, I have people coming in who’ve been eating…You know, these ketogenic or paleo diets, you know, perfect organic foods, and are profoundly nutritionally deficient.So I think nutritional deficiencies would be number one, and then, you know, the whole host of, you know, infections and hormone problems and inflammatory issues related to celiac disease is really common in the mental health space that’s ignored. Dr. Deb Muth 07:14Yeah. Celiac disease is really not paid attention too much, other than thinking that it’s damaging the gut. They don’t really think about all the other aspects of the body that are being affected by the gut not being able to absorb the nutrients properly and then utilize them properly. It’s really sad. James greenblatt md 07:34we find out… and there’s research to support it. That’s the tragedy. This is not something, as clinicians, that we found. We have many, many years of research showing high rates of anxiety and depression, you know, amongst those with, celiac disorder because of this chronic malnutrition, and many patients present without any GI symptoms, just mental health complaints, but nobody’s looking at celiac. Dr. Deb Muth 08:02Yeah. You know, I’m sure there’s people that are listening to us thinking, there’s no way thatEverybody who’s depressed or anxious has a nutritional deficiency. When we’re… live in a country where there’s so much abundance of food, and the obesity rates are high, and most people are very plump, how could those people be deficient in nutrients? What do you say to people who think like that? James greenblatt md 08:28Yeah, I mean, I think that, you know, we have, what’s called high caloric malnutrition, so regardless of weight, I would say the vast majority of patients with a mental health issue I would say my best guess would be 90-plus percent. Dr. Deb Muth 08:47Wow. James greenblatt md 08:47We would find nutritional deficiencies. Dr. Deb Muth 08:51And part of this, we’ve discovered, is genetics. James greenblatt md 08:56People having, kind of, genetic needs for Higher amounts of certain micronutrients. Some of it is just the kinds of foods people are eating. The kind of ultra-processed food actually strips the body of micronutrients. So, it is just so common, and many of these tests are pretty simple that your primary care doctor could do in the office. Dr. Deb Muth 09:22So, traditional labs can identify some of these nutritional deficiencies. They don’t necessarily have to invest thousands of dollars in advanced nutrient testing to find these things out. James greenblatt md 09:35Absolutely. I mean, I think, you know, oftentimes when we’re working with a patient who has failed traditional psychiatric treatment, we do need some functional, testing, but I’m quite convinced we could change the trajectory of our mental health epidemic in this country by some labs that are covered by every insurance company on the planet. Like, people think of vitamin D as, you know, building bones or immune function.It has dramatic relationships to mental health problems, demonstrated over 30 years of research. So vitamin D and B12 and folate, all simple blood tests that are covered by all health insurances. Dr. Deb Muth 10:18You know, with the change of genetics, MTHFR is so popularly known these days. It’s probably the most popular genetic mutation that people know of.And in the mental health space, it plays a significant role as well in that absorption of B12 and folate. How do you look at MTHFR mutation with inside the mental health world? James greenblatt md 10:43Well, I think it’s, It’s critical, it’s required on every patient that I see, and I’ve been, known to say it would be considered malpractice for psychiatrists not to test for the MTHFR gene. Because most of my career, I’ve spent working in inpatient psychiatric hospitals and residential. So seeing those individuals that have failed outpatient treatment, so really struggling.And one of the most common things I’ve been seeing for 30 years are those psychiatric patients not responsive to traditional treatment. oftentimes have one of the more significant MTHFR variants. And so we started doing the testing in the hospital, and they came back with these you know, variants and treated with folate, the medicines worked better, and their depression got better. It is simple. And essential. So, the integrative community, our community is aware of it, but our conventional psychiatrists are not testing for MTHFR. Dr. Deb Muth 11:50Yeah, it’s so sad, isn’t it? Because it’s such a simple test, and can make such a big difference in people’s lives. I know even in the OBGYN community, we’re not looking at MTHFR, and yet we’re giving women all this folic acid that many of them might not be able to actually utilize.And we’re… in my opinion, we’re doing a disservice to those women and the children that are being born to them for that. James greenblatt md 12:15Yeah, no, it’s frustrating, when there are clear, simple, treatment interventions that could make major difference in people’s lives that are just not incorporated into, kind of, routine treatment models. Dr. Deb Muth 12:31How come we see some people with MTHFR mutations, or gene mutations, have depression and anxiety that is so severe, and then other people seem to have absolutely no problems with mental health at all, and they have a similar profile? James greenblatt md 12:47Yeah, I mean, that’s just a great example, as, you know, genes aren’t our destiny, it’s just kind of a vulnerability.And, you know, we actually, when we were in the hospital, we tested, you know. hundreds of people and staff as well. And, you know, people are going to be lived to 100 and have these very vulnerable MTHFR genes. So it’s not the genes, it’s… I call it that genetic-environmental dance. So if we add… that genetic vulnerability, and maybe we add a, you know, a Lyme infection, or a chronic stress, or a B12 deficiency, or celiac, or we could list a hundred things, stress and inflammation probably being the most significant. With that genetic vulnerability, that’s where, you know, the implications of treatment come more defined. Dr. Deb Muth 13:45Yeah. What do you think the role of trauma plays in all of this, too, with the genetics? Do you think that trauma that people are living with today makes a big impact on their genes and how their genes are being turned on or off? James greenblatt md 14:01Yeah, I mean, we know trauma is kind of, you know, sets the stage for so much psychiatric illness. I think in my… Community of mental health professionals. we kind of use the trauma as an excuse to not think of the biology. And trauma… Affects the biology. Dr. Deb Muth 14:21So… James greenblatt md 14:22without negating the past trauma or current trauma, we still need to dig deep into the B12 and MTHFR and vitamin D. But… the trauma does affect the expression of certain genes. It also ex… we see a lot of, nutritional deficiencies after trauma due to poor digestion, because the Digestive enzymes and the hydrochloric acid kind of just shut down. And so, again, eating great food, but not absorbing these micronutrients. So I’ve seen that years after trauma. Dr. Deb Muth 14:5Yeah, it’s really hard. I’ve worked with Dr. Mark Gordon, and he does a lot of trauma work for veterans, and he focuses a lot on the hormones that get affected because of the brain trauma and the head trauma that people experience in combat. Or the repetitive shot firings and things like that, and how it correlates to anxiety. And then just balancing out some of those hormones can make a significant difference for them, and he’s actually been tracking the reduction of some of the hormones as a result of those traumas. Have you seen similar things like that with mental health and hormones? James greenblatt md 15:36Not… I haven’t made that direct correlation, but what we see when we evaluate somebody with trauma is just, you know, a kind of very wide range of metabolic abnormalities from Hormonal, to insulin resistance, to nutrient deficiencies, again, that aren’t dietary related. Dr. Deb Muth 15:57So… James greenblatt md 15:58Definitely, somehow, some path from the trauma. Dr. Deb Muth 16:03Yeah. If you had to choose your most favorite cutting-edge research or biomarker that you’re most excited about right now in the world of nutritional psychology or psychiatry, what would that be? James greenblatt md 16:19Well, you know, I counted as 250 that we look at when I evaluate a site patient, but there’s one… That is so simple, and has such profound implications, and that’s looking at levels of cryptopyrrol in the urine. Dr. Deb Muth 16:36Oh, yeah. James greenblatt md 16:37urine test. It measures this, molecule, a pyrole derivative, and Most of us would have normal levels. And if it’s elevated, It is, it’s likely a genetic vulnerability, but this, cryptopyrrol just binds B6 and zinc. So you have this tremendous deficiency of B6 and zinc. And elevated cryptopyril is always associated with psychiatric symptoms, usually anxiety, but we’ve seen depression and panic and even paranoia. And it’s simple to treat. We’re talking about, you know, pennies a day, B6 and zinc. Dr. Deb Muth 17:20The marker comes down. James greenblatt md 17:23And symptoms improve. I mean, it is really stunning and dramatic. Dr. Deb Muth 17:28That is amazing, because you’re right, I mean, in something that seems so simple and so inexpensive oftentimes gets dismissed, because we think that it’s not going to do enough, but some of these things that biochemically are happening to people Really need to start being addressed, because the side effects that they’re having with multiple layers of medications is not good for them either. James greenblatt md 17:52Yeah, the amount of medications now, because of our kind of ineffective model, is just exploding, so people are taking 3, 4, 5 psychiatric medications to treat a problem that sometimes there might be a simpler solution. Dr. Deb Muth 18:11Yeah. Can you share a case example of where an integrative approach really transforms someone’s mental health when medication alone wasn’t working? James greenblatt md 18:22Sure, you know, many, but there’s one that I just talked about, A couple nights ago about a gentleman who, you know, traveled around the country seeing integrative doctors, as well as traditional doctors, had a bag full of supplements, because every Doctor put them on a different regimen. And, strong family history of depression and addiction. He struggled with depression and addiction. And, you know, could not get off antidepressants. So, he had a lot of blood work, everything was normal, and the one test that we found in our battery was low levels of essential amino acids. Dr. Deb Muth 19:08Wow. James greenblatt md 19:09So this was, someone who was eating, you know, organic foods and grass-fed protein, so he was eating the perfect diet.But he was completely deficient in amino acids. So, again, that inability to digest and absorb, so just by giving this individual hydrochloric acid. Free-form amino acids. He was able to begin to feel better, and eventually we were able to taper him off these medications. So it was just, it wasn’t dietary intake, it was a problem of digestion and absorption. Dr. Deb Muth 19:50That is incredible, because I don’t think, even in the functional medicine world, where we’re focused so heavily on gut health, we are not making that correlation that people are not digesting their proteins to make amino acids, to make neurotransmitters. That… that thought process isn’t happening with a lot of functional medicine practitioners either. James greenblatt md 20:11No, it hasn’t, and maybe because it’s too simple, you know? It’s not trying to look at 75 markers on organic acid, it’s just… Dr. Deb Muth 20:21Yeah. James greenblatt md 20:21Looking at, you know, 9 essential amino acids. And usually there’s a pattern. They’re either all low, you know, or normal, or high, and that means something. So, I remember when I first did amino acid testing, it was by mistake. I remember in the 90s, I checked the wrong box in a lab company. And it didn’t make sense to me when I first started doing it, but now it is one of the most important tests that I do for adult depression. Dr. Deb Muth 20:49Yeah. How do those amino acids, work with, like, that resistant depression, anxiety. What do they actually do that makes the anxiety and the depression worse? James greenblatt md 21:02Well, the essential amino acids, essential meaning our body needs to get them from our diet, are the precursors to every protein in the body, but in psychiatry, they’re the precursors to the neurotransmitters.So, tryptophan, precursor to serotonin, phenylalanine, the precursor to dopamine and norepinephrine. So if those are deficient.And we have studies in humans and animals, going back, I think, to the 70s, that we can affect the levels of neurotransmitters in the brain. So low levels of these amino acids affect neurotransmitters. It’s actually a research protocol called tryptophan depletion studies. Where we give people in the lab low levels of tryptophan, and we watch them get irritable, depressed, and angry. Dr. Deb Muth 21:51It’s interesting that we’re willing to do that to people, right? But you’ve got to figure it out sometimes. You have to know that what you think is actually working. James greenblatt md 21:58Absolutely. Dr. Deb Muth 22:00Yeah. How do you guide patients to safely combine their natural approaches with their psychiatric medications? James greenblatt md 22:09I think the vast majority of the, the work that we’ve been doing, is all nutritional supplements or interventions that can be done with medications. So it’s not an either-or model when we think of functional psychiatry. It’s just kind of adding tools you know, to the toolbox. There are very few interactions with medications. Sometimes high-dose amino acids we won’t use with certain medications, but all the Vitamins and minerals and gut support that we’re recommending can be utilized with medications. Dr. Deb Muth 22:49That’s awesome, because I think there’s a lot of fear around that, right? Like, if I take this, it’ll interfere with that. And some things, yes, they do interfere, but it’s good for people to understand that they can do these things safely, but they need to work with somebody knowledgeable, like yourself, or somebody that has come from one of your training programs that really, truly understands this. James greenblatt md 23:10Yeah, absolutely. It’s, it’s an integrative model where individuals can Sometimes it’s just the medications work better. Other times, it’s a path to tapering someone off the medications. Dr. Deb Muth 23:24Yeah. For patients or families that are listening, and they’re really feeling frustrated by medication-only solutions, where do you recommend that they start? James greenblatt md 23:36Well, I have to say my book. So, you know, the book I just wrote, Finally, Hopeful, is written for patients, and I think the title is the best part of it, you know, Hope. I think as you begin to appreciate the role of nutrition and depression. So, there are some, some good books out there, that, on my website, psychiatryRedefine.org, there’s a list of clinicians, and, in the next month, I’ll be setting up a network of functional psychiatry clinicians, So, around the country that have been trained, so that program is called Finally Living Now, I think, Finally Living Now, so…People, want the information. Too many of our traditional docs just don’t have the training, so we’ll hopefully be able to provide a network of clinicians who can help. Dr. Deb Muth 24:30That’s fantastic, and for those of you who are driving or didn’t catch those links, don’t worry about it. We will have them in the show notes for you, so you can find these people that have been trained and understand what to do to help you. What gives you optimism about the future of psychiatric and mental health care? James greenblatt md 24:51Well, the explosion of research is really, have given me some renewed energy at this point in my career, because in the last 5 years. There are just hundreds of incredibly well-written academic articles, references that our traditional researchers have kind of just validated everything that we’ve been saying for 30 years. So we have studies on vitamin D deficiency, and suicide, and zinc deficiency, and suicide, and folate, and the gut. And the most significant for me is, I’ve been talking about lithium orotate. Dr. Deb Muth 25:34Print this. James greenblatt md 25:34years as a nutritional intervention, probably the most important in my practice, and a study came out of Harvard. This year, Describing lithium orotate, the only lithium preparation that was able to reverse Alzheimer’s pathology in mice models. and prevent it in these models. It was a pretty dramatic study. Dr. Deb Muth 25:57Oh. James greenblatt md 25:58So… Long-inded answer, but it’s the research now that is just supporting everything we’ve been yelling about for 30 years that just is going to make it much easier to train doctors and nurse practitioners so we can help more patients. Dr. Deb Muth 26:15Oh, that’s fantastic. That’s an… I’m going to look up that study, that’s amazing. So, one last question for you is, if someone was listening today, and they’re really struggling with anxiety and depression, and they’re out of answers, what would you tell them to give them hope? James greenblatt md 26:32I think that, you know, I’ve been doing this 30 years, and I have colleagues around the globe, and Everyone would kind of just echo that there are some simple interventions, and to try to find either your primary care doctor, or a mental health professional, or a naturopath who will dig deeper and look at some objective tests, and I’m positive that if you’re struggling with depression, that they’ll find something to help you. Dr. Deb Muth 27:06That’s awesome. Thank you so much for joining us today. Are there any last thoughts that you want to leave with our listeners? James greenblatt md 27:13Well, just to repeat two things I’ve said a couple times is, hope, you know, finally hopeful is the book, and then everyone’s different. And your neighbor might be taking, you know, found out that they had a vitamin B12 deficiency, and that cured their depression. it doesn’t mean you have a B12 deficiency, but there are many. a path towards looking deeper. Everyone’s different, but there is hope. Dr. Deb Muth 27:44Thank you so much for joining me today. James greenblatt md 27:46Thanks for having me, nice talking with you. Dr. Deb Muth 27:52Thank you for joining me today on Let’s Talk Wellness Now and Dr. James Greenblatt for the insightful conversation on integrative psychiatry and the future of mental health.If you’ve ever felt dismissed, over-medicated, or frustrated by cookie-cutter approaches to mental health, remember, there is always hope. Healing begins when we look deeper at nutrition, environment, biochemistry, and the unique story within every patient. That’s the art and the science Dr. Greenblatt calls us back to. If today’s episode resonated with you.Share it with someone who needs to hear that mental health illness is not a life sentence. It’s a message from the body, asking to be completely understood. Remember, wellness isn’t just about feeling good, it’s about thriving in every area of your life. If you’re ready to explore how root cause psychiatry or functional medicine can help you or a loved one find hope again, visit DrGreenblatt.com and check out his new book that is just out. Until next time, I’m Dr. Deb, reminding you to take care of your body, mind, and spirit. Be well, and I will see you in our next episode.The post Episode 263 – Functional and integrative psychiatry: combining nutrition, biochemistry, and lifestyle with mental health care first appeared on Let's Talk Wellness Now.

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ReferencesInt J Biochem Cell Biol. 2008 Nov17;41(6):1241–1244. J Clin Med. 2023 Feb 2;12(3):1199Guerra, DJ. 2026. Unpublished LecturesJ Clin Invest. 2025;135(2):e185218Kath, T. 1972. Alma Mater. Chicago.https://open.spotify.com/track/658elGePmaXtBTgPwDFi1S?si=c3266444c2384558Mozart, WA. 1791. Requiem Mass in D Minor (Unfinished) K.626https://music.youtube.com/playlist?list=OLAK5uy_nSNY0VtEjG1DYcoE6gg9tibETknwAWeLY&si=3HwngX5QTcFhRWGL

It's no secret that students' interest in STEM keeps growing. With an overwhelming number of different fields to pursue and growing opportunities for high schoolers, where do they start? Summer Science Program International (SSPI) helps students develop a deeper love for STEM and research through SSPI's immersive, rigorous, and collaborative summer program. SSP is a highly competitive (10,000 applicants for about 700 spots this year) 60-year old STEM program (Summer Science Program) that empowers students to follow their passions and more importantly gives them the opportunity to participate in rote experiments and gain hands-on experience, vs. being taught about STEM.  Key program study topics include astrophysics, bacterial genomics, biochemistry and cell biology.These flagship summer programs are a rigorous five-week residential summer research experience designed for highly motivated high school juniors. Participants engage in advanced research in astrophysics, biochemistry, bacterial genomics, and synthetic chemistry while living on a college campus. Summer Science Program has offered participants “the educational experience of a lifetime” for over 66 years, and program alumni have gone on to leading positions in industry, business, innovation, and more.Amy Hee Kim joined SSP International in 2025 as the Chief Program Officer, bringing 15 years in STEM fields as well as her background as a physical chemist (PhD from University of Chicago). Before joining SSPI, Amy served as the Executive Director of EnCorps helping STEM professionals become teachers in under-resourced community schools.Connect with Amy & SSP International:Website: ssp.orgYouTube: @sspinternational Instagram: @summerscienceFacebook: @SummerScienceProgramAmy's email: amy.kim@ssp.org Amy's LinkedIn: linkedin.com/in/amy-hee-kim-b6507b7/Chris Woods is the host of the STEM Everyday Podcast... Connect with him:Website: dailystem.comTwitter/X: @dailystemInstagram: @dailystemYouTube: @dailystemGet Chris's book Daily STEM on AmazonSupport the show

ReferencesGuerra, DJ. 2026. Unpublished Lectures.Fogerty, John 1970. Run Through the Jungle. CCRhttps://open.spotify.com/track/6J0AjzrYsPZrQtw6IjErhy?si=70f7f297e2ef4397Jaeger/Richards. 1966. Paint it Black. Roling Stoneshttps://open.spotify.com/track/63T7DJ1AFDD6Bn8VzG6JE8?si=c820099339724a3bCetera/Seraphine 1971. Lowdown. Chicagohttps://open.spotify.com/track/5h24XVIsohtANfjhkL8fKB?si=ab6fa245e3e84e17

ReferencesGenes Immun. 2020 May;21(3): 150–168.Cell Reports 2019, 29, Oct 932–945Transl Psychiatry. 2019; 9: 272Nat Commun. 2020; 11: 4664.Circulation. 2020 Oct 23;142(24):2338–2355Guerra, DJ.2026. Unpublished LecturesSchubert, F. 1826. String Quartet 14 in D Minorhttps://music.youtube.com/watch?v=CSdlrvC08lM&si=w222HNFTOEVmSmW2Lamm, R 1969. Beginnings. CTAhttps://open.spotify.com/track/5cn5xzaVKSheUb4DvTwMBT?si=5174a0df953b48e2

Most lawyers treat networking like a necessary evil, but what if you approached it as a science of human relationships instead of sales? In this episode, you'll learn how to build a small, powerful circle of trusted relationships that drive referrals, opportunities, and long-term career security.   In this episode, Steve Fretzin and Dillon Zwick discuss: The Harvard study on adult development and why relationships drive happiness How to reframe networking from “selling” to genuine relationship building Finding common ground and “natural affinities” to build trust Prioritizing and qualifying strategic partners using likability and referability Using systems, Dunbar's numbers, and cadence to maintain a high-value network   Key Takeaways: Long-term health, happiness, and even business success are far more correlated with the quality of your relationships than with money, status, or genetics. Networking works best when it is treated as a relationship-building exercise rooted in curiosity and service, not as a pitch or sales event. Common ground, including shared background, interests, values, or experiences, is one of the fastest and most reliable ways to create authentic connection and trust. Because time is limited, you need to intentionally prioritize relationships based on both how much you genuinely like someone and how capable and inclined they are to create opportunities for others. A simple, consistent follow-up system and a realistic understanding of how many relationships you can truly maintain, based on Dunbar's research, can ensure you are never forgotten and rarely without work.   "Relationships don't happen just by happenstance. You have to invest in your relationships and the people around you to develop them." —  Dillon Zwick   Check out my new show, Be That Lawyer Coaches Corner, and get the strategies I use with my clients to win more business and love your career again.   Ready to go from good to GOAT in your legal marketing game? Don't miss PIMCON—where the brightest minds in professional services gather to share what really works. Lock in your spot now: https://www.pimcon.org/   Thank you to our Sponsor! Rankings.io: https://rankings.io/ Lawyer.com: https://www.lawyer.com/   Ready to grow your law practice without selling or chasing? Book your free 30-minute strategy session now—let's make this your breakout year: https://fretzin.com/   About Dillon Zwick: Dillon has spent about 5 years in the field of corporate renewal with a background in heavy industrial design and manufacturing. Dillon's primary team role has been finding opportunities, solving difficult problems, and figuring out whatever needs to get done. He has helped numerous client companies successfully work through the corporate restructuring process. In that capacity, he has worked closely with CEOs, CFOs, and their respective accounting staff to support cash-constrained situations, providing transparency and strategic analytical support to the restructuring process. Dillon earned a B.S. in Biochemistry and a B.A. in History from the University of North Texas in 2011. He serves as President on the Turnaround Management Association – Central Texas chapter board, along with being a Director of the Association of Corporate Growth NextGen – Austin/San Antonio chapter board.   Connect with Dillon Zwick: Website: https://meadowlarkadvisors.com/about/bio-dillon/ LinkedIn: https://www.linkedin.com/in/dillon-zwick/   Connect with Steve Fretzin: LinkedIn: Steve Fretzin Twitter: @stevefretzin Instagram: @fretzinsteve Facebook: Fretzin, Inc. Website: Fretzin.com Email: Steve@Fretzin.com Book: Legal Business Development Isn't Rocket Science and more! YouTube: Steve Fretzin Call Steve directly at 847-602-6911   Audio production by Turnkey Podcast Productions. You're the expert. Your podcast will prove it. 

Dr. Tara Sander Lee is a Founding Board Member of SALT, Science Alliance for Life and Technology. She is a Science Advisor and Consultant who earned her Ph.D. in Biochemistry from the Medical College of Wisconsin. She has over 30 years' experience in public policy, academic research and clinical medicine with an emphasis on the cause of pediatric disease There are numerous debates as to how far we can delve into scientific research and still hold to a system of ethics. Some say it really doesn't matter as long as it's for the common good. Take, for instance, embryonic stem cell research. Some will claim that since aborted baby tissue would otherwise go in the trash, it's fine to use it for experimentation. Others contend the use of fetal body parts from aborted babies in vaccines and treatment are also okay if others are being helped by it. Did you know there are labs that create human embryos solely for experiments? These embryos are usually destroyed once research is complete. Also, did you know aborted fetal tissue is still used in some medical studies? This research often happens without public awareness or consent. And what about the use of AI? AI tools are shaping choices in healthcare, pregnancy and research. If left unchecked, this can target those who are disabled, the unborn or even older adults. We are headed down a pathway of very concerning technologies, genetic screening, gene editing, cloning, artificial wombs, 3-parent embryos and even human-animal chimeras. Where do we draw the line? When is it time to put the brakes on scientific research to protect ethics and prevent us from going down the pathway of eugenics?

Guest: Captain David Hoy (Edmonton Fire Rescue Services)How we handle the first 24 to 72 hours after a critical incident determines whether a call becomes a "memory" or a "trauma." In this episode, Nole and Kevin sit down with David Hoy, a 20-year fire captain and peer support specialist from the "Great White North" of Edmonton, Alberta.Dave breaks down the "Gold Standard" of reintegration, a program that has led to a 75% reduction in long-term mental health claims, and shares the five physiological pillars every first responder needs to regulate their nervous system after a bad shift.In This Episode, We Discuss:The Reintegration Whiteboard: How Edmonton's "Gold Standard" program uses a specific debriefing process to identify "hotspots" before they become injuries.The Bio-Chemistry of Trauma: Why stimulants (caffeine/nicotine) and depressants (alcohol) during the 72-hour "encoding window" can permanently scar the brain's storage of an event.The Trauma Backpack: A powerful analogy for identifying which burdens are yours to carry and which boulders need to be left at the station."Dig Your Well Before You're Thirsty": Practical advice on interviewing clinicians while you're healthy to ensure you have a "tactical" baseline for when things go south.Functional Disconnection vs. Reconnection: The biological necessity of shutting down emotions on a call, and the specific relational tools needed to turn them back on when you walk through your front door.Sub-Zero Firefighting: What it's like to fight fire at -30 and how to prevent getting literally frozen to your equipment.The 5 Pillars of Post-Call Regulation:If you've had a "bad night," Dave recommends hitting these five marks within 72 hours to restore homeostasis:Hydration: Flushing the "lactic acid of trauma" out of your system.Nutrition: Avoiding the "sugar-crash" cycle.Exercise: Utilizing cardiovascular work to process adrenaline.Sleep: The essential phase for brain restoration and memory filing.Physical Connection: Utilizing the release of oxytocin through intimacy to reset the nervous system.Big thank you to My Epic and Facedown Records for the use of their song "Hail" in our podcast!https://www.youtube.com/watch?v=Dz2RZThURTU&ab_channel=FacedownRecordsGet signed up for the next trip with Hold the Line!https://www.fireupprogram.org/hold-the-lineThe Fire You Carry on YouTube.Sign up for a class at The Fire Up Program!https://www.fireupprogram.com/programsThe Fire Up Progam video.https://www.youtube.com/watch?v=I__ErPW46Ec&t=12s&ab_channel=FireUpProgramThe Fire You Carry Instagram.https://www.instagram.com/thefireyoucarry/Donate to The Fire Up Program.https://www.fireupprogram.com/donateThe Fire Up Program Instagram.https://www.instagram.com/fireup_program/Kevin's Instagram.https://www.instagram.com/kevinpwelsh/?hl=en