Podcasts about Biochemistry

mRNA vaccines are not supposed to contain DNA. But Dr. Jessica Rose says a new study tested “32 vials of Pfizer and Moderna COVID products that included 16 unique lots… We did not only find DNA, we found it in ALL lots tested and most importantly, the DNA levels were all above pre-designated EMA thresholds of 10 ng/dose.” “We measured the amount of DNA in the vials using 2 methods… (qPCR and fluorometry),” she continues. “It was submitted as evidence on the congressional record by the honorable Senator Ron Johnson.” JP Sears is a comedian, author, and YouTuber known for his satirical take on politics, fitness, and faith. He hosts Awaken with JP on Rumble and YouTube. Follow at https://x.com/AwakenWithJP Dr. Jessica Rose is a Canadian researcher with a Bachelor's in Applied Mathematics and a Master's in Immunology from Memorial University of Newfoundland. She holds a PhD in Computational Biology from Bar Ilan University and completed postdoctoral research in Molecular Biology and Biochemistry. Find her at https://jessicasuniverse.com and follow at https://x.com/JesslovesMJK 「 SUPPORT OUR SPONSORS 」 Find out more about the brands that make this show possible and get special discounts on Dr. Drew's favorite products at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/sponsors⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠• FATTY15 – The future of essential fatty acids is here! Strengthen your cells against age-related breakdown with Fatty15. Get 15% off a 90-day Starter Kit Subscription at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/fatty15⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • PALEOVALLEY - "Paleovalley has a wide variety of extraordinary products that are both healthful and delicious,” says Dr. Drew. "I am a huge fan of this brand and know you'll love it too!” Get 15% off your first order at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/paleovalley⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • VSHREDMD – Formulated by Dr. Drew: The Science of Cellular Health + World-Class Training Programs, Premium Content, and 1-1 Training with Certified V Shred Coaches! More at https://drdrew.com/vshredmd • THE WELLNESS COMPANY - Counteract harmful spike proteins with TWC's Signature Series Spike Support Formula containing nattokinase and selenium. Learn more about TWC's supplements at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twc.health/drew⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 「 MEDICAL NOTE 」 Portions of this program may examine countervailing views on important medical issues. Always consult your physician before making any decisions about your health. 「 ABOUT THE SHOW 」 Ask Dr. Drew is produced by Kaleb Nation (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://kalebnation.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠) and Susan Pinsky (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/firstladyoflov⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠e⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠). This show is for entertainment and/or informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Kristen Lynch is a Professor and Chair of Biochemistry and Biophysics at the University of Pennsylvania. Kristen's research focuses on alternative splicing. Her lab is investigating how cells decide when to use an entire portion of the DNA instruction manual versus when to exclude parts of the instructions that are not useful or would be harmful. In particular, Kristen is interested in alternative splicing in the immune system and what happens when cells are faced with an immune challenge. When she's not at work, Kristen loves being outdoors. She spends her free time kayaking, paddle boarding, biking, hiking, and doing yoga. She received her B.A. in biochemistry and her Ph.D. in biochemistry from Harvard University. Afterwards, Kristen pursued postdoctoral training at the University of California, San Francisco. She served on the faculty at the University of Texas Southwestern Medical Center prior to joining the faculty at the University of Pennsylvania in 2009. Kristen is the recipient of many awards and honors for her work, including a National Science Foundation CAREER Award. She joined us for an interview to talk about her experiences in life and science.

ReferencesGuerra, DJ. 2025. Unpublished Lectures Trends Pharmacol Sci. 2009 Mar 9;30(4):174–181Molecular Neurobiology (2020) 57:5167–5176Stewart, S.. 1969 Everyday Peoplehttps://music.youtube.com/watch?v=YUUhDoCx8zc&si=HwMawlaaswvtMYHpLennon/McCartney. 1965. Girl. Beatles Rubber Soul.https://music.youtube.com/watch?v=-8l3ntDR_lI&si=AW3pAelz8CfJHGbyBetts, D. 1973. Ramblin Man. Allman Brothershttps://music.youtube.com/watch?v=A-bSe0i69yA&si=kVH2vGhBAKT2ENDR

Episode 062 | Bonnie Hodge, MD is a board certified dermatologist originally from Meridian, Mississippi. She specializes in skin cancer detection and treatment, management of psoriasis, acne, rosacea, atopic dermatitis, other common inflammatory conditions, and more complex conditions such as autoimmune and bullous dermatoses, pigmentation disorders, vitiligo, and prurigo nodularis.As a recent residency graduate, she has undergone extensive training in cutting-edge, evidence-based treatment strategies. She worked under several world-renowned experts in psoriasis, melanoma detection, alopecia, and pigmentary disorders.Dr. Hodge caught my eye through her rising, homegrown stardom on social media. As of the publication of this episode, she has amassed over 54K followers on TikTok! Her story is a great example of what can happen when you have the courage to leverage your expertise by consistently putting yourself in front of a camera and into the algorithm. Given the amount of misinformation our patients are routinely exposed to, the more board certified dermatologists who are willing to do this in an engaging, educational, and entertaining way, the better! Dr. Hodge graduated with a degree in Biochemistry from Mississippi State University. She received an MD from the University of Mississippi Medical Center School of Medicine and completed her dermatology residency at The University of Alabama, Birmingham.Outside the office, you'll find her enjoying life with her husband, Sonny, a sports medicine physician, and their son, Walker, alongside their canine companion named, Sipsey.This episode was recorded on May 27th, 2025.Connect with and learn from Dr. HodgeDr. Hodge on TikTokDr. Hodge on IGDr. Hodge at Haley DermatologyMore from Dr. Lewellis and Above & Beyond DermatologyNeed a dermatologist? Fill out this short interest form, text or call me at 715-391-9774, or email me at drlewellis@aboveandbeyondderm.com if you'd like to have a no obligation discovery call. I offer in-office visits, house calls, and virtual care in Wisconsin and virtual care in Illinois, Nebraska, and Colorado.Have an idea for a guest or want to be on the show yourself? Send me a text or email, and we'll see if it's a good fit.Above & Beyond DermatologyNutrafol -- special pricing and physician exclusive productsNeoGenesis -- my favorite source of stem cell released molecules for skin/hairSilagen.biz -- physician dispensed scar refinement products delivered to your door (use practice code 1206240832P)NewsletterLinkedInFacebookDr. Lewellis on InstagramAbove & Beyond Dermatology on InstagramYouTubeTikTokTwitter/XChange Your Mind, Change Your LifeSoMeDocs (Doctors on Social Media)Pippa!

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden and Dr. Nichola Conlon delve into the complexities of aging, focusing on the important role of NAD (Nicotinamide Adenine Dinucleotide) in cellular health and longevity. They discuss how NAD levels decline with age, the implications of this decline, and innovative strategies to boost NAD levels effectively. The conversation also touches on the limitations of IV NAD therapy, the importance of addressing inflammation, and the scientific validation behind the Nuchido Time product. Dr. Conlon shares insights into future research directions and the impact of customer feedback on product development, emphasizing the need for a comprehensive approach to enhancing cellular health.   For Audience ·       Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ !  ·       www.nuchido.com/GLADDEN or simply use code GL20 at Checkout on www.nuchido.com for 20% off your first order!   Takeaways ·       NAD is crucial for driving cellular repair processes. ·       The decline of NAD is linked to aging and inflammation. ·       Addressing root causes of NAD decline is essential. ·       IV NAD therapy may not effectively increase intracellular NAD levels. ·       NAD recycling is a complex process influenced by various enzymes. ·       Chronic inflammation can significantly deplete NAD supplies. ·       Nuchido Time aims to optimize NAD levels through a comprehensive approach. ·       Customer feedback drives ongoing research and product development. ·       NAD levels fluctuate throughout the day, impacting circadian rhythms. ·       Future studies will explore NAD's effects on sleep and skin quality.   Chapters 00:00 Introduction and Background 04:00 The Importance of NAD in Aging 07:45 Understanding NAD Depletion and Its Causes 12:47 The Role of CD38 in NAD Dynamics 16:42 Innovative Approaches to NAD Supplementation 21:26 Comparing NAD IVs and Oral Supplements 25:12 Enhancing NAD with Ozone Therapy 28:04 Product Development and Optimization 33:47 Future Research Directions and Applications   To learn more about Dr. Nichola Conlon: Website: www.nuchido.com Email: care@nuchido.com Social media: @nuchido @drnicholaconlon Got a question for Dr. Gladden? Submit it using the link below and it might be answered in our next Q&A episode! https://form.typeform.com/to/tIyzUai7? Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw    

ReferencesInt J Mol Sci. 2022 Jul 8;23(14):7592. Exp Mol Med . 2024 Apr;56(4):946-958.Front Endocrinol (Lausanne). 2020 Jul 29;11:483.Nature Structural & Molecular Biology 2025 .32, pages431–440 Kath, T. 1970.Memories of Love Chicago II https://music.youtube.com/watch?v=GFjWeUnt6nY&si=mHjfAhTlwVyXE0ZMSchubert, F. 1829. Standchen 4 D 957https://music.youtube.com/watch?v=pJf-XXTBEqs&si=2fMoDFFsHz_i1H0GSimon, P. 1966. Scarborough Fare.https://music.youtube.com/watch?v=-Jj4s9I-53g&si=OA7lBVGkiPXlPpoJLennon/McCartney. 1966. Rainhttps://music.youtube.com/watch?v=nrEgtOeJGzQ&si=D1lQwT-_ck2pBD_X

ReferencesInt J Mol Sci. 2022 Jul 8;23(14):7592. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology2012. Volume 163, Issue 1, September. Pages 26-36Molecular Neurobiology 2019. v.56, pages 5436–5455, Lennon/McCartney. 1970.. One After 909. From Let It Be lphttps://music.youtube.com/watch?v=t8UeWjynWvE&si=aUHXUFiv315uNWWkPetty/Lynne/Campbell. 1989. Running Down a Dreamhttps://music.youtube.com/watch?v=8MUg8mpnhvQ&si=HgcU5gWoA753gOmCBruce/Brown. .1968. Deserted Cities of the Heart. Live Cream II.https://music.youtube.com/watch?v=kBHh2d4zhV8&si=22Cdzk9XrRK_AUakDavies, R. 1979 Low Budgethttps://music.youtube.com/watch?v=FbCZJbPcJFI&si=EEjUj-QobN04yzOA

In this episode of The Birth Lounge Podcast, HeHe sits down with clinical pharmacist Dr. Michaela Wachal to unpack the controversy surrounding Tylenol (acetaminophen) use in pregnancy and its potential links to autism and other neurodevelopmental concerns. Together, they dive into what the research actually says (and doesn't say), why transparency and informed consent are so important, and how to navigate decisions around medications in pregnancy with confidence. Dr. Wachal also highlights the bigger picture, like how genetics, environmental toxins, and even maternal stress can play a role in outcomes, and why caring for yourself is just as critical as any prescription. This conversation is packed with nuance, evidence, and practical takeaways to help you feel informed, empowered, and ready to advocate for yourself as you make decisions about your pregnancy care. 00:00 Introduction and Media Misrepresentation 01:05 Personal Story and Birth Lounge App 02:16 Empowering Prenatal Conversations 05:26 Emergency Use Authorization Episode 07:34 Interview with Dr. Michaela Wachal 09:14 Medication Safety in Pregnancy 12:37 Pharmaceutical Industry Failures 15:20 Personal Journey and Advocacy 18:55 Questioning Medical Norms 21:15 Tylenol and Toxins 23:34 Aluminum in Vaccines 27:32 The Importance of Transparency 37:05 Advocating for Education and Understanding 37:51 The Power of Asking Questions 40:21 Nesting and Preparing for Baby 43:17 Managing Fevers During Pregnancy 52:01 Environmental Toxins and Health 01:00:41 Therapies and Support for Children on the Spectrum 01:09:27 Final Thoughts and Encouragement   Guest Bio: Michaela Wachal, PharmD, CSP, is a clinical pharmacist, Certified Specialty Pharmacist, and Clinical Accreditation Manager with nearly a decade of experience in specialty pharmacy. She holds a Doctor of Pharmacy degree from the University of Nebraska Medical Center and a Bachelor of Science in Biochemistry from Doane University. Throughout her career, she's specialized in complex conditions including oncology, fertility, endocrinology, immunology, mental health, and inflammatory diseases—always with a passion for improving patient care, optimizing healthcare systems, and empowering women in medicine. Michaela is also a mom of three, including one child with autism, ADHD, and anxiety, which ignited her deep interest in neurodiversity, integrative health, and individualized medicine. After navigating her own family's challenges, she began researching functional and evidence-based approaches to support children and families living with complex needs. Online, Michaela shares insights from scientific studies on autism, ADHD, vaccines, autoimmune conditions, toxins, and more, always with a focus on helping parents make informed, evidence-based choices. Her work blends professional expertise with personal passion, making her a trusted voice in both the pharmacy world and the parenting community.   INSTAGRAM: Connect with HeHe on IG  Connect with Dr. Wachal on IG    BIRTH EDUCATION: Join The Birth Lounge here for judgment-free childbirth education that prepares you for an informed birth and how to confidently navigate hospital policy to have a trauma-free labor experience!   Download The Birth Lounge App for birth & postpartum prep delivered straight to your phone!   RESEARCH MENTIONED: 2021 there's a call for action published supported by 91 scientists, clinicians and public health professionals across the globe recommended that pregnant women should be cautioned at the beginning of pregnancy to forego APAP unless it is medically indicated and to minimize the exposure by using the lowest effective dose for shortest possible time https://pubmed.ncbi.nlm.nih.gov/34556849/   Boston Birth cohort published in 2020 looked at acetaminophen metabolites in cord blood samples collected at birth and unchanged acetaminophen levels were detected in all cord plasma samples and acetaminophen burden was associated with higher odds of ADHD  and ASD daignosis there was a 2.3 to 3.5 increased risk for ADHD and 1.6 to 4.1 increased risk for ASD https://pubmed.ncbi.nlm.nih.gov/31664451/   Recently in August Harvard did an analysis using the Navigation Guide methodology that supports evidence consistent with an association between acetaminophen exposure during pregnancy and increased incidence of Neurodevelopmental disorders. This included 46 studies with 27 reporting positive associations with the higher quality studies more likely to show positive correlations https://ehjournal.biomedcentral.com/articles/10.1186/s12940-025-01208-0   Nurses Health Study https://pubmed.ncbi.nlm.nih.gov/30923825/ Spanish birth cohort where acetaminophen exposure was associated with more hyperactivity/impulsivity https://pubmed.ncbi.nlm.nih.gov/27353198/   In 2018 there was a review that showed that 9 prospective cohort studies that all suggested an association between prenatal APAP exposure and neurodevelopmental outcomes - ADHD, ASD or lower IQ and longer duration was associated with increased risk https://pubmed.ncbi.nlm.nih.gov/29341895/   2022 a prospective cohort study in Pennsylvania looked at 2,423 moms using data and children who were exposed to APAP during pregnancy scored higher for child behaviors, sleep problems and attention problems  https://pubmed.ncbi.nlm.nih.gov/36170224/ Keywords: Tylenol pregnancy, acetaminophen pregnancy, Tylenol autism risk, pregnancy medication safety, prenatal care, evidence-based pregnancy, maternal health, neurodevelopment, pregnancy decision making, informed consent pregnancy, pregnancy medications, Dr. Michaela Wachal, Birth Lounge podcast, pregnancy self-care, pregnancy toxins

Dr. Nicole Paulk is the CEO, Founder, and President of Siren Biotechnology and has dedicated her career to advancing the field of gene therapy. With nearly two decades of expertise, Nicole has been at the forefront of developing cutting-edge advances to propel the field of gene therapy forward for a wide range of diseases. Nicole has held various leadership positions in academia and industry and most notably was an Assistant Professor of AAV Gene Therapy in the UCSF Department of Biochemistry & Biophysics before leaving to found Siren. Nicole has a B.S. in Medical Microbiology, a Ph.D. in Viral Gene Therapy and Regenerative Medicine from OHSU and completed her Postdoctoral Fellowship and Instructorship in Human Gene Therapy at Stanford University prior to starting her lab at UCSF. Nicole is a pioneer in the development of next-generation AAV platforms for gene repair, gene transfer and gene editing, directed evolution for novel engineered capsid evolution, and comparative multi-omic approaches to interrogate translational AAV biology.

ReferencesExp Mol Med. 2024 Apr 1;56(4):946–958.UBMB Life. 2010 May;62(5):347–356.Guerra, DJ. 2025. Unpublished LecturesCell Mol Immunol 2006 Feb;3(1):11-9J Neuroinflammation. 2019 Feb 25;16:48.Jones, S. 1948 . Ghost Riders in the Sky Johnny Cashhttps://music.youtube.com/watch?v=rRowehhX9I4&si=jco59v9Hi_BGWdy4Strauss, R. 1915. An Alpine Symphony OP.64https://music.youtube.com/watch?v=O8-M0ULcAy8&si=tXwy1CPpkQtYXose

This episode covers:In this episode, we discuss how trauma is stored in the body, the difference between stress and trauma, and practical somatic tools to start healing, and so much more.Dr. Aimie Apigian, MD, MS, MPH, is a double Board-Certified Physician, boarded in both Preventive and Addiction Medicine with a Masters in Biochemistry and a Masters in Public Health. She is a leader, speaker and founder of Trauma Healing Accelerated, LLC where she not only continues to lead individuals in their own healing journey but trains professionals around the world to do the same.After a few years in a general surgery residency in Portland, OR, Dr. Aimie decided to forge her career path as a Trauma, Attachment and Addiction Medicine Physician.  She believes the healing journey can be accelerated by bringing in the biology piece to trauma and applying strategic tools to address the chronic effects of trauma in one's body.  Having both parented children with effects from attachment and trauma issues and then having her own health challenges from chronic stress and traumas, she is intensely invested on finding what actually works practically and how to restore the body to its highest potential for health optimizing the biology.Links mentioned during this episode:Dr. Aimie's Book, The Biology of Trauma: https://book.biologyoftrauma.com/landing-pageFree Initial Consultation with Dr. Megan: https://p.bttr.to/3a9lfYkLyons' Share Instagram: www.instagram.com/thelyonsshareJoin Megan's Newsletter: www.thelyonsshare.org/newsletter

Send us a textHow nutrition and medications impact mitochondrial health.Wide release date: October 1, 2025.Episode Summary: Dr. Chris Masterjohn talks about the intricate relationships between nutrition, prescription drugs, and mitochondrial health, discussing how molecules like acetaminophen and SSRIs affect the body beyond their intended purposes, particularly impacting inflammation and energy metabolism. The discussion gets into the broader implications of serotonin outside the brain, the side effects of commonly used medications, and the importance of personalized nutritional strategies to optimize mitochondrial function.About the guest: Chris Masterjohn, PhD holds a doctorate in nutritional sciences and is a co-founder of Mitome, a company focused on mitochondrial testing to optimize cellular energy production.Discussion Points:Acetaminophen & Inflammation: Acetaminophen (Tylenol) may contribute to chronic low-grade inflammation by blocking both the initiation and resolution of inflammation, potentially linked to health issues like autism when used during pregnancy.Serotonin's Role Beyond the Brain: Approximately 95% of serotonin is found in the gut, regulating motility, with SSRIs causing side effects like nausea due to increased extracellular serotonin.SSRIs & Mitochondrial Function: SSRIs disrupt serotonin uptake into cells, reducing mitochondrial melatonin production, which impairs the body's ability to handle hypoxic stress and produce ATP efficiently.Statins & Mitochondrial Impact: Statins, used to lower cholesterol, inhibit the mevalonate pathway, affecting not just cholesterol but also CoQ10 and vitamin K2, crucial for mitochondrial function, potentially leading to side effects like myopathy.Mitochondrial Testing with Mitome: Masterjohn's company, Mitome, uses cheek swab tests to measure mitochondrial respiratory chain activity, providing personalized dietary and lifestyle recommendations to optimize cellular energy production.Nutrition & Mental Health: Masterjohn shares his personal experience of severe mental health issues on a vegan diet, which improved dramatically with a nutrient-dense diet rich in organ meats, highlighting individual nutritional needs.Energy Metabolism's Universal Role: Mitochondrial ATP production governs everything from daily energy levels to long-term health, with personalized testing helping identify and address specific bottlenecks.*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Synopsis: When biotech meets bold partnerships, new models of innovation emerge. In this episode of the Biotech 2050 Podcast, host Rahul Chaturvedi welcomes Paul Biondi, Managing Partner at Flagship Pioneering, and Uli Stilz, Vice President, R&D External Innovation Partners at Novo Nordisk, to explore the power of co-creation. Together, they unpack how Flagship's pioneering medicines model and Novo's Bio Innovation Hub intersect to accelerate breakthroughs in obesity, diabetes, and cardiometabolic diseases. They share lessons on building trust, navigating crises, and structuring alliances that go beyond transactions into enduring innovation ecosystems. From human disease atlases to new frameworks for agile collaboration, this episode offers a rare behind-the-scenes look at how pharma and biotech can partner differently—turning complexity into transformative therapies. Biography: Paul Biondi is a Managing Partner at Flagship Pioneering, leading Flagship's product and partnering capabilities, including Pioneering Medicines, Partnering, and Pipeline and Product Innovation. In this role, Paul oversees Pioneering Medicines, Flagship's in-house drug discovery and development unit, as well as therapeutic partnering and business development efforts for the Flagship ecosystem, including driving broad institution-wide Innovation Supply Chain partnerships with biopharma companies to jointly conceive and create innovative products. Paul also works with Flagship company CEOs and their teams to achieve the best attainable value for each company, guiding them in their pipeline strategy, product concepts, R&D execution, and partnering approach. He serves on the boards of Flagship-founded companies, including Tessera Technologies (NASDAQ: TSRA) and Valo Health. Paul Biondi is Managing Partner at Flagship Pioneering, joining after 17 years at Bristol-Myers Squibb (BMS), where he served as SVP of Strategy & Business Development and held leadership roles in R&D. He previously spent nine years at Mercer Management Consulting. Paul earned his MBA from the Kellogg School of Management at Northwestern University and his B.A. from Dartmouth College. Uli Stilz is Corporate Vice President, R&D External Innovation Partners, External & Exploratory Innovation (E2I) at Novo Nordisk., based in Boston. He leads a global R&D team that builds creative partnerships with biotech, venture capital, academia, and research hospitals to co-create next-generation therapeutics in cardiometabolic and rare diseases. Building on the success of the Novo Nordisk Bio Innovation Hub, Uli and the E2I team drive an externally anchored portfolio of collaborations that stimulate global innovation ecosystems and advance Novo Nordisk's pipeline. Uli Stilz earned his Master's in Organic Chemistry from ETH Zürich and a Ph.D. in Biochemistry from the Max-Planck-Institute of Biochemistry in Martinsried, followed by postdoctoral research at Caltech. He began his industry career at Hoechst AG and later Sanofi, where he became Associate VP of the Innovation Unit in the Diabetes Division. Over two decades, he contributed to more than 60 preclinical and clinical drug candidates in cardiometabolic, immunology, and oncology. From 2012–2014, he served as President of the European Federation for Medicinal Chemistry. In 2014, Uli joined Novo Nordisk in Copenhagen and in 2019 moved to Boston to establish and lead the Bio Innovation Hub, now the External & Exploratory Innovation (E2I) organization. He also serves as Adjunct Professor at the University of Frankfurt, sits on editorial and scientific advisory boards, and holds board roles at the Kendall Square Association and Gensaic, while advising the aMoon Fund.

referencesExp Mol Med. 2024 Apr 1;56(4):946–958 J Cell Physiol.. 2024 May;239(5):e31230Guerra, DJ. 2025.Unpublished LecturesTownsend, P. 1971 Wont Get Fooled Again. From Who's Next The Whohttps://music.youtube.com/watch?v=Jtb10ZwbReY&si=jiRwoTM70ibkbAHdTownsend, P .1969 Pinball Wizard from Tommy lp.https://music.youtube.com/watch?v=3xZzGtDW2p4&si=7EROWKQO7DreWHHJAnderson, I. 1969. We Used to Know from Stand Up lp.Jethro Tull.https://music.youtube.com/watch?v=oGvux7w1Ea4&si=s8rzKSAvM4aQSahZMozart WA 1788. Symphony 41 in C Major K. 551https://music.youtube.com/watch?v=0VuSqLbFwXM&si=J4tvwnIBGUMbGlFL

ReferencesBiochem Pharmacol. 2021 Jan 28;185:114428.Signal Transduction and Targeted Therapy2021. 6. Article#402 Scientific Reports 2024. volume 14, Article number: 6651 Page/ Plant 1975.. Kashmir. Led Zepplin Physical Graffiti lphttps://music.youtube.com/watch?v=SsaFBNvhceA&si=Dc7cKj4BJeNAhaJVBiber,H. 1676. Violin Sonata 81 in A Major. C147.https://music.youtube.com/watch?v=ScciVuSXM2I&si=r3C5RVLzULbxv-fe

Jessica Sheldon (PhD) is on a mission to starve out Acinetobacter baumannii —one of the world's most virulent hospital-borne pathogens. Notorious for its speedy evolution and multi-drug resistance, the hospital-borne bacteria lingers on dry surfaces and infects critically-ill patients, leading to sepsis, pneumonia and high mortality rates. In this episode, Sheldon delves into the real-life events that drove her to investigate histamine, and its role in bacterial survival and immune response. In 2022, Sheldon joined the University of Saskatchewan's College of Medicine as an assistant professor of Biochemistry, Microbiology & Immunology -- something she now laughs about after an ill-fated high school placement in an immunology laboratory. “Cytokine cascades, pathways, the signaling just got way over my head real fast,” said Sheldon. “I didn't really know what I was doing.” Sheldon enrolled at Lakehead University, drawn to the tiny pathogens with outsized roles in movies like Outbreak. She estimates she read the book The Hot Zone 20 times. Her persistence paid off. “One of my second year microbiology teachers said, ‘you know, I think you're kind of good at this. Maybe you should try it as a career.' Sheldon zeroed in on metals and wrote her doctoral dissertation on the role iron plays in the proliferation of bacteria such as Methicillin-resistant staphylococcus aureus (MRSA). Today, she studies both Morganella morganii and Acinetobacter baumannii —  the multi-drug-resistant bacteria singled out twice in the last decade by the World Health Organization as a ‘priority 1-critical pathogen'. “I'm perpetually fascinated by the idea that something so small can change the course of history,” said Sheldon. “And we've seen that recently with COVID.” Sheldon was already studying the metal uptake and signalling systems that grow and sustain A. baumannii when the bacteria ripped through hospitals during the pandemic, attacking Covid-infected patients on ventilators. By 2023, Sheldon landed a five-year CIHR grant of $900,000 to study A. Baumannii and the way it turns histidine into histamine. Her goal is to pinpoint the way the pathogen uses histamine to evade its host, as it sends out siderophores to steal iron and other nutrients. The compound appears to serve as a signalling mechanism for both the host and the invading pathogen, she said. “We know the bacteria are using histamine in the synthesis of these molecules to get iron, but they're also secreting it into the environment. We're not really sure why,” Sheldon said. Her laboratory is working to trace and target those pathways, so researchers can identify and potentially develop new treatments — small molecules or antibody inhibitors that could disrupt multi-drug resistant pathogens. Beyond A. baumannii, histamine may hold the key to how some of the world's most notorious bacteria grow, spread, and evade immune defences, Sheldon said. “We're running out of drugs, but there's really not a full appreciation for the fact that we're losing the ability to treat bacterial infections,” Sheldon said.  “We need to develop supplementary therapies or alternative therapies.”

ReferencesCells. 2021 Jun 3;10(6):1382Mol Biol Rep. . 2023 Jan;50(1):777-788Open Access Library Journal .2017, Volume 4, e3492 J Interferon Cytokine Res. 2014 Aug 1;34(8):577–588International Immunopharmacology. 2020. Volume 80, March 06210Signal Transduction and Targeted Therapy 2021. 6, Article number: 402Lennon/McCartney. 1964. If I Fell .Hard Days Night lp. Beatleshttps://music.youtube.com/watch?v=F_80s6S_7Vw&si=6uePjPglrMjI_geCJoel, B. 1980. I Dont Want to Be Alone. Glass House, LPhttps://music.youtube.com/watch?v=vhn4mH3uA1A&si=dYT2W6BMDmMzmG1hTempchin, J. 1972. Peaceful Easy. Feeling. Eagleshttps://music.youtube.com/watch?v=QRMIgT3thFM&si=qSuX5m0F0r9K4UXwSchubert, F. 1827. Piano Trio in E flat. OP 100.https://music.youtube.com/watch?v=k_jknESj68E&si=_d19-CrGPKqOdJKo

ReferencesNature Reviews Drug Discovery.2022. 21: 339–358 Academia Biology, 2025.vol. 2, no. 3, J Cellular Physiol.2024.Volume 239, Issue 5 May e31230.Guerra, Dj. 2025. Unpublished LecturesSeeger, B. 1971. Turn the Page.https://music.youtube.com/watch?v=t9G6Ec1DDlc&si=8ixyA8ESHPXyUBAgSeeger, B. 1975. Katmandu.https://music.youtube.com/watch?v=4s1-e88R3OU&si=yGktYIc_HqM0QZFVMiller, S. 1972. Space Cowboyhttps://music.youtube.com/watch?v=95dM-K5fSKQ&si=EBMjIdvh5oPxjR2wMozart, WA> 1780. Violin Concerto 5. https://music.youtube.com/watch?v=vudKSLyeWEg&si=7SwEEUkSt4eOwAvo

As flu season rolls around, do you still need to get a Covid booster? Does the shingles vaccine have an impact on dementia? And how does disinformation fuel vaccine scepticism and herd immunity? Professor Cliona O'Farrelly, Chair in Comparative Immunology & Biochemistry at Trinity College Dublin answers these and other vaccine related questions.

Elizabeth Cronlund is joined by Marie Moy to confront some common narratives about Asian American and Pacific Islander populations. They take a look at some of the history of AAPI in the United States, and reflect on the ways that history informs where we find ourselves today. They also share some ways we can build coalitions and stand in solidarity so we are able to move forward together.Learn more about CCDA's AAPI Network at ccda.org/aapi. And make plans to join us at the CCDA Conference this November at ccda.org/conference.Marie Moy serves as the Director of Operations and is a member of the Restorative Practices training and implementation team at Erie County Restorative Justice Coalition (ECRJC). ECRJC's mission is to promote racial and social justice through Restorative Practices, providing training, coaching, consulting, and restorative responses, including Restorative Justice Conferencing in lieu of traditional punitive measures. Marie grew up in a small town in northern Indiana, where her parents owned a Chinese-American restaurant. As children, she and her sisters attended an independent Baptist church. Marie first learned of Christian Community Development while attending Renovation Church in Buffalo in 2010. She participated in CCDA's El Camino del Inmigrante in 2016 with approximately 70 others to bring attention to the plight of immigrants. Marie is a graduate of Northeastern Seminary at Roberts Wesleyan College in Rochester, NY, with an MA in Theology & Social Justice from Indiana University, Bloomington, with a BS in Biochemistry. Marie integrates her background in science and theology to bring just practices to the operations of organizations, and is particularly interested in creating spaces without traditional hierarchy that are inclusive and supportive of marginalized communities. As a second-generation Asian American, Marie is passionate about immigration reform in addition to her work with ECRJC to end mass incarceration and restore relationships and communities. Marie is married with two adult children and a small Cavalier King Charles/poodle mix named Chani. She is a member of the CCDA Board and Leadership Cohort 8, and the John R. Oishei Foundation Karen Lee Spalding Oishei Fellows for Leaders of Color. She is embarking on a sabbatical to spend time with God and an exploration of embodied restorative practices after a long season in nonprofit work.Based in Orlando, FL, Elizabeth Cronlund is the Partnership Development Manager with UNDIVDED, an organization that is activating communities for racial healing and justice. She has more than 15 years of experience in congregational ministry as a Christian Community Developer. Within CCDA, she helps lead the AAPI Network and is a contributing writer for CCDA's Education Equity Handbook. Elizabeth is a Certified Nonprofit Professional (CNP) and attends Northern Seminary.Connect with CCDA on Instagram, Twitter, Facebook, and LinkedIn. Follow CCDA on YouTube.

REFERENCES Autoimmun. 2012 Mar 28;38(4):344–353The Journal of Immunology, 2009. Volume 182, Issue Supplement_1, AprIL. Page 99.1, Trends in Immunology 2025. ReviewVolume 46, Issue 4p324-337AprilCytokine. 2024 Feb 15;176:156540. Proc Natl Acad Sci U S A. 2013 Jun 10;110(26):10652–10657J Cell Sci. 2019 Sep 16;132(18):jcs213124.Cellular & Molecular Immunology 2025. volume 22, pages134–149 Plant/Page.1971. Battle of Evermore on LZIV.https://music.youtube.com/watch?v=88b0OYxdtyM&si=axHZuES3K2lftqDTWinwood, S.1969. Had to Cry Today. Blind Faith.https://music.youtube.com/watch?v=Z4Yo_VbGdMg&si=Pq0OXwT0lW2pUmT8Mozart, WA. 1781. Idomeneo Overture K 366.https://music.youtube.com/watch?v=OAXn_rs17m4&si=nFI7jghahXFS7NhT

In this episode we discuss:   Whether Dr Ray Peat had it all wrong   Potential reasons why someone may be bloating from carbs How to add carbs back in following restrictive diet   Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/ Theresa's Instagram: https://www.instagram.com/livingrootswellness/   Timestamps: 0:00 – intro  0:32 – Justine Stenger's claim that Dr Ray Peat had it all wrong  6:15 – did Ray Peat ignore physics, structured water, and light?  11:41 – carbs vs fat: which fuel produces more ROS?  16:50 – Justine Stenger's claim that carbs act as a crutch for a damaged metabolism, and restoring redox is the solution  21:58 – carbs vs fat: which fuel produces more ATP?  25:27 – conflicting health information on social media and why the “Ray Peat diet” doesn't work  31:55 – common challenges with implementing Ray Peat's work  34:09 – Justine Stenger's mischaracterization of Ray Peat's work as a “dietary roadmap for people with a broken metabolism”  41:20 – why you shouldn't outsource critical thinking to social media influencers or AI  45:17 – Ray Peat's generosity with freely sharing advice and information  46:21 – improvements on a bioenergetic approach without extreme restriction  47:31 – why you may experience bloating from carbs and what to do about it  54:52 – what to do about gut dysbiosis and biofilms  56:56 – how to restore gut health and digestion when transitioning away from keto

ReferencesJ Neuroinflammation. 2019; 16: 236. Scientific Reports 2019. v.9, Article 1220 Thyroid. 2006 Dec;16(12):1221-7.JOURNAL OF BIOMOLECULAR STRUCTURE AND DYNAMICS. 2021, VOL. 39, NO. 7, 2526–254 Cell Mol Life Sci. 2022 Jul 12;79(8):419.J Autoimmun. 2012 Mar 28;38(4):344–353J Lipid Res. 2020 Feb 10;61(4):505–522 Lennon/MCartney. 1966. Eleanor Rigbyhttps://music.youtube.com/watch?v=wbxTlxuECJA&si=5VjMw91GnX6XRgaVJagger/Richards/Oldham. 1965. As Tears Go By.https://music.youtube.com/watch?v=_imgG-a_cNc&si=cSLN_tkuQ_1WBVorLake, G. 1970. Lucky Man. Emerson Lake and Palmerhttps://music.youtube.com/watch?v=Qs8F1a04rHY&si=6L0pIcbSoYyGX2F3McBroom, a. 1979. The Rose. Conway Twitty.https://music.youtube.com/watch?v=EWbS4Jg-rzY&si=pf1YNVnhwItZcskg

Sponsored by Denman X Hello Salon Prohttps://thetease.shop/products/hello-salon-pro-subscription-boxhttps://www.instagram.com/denmanpro/https://www.instagram.com/denmanbrush/Interview with Jared ReynoldsZenagen creator and founder, Jared Reynolds, first began searching for hair loss solutions as a medical student, when he noticed his hair thinning and shedding. Through his medical studies, Jared learned that high-quality nutraceutical ingredients and an advanced delivery system were key to creating a truly effective, natural and easy-to-use hair care product.Links:https://zenagen.com/ https://www.instagram.com/zenagenhair/ https://www.instagram.com/zenagenhairpro/ News from TheTease.com:https://www.thetease.com/mustafa-yanaz-brings-hair-hats-to-the-collina-strada-ss26-nyfw-show/https://www.thetease.com/how-mandee-tauber-created-those-epic-fishtail-braids-for-the-dauphinette-ss26-runway-show/More from TheTease.com:Instagram: https://www.instagram.com/readthetease/ (readthetease)Instagram: https://www.instagram.com/volumeupbythetease/ (volumeupbythetease)Instagram: https://www.instagram.com/kellyehlers/ / (KellyEhlers)Instagram: https://www.instagram.com/eljeffreycraig/ (eljeffreycraig)Web: https://www.thetease.com (TheTease.com)Email: VolumeUp@TheTease.comCredits: Volume Up is a Tease Media production. This episode was produced by Monica Hickey and Madeline Hickey. James Arbaje is our editor and audio engineer. Thank you to our creative team for putting together the graphics for this episode.Thank you to the team who helped create our theme song. Show them some love and check out their other work!Josh Landowski: https://www.instagram.com/josh_landowski/

ReferencesCell Mol Life Sci. 2022 Jul 12;79(8):419.J Autoimmun. 2012 Mar 28;38(4):344–353Trends in Immunology.2017. REVIEW| v. 38,I4, P287-297, Saint-Saens, C. 1886. Symphony 3 in C Minor Op.78https://music.youtube.com/watch?v=ZWCZq33BrOo&si=A7uooZ7N9HCELVTK

ReferencesGuerra, DJ. 2025. Unpublished lecturesJ Lipid Res. 2020 Feb 10;61(4):505–522Int J Mol Sci. 2022 Jul 8;23(14):7592.Dylan, B. 1975. Girl from the North Country. Nashville Skyline lp.https://music.youtube.com/watch?v=-PfDSQSWuGI&si=dXdXM6eQ9iUUoYJEFuray, R. 1971. Kind Woman. Pocohttps://music.youtube.com/watch?v=wO6iZ2C5Cac&si=4RujhChh5-5MmqUb

ReferencesJ Lipid Res. 2020 Feb 10;61(4):505–522Guerra, DJ. 2025. Unpublished LecturesHunter/Garcia. 1975. Dance A Holehttps://music.youtube.com/watch?v=pY0NthZp2So&si=YXLUMh-SAQyGvztU

ReferencesInt J Mol Sci. 2022 Jul 8;23(14):7592Health Sciences Review 2025 Volume 16, September 100232Mozart, WA. 1786. Piano Concerto 23 in A Major. . K488https://music.youtube.com/watch?v=BMYjGkgzinU&si=YrXsiXsH756bQiOx

ReferencesGenome Biology 2011. volume 12, Article number: 236.Genet Mol Biol. 2016 Aug 4;39(3):312–328.Nucleic Acids Res. 2008 Sep 4;36(17):5678–5694. EMBO J 2023 Feb 1;42(3):e111998Clapton, E. 1977. The Core. Slowhandhttps://music.youtube.com/watch?v=xutO4ZfkV3s&si=WYxhsl4hw0eCfRxOHunter/Garcia; Barlow/Weir 1973. Wake of the Flood lphttps://music.youtube.com/playlist?list=OLAK5uy_lD82hRPMacmRgwRiSljvVgZw-P4Ez7jos&si=vm1uUASx1Ir8AjZm

References EMBO J . 2023 Feb 1;42(3):e111998. Experimental & Molecular Medicine 2024. v.56,:1250–1262Genet Mol Biol. 2016 Aug 4;39(3):312–328. Ageing Res Rev. 2016 Mar 15;33:105–11PLoS Genet. 2010 Dec 2;6(12):e1001228Hendrix, J. 1967. Little Wing Derek and the Dominoes-Layla lp.https://music.youtube.com/watch?v=EOW9aixXnq4&si=oJfShR5rvxa7iJB1Dylan, B. 1967. All Along the Watchtower Jimi Hendrix Experiencehttps://music.youtube.com/watch?v=TLV4_xaYynY&si=55zsnL--bUcWYZSzZappa, F. 1975. Black Napkinshttps://music.youtube.com/watch?v=RfHT-T6R6WY&si=-hOcciVfN1pqky5_McTell, BW. 1928.Statesboro Blues. .Allman Brothershttps://music.youtube.com/watch?v=dWy3Q30Cn2A&si=L9DCovynACHVtb2-Pachelbel. , J. 1680 Canon in D.https://music.youtube.com/watch?v=lgh68Swuak0&si=DMo20XaV9hvhI8o3

ReferencesLeukemia 2010 volume 24, pages 679–686 Int J Biol Macromol. 2022 Jun 1;209(Pt A):1498-1503.Oncogene . 2013 Apr 4;32(14):1784-93.Cell. 2023 Sep 28;186(20):4404-4421.e20.Kirwan, D. 1971 Sands of Time. Fleetwood Machttps://music.youtube.com/watch?v=1Jkp34jMeEw&si=qqDnAKQley5G128- McVie, C. 1971. Show me a Smile. Fleetwood Machttps://music.youtube.com/watch?v=r6nEogq7pRQ&si=tkF_lSlZgWlqWgVXMydland, B. 1980. I Will Take You Home. Grateful Deadhttps://music.youtube.com/watch?v=gjBGVdsp8U4&si=8yjwxH53XiTA2La_Mozart, 1791. WA. Clarinet Concerto in A Major K.622https://music.youtube.com/watch?v=YT_63UntRJE&si=Vyvn9BHiY6s6zV4H

ReferencesMethods Mol Biol . 2021:2187:283-301.J Chromatogr A. 2017 Nov 24;1525:116-125.Front Neurol. 2020 May 21;11:437. Blood (2022) 140 (Supplement 1): 10027–10028.Hunter/Garcia; 1974. Live From the Mars Hotel lp.https://music.youtube.com/playlist?list=OLAK5uy_lbOpMMxw8R_c4rEUx7dUhselux-958NXg&si=opoQJxzJWcLFUPtG Vivaldi, A 1723-28 Concertos for two violins RV 505,515,519,530https://music.youtube.com/playlist?list=OLAK5uy_ncKKQdSHhUL8Bm-zqgSEhKXNKgoA8G-WI&si=t93wyzbWwJGkGPhy

Muscle isn't just about strength or performance — it's metabolic armor. In this episode of The Metabolic Link, Dr. Andy Galpin sits down with hosts Victoria Field and Dr. Dominic D'Agostino to show how muscle, cardio fitness, and bone density work together to protect against decline and extend healthspan. From women's training and recovery practices to kids in the weight room, Dr. Galpin translates decades of research into practical strategies anyone can use.Big questions Dr. Galpin helps answer:How does muscle mass protect against metabolic decline and early mortality?What's the safest, most effective on-ramp to rebuild bone density and explosiveness after 40?When is fasted training useful for women, and when is it counterproductive?How early can kids start resistance training — and what should it look like?Which recovery practices are underrated (free) versus overrated (pricey)?Dr. Andy Galpin is a tenured full professor and human performance scientist with a PhD in Human Bioenergetics and an MS in Human Movement Sciences. He previously ran the Center for Sport Performance and the Biochemistry & Molecular Exercise Physiology Lab at Cal State Fullerton, and now serves as Executive Director of the Human Performance Center at Parker University. He has authored over 50 peer-reviewed publications, coaches elite athletes across the UFC, NBA, MLB, NFL, Olympics, and special forces, and is the host of the Perform with Dr. Andy Galpin podcast, where he shares insights from two decades of working with world-class performers.Special thanks to the sponsors of this episode:✅Genova Connect – Get 15% off any test kit with code METABOLICLINK here!✅ Branch Basics - Get 15% off your Premium Starter Kit here✅ iRestore - Get a huge discount on the iRestore Illumina Face Mask when you use the code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.

In this episode of The Dairy Podcast Show, Dr. Corwin Nelson from the University of Florida takes a closer look at hypocalcemia and how our understanding of it has changed. He explains what's really driving calcium imbalances, how inflammation plays a role, and what producers can do with current feeding and management tools. Hear practical strategies to keep cows healthier after calving. Listen now on all major platforms!"Zeolite binders have been very effective at preventing hypocalcemia on farms, and the nutritionists using them seem genuinely satisfied with the results."Meet the guest: Dr. Corwin Nelson is an Associate Professor of Physiology at the University of Florida. He holds a Ph.D. in Biochemistry and Immunobiology from Iowa State University and a B.S. in Biochemistry from the University of Minnesota-Duluth. His research focuses on improving cattle health and productivity through better nutritional and immune system strategies.Liked this one? Don't stop now — Here's what we think you'll love!Dr. Michael Hutjens: Buffer Benefits for Dairy Cows | Ep. 58Dr. Michael Steele: Colostrum Feeding Strategies | Ep. 104Dr. Miguel Morales: Transition Cows & Calcium Balance | Ep. 126What you'll learn:(00:00) Highlight(01:37) Introduction(04:50) Hypocalcemia insights(07:48) Effects on cow health(15:05) Calcium monitoring strategies(20:02) Prepartum feeding tools(23:10) Transition cow health tools(27:37) Final three questionsThe Dairy Podcast Show is trusted and supported by innovative companies like: Protekta* Priority IAC* Evonik* Adisseo- AHV- dsm-firmenich- SmaXtec- Natural Biologics- Berg + Schmidt- ICC

ReferencesNeural Regen Res. 2026 Mar1;21(3):1037-1057. Cell Death & Disease 2018. volume 9, Article number: 670 Oncotarget. 2016 Apr 14;7(18):24995–25009. J Neurosci. 2016 Apr 20;36(16):4624–4634EMBO rep(2016)18: 48 - 60Trends in Endocrinol&Metabolism. 2013.ReviewVolume 24, Issue 12p635-643December Bruce&Bruce. 1977  Mammas Don't Let Your Babies Grow up to Be Cowboyshttps://music.youtube.com/watch?v=qZTwjljm5qc&si=SyK_xfigA9KvULG5Diddly, B. 1956. Who Do You Love? Pt 1 and 2. QMShttps://music.youtube.com/watch?v=SHxwNxXBEYo&si=8Vx-PT0jFZeBvQuKhttps://music.youtube.com/watch?v=urRksZiNVac&si=3nJ-uePAgJ6uzKVLHunter/Garcia. 1969. St. Stephen. Live Deadhttps://music.youtube.com/watch?v=xZ5TftMTPOE&si=qfOPM7TR02rMjwqg

This week we continue our fascinating conversation with biochemist, intelligent design advocate, and author Dr. Michael Behe, looking back over three decades since he first published Darwin's Black Box in 1996. On this episode, we will discuss some of the challenges facing origin of life research. From Michael's personal website: Michael Behe is Professor of Biological Sciences at Lehigh University in Pennsylvania and a Senior Fellow at Discovery Institute's Center for Science and Culture. He received his Ph.D. in Biochemistry from the University of Pennsylvania in 1978. Behe's current research involves delineation of design and natural selection in protein structures.In his career he has authored over 40 technical papers and two books, Darwin's Black Box: The Biochemical Challenge to Evolution and The Edge of Evolution: The Search for the Limits of Darwinism, which argue that living system at the molecular level are best explained as being the result of deliberate intelligent design. The books have been reviewed by the New York Times, Nature, Philosophy of Science, Christianity Today, and many other periodicals. Darwin's Black Box has sold over 250,000 copies and was internationally reviewed in over one hundred publications. Both National Review and World magazine named it as one of the 100 most important books of the 20th century.Behe has presented and debated his work at major universities throughout North America and England.More about Darwin's Black BoxAudio Clips Featured in the Broadcast:Paul Davies: https://youtu.be/q4LnWlOKQFA?si=92PafZrUWecexarMRichard Dawkins: https://youtu.be/HJY5KKDrygI?si=kIyKZjIP26qsoGKBJerry Coyne: https://youtu.be/QOsNhQeUwk0?si=_BS67GjvyjItxeCVFree Resources from Watchman Fellowship Naturalism: https://www.watchman.org/Naturalism/ProfileNaturalism.pdfScientism: https://www.watchman.org/scientism/ProfileScientism.pdfPanpsychism: https://www.watchman.org/files/ProfilePanpsychism.pdfPostmodernism: https://www.watchman.org/files/ProfilePostmodernism.pdfAtheism: https://www.watchman.org/profiles/pdf/atheismprofile.pdfAdditional ResourcesFREE: We are also offering a subscription to our 4-page bimonthly Profiles here: www.watchman.org/FreePROFILE NOTEBOOK: Order the complete collection of Watchman Fellowship Profiles (around 700 pages -- from Astrology to Zen Buddhism) in either printed or PDF formats here: www.watchman.org/NotebookSUPPORT: Help us create more content like this. Make a tax-deductible donation here: www.watchman.org/GiveApologetics Profile is a ministry of Watchman Fellowship For more information, visit www.watchman.org © 2025 Watchman Fellowship, Inc.

Dr. Gavin Davey, Associate Professor in Biochemistry, Trinity College Dublin, discusses new research which has found that minuscule pieces of waste plastic can damage our brains and may be contributing to the increasing global levels of Alzheimer's and Parkinsons.

ReferencesPharmaceuticals (Basel). 2010. Jan28;3(2):345–368.Neural Regen Res. 2026 Mar1;21(3):1037-1057. Sci Rep. 2020 Jul 28;10:12651Balin, M. 1967. Comin Back to Me Jefferson airplane Surrealistic Pillow. lphttps://music.youtube.com/watch?v=y2f3tlgApHw&si=uzI_8QNfUyLZ0wOZLouvin Bros. 1959. The Christian Life. on Sweetheart of the Rodeo. lphttps://music.youtube.com/watch?v=XpSgH5ooniE&si=nl7w4dIQMQYni_MPTeleman, GP. 1733. Tafelmusik Complete.https://music.youtube.com/watch?v=xNFkKhfdgZM&si=j087V7x5fig33T6h

In this powerful episode we speak with Dr. Aimie Apigian—double board-certified physician and author of The Biology of Trauma. Together, they explore how trauma is stored not only in the mind, but also in the cells and biology of the body, affecting everything from mental health to chronic fatigue and even fertility. Dr. Aimie shares her transformative personal journey from allopathic medicine to trauma healing, and how unresolved stress patterns manifest as physical symptoms like brain fog, hormone imbalances, and autoimmune conditions.Whether you're struggling with health issues, infertility, or burnout—or you're a practitioner supporting others—this episode sheds light on how to recognize, repair, and restore your biology from the inside out using an integrative mind-body-somatic approach.Key Takeaways:Trauma is stored in the cells and nervous system, not just the mind—affecting your energy, mood, and health.Stress and trauma are different states: stress is high-energy survival; trauma is shut down when the body feels it can't cope.Morning fatigue, brain fog, and emotional reactivity are signs your body may be stuck in a trauma response.Somatic practices can shift biology quickly, often more effectively than supplements or traditional therapy.True resilience is adaptability—the ability to meet change with flexibility, not by shrinking or avoiding.Dr. Aimie Apigian Bio:Dr. Aimie Apigian, MD, MS, MPH, is a double board-certified physician in Preventive and Addiction Medicine with advanced degrees in Biochemistry and Public Health. She is the founder of The Mind-Body-Biology Institute and creator of The Biology of Trauma®, a pioneering framework that integrates medicine, neuroscience, and somatic therapies to address how trauma is stored in the body—and how to heal it. Inspired by her personal journey as a foster and adoptive mother, Dr. Aimie blends rigorous science with deep compassion to help individuals and practitioners achieve lasting transformation. Her book, The Biology of Trauma, reveals the cellular and emotional roots of fear, pain, and overwhelm, and offers a practical path to true mind-body-biology healing.Where to find Dr. Aimie Apigian:Instagram: https://www.instagram.com/draimie/LinkedIn: https://www.linkedin.com/in/dr-aimie-apigianYouTube: https://www.youtube.com/c/DrAimieApigianWebsite: https://biologyoftrauma.com/Podcast: https://biologyoftrauma.com/biology-of-trauma-podcast/Book: https://book.biologyoftrauma.com/landing-page***** I am giving away my 5 Day Nervous System reset, a Masterclass on the book and the 1st three chapters of my book to those who pre-order the book now. *** How to connect to Lorne Brown online and in person (Vancouver, BC)

Minuscule pieces of waste plastic, thousands of times smaller than a human hair, can damage our brains and may be contributing to the increasing global levels of Alzheimer's and Parkinson's disease. That's according to new research led by Dr Gavin Davey, From the School of Biochemistry and Immunology, Trinity College Dublin who spoke to Newstalk Breakfast.

ReferencesBiointerphases 2023. 8 Issue 3, Biophys J. 2023.v 122, Issue 21 p4144-4159 November 07Guerra, DJ. 2025. Unpublished LecturesKahn and Van Heusen. 1960. Aint That a Kick in the Head. Dean Martinhttps://music.youtube.com/watch?v=_dvRf10od3E&si=HwInnwUdt4xy1NDTWarren and Brooks. 1953. That's amore. Dean Martinhttps://music.youtube.com/watch?v=RUz1pZ_LujU&si=cYeJjpn_2PPPLZkrUnknown. late 11th century. Gregorian Chant-Templarshttps://music.youtube.com/watch?v=K16M-z9rfJo&si=h_VAqt2he03JjoHD

ReferencesJ Neurochem. 2009 May;109(Suppl 1):160–166.BMB Rep. 2018 Jan 31;51(1):5–13Neuroscience Letters 2008. 444:264-269.FASEB J 2003.17:1954-1956.Acta Neuropathol 2010. 119:389-408.Int J Mol Sci. 2024 Feb 17;25(4):2364. Van Zant and Rossington. 1973. Simple Man. Lynard Skynardhttps://music.youtube.com/watch?v=8eNoms9wsGc&si=XmGHJst1qhxVAsfzHaggard, M. 1968.Mama Triedhttps://music.youtube.com/watch?v=XyRCvukVv6w&si=TEL39MK2h2OyZzpuWinwood and Miller. 1967. Im A Man. Chicago Transit Authority.https://music.youtube.com/watch?v=cBGyFrHF1eU&si=pSX1ETJ-Rcz0cuthBeethoven. LV 1808. Symphony V in C MInor. Op 67.https://music.youtube.com/playlist?list=OLAK5uy_liyV_UqDxfyalYOph73txH8WytxBpnns0&si=OigyPVh6EXVExYNT

ReferencesGuerra, DJ. 2025. Unpublished lectures Boccherini, L. 1765. Cello Concerto No. 9 in B-flat Major, G. 482,Haydn, FJ. 1792. Symphonie Concertante in B flat OP. 84.https://music.youtube.com/playlist?list=OLAK5uy_nqMsdDwKlHHVmWylw6kQsoBSwQMsCitm8&si=D23Iqly4ef6Ej1m7

What does it really mean to be a professional in the pet care industry? In this episode, Jenn Dahinten, Chair of PACCC, joins to explore the importance of third-party certification in setting industry standards. She shares how PACCC was founded to support experienced pet care providers with recognition, ethics, and continuing education. The conversation dives into the rising pressure from legislation, public expectations, and why certification helps build trust with clients and lawmakers alike. Jenn also offers practical steps for those ready to elevate their professionalism. Main topics: Third-party certification vs. online courses Legislative pressure and industry regulation Career progression in pet care The role of ethics and continuing education How professionals can influence legislation Main takeaway: “There is a skill set, both taught and intuitive, that's required to provide care for a pet when their owner is away.”– Jenn Dahinten Too often, pet care is seen as simple or instinctual—just for “animal lovers.” But Jenn Dahinten reminds us that caring for someone else's pet isn't the same as caring for your own. It demands education, experience, and emotional intelligence. Certification through PACCC proves that you take your role seriously, and that you're committed to excellence in your profession. When pet parents leave their pets in our care, they deserve nothing less than a certified professional. About our guest: Jenn Dahinten became the owner, and operator of Royal Pets Hotel and Enrichment in 2009 and founded the charitable “Racers Fund”, for retired service dogs shortly after. Having been a pet parent and client of pet care facilities on four different continents she relished the opportunity to provide the kind of loving care, expertise, and professionalism that she always felt our fur family deserved. Before joining the pet care industry, Jenn first was a paramedic (human). Jenn studied Biochemistry at the University of Guelph, Ambulance and Emergency Care at Conestoga College, and then Advanced Life Support Paramedic (L3) at the University of Natal. During her years of providing air/ground emergency care across continental Africa, Europe, and the UK, Jenn was also active in providing veterinary assistance at local small animal practices and shelters. During a subsequent career in pharmaceutical sales, marketing, and training, Jenn returned to Canada and discovered her calling in the pet care and education industry. From the start, Jenn has been an advocate for fear free practices across grooming and training and has ensured that Royal Pets has been at the forefront of setting the standard in pet care. Royal Pets has been a part of both the IBPSA and The Dog Gurus since their inception and is proud to be an active member of the APDT, Fear Free ™ Organization, and PACCC. Jenn continues to provide education and training opportunities locally and within her industry and continues to champion continuing education, certification, regulation, and professionalism as some of the many necessary means to guarantee our pets get the care and attention they deserve. Links: PACCC: https://PACCERT.ORG Check out their Facebook: https://www.facebook.com/pacccsocial Alabama Legislation: https://www.billtrack50.com/billdetail/1885956 Check out our Starter Packs See all of our discounts! Check out ProTrainings Code: CPR-petsitterconfessional for 10% off

References The Journal of Physical Chemistry 2024. BVol 128/Issue 51 Article B: Biophysical and Biochemical Systems and Processes December 13.EPUB: Neural Regen Res. 2025 Apr29;21(3):1037–1057.Final Pub: Neural Regen Res. 2026 Mar1;21(3):1037-1057. Guerra, DJ. 2025. Unpublished Lectures.Lennon/McCartney, Harrison. 1968. Magical Mystery Tour lp.https://music.youtube.com/playlist?list=OLAK5uy_kxk_lSv8ZOf-eZeqp627XdaEIOozc34Ec&si=O2BHXjB9ht2HUIDhDylan, B. 1969. Girl From the North Country w/ Johnnie Cashhttps://music.youtube.com/watch?v=-PfDSQSWuGI&si=pBmK9LyFuaBH292nHunter/Garcia. 1972. Tennessee Jedhttps://music.youtube.com/watch?v=K5KEQ-sC6vg&si=dGEOG7BjzmMnbcbl

What if hair loss was really a signal from your body, not just a cosmetic issue?In this episode, I talk with VJ Hamilton, The Autoimmune Nutritionist, about overcoming alopecia areata and other forms of hair loss by addressing root causes. We dive into nutrient deficiencies, gut health, thyroid imbalances, and inflammation and how functional medicine can help hair grow back naturally.If you've been told there's no hope for hair loss, this episode will challenge that belief.Episode Timeline: 00:00 – Episode Preview02:07 – Podcast Intro02:32 – Meet VJ Hamilton, Autoimmune Nutritionist04:02 – VJ's Story: Alopecia at Age 705:24 – Reversing Fatigue, Psoriasis, and Chronic Issues08:55 – Hair Loss: Autoimmune vs. Other Causes12:58 – Hair Regrowth: Healing Timeline16:09 – Inflammation Triggers: Gut, Scalp, Whole Body18:12 – Five Key Hair Loss Markers25:44 – Biotin: Overrated or Essential?27:50 – Nutrients: Selenium, Vitamin A, Genetics31:29 – Low Stomach Acid and Absorption33:01 – Supplements vs. Food for Hair Growth35:05 – First Steps with Hair Loss Diagnosis36:07 – Complex Cases: Mold, Toxins, Nervous System39:25 – Connect with VJ Hamilton Online40:42 – Podcast Outro41:03 – Root Cause Healing: Final TakeawaysAbout VJ Hamilton:VJ Hamilton, also known as The Autoimmunity Nutritionist, is the founder of The Autoimmune Nutrition Clinic and a Registered Nutritionist specialising in reversing hair loss, particularly alopecia areata, and other autoimmune-related conditions. With a Medical Science degree (BSc) in Biochemistry & Immunology and certification from the Institute for Functional Medicine, VJ combines scientific expertise with lived experience to deliver evidence-based, personalised therapies. Connect with VJ Hamilton:VJ Hamilton's Website: https://theautoimmunitynutritionist.com VJ Hamilton's FB Page: https://www.facebook.com/A.Nutritionist/ To take the Save My Thyroid Quiz visit www.savemythyroid.com/quiz Free resources for your thyroid health Get your FREE Thyroid and Immune Health Restoration Action Points Checklist at SaveMyThyroidChecklist.com High-Quality Nutritional Supplements For Hyperthyroidism and Hashimoto' sHave you checked out my new ThyroSave supplement line? These high-quality supplements can benefit those with hyperthyroidism and Hashimoto's, and you can receive special offers, along with 10% off your first order, by signing up for emails and text messages when you visit ThyroSave.com. Do You Want Help Saving Your Thyroid? Click Here to access hundreds of free articles and blog posts. Click Here for Dr. Eric's YouTube channel Click Here to join Dr. Eric's Graves' disease and Hashimoto's group Click Here to take the Thyroid Saving Score Quiz Click Here to get all of Dr. Eric's published booksC...

ReferencesMol Neurobiol. 2019 Oct 8;57(2):910–925.Neural Regen Res. 2025 Apr 29;21(3):1037–1057.Open Biol. 2017 May 31;7(5):170069.Neurobiology of Disease 2025. v.207, April , 106852Chamber, W&J.1966 Time Has Come Today. Chambers Brothers. https://music.youtube.com/watch?v=4GPh7PLjUs4&si=N42P6DJJBBOjbPIrRagovoy and Meade. 1963. Time is on my Side. Rolling Stones.https://music.youtube.com/watch?v=ZHKz7FBUF1w&si=GdRI9xB7q_pOWY9vRogers/Slade/Mann 1975.Time is Right. Manfred Mannhttps://music.youtube.com/watch?v=WKtbbCB0Nm8&si=2J5ef4X0zO-PrKRVWaters/Gilmour/Mason/Wright 1973. Time. Pink Floyd. DSotMhttps://music.youtube.com/watch?v=yl-Ms_ek-kE&si=44M9K5WUf24LssAO

On the last two episodes of AP, we talked with Tricia Scribner about how theistic evolution impacts how we understand the God of the Bible. On the next two episodes, we will be following up with a conversation with biochemist Dr. Michael Behe, author of his widely popular 1996 book Darwin's Black Box. We will delve into the challenges molecular design and structure within living cells poses to traditional Neo-Darwinian concepts of evolution by means of natural selection and discuss how Dr. Behe believes intelligent design is the better scientific hypothesis. From Michael's personal website: Michael Behe is Professor of Biological Sciences at Lehigh University in Pennsylvania and a Senior Fellow at Discovery Institute's Center for Science and Culture. He received his Ph.D. in Biochemistry from the University of Pennsylvania in 1978. Behe's current research involves delineation of design and natural selection in protein structures.In his career he has authored over 40 technical papers and two books, Darwin's Black Box: The Biochemical Challenge to Evolution and The Edge of Evolution: The Search for the Limits of Darwinism, which argue that living system at the molecular level are best explained as being the result of deliberate intelligent design. The books have been reviewed by the New York Times, Nature, Philosophy of Science, Christianity Today, and many other periodicals. Darwin's Black Box has sold over 250,000 copies and was internationally reviewed in over one hundred publications. Both National Review and World magazine named it as one of the 100 most important books of the 20th century.Behe has presented and debated his work at major universities throughout North America and England.More about Darwin's Black BoxAudio Clip of Kenneth Miller Featured in the Beginning: https://youtu.be/c_qNaCff7JY?si=bjypBWctbLTvlucZFree Resources from Watchman Fellowship Naturalism: https://www.watchman.org/Naturalism/ProfileNaturalism.pdfScientism: https://www.watchman.org/scientism/ProfileScientism.pdfPanpsychism: https://www.watchman.org/files/ProfilePanpsychism.pdfAtheism: https://www.watchman.org/profiles/pdf/atheismprofile.pdfAdditional ResourcesFREE: We are also offering a subscription to our 4-page bimonthly Profiles here: www.watchman.org/FreePROFILE NOTEBOOK: Order the complete collection of Watchman Fellowship Profiles (around 700 pages -- from Astrology to Zen Buddhism) in either printed or PDF formats here: www.watchman.org/NotebookSUPPORT: Help us create more content like this. Make a tax-deductible donation here: www.watchman.org/GiveApologetics Profile is a ministry of Watchman Fellowship For more information, visit www.watchman.org © 2025 Watchman Fellowship, Inc.

ReferencesNeuron 2015. Vol 85, Issue 4, 18 February Pages 695–702Neural Regen Res. 2025 Apr 29;21(3):1037–1057.Front Mol Neurosci. 2018 Jan 23;11:10Nature Reviews Neuroscience 2025 Ve 26, pages214–231 Mozart, WA. 1778. Violin Sonata No. 18 in G Major, K.301/293ahttps://music.youtube.com/watch?v=szu13HgqGZk&si=OQbazVhvLYS6R12oMozart, WA. 1781. Violin Sonata 27. in G major.. K379https://music.youtube.com/watch?v=VLod_2Sszhk&si=AZvfjkfMQoSQRdEx

On this episode of Skin Anarchy, host Dr. Ekta sits down with Kat Burki to explore biochemistry as a smarter approach to skincare formulation. With a background spanning epidemiology and healthcare, Kat brings a unique lens to beauty: treating the skin as a living organ with its own complex needs.What makes her philosophy stand out is the insistence on synergy. Rather than chasing “hero ingredients,” Kat focuses on how ingredients interact—pairing vitamins, peptides, and cofactors in ways that mirror how the body naturally processes them. She emphasizes that delivery systems and supportive bases are just as important as what's in the formula. For Kat, skincare is about networks of ingredients working together, not isolated actives.Listeners will also hear her perspective on the skin's own microbiome, and why protecting its balance is critical to resilience and long-term health.From her cult-favorite Vitamin C Intensive Face Cream to her innovative focus on scalp health, Kat shares how biochemistry can transform not just product design but the way we think about skin itself. She leaves us with practical advice: read labels wisely, look for biome support, and always ask whether a formula makes biological sense. Tune in to discover how skincare can move beyond hype to real healing with Kat Burki.To learn more about Kat Burki, visit her website and social media. CHAPTERS:(0:00) Introduction & Guest Welcome(0:51) Kat's Background & Path to Skincare(1:48) Gut Health, Nutrition & Skin Connection(4:13) Nutritional Biochemistry & Skincare Synergy(7:22) Misconceptions in Nutrition & Topical Delivery(9:02) Formulation Philosophy & Product Design(12:04) Biome-Focused Products & Healing Approach(14:03) Vitamins, Co-Factors & Biotech Trends(16:25) Peptides, Hype & Real Science(22:03) Brand Philosophy, Labs & First Hero ProductPlease fill out this survey to give us feedback on the show!Don't forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform.Reach out to us through email with any questions.Sign up for our newsletter!Shop all our episodes and products mentioned through our ShopMy Shelf! Hosted on Acast. See acast.com/privacy for more information.