Podcasts about Biochemistry

“At some point, feeling good wins over old thoughts.” –VJ HamiltonStruggling with autoimmune disease — or uncomfortable symptoms that you've just learned to live with? What if you could reverse your symptoms? I'm so excited to talk with VJ Hamilton, registered nutritionist and a functional medicine practitioner who specializes in autoimmune disease.I was diagnosed with celiac disease fairly late in life. When I was diagnosed, it just made so much sense and explained so many things. It also led to change. And that can be hard to navigate on your own.Perimenopause and menopause symptoms and those of autoimmune diseases — like brain fog, joint aches, and fatigue — can be signs of both. Plus shifts in hormones can certainly trigger changes or unmask hidden inflammation. Testing and treatment can help.We talk about: Autoimmune disease 101 — what we're actually talking aboutTriggers vs. root causes and how to find the root causeHow to advocate for yourself with doctors and what other practitioner you might want to seeSimple changes you can make to improve your healthFocus not on what you have to cut out for food or what exercise you have to do, but what you need and what you likeEating whole foods instead of prepared meals and how to navigate restaurants and special eventsABOUT VJVJ Hamilton is the founder of The Autoimmunity Nutritionist and an expert in autoimmune disease, specialising in skin disorders, chronic fatigue, joint health, and digestive issues for both men and women.As a Registered Nutritionist with a Medical Science degree (BSc) in Biochemistry & Immunology and having completed the full certification programme at the renowned Institute for Functional Medicine, VJ uses evidence-based nutritional therapies to support her clients in transforming their health.LINKShttps://theautoimmunitynutritionist.com/https://www.instagram.com/theautoimmunitynutritionist/ https://www.linkedin.com/in/theautoimmunitynutritionist/ DOABLE CHANGESAt the end of every episode, we share three doable changes, so you can take what you've heard and put it into action. Action is where change happens. But here's the thing: when we have a goal, a wish, a desire bubbling up in us, it can feel really huge. Sometimes we stop ourselves in our tracks based on how huge our desire feels. Change needs action, but it doesn't need huge action. When we focus on the next step, the next Doable Change that we can integrate into our lives, we don't get stuck and we create momentum. Choose one Doable Change that resonates with you today and really play with it. Fit it into your life, your days, make it work for you — then move on to your next Doable Change. Here are Three Doable Changes from this conversation: MAKE A LIST OF THINGS YOU LOVE TO DO. Changing your lifestyle doesn't have to be terrible! Make a list of things you love to do. Ways you like to be active, rest, connect with others. Make a list of things that make you feel good! Plan for more of those things in your life. That might look like swapping dancing for a gym session or eating food that gives you energy or going to bed on time.RESET IDEAS AROUND FOOD. Here are a few ways to try this Doable Change. First, instead of asking, “What do I have to cut out?” think about what foods you can...

ReferencesProc Natl Acad Sci U S A. 2023 Jan30;120(6):e2219630120.Cells. 2023 Mar 14;12(6):896Guerra, DJ. 2025. Unpublished LecturesHunter, R. 1974 Tales of the Great Rum Runnershttps://music.youtube.com/watch?v=E7Dc_cJQzKw&si=EpCSXN61dFWr5K0ZIbid. Dry Dusty Road.https://music.youtube.com/watch?v=Jj7VoM6LvVw&si=U1geVxRp_-5ZYtFRMozart, WA, 1778. Concerto for Flute Harp and Orchestra in C Major K.299https://music.youtube.com/watch?v=nheif2BuFz0&si=NKLWDFAzlA8ztX8e

ReferencesProc Natl Acad Sci U S A. 2023 Jan30;120(6):e2219630120.Curr Hypertens Rep. 2018 Mar 19;20(3):20. FEBS Open Bio. 2022 Dec 1;13(1):185–194Biophys J. 2023 Apr 24;122(12):2381–2382 Lamb et al. 1970. Chicago II.https://open.spotify.com/album/0PRgsdDXQ8QPaDUetVF7yN?si=w4rzfSUkSlmq03nqYXDNlg

In this thought-provoking episode of The Lebanese Physicians Podcast, we sit down with Dr. Rose Mary Boustany, Professor of Pediatrics and Biochemistry at the American University of Beirut, and a pioneering figure in neurogenetics and autism research. Together, we explore the complex roots of autism from genetic and epigenetic influences to environmental and neurobiological factors and discuss how these discoveries are transforming both research and care. Dr. Boustany reflects on her decades-long journey in pediatric neurology, the evolution of autism understanding worldwide, and the pressing need for global collaboration to bridge scientific gaps. The conversation also tackles common myths about autism's causes, and how deeper scientific insights can enhance early diagnosis, intervention, and compassionate care for families. Join us as we go beyond the headlines to unpack the science, the challenges, and the promise of future breakthroughs in autism research   #AutismResearch #Neurogenetics #LebanesePhysiciansPodcast #GeneticsAndEnvironment #Epigenetics #PediatricNeurology #AutismAwareness #GlobalHealth #Neuroscience #MedicalInnovation #LebanesePhysicians #HealthPodcast Available on all podcast apps and on YouTube

ReferencesBiophys J. 2016 May 10;110(9):2053–2065. Eur Phys J E Soft Matter. 2023 May30;46(6):37. Data Brief. 2015 Oct 26:5:537-41.Guerra, DJ. 2025 Unpublished LecturesLightfoot, G. 1975. Canadian Railroad Trilogyhttps://music.youtube.com/watch?v=PXzauTuRG78&si=5b18gNKviXE1R1pUJagger/ Richards. 1971. Dead Flowershttps://music.youtube.com/watch?v=Avrv8t_nEI0&si=aqh2T88idTE4R487Jagger/Richards.1971. Moonlight Milehttps://music.youtube.com/watch?v=qpB8XyFSY5E&si=i9_eS4XdduP2Qqf_Dvorak, A. 1880. Twilight Way Op55https://music.youtube.com/watch?v=EQ-mV6upgMs&si=Klq7JAAdJ_K0WN8v

ReferencesMolecular Neurodegeneration 2012. v. 7, Article number: 45 Regul Toxicol Pharmacol.2017 Oct:89:165-185. Immunol Res 2020 Feb;68(1):28-38. J Biol Chem. 2019 Jun 7;294(23):9213-9224Guerra, DJ. 2025. Unpublished LecturesParsons, G. 1973. Brass Buttons Pocohttps://music.youtube.com/watch?v=CpFytplzLhI&si=zh_BXcVAmduzg7_hZevon/Wachtel/Marinell. .1978 Werewolves of Londonhttps://music.youtube.com/watch?v=lh0w01S7Jnk&si=y-NL0k9D921FLcqjSchubert, F. 1824. String Quartet 13 in A Minor D.804.https://music.youtube.com/watch?v=JGO_qd4PTh4&si=HkM17CiHNuTdEYrF

ReferencesStroke. 2025. Vol. 56 Issue 6, pp. 1625–1630, Immunol Res 2020 Feb;68(1):28-38Guerra. DJ 2025. Unpublished LecturesBiber HIF von. .1676. Violin Sonatashttps://music.youtube.com/playlist?list=OLAK5uy_mkzudfkd46I7zmmdR18QHrWocVrEXGzpk&si=hK-x20d5HZ8YhZjPLennon/McCartney. 1967. Penny Lane. Beatles.https://music.youtube.com/watch?v=vfxQ1oDiEJM&si=PrmwJkB6sh0ylese

ReferencesDiabetes Metab 2008 Dec;34(6 Pt 2):649-57. Biomedicines. 2023 Dec 12;11(12):3280 J Lipid Atheroscler. 2024 May;13(2):139-154Guerra, DJ. 2025. Unpublished LecturesSchubert, F. 1826. Symphony 9 in C Majorhttps://music.youtube.com/watch?v=Ip06DEeY_U8&si=OhfknGlCaihSClJd

ReferencesInflamm Regen. 2020 Feb 7;40:2.Arteriosclerosis, Thrombosis, and Vascular Biology 2019Volume 39, Number 3 Mar;39(3):432-445J Clin Endocrinol Metab. 2022 Mar 29;107(7):1956–1964.Guerra, DJ. 2025 Unpublished lecturesClark and Hatch. 1965. You're the One. The Vogueshttps://music.youtube.com/watch?v=zoQk_Dqg4WA&si=hYlyCYjGZlxNPyPvTownsend, P. 1973. I'm One https://music.youtube.com/watch?v=y2v6_0qNFfo&si=rbhXnkw5ocA1PclVBrown, Callili and Sandstone. 1966. Don't walk Away Renee. The left Bankehttps://music.youtube.com/watch?v=qDfrW5cWqMU&si=6Y3obqGZ5bfdVaC6Soriano, F. 1619. Salve Reginahttps://music.youtube.com/watch?v=qlnC-SP4MeQ&si=mkIiN3XUiIY8XXwb

ReferencesFront. Med. Technol., 06 April 2022Front Cell Dev Biol. 2023 Feb 8;11:1076250.Guerra, DJ. 2025. Unpublished LecturesMcTell, BW., 1928. Statesboro Blues. Allman Brothershttps://music.youtube.com/watch?v=vnk0jijQVK4&si=chL4h_xzd2tnYIZUBredon, A. 1958. I'm Gonna Leave You. LZhttps://music.youtube.com/watch?v=UyOg0mt2R2k&si=F3PLI_df7B01KLwh

ReferencesGuerra, DJ.2025 Unpublished LecturesMozart, WA. 1780's Serenades. a collectionhttps://music.youtube.com/playlist?list=OLAK5uy_m2t3TW8oRfCideAaHxTc3JH_dEFyZNo8g&si=UFZO5BZ_d4m-gXF9

Been wondering what to believe about acetaminophen? It's found in many over-the-counter products, not just Tylenol. Guest Dr. Christina Parks earned a double major in Biochemistry and Molecular Biology and Chemistry Honors and a Ph.D. in Cellular and Molecular Biology. As an educator, she helps us all understand the science so we can make informed decisions.Reference Linkshttps://informedchoicewa.substack.com/https://www.vi-ta.org/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

ReferencesCold Spring Harb Perspect.Biol. 2018 Feb; 10(2): a028415.Sci. Signal. 2019;12:eaau2293Stem Cells Int. 2017 Aug 16;2017:2193432Proc Natl Acad Sci U S A. 2023 Jan30;120(6):e2219630120Hunter Garcia. 1975. Franklin's Tower .Blues for Allah. Grateful Deadhttps://music.youtube.com/watch?v=55TOIJxKc74&si=gZFUTJv8Ju2XlPBFBill KreutzmannBob WeirJerry GarciaKeith GodchauxMickey HartPhil LeshDonna GodchauxRobert Hunter 1975 Sandcastles, Glass Camels and Unusual Occurences in the Desert. Blues for Allah. Grateful Dead.https://music.youtube.com/watch?v=puKdKkCA2Ik&si=e15ow1HA_e6fHyvq

ReferencesFront Cardiovasc Med. 2024 May 13;11:1386733.Eur J Heart Fail . 2021 Jun;23(6):895-905Simon, P. 1970. The Boxer S&Ghttps://music.youtube.com/watch?v=l3LFML_pxlY&si=2ggC3NegOGRFoOk5Bach, JS 1721. Brandenburg Concerto IV. BMV 1049.https://music.youtube.com/watch?v=tp_WeHUKoXM&si=3nyiFKnvrdT71DW6Telemann, GP, 1720 Oboe Concertihttps://music.youtube.com/watch?v=n8XQh78MxqY&si=ryG3pBNefaNHlHG2

ReferencesCompr Physiol. 2013 Apr;3(2):785–797. Biochimica et Biophysica Acta(BBA) - Molecular Basis of Disease 2015.Volume 1852, Issue 3, March: 421-428Guerra, DJ. 2025. Unpublished LecturesJ Zhejiang Univ Sci B. 2005 Oct 28;6(11):1045–1056McCray, L. 1993 Soulshine. Allman Brothershttps://music.youtube.com/watch?v=UcAmXagv90k&si=s2eYW0sranydR9bSAllman, D. 1971. Little Martha. Eat a Peach lp. Allman Brothershttps://music.youtube.com/watch?v=typ2c8JPkLE&si=aFzABlZ3E5WH9pGu

ReferencesBrain and Cognition 2017. V. 113, April: 10-22J Mol Med (Berl). 2012 Feb;90(2):119-26Molecular Medicine Reports 2015. January 14: 3203-3211Guerra, DJ. 2025. Unpublished Lectures.Joel, B. 1977. The Strangerhttps://music.youtube.com/playlist?list=OLAK5uy_mLHjM5NsmwIHi3xPaTwme_7YCcgSTjafo&si=yNsqCp_8TPvNT_l9

David Traylor has 2 undergrad degrees in Bio-Chemistry and Molecular Biology. He is a former pro lacrosse player. He got involved in BioTech in the 1990's and dealt with the difficulties of getting molecules like erythropoietin to market at scale. From there he got into investment banking. Obviously, with that background, the next step is to do cannabis deals on 6 of the 7 continents!Golden Eagle Partners was the first investment banking firm to jump into cannabis, which they did in 2013. In addition to doing international cannabis deals, David's experience has led him to be involved with financial and cannabis related conferences around the world. In fact, David is the reason our co-host Trevor was at CannMed 23 in Florida.Listen as Trevor and David discuss: What is THC+ and THC-? Where is the cannabis industry going in the next three years? Did Canada blow it on the business side of cannabis when all that money poured in post national legalization in 2018? Why is it so hard to scale a biological product like cannabinoids?David wraps up with talking about the importance of humility when dealing with cannabis. Whether that is dealing with patients, growing the plant or navigating the cannabis business world, we think a reminder to be humble is a wonderful mantra!Golden Eagle Partners- websiteDavid Traylor - LinkedInMusic by:Hearty Har -Scream and Shout - YouTubeAdditional Music:Desiree Dorion desireedorion.comMarc Clement - FacebookTranscripts, papers and so much more at: reefermed.ca

Episode 208: Nitric Oxide - The Missing Link in Thyroid & Chronic Disease with Dr. Nathan Bryan In this episode, Dr. Eric Balcavage is joined by nitric oxide researcher and author Dr. Nathan Bryan, whose new book The Secret of Nitric Oxide explores why this tiny signaling molecule may be the key to preventing and reversing chronic illness. Together, they dive deep into: What nitric oxide is and why it's foundational for human health. How nitric oxide is made in the body—through both enzymatic and dietary pathways. The connection between nitric oxide, inflammation, oxidative stress, and the Cell Danger Response (CDR). How nitric oxide influences thyroid hormone production, conversion (T4 → T3), and the rise of reverse T3. Why loss of nitric oxide is one of the earliest triggers in chronic disease, including Hashimoto's, cardiovascular disease, Alzheimer's, and more. Common disruptors of nitric oxide production—nutrient deficiencies, environmental toxins, poor lifestyle habits, and even fluoride exposure. Practical steps to restore nitric oxide production naturally for better thyroid, metabolic, and overall health. This is a powerful conversation that reframes nitric oxide not as just a cardiovascular molecule, but as a master regulator of cellular health, energy production, and thyroid physiology.

  Dr. Valerie Akinwande is the founder of WomansDPT, a telehealth and mobile (concierge) pelvic floor practice. She earned Doctorate in Physical Therapy, a Master of Science in Biology and Biochemistry, and a Bachelor’s in Biology. Dr. Akinwande also taught … Continue reading →

ReferencesArch Gen Psychiat, 48 (1991), pp. 563-568Magnetic Resonance Spectroscopy in Psychiatric Brain Disorders, American Psychiatric Press, Washington DC (1994), pp. 49-83Biological Psychiatry 2002. 52, Issue 8, 15 October:823-830J Neuroinflammation. 2025 May 28;22:144. Guerra, DJ. 2025. Unpublished Lectures.Hunter/Garcia. 1970. Brokedown Palace.https://music.youtube.com/watch?v=gzRboWH1E6Y&si=RHYn8ej-BZsSKbo4Schubert, F. 1819. Quintet in A Major. D.667. OP.114https://music.youtube.com/watch?v=g3k81__bwrM&si=Xdl70V7tGPyReCt0

ReferencesCurrent Problems in Surgery 2025. Volume 68, July . 101768Stroke: Vascular and Interventional Neurology 2022 Volume 3, Number 2Guerra, DJ. 2025. Unpublished Lectures Simon, P. 1966. Leaves That Are Green. S&G.https://music.youtube.com/watch?v=OTlpdCPrx14&si=xcqpbcW8tNGWZGSxNorth and Zaret. 1965. Unchained Melody. Righteous Brothershttps://music.youtube.com/watch?v=te51eVrFWEc&si=n3MsJJ7oZ1uShcgGLightfoot, G. 1975. Don Quixotehttps://music.youtube.com/watch?v=LJB0nCv0qxk&si=0iootaOq9zbdCXy6Beethoven, LV, 1805. Piano Sonata No. 23 in F minor, Op. 57 "The Appassionata"https://music.youtube.com/watch?v=E5JObP74jcw&si=fZxyvFQuEOY-Q-Dm

ReferencesInternational Journal of Molecular Sciences2017. 18(7):1386Int J Mol Sci . 2022 Jul 12;23(14):7697.Sci Rep. 2020 Oct 20;10:17776Mol Cell. 2024 Apr 4;84(7):1338-1353.e8. Cell Metab. 2018 Sep 4;28(3):504-515.e7.Alcohol, 2017-12-01, Volume 65, Pages 51-62Neuroscience, 2023-11-21, Volume533, Pages 22-35Guerra, DJ. 2025 Unpublished Lectures Mozart WA. 1788. Divertimento E Major. K563.https://music.youtube.com/watch?v=E8c83bpOVXo&si=6EG2xcDaB9-c-mBQ

Send us a textThe biological roots of sleep are tied to mitochondrial metabolism.Episode Summary: Dr. Gero Miesenböck discusses the evolutionary and metabolic basis of sleep, exploring how mitochondrial energy production in neurons, particularly in fruit flies, drives the need for sleep to manage harmful byproducts like reactive oxygen species and lipid peroxides. They discuss how sleep-inducing neurons sense these byproducts, the role of mitochondrial dynamics, and the broader implications for why all animals, from jellyfish to humans, require sleep. The conversation also touches on how body size and metabolism influence sleep needs across species.About the guest: Gero Miesenböck, MD is a professor of physiology at the University of Oxford, renowned for his pioneering work in optogenetics and his research on the neurobiology of sleep using fruit flies and mice.Discussion Points:Sleep is universal across animals, even in jellyfish without centralized brains, suggesting a fundamental metabolic purpose tied to mitochondrial energy production.Mitochondria produce energy efficiently using oxygen but generate reactive oxygen species that can damage cells through lipid peroxidation, necessitating sleep to repair this damage.Sleep-inducing neurons in fruit flies contain sensors that track lipid peroxidation products, acting like a digital memory to signal when sleep is needed.Smaller animals with faster metabolisms, like mice, require more sleep and have shorter lifespans due to higher oxygen consumption and oxidative stress.Mitochondrial diseases in humans often cause intense tiredness, likely due to increased electron leaks in the mitochondrial energy production process.The evolutionary origin of sleep likely stems from the oxygen revolution 2.5 billion years ago, enabling complex life but requiring mechanisms like sleep to manage metabolic side effects.Caloric restriction reduces sleep need by lowering the production of harmful metabolic byproducts, supporting the link between metabolism and sleep.Reference paper:Study: Mitochondrial origins of the pressure to sleepRelated content:M&M 12: Organisms, Cities, Companies & the Science of Scale | Geoffrey West*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

ReferencesNeuroscience, 2023-11-21, Volume533, Pages 22-35Autophagy. 2021 Dec;17(12):3992-4009Cell Death Discovery 2024.  volume 10, Article number: 200 Autophagy. 2022 Apr;18(4):726-744Guerra, DJGPhD. 2025. Unpublished LecturesRafferty, J. 1977.Baker Street.https://music.youtube.com/watch?v=Fo6aKnRnBxM&si=lYDwqknKv1Du18CrSimon, P. 1963 Bleeker St. from Wed Morning 3AM; lp. Simon and Garfunkelhttps://music.youtube.com/watch?v=xcXoGTACMHA&si=Wr55-ahAtcayIAPGPrine, J. 1971. Hello in Therehttps://music.youtube.com/watch?v=RfwGkplB_sY&si=l-PjfRcedC67wFg-John, E.1972. Mona Lisas and Madhattershttps://music.youtube.com/watch?v=feMawHOpamI&si=c_1Cbf5YJIx8cJMj

ReferencesNeuroscience, 2023-11-21, V.533, Pages 22-35Pharmacological Research 2025.Volume 214, April 107685Front Neurol. 2022 Apr.11;13:804851.Rossini, G. 1829. William Tell Overture.https://music.youtube.com/watch?v=sHQ1Date2v0&si=AXQgrbUq-eOj3529Winwood/Capaldi. 1970. Freedom Rider https://music.youtube.com/watch?v=Qsm1j_dDNtE&si=wd9r8LyeNJY5NGI5

References Peer J. 2018 Nov 23;6:e6021Front Neurol.2022 Apr11;13:804851.Davis, G.Rev. 1960 Death Don't Have no Mercy. Grateful Dead . Live Dead. lp.https://music.youtube.com/watch?v=-9IVP8pCN5U&si=J6Do1-FhfxD8ZzZ-Biber, HI. 1676 The Rosary Sonatas.https://music.youtube.com/watch?v=Z0ypvC5LN6s&si=lBp9iqqe3iEqJlNo

One in four adults is walking around with fatty liver, and most have no idea how much it can affect their energy, digestion, and long-term health. Now, when you combine fatty liver disease with losing your gallbladder, the very organ that helps break down fats, you've got a whole new set of challenges to navigate.Suddenly, your body has to relearn how to handle fats, which can make things feel even more complicated. Living with fatty liver with no gallbladder can feel frustrating, but the good news is you have more control than you think. That's why we're so glad to chat on IG Live with Lisa Winbourn, a Functional Nutritionist with a Bachelor of Science in Biochemistry. During this Live, we're going to discuss why it's hard to lose weight with fatty liver disease and no gallbladder, tips to improve digestion, why protein is so important, and so much more. Learn more about Lisa's services: https://linktr.ee/lisahealthjoyGet tested for BPA, phthalates, parabens, and other hormone-disrupting chemicals with Million Marker's Test Kit: https://www.millionmarker.com/

ReferencesNeuromolecular Med . 2024 Jun 1;26(1):22International Journal of Biological Macromolecules2020, Volume 163, 15 November Pages 1599-1617Nature. 2024 Mar 20;627(8005):865–872.Waters./Gilmour/Mason/Wright.1973. Time DSotM Pink Floydhttps://music.youtube.com/watch?v=yl-Ms_ek-kE&si=ay8gE7dkCOfBNjI4McCartney, P.1 970. Maybe I'm Amazedhttps://music.youtube.com/watch?v=slF3EBxZE6A&si=tIGuzL65_9Qr8UkaSimon, P.1966. Flowers Never Bend. PSR&T Simon and Garfunklehttps://music.youtube.com/watch?v=41XVWUL9VTE&si=HeFoIjpZ15MoT5r3Wilson/Love. 1966.. Good Vibrations. Beach Boyshttps://music.youtube.com/watch?v=oMfjgQ8ptrE&si=dZ4S6OkeNehhrzX8Beethoven LV 1807. Triple Concerto C Major. Op. 56https://music.youtube.com/watch?v=pkXGtE8_cig&si=NK4uP41aG2HoQmdn

mRNA vaccines are not supposed to contain DNA. But Dr. Jessica Rose says a new study tested “32 vials of Pfizer and Moderna COVID products that included 16 unique lots… We did not only find DNA, we found it in ALL lots tested and most importantly, the DNA levels were all above pre-designated EMA thresholds of 10 ng/dose.” “We measured the amount of DNA in the vials using 2 methods… (qPCR and fluorometry),” she continues. “It was submitted as evidence on the congressional record by the honorable Senator Ron Johnson.” JP Sears is a comedian, author, and YouTuber known for his satirical take on politics, fitness, and faith. He hosts Awaken with JP on Rumble and YouTube. Follow at https://x.com/AwakenWithJP Dr. Jessica Rose is a Canadian researcher with a Bachelor's in Applied Mathematics and a Master's in Immunology from Memorial University of Newfoundland. She holds a PhD in Computational Biology from Bar Ilan University and completed postdoctoral research in Molecular Biology and Biochemistry. Find her at https://jessicasuniverse.com and follow at https://x.com/JesslovesMJK 「 SUPPORT OUR SPONSORS 」 Find out more about the brands that make this show possible and get special discounts on Dr. Drew's favorite products at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/sponsors⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠• FATTY15 – The future of essential fatty acids is here! Strengthen your cells against age-related breakdown with Fatty15. Get 15% off a 90-day Starter Kit Subscription at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/fatty15⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • PALEOVALLEY - "Paleovalley has a wide variety of extraordinary products that are both healthful and delicious,” says Dr. Drew. "I am a huge fan of this brand and know you'll love it too!” Get 15% off your first order at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/paleovalley⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • VSHREDMD – Formulated by Dr. Drew: The Science of Cellular Health + World-Class Training Programs, Premium Content, and 1-1 Training with Certified V Shred Coaches! More at https://drdrew.com/vshredmd • THE WELLNESS COMPANY - Counteract harmful spike proteins with TWC's Signature Series Spike Support Formula containing nattokinase and selenium. Learn more about TWC's supplements at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twc.health/drew⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 「 MEDICAL NOTE 」 Portions of this program may examine countervailing views on important medical issues. Always consult your physician before making any decisions about your health. 「 ABOUT THE SHOW 」 Ask Dr. Drew is produced by Kaleb Nation (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://kalebnation.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠) and Susan Pinsky (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/firstladyoflov⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠e⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠). This show is for entertainment and/or informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment. Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Kristen Lynch is a Professor and Chair of Biochemistry and Biophysics at the University of Pennsylvania. Kristen's research focuses on alternative splicing. Her lab is investigating how cells decide when to use an entire portion of the DNA instruction manual versus when to exclude parts of the instructions that are not useful or would be harmful. In particular, Kristen is interested in alternative splicing in the immune system and what happens when cells are faced with an immune challenge. When she's not at work, Kristen loves being outdoors. She spends her free time kayaking, paddle boarding, biking, hiking, and doing yoga. She received her B.A. in biochemistry and her Ph.D. in biochemistry from Harvard University. Afterwards, Kristen pursued postdoctoral training at the University of California, San Francisco. She served on the faculty at the University of Texas Southwestern Medical Center prior to joining the faculty at the University of Pennsylvania in 2009. Kristen is the recipient of many awards and honors for her work, including a National Science Foundation CAREER Award. She joined us for an interview to talk about her experiences in life and science.

ReferencesFront Nutr. 2020 Jan 31;7:3.Nature .2024 Mar;627(8005):865-872Brain, Behavior, and Immunity .2024 116, February: 140-149Guerra, DJ. 2025. Unpublished Lectures.Lennon/McCartney. 1969. Let it Behttps://music.youtube.com/watch?v=QDYfEBY9NM4&si=URNgYVOl74n7IkNGTchaikovsky., PI. 1880. . Capriccio Italienhttps://music.youtube.com/watch?v=EhSb37hIryY&si=-2N4t8u2YBs9L6DT

ReferencesJACC 2017;69:1952-1967FEBS Letters1998. Volume 430, Issue 3, 3 July Pages 154-157Nature. 2024 Mar 20;627(8005):865–872.Molecular Neurobiology (2020) 57:5167–5176HHaydn , M. 1766 HobXXII 3 Cäcilienmesse Missa Cellensis in honorem Beatissimae Virginis Mariae in C majorhttps://youtu.be/wmvJlbakt-sHarrison, G. 1968. While My Guitar Gently Weeps White Album Beatleshttps://music.youtube.com/watch?v=YFDg-pgE0Hk&si=8KuffJ40UDIbtSs8Dylan, B.1962. Don't Think Twice Its Alrighthttps://music.youtube.com/watch?v=1iHhWh9FtsQ&si=Eex0R4pbFkrL-Jtn

ReferencesGuerra, DJ. 2025. Unpublished Lectures Trends Pharmacol Sci. 2009 Mar 9;30(4):174–181Molecular Neurobiology (2020) 57:5167–5176Stewart, S.. 1969 Everyday Peoplehttps://music.youtube.com/watch?v=YUUhDoCx8zc&si=HwMawlaaswvtMYHpLennon/McCartney. 1965. Girl. Beatles Rubber Soul.https://music.youtube.com/watch?v=-8l3ntDR_lI&si=AW3pAelz8CfJHGbyBetts, D. 1973. Ramblin Man. Allman Brothershttps://music.youtube.com/watch?v=A-bSe0i69yA&si=kVH2vGhBAKT2ENDR

Langlebigkeit ist zum Trendbegriff geworden. Doch die Wissenschaft versteht etwas völlig anderes unter dem Begriff "Longevity": Den Forschenden geht es nicht um Faltenfreiheit, einen schönen Körper und feste Zähne, sondern darum die gesunde Lebenszeit zu verlängern. Wie realistisch ist das? Ein Podcast von Caro Matzko. Credits: Autorin/Sprecherin: Caro Matzko Technik: Seed Redaktion: Yvonne Maier Unsere GesprächspartnerInnen: Prof. Christian Haass, German Center for Neurodegenerative Diseases (DZNE) Bzw. Biomedical Center Munich (BMC), Biochemistry an der Ludwig-Maximilians University Munich Prof. Dr. Magdalena Götz , Head of Stem Cell Center Department am Helmholtz Munich Prof. Dr. Annette Peters, Direktorin des Instituts für Epidemiologie des Helmholtz Zentrums München und Leiterin der NAKO Gesundheitsstudie Zum Weiterlesen und Quellen: Peter Attia: Outlive - The Science and Art of Longevity Die neuen Alzheimer Präparate https://www.pharmazeutische-zeitung.de/zweiter-alzheimer-antikoerper-kommt-im-zweiten-anlauf-157764/ WIRED-Interview: Bryan Johnson is going to die https://www.youtube.com/watch?v=CSFxtMviVqU&list=PLibNZv5Zd0dwEYACYgy9JjOgRxAwl-aHd&index=1 Zum Weiterhören: Ersatzteile für den Körper: Wie sicher sind Medizinprodukte? Hüftgelenk, Schrittmacher, Herzklappe: hier macht die Forschung große Fortschritte. Allerdings werden diese Produkte nicht immer so gut überwacht, wie es nötig wäre. Eine neue "Medizinprodukte-Verordnung" der EU soll das ändern. Aber ob sie die Situation verbessert, darüber wird zur Zeit heftig diskutiert. Ein Podcast von Hellmuth Nordwig. https://www.ardaudiothek.de/episode/urn:ard:episode:a92b7cdc7d85ed29/ Wir empfehlen: In dem Podcast Synapsen sprechen Korinna Hennig und Beke Schulmann mit Journalistinnen und Journalisten, die aktuelle Fragen aus der Gesundheitsforschung recherchiert haben. In der Folge "Koffein, Gesundheit, Klima: Die Zukunft des Kaffees" geht es zum Beispiel darum, ob Kaffee tatsächlich ungesund ist - oder ob er sogar vor Bluthochdruck, Herzkrankheiten und Krebs schützen kann. Außerdem erfahrt ihr, weshalb Kaffee manchen den Schlaf raubt, während andere völlig ungestört weiterschlummern. https://www.ardaudiothek.de/episode/urn:ard:episode:02b3cd7e9b0925cd/ "Synapsen - Gesundheit und Wissenschaft" - den Podcast findet ihr in der ARD Audiothek und überall, wo es Podcasts gibt. https://www.ardaudiothek.de/episode/urn:ard:episode:02b3cd7e9b0925cd/ Wir freuen uns, von Euch zu hören: WhatsApp https://wa.me/491746744240 oder iq@br.de Falls Euch der IQ-Podcast gefällt, freuen wir uns über eine gute Bewertung, einen freundlichen Kommentar und ein Abo. Und wenn Ihr unseren Podcast unterstützen wollt, empfehlt uns gerne weiter! IQ verpasst? Hier könnt ihr die letzten Folgen hören: https://1.ard.de/IQWissenschaft

Episode 062 | Bonnie Hodge, MD is a board certified dermatologist originally from Meridian, Mississippi. She specializes in skin cancer detection and treatment, management of psoriasis, acne, rosacea, atopic dermatitis, other common inflammatory conditions, and more complex conditions such as autoimmune and bullous dermatoses, pigmentation disorders, vitiligo, and prurigo nodularis.As a recent residency graduate, she has undergone extensive training in cutting-edge, evidence-based treatment strategies. She worked under several world-renowned experts in psoriasis, melanoma detection, alopecia, and pigmentary disorders.Dr. Hodge caught my eye through her rising, homegrown stardom on social media. As of the publication of this episode, she has amassed over 54K followers on TikTok! Her story is a great example of what can happen when you have the courage to leverage your expertise by consistently putting yourself in front of a camera and into the algorithm. Given the amount of misinformation our patients are routinely exposed to, the more board certified dermatologists who are willing to do this in an engaging, educational, and entertaining way, the better! Dr. Hodge graduated with a degree in Biochemistry from Mississippi State University. She received an MD from the University of Mississippi Medical Center School of Medicine and completed her dermatology residency at The University of Alabama, Birmingham.Outside the office, you'll find her enjoying life with her husband, Sonny, a sports medicine physician, and their son, Walker, alongside their canine companion named, Sipsey.This episode was recorded on May 27th, 2025.Connect with and learn from Dr. HodgeDr. Hodge on TikTokDr. Hodge on IGDr. Hodge at Haley DermatologyMore from Dr. Lewellis and Above & Beyond DermatologyNeed a dermatologist? Fill out this short interest form, text or call me at 715-391-9774, or email me at drlewellis@aboveandbeyondderm.com if you'd like to have a no obligation discovery call. I offer in-office visits, house calls, and virtual care in Wisconsin and virtual care in Illinois, Nebraska, and Colorado.Have an idea for a guest or want to be on the show yourself? Send me a text or email, and we'll see if it's a good fit.Above & Beyond DermatologyNutrafol -- special pricing and physician exclusive productsNeoGenesis -- my favorite source of stem cell released molecules for skin/hairSilagen.biz -- physician dispensed scar refinement products delivered to your door (use practice code 1206240832P)NewsletterLinkedInFacebookDr. Lewellis on InstagramAbove & Beyond Dermatology on InstagramYouTubeTikTokTwitter/XChange Your Mind, Change Your LifeSoMeDocs (Doctors on Social Media)Pippa!

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden and Dr. Nichola Conlon delve into the complexities of aging, focusing on the important role of NAD (Nicotinamide Adenine Dinucleotide) in cellular health and longevity. They discuss how NAD levels decline with age, the implications of this decline, and innovative strategies to boost NAD levels effectively. The conversation also touches on the limitations of IV NAD therapy, the importance of addressing inflammation, and the scientific validation behind the Nuchido Time product. Dr. Conlon shares insights into future research directions and the impact of customer feedback on product development, emphasizing the need for a comprehensive approach to enhancing cellular health.   For Audience ·       Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ !  ·       www.nuchido.com/GLADDEN or simply use code GL20 at Checkout on www.nuchido.com for 20% off your first order!   Takeaways ·       NAD is crucial for driving cellular repair processes. ·       The decline of NAD is linked to aging and inflammation. ·       Addressing root causes of NAD decline is essential. ·       IV NAD therapy may not effectively increase intracellular NAD levels. ·       NAD recycling is a complex process influenced by various enzymes. ·       Chronic inflammation can significantly deplete NAD supplies. ·       Nuchido Time aims to optimize NAD levels through a comprehensive approach. ·       Customer feedback drives ongoing research and product development. ·       NAD levels fluctuate throughout the day, impacting circadian rhythms. ·       Future studies will explore NAD's effects on sleep and skin quality.   Chapters 00:00 Introduction and Background 04:00 The Importance of NAD in Aging 07:45 Understanding NAD Depletion and Its Causes 12:47 The Role of CD38 in NAD Dynamics 16:42 Innovative Approaches to NAD Supplementation 21:26 Comparing NAD IVs and Oral Supplements 25:12 Enhancing NAD with Ozone Therapy 28:04 Product Development and Optimization 33:47 Future Research Directions and Applications   To learn more about Dr. Nichola Conlon: Website: www.nuchido.com Email: care@nuchido.com Social media: @nuchido @drnicholaconlon Got a question for Dr. Gladden? Submit it using the link below and it might be answered in our next Q&A episode! https://form.typeform.com/to/tIyzUai7? Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw    

ReferencesInt J Mol Sci. 2022 Jul 8;23(14):7592. Exp Mol Med . 2024 Apr;56(4):946-958.Front Endocrinol (Lausanne). 2020 Jul 29;11:483.Nature Structural & Molecular Biology 2025 .32, pages431–440 Kath, T. 1970.Memories of Love Chicago II https://music.youtube.com/watch?v=GFjWeUnt6nY&si=mHjfAhTlwVyXE0ZMSchubert, F. 1829. Standchen 4 D 957https://music.youtube.com/watch?v=pJf-XXTBEqs&si=2fMoDFFsHz_i1H0GSimon, P. 1966. Scarborough Fare.https://music.youtube.com/watch?v=-Jj4s9I-53g&si=OA7lBVGkiPXlPpoJLennon/McCartney. 1966. Rainhttps://music.youtube.com/watch?v=nrEgtOeJGzQ&si=D1lQwT-_ck2pBD_X

ReferencesInt J Mol Sci. 2022 Jul 8;23(14):7592. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology2012. Volume 163, Issue 1, September. Pages 26-36Molecular Neurobiology 2019. v.56, pages 5436–5455, Lennon/McCartney. 1970.. One After 909. From Let It Be lphttps://music.youtube.com/watch?v=t8UeWjynWvE&si=aUHXUFiv315uNWWkPetty/Lynne/Campbell. 1989. Running Down a Dreamhttps://music.youtube.com/watch?v=8MUg8mpnhvQ&si=HgcU5gWoA753gOmCBruce/Brown. .1968. Deserted Cities of the Heart. Live Cream II.https://music.youtube.com/watch?v=kBHh2d4zhV8&si=22Cdzk9XrRK_AUakDavies, R. 1979 Low Budgethttps://music.youtube.com/watch?v=FbCZJbPcJFI&si=EEjUj-QobN04yzOA

In this episode of The Birth Lounge Podcast, HeHe sits down with clinical pharmacist Dr. Michaela Wachal to unpack the controversy surrounding Tylenol (acetaminophen) use in pregnancy and its potential links to autism and other neurodevelopmental concerns. Together, they dive into what the research actually says (and doesn't say), why transparency and informed consent are so important, and how to navigate decisions around medications in pregnancy with confidence. Dr. Wachal also highlights the bigger picture, like how genetics, environmental toxins, and even maternal stress can play a role in outcomes, and why caring for yourself is just as critical as any prescription. This conversation is packed with nuance, evidence, and practical takeaways to help you feel informed, empowered, and ready to advocate for yourself as you make decisions about your pregnancy care. 00:00 Introduction and Media Misrepresentation 01:05 Personal Story and Birth Lounge App 02:16 Empowering Prenatal Conversations 05:26 Emergency Use Authorization Episode 07:34 Interview with Dr. Michaela Wachal 09:14 Medication Safety in Pregnancy 12:37 Pharmaceutical Industry Failures 15:20 Personal Journey and Advocacy 18:55 Questioning Medical Norms 21:15 Tylenol and Toxins 23:34 Aluminum in Vaccines 27:32 The Importance of Transparency 37:05 Advocating for Education and Understanding 37:51 The Power of Asking Questions 40:21 Nesting and Preparing for Baby 43:17 Managing Fevers During Pregnancy 52:01 Environmental Toxins and Health 01:00:41 Therapies and Support for Children on the Spectrum 01:09:27 Final Thoughts and Encouragement   Guest Bio: Michaela Wachal, PharmD, CSP, is a clinical pharmacist, Certified Specialty Pharmacist, and Clinical Accreditation Manager with nearly a decade of experience in specialty pharmacy. She holds a Doctor of Pharmacy degree from the University of Nebraska Medical Center and a Bachelor of Science in Biochemistry from Doane University. Throughout her career, she's specialized in complex conditions including oncology, fertility, endocrinology, immunology, mental health, and inflammatory diseases—always with a passion for improving patient care, optimizing healthcare systems, and empowering women in medicine. Michaela is also a mom of three, including one child with autism, ADHD, and anxiety, which ignited her deep interest in neurodiversity, integrative health, and individualized medicine. After navigating her own family's challenges, she began researching functional and evidence-based approaches to support children and families living with complex needs. Online, Michaela shares insights from scientific studies on autism, ADHD, vaccines, autoimmune conditions, toxins, and more, always with a focus on helping parents make informed, evidence-based choices. Her work blends professional expertise with personal passion, making her a trusted voice in both the pharmacy world and the parenting community.   INSTAGRAM: Connect with HeHe on IG  Connect with Dr. Wachal on IG    BIRTH EDUCATION: Join The Birth Lounge here for judgment-free childbirth education that prepares you for an informed birth and how to confidently navigate hospital policy to have a trauma-free labor experience!   Download The Birth Lounge App for birth & postpartum prep delivered straight to your phone!   RESEARCH MENTIONED: 2021 there's a call for action published supported by 91 scientists, clinicians and public health professionals across the globe recommended that pregnant women should be cautioned at the beginning of pregnancy to forego APAP unless it is medically indicated and to minimize the exposure by using the lowest effective dose for shortest possible time https://pubmed.ncbi.nlm.nih.gov/34556849/   Boston Birth cohort published in 2020 looked at acetaminophen metabolites in cord blood samples collected at birth and unchanged acetaminophen levels were detected in all cord plasma samples and acetaminophen burden was associated with higher odds of ADHD  and ASD daignosis there was a 2.3 to 3.5 increased risk for ADHD and 1.6 to 4.1 increased risk for ASD https://pubmed.ncbi.nlm.nih.gov/31664451/   Recently in August Harvard did an analysis using the Navigation Guide methodology that supports evidence consistent with an association between acetaminophen exposure during pregnancy and increased incidence of Neurodevelopmental disorders. This included 46 studies with 27 reporting positive associations with the higher quality studies more likely to show positive correlations https://ehjournal.biomedcentral.com/articles/10.1186/s12940-025-01208-0   Nurses Health Study https://pubmed.ncbi.nlm.nih.gov/30923825/ Spanish birth cohort where acetaminophen exposure was associated with more hyperactivity/impulsivity https://pubmed.ncbi.nlm.nih.gov/27353198/   In 2018 there was a review that showed that 9 prospective cohort studies that all suggested an association between prenatal APAP exposure and neurodevelopmental outcomes - ADHD, ASD or lower IQ and longer duration was associated with increased risk https://pubmed.ncbi.nlm.nih.gov/29341895/   2022 a prospective cohort study in Pennsylvania looked at 2,423 moms using data and children who were exposed to APAP during pregnancy scored higher for child behaviors, sleep problems and attention problems  https://pubmed.ncbi.nlm.nih.gov/36170224/ Keywords: Tylenol pregnancy, acetaminophen pregnancy, Tylenol autism risk, pregnancy medication safety, prenatal care, evidence-based pregnancy, maternal health, neurodevelopment, pregnancy decision making, informed consent pregnancy, pregnancy medications, Dr. Michaela Wachal, Birth Lounge podcast, pregnancy self-care, pregnancy toxins

Dr. Nicole Paulk is the CEO, Founder, and President of Siren Biotechnology and has dedicated her career to advancing the field of gene therapy. With nearly two decades of expertise, Nicole has been at the forefront of developing cutting-edge advances to propel the field of gene therapy forward for a wide range of diseases. Nicole has held various leadership positions in academia and industry and most notably was an Assistant Professor of AAV Gene Therapy in the UCSF Department of Biochemistry & Biophysics before leaving to found Siren. Nicole has a B.S. in Medical Microbiology, a Ph.D. in Viral Gene Therapy and Regenerative Medicine from OHSU and completed her Postdoctoral Fellowship and Instructorship in Human Gene Therapy at Stanford University prior to starting her lab at UCSF. Nicole is a pioneer in the development of next-generation AAV platforms for gene repair, gene transfer and gene editing, directed evolution for novel engineered capsid evolution, and comparative multi-omic approaches to interrogate translational AAV biology.

ReferencesExp Mol Med. 2024 Apr 1;56(4):946–958.UBMB Life. 2010 May;62(5):347–356.Guerra, DJ. 2025. Unpublished LecturesCell Mol Immunol 2006 Feb;3(1):11-9J Neuroinflammation. 2019 Feb 25;16:48.Jones, S. 1948 . Ghost Riders in the Sky Johnny Cashhttps://music.youtube.com/watch?v=rRowehhX9I4&si=jco59v9Hi_BGWdy4Strauss, R. 1915. An Alpine Symphony OP.64https://music.youtube.com/watch?v=O8-M0ULcAy8&si=tXwy1CPpkQtYXose

This episode covers:In this episode, we discuss how trauma is stored in the body, the difference between stress and trauma, and practical somatic tools to start healing, and so much more.Dr. Aimie Apigian, MD, MS, MPH, is a double Board-Certified Physician, boarded in both Preventive and Addiction Medicine with a Masters in Biochemistry and a Masters in Public Health. She is a leader, speaker and founder of Trauma Healing Accelerated, LLC where she not only continues to lead individuals in their own healing journey but trains professionals around the world to do the same.After a few years in a general surgery residency in Portland, OR, Dr. Aimie decided to forge her career path as a Trauma, Attachment and Addiction Medicine Physician.  She believes the healing journey can be accelerated by bringing in the biology piece to trauma and applying strategic tools to address the chronic effects of trauma in one's body.  Having both parented children with effects from attachment and trauma issues and then having her own health challenges from chronic stress and traumas, she is intensely invested on finding what actually works practically and how to restore the body to its highest potential for health optimizing the biology.Links mentioned during this episode:Dr. Aimie's Book, The Biology of Trauma: https://book.biologyoftrauma.com/landing-pageFree Initial Consultation with Dr. Megan: https://p.bttr.to/3a9lfYkLyons' Share Instagram: www.instagram.com/thelyonsshareJoin Megan's Newsletter: www.thelyonsshare.org/newsletter

Send us a textHow nutrition and medications impact mitochondrial health.Wide release date: October 1, 2025.Episode Summary: Dr. Chris Masterjohn talks about the intricate relationships between nutrition, prescription drugs, and mitochondrial health, discussing how molecules like acetaminophen and SSRIs affect the body beyond their intended purposes, particularly impacting inflammation and energy metabolism. The discussion gets into the broader implications of serotonin outside the brain, the side effects of commonly used medications, and the importance of personalized nutritional strategies to optimize mitochondrial function.About the guest: Chris Masterjohn, PhD holds a doctorate in nutritional sciences and is a co-founder of Mitome, a company focused on mitochondrial testing to optimize cellular energy production.Discussion Points:Acetaminophen & Inflammation: Acetaminophen (Tylenol) may contribute to chronic low-grade inflammation by blocking both the initiation and resolution of inflammation, potentially linked to health issues like autism when used during pregnancy.Serotonin's Role Beyond the Brain: Approximately 95% of serotonin is found in the gut, regulating motility, with SSRIs causing side effects like nausea due to increased extracellular serotonin.SSRIs & Mitochondrial Function: SSRIs disrupt serotonin uptake into cells, reducing mitochondrial melatonin production, which impairs the body's ability to handle hypoxic stress and produce ATP efficiently.Statins & Mitochondrial Impact: Statins, used to lower cholesterol, inhibit the mevalonate pathway, affecting not just cholesterol but also CoQ10 and vitamin K2, crucial for mitochondrial function, potentially leading to side effects like myopathy.Mitochondrial Testing with Mitome: Masterjohn's company, Mitome, uses cheek swab tests to measure mitochondrial respiratory chain activity, providing personalized dietary and lifestyle recommendations to optimize cellular energy production.Nutrition & Mental Health: Masterjohn shares his personal experience of severe mental health issues on a vegan diet, which improved dramatically with a nutrient-dense diet rich in organ meats, highlighting individual nutritional needs.Energy Metabolism's Universal Role: Mitochondrial ATP production governs everything from daily energy levels to long-term health, with personalized testing helping identify and address specific bottlenecks.*Not medical advice.Support the showAffiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount. For all the ways you can support my efforts

Synopsis: When biotech meets bold partnerships, new models of innovation emerge. In this episode of the Biotech 2050 Podcast, host Rahul Chaturvedi welcomes Paul Biondi, Managing Partner at Flagship Pioneering, and Uli Stilz, Vice President, R&D External Innovation Partners at Novo Nordisk, to explore the power of co-creation. Together, they unpack how Flagship's pioneering medicines model and Novo's Bio Innovation Hub intersect to accelerate breakthroughs in obesity, diabetes, and cardiometabolic diseases. They share lessons on building trust, navigating crises, and structuring alliances that go beyond transactions into enduring innovation ecosystems. From human disease atlases to new frameworks for agile collaboration, this episode offers a rare behind-the-scenes look at how pharma and biotech can partner differently—turning complexity into transformative therapies. Biography: Paul Biondi is a Managing Partner at Flagship Pioneering, leading Flagship's product and partnering capabilities, including Pioneering Medicines, Partnering, and Pipeline and Product Innovation. In this role, Paul oversees Pioneering Medicines, Flagship's in-house drug discovery and development unit, as well as therapeutic partnering and business development efforts for the Flagship ecosystem, including driving broad institution-wide Innovation Supply Chain partnerships with biopharma companies to jointly conceive and create innovative products. Paul also works with Flagship company CEOs and their teams to achieve the best attainable value for each company, guiding them in their pipeline strategy, product concepts, R&D execution, and partnering approach. He serves on the boards of Flagship-founded companies, including Tessera Technologies (NASDAQ: TSRA) and Valo Health. Paul Biondi is Managing Partner at Flagship Pioneering, joining after 17 years at Bristol-Myers Squibb (BMS), where he served as SVP of Strategy & Business Development and held leadership roles in R&D. He previously spent nine years at Mercer Management Consulting. Paul earned his MBA from the Kellogg School of Management at Northwestern University and his B.A. from Dartmouth College. Uli Stilz is Corporate Vice President, R&D External Innovation Partners, External & Exploratory Innovation (E2I) at Novo Nordisk., based in Boston. He leads a global R&D team that builds creative partnerships with biotech, venture capital, academia, and research hospitals to co-create next-generation therapeutics in cardiometabolic and rare diseases. Building on the success of the Novo Nordisk Bio Innovation Hub, Uli and the E2I team drive an externally anchored portfolio of collaborations that stimulate global innovation ecosystems and advance Novo Nordisk's pipeline. Uli Stilz earned his Master's in Organic Chemistry from ETH Zürich and a Ph.D. in Biochemistry from the Max-Planck-Institute of Biochemistry in Martinsried, followed by postdoctoral research at Caltech. He began his industry career at Hoechst AG and later Sanofi, where he became Associate VP of the Innovation Unit in the Diabetes Division. Over two decades, he contributed to more than 60 preclinical and clinical drug candidates in cardiometabolic, immunology, and oncology. From 2012–2014, he served as President of the European Federation for Medicinal Chemistry. In 2014, Uli joined Novo Nordisk in Copenhagen and in 2019 moved to Boston to establish and lead the Bio Innovation Hub, now the External & Exploratory Innovation (E2I) organization. He also serves as Adjunct Professor at the University of Frankfurt, sits on editorial and scientific advisory boards, and holds board roles at the Kendall Square Association and Gensaic, while advising the aMoon Fund.

referencesExp Mol Med. 2024 Apr 1;56(4):946–958 J Cell Physiol.. 2024 May;239(5):e31230Guerra, DJ. 2025.Unpublished LecturesTownsend, P. 1971 Wont Get Fooled Again. From Who's Next The Whohttps://music.youtube.com/watch?v=Jtb10ZwbReY&si=jiRwoTM70ibkbAHdTownsend, P .1969 Pinball Wizard from Tommy lp.https://music.youtube.com/watch?v=3xZzGtDW2p4&si=7EROWKQO7DreWHHJAnderson, I. 1969. We Used to Know from Stand Up lp.Jethro Tull.https://music.youtube.com/watch?v=oGvux7w1Ea4&si=s8rzKSAvM4aQSahZMozart WA 1788. Symphony 41 in C Major K. 551https://music.youtube.com/watch?v=0VuSqLbFwXM&si=J4tvwnIBGUMbGlFL

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ReferencesNature Reviews Drug Discovery.2022. 21: 339–358 Academia Biology, 2025.vol. 2, no. 3, J Cellular Physiol.2024.Volume 239, Issue 5 May e31230.Guerra, Dj. 2025. Unpublished LecturesSeeger, B. 1971. Turn the Page.https://music.youtube.com/watch?v=t9G6Ec1DDlc&si=8ixyA8ESHPXyUBAgSeeger, B. 1975. Katmandu.https://music.youtube.com/watch?v=4s1-e88R3OU&si=yGktYIc_HqM0QZFVMiller, S. 1972. Space Cowboyhttps://music.youtube.com/watch?v=95dM-K5fSKQ&si=EBMjIdvh5oPxjR2wMozart, WA> 1780. Violin Concerto 5. https://music.youtube.com/watch?v=vudKSLyeWEg&si=7SwEEUkSt4eOwAvo

ReferencesCells. 2021 Jun 3;10(6):1382Mol Biol Rep. . 2023 Jan;50(1):777-788Open Access Library Journal .2017, Volume 4, e3492 J Interferon Cytokine Res. 2014 Aug 1;34(8):577–588International Immunopharmacology. 2020. Volume 80, March 06210Signal Transduction and Targeted Therapy 2021. 6, Article number: 402Lennon/McCartney. 1964. If I Fell .Hard Days Night lp. Beatleshttps://music.youtube.com/watch?v=F_80s6S_7Vw&si=6uePjPglrMjI_geCJoel, B. 1980. I Dont Want to Be Alone. Glass House, LPhttps://music.youtube.com/watch?v=vhn4mH3uA1A&si=dYT2W6BMDmMzmG1hTempchin, J. 1972. Peaceful Easy. Feeling. Eagleshttps://music.youtube.com/watch?v=QRMIgT3thFM&si=qSuX5m0F0r9K4UXwSchubert, F. 1827. Piano Trio in E flat. OP 100.https://music.youtube.com/watch?v=k_jknESj68E&si=_d19-CrGPKqOdJKo

Elizabeth Cronlund is joined by Marie Moy to confront some common narratives about Asian American and Pacific Islander populations. They take a look at some of the history of AAPI in the United States, and reflect on the ways that history informs where we find ourselves today. They also share some ways we can build coalitions and stand in solidarity so we are able to move forward together.Learn more about CCDA's AAPI Network at ccda.org/aapi. And make plans to join us at the CCDA Conference this November at ccda.org/conference.Marie Moy serves as the Director of Operations and is a member of the Restorative Practices training and implementation team at Erie County Restorative Justice Coalition (ECRJC). ECRJC's mission is to promote racial and social justice through Restorative Practices, providing training, coaching, consulting, and restorative responses, including Restorative Justice Conferencing in lieu of traditional punitive measures. Marie grew up in a small town in northern Indiana, where her parents owned a Chinese-American restaurant. As children, she and her sisters attended an independent Baptist church. Marie first learned of Christian Community Development while attending Renovation Church in Buffalo in 2010. She participated in CCDA's El Camino del Inmigrante in 2016 with approximately 70 others to bring attention to the plight of immigrants. Marie is a graduate of Northeastern Seminary at Roberts Wesleyan College in Rochester, NY, with an MA in Theology & Social Justice from Indiana University, Bloomington, with a BS in Biochemistry. Marie integrates her background in science and theology to bring just practices to the operations of organizations, and is particularly interested in creating spaces without traditional hierarchy that are inclusive and supportive of marginalized communities. As a second-generation Asian American, Marie is passionate about immigration reform in addition to her work with ECRJC to end mass incarceration and restore relationships and communities. Marie is married with two adult children and a small Cavalier King Charles/poodle mix named Chani. She is a member of the CCDA Board and Leadership Cohort 8, and the John R. Oishei Foundation Karen Lee Spalding Oishei Fellows for Leaders of Color. She is embarking on a sabbatical to spend time with God and an exploration of embodied restorative practices after a long season in nonprofit work.Based in Orlando, FL, Elizabeth Cronlund is the Partnership Development Manager with UNDIVDED, an organization that is activating communities for racial healing and justice. She has more than 15 years of experience in congregational ministry as a Christian Community Developer. Within CCDA, she helps lead the AAPI Network and is a contributing writer for CCDA's Education Equity Handbook. Elizabeth is a Certified Nonprofit Professional (CNP) and attends Northern Seminary.Connect with CCDA on Instagram, Twitter, Facebook, and LinkedIn. Follow CCDA on YouTube.

In this episode we discuss:   Whether Dr Ray Peat had it all wrong   Potential reasons why someone may be bloating from carbs How to add carbs back in following restrictive diet   Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/ Theresa's Instagram: https://www.instagram.com/livingrootswellness/   Timestamps: 0:00 – intro  0:32 – Justine Stenger's claim that Dr Ray Peat had it all wrong  6:15 – did Ray Peat ignore physics, structured water, and light?  11:41 – carbs vs fat: which fuel produces more ROS?  16:50 – Justine Stenger's claim that carbs act as a crutch for a damaged metabolism, and restoring redox is the solution  21:58 – carbs vs fat: which fuel produces more ATP?  25:27 – conflicting health information on social media and why the “Ray Peat diet” doesn't work  31:55 – common challenges with implementing Ray Peat's work  34:09 – Justine Stenger's mischaracterization of Ray Peat's work as a “dietary roadmap for people with a broken metabolism”  41:20 – why you shouldn't outsource critical thinking to social media influencers or AI  45:17 – Ray Peat's generosity with freely sharing advice and information  46:21 – improvements on a bioenergetic approach without extreme restriction  47:31 – why you may experience bloating from carbs and what to do about it  54:52 – what to do about gut dysbiosis and biofilms  56:56 – how to restore gut health and digestion when transitioning away from keto