Podcasts about Biochemistry

Episode Highlights With KatieWhy the traditional biochemical model of the body is incomplete...and why the body is electric firstThe shocking amount of energy your body generates each day (about your own body weight in ATP!)Why 90–95% of chronic diseases have mitochondrial dysfunction at the rootHow your mitochondria act not just as powerhouses but as quantum batteries, antennas, and information hubsThe surprising sources of electrons that create cellular voltage...including sunlight, melanin, movement, structured water, and the earth itselfHow infrared light charges your “quantum battery,” while artificial blue light breaks it downWhy hydration with minerals is essential for building cellular charge (and why plain water can ake things worse)The nutrients mitochondria require to function: phospholipids, healthy fats, CoQ10, copper, B-vitamins, carnitine, creatine, and moreWhat redox really means and why redox balance must come before detoxHow a collapse in redox leads to the Cell Danger Response, chronic symptoms, and stalled healingThe many ways modern life drains voltage: lack of sunlight, EMFs, stress, toxins, blue light, poor sleep, dehydration, and circadian disruptionSimple daily strategies to restore voltage...starting with light, minerals, movement, grounding, and sleepHow tools like red/near-infrared light, PEMF, BioCharger, sauna, cold therapy, Juvent, and vibration plates support mitochondrial energyResources MentionedRed light therapyPEMF matBioChargerSaunasPower Plate vibration plateCold plungeJuventJustine ClassThe Body ElectricDr courtney hunt insta and websiteYour spark is light classMineral podcast seriesWater structure pitcher affiliate linkRebounder on amazon

ReferencesScience. 2013 Nov 8;342(6159):727–730.Biomedicine & Pharmacotherapy 2025. Volume 183, February Guerra, DJ.2026. Unpublished LecturesBeethoven, LV. 1812. Symphony 8 in F Major. Op93https://music.youtube.com/watch?v=FMEL6z9Qir8&si=ycnEA9nSZrLqkKca

ReferencesCold Spring Harb Symp Quant Biol 2011. 76:31-38. Scientific Reports 2024 volume 14, Article number: 1773 Guerra, DJ.2026. Unpublished Lectures.Stevens, C. 1970. Father and Sonhttps://open.spotify.com/track/476V2d6iA2tWXgQboKmTtA?si=c4c5d1b6a34043e1Mydland, B. 1989. I will Carry You Home. Grateful Dead.https://open.spotify.com/track/1Q3AmIjEbPYemA6UkjUUu0?si=b3b29503e29c4b5c

Bosma arhinia microphthalmia syndrome (BAMS) is a rare genetic disorder resulting in babies born without a nose, along with eye and reproductive anomalies. Our guests today investigated the developmental basis of this distinct defect using induced pluripotent stem cells (iPSCs) derived from patients with BAMS. They assessed the differentiation potential of BAMS patient-derived iPSCs into cranial placode cells, a group of progenitor cells that contribute to the formation of the nasal epithelium. This allowed them to study the behavior of the nasal epithelial cells during early development. Their work uncovered cellular mechanisms underlying BAMS and provided new insights into the developmental processes that shape the human nose. GuestsShifeng Xue is an Assistant Professor in the Department of Biological Sciences at the National University of Singapore (NUS). She received her Ph.D. in developmental biology from the University of California, San Francisco, where she trained with Maria Barna, and then completed her postdoctoral research at the Institute of Molecular and Cell Biology, A*STAR, Singapore. She is the recipient of the 2018 Young Scientist Award of the Singapore National Academy of Science.  Vanitha Venkoba Rao worked as a Research Fellow at NUS from 2020 to 2025. She earned her Ph.D. in Biochemistry and Molecular Biology from NUS and subsequently held research positions at inStem and Pandorum Technologies in India, before joining the Xue lab.HostJanet Rossant, Editor-in-Chief, Stem Cell Reports Supporting DocumentCranial placode differentiation defect in individuals born without a nose, Stem Cell Reports, 2026About Stem Cell ReportsStem Cell Reports is the open access, peer-reviewed journal of the International Society for Stem Cell Research (ISSCR) for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians. X: @StemCellReportsAbout ISSCRAcross more than 80 countries, the International Society for Stem Cell Research (@ISSCR) is the preeminent global, cross-disciplinary, science-based organization dedicated to advancing stem cell research and its translation to medicine.ISSCR StaffKeith Alm, Shuangshuang Du, Kym Kilbourne, Megan Koch, Jack Mosher, and Hunter Reed

ReferencesChemBioChem, 2018.v.: 19, Issue: 15, : 1657-1663, J Pineal Res. 2007 Nov;43(4):317-20Journal of Molecular Endocrinology (2019) 63, R93–R102Front Aging. 2023 Jul 3;4:1202152Guerra, DJ.2026.Unpublished Lectures Simon, P. 1966. Homeward Bound Simon& Garfunkelhttps://open.spotify.com/track/4Xl2PrS3DJqqSKXCo6Uhv9?si=bbec6ac10e7b4940McVie. 1971. Homeward Bound Fleetwood Machttps://open.spotify.com/track/5BYIir2GcICaFUWMFkUhyV?si=c769fae01a504f34Hayward, J. 1971 You Can Never Go Home. Moody Blueshttps://open.spotify.com/track/4qJCmI59iStWJJUatMEIEm?si=da6d023dbf304920

References Cell Death & Disease 2018. v. 9, Article number: 600CNS Neuroscience & Therapeutics 2009. 15:32–51Oncol Lett 2016 Aug;12(2):897-903.Cell Death Discovery  2025V 11, Article number: 489 Biomedicine & Pharmacotherapy2024 v. 172, March 116229Guerra, DJ. 2026. Unpublished Lectures.Lennon/McCartney.1968. I'm So Tired. White Album-Beatleshttps://open.spotify.com/track/2X9H5BokS1u5O46YpNYNsZ?si=bdcc11350bc24d90Dubin/Warren. 1935.Lullaby of Broadway -Doris Day.(1951).https://open.spotify.com/track/4hG3Xgm6H4ELBi8ESQoosr?si=b5a84bdc0be84dbc

For decades, the field focused on the plaques and tangles of misfolded proteins that show up in the brains of patients with Alzheimer's, Parkinson's and other disorders. The natural assumption was that if you could design a drug to clear out that gunk, you could save the brain. But so far, that bet hasn't paid off.Now, researchers are taking a big step back and asking whether the plaques aren't a culprit, but rather a clue pointing to something more fundamental going wrong in our brain cells as we age? Put another way, why do our brains get jammed up with these junk proteins in the first place?Today's guest, chemical engineer and geneticist Monther Abu-Remaileh, is one of the researchers working hard to answer that question. His research goes deep on a tiny cellular structure called the lysosome, little sacs filled with acid and enzymes that break down worn-out proteins and cellular debris. The lysosome is like a sustainable recycling center for a major city, managing waste streams, recycling raw materials, and coordinating with the rest of the cell to keep things running – and when it breaks down, the whole cell starts to fail. Among other accomplishments, Abu-Remaileh, a member of the Knight Initiative for Brain Resilience Steering Committee, has developed clever techniques for probing the lysosome that have put him at the frontier of a transformation in how we think about the lysosome, a transformation that could point the way to slow all manner of neurodegeneration – or even prevent it from happening in the first place.Learn MoreFrom humble beginnings to unlocking lysosomal secrets (ASBMB Today, 2026)‘You can literally lose who you are' (Stanford Report, 2025)Driver of neurodegenerative diseases revealed (Stanford Engineering, 2023)New atlas could help researchers studying neurological disease (Knight Initiative for Brain Resilience, 2026)Sifting through cellular recycling centers (Stanford Engineering, 2022)Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes(Science, 2017)CLN3 is required for the clearance of glycerophosphodiesters from lysosomes (Nature, 2022)The Batten disease gene product CLN5 is the lysosomal bis(monoacylglycero)phosphate synthase (Science, 2023)The Bis(monoacylglycero)-phosphate Hypothesis: From Lysosomal Function to Therapeutic Avenues (Annual Review of Biochemistry, 2024)PLA2G15 is a BMP hydrolase and its targeting ameliorates lysosomal disease (Nature, 2025)Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder(Cell, 2026)Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience.We want to hear from your neurons! Email us at at neuronspodcast@stanford.eduLearn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn. 

ReferencesInt J Mol Sci. 2022 Jul 29;23(15):8412Am Soc Clin Oncol Educ Book 2023. 43, e390876(2023)Volume 43Cells.2019 Sep; 8(9): 1047.Communications Biology2021 volume 4, Article number: 1270Guerra, DJ 2026. Unpublished LecturesPisendel , JG. 1735.. Violin Concerto in D major Jung1.7https://music.youtube.com/watch?v=m3ZcDvoxCpA&si=ZQhvMUOXtiYa4bbr

Today I'm joined with Liev Dalton to dive into Terrain Theory, Germ Theory, Natural Law, and honestly - the coming home to the remembrance of our own innate power to heal. Liev is an absolute wealth of knowledge and wisdom when it comes to terrain and understanding the deeper mechanics and biology of the human body. I was so excited to sit down with him and learn more about this field, as this is a more new field to me. I personally have studied health and wellness my whole life, and honestly, I learned SO much. This truly feels like the future of healing and medicine, and so I am so excited to share this episode with you all. He put words and science to back up the deeper energetic things I've been feeling for years.   Liev Dalton studied Biochemistry and Molecular Biology at Dalhousie University and was on track to become a dental surgeon before shifting into counselling psychology. He went on to open and run a successful therapy practice, working with wilderness therapy, EMDR, somatics, and nervous system regulation. Over time, he realized the model often kept people stuck in cycles of healing. Beyond formal education, Liev explored natural law, philosophy, and countless healing modalities. That path led him to the Terrain. His work now focuses on unlearning modern misconceptions and returning to simplicity. In doing so, this creates the conditions for clarity, resilience, and a deeper sense of well-being.  You can connect with him at www.Beyondterrain.com or instagram  @BeyondTerrain      Let's go deeper ✨    Subscribe here: https://www.youtube.com/channel/UCltzHzSg-W8Z2VxPNyyjX7Q/?sub_confirmation=1    Your Soul Blueprint: https://mailchi.mp/0fe31e348882/energy-blueprint-reading     Health Report: https://jasmineelise.gumroad.com/l/healthreport   Stay in the know & Receive updates & channeled messages: https://bit.ly/3rrzpyl   Let's Dive Deep

ReferencesOncotarget. 2017 Aug 22; 8(34):55967–55983.Front Pharmacol. 2022 Aug 11;13:940629Int. J. Mol. Sci. 2023, 24(19), 15030Guerra, DJ.2026. Unpublished LecturesLamm, R. 1969.25 or 6 to4 Chicagohttps://open.spotify.com/track/7GqIDx2QVGOpd4r1fZaUUW?si=967a6208fb644728

ReferencesCell Death Dis. 2021 Sep 13;12(9):847.Theranostics. 2020 Jul 9;10(18):8315–8342.Int.J. Mol. Sci. 2024, 25(21), 11469Guerra, DJ.2026.Unpublished Lectures.Capaldi/Winwood.1967. 40,000 Headmen. Traffichttps://open.spotify.com/track/5YAPlTgnNDKmagJBccKaeR?si=e04f0dab65df46f4Leach, Donovan. Var by Duane Allman. 1967/1971. . Mountain Jam Live Allman Brothers. https://music.youtube.com/watch?v=5-3L1MFBKZY&si=_59ldBfIMhcfrtCC

Today, on Karl and Crew, we kicked off our weekly theme, “Chivalry.” Dr. Fazale Rana, also known as Dr. Fuz, joined us to discuss how biochemistry points to God’s design, explaining that discoveries in DNA and the unique human capacities for altruism, empathy, and chivalry reflect what it means to be made in the image of God. Dr. Fuz is the President, CEO, and Senior Scholar at Reasons to Believe, a non-profit that focuses on revealing God in science. Next, Seth Troutt joined us to talk about authentic masculinity, explaining how men can reject counterfeits such as passivity and toxic masculinity by pursuing godly character, Christlike responsibility, and biblical chivalry. Seth is the Teaching Pastor at Ironwood Church in the Phoenix metro area and author of “Authentic Masculinity: Leaving Behind the Counterfeits for God’s Design.” We then had Hutz Hertzberg join us to talk about the growing hunger for Christ-centered education, explaining why parents are rethinking their children’s schooling and how classical Christian education offers an alternative rooted in biblical truth. Hutz is the chairman at Hope in Truth and currently the Chief Education Officer of Turning Point USA’s education arm, Turning Point Education. You can hear the highlights of today’s program on the Karl and Crew Showcast. If you're looking to hear a particular segment from the show, look at the following time stamps:Dr. Fuz Rana [ 20:17 ]Seth Troutt [ 33:57 ]Hutz Hetzberg [ 11:49 ]Donate to Moody Radio: http://moodyradio.org/donateto/morningshowSee omnystudio.com/listener for privacy information.

ReferencesInt.J. Mol. Sci. 2024, 25(21), 11469Scientific Reports 2016. volume 6, Article number: 28633 Guerra, DJ.2026. Unpublished LecturesSchubert, F. 1822. Symphony 8 in B Minor. D.759.Unfinishedhttps://music.youtube.com/watch?v=3tisvEpblig&si=Muk_sMfUKhgnB6KV

Today, on Karl and Crew, we kicked off our weekly theme, “Chivalry.” Dr. Fazale Rana, also known as Dr. Fuz, joined us to discuss how biochemistry points to God’s design, explaining that discoveries in DNA and the unique human capacities for altruism, empathy, and chivalry reflect what it means to be made in the image of God. Dr. Fuz is the President, CEO, and Senior Scholar at Reasons to Believe, a non-profit that focuses on revealing God in science. Next, Seth Troutt joined us to talk about authentic masculinity, explaining how men can reject counterfeits such as passivity and toxic masculinity by pursuing godly character, Christlike responsibility, and biblical chivalry. Seth is the Teaching Pastor at Ironwood Church in the Phoenix metro area and author of “Authentic Masculinity: Leaving Behind the Counterfeits for God’s Design.” We then had Hutz Hertzberg join us to talk about the growing hunger for Christ-centered education, explaining why parents are rethinking their children’s schooling and how classical Christian education offers an alternative rooted in biblical truth. Hutz is the chairman at Hope in Truth and currently the Chief Education Officer of Turning Point USA’s education arm, Turning Point Education. You can hear the highlights of today’s program on the Karl and Crew Showcast. If you're looking to hear a particular segment from the show, look at the following time stamps:Dr. Fuz Rana [ 20:17 ]Seth Troutt [ 33:57 ]Hutz Hetzberg [ 11:49 ]Donate to Moody Radio: http://moodyradio.org/donateto/morningshowSee omnystudio.com/listener for privacy information.

Today, on Karl and Crew, we kicked off our weekly theme, “Chivalry.” Dr. Fazale Rana, also known as Dr. Fuz, joined us to discuss how biochemistry points to God’s design, explaining that discoveries in DNA and the unique human capacities for altruism, empathy, and chivalry reflect what it means to be made in the image of God. Dr. Fuz is the President, CEO, and Senior Scholar at Reasons to Believe, a non-profit that focuses on revealing God in science. Next, Seth Troutt joined us to talk about authentic masculinity, explaining how men can reject counterfeits such as passivity and toxic masculinity by pursuing godly character, Christlike responsibility, and biblical chivalry. Seth is the Teaching Pastor at Ironwood Church in the Phoenix metro area and author of “Authentic Masculinity: Leaving Behind the Counterfeits for God’s Design.” We then had Hutz Hertzberg join us to talk about the growing hunger for Christ-centered education, explaining why parents are rethinking their children’s schooling and how classical Christian education offers an alternative rooted in biblical truth. Hutz is the chairman at Hope in Truth and currently the Chief Education Officer of Turning Point USA’s education arm, Turning Point Education. You can hear the highlights of today’s program on the Karl and Crew Showcast. If you're looking to hear a particular segment from the show, look at the following time stamps:Dr. Fuz Rana [ 20:17 ]Seth Troutt [ 33:57 ]Hutz Hetzberg [ 11:49 ]Donate to Moody Radio: http://moodyradio.org/donateto/morningshowSee omnystudio.com/listener for privacy information.

Today, on Karl and Crew, we kicked off our weekly theme, “Chivalry.” Dr. Fazale Rana, also known as Dr. Fuz, joined us to discuss how biochemistry points to God’s design, explaining that discoveries in DNA and the unique human capacities for altruism, empathy, and chivalry reflect what it means to be made in the image of God. Dr. Fuz is the President, CEO, and Senior Scholar at Reasons to Believe, a non-profit that focuses on revealing God in science. Next, Seth Troutt joined us to talk about authentic masculinity, explaining how men can reject counterfeits such as passivity and toxic masculinity by pursuing godly character, Christlike responsibility, and biblical chivalry. Seth is the Teaching Pastor at Ironwood Church in the Phoenix metro area and author of “Authentic Masculinity: Leaving Behind the Counterfeits for God’s Design.” We then had Hutz Hertzberg join us to talk about the growing hunger for Christ-centered education, explaining why parents are rethinking their children’s schooling and how classical Christian education offers an alternative rooted in biblical truth. Hutz is the chairman at Hope in Truth and currently the Chief Education Officer of Turning Point USA’s education arm, Turning Point Education. You can hear the highlights of today’s program on the Karl and Crew Showcast. If you're looking to hear a particular segment from the show, look at the following time stamps:Dr. Fuz Rana [ 20:17 ]Seth Troutt [ 33:57 ]Hutz Hetzberg [ 11:49 ]Donate to Moody Radio: http://moodyradio.org/donateto/morningshowSee omnystudio.com/listener for privacy information.

Today, on Karl and Crew, we kicked off our weekly theme, “Chivalry.” Dr. Fazale Rana, also known as Dr. Fuz, joined us to discuss how biochemistry points to God’s design, explaining that discoveries in DNA and the unique human capacities for altruism, empathy, and chivalry reflect what it means to be made in the image of God. Dr. Fuz is the President, CEO, and Senior Scholar at Reasons to Believe, a non-profit that focuses on revealing God in science. Next, Seth Troutt joined us to talk about authentic masculinity, explaining how men can reject counterfeits such as passivity and toxic masculinity by pursuing godly character, Christlike responsibility, and biblical chivalry. Seth is the Teaching Pastor at Ironwood Church in the Phoenix metro area and author of “Authentic Masculinity: Leaving Behind the Counterfeits for God’s Design.” We then had Hutz Hertzberg join us to talk about the growing hunger for Christ-centered education, explaining why parents are rethinking their children’s schooling and how classical Christian education offers an alternative rooted in biblical truth. Hutz is the chairman at Hope in Truth and currently the Chief Education Officer of Turning Point USA’s education arm, Turning Point Education. You can hear the highlights of today’s program on the Karl and Crew Showcast. If you're looking to hear a particular segment from the show, look at the following time stamps:Dr. Fuz Rana [ 20:17 ]Seth Troutt [ 33:57 ]Hutz Hetzberg [ 11:49 ]Donate to Moody Radio: http://moodyradio.org/donateto/morningshowSee omnystudio.com/listener for privacy information.

Today, on Karl and Crew, we kicked off our weekly theme, “Chivalry.” Dr. Fazale Rana, also known as Dr. Fuz, joined us to discuss how biochemistry points to God’s design, explaining that discoveries in DNA and the unique human capacities for altruism, empathy, and chivalry reflect what it means to be made in the image of God. Dr. Fuz is the President, CEO, and Senior Scholar at Reasons to Believe, a non-profit that focuses on revealing God in science. Next, Seth Troutt joined us to talk about authentic masculinity, explaining how men can reject counterfeits such as passivity and toxic masculinity by pursuing godly character, Christlike responsibility, and biblical chivalry. Seth is the Teaching Pastor at Ironwood Church in the Phoenix metro area and author of “Authentic Masculinity: Leaving Behind the Counterfeits for God’s Design.” We then had Hutz Hertzberg join us to talk about the growing hunger for Christ-centered education, explaining why parents are rethinking their children’s schooling and how classical Christian education offers an alternative rooted in biblical truth. Hutz is the chairman at Hope in Truth and currently the Chief Education Officer of Turning Point USA’s education arm, Turning Point Education. You can hear the highlights of today’s program on the Karl and Crew Showcast. If you're looking to hear a particular segment from the show, look at the following time stamps:Dr. Fuz Rana [ 20:17 ]Seth Troutt [ 33:57 ]Hutz Hetzberg [ 11:49 ]Donate to Moody Radio: http://moodyradio.org/donateto/morningshowSee omnystudio.com/listener for privacy information.

Today, on Karl and Crew, we kicked off our weekly theme, “Chivalry.” Dr. Fazale Rana, also known as Dr. Fuz, joined us to discuss how biochemistry points to God’s design, explaining that discoveries in DNA and the unique human capacities for altruism, empathy, and chivalry reflect what it means to be made in the image of God. Dr. Fuz is the President, CEO, and Senior Scholar at Reasons to Believe, a non-profit that focuses on revealing God in science. Next, Seth Troutt joined us to talk about authentic masculinity, explaining how men can reject counterfeits such as passivity and toxic masculinity by pursuing godly character, Christlike responsibility, and biblical chivalry. Seth is the Teaching Pastor at Ironwood Church in the Phoenix metro area and author of “Authentic Masculinity: Leaving Behind the Counterfeits for God’s Design.” We then had Hutz Hertzberg join us to talk about the growing hunger for Christ-centered education, explaining why parents are rethinking their children’s schooling and how classical Christian education offers an alternative rooted in biblical truth. Hutz is the chairman at Hope in Truth and currently the Chief Education Officer of Turning Point USA’s education arm, Turning Point Education. You can hear the highlights of today’s program on the Karl and Crew Showcast. If you're looking to hear a particular segment from the show, look at the following time stamps:Dr. Fuz Rana [ 20:17 ]Seth Troutt [ 33:57 ]Hutz Hetzberg [ 11:49 ]Donate to Moody Radio: http://moodyradio.org/donateto/morningshowSee omnystudio.com/listener for privacy information.

ReferencesJ Clin Invest. 2022;132(23):e152868Int.J. Mol. Sci. 2024, 25(21), 11469 PLoS One 2014 Nov 25;9(11):e113939. Guerra,DJ.2026.Unpublished LecturesLennon/McCartney. 1964 Twist and Shouthttps://open.spotify.com/track/5ZBeML7Lf3FMEVviTyvi8l?si=ba313e3affec403b

Send us Fan MailKyle Peche became severely ill at the age of 18, when people should be filled with energy and good health. He was experiencing extreme brain fog, debilitating fatigue, severe constipation, GI issues, joint pain, skin rashes, and dozens of other symptoms. After many years of obsessive research, he finally found his way to health through systematic, step-by-step detoxification & Mineral-Balancing.Mineral Balancing is a holistic healing science that heals most ailments without the use of drugs. It uses Hair Tissue Mineral Analysis (HTMA) as a compass, which guides directions regarding precise supplement, detoxification, diet, and lifestyle recommendations based on the HTMA that move the body towards more balanced biochemistry, which maximizes the body's cellular energy. The body in turn heals itself, which causes not only elimination of symptoms, but also better quality of life!With a passion ignited from his own suffering, Kyle has now coached hundreds of people to higher health through proper full body detoxification & cellular rejuvenation.Find Kyle at-https://www.jyotimineralbalancing.com/IG- @kyle_pecheYT- @Jyoti Mineral BalancingTHE REJUVINATION ROADMAP MASTERCLASS! Sign up here for FREE!https://www.jyotimineralbalancing.com/masterclass-sign-upFind Boundless Body at-myboundlessbody.comBook a session with us here! 

Your gastrointestinal tract is home to hundreds of bacterial species that play essential roles in digestion and metabolism. As this field of research expands it is becoming increasingly clear that these microbes influence systems beyond the gut: they can even impact brain functioning. These effects were once thought to occur indirectly over the span of minutes to hours through complex chemical signaling pathways. Over the past 15 years, however, scientists have discovered that gut bacteria can communicate directly with the brain via the nervous system, transmitting signals in a matter of seconds and reshaping how we understand the gut–brain axis. This week, we're joined by Kevin Rice, a fourth-year PhD candidate in the Department of Microbiology, co-advised by Dr. Maude David and Dr. Kenton Hokanson. Kevin's research focuses on how human gut cells interact with neurons and the role that the microbiome may play in influencing neurodevelopmental disorders. Through his work across both Microbiology and Biochemistry & Biophysics, he combines computational approaches with neuroscience techniques to better understand the big impact our microbial communities can have on human health. Tune in this Sunday, June 7th at 7 PM to hear Kevin talk about how pursuing scientific questions has shaped his perspective on what constitutes a worthwhile career and the implications of his work in understanding neurodevelopmental disorders.

references Front Immunol . 2019 May 31:10:1187Cells 2020, 9(1), 228Guerra, DJ.2026. unpublished Lectures.Schubert, F 1826. (June). Quartet in G Major. D887.https://music.youtube.com/watch?v=9One__hAjrI&si=spHOFmdbCmMWdqp1

ReferencesInt J Mol Sci. 2019 Mar; 20(5): 1223Guerra, DJ. 2026. Unpublished LecturesMemphis Slim/Eric Clapton. 1972. Steppin Out. Live Cream Vol IIhttps://music.youtube.com/watch?v=XAB6K-5XWU4&si=NYtJSKh9lvYhxu8T

Bruce Lipton famously said that The Matrix is more a documentary than a movie. And that to be truly free, humans must escape the subconscious programming they have been subjected to since childhood. In this episode from the Align Podcast, Bruce Lipton explains why fear may be at the root of most modern illness, how beliefs shape biology through epigenetics, and why 95% of our lives are driven by subconscious programs. We also explore self-love, stress, healing, personal responsibility, psychedelics, consciousness, and practical ways to reprogram the mind. ALIGN PODCAST EPISODE #598 IS SPONSORED BY:

ReferencesNature Reviews Genetics 2019. volume 20, pages 657–674Int.J. Mol. Sci. 2014, 15, 16848-16884Nat Cell Biol. 2019 Mar; 21(3): 397–407.Cell. 2006. Volume 126, Issue 3, 11 August Pages 503-514Circ Res. 2018 Sep 14; 123(7): 868–885. DNA Repair (Amst) 2019 Nov:83:102640Guerra,DJ.2026. Unpublished LecturesSchubert, F. 1826. Symphony 9 in C Major D.944https://music.youtube.com/watch?v=TPpvJnwf5BU&si=pkO5rekCvtw9AHNv

References eLife 2020;9:e55828 DOI:10.7554/eLife.55828Cell Death Discovery2024.  10, Article number: 231 Int J Mol Sci. 2017 Sep 15;18(9):1979Guerra, DJ.2026. Unpublished lecturesHunter/Lesh 1970. Box of Rainhttps://open.spotify.com/track/7x2xjJV3YAPeLQJ7u3Kjet?si=37646e5c42584619

ReferencesJ Pineal Res. 2017 Sep 6;63(4):e12440Nature Reviews | Cancer Reviews2019. 19 | AUGUST 2019 :pp. 439J Exp Clin Cancer Res 2022. 41, 268.Front. Genet., 11 March 2015 Sec. Cancer Genetics Volume 6 - 2015 | https://doi.org/10.3389/fgene.2015.00094 Pathol Oncol Res 2022 Aug 19:28:1610401Guerra, DJ.2026.Unpublished LecturesPorter, C. I1944. Love You Bing Crosbyhttps://music.youtube.com/watch?v=U2Ehu42-mik&si=tkpg8dJxk2TdBvQPAhlert and Turk. 1928. 1944 I'll Get By. Harry James and Orchestrahttps://music.youtube.com/watch?v=8KhO3g5kY0c&si=fXWDc4ZheJ658A1xBeethoven, LV. 1804. Symphony V. C Minor Op 67https://music.youtube.com/watch?v=q_kw904K2bw&si=qDRCnK5UVDi1-9w2

ReferenceseLife 2020;9:e55828 DOI:10.7554/eLife.55828 Int J Mol Sci 2017 Sep 15;18(9):1979 Genes (Basel) 2021 Aug 31;12(9):1370Guerra, DJ.2026. Unpublished LecturesDylan, B. 1964. My Back Pages. Byrdshttps://open.spotify.com/track/1yexhSDARSLVvRCBU3wDAm?si=56d728e0cdcd42a4Winwood/Capaldi, 1970. Empty Pages. Traffichttps://open.spotify.com/track/4UhB17vQsTP0qM9grc4ZUi?si=636948e5ac7f457eSeger,B. 1972. Turn the Page.https://open.spotify.com/track/3P2XAL8UpPBM3nfvuEjHHE?si=47130e77f3ae4729

ReferencesOpen Heart. 2022 Dec 15;9(2):e002171.J Pineal Res. 2017 Sep6;63(4):e12440Int J Mol Sci. 2022 Feb 8;23(3):1905Guerra, DJ. 2026 Unpublished LecturesMozart, WA.1785/1786. Piano Concerti 22&23 . E flat and A major K.282 and 488,https://music.youtube.com/playlist?list=OLAK5uy_lkoFk_2RmT1POq5-0idPoWwAVX5U_yOAk&si=p-m9VoElWiZRURrS

Jessica has had a cool path in biochemistry, with work in both academia and industry, as well as an internship at the National Institutes of Health. She is the Director of New Product Development at LCG Clinical Diagnostics, where she oversees the R&D department. In addition to her work at LCG Clinical Diagnostics, Jessica has been an enthusiastic volunteer for both the Maine Science Festival and the Bioscience Association of Maine's Bioscience Day. This conversation was recorded in May 2026. ~~~~~The Maine Science Podcast is a production of the Maine Discovery Museum. It is recorded at Discovery Studios, at the Maine Discovery Museum, in Bangor, ME. The Maine Science Podcast is hosted and executive produced by Kate Dickerson; edited and produced by Scott Loiselle. The Discover Maine theme was composed and performed by Nick Parker. To support our work: https://www.mainediscoverymuseum.org/donate. Find us online:Maine Discovery MuseumMaine Discovery Museum on social media: Facebook Instagram LinkedIn Bluesky YouTubeMaine Science Podcast on social media: Facebook Instagram YouTubeMaine Science Festival on social media: Facebook Instagram LinkedIn YouTube© 2026 Maine Discovery Museum

Severe seizures, nonstop crying, and an exaggerated startle reflex marked the beginning of Elliott's journey with molybdenum cofactor deficiency type A (MOCD type A), an ultra-rare inherited metabolic disorder that can cause devastating neurological damage shortly after birth. After initially being told that Elliott would likely not survive to school age, his family was offered access to an experimental treatment that changed the course of his life. In this episode of On Rare, David Rintell, Head of Patient Advocacy at BridgeBio, and Mandy Rohrig, Senior Director of Patient Advocacy at BridgeBio, travel to England to meet Elliott and his family and hear how they navigated diagnosis, uncertainty, and hope after already experiencing the heartbreaking loss of another child. Geoff and Lucy, Elliott's parents, reflect on the emotional toll of diagnosis, the realities of managing complex medical care at home, and the joy of watching Elliott grow, attend mainstream school, and live life alongside his siblings. Their story highlights the importance of early diagnosis, caregiver resilience, and the life-changing impact of treatment for rare disease families. Dr. Günter Schwarz, Professor of Biochemistry at the University of Cologne and a leading expert in MOCD, provides a medical overview of the condition. MOCD is a rare inherited metabolic disorder caused by the body's inability to produce molybdenum cofactor, which is required for several critical enzymes to function properly. Without it, toxic sulfite builds up in the body, particularly in the brain, leading to severe seizures, neurological injury, and often early death. Dr. Schwarz explains how the condition is inherited, why symptoms begin so early in life, and how targeted treatment can dramatically alter outcomes when started quickly after diagnosis.

ReferencesInt. J. Mol. Sci. 2023, 24(4), 3120Cell Death & Differentiation 2021. v28, pages 3357–3370Neuropsychiatr Dis Treat. 2025 Sep 10;21:2035–2052. JACCCardiovasc Interv.2025 Apr 28;18(8):963-971Guerra, DJ.2026. Unpublished LecturesBiber, HIF.. 1674. Passagalia C.105https://music.youtube.com/watch?v=MohWMCmO3SE&si=1BjlIDO7HuI_GxaM Jagger/Richards. 1970 Wild Horses Rolling Stoneshttps://open.spotify.com/track/4M4Q3JLsUbyTkd5WHty1WB?si=81cc8e5c47d74958

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This month, Mary met up with Dr. Beronda Montgomery, a plant biologist, writer, researcher and scholar. Dr. Montgomery works to understand how individuals perceive, respond to, and are affected by the environments in which they live. By investigating the response of photosynthetic organisms (i.e., plants and cyanobacteria) to external light cues, she is able to identify related roles for innovative leaders in human settings.After over 18 years at Michigan State University as a Foundation Professor in Biochemistry, Molecular Biology, Microbiology and Molecular Genetics, Beronda served as Vice President for Academic Affairs, Dean, and Professor of Biology at Grinnell College. In that time, she co-founded the annual Black Botanists Week. Then, since 2025, she's been the Sally Starling Seaver Fellow in Biological Sceinces with Radcliffe Harvard Institute.In this episode, Mary and Beronda speak of her most recent book, When Trees Testify. As Beronda writes, "Plants don't just passively provide. They also take action. They are masters of adaptation. They 'know' what and who they are, and they use this knowledge to make a way in the world. Plants are even capable of transformative behaviors that allow them to maximize their chances of survival in dynamic and sometimes unfriendly environments." Quite consistent with the rich spirit of her words here, this HILFH conversation was rich and enlivening. You can learn more about Beronda Montgomery by checking out her books, When Trees Testify and Lessons from Plants. Also spend some time with her website and the additional writings there. Let yourself be informed and inspired by Dr. Montgomery and the love of plants.MUSICRolled Ankles. Music by Nicholas Panek from PixabayMoonlight on Your Hands. Music by Mircea Iancu from PixabayEvening Strings. Music by DPStudioMusic from PixabayOriginal theme music composed and performed by Gary Ferguson.----HILFH is an educational project of Full Ecology. Check us out and let us hear from you.

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ReferencesDev Cell. 2023 Apr10;58(7):597-615.e10.CurrentBiology.2024. V.34, Issue 21pR1067-R1068November 04.RNA.2020 Aug;26(8):903–909Sci Rep. 2015. volume 5,Article number: 15292 SciRep. 2025 Jul 14;15(1):25389.Guerra, DJ.2026.Unpublished LecturesLennon/McCartney. 1967. Good Morning Good Morninghttps://open.spotify.com/track/0xIuNHHcKI1JDuBPlSwzb1?si=d9a84805b0144608Mozart, WA. 1785. The Haydn Quartets. Op 10.https://music.youtube.com/playlist?list=OLAK5uy_nFz2DrhfPWUriYaJw44iN4p4hBuem83Sc&si=j8s78fyUsC08bKTe

ReferencesJ Hum Evol.2022 Oct; 171: 103229. Am J Physiol Cell Physiol 2022. 322: C125–C135J Neuroinflammation. 2016 May16;13(1):109. doi:10.1186/s12974-016-0575-xPrz Menopauzalny. 2017 Jun; 16(2): 51–56Genes & Immunity2021. volume 22, pages 125–140 Dev Cell. 2023 Apr10;58(7):597-615.e10.Scientific Reports 2015.volume 5,Article number: 15292 Guerra, DJ.2026.Unpublished LecturesShubert, F Liszt,F. 1826. Standchen. Khatia.https://music.youtube.com/watch?v=9h35VSz2Kkc&si=28EA6Y5mCETviBmuJohn, E.1972. Mona Lisas and Mad Hatters,https://open.spotify.com/track/3AJVI8kKij8zD5YOR6HM9v?si=908210d10c594781

Mehlman Qbanks: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://qbanks.mehlmanmedical.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠IG: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/mehlman_medical/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Main Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://mehlmanmedical.com/⁠

ReferencesJ of Cellular Physiology 2026 Volume241, Issue5 May e70190PPAR Res. 2010 Sep 26;2010:61208Guerra, DJ. 2026. Unpublished LecturesMiller, S. 1970. Steve Miller Band V.https://music.youtube.com/playlist?list=OLAK5uy_mMurbyyiMLz7bvTAJmI_j8sCs_e-NbvAM&si=U7RzDJWU9CtB_oCU

Lipoprotein(a) or Lp(a) is suddenly all the rage because several drug companies are working on medications to lower this previously resistant form of cholesterol. Almost entirely genetic, unaffected by diet or lifestyle, it has numerous studies linking it to heart disease and aortic valve calcification. But it may not be the ticking time bomb some influencers like to claim.   Become a supporter of our show today either on Patreon or through PayPal! Thank you! http://www.patreon.com/thebodyofevidence/ https://www.paypal.com/donate?hosted_button_id=9QZET78JZWCZE   Email us your questions at thebodyofevidence@gmail.com.   Editor:    Robyn Flynn Theme music: “Fall of the Ocean Queen“ by Joseph Hackl Rod of Asclepius designed by Kamil J. Przybos Chris' book, Does Coffee Cause Cancer?: https://ecwpress.com/products/does-coffee-cause-cancer   Obviously, Chris is not your doctor (probably). This podcast is not medical advice for you; it is what we call information. References: The genetic nature of Lp(a) levels: https://pubmed.ncbi.nlm.nih.gov/1386087/ Prevalence of elevated Lp(a) in 500,000 US patients https://pubmed.ncbi.nlm.nih.gov/27659098/ Prevalence of elevated Lp(a) in 2.9 million Chinese adults https://pubmed.ncbi.nlm.nih.gov/40266173/ Prevalence of elevated Lp(a) in the INTERASPIRE study https://pubmed.ncbi.nlm.nih.gov/40436467/ Variation of Lp(a) by sex: https://pubmed.ncbi.nlm.nih.gov/27659098/ One of the many studies linking Lp(a) to cardiovascular disease https://pubmed.ncbi.nlm.nih.gov/33115266/ High Lp(a) and aortic stenosis: https://www.nejm.org/doi/full/10.1056/NEJMoa1109034 FH and Lp(a) https://pubmed.ncbi.nlm.nih.gov/32466883/ The ongoing Lp(a) trials https://familyheart.org/lpa-clinical-trials  

ReferencesFront. Endocrinol., 2019. 02 July Sec. Molecular and Structural Endocrinology Volume 10 -J Cell Physiol. 2026 May;241(5):e70190Thromb Haemost.2009 Sep;102(3):544–554.Guerra, DJ. 2026.Unpublished LecturesCahn and Heusen. 1957. All The Way Frank Sinatrahttps://open.spotify.com/track/7fanCwOck16J9MPJ3SR39P?si=df1d1051137648f4Dvorak, A. 1983. American String Quintet 3. E Flat Major OP.97https://music.youtube.com/watch?v=cip5TJ7H4jg&si=kOTQNlmy93LDJNvL

In this episode of Tiny Show and Tell Us, a listener asks: Could we still be carrying air from our very first breath? Deboki unpack's residual lung volume, gas exchange, and a forensic technique used to determine whether or not someone drowned. Then, the conversation turns to women's health and bleeding disorders after a listener shares their experience living with Von Willebrand disease — the most common bleeding disorder. Sam explores what the condition is, how it was discovered, why it disproportionately affects women, and how normalizing heavy, painful periods is not just frustrating but has serious medical consequences.Check out Pale Blue Pod here or wherever you get podcasts!We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured.A transcript and references for this episode can be found at acs.org/tinymatters.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this episode of Medsider Radio, we sat down with Antony Odell, co-founder and CEO of Echopoint Medical.Echopoint is a London-based UCL spinout developing iKOr, an optical microcatheter for coronary diagnostics.Antony brings over 30 years of medtech experience across Johnson & Johnson, Fresenius, and Stryker, before transitioning into startups as CEO of Tayside Flow Technologies and Tissue Regenix. He holds a BSc in Physiology and Biochemistry.In this interview, Antony discusses translating academic IP into a commercial device, choosing early clinical sites to balance speed and learning, managing non-dilutive funding as a long-term discipline, and outlines the most important responsibilities of an early-stage medtech CEO.Before we dive into the discussion, I wanted to mention a few things:First, if you're into learning from medical device founders and CEOs and want to know when new interviews are live, head over to Medsider.com and sign up for our free newsletter.And if you're ready to level up your medtech game, you should check out Medsider Courses — 8-week masterclasses covering topics like fundraising, M&A and exit planning, design and development, clinical and regulatory strategy, and commercialization.These courses, featuring hard-earned lessons from elite medtech CEOs, can be purchased individually or come free with our All-Access Pass.If you'd rather read than listen, here's a link to the full interview with Antony Odell, which includes a link to ScottBot — an AI version of host Scott Nelson trained on every Medsider interview and playbook. Feel free to ask ScottBot any questions you'd like!KEY MOMENTS FROM THE INTERVIEW(03:06) - How Antony's career centered on translating clinical insights into commercial reality (05:54) - What Echopoint's iKOr does, and why 40% of cath lab patients leave without a diagnosis (12:13) - How Echopoint landed its first U.S. clinical site, and what that means for the company (13:48) - What to assess before spinning out an academic idea, and why clinician input is the first real test (20:14) - Why Echopoint chose Barts over typical sites for its first-in-human study (22:58) - How getting too close to one clinical site can lead to dangerous groupthink (30:54) - Why non-dilutive funding belongs on the board agenda permanently (39:54) - How CEOs should manage boards, control information flow, and avoid becoming a “glorified note-taker”

Modern science has given us the ability to edit our genes, life-saving vaccines, and glimpse the origins of the universe. But is the same system holding itself back? Critics argue that the pressure to publish and fierce competition for funding rewards safe, incremental work over bold thinking. Others see a system still capable of paradigm-shifting discoveries — one where global collaborations and long-term thinking motivate scientists to pursue grand, ambitious ideas. Now we debate: Is the Scientific Enterprise Too Risk-Averse?  This debate was produced in partnership with the Stavros Niarchos Foundation (SNF) Agora Institute at Johns Hopkins University, as part of The Hopkins Forum series. Arguing Yes:  Tyler Cowen, Author of "The Great Stagnation"; Economics Professor at George Mason University; Founder of Emergent Ventures; Host of "Conversations with Tyler" podcast   Brandon Ogbunu, Computational Biologist; Associate Professor of Ecology and Evolutionary Biology at Yale University; Professor at the Santa Fe Institute  Arguing No:   Kate Biberdorf (“Kate the Chemist”), Professor for the Public Understanding of Science and the Department of Chemistry & Biochemistry at the University of Notre Dame; Science Entertainer  The Honorable Sethuraman Panchanathan, 15th Director of the National Science Foundation; University Professor of Technology and Innovation and Foundation Chair at Arizona State University  Emmy award-winning journalist John Donvan moderates  Join the conversation on Substack—share your perspective on this episode and subscribe to our weekly newsletter for curated insights from our debaters, moderators, and staff.  Follow us on YouTube, Instagram, LinkedIn, X, Facebook, and TikTok to stay connected with our mission and ongoing debates.  Learn more about your ad choices. Visit podcastchoices.com/adchoices