Podcasts about Parkinson

Hour 1 for 6/15/26 Drew welcomes Dr. William Supple, PhD to discuss his book Cancer is a Parasite (1:00). Topics: if taking Fenbendazole can be preventative (21:35), Parkinson's (31:40), myeloma (36:27), Ivermectin (37:10), Fenbendazole (41:19), and HPV (45:14). Link: Cancer is a Parasite Book Original Air Date: 6/1/26

We're excited to welcome Stephanie Prestridge to the Tactical Living Podcast

At 70 years old, Jeff broke four ultra-distance cycling world records in a single day, and he did it after training for only a few months. On this episode of The Upgraded Man Podcast, host Chris Anderson sits down with the record-breaking cyclist, former aerobatic pilot, and performance coach to take apart one of the most common excuses men hide behind: a lack of motivation. Jeff makes the case that motivation is overrated, and that the real engine behind a life of achievement is learning to enjoy the process, set the right goals, and pivot without shame when something stops serving you. In this episode, you will learn: Why motivation is overrated and enjoying the process is what actually sustains long-term effort The difference between quitting and "pivoting," and why Jeff reframes walking away as a strength rather than a failure How to set goals that are "50 percent believable" so they never become a to-do list or a pipe dream The four-stage path to mastery: discovery, training, practice, and teaching, and how to copy it from a skill you already have Why complacency is the real enemy, and the rare moments when it actually works in your favor How a safety net makes a career or life pivot responsible instead of reckless What overtraining taught Jeff about the gap between hating an activity and hating how it makes you feel Why writing down your strengths and challenges gives your goals real power Jeff is a cycling and performance coach who has set multiple records through the World Ultra Cycling Association, competed for years as an aerobatic pilot, and raised roughly $15,000 for his local Parkinson's community. His approach blends decades of athletic experience with a coaching philosophy focused on building people up, not just making them faster. Learn more and connect with Jeff at JeffsCoaching.com. If this conversation pushed you to reconsider something you have been avoiding, subscribe to The Upgraded Man Podcast, leave a review, and share this episode with a man who is ready to pivot. This episode may or may not be sponsored. Some product links are affiliate links, meaning we'll receive a small commission if you buy something.===========================⚡️ PODCAST: Subscribe and listen on all major platforms⚡️ Want to be a guest on The Upgraded Man? Apply here ➡ https://upgraded-man.com/guest⚡️ For support or business inquiries, email us ➡ chris@upgraded-man.com Our mission at The Upgraded Man is simple — help men upgrade every area of their life through real conversations, honest stories, and actionable insight from men who have done the work.The content on The Upgraded Man is for informational and entertainment purposes only. The views expressed by the host and guests are their own and do not constitute professional legal, financial, medical, or therapeutic advice. Always consult a qualified professional before making decisions based on information discussed on this podcast. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

What if the career you've been dreaming of has been waiting for you all along even after years of burnout and doubt? Today's guest is proof that it's never too late to start. Her journey began long before she officially launched her practice with a quiet but persistent vision of doing therapy differently.I'm excited to introduce you to Angela Ruiz, a speech-language pathologist and private practice owner whose journey into entrepreneurship was years in the making. She is the owner of Angela Ruiz SLP Services, PLLC in Houston, Texas.Long before she officially launched her practice, Angela had a vision of creating a space where care felt more personal, more connected, and truly centered around the individual. That vision was years in the making. Throughout her career, she found herself drawn to both pediatric and adult populations, with a special passion for neuro-based therapy and supporting individuals with Parkinson's through programs like LSVT LOUD. But more than any one specialty, what has shaped her path is her belief that therapy should feel human first — grounded in trust, relationships, and real-life impact.Over time, that vision evolved into a business that reflects not just her clinical expertise, but her values, intuition, and the way she believes care should be delivered.After nearly 20 years in the field, working in schools, skilled nursing facilities, and hospitals, Angie knew something had to change. The productivity standards were suffocating. And deep down, she never forgot the dream she had back in grad school: owning her own practice. Her early exposure to the world of private practice, including following the work of Jena, helped plant the seed that this kind of career was possible.In this episode, Angela discusses how she finally broke free from burnout, why "going slow" helped her grow fast, and how she's building a practice that fills her cup instead of draining it.Outside of patient care, Angela is passionate about building a practice that allows her to show up fully — for her clients, their families, and herself — while creating meaningful, lasting change through connection-driven care.In Today's Episode, We Discuss:How a dream she had in grad school planted the seed for private practice nearly two decades before she launchedRecovering from burnout and building something sustainable — on her own terms and her own scheduleThe exact weekly structure she uses to balance clients, admin, and a PRN gigHow "going slow doesn't mean you're not going" — and why that mindset has been the secret to her rapid successAngela is truly proof that it is never too late to build the career and life you've always wanted. Her story doesn't have to be the exception. You, too, can achieve that same level of freedom, fulfillment, and balance if you simply take the first step.Want to build a private practice that gives you back your time, your energy, and your joy—just like Angela did? Learn more about the Start Your Private Practice program, where clinicians like Angela got the tools, community, and confidence to move from clinician to CEO. Visit www.StartYourPrivatePractice.com to get started.Or, if you already have an existing private practice and you're ready to take it to the next level we'd love to support you inside the Next Level Private Practitioner. You can learn more at www.nextlevelprivatepractitioner.com.Whether you want to start from scratch or grow an existing practice, I can help you get the freedom, flexibility, fulfillment, and financial abundance you deserve. Visit www.independentclinician.com to learn more.Resources Mentioned:Follow Angie onFacebook: Angela Ruiz SLP Services, PLLCLinkedIn: www.linkedin.com/in/angela-ruiz-ms-ccc-slp-65a49660Check out her Website: angelaruizslp.comWhere We Can Connect:Follow the Podcast: https://podcasts.apple.com/us/podcast/private-practice-success-stories/id1374716199Follow Me on Instagram: https://www.instagram.com/independentclinician/Follow Me on Facebook: https://www.facebook.com/jena.castrocasbon/

FOVISSSTE cuenta con un programa especial para apoyar a las trabajadoras y pensionadasInicia pago para becarios de Jóvenes Escribiendo el FuturoCientíficos españoles desarrollan interfaz para tratar parkinson y epilepsiaMás información en nuestro podcast#grc

On Saturday, 6 June, at the British Team Championships, I successfully performed a horizontal bar routine—five years after retiring from men's artistic gymnastics.At 33 years old, I wanted to challenge myself and question some of the traditional beliefs that are often accepted within the gymnastics community. This journey was about proving that limitations are not always where we think they are and that meaningful goals can still be achieved long after stepping away from competitive sport.My inspiration for taking on this challenge came from two incredible charities: Parkinson's UK and the Samaritans. Through this effort, I am aiming to raise £2,000 to support the vital work these organisations carry out every day across the UK, helping people affected by Parkinson's and mental health challenges.If you would like to support this cause, please consider making a donation through my GiveWheel fundraising page, which can be found via the link in my Instagram bio or YouTube description.Thank you to everyone who has already donated and supported me throughout this journey. Your generosity and encouragement have meant a great deal.This is my story.

We have talked already about the link between autism and dementia, however a lesser known association is the one between autism and another disorder of aging: Parkinson’s Disease. A recent presentation at INSAR revealed what is known about the relationship, why they are related, what causes the association and what people with autism can do to possibly mitigate the onset of dementia and Parkinson’s Disease. Thank you to Dr. Blair Braden and Samantha Harker and Manuela Velez Galindo from the Autism and Brain Aging Lab at Arizona State University (@autismbrainaginglab @asuresearch) for joining this podcast and explaining the findings so far and what they mean for individuals and families with autism. https://pubmed.ncbi.nlm.nih.gov/25911091

In this episode of the Third Eye Awakening podcast,  I am so excited to have Joshua Baldridge on the show! Joshua has graciously agreed to share his personal Akashic Records Readings on the podcast and I am so excited to share it with you!Joshua is just another seeker on the path of more knowledge, experience, and love.  While growing up in the LDS religion, Joshua was constantly curious about the deeper layers of reality that were unexplained by the paradigm of his youth.  He discovered so much wisdom and light from sources outside of his church, such as the writings of Alice A. Bailey, J.J. Dewey, Laura Knight-Jadczyk, and podcasts such as Third Eye Awakening and This Jungian Life.  These teachers, combined with a crucible of mental health and addiction stemming from the collision of his sexuality with his religious believes, have become pieces of the foundation he is still trying to build today when it comes to understanding the world and being able to move in within it in a way that radiates light and truth—a foundation he will likely build for this and many lifetimes. He is currently studying neuroscience at Boise State University, and has assisted in and presented work on spaceflight's effect on neuronal cells and systems as well as Parkinson's disease research.  While not having any current offerings commercially, Joshua hopes to pursue a career in healthcare, likely counseling, where he can one day help people that also balance the karma of religion, addiction, sexuality, and more.  Joshua is currently well-versed in the tarot, depth psychology, and he is learning astrology.  He hopes to get trained in reiki sometime in the next year.  He will incorporate these modalities someday into a form that allows him to extend a hand of compassion and courage to other pilgrims on this long, winding, wild path that is life.In this episode, Josh and I chat about:-Josh's psychic awakening and the internal pull to let things go-religious framework and karma from growing up in and letting go of the church-past lives in religious enforcement and distinctions between Jesus, Christ, and Christ Consciousness-paranoia, self-destruction, and identity shifts-self-forgiveness as instrumental in healing-learning to trust yourself, your body, and your intuition after years of repression and conditioning-leaning into play in the journey of personal growth… and so much more!CONNECT WITH JOSH@a.nomad.hereMENTIONED IN THIS EPISODEKrystal SmithLINKS MENTIONEDStart Your Spiritual Biz RoadmapFollow me on Instagram 

The Movers & Shakers are back in the pub to talk walking football. We're big fans of activities that help slow down the progression of Parkinson's Disease, particularly walking football; it may even rival ping pong (but not according to Gillian!). We didn't have a kick about in situ but we had some experts in to tell us all about it - and Rory went to his local club to give us a taste of the real thing. With us are the facilitators of the Parkinson's Pioneers Women's Walking Football Community, Annie Booth and Gemma Darvill, as well as member of the Whittington Health NHS Trust-Arsenal walking football programme, Jeremy Munday. If our guests don't inspire you to get moving, we don't know what will!Movers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Associate Producer: Lulu Goad & Ewan CameronMusic by Alex Stobbs Hosted on Acast. See acast.com/privacy for more information.

The "gold-standard" treatments for Parkinson's Disease may be working against each other. Ultrasound isn't just for imaging. Should food companies pay the FDA? Sleep apnea may silently rewire the brain. Facebook: ingoodhealthpodX: @ ingoodhealthpodIG: @ingoodhealthpodYouTube: @ingoodhealthpodSpotify Apple Podcast In Good Health PodcastSubscribed to the newsletterFull ArchiveContact UsBecome an Affiliate Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Shahayra Majumder and Jonathan Chizever - Hydrate IV Bar Madison, WI On Focusing on What Really Matters: "They're passionate about their health, which is your only wealth at the end of the day." What good is money if you're spending your time hurting and not able to enjoy this great gift of life that we have all been given?  Health is arguably the most important thing to focus on, to make sure you can do the things you want to do.  Whether that is growing a business or enjoying time with friends. Shahayra and Jonathan set out to help boost the health of the midwest by starting a Hydrate IV Bar franchise in Madison, Wisconsin. Through our candid conversation you will learn what is a IV bar, why do people get IV drips and how they started this business in the IV drip world. Learn how they identified a gap in the Midwest's wellness market, navigated the highly regulated and rapidly evolving IV bar industry, and brought a community-focused approach to health and hydration. Are you curious about how IV therapy went from hospital wards to vibrant wellness lounges?  Or what it takes to build a franchise rooted in both science and local values?  This conversation will open your eyes to the business challenges, customer stories, and passion that drive this growing trend. Shahayra and Jonathan share some great insights into franchise selection, the science behind vitamin infusions, building a winning team, and the power of connection within a unique new “third space” for health-minded people. Listen as they explain the power of IV drips and how they can help you in your health and life journey. Enjoy! Visit Shahayra and Jonathan at: https://hydrateivbar.com/locations/madison/ Sponsors: Calls On Call Extraordinary Answering Service, phone answering for small businesses: https://callsoncall.com Some videos have been recorded with Riverside: https://www.riverside.fm/?utm_campaign=campaign_5&utm_medium=affiliate&utm_source=rewardful&via=james-kademan   Podcast Overview: 00:00 Bringing IV therapy to Madison 05:39 Navigating Franchise Regulations 07:47 IV therapy goes mainstream in Tokyo 12:50 Curated med spa offerings 14:44 Choosing Hydrate IV Bar for Madison 19:02 Starting with franchise questions 20:37 Building a Health-Focused Community 24:53 Benefits of Vitamin D Supplementation 27:55 Challenges with supplement patents 32:20 Functional medicine consultations at Hydrate 34:08 Patient advocacy and safe care 39:05 Frequency of sessions per week 41:33 Supplements and their credibility 47:04 Choosing the right location 48:42 Optimizing franchise location space 52:48 Hiring nurses for IV procedures 56:16 Spa services and mobile options Podcast Transcription: Jonathan Chizever [00:00:00]: This gentleman with Parkinson's started supplementing the NAD with us, and the results we're seeing are just, like, amazing. He's not perfect in running marathons, but he's walking around without his hunch in his cane. I check in with his wife the next day, like, hey, how's he doing? And she's like, I couldn't believe it. I woke up and I walk out and he was up before me, which is rare. And he's sitting in his chair in the living room, giant smile plastered across his face. And. And it's like, what's going on? And then I see him get out of the chair, stand up with no cane, no hunch, and he's like, I feel better than I felt in a long time because of something that we all. James Kademan [00:00:41]: You have found authentic business adventures business program that brings you the struggle stories and triumphant successes of business owners across the land. Downloadable audio episodes can be found in the podcast link found@drawincustomers.com we are locally unwritten by the bank of Sun Prairie, and today we're welcoming, preparing to learn from Sahara and Jonathan of the Hydrate IV bar. So, Sahara, Jonathan, how are you guys doing today? Jonathan Chizever [00:01:06]: Wonderful. Excited to be here. James Kademan [00:01:08]: Yeah. Shahayra Majumder [00:01:08]: Woot, woot. James Kademan [00:01:09]: Let's talk about Hydrate IV bar. I don't know what in the world an IV bar is, and I bet a lot of people don't either. So let's just start with what is an IV bar? Jonathan Chizever [00:01:18]: Happy to tell them you want to go or want me to go? Shahayra Majumder [00:01:20]: Um, yeah, I'll kick it off if you want to add in, if there's anything that I miss. But have you ever had an IV before? James Kademan [00:01:28]: I had. Yes. I had a saline IV thing when I had a. A gut thing, a stress gut thing Shahayra Majumder [00:01:35]: way back when, probably in the hospital. James Kademan [00:01:37]: Yeah. Yeah. Not a fan. Shahayra Majumder [00:01:39]: Yeah. James Kademan [00:01:41]: Not a fan of being in the hospital. Shahayra Majumder [00:01:42]: Yeah, right. Yeah, I. A lot of people are used to thinking about IVs being something that you get in the hospital or at urgent care in an emerg situation. But an IV bar actually takes those services outside of an emergency situation and lets you be a little more proactive about rapidly rehydrating your body. James Kademan [00:02:04]: All right. Shahayra Majumder [00:02:05]: For your different health and wellness goals. There's lots that we can do with supplementing things that you might be deficient in or if you're just feeling certain ailments that could be improved with additional vitamin supplements, meditation, or hydration. That's usually why people come to an IV bar. For me, it's been more of a proactive thing. I realized as I started doing IVs on a regular basis, I felt more energy. I was getting sick less. I didn't really let anything get me down as much. Like during cold and flu season. Shahayra Majumder [00:02:49]: Yeah. Anything that you would add to that, Jonathan Chizever [00:02:52]: I think that sums it up. Great. Yeah. James Kademan [00:02:54]: All right. How do you get in the IV bar business? Shahayra Majumder [00:02:58]: You take that one. Jonathan Chizever [00:03:01]: So we both, in our travels, neither of us are from Madison. I've been here 10 years. Sahara's been here seven. And we've both, in our travels and living other places, seen this as a more established concept in other places. And, you know, in the Midwest, whether it's fashion trends or wellness modalities, we're generally the last to get just about everything. And so here we are. And so, you know, IVs have saved us in numerous occasions from feeling bad, and really, until we got in the business, didn't yet understand how much it can make you feel good in a consistent and proactive sense. But we just saw this as a market that makes so much sense for it, because, you know, what people traditionally associate it with is hangovers, at least in the selective sense, which it is phenomenal for, I've heard, at least. Jonathan Chizever [00:03:54]: But. But beyond that, you know, like, the founder of our brand, she got into this. She was a Broncos cheerleader, and she noticed all the guys in the team are doing these IVs routinely, all the time. And that was part of her origin story of getting into this. And so athletes love it, and athletes have been ahead of the curve and, you know, taking advantage of this. So for athletics and drinking Madison, we have a lot of bubbles, and turns out. James Kademan [00:04:24]: Yeah, yeah. Jonathan Chizever [00:04:25]: So. And then beyond that, we also have a very vibrant wellness scene. You know, we have a population that likes to take care of themselves. And, I mean, in so many ways, it made sense, but it was something that we saw being severely underserved. So it wasn't like we wanted to start a business. And we're like, what business do we do? It was like we noticed that there was a gap in the availability of these types of services in a place that it makes so much sense to have them. And the rest kind of naturally came from there. James Kademan [00:04:55]: Right on. So did you hunt down a franchise, or did you get introduced to the franchise? And you're like, yes, that's what we want. Shahayra Majumder [00:05:03]: Little column A, little column B. I did interview, like, every franchise under the sun doing IV stuff. James Kademan [00:05:09]: All in the IV stuff. Shahayra Majumder [00:05:10]: Yes. James Kademan [00:05:11]: Okay, how many are we talking here? Shahayra Majumder [00:05:12]: Oh, my God. I think I Started talking to folks in September of 2024, and then we signed our franchise agreement February of 25. So, yeah, I mean, that gives you a little gauge. It took me months and months of. James Kademan [00:05:27]: So just talking like, I don't know how many franchise I've seen. Are we talking five? We talking 50? Jonathan Chizever [00:05:32]: Oh, no, I'd say a dozen and a half maybe. Shahayra Majumder [00:05:35]: Yeah, maybe closer to like the 20 or 30. Jonathan Chizever [00:05:37]: Wow. Shahayra Majumder [00:05:39]: Yeah, franchise franchises. And there are a few that dominate the market. There are a few that are bigger. But what's interesting is this industry, it's very highly regulated, but the regulations are different state to state. So if you know a little bit about franchising, you know that franchises have to be registered in every single state. And some states are harder to get registered in. And so I talked to a lot of the folks that I was able to get their franchisees on the phone and get honest opinions about the kind of support they're receiving, how the market has received them. I particularly talk to folks in the Midwest or familiar with the Midwest because, you know, the market in the Midwest is not going to be what it is in, you know, Nashville, Tennessee, for example, where you're getting a lot more tourism and. James Kademan [00:06:38]: Yeah, sober me up. Sober me up. ...

Can stem cells actually repair Parkinson's brain damage? We look at the latest clinical trials showing how regenerative medicine is restoring dopamine function, improving motor control, and slowing disease progression - plus what families should know about this experimental frontier. Learn more at https://www.lydianclinic.com/blog/stem-cell-therapy-alzheimers-parkinsons-als/ Lydian Cosmetic Surgery Clinic City: Seoul Address: 836 Nonhyeon-ro, Sinsa-dong, Gangnam Website: https://www.lydianclinic.com/

BONUS: Why Your Organization Is Still a Factory — And What an Octopus Can Teach You About Transformation Phil Le-Brun and Dr. Jana Werner both work inside Amazon, advising Fortune 500 leaders on transformation. But before Amazon, they spent decades in the trenches — Phil as International CIO of McDonald's, Jana leading change in banking and logistics. Together they wrote The Octopus Organization (HBR Press) to explain why most companies are still running on a hundred-year-old factory model, and what the alternative looks like. "We Want to Help You Make Your Own New Interesting Mistakes" "We keep saying, as Phil likes to say, can we help you make your own new interesting mistakes and avoid the mistakes that we see again and again."   Jana and Phil are both practitioners who have led large-scale changes — and made mistakes they're now happy to share. Jana describes working with incredible, smart, thoughtful people inside large organizations who weren't trusted, weren't allowed to do the work they could do, and couldn't be their best selves. She managed to turn teams considered underperforming into rock stars simply by listening and giving them space. Phil saw the same pattern at McDonald's — incredible people who knew the answers but weren't allowed to act on them. A disastrous standardization push from 2002 to 2004 taught him that top-down efficiency mandates don't work. The CEO left, and Phil got the opportunity to tap into people lower in the organization, define a common mission, and start building from there. The Factory Model Nobody Questions "There was no upside for her people taking ownership because you could have career-limiting effects if you made a mistake, if you were seen to be making a mistake or overstepping."   Jana shared two sides of the same problem. A CEO of a large investment company told her he has to sign off on every small decision — and his people assume he wants to. Neither side wants this, but nobody questions the processes in place. On the other side, a COO told Jana "my people don't want ownership." After half an hour of coaching, the COO realized there was no upside for her people to take ownership — mistakes meant career-limiting consequences. Jana is honest about her own experience too: a team member told her she was micromanaging, and she denied it. They created a secret signal — scratching an ear in meetings whenever she micromanaged. He was scratching a lot. Phil adds that what he calls "yoga babble" — abstractions like "we're going to become an agile platform-based culture" — lets leaders avoid saying what they actually mean. Nobody challenges it because the boss said it, and it sounds sort of right. The result: completely meaningless direction. The Octopus — Distributed Intelligence in Practice "It has two thirds of its intelligence, its neurons, in its arms. The arms connect independently — they don't always need a central brain, but they also have one, so they can stay aligned but also work independently."   The octopus has distributed neural clusters in each arm. It can adapt, shape-shift, change the texture of its skin, and even alter its RNA to switch between cold and hot water within hours. For Jana and Phil, this is the organizational metaphor: teams that can think locally and act without waiting for permission from the center, while staying aligned on mission. Phil translates this for team leaders of 8-10 people inside traditional enterprises:   Put together teams with cognitive diversity and encourage constructive conflict — what Linda Hill at Harvard Business School calls "creative abrasion" Invest in the storming, norming, performing cycle instead of cutting through it Leave the "how" to the team — the leader's job is the "why" and the "what" Don't jump to the answer — Einstein said if you have an hour to solve a problem, spend 55 minutes understanding the problem Start executing quickly through rapid experimentation; you can't plan your way to success in novel situations Don't Build the Pedestal — The Monkey Comes First "Get to the most tricky problems first, and try and solve them. If you can't, figure out fast — and if you can't, just stop, because your whole project is useless."   Astro Teller, CEO of Alphabet X's Moonshot Labs, says: "If you want to teach a monkey on a pedestal to recite Shakespeare, don't start by building the pedestal." Jana explains that organizations, once they get a project through the gauntlet of approvals and business cases, start working on the easy, visible things to show progress — the pedestal. But if you can't get the monkey to speak, the pedestal is useless. The counterintuitive move: when passionate people dispassionately tell you the hard problem isn't solvable, give them hugs, put them on a pedestal themselves, give them bonuses — because they just freed up resources for something better. Phil reinforces that this isn't a money problem. At McDonald's, before building a handheld order-taking device, they built a block of wood to test how comfortable it was to hold. Organizations waste far more money trying to plan for things they can't possibly plan for than they would by running quick experiments. Single-Threaded Leaders — The Pig at Breakfast "Who's that person waking up every morning saying, are we actually putting the focus on the things that are going to get us to the finish line of delivering value — not within my function, but across the organization?"   Phil tells the classic joke: a pig and chicken are walking down the road. The chicken says "let's open a restaurant." The pig asks what they'll sell. "Ham and eggs, of course," says the chicken. The pig stops: "I need to be far more committed than you." Organizations are full of chickens — people who lay their half-baked decisions, want to sign off, want to say no. What's needed are pigs. Amazon calls them single-threaded leaders. Apple calls them directly responsible individuals. The key: one person owns an initiative end to end, waking up every morning focused on delivering value across the organization, not just within their function. Mow the Lawn — Bureaucracy Grows While You Sleep "Your bureaucracy grows while you sleep. Think about your bureaucracy like mowing a lawn. You can't mow a lawn once."   Jana references Parkinson's Law — a senior Royal Navy leader found that even as the fleet shrank, the number of administrators grew by 5-10% annually. This applies to every organization. Middle managers fill their time by adding processes. One person's mistake becomes a process that penalizes 10,000 people. The solution is continuous gardening. At Google, a senior leader added positive friction: if you want more than 5 interviews in the hiring process, you need my approval. At Amazon, the principle "invent and simplify" asks everyone every year: what are we simplifying? The simplification work has to come from those closest to the problems — most leaders don't know half of what people are actually doing. Innovation Belongs to Everyone — Not a Lab "Psychological safety — it's not even a prefrontal cortex thing, it's not a conscious thought, it's that fight-or-flight reaction you have in the moment."   Phil makes the case that innovation starts with psychological safety at the team level, not an organization-wide mandate. It's the team leader asking questions, being humble, responding to disagreement with "tell me more" instead of "I don't agree." It means celebrating intelligent failures — someone who tested a hypothesis, found it didn't work, and stopped. At Amazon town halls, executives open by making fun of Amazon's failures, like the Fire Phone. The message: if you're thinking big, you'll also fail. The Fire Phone didn't work, but it informed future hardware investments. The only true failure is not learning from experimentation. Phil and Jana both emphasize that once leaders experience what happens when people are truly freed to do their best work, they get addicted to it. About Phil Le-Brun and Dr. Jana Werner Phil Le-Brun is the former International CIO of McDonald's and now leads the AWS Executives in Residence team, advising Fortune 500 leaders on transformation. Dr. Jana Werner is an Executive in Residence at AWS who built their EMEA transformation practice after leading digital change in financial services. Together they wrote The Octopus Organization: A Guide to Thriving in a World of Continuous Transformation (HBR Press).   You can link with Phil Le-Brun on LinkedIn and Jana Werner on LinkedIn.   Book site: theoctopusorganization.com Book on Amazon: The Octopus Organization

300 years after the publication of Jonathan Swift's Gulliver's Travels, Matthew Sweet looks at satire, past and present. How can satirists reflect critically and humorously on political events in an age of social media saturation and at a time when reality can seem stranger than fiction?He is joined by:Andrew Hunter Murray, comedian, writer and host of Radio 4's The Naked Week. His new book is Bad Deeds.Jan Ravens, actor and impressionist, known for her work on Spitting Image and Radio 4's Dead RingersRosie Holt, actor and comedian. Rosie's shows Churchill's Urinal and Rosie Holt: The Illegal Aliens have landed! will both be at Edinburgh Festival.Tom Peck, Parliamentary sketch writer for The TimesandSiôn Parkinson, artist, Research Associate at the Royal Botanic Garden Edinburgh and 2026 AHRC/BBC New Generation Thinker.Producer: Eliane Glaser

On this episode of skucast, Kara Parkinson, commonsku's SVP of Marketing and a veteran of Apple, Intuit, Nestlé, and PepsiCo, shares the creative brief she's drafting for merch buyers, the difference between category thinking and context thinking, and what makes a distributor pitch land with a CMO.

What if Parkinson's disease is more than a movement disorder? In this episode, I sit down with Dr. Greg Eckel, naturopathic physician and pioneer in neurodegenerative medicine, to explore a broader, root-cause approach to Parkinson's disease. Inspired by his late wife's battle with Creutzfeldt-Jakob Disease, Dr. Eckel shares the personal journey that led him to dedicate his career to understanding the underlying drivers of neurodegeneration. Together, we discuss the three major contributors he believes are central to neurological decline: environmental toxins, trauma, and infections. We also explore the role of gut health, alpha-synuclein, the vagus nerve, advanced diagnostic testing, personalized medicine, and emerging therapies such as non-thermal low-level laser therapy. This conversation challenges conventional thinking and offers a more comprehensive framework for understanding Parkinson's and supporting long-term brain health. If you're interested in the future of neurodegenerative care, the gut-brain connection, and strategies that go beyond symptom management, this episode is a must-listen.   Key takeaways: Three Buckets of Neurodegeneration: The holistic Echo Protocol examines environmental toxins, trauma, and infections as core contributors to Parkinson's and other neurodegenerative diseases. Diagnostic Innovations: Comprehensive diagnostic testing surpasses basic clinical exams by delving into hormonal levels, gut microbiome health, and possible toxic exposures. Holistic Treatments and Protocols: Utilize personalized supplements, dietary modifications, and non-invasive therapies like low-level laser to improve patient outcomes significantly. Innovative Approaches to Parkinson's: Dr. Eckel's Echo Protocol emphasizes neuroinflammation and synucleopathetic disorders, pushing the conversation beyond conventional categorizations. Community and Support: Building supportive communities and encouraging ongoing education empowers patients and practitioners to harness new insights and treatments for neurological conditions.   More About Dr. Greg Eckel: Dr. Greg Eckel is a naturopathic physician and Chinese medicine practitioner with more than 25 years of clinical experience and a deep focus on helping the brain do what conventional care often says it cannot: repair, reorganize, and recover capacity. After the death of his wife, Sarieah, from Creutzfeldt-Jakob disease, Dr. Eckel began asking a question that changed the direction of his work: What if the brain's capacity to heal is far greater than the medical system has been willing to acknowledge? That question led him into frequency medicine, quantum biology, mitochondrial metabolism, regenerative therapeutics, and root-cause neurological care. Today, his work spans Parkinson's disease, traumatic brain injury, neurodegeneration, cognitive decline, and normal brain optimization for people who want to protect, sharpen, and extend the function of the brain they rely on every day. He is the founder of bVital in Park City, Utah, the creator of the Eckel Protocol®, and the architect of the Brain Regen program. His clinical model begins by detecting the hidden drivers of dysfunction, correcting the conditions that block recovery, and helping patients build the resilience to thrive for years to come. A speaker, researcher, and author, Dr. Eckel has published peer-reviewed work, trained physicians nationwide, served as past president of the Oregon Board of Naturopathic Medicine, and reached over one million people through summits, webinars, and media appearances. His work continues from one conviction: your brain wants to heal. Sometimes it just needs the right conditions to remember how. Website Instagram Connect with me! Website Instagram Facebook YouTube  

Could eating late at night be hurting your gut health? Are prebiotic and probiotic sodas actually good for your microbiome? And what do GLP-1 weight loss drugs such as Ozempic and Wegovy mean for digestion, constipation, and gut bacteria? Dr. Will Bulsiewicz joins Chuck Carroll on The Exam Room Podcast to answer the most Googled gut health questions from listeners.

Multiple system atrophy is a rapidly progressive neurodegenerative condition that is often misdiagnosed as Parkinson's disease but carries a far grimmer prognosis. MSA has a median survival of just seven to eight years after symptom onset. Toxic aggregates of alpha‑synuclein and excess brain iron create a vicious cycle of neuronal damage that drives the multisystem motor and autonomic decline characteristic of the disease. Alterity Therapeutics is developing an oral, brain‑penetrant therapy designed to redistribute excess iron, reduce alpha‑synuclein aggregation and oxidative injury, and ultimately slow disease progression. David Stamler, CEO of Alterity, discusses the biology of MSA, the company's promising clinical results to date, and why this therapeutic approach may also have application in other neurodegenerative diseases.

Nicotine use is rising in young people Nicotine use among youth and young adults is rising according to the Centers for Disease Control with nicotine pouch use by people under 21 nearly quadrupling from 2022 to 2025. Nicotine is the highly addictive chemical stimulant found in tobacco. In 2024, almost 8% of high schoolers said they had used an e-cigarette in the past month, and more than 2% had used nicotine pouches. Some place the rise in use on health influencers on social media, who say nicotine has natural benefits such as better focus or claim it can prevent Parkinson's and Alzheimer's disease. Others say nicotine is a better alternative to smoking tobacco, since its non-carcinogenic and comes in fun flavors like mint and now fruit, approved by the Food and Drug Administration last month. Even U.S. Health and Human Services director Robert F. Kennedy Jr. said last year that nicotine pouches are "probably the safest way to consume nicotine." But is there any safe way to consume nicotine? Many health experts are concerned about this reframing, and its impact on young people. On Thursday's "Sound of Ideas," we'll ask local public health officials about this trend and ask about the role of nicotine on our health. Guests:- David Margolius, M.D., Public Health Director, City of Cleveland- Erika Trapl, Ph.D., Behavioral Epidemiologist & Professor, Case Western Reserve University- Wendy Hyde, Ohio Regional Director, Preventing Tobacco Addiction Foundation/Tobacco21 & Assistant Professor, Baldwin Wallace University- Ernest Williams, Barber, Polished Professionals & Graduate, Freedom From Smoking The Menu: Food Trucks Summer is underway, and communities are coming together for neighborhood celebrations, outdoor events and local festivals. Food trucks have become a staple of many of those gatherings, offering everything from regional favorites to inventive new flavors. We'll take a closer look at Northeast Ohio's food truck scene and its growing popularity. This is the latest installment of The Menu, our biweekly segment all about Northeast Ohio food produced in partnership with Cleveland Magazine. Guests:- Matt Maroon, Owner, Happy Camper Bar Car- Isabella Sugar, Managing Partner, CLE Chicken Food Truck & Catering- Delicia Dixon, Owner, The Urban Wrap Co.- Daniel Subwick, Director, Parks and Recreation, City of South Euclid

Why do two people with Parkinson's experience the disease so differently?In this episode, we sit down with researchers Patrik Verstreken and Natalie Kaempf to explore groundbreaking work that may help answer that question. Using advanced biology, biomarkers, and artificial intelligence, their team has identified what could be five distinct biological subtypes of Parkinson's disease.We discuss what these findings mean for people living with Parkinson's today, how genetics and environmental factors may influence disease progression, and why understanding the biology behind Parkinson's could lead to more personalized treatments, better clinical trials, and earlier diagnosis in the future.Chapters00:00 Introduction to Parkinson's Disease Research02:54 Understanding the Variability of Parkinson's Disease06:07 Symptomatic Treatments vs. Underlying Causes08:57 Subtypes of Parkinson's Disease11:51 The Role of Biomarkers in Early Diagnosis14:46 AI's Impact on Parkinson's Research18:10 Clinical Trials and Treatment Stratification20:59 Future Directions in Parkinson's Disease Treatment23:55 The Importance of Community and Hope

Parkinson's isn't easy to diagnose — everyone's symptoms differ based on their individual biology, leading to delays in diagnosis and treatment. One of The Michael J. Fox Foundation's (MJFF) key areas of focus is finding ways to diagnose Parkinson's disease earlier and more clearly, which could one day lead to more personalized treatments that can improve quality of life.Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0There are so many ways to get involved in the research that is leading to clearer disease diagnosis. Learn more about your role in research at: https://www.michaeljfox.org/your-role-parkinsons-researchThe Foundation's landmark study, the Parkinson's Precision Medicine Initiative, also known as PPMI, is recruiting volunteers. Join the study that's changing everything at michaeljfox.org/podcast-ppmiMentioned in this episode:Researchers are studying the link between sense of smell and brain health. People with and without Parkinson's can help by taking a scratch-and-sniff test. It's free, mailed to your home and takes just 15 minutes to complete. mysmelltest.org/getstarted

Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. The landscape of these industries is one of constant evolution, characterized by scientific advancements, strategic mergers, and regulatory maneuvers that shape the future of healthcare. In a significant scientific breakthrough, Merck & Co. and Gilead Sciences have made strides in HIV treatment with the development of a weekly pill. This innovative regimen combines Merck's islatravir with Gilead's lenacapavir, showing promise in two phase 3 trials. If approved, this long-acting oral therapy could revolutionize HIV care by offering a more convenient dosing schedule, potentially improving patient adherence and outcomes substantially. This novel regimen signifies progress towards simplifying HIV treatments with once-weekly dosing. Meanwhile, in the oncology sector, Gilead's Trodelvy faced challenges when combined with Merck's Keytruda as a first-line treatment for PD-L1-high non-small cell lung cancer. The phase 3 EVOKE-03 trial was terminated, shifting attention to competitors like AstraZeneca and Daiichi Sankyo, who continue to advance their own therapies in this area. In a strategic move to bolster its position in lung cancer treatment, GlaxoSmithKline (GSK) is acquiring Nuvalent for $10.6 billion, aiming to secure near-approval cancer therapies capable of challenging market leaders like Roche and Pfizer. This acquisition underscores the focus on targeted cancer therapies that increase treatment efficacy by honing in on specific genetic markers. Nuvalent's innovative pipeline of small molecule inhibitors targets drug resistance and mutations in cancer treatment—a strategic addition to GSK's portfolio aimed at enhancing its position amidst rapid advancements and intense competition in oncology. In diabetes and obesity management, Eli Lilly is advancing with its new oral GLP-1 receptor agonist, Foundayo (orforglipron), which has shown competitive efficacy over oral semaglutide. Analysts see Lilly's progress as strengthening its leadership in the growing obesity drug market. Similarly, AstraZeneca is making progress with its own GLP-1 candidate, elecoglipron, as phase 2 data sets the stage for pivotal studies. Promising clinical trial data from Eli Lilly's retatrutide for obesity-related conditions and AstraZeneca's elecoglipron suggest a strengthening pipeline for GLP-1 receptor agonists known for their dual effects on weight management and glycemic control. On the diagnostics front, Roche reaffirms its €600 million investment in Germany amid industry retrenchments by companies like Eli Lilly and Boehringer Ingelheim. However, Roche remains cautious about future risks due to shifting economic conditions. The financial dynamics within biotech are also noteworthy. Parabilis Medicines is planning a potentially record-setting IPO following Kailera Therapeutics' successful public offering earlier this year. These trends indicate strong investor confidence and an influx of funding towards innovative cancer therapies. Meanwhile, CeQur's $100 million Series E funding round aims at accelerating insulin patch delivery systems' commercial growth—highlighting ongoing innovation in diabetes management solutions. Regulatory updates reveal AstraZeneca facing reprimands from the UK marketing watchdog due to repeated breaches related to LinkedIn activities—an ongoing challenge in pharmaceutical marketing compliance. The integration of digital health solutions continues apace as ixlayer partners with Vertex Pharmaceuticals to launch a digital acute pain management platform. This initiative aims at improving patient care by reducing reliance on opioid-based treatments. These developments paint a picture of an industry where scientific innovations, regulatory hurdles, and technological advancements intersect to shape future therapeutic landscapes. Precision oncology is another area witnessing substantial growth. The landscape also sees notable activity in rare disease therapeutics. Johnson & Johnson's Talvey has gained acceptance in Scotland for treating relapsed multiple myeloma using bispecific antibody technology—a trend toward leveraging immune system targeting technologies to enhance cancer treatment efficacy. Moreover, Zai Lab's Tivdak received approval from China's NMPA for cervical cancer treatment based on Phase 3 data, highlighting the rise of antibody-drug conjugates (ADCs) as potent oncology therapies due to their targeted delivery mechanisms. On the research collaboration front, AlzeCure Pharma's partnership with Eli Lilly focuses on Alzheimer's disease research through Alzstatin ACD680—a small molecule targeting neurodegenerative pathways—a testament to the collaborative efforts needed to tackle complex diseases like Alzheimer's. However, challenges persist as Bial discontinued its GCase activator program after failing Phase 2b trials for Parkinson's patients with GBA1 variants—a stark reminder of the high-risk nature inherent in drug development despite initial promise. These myriad developments underscore a vibrant period within pharmaceutical and biotech sectors where scientific advancements rapidly translate into actionable therapies promising substantial improvements in patient care by addressing unmet medical needs globally.Support the show

We don't usually have repeat guests on this podcast… except we're making an exception for the wonderful and wise Alan Alda. Alan Alda, of course, is an award-winning actor, writer, director, and podcast host. You probably know and love him as Hawkeye on M*A*S*H or Senator Arnie Vinick on The West Wing. He is endlessly curious on just about every topic—which makes him the perfect person to talk to about empathy, learning across differences (and disagreement), and how we might age into new hobbies and careers.  In this conversation, Alan and Kate discuss:   Tricks for staying curious as we age How to talk to someone you disagree with How Alan hopes to destigmatize Parkinson's Disease The difference between empathy and compassion and how to practice these important skills This episode originally aired March 2024.

Live June 8, 2026 | Yaron Brook Show(Season 12, Episode 100)Israel/Iran/Lebanon/Trump; Russia; Interview; H1B; N. Korea; Achievements | Yaron Brook ShowIsrael vs. Iran: Is Trump Saving Hezbollah, Betraying Israel, and Rewriting Reality?Plus: Russia's grinding war, the H-1B battle, North Korea's weapons boom, and the technological breakthroughs changing the future.Israel strikes. Iran retaliates. Hezbollah refuses to disappear. And Donald Trump inserts himself into the center of the Middle East's most dangerous conflict.In this episode of The Yaron Brook Show, Yaron returns to break down a dramatic weekend in the Middle East, the escalating Israel-Iran-Hezbollah confrontation, Trump's pressure campaign on Israel, and what the conflict reveals about America's role in the region.But that's only the beginning.Yaron also examines the state of Russia's war in Ukraine, Trump's latest claims about January 6 and the 2020 election, the growing fight over H-1B visas and legal immigration, North Korea's surprising economic gains from arms sales, and several astonishing technological breakthroughs—from autonomous trucking and Parkinson's treatments to supersonic flight.Then, in a wide-ranging Q&A, Yaron tackles everything from Neil deGrasse Tyson and Kant to Elon Musk, altruism, capitalism, immigration, gun rights, Netanyahu, Hezbollah, and the future of Objectivism.Whether you agree or disagree, this episode pulls no punches.Watch now and join the conversation.

Morning Show 06-09-26 Hour 3 Robert Parkinson, Declaration of Independence by The Watchdog

Discover 5 key autoimmune triggers hiding in your past. From COVID and herpes simplex to staph, Epstein-Barr, and strep infections, Nurse Doza breaks down how past infections can reprogram your immune system to attack your own tissue — and what gut health has to do with it all. Gut (L-Glutamine) by MSW Nutrition Gut, featuring 4 grams of pure L-Glutamine per scoop, is the primary fuel source for the cells that line your intestinal wall. When past infections, antibiotics, or chronic stress compromise your gut barrier, your immune system loses its most important line of defense — creating the conditions where autoimmune triggers thrive. Gut helps repair the gut lining, reduce digestive inflammation, and support the immune cells that depend on a healthy gut to function properly. Whether you're managing an existing autoimmune disorder or working to prevent one, healing your gut is where it starts.

Text your thoughts and questions!Have you ever sat down to write an email, finish a report, or tackle a simple task, only to watch it consume far more time than it should have? It can feel frustrating, especially when you thought having extra time would make things easier. But what if more time is actually part of the problem?The idea behind Parkinson's Law is surprisingly simple: work expands to fill the time available for its completion. What started as a satirical observation in the 1950s has since been supported by research showing that when people are given more time than they need, they tend to use it, whether the task requires it or not.In this episode, we're exploring why open-ended time can lead to procrastination, overthinking, perfectionism, and unnecessary task expansion. More importantly, you'll learn how to use intentional time constraints to your advantage so you can focus better, make progress faster, and create a more sustainable approach to productivity that works with your brain instead of against it.This week, episode 317 of the Positively Living® Podcast explores the practical side of Parkinson's Law and shares simple ways to use time boundaries, self-created deadlines, and focused work sessions to accomplish more without rushing or burning out.Key Takeaways:Understand how Parkinson's Law causes tasks to expand simply because more time is available.Recognize why open-ended projects often lead to procrastination, overthinking, and perfectionism.Learn why urgency and deadlines can dramatically improve focus, especially for ADHD brains.Use timeboxing to create clear boundaries that help your brain stay engaged and productive.Define what "done" looks like before you begin to avoid endless tweaking and refinement.Create meaningful self-imposed deadlines when external deadlines don't exist.Improve focus and consistency by working in shorter, intentional sprints instead of marathon sessions.Develop the self-awareness to recognize when a task genuinely needs more time versus when it's simply expanding to fill available space.Thank you for listening! If you enjoyed this episode, take a screenshot of the episode to post in your stories and tag me!  And don't forget to follow, rate, and review the podcast and tell me your key takeaways!Learn more about Positively LivingⓇ and Lisa at https://positivelyproductive.com/podcast/Stop trying to fit into someone else's productivity rules! Grab my free Productivity Toolkit, a collection of workbooks designed to help you explore how you work, uncover what truly matters to you, and create your very own energy-friendly systems. Get it here: www.positivelyproductive.com/plpkitCONNECT WITH LISA ZAWROTNY:FacebookInstagramResourcesWork with Lisa! LINKS MENTIONED IN THIS EPISODE:Solo Episode PlaylistBook a Clarity CallAsync Coaching(Find links to books/gear on the Positively Productive Resources Page.)Dance Song Playlist V1, V2, V3Music by Ian and Jeff ZawrotnyStart your own podcast with Buzzsprout!The Self-Care to Wellness Bundle is available for 1 week only - from July 9th - July 16th

This week on Perfectly Twisted, we're joined by Dr. Yi Song, author, speaker, and founder of a wellness retreat center who blends Eastern and Western medicine to help people optimize their health and longevity. Dr. Song breaks down the science behind stem cells and their potential applications for everything from pain relief and Parkinson's disease to anti-aging and regenerative medicine. She also explains what stem cell treatments are currently legal in the United States, how hormone balance can be supported through food, and the supplement mistakes many people make. Most importantly, she shares her philosophy on prevention, wellness, and why happiness may be one of the most powerful tools we have for living a longer, healthier life. #stemcelltherapy #RegenerativeMedicine   #HormoneHealth   #EasternMeetsWesternMedicine   #HealthyLiving  Find us here: Website - Perfectly Twisted Podcast • Perfectly Twisted with Nicole Eggert Mail- perfectlytwistedpod@gmail.com  Instagram - https://www.instagram.com/perfectlytwistedpodcast?igsh=YnA4NHgxMzZ4ZW56&utm_source=qr Facebook - https://www.facebook.com/profile.php?id=100090942948174&mibextid=wwXIfr Youtube - https://youtube.com/playlist?list=PLAWfs4D4mkD8mzumFj0jZrOAEHu-aOVwd&si=j8JP1R7pAQQ1xOPR Hurrdat Media - Hurrdat Entertainment | Hurrdat Media Learn more about your ad choices. Visit megaphone.fm/adchoices

Why This Episode MattersFirgun Ventures launched in late 2025 with a $70M first close anchored by the Qatar Investment Authority and a mandate that doesn't exist anywhere else in the market: lead Series A and B rounds in quantum scale-ups globally. Kris Naudts is a neuroscientist and former Culture Trip founder whose path to quantum runs through a near-fatal medical misdiagnosis. Zeynep Koruturk spent over a decade building the Goldman Sachs Tech Initiative and meeting more than a thousand founders. Both were early angels in what became Quantinuum.If you're trying to understand how quantum companies actually get financed between the lab and the IPO window — or why a specialist fund needed to exist at all — this conversation is one of the clearest views available. It's also a useful frame for founders thinking about what an informed institutional investor actually does in a round.SponsorThis episode is brought to you by Outshift, Cisco's incubation engine. The need for computational power is rapidly increasing in every sector. From drug discovery to material innovation to complex financial modeling, classical systems are reaching their absolute limits. It's time for a paradigm shift. The answer is a scalable quantum network, built on open standards and vendor-agnostic architecture. By uniting distributed quantum devices, you unlock limitless computational power.Learn more about the Cisco Universal Quantum Switch at Outshift.com.Go deeper with the blog post The switch that quantum networking has been waiting for.What We Get IntoWhy Kris's ALS misdiagnosis became the conviction event that pulled him from media entrepreneurship into quantum investingHow Zeynep's decade at Goldman Sachs Tech Initiative shaped her pattern-matching for deep tech, and where that pattern-matching breaks down in quantumThe structural reason Series A/B is the real bottleneck in quantum financing — and why precede and seed capital is no longer the gap people assume it isHow Firgun underwrites engineering and execution risk after the scientific risk is largely retiredWhy a quantum-specialist fund unlocks soft commitments from larger institutions that otherwise stay on the sidelinesThe role of Firgun's "scientific co-founder" Professor Mete Atatüre and the need for sub-specialist diligence across modalitiesHow Firgun thinks about portfolio construction across silicon-spin/photonic (Photonic Inc.), silicon CMOS (Quantum Motion), and other architectures without picking a qubit winnerWhy a truly global mandate is a feature, not a focus problem, given how concentrated quantum talent is in roughly a dozen ecosystemsHow sovereign capital, US equity-stake announcements, and geopolitical fragmentation are starting to reshape who can invest in whatWhy the binary "fault-tolerant or bust" framing of quantum investing misses the gradient of capability that drives near-term valueResources & LinksGuest & FirmFirgun Ventures — The fund's homepage, with the team and "Time to Talk Quantum" podcast featuring the founders' own framing of the market.Firgun Ventures on Crunchbase — Confirms London HQ, global mandate, and Series A/B focus.Fund Launch & ThesisFirgun Ventures Launches $250M VC Fund to Invest in Quantum — The Quantum Insider — Launch details, QIA anchor commitment, and founder backgrounds.Firgun Ventures Launches With $70M for Quantum Tech Innovation — TechFundingNews — Deeper breakdown of the LP roster and market rationale.Firgun Ventures: Scaling Quantum Beyond the Early Stages — Future of Computing — Extended interview with Kris and Zeynep on the Series A/B bottleneck.Portfolio Companies MentionedFirgun Invests in Photonic Inc. — The Quantum Insider — Firgun's first portfolio investment in DARPA-validated Photonic Inc.Photonic Inc.'s World-First Quantum Teleportation — QC Report — Technical context on the "Entanglement First" silicon-spin/photonic architecture.Photonic Inc. Closes $200M+ Round — The Quantum Insider — Final close at a $2B valuation.Quantum Motion Raises $160M Series C — The Quantum Insider — Firgun's first European investment in silicon CMOS quantum computing.Quantum Motion's Silicon CMOS Approach — Technologies.org — Technical analysis of the CMOS scalability thesis.Key Quotes & InsightsKris on the conviction event: "If you're expecting to die and then you're told you're going to live, you have to rethink it yet again… You can go in the direction of enjoy every day, or you can go in the direction of let's try to do something meaningful with whatever time I have left."Zeynep on the real bottleneck: Pre-seed and seed capital in quantum is no longer the gap — the A and B rounds are. Roughly 40% of companies in the space need that bridge to unlock larger institutional capital, and almost no one is set up to lead it.Kris on diligence limits: No one person can underwrite the full quantum stack. Firgun pairs a "scientific co-founder" with sub-specialists for each modality, because in quantum "no propositions sound stupid" — and that's exactly the problem.Zeynep on the asymmetric bet: Quantum is one of the few areas where geopolitical reality creates a floor under the downside. The West can't afford to lose, which means funding will be there long enough for the right companies to mature.Kris on willing the timeline: "You cannot will it into being. The space will evolve at the pace it is set to evolve with the capital and the talent in it." A useful corrective for anyone pitching a five-year cure-for-Parkinson's roadmap.Related Episodes

Dr. Connie Marras discusses with Dr. Sara Schaefer her recent study in Movement Disorders Clinical Practice exploring the perspective of Persons with Parkinson's disease on the definition of quality of life. Read the article.

CarneyShow 06.08.26 Dani Wexelman, Robert G Parkinson, Rob Silverstein, Jordana Miller by

The BBC Radio 4 investigative programme 'Impulsive' shocked listeners across the world. Aired at the beginning of the year, 'Impulsive' revealed the devastating effects that the readily prescribed Parkinson's drugs, dopamine agonists, were having on their users, including causing hypersexuality and compulsive gambling, among other extremes. We've actually covered this topic before on Movers & Shakers, but the Radio 4 show brought the discussion back to light, so this week we're readdressing the risks associated with these drugs and what is being done to tackle them. The presenter of 'Impulsive', BBC Investigations correspondent Noel Titheradge, joined us, alongside one of the show's interviewees, and the co-founder of the Dopamine Agonist Action Group, Freddie Waite, to explain their journey to uncovering this 'shadow world'.Find out more about the Dopamine Agonist Action Group at www.impulsive.worldMovers & Shakers is brought to you in partnership with Cure Parkinson's.Presented by Rory Cellan-Jones, Gillian Lacey-Solymar, Mark Mardell, Paul Mayhew-Archer, Sir Nicholas Mostyn and Jeremy Paxman.Produced and edited by Nick Hilton for Podot.Associate Producer: Lulu Goad & Ewan CameronMusic by Alex Stobbs Hosted on Acast. See acast.com/privacy for more information.

Send us Fan MailWe talk about how high standards and perfectionism can freeze momentum, especially when you are building something big like a new website. We share a practical way to choose a deadline, define a baseline, and ship a first version that helps people find you and pay you. • why big ideas turn into start stop progress • how Parkinson's law makes long deadlines drag • choosing a baseline so version one can go live • simple website essentials for artists, makers and shop owners • taking tiny daily steps to build momentum • when paying for better tools or help saves time Let me know if you need some help around this. You find all the information on paternshift.fm. Share this podcast with someone you know that you think could benefit from some insights.Support the show☆ other ways to SUPPORT THE SHOW ☆If you appreciate the free content and the work we put into this podcast, consider showing your support in a way that feels right to you. This could be by sharing episodes with friends, signing up for our newsletter, or making a small monthly contribution by clicking the Support the Show link. Your support keeps the podcast going and aligns with the values we share. Thank you for being a part of this movement!☞ GET MAIL ☜☆ SIGN UP HERE! ☆☞ FIND OTHER BUSINESS OWNERS IN OUR COMMUNITY SPACE ☜☆JOIN THE CONVERSATION☆Have a question? Want to offer your opinion? Do you have an idea for a guest or topic? info@ja-wol.com or leave me a voice message!

Is your morning cup of coffee doing you more good than you think? In this episode of Mini Medical School, we dig into the science behind one of the world's most popular beverages — and the answer might just make you feel great about your habit. We cover the chemistry of coffee — from chlorogenic acids and trigonelline to caffeine, mycotoxins, and why what you put in your cup matters as much as the coffee itself. Then we head to mini medical school to learn how caffeine actually works in the brain, why adenosine is the real story behind your morning grogginess, and what the latest research says about coffee's surprising health benefits. In this episode: How caffeine blocks adenosine — and why that keeps you awake Coffee and brain health: Alzheimer's, Parkinson's, and mood Heart, liver, kidney, and metabolic benefits of regular coffee drinking Who should be cautious — and what the risks actually are The truth about decaf, pregnancy limits, and daily intake guidelines Why the answer to "is coffee good for you?" is more personal than you think Whether you're a gulper or a sipper, black or blended, this episode will give you evidence-based answers — and maybe a little peace of mind. 0:00 – Introduction 1:45 – Mini Medical School: Coffee Chemistry 4:08 – Caffeine & How It Works 6:25 – Benefits of Coffee 9:42 – Risks of Coffee 10:29 – Decaf & Withdrawal 11:40 – Conclusion

Dr. Deb Muth 00:08What if the toxins in your food and water weren’t just harming our bodies, but rewriting the very code of human health? My guest today, MIT scientist Dr. Stephanie Sineff, has spent over a decade connecting the dots between environmental toxins, metabolic chaos, and neurological decline. You’ll want to hear every word of this conversation. You guys can put our, Serenity ad in here, and then I’ll do the standard intro.Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, explore cutting-edge regenerative medicine, and empower you with the tools to heal. I’m Dr. Deb, your medical detective.And today, we’re diving into how environmental toxins and nutritional imbalances are silently shaping chronic disease patterns, from autoimmune disorders to neurodegenerative decline. And how we can take back control of our health. So, as usual, grab your cup of coffee, tea, or whatever helps you unwind, settle in, and let’s get started on your journey to deeper healing. So, Dr. Sunif, so glad to have you here. I can’t wait to have this conversation with you. We were just chatting off-camera a few seconds ago about what we’re going to chat about, but tell us a little bit about your background and how you got into this field of looking at toxins and mitochondria. Seneff 01:50Okay, yeah, my background is a bit eclectic, so it starts out with biology. I have an undergraduate degree in biology from MIT. My PhD is in electrical engineering and computer science, so that’s quite a switchover. And most of my career, I was writing computer code to train computers to talk to humans in a natural conversation… conversational interaction with computers. We were pioneers in that space. You can see that it has really taken off now. And actually, by 2006, 2007, I started to realize that the kind of work I did already then was getting compromised by the, by the emergence of AI. And I got concerned that, I wouldn’t be able to sustain the path I was on. And it’s happening now, of course, to the young… many people, young people today, are facing a crisis in computer science, because it used to be if you had skills in hacking code, you were good to go, you know, and that’s just not true anymore, so that’s another whole story, but anyway, I decided I needed to do something different, and I pivoted in a big way in 2007. managed to get the company that had been funding me, a Taiwanese company called Quanta Computers, And they,We’re willing to switch over to funding me to do research on health and toxic chemical exposures. Which was a miracle that they let… they let me switch over to that, and that was fantastic, 2007. So it’s been almost 20 years. that I’ve been looking for toxic chemical exposures and their association with human disease. And I focused initially on autism and heart disease, kind of for personal reasons, because I knew people who had, you know, who had those issues.But it led into a much, much bigger story, and I’m super excited about what’s happened over the last 20 years. It’s been a continual learning experience for me, and I’ve just kept broadening my space in biology, furiously reading papers as I discovered new concepts and trying to explore those. opening up new windows, and it’s just been a profusion of learning over the past 20 years, and I’ve published many papers at this point. Peer-reviewed papers on the topics of toxic chemical exposures and disease. Particularly, glyphosate is the one I really focused on, and I wrote the book, Toxic Legacy, how the weed killer glyphosate is Destroying Our Health and the Environment.That was published in 2021. So. Dr. Deb Muth 04:18So I’m sure you have a few thoughts about the administration wanting to bring that back to be made at home instead of China, right? Seneff 04:26I know, that’s so interesting. And actually, you know, he makes a point that I agree with, which is that we are relying on China. for importing a whole bunch of stuff that’s really toxic, and we’re pouring it all over our food supply, so China’s probably very happy to poison us, you know? Oh, absolutely. It’s kind of ironic that we’re doing that, and he makes a good point that we shouldn’t be relying on China for these chemicals that are poisoning us, but where he misses the point is he says, well, we just need to poison ourselves, you know? Rather than getting rid of that chemical, we need to really change the way we grow food.I think it’s the number one most important thing right now. in America is to change the way we grow food, and it has to be certified organic, regenerative. We need to focus on healing the soil, just as we have to heal the gut. I mean, we’ve really messed up the microbes in both the soil and the gut, and the consequences, as you can see, are a huge problem with human disease. Dr. Deb Muth 05:20They’re devastating. I mean, we have so much chronic illness and so much neurological disease these days, and just the rise of autism, it should be telling us that we’re doing something wrong, right? Seneff 05:31Absolutely. Dr. Deb Muth 05:32We have a problem. For those people who are listening that don’t understand what the term glyphosate is, can you explain that a little bit to them? Seneff 05:39Yeah, so it’s one of the many herbicides that we use. We use herbicides, fungicides, and insecticides in agriculture, all these poisons, and it kind of seems crazy to me that we would think it’s okay to pour poisons all over our food supply. I don’t understand why we think that’s fine.Yeah. You know, categorically. Glyphosate is supposed to be a wonderful chemical, because it’s an herbicide that kills all plants except for those that have been engineered to resist it. And supposedly is completely harmless to humans. And that’s what gets to be, you know, disbelief, because how can something so toxic to plants be harmless to humans? Just, how can it be? Dr. Deb Muth 06:14We haven’t been re-engineered like the seeds that they use from Monsanto, so how can it not affect us if it only affects everything but their seeds that they’ve modified to make grow beautifully under that condition? It doesn’t make any sense. Seneff 06:32Right, and of course, the critical thing they missed is that our gut microbes do have that pathway. It’s the chicken mate pathway that it disrupts. Really critical in all the plants, and in most of the microbes. In the soil and in the gut, and so it kills off the microbes as well as the plants, and when it kills off your gut microbes, you gotta watch out, because gut dysbiosis is a huge thing. And we’ve had so many papers coming out lately that Talking about the relationship between gut dysbiosis and all kinds of different diseases. Dr. Deb Muth 07:01Do you think that’s why we see so much gut dysbiosis these days? Seneff 07:04Oh, absolutely. I think it’s not just glyphosate, because we have lots of poisons that are messing up our gut microbes, but glyphosate is a really big one, because the shikimate pathway is essential for many of the microbes, and they use it to make essential nutrients for the host. So we get compromised as well, just because they can’t make those nutrients in that. Dr. Deb Muth 07:22It’s so… Seneff 07:22lies. Dr. Deb Muth 07:23so much harder today to treat people with gut issues than it was 25 years ago when I started. It was so much easier. And now, it’s, like, nearly impossible sometimes to get some of these people back to a good, healthy gut microbiome, no matter what you do, no matter how well they eat, and all the things that they do. It’s a struggle, for sure, compared to what it was 20 years ago. Seneff 07:44It’s interesting that you have that personal experience, because I think people like you really can see what’s happening. Dr. Deb Muth 07:49and appreciate. Seneff 07:50the difference between then and now. I, of course, as a child, autism was not something I knew about at all. Really, when I was a child. It didn’t exist, basically. I mean, it was so rare. And now, you know, everyone knows someone with autism, you know, pretty much. Dr. Deb Muth 08:08Autism and Parkinson’s and Alzheimer’s seems to be just so much commonplace. Everybody knows somebody in their family that is affected by one of those disorders, if not multiples, and We tend to say it’s genetic, right? Well, there’s got to be a genetic… why wasn’t it genetic 50 years ago, or 100 years ago? But now, all of a sudden, it’s so prevalent in our environment that we’ve just become acceptable of it, and I think that’s wrong for us to do that. We shouldn’t be doing that. Seneff 08:38I know. I find it very interesting how quickly it appears that humans adapt to the new normal, you know? Dr. Deb Muth 08:44Yeah. Seneff 08:45It’s normal that you have, you know. 3% of the kids have autism, that’s normal, you know? It’s just like, no, it’s not. And also, of course, all the Alzheimer’s and dementia and Parkinson’s, as you mentioned, in the elderly, those are connected, because they’re all related to brain problems that are being caused by chemicals that are destroying the brain. Dr. Deb Muth 09:03Yeah. So, how does glyphosphate interact with our body’s ability to absorb those essential nutrients, like sulfur? Seneff 09:12Yeah, well, it’s… that’s a big… that’s a big question. I don’t know where to begin with that one. Glyphosate, you know, it’s a train wreck for the gut microbes, and then that causes the gut dysbiosis. The microbes are unable to produce adequate amounts of nutrients that are essential for the host. And as a consequence, the host cells get sick, you know, so the colonocytes get sick because they’re not getting adequate nutrition. Because the microbes can’t produce the nutrition they normally would produce. I think that’s a good summary of what’s going on. You get inflammation in the gut.And then the inflammation causes immune reactions, so you get the immune cells coming in, and they create inflammation, you know, it’s just like there’s a kind of a festering going on in there that’s really a train wreck for the whole system. Dr. Deb Muth 09:58Do we see different, results with things like this in Europe, where they’re not allowed to use a lot of these chemicals that we’re allowed to use here? Seneff 10:07Yeah, they are allowed, but it’s much, much less there. My friend, Tony Mitra got his government, Canada, to do a test… to do a big test of over 8,000 samples, food samples, to get… look for glyphosate. U.S. government doesn’t bother to test for glyphosate, because they consider it to be safe.We know it’s all over our food supply from work by people like Zen Honeycutt. My friend Zan Honeycutt of Moms Across America has really been on a mission to test all kinds of different food samples for glyphosate and finding it extensive in our food supply, in the school lunches. in the fast food restaurants and the food that’s fed to the Army. She’s done all these different studies, breast milk. Wines, you know, all the wines were contaminated, even the biodynamic, which are organic.Had small amounts of glyphosate, so it’s just like it’s all over the food supply. Canada did 8,000 samples. Tony Beecher finally got them to do that after many years of harassing them, and then he published the results in a book called Poison Foods of North America, because they found that they had imports from Europe, imports from Mexico, imports from the U.S, And basically, the U.S. and Canada came out way on top, as far as overall, the numbers were much higher in those two countries. And Mexico lined up with Europe, which was quite interesting to me. So, you know, you’re better off if you buy food from Mexico. Dr. Deb Muth 11:31Yeah, and I wouldn’t have thought that, I would have thought that was different. Seneff 11:34And I know you often think that Mexican food is not going to be as carefully regulated, and you might get some kind of, toxin. You don’t expect Mexican food to be healthier than American, but it is. Dr. Deb Muth 11:44Yeah. Yeah, can you talk a little bit about deuterium? What is deuterium? Seneff 11:51Okay, that’s a good place to start. Yeah, deuterium… I am absolutely fascinated with deuterium, and I believe that the team of researchers that I’m working with, we are on to something really huge. I’m super, super excited. I almost can’t contain my excitement with this, because once we started looking, it’s just like everything made so much sense. Everything kind of came together. In terms of metabolism, and disruptive metabolism, and all the stuff that’s going on in the gut. It really, really makes sense. Deuterium is heavy hydrogen. It’s a natural element. Hydrogen is the smallest element, the upper left corner of the periodic table. One proton and one electron, and it’s by far the most common atom in the universe.And in our body, as well, by far the most common atom in our body, and it’s involved in all the chemical reactions that take place. And so, you know, have carbohydrates. The hydrates is hydrogen, you know, in the word carbon, hydrogen, carbohydrates. And of course, carbohydrates are, you know, basic foods. So anyway, deuterium has an extra neutron. It’s just like carbon-14, so carbon-12, carbon-14 is a little bit heavier. It’s got 14 instead of 12. It has extra neutrons. So there are these kind of isotopes of various atoms, but hydrogen has hydrogen, deuterium, and tritium. Tritium has two extra neutrons. It’s very rare, and deuterium has one extra neutron, and it’s rare compared to hydrogen, but it’s not rare, because hydrogen’s so common. So it’s actually present in the blood at five times the level of calcium, for example. Dr. Deb Muth 13:24Oh. Seneff 13:25So it’s not rare, but it’s a very interesting atom that has caused us trouble in the mitochondria. Dr. Deb Muth 13:32Is it actually considered a toxin? Seneff 13:34It’s a natural element, you know. I mean, you have natural elements that are toxic, you know, like some of those metals, like mercury, for example, is a natural element, but it’s toxic, so it’s not a chemical, it’s not a chemical, you know, not made in the chemical lab. It’s just an atom. And it’s all over the universe. It’s not like you can avoid it, or you can, you know, you can’t get rid of it. It’s everywhere. And so it’s a natural part of biology, and our biology has evolved. to very, very clever ways to protect the mitochondria from deuterium. So the thing is, mitochondria have ATPase, which makes ATP, and ATP is the universal… it’s the energy source for the cell.ATP. It’s made in the mitochondria, very, very important, oxidative phosphorylation, you know, that’s sort of basic in biology. And, those ATPase pumps, depend upon hydrogen flowing through the pumps to generate, motor force to make the ATP.And they pile up the hydrogen inside an inner membrane space. They’re kind of cute. The mitochondria have this internal matrix in the hole, like a donut hole. The matrix is where a lot of activity is going on. And then there’s a membrane, but the membrane has both an outer membrane and an inner membrane. So there’s an intermembrane space where the mitochondria dump a lot of protons. They make… put lots and lots of protons in there, and then the protons naturally come out through basic… through basic physics, they come out, and the pumps are there to grab the energy as the protons come out. It’s quite cool. Go back into the matrix. the protons go back into the matrix. So what the body does is it tries to keep deuterons out of those… out of that intermembrane space. It tries really hard not to put deuterons in there. So deuterons are the equivalent of protons.You know, proteom is the normal hydrogen, and then deuterium is the… is the one with the extra neutron that makes it twice as heavy. So because it’s twice as heavy, it behaves very, very differently. It’s kind of like a big, bulky thing coming through the pumps, and it can clobber them. It can really mess them up.And the body knows that, and so the body has designed incredibly elegant mechanisms to keep the deuterium levels inside that inner membrane space as low as possible. the body obsesses on that. And once you realize that, all of a sudden, lots and lots of things make sense in terms of looking at biochemistry and what’s going on. All kinds of things that didn’t make sense before suddenly come. clear… clear… are motivated by this idea of avoiding deuterium in the inner membrane space. So it’s really, really fascinating biology. Dr. Deb Muth 16:08So does the glyphosate tend to increase the deuterium in that space, or does it disrupt it? Seneff 16:16It definitely increases it, and the reason why is because it disrupts the enzymes that manage it. And so, for example. So this, I have to get into hydrogen gas and microbial production of hydrogen gas, which is central to the story. And you know, people get gashy, they have, like, bloating and stuff, there’s a lot. Dr. Deb Muth 16:34echo. Seneff 16:34That’s because those gases that are being made by the microbes are unable to be brought back into organic matter. So normally the microbes make lots and lots of gas, and they start with hydrogen gas, and they make methane gas, they make hydrogen sulfide gas, and they make all these gases. And then they use those gases as reducing agents to come back and make organic matter. So they basically convert food into basic gases, like hydrogen and carbon dioxide, right? And then they take the carbon dioxide and hydrogen to convert it back into food. And the reason why they do that is because the process of making the gas tremendously strips out the deuterium. This is absolutely central, I think, to metabolism.And it’s not something very many people are aware of. The microbes make the hydrogen gas. And when they do that, they lose 80% of the deuterium, because the deuterium tends to stay in the aqueous space, because it’s too heavy. You just think of, you know, trying to lift out… if you’re twice as heavy, it’s a lot harder to get out of the liquid into the air. You know, so basically to make the gas. When you make the gas, you lose a lot of the deuterium. And that is super, super central, I think, to metabolism. Dr. Deb Muth 17:47So, if that’s what’s happening inside of there, it’s obviously creating metabolism issues. What does that mean for energy and mitochondrial health, then? Seneff 17:58Well, what happens is that the microbes are unable to make enough of those nutrients that are super for the host that have low deuterium. And a particular one that I have in mind is butyrate. And I don’t know if you know anything about butyrate. Dr. Deb Muth 18:10Yeah. Seneff 18:12But it’s a very healthy resource for the gut. The colonocytes lining the gut, 80% of their food is butyrate. They love butyrate, normally. But lots of people have butyrate deficiency in their gut. And that deficiency is due to the fact that the microbes can’t make the hydrogen gas, because when they make the hydro… or they can’t bring the hydrogen gas back in to make. Dr. Deb Muth 18:34Beautiful. Seneff 18:35Because a butyrate comes from the hydrogen gas that’s produced by the gut microbes. Dr. Deb Muth 18:39So, if we supplement with N-butyrate, does that help that process work better, or does it not really do much with the deuterium, then? Seneff 18:48Well, there’s a big question with supplements, and I’m really starting to appreciate this more. You know, I always like natural, right? Natural versus synthetic. And I think there’s a huge difference. For many of these supplements that are popular, there’s a huge difference between natural and synthetic. Yeah. And that big difference has to do with the level of deuterium, because if it’s made synthetically. It’s not going to be depleted in deuterium. So when you’re taking… and I don’t know butyrate, you have to go and look at how they manufacture it to see if it comes from natural or synthetic ingredients. It’s extremely interesting with… I’ve looked into some of these other nutrients that people like to take as supplements. Choline by tartrate is one that I really was fascinated with, because… and there are papers that show that if you take choline by tartrate as a supplement… so choline, of course, is a very important nutrient, a lot ofAre deficient, especially if they’re vegetarian. And choline bitartrate is a synthetic form of choline. And, choline bitartrate, if you take… the studies have shown There’s a beautiful study that had people who ate a bunch of eggs, you know, because eggs are high in choline, and then they had people who took choline by tartrate to get an equivalent amount of choline in their diet compared to the eggs, right? And the people who ate the eggs were fine, and the people who ate the choline bitartrate were not. They had a very big increase in a metabolite called trimethylamine oxide, TMAO. Dr. Deb Muth 20:13in the. Seneff 20:14in the blood. And TMAO is a risk factor for a huge number of diseases, you know, all the usual suspects, the diabetes, the cholesterol, the heart disease, cancer, all kinds of diseases. Dr. Deb Muth 20:26TMA over. Seneff 20:26is a very interesting molecule that’s been studied quite a bit recently. There’s a lot of papers on it. I don’t know if you’ve heard of it, TMAO . Dr. Deb Muth 20:32I have, yeah. Seneff 20:33Yeah, okay. Well, that one is a… it’s very, very interesting, and I have a paper that I’m trying to get published right now that I’m quite proud of that talks about all of this, but they found that when you eat the eggs and get the choline that way, you’re fine, but if you take the choline bichartrate, you’re not. You get all this TMAO. And the reason, I think, is because the microbes… the microbes make TMA from choline. the trimethylamine. Choline has a nitrogen atom with 3 methyls attached to it, and those methyls are going to be really low in deuterium. Because they’re part of the methylation pathway, which microbes make sure those methyls are low in deuterium. So all the whole methylation pathways, I think, is a distribution system to deliver low deuterium nutrients throughout the body, not just in the gut. You know, and the body has all these ways of hooking methyls onto things. Dr. Deb Muth 21:26and take it. Seneff 21:26them off, and when it takes them off, it metabolizes them in the mitochondria, delivering to them low deuterium nutrient. So, so when you take the choline bitartrate, and it’s not low deuterium, what happens is you end up with molecules of TMA, trimethylamine, that have deuterium in them. And when you have those, they won’t… the microbes won’t metabolize them, they won’t turn them back into hydrogen. You know, deuterium depleted hydrogen, they won’t do it. So they stick around, the TMA doesn’t get metabolized, and then it gets sent to the liver, the liver turns it into TMAO, and now you’ve got your problem. And I think TMAO is a marker for deuterium overload in the mitochondria, in the methylation pathways. Dr. Deb Muth 22:06That’s interesting that you’re talking about that. I belong to a group, and we’ve been researching plosmalogen therapy, and one of the supplements that was created was created with a large amount of phospholine. And,And by itself, when we used the phospholine in one of our formulations, it wasn’t bad, but when they doubled the dose and they were putting it in all of their formulations, people were starting to see the TMO levels go up. And we were trying to figure out, like, what’s happening here. It wasn’t everybody, but it was a good chunk of people, enough for us to say, hey, something needs to change here. We need to take out this phospholine, or not use as much of it. But now this explains exactly why the TAMO was going up. And if those people do have a lot of deuterium, maybe why we saw some people have a problem with it, but not everybody had a problem with it. Seneff 22:57It depends on their microbes. If their microbes are healthy enough to be able to metabolize the TMA, they’re fine. And the microbes produce the TMA, and then they metabolize it. And they’re doing that to generate more deuterium-depleted nutrients. They’re constantly trying to come up with new nutrients that are deuterium-depleted to feed to the host. I mean, they’re really obsessed with it. And they do a good job, normally, but they get so messed up by all these chemicals, and not just glyphosate, of course, all the chemicals in our food and in the air, it’s a mess, you know? Dr. Deb Muth 23:26It’s amazing the body works as well as it does. Seneff 23:28It is. I really am surprised that we don’t have more people who are super sick, you know? Dr. Deb Muth 23:33Exactly. Seneff 23:33Not for sure, but some of us are doing okay with it, you know? Dr. Deb Muth 23:37Yeah, exactly. So when we have this high level of deuterium, high levels of glyphosphate, what is that going to do to the body’s energy stores? Seneff 23:46well, it’s going to wreck the mitochondria, and then you’re going to get chronic fatigue. I mean, I think chronic fatigue syndrome, to me, is a very clear example of mitochondrial damage due to excess deuterium. I think that can completely explain that disease. Dr. Deb Muth 24:01Do you think this high level of deuterium is causing people to see more neurological diseases as well, like Alzheimer’s and Parkinson’s? It’s fueling it. Seneff 24:11Absolutely, because the brain has so much dependence on energy, you know, the brain uses a lot of energy, and they need really healthy mitochondria. They have… neurons have lots of mitochondria. Neurons and muscle cells really, you know, are loaded up with mitochondria, and both of them get injured when they don’t have a… when they can’t keep deuterium out of the mitochondria. Dr. Deb Muth 24:30The cells. Seneff 24:31get injured by all the reactive oxygen the mitochondria are producing, which the ATPase pumps, once they’re getting contaminated with all that deuterium, they start spewing out reactive oxygen. It kills the mitochondria, then it kills the cell, then it kills the brain, you know? It’s like a progression. It really starts with the mitochondrial damage, and then the cell dies, and once the neurons start dying, then the brain dies, you know, and you’ve got all. symptoms. Dr. Deb Muth 24:55So can we measure deuterium like we can glyphosphate in the body? Seneff 24:59You can, yes. In fact, you can do a saliva test and send it off and get the… get a level of how much deuterium is in your saliva. I would love to know more… in more detail how much deuterium is in different parts of the body, because that’s really interesting to me from my studies. What I’m suspecting is that the body… so the cells actually dump deuterium outside the cell. That to try to get as little deuterium as possible inside the cell. And within the cell, they’re trying to get as little deuterium as possible inside the mitochondria. So there’s layers of trying to get rid of the deuterium. And so the convenient thing is to dump the deuterium outside the cell. So there’s a lot of deuterium in bones, for example, probably in your skin, you know, any kind of exterior materials. And the sort of glycocalyx, so there’s this glycocalyx that lines all the blood vessels.That’s these sort of complicated sulfated sugar… complex sugar molecules that, that create gelled water. this gets into Gerald Pollack’s work. I don’t know if you know anything about Gerald Pollack and gelled water, but that’s quite a fascinating field all by itself. But it has to do with really fascinating stuff, because Gerald Pollack talks about battery… a battery being created by the gel. He’s done a lot of research on gelled water. You know, like jello, for example.And you put some powder, you put some hot boiling water, you let it sit, it gels up. It’s mostly water, but it’s a funny phase of water. It’s called the… he calls it the fourth phase of water. He wrote a whole book about that. Gerald Pollack did. And, it’s a gel phase, so water has, you know, the liquid, the solid, the gas, and then the gel. And… and most of the water in our body is gel, is gelled. And especially all the water lining the blood vessels. The blood vessels have free-flowing blood in the middle, right? Dr. Deb Muth 26:46in the long… Seneff 26:46the edges, they have this gelled water that’s created by these sulfated glycos… I mean, the glycans, they’re called, complicated word there, but… They create the gelled water, and the gel… actually, what Pollock showed is that the gel becomes negatively charged, and it pushes out protons. It pushes protons out into the blood. And it ends up being negatively charged because of that. And it creates a battery, and that battery is a source of energy, so… so you can think of, the gel as being like a battery supporting the entire body. All the gel in the blood is a battery. It’s a giant battery. And when you get exposed to sunlight, the gel grows in volume by a lot, and so when the gel gets bigger, it gets to be a bigger battery, and it’s capturing the energy in sunlight. It’s like a solar panel. your skin is like a solar panel, capturing the energy in the sunlight and converting it into this energy in that gel that pushes out those protons. And the cool thing is the deuterons tend to stay behind Because, It’s a little bit of interesting physics here when you have a water molecule, could have one deuterium, one hydrogen, and an oxygen. Water is H2O, right? It would be HDO, one hydrogen, one deuterium, and oxygen, right? HGO. And when you separate that out, usually you separate water out into OH- and H+, right, when you pull it apart into ions. OH minus and H+. Well, what happens here is that the deuterium sticks harder to the oxygen. than the hydrogen does. So you get OD- and H+. more often than OH minus and D+. Dr. Deb Muth 28:22So you have a lot fewer D pluses inside that gel. Seneff 28:26And the H pluses go out into the blood, and the D pluses are… the Ds are stuck to the oxygen, so they don’t go out. So you end up, actually, that’s a sort of distillation process that pulls healthy proteins out of the gel, into the blood. And that makes the blood levels of deuterium lower. Do you see what I’m saying? The deuterium gets trapped in the gel. And the deuterium gets trapped in bone in the same way, in the bone, in the skin. So the body’s trying to keep the deuterium out of the cell, and within the cell, it’s trying to keep it out of the mitochondria, and actually out of all the organelles, not just the mitochondria. So it’s… there’s a whole… Metabolism cannot be explained without looking at deuterium. Dr. Deb Muth 29:07Yeah, so if deuterium’s getting trapped in the bone, much like lead does, does it take up space where we can’t have calcium, and then it leads to more osteoporosis as well? Seneff 29:16I don’t think so. I think deuterium is actually healthy in the bones. Dr. Deb Muth 29:19Interesting. It actually makes the bone stronger, and in fact, there was a really beautiful article on seals. Seneff 29:24You know, SEALs, they do the deep dives, they get into this really, high-pressure zone. Dr. Deb Muth 29:28with… Seneff 29:29in deep water. So they have to be really strong, and the seals actually dope up their bones with twice as much deuterium as what is normal. So they concentrate deuterium. They showed it with the seals, they concentrate deuterium in their bones, and the deuterium makes the bones stronger, so they can sustain the high pressure of the dot. Do you hear the thunder? We’ve got a big thunderstorm. Dr. Deb Muth 29:52So, when you’re testing for deuterium in saliva, are you testing the excess, then? Like, what the body doesn’t. Seneff 30:00Well, there’s the. Dr. Deb Muth 30:00The waste of it? Seneff 30:01It’s really complicated, because I think it’s hard to know how to interpret it. It’s just like when you test for, like, you know, toxic metals, like mercury, like in the hair, you can do a. Dr. Deb Muth 30:13It’s in the hair. Seneff 30:14And sometimes you can find someone who actually has a problem with that metal, but the hair doesn’t show it. Dr. Deb Muth 30:20Bismar. Seneff 30:21doesn’t actually excrete it in the hair, so you have to think about Can the body get rid of it that way? And actually, in the saliva, I believe the saliva the body concentrates deuterium in the saliva, because it’s trying to get rid of deuterium. So a way to… you have the salivary glands, and they can actually excrete, preferentially excrete deuterium. Into the saliva. to concentrate it there in order to keep it out of the body. But those enzymes that do that might be compromised, in which case you have less deuterium in your mouth, but that doesn’t necessarily mean that’s good. You see what I mean? So when you see whatever the level is, it’s hard to interpret it, I believe. Dr. Deb Muth 30:58Yeah, it’s hard to tell what to do with it, then. Seneff 31:01Yeah, whether it’s low because your salivary glands aren’t working well, or whether it’s low because your whole body’s low, you know? And you can’t really know which way that goes, necessarily. So that makes it hard to interpret, I think. Dr. Deb Muth 31:13It sure does. Seneff 31:15I’m interested, for example, breast milk has low deuterium. Saliva has high deuterium. And you’re… I haven’t been able to find… there’s very few measurements, so I’d like to see a lot more measurements on the… just what’s typical, you know? Right. Dr. Deb Muth 31:31expect the urine to have hydrocherium, so anything that you’re excreting, I would expect it to have hydrocherium. So, knowing this information that we have, how does one fix these metabolic issues that we’ve kind of created in our own environment, for lack of a better term, because of our own… our own misgivings of what we’ve done in the world. How do we protect our brain and repair that metabolic issue in the mitochondria these days, then? Seneff 31:58I would say the most essential thing is to eat certified organic food. Dr. Deb Muth 32:02Always buy certified organic. It doesn’t guarantee that it’s free from chemicals, but it’s generally better. Seneff 32:07So that’s… we’ve been practicing that ever since 2012, when I figured out that glyphosate is causing a mess. So we went organic, and we’ve been like that ever since. We did a purge, we threw away everything, even the spices, started over in our kitchen. Yeah. In 2012, and then we’ve just been consistently buying certified organic ever since then. Dr. Deb Muth 32:27at least lowers the load, right? I mean… Seneff 32:29Yeah, it’s. Dr. Deb Muth 32:30There could be… Seneff 32:30some contamination. Dr. Deb Muth 32:31there, but… Seneff 32:32It’s a lot less, generally, but not zero, not necessarily zero. Dr. Deb Muth 32:35Right. Seneff 32:36undetectable. But that’s a really important thing. Another thing is to eat… I think eating fiber can help the microbes to produce those low-deuterium nutrients. The microbesWe can’t digest… our cells don’t know what to do with fiber, but the microbes can digest the fiber, turn it into hydrogen gas, turn it back into nutrients, like short-chain fatty acids, you know, butyrate. So, by eating foods that contain fiber, you’re helping the microbes to produce butyrate, and butyrate is really, really important for the health of the colon, you know? Dr. Deb Muth 33:07Yeah, and we’re talking about eating whole food organic, not organic Doritos and Cheetos. Seneff 33:13Right, right. Dr. Deb Muth 33:14kinds of things, right? Seneff 33:15Whole foods is really important. I always say whole foods and organic foods, those are the two really important things. And then I don’t really, you know, there’s all these different fad diets with respect to, a loss of fat, or no fat, and all that kind of thing. I don’t buy into any of those. I think you just want to have a balanced diet.Carbs are okay, you know, fats are really healthy, and especially animal-based fats are healthy. I don’t like a vegan diet, because I think animal-based foods provide certain nutrients that are really hard to get otherwise. And like I say, you can’t take choline by tartrate to replace the choline that’s in the animal-based foods. Dr. Deb Muth 33:48Right. Yeah, I’ve worked a lot, and I’ve never seen a healthy vegan. I mean, we can say we’re vegan.But those people are eating a lot of junk food, typically. They’re not true vegans, where they’re just eating whole food and getting all their nutrients from good quality foods. Most of the people that I’ve worked with over the years that have been vegan eat a lot of processed foods, a lot of junk foods. It just doesn’t include the animal fats, and then that makes them unhealthy, and we see a lot of nutrient deficiencies and a lot of pain and energy issues. It’s very hard to be a healthy vegan. In my opinion, as well. Seneff 34:20I agree, I agree, yeah. Dr. Deb Muth 34:23So I like to ask this question of all of my guests, and if you were designing a public health policy tomorrow, what would your first change be? Seneff 34:32To switch the farming system to be small farms that are regenerative, not just organic, organic regenerative small farms, with no use of chemicals. Dr. Deb Muth 34:42Yeah. Seneff 34:43No insecticides, no fungicides, no herbicides, nothing, you know? And even natural fertilizer, of course, as well. Of course, right now, you know, the organic farms rely on the chickens to get. Dr. Deb Muth 34:57the. Seneff 34:58Manure, which has glyphosate in it, so they… they get their glyphosate from the manure. Dr. Deb Muth 35:04Yeah, because a lot of that chicken feed has glyphosate in it, and then they’re passing that through, and we think that it doesn’t pass through, but it does pass through, and… Yeah, I would agree with you. I think when we went to these big industrial farming practices, we did not do ourselves any favor. And shipping food across the country to be slaughtered, only to ship it back here. Seneff 35:29It doesn’t make any sense, and… Dr. Deb Muth 35:32Growing things in environments where people live that isn’t natural to them, that doesn’t make sense to me either, in a lot of ways. Seneff 35:41Yeah, it’s very frustrating, because I think we really… it’s too bad that we lost all those small family farms, because we need them back. We really need them back, and I think that’s really the… and you want to have a variety of different crops, you know, we have all these massive cornfields, that’s just wrong. Dr. Deb Muth 35:55Yeah. Yeah, and they do nothing but corn until…Until your county says you have to do something different now, because you’ve depleted the soil too much, and they don’t want to put any soil preservation back in, and put any nutrients back in, because that’s expensive. Seneff 36:12Exactly. Dr. Deb Muth 36:13And then they’ll rotate the crop maybe once a year, and then they’re back to growing corn again, because that’s the largest revenue producer for them at the time, and it really is a challenge for us. Really a challenge. Seneff 36:26Yeah, it’s going to be very difficult to pivot to the kind of agriculture we need, and if we don’t do it, we’re just going to get sicker and sicker. Dr. Deb Muth 36:33Like, my friend. Seneff 36:34frightening. Dr. Deb Muth 36:35Yeah. Seneff 36:35How sick we are. Dr. Deb Muth 36:37Yeah, and I think people trying to grow their own food, at least some of it, can be really helpful and beneficial, too. We need to go back to that practice. Seneff 36:44I know, yes, rooftop farms, right? Dr. Deb Muth 36:47Back in the city. Seneff 36:48That’s really quite cool. I’ve heard some lectures on that. Dr. Deb Muth 36:51Yeah. Yeah, even some of the hydroponic growing that you can do in your apartment and get some lettuce and some herbs and things like that. I mean, anything that you can grow yourself, I think, is a big benefit. A, you don’t. Seneff 37:03I think it’s. Dr. Deb Muth 37:04B, you know how it’s been grown. C, it’s just healthier for you, and it’s less that you’re gonna have to buy that you don’t know that, what’s been growing in it, so… Seneff 37:13And it’s also kind of fun, right? You feel good that you’ve produced your own food. I think it’s really quite neat. Dr. Deb Muth 37:18Yeah, and there’s something, therapeutic about digging in the dirt a little bit, and getting your hands dirty. Seneff 37:24It’s really good to be outdoors and getting exercise. I mean, really, the work that’s involved with growing food is quite healthy work, really. Dr. Deb Muth 37:31Yeah, it’s a lot of work, for sure. That it is. So, for listeners that might be feeling a little overwhelmed about what we’re talking about, and thinking about, how do I detox or nutrition, where do I get some of this education, what kind of resources would you recommend for them? Seneff 37:47That’s a tough one. There’s not much known about deuterium, so it’s really quite difficult to… you can search deuterium, and there are some… a couple of good resources, which I can’t name, I could probably send you a link, describing deuterium. I know there’s a woman who’s written some nice material. on deuterium, just to get a sense of… more… a better sense of what it is, and why it’s a problem. But there’s not much. I mean, we need to have a lot more. I really want to get the research community aware that. Dr. Deb Muth 38:17They need to be. Seneff 38:17researching deuterium and its role in the body, because I think it’s absolutely essential. We’ll never understand disease if we don’t look at deuterium. Dr. Deb Muth 38:24Yeah, I think so, too. I think… I think the… there’s a lot of amazing discoveries that are being found. That could open the doors and give us answers to reversing a lot of disease, if there was funding behind it, if there were people like you that were interested in it, to really dig down from a functional medicine standpoint and try to figure it out instead of looking at it from a big pharma aspect, where we just need to find a pill that’ll fix it. Seneff 38:50I know. Dr. Deb Muth 38:51There are not pills that are going to fix these kinds of things. Seneff 38:54Right, yes, pharma’s way off base, I think. They’re really going after the completely wrong approach to health. Dr. Deb Muth 39:01I agree. Well, thank you so much for joining me today. It’s been a pleasure. Is there any last words that you want to leave with our listeners? Seneff 39:09I don’t know, I just, you know, healthy living is basically just eating whole foods, eating organic foods, getting plenty of fiber and fermented foods.And healthy fats, you know, sort of a variety of diet, a really mixed diet. Lots of fresh vegetables. I mean, there’s all these different great things to eat. Just stay away from the soy protein bars, you know, and the candy bars, and that sort of thing. And the cookies, I mean, just, you know. And then, of course, getting outside in the sunlight is something I always have to say. I love the sun. I think it’s very therapeutic, and we don’t get enough sunlight. We’re just. Dr. Deb Muth 39:43We don’t. And if we do, then we’re lathering on all of our sunscreen so that we don’t get the sun, and that’s creating its own issues, right? Seneff 39:51That’s right. Dr. Deb Muth 39:54Well, thank you so much for being with me today. Seneff 39:56Thank you. My pleasure. Dr. Deb Muth 40:03Thank you for joining me today on Let’s Talk Wellness Now. If this episode has resonated with you, share it with another woman ready to reclaim their health and their vitality. And remember, wellness isn’t just about feeling good, it’s about thriving in every area of your life. If you’re ready to explore personalized regenerative medicine. Please visit serenityhealthcarecenter.com. You can also follow me on social media, and join our free programSeen at Last community on Facebook. Until next time, I’m Dr. Deb, reminding you to care for your body, mind, and spirit. Be well, and I’ll see you on the next episode. Meta Boxes Use up and down arrow keys to resize the meta box pane.Toggle panel: AIOSEO Settings SERP Preview Let’s Talk Wellness Now https://letstalkwellnessnow.com › 2026 › 06 › 05 › episode-267-env…The post Episode 267 – Environmental Toxins, Nutrition, and Their Role in Chronic Disease Development first appeared on Let's Talk Wellness Now.

Well it finally happened! One of our 50 states has decided to ban the herbicide that got no-till started in the early years before glyphosate came along. It happened in Vermont, a state with an extremely low acceptance of no-till that has decided to ban the use of paraquat amid growing concerns about links between paraquat exposure and Parkinson's disease.

Check out this great show from April 21, 2026 Father Peter Armenio joins Patrick to discuss Finding Joy in a Life with Christ (8:06) Joy the midst of suffering. (18:29) Break 1 Janet - Person who I find joy from...Right after Vatican 2, she helped prepare laity what sisters couldn't help with. Did it so peacefully. Loved to talk about the Lord and catechesis. (24:32) Angelo - Dealing with mother who has dementia. Trying to find joy in this. Looking for some inspiration. It's been difficult. (33:05) Matt - My dad's side is from Denmark. Grandffather had a tough life. settled in small town. A lot of these people have had difficult lives. When you struggle and suffer with Christ, you find great joy and community and unity. It's a beautiful thing. (37:42) Break 2 Ann - When I was doing work with husband in the missions, we met a lady who made a pie, so kind and sweet. One day, I went to her house and I noticed how messy her house was. I found out later she suffered from back problems. She was always doing such good things for others. I felt bad for being judgmental. She radiated Christ. (42:27) Joy lived out in a deep way. Prayer brings joy. (47:07) Email from Lisa about her mom with Parkinson’s Encounters with true Joy in evangelizing.

Decode Autoimmune with Phil George Are you curious about autoimmune diseases and how to stay ahead of them? Join biochemist Phil George in this eye-opening episode as he breaks down:  What autoimmune disease really is  The root causes behind it  How to prevent it before symptoms strike  The essential tests you need to catch it early Whether you're health-conscious or just want to understand your body better, this episode is packed with actionable insights that could change your life. Prevention starts with knowledge—tune in and take control of your health. Available now on all podcast platforms. This Week's Video- Emerging Science on Light Therapy Treatments for Alzheimer's, Parkinson's, and Concussion Recovery--with Dr. Emily Cabrera--a must listen! https://youtu.be/IezwTJX1gBk?si=EKujM0EXmXJS_2yW   Please feel free to email Phil at philgeorge@charter.net with any health/nutrition/exercise questions. https://www.wellnesswave.net/

How Going Broke Made Me Rich A while back, I lost everything. Not "everything" the way people say it after a rough quarter. I mean I opened my banking app one day and saw a number with no digits in front of the decimal. Zero. The kind of zero that makes you sit very still for a minute. I'd been earning a million dollars a year. And then I wasn't earning anything at all. Here's the strange part, and it's the reason for this post and the episode it goes with: losing it might be the best thing that ever happened to me. If you've ever been afraid of losing what you've built — or you're in the middle of losing it right now — stay with me. "The recent unpleasantness" I've started calling it that, with a little wink, "the recent unpleasantness" (what's that movie? Anyone know?). It began with Parkinson's. Then the pandemic, which was not a gentle season for anyone running a business. Then shoulder surgery. Then brain surgery — and I want you to notice I just dropped "brain surgery" in next to "shoulder surgery" like I was listing errands. Add a few business decisions I'd love to have back, some personal ones I'd file in the same drawer, medical bills that arrived looking like phone numbers, and overhead that had grown to the size of a small kingdom. Underneath all of it, quietly, a crisis of faith. Not a wobble. A genuine dark night of the soul, the kind St. John of the Cross wrote about, where God seems to have left the room and shut the door, and you stand in the dark wondering if any of it was ever real. At the bottom of it, I declared bankruptcy. I'm not telling you this to perform my suffering. I'm not complaining. We're rebuilding, and I'm a new man — by the grace of our Lord Jesus Christ, and I mean that as plainly as I can say it. So here's the question I had to ask myself. When I say going broke made me rich, is that just a clever line? A copywriter's sleight of hand? Or can a man say a thing like that and be telling the truth? It's true. Here's how. What was actually load-bearing When you get stripped all the way down, you find out what was holding the house up. I'd built a life with a lot of stuff in it. Income. Status. A reputation in my corner of the marketing world. The comfort of knowing the bills were handled and then some. None of that is wrong. I'm not here to tell you money is the problem and poverty is the cure — that's a sermon people preach when they've never actually been broke, and it's nonsense. What happened was simpler. Everything that wasn't essential got taken away, and I was left holding only what was. And the list of things that are truly essential turns out to be far shorter than the list of things I'd convinced myself I couldn't live without. Corrie Ten Boom said it better than I can: you don't learn that Jesus is all you need until the day He's all you have. I used to read that as a needlepoint-pillow kind of line. Then I lived it, and it stopped being a pillow and became the floor I was standing on. Because when you've got nothing left but God, you find out fast whether God is enough. He is. Not because I read it somewhere — because I tested it against the wall, with nothing to fall back on, and it held. What grew in the low place I spent a lot of that season on my knees. I mean that literally, not as a figure of speech. Some mornings I was flat on my face on the floor, talking to God. Sometimes not even talking. Just there. Out of words, out of plans, out of the energy it takes to keep pretending you've got it handled. And in that low place, things grew that had never had room before. Real humility — the kind that comes from running out of options and realizing you were never as in control as you thought. A habit of seeking God's will before a decision instead of after, when I just needed Him to bless what I'd already chosen. A patience I did not previously possess; ask anyone who knew me in the old days. I became a better husband, a better parent, a better friend, a better follower of Jesus. Not better than you, or anybody — better than the man I used to be. That's the only fair comparison there is. And the new one is a better creature. A reborn one. That's not a marketing claim. It's a report from the field. A different kind of builder I'm rebuilding the business now, with a few good people helping me, and it's going well. But it's going well in a completely different way. Before, I built fast and big. I added overhead like it was a hobby. If something looked like it might work, I threw money and people at it and sorted the details later. This time it's slow, methodical, almost annoyingly careful. Not because I've gotten timid — because I've become a different kind of business person. The fast-and-big version of me was running on a need to prove something, to be impressive, to outrun a fear I couldn't have named at the time. That guy got retired during the unpleasantness, and the fellow who replaced him builds differently. Going back through my old courses and trainings as part of the rebuild, I found most of it was sound. Well-built. Stuff I can stand behind. I'll say that carefully, because there's a version of it that's just bragging in modest clothing. I'm not proud of the work. I'm pleased by it — and there's a difference. Proud takes credit and puffs up. Pleased just looks at the thing honestly and notices the foundation's still square. The shortcut Here's where I land the plane. Some of us are slow students. I'll put myself first in that line. Apparently I'm the kind of student who needs the painful version of the lesson — going broke financially, physically, spiritually, getting taken all the way down to the studs before I'll finally surrender to God's will. That's how I learned it. The hard way. The expensive way. It doesn't have to be that way for you. You could skip all of it and go straight to the mercy seat. Straight to surrender and humility and trust, and find the freedom there before the tragedy ever shows up. The lesson is available without the tuition I paid. I had to lose everything to learn God was enough. You could simply decide He's enough today — on a perfectly ordinary Tuesday, business intact, bank balance healthy, nothing dramatic happening at all. Surrender now, while it's a choice, instead of later, when it's the only option left. That's the shortcut, and it's a real one. So if everything's going fine and you've been holding God at arm's length because you don't feel like you need Him at the moment — go to your knees anyway. Not out of crisis. Out of wisdom. Get there the easy way. And if you're in the dark right now, door shut, God seemingly gone from the room, hear this from somebody who's been exactly where you are: He hasn't left. It feels like it. I know. But the floor is still there in the dark. I found it. It held me. It'll hold you. Going broke made me rich. I mean that every way it can be meant. I lost the money and found the things money was always a substitute for, and knowing what I know now, I wouldn't trade back. This is the written companion to this week's episode of The Ray Edwards Show. If it landed, go listen to the full conversation — and then go do the thing only you can do. And remember whose you are.

The Care Advocates is brought to you by the All Home Care Matters Media team and focuses on providing family caregivers and their loved ones with support, resources, and discussion on the issues facing them in the matrix of long-term care.   The Care Advocates are co-hosted by Lance A. Slatton & Dr. George Ackerman.   The Care Advocates are honored to welcome Anne Smith as guest to the show.   About Anne Smith: Anne Smith shines a light on the often-overlooked realities of Parkinson's disease and the profound impact it has on both those living with the condition and the family members who care for them. In this powerful conversation with Lance A. Slatton, Anne discusses the growing number of Parkinson's diagnoses, the emotional toll of watching a loved one's health decline, and the financial challenges many families face after stepping away from careers to become full-time caregivers. Her insights offer a candid look at the sacrifices, struggles, and resilience required when navigating life with Parkinson's disease.   Anne also addresses one of the most important and sensitive topics in caregiving: caregiver burnout. Drawing from her own experiences and observations within caregiver communities, she speaks openly about exhaustion, sleep deprivation, frustration, and the emotional strain that can accompany caring for a loved one with Parkinson's. This meaningful discussion serves as both an educational resource and a reminder that caregivers need support, understanding, and compassion just as much as those they care for.

Swallowing changes are one of the most overlooked—and most important—symptoms in Parkinson's disease. In this episode (see on YouTube), we break down how swallowing works, how Parkinson's can interfere with it, and the signs that may point to dysphagia (swallowing difficulty). We cover:  • The normal phases of swallowing • How Parkinson's affects swallowing function • Common signs of dysphagia • Why liquids are often the hardest thing to swallow • What people should *not* try on their own • Why a proper swallowing evaluation matters We also explain the difference between a **Modified Barium Swallow Study (MBSS)** and **FEES** (Fiberoptic Endoscopic Evaluation of Swallowing), when each is used, and why it's important not to make changes—especially thickening liquids—without professional guidance. If swallowing has become more difficult, more frustrating, or more concerning, this episode will help you understand what's happening and what to do next. —

To have Dr. Morse answer a question, visit: https://drmorses.tv/ask/ All of Dr. Morse's and his son's websites under one roof: https://handcrafted.health/ Facebook Page: https://www.facebook.com/handcrafted.health 00:00:00 - Intro - Diet - Spirituality 00:07:07 - Ehlers-Danlos Syndromes (EDS) - Acid Reflux - Sleep Apnea - Premature Ventricular Contractions (PVCs) - Premature Atrial Contractions (PACs) - POTS - Lax (Painful Joints) - Thoracic Outlet  syndrome (TOS) - Mast Cell Activation Syndrome (MCAS) 00:27:49 - Chronic Strep Throat 00:42:25 - AERD - Asthma - Chronic Sinusitis with Nasal Polyps - Bronchitis  - Bronchiectasis 01:08:42 - Depersonalization/Derealization - Social Anxiety - Shyness - Low Self-Esteem  01:31:27 - Parkinson's Disease - Breast Cancer - Hashimoto's Disease 00:07:07 - Ehlers-Danlos Syndromes (EDS) - Acid Reflux - Sleep Apnea - Premature Ventricular Contractions (PVCs) - Premature Atrial Contractions (PACs) - POTS - Lax (Painful Joints) - Thoracic Outlet  syndrome (TOS) - Mast Cell Activation Syndrome (MCAS) The breathing and heart issues are scary. 00:27:49 - Chronic Strep Throat After all the antibiotics, I had a really bad flare-up and struggle with fatigue. 00:42:25 - AERD - Asthma - Chronic Sinusitis with Nasal Polyps - Bronchitis  - Bronchiectasis I am currently taking steroid medications. 01:08:42 - Depersonalization/Derealization - Social Anxiety - Shyness - Low Self-Esteem  I have also experienced depression, paranoia, fear, intrusive thoughts, chronic fatigue, and irritability—the whole nine yards. 01:31:27 - Parkinson's Disease - Breast Cancer - Hashimoto's Disease I want to start your program. I didn't do chemo or radiation.

The June 2026 Recall highlights four previously posted episodes on parkinsonian disorders. The episode begins with Dr. Valtteri Kaasinen discussing the clinical challenges of diagnosing Parkinson disease and how that diagnosis can evolve over time. The discussion continues with Dr. YuHong Fu, who addresses the importance of differentiating between dementia with Lewy bodies and Parkinson disease dementia. The third episode features Dr. Daniel Weintraub discussing clinical considerations and strategies for effective communication when addressing cognitive concerns in patients with Parkinson disease. The episode concludes with Prof. Franziska Hopfner discussing the frequency and disease trajectory of MSA patients who do not experience dysautonomia, compared with those who have autonomic involvement. Podcast links:  Stability and Accuracy of a Diagnosis of Parkinson Disease Over 10 Years  Dementia with Lewy Bodies and Parkinson Disease Dementia Clinical Approach to Dementia Risk in Patients with Parkinson Disease  Multiple System Atrophy Without Dysautonomia  Article links:  Stability and Accuracy of a Diagnosis of Parkinson Disease Over 10 Years  Dementia with Lewy bodies and Parkinson Disease Dementia — The Same or Different and is it Important?  Long-Term Dementia Risk in Parkinson Disease  Multiple System Atrophy Without Dysautonomia: An Autopsy-Confirmed Study Disclosures can be found at Neurology.org. 

Hour 3 for 6/1/26 Drew welcomes Dr. William Supple, PhD to discuss his book Cancer is a Parasite (1:00). Topics: if taking Fenbendazole can be preventative (21:35), Parkinson's (31:40), myeloma (36:27), Ivermectin (37:10), Fenbendazole (41:19), and HPV (45:14). Link: Cancer is a Parasite Book

IUL gets pitched to young professionals, families, business owners, retirees, and pretty much everyone in between. The message is always consistent: this product can solve your financial problems, provide market upside with downside protection, and generate tax-free retirement income. One product, all things to all people. For most people, IUL is the wrong tool entirely. Not because it's fraudulent. Not because it can't work for anyone. But because there's a fundamental mismatch between how it's sold and who it actually serves. And that mismatch shows up in the data.  https://youtu.be/fZS1uPmsCS0 According to a 2021 study by Gottlieb and Smetters, published in the American Economic Review (1) and drawing on SOA and LIMRA persistency data, nearly 88% of universal life policies never pay a death benefit. That figure covers all universal life products, including IUL.  And IUL was built specifically to fix the lapse problems of earlier UL products. It hasn't. The chassis is the problem. This article is a profile-by-profile look at the people who should not buy an IUL, the data that supports why, and a fair look at the narrow group for whom it might make sense. We're not taking sides. We're giving you the information you need to make a decision that actually fits your life. Key Takeaways:What IUL Actually Is, and Why the Chassis MattersThe One-Year Renewable Term ProblemWho Should Not Buy an IUL PolicyAnyone who hasn't mastered the financial basicsAnyone who needs guarantees and predictabilityAnyone practicing or planning Infinite BankingAnyone without a high, stable, long-term incomeAnyone who cannot handle the lapse riskAnyone who misunderstands what market risk means in an IULAnyone building a multi-generational legacyThe Data Nobody Shows You Before You SignThe Headline NumbersA Pattern That Keeps RepeatingTo Be Fair: Who IUL Actually ServesThe Right Buyer ProfileThe Alternative Built for the Rest of UsWhy Endowment MattersThe Reduced Paid-Up Safety NetBehavioral FitThe Decision Is Yours: Make It With the Full PictureBook a Strategy CallFrequently Asked QuestionsWho should not buy an IUL policy?Is IUL worth it for most people?What is the lapse rate for IUL policies?Who is IUL actually designed for?What is the difference between IUL and whole life for banking purposes?Can I use IUL for Infinite Banking? Key Takeaways: IUL is built on a one-year renewable term chassis, meaning internal insurance costs rise every single year as the policyholder ages Nearly 88% of universal life policies (including IUL) never pay a death benefit, with 57% of permanent policies (particularly universal life) lapsing in the first 10 years IUL cannot endow and cannot be converted to reduced paid-up status, meaning premiums are required indefinitely The product demands a level of behavioral consistency over 30 to 40 years that most people, including the most disciplined, cannot sustain IUL is not compatible with Infinite Banking because it lacks the guaranteed, predictable cash value growth the strategy requires The narrow group IUL actually serves is sophisticated, high-net-worth individuals using it specifically for estate planning leverage What IUL Actually Is, and Why the Chassis Matters Indexed universal life insurance is a form of permanent life insurance where cash value growth is linked to a market index, typically the S&P 500.  The policyholder isn't actually invested in the market. The insurance company credits growth based on index performance, subject to a cap (the maximum you can earn) and a floor (usually 0%). You participate in some of the upside. You're protected from direct index losses. That's the pitch. The One-Year Renewable Term Problem The structural reality is different from the marketing version. Unlike whole life insurance, which spreads insurance costs evenly across a lifetime so the premium never changes, IUL is built on a one-year renewable term chassis. That means the cost of insurance increases every single year as the insured ages. In the early years, you barely notice. Over decades, and especially in retirement, it becomes a serious structural pressure on the policy's cash value. The flexible premium feature, often marketed as a benefit, is part of the same structural reality. Flexibility sounds good. But it means the policy requires ongoing management and can deteriorate if premiums are reduced or skipped.  The policy doesn't just sit there working for you. It demands attention, funding, and active monitoring year after year. For a deeper look at the structural risks, internal charges, and illustration problems with IUL, see our posts on the dangerous truths about IUL risks and Todd Langford's analysis of IUL math. Who Should Not Buy an IUL Policy This is the core question. Not "is IUL good or bad?" but "is the person buying it actually a match for what the product demands?" Seven profiles. If you recognize yourself in any of them, that's information worth taking seriously. Anyone who hasn't mastered the financial basics IUL is an advanced financial product. It should not be anyone's first or second financial move. Before using a structure that combines insurance, investing, and tax planning, a person needs the basics in place: spending less than they earn, building consistent positive cash flow, and saving habitually. Parkinson's Law, the tendency for expenses to rise to meet income at every level, is real. IUL does not fix a cash flow problem. It adds complexity on top of one. If you haven't overcome the basic discipline of keeping your income above your expenses and putting the gap into savings, a complex product isn't a solution. It's a distraction from the actual problem. Anyone who needs guarantees and predictability If you need to know with certainty what your policy will be worth in 10, 20, or 30 years, IUL cannot give you that. There is no guaranteed cash value dollar amount in an IUL. The crediting depends on index performance, caps that can change annually, and internal costs that increase over time. If your financial planning requires a predictable future asset base for retirement, a major capital need, or a legacy strategy, a product built on variables is the wrong foundation. The middle class, upper middle class, and anyone with fluctuating income fall into this category. And that's most people. Anyone practicing or planning Infinite Banking IUL is actively marketed as a vehicle for Infinite Banking. It is not.  Infinite Banking requires a pool of capital that is predictable, guaranteed, and always growing. The arbitrage that makes policy loans powerful, earning in two places at once, only works when the policy's growth is reliable. In a year where the index earns zero, a policy loan doesn't just cost the loan interest. It costs the loan interest with no offsetting policy growth.  The banking system breaks down exactly when it should be working hardest. For a full breakdown, see our post on why IUL is incompatible with Infinite Banking. Anyone without a high, stable, long-term income IUL requires consistent, maximum funding over a very long time horizon to have any chance of performing as illustrated. Life disruptions like job changes, business downturns, family expenses, and medical costs interrupt premium payments. And because the policy relies on the index to help fund its own rising costs, any gap in funding creates a cascade effect that's very difficult to reverse. Even Nelson Nash, the creator of Infinite Banking, once missed funding PUAs on one of his own policies, causing the rider to close. If the creator of the strategy had trouble keeping up with premiums, the expectation that ordinary policyholders will fund an IUL perfectly for 30 to 40 years is unrealistic. Anyone who cannot handle the lapse risk Nearly 88% of universal life policies never pay a death benefit, and IUL is part of that picture. That number should stop anyone from considering this product and make them ask: why?  The answer is structural. Rising internal costs, non-guaranteed crediting, and the behavioral reality of managing a complex financial product over decades. And lapsing isn't just losing the policy. When a policy lapses with outstanding loans and cash value above the cost basis (the total premiums paid), the gain is treated as taxable ordinary income in the year of lapse. That tax bill arrives at the worst possible time, often in retirement, when income is fixed and absorbing it is most painful. Anyone who misunderstands what market risk means in an IUL Many buyers hear "zero is your floor" and believe their money is protected from losses. This is technically true and practically misleading. The 0% floor only protects against index-linked losses. It does not protect against the internal drag of rising mortality costs, administrative fees, and hedging strategy expenses, all of which continue to come out of the cash value regardless of what the index does. A zero-credit year is effectively a negative year once internal charges are factored in. And when markets perform poorly over multiple years, the insurance company's cost of maintaining those hedges rises. They respond by lowering caps. Lower caps mean less upside potential. This cycle of poor performance, higher hedge costs, and lower caps compounds over time. Anyone building a multi-generational legacy Legacy planning requires certainty across decades and generations. A policy that cannot endow, cannot be converted to reduced paid-up status, and requires active management indefinitely is not a reliable foundation for generational wealth transfer. Whole life policies endow at age 120 or 121. The cash value and death benefit converge, and the policy is contractually complete. IUL policies do not endow. Premiums are required for as long as the insured lives. There is no actuarial endpoint.  ...

In this episode, Brian Luebben breaks down the exact framework he has used to work six months a year while building a business doing over $10 million in revenue.Brian covers:Why both corporate America and traditional entrepreneurship broke himThe two seasons every high performer needs: acceleration and navigationHow reverse goal setting and Parkinson's Law make him more productive in less timeWhat his actual calendar looks like and how he knows when to switch seasonsWhy navigation is not vacation and how to tell the differenceHow to apply this framework whether you have a nine to five, young kids, or a growing businessThis is one of the most honest conversations Brian has had about how he actually structures his life and business - and why the finish line is never coming. Curious as to how we've bought multiple businesses and built millions in equity? Give this episode a watch for a full breakdown: https://www.youtube.com/watch?v=cviipnGtDWI&feature=youtu.beIf you are serious about building a life on your terms and want to surround yourself with people who are actually doing it, go to: https://actionacademy.com?el=action_academy_podcastIf you want to leave corporate America in the next 6-18 months - you should check out our Action Academy Community

What if aging isn't inevitable — it's just your body losing the ability to repair itself? Live from the Beyond Biohacking Conference in Austin, Jason Rantz sits down with Christian Drapeau, the scientist and stem cell pioneer behind Stemregen. For nearly 30 years, Drapeau has championed a radical idea once dismissed by mainstream science: that your own stem cells are your body's natural repair system — and that releasing more of them, without injections or needles, could be the key to fighting aging and chronic disease. In this interview, Drapeau breaks down what stem cells actually do, why they decline as we age, and how endogenous stem cell mobilization differs from costly stem cell injections. He shares jaw-dropping early results from his clinical studies on congestive heart failure and Parkinson's disease, explains why academia and conventional medicine lag behind the science, and details exactly how Stemregen's plant-based approach works in the body within hours. If you care about longevity, regenerative medicine, biohacking, or simply staying healthier longer, this conversation will change how you think about your body's ability to heal itself.

The last few years handed me a stack of things I never ordered — Parkinson's, brain surgery, a pandemic, and financial pressure I've talked about openly in older episodes and on YouTube. In this brand-new, unedited, "live-to-drive" relaunch of The Ray Edwards Show, I'm not going to rehash the wounds. I'm going to do something more useful: I'm going to hand you the scars. Because the scars, as I've come to see it, are the curriculum. And what I learned in that fire has rewired everything I teach about building a business in this strange, contracting, AI-rewired moment — including why nearly every entrepreneur I meet is trying to build a personal brand in exactly the wrong order.. Here's a peek at what you'll discover when you press play: The tight little phrase I now use to describe my current state of freedom — and the brutal price I paid over the last few years to earn the right to say it. The disease: "out-of-sequentialism". You probably have it -- becuase it's quietly killing almost every coach, consultant, and creator online right now (my friend Armand Morin gave it the name) — and the embarrassingly simple test that tells you in 30 seconds whether you've got it. The Tony Robbins example about a dog and a kid named Johnny — and what it reveals about why your message isn't landing, no matter how much copy you rewrite. The dollar-store habit I credit with saving more of my best ideas than any AI tool, app, or "second brain" system ever has — and the three reasons it still humiliates your phone in 2026. (Hint: Alex Mandossian was right.) The single Bible verse I call "the entire permission slip" you need to stop hiding your gift from the marketplace — and how to read it without the religious baggage that's kept you small for years. Why "the ultimate sacrifice" wasn't REALLY the ultimate sacrifice — and the surprisingly mercenary reason Jesus did what he did, according to the Book of Hebrews. (Some pastors will not love this segment. I'm at peace with that.) The Casey Neistat number proves you don't need to be famous, funded, or follow-rich to build a business that buys back your life. (He started $200,000 in debt. With a camcorder.) The difference between Mission and Vision — confused by 95% of the entrepreneurs I've coached — and the single reason their goals never compound into anything bigger than a to-do list. The deceptively simple Destiny Formula that turns vague mission statements into something you can actually wake up and execute on Monday morning. Why "fair" does not mean "equal" — and how getting this one distinction wrong will keep you stuck in quiet resentment for the rest of your business career. The "interruptibility test" I use to decide whether a business is actually worth building — and why most "successful" entrepreneurs fail it without realizing it. A coffee shop in Spokane called Revel 77 — and the one thing it does that quietly destroys generic competitors without ever undercutting them on price. (You can steal this for any business, in any niche, this week.) Why marketing is NOT what you think it is — and the three-word definition that makes it 10x easier to do, even if you've never written a sales letter in your life. The Earl Nightingale "fireplace" line that exposes why most entrepreneurs are quietly broke. (You've made this exact mistake. Probably this week.) The reverse-engineering math that turns a $104,000 income goal into one doable, repeatable weekly task — no hype, no hustle-bro nonsense, no hopium. Why "lead magnets are dead" is one of the dumbest things being said online right now — and the value-first sequence that still prints money in 2026 (and will print more of it in 2027). The three traits every piece of marketing must have to spread on its own. The War of Art has all three. Your Best Year Ever has all three. Yours probably has one — at best. The "modern elder" our culture has discarded — and why being over 50 may be your single biggest unfair advantage in the AI era. (At 60, I'm making the case.) The four questions you must answer about your customer — in this exact order — before you write a single piece of sales copy, run a single ad, or post a single piece of content. The one phase that, when skipped, makes every other phase collapse — and the surprisingly philosophical question you must answer to nail it. (Most entrepreneurs would rather do anything than sit with this question. That's the tell.) What "destiny" actually means, etymologically — and why you can change yours today, even if today turns out to be the only day you have left. Press play. Pull out the pen and notebook I'll tell you to grab anyway. And get ready to find out exactly which phase you've been skipping.

Dale Earnhardt Jr. sits down with longtime fixture in the NASCAR garage, Morgan Shepherd, to learn about his journey from bootlegging to becoming a multi-time Cup Series winner. Born in Ferguson, North Carolina, Shepherd followed his father Jesse Clay's footsteps into the moonshine lifestyle. It was here he honed his driving skills, and after a close call with the police scared him straight, he decided to exercise fast driving on the local short tracks. He took to the legendary Hickory Motor Speedway and began winning on a regular basis in the late model ranks. Through the 1970s, Morgan began moving up the NASCAR Late Model Sportsman rankings before winning the national crown in 1980. This accomplishment catapulted Morgan into full-time Cup competition, and before long, he would pick up his first win in the top level of stock cars, at Martinsville in 1981, driving for Cliff Stewart. Morgan drove for a litany of owners throughout his Cup career and would park cars in victory lane on four different occasions. He spent the latter part of his driving days chauffeuring rides for his own team, breaking several age-related records along the way. Morgan would make his 1000th NASCAR national start in 2018 at the tender age of 76. Morgan joins Dale Jr. for a conversation about his legendary career and his current battle with Parkinson's disease. Check out Dirty Mo Media on YouTube: https://www.youtube.com/@DirtyMoMedia Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.