Podcasts about biomarkers

Today, I'm excited to bring back the always thought-provoking Joel Greene, author of "The Immunity Code" and "The Way," for a fresh conversation on why true longevity is about so much more than how much muscle you have or the latest diet trend you're following. Joel Greene opens up about the hard lessons he's learned from decades of self-experimentation and reveals why chasing that ideal gym physique might actually backfire as you age.   Episode Timestamps: Welcome & episode introduction ... 00:00:00 The evolving nature of health and homeostasis ... 00:08:29 Beware rigid diet tribes—find nutritional flexibility ... 00:21:41 Biomarkers people miss: fasting insulin and acyl carnitines ... 00:23:11 Chronic ketosis, ATP, and metabolic slowdowns ... 00:25:16 Myth-busting muscle and the limits of bodybuilding for aging ... 00:27:17 Functional movement, flexibility, and big toe strength ... 00:34:29 Simple foundation: daily jumps or hops ... 00:47:41 Sensible protocols for muscle gain after 50 ... 01:00:07 Balance in diet as the true key to insulin sensitivity ... 01:08:06 Rules of thumb: meal timing for insulin ... 01:15:56 Stillness, faith, and feeding your spirit ... 01:21:56 Most abused supplement: Antioxidants ... 01:27:54 Body fat percentage as top longevity marker ... 01:29:12   Our Amazing Sponsors: Quantum Upgrade - Supports nervous system balance without wearables or apps—just effortless, 24/7 quantum energy streaming. With 21+ studies showing measurable improvements in stress and cellular function, it's easy to try for yourself. Visit quantumupgrade.io/NAT and use code NAT10 to start the free trial.   Blue Peptide Spray from Young Goose - Brings the message back loud and clear. With NAD+ APEX™️ to refuel energy, methylene blue to recharge your mitochondria, and GHK-Cu to tell your skin, "Hey, start making that collagen again!" It's longevity science, not cosmetic hype. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.   Mitopure® Longevity Gummies are the only clinically proven Urolithin A gummies supporting mitochondrial health — one of the key hallmarks of aging. Get 35% off a one-month subscription at Timeline.com/Nat2026 *Special deal through January 2026.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Let us know what you think! Text us!SPONSORED BY: PURE LIBERTY LABS, PRECISION WELLNESS GROUP, and THE SPECIAL FORCES FOUNDATION In this episode of Security Halt!, Deny Caballero is joined by Corey Russell and Peyton Smith, co-founders of ROE Labs, to discuss the realities of military transition, mental health, and brain health after service. The conversation explores how cumulative exposure, overpressure, and TBI affect veterans—and why research-backed supplements, education, and community support are critical during transition. Corey and Peyton share how their shared experiences led them to build a purpose-driven company focused on protecting the brain and empowering veterans to pursue new opportunities after the uniform comes off. 

What if your body has been sending you signals long before symptoms appear—and you just didn't know how to read them? In this episode of The Science of Self-Healing, we explore the power of biomarkers—the measurable clues that reveal what's happening beneath the surface of your health. From blood tests and hormones to inflammation markers, genetics, wearables, and environmental exposures, biomarkers translate the body's complex internal language into information we can understand and act on. You'll learn what biomarkers are, where they come from, why they matter when symptoms are vague or delayed, and how they're used in preventive and personalized care. We also discuss their limitations, the importance of context, and how emerging technologies are shaping the future of health monitoring. If you want to listen to your body earlier, intervene smarter, and shift from reactive medicine to a more proactive approach, this episode will change the way you think about lab tests. Tune in and learn how to read the body's early clues—before disease takes hold.

In this episode, Dr. Will Cole sits down with Geviti founder Nate Graville for an eye-opening look at how artificial intelligence, advanced diagnostics, and personalized data are reshaping the future of health. Nate shares how losing his father to cancer led him to build a platform that combines comprehensive bloodwork, wearables, and AI to help people become “default healthy.” They explore AI bias, the future of lab-on-chip technology, peptides, and the ethics of merging technology with medicine. For all links mentioned in this episode, visit www.drwillcole.com/podcast.Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors:Go to tonum.com/WILLCOLE or use code WILLCOLE for 10% off your first order.Go to Quince.com/willcole for free shipping on your order and three hundred and sixty-five-day returns. Now available in Canada! If you're ready to finally understand what your gut has been trying to tell you, ask your provider for the Gut Zoomer by Vibrant Wellness — or find a Vibrant-certified provider today at vibrant-wellness.com/willcole.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/KPN865. CME/MOC/NCPD/AAPA credit will be available until December 23, 2026.Unpacking the Latest Evidence on Biomarkers and ATTs in the Diagnosis and Management of Alzheimer's Disease: Breaking Updates From CTAD 2025 In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/KPN865. CME/MOC/NCPD/AAPA credit will be available until December 23, 2026.Unpacking the Latest Evidence on Biomarkers and ATTs in the Diagnosis and Management of Alzheimer's Disease: Breaking Updates From CTAD 2025 In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/KPN865. CME/MOC/NCPD/AAPA credit will be available until December 23, 2026.Unpacking the Latest Evidence on Biomarkers and ATTs in the Diagnosis and Management of Alzheimer's Disease: Breaking Updates From CTAD 2025 In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/KPN865. CME/MOC/NCPD/AAPA credit will be available until December 23, 2026.Unpacking the Latest Evidence on Biomarkers and ATTs in the Diagnosis and Management of Alzheimer's Disease: Breaking Updates From CTAD 2025 In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

What happens when life takes everything from you—and you're forced to decide who you become next?In this deeply moving conversation, Mark Divine sits down with Cody Lakefield, co-founder of Long Ship Men and Look Health, to explore the intersection of trauma, healing, proactive health, brotherhood, and purpose.Cody shares his journey through profound personal loss, responsibility, and suffering—and how those experiences led him to build systems that help men reclaim ownership of their health, their inner lives, and their relationships with other men.From personalized biomarker testing and preventative health… to grief, PTSD, faith, and the power of men rowing together… this episode is about moving from survival to meaning.If you're a leader, father, entrepreneur, or man navigating pressure in silence, this conversation offers a different path forward—one rooted in awareness, courage, and community.In this episode, you'll discover:Why proactive health matters more than “sick care”How understanding biomarkers gives you agency over your bodyWhy trauma doesn't resolve itself through willpower aloneThe danger of carrying everything in isolationHow brotherhood accelerates healing and resilienceWhy purpose is often forged through suffering, not comfortHow to move from surviving life to living it intentionallyJoin The Unbeatable Leader Challenge - January 13thThe Unbeatable Leader Challenge is back starting January 13th, this time we're making it FREE to join on this training. Kick off 2026 with a growth mindset to win the winner war, achieve front-sight focus, and build an unbeatable team in 2026. → https://www.unbeatableleader.comUnlock your full potential and lead with courage, clarity, and purpose—join The Unbeatable Tribe and become truly unbeatable in life and leadership.Join for free for 7 days: The Unbeatable Tribe → https://www.skool.com/unbeatable-mastery-tribe/aboutBUBS NATURALS - Use Code Unbeatable for 20% OFFI use BUBS Naturals daily for focus, recovery, and hydration—all built on a mission to honor a fallen Navy SEAL. Use code UNBEATABLE for 20% off any one time purchase or subscription at bubsnaturals.comCody Links:Website: https://www.lookhealth.com/, https://www.longshipmen.com/Book: https://a.co/d/2iDuYdy Instagram: https://www.instagram.com/raven_cody7/LinkedIn: https://www.linkedin.com/in/cody-lakevold-458b311b/?originalSubdomain=caX: https://x.com/CodyLakevoldMark Links: Website: https://markdivine.comThe Unbeatable Tribe: https://www.skool.com/unbeatable-mastery-tribe/aboutDivine Inspiration Newsletter: https://markdivine.com/newsletterYouTube: https://www.youtube.com/@markdivineofficial/Instagram: https://www.instagram.com/markdivineofficialLinkedIn: https://www.linkedin.com/in/markdivine/Facebook: https://www.facebook.com/markdivineofficial/Subscribe to https://www.youtube.com/@markdivineofficial for more inspiring conversations on leadership, growth, and impact.Rate and review the show to help us reach more listeners.Share your thoughts and takeaways in the comments!#MarkDivine #CodyLakefield #MensWork #MentalHealth #TraumaHealing #PreventativeHealth #Biomarkers #Brotherhood #PurposeDrivenLife #LeadershipDevelopment #Resilience #UnbeatableMind #LongShipTimestamps:00:00 Introduction to the Biomarkers, LookHealth, Longship Men00:38 Mark Divine's Leadership Challenge01:28 Welcome to the Mark Divine Show01:54 Introducing Cody Lakevold02:52 Cody's Health Ventures04:30 Challenges in Healthcare Access06:39 Cody's Personal Journey Begins12:38 Family Struggles and Personal Loss20:32 Coping with Family Tragedies40:31 Struggling with Nightmares and Suicidal Thoughts42:16 Turning to Alcohol for Relief43:41 Seeking Therapy and Finding Hope45:35 Discovering MDMA Therapy46:16 A Life-Changing MDMA Session53:04 Rebuilding Life and Relationships54:12 Creating Raven Lake Investments01:00:05 The Birth of Long Ship01:11:24 The Vision for Long Ship01:21:03 Conclusion and Future PlansSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Marion Moseby-Knappe talks about a prospective, international, observational biomarker study, within the Targeted Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial, to compare four markers of brain injury for the prediction of functional outcome in patients after cardiac arrest using assays that can be analysed on clinically available equipment.Click here to read the full article: https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00363-7/fulltextContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv

Microbes are awesome, says biologist Paula Welander. They have shaped Earth's chemistry and its environment over billions of years, including oxygenating the planet to make it habitable for larger life forms. In turn, microbes have been shaped by that very same environment, evolving as the climate has evolved, she says. Welander now studies the lipid membranes of ancient microbes, which can endure for millions of years, to understand this evolution and where we might be headed in the future. Microbes are our connection to the ancient world, Welander tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: ​​Paula V. WelanderConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Paula Welander, a professor of Earth Science at Stanford University.(00:04:06) Why Study Microbial LipidsWhy lipids are essential for modern microbiology and Earth's history.(00:05:19) Diversity of Microbial MembranesHow bacteria and Archaea build different kinds of membranes.(00:07:15) Reconstructing Ancient EnvironmentsUsing specific lipid biomarkers to understand the early planet.(00:09:20) Chemical Fossils vs. Organism FossilsWhy microbes don't leave traditional fossils—but their lipids do.(00:10:55) Lipids as Environmental CluesHow certain lipids indicate the environments organisms lived in.(00:12:36) Archaea: A Distinct and Ancient EntityArchaea's evolutionary importance and chemically distinct membranes.(00:15:43) The Lipid DivideWhy eukaryotic membranes resemble bacterial, not Archaeal, membranes.(00:17:12) Tracing Membrane EvolutionRecent breakthroughs in studying Archaeal lineages related to eukaryotes.(00:19:11)  Lipid Preservation Over TimeHow archaeal lipids are especially reliable as long-term biomarkers.(00:20:58) Sterols as BiomarkersThe role sterols, including cholesterol, play in lipid archeology.(00:23:14) Bacterial Cholesterol DiscoveryThe discovery that a rare bacteria can synthesize sterol precursors.(00:25:02) Functional Roles of Bacterial SterolsThe possible roles sterols may play in microbial membranes and cell function.(00:26:31) Archaea in the Human GutThe number and types of Archaea found in the human microbiome.(00:28:43) Archaea and AntibioticsWhether Archaea react similarly to bacteria when exposed to antibiotics.(00:29:46) Future In a MinuteRapid-fire Q&A: hope, research needs, and alternate career dreams.(00:31:43) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

While we cannot diagnose anxiety or depression with a single blood test, modern biomarkers can reveal the physical disruptions that influence how we think, feel, and respond to stress. From micronutrient deficiencies to inflammation, your physiology silently shapes your emotional world.Through the Ayurvedic lens of Vata imbalance and the foundational 3R Protocol, this episode shows how understanding your biomarkers can transform healing, resilience, and emotional clarity.Episode Highlights: • Why emotions have a physical foundation • The key biomarkers linked to anxiety, low mood, burnout, and fatigue • How sleep, HRV, inflammation, and nutrient reserves shape mental stability • Why replenishing deficiencies often leads to emotional breakthroughs • How to work with the body before diving into therapy or inner workIf you'd like the free checklist of mental-health biomarkers mentioned in this episode, subscribe to the newsletter at Link - https://vigneshdevraj.com/subscribe-to-newsletter/Timestamps:00:00 - 01:00: Why There Is No Single Blood Test for Emotions01:00 - 03:00: The Hidden Physical Patterns Behind Emotional Distress03:00 - 05:00: R1: Relax – Regulate the Nervous System05:00 - 06:30: R2: Reduce – Clearing Physical Overload06:30 - 08:00 R3: Replenish – Correcting Deficiencies08:00 - 09:20: Integrating BiomarkersDr Vignesh Devraj If you are interested in doing one on one Ayurvedic consultation with Dr Vignesh Devraj please find the details in this link: https://calendly.com/drvignesh/30-minute-session-with-dr-vignesh-devraj-md-ay-istIf you are economically challenged, please use the form provided to request a free Ayurvedic consultation here. (or copy paste this in your browser: https://docs.google.com/forms/d/e/1FAIpQLSd29nHcrC1RssR-6WAqWCWQWKKJo7nGcEm8ITEl2-ErcnfVEg/viewform )BALANCING THE MIGHTY VATA - ONLINE COURSE NOW AVAILABLE What makes Ayurveda unique in its treatment approach is its practical wisdom on the concept of Vata. Vata is responsible for Prana - the life energy, the nervous system - the master panel of our body, and our emotions. In Ayurveda, it is mentioned that controlling Vata is the most difficult part of healing and recovery. Recently, I have recorded a workshop on - Balancing The Mighty Vata, which has over 6 hrs of content, with notes filled with practical inputs that can be integrated into our life. You can access this at https://vigneshdevraj.com/balancing-the-mighty-vata/ For further information about Dr Vignesh Devraj, kindly visit www.vigneshdevraj.com and www.sitaramretreat.com Instagram - @sitarambeachretreat | @vigneshdevrajTwitter - @VigneshDevrajWe truly hope you are enjoying our content. Want to help us shape and grow this show faster? Leave your review and subscribe to the podcast so you'll never miss any new episodes. Thanks for your support.Disclaimer: - The content of the podcast episodes is not intended to be a substitute for professional medical procedures, consultations, diagnosis, or treatment in any manner. We strongly do not recommend using the content of these episodes as medical advice for any medical conditions for you, others, or for treating your patients.

Everyone touched by cancer knows treatments vary depending on the type of cancer. Now, with precision medicine for some cancers, treatments can be tailored to that cancer. In this podcast, Dr. James Hamrick, MD, MPH, explains what precision medicine means for cancer patients and updates listeners on developments in testicular cancer treatments. Dr. Hamrick is the chairman of the Caris Precision Oncology Alliance, known as Caris POA at Caris Life Sciences. He leads a global network of top cancer centers and research institutions dedicated to advancing precision oncology and biomarker-driven research, and he will tell us all about it. Dr. Hamrick is board-certified in internal medicine, medical oncology, and hematology. He earned his MD and MPH in epidemiology from the University of North Carolina and completed his residency and fellowship at the University of California, San Francisco.Now - back to precision medicine. Here's what Dr. Hamrick explains in the podcast.00:09:55"When we treat a cancer, it's all about hitting the cancer, the bad part, and not hurting the rest of the person. And so the more we understand the targets we should be hitting in these tumors, the better we can design treatments that hit those targets and leave the rest of the cells in a person's body alone."What does that mean? "It means fewer side effects, so more effectiveness. So when you hear precision medicine, think about this: this is where my doctor is not just treating me for cancer. Not just treating me for lung cancer, but is working to understand exactly what is driving my cancer and how can we best target that so I have the best outcome, meaning we can kill those cancer cells, right?"And the fewest side effects. That's really precision oncology. Biomarkers bio. We all know from high school biology class that the life sciences markers are the targets. So these are the targets that we can now use at Caris and other vendors. We can say, hey, that's the problem here."It's not just one testicular cell that went bad; it's one that has this certain molecular profile. So I tell patients: You should ask your doctors, Hey, what biomarkers do we care about? What is important? What are we targeting? What's valuable here?"And that's part of becoming fluent in the language of your cancer, which, as many caregivers know, is really important."Dr. Hamrick talks more about testicular cancer and the need to find genetic biomarkers for it. He explains that and related research about testicular and other types of cancer in this episode of Don't Give Up on Testicular Cancer from the Max Mallory Foundation. Links:Caris Precision Oncology Alliance - Caris POAhttps://www.carislifesciences.com/partners/caris-precision-oncology-alliance/James Hamrick, MD, MPHhttps://www.carislifesciences.com/bio/james-hamrick-md-mph/Max Mallory Foundationhttps://www.maxmalloryfoundation.comDon't Give Up on Testicular CanceSend us a textSupport the showFind us on Twitter, Instagram, Facebook & Linkedin. If you can please support our nonprofit through Patreon.

Commentary by Dr. Peter van der Meer.

Angela talks to special guest Dr Darshan Shah, M.D, about the multifaceted world of longevity and health optimisation. They delve into essential biomarkers for assessing longevity, including inflammation levels, metabolic health, and cognitive function, while emphasising the importance of a holistic approach to well-being.  Dr. Shah also discusses the complexities surrounding LDL cholesterol, the significance of lifestyle factors like exercise and diet, and the role of hormone replacement therapy for women navigating menopause KEY TAKEAWAYS: Holistic Approach to Longevity: Longevity is not just about extending lifespan but also about enhancing health-span, which includes mental, physical, and emotional well-being Individualised Assessment of LDL: LDL cholesterol levels should be interpreted in the context of individual health Importance of Lifestyle Interventions: Lifestyle factors, including regular exercise, a balanced diet rich in whole foods, adequate sleep, and stress management, are foundational for improving health and reducing the risk of chronic diseases Role of Hormone Replacement Therapy: Hormone replacement therapy can significantly benefit women during perimenopause and menopause, improving metabolic biomarkers and overall health TIMESTAMPS AND KEY TOPICS: [00:04:05] LDL cholesterol's individual impact. [00:08:14] Cardiac risk biomarkers explained. [00:10:58] Lifestyle changes for plaque reduction. [00:23:08] Midlife metabolic health strategies. [00:24:37] Glucose spikes and metabolic health. [00:32:57] Liver detoxification myths. [00:35:13] Leaky gut and gut health. [00:45:48] Early cancer detection tools VALUABLE RESOURCES ⁠Join The High Performance Health Community⁠ ⁠Click here⁠ for discounts on all the products I personally use and recommend A BIG thank you to our sponsors who make the show possible ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women's Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. CONTACT DETAILS ⁠Instagram⁠ ⁠Facebook⁠ ⁠LinkedIn⁠ Disclaimer: The High Performance Health Podcast is for general information purposes only and do not constitute the practice of professional or coaching advice and no client relationship is formed. The use of information on this podcast, or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for medical or other professional advice, diagnosis, or treatment. Users should seek the assistance of their medical doctor or other health care professional for before taking any steps to implement any of the items discussed in this podcast. This Podcast has been brought to you by Disruptive Media. ⁠https://disruptivemedia.co.uk/

Watch on YouTube → https://www.youtube.com/watch?v=VU65vnqkBmE When two of the world's leading ALS researchers meet for the first time on a podcast, something remarkable happens. Dr. Merit Cudkowicz - Tim's close friend and arguably the world's foremost ALS expert, returns to Nothing Left Unsaid for her third appearance, this time joined by Dr. Tanya Daigle from the Allen Institute, who's pioneering genetic tools that could transform how we treat neurodegenerative diseases. Together, they reveal a future for ALS research that's closer than most people realize. This isn't your typical medical conversation. Merit and Tanya speak with unguarded hope about gene therapies that have stopped disease progression in 40% of patients, AI-driven drug discovery that's accelerating at unprecedented rates, and precision targeting tools that could deliver treatments directly to dying motor neurons without invasive brain surgery. They discuss the real bottlenecks between laboratory breakthroughs and patient impact, why most ALS drug trials aren't actually failures, and how the field has evolved from a handful of researchers to a global collaborative effort spanning continents. CHAPTERS: 00:00 Trailer01:09 Intro02:55 Current State of ALS Research05:19 Misconceptions About ALS09:32 Progress and Future of ALS Treatments21:17 Innovations in Genetic Tools for ALS31:59 A New Frontier in ALS Research35:03 Efficiency of Platform Trials in ALS Research36:59 The Importance of Funding and Science Collaboration37:55 Advancements in Treating ALS Smarter38:52 The Role of Biomarkers and Individualized Therapies41:31 Dream Trials and Future Prospects48:01 The Impact of AI in ALS Research54:08 The Next Big Pivot in ALS Research58:18 Hope and Collaboration in ALS Research01:01:04 How to Be Part of ALS Community RESOURCES & LINKS: Allen Institute: https://alleninstitute.orgHealey & AMG Center for ALS at Mass General: https://www.massgeneral.org/neurology/als SPONSORS:ElevenLabs: Thanks to ElevenLabs (https://elevenlabs.io) for supporting this episode and powering Tim's voice. SOCIAL:Website: https://nlupod.com/X: https://x.com/nlutimgreenFacebook: https://www.facebook.com/NLUpodInstagram: https://www.instagram.com/nlupod LISTEN ON OTHER PLATFORMS: Apple Podcasts: https://podcasts.apple.com/us/podcast/nothing-left-unsaid/id1734094890Audible: https://www.audible.com/podcast/Nothing-Left-Unsaid/B0CWTCRKGZCastbox: https://castbox.fm/channel/id6405921?country=usOvercast: https://overcast.fm/itunes1734094890iHeartRadio: https://www.iheart.com/podcast/263-nothing-left-unsaid-155769998/ PERSONAL: Tackle ALS: https://www.tackleals.comTim Green Books: https://authortimgreen.comTim's New Book - ROCKET ARM: https://www.amazon.com/dp/0062796895/ Learn more about your ad choices. Visit megaphone.fm/adchoices

In an era where health insights are becoming increasingly personalized, it is always inspiring to meet innovators like Jason Moore who are pushing the boundaries and expanding resources. Jason is the CEO and founder of Spren, a cutting-edge platform that uses smartphone-based tech to measure body composition, HRV, and metabolic signals – all while providing personalized nutrition and 24/7 AI coaching. For the past eleven years, Jason has immersed himself in the world of biomarkers, dedicating his career to making advanced physiological insights accessible to everyday users. As a self-described "aggressive learner", Jason is passionate about solving complex health problems through science, innovation, and a team of world-class researchers… This discussion outlines: What digital biomarkers actually are and why they're transforming modern health and performance tracking. Why HRV is considered the most comprehensive biomarker for overall well-being, resilience, and stress response. How advanced body composition analysis works using only a smartphone. Whether you're a fitness coach, daily gym-goer, or someone curious about optimizing your health, this conversation offers a deep dive into the tech reshaping how we measure human performance. You can connect with Jason by following him on Instagram and LinkedIn!

ChairProfessor Yoshikatsu EtoAdvanced Clinical Research Center, Southern Tohoku Research Center for Neuroscience, Tokyo, JapanSpeakersDr Nicole Muschol International Center for Lysosomal Disorders (ICLD), University Medical Center, Hamburg-Eppendorf, GermanyProfessor Patrício AguiarInborn Errors of Metabolism Reference Center, Unidade Local de Saúde de Santa Maria / Faculty of Medicine, Lisbon University, PortugalDr Robert HopkinCincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USAProfessor Yoshikatsu EtoWelcome to the Chiesi symposium. The title of this symposium, Catching the Clues, Changing the Cause of Lysosomal Storage Disease: Illuminating Complex Pathway of Rare Disease with Fabry Disease, Alpha-Mannosidosis, in Focus.This is a disclaimer: Following discussion does not focus on or depict any specific products manufactured by any pharmaceutical company. Patient cases are for medical discussion only and reflect the faculty own experience. They represent a typical clinical scenario. This presentation in part and whole may not be reproduced and not copy and not recording.I'm Dr. Eto from Tokyo, Japan, and the three distinguished speakers: Dr. Nicole Muschol from Germany, Eppendorf University. Professor Aguiar, the Portuguese, The Inborn Errors of Metabolism Reference Center, and also Professor Robert Hopkin, Cincinnati Children's Hospital, United States.The purpose of this symposium: Explore the patient journey across the LSD continuum, focusing on the unmet needs and diagnosis, and treatment initiation, and long-term management, and utilize case-based discussion focused on Alpha-mannosidosis, Fabry disease to highlight disease-specific challenges. Access where challenge persist in patient journey, and where tailored intervention can improve outcomes.Introduction of LSD patient journey with a spotlight on Fabry disease, Alpha-mannosidosis. Challenge to the diagnosis and then treatment and monitoring. Common LSD challenges over the patient journey, as shown here, and at least more than 70 different lysosomal diseases known. Incidence is about 1:5,000-1:8,000 in newborn. In the literature, much higher incidence.Multi-organ manifestation in many organ involved, and clinical heterogeneity are very complicated. The new screen method has been established already. Identify patient presymptomatically. That important by the newborn screening, something like that, early treatment essential. After the diagnosis treatment start, early and the presymptomatic treatment initiation, and usually delayed diagnosis, delayed treatment. Perceived burden of treatment may delay treatment start in patient milder form. Milder form is very difficult in the many cases, and particularly for Fabry disease also.After the treatment start and then monitoring, as you know, we discussed about the monitoring rely on the combination of clinical assessment, laboratory test, biomarkers, and imaging, and several other factors. Biomarkers and ADA drug assay lack standardization. Actually, the Alpha, and Beta, or [inaudible 00:03:19] Fabry disease, different ADA-titled measurement. Also, the patient experience between clinical visit, ERT infusion is under-reported.We discuss today two topics, two disease. Alpha-mannosidosis is very rare. In Japan, only few cases, and caused by the deficiency of Alpha-mannosidase, an accumulation of mannose-rich oligosaccharides and inheritance of autosomal-recessive. Age of onset is a very early period and younger period, adult period. Incidence approximately is very rare, 1:500,000.There are diseases we don't know exactly. If you have a treatment, maybe your incidence is much increased, and severe or attenuated [inaudible 00:04:09]. Alpha-mannosidosis is still a new disorder, and must differentiate from Mucopolysaccharidosis.On the other hand, the Fabry disease I think is very common. There are many discussion already in the past 20 years. Deficiency of a-Gal A, accumulation of Gb3⁵­­ or Lyso-Gb3, many other glycoprotein, which a terminal of a-Gal A, and X-chromosome. This is very important X-chromosomal inheritance. In case of this, and usually, female does not affect, but in case of Fabry, more of female also involved.First symptom, imagine at any age. Then incidence about 1:40,000-1:60,000. But depending on the country, as you know, classical form, about 1:40,000. Recently, after the newborn screening, late onset, very high incidence. About 90% of it—actually, we carried out a newborn screening in Japan—90% are late onset. But the clinical variety, so many clinical varieties, so incidents here, 1:3,000-1:4,000, something like that. Now, using the Alpha-mannosidosis and Fabry disease as an illustrative example, we will explore these disorders.

In this podcast episode, Emma Sutherland speaks with Dr Nick Fuller, Clinical Trials Director at the Royal Prince Alfred Hospital Endocrinology Department and researcher at the Charles Perkins Centre. Together they unpack the complex physiology behind weight regain, including metabolic adaptation, appetite-hormone shifts, and the evolutionary mechanisms that make long-term weight loss so challenging. Dr Fuller explains how even small amounts of weight loss can trigger significant biological compensations, why traditional dieting approaches often fail, and how interval-based weight management can help prevent the rebound effect commonly seen in clinical practice. The discussion also explores emotional eating, circadian influences on hunger, and the importance of balanced meals, sleep routines, daily activity, and a whole-foods approach to support metabolic health. This episode provides practitioners with a grounded, evidence-informed lens for guiding patients through sustainable, long-term weight change. COVERED IN THIS EPISODE (01:04) Welcome Dr Nick Fuller (01:46) The Charles Perkins Centre (02:52) Prevalence of successful weight loss (05:59) The evolutionary mismatch (12:30) Compensatory methods of weight loss (16:50) Inflammation and obesity (19:35) Biomarkers (22:14) Probiotic therapy (24:51) Weight regain in menopause (28:25) Matador study (34:12) Protein recommendation (38:17) Dopamine hunt (41:15) Weight loss medications (44:05) Patterns found in successful weight loss (49:52) Final remarks Find today's transcript and show notes here: https://www.bioceuticals.com.au/education/podcasts/the-biology-of-sustainable-weight-loss Sign up for our monthly newsletter for the latest exclusive clinical tools, articles, and infographics: www.bioceuticals.com.au/signup/ DISCLAIMER: The information provided on fx Medicine by BioCeuticals is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.

Is your wife or fiancée interested in using natural family planning or a fertility awareness method? If so, this episode is a basic introduction of :how fertility awareness methods functionhow effective they are for family planninghow you can participate in the learning process and beyond one method worth exploring due to its effectiveness and health benefits. (Women interested in using NFP or FABM -- send this episode on to the man in your life who you'd like to introduce to the topic!)NOTE: This episode is appropriate for all audiences.OTHER EPISODES YOU MIGHT LIKE:Ep. 34: Is Contraception a Faithful Choice for Christians?Ep. 67: For Men: How & Why Your Creighton Participation MattersEp. 17: Client Story - Kadie & EthanSend us a textSupport the showOther great ways to connect with Woven Natural Fertility Care: Learn the Creighton Model System with us! Register here! Get our monthly newsletter: Get the updates! Chat about issues of fertility + faith: Substack Follow us on Instagram: @wovenfertility Watch our episodes on YouTube: @wovenfertility Love the content? The biggest gift you could give is to click a 5 star review and write why it was so meaningful! This podcast is provided for educational and informational purposes only and does not constitute providing medical advice or professional services. The information provided should not be used for diagnosing or treating a health problem or disease, and those seeking personal medical advice should consult with a licensed physician. Always seek the advice of your doctor or other qualified health provider regarding a medical condition. If you think you may have a medical emergency, call 911 or go to the nearest emergency room immediately. Neither Woven nor its staff, nor any contributor to this podcast, makes any represe...

The mortality and economic burden of drug induced acute kidney injury are substantial, emphasizing the need for prevention and optimal treatment. Dr. Sandra Kane-Gill provides perspective on novel kidney biomarkers and how they offer a missing piece of the assessment for early detection and management of DI-AKI. Read the full manuscript at: https://accpjournals.onlinelibrary.wiley.com/doi/full/10.1002/phar.70071

Short Summary: Dr. Holly Helbig and Dr. David Levine describe how they use SAA and other biomarkers to spot infection early, guide treatment, support biosecurity, and monitor horses in real time.Landing page copy: Acute phase proteins such as serum amyloid A (SAA) give veterinarians an early look at inflammation, infection, and how a horse responds to treatment. In this Equine Innovators episode, we dig into how SAA and other key biomarkers guide everyday decisions—from biosecurity on busy farms and showgrounds to managing postoperative cases, colic, and foal exams.Host Stephanie Church, editorial director at The Horse, talks with Dr. Holly Helbig of Zoetis and Dr. David Levine from the University of Pennsylvania's New Bolton Center about when they reach for SAA, how it compares with fibrinogen and white blood cell counts, and why serial testing often matters more than any single number. They share stall-side and hospital protocols, real-world case examples, and ways biomarker trends support smarter antimicrobial use and quarantine decisions.In this episode, Drs. Helbig and Levine discuss:What acute phase proteins are and how SAA reflects early inflammation in horsesHow fast SAA and fibrinogen rise and fall, and how that timing shapes testing plansWhen stallside SAA testing shines in ambulatory practice, at horse shows, and on the farmUsing SAA to help sort out joint flares vs. septic joints and guide post-surgical monitoringPractical cutoffs and patterns for foals, including how vaccination and IV plasma affect SAAWhere SAA fits into antimicrobial stewardship and cost-conscious biosecurity strategiesEmerging research and what might come next for biomarkers in equine practiceTune in to hear how two equine veterinarians lean on SAA and other biomarkers to clarify tough calls, support horse owners, and keep diagnostics and treatments on the right track.GUESTS AND LINKS – EPISODE 23:Host: Stephanie L. Church, editorial director at The Horse: Your Guide to Equine Health Care/TheHorse.com | @stephlchurch on Instagram | Email Stephanie (schurch@thehorse.com)Links: (SAA and other Biomarker resources from TheHorse.com) SAA: A Magic 8 Ball for Detecting Infection in Horses?, SAA: Infection Detection in Horses (Infographic), SAA Measurements Can Help Detect Surgical Implant Infection, Advances in Equine Infectious Disease DetectionGuest: Holly Helbig, DVM, joined Zoetis in 2023 as an equine technical services veterinarian. She is a graduate of The Ohio State University with a focus in lameness and sport horse medicine. Helbig was the official veterinarian for The World Equestrian Center Ohio; The Kentucky Horse Shows series; and various FEI competitions for 10 years prior to joining Zoetis. She also had an ambulatory practice serving patients...

Topics We Cover: 00:00 – New data from Harvard/Mass General may classify nearly 70% of adults as having obesity 03:00 – A new oral triple agonist shows record-setting absorption rates 07:00 – Fractal Health's Revita procedure: weight maintenance after stopping GLP-1s 12:00 – Zepbound vial prices drop (full breakdown by dose) 16:00 – Dave's personal experience switching off Mounjaro and intense hunger return 22:00 – Novo Nordisk's EVOKE/EVOKE+ Alzheimer's trial: what the data really means 29:00 – Why GLP-1 neurological research is just getting started 33:00 – Updates on access, partners, and major news coming soon for Medicare patients If you're on Wegovy, Mounjaro, Zepbound, Saxenda, Trulicity, or compounded versions, this episode gives you the insight and context you need to have more competent and confident conversations with your doctor. Bullet Point Summary of the Podcast Episode New Obesity Measurement Data (Harvard/Mass General Study) Harvard and Mass General propose adding waist circumference to BMI to better diagnose obesity. Traditional BMI misses key factors like muscle mass and body composition. Using the updated measure, Americans classified as obese jumps from ~43% to almost 69%. This means 7 out of 10 U.S. adults would now qualify as having the disease of obesity. Dave notes this validates many people who “feel” metabolically unwell despite a “normal” BMI. Reinforces his claim that “most people should be talking to their doctors about GLP-1s.” New Oral Triple Agonist (Ascletis – ASC41/ASC? Molecule) From Ascletis (A-S-C-L-E-T-I-S), developing an oral triple agonist targeting: GLP-1 GIP Glucagon Similar in mechanism to retatrutide, expected around 2027. Preclinical (animal) data show stunning results: Oral bioavailability of 4.2% 9× higher than tirzepatide 30× higher than oral semaglutide 6× higher than oral retatrutide 57× greater drug exposure than oral retatrutide Half-life ~56 hours Stronger receptor activation than retatrutide in vitro Suggests potential for the first powerful oral triple agonist—worth watching. ️ 3. Discussion of the Gray Market / TikTok Experience Dave briefly recounts losing his TikTok account and landing in an algorithm filled with teenagers promoting gray-market “retatrutide.” Expresses concern over unregulated peptide sales, especially to minors. Fractal Health's New Data – Weight Maintenance After Stopping GLP-1s New results from the Reveal One study (Fractal Health). Participants: lost 24% of body weight on GLP-1s → stopped injections → got one Revita procedure. At 6 months post-GLP-1 discontinuation: Weight changed only 1.5% (vs. ~10% regain in typical off-drug trials) HbA1c barely shifted Safety profile clean Suggests possible long-term weight maintenance without injections through gut mucosal re-lining. Dave describes his own recent attempt to switch drugs and significant hunger return. Food Noise & Biologic Hunger Dave discusses how stopping Mounjaro caused terrifying, primal hunger. Describes the distinction between: Food noise (brain-based thoughts) Hunger signals (biological/animalistic) Reinforces why many patients cannot maintain weight loss without support. Zepbound (Tirzepatide) Cash-Pay Price Reductions Eli Lilly drops cash-pay vial pricing: 2.5 mg: $349 → $299 5 mg: $499 → $399 7.5–15 mg: $499 → $449 Community feedback (informal poll): Most say still too high to leave compounded versions. Many would switch to branded if price hit $200–$300. Dave notes the Most Favored Nations agreement will push GLP-1 prices toward $250/month within 24 months. Alzheimer's Study (Novo Nordisk – EVOKE & EVOKE+) Oral semaglutide (Rybelsus, 14 mg) did not slow Alzheimer's clinical progression. Biomarkers improved but daily function and cognitive decline did not improve vs placebo. Important context: Oral Rybelsus is a weak form of semaglutide; stronger versions (like Wegovy 2.4 mg or upcoming high-dose oral Wegovy) not tested. Weight loss is not desirable in Alzheimer's patients, influencing drug selection. Dave emphasizes: This was a nearly $700M trial and an act of scientific courage. This is NOT the end of GLP-1 Alzheimer's research. Future molecules may target neurological pathways without suppressing appetite. Mentions Lilly's brenipatide, a GIP receptor agonist being developed for: Addiction Opioid dependency Possibly asthma ️ 8. Access, Cost, and Patient Empowerment Highlights Shed as a partner offering telehealth GLP-1 access. Notes many patients hide GLP-1 use from their primary care doctors. Reinforces OTP's mission: better, more honest conversations with clinicians. Shapa (Numberless Scale) & Dave's Personal Update Dave explains how the Shapa numberless scale helped him stay engaged during weight fluctuations. Finds stepping on “zones” (green/gray/blue) less emotionally damaging than numbers. Closing Notes Promises upcoming Eli Lilly savings card update. Encourages subscribing, liking, and enabling notifications for algorithm visibility. Thanks OTP community for amplifying patient-centric obesity medicine news. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Short Summary: Dr. Holly Helbig and Dr. David Levine describe how they use SAA and other biomarkers to spot infection early, guide treatment, support biosecurity, and monitor horses in real time.Landing page copy: Acute phase proteins such as serum amyloid A (SAA) give veterinarians an early look at inflammation, infection, and how a horse responds to treatment. In this Equine Innovators episode, we dig into how SAA and other key biomarkers guide everyday decisions—from biosecurity on busy farms and showgrounds to managing postoperative cases, colic, and foal exams.Host Stephanie Church, editorial director at The Horse, talks with Dr. Holly Helbig of Zoetis and Dr. David Levine from the University of Pennsylvania's New Bolton Center about when they reach for SAA, how it compares with fibrinogen and white blood cell counts, and why serial testing often matters more than any single number. They share stall-side and hospital protocols, real-world case examples, and ways biomarker trends support smarter antimicrobial use and quarantine decisions.In this episode, Drs. Helbig and Levine discuss:What acute phase proteins are and how SAA reflects early inflammation in horsesHow fast SAA and fibrinogen rise and fall, and how that timing shapes testing plansWhen stallside SAA testing shines in ambulatory practice, at horse shows, and on the farmUsing SAA to help sort out joint flares vs. septic joints and guide post-surgical monitoringPractical cutoffs and patterns for foals, including how vaccination and IV plasma affect SAAWhere SAA fits into antimicrobial stewardship and cost-conscious biosecurity strategiesEmerging research and what might come next for biomarkers in equine practiceTune in to hear how two equine veterinarians lean on SAA and other biomarkers to clarify tough calls, support horse owners, and keep diagnostics and treatments on the right track.GUESTS AND LINKS – EPISODE 23:Host: Stephanie L. Church, editorial director at The Horse: Your Guide to Equine Health Care/TheHorse.com | @stephlchurch on Instagram | Email Stephanie (schurch@thehorse.com)Links: (SAA and other Biomarker resources from TheHorse.com) SAA: A Magic 8 Ball for Detecting Infection in Horses?, SAA: Infection Detection in Horses (Infographic), SAA Measurements Can Help Detect Surgical Implant Infection, Advances in Equine Infectious Disease DetectionGuest: Holly Helbig, DVM, joined Zoetis in 2023 as an equine technical services veterinarian. She is a graduate of The Ohio State University with a focus in lameness and sport horse medicine. Helbig was the official veterinarian for The World Equestrian Center Ohio; The Kentucky Horse Shows series; and various FEI competitions for 10 years prior to joining Zoetis. She also had an ambulatory practice serving patients...

Krista Casazza talks about validating key biomarkers in Niemann-Pick type C and why they are essential for future clinical trials and regulatory approval. The discussion focuses on emerging candidates such as 24-hydroxycholesterol, neurofilament light chain, and calbindin-D, alongside the urgent need for data harmonisation and collaboration across the NPC community. Biomarker Validation in NPC1: Foundations for Clinical Trials and Regulatory Alignment Krista Casazza, et al https://doi.org/10.1002/jimd.70075

BrainStorm wants to hear from you! Send us a text.Ep 99: The Future of Alzheimer's Trials: AI, Biomarkers, and Remote Research – John Dwyer, CEO of The Global Alzheimer's PlatformIn part 2 John Dwyer, CEO of the Global Alzheimer's Platform (GAP), and BrainStorm host Meryl Comer discuss transforming Alzheimer's research and clinical trials. Dwyer shares how the field is shifting toward earlier intervention and leveraging artificial intelligence to improve trial efficiency and accuracy. AI can help identify subtle disease patterns and ensure trials enroll appropriate candidates. GAP is also pioneering remote, decentralized trials that bring research into patients' homes rather than requiring frequent clinic visits, aiming to dramatically scale up participation.Dwyer also highlights proven lifestyle interventions that support cognitive health alongside pharmaceutical treatments and suggests multiple treatment approaches may soon be available.This episode of BrainStorm is sponsored by Johnson & JohnsonSupport the show

This week, Linda sits down with renowned molecular biologist Dr. Bill Andrews, one of the world's leading researchers on telomeres and human longevity. Dr. Andrews has dedicated over 30 years to understanding why we age—and how we might stop or even reverse the process. In this powerful conversation, he breaks down what telomeres really do, why they shorten, and what current science can (and cannot) promise when it comes to living longer, healthier lives. He also discusses Televital, the only supplement he says has been shown to induce telomerase, and why true age reversal still requires large-scale gene therapy research. If you want a grounded, science-driven look at longevity without the hype, this is an episode you'll want to hear. What Linda Talks About With Dr. Andrews What telomeres are and why they control how long our cells live Why shortening telomeres is the real driver of aging What telomerase is and why activating it matters The difference between slowing aging and reversing aging Why most "anti-aging" products only change biomarkers—not true aging The "tug-of-war" analogy that explains how telomere length changes How Televital compares to other supplements Why gene therapy may be the key to true age reversal How much research funding is needed to move longevity science forward Why some aging claims sound promising but fail the "Betty White Test" Why Dr. Andrews believes real age reversal is possible in our lifetime Main Topics Covered Understanding the Cellular Clock of Aging Dr. Andrews explains how every cell in the body loses a bit of its telomeres each time it divides. When telomeres get too short, cells can no longer replicate—and this is a major reason we age. The Telomerase Breakthrough He clarifies why the only way to actually lengthen telomeres is through telomerase activation, and why most supplements claiming to do this simply cannot. Why Slowing Telomere Shortening Still Matters Even if something cannot reverse aging, slowing the rate of cellular decline can still have meaningful long-term impact. Dr. Andrews explains why Televital is the only supplement shown to induce telomerase, and how it affects the "tug-of-war" between shortening and lengthening. Biomarkers vs. True Reversal From DNA methylation to glycosylation, many companies claim "reversed aging" based on biomarkers. Dr. Andrews outlines why these measurements don't mean actual age reversal—and what real reversal would require. The Betty White Test Dr. Andrews' signature test: if a product truly reverses aging, you should visibly look, feel, and function like you did decades earlier—not just change lab numbers. Gene Therapy: The Future of Longevity He discusses ongoing efforts to develop gene therapy capable of fully restoring telomerase to adult cells—and why he believes it's possible within the next few years with adequate research funding. The Company Bringing His Research to Market Dr. Andrews explains why he partnered with Touchstone Essentials to launch Televital and praises their commitment to health-first product development rather than profit margins. He also highlights other Touchstone Essentials products including: Glucocontrol (converts sugar into fiber) Zeolite-based detox products for heavy metals and toxins Fulvic acid (the active component of shilajit) Where to Find the Product Dr. Andrews Recommends Televital & Touchstone Essentials: https://thegoodinside.com  

Did you know that the prevalence of acquired ESR1 mutations increases after exposure to endocrine therapy? Credit available for this activity expires: 11/26/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/advancing-copd-care-through-precision-medicine-and-patient-2025a1000x00?ecd=bdc_podcast_libsyn_mscpedu

Today I'm joined by Henry O'Connell, CEO & Founder of Canary Speech, the company pioneering AI-powered vocal biomarkers to detect diseases like Alzheimer's, Parkinson's, and other neurological and behavioural conditions, all through a 20–30 second voice sample.In this episode, we explore:How Canary Speech was founded and where the idea came fromWhy holding 14 patents in vocal biomarker technology is such a competitive advantageHow Canary ensures clinical-grade safety, trust, and bias mitigation in AI healthcare toolsThe latest innovations in aggression detection, neurological disorders & behavioural healthHow global regulation (U.S. vs Europe vs Asia) shapes adoption speed in healthcare AIIf you're interested in AI, healthcare, digital biomarkers, clinical innovation, or the future of diagnostics, this episode is a must-listen.

In this episode of the Dementia Researcher - Xxplored Women's Brain Health podcast, host Dr Laura Stankeviciute speaks with Professor Claudia Barth from Charite University and Dr Gillian Coughlan from Harvard Medical School to examine the midlife transition, menopause and its significance for women's brain health. Together they outline what the menopause truly involves across the early, late, and post stages, and explain how hormonal change affects brain structure, energy use, mood, and cognition. They also explore why this period may coincide with greater vulnerability to later Alzheimer's disease and discuss the role of early or surgical menopause, symptom severity, and gaps in existing research cohorts. The episode highlights the need for richer reproductive data, real time biomarker studies, and closer collaboration with digital health tools to better capture women's lived experiences. It reflects a growing wave of research and public interest aimed at improving understanding, support, and evidence based care during this important life stage. -- Takeaways ● Menopause is a long transition shaped by fluctuating hormones. ● Cognitive and mood symptoms reflect changes in brain networks. ● Earlier menopause is linked with increased later Alzheimer's risk. ● Major research cohorts lack detailed reproductive data. ● New real time studies are beginning to track symptoms and biomarkers. ● Digital tools will be key for future research. ● Better global representation is needed across studies. ● Momentum is building to close long standing gaps in women's health. -- Find bios on all our speakers, a full transcript of the show and more on our website at https://www.dementiaresearcher.nihr.ac.uk - Follow us on social media: https://www.instagram.com/dementia_researcher/ https://www.facebook.com/Dementia.Researcher/ https://www.twitter.com/demrescommunity https://www.linkedin.com/company/dementia-researcher https://www.bsky.app/profile/dementiare…archer.bsky.social -- Download and Register with our Community App: https://www.onelink.to/dementiaresearcher -- Chapters 00:00 Introduction to Menopause and Research Focus 07:25 Understanding Menopause: Definitions and Stages 16:27 Menopause and Alzheimer's Disease: A Critical Connection 22:43 Understanding Menopause and Brain Health 25:21 Historical Blind Spots in Alzheimer's Research 26:38 The Importance of Reproductive Variables 31:46 Biomarkers and Methodologies in Women's Health Research 35:28 Industry Collaboration in Research 39:00 Personal Reflections on Women's Brain Health

Send us a textWelcome to episode 1 of our series- IBD Can Eat Me guest hosted by Stacey Collins, IBD RD. In this series, Stacey will interview other Dietitians who also specialize in IBD. This week we welcomed Venus Kalami- board-certified pediatric Dietitian Nutritionist! What if the strict diet you're told to follow does more harm than good? We sit down with pediatric dietitian Venus to unpack how nutrition in IBD can support health without sacrificing joy, culture, or family life. From Stanford Children's IBD and celiac center to medical affairs and public education, Venus brings a rare mix of clinical depth and human warmth—and she doesn't shy away from hard truths.We dig into the pressure families feel to “do everything,” the overuse of restrictive therapeutic diets, and the real risks that come with them: malnutrition, ARFID, pediatric feeding disorders, and lasting food trauma. Venus shares a clear way to tell the difference between a transient food reaction and an inflammatory flare, helping patients step off the rollercoaster of fear and over-correction. She also shows how to make care culturally inclusive with simple, powerful questions: What do you like? What do you cook? What feels doable at home? It's a move from generic handouts to plans that honor heritage foods and real life.You'll hear a vivid case study where a patient referred for low FODMAP improved dramatically without elimination—just lactase with dairy, spreading fruit across the day, and changing other patterns developed from past food trauma. We talk about involving mental health early, “asking around the ask” when supplements come up, and borrowing pediatric best practices for adults who shouldn't have to navigate IBD alone. The theme running through it all: patients deserve permission to dream beyond survival. Biomarkers matter, but so do birthdays, travel, and the comfort foods that make you feel at home.If this conversation resonates, follow the show, share it with someone who needs a gentler path, and leave a review to help more people find evidence-based, humane IBD care. Your feedback shapes future episodes—what question should we tackle next?Nutrition Pearls podcast with VenusVenus on XSolid Starts app"Offering Nutritional Therapies to Patients with IBD: Even If You're Not An Expert"- Video from Nutritional Therapy for IBDLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!

JACC's November 25, 2025 issue kicks off Thanksgiving week with JACC Editor-in-Chief Harlan M. Krumholz, MD, SM, reflecting on his editor's page and the day he became a doctor (0:12).  For original research articles, he discusses a study on colchicine & clonal hematopoiesis, an exploratory study of the LoDoCo2 trial (1:10), and a paired editorial comment with more perspectives and a reminder of the upcoming COLCOT trial (4:33). Next, a study on Lp(a) and IL-6 (4:54) and an editorial (6:12), 30-year CVD risk percentiles based on the PREVENT equations (6:30), and an accompanying editorial from JACC Deputy Editor Erica Spatz, MD, on next-generation strategies to encourage healthier behaviors (7:35).  Other studies and editorials include a fascinating look at alcohol and blood pressure (8:04) and reinforcing the WHO public health guidance (10:05); remnant cholesterol in young adults (10:38) and implications for cholesterol guidelines (12:36). We also include four brief reports on RSV vaccine (13:11), long Covid (13:43), Lp(a) levels (14:06), the predictive power of polygenic risk scores (14:58), a viewpoint on US veterans (15:36), and our regular Amara Yad image (15:53), which we're delighted to be able to continue to promote with JACC: Clinical Electrophysiology Editor-in-Chief Kalyanam Shivkumar, MD.  

Today, I'm joined by the inspiring Dr. Darshan Shah, a board-certified surgeon who made the bold leap from the operating room to the forefront of longevity and functional medicine. In our conversation, Dr. Shah opens up about his own journey through burnout, chronic illness, and autoimmune disease, and shares how simple, consistent lifestyle changes became the real medicine that transformed his health. His experience revealed firsthand just how powerful habits like movement, proper nutrition, and sleep can be—often succeeding where surgery and prescriptions fell short.   Episode Timestamps: Intro and offers ... 00:00:00 Dr. Darshan Shah's journey from surgery to lifestyle medicine ... 00:04:37 Simple actions: nutrition, movement, habit formation ... 00:08:41 Challenges of doctors embracing lifestyle changes ... 00:11:06 Building a parallel system: prevention and chronic care ... 00:14:32 Empowering patients: tech, wearables, and AI ... 00:18:27 Therapeutic plasma exchange (TPE): mechanism and safety ... 00:27:47 Essential biomarker and at-home tests ... 00:48:19 Continuous glucose monitors and real-time health feedback ... 00:52:33 Next Health model: prevention, functional, lifestyle, longevity ... 00:43:08 Longevity circuit: cellular gym approach ... 00:59:37 Liquid biopsy and early cancer detection ... 01:02:08 Advice for health, self-care, and lifelong vitality ... 01:09:31 Where to learn more and clinic expansion ... 01:10:26   Our Amazing Sponsors: Manukora honey - From remote forests in New Zealand, where bees collect nectar from the native Manuka tea tree. That nectar is naturally rich in antibacterial compounds like MGO, plus antioxidants and prebiotics that support immunity and gut health. Visit manukora.com/NAT to save up to 31% plus $25 worth of free gifts with the Starter Kit - you'll get an MGO 850+ Manuka Honey jar, 5 travel sticks, a wooden spoon, and a guidebook. *Look out for their Black Friday/Cyber Monday promotion from 11/17/25 - 12/02/25..   Qualia NAD+ - A groundbreaking, doctor-formulated vegan formula that boosts your NAD levels by up to 67% for enhanced cellular energy, DNA repair, and detox support. Go to qualialife.com/NATHALIE  and use promo code NATHALIE to get 15% off—and try it risk-free with their 100-day money-back guarantee.   Probiotic Breakthrough by Bioptimizers - uses a stress-tested Lactobacillus plantarum strain that showed over 30× greater survival in bile and intestinal fluid vs. generic strains. Save 15% at bioptimizers.com/bionat and use code BIONAT for 15% off any order. Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/EBAC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/APF865. CME/EBAC/AAPA/IPCE credit will be available until November 21, 2026.Nuclear Medicine for Alzheimer's Disease in the Hot Seat: Case Conference on Advancing Early Diagnosis With PET Imaging and Biomarkers In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/EBAC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/APF865. CME/EBAC/AAPA/IPCE credit will be available until November 21, 2026.Nuclear Medicine for Alzheimer's Disease in the Hot Seat: Case Conference on Advancing Early Diagnosis With PET Imaging and Biomarkers In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

HOUR 1 Hour 1 of Rush to Reason ignites Health & Wellness Wednesday with Dr. Scott Faulkner, owner of Castle Rock Regenerative Healthcare (https://castlerockregenerativehealth.com), stepping in for John Rush. He's joined by biohacker and high-performance health strategist Jeremy Sova, whose dramatic personal transformation has placed him just one degree from today's top longevity pioneers. But can the cutting edge of biohacking really help you reverse aging, sharpen performance, and even conquer brutal long-haul jet lag? Together, Dr. Scott and Jeremy unpack the radical experiments of tech mogul Brian Johnson—the Braintree/Venmo creator turned full-time anti-aging test case. What happens when someone pours millions into biomarker testing, optimal equipment, and scientific rigor? And more importantly: What lessons can normal people take from the world's most advanced N=1 experiment? Listeners get a fast-paced look at VO₂ max, circadian rhythm, biological age, healthspan vs. lifespan, and Jeremy's evidence-based jet-lag protocol used by world travelers and peak performers. Then Dr. Scott drops a major reveal: a new generation of sublingual peptides—no injections, no needles—thin dissolvable strips that bypass the liver for dramatic absorption and game-changing results. HOUR 2 Hour 2 of https://RushToReason.com dives even deeper into the world of high-performance health as Dr. Scott continues the conversation with biohacking expert Jeremy Sova. But this hour isn't just about supplements or trends—it's about asking the question too many people avoid: How well do you actually know what's happening inside your body? From the dangers of taking the wrong supplements to the power of 110-plus biomarker panels, Dr. Scott and Jeremy reveal why fundamental transformation starts with data—not guesswork. What hidden issues could your basic labs be missing? And how much faster could you reclaim energy, metabolism, and longevity with targeted optimization instead of chasing fads? A caller sparks a fascinating discussion on sunlight, circadian rhythm, vitamin D, seasonal affective disorder, and the rising field of red-light therapy. Could light itself be one of the most underrated health tools of our generation? Then Dr. Scott unveils major news: Castle Rock Regenerative Healthcare is expanding—bringing in a new -170°F electric cryotherapy chamber, DaVinci EWOT systems, and CAROL REHIT bikes designed to supercharge VO₂ max, muscle mass, and healthy aging. HOUR 3 Hour 3 of Rush to Reason explodes into one of the most forward-thinking conversations in modern longevity as Dr. Scott, continues with biohacker Jeremy Sova to unveil the next wave of regenerative medicine. The hour opens with a deep dive into plasmapheresis—a therapy powerful enough to lower inflammatory cytokines, reset the immune system, reverse biological age, and even remove PFAS “forever chemicals.” But why are only 20 people being offered a one-time, dramatically discounted launch? And what does this treatment mean for young women preparing for pregnancy… or biohackers chasing optimal health? From there, the conversation sharpens: How dangerous are the microplastics and toxins we're unknowingly passing on to the next generation? Can Quest biomarker panels reveal hidden immune threats before symptoms appear? And what happens when you finally have a treatment that can remove those chemicals instead of just worrying about them? Then Dr. Scott shifts gears—and shocks listeners—with his personal experience using next-generation stem cell blends for hair regrowth and joint repair. Jeremy adds his own proof-of-concept story with the HOCATT ozone sauna, boosting immunity so powerfully that even a 103° fever couldn't take him down. Tune in to find out how different your future might look if you started on a new health journey now?

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/EBAC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/APF865. CME/EBAC/AAPA/IPCE credit will be available until November 21, 2026.Nuclear Medicine for Alzheimer's Disease in the Hot Seat: Case Conference on Advancing Early Diagnosis With PET Imaging and Biomarkers In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/EBAC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/APF865. CME/EBAC/AAPA/IPCE credit will be available until November 21, 2026.Nuclear Medicine for Alzheimer's Disease in the Hot Seat: Case Conference on Advancing Early Diagnosis With PET Imaging and Biomarkers In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/EBAC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/APF865. CME/EBAC/AAPA/IPCE credit will be available until November 21, 2026.Nuclear Medicine for Alzheimer's Disease in the Hot Seat: Case Conference on Advancing Early Diagnosis With PET Imaging and Biomarkers In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

As new genetic and AI-powered tools emerge for bladder cancer screening, are we getting closer to reducing the need for invasive cystoscopies? In part five of the 2025 BackTable NMIBC Creator Weekend™ series, host Dr. Vignesh Packiam engages in an insightful discussion with Dr. Sarah Psutka from the University of Washington and Dr. Katie Murray from NYU about the complexities and potential benefits of using biomarkers in non-muscle invasive bladder cancer (NMIBC). --- This podcast is supported by: Ferring Pharmaceuticals https://www.ferring.com/home-classic/people-and-families/uro-uro-oncology/bladder-cancer/ --- SYNPOSIS The conversation covers the current challenges of interpreting positive biomarkers without clinical correlates, the gold standard of biopsies, and the potential of various biomarkers such as urine cytology, FISH, and newer genomic tests like the Decipher Bladder Genomic Classifier. They also touch upon the role of AI in pathology, the cost implications of biomarkers, and how these tools might influence future clinical practices and patient decisions. The episode emphasizes the need for precision medicine, careful patient counseling, and the impact of false positives and negatives on both patients and healthcare providers. --- TIMESTAMPS 00:00 - Introduction05:25 - Challenges with Current Biomarkers08:10 - New Biomarkers and Genomic Classifiers21:10 - AI and Pathology in Bladder Cancer35:13 - Screening and Future Directions41:20 - Challenges and Future Directions in Bladder Cancer Surveillance57:51 - Conclusion --- RESOURCES DaBlaCa-15 Trialhttps://pubmed.ncbi.nlm.nih.gov/40280776/ Sam Chang CHAI Studyhttps://pubmed.ncbi.nlm.nih.gov/40514253/

What if entrepreneurship could fundamentally change how we experience aging—making it more joyful, independent, and connected? On this special “ICYMI Aging” episode of The Angel Next Door Podcast, host Marcia Dawood brings together highlights from interviews with three pioneering guests who are reinventing what it means to grow older.You'll hear a recap of the insights from Dr. Kerry Burnight, who blends cutting-edge research and family wisdom to prevent elder abuse and loneliness; Hunter Ziesing, who uses tech and AI to personalize healthcare and empower people to own their wellbeing; and Bruce Simpson, an investor building the largest age tech marketplace to help seniors stay independent and financially secure.If you're curious about the future of aging, entrepreneurship, and technology's role in all of it, this episode will give you the highlights. When it comes to aging, having proactive strategies, community, and smart innovations can help us all thrive—at any age. Sign up for Marcia's newsletter to receive tips and the latest on Angel Investing!Website: www.marciadawood.comDo Good While Doing WellLearn more about the documentary Show Her the Money: www.showherthemoneymovie.comAnd don't forget to follow us wherever you are!Apple Podcasts: https://pod.link/1586445642.appleSpotify: https://pod.link/1586445642.spotifyLinkedIn: https://www.linkedin.com/company/angel-next-door-podcast/Instagram: https://www.instagram.com/theangelnextdoorpodcast/Pinterest: https://www.pinterest.com/theangelnextdoorpodcast/TikTok: https://www.tiktok.com/@marciadawood

Ruben Y Luo, Priscilla S W Yeung, Morgan W Mann, Lichao Zhang, Yifei K Yang, Andrew N Hoofnagle, Post-Translationally Modified Proteoforms as Biomarkers: From Discovery to Clinical Use, Clinical Chemistry, Volume 71, Issue 11, November 2025, Pages 1111–1124, https://doi.org/10.1093/clinchem/hvaf094

In this episode, Dr. Brendan McCarthy, Chief Medical Officer of Protea Medical Center, dives deep into estrone, one of the three key estrogens, and explains why understanding it is crucial for women's health. Learn about: The differences between estradiol, estriol, and estrone How estrone levels shift during perimenopause and menopause Why oral estrogen can dramatically increase estrone The impact of lifestyle factors like diet, body fat, stress, alcohol, and sedentary behavior on estrogen balance Practical tips to support healthy estrogen metabolism naturally Dr. McCarthy breaks down complex biochemistry in a clear, actionable way so you can take charge of your hormonal health.   Citations: 1. Bulun, Serdar E., et al. “Aromatase and Estrogen Biosynthesis in Adipose Tissue.” Endocrine Reviews, vol. 23, no. 3, 2002, pp. 305–342. 2. Labrie, Fernand, et al. “Importance of the Intracrinology of Estrogen Synthesis in Peripheral Tissues in Postmenopausal Women.” Journal of Steroid Biochemistry and Molecular Biology, vol. 118, nos. 4–5, 2010, pp. 273–279. 3. Sasano, Hironobu, and Toshihiko Harada. “Differential Expression of Aromatase and 17β-Hydroxysteroid Dehydrogenase Isoenzymes in Human Tissues.” Journal of Steroid Biochemistry and Molecular Biology, vol. 86, no. 3–5, 2003, pp. 327–333. 4. Yager, James D., and Nancy E. Davidson. “Estrogen Carcinogenesis in Breast Cancer.” New England Journal of Medicine, vol. 354, no. 3, 2006, pp. 270–282. 5. Cavalieri, Ercole L., and Eleanor G. Rogan. “Depurinating Estrogen-DNA Adducts, Mechanisms of Formation, and Prevention.” Clinical Cancer Research, vol. 16, no. 3, 2010, pp. 596–602. 6. Suba, Zsuzsanna. “Circulating Estrogens and Estrogen Metabolism in Obese Women.” Journal of Clinical Endocrinology and Metabolism, vol. 98, no. 11, 2013, pp. 4336–4344. 7. Simpson, Evan R., and Konstanze C. Pike. “Aromatase Expression in Adipose Tissue: Relationship to Obesity and Insulin Resistance.” Endocrinology, vol. 156, no. 9, 2015, pp. 3422–3435. 8. Key, Timothy J., et al. “Circulating Sex Hormones and Breast Cancer Risk Factors in Postmenopausal Women: Reanalysis of 13 Studies.” British Journal of Cancer, vol. 105, no. 5, 2011, pp. 709–722. 9. Stanczyk, Frank Z., et al. “Oral, Transdermal and Injectable Hormone Therapy: Pharmacokinetics and Effects on Estrone/Estradiol Ratios.” Menopause, vol. 24, no. 9, 2017, pp. 1080–1090. 10. Santen, Richard J., et al. “Estrogen Bioidentical Hormone Therapy: Route of Administration and Risk.” Journal of Clinical Endocrinology and Metabolism, vol. 105, no. 7, 2020, pp. 2062–2074. 11. Zeleniuch-Jacquotte, Anne, et al. “Postmenopausal Levels of Estrone, Estradiol, and Estrone Sulfate and Breast Cancer Risk.” Cancer Epidemiology, Biomarkers & Prevention, vol. 23, no. 8, 2014, pp. 1531–1539. 12. Dall, Gabriella V., and Christine L. Clarke. “Local Estrogen Biosynthesis and Signaling in Breast Cancer Progression.” Steroids, vol. 78, no. 7, 2013, pp. 639–646. 13. Heald, Anthony H., et al. “Relationships Between Serum Estrone, Insulin Resistance, and Adiposity in Postmenopausal Women.” Clinical Endocrinology, vol. 67, no. 3, 2007, pp. 340–345. 14. Kuiper, George G. J. M., et al. “Estrogen Receptor β Selectivity of Estriol and Implications for Tissue-Specific Effects.” PNAS, vol. 94, no. 17, 1997, pp. 9105–9110. 15. Michnovicz, Joseph J., et al. “Dietary Indoles and Estrogen Metabolism: Effects of Cruciferous Vegetable Intake.” Journal of Nutrition, vol. 134, no. 12, 2004, pp. 3479S–   Dr. Brendan McCarthy is the founder and Chief Medical Officer of Protea Medical Center in Arizona. With over two decades of experience, he's helped thousands of patients navigate hormonal imbalances using bioidentical HRT, nutrition, and root-cause medicine. He's also taught and mentored other physicians on integrative approaches to hormone therapy, weight loss, fertility, and more. If you're ready to take your health seriously, this podcast is a great place to start.  

Today, in association with Proteomics International, we're hearing about a new era in medicine where we can tell people not what diseases they've got, but what ones they will have in ten years' time, giving them a chance to turn things around... Like this podcast? Please help us by supporting the Naked Scientists

In this episode, Elizabeth sits down with Nate Graville, founder of Geviti, to talk about the new era of health—where prevention, biomarkers, and AI are changing the game. Nate shares how losing his father to preventable cancer inspired him to build a proactive healthcare model that helps people catch disease before it starts.He breaks down what traditional medicine gets wrong, how Big Pharma shapes medical education, and how AI and peptides are helping people take control of their health. This conversation is a wake-up call about how we approach wellness, and what's possible when we stop waiting for illness to take action.Connect with Nate Graville:Instagram: @nategravilleWebsite: www.gogeviti.com/thewellnessprocessUse code WELLNESS for 20% off your first purchase.Watch the episode on YouTube:@thewellnessprocessFollow The Wellness Process:Instagram: @thewellnessprocesspodTikTok: @thewellnessprocesspodProduced by Dear MediaSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In the second part of this two-part series, Dr. Kaitlyn Palmer explains how these biomarkers change our approach to diagnosing multiple sclerosis. Show reference: Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria. Montalban, Xavier, et al. The Lancet Neurology, Volume 24, Issue 10, 850 - 865

In part one of this two-part series, Dr. Kaitlyn Palmer discusses two new MRI biomarkers to increase diagnostic specificity for multiple sclerosis.  Show reference:  Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria. Montalban, Xavier, et al. The Lancet Neurology, Volume 24, Issue 10, 850 - 865

Send us a textIn this episode of At the Bench, Betsy Crouch and David McCulley engage in a thought-provoking conversation with Dr. Eleanor Molloy, a neonatologist and physician scientist. They explore Eleanor's journey in neonatology, the importance of inflammation in neonatal health, and the challenges and rewards of conducting research in this field. The discussion also highlights the significance of collaboration, both within research teams and with parents, to enhance clinical practice and improve outcomes for neonates. Eleanor shares insights on the role of biomarkers, the impact of sex differences in research, and the necessity of international collaboration in pediatric research. The episode concludes with reflections on the balance between clinical work and research, the importance of community in academia, and the need for a rallying call to inspire the next generation of clinician scientists.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

In this episode of the WHOOP Podcast, Founder and CEO, Will Ahmed, and Chief Product Officer, Ed Baker introduce WHOOP Advanced Labs — an all new feature that integrates 65 blood biomarkers with WHOOP data to deliver personalized coaching, clinician-reviewed reports, and actionable health insights. Learn exclusive insight about how WHOOP Advanced Labs empowers members to take control of their health, encourage lifestyle changes, and move closer to our mission at WHOOP to add 1 billion healthy years to people's lives.Sign up for WHOOP Advanced Labs(00:00) Introduction to WHOOP Advanced Labs(02:51) Biomarkers, Bloodwork, & WHOOP Data(04:03) Uploading Past Bloodwork: How It Works(07:54) WHOOP Advanced Labs Subscription with Quest Diagnostics(12:03) Analyzing the 65 Key Biomarkers with WHOOP(13:34) Healthspan: Applying Advanced Labs Data to Weekly Habits(14:36) Bloodwork and Biomarkers as a Baseline For Sleep, Recovery, and Health(15:43) Data Made Simple(17:13) The Bigger Picture: The Future of WHOOP Advanced Labs(18:45) Privacy Assurance & Protecting User Data(19:30) Impact of Advanced Labs on Daily HabitsThe first 100 members to tap this link will unlock early access to WHOOP Advanced Labs.**Open the link on the same device as your WHOOP app.Support the showFollow WHOOP: www.whoop.com Trial WHOOP for Free Sign up for WHOOP Advanced Labs Instagram TikTok YouTube X Facebook LinkedIn Follow Will Ahmed: Instagram X LinkedIn Follow Kristen Holmes: Instagram LinkedIn Follow Emily Capodilupo: LinkedIn

My guest is Michael Snyder, PhD, professor of genetics at Stanford and an expert in understanding why people respond differently to various foods, supplements, behavioral and prescription interventions. We discuss how to optimize your health and lifespan according to what type of glucose responder you are, which genes you express, your lifestyle and other factors. Dr. Snyder also explains the key ages when you need to be particularly mindful about following certain health practices. We also discuss how people respond in opposite ways to different fiber types. This episode ought to be of interest and use to anyone seeking to understand their unique biological needs and how to go about meeting those needs. Sponsors AGZ by AG1: https://drinkag1.com/huberman Wealthfront*: https://wealthfront.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman *This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Timestamps 00:00 Michael Snyder 03:33 Healthy Glucose Range, Continuous Glucose Monitors CGM, Hemoglobin A1c 09:02 Individual Variability & Food Choice, Glucose Spikes & Sleepiness 12:18 Sponsors: AGZ by AG1 & Wealthfront 15:16 Glucose Spikes, Tools: Post-Meal Brisk Walk; Soleus “Push-Ups”; Exercise Snacks 21:06 Glucose Dysregulation, Diabetes & Sub-Phenotypes, Tool: Larger Morning Meal 28:34 Exercise Timing, Muscle Insulin Resistance 30:49 Diabetes Subtyping, Weight, Glucose Control; Incretins 35:41 GLP-1 Agonists, Diabetes, Tool: Muscle Maintenance & Resistance Training 38:40 Metformin, Berberine, Headaches 41:01 GLP-1 Agonists, Cognition, Longevity, Tool: Habits Support Medication; Cycling 47:41 Subcutaneous vs Visceral Fat, Organ Stress 49:10 Sponsors: David & Eight Sleep 51:58 Meal Timing & Sleep, Tools: Post-Dinner Walk, Routines, Bedtime Consistency 57:16 Microbiome, Immune System & Gut; Diet & Individual Variability 1:02:52 Fiber Types, Cholesterol & Glucose, Polyphenols 1:09:50 Food As Medicine; Fiber, Microbiome & Individual Variability; Probiotics 1:18:48 Sponsor: Function 1:20:35 Profiling Healthy Individuals, Genomes, Wearables 1:26:31 Whole-Body MRIs, Nodules, Healthy Baseline, Early Diagnosis 1:34:07 Sensors, CGM, Sleep, Heart Rate Variability HRV, Tools: Mindset Effects, Increase REM 1:39:30 HRV, Sleep, Exercise, Tool: Long Exhales; Next-Day Excitement & Sleep 1:42:48 Organ Aging, “Ageotypes”; Biological Age vs Chronological Age 1:49:41 Longevity, Health Span, Genetics, Blue Zones 1:52:19 Epigenetics, Viral Infection & Disease 1:58:54 ALS, Heritability; Neuroprotection, Nicotine 2:03:47 Air Quality, Allergies, DEET & Pesticides, Inflammation, Mold; Microplastics 2:15:02 Single-Drop Blood Test & Biomarkers, Wearables, Observational Trials 2:20:33 Acupuncture, Blood Pressure 2:26:40 Immersive Events & Mental Health Benefits 2:34:59 Data, Nutrition & Lifestyle; Siloed Health Care vs Personalized Medicine 2:43:06 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Social Media, Neural Network Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices