Podcasts about biomarkers

"Our goal of precision oncology has been to shift to tailored therapies that can help to improve treatment efficacy and ultimately improve patient outcomes. Resistance biomarker testing can help the care team to detect these genomic changes that the tumor may have acquired during therapy that makes the cells resistant to therapy. This information can be extremely helpful when we're talking about making choices about second-line or subsequent-line therapy," ONS member Danielle Fournier, DNP, APRN, AGPCNP-BC, AOCNP®, advanced practice RN at the University of Texas MD Anderson Cancer Center in Houston, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about drug resistance biomarker testing. This podcast episode is sponsored by AstraZeneca. ONS is solely responsible for the criteria, objectives, content, quality, and scientific integrity of its programs and publications. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Episode Notes  This episode is not eligible for NCPD credit.  ONS Podcast™ episodes: Episode 389: Biomarker Testing for Non-Small Cell Lung Cancer Episode 373: Biomarker Testing in Prostate Cancer Episode 169: How Biomarker Testing Drives the Use of Targeted Therapies ONS Voice articles: Help Your Patients Understand Biomarker Resistance Testing Key Patient Education Points for Biomarker Resistance Testing Quick Quiz: How Much Do You Know About Drug Resistance in Cancer? Quick Quiz: How Much Do You Know About Somatic Biomarker Resistance Testing? When Targeted Therapy Stops Working, What's Next? Discover How Biomarker Resistance Testing Opens New Doors ONS Biomarker Database Clinical Journal of Oncology Nursing article: Tumor-Agnostic Therapies Reshaping Cancer Care ONS book: Understanding Genomic and Hereditary Cancer Risk: A Handbook for Oncology Nurses ONS course: Genomic Foundations for Precision Oncology ONS Genomics and Precision Oncology Learning Library American Cancer Society Cancer Action Network: Access to Biomarker Testing page White paper: The Landscape of Biomarker Testing Coverage in the United States Find out which states are currently discussing biomarker testing bills and how you can advocate for them through ONS. To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "We know that biomarkers are playing an ever more important role in cancer care, and really, their use can range anywhere from helping us to confirm a given diagnosis, understand a patient's cancer susceptibility or risk, evaluate prognosis, as well as personalize treatment recommendations. … But in some cases, though, biomarkers can also help us to avoid therapies that are not likely to work. We also call these drug resistance biomarkers. These are those biomarkers that signify that a tumor is unlikely to respond to a given therapy." TS 1:50 "Resistance to cancer therapies is one of the most common issues that arises during cancer treatment. Because the populations of cancer cells within a tumor can be very diverse, when a given drug kills the cells that are sensitive to that therapy, it can also eventually leave behind resistant tumor cells, which can grow and multiply over time. So this can ultimately lead to a point where the treatment that was initially effective is no longer able to control the disease." TS 4:33 "While costs have come down, there can still be a cost associated with biomarker testing, and in some cases, this can be considered a barrier to care. What patients pay out of pocket can vary widely depending on their insurance coverage. So we have some data that was published from the American Cancer Society Cancer Action Network, and this was published a few years ago in 2023, which showed the average allowed unit cost to insurers per biomarker test ranged anywhere from about $79 for patients who were on Medicaid to about $224 for large-group, self-insured patients." TS 10:03 "There's research underway that's looking not only at genomic changes—so DNA changes that impact drug resistance—but how other substances such as RNA and proteins within the cell can also contribute to drug resistance. And this kind of falls into not just genomics but multiomics field. I have no doubt whatsoever that the use of artificial intelligence and machine learning is likely going to play a large role in drug resistance research. And really, these tools can help researchers to analyze complex data sets, identify novel resistance biomarkers, predict resistance patterns, as well as help to develop treatments that may overcome some of those resistance mechanisms." TS 17:00

It's an era of breakthroughs in Alzheimer's research, yet for many clinicians, it's also a time of profound uncertainty. We are currently navigating competing definitions of the disease, multiple new biomarkers coming on market seemingly every week, and the clinical rollout of new amyloid antibodies. How do we translate this rapid-fire science into daily practice? On this week's GeriPal podcast, we sit down with dementia experts Halima Amjad, Barak Gaster, and Heather Whitson. We dive deep into: The evolving definitions of Alzheimer's disease.  Does someone have Alzheimer's disease if you have only an abnormal biomarker as defined by the Alzheimer's Association, or is amyloid pathology necessary but not sufficient to define Alzheimer's as per the International Working Group (IWG) recommendations? Where do blood-based biomarkers for Alzheimer's fit into the diagnostic workup, and should they be used at all in primary care?  FYI - here is my take on that question in a recent JAMA IM article titled "The Limited Role of Alzheimer's Disease Blood-Based Biomarkers in Primary Care." What's the role of amyloid antibodies in the care of individuals with Alzheimer's disease, including who to use them on? We covered a lot and discussed some of these resources that you can do a deeper dive on: Blood-based biomarker resources JAMA article on Blood-Based Biomarkers for Alzheimer's Disease: Preventing Unintended Consequences  Alzheimer's Dementia article on Blood-based biomarkers for detecting Alzheimer's disease pathology in cognitively impaired individuals within specialized care settings: A systematic review and meta-analysis JAMA IM article on The Limited Role of Alzheimer Disease Blood-Based Biomarkers in Primary Care Appropriate use recommendations for amyloid antibodies Donanemab: Appropriate use recommendations  Lecanemab: Appropriate Use Recommendations Primary Care Resources Cognition in Primary Care program A JAGS article on "Large Health System Quality Improvement Intervention Providing Training and Tools to Improve Detection of Cognitive Impairment in Primary Care" Other resources AGS's new online curriculum for Alzheimer's Disease By Eric Widera  

Biomechanist Katy Bowman and biologist Dr. Jeannette Loram explain how just nine minutes of vigorous activity can make a measurable difference for your cardiovascular health. They break down what counts as vigorous exercise, how to gauge it “old skool” without complicated gadgets, and how much is needed based on the movement patterns of the heart-healthy Hadza. Plus, they share nine practical ways to fit short bursts of higher-intensity movement into your day, from running stairs and kitchen dance parties to treading water in a pool.The episode also explores a personal experience related to the menopause transition, including the onset of salt sensitivity, water retention, and hypertension. Katy and Jeannette discuss the link between estrogen and salt management, explaining why the loss of estrogen can make women more susceptible to salt-induced high blood pressure—and what lifestyle shifts can help protect heart health.Enhanced Show Notes and Full Transcript00:00 — Introduction & Sponsors01:50 — Heart Health and Midlife Movement03:45 — What Counts as Vigorous Exercise?07:00 — How Much Vigorous Do We Actually Need? Insights from the Hadza 12:30 — Nine Minutes of Vigorous Movement: Practical Ideas to fit into your life25:00 — Listener Question: Vigorous Movement in the Pool36:20 — Warming Up for Vigorous Movement Snacks 41:30 — Salt Sensitivity, Menopause & Blood PressureLinks & Research Mentioned:Physical Activity Patterns and Biomarkers of Cardiovascular Disease Risk in Hunter Gatherers  by Raichlen et al (2017) Lifestyle and Patterns of Physical Activity in Hadza Foragers by Sayre et al (2023)Association of wearable device-measured vigorous intermittent lifestyle physical activity with mortality by Stamatakis et al (2022) Postmenopausal Salt Sensitivity and Hypertension by Kim et al (2014)Estrogen negatively regulates the renal epithelial sodium channel (ENaC) by promoting Derlin-1 expression and AMPK activation by Zhang et al (2019) Salt Sensitivity of Blood Pressure in Women by Barris et al (2023)Connect, Move & Learn:Join Our Newsletter: Movement Colored GlassesFollow Katy on SubstackTry Katy's Virtual Studio Free for 7 days!Made Possible By Our Wonderful Sponsors:Movemate: Active standing boards with smoothly articulating wooden slats. Designed to keep you moving without interrupting your focus.Peluva: Five-toe minimalist shoes that move like you do—take 10% off with code NUTRITIOUSMOVEMENTMy Happy Feet: Toe-spacing socks that gently realign toes for comfortable recovery—take 20% off with code MYDNA.Venn Design: Beautifully upholstered ball-shaped Air Chairs that encourage dynamic sitting.Ikaria Design: The Soul Seat® offers height-adjustable, multi-position sitting—get 10% off new chairs and desks with code DNA10.Smart Playrooms: Beautiful playroom design and movement-rich equipment—save 10% on monkey bars and rock-wall items with code DNA10.Thoughts/questions email us at podcast@nutritiousmovement.comYour Voice on the Podcast: Read The Credits 

As technology continues to reshape the health and wellness landscape, innovators like Jason Moore are leading the charge toward smarter, more personalized health insights. In todays episode, we sit down with Jason Moore, CEO and founder of Spren, to explore a groundbreaking platform that leverages smartphone-based technology to measure body composition, heart rate variability (HRV), and metabolic signals—while delivering personalized nutrition guidance and continuous AI-driven coaching. With more than a decade dedicated to studying digital biomarkers, Jason has focused on making advanced physiological data accessible to everyday people. Driven by curiosity and a passion for scientific discovery, he works alongside leading researchers to transform complex health data into actionable insights that empower individuals to optimize their performance and well-being. In this conversation, we explore: ·       What digital biomarkers are and how they're revolutionizing health monitoring. ·       Why HRV is one of the most powerful indicators of stress, recovery, and overall resilience. ·       How smartphone-based technology can accurately analyze body composition and metabolic health. To learn more from Jason, connect with him on Instagram and LinkedIn. Episode also available on Apple Podcasts: https://apple.co/38oMlMr 

Today, I'm joined by the extraordinary Dr. Natalie Yivgi-Ohana, a pioneering scientist whose passion for mitochondria unlocks new frontiers in longevity medicine. Our conversation truly blew my mind—Dr. Yivgi-Ohana brings decades of expertise to demystify these tiny, ancient powerhouses that fuel every cell in our bodies, impact our hormones, drive immunity, and, as it turns out, play a central role in how we age.   Episode Timestamps: Welcome to the Longevity Podcast and today's focus on mitochondria ... 00:00:00 Maternal inheritance and critical functions of mitochondria ... 00:05:56 Mitochondria as energy producers and hormone regulators ... 00:07:03 Aha moments: mitochondria control life, death, and disease ... 00:08:55 Endosymbiotic theory: how mitochondria originated ... 00:10:19 Chronic disease, aging, and the connection to mitochondria ... 00:16:10 Substrate fuels: carbs, fats, and importance of metabolic flexibility ... 00:20:18 Mitochondria's control over immune system and signaling ... 00:26:39 Mitochondrial transfer: how cells share organelle "powerhouses" ... 00:32:42 Groundbreaking therapy: transplanting mitochondria for rare diseases ... 00:36:40 Expanding mitochondrial therapies to age-related diseases ... 00:42:57 Aging in women: hormones, mitochondria, and inflection points ... 00:51:00 Stem cell exhaustion and cellular renewal ... 00:52:24 Biomarkers: ways to measure mitochondrial health ... 01:03:11 Supplements, lifestyle, and emotional health for mitochondria ... 01:15:47 Medication choices and minimizing mitochondrial toxicity ... 01:24:04   Our Amazing Sponsors: O₃RACLE by Wizard Sciences — A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off.   Magnesium Breakthrough by BIOptimizers — A full-spectrum magnesium supplement combining seven highly absorbable forms to support sleep, stress, muscle recovery, and nervous system balance in one nightly habit. Save 15% at bioptimizers.com/bionat with code BIONAT   Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Dr. Bill Lawrence Episode

The Most Powerful Drug Ever? The GLP-3 Revolution ExplainedWhat if the most powerful drug ever created is already here, and we're not fully prepared to use it correctly?In this episode of the Smart Nutrition Made Simple Show, Ben Brown sits down with Jay Campbell, five-time international best-selling author and leading expert in hormonal optimization, performance enhancement, and longevity science, to unpack the GLP-3 revolution.Jay explains why Retatrutide, the newest GLP drug in development, is already being forecasted as “the greatest drug of all time” — and how it may fundamentally redefine fat loss, metabolic health, and longevity.But this conversation goes deeper than hype.We explore the biomedical revolution unfolding right now, how GLP-1, GLP-2, and GLP-3 drugs actually work, why most people are using them incorrectly, and the difference between strategic microdosing and reckless overdosing.Jay breaks down:• Why Retatrutide could potentially end obesity• Why dosing strategy changes everything• How GLP drugs influence appetite, inflammation, brain signaling, and metabolic pathways• Why foundation matters more than pharmaceuticals• The psychological and physiological implications of long-term use• What the next decade of metabolic medicine may look likeThis is not a surface-level fat loss discussion. It's a conversation about discernment, responsibility, and how to use powerful tools without becoming dependent on them.If GLP-3 truly represents a biomedical revolution, the real question becomes: Are we ready for it?Tune in now to understand the science behind GLP-3, Retatrutide, metabolic optimization, and the future of human performance.Timestamps00:00 – Retatrutide Is GLP-301:12 – “The Greatest Drug of All Time?”03:40 – GLP-1 vs GLP-2 vs GLP-3 Explained07:15 – Appetite Suppression vs Metabolic Rewiring12:20 – The Dosing Problem in Clinical Medicine18:30 – Microdosing vs High Clinical Doses22:45 – Can Retatrutide End Obesity?26:00 – Why Foundation Still Wins: Sleep, Protein, Resistance Training30:10 – Brain Chemistry, Addiction, and GLP Effects34:20 – Biomarkers, Inflammation & Metabolic Health39:50 – Rebound Weight Gain and Microdose Strategy44:30 – The Biomedical Revolution47:10 – Overreach vs Optimization52:00 – Where to Connect with JayConnect with Jay CampbellWebsite: https://jaycampbell.comInstagram: https://www.instagram.com/jaycampbell333Links & ResourcesConnect with Ben on Instagram: https://www.instagram.com/bodysystemscoaching/Learn more about Ben's coaching program: www.bodysystems.comSubscribe to the Smart Nutrition Made Simple Show on Apple Podcasts - https://podcasts.apple.com/us/podcast/the-smart-nutrition-made-simple-show-with-ben-brown/id1244912234Spotify - https://open.spotify.com/show/4H8vUlwYvKcAXZOv84sFgTYoutube - https://www.youtube.com/@bodysystemscoachingBook Free Nutrition Strategy Call - https://bodysystems.com/free-strategy-call/

In this episode of The Dr. Ashley Show, I sit down with Dr. Traci Gapin to break down performance medicine, HRV tracking, testosterone optimization for men and women, gut health, creatine supplementation, and the real root causes behind low energy and metabolic dysfunction. We dive deep into biomarkers, protein intake, sleep optimization, CGMs, and how to take control of your metabolic health instead of relying on the broken traditional healthcare model. I just released another video that walks you through exactly how to lose weight rapidly without wrecking your hormones or crashing your energy.Watch it here: ⁠⁠https://youtu.be/IRLOzby5FBQ⁠⁠ GET A CUSTOMIZED WEIGHT LOSS PLAN: Have a free 1-on-1 call with our Expert Nutritionists

Christine Trimpe was morbidly obese, pre-diabetic, and couldn't walk a half-mile mountain trail. Ten years later, she's lost over 100 pounds, reversed fatty liver disease and sleep apnea, and coaches thousands of women through metabolic healing - all by quitting sugar.In this episode, Christine shares her turning point moment on a Rocky Mountain trail, how discovering Dr. Jason Fung's work changed everything, why "everything in moderation" is the most dangerous dietary advice, and the surprising role that joy plays in metabolic recovery.We also discuss:- How sugar is a major hormone disruptor and the root cause of fatty liver disease- Why sugar addiction has physical, emotional, and spiritual dimensions- The circadian rhythm hacks (morning sunlight, blue light blockers, early eating windows) that transformed her sleep- Why keto gets a bad rap and what it actually looks like in practice- The "everything in moderation" myth and why it leads to relapse- Her take on GLP-1 agonists (Ozempic) for weight loss- Real coaching success stories: 100+ pound weight loss, 5K runs, and life transformations- What she'd do differently if she could restart her journey today- Why midlife metabolism isn't doomed - she reached her healthy weight right before her 50th birthdayWebsite: ChristineTrimpe.comBook: "Sugar Freed: Stop Losing the Weight Loss Battle, Start Gaining the Victory" - Available on Amazon, Barnes and Noble, independent bookstores, and your public libraryFree Chapter: Available at ChristineTrimpe.com (top of homepage)Mentioned in this episode:- Dr. Jason Fung - "The Hunger Code" (new book)Host: Dr. Robert LufkinSubscribe for new episodes every Tuesday.#MetabolicHealth #SugarAddiction #WeightLoss #Keto #JasonFung #SugarFreed #ChristineTrimpe #Longevity #HealthLongevitySecretsContinue this conversation on SubStack: https://robertlufkinmd.substack.com Get 120 Biomarkers for $99 and CT Calcium scans anywhere in the US. https://www.vitalsvault.com/ Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/ Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmd Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Bluesky: ...

Today I sit down with Dr. Tawni Tidwell, a biocultural anthropologist and Tibetan medicine doctor at the Center for Healthy Minds at the University of Wisconsin–Madison. Together we discuss how Tibetan medicine approaches the challenges that arise in the course of meditation. Along the way, we talk about reconnecting with indigenous knowledge, establishing a more intimate relationship with the body and the land, and the importance of social context in supporting spiritual practice. If you want to hear scholars and practitioners engaging in deep conversations about the dark side of Asian religions and medicines, then subscribe to Black Beryl wherever you get your podcasts. Also check out our members-only benefits on Substack.com to see what our guests have shared with you. Enjoy the show! Resources related to this conversation: Tawni Tidwell, “Life in Suspension with Death: Biocultural Ontologies, Perceptual Cues, and Biomarkers for Tibetan Tukdam Postmortem Meditative State” (2024) Tawni Tidwell et al, “Effect of Tibetan Herbal Formulas on Symptom Duration Among Ambulatory Patients with Native SARS-CoV-2 Infection: A Retrospective Cohort Study” (2024) Tawni Tidwell, “Tibetan Medical Paradigms for the SARS-CoV-2 Pandemic: Understanding COVID-19, Microbiome Links, and Its Sowa Rigpa Nosology” (2021) New open access book! Crafting Potency: Sowa Rigpa Artisanship Across the Himalayas Tawni's research profile at the Center for Healthy Minds Please note that Tawni is not taking new patients at this time, but she recommends the American Tibetan Medical Association Become a paid subscriber on blackberyl.substack.com to unlock our members-only benefits, including downloading scholarly articles by Dr Tidwell Pierce Salguero is a transdisciplinary scholar of health humanities who is fascinated by historical and contemporary intersections between Buddhism, medicine, and crosscultural exchange. He has a Ph.D. in History of Medicine from the Johns Hopkins School of Medicine and teaches Asian history, medicine, and religion at Penn State University's Abington College, located near Philadelphia. See www.piercesalguero.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

Today I sit down with Dr. Tawni Tidwell, a biocultural anthropologist and Tibetan medicine doctor at the Center for Healthy Minds at the University of Wisconsin–Madison. Together we discuss how Tibetan medicine approaches the challenges that arise in the course of meditation. Along the way, we talk about reconnecting with indigenous knowledge, establishing a more intimate relationship with the body and the land, and the importance of social context in supporting spiritual practice. If you want to hear scholars and practitioners engaging in deep conversations about the dark side of Asian religions and medicines, then subscribe to Black Beryl wherever you get your podcasts. Also check out our members-only benefits on Substack.com to see what our guests have shared with you. Enjoy the show! Resources related to this conversation: Tawni Tidwell, “Life in Suspension with Death: Biocultural Ontologies, Perceptual Cues, and Biomarkers for Tibetan Tukdam Postmortem Meditative State” (2024) Tawni Tidwell et al, “Effect of Tibetan Herbal Formulas on Symptom Duration Among Ambulatory Patients with Native SARS-CoV-2 Infection: A Retrospective Cohort Study” (2024) Tawni Tidwell, “Tibetan Medical Paradigms for the SARS-CoV-2 Pandemic: Understanding COVID-19, Microbiome Links, and Its Sowa Rigpa Nosology” (2021) New open access book! Crafting Potency: Sowa Rigpa Artisanship Across the Himalayas Tawni's research profile at the Center for Healthy Minds Please note that Tawni is not taking new patients at this time, but she recommends the American Tibetan Medical Association Become a paid subscriber on blackberyl.substack.com to unlock our members-only benefits, including downloading scholarly articles by Dr Tidwell Pierce Salguero is a transdisciplinary scholar of health humanities who is fascinated by historical and contemporary intersections between Buddhism, medicine, and crosscultural exchange. He has a Ph.D. in History of Medicine from the Johns Hopkins School of Medicine and teaches Asian history, medicine, and religion at Penn State University's Abington College, located near Philadelphia. See www.piercesalguero.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/buddhist-studies

Today I sit down with Dr. Tawni Tidwell, a biocultural anthropologist and Tibetan medicine doctor at the Center for Healthy Minds at the University of Wisconsin–Madison. Together we discuss how Tibetan medicine approaches the challenges that arise in the course of meditation. Along the way, we talk about reconnecting with indigenous knowledge, establishing a more intimate relationship with the body and the land, and the importance of social context in supporting spiritual practice. If you want to hear scholars and practitioners engaging in deep conversations about the dark side of Asian religions and medicines, then subscribe to Black Beryl wherever you get your podcasts. Also check out our members-only benefits on Substack.com to see what our guests have shared with you. Enjoy the show! Resources related to this conversation: Tawni Tidwell, “Life in Suspension with Death: Biocultural Ontologies, Perceptual Cues, and Biomarkers for Tibetan Tukdam Postmortem Meditative State” (2024) Tawni Tidwell et al, “Effect of Tibetan Herbal Formulas on Symptom Duration Among Ambulatory Patients with Native SARS-CoV-2 Infection: A Retrospective Cohort Study” (2024) Tawni Tidwell, “Tibetan Medical Paradigms for the SARS-CoV-2 Pandemic: Understanding COVID-19, Microbiome Links, and Its Sowa Rigpa Nosology” (2021) New open access book! Crafting Potency: Sowa Rigpa Artisanship Across the Himalayas Tawni's research profile at the Center for Healthy Minds Please note that Tawni is not taking new patients at this time, but she recommends the American Tibetan Medical Association Become a paid subscriber on blackberyl.substack.com to unlock our members-only benefits, including downloading scholarly articles by Dr Tidwell Pierce Salguero is a transdisciplinary scholar of health humanities who is fascinated by historical and contemporary intersections between Buddhism, medicine, and crosscultural exchange. He has a Ph.D. in History of Medicine from the Johns Hopkins School of Medicine and teaches Asian history, medicine, and religion at Penn State University's Abington College, located near Philadelphia. See www.piercesalguero.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/psychology

Today I sit down with Dr. Tawni Tidwell, a biocultural anthropologist and Tibetan medicine doctor at the Center for Healthy Minds at the University of Wisconsin–Madison. Together we discuss how Tibetan medicine approaches the challenges that arise in the course of meditation. Along the way, we talk about reconnecting with indigenous knowledge, establishing a more intimate relationship with the body and the land, and the importance of social context in supporting spiritual practice. If you want to hear scholars and practitioners engaging in deep conversations about the dark side of Asian religions and medicines, then subscribe to Black Beryl wherever you get your podcasts. Also check out our members-only benefits on Substack.com to see what our guests have shared with you. Enjoy the show! Resources related to this conversation: Tawni Tidwell, “Life in Suspension with Death: Biocultural Ontologies, Perceptual Cues, and Biomarkers for Tibetan Tukdam Postmortem Meditative State” (2024) Tawni Tidwell et al, “Effect of Tibetan Herbal Formulas on Symptom Duration Among Ambulatory Patients with Native SARS-CoV-2 Infection: A Retrospective Cohort Study” (2024) Tawni Tidwell, “Tibetan Medical Paradigms for the SARS-CoV-2 Pandemic: Understanding COVID-19, Microbiome Links, and Its Sowa Rigpa Nosology” (2021) New open access book! Crafting Potency: Sowa Rigpa Artisanship Across the Himalayas Tawni's research profile at the Center for Healthy Minds Please note that Tawni is not taking new patients at this time, but she recommends the American Tibetan Medical Association Become a paid subscriber on blackberyl.substack.com to unlock our members-only benefits, including downloading scholarly articles by Dr Tidwell Pierce Salguero is a transdisciplinary scholar of health humanities who is fascinated by historical and contemporary intersections between Buddhism, medicine, and crosscultural exchange. He has a Ph.D. in History of Medicine from the Johns Hopkins School of Medicine and teaches Asian history, medicine, and religion at Penn State University's Abington College, located near Philadelphia. See www.piercesalguero.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/religion

Today I sit down with Dr. Tawni Tidwell, a biocultural anthropologist and Tibetan medicine doctor at the Center for Healthy Minds at the University of Wisconsin–Madison. Together we discuss how Tibetan medicine approaches the challenges that arise in the course of meditation. Along the way, we talk about reconnecting with indigenous knowledge, establishing a more intimate relationship with the body and the land, and the importance of social context in supporting spiritual practice. If you want to hear scholars and practitioners engaging in deep conversations about the dark side of Asian religions and medicines, then subscribe to Black Beryl wherever you get your podcasts. Also check out our members-only benefits on Substack.com to see what our guests have shared with you. Enjoy the show! Resources related to this conversation: Tawni Tidwell, “Life in Suspension with Death: Biocultural Ontologies, Perceptual Cues, and Biomarkers for Tibetan Tukdam Postmortem Meditative State” (2024) Tawni Tidwell et al, “Effect of Tibetan Herbal Formulas on Symptom Duration Among Ambulatory Patients with Native SARS-CoV-2 Infection: A Retrospective Cohort Study” (2024) Tawni Tidwell, “Tibetan Medical Paradigms for the SARS-CoV-2 Pandemic: Understanding COVID-19, Microbiome Links, and Its Sowa Rigpa Nosology” (2021) New open access book! Crafting Potency: Sowa Rigpa Artisanship Across the Himalayas Tawni's research profile at the Center for Healthy Minds Please note that Tawni is not taking new patients at this time, but she recommends the American Tibetan Medical Association Become a paid subscriber on blackberyl.substack.com to unlock our members-only benefits, including downloading scholarly articles by Dr Tidwell Pierce Salguero is a transdisciplinary scholar of health humanities who is fascinated by historical and contemporary intersections between Buddhism, medicine, and crosscultural exchange. He has a Ph.D. in History of Medicine from the Johns Hopkins School of Medicine and teaches Asian history, medicine, and religion at Penn State University's Abington College, located near Philadelphia. See www.piercesalguero.com. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/spiritual-practice-and-mindfulness

The JournalFeed podcast for the week of March 2-6, 2026.These are summaries from just 2 of the 5 articles we cover every week! For access to more, please visit JournalFeed.org for details about becoming a member.Wednesday's Spoon Feed:Combined elevation in two blood biomarkers (GFAP and UCH-L1) showed high sensitivity and negative predictive value (NPV) for positive findings on head CT in anticoagulated patients with mild traumatic brain injury but were not helpful at identifying who would develop post-concussive syndrome.Thursday's Spoon Feed:In this randomized controlled trial, adding 1 liter of IV normal saline to intramuscular diclofenac for acute migraine in the ED did not significantly improve pain relief at 2 hours compared with diclofenac alone.

Today, I'm joined by the insightful Courtney Van Bussum, a biomedical engineer and entrepreneur who has become a rising force in longevity science. Courtney shares how growing up in a family of healthcare innovators shaped her journey, and how she pivoted from startup life to tackling age-related challenges—especially when COVID brought her back to her roots and reignited her passion for cellular health. If you want to try Endotelio 1-MNA and save 10% click here and code NAT10 will be entered for you at checkout.    Episode Timestamps: Welcome and introduction to Longevity Podcast ... 00:00:00 Challenging beliefs about aging and cellular health ... 00:12:00 Deep dive into NAD+ biochemistry and cellular function ... 00:13:08 NAD+/NADH balance: Why both matter ... 00:15:24 Why NAD+ declines: Not just aging, but increased degradation ...00:18:26 The role of CD38 and NMNT enzymes in NAD metabolism ... 00:20:14 Controversy and confusion: NAD+ precursors (NR, NMN) and IVs ... 00:22:28 Methylation's hidden importance in NAD supplementation ... 00:30:55 Supplementing 1-MNA: Understanding dosages and applications ... 00:50:54 Assessing NAD+ status: Biomarkers and limitations of testing ... 00:53:01 Lifestyle ROI: Sleep, exercise, and circadian rhythm for NAD preservation ... 00:57:14 Ketones: Beyond performance, supporting cellular energy and longevity ... 01:06:03 Future of NAD science: Anticipating new insights and risks ... 01:11:45 Confidence and humility: Advice for navigating the longevity field ... 01:18:52   Our Amazing Sponsors: Qualia Creatine+ by Qualia Life – A clinically formulated blend of two highly bioavailable forms of creatine plus magnesium and electrolytes to support lean muscle, cellular energy, and brain health—especially for women over 40 who naturally produce less with age. Go to qualialife.com/nathalie and use code NATHALIE to save up to 50%, plus an additional 15% off.   Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset after the holidays without suffering. Go  to lvluphealth.com and use code NAT for 20% off. Gut Essentials Bundle by Just Thrive Health – This powerhouse duo pairs the only probiotic clinically proven to arrive 100% alive in your gut with science-backed Digestive Bitters to reduce bloat, curb cravings, and support better energy fast. Take the Just Thrive Feel Better Challenge and save 20% at justthrivehealth.com/NAT20 with code NAT20.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Dr. Bill Lawrence Episode

Biomarkers of aging help researchers understand how diseases influence the body over time. However, most current biomarkers rely on measurements from mixed cell populations, making it difficult to distinguish between changes caused by shifts in cell types and aging processes occurring within individual cells. In this study, titled “Single-cell transcriptomics reveal intrinsic and systemic T cell aging in COVID-19 and HIV” and published in Volume 18 of Aging-US, researchers used single-cell RNA sequencing to analyze aging-related changes in human T cells. They developed Tictock, a single-cell transcriptomic clock that predicts both cellular age and T cell type across six human T cell subsets. Applying this tool, the researchers found that acute COVID-19 was associated with increased proportions of CD8⁺ cytotoxic T cells, while T cell composition remained relatively stable in individuals with HIV receiving antiretroviral therapy (HIV+ART). Despite these differences, both conditions showed signs of accelerated transcriptomic aging, particularly in naïve CD8⁺ T cells. Further analysis identified shared aging-related genes and biological pathways linked to ribosomal components and TNF receptor binding. These findings demonstrate how single-cell transcriptomic biomarkers can help separate systemic immune changes from cell-intrinsic aging processes, providing new tools to measure immune aging in disease. DOI - https://doi.org/10.18632/aging.206353 Corresponding author - Eric Verdin - EVerdin@buckinstitute.org Abstract video - https://www.youtube.com/watch?v=_r3AF7OrgKY Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206353 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, transcriptomic clock, aging biomarkers, systemic aging, intrinsic aging To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

What if perimenopause could actually become one of the strongest, healthiest seasons of your life? In this episode, Louise, one of the world's leading women's integrative health practitioners, performance scientists, and exercise physiologists, sits down with Jen to share a transformation story that challenges everything many women believe about aging, hormones, body recomposition, running, and performance!Jen highlights how simple, consistent strategies like whole-food nutrition, strategic strength training, and fueling that works with our unique changing hormones and female physiology can lead to meaningful changes in body composition, energy, confidence, and biomarkers without relying heavily on medications or extreme protocols. The conversation explores how small, sustainable, and highly strategic habits compound over time, why a community of strong women's support matters most during midlife, and mindset shifts that can help women move from feeling stuck to feeling empowered.Listeners will walk away with reassurance that progress does not require perfection, endless supplements, diets, or expensive tools. Instead, it comes from learning how to work with our female body, not against it. Whether you are navigating hormonal changes, struggling with a fitness plateau, or want to feel your best in your body, this episode offers hope, clarity, and practical perspective.RESOURCES + LINKSFind the Injury Prevention for Women Runners 30+ and a Female Runners Guide to Support Optimal Ferritin courses mentioned here.Grab our free monthly goal planning calendar & learn how to use it here.Get $25 off Function Health labs here or use code LVALENTINE11Find FullScript here and see curated supplement picks. Save 20% off the Red Yeast Rice & ALA mentioned in this episode. A small portion of the sale goes back to support BTW. Thank you!Learn with my free nutrition guide and award-winning Academy to thrive through perimenopause with less stress: https://www.breakingthroughwellness.com/ Save 20% off Kion's science-backed clean products. Code "LOUISE" saves on all future orders: : https://www.getkion.com/pages/maximizingEpisode Highlights:(2:55) Jen's success and community impact(5:39) Home workouts and building confidence(8:02) Why many women feel stuck in fitness(10:40) Staying consistent during vacation(11:33) Nutrition timing and lifestyle flexibility(14:55) Retreats and community support(17:55) Motivation through shared goals(20:30) Coaching structure and accountability(24:57) Improving biomarkers without medication(29:30) Science-based strategy and synergy approach(34:48) Changing the narrative around perimenopause(38:36) Balancing performance with long-term health(40:33) Tracking cycles, nutrition, and progress(45:24) Advice for women feeling stuck(48:41) OutroTune in weekly to "Maximizing Hormones, Physique, and Running Through Perimenopause" for our simple female-specific science-based revolution. Let's unlock our best with less stress!I'd love to connect! Email

Today I sit down with Dr. Tawni Tidwell, a biocultural anthropologist and Tibetan medicine doctor at the Center for Healthy Minds at the University of Wisconsin–Madison. Together we discuss how Tibetan medicine approaches the challenges that arise in the course of meditation. Along the way, we talk about reconnecting with indigenous knowledge, establishing a more intimate relationship with the body and the land, and the importance of social context in supporting spiritual practice.If you want to hear scholars and practitioners engaging in deep conversations about the dark side of Asian religions and medicines, then subscribe to Black Beryl wherever you get your podcasts. Also check out our members-only benefits on Substack.com to see what our guests have shared with you. Enjoy the show!Resources related to this conversation:Tawni Tidwell, “Life in Suspension with Death: Biocultural Ontologies, Perceptual Cues, and Biomarkers for Tibetan Tukdam Postmortem Meditative State” (2024)Tawni Tidwell et al, “Effect of Tibetan Herbal Formulas on Symptom Duration Among Ambulatory Patients with Native SARS-CoV-2 Infection: A Retrospective Cohort Study” (2024)Tawni Tidwell, “Tibetan Medical Paradigms for the SARS-CoV-2 Pandemic: Understanding COVID-19, Microbiome Links, and Its Sowa Rigpa Nosology” (2021)New open access book! Crafting Potency: Sowa Rigpa Artisanship Across the HimalayasTawni's research profile at the Center for Healthy MindsPlease note that Tawni is not taking new patients at this time, but she recommends the American Tibetan Medical AssociationBecome a paid subscriber on blackberyl.substack.com to unlock our members-only benefits, including downloading:Tawni Tidwell et al. “Chasing dön spirits in Tibetan medical encounters: Transcultural affordances and embodied psychiatry in Amdo, Qinghai” 2022.

A high calcium score, a stack of prescriptions, and the nagging sense that “healthy eating” wasn't working—David Etheridge's story captures what millions feel but rarely decode. When he shifted from chasing calories to controlling insulin, everything changed: he moved from a 12:12 rhythm to a 16:8 fasting window, led meals with protein and natural fats, saved carbs for later on the plate, and watched both cravings and brain fog fade. The scale moved, but the labs told the real story—A1C from 5.8 to 5.1, triglycerides from 285 to 72, and a dramatically improved lipid ratio.We dig into why this works. Intermittent fasting gives insulin time to fall, reigniting fat mobilization and cellular repair. Sequential eating blunts glucose spikes and steadies appetite. And building plates around eggs, meat, dairy, and vegetables respects how satiety actually functions. Along the way we confront the legacy of “low fat” guidance that pushed sugar and seed oils into everyday foods, trained us to graze, and stretched ingredient lists while shrinking satiety. David argues for flipping the pyramid: prioritize protein and real fats, add non-starchy vegetables for fiber and micronutrients, treat sugar as an occasional indulgence, and skip the ultra-processed traps.This isn't anti-medicine; it's pro-data. With medical oversight, David watched his markers improve and discussed next steps with a supportive clinician focused on outcomes, not dogma. Even with a high coronary calcium score, the goal becomes halting progression by lowering inflammation and improving insulin sensitivity. We also touch on how AI can translate cryptic test reports into plain English so patients ask better questions and make calmer choices. If you've tried to white-knuckle your way through snack culture, this conversation offers a clear, humane alternative: fewer eating windows, protein-first plates, simpler ingredients, and measurable wins. If this resonated, follow the show, share it with a friend who needs hope, and leave a review to help more people find the path back to metabolic health.Continue this conversation on SubStack: https://robertlufkinmd.substack.com Get 120 Biomarkers for $99 and CT Calcium scans anywhere in the US. https://www.vitalsvault.com/ Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/ Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmd Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Bluesky: ...

“Patients are waiting…”Those simple but profound words from Dr. Steve St. Onge set the tone for this conversation, and for why this work matters so deeply.Science has always fascinated me. I often joke that I'm not smart enough to be a scientist, but I have endless respect for the people who are, especially those who can take incredibly complex ideas and explain them in a way the rest of us can truly understand. This is why I know you're going to love my conversation with Dr. St. Onge. Steve is the Chief Business Officer at Clarametyx. Dr. St. Onge is a PharmD and MBA with more than 15 years of experience spanning clinical care, medical affairs, and leadership in biotechnology. What stands out most about Steve isn't just his impressive résumé, it's his ability to clearly explain the science, the strategy, and, most importantly, the urgency behind the work Clarametyx is doing.I first met Steve in person at the North American Cystic Fibrosis Conference (NACFC) in Seattle, where we had the opportunity to really connect and talk about Clarametyx's approach. Their work focuses on targeting biofilm-driven inflammation and progressive lung damage, an area of significant unmet need for people living with chronic respiratory diseases, including cystic fibrosis. In this conversation, Steve breaks down what biofilms are, why they're so difficult to treat, and how Clarametyx is thinking differently about tackling the inflammation and lung damage they cause.We also talk about the long road of drug development, the responsibility that comes with working in rare disease, and why the phrase “patients are waiting” isn't just a saying, it's a call to action. This episode is an honest, accessible, and hopeful look at science in motion, and at the people behind the research who are driven by the patients counting on progress.If you've ever wanted a clearer understanding of how innovative science moves from idea to impact—and why time matters so much, his is a conversation you won't want to miss. Please like, subscribe, and comment on our podcasts!Please consider making a donation: https://thebonnellfoundation.org/donate/The Bonnell Foundation website:https://thebonnellfoundation.orgEmail us at: thebonnellfoundation@gmail.com Watch our podcasts on YouTube: https://www.youtube.com/@laurabonnell1136/featuredThanks to our sponsors:Vertex: https://www.vrtx.comViatris: https://www.viatris.com/enRead us on Substack: https://substack.com/@lstb?utm_campaign=profile&utm_medium=profile-pageWatch our trailer of Embracing Egypt: https://youtu.be/RYjlB25Cr9Y

Perimenopause does not have to be the beginning of decline, but can instead be the start of your strongest chapter! In this inspiring success story, Louise, a leading expert for perimenopausal active women and runners, sits down with Jen, an everyday runner and mom who transformed her health, hormones, and body composition after years of frustration. Jen shares how anxiety, overtraining, fasting, and misinformation left her injured and stuck, despite doing everything she thought was “right.” The turning point came when she learned to fuel her body to build beautiful hormones and mitigate symptoms, apply specific targeted strength training, adjust her running, and work with her hormones instead of against them.Listeners will take away a powerful reminder that thriving in perimenopause does not require extreme diets or complicated protocols. Simple yet strategic consistent habits are often the most effective. This episode also highlights how community support, understanding your body's signals, and using whole foods strategically can improve energy, reduce inflammation, and restore confidence.If you feel discouraged by changing hormones, stubborn belly fat, being told there is nothing you can do about your genetic predispositions, or frustrating injuries that make you question your future as an active woman, Jen's story shows what is possible with the right approach, support, and mindset.RESOURCESLearn with my free nutrition guide and award-winning Academy to thrive through perimenopause with less stress: https://www.breakingthroughwellness.com/ Take Injury Prevention for Women Runners 30+ or my Female Runners Guide to Support Optimal Ferritin Masterclasses mentioned here.Grab a free monthly goal planning calendar & learn how to use it here.Get $25 off Function's comprehensive labs here or use code LVALENTINE11 Check out FullScript here where you can see curated supplement picks & save 20% off. A small portion of the sale goes back to support BTW.  Thank you!Save 20% off Kion's science-backed products. Code "LOUISE" saves on all future orders: https://www.getkion.com/pages/maximizingHighlights:(0:00) Intro(3:02) Retreat and power of supportive community(6:03) Rethinking running intensity and long-term health(13:05) Jen's journey into running for anxiety(17:37) Midlife wake-up call and quitting alcohol(22:20) Weight gain, injuries, and fasting mistakes(24:30) Severe injury and fear of never running again(27:11) Strength training and SI joint breakthroughs(35:31) Nutrition label awareness and inflammation insights(38:07) Simple fueling framework and sustainable habits(41:06) Bloodwork improvements using food(45:25) Genes, hormones, and personalized health approach(48:00) Biological age improvements and body transformation(51:53) Preview of part twoTune in weekly to "Maximizing Hormones, Physique, and Running Through Perimenopause" for our simple female-specific science-based revolution. Let's unlock our best with less stress!I'd love to connect! Email

Dr. Kevin Ko on Biomarkers, Oral Dysplasia, and the Limits of H&E DiagnosisChristine interviews Dr. Kevin Ko (DMD, MD), a pathologist at the BC Cancer Agency with training in oral and maxillofacial pathology, anatomic pathology, and dermatopathology. They discuss his ASDP 2025 lecture on using p53 in oral dysplasia as a potential new approach and the broader problem of diagnostic discordance and over-diagnosis when relying on H&E alone. Dr. Ko shares examples from practice, including recognizing oral porokeratosis (previously followed as dysplasia for years) and a chemotherapy-related lip lesion initially suspected to be severe dysplasia but supported by wild-type biomarker results and clinical history, resolving after stopping chemotherapy drugs. He emphasizes the need for reproducible biomarkers and possibly molecular-based classification to improve consistency and patient outcomes, while also describing the pressure to be near-perfect in pathology, the risk of burnout, and efforts to build sustainable systems (QA sessions, colleague consultation, protected time). The conversation closes with his approach to presentations as storytelling, interest in prospective multi-center research, and a final message about balancing perfectionism with rest while remaining open-minded to new diagnostic methods to improve patient care.00:00 Welcome & Meet Dr. Kevin Ko (DMD/MD, Dermpath at BC Cancer)01:00 The Controversial Idea: Using p53 Biomarkers in Oral Dysplasia01:18 Oral vs Skin Pathology: Discovering Porokeratosis in the Mouth02:07 Diagnostic Error & Overdiagnosis: Why Reproducible Biomarkers Matter05:19 Case Study: “Severe Dysplasia” vs Toxic Erythema of Chemotherapy —Context Changes Everything06:36 The Perfectionism Trap in Pathology (and Why 95% Isn't Good Enough)08:04 Burnout, QA Systems, and Building Sustainable Workflows09:14 Work–Life Balance, Kids, and Choosing Priorities (Family vs Research)11:14 How to Build a Great Talk: Storytelling, Cases, and Future Studies11:38 Final Takeaways: Balance, Open-Mindedness, and Better Diagnostics

The surgeon who spent 12 to14 hours a day in the operating room developed diabetes, uncontrolled high blood pressure, and an autoimmune disease that was eating away at his skull and it forced him to confront what medical school never taught him about actually staying healthy. I sat down with Dr. Darshan Shah, board-certified surgeon, founder of Next Health (one of the largest longevity clinic networks in America), and a doctor who had to reverse his own chronic disease to understand the massive gap between Western medicine and the science of health. We explore why surgeons and physicians become some of the sickest people in healthcare, how functional medicine differs from what you learn in medical school, why biomarker testing matters more than your doctor's "you're fine" assessment, and what root cause medicine actually looks like in practice. Dr. Shah also breaks down the AI revolution happening in cardiovascular imaging with Cleerly scans, how his new AI health dashboard reads your bloodwork and medical records to give you proactive guidance, why Yamanaka factors could regenerate damaged nerves in the brain, and what the future of personalized, preventive medicine looks like when you combine AI with real biological data. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The surgeon who developed the diseases he was treating 01:17 From trauma surgeon to longevity doctor: Dr. Shah's journey 04:18 Autoimmune disease, diabetes, and high blood pressure in a surgeon 10:30 Western medicine vs. the science of health 18:45 Why doctors don't learn prevention in medical school 35:20 Next Health clinics and democratizing longevity medicine 52:40 Biomarker testing and why "your labs are normal" is dangerous 01:03:52 AI health dashboard: uploading bloodwork and getting proactive guidance 01:06:45 Cleerly scans and reversing cardiovascular disease with AI imaging 01:10:08 Yamanaka factors, nerve regeneration, and the future of brain health _______ Thank you to our sponsors Function Health: https://www.functionhealth.com/louisanicola Timeline Mitopure: http://timeline.com/NEURO Ka'Chava: https://kachava.com and use code NEURO for 15% off your first order Wayfair: https://www.wayfair.com/ Fenix: https://www.fenixhealthscience.com/ Arey: https://arey.com/ and use code NEURO _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

What if the real lever for lasting weight loss isn't calories, but hunger itself? We sit down with Dr. Jason Fung to unpack why willpower-based diets fail and how hormones like insulin, cortisol, GLP-1, and sympathetic tone quietly set your “fat thermostat.” Instead of fighting biology, we explore how to work with it—lowering insulin, raising satiety, and removing the triggers that keep appetite stuck in overdrive.We dig into the three types of hunger that shape daily choices: homeostatic (physiological signals like ghrelin and leptin), hedonic (reward and emotion), and conditioned (learned cues from cars, screens, and social settings). Jason explains how ultra-processed foods exploit these systems by maximizing pleasure and minimizing fullness, why sleep and stress can spike cravings through cortisol, and how fasting strategically restores access to stored energy. We also discuss the difference between visceral and subcutaneous fat, why some people appear “skinny fat,” and how testing insulin, A1C, and C‑peptide gives a truer metabolic picture than BMI alone.From the failures of low-fat, calorie-counting eras to the surprising benefits seen with GLP-1 agonists, the throughline is clear: control hunger, and calories take care of themselves. You'll leave with three golden rules to start today—ditch ultra-processed foods, use fasting windows to lower insulin, and build a supportive circle that normalizes real food. It's a humane, science-driven framework that helps you stop battling your body and start resetting your internal settings.If this conversation helped reframe your approach to weight and health, follow the show, share it with a friend, and leave a quick review to help others find it.https://www.doctorjasonfung.com/Continue this conversation on SubStack: https://robertlufkinmd.substack.com Get 120 Biomarkers for $99 and CT Calcium scans anywhere in the US. https://www.vitalsvault.com/ Lies I Taught In Medical School : Free sample chapter- https://www.robertlufkinmd.com/lies/ Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmd Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd Bluesky: ...

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

Despite major advances in our understanding of the biology of mental health disorders,  there's no blood test or brain scan that will confirm if you have depression, anxiety, PTSD, or any other psychiatric illness.  And yet, the American Psychiatric Association recently announced that it will be including biomarkers for mental conditions in the next edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM), which guides diagnosis and treatment of mental illness. So how close are we to pinpointing the biological markers of mental illness, and what does that mean for diagnosis? It's complicated.  Host Flora Lichtman untangles some of this science with psychiatry researcher John Krystal. Guest: Dr. John Krystal is a professor of psychiatry, neuroscience, and psychology at the Yale School of Medicine. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Send a textIs AI in pathology actually improving diagnosis — or just adding complexity?In DigiPath Digest #37, we reviewed four recent publications covering AI-based biomarker quantification in glioblastoma, real-world digital workflow integration in prostate cancer, multimodal AI combining histopathology and genomics, and patient perspectives on AI in cancer diagnostics.This episode connects technical performance with something equally important: trust.Episode Highlights[00:02] Community & updates Digital Pathology 101 free PDF, upcoming patient-focused book, and global attendance.[04:07] AI-based image analysis in glioblastoma AI showed strong consistency with pathologists when quantifying Ki-67, P53, and PHH3. Significant biological correlations (Ki-67 ↔ PHH3, PHH3 ↔ P53) were detected by AI — not by manual assessment. Takeaway: computational quantification improves precision.[09:28] Real-world digital workflow + AI in prostate cancer (France) AI-pathologist concordance: • 93.2% (high probability cancer detection) • 99.0% (low probability slides) Gleason concordance: 76.6% 10% failure rate due to pre-analytical artifacts. Takeaway: infrastructure and sample quality still matter.[15:58] Multimodal AI (MARBIX framework) Combines whole slide images + immunogenomic data in a shared latent space using binary “monograms.” Performance in lung cancer: 85–89% vs 69–76% unimodal models. Takeaway: integrated data improves case retrieval and similarity reasoning.[22:13] AI-powered paper summary subscription introduced Structured summaries for busy professionals who want more than abstracts.[26:17] Patient roundtable on AI in pathology (Belgium) Patients expect: • Better accuracy • Faster turnaround • Stronger collaborationTrust is high when: • Algorithms use diverse datasets • Pathologists retain final responsibilityClinical validity mattered more than full algorithm transparency. Privacy concerns focused more on insurer misuse than cloud transfer.Key TakeawaysAI improves biomarker precision in glioblastoma.Digital pathology implementation works — but pre-analytics can limit AI performance.Multimodal AI represents the next meaningful step in precision diagnostics.Patients are not afraid of AI — they want validation, oversight, and governance.Human–AI collaboration remains central.If you're working in digital pathology, computational pathology, or precision oncology, this episode connects evidence, implementation, and patient perspective.Support the showGet the "Digital Pathology 101" FREE E-book and join us!

Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.In this Mind Moments episode, Jeff Chamberlain, PhD, joins the podcast during Duchenne Muscular Dystrophy Awareness Week to provide clinical and translational perspective on the evolving landscape of DMD biology and therapy. Chamberlain, professor at the University of Washington School of Medicine and Director of the Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center in Seattle, reflects on aspects of Duchenne pathophysiology that may still be underappreciated, including evidence that disease processes begin earlier than once recognized and the growing importance of immunologic factors in shaping progression and therapeutic response. The conversation also explores how neuromuscular specialists should approach treatment timing and combination strategies as gene-targeted therapies expand, the evolving interpretation and limitations of biomarkers such as creatine kinase and dystrophin expression, and what emerging gene therapy platforms may signal for care heading into 2026 and beyond.Looking for more Neuromuscular discussion? Check out the NeurologyLive® Neuromuscular clinical focus page.Episode Breakdown: 1:15 – Underrecognized aspects of DMD pathophysiology, including early onset and immunologic drivers 4:50 – Treatment timing, sequencing, and the rationale for combination strategies 8:00 – Neurology News Minute 10:30 – Clinical trial and real-world implications of dystrophin and CK as biomarkers 16:20 – Anticipated gene therapy innovation and safety considerations heading into 2026 The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: Regenxbio's MPS II Gene Therapy RGX-121 Hit With CRL FDA Accepts New Drug Application for Orexin Agonist Oveporexton in Narcolepsy Type 1, Grants Priority Review FDA Expands Indication for Pitolisant to Treat Cataplexy in Pediatric Narcolepsy Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.

Molly McVoy, MD, dives into the mental health crisis affecting teens, why anxiety and depression have risen dramatically, and shares breakthrough research using EEG biomarkers and self-management programs that help teens build resilience. Learn more about Daniel Simon, MDLearn more about Molly McVoy, MDNEW! View our Science@UH video podcast on YouTubeLearn more about the University Hospitals Research & Education Institute

By David Stephen who looks at biomarkers in this article. Will there ever be a biological test for human intelligence, to explore how to improve it in the age of AI? Like, would it ever be possible to test a human being for intelligence by some biological factor, and how to make it competitive against AI? The same question applies to mental disorders. Would there ever be biological tests, to know what therapies would work? These, at least for mental disorders, is what the American Psychiatric Association is seeking. Biomarkers for Psychiatry, Human Intelligence There is a recent [January 28, 2026] press release, APA Releases Roadmap for the Future of the DSM, stating that, "The American Psychiatric Association (APA) has released a series of papers offering a proposed roadmap for the future of the Diagnostic and Statistical Manual of Mental Disorders (DSM). The five papers, including the Initial Strategy for the Future of the DSM and four accompanying commentaries, are the result of the committee's year of structured debate and consideration of long-standing critiques and rapid scientific advances. They propose a forward-looking model for the evolution of the DSM. They also suggest changing the name from Diagnostic and Statistical Manual to Diagnostic and Scientific Manual to better reflect its scientific and global scope. The four accompanying papers address structure and dimensions of the DSM; the role of biomarkers and biological factors in diagnosis; vision for incorporating socioeconomic, cultural and environmental determinants of health and intersectionality; and the role of functioning and quality of life in psychiatric diagnosis." Conceptual Biomarkers and Theoretical Biological Factors for Psychiatric and Intelligence Nosology What are the options for biomarkers in the brain for mental disorders? Would they be different or similar to those for human intelligence? What are the universal components in the brain, for functions of human life and experiences? Can a model be developed on these components and their mechanisms, first to explain labels and next to scope out biomarkers? The problem before psychiatry is not just the distance to developing tests but to even describe what is happening in the brain for the labels of conditions. Mood disorders have several descriptions. But what are their components in the brain and the course of their actions. Answering these questions can put conditions in perspective as parallels are sought, before adventuring into biomarkers development. The same applies to human intelligence. Now, artificial intelligence is in an intense acceleration. There are valuable labor tasks that will be lost due to AI. And, because intelligence is the last frontier of superiority for humanity among organisms, it will be important to seek to map it, and explore it for problem-solving. This is the postulation in Conceptual Biomarkers and Theoretical Biological Factors for Psychiatric and Intelligence Nosology. The options are electrical and chemical signals as the components of functions in the brain. It states that neurons are conduits or bridges that signals use to carry out functions. It also states that signals are in sets in cluster of neurons. It is possible to use signals, conceptually, to explain and display all disorders in the DSM. It is also possible to use them to develop, explain, and display the two main types of human intelligence [improvement and operational], to ensure that options are broadened towards survival in the age of AI. This seminal work on conceptual brain science could be completed by August, 2026, moving psychiatry and intelligence forward, as well as neurology. David Stephen currently does research in conceptual brain science with focus on the electrical and chemical configurators for how they mechanize the human mind with implications for mental health, disorders, neurotechnology, consciousness, learning, artificial intelligence and nurture. He was a visiting scholar in m...

What if the way you age isn't just about time and genetics—but about your beliefs? What if your face, your energy, your vitality are shaped not only by biology but by what we might call your belief biology? In this episode, Harmony Slater sits down with Angelika Anagnostou, a practitioner of the Life Alignment methodology, to explore a radically different perspective on rejuvenation—one that blends the science of consciousness with the body's innate intelligence.   Disclaimer: The information shared in this episode is for educational and entertainment purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. The views and experiences expressed by the host and guest reflect their personal perspectives and practices and should not be interpreted as medical claims. Always consult a qualified healthcare provider before making changes to your health routine or discontinuing any medical treatment. Neither Finding Harmony Podcast, its host, guest, nor production team assume any responsibility or liability for any actions taken based on the content of this episode.   IN THIS EPISODE: What “belief biology” means and how your thoughts directly shape how you age The science of biophotons: how your cells literally emit light—and how your emotional state changes that light Why your body is your most faithful servant and responds to every instruction you give it The morphogenetic field: the collective agreement about aging that most of us unconsciously follow Ellen Langer's “Clockwise” study: how elderly participants reversed biological markers of aging How emotions get stored in the face and body—and how to release them The difference between fighting aging and reconnecting with your original energetic blueprint Why presence and the power of the present moment are the keys to rejuvenation Harmony's personal story of healing her eyesight without surgery Practical steps you can start today: observing the thoughts you direct toward your body How the Life Alignment method creates a meditative space for reprogramming the body The seven codes for rejuvenation and radiance (preview)   Chapters 00:00 Welcome to Finding Harmony: Ancient Wisdom Meets Modern Life 00:42 Belief Biology: Rethinking Aging, Beauty & Vitality 04:04 Meet Angelica: Why Rejuvenation Starts From Within 07:20 The Age ‘Download': How Birthdays Trigger Beliefs in the Body 09:53 Mantras, Biomarkers & the Body Listening to Your Commands 13:37 Stress, Presence & Life Force: The Fast Track to Looking Younger 16:11 Biophotons and Inner Light: The Science Behind Radiance 18:34 Life Alignment Method: Quiet the Mind, Reprogram the Body 20:13 Your Original Blueprint: Sacred Geometry, Energy Codes & Choosing Your Form 22:33 Consistency Creates Change: Building a New Identity Beyond Old Conditioning 25:36 Where Science Is Pointing: Quantum Physics and the Future of Healing 26:45 Biohacking vs Mind: The Energy Field Behind Healing 27:15 Ellen Langer's ‘Clockwise' Study: Reversing Aging Through Context 29:00 DNA, Entanglement & the ‘Biology of Belief' Explained 30:07 The Aging Script: How Midlife Retraction Programs the Body 31:37 Cancel the ‘Shut Down' Narrative: Watch Your Self-Talk 32:36 Field Consciousness & Radical Healing Stories (Organs, Skin, Vitality) 34:20 Beyond Genetics: You're the Engineer of Your DNA & Patterns 35:32 What to Expect in the Masterclass: Emotions in the Face + ‘Spiritual Botox' 37:18 How the Group Chooses the Focus Area + Spinal Energetics Recalibration 39:30 Dates, Details & One Practice to Start Now: Catch the Thought Loop 42:05 Mirror Work & Playfulness: Reprogramming Beauty Beliefs (Salma Example) 44:24 Final Invitation + Podcast Wrap: Where Rejuvenation Really Begins   GUEST BIO: Angelika Anagnostou is a practitioner of the Life Alignment methodology who helps people reconnect with their innate intelligence and energetic blueprint. Her work focuses on using consciousness, energy, and direct experience to facilitate deep healing, rejuvenation, and personal transformation.   Find Angelika on IG: https://www.instagram.com/living.alchemy Find Angelika online: http://www.iamwellness.in   SPECIAL OFFER: Join Harmony and Angelika for the Inner Rejuvenation Codes masterclasses: February 21 and March 7, 2026. Plus a 6-week program launching at the end of March 2026. https://harmonyslater.kit.com/inner-rejuvenation-codes-mc FIND Harmony online: https://harmonyslater.com/ Harmony on IG: https://www.instagram.com/harmonyslaterofficial/ Finding Harmony Podcast on IG: https://www.instagram.com/findingharmonypodcast/ FREE Manifestation Activation: https://harmonyslater.kit.com/manifestation-activation

Think your brain has to slow down with age? We push back hard with science, stories, and a step-by-step plan that has helped patients regain clarity in weeks, not years. Our guest, Dr Majid Fotuhi, a Harvard- and Hopkins-trained neurologist who has treated thousands of patients, explains why common forgetfulness isn't the same as cognitive decline and how simple daily choices can restore sharpness at any age.We break brain health down to four core levers: increase blood flow, reduce inflammation, enhance the brain's cleaning systems, and minimize plaques and tangles. Then we map those levers to five daily pillars you can actually do: exercise, sleep, nutrition, stress reduction, and learning. You'll hear why exercise is the highest-yield habit for cognition, how BDNF acts like fertilizer for the hippocampus, and what happens when sugar spikes and insulin resistance quietly shrink your memory center. We also get practical about sustainable nutrition, from curbing glucose swings to deciding whether keto is worth it for your lifestyle.Beyond biology, we dig into the mindsets that keep the brain young. Boredom—of the unplugged, daydreaming kind—can unlock creativity and problem solving. A clear sense of purpose measurably lowers dementia and stroke risk while making healthy choices easier to keep. We share the telltale red flags (like repeating questions) versus normal lapses (like misplacing keys), plus the personalized assessment approach that uncovered treatable factors in patients who feared Alzheimer's. If you want a realistic timeline, expect noticeable gains in about 12 weeks when you dial in the five pillars.Ready to build a resilient, younger brain? Follow the five pillars, personalize your plan, and start today with one small step—take a brisk walk, protect your sleep window, or learn something challenging you actually enjoy. If this conversation helped you, tap follow, share it with a friend who needs hope, and leave a quick review so more people can find it.https://drfotuhi.com/Continue this conversation on SubStack: https://robertlufkinmd.substack.com Get 120 Biomarkers for $99 and CT Calcium scans anywhere in the US. https://www.vitalsvault.com/ Win a Signed Copy of Lies I Taught in Medical School :https://robert-lufkin.mykajabi.com/pages/review-kit Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmd Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd ...

In Episode 126 Joe speaks with Sue Peschin, President and CEO of the Alliance for Aging Research, about what Alzheimer's and dementia look like in the real world and how policy determines who gets help and when.  Sue explains the mission and 40–year history of the Alliance for Aging Research and lays out the scope of the Alzheimer's crisis in plain language: who is affected, how dementia types differ, and why neuropsychiatric symptoms like agitation, psychosis, and depression are so often ignored in policy and practice. They discuss why early detection matters more than ever now that disease-modifying therapies and amyloid inhibitors exist, and why so many cases are still missed in primary care. Sue walks through new blood biomarkers, digital cognitive assessments, and how Medicare coverage, CED restrictions, and the proposed ASAP Act will shape access to testing and treatment. Joe and Sue also dig into Coverage with Evidence Development (CED) in Medicare, whether CMS is overstepping what Congress intended under Section 1801, and how restrictive coverage decisions have limited access to Alzheimer's drugs to a tiny fraction of eligible patients. Finally, they talk about caregiver burden, stigma around behavioral symptoms, and what families and clinicians can realistically do today. If you care about Alzheimer's, dementia, early detection, blood biomarkers, Medicare coverage, CED, the ASAP Act, primary care, caregiver burden, vascular dementia, and aging research, this episode connects the science with the politics and the lived experience. In This ConversationJoe and Sue cover: What the Alliance for Aging Research is and why it focuses on “gap” aging and brain health issues How many Americans are living with Alzheimer's and dementia, including younger-onset cases The difference between Alzheimer's, vascular dementia, and other dementias, and why neuropsychiatric symptoms matter Why early and accurate detection is critical, even before someone qualifies for a disease-modifying therapy New tools: blood-based biomarkers, digital assessments, PET scans, and when they are used How Medicare coverage, Coverage with Evidence Development (CED), and the ASAP Act affect access to diagnostics and treatments The tension between FDA's role on safety and effectiveness and CMS's role on cost control and coverage Timestamps (Audio platforms) 0:00 Intro and Sue's background / Alliance for Aging Research 5:30 How big is the Alzheimer's and dementia problem 10:30 Why early detection matters and why diagnoses are still missed 18:30 Neuropsychiatric symptoms, stigma, and caregiver burden 26:30 Blood biomarkers, digital tools, and primary care 33:30 The ASAP Act and Medicare coverage for biomarkers 38:30 Coverage with Evidence Development (CED) and Section 1801 45:00 How to get involved and where to find resources Key Takeaways Alzheimer's is one of several dementias, and many patients have mixed dementia (Alzheimer's plus vascular changes). Early detection is vital, not only for disease-modifying therapies, but to rule out other treatable causes and to help families plan. New blood biomarkers and digital assessments could make detection cheaper and easier, but coverage and adoption lag behind the science. Medicare's CED policy has sharply limited access to Alzheimer's therapies despite FDA approval and labeled indications. The ASAP Act aims to secure Medicare coverage for Alzheimer's blood-based biomarkers without waiting on slow guideline processes. About Our GuestSue Peschin is President and CEO of the Alliance for Aging Research, the leading nonprofit focused on advancing science, policy, and education to improve healthy aging and access to care. At the Alliance, Sue has driven national work on Alzheimer's, dementia, neuropsychiatric symptoms, Medicare policy, CED reform, and aging research, empowering older adults and caregivers to advocate for better care.

Dr. Greg Cooper and Dr. David G. Coughlin discuss the role of αSyn-SAAs in diagnosing DBL and their relationship with Alzheimer's disease biomarkers.  Show citation: Coughlin DG, Jain L, Khrestian M, et al. CSF α-Synuclein Seed Amplification Assays and Alzheimer Disease Biomarkers in Dementia With Lewy Bodies: Presentation and Progression. Neurology. 2025;105(12):e214346. doi:10.1212/WNL.0000000000214346 Show transcript:  Dr. Greg Cooper: Hi, this is Dr. Greg Cooper. I just finished interviewing Dr. David Coughlin for this week's Neurology Podcast. For today's Neurology Minute, I'm hoping you can tell us the main points of your paper. Dr. David Coughlin: The main points of this paper in my mind is that α-Synuclein seed amplification assays from cerebrospinal fluid samples is useful in confirming the presence of synuclein pathology in people with clinically suspected dementia with Lewy bodies. But also that, for people who have synuclein positivity, that the presence of Alzheimer's disease mixed pathology is associated with a worse cognitive progression over time. Dr. Greg Cooper: Thank you Dr. Coughlin, for that summary and for all of your work on this topic. Please check out this week's podcast to hear the full interview and read the full article published in Neurology, CSF α-Synuclein Seed Amplification Assays and Alzheimer's Disease Biomarkers in Dementia with Lewy Bodies. Thank you.

Dr. Greg Cooper talks with Dr. David G. Coughlin about the role of αSyn-SAAs in diagnosing dementia with Lewy bodies and their relationship with Alzheimer disease biomarkers.  Read the related article in Neurology®.  Disclosures can be found at Neurology.org. 

In this episode, Dr. Jockers sits down with Dr. Jack Wolfson, board-certified cardiologist and founder of Natural Heart Doctor, to challenge everything you think you know about heart disease. You'll discover why the "100-year heart" isn't a myth but a design principle. They unpack how true health is built through eat well, live well, think well — and why testing, not guessing, changes everything.   You'll learn why lowering cholesterol or blood pressure with medication isn't the same as addressing root causes. Dr. Wolfson explains the real role of inflammation, oxidative stress, metabolic health, and advanced biomarkers in cardiovascular risk. They also discuss fasting, nutrient-dense ancestral nutrition, and why seafood and organ meats play a powerful role in heart longevity.   You'll also explore overlooked drivers of heart disease, including sleep quality, sunlight exposure, mold toxicity, oral health, nervous system alignment, and mental well-being. The conversation reveals how purpose, community, and emotional resilience directly impact cardiovascular outcomes. This episode reframes heart health as a whole-life strategy, not just a lab number.   In This Episode:  00:00 Introduction: The Myth of Sudden Health Decline 00:26 Welcome Back: Introducing Dr. Jack Wolfson 00:57 The 100 Year Heart: A Natural Approach to Cardiovascular Health 04:05 Conventional Medicine vs. Natural Health 07:51 The Importance of Lab Testing and Biomarkers 14:07 Optimal Nutrition for Heart Health 19:11 Lifestyle Strategies for Longevity 25:28 The Power of Positive Thinking and Community 29:12 Conclusion: Resources and Final Thoughts   If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday.   BON CHARGE's Red Light Face Mask helps to restore glow, calm the complexion, and soften the visible signs of aging – all from the comfort of home. Order yours today and start seeing the amazing skincare benefits. Get 15% off now when you go to https://boncharge.com/ and use my exclusive promo code DRJOCKERS.   OneSkin: Get 15% off OneSkin with the code DRJOCKERS at https://www.oneskin.co/DRJOCKERS  #oneskinpod   Superpower:  Head to Superpower.com and use code JOCKERS at checkout for $20 off your membership. Live up to your 100-Year potential. #superpowerpod     "Your heart is designed to live to 100 and beyond. Chronic disease is preventable, not inevitable."      Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio   Resources:   Connect with Dr. Jack Wolfson: Website - https://drjackwolfson.com/   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

Show notes: (0:00) Intro (1:14) What led Dr. Cole to functional medicine and early telehealth (6:13) Why many "healthy" people still feel unwell (11:15) The top 3 blood tests you should ask for (18:58) How inflammation is the real issue (28:21) The "Inflammatory Core 4" foods to cut out (35:26) Carbs, ketosis, and finding what works for your body (40:45) Surprising household toxins that may be harming your health (45:20) Practical steps to reduce exposure and feel better faster (48:48) Where to find Dr. Cole (49:58) Outro Who is Dr. Will Cole?   Dr. Will Cole is a leading functional medicine expert who consults people around the world via webcam, having started the first functional medicine telehealth centers in the world. Named one of the top 50 functional and integrative doctors in the nation, Cole specializes in clinically investigating underlying factors of chronic disease and customizing a functional medicine approach for thyroid issues, autoimmune conditions, hormonal imbalances, digestive disorders, and brain problems.   He is the host of the popular The Art of Being Well podcast and the New York Times bestselling author of Intuitive Fasting, Gut Feelings, Ketotarian, and The Inflammation Spectrum.   Connect with Dr. Cole Website: https://drwillcole.com/ LinkedIn: https://www.linkedin.com/in/drwillcole/ Instagram: https://www.instagram.com/drwillcole   Tune in: https://drwillcole.com/podcast/   Grab a copy: https://drwillcole.com/books-home-page/ Links and Resources: Peak Performance Life - https://buypeakperformance.com/ Peak Performance on Facebook - https://www.facebook.com/livepeakperformance/ Peak Performance on Instagram - https://www.instagram.com/livepeakperformance

Brent Ness, CEO and President of Aclarion,  highlights the challenges of diagnosing and treating chronic lower back pain, a leading driver of healthcare costs and opioid addiction. Traditional MRI and CT imaging do not reveal the biochemical source of pain within spinal discs, leading to misdiagnosis and unsuccessful treatment. The Aclarion technology uses MR spectroscopy to measure pain-causing biomarkers and, through a cloud-based, AI-powered SaaS model, analyzes the raw data and sends the physician a report within minutes. Brent explains, "The diagnosis and accurate treatment planning of back pain are incredibly complex. And when you think about pain management physicians, rehab, all the way up to spine surgery identifying the source of pain accurately leads to better treatment and then obviously better outcomes.There are 266 million people around the world who suffer from chronic low back pain. So I'm not talking about the kind that you had a rough weekend skiing, golfing, or hiking, and you're a little sore. I'm talking about the kind that keeps people from participating in a meaningful life. " "When you think about the joints and the sources of blood flow, the nerves that are all around your spinal cord, the vertebral columns, and there's just a lot of moving parts and a lot of really, let's just call it high-value real estate that can actually be the source of pain. And really, our superpower is to help physicians see the invisible. Meaning that normally when you go to the doctor, and they do a workup on you, they'll use an MRI or a CT scanner. And those modalities are really good at pinpointing anatomical issues that might be causing pain. What we do is we use MR spectroscopy, not to make a picture of your back, but rather to measure the biomarker content inside the discs that are invisible on a normal MRI. And as it turns out, what's inside your disc can actually be the source of pain." #ACON #CLARITYtrial #lowbackpain #spinesurgery #MRSpectroscopy #Biomarkers #AugmentedIntelligence #innovation #ChronicPain #BackPain #MedicalTechnology #AI #HealthcareInnovation #SpineCare #MRI #PainManagement #DigitalHealth #Diagnostics #HealthTech #PatientCare aclarion.com Download the transcript here

Brent Ness, CEO and President of Aclarion,  highlights the challenges of diagnosing and treating chronic lower back pain, a leading driver of healthcare costs and opioid addiction. Traditional MRI and CT imaging do not reveal the biochemical source of pain within spinal discs, leading to misdiagnosis and unsuccessful treatment. The Aclarion technology uses MR spectroscopy to measure pain-causing biomarkers and, through a cloud-based, AI-powered SaaS model, analyzes the raw data and sends the physician a report within minutes. Brent explains, "The diagnosis and accurate treatment planning of back pain are incredibly complex. And when you think about pain management physicians, rehab, all the way up to spine surgery identifying the source of pain accurately leads to better treatment and then obviously better outcomes.There are 266 million people around the world who suffer from chronic low back pain. So I'm not talking about the kind that you had a rough weekend skiing, golfing, or hiking, and you're a little sore. I'm talking about the kind that keeps people from participating in a meaningful life. " "When you think about the joints and the sources of blood flow, the nerves that are all around your spinal cord, the vertebral columns, and there's just a lot of moving parts and a lot of really, let's just call it high-value real estate that can actually be the source of pain. And really, our superpower is to help physicians see the invisible. Meaning that normally when you go to the doctor, and they do a workup on you, they'll use an MRI or a CT scanner. And those modalities are really good at pinpointing anatomical issues that might be causing pain. What we do is we use MR spectroscopy, not to make a picture of your back, but rather to measure the biomarker content inside the discs that are invisible on a normal MRI. And as it turns out, what's inside your disc can actually be the source of pain." #ACON #CLARITYtrial #lowbackpain #spinesurgery #MRSpectroscopy #Biomarkers #AugmentedIntelligence #innovation  #ChronicPain #BackPain #MedicalTechnology #AI #HealthcareInnovation #SpineCare #MRI #PainManagement #DigitalHealth #Diagnostics #HealthTech #PatientCare aclarion.com  Listen to the podcast here

Artificial intelligence is rapidly changing how we understand our health — not just how we feel today, but how fast we're actually aging.On this episode of Live Long, host Peter Bowes continues his personal experiment with Hundred, the AI-powered longevity platform that combines advanced blood testing, wearable data and personalized insights to track biological age and guide smarter health decisions.After introducing the app in an earlier conversation, Peter reconnects with Hundred's founder, Tyler Smith, to go deeper into the idea of a “health operating system” — essentially a personal doctor in your pocket. Together they explore how continuous testing and AI analysis could help prevent disease, spot risks earlier, and motivate lasting behavior change — while also addressing the realities of over-testing, false alarms, privacy concerns and health anxiety.Peter also shares the results of his own first round of testing, what surprised him most, and how he's using the data to shape his approach to longevity and healthy aging.-----JOIN HUNDREDOptimize your healthspan and potentially lower your biological age.  Tyler and the team at HUNDRED are offering $75 in credit for add-on tests and supplements from the HUNDRED marketplace when you sign up at hundred.com/livelongpodcastThis podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. Visit our SHOP for more details: https://healthspan-media.com/live-long-podcast/shop/Time-line Mitopure (a highly pure form of Urolithin A) boosts the health of our mitochondria – the battery packs of our cells – and improves muscle strength. Time-line is offering LLAMA listeners a 10% discount on its range of products – Mitopure powders, softgels & skin creams.  Use the code LLAMA at checkout-Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts SpotifyEnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountPartiQlar supplementsEnhance your wellness journey with pure single ingredients. 15% DISCOUNT - use code: MASTERAGING15Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Your skin is screaming what your blood work is whispering. Dr. Shawana Vali transformed how I understand the visible signs of internal dysfunction, & it's not what the beauty industry wants you to hear. Those wrinkles, breakouts, & pigmentation issues? They're your body's warning system telling you about adrenal fatigue, hormone imbalances, & inflammatory cascades happening deep in your tissues. Ready to look 5 years younger by treating the root cause instead of chasing symptoms? CLICK HERE TO BECOME GARYS VIP!: ⁠⁠https://bit.ly/4ai0Xwg⁠⁠ Connect with Dr. Shawana Vali Website: ⁠⁠https://bit.ly/467cGNl⁠⁠  YT: ⁠⁠https://bit.ly/3NuM9TU⁠⁠  IG: ⁠⁠https://bit.ly/4a6SMV5⁠⁠  TT: ⁠⁠https://bit.ly/4quCzij⁠⁠  FB: ⁠⁠https://bit.ly/4jN5ICM⁠⁠  LI: ⁠⁠https://bit.ly/4pPtqj8⁠⁠  Thank you to our partners H2TABS: “ULTIMATE10” FOR 10% OFF: ⁠⁠https://bit.ly/4hMNdgg⁠⁠ BODYHEALTH: “ULTIMATE20” FOR 20% OFF: ⁠⁠http://bit.ly/4e5IjsV⁠⁠ BAJA GOLD: "ULTIMATE10" FOR 10% OFF: ⁠⁠https://bit.ly/3WSBqUa⁠⁠ SNOOZE: LET'S GET TO SLEEP!: ⁠⁠https://bit.ly/4pt1T6V⁠⁠ COLD LIFE: THE ULTIMATE HUMAN PLUNGE: ⁠⁠https://bit.ly/4eULUKp⁠⁠ WHOOP: JOIN AND GET 1 FREE MONTH!: ⁠⁠https://bit.ly/3VQ0nzW⁠⁠ AION: “ULTIMATE10” FOR 10% OFF: ⁠⁠https://bit.ly/4h6KHAD⁠⁠ A-GAME: “ULTIMATE15” FOR 15% OFF: ⁠⁠http://bit.ly/4kek1ij⁠⁠ PEPTUAL: “TUH10” FOR 10% OFF: ⁠⁠https://bit.ly/4mKxgcn⁠⁠ CARAWAY: “ULTIMATE” FOR 10% OFF: ⁠⁠https://bit.ly/3Q1VmkC⁠⁠ HEALF: 10% OFF YOUR ORDER: ⁠⁠https://bit.ly/41HJg6S⁠⁠ RHO NUTRITION: “ULTIMATE15” FOR 15% OFF: ⁠⁠https://bit.ly/44fFza0⁠⁠ GOPUFF: GET YOUR FAVORITE SNACK!: ⁠⁠https://bit.ly/4obIFDC⁠⁠ GENETIC METHYLATION TEST (UK ONLY): ⁠⁠https://bit.ly/48QJJrk⁠⁠ GENETIC TEST (USA ONLY): ⁠⁠⁠https://bit.ly/3Yg1Uk9⁠⁠ Watch  the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YT: ⁠⁠https://bit.ly/3RPQYX8⁠⁠ Podcasts: ⁠⁠https://bit.ly/3RQftU0⁠⁠ Connect with Gary Brecka IG: ⁠⁠https://bit.ly/3RPpnFs⁠⁠ TT: ⁠⁠https://bit.ly/4coJ8fo⁠⁠X: ⁠⁠https://bit.ly/3Opc8tf⁠⁠ FB: ⁠⁠https://bit.ly/464VA1H⁠⁠ LI: ⁠⁠https://bit.ly/4hH7Ri2⁠⁠ Website: ⁠⁠https://bit.ly/4eLDbdU⁠⁠ Merch: ⁠⁠https://bit.ly/4aBpOM1⁠⁠ Newsletter: ⁠⁠https://bit.ly/47ejrws⁠⁠ Ask Gary: ⁠⁠https://bit.ly/3PEAJuG⁠⁠ Timestamps 00:00 Intro of Show 02:20 Healing the Skin from the Inside Out 06:41 Biomarkers for Accelerated Skin Aging 10:17 Link between Stress and Skin 12:51 Clean Movement in the Beauty Industry 18:04 Inflammatory Skin Conditions 19:13 What's Causing Skin to Age Quickly? 24:55 Exosomes in Skincare Products 32:02 Collagen, Elastin, Fibrin Definitions 36:26 What Happens to Women's Skin during Perimenopause? 43:37 Hormone Replacement Therapy and Peptides on Women 48:03 New Breed Skin Technology 54:05 Less is More for Skincare 1:04:09 What does it mean to you to be an Ultimate Human? The information provided here is for general informational purposes only and should not be considered as medical or clinical advice. It is not intended to diagnose, treat, cure, or prevent any health condition, and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of your physician or other qualified health provider with any questions you may have regarding a medical condition or health objectives. The use of any information provided is solely at your own risk, and the provider of this information is not liable for any consequences arising from its use. Disclosure: Some links to certain products or services are affiliate links, meaning we may earn a commission. Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation. Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered promotional in nature. Learn more about your ad choices. Visit megaphone.fm/adchoices

When it comes to longevity, most of the research feels clear around exercise and nutrition. We know how they affect aging and the prevention of the four diseases that kill most people: heart disease, cancer, metabolic disease, and dementia. But where do sleep, stress, and lifestyle actually fit into that picture?  In Part 1 of the 2026 Body Blueprint, Ted explained why most men over 40 age faster than they should.   In Part 2, he broke down why weight loss alone doesn't equal health.   In Part 3, he showed how men should train to preserve muscle and strength with minimal time.   In Part 4, he explained why cardio and cardiovascular fitness are essential for longevity—even if you already lift.   In Part 5, he shared a clear, evidence-based approach to nutrition that supports metabolic health, longevity, and fat loss without quitting your social life or eliminating foods you enjoy.  In Part 6, Ted turns to the most underestimated drivers of how you age: sleep, stress, and lifestyle. He explains why these factors are harder to quantify but just as powerful, how they quietly influence disease risk and recovery, and why ignoring them can undermine even the best training and nutrition plan. This episode puts the final pieces of the longevity puzzle into place.  You'll learn:    How poor sleep drives fat gain, insulin resistance, and hormonal decline  The surprising link between sleep, pain sensitivity, and chronic injuries  How chronic stress accelerates aging even in mentally tough high achievers  Objective ways to measure stress using heart rate, HRV, and blood pressure  The difference between managing stress symptoms vs. fixing root causes    What Ted discusses in this episode:  (00:00) Introduction (04:35) The Importance of Sleep for Longevity (08:42) Hormones and Sleep (16:42) Sleep Hygiene Tips (24:52) The Role of Caffeine and Alcohol in Sleep (29:35) Understanding and Managing Stress (30:08) Understanding Chronic Stress (30:42) The Importance of Recovery (32:07) Defining Stress and Its Effects (35:13) Tracking Stress with Biomarkers (40:08) Strategies for Managing Stress (47:05) The Power of Social Connections (53:12) Conclusion and Final Thoughts

On this episode of The Dr. Hyman Show, I'm rejoined by psychiatrist and Harvard professor Dr. Chris Palmer for a conversation that challenges how we've been taught to think about mental illness. For decades, psychiatry has focused on managing symptoms—often without asking what's actually driving them. We discuss a different way of understanding mental health, one that looks beyond diagnostic labels and considers how whole-body biology influences brain function, resilience, and recovery.  Watch the full conversation on YouTube or listen wherever you get your podcasts. In this conversation, we explore: • Why mental illness is rising alongside obesity, diabetes, and other chronic diseases • How whole-body biology influences mood, focus, and emotional resilience • The link between inflammation, metabolic dysfunction, and conditions like depression and bipolar disorder • How nutrition, testing, and lifestyle changes can support real recovery If mental health has ever felt close to home for you or someone you care about, this conversation is meant to offer clarity, compassion, and a place to start. This episode was recorded live at the Eudēmonia Summit, a conference exploring the future of health, longevity, and well-being. Learn more at eudemonia.net. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hymanhttps://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, BON CHARGE, Qualia, Paleovalley, Pique and Korrus. Receive 35% off a subscription at timeline.com/drhyman. Upgrade your routine. Head to boncharge.com/hyman and use code DRMARK for 15% off. Go to qualialife.com/hyman and use code HYMAN at checkout for an extra 15% off. Head to paleovalley.com and use code HYMAN20 for 20% off your first order. Secure 20% off your order plus a free starter kit at piquelife.com/hyman.Upgrade your lighting. Enjoy 15% off at korrus.com/drhyman. (0:00) Introduction to mental health crisis and guest Dr. Christopher Palmer (1:31) Eudaimonia Summit and psychiatric revolution (3:06) Traditional and systemic views on psychiatric disorders (7:23) Misconceptions and stigma surrounding mental disorders (10:15) The impact of childhood experiences on mental health (13:28) Root causes of mental illness: Inflammation and brain dysfunction (21:23) Metabolic dysfunction in mental illness (24:15) Significance of metabolism in mental health (27:47) Metabolic nutritional psychiatry and premature mortality (32:34) The mental health revolution and metabolic treatments (34:16) Ketogenic diet as a potential treatment for mental disorders (37:18) Functional and network medicine in mental health (41:13) Biomarkers and potential treatments in metabolic mental health (49:07) Ketogenic therapy and its anti-inflammatory effects (50:12) Historical and emerging paradigms in psychiatry (54:38) Integrating functional medicine into mainstream psychiatry (56:20) Addressing chronic disease in national health discussions (58:22) Closing remarks and further resources (59:02) Podcast outro and call to action