Podcasts about biomarkers

Alzheimer's and dementia aren't just a matter of age or genetics. Increasing evidence shows that metabolic health—particularly insulin resistance—plays a key role in cognitive decline.In this episode of A Whole New Level, neurologist and bestselling author Dr. David Perlmutter joins Mike Haney to explore the links between brain health and metabolism. They discuss the role of insulin resistance and inflammation in Alzheimer's disease, the biomarkers that can reveal risk decades before symptoms, and how lifestyle interventions can dramatically change your trajectory.Topics include:Key biomarkers for assessing brain health: fasting insulin, A1C, homocysteineWhy targeting inflammation may matter more than targeting amyloid plaquesThe promise and limitations of GLP-1 medications for dementia and Parkinson'sPractical steps you can take now to protect long-term cognitive functionSign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl

In this episode of the WHOOP Podcast, Founder and CEO, Will Ahmed, and Chief Product Officer, Ed Baker introduce WHOOP Advanced Labs — an all new feature that integrates 65 blood biomarkers with WHOOP data to deliver personalized coaching, clinician-reviewed reports, and actionable health insights. Learn exclusive insight about how WHOOP Advanced Labs empowers members to take control of their health, encourage lifestyle changes, and move closer to our mission at WHOOP to add 1 billion healthy years to people's lives.Sign up for WHOOP Advanced Labs(00:00) Introduction to WHOOP Advanced Labs(02:51) Biomarkers, Bloodwork, & WHOOP Data(04:03) Uploading Past Bloodwork: How It Works(07:54) WHOOP Advanced Labs Subscription with Quest Diagnostics(12:03) Analyzing the 65 Key Biomarkers with WHOOP(13:34) Healthspan: Applying Advanced Labs Data to Weekly Habits(14:36) Bloodwork and Biomarkers as a Baseline For Sleep, Recovery, and Health(15:43) Data Made Simple(17:13) The Bigger Picture: The Future of WHOOP Advanced Labs(18:45) Privacy Assurance & Protecting User Data(19:30) Impact of Advanced Labs on Daily HabitsThe first 100 members to tap this link will unlock early access to WHOOP Advanced Labs.**Open the link on the same device as your WHOOP app.Support the showFollow WHOOP: www.whoop.com Trial WHOOP for Free Sign up for WHOOP Advanced Labs Instagram TikTok YouTube X Facebook LinkedIn Follow Will Ahmed: Instagram X LinkedIn Follow Kristen Holmes: Instagram LinkedIn Follow Emily Capodilupo: LinkedIn

2025 ACC Scientific Statement on Inflammation & Cardiovascular Disease

You've seen the headlines about new blood tests and treatments for Alzheimer's, Parkinson's, and ALS, but what's the science behind those breakthroughs? In this episode, HudsonAlpha scientists Ben Henderson, PhD, and Bri Rogers, PhD, break down the role of biomarkers and genetics in early detection and treatments of neurodegenerative diseases. Discover how research being conducted today is creating real hope for tomorrow.To go behind the scenes and learn more about this episode, visit “Beyond the Headlines: How Biomarkers and Genetics are Changing Neurodegenerative Disease Research.” If you prefer to watch your podcasts, head over to our Youtube channel. Thanks for listening! We're now on YouTube- follow us here. To receive episode updates and bonus material, subscribe to our mailing list here.

In this episode of the Let's Talk Brain Health Podcast, we welcome Dr. Kellyann Niotis, MD, the world's first fellowship-trained preventive neurologist, who shares her insights on early detection and risk reduction for neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Lewy body dementia. Dr. Niotis discusses the emerging field of preventive neurology, the role of blood biomarkers and genetic testing, and the importance of lifestyle choices in maintaining brain health. She also highlights the impact of cholesterol management, sleep studies, and the significance of personalized care approaches. Join us as we dive into a comprehensive discussion about the future of brain health and the proactive steps we can take today for healthier brains tomorrow.00:00 Introduction to Dr. Kellyann Niotis, MD02:47 What is Preventive Neurology?06:08 The Role of Biomarkers in Early Detection13:52 Lifestyle Modifications and Brain Health17:12 Cholesterol and Brain Health24:15 The Impact of Statins on Cognition26:05 Underutilized Tools in Brain Health30:11 Rapid Fire Questions and Final ThoughtsResourcesConnect with Kellyann on Instagram @drkellyannniotis Visit her website ​​and learn more about her new clinic on their websiteResearchLearn more about the research-informed brain health risks mentioned in this episode from the “Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission” ReportRead more about Dr. Lisa Misconi's research on how estrogen receptors are unregulated in perimenopause in this research article 

In this episode, we explore how Explainable AI (XAI) is revolutionizing drug development, rare disease research, and precision medicine.Our guest, Frédéric Parmentier, Vice President of Data Science at Ariana Pharma, shares how their Explainable Artificial Intelligence (XAI) platform, KEM (Knowledge Extraction and Management), helps uncover critical biomarker signatures in small cohort clinical trials. Unlike traditional black box AI models, XAI delivers transparent, interpretable results that regulators and clinicians can trust—making it a game-changer for early-phase drug development, rare disease trials, and personalized medicine.We dive into:Why Explainable AI in clinical trials is essential for regulatory acceptance and scientific validation.How XAI can identify biomarkers of best responders in cohorts as small as 20–100 patients.Real-world examples where AI revealed insights that traditional statistics missed.The future of AI in drug development, precision medicine, and rare disease research.The difference between black box AI vs. Explainable AI in healthcare and why transparency matters.If you work in biopharma, clinical research, AI-driven healthcare, or drug discovery, this episode will give you powerful insights into how XAI can accelerate development, reduce trial failures, and enable personalized treatment strategies.About the PodcastAI for Pharma Growth is a podcast focused on exploring how artificial intelligence can revolutionise healthcare by addressing disparities and creating equitable systems. Join us as we unpack groundbreaking technologies, real-world applications, and expert insights to inspire a healthier, more equitable future.This show brings together leading experts and changemakers to demystify AI and show how it's being used to transform healthcare. Whether you're in the medical field, technology sector, or just curious about AI's role in social good, this podcast offers valuable insights.AI For Pharma Growth is the podcast from pioneering Pharma Artificial Intelligence entrepreneur Dr. Andree Bates created to help organisations understand how the use of AI based technologies can easily save them time and grow their brands and business. This show blends deep experience in the sector with demystifying AI for all pharma people, from start up biotech right through to Big Pharma. In this podcast Dr Andree will teach you the tried and true secrets to building a pharma company using AI that anyone can use, at any budget. As the author of many peer-reviewed journals and having addressed over 500 industry conferences across the globe, Dr Andree Bates uses her obsession with all things AI and futuretech to help you to navigate through the, sometimes confusing but, magical world of AI powered tools to grow pharma businesses. This podcast features many experts who have developed powerful AI powered tools that are the secret behind some time saving and supercharged revenue generating business results. Those who share their stories and expertise show how AI can be applied to sales, marketing, production, social media, psychology, customer insights and so much more. Dr. Andree Bates LinkedIn | Facebook | Twitter

Rheum to Breathe Rx Update ILD Treatment and Guidelines Part 3: ILD Assessment and Management including: Biomarkers in ILD (Dr. Elena Joerns), How to Assess ILD in Patients (Dr. Janet Pope) and Management of SSc ILD (Dr. Alicia Hinze)

As part of the September issue, the European Respiratory Journal presents the latest in its series of podcasts. Deputy Chief Editor Don Sin interviews Associate Editor Marcus Mall about neutrophil-derived biomarkers in bronchiectasis, as discussed in his review article in this issue of the ERJ: https://doi.org/10.1183/13993003.00081-2025 Cite this podcast as: ERJ Podcast September 2025: Neutrophil-derived biomarkers in bronchiectasis. Eur Respir J 2025; 55: 25E6603. [https://doi.org/10.1183/13993003.E6603-2025]

Longevity is a hot health topic, but what factors move the needle on not only how long you live but how long you experience relatively good health? Some lab and other tests can help assess how healthy you're aging and provide context for what lifestyle and other changes to make. Dr. Matt Kaeberlein and Mike Haney discuss the tests that help assess healthy aging, how mental health and physical health are intricately connected, which lifestyle factors might expand your health span, and where the research stands on various longevity topics.Get a Free Guide to Understanding Your Lab Results: https://levels.link/wnl

If you were given some of the worst news in the world, wouldn't you expect your doctors to use every tool available?What if one of those tools could save millions of lives—and the science is already here?The world's largest medical cannabis and cancer study—10,000 papers, ranked in the top 5% globally—shows overwhelming evidence that cannabis has medical benefits. If fully embraced, its impact on patients and medicine could be transformative. As science continues to unfold, sometimes it takes skeptics to dive deep and uncover what's truly there, even when powerful interests push back.This week we sit down with Ryan Castle, Research Director at Whole Health Oncology Institute, to discuss:Medical cannabis: efficacy, placebo, and why it matters less than you thinkHow this study is being used in rescheduling effortsHow vested interests fuel anti-cannabis researchChapters00:00 Introduction to Medical Cannabis Research03:06 Ryan Castle's Journey into Cannabis Research05:58 The Meta-Analysis Process Explained09:00 Understanding the Data and Its Implications11:54 Skepticism and the Shift in Perspective15:01 Consensus in Medical Cannabis Research18:04 Nuances in Cancer Treatment and Cannabis20:55 Biomarkers and Inflammatory Responses22:56 Exploring Cannabis and Cancer Outcomes29:37 Bridging the Gap: Patient-Reported Outcomes35:32 The Future of Medical Cannabis Research45:34 The Cancer Playbook: Empowering Patients SummaryIn this episode, Bryan Fields and Kellan Finney engage with Ryan Castle, Research Director at Whole Health Oncology Institute, to explore the evolving landscape of medical cannabis research. Ryan shares his journey from skepticism to advocacy, detailing the extensive meta-analysis he conducted on the efficacy of cannabis in treating various symptoms and conditions, particularly in oncology. The conversation delves into the challenges of measuring effectiveness, the importance of patient-reported outcomes, and the need for a shift in medical perspectives towards cannabis as a legitimate treatment option. Ryan emphasizes the potential impact of policy changes and the importance of transparency in research, while also discussing the Cancer Playbook initiative aimed at empowering patients with data-driven insights. TakeawaysRyan Castle initially set out to prove that cannabis doesn't work.His extensive research revealed that cannabis is effective for a wide range of conditions.The meta-analysis included over 10,000 studies and 800,000 data points.Cannabis showed efficacy not just for symptoms but also for cancer treatment.Patient-reported outcomes are crucial for understanding cannabis effectiveness.The study found that cannabis can help reduce opioid dependency.There is a significant need for a shift in medical perspectives on cannabis.Transparency in research is essential for building trust in findings.The health impact assessment could reveal the broader benefits of cannabis.The Cancer Playbook initiative aims to empower patients with data-driven insights.Guest Linkshttps://wholehealthoncologyinstitute.com/Our LinksBryan Fields on TwitterKellan Finney on TwitterThe Dime on TwitterExtraction Teams: Want to cut costs and get more out of every run? Unlock hidden revenue by extracting more from the same input—with Newton Insights.At Eighth Revolution (8th Rev), we provide services from capital to cannabinoid and everything in between in the cannabinoid industry.The Dime is a top 5% most shared  global podcastThe Dime is a top 10 Cannabis Podcast The Dime has a New Website. Shhhh its not finished.

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Prognostic Value of Biomarkers in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy.

Dr. Luisa María Rivera is a critical biocultural anthropologist whose work examines how social inequality, trauma, and structural violence shape reproductive and maternal–infant health. She integrates ethnographic research with epigenomic and other molecular approaches to trace how stress during development can reverberate across generations and to understand the implications of these findings for health policy. Luisa earned her B.A. from Harvard (2008), an M.P.H. from the University of Minnesota (2015), and a Ph.D. in Anthropology from Emory University (2022). She is currently a Neukom Postdoctoral Fellow at Dartmouth College, mentored by Dr. Zaneta Thayer (Anthropology) and Dr. Brock Christensen (Geisel School of Medicine). Her research includes long-term work in post-war communities in Guatemala and with historically marginalized communities in the United States. Luisa previously joined the Sausage of Science “Hackademics” series in Episode 114, Dissertation Research in the Time of COVID-19. ------------------------------ Find the paper discussed in this episode: Vlasac, I. M., Stolrow, H. G., Thayer, Z. M., Christensen, B. C., & Rivera, L. (2025). DNA-based cell typing in menstrual effluent identifies cell type variation by sample collection method: toward noninvasive biomarker development for women's health. Epigenetics, 20(1), 2453275. https://doi.org/10.1080/15592294.2025.2453275 ------------------------------ Contact Luisa: E-mail: Luisa.Rivera@dartmouth.edu website: https://luisamariarivera.com/ Google Scholar ------------------------------ Contact the Sausage of Science Podcast and Human Biology Association: Facebook: facebook.com/groups/humanbiologyassociation/, Website: humbio.org, Twitter: @HumBioAssoc Chris Lynn, Host Website: cdlynn.people.ua.edu/, E-mail: cdlynn@ua.edu, Twitter:@Chris_Ly Cristina Gildee, Co-host, SoS Co-Producer, HBA Junior Fellow Website: cristinagildee.org, E-mail: cgildee@uw.edu,

In this rerun episode, we dig into the science behind what's happening inside our bodies with registered sports dietitian Ashley Reaver. Ashley highlights five key biomarkers that endurance athletes should pay attention to—explaining why they matter, what healthy ranges look like, and what steps we can take if our numbers are off. From performance to recovery, these biomarkers influence how well we train and how resilient we are to stress and fatigue. Ashley also shares practical strategies athletes can use to optimize their nutrition and overall health. With her background as a private practice dietitian, UC Berkeley instructor, and lead nutritional scientist at InsideTracker, Ashley brings both scientific depth and real-world application. Whether you're chasing new PRs or aiming for long-term health, this conversation offers valuable insights every runner can put into practice.  Check out her private practice Episode Sponsors: Janji, Use code TRAILRUNNER for 10% off Amazfit - T-Rex 3: Get 15% off JAMBAR: 20% off with code TRN20 Liquid IV, get 20% off your first order with code TRAILRUNNER Get the NEW "1 > 0" running hat HERE.  Limited supply

Relationship goals meet biohacking in this revealing conversation about how Sage Workinger-Brecka and Gary Brecka synchronize their health protocols while respecting their genetic differences. In this episode, they also answer your most-burning questions on children's nutrition, hormonal imbalance, ADHD symptoms, and mitochondrial health. Bonus: they share the exact mineral cocktail they drink daily, including their morning routines, which has been a game-changer for sustained energy without the afternoon crash.   Join the Ultimate Human VIP community for Gary Brecka's proven wellness protocols!: https://bit.ly/4ai0Xwg Connect with Sage Workinger-Brecka Website: http://bit.ly/3HGwUos Instagram: http://bit.ly/45PCvSz Facebook: http://bit.ly/4lZ4SlS Thank you to our partners H2TABS: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg BODYHEALTH: “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV BAJA GOLD: "ULTIMATE10" FOR 10% OFF: https://bit.ly/3WSBqUa EIGHT SLEEP: SAVE $350 ON THE POD 4 ULTRA WITH CODE “GARY”: https://bit.ly/3WkLd6E COLD LIFE: THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp WHOOP: JOIN AND GET 1 FREE MONTH!: https://bit.ly/3VQ0nzW MASA CHIPS: 20% OFF FIRST ORDER: https://bit.ly/40LVY4y VANDY: “ULTIMATE20” FOR 20% OFF: https://bit.ly/49Qr7WE AION: “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD A-GAME: “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij CARAWAY: “ULTIMATE” FOR 10% OFF: https://bit.ly/3Q1VmkC HEALF: 10% OFF YOUR ORDER: https://bit.ly/41HJg6S BIOPTIMIZERS: “ULTIMATE” FOR 15% OFF: https://bit.ly/4inFfd7 RHO NUTRITION: “ULTIMATE15” FOR 15% OFF: https://bit.ly/44fFza0 GOPUFF: GET YOUR FAVORITE SNACK!: https://bit.ly/4obIFDC GENETIC TEST: ⁠https://bit.ly/3Yg1Uk9 Watch  the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps 00:00 Intro of Show 02:43 Most Overlooked Thing by Couples 07:15 How to Improve Health and Relationship 09:09 What Does Your Fatigue Mean? 14:08 Habits that Influence Your Energy, Focus, and Mood 24:51 Top 3 Biomarkers to Track 26:37 Debunking Health Myths 34:39 Starting a Health Journey 37:41 How to Increase Mitochondrial Function Naturally 40:36 Best Supplements for Children 47:13 Biohacking during Pregnancy 50:00 Influencing Children to Take More Nutrient-Dense Foods 53:11 Supporting Children with ADHD 58:09 Coffee Alternatives to Boost Productivity 1:05:00 Overcoming Itchy Skin 1:08:45 Fasting and Weight Training  1:13:36 Biomarkers for Hormone Panel Test 1:18:30 Join The Ultimate Human VIP The Ultimate Human with Gary Brecka Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The Content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. Learn more about your ad choices. Visit megaphone.fm/adchoices

My guest is Michael Snyder, PhD, professor of genetics at Stanford and an expert in understanding why people respond differently to various foods, supplements, behavioral and prescription interventions. We discuss how to optimize your health and lifespan according to what type of glucose responder you are, which genes you express, your lifestyle and other factors. Dr. Snyder also explains the key ages when you need to be particularly mindful about following certain health practices. We also discuss how people respond in opposite ways to different fiber types. This episode ought to be of interest and use to anyone seeking to understand their unique biological needs and how to go about meeting those needs. Sponsors AGZ by AG1: https://drinkag1.com/huberman Wealthfront*: https://wealthfront.com/huberman David: https://davidprotein.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman *This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Timestamps 00:00 Michael Snyder 03:33 Healthy Glucose Range, Continuous Glucose Monitors CGM, Hemoglobin A1c 09:02 Individual Variability & Food Choice, Glucose Spikes & Sleepiness 12:18 Sponsors: AGZ by AG1 & Wealthfront 15:16 Glucose Spikes, Tools: Post-Meal Brisk Walk; Soleus “Push-Ups”; Exercise Snacks 21:06 Glucose Dysregulation, Diabetes & Sub-Phenotypes, Tool: Larger Morning Meal 28:34 Exercise Timing, Muscle Insulin Resistance 30:49 Diabetes Subtyping, Weight, Glucose Control; Incretins 35:41 GLP-1 Agonists, Diabetes, Tool: Muscle Maintenance & Resistance Training 38:40 Metformin, Berberine, Headaches 41:01 GLP-1 Agonists, Cognition, Longevity, Tool: Habits Support Medication; Cycling 47:41 Subcutaneous vs Visceral Fat, Organ Stress 49:10 Sponsors: David & Eight Sleep 51:58 Meal Timing & Sleep, Tools: Post-Dinner Walk, Routines, Bedtime Consistency 57:16 Microbiome, Immune System & Gut; Diet & Individual Variability 1:02:52 Fiber Types, Cholesterol & Glucose, Polyphenols 1:09:50 Food As Medicine; Fiber, Microbiome & Individual Variability; Probiotics 1:18:48 Sponsor: Function 1:20:35 Profiling Healthy Individuals, Genomes, Wearables 1:26:31 Whole-Body MRIs, Nodules, Healthy Baseline, Early Diagnosis 1:34:07 Sensors, CGM, Sleep, Heart Rate Variability HRV, Tools: Mindset Effects, Increase REM 1:39:30 HRV, Sleep, Exercise, Tool: Long Exhales; Next-Day Excitement & Sleep 1:42:48 Organ Aging, “Ageotypes”; Biological Age vs Chronological Age 1:49:41 Longevity, Health Span, Genetics, Blue Zones 1:52:19 Epigenetics, Viral Infection & Disease 1:58:54 ALS, Heritability; Neuroprotection, Nicotine 2:03:47 Air Quality, Allergies, DEET & Pesticides, Inflammation, Mold; Microplastics 2:15:02 Single-Drop Blood Test & Biomarkers, Wearables, Observational Trials 2:20:33 Acupuncture, Blood Pressure 2:26:40 Immersive Events & Mental Health Benefits 2:34:59 Data, Nutrition & Lifestyle; Siloed Health Care vs Personalized Medicine 2:43:06 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Social Media, Neural Network Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

If you found out earlier on in your youth that you actually have a genetic propensity toward addiction, would you have made decisions a lot differently? Addiction is a bio-psycho-social model, but we don't really look at the biology part of it. Sometimes, we have to look at the physiology of things to understand addiction better. And there has to be a paradigm shift in thinking about how we operate and exist in this world. On today's episode, Duane speaks with Dr. Evelyn Higgins about genes and biomarkers, how they influence our behavior, how they play out in addiction, and why knowing about this part of ourselves is an important step in addiction treatment and recovery. Dr. Evelyn Higgins is the founder and CEO of Wired For Addiction and a recognized international expert in the epidemiology of addiction. With 34 years in clinical practice, Dr. Higgins has spent over 16 years dedicated to research and development in the science of addiction recovery, and she finds herself at the nexus of epigenetics, neuroscience, and addiction. In this episode, you will hear:What it means to look at errors in genetic codingEpigenetics and aberrant behaviorsWhy addiction is not a moral flaw, but a diseaseThe first step is getting objective information.The common genetic markers of addictionHow seeing addiction from a biological perspective impacts the familiesFollow and Review:We'd love for you to follow us if you haven't yet. Click that purple '+' in the top right corner of your Apple Podcasts app. We'd love it even more if you could drop a review or 5-star rating over on Apple Podcasts. Simply select “Ratings and Reviews” and “Write a Review” then a quick line with your favorite part of the episode. It only takes a second and it helps spread the word about the podcast.Supporting Resources:Wired For AddictionDr. Higgins' TEDTalk: NovusMindfulLife.comhttps://www.theaddictedmind.com/community Follow and Review: We'd love it even more if you could drop a review or 5-star rating over on Apple Podcasts. Simply select “Ratings and Reviews” and “Write a Review” then a quick line with your favorite part of the episode. It only takes a second and it helps spread the word about the podcast. If you live in California and are looking for counseling or therapy please check out Novus Mindful Life Counseling and Recovery CenterNovusMindfulLife.comWe want to hear from you. Leave us a message or ask us a question: https://www.speakpipe.com/addictedmindDisclaimerSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Drs. Petri and Fava review non-invasive biomarkers in systemic lupus erythematosus, including urine proteomics.

What if aging wasn't just something that happens to us, but something science could actually slow down? That's the question at the heart of today's conversation with Dr. Matt Kaeberlein, who's a leading scientist and longevity researcher at the University of Washington.Dr. Kaeberlein has spent decades decoding the biology of aging, from cellular mechanisms to practical strategies that could extend not just how long we live, but how well we live. In this episode, we talked about surprising connections between aging and brain health, and looked into the research around lithium and Alzheimer's to see what the latest science is telling us about extending healthspan.It is an informative discussion on whether aging itself can be slowed or reversed. If you're curious about how close we really are to changing the rules of aging, this could be worth a watch.Chapters00:00 – Introduction & The Biology of Aging Across Species10:57 – The Struggles of Change, GLP-1 Drugs & The Power of Sleep14:33 – The Hallmarks of Aging21:52 – Funding Issues23:22 – The Truth About Anti-Aging Drugs27:22 – Biological Age Testing 48:23 – Biomarkers, Advanced Testing & The Limits of Diagnostics01:02:50 – Micronutrient Testing and Supplements01:07:11 –  NAD, Smarter Longevity Choices01:18:05 –  Lithium's Secret Role in Aging and Memory Loss01:27:00 – Foundations of Longevity01:57:37 - Ovarian Aging02:01:02 – Closing Thoughts & Where to Find the Guest Guest's socials + websiteYouTube: https://www.youtube.com/@optispanX: https://x.com/mkaeberlein?lang=enWebsite: https://www.optispan.life/ Kayla's social + website:Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter: https://x.com/femalelongevity Website: https://www.kaylabarnes.com/Follow Her Female Protocol: https://www.protocol.kaylabarnes.com/Become a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

What if aging wasn't just something that happens to us, but something science could actually slow down? That's the question at the heart of today's conversation with Dr. Matt Kaeberlein, who's a leading scientist and longevity researcher at the University of Washington.Dr. Kaeberlein has spent decades decoding the biology of aging, from cellular mechanisms to practical strategies that could extend not just how long we live, but how well we live. In this episode, we talked about surprising connections between aging and brain health, and looked into the research around lithium and Alzheimer's to see what the latest science is telling us about extending healthspan.It is an informative discussion on whether aging itself can be slowed or reversed. If you're curious about how close we really are to changing the rules of aging, this could be worth a watch.Chapters:00:00 – Introduction & The Biology of Aging Across Species10:57 – The Struggles of Change, GLP-1 Drugs & The Power of Sleep14:33 – The Hallmarks of Aging21:52 – Funding Issues23:22 – The Truth About Anti-Aging Drugs27:22 – Biological Age Testing 48:23 – Biomarkers, Advanced Testing & The Limits of Diagnostics01:02:50 – Micronutrient Testing and Supplements01:07:11 –  NAD, Smarter Longevity Choices01:18:05 –  Lithium's Secret Role in Aging and Memory Loss01:27:00 – Foundations of Longevity01:57:37 - Ovarian Aging02:01:02 – Closing Thoughts & Where to Find the Guest Guest's socials + website:YouTube: https://www.youtube.com/@optispanX: https://x.com/mkaeberlein?lang=enWebsite: https://www.optispan.life/ Kayla's social + website:Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter: https://x.com/femalelongevity Website: https://www.kaylabarnes.com/Follow Her Female Protocol: https://www.protocol.kaylabarnes.com/Become a Member of Kayla's Female Longevity Membership: https://kayla-barnes-lentz.circle.so/checkout/become-a-member

In this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Eric Verdin, President and CEO of the Buck Institute for Research on Aging. Eric discusses the science behind therapeutic plasma exchange (TPE) and its potential to slow biological aging in humans. The conversation explores findings from a recent clinical trial, including measurable age reversal using epigenetic clocks.Eric explains how removing and replacing plasma can dilute pro-aging factors in the blood, a concept inspired by earlier animal studies on parabiosis. He also describes why rigorous, placebo-controlled human trials are crucial for validating longevity interventions and distinguishing the field from hype-driven wellness trends.The episode also highlights how omics data, such as metabolomics and proteomics, are shaping a new era of precision aging research. Eric emphasizes the value of lifestyle interventions as a foundation and sees future opportunities in combining TPE with personalized strategies to extend healthspan.  Guest-at-a-Glance

- American Society of Clinical Oncology (ASCO) 2025 Annual Meeting: Triple Negative Breast Cancer Updates - New Research on Triple Negative Breast Cancer Presented at ASCO - Triple Negative Breast Cancer-Specific Treatment Updates - Young Adults & Older Adult Updates - Updates on Clinical Trials in Advancing Treatment Choices - The Increasing Role of Diagnostic Testing, Biomarkers & Genetic Testing in Informing Treatment Options - Investigational New Therapies in Clinical Trials - New Developments in the Prevention & Management of Treatment Side Effects, Symptoms, Discomfort, Quality of Life & Pain - Key Questions to Ask Your Health Care Team - Guidelines for Preparing for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Adherence, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- American Society of Clinical Oncology (ASCO) 2025 Annual Meeting: Triple Negative Breast Cancer Updates - New Research on Triple Negative Breast Cancer Presented at ASCO - Triple Negative Breast Cancer-Specific Treatment Updates - Young Adults & Older Adult Updates - Updates on Clinical Trials in Advancing Treatment Choices - The Increasing Role of Diagnostic Testing, Biomarkers & Genetic Testing in Informing Treatment Options - Investigational New Therapies in Clinical Trials - New Developments in the Prevention & Management of Treatment Side Effects, Symptoms, Discomfort, Quality of Life & Pain - Key Questions to Ask Your Health Care Team - Guidelines for Preparing for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Adherence, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

- American Society of Clinical Oncology (ASCO) 2025 Annual Meeting: Triple Negative Breast Cancer Updates - New Research on Triple Negative Breast Cancer Presented at ASCO - Triple Negative Breast Cancer-Specific Treatment Updates - Young Adults & Older Adult Updates - Updates on Clinical Trials in Advancing Treatment Choices - The Increasing Role of Diagnostic Testing, Biomarkers & Genetic Testing in Informing Treatment Options - Investigational New Therapies in Clinical Trials - New Developments in the Prevention & Management of Treatment Side Effects, Symptoms, Discomfort, Quality of Life & Pain - Key Questions to Ask Your Health Care Team - Guidelines for Preparing for Telehealth/Telemedicine Appointments, Including Technology, Prepared List of Questions, Adherence, Follow-Up Care & Discussion of OpenNotes - Questions for Our Panel of Experts

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/EFP865. CME/MOC/NCPD/AAPA credit will be available until August 20, 2026.Leveraging Biomarkers to Optimize Treatment Outcomes With ATTs in Early Symptomatic Alzheimer's Disease: New Data and Clinical Pearls From AAIC 2025 In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/EFP865. CME/MOC/NCPD/AAPA credit will be available until August 20, 2026.Leveraging Biomarkers to Optimize Treatment Outcomes With ATTs in Early Symptomatic Alzheimer's Disease: New Data and Clinical Pearls From AAIC 2025 In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/EFP865. CME/MOC/NCPD/AAPA credit will be available until August 20, 2026.Leveraging Biomarkers to Optimize Treatment Outcomes With ATTs in Early Symptomatic Alzheimer's Disease: New Data and Clinical Pearls From AAIC 2025 In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/EFP865. CME/MOC/NCPD/AAPA credit will be available until August 20, 2026.Leveraging Biomarkers to Optimize Treatment Outcomes With ATTs in Early Symptomatic Alzheimer's Disease: New Data and Clinical Pearls From AAIC 2025 In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA information, and to apply for credit, please visit us at PeerView.com/EFP865. CME/MOC/NCPD/AAPA credit will be available until August 20, 2026.Leveraging Biomarkers to Optimize Treatment Outcomes With ATTs in Early Symptomatic Alzheimer's Disease: New Data and Clinical Pearls From AAIC 2025 In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

In this episode, host Saranya Ravindran is joined by Toby Maher to explore the often-overlooked world of interstitial lung diseases. From clarifying common misconceptions to highlighting AI innovations and personalised treatments, the series dives deep into what clinicians need to know about these serious lung conditions. Whether you're new to interstitial lung diseases or experienced in respiratory care, this series offers timely insights and expert takeaways. Timestamps: 00:00: Introduction 00:41: Challenges in early diagnosis 03:22: ILD biomarkers 05:49: The overlap with autoimmune diseases 09:16: AI in ILD detection

In this episode, host Saranya Ravindran is joined by Toby Maher to explore the often-overlooked world of interstitial lung diseases. From clarifying common misconceptions to highlighting AI innovations and personalised treatments, the series dives deep into what clinicians need to know about these serious lung conditions. Whether you're new to interstitial lung diseases or experienced in respiratory care, this series offers timely insights and expert takeaways. Timestamps: 00:00: Introduction 00:40: Mainstays of treatment 04:42: Limitations of current antifibrotics 07:50: The future of ILD personalised care 13:40: Are we close to the reversal of fibrosis? 15:52: A message for clinicians

Alzheimer's is not inevitable—and it may even be optional. In this groundbreaking episode, you'll learn how to prevent, slow, and in some cases reverse cognitive decline using strategies that also enhance brain optimization, metabolism, and longevity. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey is joined by Dr. Dale Bredesen, a world-renowned neurologist and leading Alzheimer's researcher who has published over 240 peer-reviewed papers. Dr. Bredesen has spent decades proving that Alzheimer's is not a one-pathway disease but a network failure driven by inflammation, toxins, and mitochondrial dysfunction. His protocol has helped thousands of patients regain memory, extend healthspan, and reclaim brain performance. Together, they unpack how biohacking tools like fasting, ketosis, supplements, sleep optimization, cold therapy, and functional medicine can rewire neuroplasticity, protect mitochondria, and keep the brain in “connection mode” instead of decline. You'll hear why the pharmaceutical industry resists these solutions, how toxins like Paraquat and mold fuel cognitive decline, and what young people can do right now to bulletproof their brains for life. This episode is essential listening if you care about hacking human performance, upgrading metabolism, or extending longevity. You'll walk away with practical strategies you can use today—whether that means optimizing your mitochondria with nootropics, strengthening resilience with smarter not harder recovery, or fueling your brain with Danger Coffee. You'll Learn: • Why Alzheimer's can begin as early as your 20s and what biomarkers to track • The seven major drivers of Alzheimer's and how to reverse them with biohacking strategies • How APOE4 genetics, toxins, and inflammation accelerate brain aging—and what to do about it • The role of mitochondria, ketosis, and fasting in restoring brain optimization and neuroplasticity • Why prevention is exponentially easier than reversal and the top three actions you should start in your 20s • How to avoid “learned helplessness” in medicine and reclaim control over your brain span and longevity Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. Keywords: Alzheimer's prevention biohacking, APOE4 genetics risk, mitochondrial dysfunction brain, network insufficiency model, cognitive decline reversal protocol, neuroplasticity longevity strategies, mild cognitive impairment treatment, subjective cognitive impairment biomarkers, ketoflex 12/3 diet, mycotoxins and Alzheimer's, Paraquat Parkinson's risk, mitochondrial transfusion therapy, fasting neuroprotection, ketosis brain optimization, natokinase soft plaque removal, sleep apnea cognitive decline, functional medicine Alzheimer's, hippocampal volume preservation, nootropics cognitive resilience, learned helplessness medicine Thank you to our sponsors! EMR-Tek | Go to https://www.emr-tek.com/DAVE and use code DAVE for 40% off.fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE. OneSkin | Get 15% off your first purchase at https://oneskin.co/ASPREY with code ASPREY. Resources: • Dale's Website: https://www.apollohealthco.com/dr-bredesen/ • Danger Coffee: https://dangercoffee.com/DAVE15 • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 — Trailer 1:10 — Introduction 2:43 — Personal Story 7:52 — APOE4, Genetics, and Drug Development 11:37 — Pharma, Media, and Pushback 17:13 — Prevention, Stages, and Biomarkers 23:34 — Causes and Mechanisms 30:24 — Parkinson's, Toxins, and Mitochondria 37:17 — Longevity, Biohacking, and Protocols 44:11 — AI, Data, and Future Treatments 54:11 — Case Studies and Success Stories 1:03:00 — Detox, Mold, and Environmental Triggers 1:12:00 — Neuroplasticity and Brain Regeneration 1:20:00 — Hormones, Supplements, and Personalized Hacks 1:29:00 — Cortisol, Addison's, and AI Protocols 1:38:00 — Large-Scale Trials and Global Impact 1:45:00 — Final Takeaways See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Ina Stelzer, Ph.D., explores how the maternal immune system adapts to support a healthy pregnancy and how disruptions can lead to complications like preterm birth. Her lab identifies early immune changes linked to spontaneous preterm birth and investigates the role of the maternal brain in regulating immune responses. Stelzer uses advanced technologies like mass cytometry and spatial proteomics to map immune and molecular changes in pregnancy, integrating these data with transcriptomics and mouse models. Her team studies how antidepressants affect immune signaling during pregnancy and examines the impact of social and behavioral factors. These insights may reveal biomarkers and therapeutic targets for improving maternal and fetal health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40773]

In this episode, host Saranya Ravindran is joined by Toby Maher to explore the often-overlooked world of interstitial lung diseases. From clarifying common misconceptions to highlighting AI innovations and personalised treatments, the series dives deep into what clinicians need to know about these serious lung conditions. Whether you're new to interstitial lung diseases or experienced in respiratory care, this series offers timely insights and expert takeaways. Timestamps: 00:00: Introduction 02:00: ILD landscape: UK versus USA 04:33: What falls under the ILD umbrella? 06:38: Idiopathic pulmonary fibrosis 07:58: Understanding different patient profiles 09:28: Early clinical signs of ILD

In this episode, host Saranya Ravindran is joined by Toby Maher to explore the often-overlooked world of interstitial lung diseases. From clarifying common misconceptions to highlighting AI innovations and personalised treatments, the series dives deep into what clinicians need to know about these serious lung conditions. Whether you're new to interstitial lung diseases or experienced in respiratory care, this series offers timely insights and expert takeaways.

Ina Stelzer, Ph.D., explores how the maternal immune system adapts to support a healthy pregnancy and how disruptions can lead to complications like preterm birth. Her lab identifies early immune changes linked to spontaneous preterm birth and investigates the role of the maternal brain in regulating immune responses. Stelzer uses advanced technologies like mass cytometry and spatial proteomics to map immune and molecular changes in pregnancy, integrating these data with transcriptomics and mouse models. Her team studies how antidepressants affect immune signaling during pregnancy and examines the impact of social and behavioral factors. These insights may reveal biomarkers and therapeutic targets for improving maternal and fetal health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40773]

Ina Stelzer, Ph.D., explores how the maternal immune system adapts to support a healthy pregnancy and how disruptions can lead to complications like preterm birth. Her lab identifies early immune changes linked to spontaneous preterm birth and investigates the role of the maternal brain in regulating immune responses. Stelzer uses advanced technologies like mass cytometry and spatial proteomics to map immune and molecular changes in pregnancy, integrating these data with transcriptomics and mouse models. Her team studies how antidepressants affect immune signaling during pregnancy and examines the impact of social and behavioral factors. These insights may reveal biomarkers and therapeutic targets for improving maternal and fetal health. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40773]

This episode of Space Nuts is brought to you with the support of NordVPN. Protect your online privacy and access with our special deal by visiting www.nordvpn.com/spacenuts or use the promo code SPACENUTS at checkout.Cosmic Mysteries: Little Red Dots and Astronomical AchievementsIn this exciting episode of Space Nuts, hosts Heidi Campo and Professor Fred Watson explore the latest discoveries and breakthroughs in astronomy. From the intriguing mystery of the "little red dots" observed by the James Webb Space Telescope to the historic appointment of the first female Astronomer Royal, this episode is packed with cosmic insights and fascinating stories.Episode Highlights:- The Mystery of the Little Red Dots: Fred delves into the enigma surrounding the bright, red galaxies identified by the James Webb Space Telescope. He explains their significance, formation theories, and how they might provide a glimpse into the early universe, dating back nearly 12 billion years.- Celebrating Michelle Doherty: The hosts proudly announce the appointment of Michelle Doherty as the first female Astronomer Royal in over 300 years. Fred highlights her groundbreaking contributions to planetary science and her pivotal role in major NASA missions, including the Cassini mission to Saturn.- Detecting Life on Mars: A groundbreaking new test developed by researchers in the UK shows promise for detecting signs of life on Mars using existing rover technology. Fred discusses how this test could revolutionize our search for extraterrestrial life by analyzing chemical bonds in cell membranes.- SpaceX's Starship Launches: The episode wraps up with an update on SpaceX's ambitious Starship program, discussing the challenges and successes of recent launches. Fred reflects on the engineering feats and the importance of these missions for future lunar exploration.For more Space Nuts, including our continuously updating newsfeed and to listen to all our episodes, visit our website. Follow us on social media at SpaceNutsPod on Facebook, X, YouTube Music Music, Tumblr, Instagram, and TikTok. We love engaging with our community, so be sure to drop us a message or comment on your favorite platform.If you'd like to help support Space Nuts and join our growing family of insiders for commercial-free episodes and more, visit spacenutspodcast.com/aboutStay curious, keep looking up, and join us next time for more stellar insights and cosmic wonders. Until then, clear skies and happy stargazing.Got a question for our Q&A episode? https://spacenutspodcast.com/amaBecome a supporter of this podcast: https://www.spreaker.com/podcast/space-nuts-astronomy-insights-cosmic-discoveries--2631155/support.

Using biomarker testing and APOE genotyping to determine patient eligibility for amyloid-targeting therapies. Credit available for this activity expires: 8/19/2026 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/1002844?ecd=bdc_podcast_libsyn_mscpedu

Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., explores the science and clinical evidence behind intermittent fasting and its role in promoting cardiometabolic health. He explains how aligning eating patterns with the body's natural circadian rhythms can improve weight, blood pressure, glucose regulation, and other risk factors, especially in individuals with metabolic syndrome or type 2 diabetes. Wilkinson highlights promising results from time-restricted eating studies conducted in collaboration with UC San Diego and the Salk Institute, where narrowing the daily eating window led to improved metabolic markers and potential benefits beyond weight loss. He also outlines practical tips for safely adopting this lifestyle approach and stresses the importance of ongoing research. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40319]

Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., explores the science and clinical evidence behind intermittent fasting and its role in promoting cardiometabolic health. He explains how aligning eating patterns with the body's natural circadian rhythms can improve weight, blood pressure, glucose regulation, and other risk factors, especially in individuals with metabolic syndrome or type 2 diabetes. Wilkinson highlights promising results from time-restricted eating studies conducted in collaboration with UC San Diego and the Salk Institute, where narrowing the daily eating window led to improved metabolic markers and potential benefits beyond weight loss. He also outlines practical tips for safely adopting this lifestyle approach and stresses the importance of ongoing research. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40319]

Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., explores the science and clinical evidence behind intermittent fasting and its role in promoting cardiometabolic health. He explains how aligning eating patterns with the body's natural circadian rhythms can improve weight, blood pressure, glucose regulation, and other risk factors, especially in individuals with metabolic syndrome or type 2 diabetes. Wilkinson highlights promising results from time-restricted eating studies conducted in collaboration with UC San Diego and the Salk Institute, where narrowing the daily eating window led to improved metabolic markers and potential benefits beyond weight loss. He also outlines practical tips for safely adopting this lifestyle approach and stresses the importance of ongoing research. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40319]

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/BPN865. CME/AAPA credit will be available until August 4, 2026.A New Era in GPP Treatment: Clinical Insights, Biomarkers, and Emerging Therapies In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an independent medical educational grant from Boehringer Ingelheim Pharmaceuticals, Inc.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/BPN865. CME/AAPA credit will be available until August 4, 2026.A New Era in GPP Treatment: Clinical Insights, Biomarkers, and Emerging Therapies In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an independent medical educational grant from Boehringer Ingelheim Pharmaceuticals, Inc.Disclosure information is available at the beginning of the video presentation.

In this episode, we explore how nonprofit organizations like LBDA are working alongside industry partners to shape the evolving landscape of dementia biomarkers—bridging scientific innovation with real-world care. Featuring an engaging conversation with Dr. Sudhir Sivakumaran, Dr. Kathleen Poston, and Dr. Dustin Dunham on clinical utility, patient-centered research, and the road to broader adoption of biomarkers in Lewy body dementia, Alzheimer's disease and related disorders. This episode is sponsored by GE HealthCare

In this episode, we take a critical look at the longevity movement and explore the most valuable—yet elusive—biomarkers for athletes. Learn more about your ad choices. Visit megaphone.fm/adchoices

Our kidneys filter out waste while retaining substances the body needs, such as electrolytes. Kidney health, which can be assessed with blood and urine biomarker tests, is paramount to overall health. Yet lifestyle, such as the Western diet and other factors, can damage the kidneys, leading to either a slow progression of issues or acute injury. Dr. Rick Johnson and Mike Haney discuss the role of the kidneys, what lifestyle factors affect kidney health, ways to support the kidneys, and what your biomarker results tell you about the function of these crucial organs.Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl

In this conversation, Thoryn Stephens, a leading expert in neurotechnology and the founder of Brain One, discusses the importance of brain fitness and cognitive training in the modern world. He emphasizes the need for platforms that help individuals optimize their brain health through micro habits and behavioral changes. The discussion covers various aspects of brain measurement, the impact of sleep and nutrition, and the challenges posed by digital distractions. Thorne also shares insights into the future of Brain One and its partnerships aimed at enhancing cognitive health.Chapters00:00 Introduction to Neurotechnology and Brain Fitness03:06 The Importance of Cognitive and Physical Training06:12 Brain Measurement and Optimization Techniques09:04 Adaptive Programs and Micro Habits for Brain Health12:02 The Role of Environment and Connection in Cognitive Health14:58 Changing Behavior and Biomarkers through Micro Habits18:02 The Silent Killers of Cognitive Health20:58 Top ROI Habits for Cognitive Longevity22:12 Optimizing Daily Routines for Better Health25:20 Understanding the Core Areas of Health27:43 Addressing Distraction and Digital Overload30:20 Integrating Technology and Holistic Health34:17 Future Innovations and Partnerships in Health

Standard blood tests barely scratch the surface. Ryan Smith shares how TruDiagnostic's TruAge & TruHealth tests use over 1,700 biomarkers from just a drop of blood to measure biological age, hormone health, immunity & more. Go beyond standard labs & start bioharmonizing with cutting-edge precision so you can make decisions that actually impact how you feel & age. Meet our guest Ryan Smith studied Biochemistry at Transylvania University before founding Tailor Made Compounding, which became one of the fastest-growing healthcare companies in the U.S. After exiting in 2020, he launched several ventures, including TruDiagnostic, a CLIA-certified lab specializing in methylation-based diagnostics for longevity & preventive health. TruDiagnostic leads the field with one of the largest private epigenetic databases, over 13,000 patients, & active participation in 30+ clinical research studies. Ryan remains a key figure in advancing functional medicine through innovative health data solutions. Thank you to our partners Outliyr Biohacker's Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways Biological age gives a clearer picture of health risk than birthdate by showing how your body is actually aging Lifestyle basics like exercise, clean eating, stress reduction & social connection remain top tools for aging well Some biological age tests are more reliable thanks to stronger prediction power & actionable results Longevity interventions can now be ranked using technology that tracks measurable improvements over time Leading tests don't just score your age but give clear next steps to improve healthspan & lifespan DNA methylation data offers biomarker proxies that sometimes outperform traditional blood tests Methylation-based tests bring better precision & consistency than standard lab results affected by daily shifts Immune system strength plays a major role in aging by influencing inflammation & clearing damaged cells Supplement & lifestyle tracking tools now show whether specific changes are actually improving key health markers TruAge tests work well for most while biohackers may benefit more from deeper panels like the TruHealth test Episode Highlights 3:29 What Biological Age Really Tells You 10:12 Inside TruDiagnostic's Testing Framework 11:39 Key Lifestyle & Supplement Insights from the Data 15:10 How to Interpret Your Report & Take Action 30:12 Understanding Your Immune & Metabolic Health 45:29 Practical Application & Future of Epigenetic Testing Links Watch it on YouTube: https://youtu.be/MykPl4fZ3Sc  Full episode show notes: outliyr.com/221 Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

The August 2025 recall spotlights four previously released episodes on topics related to dementia diagnosis. The episode begins with Dr. Amy Brodtmann discussing the complexities of diagnosing frontotemporal dementia in clinical practice. Next, Dr. Joseph Therriault delves into the use of plasma biomarkers in diagnosing Alzheimer disease. In the third episode, Dr. Trey Bateman discusses the growing significance of blood-based biomarkers in Alzheimer disease. The episode concludes with Dr. Gregg Day discussing the clinical implications of using plasma biomarkers in real-world patient care. Podcast links:  Frontotemporal Dementia Differential Diagnosis in Clinical Practice Diagnosis of Alzheimer Disease Using Plasma Biomarkers Understanding Blood-Based Biomarkers in Alzheimer Disease Diagnostic Performance of Plasma Biomarkers in the Outpatient Memory Clinic Article links:  Frontotemporal Dementia Differential Diagnosis in Clinical Practice Diagnosis of Alzheimer's Disease Using Plasma Biomarkers Adjusted to Clinical Probability Diagnostic Performance of Plasma p-tau217 and Aβ42/40 Biomarkers in the Outpatient Memory Clinic Disclosures can be found at Neurology.org. 

Many traditional doctors completely miss the connection between Lyme disease and your body's detoxification pathways and it's costing people decades of unnecessary suffering. After sitting down for 90 minutes with Dr. Christina Rahm, who beat Lyme at 19 using detox protocols, here's what blew my mind: Lyme isn't just about spiral bacteria hiding in your tissues. The solution isn't more antibiotics; it's supporting your body's natural ability to eliminate the cellular trash that's jamming up your biological machinery. Join the Ultimate Human VIP community and gain exclusive access to Gary Brecka's proven wellness protocols today!: https://bit.ly/4ai0Xwg Connect with Dr. Christina Rahm: Get Dr. Christina Rahm's book, “Cure the Causes: Live the Life You Want, Not the One Prescribed“ here: http://bit.ly/44HNz3E   Listen to "The Dr. Rahm Show" on all your favorite platforms! YouTube: http://bit.ly/4f6mhrg Spotify: http://bit.ly/44Kbqje Apple Podcasts: http://bit.ly/4nZnJQ9   Connect with Dr. Christina Rahm: Website: http://bit.ly/44WKxaB YouTube: http://bit.ly/4eW7eQA Instagram: http://bit.ly/46lLLOR TikTok: http://bit.ly/3UlNLPM Facebook: http://bit.ly/4kO1B8k X.com: http://bit.ly/4kLROQf LinkedIn: http://bit.ly/4kRxm0C Thank you to our partners: H2TABS - USE CODE “ULTIMATE10” FOR 10% OFF: https://bit.ly/4hMNdgg BODYHEALTH - USE CODE “ULTIMATE20” FOR 20% OFF: http://bit.ly/4e5IjsV BAJA GOLD - USE CODE "ULTIMATE10" FOR 10% OFF: https://bit.ly/3WSBqUa EIGHT SLEEP - SAVE $350 ON THE POD 4 ULTRA WITH CODE “GARY”: https://bit.ly/3WkLd6E COLD LIFE - THE ULTIMATE HUMAN PLUNGE: https://bit.ly/4eULUKp WHOOP - GET 1 FREE MONTH WHEN YOU JOIN!: https://bit.ly/3VQ0nzW MASA CHIPS - GET 20% OFF YOUR FIRST ORDER: https://bit.ly/40LVY4y VANDY - USE CODE “ULTIMATE20” FOR 20% OFF: https://bit.ly/49Qr7WE AION - USE CODE “ULTIMATE10” FOR 10% OFF: https://bit.ly/4h6KHAD A GAME - USE CODE “ULTIMATE15” FOR 15% OFF: http://bit.ly/4kek1ij HAPBEE - FEEL BETTER & PERFORM AT YOUR BEST: https://bit.ly/4a6glfo CARAWAY - USE CODE “ULTIMATE” FOR 10% OFF: https://bit.ly/3Q1VmkC HEALF - GET 10% OFF YOUR ORDER: https://bit.ly/41HJg6S BIOPTIMIZERS - USE CODE “ULTIMATE” FOR 10% OFF: https://bit.ly/4inFfd7 RHO NUTRITION - USE CODE “ULTIMATE15” FOR 15% OFF: https://bit.ly/44fFza0 GENETIC TEST: ⁠https://bit.ly/3Yg1Uk9 Watch  the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka: Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X.com: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG Timestamps: 00:00 Intro 02:38 Journey with Lyme Disease 07:42 What is Immuno Fatigue?  14:21 Overcoming Lyme Disease 23:58 Fungal and Bacterial Component from Lyme Disease 30:59 Self-Treatment from Lyme Disease 34:57 Zeolite Definition and Benefits 41:18 Types of Zeolite Products 46:12 Testing and Biomarkers for Metals, Lyme 57:54 P450 System Definition and Biomarkers 1:03:29 Starting a Detoxification Journey 1:10:00 Getting Emotional and Spiritual Toxins Out of Your Life 1:16:44 What is String Theory? 1:18:52 Treatment Regimens for Children 1:24:15 What does it mean to you to be an “Ultimate Human?” 1:25:00 Connect with Dr. Rahm The Ultimate Human with Gary Brecka Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The Content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions. Learn more about your ad choices. Visit megaphone.fm/adchoices