Podcasts about biomarkers

This week, we present an inspiring episode for anyone interested in the history, present, and future of prostate cancer care. In this Legends in Urology installment of the BackTable Urology Podcast, Dr. Gerald Andriole joins guest host Dr. Niraj Badhiwala to reflect on a career that has left a lasting impact on the field. --- SYNPOSIS Dr. Andriole shares personal stories from his upbringing in Northeastern Pennsylvania and his journey into medicine. He reflects on his expedited education through Penn State and Jefferson Medical College and his path to urology. He discusses his pivotal work in prostate cancer screening, including the influence of major trials like The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial, and traces the evolution of surgical and diagnostic techniques. The conversation also touches on current innovations and the future of prostate cancer management, offering valuable advice for the next generation of urologists. --- TIMESTAMPS 00:00 - Introduction01:59 - From Childhood to Medical School06:48 - Discovering Urology16:52 - Pioneering Prostate Cancer Screening24:07 - The PLCO Study: Design and Challenges28:57 - Controversies and Criticisms in Prostate Cancer Screening33:29 - Evolving Practices in Prostate Cancer Management44:19 - Future of Prostate Cancer Treatment

In this conversation, Dr. Jeffrey Gladden, a longevity doctor and author, shares his journey from traditional medicine to the field of longevity and health optimization. He discusses the importance of understanding thyroid function, mental well-being, and the personal meaning of longevity. Dr. Gladden outlines five key circles of longevity, emphasizes the role of biomarkers in assessing health, and shares daily habits that contribute to a youthful life. He also delves into testosterone optimization, innovative approaches to cardiovascular health, and the critical role of the nervous system in overall wellness. Finally, he highlights exciting future projects in the field of longevity medicine.Chapters00:00 Introduction to Longevity and Health02:11 Dr. Gladden's Personal Journey to Longevity08:41 Defining Longevity and Its Meaning11:58 The Five Circles of Longevity18:13 Biomarkers of Aging and Youthfulness24:19 The Importance of Enjoying Exercise28:19 Understanding VO2 Max and Cardio Training31:19 The Role of the Nervous System in Strength Training32:01 Testosterone Optimization and Its Challenges40:00 Innovations in Longevity and Health

Wellness + Wisdom | Episode 750 Does AI hold the key to fixing the modern healthcare system that's keeping us sick? Nathan Graville, CEO + Co-Founder of Geviti, joins Josh Trent on the Wellness + Wisdom Podcast, episode 750, to reveal why “feeling good” and “being healthy” are two very different things, how routine blood tests can expose hidden inflammation before it becomes disease, why reactive care driven by Big Pharma benefits from keeping you sick, and how AI doctors can help you reclaim ownership of your health. "Within the next 5 years, everybody is going to have an AI doctor in their pocket, and the whole traditional healthcare system is going to be reshaped forever. That's how we make longevity accessible to everybody, and it will be completely normal to live into our 120s, 130s, 140s." - Nathan Graville 20% Off Geviti Geviti offers cutting-edge health solutions tailored to various wellness needs, from longevity and hormone health to weight management and sexual vitality. Geviti's personalized approach includes regular consultations and follow-up tests, ensuring that each aspect of a customer's health regimen is optimized for their current state of health. Whether you're addressing specific health issues or aiming to enhance overall well-being, Geviti's comprehensive testing and personalized health plans provide the tools and support necessary for achieving optimal health. 20% OFF GEVITI Use code JOSH20 at checkout In This Episode, Nathan Graville Uncovers: [01:05] Feeling Good ≠ Healthy Nathan Graville Geviti Why feeling fine doesn't mean that we are healthy. How being fit doesn't equal being healthy. The importance of getting blood tested. Why doctors usually don't test C-reactive protein. [05:15] Proactive Health Care Why proactive care is the only way to achieve true health. How Big Pharma benefits from us being sick. What tools can help us measure our health. How preventative care has become more accessible in the past 10 years. [08:05] How to Optimize Your Health for Longevity Why longevity doctors are extremely expensive and hard to find. How AI makes longevity accessible to everybody. Why longevity shouldn't be obsessive. The role of mental health in our lifespan. How traditional healthcare is going to change with the rise of AI. [13:30] AI Bias: Can You Really Trust ChatGPT? How AI is evolving faster than we think. Why people assume that every output AI provides is accurate. How AI gives us very convincing responses to things we don't know anything about. Why the right prompting creates more valid results. The longer we collect our data with Geviti, the better data it gives us about our health. [19:05] From Grief to Helping Others Why Nathan believes his father still exists in a different form after passing. How Geviti could have saved his father. Why the pandemic made it difficult to get proper care. How Nathan created Geviti to honor his father. Why Nathan changed his opinion on psychotherapy. How therapy helped him heal through being vulnerable. [28:10] Modern Health Care Is A Profit-Making Machine Why the medical system is good at fixing injuries. How reactive care is highly profitable, and there's an incentive to keep people sick. Why Make America Healthy Again draws attention to the problems of the healthcare system. How we shouldn't expect our doctors to own our health. Why we need to take down Big Pharma. How Geviti is not profit first, but people first. [34:45] Are You Living to Work? Conscious Capitalism by John Mackey + Raj Sisodia How our bodies respond to nervous system dysregulation. Why we are misaligned in our priorities, and we live to work. How Nathan puts God first, family second, and work third. [39:10] Biological Age Testing How Josh discovered that his biological age was much younger than his chronological age. Why getting blood work is the first step, then we need to take action. How Geviti provides practical tools and a team to support your journey. Why assessing biological age has changed and there are several different methods. How biological age testing shows how we're improving our longevity. Why basic lifestyle changes can decrease our biological age. [46:35] Methylation + Supplementation 734 Kirk Parsley MD | Sleep As Medicine: How To Sleep Like Royalty + Stop Being Sick How Geviti ensures the accuracy of their lab tests. What labs they're working with for diagnostic solutions. 694 Shawn Wells | Your Ultimate Guide To Healing Mental + Physical Health How 30-40% of people struggle with methylation. Why many supplements are not bioavailable and don't absorb into the body. How supplements are meant to be used for the best effect. Why supplementation must be data driven. [54:55] Can You Rely on Technology with Your Health? NOOTOPIA (10% off with code JOSH10) How older generations don't trust technology as much as younger people. Why we can't hear what our body's telling us it needs. How Geviti protects their clients' data. Why technology is a part of human evolution. How using technology doesn't mean we're going against nature. [01:00:45] Peptides: Nature's Miracle? Peptides already exist in our bodies and are completely natural. How peptides bind to the receptors of our cells and support healing. Why peptides are a threat to Big Pharma. How exogenous growth hormones can cause serious health issues. Why we should only buy peptides from pharmacies. How research chemical companies produce peptides that can be very harmful. [01:09:15] The Future of Health Why Eli Lilly is going against compounding pharmacies. We need more compounding pharmacies in order to make health products more accessible. How we can decentralize health information. Why we could invent cures to all diseases if we established a decentralized database. How human nature might stop us from creating a new system. [01:16:20] Trust Your Intuition Why everyone has access to intuition. How our intuition gets clouded. Why people fall for snake oil supplements. How we can judge a company by their founder. Why we always have a gut feeling at the beginning that tells us the truth. How some supplements work for some people but don't work for others. Why companies don't need to rely on third-party studies anymore. [01:25:00] Geviti Can Save Your Life + Time How Geviti has helped people diagnose cancer and cardiovascular disease. Why Geviti saves us time compared to going to a doctor's office. The importance of designing products around mothers and busy entrepreneurs. [01:29:00] AI for Longevity Why in the future most people will live to be over 100. How AI will create abundance and make services more accessible. Why Geviti's costs have gone down since the rise of AI. [01:33:50] Heal Your Body with Stem Cells Why stem cell treatments are becoming more popular. Joy Kong MD How Geviti is developing a stem cell product from umbilical cords. Why MSC stem cells target what needs to be healed. How one stem cell IV saved a man's life whose liver was failing. Why peptides and stem cells are going to help us live longer. Leave Wellness + Wisdom a Review on Apple Podcasts Power Quotes From The Show Big Pharma Wants You Sick! "There's incentive to keep people sick because Big Pharmaceutical will profit off of it, and then they'll prescribe the medications and the medications to combat the side effects of their own medications. It's a vicious cycle that's very hard to escape." - Nathan Graville Peptides + MSCs "Peptides and MSCs are the future of longevity. These are two therapeutics that will get us to living into our hundreds. When you do a MSC IV, it's going to find out where in your body you need healing and it's going to go to those areas on its own. This is potentially the most powerful therapeutic that we know about in existence as it relates to longevity." - Nathan Graville Feeling Healthy Doesn't Equal Being Healthy "There's no way to know if you're healthy based on just how you feel. You can have elevated markers that are directly correlated to all-cause mortality. Which is why looking underneath the hood is so crucially important. The only way to know is by doing a routine blood work." - Nathan Graville Links From Today's Show  Nathan Graville Geviti Conscious Capitalism by John Mackey + Raj Sisodia 734 Kirk Parsley MD | Sleep As Medicine: How To Sleep Like Royalty + Stop Being Sick 694 Shawn Wells | Your Ultimate Guide To Healing Mental + Physical Health NOOTOPIA (10% off with code JOSH10) Joy Kong MD   Josh's Trusted Products | Up To 40% Off Shop All Products Biohacking⁠ MANNA Vitality - Save 20% with code JOSH20 HigherDOSE - 15% off with the code WELLNESSANDWISDOM PLUNGE - $150 off with discount code WELLNESSFORCE Pulsetto - Save 20% with code "JOSH" SaunaSpace - 10% off with discount code JOSH10 Ultrahuman Ring Air - 10% off with code JOSH NutriSense - 30% off with WELLNESSFORCE Wellness Test Kits Choose Joi - Save 50% on all Lab Tests with JOSH Blokes - Save 50% on all Lab Tests with JOSH FertilityWize Test by Clockwize - Save 10% with code JOSH Tiny Health Gut Tests - $20 off with discount code JOSH20 VIVOO Health Tests - Save 30% off with code JOSH SiPhox Health Blood Test - Save 15% off with code JOSH Nutrition + Gut Health Organifi - 20% off with discount code WELLNESSFORCE SEED Synbiotic - 25% off with the code 25JOSHTRENT Paleovalley -  Save 15% off here! EQUIP Foods - 20% off with the code WELLNESS20 DRY FARM WINES - Get an extra bottle of Pure Natural Wine with your order for just 1¢ Just Thrive - 20% off with the code JOSH Legacy Cacao - Save 10% with JOSH when you order by the pound! Kreatures of Habit - Save 20% with WISDOM20 Force of Nature Meats - Save 10% with JOSH Supplements MANNA GOLD - $20 off with code JOSHGOLD Adapt Naturals - 20% off with discount code WELLNESSFORCE MitoZen - 10% off with code WELLNESSFORCE Activation Products - 20% off with code JOSH20 BiOptimizers - 10% off with discount code JOSH10 Fatty15 Essential Fatty Acids Supplement - Get 15% off with code JOSH15 Sleep BiOptimizers Sleep Breakthrough - 10% off with JOSH10 Zyppah Anti-Snoring Mouthpiece - 20% off with the code JOSH MitoZen Super SandMan Ultra™ (Melatonin Liposomal)+ 10% off with WELLNESSFORCE Luminette Light Therapy Glasses - 15% off with JOSH Cured Nutrition CBN Night Oil - 20% off with JOSH Natural Energy MTE - Save 20% with JOSH TruKava - Save 20% with code JOSH20 Drink Update - Save 25% with discount code JOSH25 Lifeboost Coffee - Save 10% with JOSH10 EONS Mushroom Coffee - 20% off with the discount code JOSH20 EnergyBITS - 20% off with the code WELLNESSFORCE BUBS Naturals - Save 20% with JOSH20 Fitness + Physical Health Detox Dudes Online Courses - Up to $500 off with discount code JOSH Kineon - 10% off with discount code JOSH10 Create Wellness Creatine Gummies - 20% off with discount code JOSH BioPro+ by BioProtein Technology - Save $30 OFF WITH CODE JOSH Drink LMNT - Zero Sugar Hydration: Get your free LMNT Sample Pack, with any purchase ⁠Myoxcience - 20% off with the code JOSH20 Healthy Home SunHome Saunas - Save $200 with JOSH200 JASPR Air Purifier - Save 10% with code WELLNESS QI-Shield EMF Device by NOA AON - 20% off with the code JOSH Holy Hydrogen - $100 off with discount code JOSH SimplyO3 - 10% off with discount code JOSH10 LEELA Quantum Upgrade + Frequency Bundles - Get 15 days free with code JOSH15 TrulyFree Toxic- Free Cleaning Products - Get 40% off + Freebies with code WELLNESSFORCE Mental Health + Stress Release Mendi.io - 20% off with the code JOSH20 Cured Nutrition CBD - 20% off with the discount code JOSH NOOTOPIA - 10% off with the discount code JOSH10 CalmiGo - $30 off the device with discount code JOSH30 QUALIA - 15% off with WELLNESSFORCE LiftMode - 10% off with JOSH10 Personal Care⁠ The Wellness Company's Emergency Health Kits + More - Save 10% with code JOSH Canopy Filtered Showerhead + Essential Oils - Save 15% with JOSH15 Farrow Life - Save 20% with JOSH Timeline Nutrition - 10% off with JOSH ⁠⁠Intelligence of Nature - 15% off Skin Support with the code JOSH15⁠⁠ Young Goose - Save 10% with code JOSH10 Mindfulness + Meditation BREATHE - 33% off with the code PODCAST33 Neuvana - 15% off with the code WELLNESSFORCE Essential Oil Wizardry - 10% off with the code WELLNESSFORCE Four Visions - Save 15% with code JOSH15 Lotuswei - 10% off with JOSH Clothing NativeToWear - Save 20% with code JOSH20 Rhizal Grounded Barefoot Shoes - Save 10% with code WELLNESS Earth Runners Shoes - 10% off with the code JOSHT10 MYNDOVR - 20% off with JOSH Free Resources M21 Wellness Guide - Free 3-Week Breathwork Program with Josh Trent Join The Liberated Life Tribe About Nathan Graville Nathan Graville is a tech founder with a passion for designing beautiful products that deliver meaningful value. His commitment to building technology for positive impact is currently centered on increasing both healthspan and lifespan. He designs and builds products to enhance user experiences and improve lives, and is fueled by the desire to challenge the status quo and deliver meaningful change to the world. Nathan is driven by the prospect of bringing impactful projects to life and aims to create positive change on a global scale. Website Instagram Facebook YouTube

Inflammation has become a nutrition buzzword, often used in extreme or misleading ways. This episode aims to clarify what inflammation is, how it relates to diet and health, and whether specific foods truly provoke inflammatory responses in the body. The episode provides a nuanced, evidence-based look at inflammation and diet. It explains the difference between acute and chronic inflammation, outlines the role of chronic low-grade inflammation in disease, and emphasizes that overall dietary patterns – rather than any single food – are what influence our inflammatory status. Commonly demonized foods (such as sugar, wheat, and dairy) are scrutinized, and the conversation debunks myths about them being uniformly “inflammatory.” In this episode, Danny takes a look at what the scientific evidence actually shows about anti-inflammatory diets. Note: This is a Premium-exclusive episode. Timestamps 01:06 Understanding Inflammation: Basics and Biomarkers 04:02 Acute vs. Chronic Inflammation 14:21 Biomarkers of Inflammation 22:51 Dietary Patterns and Inflammation 34:53 Specific Foods and Nutrients Impacting Inflammation 47:01 Practical Takeaways for an Anti-Inflammatory Diet 51:30 Conclusion Related Resources Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Related podcast episodes: 329: Diet & Inflammation 353: James Hébert, ScD – Dietary Inflammatory Index Sigma Statement: Nutrition & Immune Function The Dietary Inflammatory Index (DII) – Hébert et al., 2019

Synopsis: What happens when a world-class scientist and a philanthropic legacy collide with one of medicine's greatest challenges? Dr. Howard Fillit and Mark Roithmayr of the Alzheimer's Drug Discovery Foundation (ADDF) join host Alok Tayi for an inspiring conversation on bold science, visionary funding models, and the future of Alzheimer's research. From treating Estée Lauder in the 1990s to building a $100M venture philanthropy engine, they trace ADDF's evolution into a global leader in high-risk, high-reward drug development. The discussion covers the rise of biomarkers and digital diagnostics, the foundation's partnerships with visionaries like Bill Gates and Jeff Bezos, and how ADDF's venture philanthropy approach bridges the “valley of death” in biotech. They also dive into global regulatory challenges, the economic urgency of Alzheimer's, and why the future lies in prevention, precision medicine, and a patient-first mindset. This episode is a masterclass in scientific grit, ecosystem thinking, and turning urgency into progress. Biography: Howard Fillit, MD Founding Executive Director and Chief Science Officer of the Alzheimer's Drug Discovery Foundation Howard Fillit, MD, is a geriatrician, neuroscientist, and innovative philanthropy executive, who has led the Alzheimer's Drug Discovery Foundation (ADDF) since its founding. Dr. Fillit has held faculty positions at The Rockefeller University, the SUNY-Stony Brook School of Medicine and the Cornell University School of Medicine. In 1987, he joined the Mount Sinai School of Medicine, where he is a clinical professor of geriatric medicine and palliative care, medicine and neuroscience. Dr. Fillit also maintains a limited private practice in consultative geriatric medicine with a focus on Alzheimer's disease and related dementias. He has authored or co-authored more than 300 publications and is the senior editor of Brocklehurst's Textbook of Geriatric Medicine and Gerontology. Dr. Fillit is the recipient of many awards and honors including the Rita Hayworth Award from the Alzheimer's Association. Mark Roithmayr Chief Executive Officer Mark Roithmayr is an admired nonprofit leader with four decades of experience in both start-ups and mature organizations. As CEO of the ADDF, he is responsible for steering the Foundation's overall strategy, focus, and business operations. Since joining the ADDF in 2017, the organization has transformed dramatically in impact, scale, presence, and brand. Under his leadership, the ADDF's revenue has increased five-fold from $17M to over $90M, and mission-related investing has grown over 100%. He works closely with Dr. Fillit, executive leadership, and the board to advance the ADDF's mission of accelerating the discovery of drugs to prevent, treat, and cure Alzheimer's disease and related dementias. His key accomplishments include securing donations from Bill Gates, Jeff Bezos, and MacKenzie Scott, and a 10-figure gift from the Lauder family to cover ADDF's overhead for the next 20 years.

Have you heard of longevity medicine? It's next-level healthcare—and Dr. Darshan Shah is one of the pioneers leading the way. In this episode, Dr. Shah shares how he's transforming the way we treat women in perimenopause and postmenopause by focusing on real root causes—not just symptom management.  We cover: What he learned about women's health as a surgeon How he approaches menopause differently than most doctors The truth about hormone testing during the transition The real drivers of Alzheimer's, osteoporosis, and heart disease in women Why so many doctors are confused about menopause care Exactly how to empower yourself at your first menopause visit How he uses the Wellness Wheel to individualize care A peek into cutting-edge therapies like Therapeutic Plasma Exchange and NAD+   Darshan Shah, MD, is a health and wellness specialist, board-certified surgeon, published author, entrepreneur, and founder of Next Health, the first, largest and fastest-growing health optimization and longevity clinic. He began his career at an accelerated MD program and earned his medical degree at the age of 21, becoming one of the youngest doctors in the United States. He then continued his training at the Mayo Clinic, and earned his MBA from Harvard Business School in 2015. As a longevity medicine specialist, he has advised thousands of patients on how to optimize their well-being and extend their healthspan and lifespan.    PREVIOUS EPISODE: https://www.drshah.com/extend-podcasts/zora-benhamou Extend Podcast: https://podcasts.apple.com/us/podcast/welcome-to-extend-with-darshan-shah-md/id1773578243?i=1000673875409  Biomarkers list: https://www.drshah.com/biomarkers   Contact Dr. Darshan Shah Website: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd  Email: contact@drshah.com   Give thanks to our sponsors: Qualia senolytics and brain supplements. 15% off with code ZORA here. Try Vitali skincare. 20% off with code ZORA here https://vitaliskincare.com Get Primeadine spermidine by Oxford Healthspan. 15% discount with code ZORA ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Get Mitopure Urolithin A by Timeline. 10% discount with code ZORA at https://timeline.com/zora Try Suji to improve muscle 10% off with code ZORA at TrySuji.com https://trysuji.com Get Magnesium Breakthrough by Bioptimizers. 10% discount with code HACKMYAGE at https://bioptimizers.com/hackmyage Try OneSkin skincare with code ZORA for 15% off https://shareasale.com/r.cfm?b=2685556&u=4476154&m=102446&urllink=&afftrack= Join ⁠⁠⁠Biohacking Menopause⁠⁠⁠ before July 1, 2025 to win free Vitali Skincare! 20% off with code ZORA at VitaliSkincare.com   Join the Hack My Age community on: Facebook Page: ⁠⁠⁠⁠⁠@⁠Hack My Age⁠     Facebook Group: ⁠⁠⁠⁠⁠⁠@⁠Biohacking Menopause⁠⁠⁠⁠⁠⁠ ⁠  Private Women's Only Support Group: https://hackmyage.com/biohacking-menopause-membership/ Instagram: ⁠⁠⁠⁠⁠@⁠HackMyAge⁠    Website: ⁠⁠⁠⁠⁠⁠HackMyAge.com⁠     

Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]

Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]

Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]

Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]

Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]

Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]

Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]

In this episode, Dr Vignesh Devraj explores the profound Ayurvedic definition of health from the Sushruta Samhita and offers a fascinating correlation between these ancient principles and modern physiological biomarkers. Through a line-by-line breakdown of the classic Ayurvedic sutra, he explains how true health transcends physical fitness and encompasses harmony at the levels of body, mind, and spirit, providing a deep yet accessible exploration of what it truly means to be healthy, from both traditional and scientific perspectives. Episode Highlights:The Sanskrit meaning and layers of the Ayurvedic definition of healthWhy happiness is not the result of health, but a component of itHow to assess Vata, Pitta, and Kapha through BiomarkersUnderstanding Samadhatu and why it mattersAgni, metabolism, and weight managementMind-body harmony for lasting health Timestamps:00:00 - 02:00: Definition of health in Sushruta Samhita02:00 - 03:00: Health and Happiness03:00 - 07:30: Biomarkers that signal Dosha Imbalance07:30 - 10:00: Understanding Samadhatu10:00 - 12:30: Weight Loss, Fertility, and Overall Health12:30 - 15:24: Sleep, Stress, and EnduranceIf you are interested in doing one on one Ayurvedic consultation with Dr Vignesh Devraj, please find the details in this link: https://calendly.com/drvignesh/30-minute-session-with-dr-vignesh-devraj-md-ay-istIf you are economically challenged, please use the form provided to request a free Ayurvedic consultation here. (or copy paste this in your browser: https://docs.google.com/forms/d/e/1FAIpQLSd29nHcrC1RssR-6WAqWCWQWKKJo7nGcEm8ITEl2-ErcnfVEg/viewform )BALANCE THE MIGHTY VATA - ONLINE COURSE NOW AVAILABLE What makes Ayurveda unique in its treatment approach is its practical wisdom on the concept of Vata. Vata is responsible for Prana - the life energy, nervous system - the master panel of our body, and our emotions. In Ayurveda, it is mentioned that controlling Vata is the most difficult part of healing and recovery. Recently, I have recorded a workshop on - Balancing The Mighty Vata which has over 6 hrs of content, with notes filled with practical inputs that can be integrated into our life. You can access this at https://drvignesh.teachable.com/For further information about Dr Vignesh Devraj, kindly visit www.vigneshdevraj.com and www.sitaramretreat.com Instagram - @sitarambeachretreat | @vigneshdevrajTwitter - @VigneshDevrajWe truly hope you are enjoying our content. Want to help us shape and grow this show faster? Leave your review and subscribe to the podcast, so you'll never miss out on any new episodes. Thanks for your support.Disclaimer: - The content of the podcast episodes is not intended to be a substitute for professional medical procedures, consultations, diagnosis, or treatment in any manner. We strongly do not recommend using the content of these episodes as medical advice for any medical conditions for you, others, or for treating your patients

AGNTCY - Unlock agents at scale with an open Internet of Agents. Visit https://agntcy.org/ and add your support. What if your blood could reveal the future of your health - years before symptoms ever appear? In this episode of Eye on AI, Craig Smith sits down with Ash Anwar, co-founder of Molecular You, to explore how AI and advanced biomarker analysis are transforming how we detect and prevent disease.  From a real-life case where stage 1 pancreatic cancer was caught early, to the science behind tracking 250+ dynamic biomarkers, Ash breaks down how Molecular You is shifting healthcare from reactive treatment to proactive longevity.  They dive into the limitations of genetic testing, the power of machine learning models trained on clinical data, and how personalized action plans are helping individuals take control of their health in real time.  If you're curious about the intersection of AI, diagnostics, and the future of preventive medicine—this is a conversation you won't want to miss. Stay Updated: Craig Smith on X: https://x.com/craigss Eye on A.I. on X: https://x.com/EyeOn_AI (00:00) How AI Can Predict Disease Before It Happens   (02:02) Meet Ash Anwar: From Scientist to Health Tech Leader   (06:31) What Is Molecular You and How It Works   (09:43) Why Biomarker Tracking Over Time Is a Game-Changer   (15:46) How Molecular You Detected Stage 1 Pancreatic Cancer   (23:15) Biomarkers vs Genetics: What Really Matters   (28:11) The AI Models Behind Early Disease Detection   (32:37) How the Product Works for Clinics and Consumers   (35:05) Who They Compete With and What Makes Them Different   (37:34) Research vs Product: The Cancer Risk Challenge   (43:43) How Often Should You Get Tested?

Will an FDA cleared blood test for Alzheimer's disease ease or complicate diagnosis? Clearly in approving the test the FDA hopes for the former, yet the complete picture is more complex than that, says Abhay Moghekar, a blood biomarkers expert … Biomarkers alone don't mean Alzheimer's disease is present, Elizabeth Tracey reports Read More »

In this podcast, host Dr Amanda Heslegrave explores the rapidly evolving field of blood-based biomarkers in dementia research. These biomarkers offer exciting potential for quicker, more accessible dementia diagnosis, raising crucial questions about clinical readiness and implementation. -- Amanda is joined by two expert guests: Dr Jay Amin, University of Southampton – A clinician specialising in dementia, researching inflammation and immune biomarkers, particularly focused on diagnostics and prognosis. Dr Mark Roskey, Quanterix – Senior VP involved in developing ultra-sensitive biomarker detection technologies crucial for dementia research. Together, they discuss current developments, practical hurdles, ethical considerations, and future prospects of blood-based biomarkers, sharing perspectives from clinical, research, and industry viewpoints. -- Topics Covered:

Are you trying hard to do everything “right” with your health, eating clean, training hard, prioritizing sleep, but still feeling off? Frustrated with lack of attention to your lab work or feeling lost, not knowing what biomarkers to consider?If you're a wellness-minded active woman, especially a runner or endurance athlete age 35 and beyond, the truth is your lab work is telling you a story, EVEN when in range or borderline low/high. Ready to finally understand nuances, specific to your unique body? In this episode, Louise, one of the world's leading health, fitness, and performance experts, unpacks the biomarkers that can reveal what's really going on beneath the surface: hormonal shifts, under-fueling, inflammation, thyroid issues, under recovery, exercising incorrectly, cholesterol concerns, blood sugar imbalances, and more!You'll learn why standard medical labs often miss critical context for athletic women in perimenopause and beyond, and how to advocate for deeper, more relevant testing with your provider team. Additionally, variances in functional medicine, integrative health, and allopathic medicine are discussed. From interpreting ferritin levels like an athlete to spotting inflammation caused by overtraining, you'll walk away with real, actionable tools to take charge of your health.This isn't just about getting labs done. It's about getting answers that matter and support that makes a difference. Your performance, energy, and vitality depend on it. You absolutely deserve the knowledge, tools, and context to thrive DESPITE changing hormones, so let's learn, laugh, and level up together!Link to check out our free nutrition guide and join other fierce lady runners taking charge of their holistic health and fitness in our multi award-winning Badass Breakthrough 1:1 Academy to thrive through perimenopause with less stress: https://www.breakingthroughwellness.com/ Our affiliate link to check Function Health for comprehensive blood work: https://my.functionhealth.com/signup?code=LVALENTINE11&_saasquatch=LVALENTINE11  Take advantage of our podcast listener discount and save 20% off all of Kion's science-backed clean products: https://www.getkion.com/pages/maximizing Episode Highlights:(0:00) Intro(4:42) How to speak your doctor's language(6:42) Lab testing without breaking the bank(9:15) Why A1C is a hidden red flag(10:57) Ferritin and the endurance athlete(12:28) Infusions vs. real root cause healing(14:18) Inflammation markers and overtraining(16:33) Amino acid profile: The gut and protein story(18:19) 6-month progress: Biomarkers can change(22:36) Thyroid testing beyond TSH(25:21) Liver stress and what it reveals(28:03) BUN, creatinine, and hydration(34:05) Improving iron levels with whole foods(37:22) Comparing traditional vs. integrative ranges(38:57) Where to get more comprehensive testing(42:31) OutroTune in weekly to "Maximizing Fitness, Physique, and Running Through Perimenopause" for a simple female-specific science-based revolution. Let's unlock our best with less stress!I'd love to connect!Instagram

This week on Health Matters we reflect on the top health tips and  takeaways from our May series dedicated to Women's Health Month. Courtney is joined by Angelique Serrano to talk more about how to care for our skin, bone, and brain health, as well as ways to recognize and manage perimenopause symptoms. In their conversations with Health Matters, neurologist Dr. Sonja Blum and dermatologist Dr. Shari Lipner shared small daily habits that can make big contributions to long term health. Dr. Mary Rosser, an OB-GYN, shares a process for tackling sleep issues during perimenopause. Physiatrist Dr. Erica Eldon explains the importance of bone strength and how to prevent ailments like a broken hip. Courtney and Angelique share how the advice from NewYork-Presbyterian doctors opens space for women to discuss health care decisions in ways that are often overlooked and how they are inspired to prioritize their own health.___Health Matters shares stories of science, care, and wellness from NewYork-Presbyterian, one of the nation's most comprehensive healthcare systems.NewYork-Presbyterian's Health Matters features the latest news and insights from our world-class physicians, nurses, and experts; inspiring first-hand accounts from patients and caregivers; and updates on the latest research and innovations in patient care, all in collaboration with our academic partners Columbia and Weill Cornell Medicine.To learn more visit: https://healthmatters.nyp.org/ 

Living a Nutritious Life PodcastIn this episode of Living a Nutritious Life podcast, we're thrilled to welcome Dr. Darshan Shah, a pioneering physician and longevity expert.About Our Guest: Darshan Shah, MD, is a health and wellness specialist, board-certified surgeon, published author, entrepreneur, and founder of Next Health, the world's first and largest Health Optimization and Longevity clinic. He has advised thousands of patients on how to optimize their well-being and extend their healthspan and lifespan. Full bio here.What You'll Learn in This Episode:- The incredible story of Dr. Shah's transformation from an overworked, unhealthy surgeon to a thriving wellness entrepreneur.- The most powerful (and practical!) longevity technologies and tools, from peptides and plasma exchange to learning the advanced biomarkers to stay on top of.- Why relying on medication alone can be a slippery slope, and how lifestyle changes truly move the needle in prevention.- Actionable strategies you can implement—even at home—to take charge of your own health and longevity.Episode Highlights:- Dr. Shah's personal wake-up call: 10 medications at age 41- The truth about traditional medicine vs. “the science of health”- Inside Next Health: A unified model blending lifestyle, prevention, functional, and longevity medicine- Plasma exchange, peptides, and other leading-edge therapies for healthspan - The essential biomarkers you should be tracking- How to use GLP-1 agonists (and all peptides) safely and responsiblyAbout Living a Nutritious Life Podcast: Welcome to the Living a Nutritious Life podcast with Keri Glassman, MS, RDN, CDN, where we break down the latest nutrition science into smart, actionable tips to help you live your most nutritious life.On the Living a Nutritious Life podcast, Keri and her world-renowned guests cut through the noise, sharing unparalleled, forward-thinking tips, tricks, and the latest in health, wellness, and nutrition science.Based on Keri's whole-person approach to healthy living, each impactful episode extends far beyond the simplistic “get more sleep” and “eat your greens” advice. She connects the dots like no one else – like how morning yoga can make it easier to choose a healthy lunch, leading to better sleep at night.Listen as Keri and her expert guests explore the physiological and behavioral connections that explain, for example, why the common wisdom around dieting and exercising alone doesn't work, so you can finally make the meaningful changes you've been looking for.If you found value in this episode, please RATE, REVIEW and SHARE.Join our amazing global community of like-minded students and alumni. Get in on the action—enroll in our Become a Nutrition Coach program at nutritiouslife.com/bnc. Keri has a lot to teach, and we're here to help you get started on your journey!Connect with Dr. ShahFree Biomarker Guide https://www.drshah.com/biomarkersWebsite: https://www.drshah.com/Connect with Keri on social: Instagram: https://www.instagram.com/nutritiouslifeofficial/ Facebook: https://www.facebook.com/KeriGlassmanNutritiousLife Twitter: https://twitter.com/NutritiousLife_ LinkedIn: https://www.linkedin.com/company/nutritiouslife Pinterest: https://www.pinterest.com/nutritious_life/ Website: https://nutritiouslife.com/ Become a Nutrition Coach: https://nutritiouslife.com/bnc/Copyright © 2023-2025 Nutritious Life.#LivingaNutritiousLife #NutritiousLife Hosted on Acast. See acast.com/privacy for more information.

What happens when cutting-edge science meets compassion? In this episode of Sounds of Science, host Mary Parker sits down with two pioneers reshaping the future of research: Elizabeth Nunamaker, Executive Director of Global Animal Welfare and Training at Charles River, and Dr. Megan LaFollette, Executive Director of the 3Rs Collaborative. From digital biomarkers to environmental health monitoring, they reveal how innovation and collaboration are redefining what's possible in animal welfare — and raising the bar for ethical, high-quality research. Tune in to explore the tools, strategies, and bold ideas driving meaningful change across the scientific community.Show NotesAdvancing Alternatives | Charles RiverEvolving Animal Welfare: Science, Ethics, and Innovation | Sounds of Science Can You Practice High-quality Science and 3Rs? | Eureka BlogAnimals in Research | Charles RiverResearch Models & Services | Charles River

Big shift in Alzheimer's care! We can now predict it years in advance using

This week please join author Brian Lindman and Executive Editor and Editorialist James de Lemos as they discuss the article "Cardiac Biomarkers in Patients With Asymptomatic Severe Aortic Stenosis: Analysis From the EARLY TAVR Trial" and the accompanying editorial "Biomarkers to Guide the Timing of Aortic Valve Replacement in Asymptomatic Aortic Stenosis: Where Do We Stand After Early TAVR?" For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20250529.497472

David McDermott joins us on the heels of his outstanding discussion of the clinical science symposium on RCC biomarkers.

Levels offers biomarker testing to give you more insight into your health status so you can understand the root causes of your symptoms, take a preventive approach to disease, and see if your lifestyle changes or other interventions are reducing your risk factors and improving your health. Dr. Anjali Dsouza and Mike Haney discuss why biomarker testing can be beneficial, how to understand your levels, factors that affect your levels, and which biomarkers are no-brainers to get tested.Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠⁠⁠⁠⁠⁠⁠https://levels.link/wnl⁠⁠⁠⁠⁠⁠Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

This is the latest episode of the free DDW narrated podcast, titled “Innovative uses for biomarkers in drug discovery”, which covers two articles written for DDW Volume 24 – Issue 4, Fall 2023. They are called: “How biomarkers can help discover new treatments for women's health” and “Could NfL accelerate drug development for neurodegenerative diseases?” In the first article, DDW Editor Reece Armstrong speaks to Dr Steve Gardner, Co-Founder and CEO of PrecisionLife about work the company is doing to improve our understanding of endometriosis. In the second article, Professor Andy Whiting and Dr Tony Lockett discuss how specific levels of a protein could be used to advance drug development in neurodegenerative diseases.

This week on Health Matters, Courtney Allison is joined by Dr. Sonja Blum, a neurologist with NewYork-Presbyterian and Weill Cornell Medicine.Dr. Blum shares simple ways to protect your brain health as you age.They explore the science behind nutrition and exercise in relation to the brain, as well as the  importance of social engagement, mental health, and quality sleep. They also speak about evidence that shows how meditation benefits the brain. Plus, they touch on whether or not brain puzzles actually help with cognitive function, and the unique brain health challenges faced by women.___Dr. Sonja Blum, M.D., Ph.D. is an Associate Professor of Clinical Neurology at Weill Cornell Medicine and Associate Attending at NewYork-Presbyterian/Weill Cornell Medical Center, and the Director of Memory Disorders and Cognitive Neurology Division at NewYork-Presbyterian and Weill Cornell Medicine. Dr. Blum sees adults of all ages who are having memory, attention, language, and other cognitive concerns, or who have a family history of dementia and concerned about their risks. Dr. Blum also has expertise in traumatic brain injury (TBI), including recovery from disorders of consciousness (DOC) and the long-term effects of moderate to severe TBI, as well as concussions. Her research focuses on mechanisms of cognitive aging and long-term memory dysfunction, and traumatic brain injury. Dr. Blum trained as a physician scientist completing the MD/PhD program at the University of Texas McGovern Medical School in Houston. She completed her neurology residency and behavioral neurology fellowship at the Columbia University Neurological Institute in New York City.___Health Matters is your weekly dose of health and wellness information, from the leading experts. Join host Courtney Allison to get news you can use in your own life. New episodes drop each Wednesday.If you are looking for practical health tips and trustworthy information from world-class doctors and medical experts you will enjoy listening to Health Matters. Health Matters was created to share stories of science, care, and wellness that are happening every day at NewYork-Presbyterian, one of the nation's most comprehensive, integrated academic healthcare systems. In keeping with NewYork-Presbyterian's long legacy of medical breakthroughs and innovation, Health Matters features the latest news, insights, and health tips from our trusted experts; inspiring first-hand accounts from patients and caregivers; and updates on the latest research and innovations in patient care, all in collaboration with our renowned medical schools, Columbia and Weill Cornell Medicine. To learn more visit: https://healthmatters.nyp.org

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Systolic and Diastolic Blood Pressure, Cardiac Biomarkers, and Cardiovascular Mortality in Adults Without Cardiovascular Disease.

With more than two decades of experience at the intersection of biostatistics and biomedical imaging, Bracken Senior Partner Dr. David Raunig has been a driving force in biomarker development, validation, and regulatory strategy. From leading FDA biomarker qualification review teams to co-inventing imaging advancements and setting industry-wide standards through QIBA, David has played a pivotal role in defining how we measure—and trust—biological data in clinical trials.In this episode of Fractals: Life Science Conversations, David and host Colin Miller explore:What truly defines a biomarker—and how clinical outcome assessments differ from biological markers.Why the FDA's "context of use" is key to biomarker qualification and how to demonstrate that a biomarker measures what it's meant to.How the evolution of imaging—from WHO criteria to RECIST to AI-assisted reads—could transform how we assess tumor burden and therapeutic response.Statistical strategies for trial design and endpoint validation, and why QIBA's standardized imaging protocols are essential tools for trial sponsors.Tune in to Fractals on your favorite podcast platform, and connect with Bracken to learn how David and our experts can support your clinical trial strategy from biomarker planning to regulatory approval.

In this episode, we talk with Dr. Chris Davlantes about the evolution of blood tests to detect and risk stratify traumatic brain injuries. Over the last few years, we have seen tests emerge, but now have access to POC technology that may assist emergency physicians and others to get patients the care they need and avoid unnecessary imaging if possible. This episode was supported by Abbott Point of Care.

After tons of messages, I'm breaking down our detox journey—why we're doing it, what we tested, and the shocking histamine link we discovered. This goes beyond gut health—it's about how your genes, hormones, and mood are all connected. I break down histamine intolerance, key symptoms, and how you might be unknowingly sabotaging your health. I TALK ABOUT:  06:40 – The functional medicine testing we did (Tiny Health code: BIOHACKINGBRITTANY, DUTCH Test, The DNA Company) 10:00 – Symptoms of gut issues and the genetic links to high histamine, estrogen dominance, and chronic symptoms 20:55 – Histamine-producing gut bacteria and symptoms of histamine intolerance 27:20 – Biomarkers to look for in your blood test (Siphox code: BIOHACKINGBRITTANY) 34:00 – What a low-histamine diet looks like (and what foods to avoid) 36:00 – The exact 6-week protocol we're using 38:00 - Phase 1: Pathogen Elimination (Designs for Health G.I. Microb-X, Progressive Labs GastroPro) 40:50 – Phase 2: Detox Support (GI Detox+, SH Stress Nutrients + SH Riboflavin, Xymogen OptiMag Neuro, BiOptimizers Magnesium Breakthrough code: BIOHACKINGBRITTANY, WeNatal code: BIOHACKINGBRITTANY) 43:08 – Phase 3: Microbiome Rebuilding (Designs for Health Floromyces, Seed Probiotic, BiOptimizers Probiotic code: BIOHACKINGBRITTANY) 44:30 – Phase 4: Hormone & Nutrient Optimization (BiOptimizers MassZymes code: BIOHACKINGBRITTANY, WeNatal & Men's Multi code: BIOHACKINGBRITTANY, Baja Gold Salt code: BIOHACKINGBRITTANY) 49:40 – What happens after the protocol ends and how to reintroduce foods SPONSORS: Most protein goes to waste—Masszymes by BiOptimizers helps you absorb it and actually build muscle. Use the code BIOHACKINGBRITTANY to get 10% OFF. RESOURCES: Optimize your preconception health by joining my Baby Steps Course today! Optimize your preconception health and fertility through my free hormone balancing, fertility boosting chocolate recipe! Download it now! Check out my upcoming luxury retreats and wellness events My Amazon storefront Dr. John Thomas, Functional Medicine Specialist   LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music

Four Fantastic Friends Podcast || Dare To Be Vital BookFIVE PRIMARY POINTS of the PODCAST1. Your Nose Could Predict Your LifespanA reduced sense of smell is significantly linked to early death. In a large study, each misidentified scent increased mortality risk by 5%. Missing 10+ scents raised the risk by 67%, especially from neurodegenerative diseases. Surprisingly, smell training has been shown to support cognitive function and well-being.2. A Selfie May Be a Scientific Vital SignAI tools analyzing facial features from selfies can estimate biological age and predict cancer survival better than chronological age. One model, FaceAge, correlated facial aging with the gene CDK6, a key player in cellular aging—suggesting that what we see in the mirror may reflect what's happening at the molecular level.3. Two Apples a Day Keep Inflammation AwayConsuming apples—especially Gala varieties—reduced inflammatory markers (CRP, IL-6), improved cholesterol, and enhanced antioxidant capacity in studies. Thanks to polyphenols and pectin, apples are a simple, data-backed intervention for improving vitality.4. Grip Strength Is the New SmokingLow grip strength, adjusted for body weight, is strongly linked to accelerated biological aging, chronic diseases, and premature death. It's a powerful, inexpensive, and practical biomarker. Boosting strength through resistance training is one of the most effective longevity tools.5. Optimism Extends LifeA positive mindset is scientifically linked to longer life—up to 15% longer for women and 11% for men. Optimistic individuals had a significantly higher chance of living to 85+. Optimism can be cultivated by reframing challenges and focusing on controllable responses.Four Fantastic Friends Podcast || Dare To Be Vital Book This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit vitalityexplorers.substack.com/subscribe

This special International Alzheimer’s Day episode features world-renowned nutritionist and author Patrick Holford, founder of Food for the Brain. Join Dr Ron Ehrlich and Patrick as they dismantle the outdated paradigm of amyloid-centric Alzheimer’s treatment and uncover how 99% of cases may be preventable through nutrition, biomarkers, and citizen-driven data.Learn how modern medicine’s reductionist mindset is failing us and how the future of cognitive health lies in big data, AI, and empowered lifestyle changes. Discover actionable insights into homocysteine, omega-3s, blood sugar, vitamin D, and glutathione, and why testing, not guessing is the key to preventing cognitive decline. Links in ShownotesPatrick Holford BOOKS https://www.patrickholford.com/books/Food For the Brain Website - https://foodforthebrain.orgCognitive Function Test (10 mins) Show notes are available at CLICK HERE CONNECT WITH DR RON & UNSTRESS HEALTH Join the Unstress Health Community: CLICK HERE INSTAGRAM: CLICK HERE YOUTUBE: CLICK HERE FACEBOOK: CLICK HERE TIKTOK: CLICK HERE SPOTIFY: CLICK HERE LinkedIn: CLICK HERE EMAIL: admin@unstresshealth.com DISCLAIMER: This podcast provides general information and discussion about medicine, health and related subjects. This content is not intended and should not be construed as medical advice or as a substitute for care by a qualified medical practitioner. If you or any other person has a medical concern, he or she should consult with an appropriately qualified medical practitioner. Guests who speak in this podcast express their own opinions, experiences and conclusions. See omnystudio.com/listener for privacy information.

 Most cancer drugs fail. Not because the science is wrong—because we're solving the wrong problems.The cost? Over $2 billion per failure. And for the patient waiting on a miracle—there's no second chance.Behind the headlines of “precision medicine,” there's a deeper story nobody's telling. Until now. 

In this episode of the RWS Clinician's Corner, Margaret and Brendan explore the powerful connection between metabolic health and mental well-being, revealing why mental health isn't just about psychology—but also about our biology. Brendan breaks down his “three pillars” model for true mental wellness, walks us through nuanced approaches to lab testing, and explains why functional practitioners should be both evidence-based and deeply empathetic.    In this interview, we discuss:  Brendan's early experiences with mental health struggles and his challenges with the conventional psychiatric approaches  The importance of distinguishing between psycho-emotional issues and neurological/physiological health The role of objective biomarkers in validating client experiences, as well as the potential pitfalls of over-identification with laboratory findings  Recognizing when to refer clients to mental health professionals  Techniques for addressing emotionally charged or traumatic material during sessions The Clinician's Corner is brought to you by Restorative Wellness Solutions.  Follow us: https://www.instagram.com/restorativewellnesssolutions/ Note: This episode contains discussions about suicide, which may be distressing to some listeners. Please take care of yourself and feel free to pause or skip this episode if needed. If you, a client, or someone you know is struggling with thoughts of suicide, help is available. Here is a list of free, confidential resources available 24/7: 988 Suicide & Crisis Lifeline: Call or text 988, or chat online at 988lifeline.org      -Crisis Text Line: Text HOME to 741741 to connect with a trained counselor      -The Trevor Project (for LGBTQ+ youth): Call 1-866-488-7386 or text START to 678-678 These services are here to support you anytime, anywhere. Remember, reaching out for help is a sign of strength.   Connect with Brendan Vermeire: Website: www.metabolicsolutionsllc.com Instagram: https://www.instagram.com/the_holistic_savage/   Use the discount code RW25 to get Brendan's FMHP Workshop Series for FREE: https://holisticsavage.kartra.com/page/FMHP-workshop   Timestamps:  00:00 "Functional Mental Health Insights" 05:46 "Passion for Healing Amid Struggle" 10:01 "Bridging Science with Spiritual Fitness" 13:28 "Mind-Body Connection Explored" 16:31 Objective Biomarkers vs. Mysterious Diagnoses 19:22 Navigating Functional Medicine Challenges 21:09 Mycotoxin Tests: Limited Diagnostic Insight 27:17 Neuroinflammation and Immune Biomarkers 30:11 Rethinking Lab Test Investments 32:52 Clinical Intake and Lifestyle Assessment 36:29 "Effective Patient Engagement Strategies" 41:13 Essential Advice for Health Practitioners 43:21 Bridging Coaching and Functional Medicine 46:14 "Understanding Test Limitations in Health" 49:43 Functional Mental Health Training Program 52:24 "Listener Requests and Gratitude" Speaker bio: Brendan Vermeire is a Clinical Researcher, Functional Medicine Practitioner & Educator, passionate about teaching a root-cause approach to mental and metabolic Illness. He is the proud owner of the Metabolic Solutions Institute, home of the Functional Mental Health Practitioner Certificate Program.   Keywords: metabolic health, mental health, functional medicine, biomarkers, neurological health, psycho-emotional health, lab testing, suicidal ideation, root cause medicine, functional practitioners, SSRI, psychiatric drugs, metabolic markers, personal training, clinical research, depression, anxiety, neuroinflammation, microbiome, mindset, metabolic dysfunction, mold illness, mycotoxins, stool testing, coaching, motivational interviewing, C-reactive protein, neurofilament light chain, neurotransmitters, patient compliance   Disclaimer: The views expressed in the RWS Clinician's Corner series are those of the individual speakers and interviewees, and do not necessarily reflect the views of Restorative Wellness Solutions, LLC. Restorative Wellness Solutions, LLC does not specifically endorse or approve of any of the information or opinions expressed in the RWS Clinician's Corner series. The information and opinions expressed in the RWS Clinician's Corner series are for educational purposes only and should not be construed as medical advice. If you have any medical concerns, please consult with a qualified healthcare professional. Restorative Wellness Solutions, LLC is not liable for any damages or injuries that may result from the use of the information or opinions expressed in the RWS Clinician's Corner series. By viewing or listening to this information, you agree to hold Restorative Wellness Solutions, LLC harmless from any and all claims, demands, and causes of action arising out of or in connection with your participation. Thank you for your understanding.  

In part two of this two-part series, Dr. Dan Ackerman and Dr. Trey Bateman discuss handling patient requests for blood-based biomarkers for Alzheimer disease and interpreting test results.

In this episode, I'm joined by Julia Geronimi from Servier and Dr. Pavel Mozgunov from the University of Cambridge to explore a topic that's absolutely central to advancing precision medicine—predictive biomarkers. We dive into the challenges of identifying predictive vs. prognostic biomarkers, especially in early-phase clinical trials with limited sample sizes. What makes their approach so exciting is that it offers a model-flexible, visually intuitive way to detect predictiveness—even before we talk about dichotomizing biomarkers or setting cutoffs. If you work on clinical trial design, translational science, or biomarker development, this conversation will give you fresh tools—and a lot to think about.

In part one of this two-part series, Dr. Dan Ackerman and Dr. Trey Bateman discuss current biomarkers for Alzheimer disease and how do you use them in clinic. 

AUA2025: Integration of Biomarkers, MRI and PSMA PET Imaging Into the Management of Prostate Cancer CME Available: https://auau.auanet.org/node/43069 At the conclusion of this CME activity, participants will be able to: 1. Evaluate recent advances in biomarkers and molecular imaging technologies and their role in improving the accuracy of prostate cancer staging, and treatment monitoring. 2. Identify the clinical scenario in which PSMA PET/CT is most helpful to identify the localization and extent of locoregional or systemic metastatic disease. 3. Identify the pitfalls of false-positive and false-negative PSMA PET/CT findings. 4. Apply the findings of PSMA PET/CT for the best individual therapeutic approach. 5. Identify patients with radiorecurrent organ-confined prostate cancer. ACKNOWLEDGEMENTS Support provided by independent educational grants from: Blue Earth Diagnostics, Inc. Lantheus Medical Imaging Novartis Pharmaceuticals Corporation

Dr. Olivier Salamin is the Operational Manager of the Lausanne Athlete Passport Management Unit (APMU) within the Swiss Laboratory for Doping Analyses at the Lausanne University Hospital (Centre Hospitalier Universitaire vaudois/CHUV). In this episode, he discussed his career and research on the discovery and validation of biomarkers to detect prohibited substances and methods, particularly related to the Athlete Biological Passport (ABP). He also gives us an inside look at the history and operations of the Lausanne APMU.

Dr. Dan Ackerman talks with Dr. Trey Bateman about the significance of blood-based biomarkers in Alzheimer disease. Purchase Annual Meeting On Demand to get access to the recordings and the ability to claim CME through March 1, 2026.  Disclosures can be found at Neurology.org.   

Recorded live during Boston Marathon weekend, this episode of Marni on the Move features Renee Deehan, Senior Vice President of Science & AI  at InsideTracker. We dive into the key blood biomarkers every runner, triathlete, and endurance athlete should track for optimal performance and recovery. Renee breaks down what the data reveals about overtraining, under-recovery, and how to identify early warning signs through your bloodwork. Plus, we explore InsideTracker's latest AI-powered tools designed to make personalized health insights more actionable than ever. Whether you're racing marathons or just trying to train smarter, this episode delivers must-know science to elevate your game. CONNECT InsideTracker on Instagram Marni On The Move Instagram, TikTok, LinkedIn, or YouTube` Marni Salup on Instagram and Playlist on Spotify SUBSCRIBE TO OUR NEWSLETTER Sign up for our monthly newsletter, Do What Moves You, for Marni on the Move updates, exclusive offers, invites to events, and exciting news! SUPPORT THE PODCAST Leave us a five stars and a review on Apple, it's easy, scroll through the episode list on your podcast app, click on five stars, click on leave a review, and share what you love about the conversations you're listening to. Tell your friends the episodes you are listening to on your social. Share a screen shot of the episode in your stories, tag us, we will tag you back! Subscribe, like and comment on our YouTube Channel, MarniOnTheMovePodcast

Dr. Greg Cooper and Dr. Joseph Therriault discuss the use of plasma biomarkers in diagnosing Alzheimer disease. Show reference: https://doi.org/10.1038/s43587-024-00731-y 

Dr. Greg Cooper talks with Dr. Joseph Therriault about the use of plasma biomarkers in diagnosing Alzheimer disease, emphasizing the importance of interpreting these biomarkers within the clinical context of the patient.  Read the related article in Nature. Disclosures can be found at Neurology.org. 

With so many conflicting studies and experts shouting from every corner, it's easy to lose sight of one simple truth: your body knows best. In this episode of the Primal Shift Podcast, I'm calling out the noise around “good” vs. “bad” foods and diving straight into the powerful signals your body sends every time you eat. From unexplained breakouts and weird cravings to stubborn heartburn and crashing energy levels, your physiology is practically begging you to pay attention. We'll explore how issues like bloating, bad breath, headaches, and even mood swings can be early warning signs that a particular food isn't working for you — no matter what the latest scientific study or diet guru claims. Yes, science and ancestral wisdom matter, but they mean little if you feel lousy every time you bite into certain foods. Think of it as detective work: noticing patterns between what you ate and how you slept, how your skin looks, or whether you're getting random joint pain or weird body odor. If you've ever felt guilty because some “healthy” item (like sourdough or raw milk) just doesn't sit right with you, this episode is your permission slip to trust yourself. It's not about demonizing specific foods; it's about becoming so in tune with your body that you can instantly tell the difference between a mild craving and a genuine sign of hunger — or a subtle symptom and a flashing red light. When in doubt, remember: if it doesn't feel good, it probably isn't good for you. Your unique biology is more than just numbers on a lab test or words in a research paper… it's an entire feedback system that never stops working.  So give yourself the freedom to listen, experiment, and (yes) sometimes say no to foods that simply don't serve you. Learn more: 18: What I Eat in an Animal-Based Diet + My Go-To Food Choices and Supplements: https://www.primalshiftpodcast.com/what-i-eat-in-an-animal-based-diet-my-go-to-food-choices-and-supplements/  The Best Diets for Weight Loss (And Which Ones to Avoid): https://michaelkummer.com/best-weight-loss-diets/  Thank you to this episode's sponsor, Peluva! Peluva makes minimalist shoes to support optimal foot, back and joint health. I started wearing Peluvas several months ago, and I haven't worn regular shoes since. I encourage you to consider trading your sneakers or training shoes for a pair of Peluvas, and then watch the health of your feet and lower back improve while reducing your risk of injury.  To learn more about why I love Peluva barefoot shoes, check out my in-depth review: https://michaelkummer.com/health/peluva-review/  And use code MICHAEL to get 10% off your first pair: https://michaelkummer.com/go/peluva  In this episode: 00:00 - Intro: Can you trust how food makes you feel? 00:51 - Biomarkers vs. short-term body signals 02:45 - How to listen to your body's feedback 05:00 - Subtle warning signs: skin, energy, mood, joints 07:00 - The truth behind food reactions: dairy, carbs, odor 09:49 - What feeling great actually feels like 10:30 - Final thoughts: Tune in to your body, not the noise Find me on social media for more health and wellness content: Website: https://michaelkummer.com/ YouTube: https://www.youtube.com/@MichaelKummer Instagram: https://www.instagram.com/primalshiftpodcast/ Pinterest: https://www.pinterest.com/michaelkummer/ Twitter/X: https://twitter.com/mkummer82 Facebook: https://www.facebook.com/realmichaelkummer/ [Medical Disclaimer] The information shared on this video is for educational purposes only, is not a substitute for the advice of medical doctors or registered dietitians (which I am not) and should not be used to prevent, diagnose, or treat any condition. Consult with a physician before starting a fitness regimen, adding supplements to your diet, or making other changes that may affect your medications, treatment plan, or overall health. [Affiliate Disclaimer] I earn affiliate commissions from some of the brands and products I review on this channel. While that doesn't change my editorial integrity, it helps make this channel happen. If you'd like to support me, please use my affiliate links or discount code. #HealthyDiet #FoodReactions #AnimalBasedDiet #CleanDiet    

In this episode, we sit down with Dr. Matthew Dawson, the founder and CEO of Wild Health, and leader in genomics-based precision medicine. Dr. Matt breaks down what precision medicine truly means--how it goes beyond traditional healthcare to create highly personalized plans based on your unique genetic blueprint and blood work. We explore some of the most important genes to assess for optimizing health, performance, and longevity, including the ApoE gene. He shares powerful insights into the future of medicine and why understanding your genetics is crucial for extending healthspan. Plus, we open up about our own personal Wild Health test results and how they've shaped our individual wellness journey. This conversation is packed with actionable insights you won't want to miss!Dr. Matthew Dawson is the founder and CEO of Wild Health, a genomics-based precision medicine company, and the CEO of TruDiagnostic, an epigenetics testing lab. He has authored two textbooks, published over two dozen studies, lectured in over 20 countries, and won national awards for education and innovation. His passion is unlocking the secrets of the genome and epigenome and using them to optimize health and maximize healthspan. He lives in the woods with his wife, four children, and two dogs.SHOW NOTES: 0:31 Welcome to the show!3:57 Dr. Matt Dawson's Bio4:40 Welcome Dr. Matt to the show!5:14 What is “Precision Medicine”?7:14 Your genes are not your destiny11:09 Renee's experience with Bulletproof coffee11:38 MTHFR & Homocysteine12:43 Combining lab work with genetics17:24 Alzheimer's genetics20:32 What to do for APOE-3/422:56 Biomarkers for optimal health 24:28 Can you change your sleep chronotype?28:26 Genes for telomere length31:37 *ALIGN MAT*33:16 *PIQUE TEA*35:27 Boosting BDNF37:30 Something new about HbA1C!39:47 FOXO3 Gene for Longevity43:40 Blue Zones & social connection45:12 Testing Biological Age49:08 Caloric Restriction for Longevity51:42 The perfect diet for your genes53:25 Comparing macro tolerances57:37 Wild Health reports 59:12 Coming soon for Precision Medicine!1:04:16 His final piece of advice1:04:56 Thanks for tuning in!RESOURCES:Website: wildhealth.com - discount code: BIOHACKERBABESInstagram: wildhealthmdLinkedIn: Wild HealthMy Align Mat - discount code: BIOHACKERBABES to save $250Pique Tea - Save $ with this link!Puori - Save 20% with discount code: BIOHACKERBABESEffecty - Save $50 with discount code: BIOHACKERBABESOur Sponsors:* Check out Effecty and use my code BIOHACKERBABES for a great deal: https://www.effecty.com* Check out Puori: https://Puori.com/BIOHACKERBABESSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands

What if you could take control of your health—before it's too late?

My guest is Dr. Chris Palmer, M.D., a board-certified psychiatrist and professor at Harvard Medical School. He explains how specific nutrition, exercise, supplement-based, and other factors can improve mitochondrial health and thereby provide relief from adult and childhood ADHD, bipolar disorder, schizophrenia, and symptoms of autism. We discuss mitochondrial biology, whether vaccines can impact inflammation and mitochondrial health, and the potential ramifications. We also review creatine, methylene blue, and urolithin A, as well as the role of B vitamins and iron in treating depression. By the end of this episode, you will understand the powerful link between metabolic health and mental health, and the lifestyle, dietary, and other factors you can leverage to help overcome common mental health challenges and disorders. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Our Place: https://fromourplace.com/huberman LMNT: https://drinklmnt.com/huberman Eight Sleep: https://eightsleep.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 Dr. Chris Palmer 00:02:15 Integrating Metabolic, Mental & Physical Health; Childhood Trauma & Risk 00:10:46 Sponsors: Our Place & LMNT 00:13:44 Depression Causes, Molecule Model?, Neuroplasticity?; Metabolism 00:22:20 Mitochondrial Functions, Stress Response, Mental Health 00:31:09 Sponsors: AG1 & Eight Sleep 00:33:59 Mitochondrial Health & 6 Pillars of Lifestyle Medicine 00:39:38 Stimulants, Mitochondria, Dopamine; Alcohol 00:45:47 Nicotine; Substance Use, Metabolic Health & Disease 00:52:23 Children, Energy & Metabolic Function; Diseases of Aging & Mental Disorders 00:59:18 Sponsor: Function 01:01:06 Diet & Metabolism; Ultra-Processed Foods, Additives, GRAS 01:09:30 Rebellious Spirit, Ultra-Processed Foods & Food Industry Funding 01:19:14 Ketogenic Diet, Epilepsy, Schizophrenia, Bipolar 01:22:52 Ketogenic Diet, Fasting & Mitochondria; Gut Microbiome, Brain Metabolism 01:30:06 Low-Fat Diets; Tool: Occasional Fasts; Ketogenic Diet; Intermittent Fasting 01:38:40 Nutrition Research, Food Industry Lobbyists; Ultra-Processed Foods, Addiction 01:46:55 Creatine & Mitochondrial Health 01:52:34 Methylene Blue & Mitochondria; Serotonin Syndrome 02:02:58 Urolithin A, Mitochondria Function; Supplements & Appropriate Use 02:11:14 Vitamin Deficiencies, Iron Deficiency 02:16:06 Vitamin B12 & Folate Deficiency, Autoimmune Disorders 02:24:48 Mental Illness & Root Causes 02:29:02 Vaccines, Inflammation, Mitochondria, Autism 02:39:17 Neurodevelopmental Disorder Onset & Follow-Up 02:45:31 Vaccines, Autism, Future Research; Mother Obesity & Diabetes 02:51:23 Father Obesity & Autism; Poor Metabolic Health, Blood Biomarkers 02:56:44 Assessing Metabolic Health & Biomarkers; National Institutes of Health (NIH) 03:02:59 Future Directions, Bridging Mental & Physical Health 03:09:27 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures