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Send us a textMost people say they want to live longer. Fewer stop to ask: what does “longer” actually feel like?In this episode, Dr. Kevin White joins Dr. Nicki Byrne and Dr. Matt Kaeberlein for a fast-moving, smart, and practical conversation about health span — and what it really takes to stay strong, clear, and independent as you age.The trio breaks down the four pillars of health (eat, move, sleep, connect) and how to apply them in real life. You'll hear stories from the clinic, data that matters, and the kind of takeaways you can actually use — whether you're a curious patient or a clinician trying to make sense of continuous glucose monitors, inflammatory markers, or why one of your patients still eats sardines.This is part one of a two-part conversation originally recorded for the OptiSpan Podcast, hosted by Dr. Kaeberlein. Stay tuned for part two, where they dig into blood work, hormones, LP(a), genetic testing, and the future of personalized longevity medicine.
Advanced biomarker testing and a personalized 100-day intervention to adjust biological age are at the heart of a new longevity venture called Hundred. The AI-driven platform uses data from wearable technology together with users' medical histories to devise individual health plans. Billed as a ‘doctor in your pocket,' the goal is to extend quality of life to a vibrant 100 years, through tailored insights and guidance. Hundred's founder, Tyler Smith, is spearheading an effort to redefine how we understand and manage aging. Citing his own startling results from biological age tests, as a catalyst for the venture, he is a passionate advocate for preventative health measures.In this conversation Smith shares his goals for the platform while Live Long host Peter Bowes pledges to try it out for 100 days. They also discuss the degree to which technology can replace traditional face-to-face medical consultations and address questions about entrusting our health to AI-driven solutions.JOIN HUNDRED NOWOptimize your healthspan and potentially lower your biological age. Tyler and the team at HUNDRED are offering $75 in credit for add-on tests and supplements from the HUNDRED marketplace when you sign up at https://www.hundred.com/partners/livelongpodcast Live Long host Peter Bowes is also joining HUNDRED to experience and critique the platform's protocols. Will it lead to a healthier and longer life? Daily updates starting in August, 2025Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts SpotifySupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
This episode discusses the Food and Drug Administration and National Institutes of Health Biomarker Working Group updates to the original 2018 BEST Resource in 2021, including the understanding and classification of biomarkers like BRCA1 and BRCA 2. This presentation highlights how these changes affect cancer risk diagnostics and provides a resource for evidence-based application of specific genetic testing in the pharmacist's clinical practice. CE for this episode expires two years after its original publication date. The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.
Dr. Trey Bateman and Dr. Gregg Day discuss the study design, findings, and clinical implications of using plasma biomarkers in real-world patient care. Show reference: https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.70316
BUFFALO, NY - July 18, 2025 – A new #editorial was #published in Volume 16 of Oncotarget on July 16, 2025, titled “microRNAs in soft tissue sarcoma: State of the art and barriers to translation.” In this article, Elizaveta K. Titerina, Alessandro La Ferlita, and Joal D. Beane from Ohio State University discuss the role of microRNAs in soft tissue sarcomas (STS), a rare and diverse group of cancers that begin in connective tissues, like bone or fat. The authors explain how these small molecules regulate cancer-related processes and highlight their potential as non-invasive biomarkers for diagnosis and monitoring. They also outline the main challenges that need to be addressed before microRNA-based strategies can be used in clinical settings. Soft tissue sarcomas include over 50 subtypes, making precise diagnosis and effective treatment difficult. The editorial describes how microRNAs influence cancer growth, spread, and response to therapies. Because microRNAs are stable in body fluids like blood and saliva, they could be used for early detection and to help guide treatment decisions. Such as, certain groups of microRNAs are linked to how patients respond to specific drugs, showing their potential as tools for precision medicine. “For example, miR-17-92 and miR-106b-25 clusters have been associated with sensitivity or resistance to eribulin in STS.” The authors also explain that microRNAs could help distinguish between tumor types that are often difficult to differentiate, such as benign lipomas and malignant liposarcomas. Recognizing these differences is crucial for guiding treatment decisions. Specific patterns of microRNA expression in blood samples may enable clinicians to make quicker and more reliable diagnoses without the need for invasive procedures. Beyond their diagnostic role, microRNAs are also being explored as therapeutic tools, but applying microRNA-based therapies to patients remains challenging. These molecules can act as either cancer promoters or suppressors, depending on the environment, which complicates the development of safe and targeted treatments. However, new delivery methods such as lipid nanoparticles show promise in improving precision and safety. Overall, microRNAs are emerging as an important focus in STS research, offering new possibilities for advancing diagnosis, prognosis, and treatment. As researchers continue to address the current challenges, these small molecules could become valuable tools in improving cancer care. DOI - https://doi.org/10.18632/oncotarget.28754 Correspondence to - Joal D. Beane, joal.beane@osumc.edu Video short - https://www.youtube.com/watch?v=MlLGA8BObPQ Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28754 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, soft tissue sarcoma, liposarcoma, microRNA, small non-coding RNA, cancer biomarkers To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM
Dr. Trey Bateman talks with Dr. Gregg Day about the study design, findings, and clinical implications of using plasma biomarkers in real-world patient care. Read the related article in Alzheimer's & Dementia. Disclosures can be found at Neurology.org.
Prostate cancer remains the most commonly diagnosed cancer and second leading cause of cancer death among men in the U.S., with evolving screening and treatment practices reshaping care in 2025. UCSF's Dr. Matthew Cooperberg highlights a shift away from overdiagnosis and overtreatment of low-risk cancers, focusing instead on identifying aggressive disease through tools like MRI and advanced biomarker tests. A new “smarter screening” model now guides primary care, recommending long testing intervals for men with low PSA levels. While active surveillance has increased nationally, significant variation in care remains, and racial disparities—especially for Black men—persist. Patients are encouraged to take time in making treatment decisions, as prostate cancer often progresses slowly and allows for thoughtful, personalized care. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40796]
Prostate cancer remains the most commonly diagnosed cancer and second leading cause of cancer death among men in the U.S., with evolving screening and treatment practices reshaping care in 2025. UCSF's Dr. Matthew Cooperberg highlights a shift away from overdiagnosis and overtreatment of low-risk cancers, focusing instead on identifying aggressive disease through tools like MRI and advanced biomarker tests. A new “smarter screening” model now guides primary care, recommending long testing intervals for men with low PSA levels. While active surveillance has increased nationally, significant variation in care remains, and racial disparities—especially for Black men—persist. Patients are encouraged to take time in making treatment decisions, as prostate cancer often progresses slowly and allows for thoughtful, personalized care. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40796]
Prostate cancer remains the most commonly diagnosed cancer and second leading cause of cancer death among men in the U.S., with evolving screening and treatment practices reshaping care in 2025. UCSF's Dr. Matthew Cooperberg highlights a shift away from overdiagnosis and overtreatment of low-risk cancers, focusing instead on identifying aggressive disease through tools like MRI and advanced biomarker tests. A new “smarter screening” model now guides primary care, recommending long testing intervals for men with low PSA levels. While active surveillance has increased nationally, significant variation in care remains, and racial disparities—especially for Black men—persist. Patients are encouraged to take time in making treatment decisions, as prostate cancer often progresses slowly and allows for thoughtful, personalized care. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40796]
Prostate cancer remains the most commonly diagnosed cancer and second leading cause of cancer death among men in the U.S., with evolving screening and treatment practices reshaping care in 2025. UCSF's Dr. Matthew Cooperberg highlights a shift away from overdiagnosis and overtreatment of low-risk cancers, focusing instead on identifying aggressive disease through tools like MRI and advanced biomarker tests. A new “smarter screening” model now guides primary care, recommending long testing intervals for men with low PSA levels. While active surveillance has increased nationally, significant variation in care remains, and racial disparities—especially for Black men—persist. Patients are encouraged to take time in making treatment decisions, as prostate cancer often progresses slowly and allows for thoughtful, personalized care. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40796]
Prostate cancer remains the most commonly diagnosed cancer and second leading cause of cancer death among men in the U.S., with evolving screening and treatment practices reshaping care in 2025. UCSF's Dr. Matthew Cooperberg highlights a shift away from overdiagnosis and overtreatment of low-risk cancers, focusing instead on identifying aggressive disease through tools like MRI and advanced biomarker tests. A new “smarter screening” model now guides primary care, recommending long testing intervals for men with low PSA levels. While active surveillance has increased nationally, significant variation in care remains, and racial disparities—especially for Black men—persist. Patients are encouraged to take time in making treatment decisions, as prostate cancer often progresses slowly and allows for thoughtful, personalized care. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 40796]
While most people regularly check their blood pressure or glucose, few consider routinely assessing their body's ability to move—and yet, this may be just as crucial to long-term health. Andrew Menter, CEO of Physmodo, joined Peter Bowes to explore the software company's mission to raise the profile of movement as a vital sign of good health. Andrew shares his personal journey from a career in law and finance to entrepreneurship in movement science, motivated in part by his athletic pursuits and the injuries that accompanied them. He discusses Physmodo's innovative use of computer vision technology, enabling self-assessment of mobility and posture via simple smartphone or tablet tools—making this once-specialized information accessible to everyone, not just elite athletes. He highlights the power of early intervention, the surprising ways movement influences sleep and mental health, and the growing importance of personalized preventive care. PartiQlar supplementsEnhance your wellness journey with PartiQlar supplements. No magic formulas, just pure single ingredients, like NMN, L-Glutathione, Spermidine, Resveratrol, TMG and Quercetin. Get a 15% discount with the code MASTERAGING15 at PartiQlarSupport the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.
Welcome to the sixth season of the Dementia Researcher X ISTAART PIA Relay Podcast. This series features interviews with ISTAART PIA committee members talking about their research, the research landscape of their fields, and the work of the ISTAART Professional Interest Areas (PIA) they represent. As we build up to the Alzheimer's Association International Conference in Toronto, join us for daily episodes that showcase the remarkable work being done in various research fields. -- In this Relay Podcast episode, Dr Colin Groot interviews Dr Marta Del Campo, Head Fluid Biomarker Facility; Ramón y Cajal Research fellow at BarcelonaBeta Brain Research Center and chair of the ISTAART Biofluid Based Biomarkers PIA. Together, they talk about recent advances in fluid biomarkers in dementia research, and explore the growing role of plasma biomarkers, integration with clinical trials, challenges with reproducibility and diversity, and the promise of proteomics and AI. Marta also reflects on the work of ISTAART, their plans for AAIC, the value of publishing negative findings, and why ISTAART offers vital opportunities for early career researchers. -- The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) convenes the global Alzheimer's and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer's and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 30 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit: http://www.istaart.alz.org Note: ISTAART Membership is free for students worldwide, and for researchers of all levels based in Low- and Middle-Income Countries. -- To book your place at this year's AAIC (In-person and online) visit: http://www.aaic.alz.org -- Find more information on our guests, and a full transcript of this podcast on our website at: http://www.dementiaresearcher.nihr.ac.uk/podcast -- The views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.
Please Support the Podcast: If you are enjoying, do me a small favour which helps a lot - subscribe and leave a review on your preferred podcast platform. Your support helps us bring valuable conversations like this one to a wider audience. Today I sit down with Martijn Arns, a biological psychologist at the forefront of applied neuroscience, to discuss the advancements and challenges in psychiatry. We delve into his pioneering research on brain biomarkers, the promising applications of brain stimulation techniques like Transcranial Magnetic Stimulation (TMS), and how lifestyle factors may influence conditions such as ADHD. Martijn also shares cutting-edge insights into the role of heart-brain coupling and the potential impact of psychedelics in mental health treatment, offering a glimpse into the future of personalised and stratified psychiatry. What You'll Learn: Understanding Biological vs. Clinical Psychology: Martijn explains the focus of biological psychology in studying brain activity rather than engaging in traditional talk therapy. The Role of Biomarkers in Psychiatry: Discover the challenges of seeking biological signatures for psychiatric conditions. Understand why a biomarker-driven psychiatry might be theoretically impossible due to clinical impairment and situational variables. Innovations in Brain Stimulation: Explore the mechanisms and applications of TMS for treating depression and other psychiatric disorders. Learn about the groundbreaking use of heart rate to optimise TMS targeting, enhancing treatment effectiveness. Lifestyle Factors and ADHD: Understand the significant role sleep and sunlight exposure play in ADHD symptoms. Consider the implications of lifestyle interventions in managing and reducing ADHD diagnoses. The Exciting Future of Psychiatric Treatments: Dive into how psychedelics might transform therapeutic approaches with their profound effects in combination with therapy. Reflect on the potential shift from daily medication to periodic brain stimulation treatments. Key Takeaways: Psychiatry is evolving, with innovations in neuroscience paving the way for more personalised and effective treatments. There's a growing recognition of the importance of lifestyle factors, like sleep and sunlight exposure, in influencing mental health conditions, especially ADHD. Advancements like TMS offer hope, showing potential even where conventional treatments have failed. Future therapies may focus more on brain stimulation and targeted interventions rather than a one-size-fits-all medication approach. Resources: For more insights and updates on cutting-edge neuroscience research, visit Brain Clinics at brainclinics.com. Connect with Martijn Arns on LinkedIn to follow his latest work in applied neuroscience. Share this episode with someone who might benefit from these insights—understanding and innovation in psychiatric treatment are vital as we move towards a future of tailored mental health care. 00:40 Biological vs. Clinical Psychology 01:38 Journey Through Academia and Early Career 04:04 Starting Brain Clinics and Translational Research 06:48 Challenges in Psychiatric Diagnosis 16:20 Stratified Psychiatry and Biomarkers 27:26 Transcranial Magnetic Stimulation (TMS) 31:25 Ethical Considerations in TMS Treatment 32:40 Future of Brain Stimulation Treatments 33:34 Personal Experiences with TMS and Psychedelics 34:23 TMS Applications Beyond Depression 36:02 Innovations in TMS Targeting 37:21 Heart-Brain Coupling and TMS 40:18 Exploring the Vagus Nerve and Depression 47:39 Sleep's Role in ADHD 55:59 Lifestyle Factors and ADHD 01:00:34 Exciting Ventures in Brain Research See omnystudio.com/listener for privacy information.
The Cleveland Clinic is in the third year of a first-of-its-kind brain study that was launched in 2022. The aim of the study is to identify biomarkers for neurological disorders earlier and either slow the progression or stop the progression all together. It's estimated that 1 in 6 people worldwide live with a neurological disorder—a broad term that can include Alzheimer's, epilepsy, multiple sclerosis, Parkinson's, and stroke among others. The study is expected to last for 20 years. Currently, more than 3,500 people from 46 states including Northeast Ohio are taking part in the study. But more participants are needed. Later, we talk to historian and author Brandy Schillace, Ph.D., about her new book, “The Intermediaries: A Weimar Story.” The book traces the story of the founding of the Institute for Sexual Science, the world's first center for homosexual and transgender rights. We conclude the show with the latest episode of our podcast, “Shuffle.”
In this episode, Dr. Vignesh Devraj explores the often-overlooked but deeply important topic of identifying vata imbalances using modern tools and Ayurvedic insights. Unlike pitta and kapha, vata is subtle, formless, and harder to diagnose through conventional means. Dr. Vignesh offers a practical and scientific lens to understand how deficiencies often signal a vata imbalance. From vitamin and hormone levels to HRV and VO2 Max, this episode is a deep dive into recognizing and balancing this elusive dosha using both ancient wisdom and modern technology. Sign up for a free episode abstract: vigneshdevaraj.comEpisode HighlightsWhy is vata intangible and difficult to measureModern blood markers that signal high vataThe connection between vitamin deficiencies and mental healthGut health & sleep quality for regulating vataLifestyle changes to ground and restore balanceWhy vata disorders are the most challenging to treat in AyurvedaTimestamps00:00 – 05:30 - Vata Imbalance & Biomarkers 05:30 – 10:30 - Why Vata Needs Lifestyle Correction10:30 – 12:17 - Modern Diseases & Vata CorrelationIf you are interested in doing one on one Ayurvedic consultation with Dr Vignesh Devraj, please find the details in this link: https://calendly.com/drvignesh/30-minute-session-with-dr-vignesh-devraj-md-ay-istIf you are economically challenged, please use the form provided to request a free Ayurvedic consultation here. (or copy paste this in your browser: https://docs.google.com/forms/d/e/1FAIpQLSd29nHcrC1RssR-6WAqWCWQWKKJo7nGcEm8ITEl2-ErcnfVEg/viewform )You can also visit us at Sitaram Retreat, for bookings check out: www.sitaramretreat.com BALANCE THE MIGHTY VATA - ONLINE COURSE NOW AVAILABLE What makes Ayurveda unique in its treatment approach is its practical wisdom on the concept of Vata. Vata is responsible for Prana - the life energy, nervous system - the master panel of our body, and our emotions. In Ayurveda, it is mentioned that controlling Vata is the most difficult part of healing and recovery. Recently, I have recorded a workshop on - Balancing The Mighty Vata which has over 6 hrs of content, with notes filled with practical inputs that can be integrated into our life. You can access this at https://drvignesh.teachable.com/For further information about Dr Vignesh Devraj, kindly visit www.vigneshdevraj.com and www.sitaramretreat.com Instagram - @sitarambeachretreat | @vigneshdevrajTwitter - @VigneshDevrajWe truly hope you are enjoying our content. Want to help us shape and grow this show faster? Leave your review and subscribe to the podcast, so you'll never miss out on any new episodes. Thanks for your support.Disclaimer: - The content of the podcast episodes is not intended to be a substitute for professional medical procedures, consultations, diagnosis, or treatment in any manner. We strongly do not recommend using the content of these episodes as medical advice for any medical conditions for you, others, or for treating your patients
BUFFALO, NY — July 8, 2025 — As populations worldwide continue to age, understanding the mechanisms and manifestations of cognitive aging is increasingly urgent for science, medicine, and society. Age-related cognitive decline ranges from mild memory lapses to the onset of dementia, and is shaped by a complex interplay of molecular, cellular, systemic, and social determinants. In this special collection, Aging (Aging-US) seeks to bring together cutting-edge research that spans the cellular and molecular underpinnings of cognitive aging with insights into the psychosocial, behavioral, and environmental factors that modulate its course. By integrating basic biology with translational and societal dimensions, this collection aims to foster a holistic understanding of how and why cognitive function changes with age—and what can be done to preserve it. We welcome original research articles, reviews, and perspectives across model systems and human studies, particularly those that promote interdisciplinary insights and translational potential. POTENTIAL TOPICS Molecular and Cellular Mechanisms -Senescence, inflammation, and neurodegeneration in cognitive decline -Mitochondrial dysfunction and oxidative stress in aging neurons -Neurovascular aging and blood-brain barrier integrity -Single-cell and spatial transcriptomics of the aging brain -mTOR, autophagy, and proteostasis in age-related cognitive impairment -The role of glial cells (microglia, astrocytes) in brain aging Genetics and Biomarkers -Genetic risk factors and epigenetic modifications associated with cognitive aging -Biomarkers of cognitive resilience and vulnerability -Neuroimaging and fluid-based biomarkers in aging populations Interventions and Lifestyle Factors -Cognitive benefits of caloric restriction, exercise, or senolytic therapies -Preclinical and clinical trials targeting aging pathways to prevent cognitive decline -Impact of sleep, nutrition, and metabolic health on cognition in older adults -Use of cognitive strategies and compensatory techniques to maintain or enhance function in aging Environmental and Social Contexts -Impact of social isolation, education, and socioeconomic status on cognitive trajectories -Lifelong cognitive reserve and its determinants -Cross-cultural and demographic studies on aging and cognition -Digital health tools for monitoring or enhancing cognitive function in the elderly SUBMISSION DETAILS: -Submission Deadline: March 31, 2026 -Manuscript Format: Please follow the journal's submission guidelines -Peer Review: All submissions will undergo a rigorous peer-review process -Submission Link: https://aging.msubmit.net/cgi-bin/main.plex To learn more about the journal, please visit our website at https://www.Aging-US.com and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
In this conversation, Professor S. Jay Olshanskydiscusses the evolution of aging science, the realistic limits of human life expectancy, and the concept of the Longevity Dividend, which emphasizes the health and economic benefits of modulating the aging process. He also explores the potential of biomarkers in predicting longevity, the societal implications of an aging population, and the ethical considerations surrounding advancements in longevity science. Learn more about Professor S. Jay Olshansky: http://sjayolshansky.com/sjo/Background.html - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/
Join Dr. Martin in today's episode of The Doctor Is In Podcast.
This episode discusses the use of Platelet Factor 4, which has several roles for applicability, limitations, and emerging areas for use. CE for this episode expires two years after its original publication date. The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.
Episode 5 – Strategies for Optimal Aging: Leveraging Nutrition and Fitness for Practitioner and Patient Dr. Sarah Clarke, DC interviews Dr. Kimberly Besuden, DC, CFMP In this lively conversation, Dr. Besuden, DC, CFMP, shares all of her tips, tricks and recommendations for aging optimally and gracefully. Drs. Sarah and Besuden discuss strategies for maintaining healthy habits and routines for practitioner and patient alike. This episode is full of gems including specific supplementation to fill nutrition gaps, easy-to-maintain exercise routines, and a deep dive into hormesis practices. Dr. Kimberly Besuden is a Chiropractor and Certified Functional Medicine Practitioner; owner of The Health Factor; and owner of Bay Street Wellness. She has a long history as a competitive athlete, extensive training in clinical nutrition, and many years working as a personal trainer and strength coach. · 1:30 Inspiration to become a Chiropractor · 3:30 Inspiration to pursue Functional Medicine and Detox and Purification · 5:00 Dr. Besuden's Clinical Practice · 5:45 Active Lifestyles for Aging Populations · 8:50 Strength Training for the Aging Population – key for optimal aging, and connection between strength training and naturally increased GLP-1 · 13:00 Tips for sticking with a strength training routine – for practitioners and patients · 16:15 Hormesis and it's role and optimal aging – HIIT, hot and cold therapy, intermittent fasting · 21:18 Intermittent Fasting · 26:10 Maintaining healthy diets and habits with busy schedules and traveling · 29:05 Hot and cold therapy · 30:50 The Modified Mediterranean Diet – low carb, healthy fats, moderate protein · 38:55 Super foods for training · 41:20 Biomarkers, body composition, and metrics – equipment, devices and best practice · 45:30 Bloodwork Panels and Supplementation for Nutritional Gaps · 48:00 Other Diet and Lifestyle Recs for optimal aging · 50:58 Final thoughts for practitioners – Practice what you preach
Should We Measure Biomarkers for PPMI Definition
In this episode, Dr. Michael Lustgarten discusses his research on the gut microbiome, serum metabolome, and muscle health in older adults. He shares insights from his journey into the world of aging, the importance of data in health optimization, and the emerging concept of the gut-muscle axis. Dr. Lustgarten emphasizes the significance of metabolites in predicting longevity and the need for personalized health tracking. He also addresses the balance of exercise and the role of fecal microbiota transplantation in health. Learn more about Dr. Michael Lustgarten: https://nutrition.tufts.edu/academics/faculty/michael-lustgarten - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/
In this episode of the Flex Diet Podcast, I'm diving into the nitty-gritty of blood work and why it matters for your health, performance, and longevity, especially if you're an athlete, bodybuilder, or serious about your training.Fresh off the ISSN (International Society of Sports Nutrition) conference, I'm joined by Michael Warner, a sharp coach at Marek Health and the owner of Set the Standard. Together, we unpack some of the most important markers in blood work, how training and nutrition can influence your results, and how to actually interpret those lab numbers in the real world.We also discuss the importance of hydration, the context behind the numbers, and why proactive health monitoring should be an integral part of every performance plan. And yes, we touch on the impact of PEDs (performance-enhancing drugs) and what they can do to your blood markers.Whether you're optimizing for gains or longevity, this is a must-listen for anyone who wants to truly understand what's going on under the hood.Sponsors:Tecton Life Ketone drink! https://tectonlife.com/ DRMIKE to save 20%LMNT electrolyte drink mix: miketnelsonlmnt.comAvailable now:Grab a copy of the Triphasic Training II book I co-wrote with Cal Deitz here.Episode Chapters:00:16 Recap of the ISSN Meeting00:40 Guest Introduction: Michael Warner00:59 Importance of Blood Work for Health and Performance01:28 Personal Experience with Blood Work02:15 Basic Blood Tests and Their Accessibility03:19 Interpreting Blood Work Results03:37 Vitamin D and Lifestyle Factors04:08 Focus on Exogenous Compounds04:31 Sponsor Shoutouts06:48 Interview with Michael Warner Begins08:04 Blood Work in Physique Athletes08:57 Variability in Blood Work Results13:21 Blood Pressure and Easy Checks15:01 Proactive Health Monitoring15:48 Whack-a-Mole Lab Work19:11 Preparing for Lab Work26:33 Frequency of Blood Work29:45 Enhanced Athletes and Blood Work33:08 Risks and Rewards of Enhancement35:57 TRT and Personal Experiences38:18 Fertility and Performance Enhancing Drugs39:03 Introduction to Fertility Clinics and At-Home Sperm Tests40:27 Misconceptions About Testosterone and Fertility41:26 Essential Blood Work for Health and Performance44:26 Advanced Markers and Kidney Function46:25 Importance of Iron Panels and Sex Hormones50:16 Thyroid Panels and Additional Health Markers54:56 Merrick Health and Telemedicine Services01:04:22 Conclusion and Final Thoughts Flex Diet Podcast Episodes You May Enjoy:Episode 201: Coaching clients to look and feel their best: An interview with Lacey Dunn, RDEpisode 144: Peptides – Bleeding Edge Performance, Muscle, and Recovery with Dr. Andy Galpin & Dr. Ryan GreeneConnect with Michael:Instagram: https://www.instagram.com/mawsome_Website: https://marekhealth.com/Get In Touch with Dr Mike:Instagram: DrmiketnelsonYouTube: @flexdietcertEmail: Miketnelson.com/contact-us
Drs. Zaman and Podolanczuk discuss data for new and emerging therapies for ILD presented at ATS 2025, including nerandomilast, inhaled therapies for IPF and ILD, TNIK inhibitors, as well as new biomarkers and imaging for diagnosing ILDs.
We're in Maulbronn Germany - at the pre-conference sessions!We catch up with Professor Fehlings and discuss all things early intervention, genetics, biomarkers, being curious, asking questions and the blend of research and clinical work and the call of implementation!Be sure to visit the m:con Mannheim YouTube channel for the special video-casts we created for the Pre-Conference - all set in the beautiful location of Maulbronn Monastery - a UNESCO world heritage site!The video-casts will be available on the mconmannheim YouTube channel over the course of the conference and mirrored to the ResearchWorks YouTube channel after the conference too!https://www.youtube.com/@mconmannheim/videos
Drs. Sood and Liu discuss emerging and investigational biomarkers for interstitial lung disease and their potential utility as predictors of progression or as tools for tailoring therapy.
Gabrielle Liu, MD, MS and Namita Sood, MD, FCCP discuss advances and future treatment targets for interstitial lung disease including some that are still under investigation.
Send us a textDr. Michael Koren joins Kevin Geddings to explain biomarkers, which he describes as biological indicators that may mark the presence of disease. Researchers are increasingly looking at biomarkers for their potential in early detection of disease before symptoms appear. Dr. Koren brings it home with a personal story of how current research studies looking into lung cancer biomarkers may have real-world effects for participants.Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!
In this week's episode, we'll learn more about social determinants of health that impact access to allogeneic hematopoietic cell transplantation in patients with acute myeloid leukemia, or AML; use of megakaryocyte growth factor receptor-based stem cell depletion as part of pretransplant conditioning in ex vivo autologous gene therapy; and identification of an eight-protein risk signature as well as a novel single protein biomarker, soluble oncostatin M receptor, for risk stratification in AML.Featured Articles:Social Determinants of Health and Access to Allogeneic Hematopoietic Cell Transplantation for Acute Myeloid LeukemiacMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pretransplant ConditioningBlood-Based Proteomic Profiling Identifies OSMR as a Novel Biomarker of AML Outcomes
This episode highlights changes made to the resource and revised categories of biomarkers and provides a resource for evidence-based application of biomarkers in clinical pharmacy practice. CE for this episode expires on June 21, 2027. The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.
This week, we present an inspiring episode for anyone interested in the history, present, and future of prostate cancer care. In this Legends in Urology installment of the BackTable Urology Podcast, Dr. Gerald Andriole joins guest host Dr. Niraj Badhiwala to reflect on a career that has left a lasting impact on the field. --- SYNPOSIS Dr. Andriole shares personal stories from his upbringing in Northeastern Pennsylvania and his journey into medicine. He reflects on his expedited education through Penn State and Jefferson Medical College and his path to urology. He discusses his pivotal work in prostate cancer screening, including the influence of major trials like The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial, and traces the evolution of surgical and diagnostic techniques. The conversation also touches on current innovations and the future of prostate cancer management, offering valuable advice for the next generation of urologists. --- TIMESTAMPS 00:00 - Introduction01:59 - From Childhood to Medical School06:48 - Discovering Urology16:52 - Pioneering Prostate Cancer Screening24:07 - The PLCO Study: Design and Challenges28:57 - Controversies and Criticisms in Prostate Cancer Screening33:29 - Evolving Practices in Prostate Cancer Management44:19 - Future of Prostate Cancer Treatment
This episode featuring clinician-scientist and expert in liquid biopsy development, Dr. Lindsey Cotton, who explores the evolving science of lung cancer biomarkers and their role in early detection. Listen in to learn more about the current landscape, benefits and challenges of both organ-specific and multi-cancer tests. The highly informative discussion aims to clarify what these tests can and cannot tell us today, along with a forecast for tomorrow.
In this conversation, Dr. Jeffrey Gladden, a longevity doctor and author, shares his journey from traditional medicine to the field of longevity and health optimization. He discusses the importance of understanding thyroid function, mental well-being, and the personal meaning of longevity. Dr. Gladden outlines five key circles of longevity, emphasizes the role of biomarkers in assessing health, and shares daily habits that contribute to a youthful life. He also delves into testosterone optimization, innovative approaches to cardiovascular health, and the critical role of the nervous system in overall wellness. Finally, he highlights exciting future projects in the field of longevity medicine.Chapters00:00 Introduction to Longevity and Health02:11 Dr. Gladden's Personal Journey to Longevity08:41 Defining Longevity and Its Meaning11:58 The Five Circles of Longevity18:13 Biomarkers of Aging and Youthfulness24:19 The Importance of Enjoying Exercise28:19 Understanding VO2 Max and Cardio Training31:19 The Role of the Nervous System in Strength Training32:01 Testosterone Optimization and Its Challenges40:00 Innovations in Longevity and Health
Wellness + Wisdom | Episode 750 Does AI hold the key to fixing the modern healthcare system that's keeping us sick? Nathan Graville, CEO + Co-Founder of Geviti, joins Josh Trent on the Wellness + Wisdom Podcast, episode 750, to reveal why “feeling good” and “being healthy” are two very different things, how routine blood tests can expose hidden inflammation before it becomes disease, why reactive care driven by Big Pharma benefits from keeping you sick, and how AI doctors can help you reclaim ownership of your health. "Within the next 5 years, everybody is going to have an AI doctor in their pocket, and the whole traditional healthcare system is going to be reshaped forever. That's how we make longevity accessible to everybody, and it will be completely normal to live into our 120s, 130s, 140s." - Nathan Graville 20% Off Geviti Geviti offers cutting-edge health solutions tailored to various wellness needs, from longevity and hormone health to weight management and sexual vitality. Geviti's personalized approach includes regular consultations and follow-up tests, ensuring that each aspect of a customer's health regimen is optimized for their current state of health. Whether you're addressing specific health issues or aiming to enhance overall well-being, Geviti's comprehensive testing and personalized health plans provide the tools and support necessary for achieving optimal health. 20% OFF GEVITI Use code JOSH20 at checkout In This Episode, Nathan Graville Uncovers: [01:05] Feeling Good ≠ Healthy Nathan Graville Geviti Why feeling fine doesn't mean that we are healthy. How being fit doesn't equal being healthy. The importance of getting blood tested. Why doctors usually don't test C-reactive protein. [05:15] Proactive Health Care Why proactive care is the only way to achieve true health. How Big Pharma benefits from us being sick. What tools can help us measure our health. How preventative care has become more accessible in the past 10 years. [08:05] How to Optimize Your Health for Longevity Why longevity doctors are extremely expensive and hard to find. How AI makes longevity accessible to everybody. Why longevity shouldn't be obsessive. The role of mental health in our lifespan. How traditional healthcare is going to change with the rise of AI. [13:30] AI Bias: Can You Really Trust ChatGPT? How AI is evolving faster than we think. Why people assume that every output AI provides is accurate. How AI gives us very convincing responses to things we don't know anything about. Why the right prompting creates more valid results. The longer we collect our data with Geviti, the better data it gives us about our health. [19:05] From Grief to Helping Others Why Nathan believes his father still exists in a different form after passing. How Geviti could have saved his father. Why the pandemic made it difficult to get proper care. How Nathan created Geviti to honor his father. Why Nathan changed his opinion on psychotherapy. How therapy helped him heal through being vulnerable. [28:10] Modern Health Care Is A Profit-Making Machine Why the medical system is good at fixing injuries. How reactive care is highly profitable, and there's an incentive to keep people sick. Why Make America Healthy Again draws attention to the problems of the healthcare system. How we shouldn't expect our doctors to own our health. Why we need to take down Big Pharma. How Geviti is not profit first, but people first. [34:45] Are You Living to Work? Conscious Capitalism by John Mackey + Raj Sisodia How our bodies respond to nervous system dysregulation. Why we are misaligned in our priorities, and we live to work. How Nathan puts God first, family second, and work third. [39:10] Biological Age Testing How Josh discovered that his biological age was much younger than his chronological age. Why getting blood work is the first step, then we need to take action. How Geviti provides practical tools and a team to support your journey. Why assessing biological age has changed and there are several different methods. How biological age testing shows how we're improving our longevity. Why basic lifestyle changes can decrease our biological age. [46:35] Methylation + Supplementation 734 Kirk Parsley MD | Sleep As Medicine: How To Sleep Like Royalty + Stop Being Sick How Geviti ensures the accuracy of their lab tests. What labs they're working with for diagnostic solutions. 694 Shawn Wells | Your Ultimate Guide To Healing Mental + Physical Health How 30-40% of people struggle with methylation. Why many supplements are not bioavailable and don't absorb into the body. How supplements are meant to be used for the best effect. Why supplementation must be data driven. [54:55] Can You Rely on Technology with Your Health? NOOTOPIA (10% off with code JOSH10) How older generations don't trust technology as much as younger people. Why we can't hear what our body's telling us it needs. How Geviti protects their clients' data. Why technology is a part of human evolution. How using technology doesn't mean we're going against nature. [01:00:45] Peptides: Nature's Miracle? Peptides already exist in our bodies and are completely natural. How peptides bind to the receptors of our cells and support healing. Why peptides are a threat to Big Pharma. How exogenous growth hormones can cause serious health issues. Why we should only buy peptides from pharmacies. How research chemical companies produce peptides that can be very harmful. [01:09:15] The Future of Health Why Eli Lilly is going against compounding pharmacies. We need more compounding pharmacies in order to make health products more accessible. How we can decentralize health information. Why we could invent cures to all diseases if we established a decentralized database. How human nature might stop us from creating a new system. [01:16:20] Trust Your Intuition Why everyone has access to intuition. How our intuition gets clouded. Why people fall for snake oil supplements. How we can judge a company by their founder. Why we always have a gut feeling at the beginning that tells us the truth. How some supplements work for some people but don't work for others. Why companies don't need to rely on third-party studies anymore. [01:25:00] Geviti Can Save Your Life + Time How Geviti has helped people diagnose cancer and cardiovascular disease. Why Geviti saves us time compared to going to a doctor's office. The importance of designing products around mothers and busy entrepreneurs. [01:29:00] AI for Longevity Why in the future most people will live to be over 100. How AI will create abundance and make services more accessible. Why Geviti's costs have gone down since the rise of AI. [01:33:50] Heal Your Body with Stem Cells Why stem cell treatments are becoming more popular. Joy Kong MD How Geviti is developing a stem cell product from umbilical cords. Why MSC stem cells target what needs to be healed. How one stem cell IV saved a man's life whose liver was failing. Why peptides and stem cells are going to help us live longer. Leave Wellness + Wisdom a Review on Apple Podcasts Power Quotes From The Show Big Pharma Wants You Sick! "There's incentive to keep people sick because Big Pharmaceutical will profit off of it, and then they'll prescribe the medications and the medications to combat the side effects of their own medications. It's a vicious cycle that's very hard to escape." - Nathan Graville Peptides + MSCs "Peptides and MSCs are the future of longevity. These are two therapeutics that will get us to living into our hundreds. When you do a MSC IV, it's going to find out where in your body you need healing and it's going to go to those areas on its own. This is potentially the most powerful therapeutic that we know about in existence as it relates to longevity." - Nathan Graville Feeling Healthy Doesn't Equal Being Healthy "There's no way to know if you're healthy based on just how you feel. You can have elevated markers that are directly correlated to all-cause mortality. Which is why looking underneath the hood is so crucially important. The only way to know is by doing a routine blood work." - Nathan Graville Links From Today's Show Nathan Graville Geviti Conscious Capitalism by John Mackey + Raj Sisodia 734 Kirk Parsley MD | Sleep As Medicine: How To Sleep Like Royalty + Stop Being Sick 694 Shawn Wells | Your Ultimate Guide To Healing Mental + Physical Health NOOTOPIA (10% off with code JOSH10) Joy Kong MD Josh's Trusted Products | Up To 40% Off Shop All Products Biohacking MANNA Vitality - Save 20% with code JOSH20 HigherDOSE - 15% off with the code WELLNESSANDWISDOM PLUNGE - $150 off with discount code WELLNESSFORCE Pulsetto - Save 20% with code "JOSH" SaunaSpace - 10% off with discount code JOSH10 Ultrahuman Ring Air - 10% off with code JOSH NutriSense - 30% off with WELLNESSFORCE Wellness Test Kits Choose Joi - Save 50% on all Lab Tests with JOSH Blokes - Save 50% on all Lab Tests with JOSH FertilityWize Test by Clockwize - Save 10% with code JOSH Tiny Health Gut Tests - $20 off with discount code JOSH20 VIVOO Health Tests - Save 30% off with code JOSH SiPhox Health Blood Test - Save 15% off with code JOSH Nutrition + Gut Health Organifi - 20% off with discount code WELLNESSFORCE SEED Synbiotic - 25% off with the code 25JOSHTRENT Paleovalley - Save 15% off here! 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His commitment to building technology for positive impact is currently centered on increasing both healthspan and lifespan. He designs and builds products to enhance user experiences and improve lives, and is fueled by the desire to challenge the status quo and deliver meaningful change to the world. Nathan is driven by the prospect of bringing impactful projects to life and aims to create positive change on a global scale. Website Instagram Facebook YouTube
Inflammation has become a nutrition buzzword, often used in extreme or misleading ways. This episode aims to clarify what inflammation is, how it relates to diet and health, and whether specific foods truly provoke inflammatory responses in the body. The episode provides a nuanced, evidence-based look at inflammation and diet. It explains the difference between acute and chronic inflammation, outlines the role of chronic low-grade inflammation in disease, and emphasizes that overall dietary patterns – rather than any single food – are what influence our inflammatory status. Commonly demonized foods (such as sugar, wheat, and dairy) are scrutinized, and the conversation debunks myths about them being uniformly “inflammatory.” In this episode, Danny takes a look at what the scientific evidence actually shows about anti-inflammatory diets. Note: This is a Premium-exclusive episode. Timestamps 01:06 Understanding Inflammation: Basics and Biomarkers 04:02 Acute vs. Chronic Inflammation 14:21 Biomarkers of Inflammation 22:51 Dietary Patterns and Inflammation 34:53 Specific Foods and Nutrients Impacting Inflammation 47:01 Practical Takeaways for an Anti-Inflammatory Diet 51:30 Conclusion Related Resources Subscribe to Sigma Nutrition Premium Enroll in the next cohort of our Applied Nutrition Literacy course Related podcast episodes: 329: Diet & Inflammation 353: James Hébert, ScD – Dietary Inflammatory Index Sigma Statement: Nutrition & Immune Function The Dietary Inflammatory Index (DII) – Hébert et al., 2019
Synopsis: What happens when a world-class scientist and a philanthropic legacy collide with one of medicine's greatest challenges? Dr. Howard Fillit and Mark Roithmayr of the Alzheimer's Drug Discovery Foundation (ADDF) join host Alok Tayi for an inspiring conversation on bold science, visionary funding models, and the future of Alzheimer's research. From treating Estée Lauder in the 1990s to building a $100M venture philanthropy engine, they trace ADDF's evolution into a global leader in high-risk, high-reward drug development. The discussion covers the rise of biomarkers and digital diagnostics, the foundation's partnerships with visionaries like Bill Gates and Jeff Bezos, and how ADDF's venture philanthropy approach bridges the “valley of death” in biotech. They also dive into global regulatory challenges, the economic urgency of Alzheimer's, and why the future lies in prevention, precision medicine, and a patient-first mindset. This episode is a masterclass in scientific grit, ecosystem thinking, and turning urgency into progress. Biography: Howard Fillit, MD Founding Executive Director and Chief Science Officer of the Alzheimer's Drug Discovery Foundation Howard Fillit, MD, is a geriatrician, neuroscientist, and innovative philanthropy executive, who has led the Alzheimer's Drug Discovery Foundation (ADDF) since its founding. Dr. Fillit has held faculty positions at The Rockefeller University, the SUNY-Stony Brook School of Medicine and the Cornell University School of Medicine. In 1987, he joined the Mount Sinai School of Medicine, where he is a clinical professor of geriatric medicine and palliative care, medicine and neuroscience. Dr. Fillit also maintains a limited private practice in consultative geriatric medicine with a focus on Alzheimer's disease and related dementias. He has authored or co-authored more than 300 publications and is the senior editor of Brocklehurst's Textbook of Geriatric Medicine and Gerontology. Dr. Fillit is the recipient of many awards and honors including the Rita Hayworth Award from the Alzheimer's Association. Mark Roithmayr Chief Executive Officer Mark Roithmayr is an admired nonprofit leader with four decades of experience in both start-ups and mature organizations. As CEO of the ADDF, he is responsible for steering the Foundation's overall strategy, focus, and business operations. Since joining the ADDF in 2017, the organization has transformed dramatically in impact, scale, presence, and brand. Under his leadership, the ADDF's revenue has increased five-fold from $17M to over $90M, and mission-related investing has grown over 100%. He works closely with Dr. Fillit, executive leadership, and the board to advance the ADDF's mission of accelerating the discovery of drugs to prevent, treat, and cure Alzheimer's disease and related dementias. His key accomplishments include securing donations from Bill Gates, Jeff Bezos, and MacKenzie Scott, and a 10-figure gift from the Lauder family to cover ADDF's overhead for the next 20 years.
L'arrivée des beaux jours rime souvent avec barbecue. Mais derrière ce plaisir convivial se cachent des risques pour la santé, bien documentés par la recherche médicale.Le principal danger réside dans la formation de composés chimiques toxiques lors de la cuisson à haute température. Lorsque les graisses de la viande fondent et tombent sur les braises, elles génèrent de la fumée. Cette fumée contient des hydrocarbures aromatiques polycycliques (HAP), substances classées cancérogènes probables par le Centre International de Recherche sur le Cancer (CIRC). Ces HAP se déposent ensuite sur les aliments.De plus, la cuisson de la viande à des températures élevées entraîne la formation de amines hétérocycliques (AHC). Ces molécules se créent lors de la réaction entre les acides aminés et les sucres présents dans la viande. Elles sont elles aussi considérées comme cancérogènes.Mais ce n'est pas qu'une théorie. Une étude majeure publiée en 2005 dans la revue Cancer Epidemiology, Biomarkers & Prevention par le Dr Kristin Anderson, épidémiologiste à l'université du Minnesota, a suivi plus de 62 000 femmes. Résultat : celles qui consommaient régulièrement de la viande bien cuite au barbecue avaient un risque de cancer du sein augmenté de 54 % par rapport aux femmes qui en consommaient peu ou pas.Les risques concernent aussi d'autres cancers : colorectal, pancréas, prostate… Plusieurs études épidémiologiques ont montré une corrélation entre une consommation fréquente de viande grillée et une augmentation de ces cancers.Autre point préoccupant : les HAP ne se contentent pas d'augmenter le risque de cancer. Ils peuvent aussi avoir des effets sur le système cardiovasculaire et entraîner des inflammations chroniques. Quant aux AHC, ils peuvent endommager l'ADN des cellules, un mécanisme clé dans le développement tumoral.Faut-il pour autant bannir le barbecue ? Pas nécessairement. Il est possible de réduire ces risques en adoptant quelques précautions :éviter de carboniser les aliments,cuire à une température plus modérée,mariner la viande, ce qui réduit la formation d'AHC,privilégier les légumes grillés, beaucoup moins concernés par ces composés toxiques.En résumé, la cuisson au barbecue expose à des substances cancérogènes connues. La recherche médicale, comme l'étude de l'université du Minnesota, démontre que leur consommation répétée augmente significativement le risque de cancer. En adaptant ses pratiques, on peut cependant continuer à profiter de ces moments en limitant les dangers. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Have you heard of longevity medicine? It's next-level healthcare—and Dr. Darshan Shah is one of the pioneers leading the way. In this episode, Dr. Shah shares how he's transforming the way we treat women in perimenopause and postmenopause by focusing on real root causes—not just symptom management. We cover: What he learned about women's health as a surgeon How he approaches menopause differently than most doctors The truth about hormone testing during the transition The real drivers of Alzheimer's, osteoporosis, and heart disease in women Why so many doctors are confused about menopause care Exactly how to empower yourself at your first menopause visit How he uses the Wellness Wheel to individualize care A peek into cutting-edge therapies like Therapeutic Plasma Exchange and NAD+ Darshan Shah, MD, is a health and wellness specialist, board-certified surgeon, published author, entrepreneur, and founder of Next Health, the first, largest and fastest-growing health optimization and longevity clinic. He began his career at an accelerated MD program and earned his medical degree at the age of 21, becoming one of the youngest doctors in the United States. He then continued his training at the Mayo Clinic, and earned his MBA from Harvard Business School in 2015. As a longevity medicine specialist, he has advised thousands of patients on how to optimize their well-being and extend their healthspan and lifespan. PREVIOUS EPISODE: https://www.drshah.com/extend-podcasts/zora-benhamou Extend Podcast: https://podcasts.apple.com/us/podcast/welcome-to-extend-with-darshan-shah-md/id1773578243?i=1000673875409 Biomarkers list: https://www.drshah.com/biomarkers Contact Dr. Darshan Shah Website: https://www.next-health.com/ Instagram: https://www.instagram.com/darshanshahmd Email: contact@drshah.com Give thanks to our sponsors: Qualia senolytics and brain supplements. 15% off with code ZORA here. Try Vitali skincare. 20% off with code ZORA here https://vitaliskincare.com Get Primeadine spermidine by Oxford Healthspan. 15% discount with code ZORA here. Get Mitopure Urolithin A by Timeline. 10% discount with code ZORA at https://timeline.com/zora Try Suji to improve muscle 10% off with code ZORA at TrySuji.com https://trysuji.com Get Magnesium Breakthrough by Bioptimizers. 10% discount with code HACKMYAGE at https://bioptimizers.com/hackmyage Try OneSkin skincare with code ZORA for 15% off https://shareasale.com/r.cfm?b=2685556&u=4476154&m=102446&urllink=&afftrack= Join Biohacking Menopause before July 1, 2025 to win free Vitali Skincare! 20% off with code ZORA at VitaliSkincare.com Join the Hack My Age community on: Facebook Page: @Hack My Age Facebook Group: @Biohacking Menopause Private Women's Only Support Group: https://hackmyage.com/biohacking-menopause-membership/ Instagram: @HackMyAge Website: HackMyAge.com
High blood biomarkers for Alzheimer's disease found by the newly FDA approved blood test indicate the presence of two proteins in the brain called amyloid and tau. Abhay Moghakar, a neurologist and blood biomarkers expert at Johns Hopkins, says some … What are current studies doing when high levels of blood biomarkers for Alzheimer's are found? Elizabeth Tracey reports Read More »
Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]
Experts discuss recent advances in how maternal health and immune function during pregnancy affect infant development and long-term outcomes. Research focuses on immune adaptations, complications like preterm birth, and neuroimmune pathways, using techniques such as mass cytometry, spatial proteomics, and chemogenetics to identify biomarkers and mechanisms that guide prevention and treatment strategies. Sandy Ramos, M.D. Clinical Landscape and OGRS Opportunities Louise Laurent, M.D.,Ph.D. Single-Cell and Spatial Multi-Omic Insights into the Human Placenta (HUBMAP) Marni Jacobs, Ph.D. The MOM-Health Study and the MOHD Consortium Lars Bode, Ph.D. Human Milk Institute (HMI) Gretchen Bandoli, Ph.D. MotherToBaby Ina Stelzer, Ph.D. Reproductive Immunology Series: "Motherhood Channel" [Health and Medicine] [Show ID: 40666]
In this episode, Dr Vignesh Devraj explores the profound Ayurvedic definition of health from the Sushruta Samhita and offers a fascinating correlation between these ancient principles and modern physiological biomarkers. Through a line-by-line breakdown of the classic Ayurvedic sutra, he explains how true health transcends physical fitness and encompasses harmony at the levels of body, mind, and spirit, providing a deep yet accessible exploration of what it truly means to be healthy, from both traditional and scientific perspectives. Episode Highlights:The Sanskrit meaning and layers of the Ayurvedic definition of healthWhy happiness is not the result of health, but a component of itHow to assess Vata, Pitta, and Kapha through BiomarkersUnderstanding Samadhatu and why it mattersAgni, metabolism, and weight managementMind-body harmony for lasting health Timestamps:00:00 - 02:00: Definition of health in Sushruta Samhita02:00 - 03:00: Health and Happiness03:00 - 07:30: Biomarkers that signal Dosha Imbalance07:30 - 10:00: Understanding Samadhatu10:00 - 12:30: Weight Loss, Fertility, and Overall Health12:30 - 15:24: Sleep, Stress, and EnduranceIf you are interested in doing one on one Ayurvedic consultation with Dr Vignesh Devraj, please find the details in this link: https://calendly.com/drvignesh/30-minute-session-with-dr-vignesh-devraj-md-ay-istIf you are economically challenged, please use the form provided to request a free Ayurvedic consultation here. (or copy paste this in your browser: https://docs.google.com/forms/d/e/1FAIpQLSd29nHcrC1RssR-6WAqWCWQWKKJo7nGcEm8ITEl2-ErcnfVEg/viewform )BALANCE THE MIGHTY VATA - ONLINE COURSE NOW AVAILABLE What makes Ayurveda unique in its treatment approach is its practical wisdom on the concept of Vata. Vata is responsible for Prana - the life energy, nervous system - the master panel of our body, and our emotions. In Ayurveda, it is mentioned that controlling Vata is the most difficult part of healing and recovery. Recently, I have recorded a workshop on - Balancing The Mighty Vata which has over 6 hrs of content, with notes filled with practical inputs that can be integrated into our life. You can access this at https://drvignesh.teachable.com/For further information about Dr Vignesh Devraj, kindly visit www.vigneshdevraj.com and www.sitaramretreat.com Instagram - @sitarambeachretreat | @vigneshdevrajTwitter - @VigneshDevrajWe truly hope you are enjoying our content. Want to help us shape and grow this show faster? Leave your review and subscribe to the podcast, so you'll never miss out on any new episodes. Thanks for your support.Disclaimer: - The content of the podcast episodes is not intended to be a substitute for professional medical procedures, consultations, diagnosis, or treatment in any manner. We strongly do not recommend using the content of these episodes as medical advice for any medical conditions for you, others, or for treating your patients
AGNTCY - Unlock agents at scale with an open Internet of Agents. Visit https://agntcy.org/ and add your support. What if your blood could reveal the future of your health - years before symptoms ever appear? In this episode of Eye on AI, Craig Smith sits down with Ash Anwar, co-founder of Molecular You, to explore how AI and advanced biomarker analysis are transforming how we detect and prevent disease. From a real-life case where stage 1 pancreatic cancer was caught early, to the science behind tracking 250+ dynamic biomarkers, Ash breaks down how Molecular You is shifting healthcare from reactive treatment to proactive longevity. They dive into the limitations of genetic testing, the power of machine learning models trained on clinical data, and how personalized action plans are helping individuals take control of their health in real time. If you're curious about the intersection of AI, diagnostics, and the future of preventive medicine—this is a conversation you won't want to miss. Stay Updated: Craig Smith on X: https://x.com/craigss Eye on A.I. on X: https://x.com/EyeOn_AI (00:00) How AI Can Predict Disease Before It Happens (02:02) Meet Ash Anwar: From Scientist to Health Tech Leader (06:31) What Is Molecular You and How It Works (09:43) Why Biomarker Tracking Over Time Is a Game-Changer (15:46) How Molecular You Detected Stage 1 Pancreatic Cancer (23:15) Biomarkers vs Genetics: What Really Matters (28:11) The AI Models Behind Early Disease Detection (32:37) How the Product Works for Clinics and Consumers (35:05) Who They Compete With and What Makes Them Different (37:34) Research vs Product: The Cancer Risk Challenge (43:43) How Often Should You Get Tested?
This week on Health Matters we reflect on the top health tips and takeaways from our May series dedicated to Women's Health Month. Courtney is joined by Angelique Serrano to talk more about how to care for our skin, bone, and brain health, as well as ways to recognize and manage perimenopause symptoms. In their conversations with Health Matters, neurologist Dr. Sonja Blum and dermatologist Dr. Shari Lipner shared small daily habits that can make big contributions to long term health. Dr. Mary Rosser, an OB-GYN, shares a process for tackling sleep issues during perimenopause. Physiatrist Dr. Erica Eldon explains the importance of bone strength and how to prevent ailments like a broken hip. Courtney and Angelique share how the advice from NewYork-Presbyterian doctors opens space for women to discuss health care decisions in ways that are often overlooked and how they are inspired to prioritize their own health.___Health Matters shares stories of science, care, and wellness from NewYork-Presbyterian, one of the nation's most comprehensive healthcare systems.NewYork-Presbyterian's Health Matters features the latest news and insights from our world-class physicians, nurses, and experts; inspiring first-hand accounts from patients and caregivers; and updates on the latest research and innovations in patient care, all in collaboration with our academic partners Columbia and Weill Cornell Medicine.To learn more visit: https://healthmatters.nyp.org/
David McDermott joins us on the heels of his outstanding discussion of the clinical science symposium on RCC biomarkers.
Levels offers biomarker testing to give you more insight into your health status so you can understand the root causes of your symptoms, take a preventive approach to disease, and see if your lifestyle changes or other interventions are reducing your risk factors and improving your health. Dr. Anjali Dsouza and Mike Haney discuss why biomarker testing can be beneficial, how to understand your levels, factors that affect your levels, and which biomarkers are no-brainers to get tested.Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnlLevels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.