Podcasts about biomarkers

Dr. Kevin Ko on Biomarkers, Oral Dysplasia, and the Limits of H&E DiagnosisChristine interviews Dr. Kevin Ko (DMD, MD), a pathologist at the BC Cancer Agency with training in oral and maxillofacial pathology, anatomic pathology, and dermatopathology. They discuss his ASDP 2025 lecture on using p53 in oral dysplasia as a potential new approach and the broader problem of diagnostic discordance and over-diagnosis when relying on H&E alone. Dr. Ko shares examples from practice, including recognizing oral porokeratosis (previously followed as dysplasia for years) and a chemotherapy-related lip lesion initially suspected to be severe dysplasia but supported by wild-type biomarker results and clinical history, resolving after stopping chemotherapy drugs. He emphasizes the need for reproducible biomarkers and possibly molecular-based classification to improve consistency and patient outcomes, while also describing the pressure to be near-perfect in pathology, the risk of burnout, and efforts to build sustainable systems (QA sessions, colleague consultation, protected time). The conversation closes with his approach to presentations as storytelling, interest in prospective multi-center research, and a final message about balancing perfectionism with rest while remaining open-minded to new diagnostic methods to improve patient care.00:00 Welcome & Meet Dr. Kevin Ko (DMD/MD, Dermpath at BC Cancer)01:00 The Controversial Idea: Using p53 Biomarkers in Oral Dysplasia01:18 Oral vs Skin Pathology: Discovering Porokeratosis in the Mouth02:07 Diagnostic Error & Overdiagnosis: Why Reproducible Biomarkers Matter05:19 Case Study: “Severe Dysplasia” vs Toxic Erythema of Chemotherapy —Context Changes Everything06:36 The Perfectionism Trap in Pathology (and Why 95% Isn't Good Enough)08:04 Burnout, QA Systems, and Building Sustainable Workflows09:14 Work–Life Balance, Kids, and Choosing Priorities (Family vs Research)11:14 How to Build a Great Talk: Storytelling, Cases, and Future Studies11:38 Final Takeaways: Balance, Open-Mindedness, and Better Diagnostics

The surgeon who spent 12 to14 hours a day in the operating room developed diabetes, uncontrolled high blood pressure, and an autoimmune disease that was eating away at his skull and it forced him to confront what medical school never taught him about actually staying healthy. I sat down with Dr. Darshan Shah, board-certified surgeon, founder of Next Health (one of the largest longevity clinic networks in America), and a doctor who had to reverse his own chronic disease to understand the massive gap between Western medicine and the science of health. We explore why surgeons and physicians become some of the sickest people in healthcare, how functional medicine differs from what you learn in medical school, why biomarker testing matters more than your doctor's "you're fine" assessment, and what root cause medicine actually looks like in practice. Dr. Shah also breaks down the AI revolution happening in cardiovascular imaging with Cleerly scans, how his new AI health dashboard reads your bloodwork and medical records to give you proactive guidance, why Yamanaka factors could regenerate damaged nerves in the brain, and what the future of personalized, preventive medicine looks like when you combine AI with real biological data. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+: https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The surgeon who developed the diseases he was treating 01:17 From trauma surgeon to longevity doctor: Dr. Shah's journey 04:18 Autoimmune disease, diabetes, and high blood pressure in a surgeon 10:30 Western medicine vs. the science of health 18:45 Why doctors don't learn prevention in medical school 35:20 Next Health clinics and democratizing longevity medicine 52:40 Biomarker testing and why "your labs are normal" is dangerous 01:03:52 AI health dashboard: uploading bloodwork and getting proactive guidance 01:06:45 Cleerly scans and reversing cardiovascular disease with AI imaging 01:10:08 Yamanaka factors, nerve regeneration, and the future of brain health _______ Thank you to our sponsors Function Health: https://www.functionhealth.com/louisanicola Timeline Mitopure: http://timeline.com/NEURO Ka'Chava: https://kachava.com and use code NEURO for 15% off your first order Wayfair: https://www.wayfair.com/ Fenix: https://www.fenixhealthscience.com/ Arey: https://arey.com/ and use code NEURO _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups.For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/SHS865. CME/MOC/NCPD/AAPA/IPCE credit will be available until February 28, 2027.Preparing for the New Era of Blood-Based Biomarkers in Alzheimer's Disease: Navigating Guidelines, Understanding Policy, and Integrating Into Practice Workflows In support of improving patient care, PVI, PeerView Institute for Medical Education, is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.SupportThis activity is supported by an educational grant from Lilly.Disclosure information is available at the beginning of the video presentation.

Despite major advances in our understanding of the biology of mental health disorders,  there's no blood test or brain scan that will confirm if you have depression, anxiety, PTSD, or any other psychiatric illness.  And yet, the American Psychiatric Association recently announced that it will be including biomarkers for mental conditions in the next edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM), which guides diagnosis and treatment of mental illness. So how close are we to pinpointing the biological markers of mental illness, and what does that mean for diagnosis? It's complicated.  Host Flora Lichtman untangles some of this science with psychiatry researcher John Krystal. Guest: Dr. John Krystal is a professor of psychiatry, neuroscience, and psychology at the Yale School of Medicine. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Send a textIs AI in pathology actually improving diagnosis — or just adding complexity?In DigiPath Digest #37, we reviewed four recent publications covering AI-based biomarker quantification in glioblastoma, real-world digital workflow integration in prostate cancer, multimodal AI combining histopathology and genomics, and patient perspectives on AI in cancer diagnostics.This episode connects technical performance with something equally important: trust.Episode Highlights[00:02] Community & updates Digital Pathology 101 free PDF, upcoming patient-focused book, and global attendance.[04:07] AI-based image analysis in glioblastoma AI showed strong consistency with pathologists when quantifying Ki-67, P53, and PHH3. Significant biological correlations (Ki-67 ↔ PHH3, PHH3 ↔ P53) were detected by AI — not by manual assessment. Takeaway: computational quantification improves precision.[09:28] Real-world digital workflow + AI in prostate cancer (France) AI-pathologist concordance: • 93.2% (high probability cancer detection) • 99.0% (low probability slides) Gleason concordance: 76.6% 10% failure rate due to pre-analytical artifacts. Takeaway: infrastructure and sample quality still matter.[15:58] Multimodal AI (MARBIX framework) Combines whole slide images + immunogenomic data in a shared latent space using binary “monograms.” Performance in lung cancer: 85–89% vs 69–76% unimodal models. Takeaway: integrated data improves case retrieval and similarity reasoning.[22:13] AI-powered paper summary subscription introduced Structured summaries for busy professionals who want more than abstracts.[26:17] Patient roundtable on AI in pathology (Belgium) Patients expect: • Better accuracy • Faster turnaround • Stronger collaborationTrust is high when: • Algorithms use diverse datasets • Pathologists retain final responsibilityClinical validity mattered more than full algorithm transparency. Privacy concerns focused more on insurer misuse than cloud transfer.Key TakeawaysAI improves biomarker precision in glioblastoma.Digital pathology implementation works — but pre-analytics can limit AI performance.Multimodal AI represents the next meaningful step in precision diagnostics.Patients are not afraid of AI — they want validation, oversight, and governance.Human–AI collaboration remains central.If you're working in digital pathology, computational pathology, or precision oncology, this episode connects evidence, implementation, and patient perspective.Support the showGet the "Digital Pathology 101" FREE E-book and join us!

Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice.In this Mind Moments episode, Jeff Chamberlain, PhD, joins the podcast during Duchenne Muscular Dystrophy Awareness Week to provide clinical and translational perspective on the evolving landscape of DMD biology and therapy. Chamberlain, professor at the University of Washington School of Medicine and Director of the Senator Paul D. Wellstone Muscular Dystrophy Cooperative Research Center in Seattle, reflects on aspects of Duchenne pathophysiology that may still be underappreciated, including evidence that disease processes begin earlier than once recognized and the growing importance of immunologic factors in shaping progression and therapeutic response. The conversation also explores how neuromuscular specialists should approach treatment timing and combination strategies as gene-targeted therapies expand, the evolving interpretation and limitations of biomarkers such as creatine kinase and dystrophin expression, and what emerging gene therapy platforms may signal for care heading into 2026 and beyond.Looking for more Neuromuscular discussion? Check out the NeurologyLive® Neuromuscular clinical focus page.Episode Breakdown: 1:15 – Underrecognized aspects of DMD pathophysiology, including early onset and immunologic drivers 4:50 – Treatment timing, sequencing, and the rationale for combination strategies 8:00 – Neurology News Minute 10:30 – Clinical trial and real-world implications of dystrophin and CK as biomarkers 16:20 – Anticipated gene therapy innovation and safety considerations heading into 2026 The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: Regenxbio's MPS II Gene Therapy RGX-121 Hit With CRL FDA Accepts New Drug Application for Orexin Agonist Oveporexton in Narcolepsy Type 1, Grants Priority Review FDA Expands Indication for Pitolisant to Treat Cataplexy in Pediatric Narcolepsy Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.

Molly McVoy, MD, dives into the mental health crisis affecting teens, why anxiety and depression have risen dramatically, and shares breakthrough research using EEG biomarkers and self-management programs that help teens build resilience. Learn more about Daniel Simon, MDLearn more about Molly McVoy, MDNEW! View our Science@UH video podcast on YouTubeLearn more about the University Hospitals Research & Education Institute

Guest: Adil Harroud, MD Guest: Dylan Hamitouche Host: Ryan Quigley Multimodal aging signatures are reshaping our understanding of progression and prognosis in multiple sclerosis (MS). Host Ryan Quigley sits down with Dr. Adil Harroud and Mr. Dylan Hamitouche to learn more about implications for the future of risk stratification and personalized treatment in MS, a topic they presented on at the 2026 ACTRIMS Forum. Dr. Harroud is a neurologist and the co-leader of the Neuroimmunology Diseases Research Group at the Montreal Neurological Institute at McGill University. Mr. Hamitouche is a medical student at McGill University.

Guest: Raphael Schneider, MD, PhD, FRCPC, CIP Multiplex proteomic biomarker panels are redefining how we understand and monitor multiple sclerosis (MS) by capturing interconnected pathways in a single sample. Hear from Dr. Raphael Schneider as he explores how these tools could inform prognosis, risk stratification, and clinical trial design, which he spoke about at the 2026 ACTRIMS Forum. Dr. Schneider is a neurologist and researcher at the BARLO MS Centre at St. Michael's Hospital as well as an Assistant Professor and the Elizabeth S. Barford Early Career Professor in Multiple Sclerosis in the Department of Medicine at the University of Toronto.

Guest: Raphael Schneider, MD, PhD, FRCPC, CIP Multiplex proteomic biomarker panels are redefining how we understand and monitor multiple sclerosis (MS) by capturing interconnected pathways in a single sample. Hear from Dr. Raphael Schneider as he explores how these tools could inform prognosis, risk stratification, and clinical trial design, which he spoke about at the 2026 ACTRIMS Forum. Dr. Schneider is a neurologist and researcher at the BARLO MS Centre at St. Michael's Hospital as well as an Assistant Professor and the Elizabeth S. Barford Early Career Professor in Multiple Sclerosis in the Department of Medicine at the University of Toronto.

Guest: Adil Harroud, MD Guest: Dylan Hamitouche Host: Ryan Quigley Multimodal aging signatures are reshaping our understanding of progression and prognosis in multiple sclerosis (MS). Host Ryan Quigley sits down with Dr. Adil Harroud and Mr. Dylan Hamitouche to learn more about implications for the future of risk stratification and personalized treatment in MS, a topic they presented on at the 2026 ACTRIMS Forum. Dr. Harroud is a neurologist and the co-leader of the Neuroimmunology Diseases Research Group at the Montreal Neurological Institute at McGill University. Mr. Hamitouche is a medical student at McGill University.

Send a textJoin us for a special Kidney Cancer treat!!!A Must Listen episode!!We discuss the role of biomarkers in advanced kidney cancer with the wonderful Professor Laurence Albiges from the Gustave Roussy Institute of Oncology in Paris.No Kidney Cancer talk is complete without the question -" Where are we with biomarkers?"This is part 1 of a 2 part walkthrough of the biomarker story so far in kidney cancer.Laurence is unequalled in her clear delivery on this subject.As lead for the CARE-1 study Laurence is examining the role of PDL1 as a biomarker in 1st line treatment of mRCC.We also discuss the;- IMDC criteria- Clusters- KIM-1- PDL1- Sarcomatoid featuresRecorded before Christmas this is a gift that keeps on giving.We hope you enjoy!!Check the Transcript for more details.

By David Stephen who looks at biomarkers in this article. Will there ever be a biological test for human intelligence, to explore how to improve it in the age of AI? Like, would it ever be possible to test a human being for intelligence by some biological factor, and how to make it competitive against AI? The same question applies to mental disorders. Would there ever be biological tests, to know what therapies would work? These, at least for mental disorders, is what the American Psychiatric Association is seeking. Biomarkers for Psychiatry, Human Intelligence There is a recent [January 28, 2026] press release, APA Releases Roadmap for the Future of the DSM, stating that, "The American Psychiatric Association (APA) has released a series of papers offering a proposed roadmap for the future of the Diagnostic and Statistical Manual of Mental Disorders (DSM). The five papers, including the Initial Strategy for the Future of the DSM and four accompanying commentaries, are the result of the committee's year of structured debate and consideration of long-standing critiques and rapid scientific advances. They propose a forward-looking model for the evolution of the DSM. They also suggest changing the name from Diagnostic and Statistical Manual to Diagnostic and Scientific Manual to better reflect its scientific and global scope. The four accompanying papers address structure and dimensions of the DSM; the role of biomarkers and biological factors in diagnosis; vision for incorporating socioeconomic, cultural and environmental determinants of health and intersectionality; and the role of functioning and quality of life in psychiatric diagnosis." Conceptual Biomarkers and Theoretical Biological Factors for Psychiatric and Intelligence Nosology What are the options for biomarkers in the brain for mental disorders? Would they be different or similar to those for human intelligence? What are the universal components in the brain, for functions of human life and experiences? Can a model be developed on these components and their mechanisms, first to explain labels and next to scope out biomarkers? The problem before psychiatry is not just the distance to developing tests but to even describe what is happening in the brain for the labels of conditions. Mood disorders have several descriptions. But what are their components in the brain and the course of their actions. Answering these questions can put conditions in perspective as parallels are sought, before adventuring into biomarkers development. The same applies to human intelligence. Now, artificial intelligence is in an intense acceleration. There are valuable labor tasks that will be lost due to AI. And, because intelligence is the last frontier of superiority for humanity among organisms, it will be important to seek to map it, and explore it for problem-solving. This is the postulation in Conceptual Biomarkers and Theoretical Biological Factors for Psychiatric and Intelligence Nosology. The options are electrical and chemical signals as the components of functions in the brain. It states that neurons are conduits or bridges that signals use to carry out functions. It also states that signals are in sets in cluster of neurons. It is possible to use signals, conceptually, to explain and display all disorders in the DSM. It is also possible to use them to develop, explain, and display the two main types of human intelligence [improvement and operational], to ensure that options are broadened towards survival in the age of AI. This seminal work on conceptual brain science could be completed by August, 2026, moving psychiatry and intelligence forward, as well as neurology. David Stephen currently does research in conceptual brain science with focus on the electrical and chemical configurators for how they mechanize the human mind with implications for mental health, disorders, neurotechnology, consciousness, learning, artificial intelligence and nurture. He was a visiting scholar in m...

What if the way you age isn't just about time and genetics—but about your beliefs? What if your face, your energy, your vitality are shaped not only by biology but by what we might call your belief biology? In this episode, Harmony Slater sits down with Angelika Anagnostou, a practitioner of the Life Alignment methodology, to explore a radically different perspective on rejuvenation—one that blends the science of consciousness with the body's innate intelligence.   Disclaimer: The information shared in this episode is for educational and entertainment purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. The views and experiences expressed by the host and guest reflect their personal perspectives and practices and should not be interpreted as medical claims. Always consult a qualified healthcare provider before making changes to your health routine or discontinuing any medical treatment. Neither Finding Harmony Podcast, its host, guest, nor production team assume any responsibility or liability for any actions taken based on the content of this episode.   IN THIS EPISODE: What “belief biology” means and how your thoughts directly shape how you age The science of biophotons: how your cells literally emit light—and how your emotional state changes that light Why your body is your most faithful servant and responds to every instruction you give it The morphogenetic field: the collective agreement about aging that most of us unconsciously follow Ellen Langer's “Clockwise” study: how elderly participants reversed biological markers of aging How emotions get stored in the face and body—and how to release them The difference between fighting aging and reconnecting with your original energetic blueprint Why presence and the power of the present moment are the keys to rejuvenation Harmony's personal story of healing her eyesight without surgery Practical steps you can start today: observing the thoughts you direct toward your body How the Life Alignment method creates a meditative space for reprogramming the body The seven codes for rejuvenation and radiance (preview)   Chapters 00:00 Welcome to Finding Harmony: Ancient Wisdom Meets Modern Life 00:42 Belief Biology: Rethinking Aging, Beauty & Vitality 04:04 Meet Angelica: Why Rejuvenation Starts From Within 07:20 The Age ‘Download': How Birthdays Trigger Beliefs in the Body 09:53 Mantras, Biomarkers & the Body Listening to Your Commands 13:37 Stress, Presence & Life Force: The Fast Track to Looking Younger 16:11 Biophotons and Inner Light: The Science Behind Radiance 18:34 Life Alignment Method: Quiet the Mind, Reprogram the Body 20:13 Your Original Blueprint: Sacred Geometry, Energy Codes & Choosing Your Form 22:33 Consistency Creates Change: Building a New Identity Beyond Old Conditioning 25:36 Where Science Is Pointing: Quantum Physics and the Future of Healing 26:45 Biohacking vs Mind: The Energy Field Behind Healing 27:15 Ellen Langer's ‘Clockwise' Study: Reversing Aging Through Context 29:00 DNA, Entanglement & the ‘Biology of Belief' Explained 30:07 The Aging Script: How Midlife Retraction Programs the Body 31:37 Cancel the ‘Shut Down' Narrative: Watch Your Self-Talk 32:36 Field Consciousness & Radical Healing Stories (Organs, Skin, Vitality) 34:20 Beyond Genetics: You're the Engineer of Your DNA & Patterns 35:32 What to Expect in the Masterclass: Emotions in the Face + ‘Spiritual Botox' 37:18 How the Group Chooses the Focus Area + Spinal Energetics Recalibration 39:30 Dates, Details & One Practice to Start Now: Catch the Thought Loop 42:05 Mirror Work & Playfulness: Reprogramming Beauty Beliefs (Salma Example) 44:24 Final Invitation + Podcast Wrap: Where Rejuvenation Really Begins   GUEST BIO: Angelika Anagnostou is a practitioner of the Life Alignment methodology who helps people reconnect with their innate intelligence and energetic blueprint. Her work focuses on using consciousness, energy, and direct experience to facilitate deep healing, rejuvenation, and personal transformation.   Find Angelika on IG: https://www.instagram.com/living.alchemy Find Angelika online: http://www.iamwellness.in   SPECIAL OFFER: Join Harmony and Angelika for the Inner Rejuvenation Codes masterclasses: February 21 and March 7, 2026. Plus a 6-week program launching at the end of March 2026. https://harmonyslater.kit.com/inner-rejuvenation-codes-mc FIND Harmony online: https://harmonyslater.com/ Harmony on IG: https://www.instagram.com/harmonyslaterofficial/ Finding Harmony Podcast on IG: https://www.instagram.com/findingharmonypodcast/ FREE Manifestation Activation: https://harmonyslater.kit.com/manifestation-activation

Think your brain has to slow down with age? We push back hard with science, stories, and a step-by-step plan that has helped patients regain clarity in weeks, not years. Our guest, Dr Majid Fotuhi, a Harvard- and Hopkins-trained neurologist who has treated thousands of patients, explains why common forgetfulness isn't the same as cognitive decline and how simple daily choices can restore sharpness at any age.We break brain health down to four core levers: increase blood flow, reduce inflammation, enhance the brain's cleaning systems, and minimize plaques and tangles. Then we map those levers to five daily pillars you can actually do: exercise, sleep, nutrition, stress reduction, and learning. You'll hear why exercise is the highest-yield habit for cognition, how BDNF acts like fertilizer for the hippocampus, and what happens when sugar spikes and insulin resistance quietly shrink your memory center. We also get practical about sustainable nutrition, from curbing glucose swings to deciding whether keto is worth it for your lifestyle.Beyond biology, we dig into the mindsets that keep the brain young. Boredom—of the unplugged, daydreaming kind—can unlock creativity and problem solving. A clear sense of purpose measurably lowers dementia and stroke risk while making healthy choices easier to keep. We share the telltale red flags (like repeating questions) versus normal lapses (like misplacing keys), plus the personalized assessment approach that uncovered treatable factors in patients who feared Alzheimer's. If you want a realistic timeline, expect noticeable gains in about 12 weeks when you dial in the five pillars.Ready to build a resilient, younger brain? Follow the five pillars, personalize your plan, and start today with one small step—take a brisk walk, protect your sleep window, or learn something challenging you actually enjoy. If this conversation helped you, tap follow, share it with a friend who needs hope, and leave a quick review so more people can find it.https://drfotuhi.com/Continue this conversation on SubStack: https://robertlufkinmd.substack.com Get 120 Biomarkers for $99 and CT Calcium scans anywhere in the US. https://www.vitalsvault.com/ Win a Signed Copy of Lies I Taught in Medical School :https://robert-lufkin.mykajabi.com/pages/review-kit Web: https://robertlufkinmd.com/X: https://x.com/robertlufkinmdYoutube: https://www.youtube.com/robertLufkinmd Instagram: https://www.instagram.com/robertlufkinmd/LinkedIn: https://www.linkedin.com/in/robertlufkinmd/TikTok: https://www.tiktok.com/@robertlufkinThreads: https://www.threads.net/@robertlufkinmdFacebook: https://www.facebook.com/robertlufkinmd ...

In Episode 126 Joe speaks with Sue Peschin, President and CEO of the Alliance for Aging Research, about what Alzheimer's and dementia look like in the real world and how policy determines who gets help and when.  Sue explains the mission and 40–year history of the Alliance for Aging Research and lays out the scope of the Alzheimer's crisis in plain language: who is affected, how dementia types differ, and why neuropsychiatric symptoms like agitation, psychosis, and depression are so often ignored in policy and practice. They discuss why early detection matters more than ever now that disease-modifying therapies and amyloid inhibitors exist, and why so many cases are still missed in primary care. Sue walks through new blood biomarkers, digital cognitive assessments, and how Medicare coverage, CED restrictions, and the proposed ASAP Act will shape access to testing and treatment. Joe and Sue also dig into Coverage with Evidence Development (CED) in Medicare, whether CMS is overstepping what Congress intended under Section 1801, and how restrictive coverage decisions have limited access to Alzheimer's drugs to a tiny fraction of eligible patients. Finally, they talk about caregiver burden, stigma around behavioral symptoms, and what families and clinicians can realistically do today. If you care about Alzheimer's, dementia, early detection, blood biomarkers, Medicare coverage, CED, the ASAP Act, primary care, caregiver burden, vascular dementia, and aging research, this episode connects the science with the politics and the lived experience. In This ConversationJoe and Sue cover: What the Alliance for Aging Research is and why it focuses on “gap” aging and brain health issues How many Americans are living with Alzheimer's and dementia, including younger-onset cases The difference between Alzheimer's, vascular dementia, and other dementias, and why neuropsychiatric symptoms matter Why early and accurate detection is critical, even before someone qualifies for a disease-modifying therapy New tools: blood-based biomarkers, digital assessments, PET scans, and when they are used How Medicare coverage, Coverage with Evidence Development (CED), and the ASAP Act affect access to diagnostics and treatments The tension between FDA's role on safety and effectiveness and CMS's role on cost control and coverage Timestamps (Audio platforms) 0:00 Intro and Sue's background / Alliance for Aging Research 5:30 How big is the Alzheimer's and dementia problem 10:30 Why early detection matters and why diagnoses are still missed 18:30 Neuropsychiatric symptoms, stigma, and caregiver burden 26:30 Blood biomarkers, digital tools, and primary care 33:30 The ASAP Act and Medicare coverage for biomarkers 38:30 Coverage with Evidence Development (CED) and Section 1801 45:00 How to get involved and where to find resources Key Takeaways Alzheimer's is one of several dementias, and many patients have mixed dementia (Alzheimer's plus vascular changes). Early detection is vital, not only for disease-modifying therapies, but to rule out other treatable causes and to help families plan. New blood biomarkers and digital assessments could make detection cheaper and easier, but coverage and adoption lag behind the science. Medicare's CED policy has sharply limited access to Alzheimer's therapies despite FDA approval and labeled indications. The ASAP Act aims to secure Medicare coverage for Alzheimer's blood-based biomarkers without waiting on slow guideline processes. About Our GuestSue Peschin is President and CEO of the Alliance for Aging Research, the leading nonprofit focused on advancing science, policy, and education to improve healthy aging and access to care. At the Alliance, Sue has driven national work on Alzheimer's, dementia, neuropsychiatric symptoms, Medicare policy, CED reform, and aging research, empowering older adults and caregivers to advocate for better care.

Dr. Greg Cooper and Dr. David G. Coughlin discuss the role of αSyn-SAAs in diagnosing DBL and their relationship with Alzheimer's disease biomarkers.  Show citation: Coughlin DG, Jain L, Khrestian M, et al. CSF α-Synuclein Seed Amplification Assays and Alzheimer Disease Biomarkers in Dementia With Lewy Bodies: Presentation and Progression. Neurology. 2025;105(12):e214346. doi:10.1212/WNL.0000000000214346 Show transcript:  Dr. Greg Cooper: Hi, this is Dr. Greg Cooper. I just finished interviewing Dr. David Coughlin for this week's Neurology Podcast. For today's Neurology Minute, I'm hoping you can tell us the main points of your paper. Dr. David Coughlin: The main points of this paper in my mind is that α-Synuclein seed amplification assays from cerebrospinal fluid samples is useful in confirming the presence of synuclein pathology in people with clinically suspected dementia with Lewy bodies. But also that, for people who have synuclein positivity, that the presence of Alzheimer's disease mixed pathology is associated with a worse cognitive progression over time. Dr. Greg Cooper: Thank you Dr. Coughlin, for that summary and for all of your work on this topic. Please check out this week's podcast to hear the full interview and read the full article published in Neurology, CSF α-Synuclein Seed Amplification Assays and Alzheimer's Disease Biomarkers in Dementia with Lewy Bodies. Thank you.

Dr. Greg Cooper talks with Dr. David G. Coughlin about the role of αSyn-SAAs in diagnosing dementia with Lewy bodies and their relationship with Alzheimer disease biomarkers.  Read the related article in Neurology®.  Disclosures can be found at Neurology.org. 

Host: Yuval Zabar, MD Guest: Michelle Mielke, PhD Guest: Henrik Zetterberg, MD, PhD For the latest insights on tau and neurodegeneration biomarkers in Alzheimer's disease (AD), tune in to this recorded presentation featuring Doctor Michelle Mielke and Professor Henrik Zetterberg. Together, they delve into the role of tau in AD, exploring the ‘tau cascade', the current use of tau and neurodegeneration biomarkers in tracking disease progression, and how the AD biomarker landscape may evolve over time. Doctor Mielke is a Professor of Epidemiology and Neurology at the Wake Forest University School of Medicine, and Professor Zetterberg is a Professor of Neurochemistry at the University of Gothenburg. To learn more about tau in Alzheimer's disease, explore the Know Tau medical education platform. Know Tau is created and funded by Biogen and is intended for healthcare professionals only.

Artificial intelligence is rapidly reshaping how we screen, classify, and treat diabetic retinal disease. Professor Aude Couturier, Professor Edoardo Midena, and Professor Reinier Schlingemann discuss real-world AI applications in diabetic retinopathy — from population screening and imaging biomarkers to phenotyping and precision treatment in diabetic macular oedema

In this episode, Dr. Jockers sits down with Dr. Jack Wolfson, board-certified cardiologist and founder of Natural Heart Doctor, to challenge everything you think you know about heart disease. You'll discover why the "100-year heart" isn't a myth but a design principle. They unpack how true health is built through eat well, live well, think well — and why testing, not guessing, changes everything.   You'll learn why lowering cholesterol or blood pressure with medication isn't the same as addressing root causes. Dr. Wolfson explains the real role of inflammation, oxidative stress, metabolic health, and advanced biomarkers in cardiovascular risk. They also discuss fasting, nutrient-dense ancestral nutrition, and why seafood and organ meats play a powerful role in heart longevity.   You'll also explore overlooked drivers of heart disease, including sleep quality, sunlight exposure, mold toxicity, oral health, nervous system alignment, and mental well-being. The conversation reveals how purpose, community, and emotional resilience directly impact cardiovascular outcomes. This episode reframes heart health as a whole-life strategy, not just a lab number.   In This Episode:  00:00 Introduction: The Myth of Sudden Health Decline 00:26 Welcome Back: Introducing Dr. Jack Wolfson 00:57 The 100 Year Heart: A Natural Approach to Cardiovascular Health 04:05 Conventional Medicine vs. Natural Health 07:51 The Importance of Lab Testing and Biomarkers 14:07 Optimal Nutrition for Heart Health 19:11 Lifestyle Strategies for Longevity 25:28 The Power of Positive Thinking and Community 29:12 Conclusion: Resources and Final Thoughts   If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday.   BON CHARGE's Red Light Face Mask helps to restore glow, calm the complexion, and soften the visible signs of aging – all from the comfort of home. Order yours today and start seeing the amazing skincare benefits. Get 15% off now when you go to https://boncharge.com/ and use my exclusive promo code DRJOCKERS.   OneSkin: Get 15% off OneSkin with the code DRJOCKERS at https://www.oneskin.co/DRJOCKERS  #oneskinpod   Superpower:  Head to Superpower.com and use code JOCKERS at checkout for $20 off your membership. Live up to your 100-Year potential. #superpowerpod     "Your heart is designed to live to 100 and beyond. Chronic disease is preventable, not inevitable."      Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio   Resources:   Connect with Dr. Jack Wolfson: Website - https://drjackwolfson.com/   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

Show notes: (0:00) Intro (1:14) What led Dr. Cole to functional medicine and early telehealth (6:13) Why many "healthy" people still feel unwell (11:15) The top 3 blood tests you should ask for (18:58) How inflammation is the real issue (28:21) The "Inflammatory Core 4" foods to cut out (35:26) Carbs, ketosis, and finding what works for your body (40:45) Surprising household toxins that may be harming your health (45:20) Practical steps to reduce exposure and feel better faster (48:48) Where to find Dr. Cole (49:58) Outro Who is Dr. Will Cole?   Dr. Will Cole is a leading functional medicine expert who consults people around the world via webcam, having started the first functional medicine telehealth centers in the world. Named one of the top 50 functional and integrative doctors in the nation, Cole specializes in clinically investigating underlying factors of chronic disease and customizing a functional medicine approach for thyroid issues, autoimmune conditions, hormonal imbalances, digestive disorders, and brain problems.   He is the host of the popular The Art of Being Well podcast and the New York Times bestselling author of Intuitive Fasting, Gut Feelings, Ketotarian, and The Inflammation Spectrum.   Connect with Dr. Cole Website: https://drwillcole.com/ LinkedIn: https://www.linkedin.com/in/drwillcole/ Instagram: https://www.instagram.com/drwillcole   Tune in: https://drwillcole.com/podcast/   Grab a copy: https://drwillcole.com/books-home-page/ Links and Resources: Peak Performance Life - https://buypeakperformance.com/ Peak Performance on Facebook - https://www.facebook.com/livepeakperformance/ Peak Performance on Instagram - https://www.instagram.com/livepeakperformance

Brent Ness, CEO and President of Aclarion,  highlights the challenges of diagnosing and treating chronic lower back pain, a leading driver of healthcare costs and opioid addiction. Traditional MRI and CT imaging do not reveal the biochemical source of pain within spinal discs, leading to misdiagnosis and unsuccessful treatment. The Aclarion technology uses MR spectroscopy to measure pain-causing biomarkers and, through a cloud-based, AI-powered SaaS model, analyzes the raw data and sends the physician a report within minutes. Brent explains, "The diagnosis and accurate treatment planning of back pain are incredibly complex. And when you think about pain management physicians, rehab, all the way up to spine surgery identifying the source of pain accurately leads to better treatment and then obviously better outcomes.There are 266 million people around the world who suffer from chronic low back pain. So I'm not talking about the kind that you had a rough weekend skiing, golfing, or hiking, and you're a little sore. I'm talking about the kind that keeps people from participating in a meaningful life. " "When you think about the joints and the sources of blood flow, the nerves that are all around your spinal cord, the vertebral columns, and there's just a lot of moving parts and a lot of really, let's just call it high-value real estate that can actually be the source of pain. And really, our superpower is to help physicians see the invisible. Meaning that normally when you go to the doctor, and they do a workup on you, they'll use an MRI or a CT scanner. And those modalities are really good at pinpointing anatomical issues that might be causing pain. What we do is we use MR spectroscopy, not to make a picture of your back, but rather to measure the biomarker content inside the discs that are invisible on a normal MRI. And as it turns out, what's inside your disc can actually be the source of pain." #ACON #CLARITYtrial #lowbackpain #spinesurgery #MRSpectroscopy #Biomarkers #AugmentedIntelligence #innovation #ChronicPain #BackPain #MedicalTechnology #AI #HealthcareInnovation #SpineCare #MRI #PainManagement #DigitalHealth #Diagnostics #HealthTech #PatientCare aclarion.com Download the transcript here

Brent Ness, CEO and President of Aclarion,  highlights the challenges of diagnosing and treating chronic lower back pain, a leading driver of healthcare costs and opioid addiction. Traditional MRI and CT imaging do not reveal the biochemical source of pain within spinal discs, leading to misdiagnosis and unsuccessful treatment. The Aclarion technology uses MR spectroscopy to measure pain-causing biomarkers and, through a cloud-based, AI-powered SaaS model, analyzes the raw data and sends the physician a report within minutes. Brent explains, "The diagnosis and accurate treatment planning of back pain are incredibly complex. And when you think about pain management physicians, rehab, all the way up to spine surgery identifying the source of pain accurately leads to better treatment and then obviously better outcomes.There are 266 million people around the world who suffer from chronic low back pain. So I'm not talking about the kind that you had a rough weekend skiing, golfing, or hiking, and you're a little sore. I'm talking about the kind that keeps people from participating in a meaningful life. " "When you think about the joints and the sources of blood flow, the nerves that are all around your spinal cord, the vertebral columns, and there's just a lot of moving parts and a lot of really, let's just call it high-value real estate that can actually be the source of pain. And really, our superpower is to help physicians see the invisible. Meaning that normally when you go to the doctor, and they do a workup on you, they'll use an MRI or a CT scanner. And those modalities are really good at pinpointing anatomical issues that might be causing pain. What we do is we use MR spectroscopy, not to make a picture of your back, but rather to measure the biomarker content inside the discs that are invisible on a normal MRI. And as it turns out, what's inside your disc can actually be the source of pain." #ACON #CLARITYtrial #lowbackpain #spinesurgery #MRSpectroscopy #Biomarkers #AugmentedIntelligence #innovation  #ChronicPain #BackPain #MedicalTechnology #AI #HealthcareInnovation #SpineCare #MRI #PainManagement #DigitalHealth #Diagnostics #HealthTech #PatientCare aclarion.com  Listen to the podcast here

In the first Ask Me Anything episode for this Year of the Fire Horse, host Amelia Phillips answers listener questions on protein milk, the top longevity-focused biomarkers to track, and – one of your favourites – how to lose fat without losing muscle. (PS. Check out Episode 251 for a deep dive into this topic with the amazing Sharelle Grant.) About the host: Amelia Phillips is an exercise scientist, nutritionist, and published researcher (BSc, MNut) with a career spanning 26 years in health. She is the co-founder of Vitality360, a functional health platform that helps people gain deep insights into their health and make targeted changes for lasting vitality.A respected media presenter, Amelia has been featured on Channel 9’s hit show Do You Want to Live Forever? and is dedicated to helping people build a life of energy, connection, and purpose at any age or stage of life.Instagram: @_amelia_phillipsHave a question? Email: ap@ameliaphillips.com.auFind out more at: www.ameliaphillips.com.auDiscover Vitality360: https://v360.health CREDITSHost: Amelia Phillips Audio Producer: Darren RothMusic: Matt Nicholich Production Partner: Nova Entertainment Pty Ltd Healthy Her acknowledges the Traditional Owners of the Land we have recorded this podcast on, the Gadigal people of the Eora Nation. We pay our respects to their Elders past and present and extend that respect to all Aboriginal and Torres Strait Islander cultures. See omnystudio.com/listener for privacy informationSee omnystudio.com/listener for privacy information.

Artificial intelligence is rapidly changing how we understand our health — not just how we feel today, but how fast we're actually aging.On this episode of Live Long, host Peter Bowes continues his personal experiment with Hundred, the AI-powered longevity platform that combines advanced blood testing, wearable data and personalized insights to track biological age and guide smarter health decisions.After introducing the app in an earlier conversation, Peter reconnects with Hundred's founder, Tyler Smith, to go deeper into the idea of a “health operating system” — essentially a personal doctor in your pocket. Together they explore how continuous testing and AI analysis could help prevent disease, spot risks earlier, and motivate lasting behavior change — while also addressing the realities of over-testing, false alarms, privacy concerns and health anxiety.Peter also shares the results of his own first round of testing, what surprised him most, and how he's using the data to shape his approach to longevity and healthy aging.-----JOIN HUNDREDOptimize your healthspan and potentially lower your biological age.  Tyler and the team at HUNDRED are offering $75 in credit for add-on tests and supplements from the HUNDRED marketplace when you sign up at hundred.com/livelongpodcastThis podcast is supported by affiliate arrangements with a select number of companies. We have arranged discounts on certain products and receive a small commission on sales. The income helps to cover production costs and ensures that our interviews remain free for all to listen. Visit our SHOP for more details: https://healthspan-media.com/live-long-podcast/shop/Time-line Mitopure (a highly pure form of Urolithin A) boosts the health of our mitochondria – the battery packs of our cells – and improves muscle strength. Time-line is offering LLAMA listeners a 10% discount on its range of products – Mitopure powders, softgels & skin creams.  Use the code LLAMA at checkout-Fit, Healthy & Happy Podcast Welcome to the Fit, Healthy and Happy Podcast hosted by Josh and Kyle from Colossus...Listen on: Apple Podcasts SpotifyEnergyBits algae snacksA microscopic form of life that could help us age better. Use code LLAMA for a 20 percent discountPartiQlar supplementsEnhance your wellness journey with pure single ingredients. 15% DISCOUNT - use code: MASTERAGING15Disclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showThe Live Long and Master Aging (LLAMA) podcast, a HealthSpan Media LLC production, shares ideas but does not offer medical advice. If you have health concerns of any kind, or you are considering adopting a new diet or exercise regime, you should consult your doctor.

Let's talk about the 4 biomarkers that can be improved quickly with positive lifestyle changes! Schedule a FREE Discovery Call with me here:https://yourlifenutrition.org/nutrition-coaching-application/.Come join our private accountability group, the Goal Getters Group, for all things health, wellness & nutrition! You'll get sample weekly meal plans, recipes, weekly group coaching calls and access to our exclusive Blood Sugar, Wellness, Mindfulness & Movement Challenges to help support you and keep you accountable on your health & nutrition journey AND get access to private messaging with me, your dietitian!Click the link below to join the Goal Getters Group today!https://your-life-nutrition-goal-getters.mn.co/plans/1821314?bundle_token=1724009ab3ed355237fdeeebd2fe1d9f&utm_source=manual.For health & nutrition tips, recipes & more - follow me on:Instagram: https://www.instagram.com/yourlifenutrition/Facebook: https://www.facebook.com/yourlifenutritionrdn/Email: Brittany@yourlifenutrition.orgShop my Favorite Products!Stelo Continuous Glucose Monitor System**I am an Amazon Affiliate and may earn commissions on qualifying purchases.

Your skin is screaming what your blood work is whispering. Dr. Shawana Vali transformed how I understand the visible signs of internal dysfunction, & it's not what the beauty industry wants you to hear. Those wrinkles, breakouts, & pigmentation issues? They're your body's warning system telling you about adrenal fatigue, hormone imbalances, & inflammatory cascades happening deep in your tissues. Ready to look 5 years younger by treating the root cause instead of chasing symptoms? CLICK HERE TO BECOME GARYS VIP!: ⁠⁠https://bit.ly/4ai0Xwg⁠⁠ Connect with Dr. Shawana Vali Website: ⁠⁠https://bit.ly/467cGNl⁠⁠  YT: ⁠⁠https://bit.ly/3NuM9TU⁠⁠  IG: ⁠⁠https://bit.ly/4a6SMV5⁠⁠  TT: ⁠⁠https://bit.ly/4quCzij⁠⁠  FB: ⁠⁠https://bit.ly/4jN5ICM⁠⁠  LI: ⁠⁠https://bit.ly/4pPtqj8⁠⁠  Thank you to our partners H2TABS: “ULTIMATE10” FOR 10% OFF: ⁠⁠https://bit.ly/4hMNdgg⁠⁠ BODYHEALTH: “ULTIMATE20” FOR 20% OFF: ⁠⁠http://bit.ly/4e5IjsV⁠⁠ BAJA GOLD: "ULTIMATE10" FOR 10% OFF: ⁠⁠https://bit.ly/3WSBqUa⁠⁠ SNOOZE: LET'S GET TO SLEEP!: ⁠⁠https://bit.ly/4pt1T6V⁠⁠ COLD LIFE: THE ULTIMATE HUMAN PLUNGE: ⁠⁠https://bit.ly/4eULUKp⁠⁠ WHOOP: JOIN AND GET 1 FREE MONTH!: ⁠⁠https://bit.ly/3VQ0nzW⁠⁠ AION: “ULTIMATE10” FOR 10% OFF: ⁠⁠https://bit.ly/4h6KHAD⁠⁠ A-GAME: “ULTIMATE15” FOR 15% OFF: ⁠⁠http://bit.ly/4kek1ij⁠⁠ PEPTUAL: “TUH10” FOR 10% OFF: ⁠⁠https://bit.ly/4mKxgcn⁠⁠ CARAWAY: “ULTIMATE” FOR 10% OFF: ⁠⁠https://bit.ly/3Q1VmkC⁠⁠ HEALF: 10% OFF YOUR ORDER: ⁠⁠https://bit.ly/41HJg6S⁠⁠ RHO NUTRITION: “ULTIMATE15” FOR 15% OFF: ⁠⁠https://bit.ly/44fFza0⁠⁠ GOPUFF: GET YOUR FAVORITE SNACK!: ⁠⁠https://bit.ly/4obIFDC⁠⁠ GENETIC METHYLATION TEST (UK ONLY): ⁠⁠https://bit.ly/48QJJrk⁠⁠ GENETIC TEST (USA ONLY): ⁠⁠⁠https://bit.ly/3Yg1Uk9⁠⁠ Watch  the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YT: ⁠⁠https://bit.ly/3RPQYX8⁠⁠ Podcasts: ⁠⁠https://bit.ly/3RQftU0⁠⁠ Connect with Gary Brecka IG: ⁠⁠https://bit.ly/3RPpnFs⁠⁠ TT: ⁠⁠https://bit.ly/4coJ8fo⁠⁠X: ⁠⁠https://bit.ly/3Opc8tf⁠⁠ FB: ⁠⁠https://bit.ly/464VA1H⁠⁠ LI: ⁠⁠https://bit.ly/4hH7Ri2⁠⁠ Website: ⁠⁠https://bit.ly/4eLDbdU⁠⁠ Merch: ⁠⁠https://bit.ly/4aBpOM1⁠⁠ Newsletter: ⁠⁠https://bit.ly/47ejrws⁠⁠ Ask Gary: ⁠⁠https://bit.ly/3PEAJuG⁠⁠ Timestamps 00:00 Intro of Show 02:20 Healing the Skin from the Inside Out 06:41 Biomarkers for Accelerated Skin Aging 10:17 Link between Stress and Skin 12:51 Clean Movement in the Beauty Industry 18:04 Inflammatory Skin Conditions 19:13 What's Causing Skin to Age Quickly? 24:55 Exosomes in Skincare Products 32:02 Collagen, Elastin, Fibrin Definitions 36:26 What Happens to Women's Skin during Perimenopause? 43:37 Hormone Replacement Therapy and Peptides on Women 48:03 New Breed Skin Technology 54:05 Less is More for Skincare 1:04:09 What does it mean to you to be an Ultimate Human? The information provided here is for general informational purposes only and should not be considered as medical or clinical advice. It is not intended to diagnose, treat, cure, or prevent any health condition, and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of your physician or other qualified health provider with any questions you may have regarding a medical condition or health objectives. The use of any information provided is solely at your own risk, and the provider of this information is not liable for any consequences arising from its use. Disclosure: Some links to certain products or services are affiliate links, meaning we may earn a commission. Gary Brecka is the owner of Ultimate Human, LLC which operates The Ultimate Human podcast and promotes certain third-party products used by Gary Brecka in his personal health and wellness protocols and daily life and for which Ultimate Human LLC and / or Gary Brecka directly or indirectly holds an economic interest or receives compensation. Accordingly, statements made by Gary Brecka and others (including on The Ultimate Human podcast) may be considered promotional in nature. Learn more about your ad choices. Visit megaphone.fm/adchoices

Show notes: (0:00) Intro (0:49) Dr. Shah's background and personal health crisis (4:55) The most important biomarkers: hs-CRP, A1C, ApoB (7:46) How to track inflammation and metabolic health (13:00) Home tools: bioimpedance scale, grip strength meter (21:09) Nutrition basics: just cut ultra-processed foods (27:09) Hidden toxins in your air, water, and skincare (34:37) Longevity circuit: sauna, cryotherapy, hyperbaric oxygen (38:11) Therapeutic plasma exchange and next-gen biohacking (40:01) Dr. Shah's top 3 health tips anyone can start today (41:18) Where to find Dr. Shah (42:11) Outro Who is Dr. Darshan Shah?   Darshan Shah, MD is a health and wellness specialist, well-known, board-certified surgeon, published author, tech entrepreneur, and founder and CEO of Beautologie and Next Health. As an expert on all body systems, he has performed over 10,000 surgical procedures, including trauma surgery, general surgery and plastic/reconstructive procedures. As a health and wellness specialist, he has advised thousands of patients on how to optimize their well-being and extend their lifespan, culminating in the creation of Next Health, the first health optimization and longevity center to offer life-extending and enhancing technology and treatments in a beautiful, welcoming environment.   Connect with Dr. Shah Website: https://www.drshah.com/ LinkedIn: https://www.linkedin.com/in/darshanshahmd IG: https://www.instagram.com/darshanshahmd/   Grab your free Biomarker guide: https://www.drshah.com/biomarkers   Tune in: https://www.drshah.com/extend Links and Resources: Peak Performance Life Peak Performance on Facebook Peak Performance on Instagram

Linda Brubaker, MD, and Christopher C. Muth, MD, Deputy Editors of JAMA, the Journal of the American Medical Association, discuss articles published from January 17-23, 2026.

Lifestyle changes make a major impact on your health. The cool thing is, you can track these changes with regular blood work and with monitoring at home. In this episode we talk about 4 important biomarkers that can improve with lifestyle changes and what changes to implement to make it happen. If you have questions, or topics that you want to hear about, head over to our Instagrams https://www.instagram.com/bayleethedietitian/ or https://www.instagram.com/brianna.dietitian/ and send us a DM! You can also follow the podcast https://www.instagram.com/mocktailminutes/Featured Mocktails: Liquid IVGorgie  Click play, sip back, and be empowered.

When it comes to longevity, most of the research feels clear around exercise and nutrition. We know how they affect aging and the prevention of the four diseases that kill most people: heart disease, cancer, metabolic disease, and dementia. But where do sleep, stress, and lifestyle actually fit into that picture?  In Part 1 of the 2026 Body Blueprint, Ted explained why most men over 40 age faster than they should.   In Part 2, he broke down why weight loss alone doesn't equal health.   In Part 3, he showed how men should train to preserve muscle and strength with minimal time.   In Part 4, he explained why cardio and cardiovascular fitness are essential for longevity—even if you already lift.   In Part 5, he shared a clear, evidence-based approach to nutrition that supports metabolic health, longevity, and fat loss without quitting your social life or eliminating foods you enjoy.  In Part 6, Ted turns to the most underestimated drivers of how you age: sleep, stress, and lifestyle. He explains why these factors are harder to quantify but just as powerful, how they quietly influence disease risk and recovery, and why ignoring them can undermine even the best training and nutrition plan. This episode puts the final pieces of the longevity puzzle into place.  You'll learn:    How poor sleep drives fat gain, insulin resistance, and hormonal decline  The surprising link between sleep, pain sensitivity, and chronic injuries  How chronic stress accelerates aging even in mentally tough high achievers  Objective ways to measure stress using heart rate, HRV, and blood pressure  The difference between managing stress symptoms vs. fixing root causes    What Ted discusses in this episode:  (00:00) Introduction (04:35) The Importance of Sleep for Longevity (08:42) Hormones and Sleep (16:42) Sleep Hygiene Tips (24:52) The Role of Caffeine and Alcohol in Sleep (29:35) Understanding and Managing Stress (30:08) Understanding Chronic Stress (30:42) The Importance of Recovery (32:07) Defining Stress and Its Effects (35:13) Tracking Stress with Biomarkers (40:08) Strategies for Managing Stress (47:05) The Power of Social Connections (53:12) Conclusion and Final Thoughts

Lenard Adler, MD, explains how clinicians can safely and effectively treat ADHD when bipolar disorder and addiction are also in the picture. He addresses how to distinguish chronic ADHD symptoms from episodic mood disorders, why bipolar disorder is often missed in adults referred for depression or attention problems, and how substance use complicates both diagnosis and medication selection.Dr. Adler also shares guidance on identifying red flags for diversion or misuse, setting appropriate expectations for medication trials, and navigating the limits of current treatment guidelines. The episode closes with a look toward emerging directions in ADHD treatment, including research on emotional dysregulation, executive function deficits, and next-generation neurofeedback approaches.Lenard Adler, MD, is Pottash Professor of Psychiatry and Director of the Adult ADHD Program at NYU Langone Health▶️ Watch Insights on Psychiatry on YouTube00:00 Why ADHD, Bipolar Disorder, and Addiction Must Be Treated Together01:02 What Makes These ADHD Cases So Difficult02:05 ADHD vs. Bipolar Disorder: Key Diagnostic Distinctions04:43 The Link Between ADHD and Addiction05:53 Using Stimulants Safely When Substance Use Is a Concern07:57 Choosing Stimulants vs. Non-Stimulants10:07 How Severity and Comorbidity Shape Treatment Decisions12:06 The Limits of Guidelines and Biomarkers in ADHD Care15:34 Executive Function and Emotional Dysregulation16:13 Where ADHD Treatment Is Headed NextThis episode is intended for psychiatrists, mental health clinicians, and others interested in complex adult ADHD presentations.This discussion is for educational purposes and does not substitute for individual clinical judgment or patient care. Senior Producer: Jon Earle

Video: https://www.youtube.com/watch?v=A6ymQgVLC5cAutism & Parkinson's https://youtu.be/1E53ZYehUCU?si=69pKeFSKi07GGsATHypothyroid Biomarker https://youtu.be/X6CxX9kA6b0?si=Bkr8ZKooNdie-N6IDr. Kristen Lyall, ScD https://youtu.be/cjBR8m82KZQ?si=C-Tclr25oBbid7qGNicole Rincon & links to her other episodes in notes https://youtu.be/jRd7rE38W90?si=i8CvVutA4a1K9NzeDaylight Computer Company, use "autism" for $50 off at https://buy.daylightcomputer.com/autismChroma Light Devices, use "autism" for 10% discount at https://getchroma.co/?ref=autismFig Tree Christian Golf Apparel & Accessories, use "autism" for 10% discount at https://figtreegolf.com/?ref=autismCognity AI for Autistic Social Skills, use "autism" for 10% discount at https://thecognity.com00:00 Serotonin Recap: thalamocortical connections (esp. S1 somatosensory)02:41 Aromatic Amino Acids & UV-sensitive aromatic benzene rings04:56 Personal Sunlight Reversal Host reversed Hashimoto's (2005–2024) via increased sunlight07:58 Cell-Level Roles Serotonin drives neurogenesis, migration, dendrites/spines; T3 matures organelles, myelination & cellular energy11:00 Maternal Thyroid Dependency Fetus relies on maternal T3/T4 until ~weeks 16–20; hypothyroidism as easy, modifiable biomarker for autism/Parkinson's13:07 Substantia Nigra & Basal Ganglia Neuromelanin/dopamine loss in substantia nigra links autism & Parkinson's; disrupts basal ganglia go/no-go orchestration15:44 Mitochondria & Melanin Energy Cytochrome c oxidase produces H2O in ETC; melanin + water coupling provides power 18:00 Hypothyroidism Biomarker Call Undisputed, simple-to-check risk factor; urgent prenatal thyroid screening & sunlight exposure needed20:36 Modern Environment Impact Blue light/low sunlight blocks synthesis; upstream fixes (reflexes, thyroid checks, sunlight) offer prevention/recovery potential22:15 Serotonin & T3 Synergy Serotonin architects connections; T3 engineers cell/organelle maturity & myelination; combined deficits cascade into autism/Parkinson's24:00 Substantia Nigra Detail Loss of neuromelanin/dopamine in substantia nigra (mesencephalon) impairs basal ganglia; ties to movement disorders in both conditions25:44 Mitochondria Water Production Cytochrome c oxidase (complex IV) generates H2O; melanin & water 27:58 Final Synthesis & Implications Serotonin + T3 critical for cell development/myelination; maternal hypothyroidism disrupts both autism/Parkinson's riskX: https://x.com/rps47586YT: https://www.youtube.com/channel/UCGxEzLKXkjppo3nqmpXpzuAemail: info.fromthespectrum@gmail.com

Blood-based Biomarkers, Anti-Amyloid Therapies and BeyondFrom blood-based biomarkers to anti-amyloid treatments, join us as we explore the latest in Alzheimer's disease diagnosis and treatment with Dr. Halima Amjad. This episode will equip you to guide your patients about the latest Alzheimer's diagnostics as well as eligibility, risks and monitoring for anti-amyloid therapies.Claim CME for this episode at curbsiders.vcuhealth.org!Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CMEShow Segments Intro Case Cognitive and functional history reminders Diagnosing Alzheimer's Disease Blood-based biomarkers Anti-amyloid therapy indications, eligibility and contraindications Patient counseling and treatment decisions ARIA Key takeaways Outro Credits Written and Produced by: Natalie Barrett DO, Rachel K Miller MD Show notes, cover art and infographic: Natalie Barrett DO, Rachel K Miller MD, Leah Witt MD Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP    Reviewer: Sai S Achi MD, MBA,FACP Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Guest: Halima Amjad, MD DisclosuresDr. Amjad reports financial relationships with Centene (Advisor) and Craniometrix (Advisor). Relationships have not ended. The Curbsiders report no relevant financial disclosures. The production of this episode was supported by the Penn Geriatrics AGE-SMART Geriatric Workforce Enhancement Grant. This podcast content is solely the responsibility of the authors and does not necessarily represent the official views of the Health Resources and Services Administration or the U.S. Department of Health and Human Services. Sponsor: Babbel Right now get up to 55% off your Babbel subscription at Babbel.com/CURB.Sponsor: QuinceGo to Quince.com/curb for free shipping on your order and 365-day returns. Now available in Canada, too.Sponsor: Sanford GuideSearch for Sanford Guide in the app stores. And, Curbsiders listeners can get 20% off the already very moderately priced yearly subscriptions directly at sanfordguide.com. Go to sanfordguide.com and use the code, CURB at checkout.

On this episode of The Dr. Hyman Show, I'm rejoined by psychiatrist and Harvard professor Dr. Chris Palmer for a conversation that challenges how we've been taught to think about mental illness. For decades, psychiatry has focused on managing symptoms—often without asking what's actually driving them. We discuss a different way of understanding mental health, one that looks beyond diagnostic labels and considers how whole-body biology influences brain function, resilience, and recovery.  Watch the full conversation on YouTube or listen wherever you get your podcasts. In this conversation, we explore: • Why mental illness is rising alongside obesity, diabetes, and other chronic diseases • How whole-body biology influences mood, focus, and emotional resilience • The link between inflammation, metabolic dysfunction, and conditions like depression and bipolar disorder • How nutrition, testing, and lifestyle changes can support real recovery If mental health has ever felt close to home for you or someone you care about, this conversation is meant to offer clarity, compassion, and a place to start. This episode was recorded live at the Eudēmonia Summit, a conference exploring the future of health, longevity, and well-being. Learn more at eudemonia.net. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hymanhttps://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman's Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Timeline, BON CHARGE, Qualia, Paleovalley, Pique and Korrus. Receive 35% off a subscription at timeline.com/drhyman. Upgrade your routine. Head to boncharge.com/hyman and use code DRMARK for 15% off. Go to qualialife.com/hyman and use code HYMAN at checkout for an extra 15% off. Head to paleovalley.com and use code HYMAN20 for 20% off your first order. Secure 20% off your order plus a free starter kit at piquelife.com/hyman.Upgrade your lighting. Enjoy 15% off at korrus.com/drhyman. (0:00) Introduction to mental health crisis and guest Dr. Christopher Palmer (1:31) Eudaimonia Summit and psychiatric revolution (3:06) Traditional and systemic views on psychiatric disorders (7:23) Misconceptions and stigma surrounding mental disorders (10:15) The impact of childhood experiences on mental health (13:28) Root causes of mental illness: Inflammation and brain dysfunction (21:23) Metabolic dysfunction in mental illness (24:15) Significance of metabolism in mental health (27:47) Metabolic nutritional psychiatry and premature mortality (32:34) The mental health revolution and metabolic treatments (34:16) Ketogenic diet as a potential treatment for mental disorders (37:18) Functional and network medicine in mental health (41:13) Biomarkers and potential treatments in metabolic mental health (49:07) Ketogenic therapy and its anti-inflammatory effects (50:12) Historical and emerging paradigms in psychiatry (54:38) Integrating functional medicine into mainstream psychiatry (56:20) Addressing chronic disease in national health discussions (58:22) Closing remarks and further resources (59:02) Podcast outro and call to action

In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Wei-Wu, Executive Chairman at Human Longevity, Inc. Together, they explore how advances in genome sequencing, AI, and multi-layered diagnostics are changing the fight against age-related diseases. Wei-Wu shares why understanding your own genetic risks and combining them with other health data leads to better prevention and a longer healthspan.Wei-Wu explains the value of integrating genome sequencing, advanced imaging, and liquid biopsy to catch diseases like cancer early, before symptoms appear. He draws on real-world examples, including how combining different tests can spot cancers that single methods might miss. The conversation highlights how technology brings down costs, making once-rare insights widely available, and how each person stands to benefit from personalized risk profiles.The episode closes with practical advice: use today's tools to become the CEO of your own health. Wei-Wu urges listeners to embrace data-driven, individualized care and stresses that no single tool or habit holds all the answers. Instead, true longevity comes from a holistic, ongoing approach, one that uses all available knowledge to prevent disease and extend both life and health.Guest-at-a-Glance

Advancing longevity research is about honoring the value of life—and translating that respect into evidence-based prevention. If healthcare is judged by life expectancy + quality of life, longevity medicine may be one of the most meaningful metrics we can pursue: extending health span through early detection, validated biomarkers, and interventions that scale.This unforgettable Expert Panel from the 4th annual Medical Innovation Olympics (#MIO2025) convened all-star global leaders in Longevity and Preventive Medicine who separated hype from reality and outlined what it will take to bring longevity into mainstream care - rigorously, ethically, and accessibly.Topics include: breakthroughs (including epigenetic approaches pointing toward functional restoration of eyesight), biomarkers/endpoints as the “keystone” for faster trials, the TAME (Targeting Aging with Metformin) concept, and the role of standards, education, trust, and shared responsibility—keeping dignity central.Panelists:Dr. David Barzilai (Harvard Medical School; Geneva College of Longevity Science, GCLS) • Dr. Dominik Thor (President, GCLS) • Dr. Mishkat Shehata (Emirates Lifestyle & Longevity Medicine Society) • Keith Comito (Lifespan Research Institute) • Dr. Uma Senthilkumar (Three Five Revive)

Today, I'm excited to bring back the always thought-provoking Joel Greene, author of "The Immunity Code" and "The Way," for a fresh conversation on why true longevity is about so much more than how much muscle you have or the latest diet trend you're following. Joel Greene opens up about the hard lessons he's learned from decades of self-experimentation and reveals why chasing that ideal gym physique might actually backfire as you age.   Episode Timestamps: Welcome & episode introduction ... 00:00:00 The evolving nature of health and homeostasis ... 00:08:29 Beware rigid diet tribes—find nutritional flexibility ... 00:21:41 Biomarkers people miss: fasting insulin and acyl carnitines ... 00:23:11 Chronic ketosis, ATP, and metabolic slowdowns ... 00:25:16 Myth-busting muscle and the limits of bodybuilding for aging ... 00:27:17 Functional movement, flexibility, and big toe strength ... 00:34:29 Simple foundation: daily jumps or hops ... 00:47:41 Sensible protocols for muscle gain after 50 ... 01:00:07 Balance in diet as the true key to insulin sensitivity ... 01:08:06 Rules of thumb: meal timing for insulin ... 01:15:56 Stillness, faith, and feeding your spirit ... 01:21:56 Most abused supplement: Antioxidants ... 01:27:54 Body fat percentage as top longevity marker ... 01:29:12   Our Amazing Sponsors: Quantum Upgrade - Supports nervous system balance without wearables or apps—just effortless, 24/7 quantum energy streaming. With 21+ studies showing measurable improvements in stress and cellular function, it's easy to try for yourself. Visit quantumupgrade.io/NAT and use code NAT10 to start the free trial.   Blue Peptide Spray from Young Goose - Brings the message back loud and clear. With NAD+ APEX™️ to refuel energy, methylene blue to recharge your mitochondria, and GHK-Cu to tell your skin, "Hey, start making that collagen again!" It's longevity science, not cosmetic hype. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.   Mitopure® Longevity Gummies are the only clinically proven Urolithin A gummies supporting mitochondrial health — one of the key hallmarks of aging. Get 35% off a one-month subscription at Timeline.com/Nat2026 *Special deal through January 2026.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Let us know what you think! Text us!SPONSORED BY: PURE LIBERTY LABS, PRECISION WELLNESS GROUP, and THE SPECIAL FORCES FOUNDATION In this episode of Security Halt!, Deny Caballero is joined by Corey Russell and Peyton Smith, co-founders of ROE Labs, to discuss the realities of military transition, mental health, and brain health after service. The conversation explores how cumulative exposure, overpressure, and TBI affect veterans—and why research-backed supplements, education, and community support are critical during transition. Corey and Peyton share how their shared experiences led them to build a purpose-driven company focused on protecting the brain and empowering veterans to pursue new opportunities after the uniform comes off. 

In this episode, Dr. Will Cole sits down with Geviti founder Nate Graville for an eye-opening look at how artificial intelligence, advanced diagnostics, and personalized data are reshaping the future of health. Nate shares how losing his father to cancer led him to build a platform that combines comprehensive bloodwork, wearables, and AI to help people become “default healthy.” They explore AI bias, the future of lab-on-chip technology, peptides, and the ethics of merging technology with medicine. For all links mentioned in this episode, visit www.drwillcole.com/podcast.Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Sponsors:Go to tonum.com/WILLCOLE or use code WILLCOLE for 10% off your first order.Go to Quince.com/willcole for free shipping on your order and three hundred and sixty-five-day returns. Now available in Canada! If you're ready to finally understand what your gut has been trying to tell you, ask your provider for the Gut Zoomer by Vibrant Wellness — or find a Vibrant-certified provider today at vibrant-wellness.com/willcole.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What happens when life takes everything from you—and you're forced to decide who you become next?In this deeply moving conversation, Mark Divine sits down with Cody Lakefield, co-founder of Long Ship Men and Look Health, to explore the intersection of trauma, healing, proactive health, brotherhood, and purpose.Cody shares his journey through profound personal loss, responsibility, and suffering—and how those experiences led him to build systems that help men reclaim ownership of their health, their inner lives, and their relationships with other men.From personalized biomarker testing and preventative health… to grief, PTSD, faith, and the power of men rowing together… this episode is about moving from survival to meaning.If you're a leader, father, entrepreneur, or man navigating pressure in silence, this conversation offers a different path forward—one rooted in awareness, courage, and community.In this episode, you'll discover:Why proactive health matters more than “sick care”How understanding biomarkers gives you agency over your bodyWhy trauma doesn't resolve itself through willpower aloneThe danger of carrying everything in isolationHow brotherhood accelerates healing and resilienceWhy purpose is often forged through suffering, not comfortHow to move from surviving life to living it intentionallyJoin The Unbeatable Leader Challenge - January 13thThe Unbeatable Leader Challenge is back starting January 13th, this time we're making it FREE to join on this training. Kick off 2026 with a growth mindset to win the winner war, achieve front-sight focus, and build an unbeatable team in 2026. → https://www.unbeatableleader.comUnlock your full potential and lead with courage, clarity, and purpose—join The Unbeatable Tribe and become truly unbeatable in life and leadership.Join for free for 7 days: The Unbeatable Tribe → https://www.skool.com/unbeatable-mastery-tribe/aboutBUBS NATURALS - Use Code Unbeatable for 20% OFFI use BUBS Naturals daily for focus, recovery, and hydration—all built on a mission to honor a fallen Navy SEAL. Use code UNBEATABLE for 20% off any one time purchase or subscription at bubsnaturals.comCody Links:Website: https://www.lookhealth.com/, https://www.longshipmen.com/Book: https://a.co/d/2iDuYdy Instagram: https://www.instagram.com/raven_cody7/LinkedIn: https://www.linkedin.com/in/cody-lakevold-458b311b/?originalSubdomain=caX: https://x.com/CodyLakevoldMark Links: Website: https://markdivine.comThe Unbeatable Tribe: https://www.skool.com/unbeatable-mastery-tribe/aboutDivine Inspiration Newsletter: https://markdivine.com/newsletterYouTube: https://www.youtube.com/@markdivineofficial/Instagram: https://www.instagram.com/markdivineofficialLinkedIn: https://www.linkedin.com/in/markdivine/Facebook: https://www.facebook.com/markdivineofficial/Subscribe to https://www.youtube.com/@markdivineofficial for more inspiring conversations on leadership, growth, and impact.Rate and review the show to help us reach more listeners.Share your thoughts and takeaways in the comments!#MarkDivine #CodyLakefield #MensWork #MentalHealth #TraumaHealing #PreventativeHealth #Biomarkers #Brotherhood #PurposeDrivenLife #LeadershipDevelopment #Resilience #UnbeatableMind #LongShipTimestamps:00:00 Introduction to the Biomarkers, LookHealth, Longship Men00:38 Mark Divine's Leadership Challenge01:28 Welcome to the Mark Divine Show01:54 Introducing Cody Lakevold02:52 Cody's Health Ventures04:30 Challenges in Healthcare Access06:39 Cody's Personal Journey Begins12:38 Family Struggles and Personal Loss20:32 Coping with Family Tragedies40:31 Struggling with Nightmares and Suicidal Thoughts42:16 Turning to Alcohol for Relief43:41 Seeking Therapy and Finding Hope45:35 Discovering MDMA Therapy46:16 A Life-Changing MDMA Session53:04 Rebuilding Life and Relationships54:12 Creating Raven Lake Investments01:00:05 The Birth of Long Ship01:11:24 The Vision for Long Ship01:21:03 Conclusion and Future PlansSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In an era where health insights are becoming increasingly personalized, it is always inspiring to meet innovators like Jason Moore who are pushing the boundaries and expanding resources. Jason is the CEO and founder of Spren, a cutting-edge platform that uses smartphone-based tech to measure body composition, HRV, and metabolic signals – all while providing personalized nutrition and 24/7 AI coaching. For the past eleven years, Jason has immersed himself in the world of biomarkers, dedicating his career to making advanced physiological insights accessible to everyday users. As a self-described "aggressive learner", Jason is passionate about solving complex health problems through science, innovation, and a team of world-class researchers… This discussion outlines: What digital biomarkers actually are and why they're transforming modern health and performance tracking. Why HRV is considered the most comprehensive biomarker for overall well-being, resilience, and stress response. How advanced body composition analysis works using only a smartphone. Whether you're a fitness coach, daily gym-goer, or someone curious about optimizing your health, this conversation offers a deep dive into the tech reshaping how we measure human performance. You can connect with Jason by following him on Instagram and LinkedIn!