Podcast appearances and mentions of Donald C Goff

Dr. Donald C. Goff, Marvin Stern professor of psychiatry at NYU Grossman School of Medicine, gives an overview of a new combination drug recently approved by the U.S. Food and Drug Administration for the treatment of schizophrenia. It will be marketed as Cobenfy, and its component active ingredients are xanomeline and trospium chloride, representing the first non-dopaminergic antipsychotic approved by the FDA. Dr. Goff briefly explores the decades of pharmaceutical treatment of schizophrenia and lays out the steps toward developing the new combination drug. He offers details on next steps, treatment, more extensive trials of the new drug, related approaches, and refers listeners to his editorial for prescribing information. His guest editorial, “At Last, a Nondopaminergic Agent for the Treatment of Schizophrenia: The Combination of Xanomeline and Trospium (Cobenfy),” is published in the March-April 2025 issue of The Journal of Clinical Psychopharmacology.

In a study published on August 31, 2023, in the Journal of the American Medical Association, psilocybin showed promise as a treatment for major depressive disorder (MDD). JAMA Associate Editor Dr. Donald C. Goff, speaks with publication author Dr. Charles L. Raison, from the Usona Institute, about the study, as well as Dr. Rachel Yehuda from Mount Sinai School of Medicine, who wrote an accompanying editorial about the potential benefits of psychedelic therapies. Pacific Neuroscience Institute's director of Treatment & Research In Psychedelics Center, Dr. Keith Heinzerling and PNI director Dr. Daniel Kelly were a co-investigators in this study.

Interview with Donald C. Goff, MD, author of Association of Psychiatric Disorders With Mortality Among Patients With COVID-19

Interview with Donald C. Goff, MD, author of Association of Psychiatric Disorders With Mortality Among Patients With COVID-19

Interview with Donald C. Goff, MD, author of Association of Psychiatric Disorders With Mortality Among Patients With COVID-19

Voltamos com mais um caso clínico. Dessa vez, trouxemos um assunto que é desconfortável ao clínico, mas muito presente em nossos plantões. Conhece algum caso de psicose secundária? Compartilha com a gente no Instagram @tadeclinicagem ou no e-mail tadeclinicagem@gmail.com! Aviso do final: não teremos episódios novos no Natal e no Ano Novo! Boas festas! REFERÊNCIAS: Jingle Bells 7 de Kevin MacLeod está licenciada sob uma licença Creative Commons Attribution (https://creativecommons.org/licenses/by/4.0/) Artista: http://incompetech.com/ #### Freudenreich, Oliver, S. Charles Schulz, and Donald C. Goff. "Initial medical work‐up of first‐episode psychosis: a conceptual review." Early Intervention in Psychiatry 3.1 (2009): 10-18. #### Dalgalarrondo, Paulo. Psicopatologia e semiologia dos transtornos mentais. Artmed Editora, 2018. ####

Interview with Donald C. Goff, MD, author of Randomized Multicenter Investigation of Folate Plus Vitamin B12 Supplementation in Schizophrenia