Podcasts about Combination

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Best podcasts about Combination

Show all podcasts related to combination

Latest podcast episodes about Combination

The Sports Bar
The combination of coaches that make most sense for the Bills

The Sports Bar

Play Episode Listen Later Jan 23, 2026 28:53


Several head coaching interviews have already been conducted by the Bills, with more on the way in the coming days. Lance Lysowski of The Buffalo News joins Danger and Battaglia in The Sports Bar to pick apart the list of candidates and what combination of names and abilities could lead to success for the Bills next season. Love the show? Share it! Listen, subscribe, and tell a friend!

One Minute Scripture Study
Revealing a Secret Combination

One Minute Scripture Study

Play Episode Listen Later Jan 22, 2026 2:44


I've always (out of pure curiosity, of course) wondered what these secret combinations are. Let's reveal the most powerful one here in Moses 5:31. And grab study guides for the whole family here: - To get Cali's scripture study guide for adults click here: https://comefollowmestudy.com/shop/ Discount code: OMSSOr purchase on Amazon: https://a.co/d/4qocgeU-Grab Kristen's copies of helpful PDFs and study guides here: https://shop.kristenwalkersmith.com/products/ Check out her monthly Come Follow Me YouTube videos here: https://kristenwalkersmith.com/youtube/Get our NEW 365-day Old Testament daily devotional book in Costco stores in Utah, Idaho, ArizonaOr purchase on Amazon: https://a.co/d/0p3Ds0t Hosted on Acast. See acast.com/privacy for more information.

On Iowa Podcast
Pinning Combination Podcast: K.J. Pilcher and Dick Briggs (1/21/26)

On Iowa Podcast

Play Episode Listen Later Jan 21, 2026 40:57


The Gazette sports writer K.J. Pilcher and Iowa wrestling legend Dick Briggs discuss the past week of wrestling with Iowa colleges and universities including the matchup between Iowa and Penn State January 16.

Docking Bay 77
1977 Limited Series, Capricorn 1

Docking Bay 77

Play Episode Listen Later Jan 21, 2026 77:39


This week's episode is a two-fer of sorts. It continues our sci-fi movie month series and kicks off our 1977 limited series. Our limited 1977 series will cover multiple films and albums from that year. Combination sci-fi flick and political thriller, Capricorn 1 gave Dayton plenty to say. ;-)Send us a textTwitter @dockingbay77podFacebook @dockingbay77podcastdockingbay77podcast@gmail.compatreon.com/dockingbay77podcast https://www.youtube.com/@DockingBay77podcast https://dockingbay77pod.buzzsprout.com

Shared Accounts with CU Times
The Importance of the CDFI and Credit Union Combination

Shared Accounts with CU Times

Play Episode Listen Later Jan 16, 2026 45:39


From a Savannah, Ga. church basement to CDFI certification, a tiny credit union's journey offers big lessons. Also, Michael finds out what skills Natasha and Producer Zach would add with unlimited time. Do they use the question as an excuse to discuss eagles and make a dirty joke, respectively? Listen to find out.

On Iowa Podcast
Pinning Combination Podcast: K.J. Pilcher and Dick Briggs (1/14/26)

On Iowa Podcast

Play Episode Listen Later Jan 15, 2026 63:14


The Gazette sports writer K.J. Pilcher and Iowa wrestling legend Dick Briggs discuss Iowa NCAA wrestling.

TrueLife
A Conversation W/François Vix: Beauty, Health, & the Immune System

TrueLife

Play Episode Listen Later Jan 14, 2026 90:38


One on One Video Call W/George https://tidycal.com/georgepmonty/60-minute-meetingSupport the show:https://www.paypal.me/Truelifepodcast?locale.x=en_USKeywordsbeauty, health, SOD, immune system, dermatology, Francois Vix, beauty industry, skincare, natural products, holistic healthSummaryIn this enlightening conversation, George and Francois Vix delve into the intricate relationship between beauty, health, and the immune system. Francois shares his extensive experience in the beauty industry, emphasizing that true beauty transcends mere decoration and is deeply rooted in health and well-being. The discussion highlights the significance of superoxide dismutase (SOD) as a critical enzyme that plays a vital role in maintaining cellular health and beauty. They explore various applications of SOD, from dermatology to athletic performance, and address the importance of a holistic approach to beauty that combines science with human experience.TakeawaysBeauty is not just decoration; it's a negotiation with time.Health is more important than beauty, as true beauty stems from health.SOD (superoxide dismutase) is a critical enzyme for cellular health.The immune system plays a foundational role in achieving beauty.Beauty is a reflection of a life well lived, not just physical appearance.SOD can help with various health issues, including skin conditions and athletic recovery.Combination therapy, including nutraceuticals and topical treatments, is essential for optimal results.Generosity and love are among the most beautiful aspects of life.The mirror reflects honesty, prompting self-reflection and growth.Clinical trials and scientific research are crucial for validating health products. TitlesThe Essence of Beauty: A Deeper ConversationFrancois Vix: A Journey Through the Beauty IndustrySound bites"Beauty is biology in motion.""SOD is the enzyme of life.""We can help with recovery."Chapters00:00 The Essence of Beauty: A Negotiation with Time02:28 Francois Vix: A Journey Through the Beauty Industry10:22 Beauty Beyond Decoration: Health and Radiance14:31 The Science of SOD: A Breakthrough in Beauty and Health38:17 The Immune System: The Foundation of True Beauty45:31 Vitiligo and Melasma: The Duality of Skin Conditions52:24 The Impact of Vitiligo on Life and Identity53:42 Combining Ingredients for Optimal Skin Health55:35 The Role of SOD in Dermatology and Aesthetic Treatments57:12 SOD and Its Potential in Cancer Treatment01:01:17 Reconstructive Surgery and Recovery Enhancements01:06:30 SOD in Sports Medicine and Athletic Recovery01:09:42 The Focus on Dermatology and Aesthetic Medicine01:11:00 Philosophical Perspectives on Aging and Beauty01:17:40 The Changing Landscape of Beauty in the Digital Age01:19:35 The Importance of Patience in Nutraceuticals01:20:19 Oral vs. Topical Products in Beauty01:21:18 Ethics in the Beauty Industry01:24:29 The Intersection of Science and Human Experience01:27:45 Finding Beauty Beyond Appearancehttps://www.glisodin.com/ One on One Video call W/George https://tidycal.com/georgepmonty/60-minute-meetingSupport the show:https://www.paypal.me/Truelifepodcast?locale.x=en_US

The Morning Show w/ John and Hugh
HR3 - New era of Falcons football beginning after combination of on & off field changes

The Morning Show w/ John and Hugh

Play Episode Listen Later Jan 13, 2026 37:51


HR3 - New era of Falcons football beginning after combination of on & off field changes In hour three Mike Johnson, Beau Morgan, and Ali Mac let listeners call in and give their take on who they want to see be the next Head Coach of the Atlanta Falcons, and what they want the next Falcons uniforms to look like in the Wake Up Call! Then, Mike, Ali, and Beau continue to talk about the Atlanta Falcons teasing on social media yesterday that new uniforms are coming in April, speculate on what the new uniforms could look like, talk about what they want they new uniforms to look like, talk about how Matt Ryan is going to speak to the media today for the first time since being named the Falcons President of Football, let you hear what Matt had to say on CBS about what to expect from the Falcons with him as the President of Football, react to what Matt had to say, continue to react to the Falcons announcing yesterday that they have completed an interview with former Baltimore Ravens Head Coach John Harbaugh and former Miami Dolphins Head Coach Mike McDaniel, and explain why they think Mike McDaniel isn't the best head coaching candidate for the Falcons, but would be a good fit as the Falcons next offensive coordinator. The Morning Shift crew also reacts to a tweet that basically said the Atlanta Falcons, knowing they can't meet the demands of former Baltimore Ravens Head Coach John Harbaugh, only interviewed Harbaugh to make the fans happy, explain why they think the Falcons next Head Coach needs to be hungry and not already having passed the peak of their success, and then close out hour three by diving into the life of Beau “Squidbilly” Morgan in The Life of Squid!

On Iowa Podcast
Pinning Combination Podcast: K.J. Pilcher and Dick Briggs - College Edition (1/8/26)

On Iowa Podcast

Play Episode Listen Later Jan 8, 2026 55:40


The Gazette sports writer K.J. Pilcher and Iowa wrestling legend Dick Briggs talk about all things Iowa high school and Iowa universities/colleges wrestling.

The City That Breeds
CTB Show 558: Combination THC Mounjaro Blue Chew

The City That Breeds

Play Episode Listen Later Jan 6, 2026


New Year not so new podcast! The Podgang kicks it off by laugh crying at the Venezuela situation, catch up on all things holiday and new year, mourn the loss of the 8×10 and more on the front half. Then, of course, the Stranger Things finale and Heated Rivalry is discussed! 2026! Discord: https://discord.gg/ntcQjmWJZW

The Rise Guys
EASTER AND WEED, PROBABLY NOT A GOOD COMBINATION: HOUR TWO

The Rise Guys

Play Episode Listen Later Jan 2, 2026 31:39


OPEN PHONES: I SMOKED WEED ON EASTER AND IT CHANGED MY LIFE THE FIRST EVER SPERM RACE IS TODAY, REALLY.. DID ANYBODY WATCH THE SPERM RACE?

Optometric Insights Media
#73 The Myopia Podcast: Combination Treatment is it for Everybody? With Anita Gulmiri

Optometric Insights Media

Play Episode Listen Later Jan 1, 2026 29:49


More Than a Pretty Face
The Rise of Male Aesthetics: Botox, Hair Restoration & More

More Than a Pretty Face

Play Episode Listen Later Dec 31, 2025 24:38


In this episode of More Than A Pretty Face, Dr. Azi speaks with two leading dermatology experts about modern aesthetic and hair restoration treatments. First, Beverly Hills cosmetic dermatologist Dr. Ardalan Minokadeh shares how neuromodulators, fillers, and facial contouring should be approached differently in men. Then, New York–based dermatologist Dr. Marc Avram breaks down evidence-based hair loss treatments, from medications and PRP to at-home and in-office laser therapies. The episode wraps with practical insights on confidence, aging, and personalized care. Timeline of what was discussed: 00:00 – Intro 00:18 – Submit questions 00:34 – Meet Dr. Ardalan 01:05 – Conference context 01:40 – Men & aesthetics 02:25 – Botox dosing in men 03:10 – Brow positioning 03:45 – Crow's feet focus 04:20 – Dosing approach 05:05 – Icing & comfort 06:05 – Lip filler in men 07:15 – Neck & lower face 08:10 – Trap tox 08:55 – Jawline trends 09:35 – Chin projection 10:25 – Rapid-fire Q&A 11:55 – Where to find Dr. Ardalan 12:30 – Transition 12:51 – Meet Dr. Avram 13:05 – Hair restoration overview 13:35 – PP405 discussion 14:25 – Diagnosing hair loss 15:05 – Medical therapy 15:50 – PRP & regeneration 16:35 – Treatment timelines 17:20 – Combination therapy 18:00 – At-home laser caps 18:45 – In-office lasers 19:35 – Laser mechanism 20:20 – Emerging treatments 21:05 – Choosing a laser cap 21:45 – Supplements 22:50 – Where to find Dr. Avram 23:14 – End   ______________________________________________________________ Follow Ardalan Minokadeh on Instagram: @doctor.ardalan Dr. Ardalan Minokadeh is a board-certified, cosmetic fellowship–trained dermatologist based in Beverly Hills. He specializes in advanced injectable treatments, aesthetic dermatology, and facial balancing for both men and women. Known for his precise, anatomy-driven approach, Dr. Minokadeh is an expert in neuromodulators and dermal fillers, with a strong focus on natural, tailored results and patient-centered care.   Follow Marc Avram on Instagram: @drmarcavram Dr. Marc Avram is a board-certified dermatologist and internationally recognized leader in hair restoration and cosmetic dermatology, based on New York City's Upper East Side. He is the author of multiple textbooks and peer-reviewed publications and is widely regarded for his expertise in medical, regenerative, and laser-based hair loss treatments. Dr. Avram is known for his evidence-based approach, clinical innovation, and dedication to personalized patient care. ______________________________________________________________ Submit your questions for the podcast to Dr. Azi on Instagram @morethanaprettyfacepodcast, @skinbydrazi, on YouTube, and TikTok @skinbydrazi. Email morethanaprettyfacepodcast@gmail.com. Shop skincare at https://azimdskincare.com and learn more about the practice at https://www.lajollalaserderm.com/ The content of this podcast is for entertainment, educational, and informational purposes and does not constitute formal medical advice. © Azadeh Shirazi, MD FAAD.

On Iowa Podcast
Pinning Combination: College edition, K.J. Pilcher and Dick Briggs, 12/23/2025

On Iowa Podcast

Play Episode Listen Later Dec 23, 2025 41:54


The Gazette sports writer K.J. Pilcher and Iowa wrestling legend Dick Briggs go over last week's results in Iowa college wrestling.

Christmas Podding
Christmas Podding - What is the best Christmas Sandwich Combination of all time?

Christmas Podding

Play Episode Listen Later Dec 19, 2025 39:19


Today on Australia's ONLY Christmas Podcast we have a Podcast a  day, every day from now till Christmas. We uncover the best Christmas Sandwich Combination of all time. We look at all the best flavors and fillings that come out at this time of year and see what matches best for the ultimate Sarni. Our Tinsel is in a Tangle with a new Holiday Travel Trend that can make your next trip super uncomfortable and may even get you a little hot under the festive colour Plus Are you an annual Ornament Collector. The cute tradition of collecting the same type of decoration year upon year and why it ads to the joy of the season With your Aussie Hosts Liam and Ness talking all things Christmas every day with a daily podcast from now till Christmas Day Tune In to Christmas Talk Radio. Our 24/7 Christmas Radio Station talking All Things Christmas, Non-Stop every day of the week. Find us on the I Heart Radio Ap or Click on the link to listen below https://tunein.com/radio/Christmas-Talk-Radio-s345979/

On Iowa Podcast
Pinning Combination: K.J. Pilcher and Dick Brigs (12/17/25)

On Iowa Podcast

Play Episode Listen Later Dec 17, 2025 45:15


The Gazette sports writer K.J. Pilcher and Iowa wrestling legend Dick Briggs how the Iowa Hawkeyes, Iowa State Cyclones, UNI Panthers and the small college wrestling teams fared and their upcoming meets/duals.

PeerVoice Clinical Pharmacology Audio
Colin Russell, PhD / John Watkins, MBBCh, BSc - A Shot in the Arm: Leveraging Combination Vaccines for Global Health Impact

PeerVoice Clinical Pharmacology Audio

Play Episode Listen Later Dec 17, 2025 17:26


Colin Russell, PhD / John Watkins, MBBCh, BSc - A Shot in the Arm: Leveraging Combination Vaccines for Global Health Impact

Redefining Disability
It's a Combination of Hockey, Nordic Skiing and Bumper Cars

Redefining Disability

Play Episode Listen Later Dec 15, 2025 36:16


Josh Pauls was born without a tibia in both legs and had them both amputated at 10 months old. At age eight, he would be introduced to the game of sled hockey. Within eight years of first trying out the sport, he was called up to his first world championship team. Pauls made his Paralympic debut at the Paralympic Winter Games Vancouver 2010, where he was the youngest player on the team at 17. He would later serve as captain for the U.S. sled hockey team at the 2018 and 2022 Paralympic Games. Pauls is the only sled hockey player to win four Paralympic gold medals. He is the author of “Lessons Learned: My Journey to the Podium” and hopes to be a professional hockey coach when his sled hockey career is finished.

Leadership BITES
The Dark Pattern: The Hidden Dynamics of Corporate Scandals with Guido Palazzo

Leadership BITES

Play Episode Listen Later Dec 13, 2025 50:30 Transcription Available


In this episode of Leadership Bites, I interview Guido Palazzo, Professor of Business Ethics,  University of Lausanne, who explores the dark side of corporate behaviour and the systemic issues that lead to ethical failures. We discuss Guido's background, the concept of his brilliant book 'The Dark Pattern: The Hidden Dynamics of Corporate Scandals' in corporate scandals, and the importance of understanding the systems and cultures that allow unethical behaviour to thrive. The conversation delves into the psychological aspects of corporate culture, the slippery slope of ethical compromise, and the need for organisations to create environments that promote ethical decision-making. Ultimately, we highlight the importance of awareness and proactive measures to prevent ethical failures in business.TakeawaysGuido focuses on the absence of ethics in business.Corporate scandals often involve good people making bad decisions.Systems, not just individuals, drive unethical behaviour.Leadership plays a crucial role in shaping organisational culture.Group dynamics can lead to conformity and ethical blindness.The slippery slope of compromise can lead to significant ethical failures.Survival instincts can overshadow ethical considerations in the workplace.Creating a 'bright pattern' can help organisations avoid ethical pitfalls.Awareness and proactive measures are essential for ethical business practices.The importance of having a court jester to provide honest feedback in organisations.Key Moments & Chapters00:00 Introduction to Ethics and Corporate Responsibility03:03 Guido's Background and Academic Journey05:37 Understanding Ethics in Business08:49 The Role of Systems in Ethical Failures11:45 Exploring Corporate Scandals and Dark Patterns14:35 The Impact of Leadership on Organizational Culture17:41 Group Dynamics and Ethical Decision Making20:30 The Combination of Dark Patterns in Corporations23:28 Survival and Ethical Compromise in Business26:12 Conclusion: The Human Element in Corporate Ethics26:42 The Dark Patterns of Corporate Culture29:39 The Slippery Slope of Compromise33:16 The Illusion of the Messiah in Leadership40:13 The Disconnect Between Leadership and Reality44:11 Finding the Bright Pattern in Dark TimesTo find out more about Guy Bloom and his award winning work in Team Coaching, Leadership Development and Executive Coaching click below.The link to everything CLICK HEREUK: 07827 953814Email: guybloom@livingbrave.com Web: www.livingbrave.com

MIB Agents OsteoBites
Results of a phase II trial of olaparib in combination with ceralasertib in patients with recurrent and unresectable osteosarcoma

MIB Agents OsteoBites

Play Episode Listen Later Dec 12, 2025 55:35


Results of a phase II trial of olaparib in combination with ceralasertib in patients with recurrent and unresectable osteosarcomaOsteosarcoma Webinar Series: Katie Janeway, MD and Suzanne Forrest, MD join us on OsteoBites to discuss results of a phase II trial of olaparib in combination with ceralasertib in patients with recurrent and unresectable osteosarcoma.Dr. Janeway received her MD and MMSc from Harvard Medical School. She completed her pediatrics residency and her Pediatric Hematology-Oncology fellowship at Boston Children's Hospital and Dana-Farber Cancer Institute. She is an Associate Professor of Pediatrics, a Senior Physician who cares for young people with sarcoma, and Director of Clinical Genomics. Dr. Janeway's research is focused on precision oncology and bone sarcomas. She leads clinical trials both as an independent investigator and as the Chair of the Children's Oncology Group (COG) Bone Tumor Committee. The Janeway Laboratory leads several studies, which have enrolled and sequenced more than 2,500 patients with childhood cancers. They are using this data to deepen the understanding of clinical and genomic factors explaining prognosis and treatment response, and resistance, with a focus on sarcomas. In collaboration with Count Me In, the group is innovating patient partnerships in sarcoma research.Dr. Forrest completed her medical school training at Yale University, followed by pediatrics training in the Boston Combined Residency Program. She then pursued a pediatric oncology fellowship at Dana-Farber Cancer Institute / Boston Children's Hospital. Currently, she serves as an Assistant Professor of Pediatrics at Harvard Medical School and an Attending Physician in the Department of Hematology/Oncology at Dana-Farber / Boston Children's Cancer and Blood Disorders Center. Her research focuses on developing novel clinical trials that utilize cancer genomics to guide treatment strategies for pediatric solid tumors.After a short presentation on this research, they will take questions from attendees. Share your questions in advance with us at Christina@MIBAgents.org.

On The Pen: The Weekly Dose
Mounjaro vs. New Obesity Drugs: Why Wave-007 Is Stealing the Spotlight

On The Pen: The Weekly Dose

Play Episode Listen Later Dec 9, 2025 34:00


Episode Timeline & Main Topics 00:00 — Opening & Community Update • First week doing the podcast fully live thanks to the On The Pen community • Overview of why this week's news is a major turning point in obesity medicine 02:30 — Introducing the “One-and-Done” Obesity Drug (Wave Life Sciences) • WVE-007 early data drops • Why this therapy is unlike GLP-1s or any nutrient-stimulated hormone • Fat loss results and lean-mass increase 06:30 — How Wave-007 Works: INHBE Gene Silencing • Mechanism behind visceral fat reduction • Why this shifts the field toward “quality of weight loss” 09:15 — Why Lean-Mass Preservation Matters • Current GLP-1 medications and muscle loss • Why women dominate trial enrollment and the larger implications • Medicare patients and the coming wave of GLP-1 coverage 13:45 — The Future of Maintenance Therapies • Fractyl Health Revita results • Lilly's orforglipron maintenance design • Why “holding the line” after GLP-1 therapy is the next major category 17:30 — Amylin Agonists: Cagrelintide vs. Eloralintide • Novo's delays and the strategy behind them • Lilly's surprising phase 2 results (up to 20% weight loss) • Combination therapies with tirzepatide or retatrutide 22:30 — FDA Pipeline Acceleration • Potential removal of traditional phase 3 trials • How this speeds up the arrival of next-generation therapies 24:15 — Oral GLP-1 Small Molecules (Structure Therapeutics) • Alaniglipron data and the stock surge • Comparisons to orforglipron and past failures like denuglipron • Why Dave remains skeptical 28:40 — Sponsor Break: Shed & Shapa • Access, coaching, and patient support • Using a numberless scale to build a healthier relationship with weight tracking 31:10 — Counterfeit Ozempic Warning • New fake lot discovered in U.S. pharmacies • How to identify counterfeit pens • Why this should be a national headline • The broader question of drug supply-chain vulnerability 36:00 — Closing Thoughts on the Future of Obesity Medicine • Moving from “more weight loss” to “better weight loss” • Why the field is closer than ever to reshaping obesity as a disease • Gratitude for the community making full-time coverage possible Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Joe DeCamara & Jon Ritchie
Dick Vermeil: Eagles Issues Are A Combination Of Things

Joe DeCamara & Jon Ritchie

Play Episode Listen Later Dec 5, 2025 11:26


Dick Vermeil joins the 94 WIP Morning Show sharing that he believes that there is a combination of things that are the issue. However, he believes the Eagles will beat the Chargers.

The Remedy Revolution Podcast
BOMBSHELL Vaccine Study with Nicolas Hulscher of the McCullough Foundation

The Remedy Revolution Podcast

Play Episode Listen Later Dec 3, 2025 55:37


Got a show or guest idea? Send us a text!For the full report, visit: https://mcculloughfnd.org/pages/autism-research-reportFor updated research, follow @nichulscher on XFor decades, the causes behind the relentless rise in autism have been hotly debated. Some claim it's due to better diagnosis or changing definitions; others point to environmental stressors and genetics. Yet until now, no comprehensive analysis has ever examined all potential factors—genetic, environmental, immunologic, and iatrogenic—together within a single scientific framework.The McCullough Foundation's landmark report, Determinants of Autism Spectrum Disorder, represents the most exhaustive synthesis ever conducted on the causes of autism. Drawing from over 300 peer-reviewed studies across epidemiology, clinical medicine, toxicology, immunology, and molecular biology, this analysis provides an authoritative, data-driven evaluation of how vaccination and other determinants contribute to autism risk.By comparing the strength, direction, and biological plausibility of every major proposed risk factor, this landmark report delivers unprecedented clarity: autism is a multifactorial neurodevelopmental disorder—but one major, modifiable factor stands out above all others.Combination and early-timed routine childhood vaccination emerges as the single most significant driver of autism risk, supported by convergent mechanistic, clinical, and epidemiologic evidence.Support the show

Front and Center
The Combo Combination: with Brennan McGrath and Kapono Chung

Front and Center

Play Episode Listen Later Dec 3, 2025 72:15


This week, we are thrilled to welcome Brennan McGrath and Kapono Chung to the show! They are Partners at Combo, a strategic creative agency that uses strategy and design to unlock what's next. Their work spans from deep research and thorough strategy to design and beyond. They've worked with brands like Away, Target, Nike, Aldo, GAP, Instagram, Bed Bath & Beyond, Street Easy, and more! We talk about all things Combo: how they came to be, and how they chose the name when their two companies merged, their aspirations, and the state of design present and future. We had a great time talking with them, they're two very thoughtful dudes! Enjoy!

Blunt Business
Incannex Healthcare: Pioneering Combination Medicines and Psychedelic Therapies

Blunt Business

Play Episode Listen Later Dec 3, 2025 32:16 Transcription Available


Blunt Business speaks with Joel Latham, CEO of Incannex Healthcare (NASDAQ: IXHL), a clinical-stage biopharmaceutical company pioneering the use of proprietary combination medicines. Latham breaks down their strategy of fusing synthetic cannabinoids and well-characterized active drug components to target chronic conditions with significant unmet needs, emphasizing a robust intellectual property position and synergistic drug action.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Moriel Ministries
Apologetics by Sandy Simpson | A "New" Combination Teaching

Moriel Ministries

Play Episode Listen Later Dec 2, 2025 39:41


This is a combination of two teachings by Apologist Sandy Simpson. Sandy discusses in back-to-back teachings, New Heresies and the New Indigenous Christian Religion.

The Rise Guys
WEED AND EASTER, A COMBINATION THAT CHANGED THIS DUDE'S LIFE: HOUR ONE

The Rise Guys

Play Episode Listen Later Nov 28, 2025 40:26


BDA: HOCKEY AND SCOTTISH BOOBIES OPEN PHONES: MARSHALL TELLS US A FUNNY STORY ABOUT A TRANS COUPLE OPEN PHONES: I SMOKED WEED ON EASTER AND IT CHANGED MY LIFE ALL ADVICE SHOW: MY SON IS TAKING TWO BIG GIRLS TO PROM

More Than a Pretty Face
Modern Rosacea & Resurfacing: Expert Insights with Dr. Walls & Dr. Boen

More Than a Pretty Face

Play Episode Listen Later Nov 26, 2025 27:54


In this episode of More Than A Pretty Face, Dr. Azi speaks with Dr. Tomi Wall about modern rosacea management, including pulsed-dye lasers, V-Beam, combination treatments, and intradermal Botox for flushing. She then sits down with Dr. Monica Boen to discuss the resurgence of CO₂ and Erbium resurfacing lasers, evolving technology, and the cautious excitement around regenerative treatments like exosomes and PDRN. Both dermatologists share practical skincare advice, treatment philosophy, and their go-to in-office approaches for natural, effective results.  Timeline of what was discussed: 00:00 – Podcast intro & welcome 00:07 – Introducing Dr. Tomi Wall 00:55 – Why rosacea emotionally affects patients 01:40 – Types of rosacea explained 02:35 – Top at-home treatments (azelaic acid, ivermectin, sulfur) 03:40 – In-office vascular treatments with PDL 04:40 – How vascular lasers improve rosacea 05:25 – V-Beam for scarring 06:15 – Best timing to start scar laser treatment 07:15 – Treating bruising immediately after filler 08:10 – V-Beam settings for bruising 09:00 – Botox for flushing & neurovascular mechanisms 10:00 – Dilution, dosing, safety precautions 11:05 – Topicals for temporary redness & rebound effects 12:00 – Rapid-fire questions 13:25 – Close of interview 1 15:25 – Introducing Dr. Boen & her practice 15:55 – Why CO₂ & Erbium ablative lasers are returning 16:35 – What ablative lasers do & why patients accept downtime 17:25 – UltraPulse CO₂ & Erbium for deep resurfacing 18:10 – UltraClear: lighter resurfacing with minimal downtime 19:10 – Choosing mild vs aggressive resurfacing settings 19:55 – Combination treatments (Pico, PDL, Fraxel, Clear & Brilliant) 20:40 – PDRN ("salmon DNA"): buzz vs data 21:40 – Exosomes: potential & regulatory concerns 22:50 – Real complications seen from unregulated injectables 23:35 – Dr. Boen's personal favorite treatments 24:10 – Daily skincare must-haves (SPF, retinoids, antioxidants) 25:00 – LED masks: when they help and when they don't 25:55 – Final message: patient education matters 26:40 – Podcast closing & where to submit questions   ______________________________________________________________ Follow Tomi Wall on Instagram: @dr.tomileewall Dr. Tomi Wall is a laser fellowship–trained, board-certified dermatologist based in Northern California. With advanced training from Harvard Medical School and extensive experience teaching residents at Stanford, she specializes in vascular and laser-based treatments for rosacea, scarring, and inflammatory skin conditions. Dr. Wall is known for her research-informed approach, dedication to patient-centered care, and expertise in combination therapy to achieve natural, evidence-based outcomes.   Follow Monica Boen on Instagram: @drmonicaboen Dr. Monica Boen is a board-certified dermatologist practicing in San Diego with advanced specialization in aesthetic and procedural dermatology. Trained in ablative and regenerative laser surgery, she is recognized for bringing modern innovation to legacy resurfacing technologies such as CO₂ and Erbium lasers. Dr. Boen is known for her comprehensive treatment planning, commitment to clinical safety, and ability to blend multiple modalities for powerful yet natural skin rejuvenation results. ______________________________________________________________ Submit your questions for the podcast to Dr. Azi on Instagram @morethanaprettyfacepodcast, @skinbydrazi, on YouTube, and TikTok @skinbydrazi. Email morethanaprettyfacepodcast@gmail.com. Shop skincare at https://azimdskincare.com and learn more about the practice at https://www.lajollalaserderm.com/ The content of this podcast is for entertainment, educational, and informational purposes and does not constitute formal medical advice. © Azadeh Shirazi, MD FAAD.  

NeurologyLive Mind Moments
154: NEALS 2025: Takeaways That Matter for ALS Care

NeurologyLive Mind Moments

Play Episode Listen Later Nov 14, 2025 27:38


Welcome to the NeurologyLive® Mind Moments® podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. In this episode, "NEALS 2025: Takeaways That Matter for ALS Care," ALS experts Jinsy Andrews, MD, MSc, and James Berry, MD, MPH, reflect on key themes from the 2025 NEALS Annual Meeting, now reintroduced as the Network of Excellence for ALS. They discuss format changes that elevated lightning science, the expanding gene therapy pipeline, and a growing slate of NEALS-affiliated trials. The conversation highlights updates from the HEALEY Platform Trial, the MY-MATCH biomarker-guided precision trial, SOD1 program data, and new antisense and viral vector therapies aimed at sporadic ALS. They also explore the impact of Act for ALS on trial access, the ALL ALS biospecimen repository, and NIH-supported expanded access cohorts. The discussion closes with insights on combination therapy strategies, genetic subtypes, presymptomatic enrollment, and how new collaborations, digital endpoints, and infrastructure advances are shaping momentum heading into 2026. Looking for more Neuromuscular discussion? Check out the NeurologyLive® Neuromuscular clinical focus page. Episode Breakdown: 1:05 – Reflections on meeting highlights and NEALS rebranding into a global network 5:00 – Notable NEALS-affiliated trials and promising new mechanisms in ALS care 12:45 – Combination therapy strategies and future approaches in ALS research 15:20 – Neurology News Minute 18:00 – Expanding clinical trial access for rare and genetic ALS subtypes 22:10 – Building momentum and expectations for the 2026 NEALS Annual Meeting The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: FDA Approves Doxecitine and Doxribtimine Combination Therapy as First Treatment for Thymidine Kinase 2 Deficiency Supplemental New Drug Application Submitted for AXS-05 as Treatment for Alzheimer Disease Agitation BTK Inhibitor Fenebrutinib Meets Primary End Points in Phase 3 Trials for Both Relapsing and Primary Progressive MS  Thanks for listening to the NeurologyLive® Mind Moments® podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.

OncLive® On Air
S14 Ep48: PSMA Theranostics, ctDNA Testing, and Combination Regimens in GU Oncology Spark Conversation at CFS: With Benjamin P. Levy, MD; Scott T. Tagawa, MD, MS, FACP, FASCO

OncLive® On Air

Play Episode Listen Later Nov 13, 2025 26:38


In today's episode, filmed live at the 43rd Annual Chemotherapy Foundation Symposium, lung cancer expert Benjamin P. Levy, MD, hosted a cross-specialty discussion with genitourinary (GU) cancer expert Scott T. Tagawa, MD, MS, FACP, FASCO, about the rapidly evolving treatment paradigms for prostate and kidney cancer. Dr Levy is the clinical director of medical oncology at the Johns Hopkins Sidney Kimmel Cancer Center at Sibley Memorial Hospital and an associate professor of oncology at the Johns Hopkins University School of Medicine in Washington, DC. Dr Tagawa is a professor of medicine and urology at Weill Cornell Medicine, as well as an attending physician at NewYork-Presbyterian – Weill Cornell Medical Center in New York, New York. Their conversation began with a focus on prostate-specific membrane antigen (PSMA)–positive prostate cancer. Dr Tagawa explained that PSMA is a cell surface protein, and that PSMA imaging agents are commonly used to assess biochemical recurrence and perform initial disease staging. He noted that therapy-related adverse effects are often site-specific, including dry mouth/change in taste, and myelosuppression from the radiation payload. For monitoring long-term safety, Dr Tagawa emphasized that renal function must be tracked. Beyond PSMA, other prostate cancer targets include TROP-2, B7-H3, and markers specific to aggressive or neuroendocrine variants, such as DLL3, he reported. In advanced GU cancers, circulating tumor DNA (ctDNA) testing is increasingly important, Dr Tagawa highlighted. In prostate cancer, ctDNA testing is used to assess homologous recombination deficiency (HRD) status and BRCA expression, he said, explaining that evidence for the use of ctDNA testing in GU cancers stems from findings with this type of assay to evaluate minimal residual disease levels in urothelial cancer. He noted that studies show that if patients with urothelial cancer become ctDNA positive within the first year of receiving neoadjuvant chemotherapy, they benefit from treatment with atezolizumab (Tecentriq). Similarly, he stated that patients with previously untreated HRD-positive metastatic prostate cancer also see a progression-free survival benefit when a PARP inhibitor is added to an androgen deprivation therapy/androgen receptor pathway inhibitor backbone. Shifting the conversation to the management of frontline advanced clear cell renal cell carcinoma (RCC), the experts reviewed standard approaches, which involve an immune-oncology (IO) agent plus either a CTLA-4 inhibitor or a VEGF TKI. Tagawa noted that IO/VEGF TKI combinations may be preferred for symptomatic patients needing a rapid response, whereas IO/IO combinations may offer greater potential for treatment cessation. He brought up a key distinction in RCC, which is that re-instituting PD-1/PD-L1 inhibition upon progression in the metastatic setting has generally shown no benefit. Dr Levy brought a broad scope to the GU cancer discussion through his lung cancer expertise, introducing parallels between the treatment paradigms. The interview provided an opportunity to show the importance of creating connections across oncology specialties to bring nuanced perspectives to future advances in clinical research and patient care.

Y.I.E.L.D. Today With Dallin Candland
7 EXTREME Standards for Dallin to Live His BEST Life - #679

Y.I.E.L.D. Today With Dallin Candland

Play Episode Listen Later Nov 11, 2025 30:09


Lots has happened recently. Today I decided once and for all to set some non-negotiables  1. No Phone in My Room - 2. I Move 10,000 Steps Every Day - 3. I Run a Timed Mile Every Thursday - 4. I Listen to a General Conference Talk Every Day - 5. I Study the Scriptures Every Day - 6. I Write for Two Hours a Day -7. I Invest Two Hours Every Monday into a Combination of Cleaning, Planning, and Overall Life Maintenance - Resources Mentioned:"One Percent Better" Talk: https://www.churchofjesuschrist.org/study/general-conference/2021/10/54dunn?lang=eng"Good, Better, Best" Talk: https://www.churchofjesuschrist.org/study/general-conference/2007/10/good-better-best?lang=eng"Where Will This Lead?" Talk: https://www.churchofjesuschrist.org/study/general-conference/2019/04/35oaks?lang=eng"The Power of Spiritual Momentum" Talk: https://www.churchofjesuschrist.org/study/general-conference/2022/04/47nelson?lang=engMore From Me:Subscribe to YIELD Deeply - https://dallincandland.substack.com/Check out my second book, "Patience in These Pages" - https://a.co/d/4kfFqW8Watch the Dallin Candland YouTube channel (for more on the podcast, behind the scenes videos, and more!): https://www.youtube.com/@dallincandlandTime Stamps:Quotes:8:12 - "The battle is against sin, NOT each other."Support the show

Combinate Podcast - Med Device and Pharma
212 - What 6 of the World's Biggest Companies Taught Him About Combination Products

Combinate Podcast - Med Device and Pharma

Play Episode Listen Later Nov 5, 2025 25:42


In this episode of Let's Combinate: Drugs + Devices, host Subhi Saadeh speaks with Leonel Venegas, a seasoned quality and regulatory professional who has worked with global leaders including Alexion, Merck, Johnson & Johnson (Ethicon & Cordis), Amgen, and Medtronic.Leonel shares how integrating Good Laboratory Practices (GLP), Good Clinical Practices (GCP), and Good Pharmacovigilance Practices (GVP) is essential to successful combination-product development. He discusses his journey from chemist to regulatory-affairs expert, uncovering common disconnects between pharma and device cultures, and the critical role of design controls, risk management, and timelines.The conversation also explores GMP and process validation, IDE vs. IND pathways, the challenges of rare-disease programs, and how understanding the cost of quality can reshape testing strategies. Leonel closes by reflecting on becoming a Lean Six Sigma Black Belt and what continuous improvement really looks like in combination-product development.⏱ Timestamps00:00 – Welcome & Introduction00:52 – Integrating GLP, GCP & GMP02:22 – Challenges in Developing Combination Products04:02 – Device-Led Combination Products07:35 – Working with Rare Diseases09:58 – GMP & Process Validation15:08 – Clinical Trials: Drug vs Device19:22 – Cost of Quality & Six Sigma25:12 – Conclusion & Contact InformationLeonel Venegas is the Founder of Precision Regulatory Consulting LLC and an expert in quality and regulatory affairs with over two decades of experience across six global pharma and medtech leaders, including Alexion, Merck, Johnson & Johnson (Ethicon & Cordis), Amgen, and Medtronic.He is certified by ASQ as a CMQ/OE, CQE, CBA, and CSSBB, and holds an M.S. in Regulatory Affairs. Leonel specializes in combination products, medical devices, and IVDs, integrating GLP, GCP, GMP, and GVP principles into complex global development programs.

The John Batchelor Show
41: The Fracture of Reagan's First Marriage, Hollywood's Red Scare, and the Appearance of Nancy Davis. Max Boot discusses the marriage between Ronald Reagan and Jane Wyman, which was considered an "odd combination." Wyman was drawn to Reagan b

The John Batchelor Show

Play Episode Listen Later Nov 3, 2025 10:17


The Fracture of Reagan's First Marriage, Hollywood's Red Scare, and the Appearance of Nancy Davis. Max Boot discusses the marriage between Ronald Reagan and Jane Wyman, which was considered an "odd combination." Wyman was drawn to Reagan because he was a "nice guy" and a "white knight," though Reagan was "very hard to get to commit." By the eve of World War II, Reagan was professionally ascending, but the war derailed his commercial film career as he spent the entire conflict in Hollywood making training and propaganda films. When the war ended, there was diminished demand for his services, while Jane Wyman's career soared after the war. Reagan became increasingly active in the Screen Actors Guild (SAG) and Hollywood politics, still an "idealistic liberal" and New Dealer, while Wyman became uninterested in politics, leading them to drift apart. The political climate was dominated by Congress's search for communists in Hollywood. Reagan served as the unpaid president of SAG and navigated the "treacherous politics" of the McCarthy era skillfully, appearing liberal when testifying before HUAC while quietly acting as an FBI informant. Jane Wyman initiated the divorce in 1948, shocking Reagan and leaving him adrift. Nancy Davis then entered his life, leading to a marriage that made sense, as Nancy wanted to be a wife and mother and threw herself into the role of the "perfect wife." Reagan needed a strong woman, and Nancy became absolutely integral to his career advancement, acting as a shrewd political figure who often handled hiring and firing.

Combinate Podcast - Med Device and Pharma
211 - Inside FDA's Office of Combination Products: History, PMOA, and What's Next for Combination Products with Mark Kramer

Combinate Podcast - Med Device and Pharma

Play Episode Listen Later Oct 30, 2025 46:24


In this episode of Let's Combinate: Drugs + Devices, host Subhi Saadeh welcomes Mark Kramer, the founding director of FDA's Office of Combination Products (OCP). Mark takes us on a deep dive into the history of how combination products have been regulated in the U.S., starting with the Safe Medical Devices Act of 1990 and how the process evolved into the formation of OCP in 2002.We explore questions such as: What challenges did industry and the FDA face in the early days of combination products? How did the “Request for Designation” process come about, and how is regulatory identity determined? What is the “Primary Mode of Action” (PMOA) rule and why does it matter? How do user fees, cross-center coordination, and post-market regulations shape how combination products get to market and are monitored? Mark also highlights current regulatory gapssuch as cross-labeling and site registration issues that continue to impact developers.Whether you're working in med-tech, pharma, or regulatory affairs, this episode offers historical perspective, technical insights, and strategic take-aways for navigating the combination-product space. Tune in for a candid conversation with one of the leading figures in this field.Timestamps:00:00 Introduction & Guest Welcome00:35 Historical Background of Combination Products03:05 Creation of Office of Combination Products (OCP)04:29 Early Challenges and Developments04:54 MDUFA, PDUFA, User Fee Programs & Legislative Impact14:24 Defining Primary Mode of Action (PMOA)18:35 OCP's Role & Responsibilities26:49 Industry Adoption & Challenges38:48 Regulatory Gaps & Future Directions46:00 Conclusion & Contact InformationContact & Resources:Connect with Mark Kramer on LinkedIn or via email at Mark.Kramer@greenleafhealth.comMark Kramer is Principal of the Medical Devices & Combination Products regulatory practice at Eliquent Life Sciences (formerly Greenleaf Health). He has more than 35 years experience at FDA and in regulated industry. At FDA, he established and directed the Office of Combination Products and was a scientific reviewer and later supervisor of the premarket review of devices in a variety of medical discipline areas. Following his FDA career, he served as Regulatory Affairs Executive and Chief Regulatory Strategist at GE Healthcare and then as an independent regulatory consultant for over 10 years before joining Greenleaf. Mark served as a board member of the Regulatory Affairs Professionals Society (RAPS) and in 2021, he was awarded the RAPS Founders Award, the profession's highest honor, recognizing exemplary regulatory professionals who have shaped regulatory policy and practice and have made a positive impact on the profession.Subhi Saadeh is a Quality Professional and host of Let's Combinate. With a background in Quality, Manufacturing Operations and R&D he's worked in Large Medical Device/Pharma organizations to support the development and launch of Hardware Devices, Disposable Devices, and Combination Products for Vaccines, Generics, and Biologics. Subhi serves currently as the International Committee Chair for the Combination Products Coalition(CPC) and as a member of ASTM Committee E55 and also served as a committee member on AAMI's Combination Products Committee.For questions, inquiries or suggestions please reach out at letscombinate.com or on the show's LinkedIn Page.

3 Martini Lunch
China's Chilling Combination of AI & Genetic Engineering

3 Martini Lunch

Play Episode Listen Later Oct 29, 2025 29:10 Transcription Available


Join Jim and Greg for the Wednesday 3 Martini Lunch as they dig into the Democrats' hilariously bad messaging on the government shutdown, China's chilling fusion of AI and genetic engineering, and Jon Stewart's absurd comparison of Zohran Mamdani to Jackie Robinson.First, they marvel at how Democrats proudly admit to causing real pain for Americans in an attempt to gain political leverage in the shutdown fight. It's a cold, heartless message but Democrats are more than welcome to keep using it.Next, Jim shares insights from Bill Drexel of the Hudson Institute, who joined Jim on the recent trip to India. Drexel reports that China is combining artificial intelligence with genetic engineering in pursuit of future generations with no flaws and who will be superior soldiers. Jim also explains how the ethical nightmare surrounding this plan won't even matter to Xi Xinping and the Chinese Communist Party.Finally, they roll their eyes as Jon Stewart of The Daily Show fawns over Democrat New York City mayoral nominee Zohran Mamdani and compares him to legendary baseball player Jackie Robinson. Jim and Greg document how the Democrats have shifted from running away from Mamdani to a full embrace once they sensed he could win.Please visit our great sponsors:Cancel unwanted subscriptions and reach your financial goals faster with Rocket Money at https://RocketMoney.com/MARTINI Build your fall sanctuary of comfort with Boll and Branch. Save 20% plus free shipping on your first set of sheets at https://BollAndBranch.com/THREEMARTINI —offer ends soon, exclusions apply.

The Ricochet Audio Network Superfeed
Three Martini Lunch: China's Chilling Combination of AI & Genetic Engineering

The Ricochet Audio Network Superfeed

Play Episode Listen Later Oct 29, 2025 29:10


Join Jim and Greg for the Wednesday 3 Martini Lunch as they dig into the Democrats' hilariously bad messaging on the government shutdown, China's chilling fusion of AI and genetic engineering, and Jon Stewart's absurd comparison of Zohran Mamdani to Jackie Robinson. First, they marvel at how Democrats proudly admit to causing real pain for […]

KONCRETE Podcast
#343 - They're Wrong about Cold Exposure: How to Really Supercharge Your Body | Dr. Thomas Seager

KONCRETE Podcast

Play Episode Listen Later Oct 24, 2025 166:18


Watch every episode ad-free & uncensored on Patreon: https://patreon.com/dannyjones Thomas Seager, PhD is CEO of Morozko Forge ice bath company. He is also Associate Professor in the School of Sustainable Engineering & the Built Environment at Arizona State University. He's authored two books - "Uncommon Cold: The Science & Experience of Cold Plunge Therapy" & "Uncommon Testosterone: Cold Plunge Therapy for Optimizing Sexual Health." SPONSORS https://whiterabbitenergy.com/?ref=DJP - Use code DJP for 20% off EPISODE LINKS https://www.morozkoforge.com Uncommon Testosterone Book: https://a.co/d/6eUuE9j Uncommon Cold Book: https://bit.ly/3L7O4MU https://www.instagram.com/seagertp https://x.com/seagertp FOLLOW DANNY JONES https://www.instagram.com/dannyjones https://twitter.com/jonesdanny OUTLINE 00:00 - Pre-cooling vs. post-cooling with ice baths 15:11 - Ice baths are replacing TRT 25:24 - Best length of a cold plunge 30:10 - When ice baths went mainstream 40:04 - Mitochondrial health, brown fat & cold exposure 46:04 - How the mitochondria emit visible light 55:59 - UVA vs. UVB light 01:02:32 - How often you should cold plunge 01:08:57 - Combination of sauna & cold plunge 01:17:44 - How the body survives a fast 01:25:21 - Best cure for headaches & migraines 01:37:30 - Seed oils, food dyes & sugar 01:50:27 - Why RFK is perfect for HHS 01:57:52 - How to fix nutrition in poor populations 02:05:29 - What REALLY causes autism in kids 02:14:28 - Insurance incentives for hospitals 02:22:13 - New pharmaceutical ad requirements 02:32:01 - Hot tubs make you sick Learn more about your ad choices. Visit podcastchoices.com/adchoices

AMA Marketing / And with Bennie F. Johnson
The combination of behavioral science and marketing

AMA Marketing / And with Bennie F. Johnson

Play Episode Listen Later Oct 22, 2025 43:30


Nancy Harhut, Founder of HBT Marketing, joins AMA's CEO and podcast host, Bennie F. Johnson, for a conversation about the misconceptions of B2B marketing, what happens when you employ behavioral science in marketing campaigns, and why it's always necessary to employ the brain.

Freely Filtered, a NephJC Podcast
FF 83 CONVINCE: Can We Start Flozins and Finerenone Simultaneously?

Freely Filtered, a NephJC Podcast

Play Episode Listen Later Oct 21, 2025 89:10


The FiltrateJoel Topf @kidneyboy.bsky.social‬Swapnil Hiremath @hswapnil.medsky.socialNayan Arora captainchloride.bsky.socialSopia Ambruso @sophia-kidney.bsky.socialSpecial Guests Brendon Neuen @brendonneuen.bsky.social Associate Professor and Program Lead, Renal and Metabolic at The George Institute for Global Health. Nephrologist and Director of Kidney Trials at Royal North Shore Hospital.Neuen has had three prior appearances on Freely Filtered: EMPA Kidney, DUPLEX and Sparsentan in FSGS, FLOW and SemaglutideMuthiah Vaduganathan @mvaduganathan on X. Cardiologist at Brigham and Women's Hospital and Harvard Medical School. Assistant Professor of Medicine.Editing byJoel TopfThe Kidney Connection written and performed by Tim YauShow NotesDONATE to NephJC! Finerenone with Empagliflozin in Chronic Kidney Disease and Type 2 Diabetes NEJM | NephJC SummaryFIDELIO Bakris et al, NEJM 2020 | NephJC Summary; subgroup throws doubt on efficacy of finerenone in patients on flozinsFIGARO Pitt et al, NEJM 2021; subgroups clearly shows finerenone works, flozins or notNEJM editorial (wrongly) saying do not use Flozins unless on RASi Don't use dual RAS blockade ONTARGET Yusuf et al, NEJM 2008; VA NEPHRON-D Fried et al NEJM 2013Why we cannot study finerenone in HFrEF (RALES Pitt et al NEJM 1999) Muthu is jealous of GFR slope and albuminuria surrogate endpoints and wants to borrow them for HFpEF (Inker et al EHJ 2025)Combination therapy and CV outcomes in hypertension (Wang et al JAMA Card 2024 on low dose combinations and BP; Egan et al Blood Pressure 2022 review of topic) CONFIRMATION HF trial registry entry (Finerenone and Empagliflozin in hospitalized patients with HF)23:20: Nayan and Swap miss a chance to say ‘de-flozination' to discuss stopping a flozin which would allow a patient to be included in the trial Finerenone is a CYP3A4 substrate (Heinig et al Clin Pharmacokinetics 2023); Useful list of CYP3A4 inducers and inhibitors Everyone should get an ABPM (Bugeja et al CMAJ 2022)EASiKIDNEY study design Albuminuria mediates CKD benefits with Finerenone (Agarwal et al Ann Intern Med 2023)GFR slope and Albuminuria and the FDA (Taylor et al eClin Med 2025) Dapagliflozin and Eplerenone combination crossover trial (Provenzano et al JASN 2022)Joel gets promoted! (PBFluids reflection) Bluesky NephJC Chat discussion on ‘renal remission' Withdrawal of Finerenone and worse outcomes from FINEARTS (Vaduganathan et al JACC 2025)Combination therapies Analysis from Brendan and Muthu (Neuen et al Circulation 2024)Do not use KFRE when GFR > 60 (KDIGO Practice Point 2.2.4: Note that risk prediction equations developed for use in people with CKD G3–G5, may not be valid for use in those with CKD G1–G2) Finerenone vs Spironolactone trial in Primary Aldosteronism (Hu et al Circulation 2025)FIND CKD trial design (Heerspink et al NDT 2025) FINE-ONE trial design (Heerspink et al Diab Res Practice 2023) Tubular SecretionsNayan keeping his chin up as Yankees lose and Mariners follow (MLB Playoffs)Sophia's adventures with Beekeeping (Royal Jelly?) Brendon loves listening to ‘Susan' by Raye Muthu is back into Taekwondo Swap is still reading Martha Wells (Witch King on GoodReads)Joel will be hiking the Laugavegur trail in Iceland

Research To Practice | Oncology Videos
Non-Small Cell Lung Cancer — 5-Minute Journal Club Issue 3 with Dr Aaron Lisberg: Defining the Role of TROP2-Directed Antibody-Drug Conjugates

Research To Practice | Oncology Videos

Play Episode Listen Later Oct 20, 2025 24:48


Featuring an interview with Dr Aaron Lisberg, including the following topics: Efficacy and Safety of Datopotamab Deruxtecan (Dato-DXd) for Patients with Previously Treated EGFR-Mutated Advanced Non-Small Cell Lung Cancer (NSCLC): A Pooled Analysis of the TROPION-Lung01 and TROPION-Lung05 Trials (0:00) Ahn M-J et al. Efficacy and safety of datopotamab deruxtecan (Dato-DXd) in patients (pts) with previously-treated EGFR-mutated advanced non-small cell lung cancer (NSCLC): A pooled analysis of TROPION-Lung01 and TROPION-Lung05. ESMO Asia 2024;Abstract LBA7 Ahn M-J et al. A pooled analysis of datopotamab deruxtecan in patients with EGFR-mutated NSCLC. J Thorac Oncol 2025;[Online ahead of print]. Abstract Sacituzumab Tirumotecan for Previously Treated Advanced EGFR-Mutated NSCLC: Results from the Randomized OptiTROP-Lung03 Study (7:08) Fang W et al. Sacituzumab tirumotecan versus docetaxel for previously treated EGFR-mutated advanced non-small cell lung cancer: Multicentre, open label, randomised controlled trial. BMJ 2025;389:e085680. Abstract Zhang L et al. Sacituzumab tirumotecan (sac-TMT) in patients (pts) with previously treated advanced EGFR-mutated non-small cell lung cancer (NSCLC): Results from the randomized OptiTROP-Lung03 study. ASCO 2025;Abstract 8507. Combination of Dato-DXd and Immunotherapy as First-Line Therapy for Patients with Advanced NSCLC (13:12) Cuppens K et al. First-line (1L) datopotamab deruxtecan (Dato-DXd) + durvalumab ± carboplatin in advanced or metastatic non-small cell lung cancer (a/mNSCLC): Results from TROPION-Lung04 (cohorts 2 and 4). ESMO Targeted Anticancer Therapies Congress 2025;Abstract 8O. Okamoto I et al. TROPION-Lung07: Phase III study of Dato-DXd + pembrolizumab ± platinum-based chemotherapy as 1L therapy for advanced non-small-cell lung cancer. Future Oncol 2024;20(37):2927-36. Abstract Levy BP et al. TROPION-Lung08: Phase III study of datopotamab deruxtecan plus pembrolizumab as first-line therapy for advanced NSCLC. Future Oncol 2023;19(21):1461-72. Abstract Aggarwal C et al. AVANZAR: Phase III study of datopotamab deruxtecan (Dato-DXd) + durvalumab + carboplatin as 1L treatment of advanced/mNSCLC. World Conference on Lung Cancer (WCLC) 2023;Abstract P2.04-02. TROP2-Targeting Antibody-Drug Conjugates as Neoadjuvant and/or Adjuvant Therapy for Patients with Resectable NSCLC (19:08) A phase III, randomised, open-label, global study of adjuvant datopotamab deruxtecan (Dato-DXd) in combination with rilvegostomig or rilvegostomig monotherapy versus standard of care, following complete tumour resection, in participants with Stage I adenocarcinoma non-small cell lung cancer who are ctDNA-positive or have high-risk pathological features (TROPION-Lung12). NCT06564844 Cascone T et al. Perioperative durvalumab plus chemotherapy plus new agents for resectable non-small-cell lung cancer: The platform phase 2 NeoCOAST-2 trial. Nat Med 2025;31(8):2788-96. Abstract CME information and select publications

Daily Radio Program with Charles Stanley - In Touch Ministries
A Winning Combination in Time of Need - Part 2

Daily Radio Program with Charles Stanley - In Touch Ministries

Play Episode Listen Later Oct 14, 2025 19:48


Keep your focus on God and pray with faith, knowing He will answer your petitions.See omnystudio.com/listener for privacy information.

Daily Radio Program with Charles Stanley - In Touch Ministries
A Winning Combination in Time of Need - Part 2

Daily Radio Program with Charles Stanley - In Touch Ministries

Play Episode Listen Later Oct 14, 2025


Keep your focus on God and pray with faith, knowing He will answer your petitions.

Daily Radio Program with Charles Stanley - In Touch Ministries
A Winning Combination in Time of Need - Part 1

Daily Radio Program with Charles Stanley - In Touch Ministries

Play Episode Listen Later Oct 13, 2025 19:18


Write down your prayer requests to better focus your mind and pray in detail.See omnystudio.com/listener for privacy information.

Daily Radio Program with Charles Stanley - In Touch Ministries
A Winning Combination in Time of Need - Part 1

Daily Radio Program with Charles Stanley - In Touch Ministries

Play Episode Listen Later Oct 13, 2025


Write down your prayer requests to better focus your mind and pray in detail.

Answers with Ken Ham
A Combination of Traits

Answers with Ken Ham

Play Episode Listen Later Oct 3, 2025


Flight is an incredibly complex process that involves a combination of unique traits in birds all working together.

Wealth Warehouse
Episode 190: Infinite Banking and Pheasant Hunting--the Perfect Combination

Wealth Warehouse

Play Episode Listen Later Sep 29, 2025 28:53


Visit our website:https://www.thewealthwarehousepodcast.com/Fresh off the annual South Dakota pheasant trip, Dave and Paul unpack how time in the field mirrors smart money habits. From planning that survives “first contact,” to keeping dry powder ready so you can seize opportunities, to teaching kids stewardship and building legacy, this episode ties hunting camp lessons directly to the Infinite Banking Concept (IBC). Expect talk on independence, autonomy, privacy, patience & timing, and why liquidity you control beats balances that just “look good on paper.”Becoming Your Own Banker by Nelson Nash:https://infinitebanking.org/product/becoming-your-own-banker/ref/46/Episode Highlights:0:00 - Teaser & open2:17 - The crew: annual trip, fellowship, and why like-minded matters3:38 - How the hunt parallels IBC4:52 - Healthy disagreements (Bitcoin, moon landing) + shared values6:22 - The common thread7:00 - Independence, autonomy, privacy & healthy skepticism8:39 - Legacy and making memories with your kids9:31 - Planning meets reality12:00 - Translating hiccups to IBC13:16 - Patience & timing14:23 - Loaded shotgun vs. locked-up 401(k) liquidity15:53 - Fancy gear vs. dry powder16:34 - Getting better each year = older policies perform better17:24 - Stewardship and teaching the next generation18:02 - Accessing capital without interrupting growth22:02 - Save 30% rule: habits that build wealth22:32 - Seeking independence from commercial banking23:50 - Why IBC contributors may fuel less inflation24:57 - Hunters' autonomy as a money mindset28:27 - Episode wrap-upABOUT YOUR HOSTS:David Befort and Paul Fugere are the hosts of the Wealth Warehouse Podcast. David is the Founder/CEO of Max Performance Financial. He founded the company with the mission of educating people on the truths about money.David's mission is to show you how you can control your own money, earn guarantees, grow it tax-free, and maintain penalty-free access to it to leverage for opportunities that will provide passive income for the rest of your life.Paul, on the other hand, is an Active Duty U.S. Army officer who graduated from Norwich University in 2002 with a B.A. in History and again in 2012 with a M.A. in Diplomacy and International Terrorism. Paul met his wife Tammy at Norwich.As a family, they enjoy boating, traveling, sports, hunting, automobiles, and are self-proclaimed food people.Visit our website:https://www.thewealthwarehousepodcast.com/Catch up with David and Paul, visit the links below!Website: https://infinitebanking.org/agents/Fugere494 https://infinitebanking.org/agents/Befort399LinkedIn: https://www.linkedin.com/in/david-a-befort-jr-09663972/ https://www.linkedin.com/in/paul-fugere-762021b0/Email:davidandpaul@theibcguys.com

Heal Yourself. Change Your Life
305: Finding the Self-Healing Formula: Unlocking the Hidden Combination for Mind-Body Healing

Heal Yourself. Change Your Life

Play Episode Listen Later Sep 5, 2025 77:28


In this powerful episode, Brandy reveals one of the most profound discoveries in mind-body healing: there's actually a formula for healing. You'll hear a live coaching session with a beautiful volunteer where hidden emotional patterns are uncovered and shifted in real time—leading to relief, new awareness, and genuine empowerment. One of the most eye-opening insights is seeing how different combinations of emotions affect the body in different ways—and how key it is to shift the mindset at a deeper, subconscious level for lasting results in both emotional healing and physical health. You'll discover: Why stress alone isn't the real cause—and what's actually happening  How guilt, perfectionism, and fear of rejection combine to affect the body What “reverse emotional processing” is and why it makes change possible A moving live demonstration of emotions shifting into freedom How to begin applying these self-healing techniques to your own journey This session is a powerful reminder of the mind-body connection and how, when we truly learn to work with our minds, we can unlock natural healing and transformation. If you've ever struggled with chronic health challenges, emotional blocks, or guilt that weighs you down, this episode will inspire you to see what's possible. Tune in and discover how much power you truly have when you learn to decode what your body is trying to tell you.   Disclaimer: This podcast is for educational purposes only and is not a substitute for psychiatric or medical care. If you struggle with negative thoughts, chronic pain, or chronic health issues, please continue seeing your doctor as recommended. Think of self-healing and mind-body healing as ways to partner with your doctor—keeping them informed and working as a team—so you can feel empowered in your health journey and fully embrace what's possible through the power of your mind, emotions, and energy. Genuine change and consistent follow-through are key. Please enjoy this self-healing podcast. IMPORTANT NOTE: We understand that some may believe mind-body healing is impossible. Therefore, if you would like to see images of individuals using their minds to relieve pain, you can check out this medical journal. It includes images from some of Brandy's case studies. If you want to learn how to use your mind to heal yourself, you can check out the training on Brandy's website. Each week, Brandy publishes a volunteer episode where she coaches a volunteer to heal themselves using their own mind. In addition, Brandy shares a quick IQ episode (Insights and Questions) where she answers listener questions or delves deeper into insights on working with the mind for healing. Additional links and resources: Click here to begin "Finding the GIFT in Self-Healing™" https://brandygillmore.com/healing Join the FREE Breakthrough 90-Minute "GIFT Mind-Body Healing™ Masterclass" Training: https://brandygillmore.com/gift-mind-body-healing-masterclass The GIFT Method™ Online Video Series: Heal Yourself. Change Your Life. https://brandygillmore.com/gift-method-healing Website: https://brandygillmore.com TEDx Talk: https://brandygillmore.com/tedx Social Media and Additional: Facebook: https://facebook.com/brandy.gillmore/ IG: https://www.instagram.com/brandygillmore/ X ~ (Twitter): https://twitter.com/BrandyGillmore Additional classes and services: Heal & Transform Your Self-Love and Relationships with GIFT Alternative Therapy and Mind-Reprogramming (GIFT ATMR)™:  https://brandygillmore.com/gift-atmr Gillmore Internal Freedom Technique (GIFT)® : https://brandygillmore.com/gillmore-internal-freedom-technique/ Additional Courses: https://brandygillmore.com/courses-workshops VIP Monthly Coaching https://brandygillmore.com/vip-coaching/ Please remember that genuine change and follow through are key for self-healing results. If you struggle with negative thoughts or have a chronic health issue or chronic pain, please do not avoid seeing your doctor. Instead, your goal with self-healing should be to continue to see your doctor as recommended and blow their mind with what you are capable of with your mind and with the power of mind-body healing. Please enjoy this self-healing podcast. Topics: relationship healing, how to improve relationships, emotional triggers in relationships, mind-body connection, creating love and connection, relationship advice for healing, practical relationship tips, energy in relationships, healing relationships with mindset, stop relationship patterns, mind-based relationship tools, relationship transformation tips, Brandy Gillmore, Brandy Gillmore relationship advice, self-healing and relationships, communication in relationships, improve relationship connection, relationship mindfulness, break negative relationship cycles

Unf*cking The Republic
The Fed, Tariffs & Big Beautiful “Sequel.” The 3 Punch Combination to Knockout the American People.

Unf*cking The Republic

Play Episode Listen Later Sep 1, 2025 48:17


The U.S. is running out of options to service the national debt. Secretary Bessent announced that we will now use revenue from tariffs to pay down budget deficits, rather than reinvest them into the economy. Some are treating this as welcome news. At the same time, the GOP has formed a working group to draft up a “sequel” to the Big Beautiful Bill to deepen cuts to Medicaid and federal student aid. They’ll do anything other than raise taxes on those that can afford them. But tariffs and more cuts to vital programs will only hasten economic decline, so team Trump is running out of options to stop the bleeding. And that means only one thing: Printing more money. But that’s more complicated than it seems and will lead to disastrous results. It does explain, however, why Trump is so desperate to take over the Federal Reserve. Chapters Intro: 00:00:57 Post Show Musings: 00:32:55 Outro: 00:47:04 Resources UNFTR.com Sign the Petition To Stop the Senate From Passing These Bills Politico: House Republicans want another megabill. One GOP senator says it could be ‘damaging.’ X: Republican Study Committee Republican Study Committee: One Big Beautiful Sequel: RSC Chairman Launches Working Group for Second Reconciliation Bill Brookings: What is the repo market, and why does it matter? St. Louis Fed: What Is Yield Curve Control? Treasury: Treasury Announces Marketable Borrowing Estimates UNFTR Quickies UNFTR Discord -- If you like #UNFTR, please leave us a rating and review on Apple Podcasts and Spotify: unftr.com/rate and follow us on Facebook, Bluesky, TikTok and Instagram at @UNFTRpod. Visit us online at unftr.com. Join our Discord at unftr.com/discord. Become a member at unftr.com/memberships. Buy yourself some Unf*cking Coffee at shop.unftr.com. Visit our bookshop.org page at bookshop.org/shop/UNFTRpod to find the full UNFTR book list, and find book recommendations from our Unf*ckers at bookshop.org/lists/unf-cker-book-recommendations. Access the UNFTR Musicless feed by following the instructions at unftr.com/accessibility. Unf*cking the Republic is produced by 99 and engineered by Manny Faces Media (mannyfacesmedia.com). Original music is by Tom McGovern (tommcgovern.com). The show is hosted by Max and distributed by 99.Support the show: https://www.unftr.com/membershipsSee omnystudio.com/listener for privacy information.