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Interview with Christian S. Hendershot, PhD, and Klara R. Klein, MD, PhD, authors of Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial. Hosted by John Torous, MD. Related Content: Once-Weekly Semaglutide in Adults With Alcohol Use Disorder Semaglutide Shows Promise in Reducing Alcohol Cravings
PsychopharmaPearls is NEI's focused podcast series highlighting the clinical insights that can sharpen your prescribing decisions. In this episode, Dr. Andy Cutler talks with Dr. Lisa Harding about how to choose between IV ketamine and intranasal esketamine for patients with difficult-to-treat depression. They unpack the differences that truly matter in practice—from patient selection and monitoring to access, cost, and common missteps. Tune in for practical pearls you can immediately apply to select the right treatment for the right patient. Lisa Harding, MD is a board-certified psychiatrist and nationally recognized depression specialist with deep expertise in interventional psychiatry. She has performed more than 4,000 procedures, including electroconvulsive therapy (ECT), intravenous ketamine, intranasal esketamine, and transcranial magnetic stimulation (TMS). Dr. Harding is known for her thoughtful approach to complex, treatment-resistant depression, integrating advanced somatic therapies, psychopharmacology, and psychotherapy. She serves as an Assistant Clinical Professor of Psychiatry at Yale University in New Haven, Connecticut. Andrew J. Cutler, MD is a leading psychiatrist, psychopharmacology expert, and clinical researcher with decades of experience in CNS drug development. As Chief Medical Officer of Neuroscience Education Institute and EMA Wellness, he brings frontline clinical insight together with deep knowledge of the evidence base. Dr. Cutler is widely recognized for translating research into practical guidance for everyday practice and serves as a Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Resources Sanacora G et al. A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders. JAMA Psychiatry 2017;74(4):399-405. doi:10.1001/jamapsychiatry.2017.0080 McIntyre RS et al. Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation. Am J Psychiatry 2021;178(5):383-399. doi:10.1176/appi.ajp.2020.20081251 Save $100 on registration for 2026 NEI Spring Congress with code NEIPOD26 Register today at nei.global/spring Never miss an episode!
Psychedelics are having a cultural moment. Research is promising. Stories of healing are everywhere. But here's the truth: these experiences aren't magic cures. And they aren't right for every nervous system at every time. In this episode, Elisabeth Kristof and Jennifer Wallace slow the conversation down. Instead of asking, "Do psychedelics heal trauma?" They explore a more grounded question: What becomes possible when psychedelic or peak somatic experiences are approached through the lens of nervous system safety, preparation, and integration? If you've been curious about psychedelics, already had experiences, or feel unsure whether they're right for you, this episode offers nuance, research, and deep nervous system perspective. Because post-traumatic growth isn't about becoming someone new. It's about becoming more available to the life that's already waiting for you. Topic Covered Why psychedelics may reorganize meaning, not just reduce symptoms How trauma fragments narrative and how safety allows integration The science of psychological flexibility and why it predicts long-term outcomes What "somatic journeying" is and why it can feel disorienting The importance of preparation, titration, and facilitator trust Why intensity does not equal healing Psychedelics vs antidepressants in research on connectedness Default Mode Network (DMN), identity rigidity, and belief updating Why creativity often emerges when survival softens The risks of over-reliance and "chasing the medicine" Why discernment and self-trust matter more than hype Chapters 00:00 – Psychedelics Aren't Magic Cures 03:00 – Meaning-Making & Narrative Reorganization 08:58 – Psychological Flexibility & Emotional Capacity 17:00 – Preparation, Somatic Journeying & Integration 23:29 – Connectedness & Relational Repair 34:33 – Identity, Neuro Tags & the Default Mode Network 41:03 – Creativity as a Byproduct of Safety 48:14 – Discernment, Industry Hype & Self-Trust Calls to Action: Neurosomatic Intelligence is now enrolling : https://neurosomaticintelligence.com/nsi-certification Sacred Synapse: an educational YouTube channel founded by Jennifer Wallace that explores nervous system regulation, applied neuroscience, consciousness, and psychedelic preparation and integration through Neurosomatic Intelligence. Wayfinder Journal: Track nervous system patterns and support preparation and integration through Neurosomatic Intelligence. FREE 1 Year Supply of Vitamin D + 5 Travel Packs from Athletic Greens when you use my exclusive offer: https://www.drinkag1.com/rewired Learn to work with Boundaries at the level of the body and nervous system at https://www.boundaryrewire.com Get a two-week free trial of neurosomatic training at https://rewiretrial.com Sources: Amada, N., et al. "The Transformative Potential of Psychedelic Experiences: A Qualitative Analysis of Meaning-Making and Narrative Reorganization." Journal of Consciousness Studies, vol. 27, no. 7–8, 2020, pp. 122–150. Carhart-Harris, Robin L., et al. "Neural Correlates of the Psychedelic State as Determined by fMRI Studies with Psilocybin." Proceedings of the National Academy of Sciences, vol. 109, no. 6, 2012, pp. 2138–2143. Carhart-Harris, Robin L., et al. "The Entropic Brain: A Theory of Conscious States Informed by Neuroimaging Research with Psychedelic Drugs." Frontiers in Human Neuroscience, vol. 8, 2014, article 20. Carhart-Harris, Robin L., et al. "Psilocybin with Psychological Support for Treatment-Resistant Depression: Six-Month Follow-Up." Psychopharmacology, vol. 235, no. 2, 2018, pp. 399–408. Davis, Alan K., Roland R. Griffiths, and Frederick S. Barrett. "Psychological Flexibility Mediates the Relations between Acute Psychedelic Effects and Subjective Decreases in Depression and Anxiety." Journal of Contextual Behavioral Science, vol. 15, 2020, pp. 39–45. Davis, Alan K., et al. "Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial." JAMA Psychiatry, vol. 78, no. 5, 2021, pp. 481–489. Erritzoe, David, et al. "Effects of Psilocybin Therapy versus Escitalopram on Depression and Emotional Connectedness in Major Depressive Disorder." The New England Journal of Medicine, vol. 384, 2021, pp. 1402–1411. Griffiths, Roland R., et al. "Psilocybin Produces Substantial and Sustained Decreases in Depression and Anxiety in Patients with Life-Threatening Cancer: A Randomized Double-Blind Trial." Journal of Psychopharmacology, vol. 30, no. 12, 2016, pp. 1181–1197. MacLean, Katherine A., Matthew W. Johnson, and Roland R. Griffiths. "Mystical Experiences Occasioned by the Hallucinogen Psilocybin Lead to Increases in the Personality Domain of Openness." Journal of Psychopharmacology, vol. 25, no. 11, 2011, pp. 1453–1461. Watts, Rosalind, et al. "Patients' Accounts of Increased 'Connectedness' and 'Acceptance' after Psilocybin for Treatment-Resistant Depression." Journal of Humanistic Psychology, vol. 57, no. 5, 2017, pp. 520–564. Weiss, B., et al. "Associations between Naturalistic Psychedelic Use, Psychological Insight, and Changes in Social Connectedness and Personality." Frontiers in Psychology, vol. 12, 2021, article 667987. Disclaimer: Trauma Rewired podcast is intended to educate and inform but does not constitute medical, psychological or other professional advice or services. Always consult a qualified medical professional about your specific circumstances before making any decisions based on what you hear. We share our experiences, explore trauma, physical reactions, mental health and disease. If you become distressed by our content, please stop listening and seek professional support when needed. Do not continue to listen if the conversations are having a negative impact on your health and well-being. If you or someone you know is struggling with their mental health, or in mental health crisis and you are in the United States you can 988 Suicide and Crisis Lifeline. If someone's life is in danger, immediately call 911. We do our best to stay current in research, but older episodes are always available. We don't warrant or guarantee that this podcast contains complete, accurate or up-to-date information. It's very important to talk to a medical professional about your individual needs, as we aren't responsible for any actions you take based on the information you hear in this podcast. We invite guests onto the podcast. Please note that we don't verify the accuracy of their statements. Our organization does not endorse third-party content and the views of our guests do not necessarily represent the views of our organization. We talk about general neuro-science and nervous system health, but you are unique. These are conversations for a wide audience. They are general recommendations and you are always advised to seek personal care for your unique outputs, trauma and needs. We are not doctors or licensed medical professionals. We are certified neuro-somatic practitioners and nervous system health/embodiment coaches. We are not your doctor or medical professional and do not know you and your unique nervous system. This podcast is not a replacement for working with a professional. The BrainBased.com site and RewireTrial.com is a membership site for general nervous system health, somatic processing and stress processing. It is not a substitute for medical care or the appropriate solution for anyone in a mental health crisis. Any examples mentioned in this podcast are for illustration purposes only. If they are based on real events, names have been changed to protect the identities of those involved. We've done our best to ensure our podcast respects the intellectual property rights of others, however if you have an issue with our content, please let us know by emailing us at traumarewired@gmail.com. All rights in our content are reserved.
Interview with Christian A. Webb, PhD, author of Predicting Adolescent Response to School-Based Mindfulness: A Secondary Analysis of the MYRIAD Trial. Hosted by John Torous, MD. Related Content: Predicting Adolescent Response to School-Based Mindfulness
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-470 Overview: Social media use is nearly ubiquitous among adolescents, raising concern about its role in rising rates of depression, anxiety, insomnia, and suicidality. Although prior evidence has been mixed, emerging studies offer new insights on the relationship between social media use and adolescent mental health. Join us as we review current literature and discuss potential strategies to mitigate negative impacts and improve outcomes. Episode resource links: Calvert E, Cipriani M, Dwyer B, et al. Social Media Detox and Youth Mental Health. JAMA Netw Open. 2025;8(11):e2545245. doi:10.1001/jamanetworkopen.2025.45245 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2840489 Clayborne ZM, Capaldi CA, Mehra VM. Associations between digital media use behaviours, screen time and positive mental health in youth: results from the 2019 Canadian Health Survey on Children and Youth. BMC Public Health. 2025;25(1):2303. Published 2025 Jul 3. doi:10.1186/s12889-025-22874-2 Grøntved A, Singhammer J, Froberg K, et al. A prospective study of screen time in adolescence and depression symptoms in young adulthood. Prev Med. 2015;81:108-113. doi:10.1016/j.ypmed.2015.08.009 Nagata JM, Memon Z, Talebloo J, et al. Prevalence and Patterns of Social Media Use in Early Adolescents. Acad Pediatr. 2025;25(4):102784. doi:10.1016/j.acap.2025.102784 Oberle E, Ji XR, Kerai S, Guhn M, Schonert-Reichl KA, Gadermann AM. Screen time and extracurricular activities as risk and protective factors for mental health in adolescence: A population-level study. Prev Med. 2020;141:106291. doi:10.1016/j.ypmed.2020.106291 Pieh C, Humer E, Hoenigl A, et al. Smartphone screen time reduction improves mental health: a randomized controlled trial. BMC Med. 2025;23(1):107. Published 2025 Feb 21. doi:10.1186/s12916-025-03944-z Riehm KE, Feder KA, Tormohlen KN, et al. Associations Between Time Spent Using Social Media and Internalizing and Externalizing Problems Among US Youth. JAMA Psychiatry. 2019;76(12):1266–1273. doi:10.1001/jamapsychiatry.2019.2325 Varona MN, Muela A, Machimbarrena JM. Problematic use or addiction? A scoping review on conceptual and operational definitions of negative social networking sites use in adolescents. Addict Behav. 2022;134:107400. doi:10.1016/j.addbeh.2022.107400 Woolf SH. The Youth Mental Health Crisis in the United States: Epidemiology, Contributors, and Potential Solutions. Pediatrics. 2025;156(5):e2025070849. doi:10.1542/peds.2025-070849 Xiang AH, Martinez MP, Chow T, et al. Depression and Anxiety Among US Children and Young Adults. JAMA Netw Open. 2024;7(10):e2436906. doi:10.1001/jamanetworkopen.2024.36906 BBC: Australia has banned social media for kids under 16. How will it work? https://www.bbc.com/news/articles/cwyp9d3ddqyo Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-470 Overview: Social media use is nearly ubiquitous among adolescents, raising concern about its role in rising rates of depression, anxiety, insomnia, and suicidality. Although prior evidence has been mixed, emerging studies offer new insights on the relationship between social media use and adolescent mental health. Join us as we review current literature and discuss potential strategies to mitigate negative impacts and improve outcomes. Episode resource links: Calvert E, Cipriani M, Dwyer B, et al. Social Media Detox and Youth Mental Health. JAMA Netw Open. 2025;8(11):e2545245. doi:10.1001/jamanetworkopen.2025.45245 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2840489 Clayborne ZM, Capaldi CA, Mehra VM. Associations between digital media use behaviours, screen time and positive mental health in youth: results from the 2019 Canadian Health Survey on Children and Youth. BMC Public Health. 2025;25(1):2303. Published 2025 Jul 3. doi:10.1186/s12889-025-22874-2 Grøntved A, Singhammer J, Froberg K, et al. A prospective study of screen time in adolescence and depression symptoms in young adulthood. Prev Med. 2015;81:108-113. doi:10.1016/j.ypmed.2015.08.009 Nagata JM, Memon Z, Talebloo J, et al. Prevalence and Patterns of Social Media Use in Early Adolescents. Acad Pediatr. 2025;25(4):102784. doi:10.1016/j.acap.2025.102784 Oberle E, Ji XR, Kerai S, Guhn M, Schonert-Reichl KA, Gadermann AM. Screen time and extracurricular activities as risk and protective factors for mental health in adolescence: A population-level study. Prev Med. 2020;141:106291. doi:10.1016/j.ypmed.2020.106291 Pieh C, Humer E, Hoenigl A, et al. Smartphone screen time reduction improves mental health: a randomized controlled trial. BMC Med. 2025;23(1):107. Published 2025 Feb 21. doi:10.1186/s12916-025-03944-z Riehm KE, Feder KA, Tormohlen KN, et al. Associations Between Time Spent Using Social Media and Internalizing and Externalizing Problems Among US Youth. JAMA Psychiatry. 2019;76(12):1266–1273. doi:10.1001/jamapsychiatry.2019.2325 Varona MN, Muela A, Machimbarrena JM. Problematic use or addiction? A scoping review on conceptual and operational definitions of negative social networking sites use in adolescents. Addict Behav. 2022;134:107400. doi:10.1016/j.addbeh.2022.107400 Woolf SH. The Youth Mental Health Crisis in the United States: Epidemiology, Contributors, and Potential Solutions. Pediatrics. 2025;156(5):e2025070849. doi:10.1542/peds.2025-070849 Xiang AH, Martinez MP, Chow T, et al. Depression and Anxiety Among US Children and Young Adults. JAMA Netw Open. 2024;7(10):e2436906. doi:10.1001/jamanetworkopen.2024.36906 BBC: Australia has banned social media for kids under 16. How will it work? https://www.bbc.com/news/articles/cwyp9d3ddqyo Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com The views expressed in this podcast are those of Dr. Domino and his guests and do not necessarily reflect the views of Pri-Med.
Qui dit fin d'année dit Gala des grands crus et des piquettes du Pharmascope! Ne manquez pas cette 9e édition du Gala où nous soulignons le départ d'Isabelle du Pharmascope et l'arrivée d'une nouvelle venue dans l'équipe. ** Veuillez noter que cet épisode ne rencontre pas les critères d'admissibilité pour l'octroi d'unités de formation continue ou de crédits Mainpro+ ** Ressources pertinentes en lien avec l'épisode La catégorie « vitamine D » Lönnroos E, et coll. The Effect of Vitamin D3 Supplementation on the Incidence of Diagnosed Dementia Among Healthy Older Adults-The Finnish Vitamin D Trial. J Gerontol A Biol Sci Med Sci. 2025 Jun 10;80(7):glaf077. La catégorie « Étude simple mais intéressante » Gardner DM, et coll. Patient Self-Guided Interventions to Reduce Sedative Use and Improve Sleep: The YAWNS NB Randomized Clinical Trial. JAMA Psychiatry. 2024 Dec 1;81(12):1187-1197. La catégorie « Mieux-être » Collett G, et coll. Efficacy of Individual-Level Interventions to Mitigate the Risk for Burnout Among Health Care Professionals : A Systematic Review and Meta-analysis of Randomized Controlled Trials. Ann Intern Med. 2025 Nov 18. La catégorie « Techno » Heckman TG, Markowitz JC, Heckman BD. A Generative AI Chatbot for Mental Health Treatment: A Step in the Right Direction? NEJM AI. 2025 Aug 28;2(9). La catégorie « Nostalgie » Díez-Vidal A, Arribas JR. How recent is recent? Retrospective analysis of suspiciously timeless citations. BMJ. 2025 Dec 11;391:e086941. La catégorie « Alimentaire » Wong CX, et coll. Caffeinated Coffee Consumption or Abstinence to Reduce Atrial Fibrillation: The DECAF Randomized Clinical Trial. JAMA. 2025 Nov 9:e2521056.
We return to the podcast circuit in 2026 to examine Scott Galloway: NYU professor, prolific podcaster, and, more recently, part-time life coach for struggling young men.Joining him on an episode of Modern Wisdom with Chris Williamson, we are invited into one of the few remaining forbidden conversational spaces: men, masculinity, and men's problems. You may have been misled by the relentless popularity of Joe Rogan, Modern Wisdom, The Tucker Carlson Show, Triggernometry, The Diary of a CEO, Huberman Lab, and several dozen adjacent properties into thinking these topics are already discussed at length on a near-weekly basis. Alas, this turns out to be a dangerous illusion.In reality, even mentioning men's issues requires an extended ritual acknowledgement of women, failure to perform which risks immediate cancellation. Braving these cultural headwinds, we wade into manly dialogue about masculinity, sex differences, and male malaise. Along the way, we ponder the intricacies of culture war evolutionary psychology, anthropological wars over Man the Hunter, optimised dosages for manly whingeing, and whether making boys learn French verb conjugations qualifies as a human rights abuse.So get your notebooks ready for some important notes from two of the most masculine men in the modern male podcasting space. Men...LinksModern Wisdom: The War On Men Isn't Helping Anyone - Scott GallowayThe Diary of a CEO: Scott Galloway: We're Raising The Most Unhappy Generation In History! Hard Work Doesn't Build WealthAcademic papers ReferencedChanges in gender-based hiring bias (large meta-analysis): Schaerer, M., Du Plessis, C., Nguyen, M. H. B., Van Aert, R. C., Tiokhin, L., Lakens, D., … Gender Audits Forecasting Collaboration. (2023). On the trajectory of discrimination: A meta-analysis and forecasting survey capturing 44 years of field experiments on gender and hiring decisions. Organizational Behavior and Human Decision Processes, 179, 104280.Epidemiology of alcohol use disorder by marital status (US, NESARC-III): Grant, B. F., Goldstein, R. B., Saha, T. D., et al. (2015). Epidemiology of DSM-5 Alcohol Use Disorder: Results from the National Epidemiologic Survey on Alcohol and Related Conditions III. JAMA Psychiatry, 72(8), 757–766.Protective effects of marriage on life expectancy (US Medicare sample): Jia, H., & Lubetkin, E. I. (2020). Life expectancy and active life expectancy by marital status among older US adults: Results from the US Medicare Health Outcome Survey (HOS). SSM – Population Health, 12, 100642.Widowhood and well-being (contrary to claims of increased happiness): Adena, M., Hamermesh, D., Myck, M., & Oczkowska, M. (2023). Home alone: Widows' well-being and time. Journal of Happiness Studies, 24(2), 813–838.Meta-analysis of the widowhood effect on mortality (men and women): Shor, E., Roelfs, D. J., Curreli, M., Clemow, L., Burg, M. M., & Schwartz, J. E. (2012). Widowhood and mortality: A meta-analysis and meta-regression. Demography, 49(2), 575–606.Marriage and life satisfaction across the life course (multi-country): Mikucka, M. (2016). The life satisfaction advantage of being married and gender specialization....
Interview with Amy N. Cohen, PhD, and Matthew Chinman, PhD, authors of Tailored Weight Loss Programs for Adults With Serious Mental Illness: A Randomized Clinical Trial. Hosted by John Torous, MD. Related Content: Tailored Weight Loss Programs for Adults With Serious Mental Illness
Join Drs. Andy Cutler and Roger McIntyre as they discuss the most significant advancements in psychopharmacology over the past year. Their conversation highlights groundbreaking developments and innovations in the field of psychiatry. Roger McIntyre, MD, FRCPC, is a globally recognized psychiatrist and psychopharmacologist who holds pivotal roles in academia, research, and leadership. His research primarily focuses on the phenomenology, neurobiology, and development of novel therapeutics for mood disorders. Dr. McIntyre is currently a Professor of Psychiatry and Pharmacology at the University of Toronto. Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and holds the position of Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York. Resources Thanarajah ES et al. Soft drink consumption and depression mediated by gut microbiome alterations. JAMA Psychiatry 2025;82(11):1095–1102. doi:10.1001/jamapsychiatry.2025.2579 Durgam S et al. Lumateperone as adjunctive therapy in patients with major depressive disorder: results from a randomized, double-blind, phase 3 trial. J Clin Psychiatry 2025;86(4):25m15848. doi: 10.4088/JCP.25m15848 Hendershot CS et al. Once-weekly semaglutide in adults with alcohol use disorder: a randomized clinical trial. JAMA Psychiatry 2025;82(4):395–405. doi: 10.1001/jamapsychiatry.2024.4789 Aron L et al. Lithium deficiency and the onset of Alzheimer's disease. Nature 2025;645:712–21. doi: 10.1038/s41586-025-09335-x Never miss an episode!
In episode 70 we discuss an article about prescription stimulant misuse. Han B, Jones CM, Volkow ND, et al.Prescription Stimulant Use, Misuse, and Use Disorder Among US Adults Aged 18 to 64 Years. JAMA Psychiatry. 2025;82(6):572–581. We also discuss the ASAM toolkit for addressing problems at the pharmacy with buprenorphine, and results of the 2024 NSDUH study. ASAM:Addressing Issues at the Pharmacy with Buprenorphine Prescriptions Link to report pharmacy issues STATNews:Tobacco use, binge drinking decrease as Americans consume more marijuana, survey finds --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go tothis link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visitMI CARES. CME:https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ --- Original theme music:composed and performed by Benjamin Kennedy Audio editing: Michael Bonanno Executive producer:Dr. Patrick Beeman A podcast fromArs Longa Media --- This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice. The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. --- Email: addictionmedicinejournalclub@gmail.com Facebook:@AddictionMedJC Facebook Group:Addiction Medicine Journal Club Instagram:@AddictionMedJC Threads:@AddictionMedJC YouTube:addictionmedicinejournalclub Twitter/X:@AddictionMedJC --- Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. Learn more about your ad choices. Visit megaphone.fm/adchoices
In our final episode of 2025 The Psych Review team are lead by Milla down the twisting rabbit hole that is inflammation in neuropsychiatry. The team discuss recent evidence around proposed inflammatory mechanisms that might underpin the psychiatric conditions we discuss every episode.The references for this episode are:Milla: Upthegrove, Rachel et al. Current Position and Future Direction of Inflammation in Neuropsychiatric Disorders, A Review. JAMA Psychiatry, volume 82, number 10, October 2025.The Psych Review was brought to you by Call to Mind, a telepsychiatry service that you can learn more about at www.calltomind.com.au. The original music in our podcast was provided by the very talented John Badgery, and our logo was designed by the creative genius of Naz.
La dépression légère à modérée ne nécessite pas toujours un traitement médicamenteux. De nombreuses études montrent que certains remèdes naturels, bien choisis, peuvent agir efficacement sur l'humeur, l'énergie et la motivation. Sans remplacer un suivi médical, ces solutions offrent une alternative douce et scientifiquement validée.Le plus célèbre d'entre eux est sans doute le millepertuis (Hypericum perforatum). Cette plante agit sur la sérotonine, la dopamine et la noradrénaline — trois neurotransmetteurs essentiels à la régulation de l'humeur. Plusieurs méta-analyses ont montré que, pour les dépressions légères à modérées, le millepertuis est aussi efficace que certains antidépresseurs chimiques, tout en provoquant moins d'effets secondaires. Mais prudence : il interagit avec de nombreux médicaments (pilule contraceptive, anticoagulants, etc.) et doit être pris sous supervision médicale.Autre allié puissant : l'exercice physique régulier. Selon une étude publiée dans JAMA Psychiatry, 30 minutes d'activité physique cinq fois par semaine réduisent les symptômes dépressifs presque autant qu'un traitement médicamenteux. Le sport stimule la sécrétion d'endorphines, de dopamine et de BDNF, une protéine qui favorise la régénération des neurones. En clair, bouger modifie la chimie du cerveau de manière durable et positive.L'alimentation joue également un rôle clé. Les régimes riches en oméga-3 (présents dans le saumon, les sardines ou les graines de lin) sont associés à un risque plus faible de dépression. Ces acides gras participent au bon fonctionnement des membranes neuronales. De même, une carence en vitamine D, fréquente en hiver, est liée à une baisse de moral. Un apport suffisant — via le soleil, les œufs ou les suppléments — peut aider à rétablir l'équilibre.Parmi les autres pistes validées par la science : la méditation de pleine conscience, qui réduit les rechutes dépressives de près de 40 % selon une étude de l'Université d'Oxford, et la luminothérapie, particulièrement efficace contre la dépression saisonnière. S'exposer chaque matin à une lumière blanche intense pendant 30 minutes régule la mélatonine et stabilise l'humeur.Enfin, le sommeil reste un pilier souvent négligé : se coucher à heures régulières et éviter les écrans le soir améliore la production naturelle de sérotonine.En somme, les antidépresseurs naturels les plus efficaces — sport, lumière, plantes, alimentation, méditation — agissent tous sur un même levier : restaurer l'équilibre biologique du cerveau, sans effets secondaires lourds. Une preuve que la nature et nos habitudes peuvent, parfois, rivaliser avec la chimie. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
In episode 66 we discuss an article about smoking during substance use disorder recovery. Parks MJ, Blanco C, Creamer MR, et al. Cigarette Smoking During Recovery From Substance Use Disorders. JAMA Psychiatry. Published online August 13, 2025. We also discuss how the White House is pressuring the FDA to fast-track nicotine products and shenanigans regarding alcohol in the upcoming FDA dietary guidelines. Reuters: US FDA to fast-track nicotine pouch reviews amid White House pressure Vox: RFK Jr. and the White House buried a major study on alcohol and cancer. Here's what it shows. Draft Report: Scientific Findings of the Alcohol Intake & Health Study for Public Comment --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ --- Original theme music: composed and performed by Benjamin Kennedy Audio editing: Michael Bonanno Executive producer: Dr. Patrick Beeman A podcast from Ars Longa Media --- This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice. The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. --- Email: addictionmedicinejournalclub@gmail.com Facebook: @AddictionMedJC Facebook Group: Addiction Medicine Journal Club Instagram: @AddictionMedJC Threads: @AddictionMedJC YouTube: addictionmedicinejournalclub Twitter/X: @AddictionMedJC --- Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. Learn more about your ad choices. Visit megaphone.fm/adchoices
A new study is making headlines — not because kids are on screens too much, but because many can’t stop. Dr Justin Coulson unpacks fresh research linking addictive screen use (not screen time itself) with anxiety, depression, and suicidal thoughts in teens. Learn what “addiction” really means, why it’s not an official diagnosis, and how to protect your child without constant conflict. KEY POINTS The latest data from the Adolescent Brain Cognitive Development Study shows addictive patterns of screen use — not hours online — are tied to poorer mental health. “Addictive” use means kids feel distress when not online, use screens to regulate emotions, or can’t stop even when it causes problems. There’s no official “screen addiction” diagnosis, but the behaviour patterns are real — and concerning. Justin shares practical strategies using the Three E’s of Effective Discipline to reduce conflict and foster healthy habits. Real-life example: how the Coulson family handled screen boundaries with collaboration, not control. QUOTE OF THE EPISODE “Time on a device isn’t the problem. It’s when kids can’t stop that their mental health starts to suffer.” RESOURCES MENTIONED Adolescent Brain Cognitive Development (ABCD) Study, JAMA Psychiatry, June 2024 Screen "addiction" and mental Health - Technosapiens Tools: Freedom App, Forest App, Brick, Unplug Childhood Framework: The Three E’s of Effective Discipline (Explore, Explain, Empower) ACTION STEPS FOR PARENTS Have a calm conversation about how and why your child uses screens. Model mindful use — show your own limits and honesty about the struggle. Create structure, not punishment — consistent times, agreed limits. Watch for red flags like irritability, secrecy, or big emotions when screens are removed. Offer alternatives — list 10+ enjoyable non-screen activities your child can choose from. See omnystudio.com/listener for privacy information.
Interview with Declan M. McLoughlin, PhD, author of Serial Ketamine Infusions as Adjunctive Therapy to Inpatient Care for Depression: The KARMA-Dep 2 Randomized Clinical Trial. Hosted by John Torous, MD. Related Content: Serial Ketamine Infusions as Adjunctive Therapy to Inpatient Care for Depression
Thank you to everyone who tuned into my live video! Join me for my next live video in the app.Trigger Warnings: Trump Disbands CongressSources:Democracy Now!democracynow.org/2025/10/8/adel…“Scary Precedent”: GOP Blocks Rep.-Elect Adelita Grijalva from Taking Seat Amid Epstein Files FightRepresentative-elect Adelita Grijalva, who won a special election for a House seat in Arizona two weeks ago, has still not been sworn in to Congress. Republican Speaker of the House Mike Johnson is blaming the government shutdown for the delay, even though he previously expedited the swearing-in of multiple Republicans who won their special elections before election results were even in. It's more likely, say supporters, that Grijalva is being held up to prevent what she has pledged will be her first act in Congress: adding her name to and thus triggering a vote on California Congressmember Ro Khanna's bill for the public release of files related to the federal investigation of sex trafficker Jeffrey Epstein. “She needs to get sworn in today,” says Khanna, adding that every day Grijalva is not seated in the House “is breaking precedent and depriving people of who they voted for.” Grijalva says, “This is an incredibly scary precedent to set. If you don't agree with the politics of the speaker, then they can keep you out of your duly elected office.” Khanna and Grijalva also discuss the legacy of Grijalva's late father, the longtime Arizona Congressmember Raúl Grijalva; the Trump administration's crackdown on immigration; right-wing attacks on freedom of the press; and more.AP Newsapnews.com/article/house-…Speaker Johnson keeps the House away as he fights to end the government shutdownHouse members' absence during the government shutdown is creating a political dilemma for Republican Speaker Mike Johnson and is testing his leadership.Chicago Tribunechicagotribune.com/2025/10/10/mik…Speaker Mike Johnson keeps the House away as he fights to end ...Mike Johnson is the speaker of a House that is no longer in session.POLITICOpolitico.com/news/2025/10/0…Mike Johnson sticks to no-show shutdown strategy as ... - Politico“There is absolutely no reason for the House to be out of session,” GOP Rep. Kevin Kiley said. “It's embarrassing.'Democratic Erosion Consortiumdemocratic-erosion.org/2025/04/18/how…How to Erode a Democracy: Hungary's Illiberal Turn Under OrbánThis blog post examines how Viktor Orbán has used media control, legal manipulation, and populist nationalism to methodically destroy Hungary's democratic institutions and turn the nation into the first “illiberal democracy” in the EU.NPRnpr.org/2025/04/20/nx-…Hungary's Orban demonstrates how to dismantle democracy - NPRThe dismantling of Hungary's democracy is a point of fascination for political scientists around the world — including those advising the Trump administration.cnncnn.com/2020/03/30/eur…Hungarian parliament votes to let Viktor Orban rule by decree ... - CNNHungary's parliament has voted to allow Prime Minister Viktor Orban to rule by decree indefinitely, in order to combat the coronavirus pandemic, giving the populist leader extra powers to unilaterally…CNNcnn.com/2025/10/08/pol…Tempers flare between Democratic senators and Speaker Johnson over Grijalva's swearing in and shutdown strategyArizona's Democratic senators got into a hallway confrontation with Republican House Speaker Mike Johnson on Wednesday as the government shutdown's eighth day dragged on.RFKjr & Autism: I Wrote a Foreword Just for YouSourcesCounter/neutral positions from regulators and clinical bodies* European Medicines Agency (EMA), PRAC communications on paracetamol in pregnancy: EMA has stated available evidence does not establish a causal link; use remains appropriate when clinically indicated at the lowest effective dose. Overview page: https://www.ema.europa.eu/en/medicines/human/referrals/paracetamol* (If needed: EMA general paracetamol product information hub where PRAC updates are posted.)* American College of Obstetricians and Gynecologists (ACOG). ACOG Guidance: Acetaminophen use during pregnancy. ACOG states evidence of neurodevelopmental harms is inconsistent and methodologically limited; acetaminophen remains appropriate when indicated. Practice Advisory/FAQ landing: https://www.acog.org/womens-health/faqs/medication-safety-during-pregnancySystematic reviews/meta-analyses with nuanced conclusions* Alemany S et al. Prenatal and postnatal exposure to acetaminophen and ADHD and autism spectrum symptoms in childhood: meta-analysis/pooled observational evidence. European Journal of Epidemiology (2021). Publisher page (Springer): https://link.springer.com/article/10.1007/s10654-021-00757-3U.S. federal perspective* U.S. FDA Drug Safety (Acetaminophen use in pregnancy). FDA has not concluded causality with autism; advises using the lowest effective dose for the shortest duration. Consumer/Drug Safety hub: https://www.fda.gov/consumers/consumer-updates/acetaminophen-overdose-and-liver-injury-know-ingredients-your-medicine* For pregnancy-specific FDA language, see: https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/medication-use-during-pregnancy-and-lactationSupportive association signals (observational; not proof of causality, few supportive links exist)* Ji Y et al. Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder. JAMA Psychiatry (2019). Link: https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2753510Evidence on emotional and social pain blunting* Social pain/evaluative processing: Experimental psychology studies have reported that standard doses of acetaminophen can reduce the distress of social rejection and blunt affective evaluations, suggesting overlap between physical and social pain processing in the brain. These findings support the idea that acetaminophen influences affective components of pain perception, though effect sizes are modest and not uniformly replicated across all paradigms. pbs* Risk of overgeneralization: While these lab findings are provocative, they do not establish acetaminophen as a mood treatment. Regulatory and clinical bodies do not recommend acetaminophen for depression, and evidence for sustained antidepressant benefit is lacking. pbs This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit johnnyprofaneknapp.substack.com/subscribe
Uma notícia que pode mudar a forma como pensamos o tratamento de um dos transtornos mais desafiadores da psiquiatria. A semaglutida, amplamente utilizada no manejo da obesidade, parece ter resultados promissores no tratamento do Transtorno por Uso de Álcool. No episódio 331 do PQU Podcast, fazemos uma revisão crítica de um estudo recente publicado na JAMA Psychiatry sobre o assunto. Apresentamos os dados e trazemos nossa visão crítica sobre o que realmente significam: é evidência com opinião. Convidamos você, psiquiatra em formação, para escutar o episódio completo na sua plataforma preferida. Não perca!
You requested; we delivered. Lots of Science Fictions listeners have asked us to take a look into Donald Trump and RFK, Jr.'s recent claims about Tylenol (that is, paracetamol or acetaminophen—all the same thing). Does it cause autism?It turns out there's more to this than you might've thought—regardless of all the recent hype, a lot of very reputable scientists take the idea seriously. But should they? In this emergency podcast, we go through all the relevant studies.The Science Fictions podcast is brought to you by Works in Progress magazine. In the ad this week we mentioned “The Death Rays that Guard Life”, an article from Issue 20 of the magazine about far-UVC light and how—with a lot more research—it might be the next big thing for reducing the spread of germs in hospitals and classrooms. Find that and many other articles and podcasts at worksinprogress.co.Show notes* The FDA's September 2025 announcement on Tylenol and autism* The UK's Department of Health and Social Care announcement the same day* “The phrase ‘no evidence' is a read flag for bad science communication”, by Scott Alexander* 2003 theoretical paper with speculation about paracetamol and neurodevelopmental disorders* 2013 sibling control study in the International Journal of Epidemiology* “Ecological” study in Environmental Health from 2013 about circumcision rates, paracetamol, and autism* 2015 Danish seven-year follow-up study* 2019 cord blood study in JAMA Psychiatry* 2021 “consensus statement” on paracetamol and neurodevelopment* 2025 Japanese sibling-control study* 2024 very large Swedish sibling-control study* Study that sparked the current debate: the “Navigation Guide” review from Environmental Health* Description of what “Navigation Guide” is* STAT News on the evidence for a paracetamol-autism link; and on the controversy about the Dean of the Harvard School of Public Health* White House statement defending the existence of the link* BMJ article summing up the controversyCreditsThe Science Fictions podcast is produced by Julian Mayers at Yada Yada Productions. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit sciencefictionspod.substack.com/subscribe
REFERENCES 1. Miller RV. Tylenol autism lawsuit. Lawsuit Information Center. September 21, 2025. Accessed September 25, 2025. https://www.lawsuit-information-center.com/tylenol-autism-lawsuit.html 2. Gerstein AS, Niederhelman EF. Harvard's public health dean was paid $150,000 to testify Tylenol causes autism. The Harvard Crimson. September 24, 2025. Accessed September 25, 2025. https://www.thecrimson.com/article/2025/9/24/autism-dean-public-health/ 3. Poll: Most Americans encounter health misinformation, and most aren't sure whether it's true or false. News Release. KFF. August 22, 2023. Accessed September 26, 2025. https://www.kff.org/covid-19/poll-most-americans-encounter-health-misinformation-and-most-arent-sure-whether-its-true-or-false/ 4. Prada D, Ritz B, Bauer AZ, et al. Evaluation of the evidence on acetaminophen use and neurodevelopmental disorders using the Navigation Guide methodology. Environ Health. 2025 Aug 14;24(1):56. doi: 10.1186/s12940-025-01208-0. 5. Ahlqvist VH, Sjöqvist H, Dalman C, et al. Acetaminophen use during pregnancy and children's risk of autism, ADHD, and intellectual disability. JAMA. 2024;331(14):1205–1214. doi:10.1001/jama.2024.3172 6. Alemany S, Avella-García C, Liew Z, et al. Prenatal and postnatal exposure to acetaminophen in relation to autism spectrum and attention-deficit and hyperactivity symptoms in childhood: meta-analysis in six European population-based cohorts. Eur J Epidemiol. 2021 Oct;36(10):993-1004. doi: 10.1007/s10654-021-00754-4. 7. Ji Y, Azuine RE, Zhang Y, et al. Association of cord plasma biomarkers of in utero acetaminophen exposure with risk of attention-deficit/hyperactivity disorder and autism spectrum disorder in childhood. JAMA Psychiatry. 2020;77(2):180–189. doi:10.1001/jamapsychiatry.2019.3259
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-452 Overview: The healthcare landscape is undergoing a sea change, significantly impacting established, evidence-based recommendations. Media coverage suggests that the HHS Secretary plans to release a report linking acetaminophen use during pregnancy with an increased risk of autism spectrum disorder (ASD) in offspring as well as linking maternal folate deficiency with ASD—associations that have not been supported by evidence. If promoted by public health agencies, such discrepancies pose a dilemma for clinicians who have relied on and trusted that guidance reflects evidence and is grounded in scientific methods. Join us to review the evidence on acetaminophen and ASD risk and learn strategies to ensure your practice is based on valid findings. Episode resource links: Ahlqvist VH, Sjöqvist H, Dalman C, et al. Acetaminophen Use During Pregnancy and Children's Risk of Autism, ADHD, and Intellectual Disability. JAMA. 2024;331(14):1205–1214. doi:10.1001/jama.2024.3172 Damkier, P., Gram, E. B., Ceulemans, M., Panchaud, A., Cleary, B., Chambers, C., Weber-Schoendorfer, C., Kennedy, D., Hodson, K., Grant, K. S., Diav-Citrin, O., Običan, S. G., Shechtman, S., & Alwan, S. (2025). Acetaminophen in Pregnancy and Attention-Deficit and Hyperactivity Disorder and Autism Spectrum Disorder. Obstetrics and gynecology, 145(2), 168–176. https://doi.org/10.1097/AOG.0000000000005802 Ji Y, Azuine RE, Zhang Y, et al. Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood. JAMA Psychiatry. 2020;77(2):180–189. doi:10.1001/jamapsychiatry.2019.3259 Hirota T, King BH. Autism Spectrum Disorder: A Review. JAMA. 2023;329(2):157–168. doi:10.1001/jama.2022.23661 Liu, X., Zou, M., Sun, C., Wu, L., & Chen, W. X. (2022). Prenatal Folic Acid Supplements and Offspring's Autism Spectrum Disorder: A Meta-analysis and Meta-regression. Journal of autism and developmental disorders, 52(2), 522–539. https://doi.org/10.1007/s10803-021-04951-8 DSM-5-TR: Neurocognitive Disorders Supplement; October 2022. https://psychiatryonline.org/pb-assets/dsm/update/DSM-5-TR_Neurocognitive-Disorders-Supplement_2022_APA_Publishing.pdf https://www.npr.org/sections/shots-health-news/2025/09/06/nx-s1-5532143/hhs-responds-to-report-about-autism-and-acetaminophen Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-452 Overview: The healthcare landscape is evolving rapidly, and clinicians are navigating conflicting guidance on established, evidence-based recommendations. Recent news suggest acetaminophen use during pregnancy causes autism spectrum disorder (ASD), which is not the consensus of medical experts based on available data. When guidance from various sources conflicts with established research, clinicians face challenges in providing evidence-based care. Join us to review the current evidence on acetaminophen and ASD risk. Episode resource links: Ahlqvist VH, Sjöqvist H, Dalman C, et al. Acetaminophen Use During Pregnancy and Children's Risk of Autism, ADHD, and Intellectual Disability. JAMA. 2024;331(14):1205–1214. doi:10.1001/jama.2024.3172 Damkier, P., Gram, E. B., Ceulemans, M., Panchaud, A., Cleary, B., Chambers, C., Weber-Schoendorfer, C., Kennedy, D., Hodson, K., Grant, K. S., Diav-Citrin, O., Običan, S. G., Shechtman, S., & Alwan, S. (2025). Acetaminophen in Pregnancy and Attention-Deficit and Hyperactivity Disorder and Autism Spectrum Disorder. Obstetrics and gynecology, 145(2), 168–176. https://doi.org/10.1097/AOG.0000000000005802 Ji Y, Azuine RE, Zhang Y, et al. Association of Cord Plasma Biomarkers of In Utero Acetaminophen Exposure With Risk of Attention-Deficit/Hyperactivity Disorder and Autism Spectrum Disorder in Childhood. JAMA Psychiatry. 2020;77(2):180–189. doi:10.1001/jamapsychiatry.2019.3259 Hirota T, King BH. Autism Spectrum Disorder: A Review. JAMA. 2023;329(2):157–168. doi:10.1001/jama.2022.23661 Liu, X., Zou, M., Sun, C., Wu, L., & Chen, W. X. (2022). Prenatal Folic Acid Supplements and Offspring's Autism Spectrum Disorder: A Meta-analysis and Meta-regression. Journal of autism and developmental disorders, 52(2), 522–539. https://doi.org/10.1007/s10803-021-04951-8 DSM-5-TR: Neurocognitive Disorders Supplement; October 2022. https://psychiatryonline.org/pb-assets/dsm/update/DSM-5-TR_Neurocognitive-Disorders-Supplement_2022_APA_Publishing.pdf https://www.npr.org/sections/shots-health-news/2025/09/06/nx-s1-5532143/hhs-responds-to-report-about-autism-and-acetaminophen Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com
Send us a message with this link, we would love to hear from you. Standard message rates may apply.Screen time impacts our mental health in significant ways, with research suggesting particular risks for teens who spend more than three hours daily on social media.• Higher social media usage linked to increased rates of depression, anxiety, and stress• Teens more vulnerable to negative mental health effects than adults• Using social media to escape negative feelings raises mental health risks• Limiting social media to 30 minutes per day can lower depression and anxiety• Open conversations about online experiences help teens develop healthy digital habits• Unrealistic images and constant comparisons on social media harm self-worth• Adults experience similar but less pronounced negative effects from excessive screen time• Maintaining real-life relationships outside digital spaces provides important balance• Screen time isn't benign—moderation is key to protecting mental wellbeingCheck us out on Instagram, find us on Threads, or send us an email at yourcheckuppod@gmail.com.References1. Associations Between Time Spent Using Social Media and Internalizing and Externalizing Problems Among US Youth. Riehm KE, Feder KA, Tormohlen KN, et al. JAMA Psychiatry. 2019;76(12):1266-1273. doi:10.1001/jamapsychiatry.2019.2325.2. Impact of Social Media Use on Mental Health Within Adolescent and Student Populations During COVID-19 Pandemic: Review. Draženović M, Vukušić Rukavina T, Machala Poplašen L. International Journal of Environmental Research and Public Health. 2023;20(4):3392. doi:10.3390/ijerph20043392.3. Annual Research Review: Adolescent Mental Health in the Digital Age: Facts, Fears, and Future Directions. Odgers CL, Jensen MR. Journal of Child Psychology and Psychiatry, and Allied Disciplines. 2020;61(3):336-348. doi:10.1111/jcpp.13190.4. Addictive Screen Use Trajectories and Suicidal Behaviors, Suicidal Ideation, and Mental Health in US Youths. Xiao Y, Meng Y, Brown TT, Keyes KM, Mann JJ. JAMA. 2025;:2835481. doi:10.1001/jama.2025.7829.5. Exploring the Relationship Between Social Media Use and Symptoms of Depression and Anxiety Among Children and Adolescents: A Systematic Narrative Review. Saleem N, Young P, Yousuf S. Cyberpsychology, Behavior and Social Networking. 2024;27(11):771-797. doi:10.1089/cyber.2023.0456.6. Adolescents' Interactive Electronic Device Use, Sleep and Mental Health: A Systematic Review of Prospective Studies. Dibben GO, Martin A, Shore CB, et al. Journal of Sleep Research. 2023;32(5):e13899. doi:10.1111/jsr.13899.7. Relationship Between Depression and the Use of Mobile Technologies and Social Media Among Adolescents: Umbrella Review. Arias-de la Torre J, Puigdomenech E, García X, et al. Journal of Medical Internet Research. 2020;22(8):e16388. doi:10.2196/16388.Support the showSubscribe to Our Newsletter! Production and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski
Interview with Sharmili Edwin Thanarajah, MD, author of Soft Drink Consumption and Depression Mediated by Gut Microbiome Alterations. Hosted by John Torous, MD. Related Content: Soft Drink Consumption and Depression Mediated by Gut Microbiome Alterations GLP-1 Receptor Agonists for Pharmacologically Induced Weight Gain
Most people retire with a solid income plan but no plan for a life they actually want to live. In this episode, I discuss the five human pillars that make retirement feel meaningful, not just financially viable: Purpose, Identity, Relationships, Structure, and Well-being. Expect punchy stories, research-backed insights, and practical prompts to start building a life worth funding. What you'll learn Why money ≠ meaning in retirement, and how outcomes beat incomes. The Five Pillars framework (Purpose, Identity, Relationships, Structure, Well-being) and how each one stabilises your next chapter. The hidden risk of identity loss after the job title disappears, and two better questions to ask yourself now. Why too much unstructured time can feel like freedom that turns to fog, and simple ways to add rhythm without losing flexibility. The science bits (in plain English): Only 27% of retirees report feeling very fulfilled day-to-day (Stanford Center on Longevity). A strong sense of purpose links to a 15% lower risk of death (JAMA Psychiatry). The Harvard Adult Development Study shows close relationships are the biggest predictor of long-term happiness. 1 in 4 experience mild to moderate depression post-retirement—often due to lost meaning, routine, and social contact (NHS). Challenge of the Week Score yourself 1–10 on each pillar: Purpose, Identity, Relationships, Structure, Well-being. Pick the lowest score and do one tiny action this week to move it up by one point (e.g., book coffee with a friend, start a 15-minute morning walk, schedule a creative hour, message someone to mentor). Small moves → big momentum. Resources & links Mentioned research (as cited in the episode): Stanford Center on Longevity — fulfilment in retirement JAMA Psychiatry (2020) — purpose & mortality risk Harvard Study of Adult Development — relationships & happiness NHS guidance/statistics — mental health in later life Want more? Connect with me on LinkedIn and share your Challenge of the Week answers. Buy my book The Retirement You Didn't See Coming Book a time for us to chat about your retirement plans Next episode “The Skill No One Taught You: Spending Money.” We'll get into guilt, scarcity, freedom, joy, and why many retirees have more than enough yet still struggle to spend with confidence.
Quick summaries of articles 51-60. Enjoy! 51. Fun Activities and Recovery Acuff, S. F., et al. A brief measure of non-drug reinforcement: Association with treatment outcomes during initial substance use recovery. Drug and Alcohol Dependence, 256, 111092. 52. Buprenorphine-precipitated Fentanyl Withdrawal Thakrar AP, et al. Buprenorphine-Precipitated Withdrawal Among Hospitalized Patients Using Fentanyl. JAMA Netw Open. 2024 Sep 3;7(9):e2435895. 53. Methadone Vs. Buprenorphine Nosyk B, Et al. Buprenorphine/Naloxone vs Methadone for the Treatment of Opioid Use Disorder. JAMA. 2024 Oct 17. 54. High Daily Doses of Buprenorphine Axeen S, et al. Association of Daily Doses of Buprenorphine With Urgent Health Care Utilization. JAMA Netw Open. 2024 Sep 3;7(9):e2435478. 55. How Buprenorphine Works in Pregnancy Caritis, Steve N. MD; et al. A Pharmacologic Evaluation of Buprenorphine in Pregnancy and the Postpartum Period. Journal of Addiction Medicine ():10.1097/ADM.0000000000001380, September 2, 2024. 56. How Many Quite Attempts Does It Take? Fontes RM, et al. Beyond the first try: How many quit attempts are necessary to achieve substance use cessation? Drug Alcohol Depend. 2024 Dec 8;267:112525. 57. What is Recovery? Zemore SE, et al. Understanding the Shared Meaning of Recovery From Substance Use Disorders: New Findings From the What is Recovery? Study. Subst Abuse. 2023 Sep 15;17:11782218231199372. 58. Semaglutide for Alcohol Use Disorder (The RCT) Hendershot CS, et al. Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2025 Feb 12:e244789. 59. Low-Dose Buprenorphine Initiation (Micro-induction) Suen LW, et al. Outpatient Low-Dose Initiation of Buprenorphine for People Using Fentanyl. JAMA Netw Open. 2025 Jan 2;8(1):e2456253. 60. Lisdexamfetamine for methamphetamine use disorder Ezard N, et al LiMA Investigator Group. Lisdexamfetamine in the treatment of methamphetamine dependence: A randomised, placebo-controlled trial. Addiction. 2024 Dec 19. --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ --- Original theme music: composed and performed by Benjamin Kennedy Audio editing: Michael Bonanno Executive producer: Dr. Patrick Beeman A podcast from Ars Longa Media --- This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice. The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. --- Email: addictionmedicinejournalclub@gmail.com Facebook: @AddictionMedJC Facebook Group: Addiction Medicine Journal Club Instagram: @AddictionMedJC Threads: @AddictionMedJC YouTube: addictionmedicinejournalclub Twitter/X: @AddictionMedJC --- Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. Learn more about your ad choices. Visit megaphone.fm/adchoices
Interview with Anna D. Ratzliff, MD, PhD and Andrew J. Saxon, MD authors of Collaborative Care for Opioid Use Disorder in Primary Care: A Hybrid Type 2 Cluster Randomized Trial. Hosted by John Torous, MD. Related Content: Collaborative Care for Opioid Use Disorder in Primary Care
ຢາຕ້ານອາການຊຶມເສົ້າ ເປັນຢາທີ່ໃຊ້ກັນຢ່າງກ້ວາງຂວາງທົ່ວໂລກ ແລະໃນອອສເຕຣເລັຍ. ປະມານຫນຶ່ງໃນເຈັດຄົນ ຂອງຊາວອອສເຕຣເລັຍ ກໍາລັງໃຊ້ຢາຕ້ານອາການຊຶມເສົ້າ (3.9ລ້ານຄົນ). ການທົບທວນ ທີ່ຖືກພິມໃນວາຣະສານ JAMA Psychiatry ຮວມການສຶກສາ 38 ເລື້ອງ ທີ່ມີໄລຍະສັງເກດຫລາຍກວ່າສອງອາທິດ, ຊຶ່ງເປັນໄລຍະເວລາທີ່ສໍາຄັນ ຊຶ່ງຄາດວ່າ ອາການຖອນຢາຈະເກີດຂືຶ້ນ.
Concerned about screen time—both your kids' and your own? Perhaps you're navigating the decision of when to give your child a phone, or maybe you're rethinking past choices. While we all strive for improvement in managing screen time, our aim isn't to condemn technology or advocate for device-free living.Today, we welcome Dr. Ryan Sultan, an internationally recognized, double board-certified psychiatrist who directs the Sultan Mental Health Informatics and Adaptation Lab at Columbia University. Dr. Sultan offers expert guidance on discussing algorithms and short-form content with your children, fostering independent thinking. We'll also delve into the spread of misinformation and reactionary content, as well as the correlation between screen time and depression. Tune in for his practical advice on immediate steps you can take to help your kids gain better control over their screen time, even if they're already knee deep.(00:00:58) Welcome Dr. Ryan Sultan to the podcast.(00:04:25) If you only get one thing out of this conversation, THIS is it.(00:09:28) What is actually happening in the brain when we're using our phones? (00:15:27) Talking to our kids about algorithms.(00:21:20) When to introduce screens to kids and what age to give a phone.(00:26:16) Neurodivergence and devices: a higher risk group.(00:30:12) Heavy social media use and depression, anxiety,and suicidal ideation.(00:33:31) Multiplayer video games: are they social media?(00:36:10) Setting boundaries: a medium between doing nothing and taking it all away.(00:43:28) Sultan Lab Big Data for social media and mental health guidelines.(00:48:18) Parents, we need regulation and it's NOT impossible.(00:53:42) Summary and what to implement in your household right now to get better control over screen time.(00:56:00) Where to find Dr. Ryan Sultan. Integrative Psychiatry is a psychiatry practice that takes a holistic, collaborative approach to mental health care. The Columbia-trained clinical team provides expert, evidence-based treatment for ADHD, anxiety, depression, substance use, eating disorders, and other mental health conditions. The clinicians combine psychotherapy, research-supported psychotropic medications, and expertise as adult, adolescent, and child psychiatrists to deliver patient-centered care that meets each individual's unique needs—supporting long-term mental well-being and overall wellness.The practice is led by Dr. Ryan Sultan, an internationally recognized, double board-certified psychiatrist. He also serves as an Assistant Professor of Clinical Psychiatry at Columbia University, where he leads the Sultan Mental Health Informatics and Adaptation Lab.To learn more, visit Integrative Psychiatry or Sultan Lab. References:Sultan, R. S. (2017). Off-Label Prescribing of Antipsychotics for Youths: Who Should Be Treated? Psychiatric Times, 34(9), 26.Sultan, R. S., Liu, S. M., Hacker, K. A., & Olfson, M. (2021). Adolescents with Attention-Deficit/Hyperactivity Disorder: Adverse Behaviors and Comorbidity. Journal of Adolescent Health, 68(2), 284-291.Sultan, R. S., Saunders, D. C., & Veenstra-VanderWeele, J. (2025). Protective Effects of ADHD Medication on Real-World Outcomes. JAMA Psychiatry.Want to leave the TTSL Podcast a voicemail? We love your questions and adore hearing from you. https://www.speakpipe.com/TheThickThighsSaveLivesPodcastThe CVG Nation app, for iPhoneThe CVG Nation app, for AndroidOur Fitness FB Group.Thick Thighs Save Lives Workout ProgramsConstantly Varied Gear's Workout Leggings
Female Pelvic Pain and Its Relationship to Emotions & Trauma Dr. Adriana Martí When sex hurts, experts still have tons of unanswered questions. Since we don't have much accurate data on the various conditions that make intercourse painful, women often suffer in silence. To help sort this out, Dr. Diana Wiley, a sex therapist, and Dr. Adriana Martí, a pain psychologist, had an informative conversation. Dr. Martí uses the biopsychosocial model, which has emerged as the most comprehensive framework for understanding pain. Coming from a family of physicians, Dr. Marti understood the value of treating the physical body, but she also saw where the biomedical model falls short. That insight led her to embrace integrative, mind-body approaches to care especially for those living with chronic illness or pain. The level of a patient's anger has been shown to be an important predictor of chronic pain symptoms, and cultivating compassion has been shown to positively influence how we process emotions, thus reducing the tendency toward negativity, including anger. Psychological or emotional factors are often involved. Stress, anxiety, depression, guilt, a history of sexual abuse, an upsetting pelvic exam in the past, or relationship troubles can also be at the root of sexual pain. Some women experience vaginismus—an involuntary clenching of vaginal muscles that prevents penetration. Vaginismus is especially common among women who associate their vaginal area with fear or physical trauma. Both the sex therapist and the health psychologist want to include the patient's partner at some point in the therapeutic process. For many couples who have been dealing with a confusing, undefined issue, there is a buildup of resentment and anger. Men often fear hurting their partner. Pleasure can become pain. It is so easy for couples to blame each other and lose sight of the fact that the real problem is a physiological condition, not their partner. Dr. Martí also notes the cultural piece: the expectations related to the family. How does the family relate to pain? In one case, the mother and the grandmother both had pelvic pain. Sometimes the woman gets sucked into the “sick role,” which has the benefit of lowered expectations from the patient, but is ultimately not emotionally healthy. Can pain be unlearned? A study led by Yoni Ashar, PhD, which was published in JAMA Psychiatry, was the first clinical trial of pain reprocessing therapy (PRT). PRT was developed by psychotherapist Alan Gordon to treat primary chronic back pain. Complete details can be found in his book, The Way Out: A Revolutionary, Scientifically Proven Approach to Healing Chronic Pain. There are additional fixes, such as vaginal estrogen or other medicines or creams. Also, pelvic floor therapy (provided by a specially trained physical therapist) can help control vaginal muscles. “Down training” uses a combination of mindfulness, diaphragmatic breathing, meditation, stretching, and visualization to help calm the nervous system. The couple in therapy may be asked to do “outercourse” homework (non-penetrative sex). Some couples put too much focus on penetrative sex and neglect other fun, equally pleasurable sexual activities. Outercourse is a great option because it helps women forget there's a goal, so they can just enjoy the feelings and sensations of the ride! It gets both people out of their brains and into their bodies. Dr. Martí has a private practice where she works with individuals and couples in both English and Spanish. All sessions are done via telehealth. A fifteen-minute phone consultation is the no-charge first step! www.martipsychologicalservices.com
What does it mean to be free? It's a question that's puzzled philosophers for millennia. But what does it mean to be metabolically free? If you've ever felt hangry, crashed after a meal, or dealt with type 2 diabetes, you've experienced the opposite — metabolic imprisonment.My guest today, Ben Azadi, knows this firsthand. In 2008, Ben was obese and unhealthy, struggling to find answers. After shedding 80 pounds and turning his health around, he dedicated his life to helping others do the same. Today, he's a functional health expert, bestselling author, and the founder of Keto Kamp, a global brand empowering people to use ancient healing tools like fasting and the ketogenic lifestyle. His new book, Metabolic Freedom: A 30-Day Guide to Restore Your Metabolism, Heal Hormones & Burn Fat, lays out the blueprint to reclaim your health.In this episode, we dive into:What metabolism really is — and why “slow” or “fast” metabolism may be a mythA groundbreaking study that disproves the idea that metabolism slows with ageWhy fasting insulin is a better marker of health than weight or glucose aloneThe surprising power of “Vitamin G” — gratitude — on your metabolic functionBen's top daily habits and biohacks to supercharge your metabolismBen's approach is all about education over medication — empowering you to take control, rather than outsourcing your health. Ben has also made a personal impact on a member of my family.Links:
Interview with Sameer Jauhar, PhD, author of Incidence and Nature of Antidepressant Discontinuation Symptoms: A Systematic Review and Meta-Analysis. Hosted by John Torous, MD. Related Content: Incidence and Nature of Antidepressant Discontinuation Symptoms
Interview with Aaron Alexander-Bloch, MD, PhD, and Kevin Y. Sun, BA, authors of Polygenic Risk, Psychopathology, and Personalized Functional Brain Network Topography in Adolescence. Hosted by John Torous, MD. Related Content: Polygenic Risk, Psychopathology, and Personalized Functional Brain Network Topography in Adolescence
Without this one thing, every single thing you know and love would disappear. Soil would fail, forests would starve, antibiotics would, well, vanish, and your morning coffee, bread, beer, and even chocolate would be gone. The thing I'm talking about is everywhere. It's probably in your lunch. It's almost certainly in your lungs. It's in your sourdough starter, your compost heap. Got a clue yet? Most people don't actually know what these things are. I'm talking about fungi. Fungi are not plants, not animals, not bacteria — they're something else entirely. And they're really, really old.They're older than dinosaurs, older than sharks — they might even be older than plants, depending on how you define a plant.Today, I'm diving into something I'm actually violently allergic to: fungus. I'm covering everything from what fungi actually are (because it turns out most of us have no idea) to why they might be the most important thing on Earth… ish.In this episode I share: What prokaryotes and eukaryotes areWhat fungi actually areThe different types of fungiHow fungi moved from ocean to land and began a symbiotic relationship with plantsHow fungi can decompose almost anything — including radiationZombie fungus (and whether we should worry)How fungi reproduceWhy they're incredibly usefulSome of the annoying and dangerous things they doHow we might use fungi to help fix the planet.Key quotes:"Fungi are more closely related to us than to plants.""Turns out plants talk way more than you think they do."Sources: Billion-year-old fungal fossils (Nature 2019): https://www.nature.com/articles/s41586-019-1217-0Armillaria “humongous fungus” 9 km² individual: https://www.scientificamerican.com/article/strange-but-true-largest-organism-is-fungus/Prototaxites 8 m Silurian-Devonian giant: https://www.science.org/content/article/ancient-giant-fossils-may-be-world-s-oldest-known-terrestrial-fungi90 % of plants with mycorrhizae (Nature Scitable): https://www.nature.com/scitable/knowledge/library/an-ecological-and-evolutionary-perspective-on-mycorrhizal-24286790/Mycorrhizal carbon sink 3–7 Gt CO₂ yr⁻¹ (Science 2022): https://www.science.org/doi/10.1126/science.abf3457Penicillin discovery background (Nobel Prize): https://www.nobelprize.org/prizes/medicine/1945/fleming/facts/Statins from Penicillium citrinum (review): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958453/Cyclosporine discovery story: https://pubmed.ncbi.nlm.nih.gov/7568434/Psilocybin phase-II depression trial (JAMA Psychiatry 2021): https://jamanetwork.com/journals/jamapsychiatry/fullarticle/2787297Plastic-eating fungus Pestalotiopsis microspora (2011 study): https://pubmed.ncbi.nlm.nih.gov/22269855/ CDC overview of Candida auris drug resistance: https://www.cdc.gov/fungal/candida-auris/Chytrid fungus amphibian decline paper (Science 2006): https://www.science.org/doi/10.1126/science.1125069Mycoremediation and mycofiltration review (Biodegradation 2018): https://link.springer.com/article/10.1007/s10532-018-0914-8Find our full podcast via the website here: https://www.nowthatswhaticall.com/Instagram: https://www.instagram.com/nowthatswhaticallgreen/You can follow me on socials on the below accounts.Instagram: https://www.instagram.com/briannemwest/TikTok: https://www.tiktok.com/@briannemwestLinkedIn: https://www.linkedin.com/in/briannemwest/
Contributor: Jorge Chalit-Hernandez, OMS3 Educational Pearls: Psychedelics are being studied for their therapeutic effects in mental illnesses, including major depressive disorder, post-traumatic stress disorder, anxiety, and many others Classic psychedelics include compounds like psilocybin, LSD, and ayahuasca MDMA and ketamine are often included in psychedelic research, but have a different mechanism of action than the others Their mechanism of action involves agonism of the 5HT2A receptor, among others Given their resurgence, there is an increase in recreational use of these substances A recent study assessed the risks of recreational users developing subsequent psychotic disorders Individuals who visited the ED for hallucinogen use had a greater risk of being diagnosed with a schizophrenia spectrum disorder in the following 3 years Hazard ratio (HR) of 21.32 After adjustment for comorbid substance use and other mental illness, the hazard ratio was 3.53 - still a significant increase compared with the general population They also found an elevated risk for psychedelics when compared to alcohol (HR 4.66) and cannabis (HR 1.47) The study did not assess whether patients received antipsychotics or other treatments in the ED References Lieberman JA. Back to the Future - The Therapeutic Potential of Psychedelic Drugs. N Engl J Med. 2021;384(15):1460-1461. doi:10.1056/NEJMe2102835 Livne O, Shmulewitz D, Walsh C, Hasin DS. Adolescent and adult time trends in US hallucinogen use, 2002-19: any use, and use of ecstasy, LSD and PCP. Addiction. 2022;117(12):3099-3109. doi:10.1111/add.15987 Myran DT, Pugliese M, Xiao J, et al. Emergency Department Visits Involving Hallucinogen Use and Risk of Schizophrenia Spectrum Disorder. JAMA Psychiatry. 2025;82(2):142-150. doi:10.1001/jamapsychiatry.2024.3532 Summarized & Edited by Jorge Chalit, OMS3 Donate: https://emergencymedicalminute.org/donate/
Interview with Pim Cuijpers, PhD, author of Cognitive Behavior Therapy for Mental Disorders in Adults: A Unified Series of Meta-Analyses. Hosted by John Torous, MD Related Content: Cognitive Behavior Therapy for Mental Disorders in Adults
In episode 58 we discuss a randomized controlled trial of semaglutide for alcohol use disorder. Hendershot CS, Bremmer MP, Paladino MB, Kostantinis G, Gilmore TA, Sullivan NR, Tow AC, Dermody SS, Prince MA, Jordan R, McKee SA, Fletcher PJ, Claus ED, Klein KR. Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2025 Feb 12:e244789. We also discuss benzodiazepine tapering guidelines and new ways to use Sublocade. ASAM Clinical Practice Guideline on Benzodiazepine Tapering Sublocade label changes --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ --- Original theme music: composed and performed by Benjamin Kennedy Audio editing: Michael Bonanno Executive producer: Dr. Patrick Beeman A podcast from Ars Longa Media --- This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice. The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. Email: addictionmedicinejournalclub@gmail.com Facebook: @AddictionMedJC Facebook Group: Addiction Medicine Journal Club Instagram: @AddictionMedJC Threads: @AddictionMedJC YouTube: addictionmedicinejournalclub Twitter/X: @AddictionMedJC Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. Learn more about your ad choices. Visit megaphone.fm/adchoices
Interview with Professor Jurgen Unutzer, MD, author of Effective Components of Collaborative Care for Depression in Primary Care: An Individual Participant Data Meta-Analysis. Hosted by John Torous, MD. Related Content: Effective Components of Collaborative Care for Depression in Primary Care
In this episode Dr's J and Santhosh do a deep dive and chew the fat on the facts about ozempic, wegovy and the current crop of weight loss drugs. Along the way they cover gila monsters, synthetic insulins, lizard venom salesmen, ozempic and wegovy differences, cardioprotective and neuroprotective effects, ozempic pregnancies, addiction and reward treatment, kidney protection, prevention of brain shrinkage, alzheimers delay ozempic face and more! So sit back and relax as we cover the many faces of ozempic!Further ReadingJournal reference: JAMA Psychiatry DOI: 10.1001/jamapsychiatry.2024.4789https://www.nejm.org/doi/10.1056/NEJMoa2208601https://www.imperial.ac.uk/news/255214/weight-loss-drug-slow-alzheimers-decline/https://pubmed.ncbi.nlm.nih.gov/35180937/https://www.nature.com/articles/d41586-024-01564-whttps://www.nejm.org/doi/full/10.1056/NEJMoa2307563Support Us spiritually, emotionally or financially here! or on ACAST+travelmedicinepodcast.comBlueSky/Mastodon/X: @doctorjcomedy @toshyfroTikotok: DrjtoksmedicineGmail: travelmedicinepodcast@gmail.comSpotify: https://open.spotify.com/show/28uQe3cYGrTLhP6X0zyEhTPatreon: https://www.patreon.com/travelmedicinepodcast Supporting us monthly has all sorts of perks! You get ad free episodes, bonus musical parody, behind the scenes conversations not available to regular folks and more!! Your support helps us to pay for more guest interviews, better equipment, and behind the scenes people who know what they are doing! https://plus.acast.com/s/travelmedicinepodcast. Hosted on Acast. See acast.com/privacy for more information.
In a recent study published in JAMA Psychiatry, researchers reported that a machine learning model was able to stratify risk for subsequent diagnosis of schizophrenia or bipolar disorder among individuals already receiving psychiatric treatment. Coauthor Søren Dinesen Østergaard, PhD, of Aarhus University in Denmark joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss. Related Content: Machine Learning Model Shows Promise in Early Detection of Serious Mental Illness Predicting Diagnostic Progression to Schizophrenia or Bipolar Disorder via Machine Learning
Professor David Taylor is Director of Pharmacy and Pathology at the Maudsley Hospital and Professor of Psychopharmacology at KCL. David is the Editor-in-Chief of the journal Therapeutic Advances in Psychopharmacology. Professor Taylor has been the lead author of the Maudsley Prescribing Guidelines since their inception in 1993. David has also authored over 375 clinical papers in journals such as the Lancet, BMJ, JAMA Psychiatry, British Journal of Psychiatry and Journal of Clinical Psychiatry. Today we discuss: - What the science says about the effectiveness of anti-depressants.- Evidence based principles for prescribing anti-depressants safely. - Common side effects and withdrawal symptoms. - Do anti-depressants work via so called "emotional numbing" effects?- The use of anti-depressants for other conditions such as OCD and PTSD. - Emerging treatments for depression such as ketamine and psilocybin. - New treatments for psychosis such as KarXT (Cobenfy). Interviewed by Dr. Alex Curmi. Dr. Alex is a consultant psychiatrist and a UKCP registered psychotherapist in-training.If you would like to invite Alex to speak at your organisation please email alexcurmitherapy@gmail.com with "Speaking Enquiry" in the subject line.Alex is not currently taking on new psychotherapy clients, if you are interested in working with Alex for focused behaviour change coaching , you can email - alexcurmitherapy@gmail.com with "Coaching" in the subject line.Give feedback here - thinkingmindpodcast@gmail.com - Follow us here: Twitter @thinkingmindpod Instagram @thinkingmindpodcast Tiktok - @thinking.mind.podcast
Interview with Srividya N. Iyer, PhD, author of An Approach to Providing Timely Mental Health Services to Diverse Youth Populations. Hosted by John Torous, MD. Related Content: An Approach to Providing Timely Mental Health Services to Diverse Youth Populations
Lifting the Cloud: Transcranial Magnetic Stimulation and the Treatment of Major DepressionThis episode provides an in-depth exploration of Transcranial Magnetic Stimulation (TMS) and its impact on psychiatric disorders. TMS has demonstrated effectiveness in numerous clinical trials and serves as a valuable adjunct to traditional therapy. Designed for clinicians and mental health professionals and those they serve, this podcast offers insights into:Identifying appropriate patient populations for TMS therapy. Understanding the TMS treatment process from start to finish. Exploring the role of neuromodulation in reshaping brain function for long-term improvement. Reviewing clinical outcome data supporting TMS in the treatment of major depressive disorder. Gain a deeper understanding of how TMS and neuromodulation techniques are advancing the field of functional neuropsychiatry and providing new hope for patients. Objectives: Identify appropriate patient populations for Transcranial Magnetic Stimulation (TMS) treatment of psychiatric disorders.Describe the treatment process of Transcranial Magnetic Stimulation. Describe possible adverse events associated with Transcranial Magnetic Stimulation.Explain how neuromodulation techniques impact long-term changes in brain network functioning.Discuss clinical outcome data for Transcranial Magnetic Stimulation treatment. Guests: Dr. Henry Emerle, MDDr. Rich Whitaker, PhDBios: Dr. Rich Whitaker began his career in the Quad Cities in 1994 as a doctoral intern at the historic Marriage and Family Counseling Service in Rock Island, Illinois as part of his Ph.D. in Marriage and Family Therapy from Brigham Young University. Since that pivotal year, Dr. Whitaker has pursued a career in community mental health, providing services, supervision, and executive administration at community mental health centers in Grand Island, Nebraska (9 years as COO) and Jasper, Indiana (12 years as CFO). Since January 2017, Rich has served as the CEO of Vera French Community Mental Health Center in Davenport, Iowa. In addition to serving as a Director of Region 7 on the Board of the National Council for Mental Wellbeing, Dr. Whitaker also serves as a Government Relations Committee member for the Iowa Association of Community Providers, as a Board member of Churches United in the Quad Cities, and as a member of the Eastern Iowa MHDS Regional Advisory Committee.Rich and Miriam are the parents of 3 daughters and one son and the proud grandparents of a growing number of highly intelligent and multi-talented grandchildren. In his spare time, Rich enjoys family time, all types of sports and exercise, singing with the Quad City Singers, and service in the church and community.Henry Emerle, MD completed his medical school training at the University of Illinois College of Medicine at Urbana-Champaign, IL. He completed Psychiatry Residency training as well as Geriatric Psychiatry Fellowship training at the University of Michigan in Ann Arbor, MI. He is the Medical Director at Vera French Community Mental Health Center. He enjoys spending time with his family exploring the many charming towns in Iowa along the Mississippi River. References: Cash RFH, Cocchi L, Lv J, Fitzgerald PB, Zalesky A. Functional Magnetic Resonance Imaging–Guided Personalization of Transcranial Magnetic Stimulation Treatment for Depression. JAMA Psychiatry. 2021;78(3):337–339. doi:10.1001/jamapsychiatry.2020.3794Jannati, A., Oberman, L.M., Rotenberg, A. et al. Assessing the mechanisms of brain plasticity by transcranial magnetic stimulation. Neuropsychopharmacol. 48, 191–208 (2023). https://doi.org/10.1038/s41386-022-01453-8Pitcher, D., Parkin, B., & Walsh, V. (2021). Transcranial magnetic stimulation and the understanding of behavior. Annual Review of Psychology, 72, 97-121. https://doi.org/10.1146/annurev-psych-081120-013144Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Study (n.d.) https://www.nimh.nih.gov/funding/clinical-research/practical/stard
Measles cases are rising in Texas and New Mexico, with most infections occurring in unvaccinated individuals and public health officials warning of further spread. A new study in JAMA Psychiatry found that semaglutide significantly reduces alcohol craving and heavy drinking, suggesting a potential new treatment for alcohol use disorder. Research confirms that self-sampling for HPV is as effective as speculum-based exams, improving accessibility for women with disabilities and underserved populations. With the FDA's recent approval, self-collection could revolutionize cervical cancer screening in the U.S.
Interview with Jonathan Cantor, PhD, author of Changes in Specialty Crisis Services Offered Before and After the Launch of the 988 Suicide and Crisis Lifeline. Hosted by John Torous, MD. Related Content: Changes in Specialty Crisis Services Offered Before and After the Launch of the 988 Suicide and Crisis Lifeline
Interview with Jayani Jayawardhana, PhD, author of Association of State Cannabis Legalization With Cannabis Use Disorder and Cannabis Poisoning. Hosted by John Torous, MD, MBI. Related Content: Association of State Cannabis Legalization With Cannabis Use Disorder and Cannabis Poisoning
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-409 Overview: Listen in as we discuss how bright light therapy extends beyond seasonal affective disorder, potentially offering benefits for nonseasonal depression. Learn how to counsel patients effectively on its use and integrate this treatment into your practice, enhancing patient care and broadening treatment strategies for depression. Episode resource links: Menegaz de Almeida A, Aquino de Moraes FC, Cavalcanti Souza ME, Cavalcanti Orestes Cardoso JH, Tamashiro F, Miranda C, Fernandes L, Kreuz M, Alves Kelly F. Bright Light Therapy for Nonseasonal Depressive Disorders: A Systematic Review and Meta-Analysis. JAMA Psychiatry. 2024 Oct 2:e242871 Guest: Alan M. Ehrlich, MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-409 Overview: Listen in as we discuss how bright light therapy extends beyond seasonal affective disorder, potentially offering benefits for nonseasonal depression. Learn how to counsel patients effectively on its use and integrate this treatment into your practice, enhancing patient care and broadening treatment strategies for depression. Episode resource links: Menegaz de Almeida A, Aquino de Moraes FC, Cavalcanti Souza ME, Cavalcanti Orestes Cardoso JH, Tamashiro F, Miranda C, Fernandes L, Kreuz M, Alves Kelly F. Bright Light Therapy for Nonseasonal Depressive Disorders: A Systematic Review and Meta-Analysis. JAMA Psychiatry. 2024 Oct 2:e242871 Guest: Alan M. Ehrlich, MD, FAAFP Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com