Podcasts about drug administration

Don't miss the free live hydrogen workshop with Kashif. Save your seat at https://midlifeconversations.com/hydrogen  What if every biohack you've tried has been missing the one piece that actually makes it work? Red light, peptides, cold plunges, NAD, wellness IVs. You've tried some of them. Some worked. Some didn't. And here's the maddening part: your friend is thriving on the same protocol that made you feel worse. That's not random, and you're not broken. There's a reason, and it's rooted in your unique biology in ways most practitioners never explain. In this episode, I sit down with Kashif Khan, founder of The DNA Company and someone I genuinely call my health guru. Kashif healed himself from a cascade of chronic conditions including eczema so severe his eye was sealed shut, psoriasis, gut issues, migraines, and depression, all by going deep into functional genomics rather than accepting diagnoses and prescriptions. He now runs what may be the largest functional medicine clinic in the country by volume, working with the most complex cases imaginable. We cover what red light actually does inside your mitochondria and how you can completely overdo it, the real reason peptides cause side effects when used without proper sequencing, why 89% of your cholesterol score has nothing to do with food, and the one molecule Kashif keeps coming back to no matter who the patient is. We also go deep on why hydrogen tablets and bottles are not doing what you think they're doing and what the research actually shows it takes to move the needle. This is one of those conversations that makes you rethink everything. Listen all the way through. WE GO DEEP ON:  Why the same biohack transforms your friend but wrecks you What red light really does inside your cells and how to overdo it Why peptide order matters more than peptide choice Why 89% of your cholesterol score has nothing to do with food Why hydrogen has peer-reviewed studies on every chronic disease Hydrogen tablets vs. breathing: a tablet equals about 20 seconds How to rebuild the 70% of mitochondria you've lost since your 50s Cold plunges, saunas, PEMF, and wellness IVs: what's worth it and what isn't   Catch the full episode on YOUTUBE HERE: https://bit.ly/MidlifeConversationsYouTube   Learn More About Kashif Khan Instagram ➜ https://www.instagram.com/kashkhanofficial  Website ➜ https://midlifeconversations.com/hydrogen    Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com   Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit   For advertising inquiries: https://www.category3.ca/  Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen.  Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.  

This week we talk about LDL, HDL, and cardiovascular issues.We also discuss one-time therapies, statins, and pharmaceutical economics.Recommended Book: Blood by Dr. Jen GunterTranscriptCholesterol is the most common type of what's called a sterol, which is a type of steroid, but also structurally technically an alcohol. But functionally, and classified by scientists, cholesterol is a lipid, which in this case is similar to a fat in all but how the body uses it. Cholesterol is the type of sterol most commonly found in animals—other types are found in plants and fungi—and its function, and this is where it varies from fats, which are used to store energy, is to basically help hold the cell membrane together, and it also serves as an intracellular messenger.Cholesterol is especially prevalent in the brain and spinal cord of animals, but it's found throughout their bodily tissues, as well, and again, it's vital for holding everything together and helping things communicate, in addition to being a precursor for vitamin D, steroid hormones, and bile.You want to have cholesterol, then, as without it you would be dead.Too much cholesterol in the blood, however, can also make you dead, especially when it's bound to what's called low-density lipoprotein, or LDL, as that contributes to cardiovascular disease like heart attacks and aneurysms, which can massively impact one's overall wellness and quality of life, and at extremes lead to the whole system shutting down as a consequence of heart attack, stroke, and the like.A lot of things can contribute to the development of cardiovascular disease, including habits like smoking, genetic predisposition, and the enthusiastic consumption of alcohol and unhealthy foods. But high blood cholesterol, of the LDL variety, is one of the top contributors, as these low-density clusters of lipoprotein can clog the pathways that blood takes throughout our bodies. Other, denser types of lipoproteins, HDLs, can clear it, like a heavier, denser substance pushing through clogs of less-dense materials that are gumming up a pipe, but LDL is at times accumulated as a result of consuming delicious but unhealthy foods, which are hard to avoid, and for some people the only consistently available and affordable foods; and for other people LDL accumulates as a result of their genetic predispositions—two things that are devilishly difficult to change.What I'd like to talk about today is a new type of therapy that may be very good news for people who struggle with the accumulation of LDL, and why this is being seen as very good news more broadly, at the scale of entire nations, as well.—Pharmaceutical company Eli Lilly is testing a new, experimental drug called VERVE-102 which is a one-time infusion that is currently administered over the course of about four hours, and once completed, it turns off a gene called PCSK9, which is responsible for making a protein that regulates cholesterol levels in humans.As I said, this drug is still being tested, so these are early results. But in a study of 35 people with high cholesterol levels, high levels of LDL or LDL-C, which is short for lipoprotein cholesterol, they found that this infusion, which again, is a one-time treatment, so get it once and then theoretically at least you never have to get anything done ever again, it reduced those LDL and LDL-C levels by as much as 62%, and that reduction was maintained a year and a half after the infusion; that's how far out they're retested so far, and the hope is that each retest will continue to show the same.On the strength of those very promising results, a Phase 2 study has been planned by the end of 2026, and the US Food and Drug Administration, the FDA, previously fast-tracked this existing study, because of the promise and potential this drug already demonstrated in early studies; all of which is considered to be very significant progress and possibility.To understand that significance, though, it's useful to know some health stats. And I'm going to focus on the US here, as that's where this drug is being developed, but many wealthy countries have similar stats, at least in terms of cardiovascular disease struggles.As of 2024, which is the last year we had good, cohesive data on this in the US, it was estimated that about 11-12% of the US adult population has high cholesterol levels. This typically doesn't come with any symptoms, but it can contribute a higher risk for all those cardiovascular diseases, including heart attack and stroke. A further 86 million US adults have borderline or elevated cholesterol levels, which can easily tip higher, but also, even in that existing, elevated state, contribute to negative cardiovascular outcomes.There are treatments for high cholesterol, the most common of category of which are called statins, which reduce the production of LDL by inhibiting an enzyme that produces cholesterol in the body.Unfortunately, these drugs do come with some usually minor side effects, which can cause patients to stop using them, and they have to be taken daily, ideally at the same time each day. That necessity for consistency leads to a lot of incorrect or incomplete usage, which reduces the effectiveness of these drugs. But it's also estimated that only about 54.5% of US adults who would benefit from statins are currently taking one—so that's people who could benefit and who have it prescribed, and then within that number are all the people who are taking this drug incorrectly or incompletely, reducing the effectiveness. So a relatively small number of people who should probably be on these things are getting the full benefit they offer because of the nature of the drug.And that's not great, because in the US alone, heart disease is the leading cause of death for pretty much every adult demographic; men, women, people of most racial and ethnic and economic groups, you name it, heart disease is the biggest threat to their lives.One US citizen dies every 34 seconds of some kind of cardiovascular condition, and as of 2023, 1 in every 3 deaths in the US was caused by the same, adding up to just over 919,000 people that year.Between 2021 and 2022, alone, the cost of services and medications related to heart disease added up to more than $168 billion; again, that's just in that period, and just in the US.And once more, these are ailments that are caused or heavily influenced by high levels of cholesterol, which are themselves amplified by common lifestyle choices, environmental factors that are hard for many people to avoid, and just by raw, dumb luck because of genetics.This treatment category, then, is being seen as a pretty big deal because a one-time infusion means those who receive it don't have to remember to take a pill every day at the same time, and won't experience those statin-based side-effects.It also means that people who are currently costing the medical system a bunch of money each year, because they need treatments for all the issues they suffer as a result of high cholesterol, will suddenly cost the system a lot less money, for treatments and medications. Not for nothing, their health and quality of life will likely improve as well. So in addition to having better, healthier outcomes personally, their cost to healthcare systems will drop.Eli Lilly's drug isn't the only one currently working its way through clinical trials, either.Amgen is working on a similar treatment, and Novartis and Ionis Pharmaceuticals have drugs that are even further along in the process, their medicines that cut heart attacks, strokes, and cardiovascular deaths could be approved by the FDA as soon as next year.There are a lot of caveats worth noting here, including that the science is still out as to whether this approach, silencing proteins that lead to the creation of more LDL and a similar substance called Lp(a)—which is more dangerous because it's stickier and thus more likely to get stuck in important blood pathways, and it's also more likely to be caused by genetics than lifestyle—the word is still out on whether reducing these things in the body actually reduces hearth attacks and stroke.Some people have had this particular risk variable dramatically reduced, but have still suffered from cardiovascular events, which raises the question of whether this path is the right one to take in trying to reduce this category of health issues; the correlation between LDL and heart attacks and strokes might not be a clear-cut as long assumed.There's also the issue of price. Drug-makers are economically incentivized to sell treatments over cures, because that means they can continue selling their product over time, potentially for the life of the patient, and a cure, in contrast, is a one-time hit that in theory should alleviate the need for future treatment.There's a chance, then, that the drug-makers will decide they need to make these one-hit treatments really, really expensive in order to make their R&D dollars back and to make the kinds of profits their investors expect from them. That could then reduce the potential audience for these treatments, even if they are effective, and could further slow their deployment and future research in this space.If these trials continue to go well, though, there's a good chance that this combination of similar but distinct treatment types will provide a more sustainable alternative to current options, and that, like the recent bogglingly rapid and widespread deployment of GLP-1 treatments for all sorts of issues, could lead to a new paradigm in this facet of the medical world.Show Noteshttps://en.wikipedia.org/wiki/Cholesterolhttps://en.wikipedia.org/wiki/Cardiovascular_diseasehttps://en.wikipedia.org/wiki/High_cholesterolhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10982736/https://www.cdc.gov/heart-disease/data-research/facts-stats/index.htmlhttps://www.who.int/health-topics/cardiovascular-diseases#tab=tab_1https://www.ama-assn.org/public-health/chronic-diseases/what-doctors-want-patients-know-about-high-cholesterolhttps://en.wikipedia.org/wiki/Statinhttps://pubmed.ncbi.nlm.nih.gov/42187087/https://abcnews.com/GMA/Wellness/new-drug-game-changer-people-high-cholesterol/story This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit letsknowthings.substack.com/subscribe

Fasting is powerful—but fasting alone isn't always enough. Episode #262

The Food and Drug Administration has approved a new active ingredient for sunscreens sold in the U.S. for the first time in nearly 30 years.

The U.S. Food and Drug Administration has elevated a recall of Alfredo sauce distributed in 41 states to its most serious classification after they say a supplier flagged an ingredient for possible Salmonella contamination. Sarah Kellen, a longtime personal assistant to sex trafficker Jeffrey Epstein, has disclosed for the first time that Epstein’s preferential treatment at the Palm Beach County jail may have been the result of him paying off Palm Beach sheriff’s deputies. Palantir has lost a legal bid to force a Swiss magazine to publish its responses to articles detailing how the country’s government repeatedly rejected its services, in a case that has renewed scrutiny of its technology. Please Like, Comment and Follow 'Philip Teresi on KMJ' on all platforms: --- Philip Teresi on KMJ is available on the KMJNOW app, Apple Podcasts, Spotify, YouTube or wherever else you listen to podcasts. -- Philip Teresi on KMJ Weekdays 2-6 PM Pacific on News/Talk 580 AM & 105.9 FM KMJ | Website | Facebook | Instagram | X | Podcast | Amazon | - Everything KMJ KMJNOW App | Podcasts | Facebook | X | Instagram See omnystudio.com/listener for privacy information.

If you have ever come back from Europe and thought, why do I feel BETTER over there, this episode is for you. Natalie and her husband Brooks just got back from one of the most incredible trips of their lives. Germany, Switzerland, Lake Como, Piedmont, Lake Lucerne, Basel and Heidelberg. And it was not just beautiful. It rearranged some things in their bodies that they want to break down for you. In this conversation we go through every stop on the route, why pasta in Italy feels different than bread in the US, why dairy in Europe digests so much better, the hormone shift Natalie had to make during the trip, the digestive enzymes that came with us to every single meal, and a quick mention of the EMF and quantum testing we did in a lab in Germany (saving the deep dive for a future episode). Grab a coffee. Take this one with us.   WE GO DEEP ON: •  Day one and two at the Vitale Hotel in Stuttgart (plus a quick mention of the EMF testing we did in the lab) •  The Porsche Museum •  Konstanz, Germany (the San Francisco vibe, the perfume hotel, the bratwurst) •  The Vignette Pass drive into Switzerland •  Grand Hotel Victoria and the 3-hour Lake Como boat tour •  Villa Madonna in Piedmont — lady bugs, crop rotation, and the WHY behind Italian wheat •  Seelisberg on Lake Lucerne, the prettiest place we have ever been •  Basel and the best hamburger of our lives •  Heidelberg gelato •  Why dairy in Europe digests so differently than US dairy •  MassZymes at every meal   EPISODE LINKS:  •  Leela Quantum Tech ➜  https://leelaq.com/?ref=nataliejill save with code NATALIEJILL •  Quantum Upgrade ➜ https://quantumupgrade.io/start use code NATALIEJILL for a free 15 day trial •  MassZymes ➜ https://bioptimizers.com/nataliejill use code NATALIEJILL for 15% off  •  The Patch Method ➜ https://www.thepatchmethod.com/pages/thepatchmethod-natalie-jill use code NATALIEJILL for 20% off your first order TIMESTAMPS: •  00:00 — Why we feel better in Europe (open) •  04:00 — Stuttgart + Vitale Hotel + naked day (+ quick EMF testing side note) •  12:00 — Porsche Museum and Konstanz •  22:00 — Drive into Switzerland + supplement routine + the hormone story •  30:00 — Lake Como and the boat tour •  40:00 — Piedmont, Villa Madonna, and why Italian wheat is different •  50:00 — Seelisberg, fluffy cows, and the T3 mistake •  58:00 — Basel hamburger + Heidelberg gelato •  63:00 — The dairy breakdown + closing reflections   Catch the full episode on YOUTUBE HERE: https://bit.ly/MidlifeConversationsYouTube   Thank you to our show sponsors:  MITOQ: Take control of healthy aging and longevity. Get 10% off using code NATALIEJILL at checkout on https://www.mitoq.com/  BIOPTIMIZERS: Get the digestive enzymes I take with every meal here https://www.bioptimizers.com/nataliejill  Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com   Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit   For advertising inquiries: https://www.category3.ca/  Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen.  Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.  

While we wait for the U.S to play their first game in the World Cup, Alex and Ethan discuss which teams they are rooting for. The U.S Food and Drug Administration has authorized the emergency use of a generic over-the-counter tablet to help treat the Screw Worm infestation in cattle. In Friday tradition, we discuss your first-world problems!

Why Wearing Sunscreen All Day May Be Doing More Harm Than Good for Women Over 40 In this thought-provoking episode, Angela Foster sits down with renowned beauty expert and author Liz Earle MBE to challenge conventional wisdom about sunscreen and sun exposure. Liz discusses why current public health messaging around universal, all-day SPF use might be too extreme, potentially robbing us of vital Vitamin D and other essential benefits of natural daylight. KEY TAKEAWAYS Many people assume they still get Vitamin D while wearing sunscreen. However, Liz points out that this only happens because most people apply it too thinly or miss spots.  Applying high SPF when it is completely unnecessary, like on a dark winter morning during an underground commute, is a sign that public health messaging has become too broad.  Our skin isn't just a physical barrier; it actively receives light and communicates with the body's immune system.  Exposing your skin to gentle, early-morning sunlight (when the UV index is low) acclimatizes it.  Medical professionals and researchers are beginning to speak out against extreme sun avoidance.  BEST MOMENTS "When people say, 'Yes, you get Vitamin D from the sun when you're using sunscreen,' yeah, because you're not using your sunscreen properly. You're actually allowing some of that UVB to come through the skin." "The worst thing that we can do is stay indoors all year and then rush out for our two-week summer beach holiday and fry ourselves on the beach... That's because our skin has not got used to the sunlight." "The skin is actually an organ of light reception. This is what we're just beginning to understand, that the skin has light receptors on it for reasons—they're signaling, it's not just blocking and keeping our insides intact." "I don't know if you take collagen supplements, I do, but actually by going out in early morning light, I'm telling my body to make more collagen. So it's preparing the skin." "He says that he thinks that we will look back at this time and our lack of sun exposure as being as damaging to our health as smoking." VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what's actually happening in your body — and how to fix it.

Today's episode is a fan-favorite rebroadcast of one of our most popular summer self-care episodes. Enjoy!If you're looking to simplify your physical self-care routine, this episode is for you. Friend, dragging through your to-do list with low energy, sore muscles, or mental fog doesn't have to be your norm. In this episode, I'm sharing how one powerful essential oil, peppermint, can refresh your entire physical self-care routine this summer. From natural headache relief to cooling your body down to soothing tired feet and sleep enhancement, peppermint essential oil is a game-changer for busy Christian women who need real solutions, fast. Don't miss this quick and simple way to care for your body, God's temple, without adding stress to your summer.Statements made in this episode have not been evaluated by the Food and Drug Administration. Products mentioned are not intended to diagnose, treat, cure, or prevent disease.Get Peppermint Essential Oil ⁠Here⁠!Recipes Mentioned in the Episode⁠Snacking Chocolate⁠Episodes Referenced⁠017 // Make These Four Common Essential Oils Part of Your Daily Routines to Enhance Your Mood and Productivity⁠⁠041 // Essential Oil Blends to Embrace Autumn in All of Your Daily Routines⁠Let's Connect:Email: ⁠⁠hello@p31virtues.com⁠⁠

Did you know a small sample of hair can reveal what three months of blood tests might miss? In episode 204, I'm sitting down with Dee Davidson, board-certified functional health practitioner and hormone health expert, to talk about the HTMA hair mineral test and why it's one of the most useful tools she uses with her clients. If you have Hashimoto's and you feel like something is still off despite normal labs, this episode is for you. In this episode, you'll learn: Why a blood test gives you a real-time snapshot but the HTMA shows your mineral reserves over three full months What the hair test actually measures, including fight-or-flight status, blood sugar patterns, adrenal load, and hidden stressors How to stop guessing at supplements and start understanding what your body actually needs Hit play and find out what your minerals have been trying to tell you.   CONNECT WITH DEE DAVIDSON Website: confidentlyloveyourself.com  Instagram: @confidently_love_yourself   JOIN THE HEALTH WITH HASHIMOTO'S COMMUNITY The Health with Hashimoto's community is on Skool: https://www.skool.com/health-with-hashimotos/about Find all links on my resource page: https://healthwithhashimotos.com/resources/   ABOUT THE PODCAST & ESTHER: The Health with Hashimoto's podcast will help you explore the root causes of your autoimmune condition and discover holistic solutions to address your Hashimoto's thyroiditis. It is hosted by Esther Yunkin, a registered nurse, holistic health educator, and Hashimoto's warrior.   This podcast is for informational and educational purposes. Please discuss any questions or concerns with your healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Products mentioned are not intended to diagnose, treat, cure or prevent any disease.

Nicotine use is rising in young people Nicotine use among youth and young adults is rising according to the Centers for Disease Control with nicotine pouch use by people under 21 nearly quadrupling from 2022 to 2025. Nicotine is the highly addictive chemical stimulant found in tobacco. In 2024, almost 8% of high schoolers said they had used an e-cigarette in the past month, and more than 2% had used nicotine pouches. Some place the rise in use on health influencers on social media, who say nicotine has natural benefits such as better focus or claim it can prevent Parkinson's and Alzheimer's disease. Others say nicotine is a better alternative to smoking tobacco, since its non-carcinogenic and comes in fun flavors like mint and now fruit, approved by the Food and Drug Administration last month. Even U.S. Health and Human Services director Robert F. Kennedy Jr. said last year that nicotine pouches are "probably the safest way to consume nicotine." But is there any safe way to consume nicotine? Many health experts are concerned about this reframing, and its impact on young people. On Thursday's "Sound of Ideas," we'll ask local public health officials about this trend and ask about the role of nicotine on our health. Guests:- David Margolius, M.D., Public Health Director, City of Cleveland- Erika Trapl, Ph.D., Behavioral Epidemiologist & Professor, Case Western Reserve University- Wendy Hyde, Ohio Regional Director, Preventing Tobacco Addiction Foundation/Tobacco21 & Assistant Professor, Baldwin Wallace University- Ernest Williams, Barber, Polished Professionals & Graduate, Freedom From Smoking The Menu: Food Trucks Summer is underway, and communities are coming together for neighborhood celebrations, outdoor events and local festivals. Food trucks have become a staple of many of those gatherings, offering everything from regional favorites to inventive new flavors. We'll take a closer look at Northeast Ohio's food truck scene and its growing popularity. This is the latest installment of The Menu, our biweekly segment all about Northeast Ohio food produced in partnership with Cleveland Magazine. Guests:- Matt Maroon, Owner, Happy Camper Bar Car- Isabella Sugar, Managing Partner, CLE Chicken Food Truck & Catering- Delicia Dixon, Owner, The Urban Wrap Co.- Daniel Subwick, Director, Parks and Recreation, City of South Euclid

Fumizer, LLC v. United States Food and Drug Administration

In the early 20th century, Neal's company Force of Life was investigated for fraud. But somehow, Neal managed to get through the scandal and went on to found a cosmetics company that became very successful. Research: “Can’t Find E. Virgil Neal.” New York Times. January 15, 1906. https://timesmachine.nytimes.com/timesmachine/1906/01/15/100496816.pdf?pdf_redirect=true&ip=0 “Claimed to Raise the Dead.” Kansas City Star. Jan. 13, 1906. https://www.newspapers.com/image/653825670/?match=1&terms=%22Claimed%20to%20raise%20the%20dead%22 Conroy, Mary Schaeffer. “The Cosmetics Baron You’ve Never Heard Of: E. Virgil Neal and Tokalon.” Third Edition. Altus History Publishing. 2014. “E. Virgil Neal Passes Away at Geneva June 30.” The Sedalia Democrat. July 3, 1949. https://www.newspapers.com/article/the-sedalia-democrat-e-virgil-neal-obit/185827307/ “False Advertising Chief ‘Stimulant’ in Nixated Iron.” New York Tribune. Dec. 16,1917. https://www.newspapers.com/image/894241833/?terms=%22e.%20virgil%20neal%22 “Force of Life Charges Dismissed.” Buffalo News. April 24, 1906. https://www.newspapers.com/image/329115069/ “FORCE OF LIFE'S WIND-UP.; E. Virgil Neal Still Missing, but Offices Are Being Dismantled.” New York Times. Jan. 17, 1906. https://www.nytimes.com/1906/01/17/archives/force-of-lifes-windup-e-virgil-neal-still-missing-but-offices-are.html “Force of Lifers Sent Many Decoy Letters.” New York Times. February 7, 1906. https://timesmachine.nytimes.com/timesmachine/1906/02/07/101765677.pdf?pdf_redirect=true&ip=0 “Here’s a Hyopnotic Bank.” New York Sun. March 3, 1903. https://www.newspapers.com/image/207217198/?match=1&terms=Columbia%20Scientific%20academy “How Force of Lifers Did a Rush Business.” New York Times. Jan. 15, 1906. https://timesmachine.nytimes.com/timesmachine/1906/01/15/100496815.pdf?pdf_redirect=true&ip=0 “James R. O’Beirne.” Fordham University. Office of the President. https://www.fordham.edu/about/leadership-and-administration/administrative-offices/office-of-the-president/about/hall-of-honor/james-r-obeirne/ “Jury Disagrees Cartilage Case.” Buffalo Courier Express. May 5, 1918. https://www.newspapers.com/image/352806300/?match=1&terms=%22e.%20virgil%20neal%22 “Medical Mail-order Frauds.” American Medical Association. 1915. Accessed online: https://books.google.com/books?id=Cyq6AAAAIAAJ&vq=neal&source=gbs_navlinks_s “Medicine: From Sedalia.” Time Magazine. Dec. 25, 1933. https://content.time.com/time/subscriber/article/0,33009,746617-1,00.html “A Message to the Sick.” Rochester Democrat and Chronicle. Feb. 9, 1900. https://www.newspapers.com/image/135238292/?match=1&terms=vitaopathy “Most Beautiful Woman in Paris.” The Times-Union. October 6, 1909. https://www.newspapers.com/image/1278623430/?match=6&terms=To-Kalon Neal, E. Virgil and John H. Moore. “Modern Illustrative Banking.” American Book Company. 1904. Accessed online: https://archive.org/details/modernillustrati00neal/modernillustrati00neal/ Neal, E. Virgil and C.T. Craig. “Modern Illustrative Bookkeeping.” American Book Company 1901. Accessed online: https://archive.org/details/illustratimodern00nealrich/page/16/mode/2up “Neal, of ‘Nuxated Iron’ Fame, Held on Fraud Charge.” Times-Transcript. April 15, 1918. https://www.newspapers.com/image/1106273916/?match=1&terms=%22Neal%20of%20Nuxated%20Iron%22 “Neal Returns for Business.” Post-Standard. April 30, 1906. https://www.newspapers.com/image/1091107180/ Bennet, James. “Tokalon.” Cosmetics and Skin. Jan. 26, 2025. https://cosmeticsandskin.com/companies/tokalon.php “Gigantic Swindle Probably Bared.” Nebraska City Weekly. Jan. 16, 1906. https://www.newspapers.com/image/728074626 “In Force of Life Case.” Houston Post. Jan 13, 1907. https://www.newspapers.com/image/94975109 “Nuxated Iron Sellers in Libel Suit.” The Times-Transcript. June 10, 1918. https://www.newspapers.com/image/1106285753/?match=1&terms=%22e.%20virgil%20neal%22 “Part I: The 1906 Food and Drugs Act and Its Enforcement.” U.S. Food and Drug Administration. https://www.fda.gov/about-fda/changes-science-law-and-regulatory-authorities/part-i-1906-food-and-drugs-act-and-its-enforcement “Personal Magnetism.” San Francisco Examiner. March 8, 1903. https://www.newspapers.com/image/457762995/?match=1&terms=Columbia%20Scientific%20academy “Pope Receives O’Beirne.” New York Times. Sept 25, 1910. https://www.newspapers.com/image/20505640/?match=1&terms=%22pope%20receives%20o%27beirne%22 Schwarcz, Joe, PhD. “The Prince of Quackery.” McGill Office for Science and Society. July 16, 2025. https://www.mcgill.ca/oss/article/pseudoscience-history/prince-quackery “Thought Waves Between ‘Em.” New York Sun. April 12, 1903. https://www.newspapers.com/article/new-york-herald-e-virgil-neal-and-the-a/185828789/ “Tribune’s Answer in Libel Suit Calls E. Virgil Neal a Quck.” New York Tribune. June 23, 1918. https://www.newspapers.com/image/469171423/?match=1&terms=%22e.%20virgil%20neal%22 “Vain Search for Neal.” New York Times. January 16, 1906. https://timesmachine.nytimes.com/timesmachine/1906/01/16/101763032.pdf?pdf_redirect=true&ip=0 “WORRIED ABOUT NEAL & CO.: Depositors, You See, Don’t Like Hypnotism in Banking.” New York Sun. March 4, 1903. https://www.newspapers.com/article/new-york-herald-e-virgil-neal-hypnotic/176427712/ See omnystudio.com/listener for privacy information.

It's Wednesday, June 10th, A.D. 2026. This is The Worldview in 5 Minutes heard on 140 radio stations and at www.TheWorldview.com. I'm Adam McManus. (Adam@TheWorldview.com) By Jonathan Clark Hindu mob injured 25 Christians during worship service A Hindu mob attacked a Christian worship service in central India last week. The mob injured at least 25 people, including the pastor's pregnant wife. Such attacks are becoming more common in the country's state of Chhattisgarh.  The state's government passed a law criminalizing conversion in March. It is India's second most oppressive state for Christians. Open Doors ranks the whole country as the 12th most oppressive in the world for Christians.    7.8-magnitude earthquake struck Philippines A 7.8-magnitude earthquake struck off the coast of the southern part of the Philippines on Monday. The quake killed at least 37 people, injured nearly 500, and displaced over 32,000. Christians in the area are jumping into action. International Christian Concern reports, “Local churches have opened their doors and converted their sanctuaries into vital emergency evacuation centers, providing safe shelter, immediate access to drinking water, and essential family food packs to thousands of displaced and traumatized residents.”   In Matthew 5:7, Jesus said, “Blessed are the merciful, for they shall obtain mercy.” Spanish Anglican church joins Bible-believing Anglican denomination In Spain, the Evangelical Anglican Community of Valencia joined the Global Anglican Communion last week. It's the first church in the country to do so. The Global Anglican Communion is a movement of conservative Anglicans led by churches in the Global South. The group rejects the leadership of the Church of England which has shown support for sexually perverted lifestyles. Julian Milson is the pastor of the church in Valencia. He told Evangelical Focus, “We believe that the Church is called to submit to the authority of Scripture above any cultural pressure.” FDA launched safety study of Abortion Kill Pill In the United States, the Food and Drug Administration launched a safety study of the Abortion Kill Pill, reports The Wall Street Journal.  This comes a year after the Trump administration promised to review the dangers of the abortion drug Mifepristone. The drug is not only part of ending the lives of unborn babies, it also poses health risks to the mothers who take it.  Republican Senator Josh Hawley of Missouri introduced legislation in March to ban the Abortion Kill Pill. Listen to his comments. HAWLEY: “It is time for Congress to give the victims, the survivors -- many of whom are here today -- the right to recover against this company that has inflicted harm on them solely for the purpose of making profits. I'm introducing legislation today that will do just that. And I'm delighted to have with me here today great advocates for women's health and for life.” FBI fired analysts who targeted Catholics under President Biden         MS Now reports that the FBI fired several intelligence analysts who targeted Catholics under the Biden administration. The analysts were involved in a 2023 memo which revealed how the FBI was surveilling Catholics as potential domestic threats.  A recent report from the Justice Department stated, “The Biden Administration's policies regularly clashed with a Christian worldview and burdened traditional religious practices.” Amazon dethroned Walmart Amazon has dethroned Walmart as the largest corporation in the U.S. by revenue. That's according to the Fortune 500 rankings for 2026. Walmart came in second, ending its 13-year reign at the number one spot. Other top 10 companies include UnitedHealth Group, Apple, Alphabet, CVS Health, and Exxon Mobil.  Also, Texas dethroned California as the state with the most Fortune 500 companies this year.  Curaçao soccer player shared Christian testimony And finally, soccer teams from around the world are about to compete for the 2026 FIFA World Cup. The international men's soccer championship is being hosted across the United States, Mexico, and Canada this year. One of teams hails from Curaçao, an island county in the Caribbean. Players from the national team participated in a Christian worship event ahead of the competition.  The team's striker, Kenji Gorré, shared his testimony at the event. Listen. GORRE: “I received Him as my Savior, because I knew that my good works couldn't do enough. I thought that if you're a good person, you'll make it to Heaven. I thought if you're a good person, God will forgive me. He's a loving God. But the love of God goes deeper. “And that's when I heard the true Gospel of Jesus dying for my sins on the cross, bleeding for me, washing me, cleaning me. And He cleaned me from the inside out. But I thank Jesus every single day. And from that day I've never stopped seeking Him.” Gorré also said, “Tonight we don't gather as athletes seeking worldly success, but as children of God who recognize that everything we have belongs to Him.” 1 John 2:15 and 17 says, “Do not love the world or the things in the world. … The world is passing away, and the lust of it; but he who does the will of God abides forever.” Close And that's The Worldview on this Wednesday, June 10th, in the year of our Lord 2026. Subscribe for free by Spotify, Amazon Music, or by iTunes or email to our unique Christian newscast at www.TheWorldview.com. Plus, you can get the Generations app through Google Play or The App Store. I'm Adam McManus (Adam@TheWorldview.com). Seize the day for Jesus Christ.

This is the conversation I have been waiting to have. If you are doing the breathwork, the meditation, the supplements, the protocols, and you are STILL feeling anxious, inflamed, bloated, and exhausted, this episode will explain why. My guest is Dr. Pedram Shojai, The Urban Monk. He is a New York Times bestselling author and a Doctor of Oriental Medicine, and the man who first came on this show talking about stress and the nervous system. Years later, after a wild full-circle moment in a group coaching call, we are back together to talk about what he is doing NOW: the connection between the nervous system and the oral and gut microbiomes. In this episode we connect every dot for the midlife woman who has been told she is fine. The stress-and-biome loop. Why your mouthwash may be sabotaging you.  If you have been guessing about your gut and oral health and throwing supplements at a problem you have never tested, this is your invitation to stop guessing. WE GO DEEP ON: •  The full-circle story from The Urban Monk to the microbiome •  Why nervous system work alone is not enough in midlife •  The stress + biome loop and how it makes anxiety, fog, and bloat worse •  Oral microbiome 101: what it is and why it matters for your gut, heart, and brain •  The everyday things women are doing that are wrecking their oral biome •  Why generic probiotics often do not work •  Gut testing and oral microbiome testing demystified •  Pedram's personal first steps after seeing his own data •  Your this-week starter plan: 3 things to stop, 3 things to start TIMESTAMPS: •  00:00 — Cold open: the full-circle story •  03:00 — Welcome + context for midlife women •  05:00 — From The Urban Monk to the microbiome (his journey) •  13:00 — The nervous system + biome loop •  21:00 — Oral microbiome 101 •  29:00 — Gut microbiome as the control center •  36:00 — Stop guessing, start testing •  42:00 — Pedram's own protocol •  48:00 — Biome + hormones + your starter plan + hope   Catch the full episode on YOUTUBE HERE: https://bit.ly/MidlifeConversationsYouTube   Learn More About Dr. Pedram Shojai Instagram ➜ https://www.instagram.com/drpedramshojai/ Website ➜ http://midlifeconversations.com/oral    Thank you to our show sponsors:  MITOQ: Take control of healthy aging and longevity. Get 10% off using code NATALIEJILL at checkout on https://www.mitoq.com/  QUANTUM UPGRADE: Try Quantum Upgrade completely free for 15 days—no credit card required. Use code NATALIEJILL at checkout on https://quantumupgrade.io/start  BONCHARGE: Get glowing, younger looking skin with minimal effort or time. Go to http://boncharge.com/ and use code NATALIEJILL to save 15%  Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com   Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit   For advertising inquiries: https://www.category3.ca/  Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen.  Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.  

Success is about far more than the number on the scale. Episode #261

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E. Virgil Neal’s career started out with writing successful textbooks, but then took a turn into being a stage hypnotist and then a series of dicey mail-order businesses. Research: “Can’t Find E. Virgil Neal.” New York Times. January 15, 1906. https://timesmachine.nytimes.com/timesmachine/1906/01/15/100496816.pdf?pdf_redirect=true&ip=0 “Claimed to Raise the Dead.” Kansas City Star. Jan. 13, 1906. https://www.newspapers.com/image/653825670/?match=1&terms=%22Claimed%20to%20raise%20the%20dead%22 Conroy, Mary Schaeffer. “The Cosmetics Baron You’ve Never Heard Of: E. Virgil Neal and Tokalon.” Third Edition. Altus History Publishing. 2014. “E. Virgil Neal Passes Away at Geneva June 30.” The Sedalia Democrat. July 3, 1949. https://www.newspapers.com/article/the-sedalia-democrat-e-virgil-neal-obit/185827307/ “False Advertising Chief ‘Stimulant’ in Nixated Iron.” New York Tribune. Dec. 16,1917. https://www.newspapers.com/image/894241833/?terms=%22e.%20virgil%20neal%22 “Force of Life Charges Dismissed.” Buffalo News. April 24, 1906. https://www.newspapers.com/image/329115069/ “FORCE OF LIFE'S WIND-UP.; E. Virgil Neal Still Missing, but Offices Are Being Dismantled.” New York Times. Jan. 17, 1906. https://www.nytimes.com/1906/01/17/archives/force-of-lifes-windup-e-virgil-neal-still-missing-but-offices-are.html “Force of Lifers Sent Many Decoy Letters.” New York Times. February 7, 1906. https://timesmachine.nytimes.com/timesmachine/1906/02/07/101765677.pdf?pdf_redirect=true&ip=0 “Here’s a Hyopnotic Bank.” New York Sun. March 3, 1903. https://www.newspapers.com/image/207217198/?match=1&terms=Columbia%20Scientific%20academy “How Force of Lifers Did a Rush Business.” New York Times. Jan. 15, 1906. https://timesmachine.nytimes.com/timesmachine/1906/01/15/100496815.pdf?pdf_redirect=true&ip=0 “James R. O’Beirne.” Fordham University. Office of the President. https://www.fordham.edu/about/leadership-and-administration/administrative-offices/office-of-the-president/about/hall-of-honor/james-r-obeirne/ “Jury Disagrees Cartilage Case.” Buffalo Courier Express. May 5, 1918. https://www.newspapers.com/image/352806300/?match=1&terms=%22e.%20virgil%20neal%22 “Medical Mail-order Frauds.” American Medical Association. 1915. Accessed online: https://books.google.com/books?id=Cyq6AAAAIAAJ&vq=neal&source=gbs_navlinks_s “Medicine: From Sedalia.” Time Magazine. Dec. 25, 1933. https://content.time.com/time/subscriber/article/0,33009,746617-1,00.html “A Message to the Sick.” Rochester Democrat and Chronicle. Feb. 9, 1900. https://www.newspapers.com/image/135238292/?match=1&terms=vitaopathy “Most Beautiful Woman in Paris.” The Times-Union. October 6, 1909. https://www.newspapers.com/image/1278623430/?match=6&terms=To-Kalon Neal, E. Virgil and John H. Moore. “Modern Illustrative Banking.” American Book Company. 1904. Accessed online: https://archive.org/details/modernillustrati00neal/modernillustrati00neal/ Neal, E. Virgil and C.T. Craig. “Modern Illustrative Bookkeeping.” American Book Company 1901. Accessed online: https://archive.org/details/illustratimodern00nealrich/page/16/mode/2up “Neal, of ‘Nuxated Iron’ Fame, Held on Fraud Charge.” Times-Transcript. April 15, 1918. https://www.newspapers.com/image/1106273916/?match=1&terms=%22Neal%20of%20Nuxated%20Iron%22 “Neal Returns for Business.” Post-Standard. April 30, 1906. https://www.newspapers.com/image/1091107180/ Bennet, James. “Tokalon.” Cosmetics and Skin. Jan. 26, 2025. https://cosmeticsandskin.com/companies/tokalon.php “Gigantic Swindle Probably Bared.” Nebraska City Weekly. Jan. 16, 1906. https://www.newspapers.com/image/728074626 “In Force of Life Case.” Houston Post. Jan 13, 1907. https://www.newspapers.com/image/94975109 “Nuxated Iron Sellers in Libel Suit.” The Times-Transcript. June 10, 1918. https://www.newspapers.com/image/1106285753/?match=1&terms=%22e.%20virgil%20neal%22 “Part I: The 1906 Food and Drugs Act and Its Enforcement.” U.S. Food and Drug Administration. https://www.fda.gov/about-fda/changes-science-law-and-regulatory-authorities/part-i-1906-food-and-drugs-act-and-its-enforcement “Personal Magnetism.” San Francisco Examiner. March 8, 1903. https://www.newspapers.com/image/457762995/?match=1&terms=Columbia%20Scientific%20academy “Pope Receives O’Beirne.” New York Times. Sept 25, 1910. https://www.newspapers.com/image/20505640/?match=1&terms=%22pope%20receives%20o%27beirne%22 Schwarcz, Joe, PhD. “The Prince of Quackery.” McGill Office for Science and Society. July 16, 2025. https://www.mcgill.ca/oss/article/pseudoscience-history/prince-quackery “Thought Waves Between ‘Em.” New York Sun. April 12, 1903. https://www.newspapers.com/article/new-york-herald-e-virgil-neal-and-the-a/185828789/ “Tribune’s Answer in Libel Suit Calls E. Virgil Neal a Quck.” New York Tribune. June 23, 1918. https://www.newspapers.com/image/469171423/?match=1&terms=%22e.%20virgil%20neal%22 “Vain Search for Neal.” New York Times. January 16, 1906. https://timesmachine.nytimes.com/timesmachine/1906/01/16/101763032.pdf?pdf_redirect=true&ip=0 “WORRIED ABOUT NEAL & CO.: Depositors, You See, Don’t Like Hypnotism in Banking.” New York Sun. March 4, 1903. https://www.newspapers.com/article/new-york-herald-e-virgil-neal-hypnotic/176427712/ See omnystudio.com/listener for privacy information.

Most women in perimenopause are training hard, eating well, and still dealing with joint pain, stiffness, and injuries that never fully heal. Juliet Starrett, New York Times bestselling author and co-founder of The Ready State, joins me to reveal why the joint pain and stiffness so many women write off as ageing is actually a specific syndrome nobody warned you about. We get into what 30 minutes of floor sitting a day can do for your hips and low back, why most exercise routines are silently narrowing your range of motion, and the five weekly movement non-negotiables Juliet recommends for every woman over 40. WHAT YOU'LL LEARN • Why perimenopause triggers joint pain, frozen shoulder, and mobility loss • How 30 minutes of floor sitting a day rewires your hips and reduces pain• Best movement habits for women over 40 • How strength training may be stealing your flexibility over time • How to train through injury without making it worse • The HRV myth debunked and what to track instead VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what's actually happening in your body and how to fix it.

Special offer for Midlife Conversations listeners: https://puritywoods.com/nataliejill for up to 38% off - a special savings of $5 off each bottle of Dream Cream purchased and is the lowest savings you will find.  If you have ever turned a "clean" skincare bottle around, read the back, and not been able to pronounce a single ingredient, this episode is for you. The European Union has banned over 1,300 ingredients from skincare. The United States has banned 11. ELEVEN. So what are we actually putting on our faces every single day? And in midlife, when our hormones are already in flux, what are those ingredients doing to us? I sat down with Brian Vaszily (rhymes with PAISLEY), founder of TheArtofAntiAging.com and Purity Woods, who has spent over 25 years researching natural health and longevity. Brian is not a doctor. He is a researcher and educator who has worked alongside the most respected natural-health doctors of the last two decades. And he is here to tell us what is actually in our bathroom cabinets. I want to be really honest with you before we dive in: I am NOT 100% non-toxic. I still color my hair. There are products in my bathroom that are not clean. I am not preaching perfection. But what I DO take seriously is TOXIC LOAD, and that is the lens we go through this conversation with. We go DEEP on: Why your skin is an organ (the LARGEST one you have) and what that actually means for what you absorb The 1,300+ ingredients banned in the EU that are still legal in the US, including 9 commonly used ingredients Why the words "clean" and "natural" on a label mean absolutely NOTHING (zero regulatory definition) Endocrine disruptors and why they hit harder in menopause when our hormones are already shifting Parabens, phthalates, formaldehyde-releasers, oxybenzone, synthetic fragrance: what they do and how to spot them The "first 5 ingredients" rule that tells you 80% of what is actually in any product The truth about retinoids, niacinamide, and skin-lightening topicals like hydroquinone (banned across the developed world) Bakuchiol: the plant-based retinol alternative with comparable research The University of Rhode Island study on red maple leaf extract that researchers nicknamed "plant-based Botox" USDA Certified Organic on skincare: why it is the same federal standard as USDA Organic on food Can you layer Dream Cream with the products you already love? Yes, and how The 10-step bathroom audit you can do this WEEK to start lowering your toxic load TIMESTAMPS: 00:00. Why your skin is an organ (and what most labels are hiding) 06:00. EU banned 1,300+ ingredients. US banned 11. The full story. 18:00. Endocrine disruptors and why they hit harder in menopause 28:00. How to actually read a skincare label: the "first 5" rule 38:00. USDA Certified Organic: the only federal standard that means anything 45:00. Retinoids, niacinamide, and the truth about skin-lightening topicals 55:00. The maple leaf research and why Brian built Purity Woods 63:00. Can you layer Dream Cream with other products you love? 70:00. The 10-step bathroom audit you can do this week This is not a product pitch. This is a clean skincare education episode for midlife women who are tired of being lied to by labels.   Learn More About Brian Vaszily Instagram ➜ https://www.instagram.com/puritywoodsinc   Website ➜ http://puritywoods.com/nataliejill    Thank you to our show sponsors:  LEELA: Get 10% off your first Leela Quantum order with the code NatalieJill at checkout  at https://midlifeconversations.com/leela  Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com   Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit   For advertising inquiries: https://www.category3.ca/  Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen.  Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.

Whittling your diet down to five "safe" foods isn't healing your gut — it's masking a deeper imbalance that declining estrogen may be driving. Nutrition expert Cynthia Thurlow joins Angela Foster to unpack why so many women suddenly can't tolerate foods they once ate freely, and what's really happening behind the bloating, palpitations and brain fog. The conversation explores the link between estrogen loss and a leaky small intestine, the histamine-hormone "perfect storm" that can trigger hives and cramping, and why bloating during perimenopause is so often multifactorial. Cynthia also explains when bloating becomes a red flag worth investigating. You'll learn how to identify your personal food triggers without cutting entire food groups, why eating in a parasympathetic state matters, and which gut supports — from fibre and hydration to TUDCA — can help as progesterone and estrogen decline. If you've ever felt like your body suddenly turned against your favourite foods, this episode will help you understand why. KEY TAKEAWAYS Stop eliminating food groups as your default fix. Whittling your diet down to a handful of "safe" foods signals an underlying gut imbalance that needs support — not an ever-expanding exclusion list. Recognise food sensitivities as a likely leaky gut symptom. As estrogen declines it acts like failing "mortar" in the small intestinal lining, letting food particles leak into the bloodstream and provoke an immune response. Watch the histamine-estrogen "perfect storm." During high-estrogen days, loading up on high-histamine foods (leftovers, kombucha, fermented items) can trigger hives, congestion, cramping and diarrhoea — so keep histamine foods low or infrequent during those windows. Eat in a parasympathetic state. Sit at a table, remove distractions, and take four to five deep breaths before meals rather than eating standing, in the car, or on the move. Always get persistent bloating evaluated. Bloating from morning to night is different from bloating that appears after meals, and persistent symptoms should be checked because, in rare cases, they can signal something serious like ovarian cancer. QUOTES "The goal is to never get to a point where you're excluding entire classes of foods." "If we look at the small intestinal lining as like a brick and mortar system, the mortar is the estrogen." "I literally was talking to a podcast host and I broke out in hives head to toe because I was high estrogen, high histamine stress. And it was like the perfect storm." "It's not really that you need to cut out all these food groups. We just have a nuanced conversation. Don't go overboard with any one food." "I've just seen too many people blow off symptoms for a year or two that end up being bigger issues than they would have been had they been addressed up front." VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what's actually happening in your body — and how to fix it.

Are you still exhausted even though you're doing everything you can for your Hashimoto's? The problem might be something you literally cannot feel. Vitamin D is one of the most common root cause triggers for Hashimoto's, and most women have no idea their levels are low. You cannot feel it when your vitamin D is low. You cannot feel it when it is high. The only way to know is to test. And if your levels are not where they need to be, your immune system is missing one of its most important tools for calming down. In this episode, Esther breaks down why vitamin D is a root cause trigger for Hashimoto's, how it works in your immune system, and what you actually need to know about getting your levels up, whether that is through summer sun exposure or smart supplementation. In this episode, you will learn: Why vitamin D acts like a brake system for your immune system and what happens when those brakes fail What optimal vitamin D levels actually look like and why "not deficient" is not good enough How summer sun exposure works, why it is not as simple as going outside, and what to do about it year round Ready to map out all of your root causes? Hashimoto's Decoded: Root Causes Revealed walks you through the whole picture in under an hour, with a workbook to help you figure out your next step. https://healthwithhashimotos.com/hashimotos-decoded/   RELATED EPISODES: #9: Vitamin D and Autoimmune Disease #62: How to pick a vitamin D supplement   JOIN THE HEALTH WITH HASHIMOTO'S COMMUNITY Unlock your wellness journey with the free Health with Hashimoto's community! Join a supportive community that's here for you every step of the way. The Health with Hashimoto's community is on Skool: https://www.skool.com/health-with-hashimotos/about   Find all links on my resource page: https://healthwithhashimotos.com/resources/ ABOUT THE PODCAST & ESTHER: The Health with Hashimoto's podcast will help you explore the root causes of your autoimmune condition and discover holistic solutions to address your Hashimoto's thyroiditis. It is hosted by Esther Yunkin, a registered nurse, holistic health educator, and Hashimoto's warrior. This podcast is for informational and educational purposes. Please discuss any questions or concerns with your healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Products mentioned are not intended to diagnose, treat, cure or prevent any disease.

Mace and Jeff put Matt Walsh's antidepressant episode under the clinical microscope — and it does not pass the functional impairment test. They break down the 2022 Molecular Psychiatry umbrella review that dismantled the low-serotonin narrative, explain why that finding doesn't indict SSRIs as a category, and make the case that the “chemical imbalance” pitch was always more pharmaceutical advertising than clinical science. They also tackle what functional impairment actually means in diagnosis, the gender disparity in antidepressant prescribing, whether the SSRI-to-mass-violence argument is causal or just really committed to showing up in the same sentence, and what clinicians should actually be telling clients about medications they can't fully explain. For anyone who has ever explained serotonin to a client and quietly wondered if they knew what they were talking about: this one's for you. Music: “Machine Heart – Instrumental version” by Icarus. Licensed via Artlist Pro License #JeMO9k. Bielefeldt, A. Ø., Danborg, P. B., & Gøtzsche, P. C. (2016). Precursors to suicidality and violence on antidepressants: systematic review of trials in adult healthy volunteers. Journal of the Royal Society of Medicine, 109(10), 381–392. https://doi.org/10.1177/0141076816666805 Brody, D. J., & Gu, Q. (2020). Antidepressant use among adults: United States, 2015–2018. NCHS Data Brief, No. 377. https://www.cdc.gov/nchs/products/databriefs/db377.htm Chua, K. P., Volerman, A., Zhang, J., Hua, J., & Conti, R. M. (2024). Antidepressant dispensing to US adolescents and young adults: 2016–2022. Pediatrics, 153(3), e2023064245. https://doi.org/10.1542/peds.2023-064245 Healy, D., & Mangin, D. (2024). Post-SSRI sexual dysfunction: barriers to quantifying incidence and prevalence. Epidemiology and Psychiatric Sciences, 33, e44. https://doi.org/10.1017/S2045796024000441 Kuehner, C. (2017). Why is depression more common among women than among men? The Lancet Psychiatry, 4(2), 146–158. https://doi.org/10.1016/S2215-0366(16)30263-2 Moncrieff, J., Cooper, R. E., Stockmann, T., Amendola, S., Hengartner, M. P., & Horowitz, M. A. (2023). The serotonin theory of depression: a systematic umbrella review of the evidence. Molecular Psychiatry, 28, 3243–3256. https://doi.org/10.1038/s41380-022-01661-0 Salk, R. H., Hyde, J. S., & Abramson, L. Y. (2017). Gender differences in depression in representative national samples: Meta-analyses of diagnoses and symptoms. Psychological Bulletin, 143(8), 783–822. https://doi.org/10.1037/bul0000102 Stone, M., Laughren, T., Jones, M. L., Levenson, M., Holland, P. C., Hughes, A., Hammad, T. A., Temple, R., & Rochester, G. (2009). Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration. BMJ, 339, b2880. https://doi.org/10.1136/bmj.b2880

Does the history of drugs tell us something bigger about the world? That's what former Wired executive editor and UC Berkeley Senior Impact Fellow Thomas Goetz is betting on with his new podcast Drug Story. He joins Claudia to talk about how big drug breakthroughs have shaped how we live and what it will really take to build health in our society.Thomas and Claudia dive into:Fluoride: The paradox of public health success becoming invisibleWhy modern culture medicalizes ordinary human experiences like sleep, aging & energyHow public health needs to communicate differently, think bigger, and position itself as essential infrastructure for everyday healthThomas says the illusion of free will makes consumers feel like unhealthy choices are their choice alone:“There is some agency, like somebody decides to take a cigarette out of the pack. People decide whether to have a Coke instead of a glass of water or what have you. But there's also this vast machine, an invisible universe that is so powerful in compelling us from the commercials that are on our TV shows to the infrastructure of fast food in our neighborhoods. And it just is this easy inertia where oftentimes we don't actually have free will… We have much less free will than we think we do when it comes to things like what we eat, how we get our entertainment, where we live. There's a lot that is not really up to us and our choices.”Relevant LinksListen to Thomas Goetz's podcast Drug StoryAbout Our GuestsThomas Goetz is an award-winning science journalist and author. He has won National Magazine Awards (print and digital), Webby Awards, and FDA contracts. He created Drug Story as an Impact Fellow at the University of California Berkeley School of Public Health.The former Executive Editor at WIRED, he has worked at The Wall Street Journal, Inc., and the Robert Wood Johnson Foundation, and has written two award-winning books about technology and medicine. His writing has been selected for the Best American Science Writing and the Best American Technology Writing anthologies. He spent much of the past decade developing digital tools to help people make sense of prescription medications, including leading the development of openFDA for the Food and Drug Administration, and building an economic research team and editorial operations at GoodRx. You can reach him at thomas@drugstory.coSourceConnect With UsFor more information on The Other 80 please visit our website - www.theother80.com. To connect with our team, please email claudia@theother80.com and follow us on twitter @claudiawilliams and LinkedInSubscribe to The Other 80 on YouTube so you never miss our video extras or special video episodes!

Welcome back! Today, we are looking at Modafinil and it's nuanced use in psychiatry.References:Provigil (modafinil) [prescribing information]. North Wales, PA: Teva Pharmaceuticals USA, Inc. U.S. Food and Drug Administration. Available at: https://www.accessdata.fda.gov/drugsatfdadocs/label/2015/020717s037s038lbl.pdfSchwartz JR. Modafinil in the treatment of excessive sleepiness. Drug Des Devel Ther. 2009;2:71–85.Kaplan S, Goehring EL Jr, Engel T, et al. Cardiovascular outcomes associated with modafinil in patients with obstructive sleep apnea. Pharmacoepidemiol Drug Saf. 2018;27(11):1182–1190. doi:10.1002/pds.4642Cortese S, Adamo N, Del Giovane C, et al. Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and network meta-analysis. Lancet Psychiatry. 2018;5(9):727–738. doi:10.1016/S2215-0366(18)30269-4Goss AJ, Kaser M, Costafreda SG, Sahakian BJ, Fu CH. Modafinil augmentation therapy in unipolar and bipolar depression: a systematic review and meta-analysis of randomized controlled trials. J Clin Psychiatry. 2013;74(11):1101–1107. doi:10.4088/JCP.13r08560Bahji A, Mesbah-Oskui L. Comparative efficacy and safety of stimulant-type medications for depression: a systematic review and network meta-analysis. J Affect Disord. 2021;292:416–423. doi:10.1016/j.jad.2021.05.119Nunez NA, Singh B, Jorgensen A, et al. Efficacy and tolerability of adjunctive modafinil/armodafinil in bipolar depression: a meta-analysis of randomized controlled trials. Bipolar Disord. 2020;22(2):109–120. doi:10.1111/bdi.12859

Facelifts are having a MOMENT. Kris Jenner. Denise Richards. Suddenly every woman over 50 is asking the question out loud: is this what it takes now? Do I need a facelift? Is there a natural alternative that actually works? Facial plastic surgery jumped 19% in 2025. Forty-five percent of surgeons say menopause is what is driving it. Which means somebody needs to be telling us the REAL story, not the marketing one. This episode is with Dr. Anthony Youn, board-certified plastic surgeon known as America's Holistic Plastic Surgeon. He is the most-followed plastic surgeon on the internet with 13 million+ across TikTok and YouTube. He is the author of four bestsellers including Younger For Life and he hosts The Doctor Youn Show. Here is why he is different. He is a surgeon who tells women to AUTOJUVENATE before you operate. Skincare. Supplements. Collagen. Red light. Nutrition. Hormones. THEN, and only then, do we talk procedures. This is the honest midlife conversation about what works, what doesn't, and what is marketing. WE GO DEEP ON Why facelifts have gone mainstream and the Kris Jenner / Denise Richards effect SMAS vs. deep plane vs. ponytail lift, explained in plain English The natural stack that actually works BEFORE surgery (the autojuvenation method) When it IS actually time to consider surgery, and when to wait The simple 6-product skincare routine for every midlife woman Clean skincare: what is real, what is marketing fear Sunscreen truth: mineral vs. chemical, and the brands he actually recommends Collagen supplements: the research, the dose, what to look for on the label Red light therapy: does it actually work, and the masks worth the money Botox honestly: the 2025 CDC counterfeit warning and how to stay safe Filler, pillow face, and why we are in the anti-filler era BBL danger: the deadliest cosmetic surgery and how to lower the risk The ONE thing every midlife woman should do this week This is not a product pitch. This is the conversation that gives you control. TIMESTAMPS 00:00 — Facelifts have gone mainstream 18:00 — Simple skincare that actually works 32:00 — Collagen, red light, and what the research says 45:00 — Botox and filler, the honest truth 58:00 — BBL, autojuvenation, and the ONE thing this week Learn More About Dr. Anthony Youn Instagram ➜ https://www.instagram.com/tonyyounmd  Website ➜ http://dryoun.com  Podcast ➜ The Doctor Youn Show     Thank you to our show sponsors:  TIMELINE: Timeline is offering 20% off your order of Mitopure! Go to https://timeline.com/NATALIEJILL  KION: Kion is offering 20% off your order! Go to https://getkion.com/nataliejill  BONCHARGE: Get glowing, younger looking skin with minimal effort or time. Go to http://boncharge.com/ and use code NATALIEJILL to save 15%  Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com   Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit   For advertising inquiries: https://www.category3.ca/  Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen.  Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.  

Summer travel, holidays, BBQs, cruises, family gatherings, and social events can feel like a minefield when you're working to reverse insulin resistance. Episode #260

It's in the News! The top diabetes stories and headlines happening now. Top stories this week include: Afrezza inhaled Insulin is Approved for Kids, CGM + Ketone Monitor gets European approval, Food Coloring & Diabetes Study, Device Recalls include Omnipod and Dexcom, Beta Bionics shares more about their patch pump, ADA conference info and more! This podcast is not intended as medical advice. If you have those kinds of questions, please contact your health care provider. Announcing Community Commericals! Learn how to get your message on the show here. Learn more about studies and research at Thrivable here Please visit our Sponsors & Partners - they help make the show possible! Omnipod - Simplify Life All about Dexcom  All about VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Episode transcripts: Welcome! I'm your host Stacey Simms and this is an In The News episode.. where we bring you the top diabetes stories and headlines happening now. A reminder that you can find the sources and links and a transcript and more info for every story mentioned here in the show notes. ADA starts this week – safe travels to those of you heading to New Orleans. We'll be covering remotely so please follow on social – make sure to Like the FB page or join the group. We've got a wrap up episode planned for this podcast as well as some indepth interviews with the newsmakers from the conference. I will see some of you next week in Chicago. We have a couple of seats left for our Club 1921 dinner on June 10th in Northbrook – this is a FREE dinner for HCPs and patient leaders – all about screening for T1D. More info on the website under the events tab. Okay.. our top story this week: XX Afrezza inhaled insulin is now approved for kids and teens. The FDA okayed MannKind's afrezza for children 6 and older with type 1 and type 2 diabetes. MannKind says its proprietary Technosphere drug delivery platform enables the rapid absorption of insulin into systemic circulation. This follows FDA approval earlier this year for an update that revises recommendations for the starting mealtime dosage when patients switch from subcutaneous mealtime insulin regimens. MannKind also completed enrollment in February for a study evaluating the initiation of Afrezza therapy shortly after type 1 diabetes diagnosis in pediatric patients.   The company said it made Afrezza available for eligible patients for $35 or less per month. Desmond Schatz, professor of pediatrics at the University of Florida College of Medicine, said: "Mealtime insulin can be especially challenging for children because eating and snacking patterns, activity levels, and daily settings like school and sports often vary. With its rapid onset and dosing at the start of a meal, Afrezza may help clinicians better match insulin therapy to how children and families live day to day, while offering a needle-free mealtime option." Lots more to come on this – we're working on a bonus episode with one of the pediatric endos who worked on the clinical trials that led to this approval – hopefully have that out later this week. https://www.massdevice.com/mannkind-fda-approval-inhaled-insulin-children/ XX FDA has agreed to consider a new drug for the treatment of adults with type 1 and chronic kidney disease. Finerenone (fy-near-uh-known) is currently approved in the US for adults with CKD associated with type 2 diabetes and for adults with heart failure with left ventricular ejection fraction of 40% or greater. Chronic kidney disease (CKD) is present in over one-third of adults with diabetes, and because it's such a serious condition, interventions are needed to reduce its incidence and help people live a long and prosperous life. https://www.docwirenews.com/post/fda-grants-priority-review-to-finerenone-snda-for-type-1-diabetes-associated-ckd XX Abbot gets European approval for the world's first dual glucose‑ketone sensing technology for people with diabetes. They're calling this Libre Duo and Libre Duo 10 Day, and it's designed to continuously measure glucose and ketone levels every minute. Abbott plans to begin launching Libre Duo systems in select European countries later this year. Libre Duo delivers up to 15 days of wear and will be offered to adults ages 18 and older. Libre Duo 10 Day offers up to 10 days of wear and is intended for people ages 2 and older. Abbott is also working with leading pump companies to allow automated insulin delivery (AID) systems to connect with the sensors. https://abbott.mediaroom.com/2026-05-27-Abbott-secures-CE-Mark-for-worlds-first-dual-glucose-ketone-sensing-technology-for-people-with-diabetes   XX Huge recall for Omnipod. Insulin says a manufacturing issue through ongoing product monitoring that could result in insulin under-delivery  with specific lots of its Omnipod 5, Dash and Eros pods. Insulet said the scope of this action reaches approximately 7 million pods. This issue is separate from the March recall that affected certain Omnipod 5 lots. According to the Acton, Massachusetts-based company, some of its affected pods may have a small tear in the tubing (cannula) just above the skin. This tear lands between the pod and the point where the cannula enters the body. If this occurs, insulin may leak outside of the device instead of being fully delivered into the body as intended. This may lead to under-delivery of the therapeutic.   Individuals using an affected pod may notice wetness on the skin or pod adhesive or detect the smell of insulin. However, some cases may prove difficult to detect and go unnoticed. Of the approximately 7 million pods included in the action, approximately 60% have been consumed or are expired. The pods affected by the correction represent approximately 8.5% of the 2025 global Omnipod pod prodcution. Insulet says it has sufficient supply to replace affected pods. It expects no disruption to product availability. The company said it has notified the FDA and all other relevant regulatory authorities of its action.   The full list of affected pod lots can be found here. https://www.massdevice.com/insulet-another-omnipod-5-recall-dash-eros/ XX Dexcom is warning that certain scrapped glucose sensors have been stolen and resold. Dexcom said it has not received any reports of severe adverse events associated with the stolen product. One lot of scrapped devices carries a risk of infection for sensors that are not properly sterilized, and another lot had an elevated internal testing failure rate, meaning users would have an increased risk of having no sensor readings available. Dexcom said the affected sensors were stolen during the destruction process and then sold by third parties. The company routinely scraps sensors that do not meet its standards. The sensors are sent to a third-party vendor for destruction and recycling.   Dexcom said it traced sales of the stolen devices to Pharmsource, which is not an authorized Dexcom distributor but supplies some independent pharmacies and U.S. durable medical equipment distributors. Because of this, pharmacies that purchase products from Pharmsource should review their inventory, Dexcom said.   People with sensors from the affected lots should not use those sensors and can call customer support to request replacements. Dexcom has set up a website to help users check if their devices are affected. https://www.medtechdive.com/news/dexcom-warns-of-scrapped-glucose-sensors-being-resold/821139/ XX XX   Beta Bionics plans to debut its first insulin patch pump by the end of the second quarter of 2027, subject to Food and Drug Administration clearance. The device, called Mint, would be compatible with Beta Bionics' interoperable automated glycemic controller, a software that allows for the pump to automatically adjust insulin delivery based on readings from a glucose sensor. Beta Bionics first unveiled the prototype for Mint last year at the American Diabetes Association's Scientific Sessions. The device is expected to have a similar size and wear time, at three days, to Insulet's patch pumps on the market. It would have a 200-unit insulin reservoir.   Mint differs by containing a mix of reusable and disposable components. Beta Bionics plans to make the device exclusively available in the pharmacy channel, building on its existing agreements for its current iLet insulin pump. Beta Bionics is one of several diabetes tech companies developing patch pumps to compete with market leader Insulet. Tandem Diabetes Care and Medtronic spinoff MiniMed have also announced planned patch pumps. Tandem said it plans to file a 510(k) submission this quarter for a tubeless version of its small, durable pump, and Medtronic plans to submit its patch pump to the FDA this fall.   https://www.medtechdive.com/news/beta-bionics-to-launch-its-first-insulin-patch-pump-to-compete-with-insulet/821091/ XX CVS puts Zepbound back on it's coverage list – with it's Caremark PBM. They also added Foundayo, Lilly's obesity pill. CVS had dropped Lilly's Zepound last summer but kept competitor Wegovy. It'll be back at Caremark October first. All three of the nation's largest pharmacy ⁠benefit managers ​now cover Lilly's full obesity medicine portfolio. https://www.reuters.com/legal/litigation/cvs-brings-back-coverage-lillys-obesity-drug-zepbound-2026-05-28/   More to come, including a new benefit from metformin for women, something new from Tidepool, big news for T1D in Austalia and more.. XX A new study suggests that higher long-term exposure to food colouring additives — including both synthetic and natural colourings commonly found in processed foods and beverages — may be associated with an increased risk of developing type 2 diabetes. Researchers analyzed data from more than 108,000 adults in the French NutriNet-Santé cohort between 2009 and 2023, following participants for a median of just over eight years. During that time, 1,131 participants developed type 2 diabetes. The study found that people with the highest intake of total food colouring additives had a 38% higher risk of developing type 2 diabetes compared with non- or low-consumers.   Several specific additives were linked to increased risk, including caramel colouring additives such as total caramel (E150 family), plain caramel (E150a), sulphite ammonia caramel (E150d), and beta-carotene (E160a). Additional associations were observed for curcumin (E100), anthocyanins (E163), paprika extract (E160c), lutein (E161b), and cochineal-derived colourings (E120). "Our findings revealed positive associations between widely consumed food colouring additives and type 2 diabetes incidence," the authors wrote, adding that further research is needed to better understand the mechanisms behind the findings and whether food colouring regulations should be reevaluated. https://www.medscape.com/viewarticle/use-common-food-colours-tied-high-type-2-diabetes-risk-2026a1000hes XX Big news for Australia – their Therapeutic Goods Administration (TGA) approves Tzield. Tzield is now approved in Australia to delay the onset of stage 3 (or clinical) T1D in people aged eight years and older with stage 2 T1D – the early, pre-symptomatic stage of the condition, where changes in blood glucose levels have begun but insulin therapy is not yet required. Breakthrough T1D Australia Chief Executive Officer, Sydney Yovic, said the approval represented a transformational moment for Australians affected by T1D. https://newshub.medianet.com.au/2026/05/landmark-approval-of-tzield-in-australia-ushers-in-a-new-era-of-delay-for-type-1-diabetes/155036/ XX https://www.theatlantic.com/health/2026/05/diabetes-pregnancy/687324/ XX A common diabetes drug may hold great potential to help with aging, even if scientists aren't exactly sure why. According to a study, the drug metformin doesn't just help patients to effectively manage their type 2 diabetes. it may also give older women a better chance of living to 90. Scientists in the US and Germany used data from a long-term US study of postmenopausal women.   Records for a total of 438 people were selected – half of whom took metformin to treat diabetes, and half of whom took a different diabetes drug, sulfonylurea.   While there are some caveats and asterisks to the study, those in the metformin group were calculated to have a 30 percent lower risk of dying before the age of 90 than those in the sulfonylurea group. The study used age 90 as the marker for 'exceptional' longevity. However, scientists aren't yet sure that the drug extends lifespan, especially in humans – which is part of the reason for this study. RCTs could follow further down the line to dig deeper into these results, the researchers suggest. In the meantime, as the global population continues to skew older, studies continue to find ways to keep us healthier for longer and reduce damage to the body as we age. https://www.sciencealert.com/a-common-diabetes-drug-is-linked-with-exceptional-longevity-in-women XX The American Diabetes Association® (ADA) will host the 2026 Scientific Sessions from June 5-8 in New Orleans. The ADA's Scientific Sessions is the world's largest diabetes meeting, convening an expected audience of over 12,000 leading physicians, scientists, researchers, and healthcare professionals from around the globe. The premier diabetes meeting, which is also offered virtually, will feature the latest scientific findings in diabetes and obesity, where leading experts and peers will share findings in research for prevention, care, and cures at the Ernest N. Morial Convention Center. Key themes will include: Advancing obesity and metabolic health: Prevention, early detection, and disease modification: Improving cardiometabolic outcomes: Transforming care through innovation and access: New research will highlight how technology, artificial intelligence, and implementation strategies are reshaping diabetes care—reducing treatment burden, expanding access, and enabling more person-centered care. Advancing beta cell replacement and cure strategies: Fostering innovation: On Saturday, June 6, from 4:30-6:00 p.m., the Innovation Challenge, which debuted in 2023, invites emerging companies to pitch novel ideas to improve the lives of people living with diabetes. A panel of judges, with input from a live audience, determines which contestants will earn a private audience with potential funders. XX Tidepool, the nonprofit leader advancing innovation in diabetes technology, announced that Tidepool+ Direct Connect is now available through the Epic Showroom. Built on SMART on FHIR, Direct Connect brings interactive diabetes device data directly into Epic workflows, helping clinicians use patient data during routine care. "Tidepool has always focused on making diabetes data more accessible and actionable," said Brandon Arbiter, CEO. "We're excited to empower clinicians using Epic with insightful, intuitive patient data that fits directly into their encounter workflow so they can use it to improve care in the moment it matters."   Tidepool+ Direct Connect supports scalable deployment across Epic-enabled health systems. This architecture enables faster, more intuitive rollouts, enhancing Tidepool's existing EHR integration capabilities.   Direct Connect is part of Tidepool's ongoing work to improve how clinicians can use timely and relevant diabetes device data during patient visits to help drive better health outcomes.   The feature is now available in the Connection Hub of the Epic Showroom.   https://www.businesswire.com/news/home/20260527780274/en/Tidepool-Launches-in-Epic-Showroom-to-Bring-Diabetes-Device-Data-into-the-Point-of-Care XX

Bremelanotide (Vyleesi) was approved by the US Food and Drug Administration in 2019 as an on-demand subcutaneous injectable for the treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women. An editorial in the May-June 2026 issue of the Journal of Clinical Psychopharmacology suggests that the drug may hold promise for HSDD in men without testosterone deficiency but who have other disorders resulting from organic or psychogenic causes. Placebo-controlled and peer-reviewed studies would first be needed to confirm safety and efficacy in men.   The authors of the editorial are Dr. James G. Pfaus, PhD, a researcher from Charles University in Prague who specializes in the neurobiology of sexual behavior, and Dr. Richard Balon, MD, Associate Editor of this journal. Dr. Balon is on the faculty of Wayne State University School of Medicine in Detroit.   In this podcast, the authors discuss their editorial with Dr. Julia Ann Koretski, MD, who is JCP's Digital Editor and a staff psychiatrist at Newton-Wellesley Hospital in Massachusetts.   Article doi: 10.1097/JCP.0000000000002179

Have you ever looked at a diet protocol and immediately thought, "There is no way I can do that"? That was me with AIP. The restrictions felt overwhelming, the food felt foreign, and honestly, I was not sure the payoff was worth the stress. So when Mickey Trescott reached out about her new book, my first instinct was hesitation. Then I read it. And everything changed. In this bonus episode of Health with Hashimoto's, I'm sharing my honest review of The New Autoimmune Protocol by Mickey Trescott — and why I went from resistant to completely bought in. This is The New Autoimmune Protocol review I wish someone had given me years ago. Here's what you'll hear in this episode: Why AIP felt impossible before and what made it finally feel doable What the New AIP actually is — including the three phases and two flexible approaches that make it more accessible than the original What makes this book stand out, from the practical prep guidance to the gorgeous cookbook section Hit play and find out if this book belongs on your shelf.   Buy the book on Amazon or your local bookstore (affiliate link)   JOIN THE HEALTH WITH HASHIMOTO'S COMMUNITY Unlock your wellness journey with the free Health with Hashimoto's community! Join a supportive community that's here for you every step of the way. The Health with Hashimoto's community is on Skool: https://www.skool.com/health-with-hashimotos/about   Find all links on my resource page: https://healthwithhashimotos.com/resources/   ABOUT THE PODCAST & ESTHER: The Health with Hashimoto's podcast will help you explore the root causes of your autoimmune condition and discover holistic solutions to address your Hashimoto's thyroiditis. It is hosted by Esther Yunkin, a registered nurse, holistic health educator, and Hashimoto's warrior.   This podcast is for informational and educational purposes. Please discuss any questions or concerns with your healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Products mentioned are not intended to diagnose, treat, cure or prevent any disease.

Photo by Reproductive Health Supplies Coalition on Unsplash In June of 2022 in the case of Dobbs v. Jackson Women's Health Organization, the Supreme Court overruled Roe v.Wade on the basis that access to abortion is a state issue. Since that decision, some states have passed laws restricting or banning altogether women's access to abortion. But the Food and Drug Administration approved the distribution of Mifepristone for medical abortions without an in-person visit as a safe practice. Louisiana filed a lawsuit against the FDA for this action and at the end of April 2026, the Fifth Circuit Court of Appeals ruled in favor of Louisiana, restricting women's access to the drug in states that have banned abortions. On May 4th, the Supreme Court ordered a halt to stopping access to the drug until May 11th so that both sides could respond and the court could consider the issue more fully. HealthCetera host Diana Mason, PhD, RN, FAAN, discussed the case of Louisiana v. the FDA and the Fifth Circuit Court of Appeal's ruling with Anna Beernstein, principal federal policy advisor for the Guttmacher Institute, a research and policy organization committed to advancing sexual and reproductive health and rights worldwide. This interview first aired on HealthCetera in the Catskills on WIOX Radio on May 6, 2026. The post The Fifth Circuit Court of Appeals & Women’s Health appeared first on HealthCetera.

Why does Hashimoto's happen in the first place and what can you actually do about it? If you have been diagnosed and you are wondering what caused this, you are not alone. Most women with Hashimoto's are told what they have but not why they have it. That missing piece is exactly what this episode is about. In episode 202, Esther kicks off the Summer Root Cause Series by walking through the root causes of Hashimoto's, the three things every single person with an autoimmune condition has in common, and the eight most common triggers that can set the whole process in motion. In this episode, you'll learn: Why genetics load the gun but lifestyle and environment pull the trigger How leaky gut keeps your immune system working overtime and why an overworked immune system starts attacking things it shouldn't The eight most common Hashimoto's triggers and why knowing yours is the turning point Hit play and find out what's actually driving your Hashimoto's.   Hashimoto's Decoded: Root Causes Revealed: https://healthwithhashimotos.com/hashimotos-decoded/   Mentioned on this episode: #83 Best Supplements for Hashimoto's JOIN THE HEALTH WITH HASHIMOTO'S COMMUNITY Unlock your wellness journey with the free Health with Hashimoto's community! Join a supportive community that's here for you every step of the way. The Health with Hashimoto's community is on Skool: https://www.skool.com/health-with-hashimotos/about   Find all links on my resource page: https://healthwithhashimotos.com/resources/   ABOUT THE PODCAST & ESTHER: The Health with Hashimoto's podcast will help you explore the root causes of your autoimmune condition and discover holistic solutions to address your Hashimoto's thyroiditis. It is hosted by Esther Yunkin, a registered nurse, holistic health educator, and Hashimoto's warrior.   This podcast is for informational and educational purposes. Please discuss any questions or concerns with your healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Products mentioned are not intended to diagnose, treat, cure or prevent any disease.

Pennsylvania's unemployment rate held steady during the month of April. The jobs numbers show record highs in some industries.The U.S. Food and Drug Administration is considering adding a new ingredient to sunscreen products for the first time since 1999. Dermatologists are hopeful the new ingredient could expand options for sun protection. A new report released by the state Insurance Department could offer lawmakers a path forward to help struggling pharmacies. Twenty-six Pennsylvania high schools are receiving state grants to strengthen the pipeline of special education teachers. Pennsylvania will have a new state librarian later this week, beginning May 30th. And a deeper dive: Grocery stores typically have shopping carts that can fit a toddler, or even shopping carts that look like race cars where small kids can ride along. There are also motorized scooters for people with mobility issues. But there's also another type of shopping cart, one that advocates for people with disabilities say should be more widely available. 

Peptides are short chains of amino acids. GLP-1 weight loss drugs are peptides. Insulin is one, too. And there are thousands of others. Now, people are seeking out peptides in the hope of better muscles, better skin, better memory, better…everything. Many of the peptides people wanna try are available for research use only but the Food and Drug Administration might change this. In July, the agency could decide to make about a dozen peptides more accessible by allowing pharmacies to compound and distribute them Marketplace's Stephanie Hughes spoke with Zara Stone, tech culture reporter at The San Francisco Standard, to learn more.

Peptides are short chains of amino acids. GLP-1 weight loss drugs are peptides. Insulin is one, too. And there are thousands of others. Now, people are seeking out peptides in the hope of better muscles, better skin, better memory, better…everything. Many of the peptides people wanna try are available for research use only but the Food and Drug Administration might change this. In July, the agency could decide to make about a dozen peptides more accessible by allowing pharmacies to compound and distribute them Marketplace's Stephanie Hughes spoke with Zara Stone, tech culture reporter at The San Francisco Standard, to learn more.

We talk a lot on this show about supplements, hormones, food, sleep, and protocols. But there is a layer underneath all of that we have not gone deep on until now. Our beliefs. Who we think we are. Why we are here. And the quiet, unconscious story running the show every single day. In this episode, Natalie sits down with her own therapist Mcayla Sarno, an EMDR specialist who has spent almost twenty years helping women get to the root of the beliefs that are silently shaping their bodies, their relationships, their purpose, and their health. Natalie also shares the very personal EMDR story that changed her life. The memory with her mom in the car. The belief she did not even know she was carrying. And what shifted when she finally looked at it through different eyes. This is a real conversation about why so many of us hit midlife feeling lost, why the empty nest hits harder than anyone warned us, what is actually happening when we try to control everything, and why a therapist asking the right question will always do something ChatGPT cannot. We talk about how core beliefs form, how they show up in the body, and the work it takes to finally come home to who we have always been underneath all of it. If you have been feeling like you have done all the outer work and something inside still is not clicking, this is the episode for you. WE GO DEEP ON •  What EMDR actually is and why it is not just for trauma •  The difference between understanding something and integrating it •  How core beliefs form and why they generalize to every area of our life •  The connection between unresolved beliefs and chronic health issues •  Why ChatGPT will never replace a real therapist asking the right question •  The empty nest grief nobody talks about and the mini mourning of every version of our kids •  Why control feels safe but never actually makes us safe (and what does) •  How external validation becomes the trap of our 30s and 40s and breaks open in our 50s •  The infant question that reframes everything: were you good enough the day you were born •  Natalie's personal EMDR story, the car memory with her mom, and the belief she was carrying •  Why 5-day intensives work when weekly therapy has not •  "I always was. I already am." The reframe every midlife woman needs Learn More About Mcayla Sarno Instagram ➜ https://www.instagram.com/drmcayla  Website ➜ http://drmcayla.com/    Thank you to our show sponsors:  MITOQ: Take control of healthy aging and longevity. Get 10% off using code NATALIEJILL at checkout on https://www.mitoq.com/  LEELA QUANTUM: Get 10% off your first Leela Quantum order with the code NATALIEJILL at checkout  at https://midlifeconversations.com/leela   SUNLIGHTEN: Sleep better. Recover faster. Stress less. Get Sunlighten infrared saunas HERE https://sunlighten.com  and use code NATALIEJILL to save up to $1,400!    Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com   Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit   For advertising inquiries: https://www.category3.ca/  Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen.  Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.

Knowing what to do is not the same as being able to do it consistently. Episode #259 — Turbo Talk

Did someone send you this episode? Or maybe you've been living with Hashimoto's for a while and you're still not sure you fully understand what's actually happening in your body? Either way, you're in the right place. This episode covers the basics — what your thyroid does, what Hashimoto's really is, and why so many women are stuck even when their labs look "fine" and they're doing everything they're supposed to do. In episode 201, recorded in honor of World Thyroid Day, Esther breaks down exactly what your thyroid does, why Hashimoto's is more than a thyroid problem, and why missing the autoimmune piece means the attack on your thyroid never stops. In this episode, you'll learn: Why your thyroid affects every single cell in your body — and what happens when it's not producing or converting enough hormone The most common symptoms of hypothyroidism and why they show up differently for everyone Why Hashimoto's has two parts, and why missing the autoimmune piece means the attack on your thyroid never stops Hit play — and share this one with someone who needs to understand what you're going through.   Hashimoto's Decoded: Root Causes Revealed  - https://healthwithhashimotos.com/hashimotos-decoded/   Episodes Mentioned: Episode 38 about depression Episode 103: Thyroid labs to check   JOIN THE HEALTH WITH HASHIMOTO'S COMMUNITY Unlock your wellness journey with the free Health with Hashimoto's community! Join a supportive community that's here for you every step of the way. The Health with Hashimoto's community is on Skool: https://www.skool.com/health-with-hashimotos/about   Find all links on my resource page: https://healthwithhashimotos.com/resources/   ABOUT THE PODCAST & ESTHER: The Health with Hashimoto's podcast will help you explore the root causes of your autoimmune condition and discover holistic solutions to address your Hashimoto's thyroiditis. It is hosted by Esther Yunkin, a registered nurse, holistic health educator, and Hashimoto's warrior.   This podcast is for informational and educational purposes. Please discuss any questions or concerns with your healthcare professional. These statements have not been evaluated by the Food and Drug Administration. Products mentioned are not intended to diagnose, treat, cure or prevent any disease.

Your mouth has over 700 species of bacteria living inside it right now. And the balance of those bacteria is directly driving whether you have brain fog, bleeding gums, heart disease, or Alzheimer's. Nobody told us this. And nobody told us that in menopause, EVERYTHING about our mouth changes. Saliva drops. Gums get sensitive. Bone density falls. And the antibacterial mouthwash we have been using for 20 years? It might be making it worse. This episode is with Dr. Sanda Moldovan, an award-winning periodontist AND board-certified nutritionist, founder of Orasana, and author of Heal Up. She has spent two decades studying the oral microbiome and she is one of the most respected oral health experts in the country. She walks us through the THREE simple things we can do tonight to reset our oral biome. None of them are expensive. None of them are complicated. And the science is on her side. WE GO DEEP ON Why the mouth is the gateway to your whole body (heart, brain, joints, gut) The menopause mouth: why estrogen drops change your gums, saliva, and oral microbiome The 3 simple things to do tonight: electric brush, water floss, oral probiotic before bed Tongue scraping: 60% of your oral bacteria lives on your tongue Oil pulling: does it actually work, and the safety warning nobody mentions The mouthwash myth: how antibacterial rinses can raise your blood pressure The nitric oxide connection your dentist never told you about The labs to ask for: OralDNA salivary testing The red flags every midlife woman should stop ignoring 3 simple things you can start tonight that actually move the needle This is not a doom episode. This is the conversation that gives you control. TIMESTAMPS 00:00 — Oral microbiome 101 and the mouth-body connection 12:00 — The 3 simple things to do tonight 28:00 — The mouthwash myth and the nitric oxide story 42:00 — Nutrition for the mouth and the red flags to watch 56:00 — The biome reset and your 8-step starter protocol   Catch the full episode on YOUTUBE HERE: https://bit.ly/MidlifeConversationsYouTube   Learn More About Dr. Sanda Moldovan Instagram ➜ https://www.instagram.com/drsandamoldovan  Website ➜ http://drsandamoldovan.com      Thank you to our show sponsors:  BON CHARGE: Get glowing, younger looking skin with minimal effort or time. Go to http://midlifeconversations.com/boncharge and use code NATALIEJILL to save 15%  TIMELINE: Timeline is offering 20% off your order of Mitopure! Go to https://timeline.com/NATALIEJILL  Free Gifts for being a listener of Midlife Conversations! Mastering the Midlife Midsection Guide: https://theflatbellyguide.com/ Age Optimizing and Supplement Guide: https://ageoptimizer.com   Connect with me on social media! Instagram: www.Instagram.com/Nataliejllfit Facebook: www.Facebook.com/Nataliejillfit   For advertising inquiries: https://www.category3.ca/  Disclaimer: Information provided in the Midlife Conversations podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before making any changes to your current regimen.  Information provided in this podcast and the use of any products or services related to this podcast does not create a client-patient relationship between you and the host of Midlife Conversations or you and any doctor or provider interviewed and featured on this show. Information and statements may have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease. Advertising Disclosure: Some episodes of Midlife Conversations may be sponsored by products or services discussed during the show. The host may receive compensation for such advertisements or if you purchase products through affiliate links. Opinions expressed about products or services are those of the host and/or guests and do not necessarily reflect the views of any sponsor. Sponsorship does not imply endorsement of any product or service by healthcare professionals featured on this podcast.  

Fasting is not a switch — it's a sequence. Episode #258

President Donald Trump is arriving in Beijing today on a long-awaited trip – one that got delayed even further by Trump's war in Iran. It's Trump's second trip to China and his first in nearly a decade. It's also a trip where both sides see big opportunities (mostly to make money). But, the global balance of power has shifted – arguably, in China's favor. Trump is in the midst of an unpopular war with no clear exit plan and he's looking to make deals, not problems. Meanwhile, China has become an economic and military powerhouse more than able to stand up to the US and Trump's trade wars. So to talk more about Trump's trip to China and what's at stake, we spoke to Phelim Kine. He is the DC based China correspondent at POLITICO.And in headlines, Secretary of War/little boy Pete Hegseth returns to the Hill, Food and Drug Administration head Marty Makary steps down, and the What A Day newsletter investigates a new video game that parodies Trump's second term in office.Show Notes: Check out Phelim's work – politico.com/staff/phelim-kine Call Congress – 202-224-3121 Subscribe to the What A Day Newsletter – https://tinyurl.com/y4y2e9jy What A Day – YouTube – https://www.youtube.com/@whatadaypodcast Follow us on Instagram – https://www.instagram.com/crookedmedia/ For a transcript of this episode, please visit crooked.com/whataday

Dr. Marty Makary has resigned as commissioner of the Food and Drug Administration. Makary faced criticism over the FDA's rejections of rare-disease drugs, the agency's handling of abortion pills and high-profile departures of key FDA staff. But WSJ's Liz Essley Whyte reports that it was a battle over flavored vapes that sealed Makary's fate. Jessica Mendoza hosts. Further Listening: - The Flu Shot Drama at the FDA - The FDA Boss on the Agency's MAHA Makeover - How Puff Bar Became the Most Popular Vape for KidsSign up for WSJ's free What's News newsletter. Learn more about your ad choices. Visit megaphone.fm/adchoices