Podcasts about Mortality

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Turn online alignment into an offline community — join us at TheWayFwrd.com to connect with like-minded people near you.We obsess over food and supplements. Meanwhile, the light we live under every day is quietly wrecking our biology.In this episode, I sit down with Matt Maruca, founder and CEO of Ra Optics, to discuss how artificial light, blue light, and disrupted circadian rhythm quietly impact energy, sleep, and long-term health. Matt shares how a years-long personal health journey led him to study circadian biology and the essential role light plays in human physiology.We explore why modern indoor environments are so biologically mismatched, how LED lighting and screens affect mitochondrial health, and why sunlight is powerful but not something to mindlessly overdo. Matt also explains how light influences hormones, mental health, and recovery, and why most wellness conversations miss this entirely.Beyond the science, we touch on Matt's broader work teaching how to think differently about light exposure, health, and performance.If you're interested in biohacking, sleep optimization, blue light, or understanding why your nervous system feels constantly overstimulated, this episode will shift how you see your environment.You'll Learn:[00:00:00] Introduction[00:08:02] Matt's childhood health struggles, and the discovery that changed everything[00:12:23] Diet alone can't fix your health, so what is at the root of chronic disease?[00:16:34] The fourth phase of water inside your cells and why 40% of sunlight is designed specifically to structure it[00:18:33]  The devolution of artificial light — from fire-like incandescents to blue-heavy, infrared-stripped “junk light” LEDs[00:39:16] Blue light, your circadian rhythm and mental illness[00:45:22] Why "more sun is better" is wrong[00:57:15] How a chance encounter at an event turned a garage tinting operation into Ra Optics[01:13:19] Why traditional sunglasses blunt the health benefits of sunlight, and the lens innovation designed to fix that[01:20:58] What makes Ra Optics different from other blue light blocking glasses on the market[01:30:02] Why doing all the right things still left Matt miserable, and the event that created a huge shift[02:09:27] The hidden problems with "circadian bulbs" on the current market[02:20:12] How to protect your light environment and stay healthy while travelingResources Mentioned:The Way Forward episode on the Hidden Dangers of EMFs, Artificial Light, & Wifi (How To Avoid Them) featuring Tristan Scott | YouTubeThe Way Forward episode on Circadian Biology, Leptin, & Light featuring Sarah Kleiner | YouTubeThe Life Stylist episode on Extreme Biohacking: Millennial Edition with Matt Maruca | Listen NowA mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine by Wallace, D | ArticleThe Fourth Phase of Water by Gerald Pollack | Book or AudiobookThe Hard Thing About Hard Things by Ben Horowitz | Book or AudiobookThe Lean Startup by Eric Ries | Book or AudiobookThe 4-Hour Workweek by Timothy Ferriss | Book or AudiobookAutobiography of a Yogi by Paramhansa Yogananda | Book or AudiobookSouth: The ENDURANCE Expedition by Ernest Shackleton | Book or AudiobookSaunaSpace | WebsiteFind more from Matt:The Light Diet Podcast | Spotify or AppleThe Light Diet | InstagramRa Optics | InstagramFind more from Alec:Alec Zeck | InstagramAlec Zeck | XThe Way Forward | InstagramThe Way Forward is Sponsored By:New Biology Clinic: Redefine Health from the Ground UpExperience tailored terrain-based health services with consults, livestreams, movement classes, and more. Visit www.NewBiologyClinic.com and use code THEWAYFORWARD (case sensitive) for $50 off activation. Members get the $150 fee waived

TRUMP'S MORTALITY, EUROPEAN ALARM, AND THE BEAR TRAP Colleagues Gaius and Germanicus, Friends of History Debating Society, Londinium, 91 AD. Focusing on "Emperor" Trump, the speakers argue his recent threats against Venezuelan leadership display the "mortality" and "incoherence" of age, exacerbated by the office's "transmogrification" of the individual which detaches them from reality. This aggression alarms European allies, who view the extraction operation as "kidnapping" and a crime. The speakers warn that this behavior exposes the US to a "bear trap" set by Russia and China, who can inflict damage without direct escalation. Contrasting Putin's calculated "restraint" and "legalism" with Trump's "bull in a china shop" approach, they suggest the US is rapidly losing international authority. Consequently, the crisis may force a "quid pro quo," where the US might have to trade influence in Ukraine to resolve the situation in the Western Hemisphere, effectively accepting a bargain to escape the "brier patch." NUMBER 2 1953

Dr. DebWhat if I told you that the stomach acid medication you’re taking for heartburn is actually causing the problem it’s supposed to solve that your doctor learned virtually nothing about nutrition, despite spending 8 years in medical school. That the very system claiming to heal you was deliberately designed over a hundred years ago by an oil tycoon, John D. Rockefeller, to create lifelong customers, not healthy people. Last week a patient spent thousands of dollars on tests and treatments for acid reflux, only to discover she needed more stomach acid, not less. The medication keeping her sick was designed to do exactly that. Today we’re exposing the greatest medical deception in modern history, how a petroleum empire systematically destroyed natural healing wisdom turned medicine into a profit machine. And why the treatments, keeping millions sick were engineered that way from the beginning. This isn’t about conspiracy theories. This is a documented history that explains why you feel so lost about your own body’s needs welcome back to let’s talk wellness. Now the show where we uncover the root causes of chronic illness, explore cutting edge regenerative medicine, and empower you with the tools to heal. I’m Dr. Deb. And today we’re diving into how the Rockefeller Medical Empire systematically destroyed natural healing wisdom and replaced it with profit driven systems that keeps you dependent on treatments instead of achieving true health. If you or someone you love has been running to the doctor for every minor ailment, taking acid blockers that seem to make digestive problems worse, or feeling confused about basic body functions that our ancestors understood instinctively. This episode is for you. So, as usual, grab a cup of coffee, tea, or whatever helps you unwind. Settle in and let’s get started on your journey to reclaiming your health sovereignty all right. So here we are talking about the Rockefeller Medical Revolution. Now, what if your symptoms aren’t true diagnosis, but rather the predictable result of a medical system designed over a hundred years ago to create lifelong customers instead of healthy people. Now I learned this when I was in naturopathic school over 20 years ago. And it hasn’t been talked about a lot until recently. Recently. People are exposing the truth about what actually happened in our medical system. And today I want to take you back to the early 19 hundreds to understand how we lost the basic health wisdom that sustained humanity for thousands of years. Yes, I said that thousands of years. This isn’t conspiracy theory. This is documented history. That explains why you feel so lost when it comes to your own body’s needs. You know by the turn of the 20th century. According to meridian health Clinic’s documentation. Rockefeller controlled 90% of all petroleum refineries in America and through ownership of the Standard Oil Corporation. But Rockefeller saw an opportunity that went far beyond oil. He recognized that petrochemicals could be the foundation for a completely new medical system. And here’s what most people don’t know. Natural and herbal medicines were very popular in America during the early 19 hundreds. According to Staywell, Copper’s historical analysis, almost one half of medical colleges and doctors in America were practicing holistic medicine, using extensive knowledge from Europe and native American traditions. People understood that food was medicine, that the body had natural healing mechanisms, and that supporting these mechanisms was the key to health. But there was a problem with the Rockefeller’s business plan. Natural medicines couldn’t be patented. They couldn’t make a lot of money off of them, because they couldn’t hold a patent. Petrochemicals, however, could be patented, could be owned, and could be sold for high profits. So Rockefeller and Andrew Carnegie devised a systematic plan to eliminate natural medicine and replace it with petrochemical based pharmaceuticals and according to E. Richard Brown’s comprehensive academic documentation in Rockefeller, medicine men. Medicine, and capitalism in America. They employed the services of Abraham Flexner, who proceeded to visit and assess every single medical school in us and in Canada. Within a very short time of this development, medical schools all around the us began to collapse or consolidate. The numbers are staggering. By 1910 30 schools had merged, and 21 had closed their doors of the 166 medical colleges operating in 19 0, 4, a hundred 33 had survived by 1910 and a hundred 4 by 1915, 15 years later, only 76 schools of medicine existed in the Us. And they all followed the same curriculum. This wasn’t just about changing medical education. According to Staywell’s copper historical analysis. Rockefeller and Carnegie influenced insurance companies to stop covering holistic treatments. Medical professionals were trained in the new pharmaceutical model and natural solutions became outdated or forgotten. Not only that alternative healthcare practitioners who wanted to stay practicing in alternative medicine were imprisoned for doing so as documented by the potency number 710. The goal was clear, create a system where scientists would study how plants cure disease, identify which chemicals in the plants were effective and then recreate a similar but not identical chemical in the laboratory that would be patented. E. Richard Brown’s documents. The story of how a powerful professional elite gained virtual homogeny in the western theater of healing by effectively taking control of the ethos and practice of Western medicine. The result, according to the healthcare spending data, the United States now spends 17.6% of its Gdp on health care 4.9 trillion dollars in 2023, or 14,570 per person nearly twice as much as the average Oecd country. But it doesn’t focus on cure. But on symptoms, and thus creating recurring clients. This systematic destruction of natural medicine explains why today’s healthcare providers often seem baffled by simple questions about nutrition why they immediately reach for a prescription medication for minor ailments, and why so many people feel disconnected from their own body’s wisdom. We’ve been trained over 4 generations to believe that our bodies are broken, and that symptoms are diseases rather than messages, and that external interventions are always superior to supporting natural healing processes. But here’s what they couldn’t eliminate your body’s innate wisdom. Your digestive system still functions the same way it did a hundred years ago. Your immune system still follows the same patterns. The principles of nutrition, movement and stress management haven’t changed. We’ve just forgotten how to listen and respond. We’re gonna take a small break here and hear from our sponsor. When we come back. We’re gonna talk about the acid reflux deception, and why your cure is making you sicker, so don’t go away all right, welcome back. So I want to give you a perfect example of how Rockefeller medicine has turned natural body wisdom upside down, the treatment of acid, reflux, and heartburn. Every single day in my practice I see patients who’ve been taking acid blocker medications, proton pump inhibitors like prilosec nexium or prevacid for years, not for weeks, years, and sometimes even decades. They come to me because their digestive problems are getting worse, not better. They have bloating and gas and nutrition deficiencies. And we’re seeing many more increased food sensitivities. And here’s what’s happening in the Us. Most people often attribute their digestive problems to too much stomach acid. And they use medications to suppress the stomach acid, but, in fact symptoms of chronic acid, reflux, heartburn, or gerd, can also be caused by too little stomach acid, a condition called hyper. Sorry hypochlorhydria normal stomach acid has a Ph level of one to 2, which is highly acidic. Hydrochloric acid plays an important role in your digestion and your immunity. It helps to break down proteins and absorb essential nutrients, and it helps control viruses and bacteria that might otherwise infect your stomach. But here’s the crucial part that most people don’t understand, and, according to Cleveland clinic, your stomach secretes lower amounts of hydrochloric acid. As you age. Hypochlorhydria is more common in people over the age of 40, and even more common over the age of 65. Webmd states that the stomach acid can produce less acid as a result of aging and being 65 or older is a risk factor for developing hypochlorhydria. We’ve been treating this in my practice for a long time. It’s 1 of the main foundations that we learn as naturopathic practitioners and as naturopathic doctors, and there are times where people need these medications, but they were designed to be used short term not long term in a 2,013 review published in Medical News today, they found that hypochlorhydria is the main change in the stomach acid of older adults. and when you have hypochlorydria, poor digestion from the lack of stomach, acid can create gas bubbles that rise into your esophagus or throat, carrying stomach acid with them. You experience heartburn and assume that you have too much acid. So you take acid blockers which makes the underlying problem worse. Now, here’s something that will shock you. PPI’s protein pump inhibitors were originally studied and approved by the FDA for short-term use only according to research published in us pharmacists, most cases of peptic ulcers resolve in 6 to 8 weeks with PPI therapy, which is what these medications were created for. Originally the American family physician reports that for erosive esophagitis. Omeprazole is indicated for short term 4 to 8 weeks. That’s it. Treatment and healing and done if needed. An additional 4 to 8 weeks of therapy may be considered and the University of Minnesota College of Pharmacy, States. Guidelines recommended a treatment duration of 8 weeks with standard once a day dosing for a PPI for Gerd. The Canadian family physician, published guidelines where a team of healthcare professionals recommended prescribing Ppis in adults who suffer from heartburn and who have completed a minimum treatment of 4 weeks in which symptoms were relieved. Yet people are taking these medications for years, even decades far beyond their intended duration of use and a study published in Pmc. Found that the threshold for defining long-term PPI use varied from 2 weeks to 7 years of PPI use. But the most common definition was greater than one year or 6 months, according to the research in clinical context, use of Ppis for more than 8 weeks could be reasonably defined as long-term use. Now let’s talk about what these acid blocker medications are actually doing to your body when used. Long term. The research on long term PPI use is absolutely alarming. According to the comprehensive review published in pubmed central Pmc. Long-term use of ppis have been associated with serious adverse effects, including kidney disease, cardiovascular disease fractures because you’re not absorbing your nutrients, and you’re being depleted. Infections, including C. Diff pneumonia, micronutrient deficiencies and hypomagnesium a low level of magnesium anemia, vitamin, b, deficiency, hypocalcemia, low calcium, low potassium. and even cancers, including gastric cancer, pancreatic cancer, colorectal cancer. And hepatic cancer and we are seeing all of these cancers on a rise, and we are now linking them back to some of these medications. Mayo clinic proceedings published research showing that recent studies regarding long-term use of PPI medication have noted potential adverse effects, including risks of fracture, pneumonia, C diff, which is a diarrhea. It’s a bacteria, low magnesium, low b 12 chronic kidney disease and even dementia. And a 2024 study published in nature communications, analyzing over 2 million participants from 5 cohorts found that PPI use correlated with increased risk of 15 leading global diseases, such as ischemic heart disease. Diabetes, respiratory infections, chronic kidney disease. And these associations showed dose response relationships and consistency across different PPI types. Now think about this. You take a medication for heartburn that was designed for 4 to 8 weeks of use, and when used long term, it actually increases your risk of life, threatening infections, kidney disease, and dementia. This is the predictable result of suppressing a natural body function that exists for important reasons. Hci plays a key role in many physiological processes. It triggers, intestinal hormones, prepares folate and B 12 for absorption, and it’s essential for absorption of minerals, including calcium, magnesium, potassium, zinc, and iron. And when you block acid production, you create a cascade of nutritional deficiencies and immune system problems that often manifest as seemingly unrelated health issues. So what’s the natural approach? Instead of suppressing stomach acid, we need to support healthy acid production and address the root cause of reflux healthcare. Providers may prescribe hcl supplements like betaine, hydrochloric acid. Bhcl is what it’s called. Sometimes it’s called betaine it’s often combined with enzymes like pepsin or amylase or lipase, and it’s used to treat hydrochloric acid deficiency, hypochlorhydria. These supplements can help your digestion and sometimes help your stomach acid gradually return back to normal levels where you may not need to use them all the time. Simple strategies include consuming protein at the beginning of the meal to stimulate Hcl production, consume fluids separately at least 30 min away from meals, if you can, and address the underlying cause like chronic stress and H. Pylori infections. This is such a sore subject for me. So many people walk around with an H. Pylori infection. It’s a bacterial infection in the stomach that can cause stomach ulcers, causes a lot of stomach pain and burning. and nobody is treating the infection. It’s a bacterial infection. We don’t treat this anymore with antibiotics or antimicrobials. We treat it with Ppis. But, Ppis don’t fix the problem. You have to get rid of the bacteria once the bacteria is gone, the gut lining can heal. Now it is a common bacteria. It can reoccur quite frequently. It’s highly contagious, so you can pick it up from other people, and it may need multiple courses of treatment over a person’s lifetime. But you’re actually treating the problem. You’re getting rid of the bacteria that’s creating the issue instead of suppressing the acid. That’s not fixing the bacteria which then leads to a whole host of other problems that we just talked about. There are natural approaches to increase stomach acid, including addressing zinc deficiency. And since the stomach uses zinc to produce Hcl. Taking probiotics to help support healthy gut bacteria and using digestive bitters before meals can be really helpful. This is exactly what I mean about reclaiming the body’s wisdom. Instead of suppressing natural functions, we support them instead of creating drug dependency, we restore normal physiology. Instead of treating symptoms indefinitely, we address the root cause and help the body heal itself. In many cultures. Bitters is a common thing to use before or after a meal. But yet in the American culture we don’t do that anymore. We’ve not passed on that tradition. So very few people understand how to use bitters, or what bitters are, or why they’re important. And these basic things that can be used in your food and cooking and taking could replace thousands of dollars of medication that you don’t really need. That can create many more problems along the way. Now, why does your doctor know nothing about nutrition. Well, I want to address something that might shock you all. The reason your doctor seems baffled when you ask about nutrition isn’t because they’re not intelligent. It’s because they literally never learned this in medical school statistics on nutritional education in medical schools are staggering and help explain why we have such a health literacy crisis in America. According to recent research published in multiple academic journals, only 27% of Us. Medical schools actually offer students. The recommended 25 h of nutritional training across 4 years of medical school. That means 73% of the medical schools don’t even meet the minimum standards set in 1985. But wait, it gets worse. A 2021 survey of medical schools in the Us. And the Uk. Found that most students receive an average of only 11 h of nutritional training throughout their entire medical program. and another recent study showed that in 2023 a survey of more than a thousand Us. Medical students. About 58% of these respondents said they received no formal nutritional education while in medical school. For 4 years those who did averaged only 3 h. I’m going to say this again because it’s it’s huge 3 h of nutritional education per year. So let me put this in perspective during 4 years of medical school most students spend fewer than 20 h on nutrition that’s completely disproportionate to its health benefits for patients to compare. They’ll spend hundreds of hours learning about pharmaceutical interventions, but virtually no time learning how food affects health and disease. Now, could this be? Why, when we talk about nutrition to lower cholesterol levels or control your diabetes, they blow you off, and they don’t answer you. It’s because they don’t understand. But yet what they’ll say is, people won’t change their diet. That’s why you have to take medication. That’s not true. I will tell you. I work with people every single day who are willing to change their diet. They’re just confused by all the information that’s out there today about nutrition. And what diet is the right diet to follow? Do I do, Paleo? Do I do? Aip? Do I do carnivore? Do I do, Keto? Do I do? Low carb? There’s so many diets out there today? It’s confusing people. So I digress. But let’s go back. So here’s the kicker. The limited time medical students do spend on nutrition office often focuses on nutrients think proteins and carbohydrates rather than training in topics such as motivational interviewing or meal planning, and as one Stanford researcher noted, we physicians often sound like chemists rather than counselors who can speak with patients about diet. Isn’t that true? We can speak super high level up here, but we can’t talk basics about nutrition. And this explains why only 14% of the physicians believe they were adequately trained in nutritional counseling. Once they entered practice and without foundational concepts of nutrition in undergrad work. Graduate medical education unsurprisingly falls short of meeting patients, needs for nutritional guidance in clinical practice, and meanwhile diet, sensitive chronic diseases continue to escalate. Although they are largely preventable and treatable by nutritional therapies and dietary. Lifestyle changes. Now think about this. Diet. Related diseases are the number one cause of death in the Us. The number one cause. Yet many doctors receive little to no nutritional education in medical school, and according to current health statistics from 2017 to march of 2020. Obesity prevalence was 19.7% among us children and adolescents affecting approximately 14.7 million young people. About 352,000 Americans, under the age of 20, have been diagnosed with diabetes. Let me say this again, because these numbers are astounding to me. 352,000 Americans, under the age of 20, have been diagnosed with diabetes with 5,300 youth diagnosed with type, 2 diabetes annually. Yet the very professionals we turn to for health. Guidance were never taught how food affects these conditions and what drug has come to the rescue Glp. One S. Ozempic wegovy. They’re great for weight loss. They’re great for treating diabetes. But why are they here? Well, these numbers are. Why, they’re here. This is staggering to put 352,000 Americans under the age of 20 on a glp, one that they’re going to be on for the rest of their lives at a minimum of $1,200 per month. All we have to do is do the math, you guys, and we can see exactly what’s happening to our country, and who is getting rich, and who is getting the short end of the stick. You’ve become a moneymaker to the pharmaceutical industry because nobody has taught you how to eat properly, how to live, how to have a healthy lifestyle, and how to prevent disease, or how to actually reverse type 2 diabetes, because it’s reversible in many cases, especially young people. And we do none of that. All we do is prescribe medications. Metformin. Glp, one for the rest of your life from 20 years old to 75, or 80, you’re going to be taking medications that are making the pharmaceutical companies more wealth and creating a disease on top of a disease on top of a disease. These deficiencies in nutritional education happen at all levels of medical training, and there’s been little improvement, despite decades of calls for reform. In 1985, the National Academy of Sciences report that they recommended at least 25 h of nutritional education in medical school. But a 2015 study showed only 29% of medical schools met this goal, and a 2023 study suggests the problem has become even worse. Only 7.8% of medical students reported 20 or more hours of nutritional education across all 4 years of medical school. This systemic lack of nutrition, nutritional education has been attributed to several factors a dearth of qualified instructors for nutritional courses, since most physicians do not understand nutrition well enough to teach it competition for curriculum time, with schools focusing on pharmaceutical interventions rather than lifestyle medicine and a lack of external incentives that support schools, teaching nutrition. And ironically, many medical schools are part of universities that have nutrition departments with Phd. Trained professors who could fill this gap by teaching nutrition in medical schools but those classes are often taught by physicians who may not have adequate nutritional training themselves. This explains so much about what I see in my practice. Patients come to me confused and frustrated because their primary care doctors can’t answer basic questions about how food affects their health conditions. And these doctors aren’t incompetent. They simply were never taught this information. And the result is that these physicians graduate, knowing how to prescribe medications for diabetes, but not how dietary changes can prevent or reverse it. They can treat high blood pressure with pharmaceuticals, but they may not know that specific nutritional approaches can be equally or more effective. This isn’t the doctor’s fault. It’s the predictable result of medical education systems that was deliberately designed to focus on patentable treatments rather than natural healing approaches. And remember this traces back to the Rockefeller influence on medical education. You can’t patent an apple or a vegetable. But you can patent a drug now. Why can’t we trust most medical studies? Well this just gets even better. I need to address something that’s crucial for you to understand as you navigate health information. Why so much of the medical research you hear about in the news is biased, and why peer Review isn’t the gold standard of truth you’ve been told it is. The corruption in medical research by pharmaceutical companies is not a conspiracy theory. It’s well documented scientific fact, according to research, published in frontiers, in research, metrics and analytics. When pharmaceutical and other companies sponsor research, there is a bias. A systematic tendency towards results serving their interests. But the bias is not seen in the formal factors routinely associated with low quality science. A Cochrane Review analyzed 75 studies of the association between industry, funding, and trial results, and these authors concluded that trials funded by a drug or device company were more likely to have positive conclusions and statistically significant results, and that this association could not be explained by differences in risk of bias between industry and non-industry funded trials. So think about that. According to the Cochrane collaboration, industry funding itself should be considered a standard risk of bias, a factor in clinical trials. Studies published in science and engineering ethics show that industry supported research is much more likely to yield positive outcomes than research with any other sponsorship. And here’s how the bias gets introduced through choice of compartor agents, multiple publications of positive trials and non-publication of negative trials reinterpreting data submitted to regulatory agencies, discordance between results and conclusions, conflict of interest leading to more positive conclusions, ghostwriting and the use of seating trials. Research, published in the American Journal of Medicine. Found that a result favorable to drug study was reported by all industry, supported studies compared with two-thirds of studies, not industry, supported all industry, supported studies showed favorable results. That’s not science that’s marketing, masquerading as research. And according to research, published in sciencedirect the peer review system which we’re told ensures quality. Science has a major limitation. It has proved to be unable to deal with conflicts of interest, especially in big science contexts where prestigious scientists may have similar biases and conflicts of interest are widely shared among peer reviewers. Even government funded research can have conflicts of interest. Research published in pubmed States that there are significant benefits to authors and investigators in participating in government funded research and to journals in publishing it, which creates potentially biased information that are rarely acknowledged. And, according to research, published in frontiers in research, metrics, and analytics, the pharmaceutical industry has essentially co-opted medical knowledge systems for their particular interests. Using its very substantial resources. Pharmaceutical companies take their own research and smoothly integrate it into medical science. Taking advantage of the legitimacy of medical institutions. And this corruption means that much of what passes for medical science is actually influenced by commercial interests rather than pursuant of truth. Research published in Pmc. Shows that industry funding affects the results of clinical trials in predictable directions, serving the interests of the funders rather than the patients. So where can we get this reliable, unbiased Health information, because this is critically important, because your health decisions should be based on the best available evidence, not marketing disguised as science. And so here are some sources that I recommend for trustworthy health and nutritional information. They’re independent academic sources. According to Harvard Chan School of public health their nutritional, sourced, implicitly states their content is free from industry, influence, or support. The Linus Pauling Institute, Micronutrient Information Center at Oregon State University, which, according to the Glendale Community college Research Guide provides scientifically accurate information about vitamins, minerals, and other dietary factors. This Institute has been around for decades. I’ve used it a lot. I’ve gotten a lot of great information from them. Very, very trustworthy. According to the Glendale Community College of Nutrition Resource guide Tufts, University of Human Nutritional Research Center on aging is one of 6 human nutrition research centers supported by the United States Department of Agriculture, the Usda. Their peer reviewed journals with strong editorial independence though you must still check funding resources. And how do you evaluate this information? Online? Well, according to medlineplus and various health literacy guides when evaluating health information medical schools and large professional or nonprofit organizations are generally reliable sources, but remember, it is tainted by the Rockefeller method. So, for example, the American College of cardiology. Excuse me. Professional organization and the American Heart Institute a nonprofit are both reliable sources. Sorry about that of information on heart health and watch out for ads designed to look like neutral health information. If the site is funded by ads they should be clearly marked as advertisements. Excuse me, I guess I’m talking just a little too much now. So when the fear of medicine becomes deadly. Now, I want to address something critically important that often gets lost in conversations about health, sovereignty, and questioning the medical establishment. And while I’ve spent most of this episode explaining how the Rockefeller medical system has created dependency and suppressed natural healing wisdom. There’s a dangerous pendulum swing happening that I see in my practice. People becoming so fearful of pharmaceutical interventions that they refuse lifesaving treatments when they’re genuinely needed. This is where balance and clinical judgment become absolutely essential. Yes, we need to reclaim our basic health literacy and reduce our dependency on unnecessary medical interventions. But there are serious bacterial infections that require immediate antibiotic treatment, and the consequences of avoiding treatment can be devastating or even fatal. So let me share some examples from research that illustrate when antibiotic fear becomes dangerous. Let’s talk about Lyme disease, and when natural approaches might not be enough. The International Lyme Disease Association ilads has conducted extensive research on chronic lyme disease, and their findings are sobering. Ileds defines chronic lyme disease as a multi-system illness that results from an active and ongoing infection of pathogenic members of the Borrelia Brdorferi complex. And, according to ilads research published in their treatment guidelines, the consequences of untreated persistent lyme infection far outweigh the potential consequences of long-term antibiotic therapy in well-designed trials of antibiotic retreatment in patients with severe fatigue, 64% in the treatment arm obtained clinically significant and sustained benefit from additional antibiotic therapy. Ilas emphasizes that cases of chronic borrelia require individualized treatment plans, and when necessary antibiotic therapy should be extended their research demonstrates that 20 days of prophylactic antibiotic treatment may be highly effective for preventing the onset of lyme disease. After known tick bites and patients with early Lyme disease may be best served by receiving 4 to 6 weeks of antibiotic therapy. Research published in Pmc. Shows that patients with untreated infections may go on to develop chronic, debilitating, multisystem illnesses that is difficult to manage, and numerous studies have documented persistent Borrelia, burgdorferi infection in patients with persistent symptoms of neurological lyme disease following short course. Antibiotic treatment and animal models have demonstrated that short course. Antibiotic therapy may fail to eradicate lyme spirochetes short course is a 1 day. One pill treatment of doxycycline. Or less than 20 days of antibiotics, is considered a short course. It’s not long enough to kill the bacteria. The bacteria’s life cycle is about 21 days, so if you don’t treat the infection long enough, the likelihood of that infection returning is significant. They’ve also done studies in the petri dish, where they show doxycycline being put into a petri dish with active lyme and doxycycline does not kill the infection, it just slows the replication of it. Therefore, using only doxycycline, which is common practice in lyme disease may not completely eradicate that infection for you. So let’s talk about another life threatening emergency. C. Diff clostridia difficile infection, which represents another example where antibiotic treatment is absolutely essential, despite the fact that C diff itself is often triggered by antibiotic use. According to Cleveland clinic C. Diff is estimated to cause almost half a million infections in the United States each year, with 500,000 infections, causing 15,000 deaths each year. Studies reported by Pmc. Found thirty-day Cdi. Mortality rates ranging from 6 to 11% and hospitalized Cdi patients have significantly increased the risk of mortality and complications. Research published in Pmc shows that 16.5% of Cdi patients experience sepsis and that this increases with reoccurrences 27.3% of patients with their 1st reoccurrence experience sepsis. While 33.1% with 2 reoccurrences and 43.2% with 3 or more reoccurrences. Mortality associated with sepsis is very high within hospital 30 days and 12 month mortality rates of 24%, 30% and 58% respectively. According to the Cdc treatment for C diff infection usually involves taking a specific antibiotic, such as vancomycin for at least 10 days, and while this seems counterintuitive, treating an antibiotic associated infection with more antibiotics. It’s often lifesaving. Now let’s talk about preventing devastating complications. Strep throat infections. Provide perhaps the clearest example of when antibiotic treatment prevents serious long-term consequences, and, according to Mayo clinic, if untreated strep throat can cause complications such as kidney inflammation and rheumatic fever. Rheumatic fever can lead to painful and inflamed joints, and a specific type of rash of heart valve damage. We also know that strep can cause pans pandas, which is a systemic infection, often causing problems with severe Ocd. And anxiety and affecting mostly young people. The research is unambiguous. According to the Cleveland clinic. Rheumatic fever is a rare complication of untreated strep, throat, or scarlet fever that most commonly affects children and teens, and in severe cases it can lead to serious health problems that can affect your child’s heart. Joints and organs. And research also shows that the rate of development of rheumatic fever in individuals with untreated strep infections is estimated to be 3%. The incidence of reoccurrence with a subsequent untreated infection is substantially greater. About 50% the rate of development is far lower in individuals who have received antibiotic treatment. And according to the World health organization, rheumatic heart disease results from the inflammation and scarring of the heart valves caused by rheumatic fever, and if rheumatic fever is not treated promptly, rheumatic heart disease may occur, and rheumatic heart disease weakens the valves between the chambers of the heart, and severe rheumatic heart disease can require heart surgery and result in death. The who states that rheumatic heart disease remains the leading cause of maternal cardiac complications during pregnancy. And additionally, according to the National Kidney foundation. After your child has either had throat or skin strep infection, they can develop post strep glomerial nephritis. The Strep bacteria travels to the kidneys and makes the filtering units of the kidneys inflamed, causing the kidneys to be able to unable or less able to fill and filter urine. This can develop one to 2 weeks after an untreated throat infection, or 3 to 4 weeks after an untreated skin infection. We need to find balance. And here’s what I want you to understand. Questioning the medical establishment and developing health literacy doesn’t mean rejecting all medical interventions. It means developing the wisdom to know when they’re necessary and lifesaving versus when they’re unnecessary and potentially harmful. When I see patients with confirmed lyme disease, serious strep infections or life. Threatening conditions like C diff. I don’t hesitate to recommend appropriate therapy but I also work to support their overall health address, root causes, protect and restore their gut microbiome and help them recover their natural resilience. The goal isn’t to avoid all medical interventions. It’s to use them wisely when truly needed, while simultaneously supporting your body’s inherent healing capacity and addressing the lifestyle factors that created the vulnerability. In the 1st place. All of this can be extremely overwhelming, and it can be frightening to understand or learn. But remember, the power that you have is knowledge. The more you learn about what’s actually happening in your health, in understanding nutrition. in learning what your body wants to be fed, and how it feels, and working with practitioners who are holistic in nature, natural, integrative, functional, whatever we want to call that these days. The more you can learn from them, the more control you have over your own health and what I would urge you to do is to teach your children what you’re learning. Teach them how to live a healthy lifestyle, teach them how to keep a clean environment. This is how we take back our own health. So thank you for joining me today on, let’s talk wellness. Now, if this episode resonated with you. Please share it with someone who could benefit from understanding how the Rockefeller medical system has shaped our approach to health, and how to reclaim your body’s wisdom while using medical care appropriately when truly needed. Remember, wellness isn’t just about feeling good. It’s about understanding your body, trusting its wisdom, supporting its natural healing capacity, and knowing when to seek appropriate medical intervention. If you’re ready to explore how functional medicine can help you develop this deeper health knowledge while addressing root causes rather than just managing symptoms. You can get more information from serenityhealthcarecenter.com, or reach out directly to us through our social media channels until next time. I’m Dr. Dab, reminding you that your body is your wisest teacher. Learn to listen, trust the process, use medical care wisely when needed, and take care of your body, mind, and spirit. Be well, and we’ll see you on the next episode.The post Episode 250 -The Great Medical Deception first appeared on Let's Talk Wellness Now.

Episode 210: Heat Stroke BasicsWritten by Jacob Dunn, MS4, American University of the Caribbean. Edits and comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice. Definition:Heat stroke represents the most severe form of heat-related illness, characterized by a core body temperature exceeding 40°C (104°F) accompanied by central nervous system (CNS) dysfunction. Arreaza: Key element is the body temperature and altered mental status. Jacob: This life-threatening condition arises from the body's failure to dissipate heat effectively, often in the context of excessive environmental heat load or strenuous physical activity. Arreaza: You mentioned, it is a spectrum. What is the difference between heat exhaustion and heat stroke? Jacob: Unlike milder heat illnesses such as heat exhaustion, heat stroke involves multisystem organ dysfunction driven by direct thermal injury, systemic inflammation, and cytokine release. You can think of it as the body's thermostat breaking under extreme stress — leading to rapid, cascading failures if not addressed immediately. Arreaza: Tell us what you found out about the pathophysiology of heat stroke?Jacob: Pathophysiology: Under normal conditions, the body keeps its core temperature tightly controlled through sweating, vasodilation of skin blood vessels, and behavioral responses like seeking shade or drinking water. But in extreme heat or prolonged exertion, those mechanisms get overwhelmed.Once core temperature rises above about 40°C (104°F), the hypothalamus—the brain's thermostat—can't keep up. The body shifts from controlled thermoregulation to uncontrolled, passive heating. Heat stroke isn't just someone getting too hot—it's a full-blown failure of the body's heat-regulating system. Arreaza: So, it's interesting. the cell functions get affected at this point, several dangerous processes start happening at the same time.Jacob: Yes: Cellular Heat InjuryHigh temperatures disrupt proteins, enzymes, and cell membranes. Mitochondria start to fail, ATP production drops, and cells become leaky. This leads to direct tissue injury in vital organs like the brain, liver, kidneys, and heart.Arreaza: Yikes. Cytokines play a big role in the pathophysiology of heat stroke too. Jacob: Systemic Inflammatory ResponseHeat damages the gut barrier, allowing endotoxins to enter the bloodstream. This triggers a massive cytokine release—similar to sepsis. The result is widespread inflammation, endothelial injury, and microvascular collapse.Arreaza: What other systems are affected?Coagulation AbnormalitiesEndothelial damage activates the clotting cascade. Patients may develop a DIC-like picture: microthrombi forming in some areas while clotting factors get consumed in others. This contributes to organ dysfunction and bleeding.Circulatory CollapseAs the body shunts blood to the skin for cooling, perfusion to vital organs drops. Combine that with dehydration from sweating and fluid loss, and you get hypotension, decreased cardiac output, and worsening ischemia.Arreaza: And one of the key features is neurologic dysfunction.Jacob: Neurologic DysfunctionThe brain is extremely sensitive to heat. Encephalopathy, confusion, seizures, and coma occur because neurons malfunction at high temperatures. This is why altered mental status is the hallmark of true heat stroke.Arreaza: Cell injury, inflammation, coagulopathy, circulatory collapse and neurologic dysfunction. Jacob: Ultimately, heat stroke is a multisystem catastrophic event—a combination of thermal injury, inflammatory storm, coagulopathy, and circulatory collapse. Without rapid cooling and aggressive supportive care, these processes spiral into irreversible organ failure.Background and Types:Arreaza: Heat stroke is part of a spectrum of heat-related disorders—it is a true medical emergency. Mortality rate reaches 30%, even with optimal treatment. This mortality correlates directly with the duration of core hyperthermia. I'm reminded of the first time I heard about heat stroke in a baby who was left inside a car in the summer 2005. Jacob: There are two primary types: -nonexertional (classic) heat stroke, which develops insidiously over days and predominantly affects vulnerable populations like children, the elderly, and those with chronic illnesses during heat waves; -exertional heat stroke, which strikes rapidly in young, otherwise healthy individuals, often during intense exercise in hot, humid conditions. Arreaza: In our community, farm workers are especially at risk of heat stroke, but any person living in the Central Valley is basically at risk.Jacob: Risk factors amplify vulnerability across both types, including dehydration, cardiovascular disease, medications that impair sweating (e.g., anticholinergics), and acclimatization deficits. Notably, anhidrosis (lack of sweating) is common but not required for diagnosis. Hot, dry skin can signal the shift from heat exhaustion to stroke. Arreaza: What other conditions look like heat stroke?Differential Diagnosis:Jacob: Presenting with altered mental status and hyperthermia, heat stroke demands a broad differential to avoid missing mimics. -Environmental: heat exhaustion, syncope, or cramps. -Infectious etiologies like sepsis or meningitis must be ruled out. -Endocrine emergencies such as thyroid storm, pheochromocytoma, or diabetic ketoacidosis (DKA) can overlap. -Neurologic insults include cerebrovascular accident (CVA), hypothalamic lesions (bleeding or infarct), or status epilepticus. -Toxicologic culprits are plentiful—sympathomimetic or anticholinergic toxidromes, salicylate poisoning, serotonin syndrome, malignant hyperthermia, neuroleptic malignant syndrome (NMS), or even alcohol/benzodiazepine withdrawal. When it comes to differentials, it is always best to cast a wide net and think about what we could be missing if this is not heat stroke. Arreaza: Let's say we have a patient with hyperthermia and we have to assess him in the ER. What should we do to diagnose it?Jacob: Workup:Diagnosis is primarily clinical, hinging on documented hyperthermia (>40°C) plus CNS changes (e.g., confusion, delirium, seizures, coma) in a hot environment. Arreaza: No single lab confirms it, but targeted testing allows us to detect complications and rule out alternative diagnosis. Jacob: -Start with ECG to assess for dysrhythmias or ischemic changes (sinus tachycardia is classic; ST depressions or T-wave inversions may hint at myocardial strain). -Labs include complete blood count (CBC), comprehensive metabolic panel (electrolytes, renal function, liver enzymes), glucose, arterial blood gas, lactate (elevated in shock), coagulation studies (for disseminated intravascular coagulation, or DIC), creatine kinase (CK) and myoglobin (for rhabdomyolysis), and urinalysis. Toxicology screen if history suggests. Arreaza: I can imagine doing all this while trying to cool down the patient. What about imaging?-Imaging: chest X-ray for pulmonary issues, non-contrast head CT if neurologic concerns suggest edema or bleed (consider lumbar puncture if infection suspected). It is important to note that continuous core temperature monitoring—via rectal, esophageal, or bladder probe—is essential, not just peripheral skin checks. Arreaza: TreatmentManagement:Time is tissue here—initiate cooling en route, if possible, as delays skyrocket morbidity. ABCs first: secure airway (intubate if needed, favoring rocuronium over succinylcholine to avoid hyperkalemia risk), support breathing, and stabilize circulation. -Remove the patient from the heat source, strip clothing, and launch aggressive cooling to target 38-39°C (102-102°F) before halting to prevent rebound hypothermia. -For exertional cases, ice-water immersion reigns supreme—it's the fastest method, with immersion in cold water resulting in near-100% survival if started within 30 minutes. -Nonexertional benefits from evaporative cooling: mist with tepid water (15-25°C) plus fans for convective airflow. -Adjuncts include ice packs to neck, axillae, and groin; -room-temperature IV fluids (avoid cold initially to prevent shivering); -refractory cases, invasive options like peritoneal lavage, endovascular cooling catheters, or even ECMO. -Fluid resuscitation with lactated Ringer's or normal saline (250-500 mL boluses) protects kidneys and counters rhabdomyolysis—aim for urine output of 2-3 mL/kg/hour. Arreaza: What about medications?Jacob: Benzodiazepines (e.g., lorazepam) control agitation, seizures, or shivering; propofol or fentanyl if intubated. Avoid antipyretics like acetaminophen. For intubation, etomidate or ketamine as induction agents. Hypotension often resolves with cooling and fluids; if not, use dopamine or dobutamine over norepinephrine to avoid vasoconstriction. Jacob: What IV fluid is recommended/best for patients with heat stroke?Both lactated Ringer's solution and normal saline are recommended as initial IV fluids for rehydration, but balanced crystalloids such as LR are increasingly favored due to their lower risk of hyperchloremic metabolic acidosis and AKI. However, direct evidence comparing the two specifically in the setting of heat stroke is limited. Arreaza: Are cold IV fluids better/preferred over room temperature fluids?Cold IV fluids are recommended as an adjunctive therapy to help lower core temperature in heat stroke, but they should not delay or replace primary cooling methods such as cold-water immersion. Cold IV fluids can decrease core temperature more rapidly than room temperature fluids. For example, 30mL/kg bolus of chilled isotonic fluids at 4 degrees Celsius over 30 minutes can decrease core temperature by about 1 degree Celsius, compared to 0.5 degree Celsius with room temperature fluids. Arreaza: Getting cold IV sounds uncomfortable but necessary for those patients. Our favorite topic.Screening and Prevention:-Heat stroke prevention focuses on public health and individual awareness rather than routine testing. -High-risk groups—elderly, children, athletes, laborers, or those on impairing meds—should acclimatize gradually (7-14 days), hydrate preemptively (electrolyte solutions over plain water), and monitor temperature in exertional settings. -Communities during heat waves need cooling centers and alerts. -For clinicians, educate patients with CVD or obesity about early signs like dizziness or nausea. -No formal "screening" exists, but vigilance in EDs during summer surges saves lives. -Arreaza: I think awareness is a key element in prevention, so education of the public through traditional media like TV, and even social media can contribute to the prevention of this catastrophic condition.Jacob: Ya so heat stroke is something that should be on every physician's radar in the central valley especially in the summer time given the hot temperatures. Rapid recognition is key. Arreaza: Thanks, Jacob for this topic, and until next time, this is Dr. Arreaza, signing off.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! References:Gaudio FG, Grissom CK. Cooling Methods in Heat Stroke. J Emerg Med. 2016 Apr;50(4):607-16. doi: 10.1016/j.jemermed.2015.09.014. Epub 2015 Oct 31. PMID: 26525947. https://pubmed.ncbi.nlm.nih.gov/26525947/.Platt, M. A., & LoVecchio, F. (n.d.). Nonexertional classic heat stroke in adults. In UpToDate. Retrieved September 7, 2025, from https://www.uptodate.com/contents/nonexertional-classic-heat-stroke-in-adults. (Key addition: Emphasizes insidious onset in at-risk populations and the role of urban heat islands in exacerbating classic cases.) Heat Stroke. WikEM. Retrieved December 3, 2025, from https://wikem.org/wiki/Heat_stroke. (Key additions: Details on cooling rates for immersion therapy, confirmation that anhidrosis is not diagnostic, and fluid titration to urine output for rhabdomyolysis prevention.)Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/. 

Send in your music story!A cozy studio, too many Christmas decorations, and a pair of friends ready to argue about everything that matters—and a lot that doesn't. We launch with a ridiculous “would you rather” (fight a chicken at every car door or one lion a year) and somehow end up in a serious conversation about risk, survival instincts, and how people make decisions when nothing is simple. Along the way, we get loud about regional dialects (Appalachia or Appalachian, creek or crick, pen or pin) because words are culture, and culture is identity.The conversation swerves into holiday classics, Cars rankings, and a quick tour of unlikely music heroes before the controllers come out. Red Dead Redemption 2 gets both love and side-eye for its pacing and punishing randomness. Bethesda fans will feel seen, with Fallout 4 faction hot takes and a confession that side quests often beat main plots. Then we pivot to Pokémon: performance issues in Scarlet and Violet contrasted with a newer entry's surprisingly moving side missions about grief, neglect, and second chances—proof that “kids' games” can carry real weight.Food and bodies take the spotlight in a way that's fun and a little alarming. We laugh at “now with real potatoes,” retell the great nugget switch to “real chicken,” and talk about trust and labels. A sticky vs onion-smell hypothetical opens a deeper riff on scent and attraction, including how birth control might change what we think we like. Mortality enters the chat with a debate over knowing the date or cause of your death, full-body scans, and the psychology of avoidance vs certainty. Things get darkly funny with cannibalism as a test case for ethics and preparation—stew or steak—only to return to real life with ghosts, late-night screams, and when to call or step in.It's messy, fast, and very human: a comedy-led ride that keeps landing on choice, consequence, and what our weird opinions say about us. If you love gaming debates, regional language quirks, and jokes that sneak into real questions, you'll feel right at home. Subscribe, drop your pick—lion or chicken—and leave a review with your favorite wrong pronunciation. We'll read the spiciest ones next time.Check out our Youtube and Instagram! Check out our Website! Become a member!Support the showPlease give us a quick rate and review. If you enjoyed the audio version head over to our Youtube for video content! Follow the Instagram for special content and weekly updates. Check out our website and leave us a voice message to be heard on the show or find out more about the guests!Ever wanted to start your own podcast? Here is a link to get started!https://www.buzzsprout.com/?referrer_id=1964696https://www.youtube.com/channel/UCONMXkuIfpVizopNb_CoIGghttps://www.instagram.com/hook_and_bridge_podcast/https://www.thehookandbridgepodcast.com/

What's the episode about? In this episode, hear Joshua Hurtardo Hurtardo on postmortal futures, future studies, de-growth, immortality imaginaries, future collective death, Westworld, and promoting your work in 2026 Who is Joshua?Joshua Hurtado Hurtado is a Mexican interdisciplinary researcher, currently finalising his PhD research at the University of Helsinki, Finland. He studied International Relations for his Bachelor's degree at the Tecnológico de Monterrey university,in Mexico. He obtained his first Master's degree in International Relations as well, specialising in Ideology and Discourse analysis, from the University of Essex, in the United Kingdom. He did a second Master's degree at the University of Turku, in Finland, this time in Futures Studies. After that, he began hisPhD research at the University of Helsinki, Finland, in Interdisciplinary Environmental Sciences. He uses his expertise in several disciplines and fields of study to conduct theoretical and empirical research on the topics of death and immortality, as well as on the topics of degrowth and sustainability more generally. Scholars in the DeathStudies field will find his articles ‘Towards a postmortalsociety of virtualised ancestors? The Virtual Deceased Person and the preservation of the social bond', ‘Envisioning postmortalfutures: six archetypes on future societal approaches to seeking immortality', and ‘Exploited in immortality: Techno-capitalism and immortality imaginaries in the twenty-firstcentury' published in the journal Mortality, his article ‘Fight, or flee, the future: Affect in contrasting responses against future collective death' published in the journal Journal of Sociology, and his book chapters ‘Westworld, Morality, and Digital Afterlives' in the edited collection Depicting the Afterlife in Contemporary Film and Media: Morality, Religion and Death byAngelique Nairn, and ‘Death, Relationality, and Resistance against Necropolitical Violence in Latin America' in the upcoming edited book Decolonising Death Studies by Panagiotis Pentaris, Stacey Pitsillides and Hajar Ghorbani.  In addition to his academic trajectory, he has also worked at the Ministry of Social Development at the local level in Nuevo León, Mexico, in the roles of policy analyst and later chief of research. He has taught courses at the Undergraduate level at Tecnológico de Monterrey, in Mexico, on Business Models andEntrepreneurship (despite his insistent anti-capitalist critiques) and at the Master's level at the University of Helsinki, on Organizations and EconomicDegrowth. In his spare time, he enjoys reading, watching films and TV series, and playing with Luna, his family's dog. You can contact him via the following email addresses: joshua.hurtado.h@gmail.com (personal), and joshua.hurtado@helsinki.fi (institutional, as of January 2026). You can find him at BlueSky at @joshuahh.bsky.socialHow do I cite the episode in my research and reading lists?To cite this episode, you can use the following citation: Hurtado Hurtado, J. (2026) Interview on The Death Studies Podcast hosted by Michael-Fox, B. and Visser, R. Published 2 January 2026. Available at: www.thedeathstudiespodcast.com,DOI: 10.6084/m9.figshare.30987202What next?Check out more episodes or find out more about the hosts!Got a question? Get in touch.

In this episode of Quah (Q & A), Sal, Adam & Justin coach four Pump Heads via Zoom. Mind Pump Fit Tip: 5 Ways to Predict Mortality (NO BLOOD TEST REQUIRED). (2:27) Good and bad news for young men. (22:20) Reducing your calories without eating less by going grass-fed. (35:26) Runit is invading America. (40:16) Speaking identity into your children. (45:12) Sal has an athlete on his hands. (49:58) LMNT has single-handedly created this new electrolyte market. (52:49) #ListenerCoaching call #1 – I train hard and feel great, but I don't feel like it's translating to everyday life. What am I missing? (55:29) #ListenerCoaching call #2 – Needing some advice on my current aggressive fat loss and body recomposition journey. (1:07:55) #ListenerCoaching call #3 – What's your typical recommended rest between sets? (1:17:50) #ListenerCoaching call #4 – Needing guidance on my fitness path and seeking advice on training, macros, and whether you offer personal training. (1:25:08) Related Links/Products Mentioned Get Coached by Mind Pump, live! Visit https://www.mplivecaller.com  Visit Butcher Box for this month's exclusive Mind Pump offer!  ** New users receive their choice of NY Strip, Ribeye, or Filet Mignon in every box for a year. ** Get a free Sample Pack of LMNT's most popular drink mix flavors with any purchase! As always, LMNT offers no-questions-asked refunds on all orders. The 8-count LMNT Sample Pack doubles down on our most popular flavors: Citrus Salt, Raspberry Salt, Watermelon Salt, and Orange Salt (2 stick packs of each flavor): Visit DrinkLMNT.com/MindPump MAPS 15 Symmetry 50% off! ** Code DECEMBER50 at checkout. ** Mind Pump Store Can a 10-second balance test predict longevity? - Harvard Health Sit-to-stand: The simple test that reveals how you're ageing A brief fitness test may predict how long you'll live Push-Ups and Heart Health: What Your Fitness Level Says About Your Risk HANDGRIP DYNAMOMETER Association of Grip Strength With Risk of All-Cause Mortality, Cardiovascular Diseases, and Cancer in Community-Dwelling Populations: A Meta-analysis of Prospective Cohort Studies 45 Percent of Guys 18-25 Have Never Asked a Girl Out in Person Australian collision sport Runit makes U.S. debut with stops in SoCal Rosenthal Effect: How Expectations Shape Reality Fig and Eagle Visit Luminose by Entera for an exclusive offer for Mind Pump listeners! ** Code MPM at checkout for 10% off their order or 10% off their first month of a subscribe-and-save. ** Mind Pump #2411: How to Know You are Overtrained & Underfed, Why You May Not Feel Low Testosterone, How to Properly Cut & More (Listener Live Coaching) Mind Pump #2690: The NEW DIET Everyone Is Using For Fat Loss Mind Pump #1612: Everything You Need to Know About Sets, Reps & Rest Periods Mind Pump #2759: Progressive Overload, the Secret to Building Muscle and Burning Fat. Mind Pump Podcast – YouTube Mind Pump Free Resources People Mentioned Adam | Relationship Psychology (@attachmentadam) Instagram Scott Donnell (@imscottdonnell) Instagram Mind Pump Fitness Coaching (@mindpumppersonaltraining) Instagram

Ricky Gervais jokes about crime and punishment in his Netflix special, "Mortality".

Most people don't realize they're running on autopilot until life forces them to stop. Through the lens of ‘Memento Mori', this episode shows you how living for meaning can help you find direction, improve your overall well-being, and create a purpose-driven life. You'll learn how to use this mindset shift to support your self improvement, reduce your stress, and cultivate happiness right now. I'm joined by Karen Salmansohn, author and mindset coach, for a conversation about living for meaning and finding direction through the lens of Memento Mori. I'm revisiting this episode because its message feels especially relevant right now - how to reduce stress, stay grounded in your mindset, and create a purpose-driven life without giving up your ambition or drive. Rather than being morbid, the Memento Mori mindset offers clarity. It brings you back into the present moment and helps you make more intentional choices about who you are becoming and what truly matters. Together, we explore why traditional to-do lists often leave people feeling busy but unfulfilled, and how shifting toward values-based, identity-driven habits can support greater happiness and emotional well-being. This episode is an invitation to step out of autopilot, reconnect with what matters most, and begin living with more intention starting exactly where you are. As you listen, I invite you to reflect on this question: If your time is limited, what deserves more of your attention right now? Episode Breakdown: 00:00 Welcome to Love, Happiness & Success 00:48 The “funeral question” and how it helps you live with meaning 01:19 Memento Mori and using mortality awareness to find direction 05:29 Karen's wake-up call and the origin of Your To Die For Life 09:13 “Everything that is not given is lost” and the meaning of legacy 14:22 Aristotle on happiness vs pleasure and building a purpose-driven life 21:08 The to-die list, core values, and identity-based habits 30:22 Karen's seven core values and intentional daily choices 38:28 Mortality marbles and a mindset shift that reduces stress 46:31 Dr. Lisa's 9/11 story and choosing a more intentional life If this gives you a desire for more meaning, more clarity, or a different relationship with stress, I want to offer you something supportive. You're invited to schedule a free consultation with me or a trusted member of my team. This is a private, secure space to talk about what's been weighing on you, what you want to feel differently, and what kind of support would truly help you move forward. You'll answer just a few quick questions so we can thoughtfully match you with the right counselor or coach and help you take the next step toward a more intentional, purpose-driven life. xoxo, Dr. Lisa Marie BobbyGrowing Self

Siamo sempre più soli… anche se siamo sempre connessi

Jimmy Carr is back. Jimmy Carr is one of the most recognisable comedians on the planet: world-touring stand-up, TV host, and author - famous for brutal roasts and surgical one-liners. But in this episode, you get the sharper edge and the deeper thinking: why 2026 is going to feel like a turning point and how young men can get control back. Jimmy is one of the most respected comedians in the world: a world-touring stand-up, TV host, and author known for brutal one-liners and zero mercy… but in this episode you get the full range - savage comedy and the deeply human side. We talk about dating, masculinity, porn, cheap dopamine and why so many young men feel stuck - then we go way bigger: AI as a new “god”, the end of old institutions, how podcasts replaced mainstream media, and why politics is entering a genuinely weird new era. And then the episode turns: Jimmy opens up about grief and love - remembering Sean Lock (including the first joke Jimmy ever heard him say, and why he felt like a father figure), the impact of losing his mum Nora, and a beautiful tribute to Janey Godley and what she said about Jimmy behind the scenes. Expect to learn:Why women select for competence and what “safety” really signals.Jimmy's advice to young men: porn, risk, rejection, and building a real life The loneliness trade-off: liver damage vs social isolation How Jimmy thinks about anxiety, discipline, and “life assignment” Sean Lock's legacy — and what it's like to lose someone you built a career beside Grief, funerals, and the difference between resume virtues and eulogy virtues AI, institutions, and why the next decade could get very “interesting”and much, much more.PartnersSlaters Made To Order If you're in UK and you want a suit that fits properly — Slaters Made To Order is the move.Link: https://www.slaters.co.uk/made-to-order?gclsrc=aw.ds&gad_source=1&gad_campaignid=22326051720&gbraid=0AAAAADogE-bVEefnTzse9hLL0ErpEr-jF&gclid=Cj0KCQiAgbnKBhDgARIsAGCDdlckA1RBqnk3kO10XoXEjj-ilOMcplqUquwYMtHBJtNjWRY75T_TcmkaAlhZEALw_wcBNeutonicFor clean focus and productivity support: Neutonic.Use code DAVID for a discount.Link: https://www.neutonic.com?sca_ref=10212353.vP3Eab049B&utm_source=uppromote&utm_medium=affiliate&utm_campaign=26377300:00 — Young Men Are Stuck01:52 — Jimmy's Back: Glasgow Banter04:18 — “Media Diet” & Mental Health07:27 — ADHD, Boundaries & Discipline08:23 — Arenas, Imposter Syndrome, Movies13:46 — Early Comedy Influences16:21 — How You Build Confidence17:32 — First Glasgow Joke (DVD Era)18:52 — Comedy = Friendship20:28 — Why Dark Humour Helps22:16 — Dating: Safety, Competence, Chemistry24:48 — Advice to Young Men: Porn, Games, Asking Girls Out27:09 — Drinking vs Isolation29:28 — Dealing Young People In: Agency Over Empathy31:35 — Trump + Debate vs Deliberation32:28 — Fourth Turning + Class Politics Flip34:31 — Podcasts Replaced Mainstream Media36:52 — “Be Of Service” — Working-Class Agency37:46 — “Woke”, Status & Suicidal Empathy39:19 — Jimmy's Come-Up: Luck + Work Ethic42:29 — Pre-Show Mindset44:32 — Jimmy's Laugh + His Mum47:48 — Sean Lock: First Meeting + Legacy53:54 — Grief, Mortality & Talking To The Dead55:18 — Funerals: Eulogy vs Résumé01:01:31 — AI, God & The Future01:04:26 — Secret Struggles: Dyslexia, Body Image, Work01:07:24 — Pax Americana Ending + The World Shifting01:10:29 — Kids, Legacy & Meaning01:13:18 — Janey Godley TributeInstagram: @davidmcintoshjrPatreon: https://www.patreon.com/c/davidmcintoshjr/aboutSubstack: https://substack.com/@davidmcintoshjr?Merch: https://originstoryclub.co.uk/

CardioNerds (Dr. Colin Blumenthal, Dr. Kelly Arps, and Dr. Natalie Marrero) discuss anti-arrhythmic drugs in the management of atrial fibrillation and atrial flutter with electrophysiologist Dr. Andrew Epstein. We discuss two major classes of anti-arrhythmic drugs, class IC and class III, as well as digoxin. Dr. Epstein explains their mechanisms of action, indications and specific patient populations in which they would be particularly helpful, efficacy, adverse side effects, contraindications, and key drug-drug interactions. We also elaborate on defining clinical trials and their clinical implications. Given the large burden of atrial fibrillation and atrial flutter in our patient population and the high prevalence of anti-arrhythmic drug use, this episode is sure to be applicable to many practicing physicians and trainees. Audio editing by CardioNerds academy intern, Grace Qiu.  Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Atrial Fibrillation PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls Anti-arrhythmic drugs should not be thought of as an alternative to ablation but, instead, should be considered an adjunct to catheter ablation.   Class IC anti-arrhythmic drugs, flecainide and propafenone, are highly efficacious for acute cardioversion and a great option for patients with infrequent episodes of AF who do not have a history of ischemic heart disease.    Class III anti-arrhythmic drugs like ibutilide, sotalol, and dofetilide, are highly effective for acute conversion; however, they require hospitalization for close monitoring during initiation and dose titration given the risk of prolonged QT.   Amiodarone should not be used as a first line agent given its toxicities, prolonged half-life, large volume of distribution, and drug-drug interactions.   Dr. Epstein notes that, “All drugs are poisons with a few beneficial side effects,” when highlighting the many adverse side effects of anti-arrhythmic drugs, particularly amiodarone, and the importance of balancing their benefit in rhythm control with their side effect profile.   Notes Notes: Notes drafted by Dr. Natalie Marrero. What are the Class IC anti-arrhythmic drugs and what indications exist for their use?   Class IC anti-arrhythmic drugs are anti-arrhythmic drugs that work by blocking sodium channels and, thereby, prolonging depolarizing.   Class IC anti-arrhythmic drugs include flecainide and propafenone.   Class IC anti-arrhythmic drugs are good agents to use in patients that have infrequent episodes of AF and do not want daily dosing as these agents can be used by patients when they feel palpitations and desire acute conversion back to sinus rhythm (“pill in the pocket” approach).    What are the adverse consequences and/or contraindications to using a class IC agent?  Class IC anti-arrhythmic agents are contraindicated in patients with a history of ischemic heart disease based on increased mortality associated with their use in these patients in the CAST trial.   Given the results of the CAST trial, providers should screen annually for ischemia via a functional stress test in patients on these drugs at risk for coronary disease.   These drugs can increase 1:1 conduction of atrial flutter and, therefore, require concomitant use of a beta blocker.   These agents are generally well-tolerated without any organ toxicities; however, they can precipitate heart failure in patients with cardiomyopathies, cause sinus node depression, and unmask genetic arrythmias such as a Brugada pattern.   What are the class III agents and what are indications for their use?   Class III agents are drugs that block the potassium channel, prolonging the QT, and include Ibutilide, Sotalol, and Dofetilide.    Class III agents can be considered in patients with or without a history of ischemic heart disease that desire effective acute chemical cardioversion and are willing to go to the hospital for close monitoring during dose initiation and titration.   Other specific circumstances in which one can use these agents, specifically Ibutilide, are in patients with recurrent atrial fibrillation and Wolf Parkinson White (due to slowed conduction via the accessory pathway).  What are the adverse consequences and/or contraindications to using a class III agent?  Ibutilide, Sotalol, and Dofetilide prolong the QT and increase the risk of torsade de pointes, which is why they require ECG monitoring in-patient during drug initiation and dose titration.    These agents are generally well-tolerated.   Sotalol should be avoided or used cautiously in patients with left ventricular dysfunction, while dofetilide can be used and has dose-response beneficial effects in patients with left ventricular dysfunction.   Both sotalol and dofetilide are renally cleared with specific creatinine clearance cutoffs (CrCl < 20 for dofetilide and CrCl

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Cardiovascular-Kidney-Metabolic Syndrome-Attributable Mortality in the United States, From 2010 to 2023.

Justin McRoberts, musician, pastor, and author of "It's What You Make of It," shares how confronting death early in life shaped his approach to creativity and faith. Having attended over 20 funerals by age 25, McRoberts explains why understanding mortality is essential to living fully and why the cultural narrative of imperviousness keeps people from taking creative risks. He explores how opportunities—not rigid plans—defined his multi-hyphenate career, why narrative holds human lives together, and how we're taught that art is something you earn after being responsible to the system. McRoberts makes the case for flipping that script: using your gifts now, taking financial and social risks, and approaching life as something to give away rather than protect. This is a conversation about death, creativity, faith without absolutes, and why your life should be a gift. Hosted on Acast. See acast.com/privacy for more information.

In this December Classic episode of Research Insights, host Dale Hall revisits a timely and impactful conversation originally released on July 23, 2018. The episode explores the U.S. Human Mortality Database and highlights the critical value of long-term, reliable mortality records in understanding population health. As we mark Universal Health Coverage Day this December, this episode serves as a compelling reminder that strong health systems depend on strong data. From identifying mortality patterns to analyzing longevity trends, this discussion offers insights that are essential for designing equitable and sustainable health coverage for all. Listeners will hear how mortality data shapes policy and actuarial practice—and why it matters now more than ever.

It's a holly jolly solstice at the home of Winter's Bite as Orillo, Shriek, and Tessel realize that ginger bark may have some bite.Come join us on Discord:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://discord.gg/ntaEjvc⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Consider supporting us on Patreon!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.patreon.com/IndoorAdventures⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Merch:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠indooradventure.red⁠⁠⁠bubble.com

This is a fan fav episode. You are living through exciting and strange times. There are so many technological advances with AI, space travel, NFTs, and a rapidly changing culture with social media, it's near impossible to just turn ‘off'. Let's admit it, FOMO is real and it keeps a lot of people connected when they're not even sure why they're connected. When was the last time you unplugged and took on a challenge you weren't sure you'd complete? How long has it been since you've sat with yourself in total silence or allowed yourself to just be bored out of your mind? Author and journalist, Michael Easter, joins me today to discuss his journey and share the lessons and insights he's gained from spending a month in the Arctic surviving. Hunting his own food, carrying heavy loads, and sitting with absolute boredom are just part of his story. As you listen to his story, it is my hope you will consider ways you step out of your comfort zone. There is something very freeing about being able to shake things up and break your routines and habits to improve the quality of your life in unconventional ways. This episode is about facing discomfort and finding new ways to challenge yourself for the better. Order Michael Easter's new book, The Comfort Crisis - ⁠https://amzn.to/3ihebjB⁠  Original air date: 8-5-2021 SHOW NOTES: 0:00 | Introduction to Michael Easter 1:05 | The Comfort Crisis Explained 3:02 | Journey to the Arctic 5:03 | Recovering from Alcohol 7:40 | Outside the Comfort Zone 8:55 | Helicopter Parenting Losing Challenges 12:16 | Touching Controversial Topics 14:53 | Challenges Surviving the Arctic 20:11 | Problem Creep 28:05 | Need for Rite of Passage 35:12 | Metaphorical Lions for Passage 41:19 | Comfort Creep & Habits 44:22 | Breaking Routine to be Present 47:45 | Discomfort and Boredom 50:00 | Benefits of Boredom 57:12 | Daily Routine 1:02:11 | Rucking & Human Design 1:14:05 | Killing His 1st Caribou 1:17:16 | Life Cycle & Mortality 1:27:16 | “This Too Shall Pass” 1:30:31 | Want to Live Forever? 1:39:12 | Assigning Meaning to Life 1:42:20 | Rites of Passage Transformation 1:46:12 | Problem Creep Comparison 1:50:34 | Finding Gratitude  Learn more about your ad choices. Visit megaphone.fm/adchoices

This week on the Working Ranch Radio Show, we kick off a two-part countdown of the Top Shows of 2025, highlighting some of the most meaningful conversations from the past year. In Part 1, we revisit shows ranked number eight through number five — discussions that challenged how we think about grazing management, calving-season decisions, long-term commitment in the cattle business, and what it takes to keep ranching viable amid labor, time, and generational pressures.   Links to Shows: #8: Ep 216: Tips for Successful Su Shows mmer Grazing w/ Dr. Allen Williams #7: Ep 230: Rethinking Your Calving Window #6: Ep 231: Markets, Mandates, and Mortality w/ Dr. Nevil Speer #5: Ep 228: Doing More with Less: Precision Ranching with Chip Kemp #workingranchmagazine #ranchlife #ranching #dayweather #weather #agweather #beef #cows #livestock #cattle #Allflex #Neogen #IngentyBeef #NewGeneration #TankToad #WorkingRanchRadio #BeefCattle #CowCalf #CattleManagement #Cattlemen #BeefProduction #RanchProfitability #RanchEconomics #CattleHealth #Ranchers #AgPodcast #RuralAmerica #GrazingManagement #CalvingSeason #ForageManagement #RanchManagement #SuccessionPlanning #DoingMoreWithLess #AgTechnology #PrecisionAg #RanchTech

In this episode of Acta Non Verba, host Marcus Aurelius Anderson sits down with Rod Yancy — entrepreneur, writer, attorney, and founder of Oath and Bootleg. Rod shares how he’s found success across multiple industries, from law and financial planning to software and now music. The conversation explores what it means to build companies that serve people, live with intention, and innovate within the modern music industry. Rod offers timeless lessons on creativity, courage, and taking action to turn vision into reality. Episode Highlights: 5:04 - The Power of Mortality in EntrepreneurshipRod discusses how contemplating mortality (memento mori) shaped his philosophy and inspired the founding of Oath, emphasizing the importance of living intentionally and making meaningful decisions. 9:39 - Overcoming the Success TrapRod and Marcus explore the “success trap” many entrepreneurs fall into—chasing money or status at the expense of fulfillment, health, and relationships, and how true success requires self-awareness and balance. 40:07 - Delegation and Leadership Lessons from Richard BransonRod shares advice from Richard Branson about the importance of delegation, empowering others, and stepping back as a leader to allow the team to thrive, even if it means feeling less “needed.” 56:00 - Empowering Artists with New Revenue StreamsRod introduces his new venture, Bootleg, which helps artists monetize live concert recordings, providing fans with unique experiences and artists with ongoing revenue, illustrating innovation and creative entrepreneurship. Rod Yancy is a serial entrepreneur, attorney, and founder of Oath, a company dedicated to helping people live intentionally by contemplating their mortality and planning their legacy. With a background in philosophy and law, Rod has built and scaled multiple businesses, including Oath Planning and Bootleg, a platform empowering artists to monetize live performances. Known for his creative approach, resilience, and commitment to meaningful work, Rod draws inspiration from both ancient philosophy and modern mentors like Richard Branson. He is passionate about fostering innovation, supporting artists, and helping others find purpose beyond financial success. Learn more about the gift of Adversity and my mission to help my fellow humans create a better world by heading to www.marcusaureliusanderson.com. There you can take action by joining my ANV inner circle to get exclusive content and information.See omnystudio.com/listener for privacy information.

Interview with Anupam B. Jena, MD, PhD, and Vishal R. Patel, MD, MPH, authors of Mortality Among Surgeons in the United States. Hosted by Jamie Coleman, MD. Related Content: Mortality Among Surgeons in the United States

Chegou o episódio escolhido por vocês! Marcela Belleza e Joanne Alves convidam Carol Millon para conversar sobe 6 clinicagens de inibidores de SGLT2, as gliflozinas:Indicações além do DMRisco de CAD euglicêmicaQuando não usar?⁠Cuidados com doença aguda (sick day) e hipovolemia⁠Cuidados pré-operatórioRisco de fratura e amputaçãoReferências:1. Bailey CJ, et al. Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled 102-week trial. BMC Med. 2013;11:43. Published 2013 Feb 20. doi:10.1186/1741-7015-11-432. Bersoff-Matcha SJ, et al. Fournier Gangrene Associated With Sodium-Glucose Cotransporter-2 Inhibitors: A Review of Spontaneous Postmarketing Cases. Ann Intern Med. 2019;170(11):764-769. doi:10.7326/M19-00853. Chang HY, et al. Association Between Sodium-Glucose Cotransporter 2 Inhibitors and Lower Extremity Amputation Among Patients With Type 2 Diabetes. JAMA Intern Med. 2018;178(9):1190-1198. doi:10.1001/jamainternmed.2018.3034 4. Clar C, et al. Systematic review of SGLT2 receptor inhibitors in dual or triple therapy in type 2 diabetes. BMJ Open. 2012 Oct 18;2(5):e001007. doi: 10.1136/bmjopen-2012-001007. PMID: 23087012; PMCID: PMC3488745.5. Das SR, et al. 2020 Expert Consensus Decision Pathway on Novel Therapies for Cardiovascular Risk Reduction in Patients With Type 2 Diabetes: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2020 Sep 1;76(9):1117-1145. doi: 10.1016/j.jacc.2020.05.037. Epub 2020 Aug 5. PMID: 32771263; PMCID: PMC7545583. 6. Fralick M, et al. Risk of amputation with canagliflozin across categories of age and cardiovascular risk in three US nationwide databases: cohort study. BMJ. 2020;370:m2812. Published 2020 Aug 25. doi:10.1136/bmj.m28127. Li D, et al. Urinary tract and genital infections in patients with type 2 diabetes treated with sodium-glucose co-transporter 2 inhibitors: A meta-analysis of randomized controlled trials. Diabetes Obes Metab. 2017;19(3):348-355. doi:10.1111/dom.128258. Neal B, et al. Rationale, design, and baseline characteristics of the Canagliflozin Cardiovascular Assessment Study (CANVAS)--a randomized placebo-controlled trial. Am Heart J. 2013;166(2):217-223.e11. doi:10.1016/j.ahj.2013.05.0079. Nyirjesy P, et al. Evaluation of vulvovaginal symptoms and Candida colonization in women with type 2 diabetes mellitus treated with canagliflozin, a sodium glucose co-transporter 2 inhibitor. Curr Med Res Opin. 2012;28(7):1173-1178. doi:10.1185/03007995.2012.69705310. Perkovic V, et al. Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy. N Engl J Med. 2019;380(24):2295-2306. doi:10.1056/NEJMoa181174411. Rosenwasser RF, et al. SGLT-2 inhibitors and their potential in the treatment of diabetes. Diabetes Metab Syndr Obes. 2013 Nov 27;6:453-67. doi: 10.2147/DMSO.S34416. PMID: 24348059; PMCID: PMC3848644.12. Sridharan K, Sivaramakrishnan G. Risk of limb amputation and bone fractures with sodium glucose cotransporter-2 inhibitors: a network meta-analysis and meta-regression. Expert Opin Drug Saf. 2025;24(7):797-804. doi:10.1080/14740338.2024.237775513. Ueda P,  et al. Sodium glucose cotransporter 2 inhibitors and risk of serious adverse events: nationwide register based cohort study. BMJ. 2018;363:k4365. Published 2018 Nov 14. doi:10.1136/bmj.k436514. Watts NB, et al. Effects of Canagliflozin on Fracture Risk in Patients With Type 2 Diabetes Mellitus. J Clin Endocrinol Metab. 2016 Jan;101(1):157-66. doi: 10.1210/jc.2015-3167. Epub 2015 Nov 18. PMID: 26580237; PMCID: PMC4701850.15. Zhuo M, et al. Association of Sodium-Glucose Cotransporter-2 Inhibitors With Fracture Risk in Older Adults With Type 2 Diabetes. JAMA Netw Open. 2021;4(10):e2130762. Published 2021 Oct 1. doi:10.1001/jamanetworkopen.2021.3076216. Emerson Cestari Marino, Leandra Anália Freitas Negretto, Rogério Silicani Ribeiro, Denise Momesso, Alina Coutinho Rodrigues Feitosa, Marcos Tadashi Kakitani Toyoshima, Joaquim Custódio da Silva Junior, Sérgio Vencio, Marcio Weissheimer Lauria, João Roberto de Sá, Domingos A. Malerbi, Fernando Valente, Silmara A. O. Leite, Danillo Ewerton Oliveira Amaral, Gabriel Magalhães Nunes Guimarães, Plínio da Cunha Leal, Maristela Bueno Lopes, Luiz Carlos Bastos Salles, Liana Maria Torres de Araújo Azi, Amanda Gomes Fonseca, Lorena Ibiapina M. Carvalho, Francília Faloni Coelho, Bruno Halpern, Cynthia M. Valerio, Fabio R. Trujilho,  Antonio Carlos Aguiar Brandão, Ruy Lyra e Marcello Bertoluci. Rastreamento e Controle da Hiperglicemia no Perioperatório – Posicionamento Conjunto da Sociedade Brasileira de Diabetes (SBD), Sociedade Brasileira de Anestesiologia (SBA) e Associação Brasileira para o Estudo da Obesidade e Síndrome Metabólica (ABESO). Diretriz Oficial da Sociedade Brasileira de Diabetes (2025). DOI: 10.29327/5660187.2025-10 , ISBN: 978-65-5941-367-6.17. Singh LG, Ntelis S, Siddiqui T, Seliger SL, Sorkin JD, Spanakis EK. Association of Continued Use of SGLT2 Inhibitors From the Ambulatory to Inpatient Setting With Hospital Outcomes in Patients With Diabetes: A Nationwide Cohort Study. Diabetes Care. 2024;47(6):933-940. doi:10.2337/dc23-112918. Mehta PB, Robinson A, Burkhardt D, Rushakoff RJ. Inpatient Perioperative Euglycemic Diabetic Ketoacidosis Due to Sodium-Glucose Cotransporter-2 Inhibitors - Lessons From a Case Series and Strategies to Decrease Incidence. Endocr Pract. 2022;28(9):884-888. doi:10.1016/j.eprac.2022.06.00619. Umapathysivam MM, Morgan B, Inglis JM, et al. SGLT2 Inhibitor-Associated Ketoacidosis vs Type 1 Diabetes-Associated Ketoacidosis. JAMA Netw Open. 2024;7(3):e242744. Published 2024 Mar 4. doi:10.1001/jamanetworkopen.2024.274420. Fleming N, Hamblin PS, Story D, Ekinci EI. Evolving Evidence of Diabetic Ketoacidosis in Patients Taking Sodium-Glucose Cotransporter 2 Inhibitors. J Clin Endocrinol Metab. 2020;105(8):dgaa200. doi:10.1210/clinem/dgaa20021. Neuen BL, Young T, Heerspink HJL, et al. SGLT2 inhibitors for the prevention of kidney failure in patients with type 2 diabetes: a systematic review and meta-analysis. Lancet Diabetes Endocrinol. 2019;7(11):845-854. doi:10.1016/S2213-8587(19)30256-622. Braunwald E. Gliflozins in the Management of Cardiovascular Disease. N Engl J Med. 2022;386(21):2024-2034. doi:10.1056/NEJMra211501123. Zinman B, Wanner C, Lachin JM, et al. Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. N Engl J Med. 2015;373(22):2117-2128. doi:10.1056/NEJMoa150472024. Neal B, Perkovic V, Mahaffey KW, et al. Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes. N Engl J Med. 2017;377(7):644-657. doi:10.1056/NEJMoa161192525. Wiviott SD, Raz I, Bonaca MP, et al. Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes. N Engl J Med. 2019;380(4):347-357. doi:10.1056/NEJMoa181238926. McMurray JJV, Solomon SD, Inzucchi SE, et al. Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction. N Engl J Med. 2019;381(21):1995-2008. doi:10.1056/NEJMoa191130327. Packer M, Anker SD, Butler J, et al. Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure. N Engl J Med. 2020;383(15):1413-1424. doi:10.1056/NEJMoa202219028. Anker SD, Butler J, Filippatos G, et al. Empagliflozin in Heart Failure with a Preserved Ejection Fraction. N Engl J Med. 2021;385(16):1451-1461. doi:10.1056/NEJMoa210703829. Heerspink HJL, Stefánsson BV, Correa-Rotter R, et al. Dapagliflozin in Patients with Chronic Kidney Disease. N Engl J Med. 2020;383(15):1436-1446. doi:10.1056/NEJMoa202481630. The EMPA-KIDNEY Collaborative Group, Herrington WG, Staplin N, et al. Empagliflozin in...

Interview with Anupam B. Jena, MD, PhD, and Vishal R. Patel, MD, MPH, authors of Mortality Among Surgeons in the United States. Hosted by Jamie Coleman, MD. Related Content: Mortality Among Surgeons in the United States

An interview with Dr. Jason Karp, Founder & CEO, Coach, Exercise Scientist and Author.For many years, I've been hearing people in the fitness industry talk about how your fitness and your physique is 80% nutrition and 20% exercise. And all you have to do is take one exercise science class, and you know that that's incorrect. And how can your nutrition be four times more important than exercise?Dr. Jason KarpInspiration for writing Can You Outrun a Donut?Five components of physical fitnessImportance of nutrition versus exerciseTwin studies on genetic determinants of body mass index Benefits of runningRunning and the human experiencePushing your body to the limitCoaching philosophyAccessibility of runningOutrunning donuts as we ageTips for fitness professionalshttps://www.movetolivemore.com/https://www.movetolivemore.com/bookhttps://www.linkedin.com/company/move-to-live-more@MovetoLiveMore 

Commentary by Dr. Jian'an Wang.

The pros and cons of natural vs synthetic vitamins; Telehealth site for ADD meds lands founder in prison; Why eradicating H. pylori may set the stage for Alzheimer's; Why integrative physicians often don't accept insurance; Far-infrared phototherapy may offer “electroceutical” treatment for dementia; Hobbies may forestall all-cause mortality—by 29%! 

#ThisMorning | Reducing the #Mortality #Risk of #Breast #Cancer | Steven Narod, MD, FRCPC, FRSC, Tier I Canada Research Chair in Breast Cancer, University of Toronto | #Tunein: broadcastretirementnetwork.com #Aging, #Finance, #Lifestyle, #Privacy, #Retirement, #Wellness

Are you good at your job but secretly burned out? In this episode, Nurse Practitioner turned Marketing Expert Lauren Leigh reveals why so many healthcare professionals get trapped in the "Zone of Excellence"—where competence and a steady paycheck keep you from finding your true purpose.Lauren shares her 15-year journey from the ER to the streets of Detroit doing harm reduction, and finally to launching her own agency, Transformative Ads. We discuss the reality of "doing more with less" in healthcare, how to identify your "Zone of Genius," and the specific marketing strategies clinicians need to build a profitable business.In this episode, we cover: Intro: Meet Lauren Leigh The reality of ER burnout: "Do more with less" The defining moment: Mortality and making the leap Advice for the stuck nurse: Self-care before the pivot The "Zone of Excellence" Trap vs. The "Zone of Genius" From bedside to business: Discovering Facebook Ads The Social Strategy RX: The S3 System for content Lauren's 3 Wisdom Gems for new entrepreneursAbout the Guest: Lauren Leigh is a Nurse Practitioner and the founder of Transformative Ads. She helps clinician entrepreneurs build profitable, purpose-driven businesses through high-level social media strategy and advertising.  Website: www.transformativeads.com  LinkedIn: www.linkedin.com/in/lauren-leigh-dnp

Reid is on vacation and has so much content to discuss. Jay Kelly, The Testament of Ann Lee, and the Gwyneth Paltrow x Jacob Elordi interview. Other topics include why Avatar still happens, Lost in Translation, and the backyard macabre of the Hudson Valley.Tere O'Connor at New York Live ArtsGwyneth Paltrow & Jacob Elordi Jonathan Bailey & David Corenswet◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠➩ WEBSITE⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ◦⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YOUTUBE ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠◦⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠INSTAGRAM⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠➩ SUPPORT:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠✨VIA VENMO!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠✨ or  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠PATREON⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠➩ REID⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ◦ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠JEREMY⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ◦ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠JACK⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠◠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠➩ withdanceandstuff@gmail.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

How does China's economic model work? Political economist Ben Norton explains the ideas behind Socialism with Chinese Characteristics, discussing China's socialist market economy, historical development, reform process, poverty reduction, industrial policy, and more. VIDEO with charts here: https://www.youtube.com/watch?v=6E89qUXTX-k Topics 0:00 Introduction 1:07 China has world's largest economy 3:01 China's economic development 3:54 Poverty reduction 6:56 Rising incomes 7:42 Life expectancy 8:57 Mortality rates 9:34 Reform and Opening Up 10:16 To get rich is glorious? 11:35 Deng Xiaoping's ideology 13:54 Primary stage of socialism 14:28 Chinese capitalists 15:54 Industrialization & urbanization 16:55 Birdcage economy (Chen Yun) 18:17 State ownership 19:40 State-owned enterprises (SOEs) 20:49 Grasp the large, let go of the small 22:22 Public property 23:16 SOE assets 24:14 Provincial & local governments 25:51 Golden shares in tech companies 26:54 Huawei, biggest worker-owned company 27:17 Rural cooperatives 29:09 Democracy in China? 31:40 Foreign investment in China 33:49 Global value chain 34:34 Foreign direct investment (FDI) 35:48 Industrial policy evolution 38:22 New quality productive forces 39:23 China's green energy revolution 40:24 World's manufacturing superpower 41:04 US deindustrialization & financialization 43:22 US bubble economy 44:37 China popped real estate bubble 46:50 Inequality & uneven development 48:31 Eras of the PRC 49:01 Common prosperity in New Era 49:34 Gini coefficient 50:26 Labor income vs capital income 51:48 Poverty alleviation 52:17 Wages of Chinese workers 52:44 Labor unions in China 55:19 USA funds anti-China labor groups 57:02 Marco Rubio takes over NED 57:32 Delivery workers 58:30 996 system is banned 59:23 Working hours in China 1:00:25 Imperialism & division of labor 1:03:51 AI & new cold war 1:04:45 Silicon Valley model: monopoly 1:05:43 Market competition in China 1:07:44 China opposes private monopolies 1:08:10 State planning 1:09:05 Cold War Two

Ed Fowler's 40-year career in fire and EMS culminates in a transformative chapter as he helps El Reno, Oklahoma, transition its EMS from private to an in-house, city-managed service—an innovative model focusing on sustainability, independence, and community trust. Ed shares his leadership philosophy grounded in accountability, clear communication, and mentoring future leaders. Amid this professional milestone, Ed confronts a life-threatening liver condition, navigating the transplant process while ensuring the EMS startup stays on course. His story offers rare insight into the human side of emergency services, touching on resilience, collaboration, and purpose when facing the edge of life itself. Beyond operational challenges, Ed's vulnerability inspires those struggling with adversity to find reasons to keep moving forward.

Drs. Jack Cush and Artie Kavanaugh preview the upcoming RNL 2026 meeting in Dallas, TX on February 7 & 8, 2026. Register at RheumNow.Live Below is the program: Saturday, February 7, 2026, 7:50 - 8:00 am Welcome & Introductions Drs. Cush and Kavanaugh 8:00 - 10:00 am POD I - Rheumatoid Arthritis: Achieving Better Outcomes 8:00 – 8:30 am Mortality in RA: A Story of Decline, Delay, or Plateau? Elena Myasoedova, MD 8:30 – 9:00 am The Mucosal Hypothesis of Rheumatoid Arthritis Kristen Demoruelle, MD 9:00 – 9:30 am ILD in RA – Recent Advances Jeffrey Sparks, MD 9:30 – 10:00 am Rheumatoid arthritis Faculty Q&A 10:00 - 10:15 am STEP 1: Placebos in Rheumatology Andreas Kerschbaumer, MD 10:15 -10:30 am STEP 2: Disease Modification in Osteoarthritis Tuhina Neogi, MD PhD 10:30 – 11:05 Break 11:05 - 12:10 pm POD II – Advancing Practice 11:05 – 11:30 am Obesity & Inflammation: Weight Management in Rheumatology Uzma Haque, MD 11:30 - 11:55 am Mitigating risk in Rheum Pts undergoing surgery Susan Goodman, MD 11:55 -12:10 pm Practice Panel Faculty Q&A 12:10 – 1:00pm Lunch 1:00 – 3:00 pm POD III – Decisions in Psoriatic Arthritis 1:00 - 1:30 pm Paradoxical Psoriasis and Strange Reactions Joseph Merola, MD 1:30 - 2:00 pm Why Do Plain X rays in Psoriatic Arthritis Arthur Kavanaugh, MD 2:00 - 2:30 pm IL-23 vs IL-17 inhibitors in PsA Andre Ribero, MD 2:30 - 3:00 pm Past, Present & Future of Gout Robert Terkeltaub, MD 3:00 - 3:30 pm Psoriatic Faculty Q&A 3:30 - 4:05 pm Break 4:05 - 4:20 pm STEP 3: Helicobacter Pylori update Byron Cryer, MD 4:20 - 4:35 pm STEP 4: History of Gout Robert Terkeltaub, MD 4:35 – 5:15 pm Keynote Address: 50 Years of Osteoporosis Michael McClung, MD 5:30 – 7:00 pm Reception Sunday, February 8, 2026 Day TOPIC Speaker 7:50-8:00 am Welcome & Introductions Drs. Cush and Kavanaugh 8:00 - 10:00 am POD IV – Staying Ahead of Spondyloarthritis 8:00 – 8:30 am Diagnosing Axial Spondyloarthritis in 2026 Denis Poddubnyy, MD 8:30 – 9:00 am Spondyloarthritis Complications Jessica Walsh, MD 9:00 – 9:30 am 2026 Advances in Spondyloarthritis Catherine Bakewell, MD 9:30 – 10:00 am Spondyloarthritis Faculty Q&A 10:00 – 10:15 am STEP 5: Asymptomatic Elevation of CK Rojit Agarwal, MD MS 10:15 – 10:30 am STEP 6: Update on Myositis Antibodies Rojit Agarwal, MD MS 10:30 – 11:05 am Break 11:05 – 12:10 am POD V – Highlights in Autoimmune Disease 11:05 - 11:35 am SMILE Study – Hydroxychloroquine in ANA+ Arthralgia Nancy Olsen, MD 11:35 – 12:05 am Sjogren's Treatment Landscape in 2026 Matthew Baker, MD 12:05 - 12:20 pm Autoimmune Faculty Q&A 12:20 – 1:25 pm POD VI - Large & Small Vessel Vasculitis 12:20 – 12:45 pm Embracing Relapses in PMR and GCA Michael Putman, MD 12:45 - 1:10 pm Small vessel vasculitis Clay Cockerell, MD 1:10 - 1:25 pm Vasculitis Faculty Q&A 1:30 pm Adjourn

Today, I'm joined once again by the incredible Dr. Bill Lawrence, a true pioneer in the field of longevity research and one of the most requested guests on this podcast. Dr. Lawrence trained directly with Professor Vladimir Khavinson—the scientist who discovered and developed bioregulator peptides—and has spent the last eight years leading some of the most exciting field research in this space.   Episode Timestamps: Welcome and introduction to Longevity Podcast ... 00:00:00 Origins and early use of bioregulator peptides in Soviet research ... 00:05:39 Organ-specific peptide mechanisms and targeting ... 00:08:28 Dr. Lawrence's collaboration with Professor Cavinson ... 00:12:17 Overview of American clinical studies and study protocols ... 00:14:13 Measuring biological age: telomeres and epigenetic markers ... 00:15:06 Key Russian studies and impact of peptides on mortality ... 00:17:00 Peptides as ultimate epigenetic switches and DNA repair ... 00:20:00 Importance of pineal and thymus peptides in protocols ... 00:22:28 Advances in peptide testing and lab beta-testing ... 00:28:05 Clinical outcomes: organ regeneration and normalized function ...00:35:54 Bioregulator peptides vs. synthetics: modulation vs. boosting ... 00:39:28 Dr. Lawrence's personal telomere and epigenetic age results ... 01:07:56 Impact of stress and meditation on telomere length ... 01:10:37 Group results: significant telomere and epigenetic age reversal ... 01:13:03 System-level organ age tracking and protocol targeting ... 01:27:14 International expansion and next steps in peptide research ... 01:37:03   Our Amazing Sponsors:   Kineon - near-infrared light helps improve circulation, oxygen delivery, and mitochondrial function, which can support focus, recovery, and even overall brain health. Visit kineon.io/NATNIDDAM and get 10% off!   BEAM Minerals - Mineral deficiency support. One shot in the morning, tastes like water, and you've just restored every essential mineral your cells are craving. Go to beamminerals.com, use code NAT20, and get 20% off your first order.   Nootropept by LVLUP - an advanced cognitive enhancement formula that combines fast-acting neuropeptides, cholinergic support, and mitochondrial-boosting compounds to sharpen mental clarity, memory, and long-term brain performance. Visit https://lvluphealth.com/ and use code NAT at checkout for 20% off.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

Send us a textDr. Matthew Laughon, Professor at University of North Carolina and NICHD Neonatal Research Network investigator, presents the landmark PDA Management Trial comparing expectant management versus active medical treatment (indomethacin, ibuprofen, or acetaminophen). The trial stopped early due to futility and safety concerns—mortality exceeded 10% in the treatment group versus 4% with expectant management, with more infection-related deaths among treated infants. Secondary outcomes (BPD, NEC, ROP) showed no differences. The study included infants with symptomatic PDAs but excluded those with severe cardiopulmonary compromise. Findings support expectant management for symptomatic PDAs through 21 days of life, aligning with recent guidelines recommending no routine treatment in the first two weeks. Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

The lung Composite Allocation Score (CAS) was implemented in 2023, and has shown to increase lung transplant rates and lower waitlist mortality. Host Alice Gallo de Moraes, MD, of the Mayo Clinic, interviews experts Mary Raddawi, MD, of Columbia University Irving Medical Center, and Amy Skiba, of the Lung Transplant Foundation, on the importance of CAS and how it has changed outcomes for lung transplant patients. 

In this episode of Quah (Q & A), Sal, Adam & Justin answer four Pump Head questions drawn from last Sunday's Quah post on the @mindpumpmedia Instagram page. Through Dec. 6th, 50% off a Reverse Dieting Strategy call with a Mind Pump coach. Visit: http://www.reversedietcall.com/  ** Code DECEMBER50 at checkout ** Mind Pump Fit Tip: How to use carbs for the gains! (2:24) The importance of being aware of how much protein you can handle at one sitting. (21:46) The mortality of pro bodybuilders. (29:50) The red-light "pump." (37:22) Cats vs Dogs. (41:40) Odds of success going into a rehab facility vs. doing it on your own. (45:59) Human safaris. (48:06) The plugged vs. the unplugged. (50:45) #Quah question #1 – How to scale back on cardio when you've done intense endurance for 15 years? (1:05:59) #Quah question #2 – How can we train our Central Nervous System to keep up a little better? Is there anything that can be done immediately after realizing we went a little too hard? (1:09:48) #Quah question #3 – How do I know if I'm getting stronger or if it's just my central nervous system adapting? Especially if I've been training for 10+ years? (1:11:44) #Quah question #4 – How do you feel about posture correctors? My son has bad forward shoulders, and he's been doing some exercises to correct them. He brought up this posture corrector, and I'm curious about your guys' thoughts. (1:13:30) Related Links/Products Mentioned Visit Joovv for an exclusive offer for Mind Pump listeners! ** Code MINDPUMP to get $50 off your first purchase. 0% financing available! ** Visit Rock Recovery Center for the exclusive offer for Mind Pump listeners! ** By filling out the form and scheduling your call, you'll also be entered for a chance to win a free 60-day scholarship at Rock Recovery Center, their premier treatment center in West Palm Beach, Florida. Don't wait—take the first step today. ** Through Dec. 6th, 50% off a Reverse Dieting Strategy call with a Mind Pump coach. Visit: http://www.reversedietcall.com/  ** Code DECEMBER50 at checkout ** Mind Pump Store Mind Pump #2644: Eight Best Carbs for Bodybuilding & More (Listener Live Coaching) Carb Cycling: A Good Way To Lose Fat? – Mind Pump Blog The Benefits Of Carb Cycling – Mind Pump Show Peter Attia IG clip Mortality in male bodybuilding athletes - Oxford Academic Dog Ownership Linked to 40% Reduced Risk of Dementia  The truth behind sick 'human safari' killings Get a free Sample Pack of LMNT's most popular drink mix flavors with any purchase! As always, LMNT offers no-questions-asked refunds on all orders. The 8-count LMNT Sample Pack doubles down on our most popular flavors: Citrus Salt, Raspberry Salt, Watermelon Salt, and Orange Salt (2 stick packs of each flavor): Visit DrinkLMNT.com/MindPump Mind Pump #2312: Five Steps to Bounce Back From Overtraining 7-Day Overtraining Rescue Guide | Free by Mind Pump Media Mind Pump Podcast – YouTube Mind Pump Free Resources People Mentioned Zach Bitter (@zachbitter) Instagram  Paul Saladino, MD (@paulsaladinomd) Instagram Peter Attia, M.D. (@peterattiamd) Instagram Tom Bilyeu (@tombilyeu)  Instagram Dave Asprey (@dave.asprey) Instagram Thomas Conrad (@realrecoverytalktom) Instagram Ben Bueno (@realrecoverytalkben) Instagram  

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden interviews Vlad Vukicevic , CEO and founder of the Better & Better, who shares his remarkable journey from childhood cancer survivor to entrepreneur in the health and wellness space. The conversation explores themes of longevity, health challenges, mental health, and innovative health products, emphasizing the importance of preventive care and personal growth.   For Audience ·       Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ !      Takeaways ·       Vlad's journey began with a cancer diagnosis at age five. ·       He underwent extensive treatment, including chemotherapy and a bone marrow transplant. ·       The experience shaped his understanding of mortality and health. ·       Vlad's family provided crucial support during his health challenges. ·       He developed a hypochondriac tendency due to his past health issues. ·       Vlad emphasizes the importance of ongoing health monitoring. ·       He founded Better and Better to innovate in health products. ·       The company focuses on integrating health benefits into everyday routines. ·       Vlad believes in continuous improvement in health and wellness. ·       He aims to make health management easier for everyone.     Chapters 00:00 Introduction to Longevity and Health 01:34 Vladimir's Early Health Challenges 04:43 The Impact of Childhood Cancer 09:06 Coping with Mortality and Mental Health 13:42 Navigating Teenage Years Post-Cancer 17:16 Ongoing Health Monitoring and Preventive Care 19:59 The Evolution of Health Awareness 22:46 Entrepreneurial Journey and Health Innovations 27:24 The Future of Health Products 32:00 Conclusion and Personal Growth   To learn more about Vlad: Website: https://www.betterandbetter.com/   Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw   Gladden Longevity Podcast Disclosures Production & Independence The Gladden Longevity Podcast and Age Hackers are produced by Gladden Longevity Podcast, which operates independently from Dr. Jeffrey Gladden's clinical practice and research at Gladden Longevity in Irving, Texas. Dr. Gladden may serve as a founder, advisor, or investor in select health, wellness, or longevity-related ventures. These may occasionally be referenced in podcast discussions when relevant to educational topics. Any such mentions are for informational purposes only and do not constitute endorsements. Medical Disclaimer The Gladden Longevity Podcast is intended for educational and informational purposes only. It does not constitute the practice of medicine, nursing, or other professional healthcare services — including the giving of medical advice — and no doctor–patient relationship is formed through this podcast or its associated content. The information shared on this podcast, including opinions, research discussions, and referenced materials, is not intended to replace or serve as a substitute for professional medical advice, diagnosis, or treatment. Listeners should not disregard or delay seeking medical advice for any condition they may have. Always seek the guidance of a qualified healthcare professional regarding any questions or concerns about your health, medical conditions, or treatment options. Use of information from this podcast and any linked materials is at the listener's own risk. Podcast Guest Disclosures Guests on the Gladden Longevity Podcast may hold financial interests, advisory roles, or ownership stakes in companies, products, or services discussed during their appearance. The views expressed by guests are their own and do not necessarily reflect the opinions or positions of Gladden Longevity, Dr. Jeffrey Gladden, or the production team. Sponsorships & Affiliate Disclosures To support the creation of high-quality educational content, the Gladden Longevity Podcast may include paid sponsorships or affiliate partnerships. Any such partnerships will be clearly identified during episodes or noted in the accompanying show notes. We may receive compensation through affiliate links or sponsorship agreements when products or services are mentioned on the show. However, these partnerships do not influence the opinions, recommendations, or clinical integrity of the information presented. Additional Note on Content Integrity All content is carefully curated to align with our mission of promoting science-based, ethical, and responsible approaches to health, wellness, and longevity. We strive to maintain the highest standards of transparency and educational value in all our communications.

The Guys Like Us is joined with Joshua Porter who is an author and pastor. In this episode we talk about the importance of dying to self as a Christian disciple. The path is not a climb of ascent through might and willpower. But rather, laying down performance and self-help for a deep reliance and trust in the good news of Jesus. Josh's book How to Die: Chaos, Mortality, and the Scandal of Christian Discipleship can be found where books are sold.

In this podcast, Regan Archibald dives into the three organ systems most crucial for longevity—the brain, heart, and muscles—focusing especially on how VO₂ max and grip strength predict long-term health and mortality risk. He shares personal fitness experiences, including using VO₂ max testing, dead hangs, and the Norwegian 4x4 interval protocol to improve cardiovascular performance and reverse age-related heart changes. Regan emphasizes practical strategies such as Zone 2 training, peptides for mitochondrial support, diagnostic testing, and building habits that protect metabolic and cardiovascular health. Through stories about his own training, his children's fitness challenges, and the Ageless Future roadmap, he encourages listeners to set ambitious 90-day health goals, improve daily exercise routines, and commit to becoming the fittest version of themselves.LIKE/FOLLOW/SUBSCRIBE AGELESS FUTURE:YouTube -https://www.youtube.com/@ReganArchibald / https://www.youtube.com/@Ageless.FutureLinkedIn: https://www.linkedin.com/in/regan-archibald-ab70b813Instagram: https://www.instagram.com/ageless.future/Facebook: https://www.facebook.com/AgelessFutureHealth/

The Father Hoods spin it back with another #throwback gem, revisiting a moment where the DJ EFN, Manny Digital, and KGB got deep about the parts of parenting most people keep quiet. Manny opens the convo with a real heart piece — the power of showing love to your kids, especially our sons, and why affection matters more than we admit. The Dads break down their own styles and how they stay intentional with them. DJ EFN jumps in with a flashback update from the time his partner was pregnant with their second child. He shared how he's wanted another daughter, handling that second-time-around calm, and the difference between first-kid chaos and seasoned parenting confidence. Then the table turns to a universal parent truth: the thoughts that keep you up at night. The future of our kids. Mortality. That heavy paternal anxiety every dad wrestles with sooner or later. Before the throwback wraps, Manny steps in with a quick flex. The Father Hoods website is officially up, locked in as the hub for all the episodes and other Father Hoods content. What You'll Hear in This Episode: [00:01:09] Real Dads Show Love Loud  [00:10:14] Girl Dad x Boy Dad [00:18:00] The Fears You Don't Say Out Loud [00:25:38] The Father Hoods HQ Launch Why Hit Play: DJ EFN, Manny Digital & KGB take fatherhood realness and turn it into a verse that sticks! Learn more about your ad choices. Visit megaphone.fm/adchoices

We review BRUEs (Brief Resolved Unexplained Events). Hosts: Ellen Duncan, MD, PhD Noumi Chowdhury, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/BRUE.mp3 Download Leave a Comment Tags: Pediatrics Show Notes What is a BRUE? BRUE stands for Brief Resolved Unexplained Event. It typically affects infants 60 days old Gestational Age: GA > 32 weeks (and Post-Conceptional Age > 45 weeks) Frequency: This is the first episode Duration: Lasted < 1 minute Intervention: No CPR performed by a trained professional Clinical Picture: Reassuring history and physical exam Management for Low Risk: Generally do not require extensive testing or admission. Prioritize safety education/anticipatory guidance. Ensure strict return precautions and close outpatient follow-up (within 24 hours). High Risk Criteria Any infant not meeting the low-risk criteria is automatically High Risk. Additional red flags include: Suspicion of child abuse History of toxin exposure Family history of sudden cardiac death Abnormal physical exam findings (trauma, neuro deficits) Management for High Risk: Requires a more thorough evaluation. Often requires hospital admission. Note: Serious underlying conditions are identified in approx. 4% of high-risk infants. Differential Diagnosis: “THE MISFITS” Mnemonic T – Trauma (Accidental or Non-accidental/Abuse) H – Heart (Congenital heart disease, dysrhythmias) E – Endocrine M – Metabolic (Inborn errors of metabolism) I – Infection (Sepsis, meningitis, pertussis, RSV) S – Seizures F – Formula (Reflux, allergy, aspiration) I – Intestinal Catastrophes (Volvulus, intussusception) T – Toxins (Medications, home exposures) S – Sepsis (Systemic infection) Workup & Diagnostics Step 1: Stabilization ABCs (Airway, Breathing, Circulation) Point-of-care Glucose Cardiorespiratory monitoring Step 2: Diagnostic Testing (For High Risk/Symptomatic Patients) Labs: VBG, CBC, Electrolytes. Imaging: CXR: Evaluate for infection and cardiothymic silhouette. EKG: Evaluate for QT prolongation or dysrhythmias. Neuro: Consider Head CT/MRI and EEG if there are concerns for trauma or seizures. Clinical Pearl: Only ~6% of diagnostic tests contribute meaningfully to the diagnosis. Be judicious—avoid “shotgunning” tests in low-risk patients. Prognosis & Outcomes Recurrence: Approximately 10% (lower than historical ALTE rates of 10-25%). Mortality: < 1%. Nearly always linked to an identifiable cause (abuse, metabolic disorder, severe infection). BRUE vs. SIDS: These are not the same. BRUE: Peaks < 2 months; occurs mostly during the day. SIDS: Peaks 2–4 months; occurs mostly midnight to 6:00 AM. Take-Home Points Diagnosis of Exclusion: You cannot call it a BRUE until you have ruled out obvious causes via history and physical. Strict Criteria: Stick strictly to the Low Risk criteria guidelines. If they miss even one (e.g., age < 60 days), they are High Risk. Education: For low-risk families, the most valuable intervention is reassurance, education, and arranging close follow-up. Systematic Approach: For high-risk infants, use a structured approach (like THE MISFITS) to ensure you don’t miss rare but reversible causes. Read More

In this conversation with entrepreneur and outsourcing leader Carmen Williams, we unpack the moment she walked into work, felt a physical “no” in her stomach, and quit her job that same day. No plan, no runway, no strategy deck—just bravery born from clarity.This episode isn't about hustle culture. It's about permission—to pivot, to shrink your life, to rebuild your identity, and to stop performing your way into burnout.We explore why corporate stability is an illusion, why minimalism creates freedom, how virtual teams scale your capacity, and why the “first hire fantasy” founders chase is usually wrong.We also talk about life after collapse—the rebirth that happens when you stop clinging to the version of yourself that was built to survive, not thrive.No hype. Just the quiet courage of starting over.TL;DR* The brave pivot: Carmen quit her job in one day after realizing life is short and fear is expensive.* Job security is riskier than entrepreneurship: One employer = one point of failure.* Minimalism is leverage: Less stuff, lower burn rate, fewer emergencies.* Founders hire the wrong “clone”: You don't need another visionary—you need a steady executor.* AI + VAs is the winning combo: AI increases the demand for great operators; it doesn't replace them (yet).* Saying “no” builds more trust than yes: Filtering clients improves ROI and reputation.What we unpack1. The moment you stop pretending you have timeCarmen's turning point came when her mother was diagnosed with a terminal illness—20 years older than her. Mortality compresses priorities.She realized: “If I knew I had 20 years left, would I stay here?”Her answer was a clean no.2. The illusion of corporate safetyDoug reflects on climbing into bigger houses and bigger bills—only to realize everything you own also owns a piece of you.Entrepreneurs face volatility monthly.Employees face catastrophe suddenly.Pick your pain.3. Minimalism as a business strategyDoug downsized from 3,800 sq ft → 560 sq ft.Less space. Fewer things. More intention.The easy life is the one with fewer dependencies.4. Why founders hire the wrong personalityEntrepreneurs imagine a “mini-me” assistant—someone spontaneous, creative, high-initiative.What they need is the opposite:A detail-driven operator who finishes what the founder starts.5. How Carmen accidentally built a 100-person outsourcing companyShe hired VAs for her own consulting practice.People kept asking for help.She kept saying no—until the market refused to let her.No website. No pitch deck. Twenty VAs anyway.6. Why AI doesn't replace VAs—it amplifies themHer teams use AI as a force multiplier, not a threat.Training loops, outside experts, and self-directed learning have made her VAs more valuable—not redundant.Memorable lines* “If you only have one income stream, you don't have stability—you have a trap.”* “Minimalism isn't aesthetic. It's leverage.”* “Your first hire shouldn't be you—it should be your opposite.”* “The day you stop pretending you have time is the day you become brave.”* “AI doesn't replace people. It replaces excuses.”GuestCarmen Williams — Founder & CEO of a global outsourcing agency supporting 100+ virtual assistants across multiple industries. Known for helping entrepreneurs scale through operational discipline, delegation frameworks, and mindset shifts around capacity and courage.LinkedIn: https://www.linkedin.com/in/carmenwilliamsau/Website: https://globalteams.com.au/Why this mattersIf you want your second life to work, you can't drag your first-life habits with you.That means:* lower burn rate* fewer possessions* more clarity* better support* braver decisions* honest self-assessmentYou can't rebuild while holding onto the version of yourself that burned out.Call to ActionIf this conversation lit something up for you, don't just let it fade. Come join me inside the Second Life Leader community on Skool. That's where I share the frameworks, field reports, and real stories of reinvention that don't make it into the podcast. You'll connect with other professionals who are actively rebuilding and leading with clarity. The link is in the show notes—step inside and start building your Second Life today.https://secondlifeleader.com This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.dougutberg.com

SPONSORS: 1) STOPBOX: Not only do you get 10% Off your entire ordernwhen you use code JULIAN at https://stopboxusa.com , but they are also giving you Buy One Get One Free for their StopBox Pro.#stopboxpod 2) EXPRESS VPN: Secure your online data TODAY by visiting http://ExpressVPN.com/JULIANDOREY PATREON: https://www.patreon.com/JulianDorey (***TIMESTAMPS in Description Below) ~ David Ferrugio is a Death Expert & YouTuber. He hosts the show, "DEAD Talks," in which he discusses grief and death with guests who have lost loved ones in a light hearted, easy to digest, and often humorous manner. DAVID's LINKS: YT: https://www.youtube.com/@deadtalkspodcast IG (PODCAST): https://www.instagram.com/deadtalkspodcast/?hl=en IG (PERSONAL): https://www.instagram.com/ferrugio/?hl=en FOLLOW JULIAN DOREY INSTAGRAM (Podcast): https://www.instagram.com/juliandoreypodcast/ INSTAGRAM (Personal): https://www.instagram.com/julianddorey/ X: https://twitter.com/julianddorey JULIAN YT CHANNELS - SUBSCRIBE to Julian Dorey Clips YT: https://www.youtube.com/@juliandoreyclips - SUBSCRIBE to Julian Dorey Daily YT: https://www.youtube.com/@JulianDoreyDaily - SUBSCRIBE to Best of JDP: https://www.youtube.com/@bestofJDP ****TIMESTAMPS**** 0:00 – Intro 1:23 – 9/11 Childhood, Losing Dad, Trauma, Dead Talks 13:44 — Child Grief, Memory Gaps, Public Attention, What to Say 23:26 — Age 12 Trauma, Last Goodbye, Gratitude Over Fear 35:06 — Fear Illusion, Cambodia Moment, Mindset, Unknown 42:15 — Mom, Anxiety Cycles, Rip Band-Aid, Living Again 52:47 — Fight-or-Flight, Bruce Lipton, Grief Recipe, Placebo 1:03:07 — 2020 Mortality, Big Questions, Info Overload, Sagan 1:14:16 — Inner Child, Insecurity, Life Lessons, Soul Contracts 1:22:28 — 3,000 Souls Joke, Reincarnation, Many Masters, Epigenetics 1:31:38 — Kendrick Lyrics, Past Life Regression, Hypnosis, Religion Mix 1:43:45 — Afterlife, Dogma, Mediumship, Scripture Interpretation 1:53:34 — Belief Defense, Groupthink, “I Don't Know,” Build Journey 2:03:10 — Grounding, Choosing Thoughts, ICU Scare, Chinese Farmer 2:14:30 — Chain Reaction, Worst → Good, NDE Home, Zero Worry 2:24:37 — NDE Peace, Nothingness, Old vs New Souls, 9/11 Sign 2:34:10 — Timing, Signs, Allowing vs Forcing, Before/After Life Split 2:43:44 — Tower 7, False Flags, Small Group Theory, Anger + Acceptance 2:52:07 — Exposure Therapy, 9/11 Footage, Unanswered Truth, Helping Others 3:01:29 — David's Work CREDITS: - Host, Editor & Producer: Julian Dorey - COO, Producer & Editor: Alessi Allaman - https://www.youtube.com/@UCyLKzv5fKxGmVQg3cMJJzyQ - In-Studio Producer: Joey Deef - https://www.instagram.com/joeydeef/ Julian Dorey Podcast Episode 359 - David Ferrugio Music by Artlist.io Learn more about your ad choices. Visit podcastchoices.com/adchoices

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Walter Green is a remarkable philanthropist, mentor, author of This Is the Moment!, and founder of the impactful "Say It Now" movement. In this episode, Walter delves into the unique insights gained from his challenging upbringing, discusses embracing mortality, and highlights the mindset of "finishing strong." He shares insights on intentionality, thinking in reverse, saying "no," prioritizing relationships, and the essence of focusing on others. The conversation focuses on the "Say It Now" movement, which stresses the importance of expressing sentiments to loved ones well before the end of life. We discuss: How Peter and Walter met through Ric Elias [3:30]; The unique perspectives and life lessons provided by Walter's challenging childhood [6:00]; Walter's harrowing experience with a sudden mental breakdown and his subsequent recovery with the help of therapy [12:15]; A diverse professional journey ending in great success [19:15]; The birth of a movement: celebrating friendships through public tributes and expressing gratitude to those who have shaped your life's journey [23:30]; Intentionality, thinking in reverse, saying "no", and other guiding principles for Walter [30:45]; Walter's global journey of gratitude on his 70th birthday, visiting friends, and creating memorable experiences [40:15]; The profound impact of acknowledging and expressing gratitude for the people who contribute to our lives [47:15]; The key elements for creating meaningful connections and cultivating deep, authentic friendships [53:15]; The "Say It Now" movement: the inspiration behind the remarkably impactful initiative [59:15]; What "finishing strong" means to Walter [1:08:15]; Finding peace at the end of life through expressing gratitude and finding purpose in serving others [1:16:45]; Resources to learn about "Say It Now" [1:27:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

In today's episode, Tim Whitaker engages in a thought-provoking conversation with Josh Porter, author of 'How to Die: Chaos, Mortality, and the Scandal of Christian Discipleship.' They explore the complexities of Christian discipleship, the rejection of Christian nationalism, and the importance of inclusivity within the faith. Josh's Website | Joshuasporter.com Chapters 06:14 The Premise of 'How to Die' and Christian Discipleship 11:44 Navigating Christian Nationalism and Cultural Contexts 20:41 Understanding Christian Discipleship in Modern Times 27:52 The Complexity of Queer Inclusion in Christianity 34:13 Orthodoxy and the Evolution of Beliefs 51:43 Bringing Heaven to Earth: A Call to Action ____________________________________________________ TNE Podcast hosts thought-provoking conversations at the intersection of faith, politics, and justice. We're part of the New Evangelical's 501c3 nonprofit that rejects Christian Nationalism and builds a better path forward, rooted in Jesus and centered on justice.  If ⁠⁠⁠⁠⁠⁠⁠⁠you'd like to support our work or get involved, visit our website: ⁠⁠⁠⁠⁠www.thenewevangelicals.com⁠⁠⁠⁠⁠  Follow Us On Instagram @thenewevangelicals  Subscribe On YouTube @thenewevangelicals This show is produced by Josh Gilbert Media | ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Joshgilbertmedia.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

How should we think about diets that claim to optimise both human and planetary health? Can a single "reference diet" really balance the complex trade-offs between nutrition adequacy, chronic disease prevention, and environmental sustainability? These questions have gained renewed attention with the release of the 2025 update to the EAT-Lancet Planetary Health Diet. The original 2019 report proposed a mostly plant-based dietary pattern designed to improve population health while staying within planetary boundaries. But since then, new data have emerged—on nutrient requirements, disease risk, and environmental modelling—that complicate many of the original assumptions. What does the updated evidence actually say about the health impacts of eating in line with this framework? How have the environmental projections changed? And what do these evolving targets mean for individuals, policymakers, and researchers trying to translate broad sustainability goals into practical dietary guidance? These are some of the questions explored in this episode of Sigma Nutrition, which examines the 2025 EAT-Lancet update, its scientific foundations, and what it reveals about the intersection of nutrition, health, and planetary sustainability. Timestamps [01:46] Focus on the 2025 EAT-Lancet report [02:27] Overview of the Planetary Health Diet [03:13] Comparing 2019 and 2025 reports [03:40] Dietary recommendations and nutrient targets [04:14] Health and environmental impacts [09:12] Scoring methods and dietary patterns [27:00] Mortality and chronic disease outcomes [40:01] Type 2 diabetes [44:13] Neuroimaging and cognitive outcomes [49:48] Conclusions and practical implications [58:55] Key ideas segment (Premium-only) Links & Resources Go to episode page (with links to studies) Join the Sigma email newsletter for free Subscribe to Sigma Nutrition Premium Alan Flanagan's Alinea Nutrition Education Hub Enroll in the next cohort of our Applied Nutrition Literacy course Report: EAT-Lancet

Darlene's childhood dream was to join the military. She didn't imagine she'd also be raising three children solo. Tune in to hear what it's like to be pregnant, breastfeed, and raise kids on your own in the Army. And to get shot in the back. Twice. ⭐️ This episode originally ran on March 7, 2016 and is a favorite from the archives. We hope you enjoy, and we'll be back next week with a brand new episode. … Recommendations from the archive #19 The Mortality of Motherhood … • Join LST+ for community and access to You Know What, another show in the Longest Shortest universe! • Follow us on Instagram • Sign up for our newsletter, where we recommend other parenting + reproductive health media • Buy books by LST guests (your purchase supports the show!) • Website: longestshortesttime.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Dan Houser is co-founder of Rockstar Games and is a legendary creative mind behind Grand Theft Auto (GTA) and Red Dead Redemption series of video games. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep484-sc See below for timestamps, transcript, and to give feedback, submit questions, contact Lex, etc. Transcript: https://lexfridman.com/dan-houser-transcript CONTACT LEX: Feedback - give feedback to Lex: https://lexfridman.com/survey AMA - submit questions, videos or call-in: https://lexfridman.com/ama Hiring - join our team: https://lexfridman.com/hiring Other - other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: Absurd Adventures: https://absurdventures.com A Better Paradise: https://www.amazon.com/exec/obidos/ASIN/B0FCYSK8VD American Caper: https://absurdventures.com/americancaper SPONSORS: To support this podcast, check out our sponsors & get discounts: Box: Intelligent content management platform. Go to https://box.com/ai UPLIFT Desk: Standing desks and office ergonomics. Go to https://upliftdesk.com/lex CodeRabbit: AI-powered code reviews. Go to https://coderabbit.ai/lex Miro: Online collaborative whiteboard platform. Go to https://miro.com/ Lindy: No-code AI agent builder. Go to https://go.lindy.ai/lex Shopify: Sell stuff online. Go to https://shopify.com/lex LMNT: Zero-sugar electrolyte drink mix. Go to https://drinkLMNT.com/lex OUTLINE: (00:00) - Introduction (01:29) - Sponsors, Comments, and Reflections (11:32) - Greatest films of all time (23:45) - Making video games (26:36) - GTA 3 (29:55) - Open world video games (32:42) - Character creation (36:09) - Superintelligent AI in A Better Paradise (45:21) - Can LLMs write video games? (49:41) - Creating GTA 4 and GTA 5 (1:01:16) - Hard work and Rockstar's culture of excellence (1:04:56) - GTA 6 (1:21:46) - Red Dead Redemption 2 (2:01:39) - DLCs for GTA and Red Dead Redemption (2:07:58) - Leaving Rockstar Games (2:17:22) - Greatest game of all time (2:22:10) - Life lessons from father (2:24:29) - Mortality (2:41:47) - Advice for young people (2:47:49) - Future of video games PODCAST LINKS: - Podcast Website: https://lexfridman.com/podcast - Apple Podcasts: https://apple.co/2lwqZIr - Spotify: https://spoti.fi/2nEwCF8 - RSS: https://lexfridman.com/feed/podcast/ - Podcast Playlist: https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4 - Clips Channel: https://www.youtube.com/lexclips

The U.S. has a physician shortage, created in part by a century-old reform that shut down bad medical schools. But why haven't we filled the gap? Why are some physicians so unhappy? And which is worse: a bad doctor or no doctor at all? SOURCES:Karen Clay, professor of economics and public policy at Carnegie Mellon University.Rochelle Walensky, physician-scientist and former director of the CDC. RESOURCES:"Medical School Closures, Market Adjustment, and Mortality in the Flexner Report Era," by Karen Clay, Grant Miller, Margarita Portnykh, and Ethan Schmick (National Bureau of Economic Research, 2025)."Application Overload — A Call to Reduce the Burden of Applying to Medical School," by Rochelle Walensky and Loren Walensky (New England Journal of Medicine, 2025)."Challenges to the Future of a Robust Physician Workforce in the United States," by Rochelle Walensky and Nicole McCann (New England Journal of Medicine, 2025)."The first step to addressing the physician shortage," by Rochelle Walensky and Nicole McCann (STAT, 2025)."Physician Workforce: Projections, 2022-2037," (National Center for Health Workforce Analysis, 2024).“Projected Estimates of African American Medical Graduates of Closed Historically Black Medical Schools,” by Kendall Campbell, Irma Corral, Jhojana Infante Linares, and Dmitry Tumin (JAMA Network, 2020)."Medical Education in the United States and Canada," by Abraham Flexner (The Carnegie Foundation for the Advancement of Teaching, 1910). EXTRAS:"Is the Air Traffic Control System Broken?" series by Freakonomics Radio (2025)."Are You Ready for the Elder Swell?" by Freakonomics Radio (2025)."Are Private Equity Firms Plundering the U.S. Economy?" by Freakonomics Radio (2023). Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.