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Sign up for weekly webinars: https://imahealth.org/weekly-webinars/ign up for weekly webinars: Weekly Webinars - Independent Medical Alliance What does the data show when Moderna's mRNA flu vaccine is evaluated using absolute measures of benefit and risk?IMA President and Chief Medical Officer Dr. Joseph Varon was joined by Dr. Peter McCullough, Nicolas Hulscher, and Dr. John Catanzaro to examine their new reanalysis of FDA clinical trial data for Moderna's mFLUSIVA (mRNA-1010).They discussed:• The vaccine's reported efficacy and absolute clinical benefit• Adverse reactions and reactogenicity seen in the clinical trials• Mortality findings highlighted in the authors' reanalysis• Why the authors believe the data raise unanswered questions about the vaccine's benefit-risk profile and continued licensureThe Independent Medical Alliance (formerly FLCCC) is a healthcare nonprofit on a mission to restore trust, integrity, and the doctor-patient relationship. Get involved by clicking below:• Donate: Support IMA: Donate for Advancements in Patient Care https://imahealth.org/donate/• Follow: Connect with Us - https://imahealth.org/contact/• Weekly Webinars: - https://imahealth.org/category/weekly-webinars/• Treatment Protocols: - https://imahealth.org/treatment-protocols/• Medical Disclaimer: https://imahealth.org/about/terms-and-conditions/
Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz Supplement: Use code MIKKIPEDIA to get 20% off your first order - go to www.curranz.co.nz or www.curranz.co.uk to order yours NZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nzEpisode SummaryCliff Harvey PhD is back on the podcast, and this one ranges widely before settling on its main subject. Cliff is a registered clinical nutritionist, qualified naturopath and strength and nutrition coach who has been in clinical practice since the late 1990s, and he founded the Holistic Performance Institute. He and Mikki open with wearables — Cliff has swapped an ageing Oura ring for an under-mattress Withings sleep analyser — before getting into whether an already-active person really needs dedicated cardio, and why Mikki has deliberately upped her carbohydrate intake for running after years of being firmly in the low-carb camp.The second half is a careful working-through of the alcohol evidence. Cliff's central point is a distinction that often gets lost: the research supports the claim that there is no healthy dose of alcohol, but that is not the same as showing there is no safe dose. He walks through why all-cause mortality is the endpoint to start from, where the cancer data genuinely does look different, and why effect sizes at low intakes are small enough to be hard to interpret. Both are clear that alcohol is a toxin and neither is advocating that anyone start drinking. What they are arguing is that absolutist public health messaging that outruns the data erodes trust, and that time spent getting people active would do more good than telling them to drink nothing at all.Key TopicsCliff's move from an ageing Oura ring to a Withings under-mattress sleep analyser, what resting heart rate and HRV are and aren't useful for, and Mikki's 59-day Garmin step streak and how it endedThe one thing they openly disagree on: Cliff argues accumulated movement at varying intensities can make structured zone two largely redundant for an already-active person, while Mikki champions aerobic work in its own right and pushes back on messaging that walking plus lifting is all anyone needsWhy Mikki has substantially increased her carbohydrate intake around running after years of being low carb, and the difference she reports in running, recovery and appetiteCliff on the research he co-authored — habitually low-carb athletes benefit from carbohydrate during exercise to essentially the same extent as high-carb athletes — and early-2000s field research at a 24-hour mountain bike event where athletes needed far more per hour than the then-accepted 60 g glucose and 90 g glucose-fructose ceilingsThe distinction the episode turns on: no healthy dose of alcohol is not the same claim as no safe dose, and why the Zhao 2023 meta-analysis is often read as saying the secondWhere the cancer data does look different, how relative risk and absolute risk come apart, and why a 5% relative increase can mean very little in absolute termsConfounding, residual confounding and abstainer bias — why abstainers can look worse in the data until you account for who stops drinking and whyGuardrails rather than prohibition: Cliff's dozen beers a month, what he used to tell clients, and why zero-tolerance messaging that diverges from the data erodes trust and tends to fail in clinical practiceCongeners, drink type and individual response, including why some people react differently to whiskey than to vodka — and why no spirit gets you out of a hangover at doseLinchpin behaviours: why both land on physical activity as the thing most worth people's limited attention, and Cliff's case for mindfulness as an effective non-diet interventionChapters00:00 Introduction03:07 Wearables, sleep tracking and step streaks10:38 Does everyone need dedicated cardio15:40 Running, mobility and upping carbohydrate18:31 Carbohydrate during exercise and low-carb dogma28:45 Alcohol guardrails and personal limits33:10 Mortality versus single disease endpoints38:51 Cancer risk, relative and absolute47:29 Confounding, abstainer bias and patterns58:46 Drinking culture and absolutist advice1:07:43 Drink type, congeners and sleep1:13:35 Linchpin behaviours and what matters most1:18:19 Take-homes, recommendations and outroGuest / ResourcesCliff Harvey PhDWebsite: cliffharvey.comHolistic Performance Institute: holisticperformance.instituteInstagram: @cliffdoggydogCliff is a registered clinical nutritionist, a qualified naturopath, and holds a diploma in fitness training and health coaching in patient care. He has over 20 years' experience as a strength and nutrition coach and has been in clinical practice since the late 1990s. His PhD research was in ketosis and ketogenesis, and Mikki helped supervise part of that pathway. In the episode he mentions that a full review on alcohol and mortality was due to go up in the Holistic Performance Institute's database of living review articles.Studies and research discussedZhao et al. (2023), Association Between Daily Alcohol Intake and Risk of All-Cause Mortality: A Systematic Review and Meta-analyses, JAMA Network Open. The meta-analysis at the centre of the conversation, drawing on 107 studies. Cliff's reading is that it shows no healthy dose, but does not establish that there is no safe dose.Health effects associated with alcohol consumption: a Burden of Proof study, Nature Health (2026). Referenced as looking at disease risk rather than mortality.Sarich et al. (2026), Alcohol-attributable cancer risk and burden estimates for Australia's updated alcohol consumption guidelines, British Journal of Cancer. This is the paper Mikki reads figures from during the episode. It reports that for every additional ten drinks per week, the risk of all cancers combined increased by 5%.The 45 and Up Study — the large Australian cohort (over 225,000 participants) that the above cancer analysis draws on, and the source of the absolute risk figures Mikki looks up live.Mendelian randomisation research on alcohol and risk, referred to in general terms rather than as a specific named study.Research on abstainer bias, which Cliff attributes to earlier work by Zhao and colleagues preceding their 2023 meta-analysis.Zinn, Harvey et al. (2023), Exercise and sports performance, a chapter in Ketogenic: The Science of Therapeutic Carbohydrate Restriction in Human Health (Elsevier). The chapter Cliff co-wrote with Caryn Zinn, and the source of his point about low-carb athletes benefiting from carbohydrate during exercise.Cliff also refers to research on Mediterranean diet and drinking patterns, on physical activity as protective against alcohol-related mortality risk, and on mindfulness as a non-diet intervention. These were discussed in general terms and no specific papers were named.People mentionedDr Eric Helms — teaches on the Holistic Performance Institute ...
Checking election stories with 36 days to go, trading heart health stories and weighing the value to Trump of occasional critics like Bill Maher acknowledging when he’s right. ---M and M Extra! If you love smart unscripted talk show chemistry, you’re in the right place. Two iconic talk radio hosts. One unfiltered daily conversation. No scripts. No spin. Just Mike Gallagher and Mark Davis breaking down the news the way it should be with zero apologies.See omnystudio.com/listener for privacy information.
Checking election stories with 36 days to go, trading heart health stories and weighing the value to Trump of occasional critics like Bill Maher acknowledging when he’s right. ---M and M Extra! If you love smart unscripted talk show chemistry, you’re in the right place. Two iconic talk radio hosts. One unfiltered daily conversation. No scripts. No spin. Just Mike Gallagher and Mark Davis breaking down the news the way it should be with zero apologies.See omnystudio.com/listener for privacy information.
Checking election stories with 36 days to go, trading heart health stories and weighing the value to Trump of occasional critics like Bill Maher acknowledging when he’s right. ---M and M Extra! If you love smart unscripted talk show chemistry, you’re in the right place. Two iconic talk radio hosts. One unfiltered daily conversation. No scripts. No spin. Just Mike Gallagher and Mark Davis breaking down the news the way it should be with zero apologies.See omnystudio.com/listener for privacy information.
This mortal must put on immortality.
In this moving conversation, Minter Dial welcomes poet Linda Ellis, whose work—most notably the widely-shared poem "The Dash"—has touched millions around the world, often at the most poignant moments of their lives. Linda Ellis reflects on her journey from a corporate environment to becoming a poet whose words are read at funerals, inscribed as tattoos, and woven into the fabric of people's daily lives. The discussion delves into the profound impact of contemplating mortality—not to dwell on death, but to enrich the meaning found within the ‘dash' between life's dates. Linda Ellis shares candidly about her own struggles with being closely associated with loss and funerals, and how she intentionally reframed her message to champion the celebration of life as much as its inevitable end. Together, they examine why, as a society, we so often shy away from conversations about death, and how embracing the finite nature of existence can inspire more authentic living. The episode also explores the art of creating poetry that is universally accessible without sacrificing emotional depth. Linda Ellis offers insights into fostering legacy, communicating authentically in both personal and professional settings, and the significance of expressing love and gratitude while there is still time. Whether you seek greater meaning in daily routines, guidance in dealing with loss at work, or simply a nudge to live more intentionally, this conversation offers warmth, wisdom, and practical inspiration. Join Minter Dial and Linda Ellis as they discuss the delicate balance between silliness and seriousness, and invite listeners to consider: how will you spend your own dash?
Death has a way of snapping everything back into focus. In this episode of The Impossible Life Podcast, Nick Surface and former Navy SEAL Garrett Unclebach confront a subject most people spend their lives avoiding: mortality. Whether it comes through losing someone you love, witnessing tragedy, facing danger, or simply realizing that your time is limited, these “mortality moments” reveal what you actually believe. For Christian men, faith in Jesus should create a radically different relationship with death not because we believe we are invincible, but because we know we are eternal.The resurrection of Jesus changes the entire equation. If Christ defeated death, then death is no longer the ultimate threat, and fear no longer gets to dictate how a man lives. Biblical masculinity means structuring your life around truth before pressure forces you to react to circumstances. It means having the courage and endurance to obey God when doing the right thing is costly, refusing to quit because life becomes uncomfortable, and understanding that this earthly life is only one part of a much larger eternal story. Death may end your time here, but for the believer, it does not end your life.That perspective should create urgency, not passivity. You have one earthly life, and every day you are running out of it. So what will you do with what God has put in your hands? Build the strongest marriage you can. Love your children deeply. Pursue your purpose. Know God. Serve others. Live with faith and courage instead of allowing the fear of death to make your decisions for you. When eternity becomes real, suffering looks different, priorities become clearer, and the goal becomes simple: live a life that honors God so completely that when death comes, you have nothing left that you wish you had given.Check out VITL Peptides by clicking hereJoin a group of likeminded Impossible Life listeners in our FREE Skool community by clicking here.Get the Purpose Playbook by clicking hereGet the FREE Basic Discipline Training 30 Day Program by clicking hereJoin us in Mindset Mastery by clicking hereLevel up your nutrition with IDLife by clicking hereGET IN TOUCHSocial Media - @theimpossiblelifeEmail - info@theimpossible.life
Welcome to the latest episode (October 2026) of DOC Updates, where every month Neil Skolnik, MD and John Russell, MD review the most important articles on diabetes, obesity, and cardiometabolic disease. This month on DOC Updates: Zoungas et al; Atorvastatin, Cardiovascular Events, and Disability-free Survival in Older Adults. New England Journal of Medicine, 28 August 2026; doi.org/10.1056/NEJMoa2607314 Novartis announces Lp(a)HORIZON Phase III topline results for pelacarsen in patients with elevated Lp(a) and established cardiovascular disease (CVD), press release N. Kruger, et al; Tirzepatide and the risk of atherosclerotic cardiovascular events: population based cohort study. BMJ 2026; 394 doi.org/10.1136/bmj-2026-100011 Dufour, et al; Type 2 Diabetes and Longitudinal Changes in Cortical and Trabecular Bone Density, Microarchitecture, and Strength: The Framingham Study. Diabetes Care 2026; dc260846. doi.org/10.2337/dc26-0846 He, et al; Early Weight Loss in Impaired Glucose Tolerance Is Associated With Reduced Long-term Mortality and Cardiovascular Risk: The Da Qing Diabetes Prevention Outcome Study. Diabetes Care 2026; dc260689. doi.org/10.2337/dc26-0689 Leavens ELS, Pebley K, Smith TT, et al; Nicotine E-Cigarettes for Cigarette Smoking Cessation: Recommendations to US-Based Clinicians. JAMA. 2026;336(9):783–790. doi.org/10.1001/jama.2026.13087 Presented by: Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Chair-Department of Family Medicine, Abington Jefferson Health DOC Updates is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association's three science and medical journals—Diabetes, Diabetes Care, and Diabetes, Obesity, and CardioMetabolic CARE. Intended for practicing physicians and health care professionals, DOC Updates discusses how the latest research is relevant in clinical practice. For information about the American Diabetes Association's scholarly journals, visit diabetesjournals.org. For more about this podcast, click here.
200 episodes. Shane and AJ are back together and they have a lot to catch up on. Ibiza, Future Proof, Martinis and Mortality, and a Time Magazine article about AI that had Shane looking at sailboats. They kick things off with a Substack piece called Travel Isn't a Hobby, whether affluent people who travel constantly are actually enjoying it or just stuck on a hedonic treadmill, and the Japanese concept of misogi, doing something hard once a year and pairing it with something luxurious. Then it's on to the nScale IPO, a British company going public in New York with $140 million of its $280 million in revenue not yet materialized, and the Oura Ring IPO, where the entire $2.2 billion raise is going to pay off a VC and cover employee tax withholding rather than grow the company. A viral tweet from a researcher claiming AI will wipe out humanity sent the internet into a panic and may have derailed Anthropic's IPO timeline. Shane has a conspiracy theory about it. They close with a Reddit question from a 36-year-old woman who is already financially independent but can't figure out whether to keep running the family business her dad built. Topics covered: Travel Isn't a Hobby: the hedonic treadmill and the misogi concept Future Proof festival recap and Martinis and Mortality event nScale IPO: a house of cards built on contracts that haven't materialized Oura Ring IPO: $2.2 billion raise that goes entirely to pay off a VC and employee taxes How to read an S-1 and what the story they're telling actually means The viral AI doomsday tweet, Shane's conspiracy theory, and the race to regulate Reddit: would you keep running a profitable family business if you were already financially independent? Timestamps: 00:00 Intro, episode 200, Ibiza, Italy and Future Proof recap 03:30 Travel Isn't a Hobby: the hedonic treadmill and the misogi concept 07:00 Luxury hotels, the First Class Jerk Substack and pairing hard things with rewards 10:00 Martinis and Mortality: 15 estate plans done in one night 11:30 nScale IPO: a British AI company going public with mostly unearned revenue 15:30 Oura Ring IPO: $2.2 billion raise, none of it going to grow the company 19:00 How to read an S-1 and what investors actually love about subscriptions 22:00 Wall Street banning GLP-1s and the Oura Ring placebo sleep effect 24:00 The viral AI doomsday tweet and Shane's conspiracy theory about OpenAI and Anthropic 28:30 Reddit: financially independent but can't walk away from the family business
Feeling wired, edgy, or worn thin more days than not? Or maybe you've just come through something that hit hard and fast. Either way, stress is worth understanding rather than pushing aside. In this shorter but mighty episode, we look at the real difference between the kind of stress that helps us and the kind that wears us down. We cover why short bursts of stress can sharpen us, why the constant kind takes a toll, and what the research says about reframing a hard situation without slipping into toxic positivity. Plus a few concrete ways to get some control back when things feel like too much. We're pausing our two-part series on Walking for Vitality to bring you this playbook — we'll head back to tai chi and breathwork next week!LET'S TALK THE WALK!Join here for support, motivation and fun!Wellness While Walking Facebook pageWalking to Wellness Together Facebook GROUPWellness While Walking on InstagramWellness While Walking on ThreadsWellness While Walking on TwitterWellness While Walking website for show notes and other informationwellnesswhilewalking@gmail.comRESOURCES AND SOURCES (some links may be affiliate links)Why Zebras Don't Get Ulcers, Robert SapolskyWellness While Walking Ep. 109: Mindset Tweaks to Achieve Your Health GoalsRethinking Stress: The Role of Mindsets in Determining the Stress Response, sparq.stanford.eduDoes the Perception That Stress Affects Health Matter? The Association With Health and Mortality, pubmed.ncbi.nlm.nih.govReduction of Psychological Stress in Surgical Patients, sciencedirect.comDISCLAIMERNeither I nor many of my podcast guests are doctors or healthcare professionals of any kind, and nothing on this podcast or associated content should be considered medical advice. The information provided by Wellness While Walking Podcast and associated material, by Whole Life Workshop and by Bermuda Road Wellness LLC is for informational and entertainment purposes only. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment, and before undertaking a new health care regimen, including walking.Thanks for listening to Wellness While Walking, a walking podcast anda "best podcast for walking"!
Greg and Patrick talk Bears and Giants misery, college football, fantasy pain, turning 50, family, aging, and learning to face mortality.The Grown Ass Man Podcast is back with Episode 6, and Greg DeMarco and Patrick O'Dowd spend the first half working through football misery before eventually landing on something a little heavier: getting older, watching life move faster, and realizing that turning 50 suddenly does not feel very far away.The episode starts with the usual counting confusion before Greg and Patrick settle into an NFL check-in that proves one thing very quickly: week one is a liar. The optimism surrounding the Chicago Bears did not last long, while the New York Giants found themselves dealing with their own quarterback problems. Caleb Williams, Tyson Bagent, Jackson Dart, and Jameis Winston all become part of an early-season conversation about expectations, injuries, and how quickly football can turn hope into panic.From there, the guys move into fantasy football, where bad lineup decisions, waiver wire frustration, and tight end problems provide another reminder that nobody actually knows what they are doing. Patrick checks in on Illinois and the concerns surrounding its defense, while Greg talks about Virginia Tech's reset under James Franklin and why the Hokies feel like they are moving in the right direction even if there are still plenty of questions left to answer.The college football conversation eventually gets bigger than either team. NIL, the transfer portal, conference movement, and the money pouring into the sport have changed what college football looks like, pushing it closer and closer to a semi-professional model where rosters can change almost overnight and loyalty does not mean quite what it used to.Then the episode takes a turn.Greg talks about attending a friend's elaborate 50th birthday celebration, complete with brunch, movies, dinner, and an entire day built around a milestone birthday. The realization eventually hits that Greg is next, and what starts as a funny story becomes a conversation about age, mortality, and the weird moment when 50 stops sounding like something that happens to other people.Patrick brings his own version of that perspective through a recent visit from his parents, where trips to Salem, the Big E, bowling, and simple time together matter more now than they probably would have years ago. The conversation moves through gray hair, naps, staying active, travel, workouts, retirement talk, and the growing realization that getting older does not necessarily mean slowing down. Sometimes it just means becoming more aware of how quickly everything is moving.The Grown Ass Moments of the Week bring the episode back to family. Greg shares the story of his wife being recognized by an author at a book event, while Patrick celebrates his son getting his braces off. They are small moments compared to football seasons, career changes, and milestone birthdays, but they are also the kind of things that start carrying more weight as the years move faster.Episode 6 is about football, family, aging, and the uncomfortable realization that none of us get to avoid the clock forever. Greg and Patrick are not exactly ready to face their own mortality, but if turning 50 means more travel, more family time, staying active, and still arguing about football every week, maybe the next phase does not sound so bad.Listen to Grown Ass Man Podcast #6: Learning To Face Mortality...In Life & FootballFollow The Show@grownassmanpod@wrestlngrealist@gregdemarco44@chairshotmediaChairshot Radio Network Your home for the hardest hitting podcasts... Sports, Entertainment and Sports Entertainment!All Shows On DemandChairshot Radio Network Launched in 2017, the Chairshot Radio Network presents you with the best in sports, entertainment, and sports entertainment. Wrestling and wrestling crossover podcasts + the most interesting content + the most engaging hosts = the most entertaining podcasts you'll find! MONDAY - Bandwagon Nerds (entertainment & popular culture) TUESDAY - 4 Corners Podcast (sports) WEDNESDAY - The Greg DeMarco Show (wrestling) THURSDAY - Nefarious Means FRIDAY - DWI Podcast (Drunk Wrestling Intellect) SATURDAY - The Mindless Wrestling Podcast SUNDAY - 30 Mindless Minutes CHAIRSHOT RADIO NETWORK PODCAST SPECIALS Attitude Of Aggression Podcast: The Big Five Project (chronologically exploring WWE's PPV/PLE history), Unidentified History (Ufology), & Game Gone Wrong (Game of Thrones Universe) Chairshot Radio Network Your home for the hardest hitting podcasts... Sports, Entertainment and Sports Entertainment! All Shows On DemandAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
We all die. Are you afraid of dying? Do you embrace your own mortality? In this episode, Danny and Randy discuss embracing your mortality.Subscribe to ESP's YouTube Channel! Thanks for listening! Do you have a question you want answered in a future episode? If so, send your question to: existentialstoic@protonmail.com
Today, we're speaking to Dr Jasjot Saund, a public health registrar based in London. Title of paper: Association of the NHS Health Check with all-cause mortality: a longitudinal cohort study in primary careAvailable at: https://doi.org/10.3399/BJGP.2025.0451The NHS Health Check (NHS-HC) has been shown to improve detection and management of surrogate markers of health, such as blood pressure and cholesterol. The long-term impact, however, is less evidenced, with mortality reductions seen in a UK Biobank cohort and no mortality reduction seen in a Cochrane review of general health checks, including those outside the UK. The current study added real-world evidence from a diverse UK urban population, and a 15-year study period. Survival analysis of GP electronic health record data shows reduced mortality in those who attended an NHS-HC compared with those who did not. These findings should be interpreted cautiously given the observational nature of the study design.TranscriptThis transcript was generated using AI and has not been reviewed for accuracy. Please be aware it may contain errors or omissions.Speaker A00:00:01.440 - 00:00:58.570Hi and welcome to BJGP Interviews. I'm Nada Khan and I'm the senior research editor of the Journal. Thanks for taking the time today to listen to this podcast.In today's episode, we're talking to Dr. Jazjot Sound, a public health registrar based in London.We're here to discuss the paper she's recently published here in the BJGP titled Association of the NHS Health Check with All Cause Mortality, A Longitudinal Cohort Study in Primary Care. So thanks very much for joining us here today, Jazja.It's really great to talk about this work and I think just before we get into the study itself, we know that NHS health checks are something that most GPs will probably be very familiar with, but maybe we don't always stop and think about the evidence behind them. So, just to start off, I wonder if you can explain to us a little bit about, about what the NHS Health Check program is actually designed to do.Speaker B00:00:59.050 - 00:02:16.370Yeah, absolutely.So the NHS Health Check program was rolled out in 2009 and it's essentially a population level preventative initiative, focusing particularly on cardiovascular disease, but potentially wider as well.And so it's specifically targeted at people who are between the ages of 40 and 75 and who don't already have a, a cardiovascular disease or a known cardiovascular disease. And I think that's really important because it's targeting people who are potentially at risk or have undetected disease.And what this means is, so ultimately the health check itself, it consists of a check that's usually undertaken by primary care, so looking at lifestyle factors, modifiable risk factors, biochemical tests, as well as sort of just other general checks. And importantly, this is embedded into primary care pathways.So essentially it's ensuring that these patients are followed up if they are determined to be high risk and potentially put on prescriptions or followed up with lifestyle modifications. So that's generally what the health check is at the moment.Speaker A00:02:16.690 - 00:02:31.070Brilliant. Yeah. And I guess the big question behind this paper is, do they actually make a difference?And I wonder what did we actually know about the impact of NHS health checks before you started this work? So what was out there in the literature already?Speaker B00:02:31.550 - 00:04:07.320Yeah, so there is a, a huge amount of evidence in different parts of the health check. So you might be aware already that it's a multifaceted intervention. So there's, there's the process bits like uptake and invitation.So there's a big amount of evidence that's been telling us that it's really important that we even just the method of invitation can be really influential on who takes up the health check. But then there's also the specific parts of the check itself.So how we communicate risk to patients, for example, can have an impact on how people go home and take on lifestyle advice. And then there's the body of evidence that's closer to where this paper sits, which is looking at clinical outcomes.And there is a whole body of evidence looking at surrogate markers, so things like does it shift the marker on blood pressure or bmi. And then there's the evidence on mortality, for example, or clinical endpoints such as stroke.And so far the evidence is predominantly positive to say we do see a change in clinical outcomes.And more recently, there was a paper in 2024 which was using a UK Biobank cohort and shows that there was an impact, a positive impact on disease, end stage disease, as well as mortality. But as the paper sort of addresses, there's some gaps in this evidence, which is what we. What we hoped to fill.Speaker A00:04:07.560 - 00:04:25.280Yeah.And I guess I wondered if you could just talk us through the data used for this study, because this was a really large real world cohort from an inner city London population, wasn't it? So very different than the kind of population that might, for instance, have taken part in UK Biobank?Speaker B00:04:26.240 - 00:05:17.420Yeah, absolutely.So we thought it was really important to look at whether or not the health check was having an impact as it was being delivered in a real world population.And so we were lucky enough to look at a cohort going all the way back to when the health check was implemented in 2009 in Lambeth, which is a really ethnically diverse and socioeconomically diverse cohort. So, for example, we have a population in lambeth that is 40% non white, as opposed to, I think the UK Biobank participants were 96% white.So there's a real difference.And so we wanted to ensure that the population we looked at was representative of some of the inner city boroughs that have particular challenges around NHS health check uptake.Speaker A00:05:17.660 - 00:05:27.330Okay, so let's get into what you found. And what was the headline result when you compared people who attended at least one NHS health check with those who didn't?Speaker B00:05:28.120 - 00:05:53.320Yeah, so the headline result actually showed that there was a 32% relative risk reduction associated with the health checks on all cause mortality. So that's looking at any cause of death, but shows quite an impressive risk reduction. So that is a relative risk reduction as opposed to absolute.So it's important to note that overall the absolute rate of survival was high,.Speaker A00:05:53.750 - 00:06:03.670And that's pretty Striking, actually. So that substantially lower risk of all cause mortality, were you surprised by the size of that association? So 32% is quite big, isn't it?Speaker B00:06:03.750 - 00:06:33.490I think initially I was surprised, but then looking back at the evidence and the data that's already out there, it does fall in line with kind of what we were seeing, particularly in the UK Biobank cohort as well. I think there is sort of evidence that potentially looks at general health checks, which has shown a converse picture.But as we discussed in the paper, it's really different to how the NHS health check is delivered here. So that's definitely something to bear in mind.Speaker A00:06:33.810 - 00:06:45.250And you also looked at absolute mortality risk over 10 years and the difference seemed to be really pronounced with increasing age. So could you talk us a little bit through what you found there?Speaker B00:06:45.650 - 00:07:39.440Yeah, so we found that although the older population had a. A higher absolute risk reduction, they also had a higher absolute baseline risk of death as well.So it's really difficult to distinguish whether or not that finding was related to the health check being more beneficial in older patients or whether or not actually we see a bigger absolute reduction, because in our over 65 population there is a higher baseline risk of, of death. I think we, like, when looking back at the data population who was enrolled in 2009 at the youngest possible age were 40.And even though we had 14 years of follow up, they would only be 57 years old at this point now. So their absolute risk of death is still very low, which might be more difficult to pick up in a study like this.Speaker A00:07:39.760 - 00:08:10.860Yeah, fair enough.And I guess, you know, whenever we look at observational research, I suppose the question is whether people who attend an NHS health check are somehow different than people who don't. And that's, you know, in parallel to the studies. For instance, you know, just focusing on UK Biobank, it's sort of a different population really.And I guess people who attend a health check could potentially be more health conscious or more likely to engage with healthcare. Anyway. How did you try to account for that in this work?Speaker B00:08:11.100 - 00:09:45.530Yeah, and that's a really important point to pick up and something that's really challenging in observational data in general. But so, yeah, we really wanted to make sure we tried to adjust or account...
*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]*Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy*JOIN THE COMMUNITY*Join my Community [It's Free!]: https://bit.ly/PhysionicCommunity2*EMAIL LIST*1-2 Weekly Email of Value [It's Free!]: http://bit.ly/2AXIzK6*HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H Created with BiorenderMain Walnut-Mortality Analysis: https://www.youtube.com/watch?v=3DqCZZgDdF8&t=337s0:00 - Introduction0:45 - It's a Meee, Cholesterol!3:15 - You heard me, I called you Endothelial5:12 - A New View of Inflammation7:35 - How much to eat?References [Funding/Conflicts are provided in the free article (found in the email list and Physionic Community Article Library)][Study 1037] Rajaram S, Cofán M, Sala-Vila A, et al. Effects of walnut consumption for 2 years on lipoprotein subclasses among healthy elders: findings from the WAHA randomized controlled trial. Circulation. 2021;144:1083-1085. doi:10.1161/CIRCULATIONAHA.121.054051.[Study 1038] Wu L, Piotrowski K, Rau T, et al. Walnut-enriched diet reduces fasting non-HDL-cholesterol and apolipoprotein B in healthy Caucasian subjects: a randomized controlled cross-over clinical trial. Metabolism. 2014;63:382-391. doi:10.1016/j.metabol.2013.11.005.[Study 1039] Ros E, Núñez I, Pérez-Heras A, et al. A walnut diet improves endothelial function in hypercholesterolemic subjects: a randomized crossover trial. Circulation. 2004;109:1609-1614. doi:10.1161/01.CIR.0000124477.91474.FF.[Study 1040] Katz DL, Davidhi A, Ma Y, et al. Effects of walnuts on endothelial function in overweight adults with visceral obesity: a randomized, controlled, crossover trial. J Am Coll Nutr. 2012;31(6):415-423.[Study 1041] Berryman CE, Grieger JA, West SG, et al. Acute consumption of walnuts and walnut components differentially affect postprandial lipemia, endothelial function, oxidative stress, and cholesterol efflux in humans with mild hypercholesterolemia. J Nutr. 2013;143:788-794. doi:10.3945/jn.112.170993.[Study 1042] Chiang YL, Haddad E, Rajaram S, Shavlik D, Sabaté J. The effect of dietary walnuts compared to fatty fish on eicosanoids, cytokines, soluble endothelial adhesion molecules and lymphocyte subsets: a randomized, controlled crossover trial. Prostaglandins Leukot Essent Fatty Acids. 2012;87:111-117. doi:10.1016/j.plefa.2012.07.007.[Study 1043] Cofán M, Checa A, Serra-Mir M, et al. A walnut-enriched diet for 2 years changes the serum oxylipin profile in healthy older persons. J Nutr. 2024;154:395-402. doi:10.1016/j.tjnut.2023.12.007.[Study 1044] Holscher HD, Guetterman HM, Swanson KS, et al. Walnut consumption alters the gastrointestinal microbiota, microbially derived secondary bile acids, and health markers in healthy adults: a randomized controlled trial. J Nutr. 2018;148:861-867. doi:10.1093/jn/nxy004.Please use the following link to submit your critique: https://bit.ly/PhysionicCritiqueDisclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.
Dr. Wilner would love your feedback! Click here to send a text! Thanks!In this 8-minute episode, I broach the delicate and complex topic of grief and mortality. I reference two prior episodes on this topic: Episode #160 with John Dedakis and Episode #170 with Kelly Edmondson. I also discuss some of the insights from my current medical school course on the Humanities. Please let me know what you think!Please click "Fanmail" and share your feedback!If you enjoy an episode, please share with friends and colleagues. "The Art of Medicine with Dr. Andrew Wilner" is now available on Alexa! Just say, "Play podcast The Art of Medicine with Dr. Andrew Wilner!" To never miss a program, subscribe at www.andrewwilner.com. Follow me on Instagram: @seaphoto2025X: @drwilnerlinkedin.com/in/drwilner Please rate and review each episode. To contact Dr. Wilner or to join the mailing list: www.andrewwilner.com. Thanks for listening!@uthsc @drwilner @chg @yaleu #theartofmedicinewithdrandrewwilner @amazonmusic @medscape #podcastsonamazonmusic
In this episode, Dr. David Jockers breaks down the single most dangerous medication that millions of people take every day without realizing the risks: proton pump inhibitors (PPIs), commonly prescribed for acid reflux under brand names like Prilosec and Nexium. You will learn how PPIs suppress stomach acid by up to 99%, why that leads to deficiencies in B12, magnesium, calcium, zinc, iron, and fat-soluble vitamins, and what two major studies from the UK and Sweden revealed about long-term use and all-cause mortality, cancer, and heart disease. Dr. Jockers also explains why acid reflux is usually caused by too little stomach acid rather than too much, how H2 blockers compare to PPIs, simple diet and lifestyle fixes to address the root cause, and practical strategies for anyone dealing with a hiatal hernia. In This Episode: 00:00 PPIs Linked to Mortality 00:14 Podcast Intro and Help 03:03 Most Dangerous Medication 03:54 How PPIs Harm Digestion 06:19 Studies on Long Term Risk 07:15 Nutrient Deficiencies Explained 10:21 Low Acid Causes Reflux 11:54 Safer Meds and Diet Fixes 13:59 Hiatal Hernia Strategies 14:49 Key Takeaway and Wrap Up If you're tired of thin, lifeless hair and cringe at every clump in the shower drain, your hair may need more protein. Hydra Lift Volumizing Shampoo by Pureance contains wheat protein to strengthen hair follicles from deep within and betaine from sugar beets to draw moisture into your strands, leaving hair fuller, softer, and more resilient. Pureance products are USDA certified organic, so they're great for your body and the environment. Head to pureance.com and use code JOCKERS to save 35% on your entire order. If you want to support your cognitive performance and long-term heart and brain health, eating chocolate won't get you there, but CocoaVia can. This daily plant-based supplement is powered by cocoa flavanols preserved at peak potency through CocoaPro, a proprietary gentle extraction process. These flavanols help boost your natural nitric oxide production to relax your arteries and improve blood flow to your heart and brain. In the five-year COSMOS clinical trial of over 21,000 adults, participants taking 500 mg of these cocoa flavanols daily showed a 39% reduction in cardiovascular death compared to placebo. Go to cocoavia.com and use promo code DRJOCKERS for 20% off, or find CocoaVia at your local Sprouts Farmers Market. "When people have acid reflux, it's not because they have too much acid. It's because they have too little acid." ~ Dr. Jockers Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Visit pureance.com and use code JOCKERS to save 35% on Hydra Lift Volumizing Shampoo and your entire order Visit cocoavia.com and use promo code DRJOCKERS to get 20% off CocoaVia Need help getting off acid-blocking medications? Email our health coaching team at info@drjockers.com Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https://www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
Nicole Bhave, Ashwini Kerkar, and Ahmed Kamal Siddiqi discuss what inspired this study, differences in mortality trends among age groups, and the most important takeaways from the paper.
Healing is rarely clean, linear, or complete and our worth is not determined by how perfectly we overcome the difficult parts of our story. Hospital chaplain and author Joon “J.S.” Park joins Dr. Dan for a powerful conversation about generational trauma, grief, family dynamics, faith, resilience, and what it means to remain deeply human in the middle of life's hardest moments. Drawing from more than a decade of sitting alongside patients and families experiencing death, loss, addiction, abuse, conflict, and unimaginable grief, J.S. shares how his own painful childhood shaped both the vigilance he carries and his ability to remain present with intense emotion. He describes the journey of learning to transform survival skills into sources of compassion, connection, and purpose. J.S. also challenges one of the most common ideas surrounding generational trauma: that we must completely “break the cycle” in order to heal. Instead, he encourages us to recognize moments of liberation, build circles of safety, and extend compassion toward ourselves when old patterns remain difficult to escape. Dr. Dan and J.S. explore the pressure created by rigid expectations about what a successful life, healed person, good parent, or healthy family is supposed to look like. They discuss why allowing ourselves to be imperfect can soften self-judgment and why presence, authenticity, intuition, and genuine human connection can sometimes matter more than saying or doing exactly the “right” thing. J.S. also reflects on becoming a father, returning to therapy, and his desire to make his own body a safe home so that he can become a source of safety for his wife and children. His children have given him another reason to confront his past—but he is also learning to be brave for the younger versions of himself who once needed that same protection. The conversation also explores J.S.'s evolving relationship with faith, his calling as a hospital chaplain, and his latest book, We Are Made of Us: Uncovering Our Hidden Family Dynamics, Rewriting Our Stories, and Returning to Ourselves. Ultimately, this episode offers permission to stop measuring healing against an impossible standard. Sometimes growth is found in trying. Sometimes it is found in a moment of relief, a safe relationship, or simply allowing ourselves to be exactly where we are. KEY TAKEAWAYS Healing is not binary. Breaking a generational cycle does not always happen in one dramatic moment. Small periods of safety, relief, and liberation matter. Survival skills can become strengths. The vigilance created by trauma can carry real costs while also developing capacities such as empathy, awareness, and resilience. Rigid expectations increase suffering. Measuring ourselves against an ideal version of success, healing, parenting, or life can intensify self-judgment. Presence is powerful. Sometimes the greatest gift we can offer another person is our full attention, compassion, and willingness to stay with them in a difficult moment. Authenticity can matter more than perfection. Experience and wisdom can give us the courage to move beyond scripts and respond to another human being with genuine care. We do not have to wait for crisis. Mortality often exposes unresolved family dynamics, but reflection, connection, and healing can begin long before the unthinkable happens. Compassion belongs in the healing process. People caught in painful family patterns or cycles need curiosity and understanding—not contempt for failing to simply “break free.” For more information visit https://jspark3000.com/ and follow https://www.instagram.com/jspark3000/ on Instagram. Please listen, follow, rate, and review Make It a Great One on Apple Podcasts, Spotify, or wherever you listen to podcasts. Follow @drdanpeters on social media. Visit www.drdanpeters.com and send your questions or guest pitches to podcast@drdanpeters.com. We have this moment, this day, and this life—let's make it a great one.– Dr. Dan Learn more about your ad choices. Visit podcastchoices.com/adchoices
Chris just turned 40, and he's handling it extremely well (trust us!). So naturally, we're investigating why this particular birthday became synonymous with existential dread, midlife crises, collapsing bodies, and the horrifying realization that the clock is ticking.Along with writer Gaby Moss, co-author of "The Midlife Plot Twist: How to Reboot Your Life Without Burning It Down Even If You Really, Really Want To," we trace the strange significance of the number 40 through history, discover how “life begins at forty” went from a bestselling promise to a cultural punchline, meet the psychoanalyst who coined the midlife crisis, and find out what science says is actually happening to our bodies as we cross into middle age.SHOW NOTESGABY's BOOKBecome a supporter of this podcast: https://www.spreaker.com/podcast/scared-all-the-time--7084296/support.Get the latest episodes of our bonus show NEW FEAR UNLOCKED -- and a whole lot more! -- by supporting the show on Patreon: https://www.patreon.com/ScaredAllTheTime
Dr. T welcomes ceremonial transpersonal counselor Michael Gueron, founder of Kintu Worlds, for a conversation about combat trauma, ayahuasca, ceremonial practice, and the responsibilities involved in creating safe medicine spaces. Michael describes how military service profoundly altered his sense of self and how the loss of a fellow soldier affected his unit. After leaving the military, the symptoms of PTSD became increasingly apparent, eventually contributing to a longer search for healing. His introduction to ayahuasca in Australia became an important point in that process and ultimately led to years of personal medicine work and ceremonial facilitation. Michael and Dr. T explore the cultural dimensions of ayahuasca practice and the complexities that arise as traditional medicine moves beyond its original cultural contexts. Michael argues that different cultures bring distinct psychological patterns, histories, and ways of relating into ceremony, requiring facilitators to understand the people they serve rather than simply reproduce another culture's practices. The conversation also examines Michael's approach to ceremonial safety, including clear boundaries, protection, presence, self-knowledge, and what he describes as working from the heart. For Michael, the heart is not associated with sentimentality, but with clarity, embodied presence, and an immediate capacity to perceive what is occurring within a ceremonial space. Dr. T and Michael consider what these perspectives might mean as psychedelic therapy increasingly brings clinical psychotherapy into contact with ceremonial and spiritual frameworks. They discuss tensions between medical models and traditional approaches, the importance of ethical standards among underground practitioners, and the possibility of greater collaboration among ceremonial communities. Michael also reflects on mortality, friendship, community, and the relationships that help people endure difficult periods of life. His experiences of combat and trauma inform a perspective in which medicine work is not only concerned with individual transformation, but also with cultivating connection, responsibility, kindness, and meaningful participation in community. “You know, and this is medicine of friendship. You know, cultivate that friendship, that support. And that's what keeps us strong; and have a listening ear. Listen. We don't have to say so much. Just listen and be kind to each other, and that's it.” — Michael Gueron About Michael Gueron: Michael's journey began in Israel, where early life experiences, including military service as a member of the Israeli Paratroopers, left deep emotional wounds. Overcoming the trauma of these intense combat experiences led Michael to a profound healing journey spanning over 15 years. From studying transpersonal counseling, Shiatsu, and oriental therapies, to immersing himself in sacred plant medicine traditions in Peru and Brazil, Michael's path has been one of relentless transformation. His work with Australian acacias and master plants like Ayahuasca and Huachuma has awakened profound soul memories and a deep commitment to service. Today, Michael has facilitated thousands of individuals in their healing journeys, combining ancient wisdom with compassionate care. All Things Ayahuasca podcast Website: KintuWorlds.com Key Moments: [00:00:00] Introduction and Content Warning Truth Fairy and Dr. T open the episode with a content warning and information about supporting Punk Therapy and upcoming training opportunities. [00:02:26] Meet Michael Gueron Dr. T introduces ceremonial transpersonal counselor Michael Gueron and his background in trauma healing, meditation, traditional practices, and plant medicine. [00:05:04] Stepping Out of the Shadows Michael discusses his preference for working quietly behind the scenes and why he believes sharing knowledge publicly is increasingly important. [00:07:16] Combat Trauma and the Path to Ayahuasca Michael describes military service in Israel, his experience of PTSD, and the healing journey that eventually brought him to ayahuasca. [00:10:43] Art, Nature, and Life Before the Military Michael reflects on his early connection to creativity, nature, animals, and the landscape before entering military service. [00:13:59] Military Service as a Rite of Passage Michael explores how military training, combat, loss, and the bonds between soldiers fundamentally changed his sense of self. [00:18:48] Culture and the Western Psyche Michael and Dr. T examine how ayahuasca is moving across cultures and why different cultural and ancestral contexts shape medicine experiences. [00:23:55] Boundaries and Ceremonial Safety The conversation turns to the importance of clarity, boundaries, protection, and strong containment when facilitating medicine ceremonies. [00:28:51] Where Therapy Meets Ceremonial Practice Dr. T and Michael consider what conventional psychotherapy may encounter as psychedelic therapy increasingly intersects with spiritual and ceremonial experiences. [00:33:51] What It Means to Work From the Heart Michael distinguishes embodied presence and clarity from sentimental ideas of the heart and explains their importance in his ceremonial practice. [00:37:17] Perception and Presence in Ceremony Michael describes his auditory and intuitive ways of tracking what is occurring for individuals and within the wider ceremonial space. [00:42:25] Working Across Cultures and Worldviews Michael discusses ancestry, cultural understanding, human connection, and finding common ground when working with people from different backgrounds. [00:46:35] Mortality, Fear, and Meaning Michael reflects on encounters with death and how awareness of mortality can change the way people understand fear, life, and medicine work. [00:48:59] The Future of Ayahuasca and Psychedelic Medicine Dr. T and Michael discuss legalization, medical models, ceremonial traditions, and possible pathways toward greater recognition of ayahuasca practice. [00:58:14] Friendship, Community, and Kindness Michael closes with a call for connection, listening, friendship, and simple acts of kindness as forms of medicine within communities. __ Contact Punk Therapy: Patreon: Patreon.com/PunkTherapy Website: PunkTherapy.com Email: info@punktherapy.com Contact Truth Fairy: Email: Truth@PunkTherapy.com Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this episode of Wellness You Way, I'm diving into a topic that is incredibly common but still widely misunderstood: what was formerly called PCOS and is now referred to in this episode as PMOS. I'll explain what the name change means, how PMOS is diagnosed, why insulin resistance is such an important piece of the puzzle, and why you can have PMOS at any body size. We'll also talk about the functional nutrition strategies I use to support women with PMOS, including nutrition, blood sugar regulation, strength training, sleep, stress management, targeted supplementation, and more. Before we get into that, I'm also sharing new research on why preserving muscle mass may be much more important for long-term health than simply focusing on the number on the scale.Links mentioned during this episode:PCOS/PMOS blog post: https://www.thelyonsshare.org/2026/09/15/the-root-causes-of-pcos-pmos-insulin-resistance-hormones-how-to-feel-better/Body Composition and Mortality study: https://www.ifm.org/articles/body-composition-mortality-risk-and-the-impact-of-lifestyleFree Initial Consultation with Dr. Megan: https://p.bttr.to/3a9lfYkJoin our free weekly newsletter: www.thelyonsshare.org/newsletterInstagram: www.instagram.com/thelyonsshareLyons' Share website: www.thelyonsshare.org
TODAY ON THE ROBERT SCOTT BELL SHOW: Ohio School Unvacated Expulsions, ADHD Gut Connection, Plastic Autism Link, Autistic Early Mortality, CDC mRNA Vaccine Rejection, Censorship Evolution, Public Health Obsession, Kennedy Blasts Dem Party, and MORE! https://robertscottbell.com/ohio-schools-unvacated-expulsions-adhd-gut-connection-plastic-autism-link-autism-early-mortality-moderna-cdc-mrna-flu-vaccine-rejection-censorship-evolution-public-health-non-obsession-kenned/ Purpose and Character The use of copyrighted material on the website is for non-commercial, educational purposes, and is intended to provide benefit to the public through information, critique, teaching, scholarship, or research. Nature of Copyrighted Material Weensure that the copyrighted material used is for supplementary and illustrative purposes and that it contributes significantly to the user's understanding of the content in a non-detrimental way to the commercial value of the original content. Amount and Substantiality Our website uses only the necessary amount of copyrighted material to achieve the intended purpose and does not substitute for the original market of the copyrighted works. Effect on Market Value The use of copyrighted material on our website does not in any way diminish or affect the market value of the original work. We believe that our use constitutes a 'fair use' of any such copyrighted material as provided for in section 107 of the U.S. Copyright Law. If you believe that any content on the website violates your copyright, please contact us providing the necessary information, and we will take appropriate action to address your concern.
On Kim on a Whim, Kim St. Ange and Marc Cox discuss media reports from TMZ surrounding the death of actress Hayden Panettiere, who reportedly passed away after consuming a counterfeit oxycodone pill laced with fentanyl. The hosts analyze broader public health statistics from the Centers for Disease Control and Prevention (CDC), examining synthetic opioid mortality trends and border enforcement measures. The segment transitions into local hunting updates with the opening of Missouri's bow season. LISTEN TO 97.1 FM TALK LIVE IN ST LOUIS OR STREAM WORLDWIDE AT 971TALK.COM #971FMTalk #StLouis #STLNews #KimonAWhim #PublicHealth #BorderSecurity
This episode is a replay from The Existential Stoic library. Enjoy! How often do you think about death and your own mortality? Are you afraid of dying? Are you worried you'll have regrets at the end of your life? In this episode, Danny and Randy discuss the fear of death.Subscribe to ESP's YouTube Channel! Thanks for listening! Do you have a question you want answered in a future episode? If so, send your question to: existentialstoic@protonmail.com
What if avoiding the sun carries health risks of its own?In this episode, Drs. May and Tim revisit the relationship between sunlight, cholesterol, statins, and longevity. They unpack a large Swedish observational study linking low sun exposure with higher mortality and question whether conventional advice has oversimplified the role of sunlight in human health.From vitamin D and cholesterol to skin cancer concerns and cardiovascular risk, this conversation explores why the full picture may be more complicated than “sun bad, statins good.”In this episode:What a Swedish study found about sun exposure and mortalityWhy observational research shows association—not causationHow sunlight supports vitamin D production and other biological processesThe complicated relationship between cholesterol, statins, and heart healthWhy absolute risk matters when evaluating medical treatmentsHow fear-based health messaging can overlook important tradeoffsThe importance of discussing your individual risks with your physicianThe takeaway? Health rarely fits into a simple headline. Get informed, understand your personal risk factors, and make decisions based on the complete picture—not fear.
Mental health and dementia advocate Jordan Adams grew up watching Frontotemporal Dementia slowly take his mum away. Years later, a genetic test revealed that he carries the same mutation.Jordan shares the unique grief of losing someone while they're still here, and what it means to live knowing he may develop the same disease that took his mum.But rather than allowing that uncertainty to define his life, Jordan has turned it into a reason to live more fully. He talks about finding purpose through advocacy, carrying his mum's spirit with him, and why his diagnosis has become what he calls a “license to live”.This is a conversation about grief, mortality, purpose, and choosing what you do with the time you have.Themes: Frontotemporal Dementia, Grief, Genetic Testing, Mortality, and Finding Purpose.Learn more about Jordan's work:Jordan and his brother Cian share their story, raise awareness of FTD and support fundraising for dementia research through The FTD Brothers - https://theftdbrothers.comRandox
Technology & AI scientist and advisor at Matt Kuperholz Consultancy Professor Matt Kuperholz joined Ross Stevenson and Russel Howcroft to discuss why one in three people believe AI will eventually contribute to a mass mortality event that kills nearly a billion people.See omnystudio.com/listener for privacy information.
Welcome to the latest Midlife Minute. Today, I'm answering listeners' questions about cardiovascular risk, focusing on Lp(a), LDL, statins, and the changes women experience after menopause. Stay tuned for more! IN THIS EPISODE, YOU WILL LEARN: Why women should have their Lp(a) checked both before and after menopause How Lp(a) works as a risk enhancer, and how cardiovascular risk becomes more significant when elevated Lp(a) occurs alongside high LDL Why family history is particularly helpful for women with a 10-year calculated cardiovascular risk that looks reassuringly low I review the current guidelines for primary prevention Why, even though research has shown reductions in major cardiac events with GLP-1s, GLP-1s do not replace statins for lowering LDL What a CAC score can reveal about coronary artery calcification, and what it cannot detect How AI-assisted CT angiography (such as Clearly) can map, quantify, and characterize plaque throughout the coronary branches Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line References: 1. Lipoprotein(a) and Women's Cardiovascular Health: A Review. JACC. Advances. 2026. Michos ED, Saucier S, Mehran R, Koschinsky ML.Recent 2. Sex Differences of Lipoprotein(a) Levels and Associated Risk of Morbidity and Mortality by Age: The Copenhagen General Population Study. Atherosclerosis. 2022. Simony SB, Mortensen MB, Langsted A, et al. 3. Managing Atherosclerotic Cardiovascular Risk in Young Adults: JACC State-of-the-Art Review. Journal of the American College of Cardiology. 2022. Stone NJ, Smith SC, Orringer CE, et al.Review 4. Thirty-Year Risk of Cardiovascular Disease Among Healthy Women According to Clinical Thresholds of Lipoprotein(a). JAMA Cardiology. 2026. Nordestgaard AT, Chasman DI, Moorthy V, et al.RecentObservational 5. Lipoprotein(a).The Journal of the American Medical Association. 2025. Mora S, Kronenberg 6. Clinical Practice Guideline on Lipid Management for Cardiovascular Disease Risk Reduction. Department of Veterans Affairs (2026). 2026. Paul Heidenreich, Lance Spacek, Neil Gregor, et al. Guideline 7. Lipoprotein(a) and Family History Predict Cardiovascular Disease Risk. Journal of the American College of Cardiology. 2020. Mehta A, Virani SS, Ayers CR, et al.Observational 8. 2010 ACCF/AHA Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Journal of the American College of Cardiology. 2010. Greenland P, Alpert JS, Beller GA, et al.Guideline 9. Prevalence and Prognostic Implications of Coronary Artery Calcification in Low-Risk Women. The Journal of the American Medical Association. 2016. Kavousi M, Desai CS, Ayers C, et al.SR 10. Coronary Artery Calcium Scores and Risk for Cardiovascular Events in Women Classified as “Low Risk” Based on Framingham Risk Score: The Multi-Ethnic Study of Atherosclerosis (MESA). Archives of Internal Medicine. 2007. Lakoski SG, Greenland P, Wong ND, et al.Observational 11. 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Journal of the American College of Cardiology. 2019. Arnett DK, Blumenthal RS, Albert MA, et al.Guideline 12. HOPE for Rational Statin Allocation for Primary Prevention: A Coronary Artery Calcium Picture Is Worth 1000 Words. Mayo Clinic Proceedings. 2020. Orringer CE, Maki KC.Review 13. Summary of Updated Recommendations for Primary Prevention of Cardiovascular Disease in Women: JACC State-of-the-Art Review. Journal of the American College of Cardiology. 2020. Cho L, Davis M, Elgendy I, et al.Review 14. Health Maintenance in Postmenopausal Women. American Family Physician. 2025. Plesa M, Wong A, Katsaggelos E.Guideline 15. Semaglutide and Cardiovascular Outcomes by Baseline HbA1c and Change in HbA1c in People With Overweight or Obesity but Without Diabetes in SELECT. Diabetes Care. 2024. Lingvay I, Deanfield J, Kahn SE, et al.RCT 16. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes. The New England Journal of Medicine. 2023. Lincoff AM, Brown-Frandsen K, Colhoun HM, et al.RCT 17. Long-Term Weight Loss Effects of Semaglutide in Obesity Without Diabetes in the SELECT Trial. Nature Medicine. 2024. Ryan DH, Lingvay I, Deanfield J, et al.RCT 18. Interventions for the Prevention and Management of Cardiometabolic Multiple Long-Term Conditions. Lancet. 2026. Valabhji J, Hope D, Sayed NE, et al.RecentReview 19. Glucagon‐Like Peptide‐1 Receptor Agonists and Major Adverse Cardiovascular Events in Patients With and Without Diabetes: A Meta‐Analysis of Randomized‐Controlled Trials. Clinical Cardiology. 2024. Hosseinpour A, Sood A, Kamalpour J, et al.SR 20. FDA Orange Book. FDA Orange Book. 2026. 21. 10. Cardiovascular Disease and Risk Management: Standards of Care in Diabetes-2026. Diabetes Care. 2026. American Diabetes Association Professional Practice Committee for Diabetes*.RecentGuideline 22. Premature Coronary Artery Disease in Women: Sex-Specific Risk Factors, Pathogenetic Mechanisms and Clinical Implications. Annals of Medicine. 2026. Li F, Hong D, Yang M, et al.RecentReview 23. Cardiovascular Disease Risk Factors in Women: The Impact of Race and Ethnicity: A Scientific Statement From the American Heart Association. Circulation. 2023. Mehta LS, Velarde GP, Lewey J, et al.Guideline 24. Preventing CVD in Women: Common Questions and Answers. American Family Physician. 2023. Westfall E, Viere AB, Genewick JE.Review 25. Menopause Transition and Cardiovascular Disease Risk: Implications for Timing of Early Prevention: A Scientific Statement From the American Heart Association. Circulation. 2020. El Khoudary SR, Aggarwal B, Beckie TM, et al.Guideline
James Golden, aka “Bo Snerdley,” is on the air every weekday on 77WABC. Prior to that, he served as call screener, producer, and engineer for the syndicated Rush Limbaugh radio talk show.
James Golden, aka “Bo Snerdley,” is on the air every weekday on 77WABC. Prior to that, he served as call screener, producer, and engineer for the syndicated Rush Limbaugh radio talk show.
In this episode, Dorian welcomes back her friend and colleague Rick Moody to talk about his forthcoming book, The Power of Dreams in Later Life (available for pre-order now, releasing in November). Rick shares several real dreams — his own and others' — and walks through how to read them for meaning, why dreams remain vital no matter your age, and what they can teach us about self-knowledge, aging, and mortality.Key Topics Discussed:You never outgrow dreaming. Rick emphasizes that the capacity to dream — and to learn from dreams — doesn't fade with age. If anything, dreams become a richer resource as we accumulate more life to draw on."Dreams show us what we already know, but do not yet see." This is Rick's central thesis, repeated throughout the conversation as the lens for interpreting any dream.Keep a dream journal. Rick has recorded his dreams for decades and encourages listeners to write theirs down (or record them) as soon as they wake, before the details fade.Gestalt dream theory. Rick's guiding principle: assume every person, object, and detail in a dream represents some part of the dreamer.Recurring dreams and nightmares. Rick compares them to a bill collector who keeps calling until you "get the message." He advises that a nightmare recurring for years is a signal to see a psychotherapist, and stresses that dream work complements therapy but isn't a replacement for it.Mortality and "you never know when your time will come." Rick recounts being on a plane at LaGuardia Airport preparing for takeoff on September 11, 2001, and the perspective that experience gave him on aging, worry, and denial.Worry, guilt, and regret aren't always bad. Rick pushes back on the idea that these feelings should simply be eliminated — they can point us toward what actually deserves our attention.Universal dream symbols to watch for: a house with unknown rooms, losing control of a car (a steering wheel that won't work), and driving someone else's car.Closing takeaway: Be aware of your dreams, write them down, and pay attention — even if you don't often remember them. As Rick puts it, quoting Eleanor Roosevelt, "This is the oldest day you've ever been, and the youngest you'll ever be for the rest of your life."Notable Quotes:"Dreams show us what we already know, but do not yet see.""It's never too late to understand yourself.""Everything in a dream is you, the dreamer.""In dreams begin responsibilities." — W.B. Yeats, quoted by Rick"Dreams are your own internal app... an app just tells you where you are. You have to plug in where you want to go."About Rick Moody:Rick Moody is a gerontologist, author, and longtime positive aging pioneer, as well as a climate change advocate. His new book, The Power of Dreams in Later Life, is available for pre-order now and will be released in November.Connect with Rick: hrmoody@yahoo.com — he personally replies to messages from readers.What to do next:Click to grab our free guide, 10 Key Issues to Consider as You Explore Your Retirement TransitionPlease leave a review at Apple Podcasts.Join our Revolutionize Your Retirement group on Facebook.
Ralph Sutton and Marcus Antebi are back behind the mics after last week's classic episode highlighting the first episode. Getting older is inevitable. Getting better at being a human is the part we actually have some control over.This week, Ralph Sutton and Marcus Antebi talk about aging parents, mortality, relationships, meditation, gratitude, and what happens when you realize you're entering a completely different chapter of your life. Ralph opens up about his mom coming to New York at almost 80, Marcus talks about his mother's frightening fall and recovery, and somehow a conversation about getting older turns into one about how we actually want to live.We're not gurus. We don't have it all figured out. We're two lifelong friends trying to learn from our mistakes, take better care of ourselves and the people we love, and hopefully become slightly better humans along the way.If you're trying to do the same thing, you're part of this.Subscribe to goodsugar, send this episode to a friend who'd get something out of it, and come along for the journey. We've got a lot more figuring out to do.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]*Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy*JOIN THE COMMUNITY*Join my Community [It's Free!]: https://bit.ly/PhysionicCommunity2*EMAIL LIST*1-2 Weekly Email of Value [It's Free!]: http://bit.ly/2AXIzK6*HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H Original Podcast: https://youtu.be/q57CNySsYxs?si=PIwVEVGj_-cYkDCU0:00 - Introduction1:54 - Genetics that cause High Cholesterol5:29 - The American Heart Association is lying to you8:05 - Extremely High Cholesterol doesn't Kill17:48 - High Cholesterol at 60? Protection from Death25:20 - Other ways of testing this?27:12 - Main PointsReferences[1] Mundal L, Sarancic M, Ose L, et al. Mortality among patients with familial hypercholesterolemia: a registry-based study in Norway, 1992–2010. *J Am Heart Assoc*. 2014;3(6):e001236. doi:10.1161/JAHA.114.001236[2] Brown MS, Goldstein JL. Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity. *Proc Natl Acad Sci U S A*. 1974;71(3):788-792. doi:10.1073/pnas.71.3.788[3] Shishikura D, Harada-Shiba M, Michikura M, et al. Comparison of clinical characterization and therapeutic strategies between homozygous familial hypercholesterolemia and heterozygous familial hypercholesterolemia. *J Atheroscler Thromb*. 2026;33. Advance publication online March 27, 2026. doi:10.5551/jat.65959[4] Wiegman A, de Groot E, Hutten BA, et al. Arterial intima-media thickness in children heterozygous for familial hypercholesterolaemia. *Lancet*. 2004;363(9406):369-370. doi:10.1016/S0140-6736(04)15467-6[5] EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC). Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC). *Lancet*. 2021;398(10312):1713-1725. doi:10.1016/S0140-6736(21)01122-3[6] Clarke R, Emberson JR, Parish S, et al. Cholesterol fractions and apolipoproteins as risk factors for heart disease mortality in older men. *Arch Intern Med.* 2007;167(13):1373-1378.[7] Ding M, Wennberg A, Ek S, et al. The association of apolipoproteins with later-life all-cause and cardiovascular mortality: a population-based study stratified by age. *Sci Rep.* 2021;11(1):24440. doi:10.1038/s41598-021-03959-5.[8] Mortensen MB, Nordestgaard BG. Elevated LDL cholesterol and increased risk of myocardial infarction and atherosclerotic cardiovascular disease in individuals aged 70-100 years: a contemporary primary prevention cohort. *Lancet*. 2020;396(10263):1644-1652. doi:10.1016/S0140-6736(20)32233-9Please use the following link to submit your critique: https://bit.ly/PhysionicCritiqueDisclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.
Following Christ is a journey – what a wonderful journey it should be! In today's 3 chapters in 2nd Corinthians we see how Paul opens out more and more to them the wonder and challenges of this journey. We are reminded of Solomon's ‘vision' that “the path of the righteous is like the light of dawn, which shines brighter and brighter until …” [Prov. 4 v.18]! Yes, until the “full day” comes, when faith is turned to sight. Is the path you are treading, shining brighter and brighter? Are you “bringing holiness to completion”?The increasing spiritual darkness around us – should make the brightness of our path more evident! But sadly, ‘official' Christianity is showing ever more clearly that God “has blinded their eyes and hardened their heart, lest they see with their eyes, and understand with their heart, and turn …” [John 12 v.40]. The ‘evidence' was there for them to ‘see' in the days of Jesus but their minds refused to accept what their eyes saw! They were unable to “turn.” And today! The contrast between “light” and “darkness” has grown really great; those in darkness have convinced themselves there never was a Creator.We are challenged to clearly understand what Paul means! He says, “while we are still in this tent, we groan, being burdened – not that we would be unclothed, but that we would be further clothed, so that what is mortal may be swallowed up by life.” [5 v.4] The more we are “further clothed” in our minds, the pathway before us will become increasingly clear and bright. “We are always of good courage”, says Paul, “and we would rather be away from the body and present with the Lord” [v.8] Those who believe their “soul” is immortal usually misunderstand Paul's meaning. Mortality will be “swallowed up” when Christ returns as Paul explained in detail in 1 Cor. Ch. 15 also when he stated his expectation of what is “laid up for me” in 2 Tim 4 v.7,8. We will be physically “at home with the Lord” when he returns. Paul challenges them (and us) to be more and more spiritually “at home” with him now so that when we “appear before the judgement seat of Christ (when) … each one … receive(s) what is due for what he has done in the body …” [v.10] This means what he has done in “the body” of Christ – as Paul made clear in Ephesians 1 v.22,23.Chapter 6 in today's readings ends by making the Corinthians aware of God's promises of the life to come in his kingdom as recorded in the Old Testament (he quotes from Lev. 26 v.12 and Isaiah 52 v.11). Ch. 7 starts, “Since we have these promises, beloved, let us cleanse ourselves from every defilement … bringing holiness to completion in the fear (awe) of God”. He tells them to “widen your hearts” [6 v.13] How “wide” is your heart?. Our readings are the essential ‘food' for our hearts; God's scriptures are a foundation ingredient if our hearts are to really become wide and so see “the path” really clearly so that we anticipate the “full day” with the greatest eagerness.
This episode is a replay from The Existential Stoic library. Enjoy! Are you afraid of dying? Do you ever think about your own demise? Do you avoid thinking about death? In this episode, Danny and Randy discuss facing and accepting death. Listen now to hear what fears we have related to death, what we hope for, and how facing and accepting death can be freeing.Subscribe to ESP's YouTube Channel! Thanks for listening! Do you have a question you want answered in a future episode? If so, send your question to: existentialstoic@protonmail.com
Today we are diving into a topic that is incredibly close to my heart—one that has the potential to fundamentally change how we approach prenatal care and protect pregnant patients. We're talking about low-dose aspirin for the prevention of hypertensive disorders of pregnancy. Now, if you follow current formal guidelines, you probably know the standard protocol: 81 milligrams a day, prescribed based on specific risk factors. But there's a growing body of evidence suggesting we might be underdosing—and under-prescribing. What if 162 milligrams taken universally across the board is actually far more effective?In today's episode, we're unpacking a brand-new, groundbreaking study published in the American Journal of Obstetrics & Gynecology. And I'm especially excited to cover this one because it comes straight out of my alma mater, Parkland Hospital! This study takes a bold look at real-world outcomes by comparing a period of universal 162-milligram aspirin use directly against a historical period when aspirin wasn't recommended at all. Did a higher, universal dose significantly cut down on hypertensive disorders? And just as importantly …were there any adverse safety events we need to be aware of? Grab your coffee, settle in, and let's get into the details.1. Duryea E, Ambia A, Pruszynski J. et al. Universal Aspirin Dispensation for Prevention of Preeclampsia in a High-Risk Population. AJOG, 2026; ePub 8/27/282. Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists' Task Force on Hypertension in Pregnancy. Obstet Gynecol. 2013 Nov;122(5):1122-1131. 3. ACOG Issues Updated Hypertension Guidance, Discusses New ACC/AHA Criteria (2018): https://www.acog.org/news/news-releases/2018/12/acog-issues-updated-hypertension-guidance4. Low-Dose Aspirin Use During Pregnancy, ACOG Committee Opinion Number 743 (2018)5. Low-Dose Aspirin Use for the Prevention of Preeclampsia and Related Morbidity and Mortality. ACOG Practice Advisory; December 2021
Send us Fan MailIn Part One of my conversation with Scott Chesebro, we talked about a life shaped by curiosity - by people, places, questions, and a willingness to look beyond the boundaries of his own religious and cultural experience. Scott has never understood faith as simply a system of beliefs about heaven and hell. For him, it has been a way of being in community and of remaining open to the lives and experiences of others.In Part Two, our conversation becomes more intimate. Scott is living with an incurable lung disease and has made the deeply personal decision to enter hospice. Yet this is not simply a conversation about illness or dying. It is about how a person looks back on a life well lived - and what he hopes to leave behind.We talk about Norene, his partner in marriage and tireless companion; about raising their two sons on Chicago's South Side and now watching their grandchildren grow up there; about race, public schools, faith communities, and the former students who continue to visit him. We talk about travel, including a journey through West Africa and along the Slave Road, and the curiosity that has guided Scott since childhood.And eventually, we arrive at the question all of us must face: What do you want the people you love to remember?Scott's answer is both simple and profound: “I'm not afraid to die. I just don't want to leave.”SHOW NOTESSupport the showBecome a Patron - Click on the link to learn how you can become a Patron of the show. Thank you!Ken's Substack PageThe Podcast Official Site: TheBeachedWhiteMale.com
How can actuaries assess mortality and morbidity risk when historical experience may no longer fully reflect a changing climate environment? In this episode of the Research Insights Podcast, Dale Hall, Managing Director of Research at the Society of Actuaries Research Institute, welcomes Carlos Arocha, FSA, SCR, and Jérôme Crugnola-Humbert, SAV, IA, authors of the report Quantifying Mortality and Morbidity Impacts from Climate Risks: A Practical Framework for Decision-Making. Carlos and Jérôme discuss how climate hazards, population exposure and vulnerability can translate into life and health outcomes and ultimately affect actuarial decision-making. They explore why historical mortality and morbidity data alone may be insufficient in a changing risk environment, how climate-related variables can be incorporated into mortality modeling, and what a case study examining France, Italy and Spain can teach actuaries about interpreting forward-looking scenarios. The conversation also examines the "streetlight effect" and the "quantitative fallacy," along with practical considerations for life and health insurers seeking to better understand and prepare for climate-related risks. Listen to the episode and explore the full report, accompanying actuarial toolkit, and additional research from the Society of Actuaries Research Institute by visiting SOA.org and navigating to the Catastrophe & Climate research area. Read the Report: https://www.soa.org/resources/research-reports/2026/climate-mortality-morbidity-framework/
n episode 194 of the Get Reelisms podcast, filmmakers Adam Chase Rani and Christine Chen discuss Christine's recent health crisis: after an MRI on May 1, doctors found a brain tumor, and she is scheduled for surgery on May 19 to remove it. Christine describes sporadic focal seizures starting the previous summer, including brief left-side freezes while fully conscious, one occurring publicly at a Canon networking event and twice while driving, leading to her no longer being allowed to drive. They criticize the U.S. healthcare system, including receiving results via a CD and delayed medical follow-up, and note her surgery was expedited through her surgeon brother's connections. They use dark humor about naming the tumor “Tumi,” potential sketches, filmmaking memories, and plan a podcast pause until June while promoting getrealisms.com during recovery. Hosts: Adam Rani (@adamthechase) & Christine Chen (@cchenmtf) About Christine W Chen: Christine W. Chen is a Taiwanese American filmmaker, Academy member (Short Films Branch), and versatile producer, director, and writer known for bold, character-driven storytelling. Through her production company, Moth to Flame, she has created award-winning short films, features, and branded content—including Erzulie, a feminist swamp thriller that had a limited theatrical run and now streams on major platforms. In addition to her directorial work, Christine is a seasoned DGA 1st Assistant Director and co-author of Get Reelisms and ABCs of Filmmaking, as well as the co-host of the Get Reelisms Podcast. For more information about Christine Chen: christinewchen.com About Adam Rani: Adam Chase Rani is a production designer and set dresser working in the Austin film market, bringing a sharp eye for visual storytelling and practical creativity to every project. During the pandemic, he co-founded the Get Reelisms Podcast with Christine Chen to foster community within the film industry. Together, they've built a platform that blends education, candid conversations, and industry insights to help filmmakers connect, learn, and grow. WEBISODE version of the Podcast 00:00 Brain Tumor Reveal 00:22 Podcast Intro Setup 01:41 Mothers Day Message 02:06 Diagnosis And Surgery Date 03:58 Coping With Dark Humor 04:49 Seizure Symptoms Explained 10:06 Driving Scare And No Keys 11:58 Healthcare System Breakdown 13:03 The CD Player Sketch 16:34 Surgeon Mafia Fast Track 26:40 Friends Support System 27:58 Devil Wears Prada 2 Tangent 29:47 Bots And Bad Reviews 32:27 No Guest Just Us 33:25 Traveling Podcast Memories 34:07 Journaling Through Hard Times 36:04 Not Knowing and Learning 37:33 Cheap Gear Real Talk 38:28 Honest Film Podcast Philosophy 40:23 Fugitive Dreams War Stories 46:36 Family Pressure and Set Culture 51:45 Guest No Show Mothers Day 53:29 Gratitude and Friendship 57:06 Erzulie Set Highlights 01:00:09 Make A Wish Film Funding 01:03:25 Wrap Up and Merch Plug Official Get Reelisms PageGet Reelisms Amazon StoreInstagram
In Part 7 of the Varela Contemplative Science Retreat, Molly Crockett turns to a question with real stakes in the race of AI development: Can Buddhist ethics be taught to a machine? Drawing on Francisco Varela's concept of ethical know-how, she distinguishes “knowledge that” — facts and principles a system can represent — from “knowledge how,” the embodied wisdom that “requires embodied experience… Source
Antibiotics are not magic. In this episode of the PFC Podcast, Dennis sits down with Ryan to cut through the common myth that “I've given antibiotics, so the wound is protected.” They unpack why vigorous wound care—irrigation, debridement of dead tissue, clean dressings, and early surgical washout—remains the foundation of infection prevention in combat and prolonged field care, while antibiotics only shift the probabilities after the basics are done.Drawing on historical military medicine (pre-antibiotic eras through GWOT), observational data from the TIDOS study, sepsis timing principles, and real-world experience from Ukraine's prolonged timelines, Ryan explains why mortality is a limited endpoint, why more broad-spectrum antibiotics are not the answer in high-resistance environments, and how medics and corpsmen at the point of injury make the biggest difference.Key TakeawaysAntibiotics help only after good wound care; they never replace irrigation, debridement, and clean dressings.Dead or grossly contaminated tissue will not respond to antibiotics no matter how many doses you give.Mortality is a blunt and uncommon endpoint in modern combat trauma—look instead at reduced wound infections, osteomyelitis, reoperations, and amputations.Practical timing for prophylaxis: ideally within 1 hour, at least within 3 hours (extrapolated from sepsis data).Superficial wounds may need wound care alone; deeper or contaminated wounds benefit from antibiotics once cleaned.Shorter courses (roughly 3–5 days) are often sufficient in stable patients without established infection—stop when the benefit is exhausted.In prolonged or delayed-evacuation settings (Ukraine lessons), vigorous bedside wound care outperforms escalating antimicrobials amid rising resistance.Guidelines often assume basic wound care knowledge; that assumption may need to be made more explicit.The medic or corpsman at the point of injury is the decisive factor; higher-echelon care is supportive.Go to www.prolongedfieldcare.org for more austere and prolonged field care resources. Follow @prolonged_field_care on Instagram, subscribe on your preferred platform, and stay on the bleeding edge of combat medicine.Chapters00:00 – Intro & Disclaimer00:21 – Welcome and the Core Question: Do Antibiotics Actually Matter?01:18 – “Antibiotics Aren't Magic” – Historical Context and the Penicillin Era02:17 – What Antibiotics Actually Do (and Don't Do) in Infected Wounds03:14 – Wound Care Has the Bigger Impact04:00 – Pre-Antibiotic Military Medicine Lessons05:04 – Why Guidelines Don't Emphasize Wound Care Explicitly06:49 – Fungal Prophylaxis Debate and “Hot Lights and Cold Steel”09:02 – Combat Medicine as Its Own Specialty and the Loss of Institutional Memory13:17 – Why We Don't Have Clear Mortality Data on Prophylactic Antibiotics16:21 – What Antibiotics Actually Prevent (Complications, Not Early Death)18:48 – TIDOS Study, Observational Evidence, and Current Guidelines21:39 – Ukraine Lessons: Prolonged Care, Resistance, and Wound Care Priority24:31 – King for a Day: Would You Change Prehospital Teaching?27:42 – Timing of Antibiotics: 1-Hour Ideal, 3-Hour Reasonable Window30:03 – When Antibiotics Are (and Aren't) Needed – Superficial vs Deep Wounds32:29 – Withdrawing Antibiotics in the Field – Duration Principles34:16 – Final Thoughts: Wound Care First, Antibiotics Second
What if your gym pays you well but still isn't something a serious buyer wants to own? And what would have to change for your business to give your family real options—whether you keep it, scale it, or sell it?Episode ChaptersBlake and Sherman sit down with Jeff Smith, founder of Tactical Empire, to unpack what it really looks like to build something beyond a decent-paying owner job. Jeff walks through his path from college sports and enlisting after 9/11 to serving in special operations, returning to a Fortune 50 company, owning a gym for 12 years, and buying and selling around $25 million in real estate while raising four kids. That mix of experience shapes how he thinks about risk, time, and why sitting in “planning mode” for a decade is so costly.The three of them talk through leaving a mentoring organization, feeling like you're on an island, and the moment a serious buyer asked how often the owner needed to be at the gym—exposing that the business wasn't truly an asset. They also get into faith, mortality, homeschooling, full-time RV life, and the tension many gym owners feel between wanting to serve and wanting to earn at a high level. It's aimed at owners who care about their families and clients and also want a business that gives them choices: keep it, scale it, or walk away on their terms.You'll LearnHow a gym can pay the owner six figures and still not be something a serious buyer wants to acquire.Why Jeff's time in special operations and a Fortune 50 environment pushed him toward urgency instead of long-term “planning mode.”The difference between building yourself a job and building a business that can be run—and sold—without you on-site every day.What happens when a couple with real business experience asks, “How often do we have to be here?” before buying your gym.Why many owners only start thinking about exits once they're burned out, and how that limits their options.How asset sales (equipment and lease) differ from selling a business with systems, profit, and a clear valuation story.Why service-minded gym owners often hesitate to chase real money and how that mindset can undercut their families.How Jeff and his wife sold their house, moved into an RV with their four kids, and homeschooled while still building income and investments.A practical example of someone shifting from strict “no debt” thinking to using home equity more strategically once discipline and assets are in place.Episode Chapters01:05 Leaving the mentoring group and Jeff's support04:45 Why Tactical Empire exists and who it serves07:10 Gym owners, service businesses, and the mastermind10:15 Jeff's path: sports, 9/11 enlistment, special ops12:20 Corporate career, Six Sigma, and owning a gym15:00 Real estate deals and building multiple income streams18:30 Mortality, urgency, and not wasting a decade21:10 Homeschool dads, RV life, and family decisions24:20 From gym paycheck to “is this actually an asset?”27:05 Asset sale vs. business sale for gym owners30:00 Exit timelines, burnout, and planning 2–3 years out33:20 Debt, equity, and rethinking a paid-off houseAbout the GuestJeff Smith is the founder of Tactical Empire, where he works with male, service-based entrepreneurs through a men's mastermind and one-on-one consulting. His background includes college athletics, military service in special operations after 9/11, 18 years with a Fortune 50 company, long-term gym ownership, and extensive real estate investing. Facebook: https://www.facebook.com/jeff.smith.896413Instagram: @realjeffsmithAbout the PodcastGym Marketing Made Simple cuts through the noise around gym growth. Each episode focuses on practical marketing, sales, and leadership systems designed for boutique fitness gyms. The goal: clear messaging, better leads, and cleaner sales processes so owners can grow without guessing, chasing, or burning out their teams.Listen & Subscribe
Dr. Meyers talks with Laura Himmelstein, LCSW, for an intimate and reflective conversation about grief, caregiving, dementia, aging, caregiver burnout, cognitive decline, and mortality.Drawing from both her clinical work and personal experience caring for her mother through dementia, Laura shares the emotional complexity of witnessing cognitive decline, navigating caregiver exhaustion, and grieving someone before they are physically gone. Together, they explore anticipatory grief, the ambiguous nature of loss, the psychological impact of losing a parent, and how personal experiences with grief inevitably shape therapists and mental health professionals both personally and professionally.The conversation also examines countertransference, fears surrounding aging and cognitive decline, the emotional impact of caring for aging parents, and how our relationship to death changes over time. What happens when clinicians are forced to confront the very vulnerabilities they help others navigate every day?This episode is an honest discussion about love, anticipatory grief, caregiving, identity, grief counseling, end-of-life experiences, and the ways loss changes us — not only in how we grieve, but in how we live.
This podcast is made possible by our listeners and viewers. If this show has brought you value, you can support it by becoming a member of The Way Forward, our platform designed to help you find the health and freedom community (people, practitioners, schools, farms, and more) near you. Your membership directly supports the podcast and the work we do.Data centers and flock cameras are damaging our society in ways most people can't even imagine.My guest today is Clayton Tucker: Lampasas rancher, Secretary of the Texas Farmers Union, and candidate for Texas Agriculture Commissioner running to halt AI data center expansion statewide.Clayton lived in China and Taiwan and saw the surveillance playbook up close. That same playbook is getting imported here through hyperscale AI facilities, Flock cameras, and utility lines built by bureaucrats who may not even have the legal authority to route them.A cattle rancher north of Dallas lost calves to stillbirths after a BESS facility went in across the road. A mother and daughter watched migraines and ear infections stop the moment they moved away. A Canadian sheep farming family lost about 500 head, and the daughter told Clayton her father developed early-onset dementia in the same window.Clayton also lays out the counter-move: ag impact studies, development districts, water conservation districts, rezoning, cross-partisan pressure.If you eat food and live in Texas, this one's for you.You'll Learn:[0:00] Introduction[8:45] Why the 5,000-to-400 China gap makes the whole competition argument a lie[19:20] The Flock camera that appeared at his ranch after he started talking[28:05] Wall Street's plan to drain Texas dry, and the cooling scam that hides it[39:57] 765 lines corroding pipelines toward disaster, and the zero-water tech being ignored[55:49] The stillbirths, migraines, and dead sheep that nearby families report[1:28:19] Light pollution two miles out still wrecks your biology [1:37:51] The tax handouts fueling BESS fires, and why stopping the AI bubble matters now[1:59:33] The limits of fixing this alone, and Clayton's message to MAHA on change[2:09:49] The regenerative score label, and flagging processed food as abnormal[2:28:21] His MAHA-branded opponent's stock ties to glyphosate and TysonRelated The Way Forward Episodes:Coming Home: Healing the Chronic Disease of Separation with Dr. Zach Bush | PodcastEz-Water, Aether, & The Biofield featuring Carrie Bennett | PodcastCircadian Biology, Leptin, & Light featuring Sarah Kleiner | PodcastHow Too Much Artificial Light & Sunlight Affect Lifelong Health & Mortality with Matt Maruca | PodcastResources Mentioned:AI Data Center Map | WebsiteFamily Farms Filing Bankruptcy by Alec | Instagram PostFind more from Clayton:Clayton Tucker | Pitch In | Learn MoreFind more from Alec:Alec Zeck | Instagram | XThe Way Forward | InstagramDonate to The Way Forward here.The Way Forward is Sponsored By:New Biology Clinic: Redefine Health from the Ground UpExperience tailored terrain-based health services with consults, livestreams, movement classes, and more. Use code THEWAYFORWARD (case-sensitive) for $50 off activation.The Way Forward members get the $150 fee waived.BEAM Minerals: Feel the Difference in Days: Join thousands recharging with plant-based minerals. Click here for 20% Off Your First Bottle of BEAM.Want more crypto insights and a community to back you up?Join the Crypto Freedom Academy today. It's 100% free and designed to help you master the markets.
What keeps someone grinding when facing a terminal diagnosis? In this episode, Kevin shares a powerful morning jog with his 79-year-old biological father, who is currently battling Stage 4 cancer with a colostomy bag yet still hitting the pavement every day at 8:15 AM.Nole and Kevin dive deep into the uncomfortable but necessary reality of mortality, examining why people choose to lean in rather than check out, how lifelong habits shape our final seasons, and the profound peace found in faith, presence, and letting go of old grudges. To wrap things up, Nole recaps a family trip to Arizona featuring "trashy" tacos, javelinas, and coatimundi sightings, followed by details on the upcoming 9/11 Memorial Stair Climb.Big thank you to My Epic and Facedown Records for the use of their song "Hail" in our podcast!https://www.youtube.com/watch?v=Dz2RZThURTU&ab_channel=FacedownRecordsSign up for the stair climb!https://www.eventbrite.co.uk/e/6th-annual-911-memorial-climb-25th-anniversary-sponsored-by-stairmaster-tickets-1992947168630?aff=oddtdtcreator&keep_tld=trueThe Fire You Carry on YouTube.Sign up for a class at The Fire Up Program!https://www.fireupprogram.com/programsThe Fire Up Progam video.https://www.youtube.com/watch?v=I__ErPW46Ec&t=12s&ab_channel=FireUpProgramThe Fire You Carry Instagram.https://www.instagram.com/thefireyoucarry/Donate to The Fire Up Program.https://www.fireupprogram.com/donateThe Fire Up Program Instagram.https://www.instagram.com/fireup_program/Kevin's Instagram.https://www.instagram.com/kevinpwelsh/?hl=en
SELECTED SHORTS host Meg Wolitzer presents four works that were read as part of our live evening with WNYC's Radiolab and hosts Lulu Miller and Latif Nasser.The theme was flight in many imaginative manifestations. Randa Jarrar's “The Lunatics' Eclipse” is a fable-like story of romance and interstellar travel, read by Abubakr Ali. Our second story is “Roy Spivey,” by Miranda July, and is a sly and gentle probing of celebrity culture. It's read by Molly Bernard. Don Shea's “Jumper Down” bares the vulnerability and resilience of a rescue worker. it's read by Becca Blackwell. And our last story, “My Life as a Bat,” shares the secret life a mysterious creature in fact and fable. It's by Canadian fiction master Margaret Atwood and is read by Zach Grenier. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Randomized interventional trials are necessary to establish cause and effect.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Jim Otvos is a biophysical chemist who pioneered the use of nuclear magnetic resonance (NMR) spectroscopy to measure lipoprotein particles and developed the first FDA-cleared method for directly quantifying LDL particle number (LDL-P), a technology that has since expanded to provide broader insights into metabolic health, inflammation, insulin resistance, and mortality risk. In this episode, Jim recounts the unlikely story of transforming a flawed cancer test into a new way of measuring lipoproteins, explains what standard cholesterol tests can miss and why LDL-P and apoB can inform treatment decisions beyond LDL cholesterol alone, and dispels the misconception that large, "fluffy" LDL particles are benign. He also explores how NMR can reveal insulin resistance before blood sugar rises, GlycA as a marker of chronic low-grade inflammation, and the metabolic vulnerability index (MVX) as a potential measure of frailty, resilience, and mortality risk across the lifespan. Finally, Jim explains why NMR diagnostics remain underused despite the wealth of information they can extract from a single blood test. We discuss: How investigating a flawed 1986 cancer test led to the development of NMR (nuclear magnetic resonance) lipoprotein testing [3:30]; How standard lipid panels measure cholesterol and triglycerides, and why LDL cholesterol is estimated rather than directly measured [15:15]; How NMR spectroscopy measures lipoprotein particle size and concentration [20:30]; Why LDL particle number matters more than particle size, and why large, "fluffy" LDL is not benign [28:45]; Discordance between LDL cholesterol and LDL particle number: which measure better reflects cardiovascular risk? [36:30]; How metabolic syndrome and lipid-lowering treatment contribute to the discordance between LDL-C and LDL-P, and the value of particle number for managing risk [45:30]; Using the NMR-derived LP-IR score to detect insulin resistance and predict type 2 diabetes before glucose rises [51:15]; The development, commercialization, and uncertain future of the Vantera NMR Analyzer and NMR-based diagnostics [1:04:45]; The analytical efficiency of NMR testing and the data-driven development of the Metabolic Vulnerability Index (MVX) [1:16:00]; GlycA as an NMR-derived marker of systemic inflammation: its discovery, biological basis, and advantages over hs-CRP [1:25:45]; Developing the Metabolic Vulnerability Index (MVX): biomarkers of inflammation, malnutrition, muscle wasting, and mortality risk [1:34:00]; What MVX can tell us about longevity and mortality [1:44:15]; How MVX may reveal metabolic frailty and predict premature mortality decades in advance in young, healthy adults [1:50:30]; Potential applications of MVX for predicting treatment response, surgical resilience, and clinical trial outcomes, and the barriers to broader use [2:00:00]; ApoB versus LDL-P: their clinical similarities, the additional information provided by NMR, and barriers to broader adoption [2:07:30]; Interpreting the effects of the CETP inhibitor, obicetrapib, on LDL-P, apoB, and small HDL particles [2:13:00]; The future of NMR diagnostics and MVX: translating scientific potential into broader clinical use [2:20:45]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube