Podcasts about Psilocybin

In this revisited episode of The Observatory, while our hosts are globetrotting, Scott and LaRae share the transformative power of creativity, a fundamental aspect of human nature that enables self-discovery, emotional fulfillment, and the pursuit of meaning in life. Creativity is a universal capacity that allows us to express our authentic selves, connect with others, and find joy. Hear Brené Brown's perspective on creativity, how you can start to be creative, and how a bigger imagination prompts beautiful experiences.Timestamps[05:40] Brene Brown's perspective of creativity[07:00] Why are many humans not creative?[16:19] Having a bigger imagination that prompts beautiful experiences[18:34] The book: Mary Jane Wild by Brooke[22:43] Creating the internal landscape of you[23:21] Starting the journey to being creative[29:02] Where is your creativity showing up?[33:00] Allowing things to unfold naturally[39:34] The real meaning of abracadabra[44:51] Keep dreamingNotable quotes:“There is no such thing as creative people and non-creative people. There are only people who use their creativity and people who don't.” - Brene Brown [05:40]“The unused creativity stays inside of us because we are creating a life.” - LaRae Wright [21:48]“If you don't feel creative, this is a good place to start. Go into nature and observe.” - Scott Wright [22:54]“Open yourself up to the possibility that you don't have to know what you will do when you begin to do it. You are opening a space to allow yourself to create.” - Scott Wright [31:26]Relevant links:The book: The Gifts of ImperfectionThe book: Mary Jane WildSubscribe to the podcast: Apple Podcast

We're marking Rare Disease Month 2026 by highlighting the powerful story of Shanthi Hegde, a young patient advocate working to transform how bleeding disorders are understood, treated, and supported. This work is fueled by her own arduous journey with two rare bleeding disorders and immune dysregulatory syndrome, and an extended diagnostic odyssey marked by dismissal, underdiagnosis, and structural bias. “I was told many times by many providers that these disorders are not common in Indians and that my bruises were there just because I'm brown.” Admirably, Shanthi pushed past this mistreatment, advocated for her medical needs, and devoted herself to tackling a range of issues confronting rare disease patients from mental health access to affordable drug pricing to research equity. In this remarkable Year of the Zebra conversation with host Lindsey Smith, you'll also learn about: Shanti's work with the Hemophilia Federation of America; How gaps extend beyond treatment to include insurance coverage, provider training, and substance use care; What clinicians can do to improve the work they do with rare disease patients. Join us for a conversation that connects patient voice to system change, and explores what real equity for rare disease communities will require. Mentioned in this episode:Hemophilia Federation of AmericaShanthi's LinkedIn Profile If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

FINAL PRIVATE ROOM – THE GOD MODE RETREATFull retreat details:godmoderetreats.comSecure the final private room:jamesxander.com/1spotBook a discovery call (ask questions, confirm alignment, get help with logistics):jamesxander.com/applyIn one week, The God Mode Retreat begins.This is a five-day immersive container for deep inner work, clarity, connection, and identity-level transformation — designed for those navigating change, transition, or a quiet call toward something deeper in life.There is currently one private room remaining.If you feel resonance but have questions around timing, travel, finances, or readiness, book a discovery call and we'll explore alignment together.If you already know this is for you, you can secure the final private room directly.This isn't about pressure or urgency.It's simply an invitation to listen to your intuition and respond honestly to what feels aligned right now.With love,James ★ Support this podcast on Patreon ★

“I've never seen this type of healing in the conventional healthcare system. Never. It's so profound and so fast and long lasting, and it's just absolutely mind blowing every time. Not always, though, isn't this effective for everybody, right? It's not a magic pill or a cure all or anything like that. But for the people that it does work for, they say that everything they tried didn't work, but this was it.  It brings me to my soul work, which is being able to be a bridge or a facilitator, to help somebody heal, and that is what lights me up.” ~Anna Desmarais BSN, RN, HWNC-BCAh Ha MomentsIntegrative Nurse Coaching can reconnect you to your “why.”  It's OK to shift the way you show up and practice as a Nurse, connecting back to your purpose can help you discover new ways to find joy and a renewed passion for your work.Anna's biggest Integrative Nurse Coach Academy Nurse Coach Certificate Program takeaway: hold space, listen deeply, use silence well, and ease up on the “fix it” reflex.It's not all private practice. Her Integrative Nurse Coaching skills translate directly into nurse-led telehealth roles with ongoing client relationships, without constant hustle.Psilocybin highlights the evolving role of nursing. Integrative Nurse Coaching skills, like presence, safety, and deep listening, facilitate naturally into psilocybin-supported care, where Nurses can blend clinical expertise with holistic, relationship-centered healing.Your RN background becomes a superpower in all spaces. Nursing supports safety and clinical judgment, coaching supports preparation, regulation, and integration for real change.Links and ResourcesIntegrative Nurse Coaches in ACTION! podcastNursing Pathways in Psychedelic Care courseUpcoming (legal) psilocybin retreat in Boulder, CO in AprilThe Path Back: A Holistic Nurse's Guide to Healing from the Intersection of Science, Spirituality, and Ancient WisdomLink to a free consultation with AnnaINCs in ACTION! Podcast episodes related to psychedelics80: Psychedelics and Sacred Medicine in Nursing- Dr. Stephanie Van Hope DNP, RN, NC-BC69: Combining Psilocybin Education and Nurse Coaching- Chandra “CeeCee” Campanelli RN, HN-BC, HWNC-BC*****Thank you for listening. We LOVE Nurses!Please leave us a 5 Integrative Nurse Coach Academy I Integrative Nurse Coach FoundationWe provide nurses with a global community for learning, networking, and reconnecting. Thank you for listening. We LOVE Nurses! Please leave us a 5 star rating and a positive comment about an episode you love! Follow Integrative Nurse Coach Academy on Facebook, Instagram, LinkedIn Learn more about our programs at the Integrative Nurse Coach Academy Schedule a free call with one of our awesome admissions specialists here>> and get your questions answered! Use the code 'ACTION' at checkout and get $100 off the Integrative Nurse Coach Certificate Program (Parts 1 & 2 Bundle).

Psychedelics are having a cultural moment. Research is promising. Stories of healing are everywhere. But here's the truth: these experiences aren't magic cures. And they aren't right for every nervous system at every time.   In this episode, Elisabeth Kristof and Jennifer Wallace slow the conversation down. Instead of asking, "Do psychedelics heal trauma?" They explore a more grounded question: What becomes possible when psychedelic or peak somatic experiences are approached through the lens of nervous system safety, preparation, and integration?   If you've been curious about psychedelics, already had experiences, or feel unsure whether they're right for you, this episode offers nuance, research, and deep nervous system perspective. Because post-traumatic growth isn't about becoming someone new. It's about becoming more available to the life that's already waiting for you.   Topic Covered Why psychedelics may reorganize meaning, not just reduce symptoms How trauma fragments narrative and how safety allows integration The science of psychological flexibility and why it predicts long-term outcomes What "somatic journeying" is and why it can feel disorienting The importance of preparation, titration, and facilitator trust Why intensity does not equal healing Psychedelics vs antidepressants in research on connectedness Default Mode Network (DMN), identity rigidity, and belief updating Why creativity often emerges when survival softens The risks of over-reliance and "chasing the medicine" Why discernment and self-trust matter more than hype   Chapters  00:00 – Psychedelics Aren't Magic Cures
 03:00 – Meaning-Making & Narrative Reorganization
 08:58 – Psychological Flexibility & Emotional Capacity
 17:00 – Preparation, Somatic Journeying & Integration
 23:29 – Connectedness & Relational Repair
 34:33 – Identity, Neuro Tags & the Default Mode Network
 41:03 – Creativity as a Byproduct of Safety
 48:14 – Discernment, Industry Hype & Self-Trust   Calls to Action: Neurosomatic Intelligence is now enrolling : https://neurosomaticintelligence.com/nsi-certification Sacred Synapse: an educational YouTube channel founded by Jennifer Wallace that explores nervous system regulation, applied neuroscience, consciousness, and psychedelic preparation and integration through Neurosomatic Intelligence.    Wayfinder Journal: Track nervous system patterns and support preparation and integration through Neurosomatic Intelligence.   FREE 1 Year Supply of Vitamin D + 5 Travel Packs from Athletic Greens when you use my exclusive offer: https://www.drinkag1.com/rewired  Learn to work with Boundaries at the level of the body and nervous system at https://www.boundaryrewire.com Get a two-week free trial of neurosomatic training at https://rewiretrial.com Sources:    Amada, N., et al. "The Transformative Potential of Psychedelic Experiences: A Qualitative Analysis of Meaning-Making and Narrative Reorganization." Journal of Consciousness Studies, vol. 27, no. 7–8, 2020, pp. 122–150.   Carhart-Harris, Robin L., et al. "Neural Correlates of the Psychedelic State as Determined by fMRI Studies with Psilocybin." Proceedings of the National Academy of Sciences, vol. 109, no. 6, 2012, pp. 2138–2143.   Carhart-Harris, Robin L., et al. "The Entropic Brain: A Theory of Conscious States Informed by Neuroimaging Research with Psychedelic Drugs." Frontiers in Human Neuroscience, vol. 8, 2014, article 20.   Carhart-Harris, Robin L., et al. "Psilocybin with Psychological Support for Treatment-Resistant Depression: Six-Month Follow-Up." Psychopharmacology, vol. 235, no. 2, 2018, pp. 399–408.   Davis, Alan K., Roland R. Griffiths, and Frederick S. Barrett. "Psychological Flexibility Mediates the Relations between Acute Psychedelic Effects and Subjective Decreases in Depression and Anxiety." Journal of Contextual Behavioral Science, vol. 15, 2020, pp. 39–45.   Davis, Alan K., et al. "Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial." JAMA Psychiatry, vol. 78, no. 5, 2021, pp. 481–489.   Erritzoe, David, et al. "Effects of Psilocybin Therapy versus Escitalopram on Depression and Emotional Connectedness in Major Depressive Disorder." The New England Journal of Medicine, vol. 384, 2021, pp. 1402–1411.   Griffiths, Roland R., et al. "Psilocybin Produces Substantial and Sustained Decreases in Depression and Anxiety in Patients with Life-Threatening Cancer: A Randomized Double-Blind Trial." Journal of Psychopharmacology, vol. 30, no. 12, 2016, pp. 1181–1197.   MacLean, Katherine A., Matthew W. Johnson, and Roland R. Griffiths. "Mystical Experiences Occasioned by the Hallucinogen Psilocybin Lead to Increases in the Personality Domain of Openness." Journal of Psychopharmacology, vol. 25, no. 11, 2011, pp. 1453–1461.   Watts, Rosalind, et al. "Patients' Accounts of Increased 'Connectedness' and 'Acceptance' after Psilocybin for Treatment-Resistant Depression." Journal of Humanistic Psychology, vol. 57, no. 5, 2017, pp. 520–564.   Weiss, B., et al. "Associations between Naturalistic Psychedelic Use, Psychological Insight, and Changes in Social Connectedness and Personality." Frontiers in Psychology, vol. 12, 2021, article 667987. Disclaimer: Trauma Rewired podcast is intended to educate and inform but does not constitute medical, psychological or other professional advice or services. Always consult a qualified medical professional about your specific circumstances before making any decisions based on what you hear. We share our experiences, explore trauma, physical reactions, mental health and disease. If you become distressed by our content, please stop listening and seek professional support when needed. Do not continue to listen if the conversations are having a negative impact on your health and well-being. If you or someone you know is struggling with their mental health, or in mental health crisis and you are in the United States you can 988 Suicide and Crisis Lifeline.   If someone's life is in danger, immediately call 911.   We do our best to stay current in research, but older episodes are always available. We don't warrant or guarantee that this podcast contains complete, accurate or up-to-date information. It's very important to talk to a medical professional about your individual needs, as we aren't responsible for any actions you take based on the information you hear in this podcast.   We invite guests onto the podcast. Please note that we don't verify the accuracy of their statements. Our organization does not endorse third-party content and the views of our guests do not necessarily represent the views of our organization. We talk about general neuro-science and nervous system health, but you are unique. These are conversations for a wide audience. They are general recommendations and you are always advised to seek personal care for your unique outputs, trauma and needs.   We are not doctors or licensed medical professionals. We are certified neuro-somatic practitioners and nervous system health/embodiment coaches. We are not your doctor or medical professional and do not know you and your unique nervous system. This podcast is not a replacement for working with a professional. The BrainBased.com site and RewireTrial.com is a membership site for general nervous system health, somatic processing and stress processing. It is not a substitute for medical care or the appropriate solution for anyone in a mental health crisis.   Any examples mentioned in this podcast are for illustration purposes only. If they are based on real events, names have been changed to protect the identities of those involved.   We've done our best to ensure our podcast respects the intellectual property rights of others, however if you have an issue with our content, please let us know by emailing us at traumarewired@gmail.com. All rights in our content are reserved.

We explore the FDA's expansion of Wakix as the first non-scheduled treatment for pediatric cataplexy; a Taltz and Zepbound combo shows promise in skin clearance for patients with psoriasis and obesity; we also look at the frontier of mental health with synthetic psilocybin; there's phase 3 results from a potential new treatment for chronic inducible hives; and a long-acting HIV injection could be a game-changer for patients who struggle with the daily pill grind.  

In this episode of the Observatory Podcast, Scott and LaRae Wright sit down for a short, intimate conversation about prayer—not as a rule-bound ritual, but as a living practice shaped by words, intention, gratitude, and alignment. They unpack how prayer can evolve beyond fear-based asking, and why the language we use—internally and out loud—can land as either medicine or venom. If you've ever felt conflicted about prayer, spirituality, or how to “talk to the Divine,” this episode offers a grounded reframe you can actually use.Timestamps[00:00:18] Scott introduces the topic: prayer (and why this conversation may surprise you)[00:01:20] Setting the scene: a quiet Sunday afternoon, post–Valentine's Day reflections[00:04:39] Scott shares a moment from his men's group that sparked this episode[00:08:39] What prayer meant growing up: structure, habit, and fear-based “asking”[00:10:07] When prayer feels like a ritual—or a task—instead of communication[00:13:30] Reframing prayer: intention, energy, and how words shape experience[00:19:34] Gratitude as a shared frequency: how prayer can create resonance[00:20:58] Scott reads a prayer that shifted his relationship with “prayer language”[00:24:39] “Toxic positivity”: when words sound good but aren't aligned underneath[00:29:20] The line that hits: “no venom passes my lips” and why it matters[00:30:16] Venom as poison: what words can do once they're released[00:34:46] Emotional regulation, balance, and not getting stuck in heavy energy[00:39:05] Closing takeaway: your words are either venom or medicineNotable Quotes“It felt more like a ritual or maybe a task. Task that I had to do.” – Scott Wright [10:07]“Well, it creates a resonance like a song would. Those words create a resonance.” – LaRae Wright [19:48]“So no venom passes my lips and no destruction results from my speech.” – Scott Wright [21:50]“That venom is like poison. It's not retractable.” – Scott Wright [30:16]“Just everyone pay attention to your words. Pay attention to whether they are venom or medicine.” – Scott Wright [39:05]Relevant links:Subscribe to the podcast: Apple PodcastProduced by NC Productions

Send a textGene regulation through RNAs, the neurobiology of opioid addiction, and how psychedelics affect drug-seeking by modulating inflammation and plasticity. Not medical advice.TOPICS DISCUSSED:Gene regulation basics: DNA transcribes to RNAs, including non-coding types like microRNAs that inhibit mRNA translation into proteins, influencing up to 60% of the proteome.Non-coding RNAs in neuroplasticity: MicroRNAs and circular RNAs regulate synaptic changes, with activity-induced ones like miR-485-5p linked to rapid responses in drug cue memory and addiction reinforcement.Opioid addiction models: Rats self-administer heroin or fentanyl via levers, showing compulsive seeking; fentanyl's higher potency drives faster learning but similar long-term effects to heroin when doses are equated.Differences between opioids: Heroin and fentanyl both activate mu-opioid receptors for euphoria and dopamine release, but fentanyl lingers longer; no major behavioral differences in seeking once potency is matched.Psilocybin's effects on addiction: A single psilocybin dose post-abstinence reduces heroin-seeking in rats by dampening neuroinflammation in brain regions like the nucleus accumbens and prefrontal cortex.Brain Inflammation: Opioids induce pro-inflammatory changes via cytokines like IL-17A and pathways like TNF-alpha, leading to glial activation and blood-brain barrier leaks; psilocybin counters this.MicroRNA biomarkers: Blood microRNAs reflect gene expression patterns tied to disease states, with potential to predict opioid relapse risk, treatment response, or neonatal withdrawal severity non-invasively.Future research: Ongoing work links psilocybin's serotonin 2A activation to anti-inflammatory gene changes, plus human studies on microRNAs for personalized addiction treatments.ABOUT THE GUEST: Stephanie Daws, PhD is an associate professor at Temple University in the Center for Substance Abuse Research and Department of Neurosciences, where she researches mechanisms of drug-seeking behavior with a focus on opioids and psychedelics.RELATED EPISODE:M&M 2 | Psilocybin, LSD, Ketamine, InflamSupport the showHealth Products by M&M Partners: SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

Keegan Downer (Founder of mindfulMEDS) shares how he went from alcohol addiction and a near-suicidal breaking point, to recovery and to building one of Canada's most recognized microdosing education brands, and why psilocybin doesn't have to be "woo."  We also get super practical: What microdosing actually feels like day-to-day, why it can hit women differently (especially moms), how psilocybin compares to SSRIs (Selective Serotonin Reuptake Inhibitor) when it comes to emotional processing, and why "wine o'clock" culture is quietly keeping so many women stuck in a stress-and-numb cycle. Join my NEW private community at thelongherlife.com for ongoing protocols, live coaching, and deeper support. WE TALK ABOUT:  05:40 - Keegan's life collapse that led to addiction and the "rooftop moment"  07:45 - Rebuilding purpose after rehab and the anxiety attack that changed everything  09:10 - Why microdosing went from "nobody's talking about this" to mainstream fast  12:35 - The day-13 breakthrough and the microdosing study that launched his mission  19:30 - Why psilocybin and SSRIs create totally different emotional outcomes  23:20 - When microdosing feels "too strong" and how dose + setting change everything  28:40 - The dose reality check: "microdose" vs "creative dose" and why sensitivity matters  38:20 - Why women (especially moms) are the fastest-growing microdosing segment  41:05 - "Wine o'clock" culture, addiction masking, and the uncomfortable truth  44:00 - Brainbow: The saffron extract approach for mood, sleep, and nervous system support  57:10 - Where to learn more, the free microdosing guide, and weekly consults RESOURCES: Join my NEW private community at thelongherlife.com for ongoing protocols, live coaching, and deeper support. Join me in Costa Rica for Optimize Her, a 5-night luxury women's retreat with biohacking, yoga, healing rituals, and longevity workshops—only 2 spots left. Download the non-toxic baby registry guide to reduce toxic exposure and make confident, evidence-informed choices for your family—free. Mindful Meds website and Instagram Get The Mindful Meds Microdosing Guide here LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music  

Few issues have tested public trust in medicine as deeply as vaccines, and few individuals have influenced that dialogue more than Dr. Paul Offit, director of the Vaccine Education Center at the Children's Hospital of Philadelphia and a longtime member of the FDA's Vaccine Advisory Committee. In this timely and candid interview with Raise the Line host Lindsey Smith, Dr. Offit points to this year's severe flu season and a resurgence of measles as alarming proof points of how a changing federal perspective on vaccine policy is having a real impact on public health. “You'd like to think you can educate about the importance of vaccines, but I fear at this point the viruses themselves are doing the educating.” In this wide ranging discussion, Dr. Offit also addresses: The rigorous and painstaking process of developing vaccines, based on his experience co-inventing the rotavirus vaccine. Shifting levels of public trust in scientific organizations. Promising innovations in vaccine development. Don't miss this deeply-informed perspective on the interplay of science, policy, and public education, and his encouraging message to young clinicians about managing the current challenges in public health.  Mentioned in this episode: Vaccine Education Center at Children's Hospital of PhiladelphiaPerelman School of Medicine If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Louise Hecker, Associate Professor of Medicine at Baylor College of Medicine. Together, they dive into Louise's recent research exploring how psilocybin, the active compound in psychedelic mushrooms, may influence aging biology at the cellular and organismal level.Louise shares the story behind her curiosity about psilocybin, sparked by conversations with a friend and fueled by a lack of scientific answers. She explains how her team overcame regulatory hurdles to study the effects of psilocybin on human cells and aging mice. Their findings showed that psilocybin extended cellular lifespan and reduced hallmarks of aging, such as oxidative stress and DNA damage. In mice, regular dosing improved survival, reversed visible signs of aging, and affected organs beyond the brain.The conversation also covers the challenges of translating these findings into humans, the need for more research on dosing and safety, and the importance of funding in moving this field forward. Louise encourages listeners to stay curious, think beyond established paths, and keep an open mind as new questions and discoveries emerge in the science of aging.Guest-at-a-Glance

Bei unserem Partner Scalable Capital gibt's jetzt nicht nur das unserer Meinung nach beste Broker-Angebot in Deutschland. Ihr kriegt auch noch 25 € vom Scalable-ETF, wenn ihr ein neues Konto eröffnet und nutzt. Dazu unterstützt ihr auch noch diesen Podcast. Mehr Infos gibt's hier. Aktivisten stürmen die Börsen: Elliott x Norwegian Cruise Lines, Starboard x TripAdvisor, Jana x Fiserv. Infleqtion-IPO, Raspberry Pi als KI-Geheimtipp, Compass Pathways mit Psilocybin. Warner Bros. x Paramount, Masimo x Danaher. ServiceNow x Management. Hat Bayer (WKN: BAY001) gestern die Lösung der Glyphosat-Krise gefunden? Und wieso steigt die Aktie immer weiter? Wir klären auf. Das ganze Interview mit Bill Anderson zum Bayer-Turnaround findet ihr hier: https://www.youtube.com/watch?v=tAxTJCDPQ08. Diesen Podcast vom 18.02.2026, 3:00 Uhr stellt dir die Podstars GmbH (Noah Leidinger) zur Verfügung.

Good morning from Pharma Daily: the podcast that brings you the most important developments in the pharmaceutical and biotech world. Today, we delve into a series of breakthroughs and strategic maneuvers that are reshaping the landscape of this dynamic industry.Roche is making waves with its antibody Gazyva, initially recognized for cancer treatment. The company has successfully ventured into autoimmune diseases, targeting kidney conditions. Recent phase 3 trials have reinforced Gazyva's efficacy in treating immune-mediated kidney diseases, building on its prior approval for lupus nephritis. This marks a potential paradigm shift from oncology to autoimmune therapy applications, offering a promising new avenue for treating complex kidney disorders. Such advancements underscore the power of immune modulation in addressing severe health conditions.Turning to oncology, Eli Lilly is expanding the use of its cancer drug, Retevmo. Originally approved for specific lung and thyroid cancers with rare biomarkers, Lilly is now exploring its use in the adjuvant setting for non-small cell lung cancer. This effort reflects a broader trend in oncology: companies are increasingly looking to extend the application of targeted therapies beyond their initial indications. This expansion could significantly enhance treatment options and improve patient outcomes.In ophthalmology, Ocular Therapeutix is preparing for an FDA filing following positive phase 3 results for its wet age-related macular degeneration treatment. Their candidate, AXPAXLI, showed superior efficacy compared to Regeneron's Eylea in head-to-head trials. Despite investor skepticism, Ocular remains confident in its product's potential to impact retinal disease management positively. The competitive landscape in ophthalmology is fierce, and innovative treatments with substantial clinical benefits over existing therapies can redefine standards of care.Eli Lilly is also strategically stockpiling Orforglipron, its oral GLP-1 candidate, in anticipation of FDA approval for obesity treatment. This proactive measure aims to prevent supply chain issues seen during previous GLP-1 launches. It reflects an industry-wide focus on ensuring product availability at launch to meet growing market demand effectively.On the regulatory front, there are significant shifts as well. The Trump administration's renewed pilot of 340B rebates aims to optimize drug pricing frameworks. Novartis has secured a long-term supply agreement with Niowave for Actinium-225 (Ac-225), crucial for developing targeted cancer therapies. This highlights the sustained demand for radiopharmaceutical isotopes as part of precision medicine initiatives.Biopharma funding is expected to recover steadily by 2026, albeit with a cautious approach favoring de-risked assets over broader platform technologies. Venture capitalists prefer predictable returns amidst an evolving market landscape.Now, let's turn to Japan, where Innovacell is planning a $92 million IPO on the Tokyo Stock Exchange. This move signals a renewed interest in biotech within the region after a long drought in IPOs. Financial strategies like these are vital for advancing cell therapies that hold promise for treating conditions once deemed challenging.Gilead Sciences has acquired synthetic lethal therapy from Genhouse Bio through a $1.5 billion deal, further underscoring the growing interest in synthetic lethality as a novel cancer treatment approach. This strategy focuses on targeting tumors while sparing normal cells, offering more effective therapies with fewer side effects.In mental health innovations, Compass Pathways has reported positive results from its pivotal trial using psilocybin for treatment-resistant depression. The success of this phase 3 trial highlights the potential role of psychedelics in psychiatric care and could revolutionize mental health treatments by providing new options Support the show

Last week, the FDA declined to review Moderna's mRNA-based flu vaccine, with Center for Biologics Evaluation and Research Director Vinay Prasad himself signing the refuse-to-file (RTF) letter. Prasad said Moderna's comparator group “does notreflect the best-available standard of care,” while Moderna pushed back, saying CBER had previously found a standard-dose flu shot to be an “acceptable” comparator. Despite the shocking turn of events, HHS backed Prasad, saying Moderna didn't “follow very clear FDA guidance from 2024.”Regardless of the reasons, the development imperilsModerna's breakeven plans, affecting not just the company's investigational flu vaccine but also a flu-COVID combo shot and other parts of the company's pipeline. And for the broader industry, it highlights the regulatory uncertainty that persists into 2026, even as other countries move full speed ahead with novel modalities.That regulatory uncertainty extended this week to DiscMedicine, whose rare disease drug bitopertin was rejectedby the FDA. The company tried to convince investors that its planned Phase 3 trial would pave the way toward a refiling, but analysts raised concerns that the study was developed with oldFDA leadership. Disc's situation also raises questions about the FDA's Commissioner's National Priority Voucher, which bitopertin had received.Meanwhile, Compass Pathways dropped long-awaited data from two Phase 3 trials of its psilocybin-based COMP360, showing strong durability data that “clearly met the Street's bar for success,” according to Stifel analysts. The company plans to complete a rolling new drug application by the end of the year.Finally, the CDC has been left leaderless, again, with the departure of Jim O'Neill, who had been servingas acting director after the ouster of Susan Monarez last summer. And Sanofi's Paul Hudson was removed as CEO last week. He'll be replaced by Merck KGaA's Belén Garijo, who becomes just the second woman in charge of a Big pharmacompany.

In Oregon and Colorado, you can book an appointment for psilocybin therapy, where a licensed therapist takes you on a guided trip using the drug that makes “magic” mushrooms hallucinogenic.Under federal law, psilocybin is illegal. But within the past few years, both states greenlit the drug for supervised medical use, and New Mexico may soon follow. It's being used to treat certain conditions, including drug-resistant depression and PTSD. With a lot more people taking the drug under state supervision, what are we learning about its safety and efficacy? Who is taking it, and can clinics make money?Host Flora Lichtman checks in on the state of these programs with Colorado Public Radio journalist Alejandro Galva. Then, she sits down with geriatric and palliative care specialist Stacy Fischer for a research update on the therapeutic use of the drug, and the nation's largest clinical trial for psilocybin use for advanced cancer patients facing mental health challenges.Guests:Alejandro Galva is the afternoon editor at Colorado Public Radio. He's also the editor of their series “The Trip,” which covers the psychedelic therapy landscape in the state.Dr. Stacy Fischer is a geriatric and palliative care specialist at UCHealth University of Colorado Hospital.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

120. Microdosing for Midlife: Hormones, Perception, and Libido (Week 3)Exploring how menopause, perception shifts, and nervous system regulation intersect with midlife libido.Episode SummaryThis episode continues Week 3 of Microdosing for Midlife, April Pride's 12-part audio companion to her Substack series exploring microdosing through the lens of midlife transition.In this conversation, April examines one of the most quietly asked questions among women in perimenopause and menopause: can microdosing influence hormones or libido? Rather than positioning psilocybin as a hormonal intervention, she reframes the inquiry around perception, serotonin signaling, emotional regulation, and nervous system safety.The episode explores how estrogen fluctuations affect mood stability, why cortisol and stress patterns shape desire, and how subtle perceptual shifts—rather than dramatic sensations—may influence connection and intimacy. Through personal reflection and grounded science, April centers integration over hype.

In this episode we are joined by Dr. Sameet Kumar, a clinical psychologist and researcher, for a wide ranging conversation on how we relate to death, grief and love- both individually and collectively.We explore Dr. Kumar's work on a clinical study using psilocybin with late-stage cancer patients, and what this research reveals about fear, meaning, and psychological suffering at the end of life. We also discuss, grieving mindfully, the difference between individual and collective grief, how modern society sequesters death away from our lives and the cost of that separation.This discussion is not about quick fixes or spiritual platitudes but an honest examination of how human beings, connect, suffer and grow from loss.

Join us in this powerful episode of the Max After Burner Podcast, hosted by Theresa Noach, the Ceremony Facilitator for No Fallen Heroes and Sacred Warrior Fellowship. In this inspiring conversation, we welcome Jodi Lemons, the founder of Last Call Ranch and Retreat. After a devastating training injury, Jodi faced the challenging loss of her identity, leading to a long battle with depression and PTSD. With a proud military background, Jodi served in the Air Force and as a first responder before continuing her service in the Army. Following a traumatic incident involving her son, Jodi sought help beyond the traditional VA system. After a decade of being medicated and denied alternative treatments, her journey of healing took a turn when she discovered No Fallen Heroes. Funded to explore ibogaine therapy, Jodi began to reconnect with her faith and rediscover the transformative power of creation through entheogenic sacraments. Tune in to hear Jodi's remarkable story of resilience and the path to reclaiming her life.No Fallen Heroes, Sacred Warrior Fellowship, Jodi Lemons, Last Call Ranch and Retreat, depression, PTSD, military, Air Force, first responder, ibogaine therapy, healing, entheogenic sacraments, faith, resilience. Instagram: @sacredWarrior Fellowship @nofallenheroes @theresaanoach

In this episode of the Observatory Podcast, Stephen Karafiath steps into the interviewer role alongside LaRae Wright to turn the conversation toward host Scott Wright himself. What unfolds is an honest and expansive discussion about Scott's personal awakening, the evolution of his relationships, and the inner work required to live life from the inside out.Scott reflects on pivotal life experiences that reshaped how he views identity, connection, and spiritual growth. Together, they explore vulnerability, shadow work, emotional responsibility, and the courage it takes to dismantle old belief systems while building a deeper sense of authenticity. This episode offers listeners a rare look behind the microphone as Scott shares his own story — not as a teacher, but as someone continually learning, questioning, and growing.Timestamps[00:00:03] Welcome to The Observatory Podcast[00:00:18] Stephen Karafiath introduces the idea of interviewing Scott Wright[00:01:12] Why turning the lens inward feels different[00:03:40] Scott reflects on early identity and personal shifts[00:08:22] Awakening moments that changed his trajectory[00:15:06] Navigating relationships through transformation[00:21:55] Vulnerability and emotional honesty as a practice[00:29:14] Letting go of certainty and embracing curiosity[00:37:45] The cost of authenticity and redefining success[00:48:30] Shadow work and self-accountability[00:59:11] Building emotional resilience through discomfort[01:10:44] Partnership, growth, and relational evolution[01:22:05] What it means to live from the inside out[01:33:50] Integration — how Scott applies these lessons daily[01:44:12] Reflections on hosting the Observatory PodcastNotable Quotes“Sometimes the hardest thing is realizing you don't have to defend the version of yourself you used to be.” – Scott Wright [29:14]“The work isn't about becoming someone new — it's about remembering who you've always been underneath the noise.” – Scott Wright [37:45]“When we stop trying to control how others see us, that's where real freedom begins.” – Scott Wright [48:30]“You can't bypass the shadow… you have to sit with it long enough to understand what it's asking from you.” – Stephen Karafiath [59:11]“Living from the inside out means you're willing to let your life look different than you imagined.” – LaRae Wright [01:22:05]Relevant links:Earlier episode with Stephen can be found here.Subscribe to the podcast: Apple PodcastProduced by NC Productions

“I do not believe we should be testing to test. We have to know, is this test going to change management and is it going to make a difference,” says pediatric allergist-immunologist Dr. Zachary Rubin. His knack for providing that sort of straightforward guidance explains why Dr. Rubin has become a trusted voice on allergies, asthma, and vaccines for his millions of followers on social media platforms. It's also why we couldn't ask for a better guide for our discussion on the rise in allergies, asthma, and immune-related conditions in children, and how families can navigate the quickly evolving science and rampant misinformation in the space. On this episode of Raise the Line, we also preview Dr. Rubin's new book, All About Allergies, in which he breaks down dozens of conditions and diseases, offering clear explanations and practical treatment options for families. Join host Lindsey Smith for this super informative conversation in which Dr. Rubin shares his thoughts on a wide range of topics including: What's behind the rise in allergic and immune-related conditions.Tips for managing misinformation, myths and misunderstandings. How digital platforms can be leveraged to strengthen public health.How to build back public trust in medicine.Mentioned in this episode:All About Allergies bookBench to Bedside PodcastInstagramTikTokYouTube Channel If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

What does it really look like to hold space for someone in their most vulnerable moments? Heather Shelton, nurse-turned-herbalist and psilocybin facilitator, shares her journey from medical trauma to healing work with nervous system herbs and plant medicine.Learn about lemon balm, motherwort, and chamomile for everyday support, what happens in a psilocybin session, and why plants have been her greatest teachers. Grounded wisdom for anyone called to healing work.What's in this episode:From medical trauma to herbalism and facilitation workLearning directly from plants when teachers weren't availableWhat a psilocybin session is really likeNervous system support: lemon balm, motherwort, and chamomileCreating safety and presence as a healerTeaching kids to trust their intuitionFor full show notes head HEREWant to learn from Heather and become the kind of herbalist people trust guide them in their healing journey? The Community Herbalist Certification & Mentorship Program teaches you how to think like an herbalist, hold space for real healing, and show up wiLike the show? Got a Q? Shoot us a Text!Now more than ever, we need an herbalist in every homeSo we're having an Herbalism Is Resistance Sale where you can get get 50% off our foundational herb program, Naturally Healed - Herbal Remedies for the Whole FamilyUse code RESISTANCE at checkout here Wondering how you can use your herbal skills to help people when times are tough?Grab Medicine For The People - An Herbalist's Guide To Showing Up For Your Community In Times of NeedIt's loaded with ideas and resources to help you help others!

What happens when a 20 year mental health veteran has her own existential crisis then undergoes her own psychedelic therapy? In Inna Zelikman's case, it completely transformed how she practices medicine.Inna Zelikman, RN, MS, ANP, PMH-NP, is the Director of Integrative Mental Health at Recovery Without Walls and a MAPS certified MDMA practitioner. Five years ago, her own psychedelic healing journey changed everything about how she sees and treats patients. Now she's challenging the cookie cutter protocols that dominate our field in favor of what she calls an "organic" approach to treatment.In this conversation, Inna shares her comprehensive patient assessment strategies, the medication categories that secretly block healing (even though they're not contraindications), and why some patients have profound psychedelic experiences but can still struggle.From consulting with psilocybin centers in Oregon to treating ketamine addiction, Inna offers a nuanced perspective on the complexities of psychedelic medicine and why proper preparation, support, and integration actually matter for lasting results.What You'll Learn:

Send us a textThe brain's mysterious claustrum region, its role in cognitive flexibility, and how substances like alcohol and psychedelics affect neural circuits and behavior. Not medical advice.TOPICS DISCUSSED:Cerebral cortex structure: Described as a six-layered structure with pyramidal neurons and inhibitory interneurons; information flows between layers and regions to process sensory input and enable complex behaviors.Claustrum anatomy & connectivity: A sheet-like subcortical structure embedded in white matter, bidirectionally connected to cortical areas, especially prefrontal regions in rodents, with broader connections in primates and humans suggesting an integrative role.Claustrum function in cognition: Experiments show claustrum activation during task switches from easy to demanding modes, synchronizing cortical networks via inhibition and rebound excitation, potentially enabling flexible behavior.Mouse models in neuroscience: Mice are used for genetic tractability to manipulate and monitor specific circuits, revealing claustrum's role in vigilance tasks but not simple ones.Alcohol's effects on brain circuits: Chronic alcohol promotes inflexible behaviors by altering striatal interneurons and inhibitory inputs, leading to compulsive drinking despite aversive consequences.Psychedelics & brain networks: Psilocybin disrupts default mode and other networks, inhibits claustrum via serotonin 1B receptors, with effects persisting 24 hours, possibly contributing to therapeutic benefits.Evolution of claustrum: Connectivity expands from rodents to humans, shifting from cognitive-specific to broader network control, including anti-correlated states like default mode versus task-engaged.Integration of claustrum & basal ganglia: Claustrum funnels prefrontal signals to basal ganglia for action selection; alcohol may impair this, exacerbating inflexibility in addiction.ABOUT THE GUEST: Brian, PhD is a professor in the Department of Pharmacology and Physiology at the University of Maryland School of Medicine, where he leads a neuroscience lab studying brain circuits underlying flexible and inflexible behaviors using mouse models, with a focus on alcohol use disorder.Support the showHealth Products by M&M Partners: SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

Imagine being afraid of a pickle. Or a banana. Or a nub of bread. That’s daily life for people with ARFID (Avoidant/Restrictive Food Intake Disorder). It's an eating disorder not driven by weight or body image, but by fear, sensory overwhelm, or low appetite. People with this condition experience real terror and powerful aversions to certain foods - far beyond picky eating. Clinical psychologist Dr. Evelyna Kambanis explains ARFID, who it affects, and how treatment helps people reclaim their lives. Andrew Luber (aka “ARFID Andrew”) shares his funny, blunt, and vulnerable attempts at food exposures online. And Danielle Meinert tells the story of carrying ARFID since toddlerhood, and the startling change she says came after a high-dose psilocybin experience. Resources: National Eating Disorders Association - ARFIDAssociation of Anorexia Nervosa and Associated DisordersFamilies Empowered and Supporting Treatment of Eating Disorders Suggested episodes: The hidden hunger of Pica: Stories from people who eat objects Anorexia is complex. Two people talk frankly about their decades-long journeys GUESTS: Dr. Evelyna Kambanis: Licensed clinical psychologist in the Eating Disorders Clinical & Research Program at Massachusetts General Hospital and a faculty member at Harvard Medical School. She is involved in clinical care and research on ARFID Andrew Luber, aka ARFID Andrew: Los Angeles filmmaker and social media creator who documents food exposures with humor under the tagline, “Conquering my fear of food one laugh at a time” Danielle Meinert: Lived with ARFID for 27 years after a major shift in her relationship with food following ear surgery as a toddler. After years of trying traditional approaches, she described experiencing a dramatic change after a session using psilocybin Support the show: https://www.wnpr.org/donateSee omnystudio.com/listener for privacy information.

Check out BeerBiceps SkillHouse's YouTube 1O1 Course - https://youtube.beerbicepsskillhouse.in/youtube-101Share your guest suggestions hereMail - connect@beerbiceps.comLink - https://forms.gle/aoMHY9EE3Cg3Tqdx9For all BeerBiceps vlog content Watch Life Of BeerBiceps - https://www.youtube.com/@LifeOfBeerBicepsBeerBiceps SkillHouse को Social Media पर Follow करे :-YouTube : https://www.youtube.com/channel/UC2-Y36TqZ5MH6N1cWpmsBRQ Instagram : https://www.instagram.com/beerbiceps_skillhouseWebsite : https://beerbicepsskillhouse.inFor any other queries EMAIL: support@beerbicepsskillhouse.comIn case of any payment-related issues, kindly write to support@tagmango.comUse my referral code RANVEER to get 1 week of free premium accessDr. Alok Kanojia जी को Social Media पे Follow कीजिए :-YouTube : https://www.youtube.com/@UClHVl2N3jPEbkNJVx-ItQIQ Instagram : https://www.instagram.com/healthygamer_gg/X : https://x.com/dr_alokkanojia?lang=enWebsite : https://www.healthygamer.gg/In this 462nd episode of The Ranveer Show, we are joined by Dr. Alok Kanojia (Dr. K), a Harvard-trained psychiatrist and a former monk, who bridges the gap between modern medical science and ancient Eastern wisdom. This episode takes you deep into the science of Kundalini, the biology of spiritual experiences, and the intersection of mental health and meditation.In this conversation with Dr. K, we talk about the neuroscience behind Chakras, the risks and benefits of Kundalini practices, and how substances like DMT and Psilocybin affect the brain compared to natural meditation. We also explore the concept of the Default Mode Network, the role of Serotonin and Dopamine in happiness, and practical ways to manage ego, narcissism, and confidence. This episode also covers the physiology of specific Chakras (from Muladhara to Ajna), the science of Anandamide (the bliss molecule), the existence of Asuras and Deities, and actionable techniques like Trataka (candle gazing). This podcast is a valuable resource for anyone interested in Psychology, Neuroscience, Mental Health, Spiritual Growth, and understanding the scientific validity of ancient Sanatan Dharma practices.(00:00) – Start of the episode(03:30) – Becoming a Monk at 21(07:26) – Harvard Psychiatry vs. Ancient Wisdom(14:56) – Does Meditation Cure Mental Illness?(19:32) – Kundalini & Enlightenment Explained(23:21) – The Biology of Your Chakras(32:22) – DMT, Ayahuasca & The Brain(38:22) – Serotonin vs. Dopamine: The Science of Peace(47:13) – Why We Are Getting More Depressed(54:13) – Scientific Reason for "Celibacy" Postures(1:02:37) – Why Kundalini Yoga Can Be Dangerous(1:09:38) – The Power of Guru Diksha (Initiation)(1:16:58) – Can Meditation Cause Psychosis?(1:25:07) – Default Mode Network: The Science of Ego(1:31:28) – Narcissism vs.True Confidence(1:38:37) – Observing The "Self"(1:46:37) – Coma Patient Who Lived a Whole Life(1:56:31) – Evidence of Past Lives?(2:03:04) – Confidence is Your Baseline State(2:07:53) – The Truth About Marijuana & Anandamide(2:17:44) – Stop Using "Toxic Fuel" for Success(2:23:53) – How to Work 7 Days Without Burnout(2:36:34) – Happiness Without External Substances(2:39:42) – Meeting Entities on DMT(2:46:51) – Asuras, Demons & The Subjective World(2:57:44) – Do Gods Care About Us?(3:09:11) – Trataka: A Safe Third Eye Practice(3:16:16) - End of the episode

In this episode of the Observatory Podcast, Scott and LaRae Wright sit down with Nathan Chase Plummer and Zaid Plummer to explore the story behind Guardian Mansion — a bold cross-country move, a historic restoration, and a shared vision rooted in partnership, creativity, and purpose.Together, they reflect on how a simple dream of restoring historic spaces evolved into a life-changing journey. Nate and Zaid share how they discovered the Kentucky property, what it felt like stepping into the mansion for the first time, and how the process of renovation mirrors deeper themes of identity, resilience, and co-creation. This episode dives into the emotional realities behind chasing big dreams — the hard days, the unexpected beauty, and the profound connection that comes from building something meaningful together.Timestamps:[00:00:18] Introducing Nate and Zaid Plummer and the story of Guardian Mansion[00:01:05] Early dreams of restoration and historic properties[00:05:17] First conversations about buying and restoring old buildings[00:09:51] Working through challenges together and trusting the vision[00:12:54] Discovering historic architecture styles and the “Second Empire” home[00:15:54] Traveling to Kentucky and arriving at the Bluegrass region[00:17:43] Turning into the driveway — the first emotional moment seeing the mansion[00:26:40] The deeper meaning behind restoring a historic space[00:38:15] Creative vision, storytelling, and preserving history[00:52:20] The realities of renovation and learning as you go[01:04:30] What Guardian Mansion represents todayNoteable Quotes:“I would love to buy it and renovate it and restore it.” – Nate Plummer [05:17]“The houses we were drawn to were the antebellums or the Greek revivals — like this house, a second empire.” – Nate Plummer [12:54]“Sometimes we have really hard days. But, we work.” – Zaid Plummer [10:08]“We flew into Lexington airport where my family for years had lived and done the horse business.” – Nate Plummer [16:03]“A dream together...” – Zaid Plummer [01:14:43]Relevant links:Follow the adventure here: Guardian Mansion YouTube: https://www.youtube.com/@GuardianMansionGuardian Mansion Instagram: https://www.instagram.com/guardianmansion/Also, listen to Nate's story;  coming out at 30, business & authorship, meeting Zaid — the big wedding, and manifestation of the Guardian: here! Subscribe to the podcast: Apple PodcastProduced by NC Productions

Send us a textPharmacology & neurobiology of psychedelics & MDMA, focusing on isomers, sex-specific effects, and mechanisms in animal models. Not medical advice.TOPICS DISCUSSED:Biased agonism: Different drugs activate the same receptor (e.g., 5-HT2A) but trigger varied intracellular pathways, explaining why LSD is psychedelic while similar lisuride is not.Enantiomers & isomers: Mirror-image versions of drugs like MDMA (S and R forms) and LSD (four isomers) often produce distinct effects; only one LSD isomer is psychedelic, for example.MDMA isomer effects: S-MDMA induces stronger head twitches (psychedelic proxy) via serotonin release, and increases dendritic spines in male mice but not females; R-MDMA has somewhat different effects.Sex-specific drug responses: In mice, females show stronger psychedelic effects (head twitches) from psilocybin and DOI at the same dose, but males exhibit greater post-acute benefits like reduced opioid withdrawal.Psilocybin in opioid addiction models: A single dose reduces place preference for oxycodone and withdrawal symptoms in male mice more than females, with opposite spine density effects in reward-related brain areas.Mechanisms beyond 5-HT2A: Psychedelics involve other receptors like metabotropic glutamate receptors, forming dimers with 5-HT2A to enable dual signaling pathways; effects in subcortical regions like nucleus accumbens are 5-HT2A-independent.Clinical implications: Street MDMA may vary in S/R ratios, affecting experiences; clinical trials often use racemic mixtures without weight-adjusted dosing, potentially missing sex differences.ABOUT THE GUEST: Javier Gonzalez-Maeso, PhD is a professor of pharmacology and toxicology at Virginia Commonwealth University, with a PhD in medicine from Spain focused on G-protein coupled receptors and human brain studies in depression and addiction.RELATED EPISODE:M&M 230 | Psilocybin & MDMA: Inflammation, Stress & Brain-Body Communication | Michael WheelerSupport the showHealth Products by M&M Partners: SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off. Lumen device: Optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

Dr. McFillin was a guest on the popular Health Ranger Report. This is the full interview. He was joined by Tracy Thurman-a person of faith until a cardiologist—not a psychiatrist—put her on Prozac for "energy." Within weeks, her connection to God vanished. She became a materialist atheist for seven years. In this episode, Tracy and Dr. McFillin expose what they call the psychiatric industrial complex's "spiritual weapon of war"—and why these drugs are designed to make you feel dead inside and that experience is measured as "working". A fascinating episode featuring a topic rarely discussed. 

Send us a textWhat happens when modern neuroscience, ancient plant medicine, and spiritual self-awareness collide?In this powerful conversation, Joey Pinz sits down with Dr. Leah Linder—naturopathic physician, reverend, and co-founder of Setas Seminary—to explore how psilocybin mushrooms are being used responsibly, ethically, and intentionally to support healing from trauma, PTSD, anxiety, addiction, and cognitive decline.Leah breaks down the actual science behind psilocybin—how it reduces neuroinflammation, stimulates brain-derived neurotrophic factor (BDNF), and helps the brain form new neural pathways—while also explaining why integration and nervous system regulation matter far more than the ceremony itself.You'll also hear why psilocybin became a Schedule I substance, how federal religious protections allow safe access today, and why healing isn't about being “fixed,” but about learning to listen to your body and rewrite old stories.This episode is grounded, thoughtful, and eye-opening—perfect for anyone curious about the future of mental wellness, consciousness, and sustainable personal growth. 

The first healing centers to offer therapy using psychedelics are open in Colorado and they've been a longtime coming. They're meant to treat things like PTSD and depression. For our series, The Trip: CPR's Coverage of Colorado's Psychedelic Journey, Denverite's Kiara DeMare visited some of these new facilities. Then, state lawmakers will consider a bill today with the goal of reducing domestic violence fatalities. Plus, still trying to make good on that New Year's Resolution to kick that tobacco habit? The good news is that there's free help available and an extra incentive through Colorado Quitline. And we "Raise the Curtain" with theatre critic John Moore of the Denver Gazette who shares highlights of the recent True West Awards and the healing power of theatre and storytelling. 

Join host Theresa Noach as she sits down with Mike Smith, the visionary founder and head alchemist of Alchemist Farms. In this heartfelt episode, Mike opens up about his transformative experience during a ceremony led by Theresa through the Sacred Warrior Fellowship. He shares how profoundly impactful that journey was for him.With years of expertise in the realm of medicinal plants, Mike provides valuable insights into the benefits of microdosing psilocybin. Discover how this practice can facilitate a deeper connection with Spirit and promote inner healing. Alongside personal anecdotes, Mike also highlights crucial scientific facts about psilocybin's effects.Tune in to learn about the fascinating ways psilocybin can foster the creation of new neural pathways in the brain when used thoughtfully. Don't miss this enlightening conversation that blends personal experience with scientific understanding!

In this episode of the Observatory Podcast, Scott and LaRae Wright sit down with Stephen Karafiath and Carrie Cox, two friends in a new relationship who are intentionally building love through secure attachment, emotional honesty, and nervous-system awareness.Together, they explore what it means to “wade through the muck” instead of bypassing discomfort — how trauma can be alchemized, how boundaries create safety, and how a shared relational container allows for co-regulation, depth, and intimacy. This conversation touches on vulnerability, conscious partnership, and the courage required to stay present when things get messy — because that's often where transformation lives. Timestamps[00:00:18] Scott and LaRae introduce Stephen Karafiath and Carrie Cox[00:01:03] A new relationship built on depth, presence, and intention[00:02:45] Referencing the Safe to Love podcast conversation[00:03:44] Growth, humility, and learning to soften[00:04:42] Experiencing secure attachment for the first time[00:06:25] Vulnerability, grief, and emotional safety[00:09:22] Metasound, play, and relational witnessing[00:10:31] Water rituals and nature as grounding allies[00:12:46] “Wading through the muck” and where alchemy happens[00:26:02] Alchemizing inherited shame and childhood beliefs[00:26:21] Letting water and nature help hold what can't be fixed[00:32:45] Polyamory as a doorway into deeper relational conversations[00:34:04] Creating a relationship container that doesn't leak energy[00:40:32] Exploring depth together — even where there might be dragons[00:48:17] A shared nervous system and the power of co-regulation[00:49:29] Boundaries, communication, and relational clarity[00:55:46] Relational pillars: emotional, physical, spiritual, sexual[01:10:04] Closing reflections and gratitudeNoteable Quotes “From secure attachment, for what feels like the first time in my life.” – Carrie Cox [04:42]“I love to wade through the muck because I know that's where the alchemy occurs.” – Carrie Cox [12:46]“Setting a container around our relationship that's bigger than both of us, and not leaking any energy outside of it.” – Stephen Karafiath [34:04]“We can go right back down to the depths — you're not afraid to explore coves that might have dragons.” – Stephen Karafiath [40:32]“We've created this shared nervous system, and the benefit is co-regulation.” – Carrie Cox [48:17] Relevant links:Stephen InstagramCarrie's InstagramSubscribe to the podcast: Apple PodcastProduced by NC Productions

“Climate change is the biggest health threat of our century, so we need to train clinicians for a future where it will alter disease patterns, the demand on health systems, and how care is delivered,” says Dr. Sandro Demaio, director of the WHO Asia-Pacific Centre for Environment and Health, underscoring the stakes behind the organization's first regionally-focused climate and health strategy. The five-year plan Dr. Demaio is leading aims to help governments in 38 countries with 2.2 billion people manage rising heat, extreme weather, sea-level change, air pollution and food insecurity by adapting health systems, protecting vulnerable populations, and reducing emissions from the healthcare sector itself. In this timely interview with Raise the Line host Michael Carrese, Dr. Demaio draws on his experiences in emergency medicine, global public health, pandemic response and climate policy to argue for an interconnected approach to strengthening systems and preparing a healthcare workforce to meet the heath impacts of growing environmental challenges. This is a great opportunity to learn how climate change is reshaping medicine, public health and the future of care delivery.  Mentioned in this episode: WHO Asia-Pacific Centre for Environment and Health If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

What if psychedelics could transform the way we treat trauma, chronic pain, and insomnia? This week, neuroscientist and psychedelic researcher Grace Blest-Hopley joins the show to break down the research on psychedelics and female biology. She discusses how psychedelics work in the brain, and the ways that psychedelic-assisted therapies might be beneficial for women in midlife. Links to resources mentioned in this episode: Hystelica’s resources on psychedelic retreats The Heroic Hearts Project Psychedelics and Neuroplasticity: A Systematic Review Unraveling the Biological Underpinnings of Psychedelics Exploring the Therapeutic Effects of Psychedelics Administered to Military Veterans in Naturalistic Retreat Settings The acute effects of classic psychedelics on memory in humans Psilocybin with psychological support for treatment-resistant depression: six-month follow-up Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial Johns Hopkins study on psychedelics and Alzheimer’s Note: In this show, we use “women” as shorthand for people with XX chromosomes. We understand sex and gender are more complex, and acknowledge the experiences we describe reach beyond that word.See omnystudio.com/listener for privacy information.

Hunter Keegan speaks with James Kalupson, AMFT. James is an associate therapist -- as well as a psychedelic facilitator -- who Hunter studied with at Penn State in 2012. Hunter and James discuss mental health treatment and psychedelic therapy. James also appeared on Instalment #50 of Bipolar Recorder. James Kalupson's official website: www.jameskalupson.com Bipolar Recorder is on Twitter / Instagram @BipolarRecorder Hunter Keegan is on Twitter @HHKeegan Thanks for listening! Support Bipolar Recorder at www.bipolarrecorder.com

In this inaugural roundtable discussion, I dive headfirst into one of the most contentious topics at the intersection of faith and science: psychedelics and Christianity. As a relatively new Christian myself, I've been wrestling with what believers should think about these powerful substances—especially after interviewing guests whose lives were transformed by psychedelic experiences, including detransitioners who credit these substances with helping them see through lies they'd built their lives upon.I've gathered four fascinating voices for this conversation, each bringing unique expertise and perspectives. Louie Locke, a pastor of 26 years from Reno, Nevada, rates himself a one out of ten—firmly opposed to psychedelic use from a Christian perspective. He explains his concerns about entering the "second heaven" or spirit realm through means other than Jesus, warning of spiritual doors that may be opened through such substances.Cameron English, a science journalist and director of biosciences at the American Council on Science and Health, brings skepticism from both scientific and theological angles, noting the poor quality of research and drawing parallels to problematic harm reduction movements.Daniel Elliot, an Air Force veteran and counselor who has conducted research on psilocybin and spiritual wellbeing, offers a cautious middle ground as a five, distinguishing between natural substances like psilocybin and synthetic ones like MDMA.Dr. Liza Lockwood, an emergency medicine physician and medical toxicologist, presents the highest rating at seven, explaining her interest in the therapeutic potential for treating refractory depression while sharing the fascinating history of ergot poisoning from the Salem Witch Trials to the discovery of LSD.Together we explore the Greek concept of pharmakeia, whether psychedelics might be connected to the tree of knowledge of good and evil, what harm reduction really means in practice, and whether Christians should be involved in psychedelic-assisted therapy settings. This is just the first in a series exploring these questions—questions that don't have easy answers but deserve thoughtful Christian engagement.Books mentioned:-Imagine Heaven and Imagine The God of Heaven by John Burke-The Great Divorce by C.S. Lewis---WHERE TO FIND THE GUESTSLouie D Locke is the Lead Pastor of Hillside Church in Reno, Nevada, where he has served for 26 years, and also oversees eight churches across Northern Nevada and Eastern California as an Area Pastor. Married to Joni for 36 years with three adult children and eight grandchildren, Louie's life mission is to help people understand and follow God's plan, guiding them toward spiritual wholeness and mature discipleship grounded in biblical integrity. A lifelong learner with passion for history, theology, and thoughtful discussion, he enjoys exploring complex biblical topics and applying Christian principles to everyday life.- X/Twitter: @scoeyd- Church website: hillside4.orgCameron English is a writer, editor and co-host of the Science Facts and Fallacies Podcast. Before joining ACSH, he was managing editor at the Genetic Literacy Project, a nonprofit committed to aiding the public, media, and policymakers by promoting science literacy.- X/Twitter: @CamJEnglish- Website: acsh.org (American Council on Science and Health)- Podcast: Science Facts and Fallacies (with Dr. Liza Lockwood)Daniel Mark Elliott Jr., LMHCA, is a Protestant psychoanalytic counselor specializing in psychosis, dissociation, and cultural fragmentation. An Air Force veteran, psychedelic researcher, and founded Mad River Counseling. He is currently writing a book titled My Psychosis while developing a framework on how minds form reality, coherence, and meaning in fragmented societies.- X/Twitter: @Olaf_The_Third- Website: mad-river.orgDr. S. Eliza Lockwood is an emergency medicine physician and medical toxicologist who completed her fellowship at NYU in 2006 and went on to establish an ACGME-accredited program at Washington University in St. Louis. Driven by a passion for sustainable global health solutions, she has organized humanitarian relief efforts, founded a global health scholar track, and now serves as Medical Affairs Lead for Bayer, focusing on innovative approaches to malnutrition and disease prevention in developing countries. She lectures nationally and internationally on medical toxicology, tropical medicine, and global health.- X/Twitter: @DrLizaMD- LinkedIn: Liza Lockwood- Podcast: Science Facts and Fallacies (with Cameron English)- Weekly X Space: Thursdays 4-6 PM Central (with Cam and John Entine) discussing science and faith topics[00:00:00] Start[00:00:47] Introduction to Psychedelics and Christianity Roundtable[00:02:30] Rating Scale Explained: One to Ten[00:03:25] Louie Locke Introduction: Pastor, Rating One[00:05:23] Cameron English Introduction: Science Journalist, Rating Two[00:07:13] Daniel Elliot Introduction: Veteran and Counselor, Rating Five[00:08:14] Dr. Liza Lockwood Introduction: Toxicologist, Rating Seven[00:09:16] Why This Topic Matters to Stephanie[00:11:30] Louie Explains His Opposition to Psychedelics[00:19:22] Defining Pharmakeia and Biblical Sorcery[00:25:26] Cam's Journey Through Depression to Faith[00:38:17] Daniel on Natural vs Synthetic Substances[00:55:50] Dr. Liza's Scientific Perspective as a Seven[00:57:22] Salem Witch Trials to LSD: A History[01:10:32] Mid-Episode Break[01:19:45] Defining Harm Reduction and Its Failures[01:35:01] Psychedelics and the Tree of Knowledge[01:47:30] Brian Johnson's Psilocybin and Transhumanism[02:01:06] Seeking God in Mistaken Ways[02:05:20] Final Thoughts from the Panel[02:12:45] Where to Find the GuestsROGD REPAIR Course + Community gives concerned parents instant access to over 120 lessons providing the psychological insights and communication tools you need to get through to your kid. Now featuring 24/7 personalized AI support implementing the tools with RepairBot! Use code SOMETHERAPIST2025 to take 50% off your first month.PODCOURSES: use code SOMETHERAPIST at LisaMustard.com/PodCoursesTALK TO ME: book a meeting.PRODUCTION: Looking for your own podcast producer? Visit PodsByNick.com and mention my podcast for 20% off your initial services.SUPPORT THE SHOW: subscribe, like, comment, & share or donate.Watch NO WAY BACK: The Reality of Gender-Affirming Care. Use code SOMETHERAPIST to take 20% off your order.MUSIC: Thanks to Joey Pe...

In Part 2 of Healing or Just High?, Dr. Dawn continues the conversation with Tara Portelli on psilocybin therapy and trauma recovery. Building on Part 1, this episode goes deeper into the real work—integration, accessibility, and what healing actually requires beyond the experience itself.This is an honest, respectful dialogue between two different perspectives, grounded in truth, clinical experience, and the shared goal of helping people heal withoutCheck out Tara's webiste here. Follow her on IG @iamtaraportelli shortcuts.Support the showSupport the showBuyMeaCoffeeFollow Dr. Dawn on IG: @drdawnonthereal and join our broadcast channelWebsites: www.onepps.com www.halainc.org

Let us know what you think! Text us!In this episode of The Security Halt! Podcast, Deny Caballero speaks with Ben Kramer, a Marine Corps veteran, firefighter, and licensed psilocybin facilitator, about the transformative role of psychedelic medicine in veteran mental health.They discuss:Trauma, worthiness, and identity after servicePsilocybin as a tool for healing—not a shortcutThe importance of preparation and integrationNeuroplasticity, awe, and mindfulnessCommunity, gratitude, and post-military purposeBreaking stigma around psychedelicsAddressing the veteran suicide crisisThis is a grounded, honest conversation about healing beyond the battlefield.Chapters:00:00 – Psilocybin and Veteran Healing Explained 02:58 – Ben Kramer's Military to Healing Journey 06:05 – Why Peer Support Matters for Veterans 08:59 – Preparation and Integration in Psilocybin Therapy 11:56 – Trauma, Worthiness, and Identity 14:55 – Awe, Neuroplasticity, and Mental Health 17:59 – Mindfulness and Breathwork for Healing 20:46 – Compassion in Veteran Mental Health Care 24:03 – Exploring Alternative Healing Modalities 26:50 – Creating Safe Spaces for Psychedelic Healing 29:18 – Hypervigilance and the Cost of Constant Readiness 30:49 – Addressing Veteran Suicide 32:53 – Breaking the Psychedelic Stigma 34:29 – Psychedelics as a Catalyst for Change 37:21 – Ego, Insight, and Integration 40:04 – Why Chasing Treatments Doesn't Work 42:52 – Doing the Work After the Experience 46:10 – Community as the Foundation of Healing 50:39 – Transitioning from Military to Civilian LifeSponsored by: Dr. Mark Gordon & Millennium Health Centers  Get the book Peptides for Health Vol.1 Medical Edition today.  Use code PTH25 for 25% off through March 15  Use code Phase2P for 10% off Millennium products  Available only at MillenniumHealthStore.comPRECISION WELLNESS GROUP  Use code: Security Halt Podcast 25Website: https://www.precisionwellnessgroup.com/ Security Halt Mediahttps://www.securityhaltmedia.com/Connect with Ben Today!LinkedIn: https://www.linkedin.com/in/ben-kramer-16846127a/Website: www.fungimentalpdx.com  Instagram: @securityhaltX: @SecurityHaltTik Tok: @security.halt.podLinkedIn: Deny CaballeroSupport the showProduced by Security Halt Media

One on One Video Call W/George https://tidycal.com/georgepmonty/60-minute-meetingSupport the show:https://www.paypal.me/Truelifepodcast?locale.x=en_US“Follow me, and I'll make you governor of an island.”In Don Quixote, a poor farmer named Sancho Panza leaves his wife, his kids, and everything he knows to follow a lunatic into the wilderness. Why? Because he was promised an island.Sound familiar?“Work hard and you'll make partner.”“Grind now, equity later.”“We're a family here - your loyalty will be rewarded.”“Be your own boss - unlimited earning potential.”We're all Sancho Panza now. Following someone else's quest, enduring the chaos, waiting for an island that might never come - or worse, comes in a form we never actually wanted.This episode explores what happens when the everyman follows the madman's promise. What Cervantes understood about gig economy exploitation 400 years before Uber existed. And why Sancho's choice at the end might be the most radical thing you hear all year.Part 2 of “The Wisdom of Don Quixote” series. One on One Video call W/George https://tidycal.com/georgepmonty/60-minute-meetingSupport the show:https://www.paypal.me/Truelifepodcast?locale.x=en_US

One on One Video Call W/George https://tidycal.com/georgepmonty/60-minute-meetingSupport the show:https://www.paypal.me/Truelifepodcast?locale.x=en_USIs Your Vision Real or Are You Delusional?Don Quixote descended into a cave.He was down there for one hour.When they pulled him back up, he was pale, shaking, transformed. And he told them an impossible story:“I was in an enchanted palace. For three days. I met legendary knights. I saw magical maidens. I witnessed wonders I can barely describe.”Sancho looked at him. “Master, you were down there for an hour. Maybe less.”Don Quixote's voice wavered. For the first time in the entire novel, he seemed… uncertain.“I know what I saw,” he said. Then, quieter: “God knows the truth.”This is the Cave of Montesinos. The most mysterious, psychologically complex scene in all of Don Quixote.And it asks the question every visionary, creator, entrepreneur, and dreamer faces:How do you know if what you saw in the dark was real… or if you just made it all up?I've had 860 conversations on this podcast. And I keep coming back with the same vision: I see genius in people that the world doesn't validate. I see systems rigged against passion. I see the fight itself as what keeps us alive.But what if I'm just Don Quixote in the cave? What if I descended into the darkness with my own expectations and came back up with a beautiful story that isn't real?What if your calling is just a dream you had in the dark?What if the business idea that won't leave you alone is delusion dressed as vision?What if the injustice you see so clearly is just confirmation bias?You'll never know for sure.And that's the point.This episode is about what Don Quixote learned in that cave: Certainty is madness. Doubt is wisdom. And acting on your vision despite the doubt—that's the only courage that matters.“Time will tell,” Don Quixote said when asked if his vision was real.That's all any of us can say. One on One Video call W/George https://tidycal.com/georgepmonty/60-minute-meetingSupport the show:https://www.paypal.me/Truelifepodcast?locale.x=en_US

In this encore episode of the Psychedelic Medicine Podcast, psychedelic science researcher and educator Dr. Manesh Girn discusses his studies investigating psychedelic brain action. Manesh earned PhD in neuroscience at McGill University and is an author on over a dozen peer-reviewed articles on psychedelics and related topics. He is also chief research officer at EntheoTech Bioscience and runs the YouTube channel the Psychedelic Scientist.  In this conversation, Manesh discusses his recent article in Trends in Cognitive Sciences titled "A complex systems perspective on psychedelic brain action."He explains the complexity science approach used in the article, which emphasizes the brain is a holistic, interconnected system, rather than individual component networks that can be isolated. From this standpoint, Manesh critiques some simplistic explanations of the neural mechanisms of psychedelics which focus exclusively on interactions with the default mode network isolated from other brain systems. He also explains how individual some of the neural effects of psychedelics are, citing different findings from different studies and observed variations between brain scans of different people. By better understanding these individual differences, and placing these different responses into a complexity science framework, Manesh believes that more individually-tailored psychedelic therapies are possible once the systems involved are more comprehensively understood.  Manesh closes this discussion by explaining the difference between genuine complexity and sheer chaos.  Complexity, he explains, is a delicate balance of novelty and order, which is why psychedelic experiences can be both destabilizing and productive of novel insights and personal transformation.    In this episode: The research into psychedelics and the default mode network Using frameworks from complexity science in psychedelic research Measuring entropy in the brain Differences in neurological effects from taking between different studies and different individuals How a complexity science approach to neuroscience could better inform precision psychiatry   Quotes: "You can't just look at a specific brain region or network [in psychedelic research], you've gotta talk about the brain as a whole, in this sense of seeing the brain as a system of interacting parts." [4:49] "The core idea of this paper is that psychedelics put our brain into this state that is more dynamically flexible, it's more diverse in its activity patterns, and it's more sensitive to inputs that come in." [14:17] "What we find in the brain imaging findings is that different studies disagree, but also if you look at individual people, they can have radically different effects on their brain—almost opposite." [21:37]   Links: Manesh' recent article in Trends in Cognitive Sciences: "A complex systems perspective on psychedelic brain action" ​​Psilocybin vs Placebo Brain Connectivity Diagram from Dr. Robin Carhart-Harris The Psychedelic Scientist YouTube Channel The Psychedelic Scientist on Instagram The Psychedelic Scientist on Twitter Manesh on LinkedIn EntheoTech website Psychedelic Medicine Association Porangui

Oregon became the first in the nation to legalize psychedelic therapy through psilocybin back in 2020. What soon followed were bans in various jurisdictions, large costs for individuals seeking treatment and other barriers to access. Now, new reporting from The New York Times found that a third of psilocybin service centers have closed and other states have also begun offering this therapy, including Colorado and New Mexico. Andrew Jacobs is a health and science reporter for the NYT. He joins us to share more on where things stand in Oregon’s program and what other states have learned from the state’s first-in-the-nation rollout. 

Revisiting this episode of The Observatory, in a time when it is much needed in our country, Scott and LaRae discuss the profound concept of healing, exploring what it truly means, emphasizing why we crucially need healing, and guiding us through the transformative journey to achieve inner healing. Hear why the healing journey is so personal, how your belief system impacts it, and the things in your life that can ignite it. They also share the steps to take in your healing journey and why it's important to let go of the need always to be right. Timestamps[03:44] What is a healing journey?[10:58] Why the healing journey is so personal[13:04] God is a mirror[18:03] How your belief system impacts your healing journey [21:02] The book: Wonderland by Steven Johnson[27:33] The evolution of taste, music, and fashion [34:00] How the mind works [43:03] The moments in your life that can ignite your healing journey [50:34] The steps to take in your healing journey[53:34] The importance of letting go of the need to be right Notable quotes:“A healing journey starts from the desire to become more aware of yourself.” - LaRae Wright [05:12]“Everyone is a mirror, and we get to see different perspectives of other people's lives.” - Scott [13:08]“Your belief system is going to limit your ability to see other things differently.” - Scott [18:05]“Just because we think differently doesn't mean we can't be friends.” - LaRae Wright [29:37]Relevant links:LaRae Instagram: @larae_wrightScott Instagram: @scott_david_wrightThe book: Wonderland by Steven JohnsonSubscribe to the podcast: Apple PodcastProduced by NC Productions

We have a special episode of Raise the Line on tap today featuring the debut of host Dr. Parsa Mohri, who will now be leading our NextGen Journeys series that highlights the fresh perspectives of learners and early career healthcare professionals around the world on education, medicine, and the future of care. Parsa was himself a NextGen guest in 2024 as a medical student at Acibadem University in Turkey. He's now a general physician working in the Adult Palliative Care Department at Şişli Etfal Research and Training Hospital in Istanbul.  Luckily for us, he's also continuing in his role as a Regional Lead for the Osmosis Health Leadership Initiative (OHLI). For his first guest, Parsa reached out to a former colleague in the Osmosis family, Negeen Farsio, who worked with him as a member of OHLI's predecessor organization, the Osmosis Medical Education Fellowship. Negeen is now a graduate student in medical anthropology at Brunel University of London, a degree which she hopes will inform her future work as a clinician. “Medical anthropology is a field that looks at healthcare systems and how human culture shapes the way we view different illnesses, diseases, and treatments and helps you to see the full picture of each patient.” You are sure to enjoy this heartfelt conversation on how Negeen's lived experience as a patient and caregiver have shaped her commitment to mental health and patient advocacy, and how she hopes to marry humanity with medicine in a world that yearns to heal. If you like this podcast, please share it on your social channels. You can also subscribe to the series and check out all of our episodes at www.osmosis.org/podcast

Gabe Charalambides is the founder of Odyssey, the world's leading provider of psilocybin-assisted therapy, and a Stanford-trained aerospace engineer whose personal experience with anxiety helped shape a mission: making psychedelic healing safer, more responsible, and more accessible to everyday people. After years working alongside leading psychedelic organizations, Gabe launched Odyssey in 2023 and helped open the first legal psilocybin retreat in the U.S., rooted in screening, preparation, and evidence-based support.In this conversation, we explore what psilocybin therapy can look like when done responsibly—why education, intention-setting, and integration matter as much as the ceremony itself. Gabe explains how psilocybin may reduce mental rigidity, increase psychological flexibility, and help people move through trauma, rumination, and fear—especially the existential distress that can come with a cancer diagnosis. We also break down what a guided experience typically involves (screening, preparation sessions, a full-day facilitated journey, and post-session integration), what outcomes Odyssey is tracking through an IRB-approved study, and why many participants describe their experience as one of the most meaningful of their lives.If you've been curious about psychedelics but unsure what “safe” really means—or you're navigating chronic illness, anxiety, or trauma and looking for new tools—this episode offers a grounded, practical look at what's real, what's promising, and what to consider before taking the next step. To learn more, visit https://www.odysseypbc.com/Key Topics CoveredGabe's background: Stanford-trained aerospace engineer → founder of OdysseyHow anxiety, OCD, and meditation shaped his approach to mental healthWhy psilocybin can help “unstick” rigid thought patterns and emotional loopsWhat a safe, legal psilocybin-assisted therapy process looks like (screening → prep → session → integration)“Set and setting” explained: why environment and support dramatically change outcomesSpiritual and psychological effects people commonly report (connection, meaning, reduced fear of death)Microdosing vs. full-dose therapy: differences, evidence, and expectationsSafety considerations: contraindications, unpleasant experiences, and why support mattersOdyssey's IRB-approved outcomes study and what they're measuring (wellbeing, anxiety, flexibility, mindfulness)How this work may support cancer patients facing existential distress and fear -----------------------------------------------A Better Way to Treat Cancer: A Comprehensive Guide to Understanding, Preventing and Most Effectively Treating Our Biggest Health ThreatGrab my book here: https://www.amazon.com/dp/B0CM1KKD9X?ref_=pe_3052080_397514860 Unleashing 10X Power: A Revolutionary Approach to Conquering CancerGet it here: https://store.thekarlfeldtcenter.com/products/unleashing-10x-powerPrice: $24.99100% Off Discount Code: CANCERPODCAST1 Healing Within: Unraveling the Emotional Roots of CancerGet it here: https://store.thekarlfeldtcenter.com/products/healing-withinPrice: $24.99100% Off Discount Code: CANCERPODCAST2-----------------------------------------------Integrative Cancer Solutions was created to instill hope and empowerment. Other people have been where you are right now and have already done the research for you. Listen to their stories and journeys and apply what they learned to achieve similar outcomes as they have, cancer remission and an even more fullness of life than before the diagnosis. Guests will discuss what therapies, supplements, and practitioners they relied on to beat cancer. Once diagnosed, time is of the essence. This podcast will dramatically reduce your learning curve as you search for your own solution to cancer. To learn more about the cutting-edge integrative cancer therapies Dr. Karlfeldt offer at his center, please visit www.TheKarlfeldtCenter.com

In this episode of The Observatory Podcast, Scott and LaRae Wright sit down with Jennifer Holland for a deeply grounded conversation about what it means to come home to yourself—through the body.Jennifer shares how her life unfolded in “two large chapters,” including growing up LDS, navigating anxiety, and untangling the places where external authority and internal knowing got crossed. Together, they explore somatic wisdom, nervous system trust, relational safety, and what it looks like to create containers where the body can finally exhale.If you've ever felt stuck in your head, unsure who to trust (including yourself), or curious about embodiment as a path to healing—this episode offers a compassionate, practical doorway inward.Timestamps:[00:01:00] Welcoming Jennifer Holland[00:01:20] Scott: coming in “open” and letting the conversation unfold[00:02:00] Jennifer: “two different large chapters” + growing up LDS[00:02:36] Anxiety as a formative thread in childhood/young adulthood[00:04:30] “Mind, Body, Spirit” class + early expansion beyond the script[00:06:39] Divorce + faith questioning + beginning to re-orient inward[00:10:06] Discernment: “Do I trust these people?” (authority vs inner knowing)[00:16:27] When intuition gets twisted (and what it costs)[00:19:32] The body path: yoga, breathwork, sensual touch, massage[00:31:29] Trust + boundaries: holding containers that let people soften[00:36:56] Nervous system relaxation + why safety changes everything[00:37:06] Deep safety without sex “on the table” (deconditioning performance)[00:45:45] Jennifer: slow trust + letting time reveal what's true[00:54:15] “What keeps your breath breathing?” (presence and the unseen support)[00:55:00] Breath as steady baseline (even when life isn't)[00:58:25] Retreat/container rhythm: arriving, stillness, breath, connection[01:09:34] Closing reflections + gratitudeNotable Quotes:“I said, you know, we like to come into these podcasts pretty open and just allowing it to unfold as it unfolds.” — Scott Wright [00:01:20]“I feel like my life has two different large chapters.” — Jennifer Holland [00:02:00]“And I was riddled with anxiety most of my childhood and teenhood and young adulthood.” — Jennifer Holland [00:02:36]“I did take a class called Mind, Body, Spirit, though, that really expanded my mind.” — Jennifer Holland [00:04:30]“I was going through my first divorce, so I was just like, I don't know about the church…” — Jennifer Holland [00:06:39]“Even just like, do I trust these people… and should I be following them?” — Jennifer Holland [00:10:06]“It was starting to kill me essentially, started to twist my intuition up.” — Jennifer Holland [00:16:27]“So what happens when we can attune our nervous systems to deep safety without sex even being on the table.” — Jennifer Holland [00:37:06]“So my, my nervous system takes a really long time to actually trust.” — Jennifer Holland [00:45:45]“What keeps your breath breathing?” — Jennifer Holland [00:54:15]“Your breath has been breathing at the exact same rhythm.” — Jennifer Holland [00:55:00]Relevant Links:www.drippractice.comwww.instagram.com/drippracticewww.instagram.com/strongandsultryor email her directly at Jen@strongandsultry.comSubscribe to the podcast: Apple PodcastProduced by NC Productions

Watch every episode ad-free & uncensored on Patreon: https://patreon.com/dannyjones Stuart Hameroff is an astrobiologist, retired anesthesiologist and leader of the Science of Consciousness conferences at the University of Arizona. Hameroff is best known for his controversial belief that consciousness originates from quantum states in neural microtubules. SPONSORS https://prizepicks.onelink.me/LME0/DANNY - Use code DANNY to get $50 in lineups when you play your first $5 lineup. https://shopmando.com - Use code DANNY to get $5 off your Starter Pack. https://dupe.com - Find similar products for less - 100% free to use. https://whiterabbitenergy.com/?ref=DJP - Use code DJP for 20% off EPISODE LINKS https://x.com/StuartHameroff https://consciousness.arizona.edu/science-consciousness-2026 FOLLOW DANNY JONES https://www.instagram.com/dannyjones https://twitter.com/jonesdanny OUTLINE 00:00 - Connection between anesthesia & consciousness 02:14 - How anesthesia works 08:54 - Overdosing vs. underdosing anesthesia 12:31 - Scariest patients to administer anesthesia to 15:45 - Why computers can't replicate consciousness 21:18 - Consciousness & the collapse of the wave function 29:15 - Consciousness is fundamental, not emergent 30:19 - Simulation theory is a "cop-out" 34:29 - NASA's OSIRIS-REx Asteroid sample return mission 40:56 - The origin of life on Earth 42:20 - Microtubules & time crystals 43:58 - Evidence of consciousness in plants 46:27 - Why microtubules could be the source of consciousness 48:25 - Can AI develop consciousness? 53:48 - Psilocybin consciousness experiment 55:08 - What happens to consciousness when the body dies 01:01:53 - Consciousness is controlled by our subconscious 01:03:32 - How evolution is driven by consciousness & pleasure 01:06:47 - Life is the vehicle for consciousness 01:10:32 - How to create consciousness from scratch 01:13:13 - Consciousness in the afterlife & reincarnation 01:15:23 - Consciousness is a hologram 01:17:35 - How psychedelics elevate consciousness 01:23:25 - The logic of dreams 01:25:37 - memories encoded in organ transplants 01:32:07 - How to confirm microtubules hypotheses 01:35:53 - The leading Alzheimer's treatment is a scam 01:41:41 - Top Alzheimer's treatment researchers VANISHED 01:44:20 - New theoretical Alzheimer's cure 01:50:08 - Beneficial effects of ultrasound therapy 01:53:58 - Dangers of ultrasound technology 01:59:18 - New study on ultrasound on the brain 02:06:11 - Proof of ultrasound reversing Alzheimer's 02:09:10 - Quantum consciousness + parapsychology 02:16:42 - Neuron biology & why the brain is more than a computer 02:20:09 - Suspicious movement of plasma ball lightning 02:23:18 - Anesthesia vs. the corona effects Learn more about your ad choices. Visit podcastchoices.com/adchoices