The Gary Null Show

Boosting a Natural Molecule (NAD+) Reverses Alzheimer's Brain Damage in New Study University of Oslo & Ullevaal University Hospital (Norway), February 8, 2026   One of the key drivers of brain dysfunction in Alzheimer's disease (AD) is the protein tau. Under normal conditions, tau helps maintain the internal structure of neurons, supporting the transport systems that allow nerve cells to function properly. In Alzheimer's disease, however, tau becomes abnormally modified and begins to clump together. These aggregates interfere with normal cellular transport, damage neurons, and ultimately contribute to memory impairment. Now, an international team of scientists has identified a previously unrecognized way to protect the brain from this degeneration. Their research shows that increasing levels of the naturally occurring molecule NAD⁺ can counteract neurological damage linked to Alzheimer's disease.  Previous research has suggested that boosting NAD⁺ using precursor compounds such as nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN) can produce beneficial effects in animal models of AD and in early-stage clinical studies. However, the biological processes responsible for these effects have remained poorly understood,” explains first author Alice Ruixue Ai. The new study reveals that NAD⁺ works through a previously unidentified RNA-splicing pathway. This pathway is regulated by a protein called EVA1C, which plays an essential role in the process of RNA splicing. RNA splicing allows a single gene to produce multiple isoforms of a protein, and one isoform may show distinctive effects on the other isoforms. Its dysregulation is one of the most recently acknowledged risk factors for AD.        

HEALTH NEWS   Choline intake in pregnancy linked to lower inflammation Fatty acids found to influence immune defense during chronic infections Online shopping and social media use linked to higher stress levels Scientists Discover Natural Compounds With Unexpected Benefits for Skin, Anti-Aging, and Heart Health Discrimination damages the body—and makes victims age faster   Choline intake in pregnancy linked to lower inflammation Cornell University, February 5 2026 (Eurekalert)   A new Cornell University study suggests that choline, a nutrient many pregnant people consume too little of, may play an underappreciated role in keeping inflammation in check during pregnancy. Choline is an essential nutrient involved in many biological processes, including cell membrane structure, neurotransmitter production, methylation, immune cell receptor agonism, and fetal brain development, and some of these biochemical processes play a role in the regulation of inflammation. It is found primarily in eggs, meat, fish, dairy and some legumes and cruciferous vegetables. Researchers analyzed data from more than 1,300 pregnant participants enrolled in the Alberta Pregnancy Outcomes and Nutrition (APrON) cohort, one of the most detailed long-running pregnancy nutrition studies in North America. They found that higher recent dietary choline intake was associated with lower levels of inflammation in the third trimester. Most strikingly, participants with the highest choline intakes had dramatically lower odds of having clinically elevated inflammation than those with the lowest intakes.The current recommendation for choline during pregnancy is 450 mg, but there's some evidence that that may not be enough.     Fatty acids found to influence immune defense during chronic infections University of California at San Diego, February 5 2026 (Medical Xpress) Our immune system implements an array of strategies to combat threatening infections. White blood cells called cytotoxic T lymphocytes or "CD8 T cells" are soldiers of the immune system, serving as defensive agents that fight invading pathogens. When CD8 T cells reach the point of exhaustion, their protective capabilities decline and the immune system is much less effective. University of California San Diego immunologists have now studied the influences related to metabolism and the environment surrounding CD8 T cells. Their study led to intriguing new insights on the role of fatty acids in chronic infections and other persistent conditions, such as tumors. The research focused on metabolites, including small molecules such as amino acids, sugars, and lipids, in mice that play key roles in metabolism and its many functions and pathways. The study examined how such metabolites circulating in the blood change during short-lived or long-lasting viral infections. They discovered that an ongoing viral infection causes a brief but striking shift in the availability of nutrients in the early stages after infection. They saw levels of fatty acids increase during the first week after infection, associated with infection-induced changes in eating behavior and fat breakdown. At the same time, a special group of exhausted CD8 T cells with stem-like properties was found to absorb and store more fat than other T cells. These cells were able to use fatty acids as an energy source to power their mitochondria, the cell's energy producers. When fatty acids were provided later during chronic infection, the number of stem-like T cells expanded.   Online shopping and social media use linked to higher stress levels     Aalto University (Finland), January 9 2026 (News-Medical) Planning to save time by doing your shopping online? If so, it's possible you're not doing your well-being any favors. A study from Aalto University in Finland has found that online shopping is more strongly linked to stress than reading the news, checking your inbox or watching adult entertainment.  Previous studies have shown that social media and online shopping are often used to relieve stress. However, the new results show that a rise in social media use or online shopping is linked to an increase in self-reported stress across multiple user groups and across devices. The study found that users of YouTube and streaming services, as well as online gamers, also reported increased stress levels. For people experiencing high-stress, time spent on social media was twice more likely to be linked to stress as compared to time spent on gaming. Somewhat surprisingly, people who spent a lot of time on news sites reported less stress than others. On the other hand, those who already experienced a lot of stress didn't spend much time on news sites. Overall, the study found a strong connection between internet use, in general, and heightened stress, especially among those who already experienced a lot of stress in daily life. Women reported more stress than men, and the older and wealthier the participant, the less stress they experienced.   Scientists Discover Natural Compounds With Unexpected Benefits for Skin, Anti-Aging, and Heart Health Meijo University (Japan), February 5, 2026 (SciTech Daily) Scientists have found that certain natural compounds produced by algae and cyanobacteria may offer benefits beyond sun protection, including support for skin health and cardiovascular function. In lab experiments, two mycosporine-like amino acids were found to do more than soak up ultraviolet light. They also slowed down a major enzyme tied to blood pressure control, while showing antioxidant and anti-aging activity. One enzyme, Porphyra-334, is abundant in edible seaweed, which is already consumed widely in many countries. This raises the possibility that everyday foods may contain underappreciated bioactive compounds worthy of further health-related research.These compounds, called mycosporine-like amino acids (MAAs), are produced by seaweeds and other tiny organisms that spend their lives exposed to intense light. MAAs work like built in sun filters by absorbing ultraviolet (UV) radiation before it can harm cells. One of the most notable findings came from experiments on the inhibiting the angiotensin-converting enzyme ACE, a key regulator of blood pressure. Many widely prescribed hypertension drugs work by blocking ACE. Both compounds reduced the activity of this enzyme in laboratory tests, marking the first report of such an effect for MAAs. Although the observed effects were moderate and measured outside the human body, the discovery opens a new direction for future research.     Discrimination damages the body—and makes victims age faster University of Montreal, January 19 2026 (Medical Xpress) Has being discriminated against as an LGBTQ+ person been so bad, the stress so heavy, that the victim can literally feel it in their bones? Well, it turns out that's exactly what happens: discrimination damages the body and brain. That's the conclusion of a new study by researchers at Université de Montréal, who found that discrimination against sexually and gender-diverse people leaves measurable biological traces in the body—so much so, it should be considered a chronic health burden. Published in Psychoneuroendocrinology, the study was done on 357 Montreal adults aged 18 to 79: They included 129 cisgender sexual minority men and women, 96 transgender and non-binary people, and 72 cisgender heterosexual men and women. UdeM researchers measured the participants' allostatic load, the cumulative biological wear-and-tear associated with chronic stress. They looked at 16 biomarkers affecting the subjects' cardiovascular, metabolic, neuroendocrine and immune systems. Results show that major life experiences of discrimination and daily microaggressions were positively associated with allostatic load. This means that these two types of discriminatory events independently contribute to physiological dysregulation, creating a cumulative health burden and accelerated aging. The study revealed significant disparities: people on the male spectrum (cisgender and transgender men) had the highest levels of allostatic load, while sexual minority men (bisexual and gay) also showed high levels of biological stress.

The third part of Gary's commentary on the Healthcare System in America

How To Fix Our Broken Medical System: 

How To Fix Our Broken Medical System: 

The Illusion of Modern Medicine Why Our Most Advanced Healthcare System Still Fails at Healing “We spend more money treating disease than any society in history yet remain among the sickest—because healing was never the system's goal.” Gary Null PhD

Ancient Chinese Herb Shows Promise as a Powerful New Treatment for Common Hair Loss Continued exposure to certain heavy metals linked to ADHD in childhood Scientists Discover a Simple, Drug-Free Way To Reduce Anxiety in 24 Minutes Depression and anxiety together raise long COVID risk in older women Cannabis shows anti-migraine benefits

HEALTH NEWS   Wild Blueberries May Benefit the Heart, Metabolism, and Microbiome Nitrate in drinking water linked to increased dementia risk while nitrate from vegetables is linked to a lower risk, researchers find   Afternoon naps clear up the brain and improve learning ability Screen time may increase body fat in children Simple dietary change may slow liver cancer in at-risk patients Wild Blueberries May Benefit the Heart, Metabolism, and Microbiome University of Maine & Florida State University, January 28, 2026 (SciTech Daily) A newly published scientific review brings together a growing body of research on how wild blueberries may influence cardiometabolic health. This area of health includes measures such as blood vessel function, blood pressure, blood lipids (cholesterol and triglycerides), and blood sugar (glucose). The review was developed following an expert symposium. Twelve specialists took part, representing fields that included nutrition, food science, dietetics, nutrition metabolism and physiology, cardiovascular and cognitive health, gut health and microbiology, and preclinical and clinical research models.  The paper evaluates findings from 12 human clinical trials conducted over 24 years across four countries that examined the cardiometabolic effects of wild blueberries. Across the clinical research examined, improvements in blood vessel function stand out as one of the most reliable findings. Studies included in the review suggest that wild blueberries may support endothelial function (or how well blood vessels relax and respond to stimuli). Some trials reported effects within hours of a single serving, while others observed benefits after consistent intake over weeks or months. In one six-week clinical study highlighted in the review, adults who consumed 25 grams of freeze-dried wild blueberry powder each day showed increases in beneficial Bifidobacterium species. The authors identify the gut microbiome as a likely contributor to the cardiometabolic effects linked to wild blueberries. The review also suggests wild blueberry intake may support certain aspects of cognitive performance. Improvements were observed in measures such as thinking speed and memory. Several of the reviewed studies reported clinically meaningful improvements in blood pressure, blood sugar regulation, and lipid markers, including total cholesterol, LDL cholesterol, and triglycerides, after weeks of wild blueberry consumption.   Nitrate in drinking water linked to increased dementia risk while nitrate from vegetables is linked to a lower risk, researchers find   Edith Cowan University (Australia) &  Danish Cancer Research Institute, January 28 2026 (Eurekalert) New research from Edith Cowan University (ECU) and the Danish Cancer Research Institute (DCRI) investigated the association between the intake of nitrate and nitrite from a wide range of different sources, and the associated risk of dementia.  The research, which investigated the association between source-specific nitrate and nitrite intake and incident and early-onset dementia, followed more than 54,000 Danish adults for up to 27 years and found that the source of nitrate was of critical importance in a diet.  The researchers found that people who ate more nitrate from vegetables had a lower risk of developing dementia, while those who consumed more nitrate and nitrite from animal foods, processed meats, and drinking water, had a higher risk of dementia.  When we eat nitrate-rich vegetables, we are also eating vitamins and antioxidants which are thought to help nitrate form the beneficial compound, nitric oxide, while blocking it from forming N-nitrosamines which are carcinogenic and potentially damaging to the brain.  Unlike vegetables, animal-based foods don't contain these antioxidants. In addition, meat also contains compounds such as heme iron which may actually increase the formation of N-nitrosamines. This is why nitrate from different sources may have opposite effects on brain health.   This is the first time that nitrate from drinking water has been linked to higher risks of dementia. The study found that participants exposed to drinking-water nitrate at levels below the current regulatory limits, had a higher rate of dementia.   Water doesn't contain antioxidants that can block formation of N-nitrosamines. Without these protective compounds, nitrate in drinking water may form N-nitrosamines in the body.   Afternoon naps clear up the brain and improve learning ability University of Freiburg (Germany) & University of Geneva, January 28 2026 (Eurekalert) Even a short afternoon nap can help the brain recover and improve its ability to learn. In a study published  in the journal NeuroImage, researchers at the  University of Freiburg and the University of Geneva show that even a nap is enough to reorganize connections between nerve cells so that new information can be stored more effectively.  The new study shows that a short sleep period can relieve the brain and put it back into a state of readiness to learn – a process that could be particularly beneficial for situations with high work load. The study examined 20 healthy young adults who either took a nap or stayed awake on two afternoons. The afternoon nap lasted on average 45 minutes.  The results showed that after the nap, the overall strength of synaptic connections in the brain was reduced – a sign of the restorative effect of sleep. At the same time, the brain's ability to form new connections was significantly improved. The brain was therefore better prepared for learning new content than after an equally long period of wakefulness. Screen time may increase body fat in children Ningbo University (China), January 15 2026 (News-Medical) A study published in Frontiers in Endocrinology reveals that higher screen time is associated with higher levels of body fat accumulation and less favorable obesity-related metabolic indicators in school-aged children, and that cardiorespiratory fitness can significantly influence this association. The study included a total of 1,286 third-grade students from six schools in Ningbo. Participants' cardiorespiratory fitness was assessed using the 20-meter shuttle run test. Information on screen time, physical activity, and diet quality was obtained from self-reported questionnaires. The study analysis indicated that higher screen time is significantly associated with increased visceral fat accumulation, body fat mass index, and body fat percentage, and with lower cardiorespiratory fitness and slightly lower blood levels of HDL-C. The study found that participants with more than two hours of daily screen time exhibit significantly increased visceral fat, fat mass index, and fat percentage, and significantly reduced cardiorespiratory fitness compared to those with less than two hours of daily screen time. Simple dietary change may slow liver cancer in at-risk patients Rutgers University, January 29 2026 (Medical Xpress) People with compromised liver function may be able to reduce their risk of liver cancer or slow its progression with a simple dietary change: eating less protein. A Rutgers-led study has found that low-protein diets slowed liver tumor growth and cancer death in mice, uncovering a mechanism by which a liver's impaired waste-handling machinery can inadvertently fuel cancer. When people consume protein, the nitrogen can be converted into ammonia, a substance that's toxic to the body and brain. A healthy liver typically processes this ammonia into harmless urea, which is excreted via urine. The clinical observation that the liver's ammonia-handling machinery is usually impaired in liver cancer patients is decades old. Zong's team utilized a technique to induce liver tumors in mice without crippling the ammonia-disposal system. The researchers then used gene-editing tools to disable ammonia-processing enzymes in some—but not all. The results were striking: Mice with disabled enzymes and higher ammonia levels developed heavier tumor burdens and experienced a much faster rate of mortality than those with functioning systems. The researchers then tested a straightforward intervention: reducing dietary protein. Mice fed low-protein food exhibited dramatically slower tumor growth and lived significantly longer than those that received food with standard levels of protein BREAK   Introducing the Clips For Today  Sharmine Narwani : The Slow Strangling of Syria and Lebanon - 4:55  Inventing a pandemic - by Maryanne Demasi, PhD - MD REPORTS - full - 2:49    Did Covid mRNA boosters train the immune system to stand down? - full (Maryanne Demasi)  -2:38   Bryce Nickels on X: "-@R_H_Ebright explains why dangerous gain-of-function research should be BANNED https://t.co/2TaLBzzkU0" / X - full (Richard E Bright explains why dangerous gain of function research should be banned)  - 3:17 

For most Americans, and certainly for baby boomers, we remember the first major exposé before Congress during the Church Committee hearings, when William Colby, the head of the CIA admitted under oath that the agency had its tentacles in much of the American mainstream media and promulgated bogus stories for citizens to consume.  On the second half of the program Gary pays tribute to Dr. Peter Duesberg who is a subject in the Gary Null documentary 'Aids the Untold Story'  

The Study Cardiology Willfully Ignored for Over Two Decades Written by Sayer Ji on January 27, 2026. Posted in Current News' https://principia-scientific.com/the-study-cardiology-willfully-ignored-for-over-two-decades/     Authored by Lois Lamerato et al. from Henry Ford Health System study by Lois Lamerato et al  of data from Michigan's integrated healthcare system in Michigan to compare chronic health outcomes in vaccinated versus unvaccinated children. Vaccination exposure was defined as receiving at least one vaccine Vaccinated children had a 2.5 higher adjusted hazard ratio for any chronic condition Specific increcases include asthma, autoimmune disease, atopic disease, eczema, and neurodevelopmental disorders. The 10-year probability of being free from chronic conditions was 83% in unvaccinated vs. 43% in vaccinated. No conditions were higher in unvaccinated.   Study by AR Mawson et al – J Translational Science Survey-based study compared homeschooling children who were vaccinated versus unvaccinated. Higher rates of neurodevelopmental disorders, asthma, and allergies among vaccinated children Vaccinated children had fewer vaccine-preventable infections.   Study by BS Hooker et al – SAGE Open Medicine Retrospective analysis of health outcomes between vaccinated and unvaccinated children. Higher rates of asthma, developmental delays and ear infections in vaccinated children.   Study by NZ Miller – J Translational Science A follow-up analysis to adjust for additional covariates such as breastfeeding and cesarean birth. Reported increased odds of certain chronic conditions among vaccinated children. This is not very convincing study if I am to be honest   Study by AR Mawson & BS Hooker – Frontiers of Public Health Analyzed pediatric billing data and reported increased office visits and diagnoses among vaccinated children. Reported igher rates of neurodevelopmental disorders, asthma, and allergies in vaccinated children However, the journal retracted this article on the grounds it did not disclose conflicts of interest   University of Hong Kong -- This one I know from memory – don't know the journal Double blind placebo study comparing flu vaccinated vesus saline placebo vaccinated Followed for 9 months Vaccinated – almost 4-fold increase in getting other non-flu respiratory infections compared to unvaccinated Only slight increase in flu cases among unvaccinated compared to vaccinated   DeStefano et al -- J Translational Neurdegeneration Study analyzed children in metropolitan Atlanta to examine a link between the age of first MMR vaccine receipt and autism diagnosis. Reports that earlier MMR vaccination increased autism risk in specific subgroups, compared to to later-vaccinated children.   J Lyons-Weiler – Intl J Environmental Research and Public Health Unvaccinated children reportedly had fewer chronic illnesses but more vaccine-preventable infections.   Roma Schmitz et al -  Deutsch Arztebl Intl (German journal) – early study in 2011 Large survey to assess whether vaccination status affects infectious and atopic diseases. Unvaccinated had higher vaccine-preventable diseases (e.g., pertussis, measles) but lower atopic diseases There were fewer median infections in unvaccinated young   P Aaby et al – series of studies between 1995-2016 – BMJ, Vaccine, J Tropical Medicine Some vaccines (especially DTP) associated with higher all cause mortality in low income settings compared to those who did not receive DTP  

Anger, Taming The Beast Within “Anger is not a flaw of the spirit but a flare from the soul, signaling where healing waits to begin.” — Gary Null, PhD   $21 Trillion Dollars Is Missing From the U.S. Government. That Is $65,000 per Person—As Much as the National Debt!   The Solari Report Jan 01, 2026     What's going on? Where is the money? How could this happen? How much has really gone missing? What would happen if a corporation failed to pass an audit like this? Or a taxpayer?   This means the Fed and their member banks are transacting government money outside the law. So are the corporate contractors that run the payment systems. So are the Wall Street firms who are selling government securities without full disclosure. Would your banks continue to handle your bank account if you behaved like this? Would your investors continue to buy your securities if you behaved like this? Would your accountant be silent? This is the reason that there is such a strong push to change or tear up the U.S. Constitution. This is why members of the establishment say the Constitution is “old,” “outdated!” This is why there is such a push for gun control. Don't buy it! We can use the Constitution to get our money and our government back. It is time to enforce the U.S. Constitution. The Solari Report has been covering the missing money since 2000 when Catherine Austin Fitts began to to warn Americans and global investors about mortgage fraud at the U.S. Department of Housing and Development (HUD), and the engineering of the housing bubble that led to trillions more dollars in bailouts and funds missing from the U.S. government starting in fiscal 1998. missingmoney.solari.com   “[T]he powers of financial capitalism had another far-reaching aim, nothing less than to create a world system of financial control in private hands able to dominate the political system of each country and the economy of the world as a whole. This system was to be controlled in a feudalist fashion by the central banks of the world acting in concert, by secret agreements arrived at in frequent private meetings and conferences. The apex of the system was to be the Bank for International Settlements in Basel, Switzerland, a private bank owned by and controlled by the world's central banks which were themselves private corporations.” ~ Carroll Quigley, 1974  

HEALTH NEWS   Two days of oatmeal reduce cholesterol level  Walking for 150 minutes per week associated with improved wellbeing in over-50s Common Plastic Chemical Found To Feminize Males and Masculinize Females Colon cancer now top cancer killer for Americans under 50, study finds Long-term physical inactivity linked to higher stress burden in midlife  

HEALTH NEWS The mechanism of black ginseng extract in alleviating inflammatory aging Eating the Wrong Carbs May Raise Your Dementia Risk Mix of different types of physical activity may be best for longer life Oral bacterium may promote breast cancer development and spread Severe vitamin D deficiency linked to higher hospitalizations for respiratory tract infections

How to Repurpose and Restart Your Life When Your Current Path No Longer Works Gary Null PhD At some point, every person who wants a meaningful life must do something most people avoid: stop. Stop long enough to turn off the distractions and ask, with real seriousness, what the purpose and meaning of this life is. Then comes the harder follow-up: am I honoring that purpose—or am I merely performing a routine that looks like living? And if I'm honest, which pieces of my life no longer make sense to me?

The Second Part of How to Overcome Our Addictive Behavior: The Thirteenth Step 

HEALTH NEWS   Vitamin C plus Grape Seed Extract Outperforms Chemotherapy for Tumor Reduction Salted foods may increase cancer risk: Japanese study Why a life-threatening sedative is being prescribed more often for seniors Blueberry Drink Protects Mice from Diabetes, Obesity Microplastics Can Rewire Sperm, Triggering Diabetes in the Next Generation

How to Overcome Our Addictive Behavior: The 13 th Step. “All crises show us what we've avoided.” —Gary Null, PhD Today we're dealing with tens of millions of Americans who suffer from some form of addictive behavior.

HEALTH NEWS   Probiotics emerge as a potent tool against depression and anxiety Altered microbiome: Oral bacteria play a role in chronic liver disease, study reveals Health issues linked to cosmetic jab complications From yoga to awe walks: Many paths lead to better mental health, largest analysis of well-being interventions finds Weight loss drugs may cause nutritional deficiencies without proper guidanc       Probiotics emerge as a potent tool against depression and anxiety University of Calgary (Canada), January 14 2026 (Natural News) For decades, the standard pharmaceutical approach to treating depression and anxiety has dominated treatment options, despite significant drawbacks including delayed effects, debilitating side effects and high relapse rates. Now, compelling new research is challenging this paradigm by pointing to a surprising source of relief: the gut. A comprehensive scientific analysis, synthesizing data from over 1,400 clinically diagnosed patients, reveals that probiotics—beneficial bacteria readily available as supplements—can produce substantial reductions in both depressive and anxious symptoms.   The analysis major findings include:     A major analysis of 23 clinical trials finds probiotics can significantly reduce symptoms of depression and anxiety in clinically diagnosed patients.   The benefits, appearing within 4-8 weeks, were comparable to some conventional antidepressants but without the same side-effect profile.   The gut-brain axis, a communication network largely ignored by conventional psychiatry, is central to understanding this connection.   Single-strain probiotic supplements, particularly certain Lactobacillus and Bifidobacterium species, showed the strongest mental health effects.   This research supports a holistic view of mental wellness, where gut health is a foundational component of treatment.     Altered microbiome: Oral bacteria play a role in chronic liver disease, study reveals Technical University Munich (Germany), January 15 2026 (Medical Xpress) Each year, more than two million people die from advanced chronic liver disease (ACLD). Previous research has linked gut microbiome disruptions to this condition and suggested that bacteria typically found in the mouth may colonize the gut. A new study published in Nature Microbiology now shows that identical bacterial strains occur in both the mouth and gut of patients with advanced chronic liver disease and also reveals a mechanism by which oral bacteria affect gut health. The researchers also found that this process coincides with worsening liver health. Researchers analyzed bacterial populations in saliva and stool samples from patients. The team found that both the gut and oral microbiome undergo significant changes as liver disease worsened, where changes to the oral microbiome were already detectable at earlier disease stages. In healthy individuals, bacterial communities differ substantially between body sites. In patients with liver disease, however, oral and gut microbiomes became increasingly similar as the disease progressed and nearly identical bacterial strains were recovered from the mouth and gut of patients. "These strains are typically found in the mouth and are rarely present in the healthy gut. However, we observed increases in the absolute abundances of these oral bacteria in patients with advanced chronic liver disease. This strongly suggests that these bacteria translocate from the mouth and colonize the gut," explains Melanie Schirmer, Professor of Translational Microbiome Data Integration at TUM.   Health issues linked to cosmetic jab complications Anglia Ruskin University (UK), January 9 2026 (Eurekalert)   Patients with chronic illnesses face a significantly higher risk of complications from cosmetic botulinum toxin injections, commonly known as Botox, according to a major UK study. Researchers from Anglia Ruskin University (ARU) surveyed 919 adults who had received botulinum toxin treatments for aesthetic reasons. The study, published in Aesthetic Surgery Journal, is the largest of its kind to have been carried out in the UK. Botulinum toxin injections are among the UK's most popular cosmetic procedures, with an estimated 900,000 treatments performed every year. Researchers found that underlying conditions such as type 1 diabetes, thyroid disorders, chronic migraine and skin disease dramatically increase the likelihood of adverse effects. According to the study, people with type 1 diabetes were 92 times more likely to experience nausea after treatment compared to those without the condition. Those with thyroid disorders and chronic migraine sufferers had an approximately 10-fold increase in the risk of nausea. Other complications associated with pre-existing conditions included headaches, bruising, muscle weakness and persistent eyelid droop (ptosis). Patients with cataracts were 30 times more likely to report headaches, and those with prior injuries had a 21-fold increased risk of losing facial expression.   From yoga to awe walks: Many paths lead to better mental health, largest analysis of well-being interventions finds Swansea University (UK), January 15 2026 (Medical Xpress) New research by Swansea experts has provided the largest ever comparison of well-being-focused interventions delivered to adults. The team reviewed 183 randomized controlled trials, representing almost 23,000 participants, and evaluated 12 categories of interventions ranging from psychological, physical, mind–body, and nature-based approaches to find out more. Their research was the first interdisciplinary comparison carried out across psychological, physical, mind-body and environmental interventions. The study gives an integrated view of how different disciplines contribute to well-being. By focusing on general adult samples rather than clinical groups, it provides evidence that will be relevant to developing public health, education, workplace well-being, and community programs. The researchers' key findings were: Most interventions improved well-being compared with inactive control groups; Strongest effects were found for combined exercise plus psychological interventions (for example, awe walks or meditation combined with walking); Mind–body interventions showed consistently moderate, reliable effects; Exercise alone produced similar benefits to many psychological interventions; and, Positive psychology interventions—both single-component and multicomponent—were also effective. The analysis shows that there is no single route to improving well-being. Mindfulness, compassion-based approaches, yoga, exercise and positive psychology interventions all showed moderate benefits compared with control groups, and combining physical activity with psychological interventions appeared particularly promising.   Weight loss drugs may cause nutritional deficiencies without proper guidance     University College London & Cambridge, January 7 2026 (News-Medical) People prescribed the new generation of weight loss drugs may not receive sufficient nutritional guidance to support safe and sustainable weight loss, leaving them vulnerable to nutritional deficiencies and muscle loss, say experts at UCL and the University of Cambridge. In research published today in Obesity Reviews, the team found a lack of robust evidence surrounding nutritional advice and support and the impact this has on factors such as calorie intake, body composition, protein adequacy, and patient experiences. Weight loss drugs such as semaglutide and tirzepatide – available under brand names including Ozempic, Wegovy and Mounjaro – mimic the naturally-occurring hormone glucagon like peptide-1 (GLP-1), released into the blood in response to eating. The drugs suppress appetite, increase a feeling of being full, and reduce food cravings. These drugs can reduce calorie intake by between 16-39 %, making them a powerful tool to help people living with obesity and being overweight. However, there has been little research to examine their impact on diet quality, protein intake, or adequacy of micronutrients (vitamins and minerals). The researchers identified just 12 studies that looked at nutrition and diet alongside treatment with semaglutide or tirzepatide. Given the widespread – and increasing – use of these medications and the urgency of providing advice to individuals using the drugs, there was insufficient evidence from the studies to recommend strict low-fat diets to complement the weight loss drugs. Some observational studies found that people on the treatments often consumed excessive levels of total and saturated fat. These medications are transforming obesity care, but we know very little about how they shape people's daily lives, including changes in appetite, eating patterns, wellbeing, and quality of life.

HEALTH NEWS   Can exercise turn back the clock on your brain? New study says yes Why leaving things unfinished messes with your mind Short-term, calorie-restrictive diet improves Crohn's disease symptoms Higher daylight exposure improves cognitive performance, study finds Breastfeeding may lower mums' later life depression/anxiety risks for up to 10 years after pregnancy     Can exercise turn back the clock on your brain? New study says yes AdventHealth Research Institute, January 13 2026 (Eurekalert) A simple, steady exercise routine may help your brain stay biologically younger, supporting clearer thinking, stronger memory, and a greater sense of whole-person well-being.   The study found that adults who followed a year-long aerobic exercise program had brains that appeared nearly a year “younger” than those who didn't change their activity levels.   Published in the Journal of Sport and Health Science, the study explored whether regular aerobic exercise could slow, or even reverse “brain age,” a magnetic resonance imaging (MRI)-based biomarker of how old your brain looks compared to your actual age. A higher brain-predicted age difference (brain-PAD), indicates an older-appearing brain and has been linked to poorer physical and cognitive function and increased risk of mortality in previous research.  In this clinical trial, 130 healthy adults aged 26–58 were randomly assigned to either a moderate-to-vigorous aerobic exercise group or a usual-care control group. The exercise group completed two supervised 60-minute sessions per week in a laboratory plus home-based exercise to reach about 150 minutes of aerobic activity per week, aligning with the American College of Sports Medicine's physical activity guidelines. Brain MRI and cardiorespiratory fitness, measured as peak oxygen uptake (VO2peak), were assessed at the beginning and end of the 12-month period.  Over 12 months, participants in the exercise group showed a measurable reduction in brain age, while the control group showed a slight increase. On average, the exercise group's brain-PAD decreased by about 0.6 years, indicating a younger-appearing brain at follow-up. In contrast, the control group's brains appeared about 0.35 years older, a change that was not statistically significant. Overall, the between-group difference in brain age was nearly one year, favoring the exercise group.     Why leaving things unfinished messes with your mind Yale University, January 12 2026 (Medical Xpress) In a new study, published in the Journal of Experimental Psychology: General, Yale professor of psychology Brian Scholl and lab members explored why humans so badly want to finish what we've started—in matters great and small. It turns out the brain just doesn't like dangling threads. The researchers had a hunch that visual clues could help explain the lure of the unfinished. Why is this state of leaving things undone so salient to us? It's an interesting quirk of human nature that science has not previously addressed. Unfinishedness has been found to decrease work satisfaction, impair sleep, and fuel ruminative thinking patterns. The researchers turned to the visual system. When we see unfinished events, are they somehow prioritized in memory?" To test their hunch that visual memory plays a role in making unfinishedness feel so sticky, the researchers ran four experiments involving a total of 120 participants who viewed computer animations of simple mazes populated by moving dots or lines. In several experiments, it seemed that the brain is wired to notice and remember incomplete things better than finished ones. The findings suggest that "unfinishedness" isn't just about motivation or satisfaction. It's built into the way people see and remember the world.   Short-term, calorie-restrictive diet improves Crohn's disease symptoms     Stanford University, January 13 2026 (News-Medical)   There have been few large studies of dietary interventions for IBD, a group of disorders that includes ulcerative colitis and Crohn's disease. Now a Stanford Medicine-led study finds a short-term, calorie-restrictive diet significantly improved symptoms. Their national, randomized controlled clinical trial found that a short-term, calorie-restrictive diet significantly improved both physical symptoms and biological indicators of mild-to-moderate Crohn's disease. A chronic condition affecting about a million Americans, Crohn's disease causes inflammation in the digestive tract, leading to symptoms of diarrhea, cramping, abdominal pain and weight loss. Steroids are the only approved therapeutic for mild Crohn's, but their use is limited due to significant side effects, particularly with long-term use. The study compared the symptoms and biological indicators of patients with mild-to-moderate Crohn's disease as they either followed a fasting mimicking diet or ate their normal diet for three consecutive months. The study enrolled 97 patients across the country, with 65 in the fasting mimicking group and 32 in the control group. Participants in the fasting mimicking group severely limited their calories for five consecutive days per month, eating between about 700 and 1,100 calories a day. Plant-based meals were provided during the fasting period. For the remainder of the month, the fasting mimicking group ate their normal diet. At the end of the study, two-thirds of the fasting mimicking group experienced improvement in their symptoms. The researchers found a significant decline in fecal calprotectin, a protein in the stool that indicates gut inflammation, in the fasting mimicking group compared with the control group. Some inflammation-promoting lipid mediators derived from fatty acids also declined in fasting mimicking group participants. Similarly, the immune cells of fasting mimicking group participants produced fewer of several types of inflammatory molecules.   Higher daylight exposure improves cognitive performance, study finds University of Manchester (UK), January 12 2026 (Medical Xpress) A real world study led by University of Manchester neuroscientists has shown that higher daytime light exposure positively influences different aspects of cognition. The first study of its kind showed that stable light exposure across a week and uninterrupted exposure during a day had similar effects. Participants in the study experienced improved subjective sleepiness, the ability to maintain focused attention and 7-10% faster reaction speeds under bright light when compared to recent dim conditions. Compared with their peers who went to bed later, participants with earlier bedtimes tended to be both more reliably wakeful under bright morning light and sleepy under dimmer evening light. Being exposed to bright, stable daytime light was linked to enhanced and more sustained attention in a visual search task in which participants were asked to find a specific target on a page. Higher daytime light exposure and fewer switches between light and dark were linked to improved cognitive performance. And higher daytime light exposure and earlier estimated bedtimes were also associated with stronger relationships between recent light exposure and subjective sleepiness. However, neither the time of day nor time awake significantly impacted cognitive performance; the effect of light was stronger than the effect of time of day.   Breastfeeding may lower mums' later life depression/anxiety risks for up to 10 years after pregnancy University College Dublin (Ireland), January 8 2026 (Eurekalert)   Breastfeeding may lower mothers' later life risks of depression and anxiety for up to 10 years after pregnancy, suggest the findings of a small observational study, published in the open access journal BMJ Open. The observed associations were apparent for any, exclusive, and cumulative (at least 12  months) breastfeeding, the study shows. The researchers tracked the breastfeeding behaviour and health of 168 second time mothers who were originally part of the ROLO Longitudinal Birth Cohort Study for 10 years.   At the check-ups, the mothers provided information on: whether they had ever breastfed or expressed milk for 1 day or more; total number of weeks of exclusive breastfeeding; total number of weeks of any breastfeeding; and cumulative periods of breastfeeding of less or more than 12 months.   The study concludes there may be a protective effect of successful breastfeeding on postpartum depression and anxiety, which in turn lowers the risk of maternal depression and anxiety in the longer term.

HEALTH NEWS   Can exercise turn back the clock on your brain? New study says yes Why leaving things unfinished messes with your mind Short-term, calorie-restrictive diet improves Crohn's disease symptoms Higher daylight exposure improves cognitive performance, study finds Breastfeeding may lower mums' later life depression/anxiety risks for up to 10 years after pregnancy  

The Meaning of True Love

Rediscovering Purpose in the Age of AI

The Rewards of Risk What are you willing to risk? This is not a rhetorical question. It is one of the most important questions you will ever ask yourself, because your answer determines the size, texture, and vitality of your life.

Choosing Not to Fit In When I first came to New York, I worked briefly at a Fortune 500 company. It did not take long for me to realize that I could never work in a large corporation. I did not fit in—and I did not want to. I would rather take a chance, even risk unemployment, than surrender my autonomy. I do not fit comfortably in corporate America, government, industry, or even most movements. I may believe in a movement's goals, but I rarely trust its leadership. Too often, ego replaces balance. That clarity has shaped my life.

Living From Today Forward

Positive Defiance Creates the Freedom to Be Yourself

Your Daily Cup of Tea Could Help Fight Heart Disease, Cancer, Aging, and More

Gary's update to Overcoming The Dark Side

HEALTH NEWS   Naturally occurring molecule shown to restore memory function in Alzheimer's models Exercise helps breast cancer survivors maintain bone density Too Much Night Light? It Could Be Hurting Your Heart Curcumin inhibits pituitary tumor cell proliferation, induces apoptosis How certain gut bacteria drive multiple sclerosis

Alzheimer's disease can be reversed in animal models to achieve full neurological recovery.

Scientists map how cinnamon's bioactives interact with cancer signaling

Manifesting a beautiful life does not begin by acquiring more. It begins by appreciating what already exists. Gary Null, PhD

Vitamin D Could Prevent 30,000 Cancer Deaths Per Year in Germany Alone.    

On Today's show, Gary Null discusses the importance of making informed health choices to prevent diseases such as cancer, heart disease, and diabetes. He emphasizes the role of glycation in promoting arterial stiffness and its implications for aging and health. Gary advocates for natural remedies and lifestyle changes to reverse biological aging and improve overall health outcomes. He shares insights from clinical studies and personal experiences, encouraging listeners to take control of their health and make positive changes.

Melatonin shows promise as adjunct therapy for systemic lupus erythematosus, study finds Swapping high-carb snacks for tree nuts cuts food cravings in young adults at metabolic risk Reducing social isolation protects the brain in later life Exposure to PFAS and PCBs linked to higher odds of MS Two compounds sourced from cannabis show promising anti-cancer effects

The latest on health and nutrition and additional commentary from Gary

The Gary Null Show has been broadcasting for over four decades, making it one of the longest-running health and wellness programs. It began in the late 1970s, initially airing on traditional radio before transitioning to platforms like the Progressive Radio Network (PRN) and online streaming.  

A Nation Sublimating Its Rage — and the Consequences  

In this conversation, Gary Null discusses various health topics, focusing on the benefits of dark chocolate, the risks associated with alcohol consumption, and the connection between depression and the immune system. He challenges common beliefs in science and medicine, emphasizing the importance of lifestyle changes for mental health and overall well-being. The discussion also touches on nutrition's role in bone health and the need for a more engaged and informed public discourse on health issues.

Information and commentary on health & healing; Social and political issues also covered in depth. Dr. Gary Null is an internationally renowned expert in the field of health and nutrition, the author of over 70 best-selling books on healthy living and the director of over 100 critically acclaimed full-feature documentary films on natural health, self-empowerment and the environment.

Information and commentary on health & healing; Social and political issues also covered in depth. Dr. Gary Null is an internationally renowned expert in the field of health and nutrition, the author of over 70 best-selling books on healthy living and the director of over 100 critically acclaimed full-feature documentary films on natural health, self-empowerment and the environment.

Information and commentary on health & healing; Social and political issues also covered in depth. Dr. Gary Null is an internationally renowned expert in the field of health and nutrition, the author of over 70 best-selling books on healthy living and the director of over 100 critically acclaimed full-feature documentary films on natural health, self-empowerment and the environment.