Podcasts about Melatonin

Dr. Christopher Winter has been involved with sleep medicine and sleep research since 1993. Currently he is the owner of Charlottesville Neurology and Sleep Medicine clinic and CNSM Consulting. He is the author of The Sleep Solution: Why Your Sleep is Broken and How to Fix It as well as The Rested Child: Why Your Tired, Wired or Irritable Child May Have a Sleep Disorder – and How to Help. In addition to working with numerous professional sports organizations to help their athletes optimize sleep (including the reigning World Series champion Los Angeles Dodgers and NBA Champion Oklahoma City Thunder), he is the host of the podcast Sleep Unplugged with Dr. Chris Winter which has consistently ranked as one of the most popular medical podcasts in the country. SHOWNOTES:

In this episode, Blake interviews Dr. Frank Shallenberger, M.D., HMD, ABAAM, about the many health benefits of melatonin and how he uses high doses in his practice. Dr. Shallenberger is a Family Medicine Doctor at the Nevada Center for Alternative & Antiaging Medicine, Carson City, NV. He has been a pioneer in alternative/integrative medicine since 1978 and is one of only 16 physicians in Nevada licensed both in conventional and naturopathic medicine. Dr. Shallenberger has authored two books: The Type 2 Diabetes Breakthrough and Bursting With Energy and has authored numerous papers in the international peer reviewed literature on ozone therapy and oxygen utilization. You can find Dr. Shallenberger at https://antiagingmedicine.com/. You can watch all episodes of the Vibrant You Health Show at www.naturespantry.life. You can find the high-quality melatonin supplements mentioned in this interview at Nature's Pantry in La Grande and on our website.

Češi dnes spí o hodinu a půl až dvě méně než před sto lety a nějakou formou nespavosti trpí zhruba 40 procent populace. Neurolog David Pánek, který se dlouhodobě věnuje poruchám spánku, v Longevity podcastu Hospodářských novin vysvětluje, proč je důležitější pravidelné vstávání než hodina usnutí nebo kdy je v pořádku sáhnout po prášcích na spaní. „Melatonin je také vynikající věc, hodně pomáhá především u fázových posunů,“ říká Pánek a radí také, která látka funguje podle něj ještě lépe. V podcastu se dozví předplatitelé i o funkčních medicínských technikách nebo obyčejných fíglech, které mohou spánek vrátit.

Episode Highlights With KatieWhy light is the most important “nutrient” your body receives each dayHow natural light and darkness influence metabolism, hormones, gut health, and circadian rhythmHow blue light after dark affects melatonin, glucose, mood, and inflammationWhy sunrise light is nature's most important daily reset buttonThe difference between UV, visible light, and infrared ... and how each impacts biologyHow to align light exposure with your biology for better sleep, energy, and emotional regulationSimple, family-friendly ways to create a light-friendly homeThe 10 rules I personally follow (flexibly) to keep my circadian system alignedWhy light exposure is more foundational than diet or exerciseHow to start improving your light hygiene in just one dayResources MentionedFollow Peter Forhan on InstagramFollow Roudy Nassif on InstagramThe Light Body by Peter ForhanMy Circadian appBONCHARGEI like so many of their products - from their red light products to their sauna blankets. Red light has been so helpful for me during my recovery from Hashimoto's. To find out more, go to boncharge.com/wellnessmamaJust Thrive:Just Thrive Health has been one of my longtime favorite brands for gut health and they have an amazing Daily Gut Detox. Your immune system, gut barrier, and digestion get the support they need to stay strong and healthy. You can find this and their probiotics at justthrivehealth.com/wellnessmama or use code wellnessmama for 20% off your order. 

Jahrelang haben wir im Coaching gesagt: "Nach 18 Uhr nichts essen" ist kompletter Bullshit. Dann hat Josefine für ihren Ernährungs-Live-Call in die Forschung zu innerer Uhr und Insulinsensitivität geschaut. Und wir müssen zugeben: Ganz so einfach ist es nicht.In dieser Folge erklären wir, warum jedes Organ in dir eine eigene Uhr hat (dafür gab es 2017 den Nobelpreis), was Melatonin mit deinem Blutzucker macht und warum dieselbe Mahlzeit um 20 Uhr messbar schlechter wirkt als um 8 Uhr. Wir sprechen über die Harvard-Studie, die zeigt, dass spätes Essen hungriger macht. Über Schichtarbeit und ein 9 Prozent höheres Diabetesrisiko. Und über die Wechseljahre: Warum das Fett plötzlich zum Bauch wandert, warum bis zu 60 Prozent der Frauen dann schlecht schlafen und warum beides zusammen deine Insulinlage verschlechtert. Am Ende gibt es unsere ehrliche Hierarchie (Kalorienbilanz, Schlaf, dann erst Timing) und sechs Werkzeuge, die du ab morgen umsetzen kannst. Auch wenn du Schichtarbeit hast oder kleine Kinder.Support the show

In this episode of Revolution Health Radio, Chris takes a nuanced look at melatonin and challenges the idea that because it is a naturally occurring hormone, it is automatically safe for routine, long-term use. He explains melatonin's primary role as a circadian signal rather than a conventional sedative, explores concerns surrounding prolonged use and supplement quality, and examines recent research linking long-term melatonin use with heart failure risk—while emphasizing that observational research cannot establish causation. The episode also focuses on children, who may be particularly vulnerable to inappropriate or excessive melatonin use, and offers a foundational approach to better sleep centered on light exposure, consistent sleep schedules, stress regulation, sleep environment, and addressing underlying issues. The post RHR: The Melatonin Problem appeared first on Chris Kresser.

This week, we're rounding up a series of questions regarding children's books, including Goodnight Moon, Winnie the Pooh, Five Little Ducks, and Mr. Brown (of mooing fame). But first: some dream analysis. Join our Patreon!$1/monthAccess to the YDAFT Discord$4/monthAccess to the YDAFT Discord20% off all merch Access to our monthly bonus episodes..."Opps! All Tangents!" Go to https://www.patreon.com/youdidntaskforthis to become a member! Submit your least pressing questions, local legends, definitive rankings, neighborhood group drama, and whatever else you want us to cover at youdidntaskforthis@gmail.com or @udidntaskpod on TikTok, Instagram, Twitter, and Facebook.You can also leave us a voicemail on The Thoughtline at (410) 929-5329 and we might just play it on the show!

Tar du magnesium for å sove bedre og merker du egentlig forskjell? Kine og Espen deler ulike erfaringer med kosttilskudd og diskuterer melatonin, muskelkramper og behovet for magnesium. Vi tar også peptiddebatten: Hva skiller etablerte legemidler fra eksperimentell bruk, og når blir personlige erfaringer en anbefaling? Til slutt snakker vi om store treningsambisjoner, støtten hjemmefra og hva som gjør treningen meningsfull. .

Schlaf wird fast immer als Frage von Stress und Bildschirmzeit behandelt – dabei redet dein Abendessen kräftig mit. Wir schauen nüchtern auf die Studienlage: warum der Zeitpunkt deiner letzten Mahlzeit zählt, wie lange dein Nachmittagskaffee wirklich nachwirkt (länger, als du denkst) und warum der „Schlummertrunk" ein Mythos ist. Am Ende weißt du, welche paar Stellschrauben deinen Schlaf tatsächlich verbessern – ganz ohne Wundersnack.

Sleep plays a critical role in brain development, learning, memory, and behavior throughout childhood and adolescence. In this episode, Dr. Kristin Seaborg discusses how sleep architecture changes across development, the impact of sleep disorders on attention, headaches, epilepsy, and neurodevelopmental conditions, and why neurologists should routinely assess sleep in pediatric patients. Learn practical approaches to recognizing sleep problems, including obstructive sleep apnea and insomnia, and how improving sleep can enhance neurologic and cognitive outcomes. In this episode, Casey S. Albin, MD, FAAN, speaks with Kristin Seaborg, MD, author of the article "Sleep in the Developing Brain" in the Continuum® August 2026 Sleep Neurology issue. Dr. Albin is a Continuum® Audio interviewer, associate editor of media engagement, and an assistant professor of neurology and neurosurgery at Emory University School of Medicine in Atlanta, Georgia. Dr. Seaborg is an Assistant Professor in the Department of Neurology at the University of Wisconsin–Madison in Madison, Wisconsin. Additional Resources Read the article: Sleep in the Developing Brain Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @caseyalbin Guest: @KristinSeaborg  Full episode transcript available here Dr Albin: In neurology and life, we are all looking for the secret to being attentive, focused, and engaged, and we certainly want that for our children. And what if the answer to all of that was just in sleep?  Dr Jones: This is Dr. Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast.  Dr Albin: Hello, this is Dr. Casey Albin. Today I'm interviewing Dr. Kristin Seaborg about her article on sleep in the developing brain. This article appears in the August 2026 Continuum issue on the neurology of sleep. Welcome to the podcast, Dr. Seaborg. Thank you so much for being here. I learned a lot from your article. Can you just briefly introduce yourself to the audience?  Dr Seaborg: Sure. Thank you for having me. I'm thrilled to be here. My name is Kristin Seaborg. I'm a pediatric neurologist and sleep neurologist at the University of Wisconsin Medicine. I also run the pediatric sleep neurology clinic at UW Madison.  Dr Albin: That is the perfect person to be writing this article. And every time I read an article about pediatric neurology, I am just so struck that like little tiny humans are not small adults, that they actually have a totally different neurobiology. They are in different stages of development. And this was really a topic that I was not familiar with, and probably for most of our listeners, they're not familiar with as well. And so, I thought we'd maybe just start with some of the basics. What is going on in terms of like pediatric sleep architecture, and how is that different than the adult architecture that we might be m- more familiar with?  Dr Seaborg: Sure. So, a lot of us think that sleep is the thing we do that when, when we're not doing other stuff. But actually, it's completely the opposite. During sleep, our brain is learning and consolidating memory and cleansing what's happened during the day, and that's especially important during infancy and early childhood development, and as a child gets older. If we take infants for an example, fifty percent of their sleep is in a precursor of REM sleep, which we call active sleep, which is much, much more than adults, as opposed to adults have about thirty percent of their sleep in REM sleep. And also, infants need sleep like fifteen to seventeen hours a day. Not all of that is consolidated in one continuous period. They usually sleep over the course of the day, fifteen to seventeen hours, and that sleep time decreases over the course of childhood and adolescence as well.  Dr Albin: Yeah, it's amazing that there's so much more going on. As someone who's had newborns, it feels like, oh my gosh, they're really just sleeping all day. They're not doing anything. But they're doing quite a lot, and that really is so much work for their developing brain. And then one of the things that also really struck me about the article is that as children move from infancy through adolescence, not only is the sleep architecture changing, but the time they go to sleep, the amount of sleep they need, some of the pathology that they may develop, it changes throughout these early years of their life. And so maybe when we are thinking about what patients might come to the clinic with, I assume a lot of parents are kind of concerned like, "Is my child getting enough sleep? Are they sleeping the normal amount? Are they sleeping in the timeframe that would be normal?" Walk us through just in broad strokes, like what is a normal amount of sleep as you go through that pediatric developmental phase?  Dr Seaborg: So that's not a one-sentence answer. And there's a table in the Continuum article.  Dr Albin: Love that.  Dr Seaborg: So, infants sleep like fifteen to seventeen hours, and it's chunked out over the course of the day. Usually they have one consolidated sleep period at night, but then two to three naps during the day. And as you move through early childhood, toddlers and adolescents usually need about fourteen hours of sleep around the time they're one year of age. As they get a little bit older, then they need like eleven to thirteen hours, depending on the child themselves. And then as we move toward like school age, like eight to ten hours of sleep is usually adequate, but especially younger school children need about ten hours of sleep at night. And then the interesting thing that happens in adolescence and early teenage years is that kids need just as much sleep, but they actually naturally fall asleep later because their melatonin is released later. So, it feels like they need to sleep all the time, but actually they just go to sleep later, and when school comes, it's not time or doesn't feel ready for them to wake up. So, adolescents and teens also need about eight to ten hours of sleep a night.  Dr Albin: Right. And I just was struck, you know, we think about it in this article and these issues, we've thought a lot about, I think it'll come up in other podcasts, the importance of daylight savings time and how that actually really is not good for our brains. And I feel so much for these teenagers who are really at a disadvantage because we make them get up early to participate in the world when it's not really aligned with how their natural sleep cycle is, and it feels unfair.  Dr Seaborg: It does. And there's so much to that. So, adolescents have school, and then a lot of time they have like after-school activities, whether that's sports or theater or music or whatever, but that usually happens after school. And then the reality of today's society is they come home, and at least my teenager disconnects or kind of decompresses by looking at her phone forever. And a lot of teenagers and adolescents bring their phone to bed. That exposure to light right up until the time when they want to go to sleep really can disrupt their circadian rhythm too. So they have the natural delayed circadian rhythm, and then they have these lifestyle exposures between activities after school and screens and everything else that really make sleep onset difficult. And so, waking up for school at 6:00 or 7:00 in the morning is really difficult for them.  Dr Albin: Gosh, I feel for that. And I suspect that many patients are coming into the sleep clinic with that exact sort of like my early teen, my preteen, my teenager. They're just exhausted all the time, but they won't fall asleep. They're developing insomnia. It sounds like there's a lot of behavioral changes that need to go along with that. Is that what you're seeing?  Dr Seaborg: Yeah. So, I'm also seeing an kind of a corollary, a lot of kids that come in with headaches because they're not sleeping enough, and they feel awful, or they're coming in with difficulty focusing in school or cognitive fog because they're not sleeping enough, and that they don't always know that that's the chief complaint. But often, as you start asking sleep-related questions, you figure out exactly what's going on. So, their amount they're sleeping and kind of their natural sleep cycle is affecting everything about their life.  Dr Albin: Yeah. It just-- it really struck me that, you know, one of the things that you talk about in the article is that there is, in patients who have neurodevelopmental differences and disorders, they may specifically have some sleep impairment, and they have a neurobiological reason for those sleep changes. But also, like you're saying, sometimes these inattentions or what's diagnosed as ADHD is actually just because they are not sleeping well, and they can't focus. And I imagine that's really hard to tease out. Like, is there something when you're trying to tease that out in the clinic that helps you figure out, is it the dog wagging the tail or the tail wagging the dog?  Dr Seaborg: Sure.  Dr Albin: Which is coming first? Is it, is it really a neurobiology problem where they have nerve developmental disorders and therefore sleep problems, or they have sleep problems causing the symptoms of a nerve developmental disorder?  Dr Seaborg: So, there's so many ways to answer that question. The very first part is you start at the beginning, not only asking the person's chief complaint, like, "Are you having trouble with attention?" But then also, uh, like I'll say, "Okay, what time do you go to sleep?" But not only that, "What are you doing before bedtime?" And then once they're asleep, are they snoring? Are they waking multiple times at night, you know, without trying to? And when they wake up in the morning, do they feel refreshed, or do they really still feel like they could fall asleep for a very, very long time? And then with regards to the neurodevelopmental disorders, it's fascinating. A lot of kids with neurodevelopmental disorders, whether that's ADHD or autism spectrum disorder or a genetic disorder that causes a developmental difference, often some of the pathophysiology of the actual neurodevelopmental difference also impacts the circadian rhythm and melatonin release and the brain's ability to initiate and maintain sleep. So, it's really important as a provider to be cognizant if you're seeing your patient with autism or ADHD to also ask about their sleep-related symptoms. And then eventually you'll ferret it out, but it takes a lot of sleuth work and investigation.  Dr Albin: So, what I'm hearing is actually when people come in with a chief complaint that probably is not like, "Hey, I'm having trouble sleeping," but maybe, "I can't focus" or, "I have headaches," or I have other problems that are being referred to a neurologist or pediatric neurologist, it really does behoove us to pause and take a good sleep history on all children coming in.  Dr Seaborg: Yes, and I'm gonna piggyback on that. Also, very, very important for our patients with epilepsy. There's a super high coincidence with epilepsy and sleep disorders, and there's actually been direct comparisons with children that-- typically developing children and children with epilepsy that's poorly controlled, and the amount of sleep-related complaints and sleep-related symptoms they have is astronomically higher. So, it's important as a neurologist to always have sleep kind of on our front burner, something we're paying attention to.  Dr Albin: No, it's so true. You know, I learned a lot about pediatric sleep and epilepsy through the article, and I think that obviously we wanna refer the listeners to checking out a little bit more. But there were a couple of things that were new terms to me that maybe others are not familiar with, and it does relate to like they are epilepsy, but they are more nocturnal, and they have more nocturnal epilepsies that we might need to really think and consciously consider. So, the new terms for me were SeLECTS, which I assume is actually just said as SeLECTS, but stands for... You tell me, what does it stand for?  Dr Seaborg: Self-limited epilepsy with central temporal spikes.  Dr Albin: Perfect. So okay. So, let's just start with that. Like, what is going on there? What do I need to know about it?  Dr Seaborg: So, SeLECTS was previously known as benign rolandic epilepsy 10 to 20 years ago, and then that, the term evolved to childhood epilepsy with central temporal spikes. But then it evolved again to SeLECTS, which is self-limited epilepsy with central temporal spikes. I think the primary motivation of changing the terminology, at least initially, was to acknowledge that even though this type of epilepsy occurs during childhood and it's self-limited, it is not benign always because seizures can cause some daytime dysfunction, and also there has been some association with ADHD-like symptoms or learning disability symptoms later in life. The other term you just mentioned, developmental epileptic encephalopathy with spike wave activation in sleep. That's a mouthful. That's the new terminology for what we used to call ESES or electrical status epilepticus of slow wave sleep. So, DEE-SWAS, developmental epileptic encephalopathy with spike wave activation in sleep is a broader term to encompass a bunch of epilepsy syndromes that have spike wave activation that during sleep, it is associated with developmental delay and per-perhaps developmental regression.  Dr Albin: And is that typically seen early childhood infancy? Like, I think of that as being something that you're gonna encounter really early in the life cycle. Am I correct?  Dr Seaborg: Not always. Sometimes, like school-aged children, one of the classic presentations is what it can be known as Landau-Kleffner syndrome, where you have spike wave activation during sleep in a, a school-aged child at like between the ages of six and 10, and then they have language regression, and you look at their EEG overnight and you see that they have epileptiform activity for up to 85 to 95% of the night.  Dr Albin: Wow. So, I wanna drill down on this. Since both of these things may come up, and probably are not something that the family is coming to you and saying, "Hey, I've seen these bizarre things happen in sleep," but are coming with daytime symptoms, how is it that you decide who is going to need a pediatric sleep study?  Dr Seaborg: Great question. So, if a child ever or a parent ever comes and complains or with concerns of developmental regression, and I guess I'm biased cause I'm a sleep doctor, but I would always do an EEG recording overnight if there were any concerns. And then if patients come and they just talk about rhythmic movements at night or waking up at night with some facial twitching, or the next day they're really acting tired, then I would order a sleep study. And of course, I would always ask the typical questions: Are they snoring? Are they waking up with a headache or not well refreshed? And ask a little bit more about a sleep history. But developmental regression and rhythmic movements at night definitely should be studied.  Dr Albin: And those questions about, you know, snoring at night, waking up with a headache, you're trying to get to pediatric obstructive sleep apnea. Is that right?  Dr Seaborg: Correct. Yes. Thank you for clarifying.  Dr Albin: Yeah. No, I just wanna make sure, like, because obviously that is a very common problem in the adult patient population. How frequently are you encountering that now in pediatric land?  Dr Seaborg: So actually, it's more common than you would think.  So kids have, especially kids that I'm seeing in the pediatric neurology clinic, sometimes have some different facial anatomy or enlarged tonsils or enlarged adenoids, or they have a primary genetic disorder that gives them a little bit different facial anatomy, and they're at much higher risk for obstructive sleep apnea. Kids with different muscle tone, whether they have cerebral palsy or a different kind of hypotonia disorder, are at very high risk of obstructive sleep apnea. And then kids with epilepsy, for reasons that we don't fully understand, are at higher risk for obstructive sleep apnea. So, it's actually quite common in children. We see it a lot.  Dr Albin: Wow, that's fascinating. And then I wanna just in our little limited time together, there were two other sort of neurodevelopmental disorders that came up in the article and I think are at least worth previewing for the listeners. So, autism spectrum disorder, obviously a very large and a range of how patients can present, but sleep really does seem to be a manifestation. Walk us through the association there.  Dr Seaborg: Sure. So, we don't know 100%, but I can give you a few statistics. For instance, 20 to 75% of kids with autism spectrum disorder have some sort of sleep onset or sleep maintenance insomnia or some primary sleep disorder, which is astronomically high. We all know the etiology of autism is multifactorial, and there's not just one gene or one difference that leads to autism, but there are a fair amount of genetic differences that sometimes can lead to a diagnosis of autism spectrum disorder. We've found there's kind of coincidence of some differences in some of the circadian genes. Specifically, time and clock are two of the circadian rhythm genes that have been shown to have higher incidence of differences in kids with autism spectrum disorder. And then kids with autism spectrum disorder also sometimes have some underlying anxiety or hyperactivity in it that also compounds their difficulty falling asleep and sometimes their difficulty staying asleep at night. And so, there's multiple things that are playing in that can make sleep difficult, which in turn can affect their daytime performance and their daytime regulation. So, lots going on there.  Dr Albin: Absolutely. I mean, in reading this, I was struck by, oh gosh, there's a lot of both pharmacological and sort of behavioral therapy that has to go into like readjusting and, and setting normative patterns and expectations. It sounds like melatonin can, in some cases, be helpful here.  Dr Seaborg: Yes, melatonin. So, I know there's a lot of patients will come to me, they're like, "I don't wanna use melatonin 'cause my Facebook group told me it was terrible." There's a lot of literature and a lot of recently published literature to show the safety and efficacy in low-dose melatonin, especially in children with neurodevelopmental disorders and specifically in kids with autism spectrum disorder. Melatonin is safe and okay to use. It's important to educate your patients though. So, a little bit works, and then a patient's kind of natural reaction is, "Oh, if a little bit is good, I'm just gonna give them more." But the more melatonin you give a person, actually the less their brain produces, and it's almost like a negative feedback. So, the studies support using two to five milligrams of melatonin one to two hours prior to bedtime to kind of stimulate melatonin release and then help with sleep onset. Melatonin does not help with sleep maintenance, but for the kids that are on the kind of neurodevelopmental disability or disorder spectrum, it really can help with sleep onset. Dr Albin: Yeah. I was really fascinated to hear that there is some more evidence for the extended-release formula. And is that something that you can just go onto Amazon and get the extended release or is that prescription?  Dr Seaborg: It's not prescription. You can 100% go onto Amazon and get the extended release. Immediate release melatonin will help with sleep onset, but then a lot of kids w- with brains that work differently wake up two to three hours later. The extended release can stick with you for a little bit longer.  Dr Albin: Well, there you go. I always love the things that you're just like, "All you gotta do is get on Amazon and it'll come to your house the next day." We all love a quick fix like that.  Dr Seaborg: Right.  Dr Albin: The other topic that came up is obviously patients with ADHD and, like, how their sleep really can both impact how they are performing and some of their symptoms of inattention, and may also sort of compound, you know, or, or be a, um, manifestation of the fact that there is a neuro biologic difference.  Dr Seaborg: Right. So, ADHD is an interesting kind of disorder, disability, or condition, um, because there's so many things that play into that. Sleep-related stuff, we've been residents before, and, you know, the longer that we're awake, actually the harder it is to focus and concentrate. Interesting, there have been some stereo EEG patients that they've shown that sleep is not the whole brain happening at once, but actually there are parts of the cortex that can ha- fall asleep in, like, micro-sleep or local sleep after prolonged periods of wakefulness even while you're awake. So, it can look like you're inattentive, but literally part of your cortex is falling asleep. So, these patients that have been awake for forever or had prolonged periods of wakefulness can look like they have inattention, but actually they're just sleeping poorly. I see this a lot in kids that have previously undiagnosed obstructive sleep apnea or previously undiagnosed periodic limb movement disorder. The parents come with a chief complaint of inattention or difficulty focusing, and then the sleep studies show that their sleep is very disrupted, and we treat OSA, and all those symptoms are better. Conversely, kids with ADHD, so the neurobiology of ADHD, the neurotransmitters that are implicated in ADHD that kind of regulate wakefulness are also different, so, like, norepinephrine and epinephrine and stuff like that. So, it makes falling asleep harder in kids with ADHD just because their genetic makeup and how kind of their brain and their biology is working. Insomnia is a common disorder in kids with attention deficit disorder.  Dr Albin: Wow. It's just amazing how integral sleep is to just the whole function. I'm not surprised because we certainly feel that having been residents. We, I think we all, as doctors, acutely know how bad it feels when you do not sleep well. We are coming to the end of our time. A lot of these questions that I had posed for you we've actually kind of answered, but I did want to give everyone who's listening in, and maybe they're in the car or cooking dinner, you might not have heard the snippet. This is just rapid-fire questions that you may encounter in neurology clinic or pediatric neurology clinic. Quick answers. My child snores. Is that normal?  Dr Seaborg: No. It's not normal, especially snoring and pausing. So, I, like, the guttural pauses. Never normal. That child should have a sleep study.  Dr Albin: Perfect. The Facebook group said that melatonin is not safe. What do you think?  Dr Seaborg: Low doses of s- melatonin are 100% safe and efficacy or efficacious, excuse me, in children. Um, but low doses. Two to five milligrams at the very most. If it's not working, use less. Don't add on more.  Dr Albin: Love that. My teen is up till midnight. Why?  Dr Seaborg: Unfortunately, your teen is normal, and their biologic clock is moved back as they approach adolescence, and their melatonin release is later. One thing you can do is make sure that the screens are out of the room two hours before bedtime, and that they have some downtime before bedtime.  Dr Albin: And then finally, a sleep study, that seems very intense. Can my child have that?  Dr Seaborg: Your child can 100% have a sleep study, especially the certified sleep centers are really good about dealing with kids that don't like all the sensors or the leads, and they can come in and readjust. I would highly recommend it. It's worth your time, especially cause it's a low-hanging fruit that we often can help.  Dr Albin: Love that. All right. Again, I've been interviewing Dr. Kristin Seaborg about her article on sleep and the developing brain. This article appears in the August 2026 Continuum issue on Neurology of Sleep. Be sure to check out Continuum Audio episodes from this and other issues, and thank you to our listeners for joining today.  Dr Monteith: This is Dr. Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

Der KI-Wettlauf - Wo steht Europa? ; Paper Mills oder wie Fake-Studien fabriziert werden ; Frauengesundheit - zeitnahe Diagnosen oft schwierig ; Vorsicht bei Melatonin als Einschlafhilfe ; Warum Forschende vor vereinfachten Zulassung von Pflanzenschutzmitteln warnen ; Rechenzentren als Wärmequellen ; Moderation: Marija Bakker Von WDR 5.

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Three of the leading causes of death—heart disease, cancer and metabolic illnesses—share a common underlying problem: mitochondrial dysfunction driven by excess oxidative stress and free-radical damage. Hosted on Acast. See acast.com/privacy for more information.

Child immune system support isn't about stopping every cold — it's about knowing which ones are normal. Nurse Doza breaks down how a school-age immune system actually develops, what's worth a closer look, and five things you can do at home: sleep, food, the right supplements, movement, and nervous system care. Plus the one nutrient that keeps coming back low on lab work. Featured Product The D (4-Month Supply) — $75 Vitamin D receptors sit on immune cells throughout the body — in the gut, the sinuses, the lungs — and vitamin D is one of the most commonly low results on a standard lab panel. The D pairs vitamin D3 (cholecalciferol) with vitamin K2 as MK-7 in a single daily capsule, and one bottle runs four months. One habit, one bottle, the whole season covered.

Discover the emerging science of quantum biology and how light, water, and connective tissue regulate human health from the inside out. In this episode, naturopathic physician Dr. Catherine Clinton joins the show to explore how frequencies of light—from morning blue light and soothing red rays to invisible infrared—directly charge our cells and influence circadian rhythms. Move beyond purely chemical and dietary models of health and learn how our body operates as an intelligent, interconnected network. Dr. Clinton explains the hidden role of fascia as a piezoelectric, liquid-crystalline communication system powered by structured water and infrared energy. Learn how light exposure impacts gut lining turnover, the gut microbiome, skin aging, and mitochondrial ATP production. What You'll Learn: The Electromagnetic Spectrum & Cellular Signaling: How visible colors, UV, and infrared light interact with retinal photoreceptors and skin chromophores. Circadian Entrainment for Gut & Hormone Health: Why morning natural light initiates cortisol and metabolic cascades, and why artificial night light disrupts melatonin and enterocyte renewal. Red Light & Collagen Synthesis: How red and near-infrared wavelengths stimulate fibroblast mitochondria in the fascia to support wound healing and smooth fine lines. Fascia as a Quantum Conduction Network: The science of collagen nanotubes, piezoelectric charges, and Dr. Gerald Pollack's research on structured water acting as a biological battery. Practical Mitochondrial Care: Accessible protocols including hydration, gentle stretching, sauna, red light application to the abdomen, and mindful intention. Timestamps & Chapters [00:00] – Start [00:04] – Introduction: The physiological and psychological impact of colors [02:09] – The electromagnetic spectrum: Ultraviolet, visible light, and infrared [04:10] – Morning sunlight, circadian rhythms, and setting your cortisol cycle [06:03] – Red and green light therapies: Pain relief, circulation, and mitochondrial ATP [08:47] – Red light for skin health: Fibroblasts, fascia, and collagen production [11:17] – Moving beyond chemistry to a quantum biological model of medicine [12:00] – Ultraviolet (UV) and blue light: Antimicrobial properties and skin balance [13:03] – Circadian regulation of enterocytes and gut barrier repair [16:12] – Melatonin, evening light, and the gut-microbiome-mitochondria triad [17:06] – Non-invasive abdominal light therapy for GI and autoimmune support [19:27] – The bidirectional skin-gut connection and microbial signaling [24:48] – Understanding fascia: Connective tissue, collagen triple helix, and nanotubes [26:06] – Piezoelectricity: Generating electrical charges through fascia movement [27:09] – Structured water (EZ water), hydrophilic surfaces, and infrared energy [28:36] – The biological "water battery" and quantum proton conduction [31:46] – Fascia stretching research and cellular resilience [33:20] – Practical ways to support fascia: Hydration, gentle movement, and infrared exposure [35:15] – The mind-body connection: How meditation and mindset nurture mitochondria [36:40] – Dr. Catherine Clinton's #1 daily gut health practice

Light is one of the most powerful signals regulating the body's internal clock, influencing sleep, hormones, metabolism, mood, and overall health. In this episode, we explore how morning light, daytime brightness, evening darkness, and nighttime habits can either strengthen or disrupt circadian rhythm. We also discuss practical ways to get your light right and honor the night in a world filled with screens and artificial illumination. Joining us is Dr. Deanna Minich, a pioneering nutrition scientist and thought leader with more than 25 years of experience bridging science, spirituality, and art; she serves as Chief Science Officer at Symphony Natural Health, is a Personalized Lifestyle Medicine Institute board member, and received the Institute for Functional Medicine's 2025 Linus Pauling Award.   Key Takeaways To Tune In For: (00:00) – Introducing Dr. Deanna Minich (03:16) – The Science of Time and Biological Age (07:44) – Melatonin and Circadian Rhythms (16:12) – Understanding Biological Rhythms (25:29) – Optimizing Your Daily Light Exposure (36:04) – Social Jet Lag and Healthy Aging   Resources talked about in this episode: Websites: DeannaMinich.com Social media handles: Facebook Instagram YouTube LinkedIn      

Insomnia is not just the absence of sleep, and this hypnosis to drift into deep sleep is built to remove negative blockage, restore natural melatonin release, and say goodbye insomnia for good. It finds that blockage, addresses it at its root, and clears the path to the deep, uninterrupted rest your body has been trying to reach.Through precise sleep induction hypnosis, Andrew works to remove the negative blockages... the accumulated stress, the subconscious resistance, the emotional residue that settles into the nervous system and quietly keeps the door to sleep from opening all the way. As those layers dissolve, your body's natural melatonin release begins to flow freely... not forced, not manufactured, but restored to the rhythm it always had before life got in the way.Goodbye insomnia. This session is here every night you need it. Explore Andrew's full library and let each session take you one layer deeper into the rest you were always meant to have.

Circadian rhythms influence far more than sleep, affecting neurologic disease expression, treatment response, and overall health. In this episode, Dr. Sabra Abbott discusses common circadian rhythm disorders, the health consequences of circadian misalignment, and practical strategies for managing jet lag, shift work, and disrupted sleep-wake schedules. Learn how circadian biology can shape neurologic outcomes and why considering the timing of behaviors, light exposure, and treatments may improve patient care. In this episode, Katie Grouse, MD, FAAN, speaks with Sabra M. Abbott, MD, PhD, author of the article "Circadian Neurology" in the Continuum® August 2026 Sleep Neurology issue. Dr. Grouse is a Continuum® Audio interviewer and a clinical assistant professor at the University of California, San Francisco in San Francisco, California. Dr. Abbott is an Associate Professor of Neurology at Northwestern University Feinberg School of Medicine in Chicago, Illinois. Additional Resources Read the article: Circadian Neurology Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Full episode transcript available here Dr Grouse: Circadian rhythm disruption affects many of our patients in far-reaching aspects of their general health and has likely personally affected most neurologists at some point in their career. Today, I have the opportunity to interview Dr. Sabra Abbott, who is the author of the latest issue of Continuum on Neurology of Sleep.  Dr Jones: This is Dr. Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast.  Dr Grouse: This is Dr. Katie Grouse. Today, I'm interviewing Dr. Sabra Abbott about her article on circadian neurology. This article appears in the August 2026 Continuum issue on Neurology of Sleep. Welcome to the podcast, and please introduce yourself to our audience.  Dr Abbott: Thanks for having me. I'm Dr. Sabra Abbott. I'm an associate professor of neurology at Northwestern, and I'm also director of our circadian medicine clinic.  Dr Grouse: It's really great to have you today. I definitely enjoyed reading your article, and not only did I learn a lot, but I feel like it's really applicable to a lot of topics that come up in clinic when I see patients. Now, I was wondering if you had to choose one key point that readers of your article would take away after reading it, what would it be?  Dr Abbott: I think the most important thing to keep in mind is that time is an important variable in every single thing that we do. And so, it can impact when your patient's disease is at its best and at its worst, and then it also can impact when it's actually most appropriate to provide medications for your patients. There can be times where they may be more impactful and times where they may actually cause more harm for your patients. So, the short answer is think about time always with your patients.  Dr Grouse: On that topic, I was really amazed to learn about the significant health risks associated with circadian misalignment, including even malignancy risks. Can you review some of these risks and why this might be the case?  Dr Abbott: So, I think the risk that we have the most data for is the risk for cancer associated with circadian misalignment, and this comes from a lot of studies that we're looking at patients who are shift workers. The data has actually come back on two separate reviews indicating that shift work could be a probable carcinogen, and we think that that probably comes down to a lot of different factors. So, when you're a shift worker, you are often working in the middle of the night. You may be getting light exposure at a time when you're normally producing melatonin, and that may be one factor that is actually putting you at increased risk for cancer.  Dr Grouse: And certainly, after reading this and hearing all of these things, I'm not surprised that many sleep specialists really dislike daylight savings time, which also is enough of a factor to potentially increase some of these health risks. Do you agree that daylight savings time is something that's contributing to poor health in our population?  Dr Abbott: So, I think it is definitely something that almost all of us want to get rid of, and I think where everybody is in agreement is that we should get rid of these shifts in the spring and the fall. I think the only benefit to those shifts that I see is it does create a time where we start having conversations about your circadian clock, so people become aware of circadian timing twice a year when we have these shifts. Outside of that, that shift back and forth seems to be very problematic. So, we do see both in the fall and the spring an increased risk for car crashes, an increased risk for heart attacks, stroke. People perform worse at work, and so I think in general, we probably should get rid of it. There's a little bit of a debate as to whether we should go to permanent standard time or permanent daylight saving time. I think most sleep and circadian scientists prefer permanent standard time. A lot of people who really like their evening activities prefer permanent daylight saving time, but I think that's also biased by the fact that daylight saving time, everybody has longer days, and I think they want longer days year-round, and you don't get that no matter which way you shift the clock in the winter.  Dr Grouse: That's really interesting. I do see that debate pop up every, I guess twice every year, and I guess there is a silver lining that at least we are all talking about it and thinking about it. I wanted to take a step back about the topic of circadian rhythm disorders in general. Could you just really quickly, like twenty-thousand-foot view, summarize what these main circadian rhythm disorders are?  Dr Abbott: So, at the moment, we primarily think of circadian rhythm disorders in the context of how they impact your sleep-wake timing. And so, at the largest level, we think of them as either intrinsic disorders, so disorders where your internal timing doesn't match up with the environment. The four key disorders there are advanced and delayed sleep wake phase disorders, so you're either earlier or later. You have non-twenty-four, where you actually generally get later and later each day, so it's like you're living on Mars. And then we have irregular, where you have multiple bouts of sleep that happen both night and day. And then the other two are the extrinsic disorders, so these are shift work disorders. So, you may have a normal functioning clock, but the external environment is forcing you to do things you wouldn't normally, or jet lag, where you again have a normal functioning clock, but then you end up having to shift multiple time zones faster than you can adapt to. Now, I think the interesting thing, and we can talk about this more if you want, is that we are moving into thinking of circadian rhythm disorders as being much more than just abnormalities of sleep-wake timing, and I think that's kind of where the future of the field goes.  Dr Grouse: Tell me more about that.  Dr Abbott: So, I think as the article gets into beyond just these kind of classically recognized disorders, we realize that circadian disruption can play a role in almost any other medical disorder that you can experience. And so, we can see circadian disruption as either a symptom or a potential cause of many other disorders. And then also in the optimal care of pretty much any patient, thinking about all of these other factors that they're experiencing on a day-to-day basis, whether it's their light exposure, whether it's the timing of their meals, whether it's the timing of their medications, all of those can play a role in their overall health and improving your ability to care for them.  Dr Grouse: Now, I did find it really fascinating. This was not something that I had really been aware of prior to reading your article about the fact that it really can make a difference about when you time particular medications for particular types of neurologic conditions just related to the circadian rhythm. And really interesting was the epilepsy connection. Can you tell me about how that affects how we should be dosing anti-seizure medication?  Dr Abbott: So, I think the epilepsy connection is an interesting one that definitely needs far more studies. So, at this point, a lot of this data is really coming from observational studies, looking at when patients have received medications and then how good their outcomes are. And in epilepsy, I think a lot of us tend to time anti-seizure medications so that patients get more of them in the evening and lower doses during the daytime. And I think a lot of this has been driven a little bit more by the fact that many of these medications are sedating, so we tend to put the more sedating medications at bedtime. But it turns out that outcomes in patients are actually better if they get higher doses at night and lower doses in the morning. Now, this is sort of theorizing at this point, but it could either be targets of these medications or your ability to uptake these medications across the blood-brain barrier may change with the time of day component. So, at this point, these are still really observational studies, but I think an area where we really need to do a lot more work.  Dr Grouse: Well, I look forward to hearing more about other ways that we'll learn how best to manage our medications for circadian rhythm function. Now, I wanted to ask, which circadian rhythm disorder do you think is the hardest to treat, and why would that be the case?  Dr Abbott: So, I'm gonna give you two answers to that. In terms of the primary circadian disorders that I see come through my clinic door, I would say cited non-24. These are patients who have normal vision, but they act as though they are living in a world without these external light time cues. And so, they, every single day, get a little bit later and a little bit later, and it's really, really hard to get them from a 25-hour schedule back onto a 24-hour schedule. The second part of my answer to that is shift work disorder, and those, I would say, are much more common patients to encounter. I think every single one of us, as we've gone through our medical training, has probably had some degree of shift work disorder, difficulty sleeping when we need to, staying awake during our shifts. But it's still really hard to figure out what we should be doing because, one, it's a multi-component system, so anything that I do to change your shift schedule has trickle-down effects to every one of your coworkers, and so we can't just tell one person, "Change what you're doing." It's also really hard to figure out what we should be doing. Should you only be working nights forever and ever and become purely nocturnal, and should we adapt everything to that, or we-- should we find some sort of compromise so that you can work the night shift but still have time to socialize and spend time with your family during the daytime? And how do we do all of that while still optimizing your health? And so, I think from a patient population, that is really a large problem we don't have a good answer to yet.  Dr Grouse: Sounds like it's something that you really have to customize to every single patient who walks in and their, their particular scenarios.  Dr Abbott: Absolutely.  Dr Grouse: Jet lag disorders is another circadian rhythm disorder that I think we all have had some personal experience with. Any tips or tricks on how to manage jet lag going east or west, or any resources that you recommend that can help us manage this, or we can advise to our patients?  Dr Abbott: Yeah. When we're talking about individualized, personalized treatment, I would say jet lag absolutely is way up there at the top of the list because it's not only a matter of where do you currently go to sleep and wake up in your current time zone, it is how many time zones are you going across to get to where you're going? Do you wanna keep the same schedule when you're at the new time zone? And all of these other factors in terms of how long you're gonna be there. When are you gonna come back? Does it make sense to fully adapt yourself to that new schedule? With that in mind, the general tips are if you are heading east, generally your goal is to shift everything earlier, and if you're heading west, generally the goal is to shift everything later. There are a lot of online calculators you can use where you can put in your current time zone, your destination time zone, and it will give you very specific information about when you should be getting light, when you should be avoiding light When melatonin may be helpful as another time cue that can help shift you. But again, it really depends on which direction and how many time zones and what time you're gonna arrive. I would say the practical tip that I have is whatever you do when you get to the new time zone, um, most of the time international travel involves overnight flights, so you may arrive in the morning. Resist the temptation to take a nap as soon as you arrive because that's just gonna make things harder and harder to adapt to. So, get out, be active, eat on the new time zone, try to push through that day, and then the homeostatic drive for sleep is gonna help you through that first night.  Dr Grouse: Great tip, and definitely a tip I have failed to follow in past trips and regretted greatly afterwards. There were some other really great points that you made that as an ambulatory neurologist I hadn't thought of that was really, really helpful, including when we take care of patients in the hospital, of course, we-- we're always careful about, you know, potential sort of things we can do to minimize delirium. But in fact, there's probably a lot of things we can do to minimize disruption to circadian rhythms, which we already know that if we're not careful about, can be deleterious to health. What are some things that you recommend generally for patients who are admitted regarding monitoring and treatment that we can try to do to mitigate that effect?  Dr Abbott: So, I would say the number one most important thing that you can do, and I did this every single day when I was on the wards, is when you walk into the patient's room for rounds in the morning, turn on the lights, open the curtains. We did an interesting study a few years ago because there was all of this discussion of nighttime disruption to hospital patients and a lot of concern that they were getting too much light and too much interruption to their sleep at night. But what we found out was actually the bigger problem may be that none of our patients are getting light during the daytime, and so they've just lost that amplitude of light rhythm. And so as much as you can maximize daytime and opening those curtains, turning on the lights, giving them a bunch of light during the day. And then obviously, on the opposite end, you wanna make sure that they're getting dark at nighttime. Being really thoughtful about what your patients actually need to have done while they're in the hospital. And so, do they really need to have vitals every four hours in the middle of the night? Is that gonna change their outcome, or are they just sitting there waiting for insurance to approve their rehab bed, and they're probably gonna be fine overnight without that disruption? I think those are the easy things that you can do. The slightly harder piece is there's a lot of debate about whether we really need to be doing four AM labs on all of our patients, for example. Obviously, that's disrupting everybody's sleep. It's making a phlebotomist be a shift worker. It's problematic in many respects, but at the same time, you need to collect the labs so the labs can actually be processed and you can have the results, and they can be available for rounds, and so you can discuss them so that then you can discharge the patient on time. And so, it's a whole set of moving parts that are sometimes a little hard to optimize specifically for the patient.  Dr Grouse: Certainly, worth a discussion to have, though, and all really great tips. Another question kind of on that same vein. A lot of patients ask for something to help sleep at night. Melatonin is something we often give as sort of an easy, relatively gentle treatment that can help with sleep. Do you agree that that's a good idea? Is that something that you would generally recommend?  Dr Abbott: So, I would say that melatonin on the overall risk versus benefit spectrum probably has very low side effects for your hospitalized patient. At the same time, we actually fought this battle here. On many of the hospital formularies, you have very high doses of melatonin, so it's five, ten milligrams. Now, the problem with that is it takes you long enough to metabolize that ten milligrams of melatonin that it is still gonna be in your system the next day. So, then you go to round on the patient the next day and they're groggy and they're out of it, and it may not be that they've neurologically deteriorated, it may still be that they have melatonin still in their system. So, if you are going to use that as sort of a first-line low-harm option, I would stick to one to three milligrams.  Dr Grouse: Great. One to three milligrams is something I've often heard. Is that generally optimal dose and timing for melatonin, uh, you suggest for patients, or how do you approach thinking about the dose and timing?  Dr Abbott: So, this is where it gets a little more complicated because we actually don't recommend using melatonin as a general hypnotic. It's not that great for treating insomnia in general. So, where we do more often use melatonin in circadian patients is as a phase-shifting stimuli. So, this is something that if you give melatonin at a specific time, it can either move your clock earlier or move your clock later. And that tends to be something that is a little more challenging to sort out. It's a conversation to figure out where your patient currently is from a rhythm standpoint, where you're trying to move them to. So not something I would use typically for insomnia, but more if you're trying to adjust somebody's timing.  Dr Grouse: Excellent point and great recommendations. Now, switching gears a little bit, you had mentioned and you alluded earlier that circadian rhythm disruption can be something that we find in certain neurologic diseases and conditions we all treat and may even be an early sign of some of them. What are some general conditions in neurology that we see circadian rhythm disruption? Dr Abbott: So, I think one of the areas where it's often an early sign of a disorder is in neurodegenerative disorders. So, we often do see that that typical daily rhythm and amplitude, and what I mean by that is that sort of difference between how active you are during the daytime and how inactive you are at night. That tends to become dampened and more fragmented even before you start to see some of the other signs and symptoms of neurodegenerative disorders, so things like Alzheimer's. So, it often can be kind of an early hallmark that something else might be coming. Now, other ways that we can see circadian rhythm disruption in other neurologic disorders, I think probably the more under-recognized is in any disorder where a patient may have decreased mobility, sort of overall inactivity during the day. Maybe they have chronic pain, maybe they have really bad migraines, so they're spending lots of time in a dark room disrupting their sleep schedule. All of these things can lead to patients having more of an irregular pattern, so having chunks of sleep and wake that are just sort of distributed randomly throughout the night and the day, and they lose that overall rhythmicity to their behaviors, which then translates into a loss of rhythm and light exposure, a loss of rhythm in food intake. All of these things can kind of build on each other.  Dr Grouse: Well, that's a really good point. You know, often we think of, you know, sleep disruption causing a lot of these problems, like migraine being a very common one. But don't think about as much of the fact that the migraine itself could be contributing to the sleep dysfunction. So, a very, very interesting point there. Now, I was curious, having read the article, what isn't in the article that you wanted to put in?  Dr Abbott: So, I think the focus of this article really was primarily on the neurologic aspect of things, but I do think it's important that if people are interested in this and excited about this area, that they recognize that it's not just neurologic disorders that are impacted by this. There's a lot of really exciting research going on in the area of oncology, for example. There's some really cool research showing that the timing of your first dose of chemotherapy actually dramatically impacts your outcomes. And so, I think there are a lot of really interesting areas where thinking about your circadian system can really optimize treatment, not just within the area of neurology.  Dr Grouse: That's amazing. Well, I'll be really interested to see where that heads. And then of course, on that same topic, any new treatments or diagnostic modalities on the horizon that our listeners should be on the lookout for?  Dr Abbott: So, I think as a field, we are always looking for better ways of looking at circadian markers within the clinic. And so, multiple groups, including our own, have been looking at blood tests. So, is there a way that with one or two samples we can actually get a profile of what your current biological time is? And so, I think those blood tests are still being validated in patients with disorders. We've mostly looked at them in healthy controls. I think other areas we're looking at new diagnostic tools to actually get a sense of how people are responding to their environment. So, we're doing a study looking at using pupillometry, which is a way of measuring how your pupil responds to light, and using that to figure out whether you may or may not be somebody who responds well to light or poorly to light, and can we tailor your treatments for that? So, I think we're looking at many different ways that we can improve diagnostics in the outpatient setting.  Dr Grouse: Well, that's really fascinating. I can't wait to hear more about what may be coming around the corner. Thanks so much for sharing, and I'm sure you've inspired some of our trainees considering a career in sleep medicine. Thank you so much for sharing, and I really again encourage all of our listeners to check out her wonderful article.  Dr Abbott: Thanks for having me. It was great to have a chance to talk about this, and I second your hope that more trainees will be interested in sleep and circadian medicine. It's really an exciting field to get into.  Dr Grouse: Again, today I've been interviewing Dr. Sabra Abbott about her article on circadian neurology. This article appears in the August twenty twenty-six Continuum issue on Neurology of Sleep. Be sure to check out Continuum Audio episodes from this and other issues, and thank you to our listeners for joining today.  Dr Monteith: This is Dr. Teshamae Monteith, associate editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audiocme. Thank you for listening to Continuum Audio. 

Dr. Nicole Rivera and Dr. Nick Carruthers break down why so many people jolt awake between 2 and 3am with worry, fear or full-blown panic — the melatonin-to-cortisol handoff, the brain's overnight detox pathway, and the subconscious material showing up in your dreams. What this episode is about Waking at 2 or 3 in the morning with worry, fear or panic is one of the most common things we hear after fifteen years of practice. Most people reach for the obvious explanations — too much wine, too much caffeine, ate too late. In this episode Dr. Nicole Rivera and Dr. Nick Carruthers walk through the two layers they actually look at. Layer one — the biochemical story Melatonin does more than make you sleepy. It is also part of how the brain clears what it accumulated during the day. Where the load comes from: heavy metals, dental materials, mouth and sinus products, everyday chemical exposure, and what travels up from the gut. When melatonin gets used up early, cortisol — the hormone that wakes you — arrives hours ahead of schedule. Instead of rising at 5 or 6am, it rises at 2 or 3am, and you wake with a racing mind. Why reaching for a melatonin supplement is a band-aid: it can speed the process up without any of the drainage pathways being open first. Kidneys, liver, lymphatics, neck and sinuses come first. Layer two — the subconscious story The emotion you wake up in is information. What were you dreaming about? Perceived imbalance — the moments we labelled purely good or purely bad — keeps running at night. Balancing the perception is what settles it. Clarity builds confidence, confidence allows action. Write the fragment down in the morning, even one image, and decode it in the INNSPO app. Mentioned in this episode Prior episode: "Your Brain Can't Poop" — the deeper dive on brain detoxification INNSPO dream decode and daily practice Your Integrative Life Compass — 13 questions, about 4 minutes, no email required Next step If you wake up at 3am and nobody has been able to tell you why, start with Your Integrative Life Compass at integrativeyou.health/compass. It points you at the pattern rather than another supplement. See Healthcare Differently. Links from this episode Full episode page, transcript and resources Watch this episode on YouTube DNA Precision Free: Your Integrative Life Compass — 13 questions, 4 minutes Go deeper with the DNA Precision Program — epigenetic hair analysis, heavy metal mapping, and lab-validated protocols. waking up at 3am · 3am anxiety · waking up with panic at night · melatonin brain detox · glymphatic system · cortisol spike early morning · circadian rhythm · middle of the night anxiety · dream analysis · root cause insomnia · functional medicine sleep · Integrative You Radio Integrative You — helping self-led families build lives they do not need to recover from. integrativeyou.health

Melatonin may help some children fall asleep, but Dr. Terry Nguyen says it shouldn't be the first solution for sleep struggles. In this episode, she explains when melatonin may have a role, why sleep routines should come first, and what parents should know before giving their child an over-the-counter supplement.

Magnesium gummies, sleepy girl mocktails, melatonin supplements—there are plenty of products promising a better night's sleep. But do they actually work? In this episode, we're breaking down magnesium and melatonin, what the research says, and whether deserves a spot in your nighttime routine.3 things you'll learn:How magnesium and melatonin work differently in the bodyWhat the research actually says about their effectiveness for sleepWhen a supplement may be helpful—and what to consider before taking one

We talk about aging like it happens to a whole person at once. It doesn't. It happens organ by organ, at different speeds, and most people never find out which part of them is running ahead until something breaks.Dr. Will Cole has spent sixteen years running one of the first functional medicine telehealth centers in the world, and he came to this conversation with a case that is both clinical and personal. In 2023 his father lost consciousness at the wheel and died in the crash. The autopsy pointed to cardiometabolic changes, and his heart cells had been aging faster than the rest of him. That same year, Stanford researchers found that one in five adults over fifty has at least one organ aging faster than the others, and that when it's the heart, the risk of a cardiac event more than triples.His new book with Dr. Josh Axe, Heal Your Cells, makes an argument that reframes most of what gets called normal aging. Exhaustion, brain fog, the weight that will not move, the hormone shifts nobody can explain. These are not the calendar. They are cells that have stopped reading their own instructions clearly, and that is a state you can change.We get into what actually makes a cell feel unsafe, why your gut lining is one cell thick and therefore the first thing to break, and the point almost nobody makes about elimination diets: the reintroduction matters as much as the elimination, and a protocol you never came off of is a cast you left on until the muscle atrophied.We also get into light. Not just morning sun, but the darkness half, which matters more for women than most people realize. Melatonin is not only a sleep hormone, it's one of the more important antioxidants for ovarian aging, and light levels most people would call almost nothing can cut its production substantially.Track your sleep, recovery, strain, and HRV with WHOOP. Get one month free at https://join.whoop.com/kaylabarnesOptimize your sleep with the Eight Sleep Pod. Get up to $350 off at https://www.eightsleep.com/Kayla with code “KAYLA”Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women's health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you'll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.https://kayla-barnes-lentz.circle.so/female-longevity-communityConnect with Kayla:Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter:https://x.com/femalelongevityWebsite:https://www.kaylabarnes.com/Spotify:https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054Apple:https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227Follow Her Female Protocol: https://www.protocol.kaylabarnes.comConnect with Dr. Will:Website: http://drwillcole.com/Book: https://drwillcole.com/books-home-page/Instagram: https://www.instagram.com/drwillcoleLinkedIn: https://www.linkedin.com/in/drwillcole/YouTube: https://www.youtube.com/user/DrWillCole#cellularhealth #longevity #femalelongevity #guthealth #healthspan #leakygut#womenshealth #functionalmedicine #circadianhealth #autophagy #mitochondria #healthoptimization

Every two weeks, your hosts MP and Ben present ten new songs from indie and unsigned artists. On this episode: MP caves, Ben raves, and the boys discuss how some bands are making art a natural extension of their music. Also, MP takes the word "barnyardian" for a test drive.EPISODE PLAYLIST:Neighbour Club, "Gold Leaf Girl"Cardinal Bloom, "Melatonin"million bijillion, "Michael"Paper Lady, "Cellsword"Sour Widows, "Lucky Star"French Film, "Let Go of Precious Things"I See Orange, "Allow Me"Jerry Big's World Famous Band, "Berlin"The Joy Hotel, "May Queen"SKORTS, "Headrush"lozenge, "communion wine"Bus Crush, "Best Part"BONUS TRACK: French Film, "Crude Charm"Cities added to the map this episode: SwindonMain Theme Song: Faux Fiction, "Hello"Closing Theme Song: manners, please, "Stay Strange"

Your fatigue never lifted. Your brain fog never cleared. You had COVID, you technically recovered, and you have not been the same person since. Dr. Robin Rose is double board certified in internal medicine and gastroenterology. After she left conventional practice she started running much deeper bloodwork on everybody, and the same things kept showing up. White counts in the twos and threes. Ferritin that didn't line up with the iron. Elevated D dimer in people who had no clot anywhere. That last one is what sent her looking. A D dimer is what the ER runs when they think you have a blood clot, so seeing it high in people without one didn't add up. It led her to microclots. Too small to see on a scan, big enough to choke off the circulation where your cells actually pick up oxygen. We get into why she now asks every patient with POTS or mast cell activation when they last had COVID. Why the gut is where a lot of this starts and nobody checks it and why even a mild case isn't nothing, and why so many people feel like they aged five years in one. If you had COVID and never fully bounced back, this conversation is going to explain a lot. The fatigue, the brain fog, the racing heart when you stand up, and the labs that keep coming back normal. Want more practical health tips? Join my newsletter! https://freechapter.lpages.co/newsletter-opt-in/ "Fine" isn't the same as well. Stop waiting to collapse before someone listens. Build your case https://freechapter.lpages.co/how-to-build-a-case-for-yourself/ Check us out on social media: https://www.instagram.com/drefratlamandre https://www.facebook.com/drefratlamandre https://www.tiktok.com/@drefratlamandre #functionalmedicine #drefratlamandre #medicaldisruptor #NPwithaPHD #nursepractitioner #medicalgaslighting Chapters 0:00 - Introduction 2:38 - From Conventional GI to Cellular Medicine 16:53 - The Strange Lab Patterns No One Was Talking About 21:19 - Spike Protein, Vaccines, and Her Own Reaction 28:17 - Prophylaxis and Treatment: Nasal Sprays, Melatonin, Ivermectin 36:16 - Rapid Fire: Dysautonomia, POTS, and Why There's Hope Guest Links: FB: https://www.facebook.com/drrobinrose IG: https://www.instagram.com/dr.robinrose/ Website:https://terrainhealth.org Learn more about your ad choices. Visit megaphone.fm/adchoices

When the mind refuses to stop and the body refuses to rest, something has to give. Andrew Green's Deep Sleep Hypnosis • Relaxing Music • Anxiety Relief, Melatonin Release • Stop Overthinking was created for exactly that standoff... the one happening right now between your exhaustion and your anxiety, between how badly you need sleep and how relentlessly your thoughts keep pulling you back to the surface.This is restoration sleep hypnosis designed for the overthinker... the person whose brain treats bedtime like a second shift. Andrew's guidance moves through the overthinking patterns that keep you awake and replaces them, layer by layer, with something softer and far more useful... the felt sense that tonight, everything is going to be okay.

Bridging The Gap Between "Trying To Sleep" And "Actually SleepingBridging The Gap Between "Trying To Sleep" And "Actually Sleeping Host: "We're talking about the science of sleep today. Most people think of sleep as 'down time,' but--you argue-- it's actually a high-performance 'reset.' What's really happening under the hood when we hit that 7 to 8-hour mark?" Guest: Important Medical Disclaimer: Please understand that I am not a doctor. I have absolutely no medical training. The protocols listed below are based entirely on my personal experience and my own independent study of longevity practices. These methods have worked wonders for me, every person is different. You must do your own due diligence and consult with your physician before attempting to use any of these protocols to ensure they are safe for your specific medical history. Guest: Getting 7 to 8 hours of high-quality sleep each night is the ultimate biological reset for your body. During these hours... The brain: Flushes out toxins

Raw Garlic "Ultimate Biohack" Trend Faces Scientific Scrutiny Raw garlic has gone viral as a morning ritual, with fans crushing a clove, mixing it with honey, and crediting it with everything from lower cholesterol and better insulin sensitivity to cleared acne, eliminated brain fog, and colds cured within 24 hours. The biochemistry behind the trend is real: garlic contains no allicin until it's crushed or chopped, which mixes an enzyme with a sulfur compound to form the active compound, and letting it sit for ten to fifteen minutes before cooking preserves more of that activity. Host Dave Asprey separates what the human data actually supports, modest blood pressure and cholesterol effects, real antimicrobial properties, and a genuine bleeding-risk caution for anyone on blood thinners, from the unproven parasite-cleanse and brain fog claims driving the trend online, drawing on his own EEG tracking to challenge the cognitive benefit narrative directly. Sources: https://nypost.com/2026/09/01/health/is-garlic-the-ultimate-biohack/ https://holisticheartcenters.com/new-cholesterol-guidelines-2026/ ~~ HEPA Air Filtration Linked To Measurable Brain Function Improvements In One Month A new study found that older adults using true HEPA filtration to reduce indoor fine particulate matter saw small but measurable cognitive improvements after just one month, adding to a growing body of evidence connecting air pollution exposure to neuroinflammation and long-term cognitive decline. Host Dave Asprey breaks down why clean air belongs in the biohacking conversation alongside supplements and training protocols, and why the World Health Organization's decision to list air pollution as a modifiable dementia risk factor is a bigger deal than it sounds. Sources: https://www.sciencedaily.com/releases/2026/08/260830000016.htm https://health.yahoo.com/conditions/neurological/dementia/articles/7-dementia-risk-factors-revealed-110006268.html ~~ Egg Yolk-Derived Peptides Show Neuroprotective Effects Against Oxidative Stress New research on phosphopeptides isolated from egg yolk phosvitin found that the compounds reduced reactive oxygen species, improved antioxidant defense markers, and increased neuron survival in cells exposed to oxidative stress in the lab. Host Dave Asprey connects this early but promising finding to his long-standing case for the whole egg, yolk included, as one of the most nutrient-dense foods available, and flags what would need to happen next for this to translate into a usable protocol. Source: https://www.news-medical.net/news/20260827/Egg-yolk-peptides-protect-brain-cells-from-oxidative-stress.aspx ~~ Heat Stroke Survivors Face Elevated Cardiovascular Risk Years Later, Research Shows A closer look at heat stroke recovery reveals it's rarely a one-day event. Survivors of classic heat stroke had three and a half times the rate of ischemic heart disease twelve years later compared to matched controls, along with elevated long-term risk of kidney disease and lingering heat intolerance, fatigue, and dizziness. Host Dave Asprey draws the line between the controlled heat stress he uses deliberately in sauna and hyperthermic conditioning and the uncontrolled, uncooled heat exposure that leaves this kind of lasting cardiovascular damage, and what that distinction means for how to think about any stressor. Source: https://www.latimes.com/science/story/2026-09-01/even-people-who-appear-to-recover-from-heatstroke-may-face-health-issues-later ~~ Long-Term Melatonin Use Linked To Nearly Double Heart Failure Risk In Large Cohort Study A cohort study of over 130,000 adults with chronic insomnia found that those who used melatonin for a year or more had nearly double the rate of heart failure and all-cause mortality compared to non-users, along with a three and a half times higher rate of heart failure hospitalization. Host Dave Asprey walks through why this is observational data, not proof of causation, and why he's stayed a low-dose, occasional melatonin user for years rather than a nightly one, plus what the real underlying driver of chronic insomnia might be for listeners still relying on it every night. Source: https://www.sciencedaily.com/releases/2026/08/260829035228.htm ~~ This episode is designed for biohackers, longevity enthusiasts, and high-performance listeners who want the latest research on nutrition, air quality, brain health, heat stress, and sleep translated into what actually matters for your biology right now. Host Dave Asprey connects viral trends, clinical data, and decades of context into practical frameworks for taking control of your own health decisions. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: raw garlic biohack, allicin formation, garlic blood pressure, aged garlic extract, garlic cholesterol, HEPA air purifier brain health, PM2.5 cognitive decline, air pollution dementia risk, egg yolk phosvitin peptides, oxidative stress neuroprotection, egg yolk nutrition, heat stroke cardiovascular risk, heat stroke recovery, hyperthermic conditioning, sauna protocol, melatonin heart failure risk, chronic insomnia, sleep hygiene, circadian rhythm, biohacking news 2026 Thank you to our sponsors! Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.comKenetik | Instead of pushing your system harder, Kenetik feeds your brain the ketones it craves to fuel calm clarity and steady focus. Go to drinkkenetik.com/DAVE and use code DAVE for a discount.iRestore | Unlock your best hair & skin with @iRestorelaser and HUGE savings on iRESTORE with code DAVE at irestore.com/DAVEResources: • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Intro 00:19 – Garlic & Brain Fog 02:06 – HEPA Filtration & Cognition 03:20 – Egg Yolk Peptides04:16 – Heat Stroke05:22 – Melatonin06:54 - WrapupSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

For years, melatonin has been the go-to fix for a bad night's sleep. But new research is raising real questions about what it might be doing to your heart. In this episode of Healthy Looks Great on You, Dr. Vickie takes you to mini medical school to explain what melatonin actually does in your body, why most supplements contain far more than your body naturally makes (and why the label might not even be accurate), and the timing mistake almost everyone makes when taking it. Then she unpacks new research linking long-term melatonin use to a higher risk of heart failure - what it means, what it doesn't prove, and why sleep itself matters more for your heart than any supplement on the shelf. Because healthy looks great on you. Get Dr. Vickie's free guide, "3 Simple Strategies to Sleep Smarter" (plus a sleep-friendly recipe): healthylooksgreatonyou.com/sleep This content is for informational and educational purposes only and is not a substitute for medical advice.

Five minutes. That is all Andrew Green is asking of you tonight. Fall Asleep In Less Than 5 Minutes Sleep Hypnosis • Anxiety Relief, Melatonin Release • Stop Overthinking is not a promise made lightly... it is a session engineered with precision, built around the understanding that your mind and body are far more ready for sleep than the anxiety and overthinking have been allowing.Through targeted sleep-induction hypnosis, Andrew moves quickly and intentionally... bypassing the mental chatter, interrupting the anxious loops, and guiding your nervous system into the natural release of melatonin your body has been waiting to trigger all evening. There is no lengthy buildup here. No slow burn. Just an immediate, purposeful descent into the kind of rest that restoration sleep hypnosis was always meant to deliver.

(00:00) ANDREW CALLAHAN, sports columnist for the Boston Herald, joins Toucher & Hardy for his weekly hour-long segment in-studio.(14:16.60) Keion White says he's gonna try and take as much melatonin as he can before the flight and when he lands he's gonna go to his room and sleep more. Callahan defends Keion saying that he literally sleeps in the facilities whenever he can.(27:15.85) last pre season 2 stats and a lie episode also broke down the rules of the game Callahan allows a phone a friend card.Please Note: Timecodes may shift by a few minutes due to inserted ads. Because of copyright restrictions, portions—or entire segments—may not be included in the podcast.CONNECT WITH TOUCHER & HARDY: linktr.ee/ToucherandHardyFor the latest updates, visit the show page on 985thesportshub.com. Follow 98.5 The Sports Hub on Twitter, Facebook and Instagram. Watch the show every morning on YouTube, and subscribe to stay up-to-date with all the best moments from Boston's home for sports!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The guys take a few calls, one on Odell Beckham Jr., a man had an issue with “penis flies” at work, and Larry in Indiana calls in and might be vying for a producer job at WFAN. 49ers Defensive End Keion White is looking to “OD on Melatonin” on his flight to Melbourne to prepare for next Thursday's game. Plus, the ideal activities for a boys weekend.

CIA-Chef in Moskau, Klimadürre, Autokrise, AfD will an die Macht - überall Endspiele. Wie lange hält sich Milliardenminister Pistorius auf Platz eins? Was ist GTA 6, mein Sohn? Herzlich willkommen zur Wochenschau mit Millenial Paul und Boomer Hajo Schumacher und diesen Themen: Der Kanzler und die Kinderärztin: Wenn der raue socialmedia-Ton im richtigen Leben ankommt. Sauerkraut gegen Glyphosat. Seltsamer Hashtag: Was verbirgt sich hinter "Time to Divide Germany"? Berlin-Wahlkampf: zwischen Pollerisierung und Kubicki-Plakaten. Heute schon einen Autoschrauber umarmt? Katastrophale Flutwelle: Erinnerungen an Tibet. Facebook und 17 Milliarden Trinkgeld. Schwanz mit Plastiktüte. Was ist ein Pudu? Kaffee, Melatonin, blaues Licht: der Schlaf und die Mythen. Warum schwimmt ganz Paris in der Seine, aber kein Berliner in der Spree? Plus: Gute Reise, liebe Birgit. Folge 70.Shownotes:Leider ausverkauft: Der Dia-Abend mit Chile- und Überwinter-Tipps am 2.9. im PoshTeckelDie MutMacher auf steady unterstützenHier den kostenlosen MutMach-Newsletter abonnierenPodcast Elefantenrunde mit Frank Stauss und HajoHier gehts direkt zu Suses Workshops Der MutMachPodCast auf InstagramPauls Band Udo Butter und das Team mit allen AuftrittsterminenBücher:Suse SchumacherDie Psychologie des Waldes, Kailash Verlag, 2024Michael Meisheit + Hajo SchumacherLaufende Ermittlungen - großartige Krimi-Reihe mit dem Berliner Kommissar Peer Pedes.Band 1, 2 und 3 erscheinen bei Droemer Knaur.Kostenlose Meditationen für mehr Freundlichkeit (Metta) und Gelassenheit (Reise zum guten Ort) unter suseschumacher.deWir bedanken uns bei Markus C. Hurek für das tolle Coverfoto. Hosted on Acast. See acast.com/privacy for more information.

Earplugs, blindfolds, or milk before bed time-if these can't help you get a good night's rest, you might turn to for help. But is this really the best way to solve your sleeping issues? That said, you might want to understand the mechanism behind melatonin before jumping into any impulsive decisions. Tune into this week's Five Minutes Friday to discover the secrets behind melatonin on the market!

In this episode, my guest is Dr. Roger Seheult, MD, is a physician quadruple board-certified in internal medicine, pulmonary disease, critical care medicine, and sleep medicine, an Associate Clinical Professor at the University of California, Riverside School of Medicine, an Assistant Clinical Professor at Loma Linda University, and the co-founder of MedCram. Today, he explains why vitamin D levels strongly predicted COVID-19 outcomes while vitamin D supplementation largely failed to reproduce the benefit, and makes the case that vitamin D is a marker for sunlight exposure rather than the primary mechanism behind it. He describes the near-infrared portion of sunlight which penetrates through the human body, and the hypothesis that it stimulates melatonin produced inside mitochondria, where it acts as a local antioxidant. We discuss randomized trials of infrared light in hospitalized and ICU patients, why greenery reflects infrared while concrete absorbs it, the Green Heart Louisville tree-planting trial, evidence that bright light at night predicts higher mortality, the NEWSTART framework, the Adventist Health Study, and published research on faith, forgiveness, and health. FULL SHOW NOTES: https://docs.google.com/document/d/1uJxnUa3ifCtHbE11v3iQwgTD1-nQD90-PttuS5NN640/edit?usp=sharing Sponsor: Solius https://shop.solius.com/JONATHANJ Code: JONATHANJ   About this guest:Med Cram: https://www.medcram.com/YouTube: https://www.youtube.com/channel/UCG-iSMVtWbbwDDXgXXypARQ X: https://x.com/rogerseheult?lang=en Academic Profile: https://llu.edu/academics/faculty/seheult-roger/education Subscribe to the Newsletter: https://jonathanjarecki.substack.com/Timestamps 00:00 Intro02:29 Dr. Roger Seheult02:59 Dr. Seheult's Love for Science and Medicine10:41 Pillars of Health, "NEWSTART"13:11 Sunlight, COVID, Vitamin-D Paradox, Dr. Seheult's Clinical Experience17:08 Extra-pineal Melatonin, Antioxidant, COVID, ACE2 Receptor, Red Light18:50 Bringing Patients Outside in Sunlight20:05 Sponsor: Solius25:14 Melatonin, Infrared Light27:13 Heliotherapy, Sunlight in Modern Hospitals,  Dr. Rollier, John Harvey Kellogg33:18 Mitochondria, Long-Wavelength Light, Metabolism, Light Penetration Depth36:03 Greenery, Infrared Light Bath, Longevity, New Data, MiEye42:29 Audience Questions42:41 Sunlight on Psychological Health43:47 Artificial Light at Night, Longevity, Mortality47:32 Cloud Coverage, Light Exposure49:40 New Paper Being Published with Dr. Seheult, Dr. Jeffery, Dr. Fosbury, & Zimmerman 50:37 Nutrition53:28 Adventist Health Study, Plant-Based Nutrition, Mechanisms of Action, High Protein01:01:15 Trust: The Science-Backed Health Benefits of Faith01:19:28 Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Social Media, Substack Newsletter

Understanding the impact of late-night eating on blood glucose levels and metabolic health. Exploring the interplay of circadian biology, pancreatic endocrinology, and the role of melatonin in regulating insulin production. Examining the effects of late-night protein-rich meals on glucose levels and insulin response.TakeawaysLate-night eating can lead to high fasting glucose levels due to the interplay of circadian biology and pancreatic endocrinology.Protein-rich meals at night can trigger a metabolic traffic jam, impacting glucose clearance and insulin response.Chapters00:00 The Impact of Late-Night Eating01:40 The Role of Melatonin in Insulin Regulation03:04 Effects of Late-Night Protein-Rich Meals07:35 The Dawn Phenomena and Cortisol10:57 Circadian Metabolic Health Testing

Disclaimer: this podcast & article is educational, not medical advice. Talk to your doctor before changing your diet, exercise routine, or any treatment plan, especially if you're pregnant, nursing, or managing a chronic condition. The Thrive 120 Show reflects my clinical perspective — it isn't a substitute for individualized care.TLDR“Eat less, exercise more” assumes your metabolism is fundamentally intact — that it's a math problem. It's not. It's a biology problem, and biology has a hierarchy: upstream causes and downstream symptoms. Most conventional advice treats the symptoms.I organize the four real drivers of metabolic breakdown into a framework I call MESS²:* M — Muscle loss. Your metabolic engine. Crash dieting shrinks it further.* E — Endocrine disruption. Your control panel — insulin, thyroid, cortisol.* S — Sun exposure. The free, daily signal almost everyone is missing.* S² — Sleep, Stress, and Systemic inflammation. The silent wreckers that undo the other three.Diet and exercise aren't wrong — they're just in the wrong position in the sequence. Fix the foundation first, and they finally start working the way they're supposed to.If you want help figuring out where your own weak link is, check the show notes below for the Thrive 120 programs and the Metabolic Blueprint Session Your metabolism isn't a math problemYou go in for a visit. Labs show your weight creeping up, your blood sugar drifting higher, your energy in the tank. And you hear the familiar line: eat less, cut calories, exercise more.That advice isn't malicious — it comes from a good place. But it assumes your metabolism is fundamentally intact. That it's calories in, calories out, done.Here's the problem: what if the engine itself is damaged? What if the control panel is sending the wrong signals? Adding intense exercise on top of a body that's already inflamed and hormonally dysregulated isn't a fix — it's closer to pouring gasoline on a fire.Think about it the way you'd think about a car. If the engine light comes on and the car starts making a bad noise, you don't respond by pouring in more premium gas. You find out what's wrong with the engine first. Your body deserves the same order of operations.Left alone, your body doesn't just sit still — muscle drifts downward, hormonal signaling drifts off-schedule, inflammation creeps upward. None of that is a willpower problem. It's biology, and biology has an upstream and a downstream. Most people — and most conventional approaches — spend their time treating the downstream symptoms. Below is the upstream map.THRIVE 120 Substack with TriplePlayDoc is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.The MESS² FrameworkM — Muscle: your metabolic engineMuscle is metabolically expensive. Your body burns calories just to maintain it, even while you're sitting on the couch doing nothing. The more muscle you carry, the higher your resting metabolic rate; the less you carry, the fewer calories your body needs — and the easier it becomes to store fat.After about age 30, you naturally lose muscle mass every decade — commonly cited figures put it in the 3–8% per decade range, accelerating further after roughly age 60 to 70.¹ ² ³ This gradual process is called sarcopenia, and because it happens slowly, most people don't notice until it's already reshaped their metabolic baseline.Here's where it gets worse: when most people try to “fix” their metabolism, they reach for a calorie-restricted diet. Yes, the scale moves. But a meaningful portion of that loss isn't fat — it's muscle. You've made the engine smaller and lowered your metabolic floor. Then you return to normal eating (because restriction isn't sustainable long-term), and your body — now running a smaller engine — needs fewer calories than it did before. The result is the yo-yo cycle, and each round tends to leave you carrying a little more than the last time.If that pattern sounds familiar, it's not a willpower problem. It's a muscle problem, and muscle problems have muscle solutions: protecting and building lean tissue before you fixate on how much you're eating.E — Endocrine disruption: your control panelIf muscle is the engine, your hormones are the control panel. When the control panel sends the wrong signals, it doesn't matter how good the engine is underneath — nothing runs right. Three hormones do most of the damage:Insulin. Insulin's normal job is to move glucose out of your bloodstream and into your cells. When cells are bombarded with insulin repeatedly — from a diet high in refined carbohydrates and sugar, chronic stress, poor sleep, or excess artificial light exposure — they start tuning it out. That's insulin resistance. Blood sugar stays elevated, your body compensates by producing even more insulin, and because insulin is a storage hormone, chronically elevated insulin locks you out of fat-burning mode. Fat oxidation requires insulin to be low — it's not optional.Thyroid. Your thyroid sets the pace for how fast or slow every cell in your body runs. The standard screening test — TSH (thyroid-stimulating hormone) — is just a signal sent from the brain to the thyroid. It doesn't tell you how much active thyroid hormone is actually circulating, whether it's converting properly, or whether something is blocking it at the cellular level. It's common to see patients with textbook hypothyroid symptoms — fatigue, weight gain, brain fog, feeling cold, constipation — while TSH reads “normal.”Cortisol. In short bursts, cortisol is your friend — it gets you moving and helps you respond to real threats. Chronically elevated cortisol is a different story. Your body reads sustained high cortisol as famine or threat, so it holds onto visceral fat (the fat around your organs) as an energy reserve and breaks down muscle tissue to convert into quick glucose. That's a double hit: your engine (muscle) shrinks while your fat stores grow. This is also why jumping straight into intense daily cardio when you're already exhausted and stressed tends to backfire — that kind of training spikes cortisol further, adding fuel to the exact hormone working against you. Exercise is medicine, but which exercise depends heavily on where you're starting from.S — Sun exposure: the signal almost everyone is missingThis is the piece most health-conscious people have never connected to their metabolism — and it goes well beyond “get sunlight for vitamin D.”Alpha-MSH. Ultraviolet light exposure triggers the release of alpha-melanocyte-stimulating hormone (alpha-MSH), produced via the pituitary–hypothalamic axis. Most people only know it as the hormone behind tanning, but alpha-MSH also acts directly on the hypothalamus — the brain region that governs hunger, body temperature, and energy expenditure. Through the melanocortin receptor system (MC3R/MC4R), alpha-MSH suppresses appetite and raises energy expenditure.⁴ ⁵ This is well-established endocrinology at the receptor level; most of the direct evidence for the light-triggered release piece specifically comes from animal and combined animal/human research, so treat “morning sunlight measurably curbs your appetite today” as a reasonable, biologically grounded hypothesis rather than a proven guarantee for every individual.Melanin. Most people think of melanin purely as sun protection. There's also a genuinely interesting — and genuinely early-stage — line of research suggesting melanin can absorb light energy and convert it into other forms of biological signaling.⁶ I want to be direct about where this stands: the clearest demonstrations of melanin's light-to-chemical-energy conversion come from turtle, avian, and in-vitro photoelectrochemical studies, not controlled human metabolic trials.⁷ It's a fascinating emerging area, not an established mechanism for human fat loss — I'm flagging it as something to watch, not something to build a protocol around yet.Melatonin. Most people file melatonin under “sleep supplement.” Its more fundamental role may be different: melatonin is one of the most potent antioxidants in the body, and a substantial body of research — much of it from melatonin researcher Russel Reiter's lab — supports it functioning as a mitochondria-targeted antioxidant that protects your cellular energy factories from oxidative damage.⁸ Melatonin production is directly regulated by light: it rises in darkness and is suppressed by light exposure, which ties it tightly to your circadian rhythm. When melatonin is disrupted — by artificial light at night, poor sleep, or insufficient daytime sunlight — your mitochondria lose one of their primary protectors, and cellular energy production can suffer as a result.Your morning light exposure sets your circadian clock, and that clock governs when cortisol should peak (morning) and fall (night), along with downstream thyroid output and insulin sensitivity. When the clock drifts, those downstream systems drift with it.S² — Sleep, Stress, and Systemic inflammation: the silent wreckersThese three are grouped together because they feed each other, forming what I'd call a metabolic wreckage loop.Sleep. One frequently cited controlled study found that cutting sleep from 8.5 to 5.5 hours a night — while holding calorie restriction constant — reduced the proportion of weight lost as fat by 55% and increased the loss of lean (muscle) mass by 60%.⁹ It's worth noting this came from a small trial (10 participants), though a separate free-living study found a similar shift in body composition over eight weeks.¹⁰ Sleep is also when your body releases growth hormone, the primary fat-burning, muscle-repairing hormone — cutting sleep short cuts those pulses short too. As for hunger hormones: classic research found sleep restriction lowers leptin (the “you're full” signal) and raises ghrelin (the “you're hungry” signal),¹¹ though it's fair to flag that more recent meta-analyses have found this effect isn't consistent across every study,¹² so treat it as a plausible contributor rather than a guarantee for any one person.Stress and inflammation. Chronic stress increases intestinal permeability — commonly called “leaky gut.” When the gut lining becomes more permeable, bacterial fragments and inflammatory particles can enter the bloodstream, and the immune system responds the way it would to an infection: with inflammatory cytokines. Those cytokines can interfere with insulin receptor signaling, contributing to insulin resistance that has nothing to do with what you ate that day.¹³ ¹⁴ Some early gut-microbiome research adds another wrinkle: in animal studies, mice with an “obese-type” microbiome extracted measurably more energy from identical food than mice with a “lean-type” microbiome, and this trait was transmissible via microbiota transplant.¹⁵ Human data shows a correlated shift in gut bacterial composition with obesity and weight loss, but the calorie-harvesting mechanism itself has been demonstrated most directly in mice — worth remembering before assuming it applies identically in people.So when do diet and exercise actually work?Diet and exercise are genuinely powerful tools — they're just not the starting point. They're amplifiers. If what's underneath is hormonal chaos, mitochondrial strain, and chronic inflammation, adding intense exercise and severe caloric restriction just amplifies that chaos. But once the foundation is addressed — light exposure is consistent, sleep is protected, inflammation is trending down, hormones are moving in the right direction — diet and exercise become the rocket fuel. It's the same idea as tuning a guitar before you play it: you wouldn't walk on stage with an out-of-tune instrument and just strum harder.The sequence: light and circadian rhythm first, then sleep, then inflammation, then hormones, then nutrition, then movement. Work from the foundation up, not the top down.Five things to start this week* Get morning sunlight. Within 30–60 minutes of waking, get outside for 10–20 minutes — no sunglasses, no sunscreen, no contacts if you can manage it. Face the direction of the sun without staring directly at it. This is free, takes 15 minutes, and is one of the most direct levers you have on circadian rhythm.* Protect melatonin at night. After sunset, start dimming household lights. Get off screens, or use blue-light-blocking glasses if you can't.* Ask for the right labs. Beyond a basic metabolic panel and TSH: fasting insulin, a full thyroid panel (free T3, free T4, reverse T3), a cortisol curve, and high-sensitivity CRP. These numbers point to which layer of MESS² to address first.* Remove one inflammatory food this week. Just one — refined seed oils (canola, soybean, vegetable) or ultra-processed snacks are a reasonable place to start.* Pause intense exercise if you're exhausted and inflamed. Counterintuitive, but if your body is in survival mode, a 20–30 minute walk lowers cortisol, improves insulin sensitivity, and moves your lymphatics better than another hard session would. Save high intensity for once the foundation is in place.The bottom lineYour metabolism isn't broken — it's very likely just misunderstood, and it's responding logically to signals it's been given: too little muscle to defend, a control panel sending mixed messages, a missing daily light signal, and a background hum of stress and inflammation. None of that is a character flaw. It's biology, and biology responds to sequence.Find your weak link in the framework above. Start at the foundation, and build from there — not the other way around.If this resonated and you want a structured way to work through the MESS² framework for your own situation, the Thrive 120 programs walk through it step by step, and a Metabolic Blueprint Session is a good next move if you want a second set of eyes on your specific labs and history. (Use THRIVER20 at checkout to get 20% off for the life of your membership)References* Preserve your muscle mass — Harvard Health: https://www.health.harvard.edu/staying-healthy/preserve-your-muscle-mass* Sarcopenia (Muscle Loss With Aging) — Cleveland Clinic: https://my.clevelandclinic.org/health/diseases/23167-sarcopenia* An Overview of Sarcopenia: Focusing on Nutritional Treatment Approaches — PMC: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11990658/* Alpha-Melanocyte-Stimulating Hormone-Mediated Appetite Regulation in the CNS — Neuroendocrinology, Karger: https://karger.com/nen/article/113/9/885/836595/Alpha-Melanocyte-Stimulating-Hormone-Mediated* Solar UVB radiation promotes α-MSH secretion via the pituitary–lung axis (human and mouse data) — PMC: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10497598/* Photoelectrochemical properties of melanin — Nature Precedings: https://www.nature.com/articles/npre.2007.1312.1.pdf* The Unsuspected Capacity of Melanin to Transform Light Energy into Chemical Energy (turtle/avian model) — ResearchGate: https://www.researchgate.net/publication/282330655_The_Unsuspected_Capacity_of_Melanin_to_Transform_Light_Energy_into_Chemical_Energy_and_the_Surprising_Anoxia_Tolerance_of_Chrysemys_Picta* Melatonin as a mitochondria-targeted antioxidant: one of evolution's best ideas — Reiter et al., J Pineal Res: https://onlinelibrary.wiley.com/doi/10.1111/jpi.12360* Insufficient Sleep Undermines Dietary Efforts to Reduce Adiposity — Nedeltcheva et al. 2010, Annals of Internal Medicine (PMID 20921542): https://www.acpjournals.org/doi/abs/10.7326/0003-4819-153-7-201010050-00006* Muscle Loss While Dieting Jumped With Less Sleep (summary including Wang et al. 2018 free-living replication) — FitChef: https://fitchef.com/shorts/sleep-keep-muscle-while-dieting/* Sleep Curtailment in Healthy Young Men Is Associated with Decreased Leptin, Elevated Ghrelin — Spiegel et al. 2004, Annals of Internal Medicine: https://www.acpjournals.org/doi/10.7326/0003-4819-141-11-200412070-00008* The Impact of Sleep Deprivation on Hunger-Related Hormones: A Meta-Analysis and Systematic Review — MDPI: https://www.mdpi.com/2673-4168/5/2/48* Gut microbiota, intestinal permeability, and systemic inflammation: a narrative review — PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC10954893/* Cytokines and intestinal epithelial permeability: A systematic review — PubMed: https://pubmed.ncbi.nlm.nih.gov/37030338/* An obesity-associated gut microbiome with increased capacity for energy harvest (mouse model with human comparison) — Turnbaugh et al. 2006, Nature: https://www.nature.com/articles/nature05414 This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit tripleplaydoc.substack.com/subscribe

Send Zorba a message!Good news for coffee lovers! It may slow down the aging process. Zorba also talks about how 4 out of 5 toddler foods are ultra-processed. He answers emails about melatonin, breaks down a listener's cholesterol numbers, and reads some podcast reviews.Support the showProduction, edit, and music by Karl ChristensonSend your question to Dr. Zorba (he loves to help!):Phone: 608-492-9292 (call anytime)Email: askdoctorzorba@gmail.comWeb: www.doctorzorba.orgStay well!

Send Zorba a message!Good news for coffee lovers! It may slow down the aging process. Zorba also talks about how 4 out of 5 toddler foods are ultra-processed. He answers emails about melatonin, breaks down a listener's cholesterol numbers, and reads some podcast reviews.Support the showProduction, edit, and music by Karl ChristensonSend your question to Dr. Zorba (he loves to help!):Phone: 608-492-9292 (call anytime)Email: askdoctorzorba@gmail.comWeb: www.doctorzorba.orgStay well!

Barbara and Jacie discuss insomnia as a common CIRS symptom, explaining that CIRS (Chronic Inflammatory Response Syndrome) can occur in genetically predisposed people exposed to biotoxins like mold, algae blooms, or venomous spider bites, leading to chronic inflammation, cytokine activity, low MSH, and downstream disruption of melatonin, cortisol, and other hormones. They share ways to improve falling asleep (morning sunlight, dim evening lighting, low-dose melatonin, bedtime grounding routines, time-boxing bed use, and acupuncture) and staying asleep (addressing nighttime blood sugar drops with a protein/fat or protein/fiber snack, and managing nocturia from ADH/osmolality dysregulation with electrolytes, fluid timing, and pre-bed bathroom trips). They also cover unrefreshing sleep, sleep environment optimization, hormone testing (including DUTCH panels), and supplements and supports they use, including magnesium, L-theanine, glycine, and KPV, emphasizing practitioner guidance and treating CIRS as the root cause. For more information and support, join us at https://thecirsgroup.com TIMESTAMPS 00:00 Sleep: intro and disclaimer 00:45 What Is CIRS? 02:01 Low MSH and poor sleep connection 03:51 Circadian rhythm resets 05:55 Lighting to support sleep 06:23 Melatonin Done Right 06:46 Anxiety disrupting sleep (cell danger response) 08:37 Benefits of acupuncture 10:09 Why you have trouble staying asleep 11:00 Tips to stabilize your blood sugar 11:53 Nocturia (needing to pee in the middle of the night) 14:00 Unrefreshing Sleep: tips and tricks 15:40 Hormones and Testing 18:33 Personal Sleep Stacks 20:48 Ashwagandha Nightshade PSA 21:31 KPV for Low MSH 22:27 Wrap Up and Next Steps For more information and support, join us at https://thecirsgroup.com HELPFUL LINKS MENTIONED IN THE EPISODE: Our episode on what CIRS is: https://youtu.be/eqso4R0cQhg?si=9klrfHeuyKGfUJ4n Order Jacie's book! The 30 Day Carnivore Bootcamp: https://a.co/d/7MgHrRs The CIRS Group: Support Community: https://thecirsgroup.com Instagram: https://www.instagram.com/thecirsgroup/ Find Jacie for carnivore, lifestyle and limbic resources: Jacie's book on the Carnivore diet!  https://a.co/d/8ZKCqz0 Instagram: https://www.instagram.com/ladycarnivory YouTube: https://www.youtube.com/@LadyCarnivory Blog: https://www.ladycarnivory.com/ Find Barbara for business/finance tips and coaching: Website: https://www.actlikebarbara.com/ Instagram: https://www.instagram.com/actlikebarbara/ YouTube: https://www.youtube.com/@actlikebarbara Jacie is a Shoemaker certified Proficiency Partner, NASM certified nutrition coach, author, and carnivore recipe developer determined to share the life changing information of carnivore and CIRS to anyone who will listen. Barbara is a business and fitness coach, CIRS and ADHD advocate, writer, speaker, and a big fan of health and freedom. Together, they co-founded The CIRS Group, an online support community to help people that are struggling with their CIRS diagnosis and treatment.

Episode Description: You are probably taking melatonin wrong and it is almost certainly not your fault. Most people take it like a sleeping pill every night, wake up groggy, and eventually need more and more to get the same effect. That is not a melatonin deficiency. That is melatonin being used for something it was never designed to do at a dose your body would never produce on its own. The amount of melatonin your brain actually releases at night is about 3 tenths of 1 milligram. Your gummy says 10. The research is humbling and the label may not even be accurate. Researchers tested 30 melatonin products off store shelves and found the real content ranged from 83% below the label to nearly five times above it. In roughly one out of four products they found serotonin, a compound that was not listed on the label at all. In this episode, you will learn: •  Why melatonin is a timing hormone and not a sedative, what it is actually designed to do in the body, and why taking a giant dose expecting to be knocked unconscious was never how it works •  Whether long term melatonin use shuts down your body's own production, why the answer is no, and what the real risks actually are •  Why Dr. G never raises the dose when a patient says melatonin has stopped working, what he does instead, and the specific scenarios where melatonin is genuinely the right tool Plus the warning every parent needs to hear before giving melatonin to a child. Product reviews assess both brand transparency and product quality. If a company doesn't respond to our outreach, it doesn't automatically mean their product is low quality but it does mean they're failing their customers on transparency and communication. We reach out multiple times. No response isn't an oversight, it's a choice. And consumers deserve better. Timestamps:0:00 - Intro 1:30 - The One Thing About Melatonin That Changes Everything 2:30 - Mistake #1: The Dose Most People Take Is 10 to 30 Times Too High 4:00 - Will Melatonin Shut Down Your Body's Own Production? The Real Answer 5:30 - Mistake #2: Using It Like a Sleeping Pill When It Was Never Designed for That 7:00 - Mistake #3: The Study That Shows You Can't Trust the Number on the Label 8:30 - How Dr. G Actually Has His Patients Use Melatonin 9:30 - The Warning Every Parent Needs to Hear Before Giving This to Their Kids 10:00 - The Whole Truth in One Line Get your free guide from Dr. G:  https://page-builder-christiangon110.replit.app/opt-in/ Learn more about your ad choices. Visit megaphone.fm/adchoices

The new vaccine schedule recommendationsMy urologist is giving me grief that my vitamin D level is too highWhich nattokinase do you recommend to treat long covid?Is the vitamin K in your bone protocol different from the heart protocol?What about methylated B vitamins for brain vs. heart health?

Have you ever found yourself staring at a brightly colored gummy bottle in the pharmacy aisle, hoping a quick supplement fix will finally give you a full night of uninterrupted sleep? The promise of an easy solution is incredibly tempting, but what if these trendy sleep hacks are actually masking deeper behavioral shifts your child really needs? In this episode, I connect with pediatrician and sleep medicine specialist Dr. Craig Canapari to separate social media fiction from clinical fact when it comes to pediatric sleep aids. Dr. Canapari breaks down the true neuroscience behind melatonin as a hormone, shines a light on the dramatic rise in accidental supplement overdoses, and uncovers what the data actually says about the viral magnesium foot rub trend. The Rise of the "Purple Aisle": Why exhausted parents and heavy marketing are driving an unprecedented surge in pediatric sleep supplements. Melatonin is a Hormone, Not Candy: The vital distinction between a natural biological trigger and utilizing exogenous melatonin as a hypnotic knockout pill. The Nuance of Dosing: How melatonin can genuinely support neurodiverse children (like those with autism or ADHD) and why timing it right is everything. The Poison Control Warning: The alarming 500% spike in melatonin overdoses and the critical danger of loose food supplement regulation. Diving into the Magnesium Hype: Sorting through the TikTok claims of magnesium sprays and lotions to find out if there is any real pediatric evidence behind them. The True Root of Sleep Issues: Why natural fads often act as a barrier to established, highly effective behavioral sleep hygiene adjustments. The 20-Second Sleep Pitch: Dr. Canapari's foundational pillars—from consistent wake times to the ultimate goal of independent sleep—to safely reclaim your family's rest. Connect with Dr. Craig Canapari on Instagram @drcanapari, visit his site www.drcraigcanapari.com and buy his book It's Never Too Late To Sleep Train: https://amzn.to/45UnnlX  (paid link) Sleep edit podcast: https://drcraigcanapari.com/podcast/episode-12-melatonin-and-magnesium-oh-my/ IPSA position paper on melatonin in typically developing children: https://www.sciencedirect.com/science/article/abs/pii/S1389945725000474 Magnesium: https://drcraigcanapari.com/magnesium-for-kids-sleep/ https://drcraigcanapari.com/magnesium-sprays-and-lotions/ Melatonin: https://drcraigcanapari.com/should-my-child-take-melatonin-a-guide-for-parents/ https://drcraigcanapari.com/melatonin-overdoses 00:00:00 - Introduction to Sleep Supplements 00:00:41 - Meet Dr. Craig Canapari 00:03:10 - Dr. Canapari's Background & Yale Pediatric Sleep Center 00:06:44 - The Rise in Supplement Use 00:10:41 - Melatonin Explained: How It Works & Dosing Risks 00:18:10 - When Melatonin Can Be Beneficial 00:22:00 - Magnesium for Kids: Hype vs. Evidence 00:33:09 - Topical Magnesium Sprays & Safety Concerns 00:43:56 - Foundational Sleep Habits & Independent Sleep 00:47:35 - Closing Thoughts & Where to Find Dr. Canapari Our podcasts are also now on YouTube. If you prefer a video podcast with closed captioning, check us out there and ⁠subscribe to PedsDocTalk⁠. Get trusted pediatric advice, relatable parenting insights, and evidence-based tips delivered straight to your inbox—join thousands of parents who rely on the PDT newsletter to stay informed, supported, and confident. ⁠⁠⁠⁠Join the newsletter⁠⁠⁠⁠! Shop Dr. Mona's favorite products: https://shopmy.us/shop/pedsdoctalk (paid link) And don't forget to follow ⁠⁠⁠⁠@pedsdoctalkpodcast⁠⁠⁠⁠ on Instagram—our new space just for parents looking for real talk and real support. We love the sponsors that make this show possible! You can always find all the special deals and codes for all our current sponsors on the ⁠PedsDocTalk Podcast Sponsorships⁠ page of the website. Learn more about your ad choices. Visit podcastchoices.com/adchoices

How much is sleep actually affecting your HYROX performance?Rich Ryan sits down with with Dr. Rafael Zuzuarregui to break down sleep, recovery, jet lag, melatonin, circadian rhythm, and the strategies athletes can use when traveling for HYROX races. They also dive into sleep wearables, screen time, cooling mattresses, cold plunges, supplements, and which popular sleep hacks are actually worth trying.If you're racing HYROX overseas, preparing for World Championships, or simply trying to recover and perform better, this episode gives you practical ways to make sleep one of your controllables.02:16 – Melatonin, circadian rhythm & jet lag14:43 – How to sleep on flights before a HYROX race20:38 – How poor sleep impacts athletic performance36:53 – The best sleep environment for recovery57:40 – Ranking popular sleep hacks for athleteshttps://www.rmr.training/

Hello Beautiful, I'm so grateful you're here with me. When your mind refuses to slow down, this meditation helps create the calm you've been craving. This 3 hour sleep meditation gently quiets overthinking, relaxes your nervous system, and prepares your body for deep, uninterrupted sleep. Perfect for insomnia, racing thoughts, stress relief, and bedtime relaxation. Love,

In this episode, Dr. David Jockers explores why many people struggle to burn fat despite eating well and exercising. You'll discover how your metabolic environment, circadian rhythm, and meal timing influence fat storage and what changes can help shift your body toward fat burning.   You'll learn why eating late at night can impact insulin sensitivity, liver function, melatonin production, and mitochondrial health. Dr. Jockers breaks down the connection between fasting, sleep, and the body's natural ability to burn fat while you rest.   You'll also discover the seven-day protocol designed to support a healthier metabolism, including strategies for meal timing, hydration, protein intake, and creating the right conditions for your body to burn fat more efficiently. In This Episode:  00:00 Why Youre Not Just Overeating 00:17 Podcast Intro and Support 04:39 Survival Mode and Toxic Fat 07:07 Circadian Rhythm Fat Loss Key 07:50 Daylight Eating Five Steps 12:05 Why Night Eating Backfires 16:58 Melatonin and Growth Hormone 19:24 Seven Day Reset Timeline 20:40 FAQs Meals Shift Work Events 25:55 Wrap Up and Final Thanks   Boost your resilience and combat stress with Purality Health's premium Ashwagandha formula. This powerful adaptogen helps restore balance, improve energy, and reduce anxiety, all while supporting your overall wellness. Purality Health's unique Mycel Liposomal technology ensures maximum absorption for fast and effective results. Don't just take our word for it—try it risk-free for six months and experience the benefits for yourself! Visit http://longevityroot.com/drj to claim your exclusive offer and start feeling your best today.   If you're looking for a simple way to support healthier, younger-looking skin, the Bon Charge Red Light Face Mask is a game changer. Using scientifically backed red and near-infrared light wavelengths, it works at the cellular level to energize mitochondria, support skin elasticity, improve complexion, and soften visible signs of aging—all from the comfort of your home. The flexible, cordless design makes it easy to add to your daily routine with just 10–20 minute sessions. Plus, my listeners can get 15% off with free shipping and a 12-month warranty. Visit boncharge.com and use promo code DRJOCKERS at checkout to claim your exclusive offer today.   "You're not always overweight because you eat too much. Sometimes your metabolic environment is out of balance. ~ Dr. Jockers   Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Visit http://longevityroot.com/drj to claim your exclusive offer Visit boncharge.com and use promo code DRJOCKERS for an exclusive offer. Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

What if the fatigue, poor sleep, and slow healing you've chalked up to "just getting older" actually trace back to one molecule you stopped making enough of at 40? Melatonin isn't just a sleep aid. It's your mitochondria's master antioxidant, and its levels fall off a cliff right when you need it most. In today's episode, Dr. John Lieurance joins me to break down why that drop matters so much for energy, detox, and brain health. He shares the research behind super-physiological melatonin dosing,  why suppositories outperform oral and IV delivery, and how melatonin clears heavy metals from the brain.  We talk about his health crisis, root causes of enlarged prostate, and the peptides he uses for skin and tissue repair. We also dig into mold detox, craniosacral therapy, and heart rate variability as a longevity marker.    "400 times more melatonin is secreted by the lining of your gut, triggering microbiome swarming that stimulates the good bacteria to proliferate and inhibit the bad bacteria." ~  Dr. John Lieurance   In This Episode: - Addressing prostate inflammation at the Advanced Rejuvenation clinic - Mitochondrial stress from endogenous and exogenous toxins - Airways, dura and the glymphatic system - Fascia, acupuncture and frequency medicine  - The Warburg effect and melatonin intersect - How melatonin supports heavy metal detoxification - Melatonin and Heart Rate Variability (HRV) - Health benefits of MitoSkin and GHK-Cu Copper - Mold toxicity and detox strategies Products & Resources Mentioned: Dr. John Lieurance's Book: Melatonin Miracle Molecule: https://a.co/d/04I0Zc2L  MitoZen Supplements: Science-backed supplements for NAD+, sleep, immune support, cellular energy, and detoxification: https://www.mitozen.com/  Fresh-Pressed Olive Oil: Try a full-size $39 bottle for just $1 to cover shipping at https://getfreshwendy.com   Tru Energy Skincare Bio Adaptive Hydration Oil: Try the oil and save up to $197 at trytruenergy.com/wendy5   Organifi Collagen: Save 20% with code MYERSDETOX at https://organifi.com/myersdetox   Heavy Metals Quiz: Check your toxicity score and receive a free video series on how to detox your body. Take the quiz at https://heavymetalsquiz.com    About Dr. John Lieurance: Dr. John A. Lieurance, ND, DC, DABCN, is a Sarasota-based naturopathic physician, chiropractic neurologist, author, and educator with nearly 30 years of experience in functional medicine, regenerative medicine, and neurological care. He is the founder of Advanced Rejuvenation and serves as Scientific Advisor and Chief Formulator for MitoZen Scientific, where he focuses on mitochondrial health, advanced delivery systems, melatonin, NAD+, and methylene blue. Dr. Lieurance is widely known for his work with Functional Cranial Release, regenerative therapies, and his research-driven approach to supporting cellular energy, brain health, and whole-body vitality. You can learn more about his work at https://www.advancedrejuvenation.us/ and buy  his supplement line at https://www.mitozen.com/    Disclaimer The Myers Detox Podcast was created and hosted by Dr. Wendy Myers. This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast, including Wendy Myers and the producers, disclaims responsibility for any possible adverse effects from using the information contained herein. The opinions of guests are their own, and this podcast does not endorse or accept responsibility for statements made by guests. This podcast does not make any representations or warranties about guests' qualifications or credibility. Individuals on this podcast may have a direct or indirect financial interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.

You've probably tried everything to sleep better. Magnesium. Melatonin. Blackout curtains. Maybe even expensive sleep gadgets. But what if the real reason your sleep feels broken has nothing to do with any of those things?In this video, Dave Asprey explains a hidden biological process that controls whether your body stays in stress mode at night… or finally switches into deep recovery mode. He breaks down why so many people wake up exhausted, why cortisol stays elevated while you sleep, and why your body may never fully enter repair mode even if you're technically asleep.You'll learn how one overlooked habit affects your brain, metabolism, recovery, heart rate, and overnight repair systems, plus the surprising research that showed dramatic changes in sleep quality from a single adjustment. Once you understand this mechanism, you'll never look at sleep the same way again.Try Danger Creatine: https://dangercoffee.com/products/danger-creatineTry TrueDark glasses: https://truedark.comTry Danger Coffee: https://dangercoffee.com/discount/davetubeTry Suppgrade Labs: https://shopsuppgradelabs.com/I have spent twenty years and millions of dollars testing every legal focus drug I could get my hands on. In this video, I break down which compounds actually work, which ones are a waste of money, and the exact stack that delivers hours of clean focus without the afternoon crash.The shift is simple: focus isn't a willpower problem. It's an energy production problem inside your brain. Once you fuel it at the cellular level, deep focus stops being a struggle and becomes the default state.Thank you to our sponsors!PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off.Viome | Check it out at viome.com and use code 16DAVE for 16% off. It's time to stop guessing and start knowing your body.iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE00:00 – Trailer00:53 – Sleep Environment Matters03:44 – Red Light Bulbs04:50 – Blackout Curtains05:16 – Light-Blocking Glasses07:16 – Morning Supplement Stack07:41 – Creatine for the Brain11:48 – MCT Oil Fuel13:06 – Cellular Cleanup (Autophagy)15:12 – Magnesium for Sleep16:56 – Full Stack Recap18:26 – Biohacking Is AccessiblConnect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/Dave Asprey's BEYOND Conference: https://beyondconference.com/Dave Asprey's New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15Upgrade Labs: https://upgradelabs.com40 Years of Zen: https://40yearsofzen.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What's the real difference between dreaming and waking consciousness?  Neil deGrasse Tyson and co-hosts Chuck Nice and Gary O'Reilly sit down with sleep expert Matt Walker to answer fan questions about the most mysterious thing humans do every single night: sleeping & dreaming. What's the science behind your sleep paralysis demon?  NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here:  https://startalkmedia.com/show/the-dreaming-brain-with-matt-walker/ Thanks to our Patrons Rhagor, Beans, Eric Grant, DOCTOR FN ASTRONAUT, Richard Thompson, Niclas Larsson, Cathy Hayes, SunshineKat Snyder, Brandon, Matt Caldwell, Tim Davies, M.Victoria Delpiano, Heyo13579, Erin McCullough, Shalon Sorensen, Kaydence Johnson, RJ, Dave, Sindre Skybert, Mr. V, Neon lion Blacklight cozylazy, Mary Mitchell, Trip Ni Selo, S. H., Cloud3X, P.M., Dallas, Dan, Getyoducksinarow, David S, Michael Koenig, Jason A, Reg Anderson, Sean Marien, Adeel Rahman, joe hoffmann, Ronald Merrifield, Jesse Miner, David Pazer, Toshi Jordan, Pat Voss, Nicholas Wiseman, Antoine Portes, Colin, David Crouse, Sander van Liempd, Wendy R., J P, Kenneth Cook, Joey, Fixxxer331, Nathan Hinote, Hara Kannajosyula, Heath Horne, Pixtle, Brett M Garabedian, Ryan Alba, Paul Tindall, Tony Stewart, and Stephanie Moore for supporting us this week. Subscribe to SiriusXM Podcasts+ to listen to new episodes of StarTalk Radio ad-free and a whole week early.Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Near-Infrared Light Therapy & EMF Shielding with SaunaSpace Founder Brian Richards Your mitochondria are starving for a nutrient you've probably never tracked, and it's not a vitamin or a macro. This episode reveals how a forgotten 1910 therapy uses light to physically restructure water inside your cells, unlocking a mechanism for healing, detox, and mitochondria repair that most of biohacking has completely overlooked. Go to https://sauna.space/ and use code ‘Dave' for a 15% discount! Host Dave Asprey sits down with Brian Richards, founder of SaunaSpace and a leading voice in incandescent light therapy and infrared sauna engineering. With a background in chemistry and organic synthesis, Brian spent over a decade building a science-backed alternative to LED-based light therapy rooted in full-spectrum incandescent light and deep radiant heat. After healing his own insomnia, adrenal fatigue, and brain fog through light and heat exposure, he developed the FireLight Spectrum, a technology engineered to restore what modern lighting strips away. Dave and Brian trace incandescent light therapy back to Dr. John Harvey Kellogg's 1910 book on light therapeutics, and explain why the same institutional forces that suppressed chiropractic care and natural medicine buried this practice for over a century. They break down how near-infrared light penetrates the body to charge water into a more bioavailable state, boost glutathione and melatonin production, and repolarize cellular voltage for better metabolism and longevity. The conversation also covers why blue light from LEDs devastates hormones, testosterone, and fertility, how EMF exposure silently drains human performance, and why grounding and Faraday shielding matter more than most supplements on the market. You'll Learn: Why near-infrared light functions as an essential nutrient your body cannot make without it How light physically restructures water to improve mitochondria function and cellular energy The suppressed history of Dr. Kellogg's incandescent light therapy and why it disappeared How blue light exposure crashes testosterone and disrupts fertility and hormone regulation Why EMF shielding and grounding are critical, overlooked tools for longevity and recovery How to use infrared light like a daily supplement instead of an occasional treatment Why carnivore-adjacent, nutrient-dense eating pairs naturally with light and heat therapy Thank you to our sponsors! - ELITE Performance Coaching | If you'd like to discover where you may be addicted to struggle, allergic to success, and what may be standing between you and your next breakthrough, visit FastestChange.com - Longevity Farms | Go to getlongevityfarms.shop. Use code DAVE for 20% off your next order. - Calroy | Go to calroy.com/dave for the clinical research, your discount, and a 45-day money-back guarantee. - PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Brian Richards, SaunaSpace, incandescent light therapy, near-infrared light, FireLight Spectrum, Dr. John Harvey Kellogg, Light Therapeutics, exclusion zone water, Gerald Pollack, EMF shielding, Faraday cage, grounding mat, earthing, redox potential, mitochondrial energy, glutathione, melatonin, blue light toxicity, circadian biology, red light therapy, heat shock proteins, vitamin D, sun callus, Danger Coffee, Flexner Report, testosterone, biophotons Resources: • Go to https://sauna.space/ and use code ‘Dave' for a 15% discount! • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15? • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 00:46 – Meet Brian Richards 03:17 – Kellogg's Light Bath History 09:04 – Persecuted Light Pioneers 12:47 – Near-Infrared Science 16:07 – Blue Light Damage 19:26 – Sunscreen Myths 23:52 – Antidote & Melatonin 33:24 – Exclusion Zone Water 37:52 – Heart as a Vortex 41:47 – Fireplace & Infrared Deficiency 46:15 – FireLight Bulb Design 51:52 – EMF Shielding 55:16 – Faraday Cage & Grounding 1:05:51 – Sauna.Space Discount See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.