Podcast appearances and mentions of Sharon K Inouye

Dr. Sharon K. Inouye is the Director of the Aging Brain Center at the Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife in Boston, Massachusetts ( https://www.marcusinstituteforaging.org/scientists/team-profiles-and-bios/sharon-k-inouye-md-mph ). Dr. Inouye has an M.D., from University of California San Francisco and M.P.H. from Yale and currently holds the Milton and Shirley F. Levy Family Chair and is a Professor of Medicine at Harvard Medical School (Beth Israel Deaconess Medical Center). Her research focuses on delirium and functional decline in hospitalized older patients, resulting in more than 300 peer-reviewed original articles to date. Dr. Inouye is the principal investigator of the Successful Aging after Elective Surgery (SAGES) study, an $11 million Program Project on delirium funded by the National Institute on Aging whose purpose is to examine the interface of delirium and dementia, whether delirium alters the course of dementia, and whether delirium leads to longstanding cognitive impairment and pathologic changes in the brain. Dr. Inouye developed and validated the Confusion Assessment Method (CAM), the most widely-used instrument for the identification of delirium. She conceptualized the multi-factorial model for delirium, which focuses on identification of predisposing and precipitating factors for delirium and her work involves translating theories of clinical investigation into practical applications that directly improve the quality of life for older adults. Dr. Inouye has also developed the Hospital Elder Life Program (HELP), a multi-component intervention strategy designed to prevent delirium by targeting six delirium risk factors. HELP was successful in reducing delirium by 40 percent and was published in a landmark study in the New England Journal of Medicine. This study was the first to show that a substantial proportion of delirium is preventable. Additionally, HELP has been shown to reduce falls, functional decline, and hospital costs, and to improve patient, family, and nursing satisfaction. The HELP program has been adopted by hundreds of hospitals worldwide. Dr. Inouye has been awarded many of the highest accolades in her field, including being elected to the Institute of Medicine of the National Academies.

Dr. Sharon K. Inouye discusses her paper entitled, "Joining Forces against Delirium — From Organ-System Care to Whole-Human Care". You can read the full paper here: https://www.nejm.org/doi/full/10.1056/NEJMp1910499     

Ira Pastor, ideaXme life sciences ambassador, interviews Dr. Sharon K. Inouye, Professor of Medicine, Harvard Medical School and Director of the Aging Brain Center at the Hinda and Arthur Marcus Institute for Aging Research at Hebrew Senior Life. Ira comments: Today we are going to touch on a topic that we have not yet discussed on previous episodes, and that’s the topic of delirium, a serious disturbance in mental abilities that results in confused thinking and reduced awareness of the environment, which in contrast to dementia, which is a very chronic and progressive condition, delirium is a very acute, emergent condition, and it can be very shocking for loved ones and medical practitioners alike. Recent studies indicate that delirium is common for older persons in the hospital setting, with occurrence rates ranging from 29-64%. Delirium is associated with: increased morbidity and mortality, functional and cognitive decline, increased rates of dementia, institutionalization, caregiver burden, and extreme costs in the hundreds of billions. Most shockingly, delirium is often unrecognized. Studies have shown that in affected persons, that delirium is only recognized by about only 1/3 of physicians and nurses. Today on the show, we are joined by Dr. Sharon K. Inouye, Director of the Aging Brain Center at the Hinda and Arthur Marcus Institute for Aging Research, Hebrew Senior Life, in Boston, Massachusetts. Dr. Inouye has an M.D., from University of California San Francisco, and an M.P.H. from Yale, currently holds the Milton and Shirley F. Levy Family Chair and is a Professor of Medicine at Harvard Medical School (Beth Israel Deaconess Medical Center). Her research focuses on delirium and functional decline in hospitalized older patients, resulting in more than 300 peer-reviewed original articles to date. Dr. Inouye's Work Currently, Dr. Inouye is the principal investigator of the Successful Aging after Elective Surgery(SAGES) study, an $11 million project on delirium funded by the National Institute on Aging, whose purpose is to examine the interface of delirium and dementia, whether delirium alters the course of dementia, and whether delirium leads to long standing cognitive impairment and pathologic changes in the brain. Dr. Inouye developed and validated theConfusion Assessment Method (CAM), the most widely used instrument for the identification of delirium. She conceptualized the multi-factorial model for delirium, which focuses on identification of predisposing and precipitating factors for delirium, and her work involves translating theories of clinical investigation into practical applications that directly improve the quality of life for older adults. She has also developed the Hospital Elder Life Program (HELP), a multi-component intervention strategy designed to prevent delirium by targeting six delirium risk factors. HELP was successful in reducing delirium by 40 percent and was published in a landmark study in the New England Journal of Medicine. This study was the first to show that a substantial proportion of delirium is preventable. Additionally, HELP has been shown to reduce falls, functional decline, and hospital costs, and to improve patient, family, and nursing satisfaction. The HELP program has been adopted by hundreds of hospitals worldwide. Dr. Inouye has been awarded many of the highest accolades in her field, including being elected to the Institute of Medicine of the National Academies. On this show we will hear from Dr. Inouye about: Her background, how she became interested in medicine, in public health and how she became interested in this widely un-diagnosed area of brain aging. Her recent paper “Joining Forces against Delirium — From Organ-System Care to Whole-Human Care” in the New England Journal of Medicine (NEJM) where she describes her own personal findings with her father in a hospital with delirium following a collapse and emergency surgery, where specialty teams overseeing his care did not work with a unified approach. An overview of the HELP protocol in the New England Journal of Medicine (NEJM) - "A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients." A discussion of the delirium – Alzheimer’s connection. An overview of the state of pharmacological intervention for delirium. A discussion of the "end-of-life" states of terminal lucidity and terminal agitation / delirium. Credits: Ira Pastor Follow Ira Pastor on Twitter:@IraSamuelPastor Follow ideaXme on Twitter:@ideaxm On Instagram:@ideaxme Sponsor ideaXme on Patreon! Find ideaXme across the internet including on iTunes,SoundCloud,Radio Public,TuneIn Radio,I Heart Radio, Google Podcasts, Spotify and more. ideaXme is a global podcast, creator series and mentor programme. Our mission: Move the human story forward!™ ideaXme Ltd.

The 2015-2016 Humanism in Aging Leadership Award winner is: Sharon K. Inouye, M.D., M.P.H. Feveloped the Confusion Assessment Method, a widely used method for delirium screening, translated into more than 14 languages and the Hospital Elder Life Program (HELP) for delirium prevention, which has been implemented in more than 200 hospitals worldwide. Director of the Successful AGing after Elective Surgery (SAGES) study, a large program project from the National Institute on Aging exploring innovative risk factors and long-term outcomes of delirium. Authored more than 220 scientific articles Elected to the Institute of Medicine in 2011