Podcasts about aging research

Deborah Kado is a geriatrician who believes her field is misunderstood. Her interest in the science of aging began with a childhood encounter in a nursing home but recently resulted in intriguing work in which Kado linked microbes in the gut to vitamin D metabolism and poor sleep. Kado refuses to blame aging alone for health problems, advocating for better care regardless of age. It's never too late to strive for better health, Kado tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Deborah KadoConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Deborah Kado, a professor of medicine and epidemiology at Stanford University.(00:03:22) Origin Story in GeriatricsHow a childhood encounter led to Deborah's career in geriatrics.(00:06:04) Geriatrics vs. GerontologyThe clinical and research distinctions between the two related fields.(00:06:58) Rethinking AgingReframing aging as a lifelong process rather than decline and loss.(00:08:34) Patient Care ApproachWhy symptoms should be investigated, not dismissed as inevitable aging.(00:11:33) Linking Bone Health, Gut, and BrainThe surprising relationship between microbiomes, bones, and cognition.(00:14:34) Vitamin D: Storage vs. Active FormWhy only the active form of vitamin D correlates with microbiome health.(00:17:22) Gut Health and SleepHow better sleep quality is linked to healthier microbiomes.(00:21:20) Medical Education & Geriatric TrainingThe shortage of geriatrics training in U.S. medical schools.(00:23:08) Measuring Geriatric KnowledgeThe challenges and efforts to measure student knowledge about aging.(00:27:24) Takeaways for Medical ProfessionalsTwo anecdotes where symptoms were misattributed to old age.(00:30:51) Empowering Aging PatientsAdvice to aging individuals: agency, purpose, and not settling for less care.(00:34:02) Conclusion  Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

Send us a textIn this episode of Causes or Cures, Dr. Eeks chats with aging and longevity expert Dr. Heike Bischoff-Ferrari about whether simple lifestyle interventions, like supplementation and exercise, can actually make us biologically younger.Dr. Bischoff-Ferrari breaks down: • What DNA methylation clocks are and how they're used to measure biological age • The design and findings of the DO-HEALTH Bio-Age Trial • Whether vitamin D, algae-based omega-3s, and exercise can turn back your biological clock • The science behind how these interventions may work • Practical takeaways for longevity and healthy aging • What's next in this fast-moving fieldDr. Bischoff-Ferrari is a physician and researcher with board certifications in geriatrics, internal medicine, and rehab. She's a professor at the University of Zurich where she chairs the Department of Geriatrics and Aging Research, and the principal investigator of DO-HEALTH, Europe's largest study ever on healthy longevity. With a doctorate from Harvard and a long-standing commitment to aging research, she's at the forefront of understanding how to extend not just lifespan, but healthspan. You can learn more about her here. You can contact Dr. Eeks at bloomingwellness.com.Follow Eeks on Instagram here.Or Facebook here.Or X.On Youtube.Or TikTok.SUBSCRIBE to her monthly newsletter here.Support the show

WPRB News and Culture: The Pidgin has growing pains, and we can feel ourselves aging like fine wine, so today we're talking seniority – in all the meanings of the word. We talk about the elders in our lives, and our communities, but we're also thinking about chapters ending and beginning. Ariel Chen starts us off by reporting on this past week's May Day protests in the community, and points to how older people are starting to become the new face of activism. For our culture segment, Margo Mattes reflects on personal stories from the drama of her grandmother's nursing home, and reflects on how the way we feel, and interact with other people, never really changes as we move through life. Finally, for our science segment, Teo Grosu and Natalia Maidique talk to Dr. Coleen Murphy, a researcher at Princeton who studies aging in many forms, about how research often needs the space to grow and age for its true importance to be revealed.Hosted and produced by Teo Grosu and Natalia Maidique. Reported, recorded, and produced by Ariel Chen, Margo Mattes, Teo Grosu, and Natalia Maidique.All music used under Creative Commons license.(00:00) Introduction(01:35) May Day Protests(15:03) Acting Your Age(24:50) Aging Research

Send us a textIn this episode of Causes or Cures, Dr. Eeks chats with Dr. Amir Baniassadi about how indoor temperature affects the aging brain.Dr. Baniassadi shares what we know so far about the relationship between temperature and cognitive function, and explores the theories behind how temperature might influence cognition as we age. He discusses the findings of his recent study on temperature and cognition, including what surprised his team most. He also touches on an earlier study he conducted on temperature and sleep, and offers practical tips for optimizing your home environment. Is there a “sweet spot” for room temperature that supports both clear thinking and better sleep?Dr. Baniassadi is an instructor of medicine at Harvard Medical School and a scientist at the Marcus Institute for Aging Research. His work focuses on the aging brain and how environmental factors affect health and well-being in older adults. He holds a PhD in Civil, Environmental, and Sustainable Engineering from Arizona State University and an undergraduate degree in Mechanical Engineering from the University of Tehran. He also completed postdoctoral training in Translational Research in Older Adults, as well as a fellowship at the Harvard Graduate School of Design.Learn more about his work here. You can contact Dr. Eeks at bloomingwellness.com.Follow Eeks on Instagram here.Or Facebook here.Or X.On Youtube.Or TikTok.SUBSCRIBE to her monthly newsletter here.Support the show

This video explores a comprehensive review published in the journal Nutrients focusing on Astragalus membranaceus and its potential role in delaying aging. What's fascinating is the breadth of mechanisms discussed: the review highlights how active phytochemicals in Astragalus root – like specific polysaccharides, flavonoids, and saponins – exert powerful antioxidant, anti-inflammatory, and immune-regulating effects. These properties are linked to protecting cells from damage and dysfunction associated with aging. The review specifically points to benefits for skin health, suggesting these compounds may help maintain skin condition and prevent tissue degeneration. Beyond the skin, the research surveyed indicates potential protective effects across multiple body systems – including the cardiovascular, nervous, and immune systems – painting a picture of Astragalus as a multifaceted agent in promoting healthspan and potentially slowing the aging process at a cellular level.Disclaimers:"This information is based on a scientific review article summarizing existing research and is for educational purposes only. It is not medical advice.""This review covers a range of studies (potentially including human, animal, and cell-based research). Consult the original review article for details on the sources of evidence. Further research is often needed.""Always consult a qualified healthcare professional before using Astragalus supplements or making changes to your health plan. Astragalus can interact with medications and may not be suitable for everyone, especially those with certain medical conditions.""This channel is not monetized and does not provide medical advice."#AstragalusMembranaceus #CellularAging #SkinAging #Astragalus #PhytochemicalsBorowicz KK, Jach ME. Astragalus Membranaceus—Can It Delay Cellular Aging? Nutrients. 2025; 17(8):1299. https://doi.org/10.3390/nu17081299Astragalus membranaceus,cellular aging,review,anti-aging,traditional Chinese medicine,antioxidants,flavonoids,saponins,polysaccharides,immunomodulation,inflammation,skin health,longevity,phytotherapy,herbal remedies,natural supplements,oxidative stress,senescence,gerontology,nutrients journal,adaptogen,cardiovascular health,immune support,regenerative medicine,systemic effects

Send us a textDr. Courtney Millar, Ph.D. ( https://www.marcusinstituteforaging.org/who-we-are/profiles/courtney-millar-phd ) is an Assistant Scientist at the Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, and Instructor in Medicine, Harvard Medical School and Beth Israel Deaconess Medical Center.Dr. Millar is a research scientist devoted to improving health and well-being of older adults through dietary interventions and her current research aims to test the ability of anti-inflammatory dietary strategies that promote both physical and emotional well-being in older adults.Dr. Millar received her PhD in molecular nutrition at the University of Connecticut, where she developed a deep understanding of the relationship between dietary bioactive components and metabolic disease. Dr. Millar's post-doctoral fellowship focused on training related to conducting both nutritional epidemiological analyses and clinical interventions. The Hinda and Arthur Marcus Institute for Aging Research ( https://www.marcusinstituteforaging.org/ ) is focused on finding solutions to the most pressing challenges of aging, including Alzheimer's disease, dementia, osteoporosis, falls, frailty, and more.Important Episode Link - Tart Cherry Research Study - https://studies.buildclinical.com/bcfs001399-hsl-millar-79#CourtneyMillar #MarcusInstitute #AgingResearch #HebrewSeniorLife #HarvardMedicalSchool #BethIsraelDeaconess #MolecularNutrition #BioactiveCompounds #Atherosclerosis #Frailty #Inflammation #Senolytics #Dasatinib #Quercetin #Microbiome #TartCherryJuice #Alzheimers #Dementia #Lipid654 #Healthspan #Geroscience #Longevity #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #ViralPodcast #STEM #Innovation #Technology #Science #ResearchSupport the show

Aging Research in Women takes center stage as Dr. Jennifer Garrison uncovers the overlooked reality that ovaries age faster than any other organ. This rapid aging, occurring at a rate two and a half times quicker than other tissues, significantly impacts women's health spans. From heightened cardiovascular risks to osteoporosis, the consequences of accelerated ovarian aging are vast, especially post-menopause. Yet, ovarian health research has long suffered from severe underfunding. At the Buck Institute for Research on Aging, Garrison's work aims to address this deficit by understanding the brain-ovary signaling axis, which she believes is key to promoting healthier aging for women. Sponsored by Qualia Senolytic: https://qualialife.com/podcastoffer. Use code podcast when you shop Qualia Senolytic for 15% off your order. Get in touch. Instagram: https://www.instagram.com/qualialife. Facebook: https://www.facebook.com/qualialife. Email: support@qualialife.com.

This episode is brought to you by  Bon Charge and Momentous. We used to think circadian rhythm only applied to sleep. But emerging science has revealed a link between our circadian rhythm and metabolism, cognition, risk for chronic diseases, and many other crucial aspects of our health. Our biology was designed to live in sync with a natural light-dark cycle, but modern-day society has disrupted this natural balance.  Today on The Dhru Purohit Show, we're revisiting one of our favorite episodes with Dr. Satchin Panda. Dr. Panda dives deep into his groundbreaking circadian biology research and shares how leveraging your circadian rhythm can dramatically improve your sleep, lower your risk of chronic disease, and improve your cognitive function. They also discuss how time-restricted eating, exercise, and light can be used to help program your circadian rhythm and why it's especially important for shift workers to take advantage of these tools.  Dr. Panda is pioneering circadian biology research. He is a professor at the Salk Institute for Biological Studies, a Pew Biomedical Scholar, founder of the UC San Diego Center for Circadian Biology, and recipient of the Julie Martin Mid-Career Award in Aging Research. Dr. Panda has spoken at conferences around the world about his work on circadian rhythms and diabetes, including Diabetes UK, the American Diabetes Association, the Danish Diabetes Association, and the professional diabetes societies of Europe and Australia. In this episode, Dhru and Dr. Panda dive into: Why late-night eating is so detrimental to our health (2:15) Organ systems that have a circadian rhythm (8:24) Common ailments that could be related to circadian rhythm disturbances (14:11) Night-shift work and cancer risk (20:19) How poor sleep perpetuates bad food choices (27:00) What happens in the body when you rely on an alarm clock (44:01) Why you need to accumulate sleep debt for better sleep (51:25) Time-restricted eating and sleep (1:00:40) How to combat fragmented sleep (1:15:35) The best time to work out (1:55:50) The link between exercise and cancer (2:07:55) Positive changes for better sleep health on a global scale (2:17:20) Strategies for night-shift workers to combat circadian rhythm disruption 02:45:10) Dr. Panda's research in firefighters (2:48:46) Tips for optimizing your circadian rhythm (3:14:20) Where to follow and support Dr. Panda's work (3:27:50) Also mentioned in this episode: The Circadian Code: Lose Weight, Supercharge Your Energy, and Transform Your Health from Morning to Midnight The Circadian Diabetes Code: Discover the Right Time to Eat, Sleep, and Exercise to Prevent and Reverse Prediabetes and Diabetes Download the MyCircadianClock app Try This: 6 Crazy Facts About Sleep Try This: How Exercise Helps Fight Cancer For more on Dr. Satchin Panda, follow him on Twitter @SatchinPanda, Instagram @satchin.panda, or his Website. This episode is brought to you by Bon Charge and Momentous. Right now, BON CHARGE is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%. Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Go to livemomentous.com and enter promo code DHRU to get 20% off any order.  Learn more about your ad choices. Visit megaphone.fm/adchoices

On this episode of Longevity by Design, Dr. Gil Blander speaks with Dr. Michael Ringel, COO of Life Biosciences, about the science of aging and longevity. Michael discusses how evolution influences lifespan and why aging occurs. He explains the trade-off between resource allocation for reproduction versus maintenance and repair within the body. Caloric restriction and its effects on lifespan are explored through an evolutionary lens.Michael highlights the challenges and breakthroughs in longevity research. He touches upon the role of genetics and pharmaceuticals in manipulating lifespan and healthspan. He points to the Pacific rockfish as an example of varying lifespans within a closely related group of species, demonstrating the genetic component of aging. He also notes the impact of Cell reprogramming, referencing a study on how specific Cell reprogramming can regenerate optic nerves.The conversation shifts to the business of longevity, where Michael discusses the increased interest and investments from big pharma and billionaires. He examines the economic benefits of extending healthspan, citing a potential value of $300 trillion from a 10-year healthspan extension in the US alone. Michael and Gil also explore the importance of lifestyle choices for healthy aging, emphasizing diet, exercise, sleep, stress management, and social connections.Guest-at-a-Glance

BUFFALO, NY — February 26, 2025 — A new #research paper was #published in Aging (Aging-US) on January 27, 2025, in Volume 17, Issue 1, titled “Age-invariant genes: multi-tissue identification and characterization of murine reference genes.” Aging is a process driven by changes in gene activity, but researchers from Yale University School of Medicine and Altos Labs, led by first author John T. González and corresponding author Albert T. Higgins-Chen, have identified a set of genes that remain unchanged throughout the aging process. This discovery could improve the accuracy of aging research and provide insights into why some genes stay unchanged while others decline. “Reference genes have mostly been identified and validated in young organisms, and no systematic investigation has been done across the lifespan.” The study looked at gene activity in 17 different tissues in mice, from 1 month old to over 21 months old. Scientists used advanced bioinformatic analysis methods to analyze RNA sequencing data. They found nine genes that stayed the same across all tissues, as well as other genes that remained stable in specific tissues. These genes are usually shorter and have special DNA regions called CpG islands, which may help cells stay healthy and resist aging. Their stability throughout aging was confirmed by analyzing different datasets and using RT-qPCR. One of the most significant findings is that these stable genes are linked to essential cellular functions, such as mitochondrial activity and protein maintenance. This challenges the common belief that all aspects of aging involve gene dysregulation. Instead, the findings suggest that some cellular processes may naturally resist aging, leading the way for new research on longevity and potential anti-aging therapies. “Biological processes that change with age and those that resist age-related dysregulation are two sides of the same coin, and both will need to be investigated to fully understand aging.” Another key finding is that commonly used reference genes, such as GAPDH and ACTB, fluctuate with age, making them unreliable for aging studies. No single classical reference gene was found to be stable across all tissues. Researchers often use these reference genes as a control to measure gene activity, but if their expression changes over time, it can lead to inaccurate results. By identifying new, stable reference genes, this study provides scientists with better tools for studying aging-related diseases, regenerative medicine, and longevity science. Understanding how certain genes remain unchanged throughout life suggests that they may play a protective role in aging and could potentially be used to develop treatments that slow down age-related decline. While further research is needed, this discovery sets a new standard for measuring gene activity in aging studies and could have a significant impact on aging research and medicine. DOI - https://doi.org/10.18632/aging.206192 Corresponding author - Albert T. Higgins-Chen - a.higginschen@yale.edu About Aging-US The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com​​ and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM

In the Season 3 premiere of the Longevity & Aging Series, Dr. Yu-Xuan Lyu from Southern University of Science and Technology (Shenzhen, China) joins host Dr. Evgeniy Galimov to discuss his co-authored research paper, featured as the cover for Aging (Aging-US) Volume 16, Issue 20, titled “Longevity biotechnology: bridging AI, biomarkers, geroscience, and clinical applications for healthy longevity.” #aging #author #interview #series #biotechnology #ai #artificialintelligence #longevity #healthspan #lifespan #oa #openscience #peerreview #journal #publication #publishing #meded #agingshort #video DOI - https://doi.org/10.18632/aging.206135 Corresponding authors - Yu-Xuan Lyu - lvyx@sustech.edu.cn, Alex Zhavoronkov - alex@insilico.com, Morten Scheibye-Knudsen - mscheibye@sund.ku.dk, and Daniela Bakula - bakula@sund.ku.dk Video interview - https://www.youtube.com/watch?v=VUfNxWdBV5k Video short - https://www.youtube.com/watch?v=Hpfe5WJ5g7I Abstract The recent unprecedented progress in ageing research and drug discovery brings together fundamental research and clinical applications to advance the goal of promoting healthy longevity in the human population. We, from the gathering at the Aging Research and Drug Discovery Meeting in 2023, summarised the latest developments in healthspan biotechnology, with a particular emphasis on artificial intelligence (AI), biomarkers and clocks, geroscience, and clinical trials and interventions for healthy longevity. Moreover, we provide an overview of academic research and the biotech industry focused on targeting ageing as the root of age-related diseases to combat multimorbidity and extend healthspan. We propose that the integration of generative AI, cutting-edge biological technology, and longevity medicine is essential for extending the productive and healthy human lifespan. Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206135 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, biotechnology, artificial intelligence, healthy longevity About Aging-US The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com​​ and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM

Transcript with time code:  https://cuttingedgehealth.com/wp-content/uploads/2025/02/Transcript-47-Dr-Venki-Ramakrishnan.pdf   In this episode, Jane interviews Nobel Prize winner Venki Ramakrishnan, a molecular biologist who offers a balanced perspective on the anti-aging field.   Ramakrishnan discusses various promising areas of anti-aging research, including caloric restriction drugs like rapamycin, senolytics to target senescent cells, and stem cell therapies. He emphasizes the importance of clinical trials and cautions against rushing into unproven treatments. The conversation covers lifestyle factors that can promote healthy aging, such as regular exercise, proper nutrition, and maintaining social connections.   Ramakrishnan shares personal insights, including his father's experience of maintaining an active lifestyle until age 99. He also touches on his own career journey and winning the Nobel Prize. Throughout the interview, he stresses the need for a scientific approach to anti-aging research while acknowledging the urgency felt by many to combat aging. The podcast provides a thoughtful exploration of the current state of anti-aging science, balancing excitement for potential breakthroughs with the need for rigorous scientific validation.   *****   Venki Ramakrishnan shared the 2009 Nobel Prize in Chemistry for uncovering the structure of the ribosome. A National Academy of Sciences member, Venki runs his research group at the MRC Laboratory of Molecular Biology in Cambridge, England. From 2015 to 2020, he served as president of the Royal Society, one of the world's oldest scientific organizations. He is the author of the frank scientific memoir Gene Machine: The Race to Decipher the Secrets of the Ribosome and Amazon bestselling book Why We Die: The New Science of Aging and the Quest for Immortality.   *****   Cutting Edge Health podcast website: https://cuttingedgehealth.com/   Cutting Edge Health Social and YouTube:   YouTube channel: youtube.com/@cuttingedgehealthpodcast   Instagram - https://instagram.com/cuttingedgehealthpodcast   Facebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756   Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.   Special thanks to Alan and Maria on the Cutting Edge Health team!    

Send us a textDr. Amir Baniassadi, Ph.D. is an Instructor of Medicine at Harvard Medical School and an Assistant Scientist in Marcus Institute for Aging Research ( https://www.marcusinstituteforaging.org/who-we-are/profiles/amir-baniassadi-phd ) where he works on environmental impacts on health and well-being of older populations. Dr. Baniassadi works on the impacts of ambient air temperature and air quality (both indoors and outdoors) on outcomes related to the health and well-being of physiologically and socioeconomically vulnerable populations. His research applies novel environmental modeling and measurement techniques along with remote and long-term physiological and functional monitoring of individuals to establish relationships between exposure and outcome variables of interest outside clinical lab settings. The ultimate goal of his research is to develop environmental interventions that optimize the environment for health and longevity of older adults.Dr. Baniassadi has a Ph.D. in Civil, Environmental, and Sustainable Engineering from Arizona State University and a B.Sc. degree in Mechanical Engineering from the University of Tehran. His post-doctoral training includes a three-year T32 fellowship in Translational Research in Older adults, and a two-year postdoctoral fellowship at Harvard University Graduate School of Design. #AmirBaniassadi #HarvardMedicalSchool #MarcusInstituteForAgingResearch #EnvironmentalGerontology #VulnerabilityScience #Exposome #Health #WellBeing #Wearables #SmartHome #AgingInPlace #Thermoregulation #HeatIslands #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #Podcasting #ViralPodcast #STEM #Innovation #Science #Technology #ResearchSupport the show

Join BrainStorm host Meryl Comer as she kicks off 2025 with "Rockstar of Science" Dr. Rudy Tanzi, the pioneering Director of Genetics and Aging Research and Director of the McCance Center for Brain Health at Mass General Hospital. Dr. Tanzi delves into the new FDA-approved drugs, early cognitive blood tests, and why treating Alzheimer's should mirror our approach to heart disease by focusing on prevention long before symptoms appear. Drawing from his decades of research, Dr. Tanzi shares his vision for the future: a simple daily pill that could prevent Alzheimer's just like statins prevent heart disease. Whether you are concerned about brain health or fascinated by cutting-edge medical science, this episode offers hope and practical wisdom from one of the field's most influential voices. You don't want to miss it!Support the show

La marche nordique, ou Nordic Walking, est une discipline sportive qui combine la marche rapide avec l'utilisation de bâtons spécialement conçus pour cette activité. Originaire de Finlande, elle a été développée dans les années 1930 comme entraînement estival pour les skieurs de fond. Contrairement à la marche classique, la marche nordique engage l'ensemble du corps, notamment les membres supérieurs grâce à l'utilisation dynamique des bâtons. Les bâtons, tenus dans chaque main, servent à propulser le corps en avant en synchronisation avec les pas, tout en maintenant une posture droite. Cette technique, simple mais efficace, augmente l'effort physique tout en répartissant les contraintes sur plusieurs groupes musculaires. La marche nordique se pratique sur des terrains variés : routes, sentiers ou même chemins forestiers, ce qui en fait une activité adaptable et accessible à tous les âges. La marche nordique offre une multitude de bienfaits pour la santé, tant physique que mentale : 1. Amélioration de la condition cardiovasculaire : La marche nordique augmente la fréquence cardiaque et améliore l'endurance, tout en réduisant les risques de maladies cardiovasculaires. 2. Renforcement musculaire : Contrairement à la marche classique, elle mobilise jusqu'à 90 % des muscles du corps, y compris ceux des bras, des épaules, du dos et des abdominaux. 3. Soulagement des articulations : Les bâtons réduisent l'impact sur les genoux, les hanches et la colonne vertébrale, ce qui la rend idéale pour les personnes souffrant de douleurs articulaires. 4. Amélioration de la posture et de l'équilibre : En sollicitant le haut du corps et en maintenant une posture droite, elle renforce les muscles posturaux. 5. Effet mental positif : Comme toute activité physique en plein air, elle aide à réduire le stress, l'anxiété et améliore le bien-être général. Une étude publiée dans le Journal of Aging Research (2013) a démontré que la marche nordique améliore significativement la capacité physique, la posture et la qualité de vie chez les seniors. Les participants ayant pratiqué cette activité pendant 12 semaines ont montré une augmentation de leur force musculaire, une meilleure coordination et une réduction de la fatigue. En résumé, la marche nordique est une activité complète, douce et accessible qui combine exercice physique et bienfaits psychologiques, adaptée à tous, qu'il s'agisse de débutants ou de sportifs confirmés. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Want to add a healthy habit to your daily routine that is absolutely free and incredibly effective? Looking to reduce insulin resistance and lose visceral fat? Want to boost mental health and improve cognitive function? Look no further than walking! Tune in to hear us unpack the myriad of research-supported benefits.   In this episode, we discuss the incredible benefits of walking, from lowering blood pressure to improving heart rate variability to reducing stress and so much more. Learn about the magic number when it comes to step count, our thoughts on walking in nature vs. on a treadmill, and get practical tips for getting those steps!    Also in this episode:  Naturally Nourished Teas are buy 3 get 1 FREE, use code FREETEA Gift cards at Naturally Nourished Detox Masterclass 1/8 Keto Masterclass 1/15 Walking Pad C2 use code ALIMILLERRD for savings Health Benefits of Walking Lowers Blood Pressure Hypertension: Brisk walking for 30 minutes, five days a week reduces blood pressure (Hypertension, 2020). Improves Cholesterol Levels Cholesterol: Effects on LDL and HDL cholesterol (Journal of the American Heart Association, 2021). Lipid Profiles: Walking improves triglycerides and HDL (Atherosclerosis, 2021). Reduces the Risk of Coronary Artery Disease Coronary Artery Disease Risk: 150 minutes of walking weekly (Circulation, 2022). Enhances Cardiorespiratory Fitness Reduces Systemic Inflammation Systemic Inflammation: Walking lowers CRP and IL-6 (Arteriosclerosis, Thrombosis, and Vascular Biology, 2020). Systemic Inflammation: Walking reduces inflammatory cytokines (The Journal of Endocrinology, 2022). Helps Maintain Healthy Weight and Prevent Obesity Improves Heart Rate Variability Heart Rate Variability: HRV improvement with regular walking (Heart, 2022). Prevents Peripheral Artery Disease Peripheral Artery Disease: Walking improves circulation and function in PAD patients (Journal of Vascular Surgery, 2021). Reduces Resting Heart Rate Enhances Endothelial Function Supports Recovery After Cardiac Events Improves Insulin Sensitivity Insulin Sensitivity: Improvements with post-meal walks (Diabetes Care, 2021). Enhances Glucose Regulation Boosts Fat Oxidation Fat Oxidation: Brisk walking boosts fat metabolism (Journal of Applied Physiology, 2022). Reduces Visceral Fat Reduction of visceral fat after 10,000 steps/day (Obesity, 2021). Promotes Energy Balance Energy Balance: 12,000 steps/day for maintaining weight (Medicine & Science in Sports & Exercise, 2020). Regulates Hormones Related to Metabolism Increases Mitochondrial Efficiency Improves Metabolic Flexibility Prevents Metabolic Syndrome Helps Manage Type 2 Diabetes Mental health Stress Reduction: Nature walks lower cortisol more than treadmill (Environmental Research, 2022). Stimulates Neurogenesis and Brain Plasticity Brain Connectivity: Walking improves default mode network activity (Journal of Aging Research, 2021). Enhances Neurotransmitter Balance Supports Autonomic Nervous System Regulation Improves Sensory Integration Vestibular Function: Enhancing balance and stability with walking (Frontiers in Neuroscience, 2021). Strengthens Cognitive Function Neurogenesis and Cognitive Function: Exercise-induced brain growth (Nature Neuroscience, 2021). Promotes Myelination and Nerve Health Enhances Emotional Regulation via the Vagus Nerve Reduces Neurological Disease Risk Synchronizes the Nervous System Through Rhythmic Movement Improves Sleep and Circadian Rhythm Bone and Joint Health Immune System Support Longevity and Reduced Mortality Gut Health Gut Health: Positive effects on microbiota diversity (Gut Microbes, 2020). The Science of Step Counts Thoughts on Nature vs. Treadmill Walking Cognitive Benefits: Nature walking improves attention restoration (Nature Neuroscience, 2021). Proprioception: Benefits of uneven terrain in natural settings (Journal of Sports Medicine, 2023). Motivation: Outdoor walkers maintain habits better than treadmill users (Behavioral Medicine, 2022). Immune Boosting: Increased NK cell activity in forest walkers (International Journal of Environmental Health Research, 2021).   Sponsors for this episode:  According to extensive research by the Environmental Working Group, virtually every home in America has harmful contaminants in its tap water. That's why you've got to check out AquaTru. AquaTru purifiers use a 4-stage reverse osmosis purification process, and their countertop purifiers work with NO installation or plumbing. It removes 15x more contaminants than ordinary pitcher filters and are specifically designed to combat chemicals like PFAS in your water supply. Naturally Nourished Podcast listeners can use code ALIMILLERRD at AquaTru.com to save 20% off. 

In this episode of the Healthy, Wealthy, and Smart Podcast, host Dr. Karen Litzy welcomes Phyllis Greenberger, co-founder and CEO of the Society for the Advancement of Women's Health Research. They delve into the longstanding issue of bias and discrimination in women's healthcare, a problem that has persisted for centuries. Phyllis shares insights into the historical context of women's health, highlighting how women were often viewed solely in terms of their reproductive capabilities and deemed too fragile for broader roles in society. This conversation sheds light on the systemic challenges faced by women, particularly minority women, in accessing equitable healthcare. Tune in for an enlightening discussion on the fight to overcome these barriers and improve health outcomes for all women.   Time Stamps:  [00:02:06] Discrimination in women's healthcare. [00:08:07] Women in clinical trials. [00:09:11] Women's health research disparities. [00:15:37] Women's health legislation progress. [00:21:49] Women's inclusion in research. [00:24:32] Heart health awareness for women. [00:30:06] Women's health advocacy in medicine. [00:34:55] Clinical trial accessibility improvements. [00:35:50] Women's health advocacy challenges. [00:40:28] AI and sex differences in research. [00:44:49] Don't take no for an answer.   More About Phyllis Greenberger M.S.W.: Phyllis Greenberger is senior vice president of Science & Health Policy for Healthy Women. Previously, Phyllis was the president and CEO of the Society for Women's Health Research (SWHR), a national nonprofit organization widely recognized as the thought leader in women's health research, for 26 years. Phyllis was awarded the Trailblazer Award by the U.S. Department of Health and Human Services Office of Women's Health in 2016 and the Perennial Hero Award by the Alliance for Aging Research in 2021. Most recently, she received the Women in Government Relations Lifetime Achievement Award and has published a book, Sex Cells, about the fight to overcome bias and discrimination in women's healthcare.   Resources from this Episode: Website Sex Cells the Book Phyllis on LinkedIn Phyllis on Facebook Phyllis on Instagram Phyllis on X   Jane Sponsorship Information: Book a one-on-one demo here Mention the code LITZY1MO for a free month   Follow Dr. Karen Litzy on Social Media: Karen's Twitter Karen's Instagram Karen's LinkedIn   Subscribe to Healthy, Wealthy & Smart: YouTube Website Apple Podcast Spotify SoundCloud Stitcher iHeart Radio

Aging (Aging-US) was a proud sponsor of the “Future of Aging Research Mixer 2024” hosted by the Aging Initiative at Harvard University on November 15 in Boston. This event united a vibrant community of students, researchers and technologists, all driven by a shared mission: advancing innovations in aging research and longevity science. Key Highlights from the Future of Aging Research Mixer 2024 The event kicked off with inspiring opening remarks and a keynote by George Church, professor at Harvard Medical School, founding member of the Wyss Institute, and co-founder of over 50 biotech companies. He was joined by Kat Kajderowicz, an MIT PhD student and Principal at age1. Together, they highlighted the interdisciplinary nature of aging research and its immense potential to drive transformative advancements. Jesse Poganik, HMS Instructor in Medicine and Executive Co-Director of the Biomarkers of Aging Consortium, discussed the evolution of aging science and the critical role biomarkers play in understanding aging processes and assessing the effectiveness of interventions aimed at slowing or reversing age-related changes. Alex Colville, co-founder and general partner at age1, explained how venture capital can accelerate innovation in longevity biotechnology. He shared career advice for aspiring researchers and paid tribute to his mentor, Dr. David Sinclair, a pioneer in aging research. These talks highlighted the importance of mentorship, interdisciplinary collaboration, and investment in driving progress in the aging research field. Read the full summary - https://aging-us.org/2024/11/agings-commitment-to-advancing-research-sponsoring-the-future-of-aging-research-mixer/ About Aging-US The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com​​ and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Welcome to the Green Rush, a weekly conversation at the intersection of cannabis, psychedelics, the capital markets, and culture, produced by KCSA Podcast Labs. Today, we have a special episode featuring our newest production, Alternatively Speaking. In our debut season, we're diving into a revolutionary concept in health span, longevity, and healthcare. We met with Dr. Nir Barzilai, director of the Institute for Aging Research at the Albert Einstein College of Medicine and the Director of the Paul F. Glenn Center for the Biology of Human Aging Research and of the National Institutes of Health's (NIH) Nathan Shock Centers of Excellence in the Basic Biology of Aging. Dr. Barzilai discovered the first “longevity gene” in humans. His research established that the gene variant that leads to high HDL, or “good cholesterol,” is linked to healthy aging and extreme longevity.  Treatments for age-related diseases like type 2 diabetes are being developed based on Dr. Barzilai's work and are currently in clinical trials. In addition to his “longevity gene” research, Dr. Barzilai studies key mechanisms involved in the biology of aging, including how nutrients and genetics influence lifespan. He is also investigating the physical and mental declines associated with aging and how they affect longevity. Dr. Barzilai is professor of medicine (endocrinology) and of genetics, a member of the Diabetes Research Center, and director of the Diabetes Research and Training Center's Animal Physiology core. Podcast Highlights: Introduction & Dr. Nir Barzilai's Groundbreaking Discovery (00:00 - 03:15): Overview of Dr. Nir Barzilai's discovery of the first “longevity gene” in humans and its link to healthy aging. Discussion on the significance of high HDL cholesterol and how it relates to extreme longevity. The Science Behind Longevity Genes (03:16 - 08:32): Dive into the specific genetic markers that contribute to longevity. Dr. Barzilai shares insights on the mechanisms of aging and the potential to delay or reverse age-related diseases. Current Clinical Trials on Age-Related Diseases (08:33 - 12:10): An exploration of the treatments for type 2 diabetes and other age-related conditions that are being developed from Dr. Barzilai's research, with an update on the progress of these clinical trials. Nutritional and Genetic Influence on Lifespan (12:11 - 17:48): How both genetics and nutrition shape our healthspan and longevity. Dr. Barzilai explains the latest findings on how diet can influence aging and the role of genetics in extending life. Mental and Physical Decline in Aging (17:49 - 21:22): Discussion on the common declines in physical and mental health with aging, and how they impact longevity. Dr. Barzilai talks about ongoing research into mitigating these declines. Future of Longevity Research (21:23 - 26:55): Dr. Barzilai shares his vision for the future of aging research, focusing on potential breakthroughs in longevity science. Social Media: @NirBarzilaiMD: https://x.com/nirbarzilaimd?lang=en  https://www.linkedin.com/in/nir-barzilai-7a86a7212/  Other Links/Mentions/Resources: Age Later by Nir Barzilai, M.D. https://us.macmillan.com/books/9781250230867/agelater  Albert Einstein College of Medicine https://einsteinmed.edu/faculty/484/nir-barzilai  American Federation for Aging Research (AFAR) https://www.afar.org/ Aging is a Treatable Condition - Worth.com The 4 most promising anti-aging drugs investors are sleeping on, according to a leading longevity researcher - Business Insider What is your Biological Age? - The New York Times Show Credits: This episode was hosted by Anne Donohoe and Phil Carlson of KCSA Strategic Communications.  Special thanks to our Program Director, Shea Gunther, and Executive Producer, Maria Petsanas. You can learn more about how KCSA can help your cannabis and psychedelic companies by visiting www.kcsa.com or emailing greenrush@kcsa.com.

BUFFALO, NY- October 31, 2024 – A new #research paper was #published as the #cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 20, entitled, “Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.” This paper summarizes recent advances in healthspan biotechnology discussed at the 2023 Aging Research and Drug Discovery Meeting (ARDD), where leading experts reviewed breakthroughs in artificial intelligence (AI), biomarkers, aging clocks, geroscience, and clinical trials that support healthier, longer lives. The authors present a comprehensive view of how these technologies are shaping research and industry approaches to aging, focusing on targeting aging itself to reduce multiple age-related diseases and extend the healthy years of life. With people living longer, addressing age-related health issues is more critical than ever. Traditional healthcare often treats age-related diseases individually, overlooking aging as a core issue. Longevity biotechnology seeks to change this by combining AI with biomarker analysis to detect early signs of aging, enabling targeted interventions that not only delay disease but also promote longer, healthier lives. Led by corresponding authors Yu-Xuan Lyu from Southern University of Science and Technology Shenzhen; Alex Zhavoronkov from Insilico Medicine AI Limited, Masdar City, Abu Dhabi; Morten Scheibye-Knudsen and Daniela Bakula from the Center for Healthy Aging, University of Copenhagen, this research synthesizes the potential of AI to identify precise biomarkers of aging, supporting the development of "aging clocks"—tools that use biological data to estimate a person's biological age and health risks. These tools help clinicians tailor prevention and treatment to individual needs. Additionally, AI speeds up the discovery of drugs that target primary aging drivers, such as cellular damage and decreased cellular energy, offering the potential to slow, prevent, or even reverse certain effects of aging and enhance quality of life. “The fusion of AI with biomarker research has markedly revolutionized the way biomarkers are identified and validated in the field of ageing.” This approach not only promises to slow, prevent, or even reverse certain effects of aging but also emphasizes the potential for AI-driven methods to extend healthspans. In conclusion, the authors emphasize the need for continued investment in AI-driven therapies and biomarker research, which hold the potential to redefine aging care and improve health outcomes as people grow older. DOI - https://doi.org/10.18632/aging.206135 Corresponding Authors - Yu-Xuan Lyu - lvyx@sustech.edu.cn, Alex Zhavoronkov - alex@insilico.com, Morten Scheibye-Knudsen - mscheibye@sund.ku.dk, and Daniela Bakula - bakula@sund.ku.dk Video short - https://www.youtube.com/watch?v=Hpfe5WJ5g7I Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206135 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, biotechnology, artificial intelligence, healthy longevity About Aging-US The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com​​ and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

A new poll examines presidential preferences for Oklahomans behind bars. Oklahoma researchers get a grant to study exercise and aging.McDonald's is bringing back the Quarter Pounder.You can find the KOSU Daily wherever you get your podcasts, you can also subscribe, rate us and leave a comment.You can keep up to date on all the latest news throughout the day at KOSU.org and make sure to follow us on Facebook, Twitter and Instagram at KOSU Radio.This is The KOSU Daily, Oklahoma news, every weekday.

Dr. David Furman is a key researcher at the Buck Institute for Research on Aging, where he focuses on understanding the underlying mechanisms of aging and chronic diseases, particularly through the lens of the immune system. His research centers around "inflammaging," the concept that low-grade, chronic inflammation contributes to the aging process and the development of age-related diseases like cardiovascular disease, neurodegenerative disorders, and metabolic syndromes. At the Buck Institute, Dr. Furman leads efforts to unravel how immune dysfunction plays a pivotal role in accelerating biological aging. His work integrates systems biology approaches, including advanced computational and bioinformatic tools, to analyze large datasets related to human immunity and inflammation. By understanding how these systems change over time, Dr. Furman aims to identify biomarkers of aging and develop therapeutic strategies to target inflammaging. In addition to his role at the Buck Institute, Dr. Furman is involved in the 1000 Immunomes Project, a large-scale initiative to map the immune systems of individuals across different age groups. This project has contributed significantly to the growing understanding of how the immune system deteriorates with age and how this process may be modifiable through intervention. Dr. Furman's work is influential in the longevity and biotech spaces, and he continues to be a thought leader in the development of anti-inflammatory therapies to extend healthspan and potentially delay the onset of age-related diseases. Timestamps 00:00 Introduction to Inflammation and Longevity 03:06 Understanding Inflammation and Aging 05:52 The Role of Environment in Inflammation 09:14 Ancestral Lifestyle Experiment 12:04 The Importance of Movement and Daily Activity 14:54 Nutrition and Its Impact on Health 18:14 The Future of Aging Research and AI 21:02 The Threat of Microplastics 23:53 Conclusion and Future Directions

Support the show and get 50% off MCT oil with free shipping – just leave us a review on iTunes and let us know!https://podcasts.apple.com/us/podcast/live-beyond-the-norms/id1714886566 What if you could live decades longer while staying healthier and happier? Today, we explore cutting-edge advancements in longevity and practical tips you can apply immediately to improve your health and longevity.Sergey Young, founder of the Longevity Vision Fund, shares his journey into longevity after a high cholesterol diagnosis. Sergey discusses how biotechnology, AI, and medical screenings can extend life and slow down aging. He introduces the "longevity bridge," explaining innovations in gene editing, organ regeneration, and age-reversal drugs that will transform how we manage aging and even reverse biological age. Sergey also covers the rapid advancements in AI-driven drug development and their potential to reduce costs and make life extension more accessible. Are you ready to take control of your health and longevity? Tune in now to discover practical longevity tips and learn more about emerging life-extension technologies!"The most important day of your life each year is not your birthday—it's your medical screening day." ~ Sergey YoungAbout Sergey Young:Sergey Young is a longevity investor and visionary dedicated to extending healthy lifespans and making life-extension technologies accessible to all. He is the founder of the Longevity Vision Fund, which invests in breakthrough technologies aimed at slowing aging, reversing biological age, and improving overall health. Sergey serves on the board of the American Federation of Aging Research and the XPRIZE Innovation Board and has co-created global competitions to address aging. He is also the author of the bestselling book The Science and Technology of Growing Young and has been featured on CNN, Fox News, and Forbes.Resources:Discover the groundbreaking ESS60 molecule, proven to extend life by 90%, at MyVitalC.com.Get Sergey's Book “The Science and Technology of Growing Young”: https://a.co/d/2bmBEc8Connect with Sergey Young:- Website: https://sergeyyoung.com/ - Instagram: https://www.instagram.com/sergeyyoung200/  - LinkedIn: https://ae.linkedin.com/in/sergeyyoung - YouTube: https://m.youtube.com/@sergeyyoung200 Connect with Christopher Burres- Website - https://www.myvitalc.com/- Website - http://www.livebeyondthenorms.com/- Instagram - https://www.instagram.com/chrisburres/- TikTok - https://www.tiktok.com/@myvitalc - LinkedIn - https://www.linkedin.com/in/chrisburres/

Do you prefer multistory episodes, single story episodes, or a mix? Let us know! In this episode of 'Discover Daily' by Perplexity, we begin with a look at Adobe's latest innovation, the Firefly Video Model. This AI-powered toolset boasts video editing features like Generative Extend,  now available in beta in Premiere Pro, and offers commercial safety and ethical considerations that may set it apart from competitors. We then shift to recent findings in longevity research, revealing that human life expectancy gains are slowing down and potentially approaching a biological limit. We discuss the implications of this research, including the concept of "healthspan" and the importance of quality of life over mere quantity of years. The episode's main focus is on NASA's Europa Clipper mission, which launched on October 14, 2024. The ambitious project will explore Jupiter's icy moon Europa, potentially one of the most promising places in our solar system to search for extraterrestrial life. We discuss the mission's objectives, the spacecraft's innovative design features, and the potential implications of discovering conditions suitable for life beneath Europa's frozen surface. This fascinating exploration of space science highlights the ongoing quest to understand our place in the universe and the potential for life beyond Earth.Perplexity is the fastest and most powerful way to search the web. Perplexity crawls the web and curates the most relevant and up-to-date sources (from academic papers to Reddit threads) to create the perfect response to any question or topic you're interested in. Take the world's knowledge with you anywhere. Available on iOS and Android Join our growing Discord community for the latest updates and exclusive content. Follow us on: Instagram Threads X (Twitter) YouTube Linkedin

On tonight's show, I have two guests. My first guest is Sue Peschin, president and CEO of the Alliance for Aging Research. She will be sharing about the importance of our older population protecting themselves against RSV as we face the fall/winter season. Ahead of National Leave a Review Day, I'll have Joe Burton, CEO of Reputation. Joe will be sharing about the importance of online reviews.

RSV is a common infectious respiratory virus that usually causes cold-like symptoms but can lead to serious illness or even death. Sue Peschin, CEO and President of the Alliance for Aging Research and Dr. Robert Hopkins, Jr., Medical Director for the National Foundation for Infectious Diseases share information about the virus.Support WITF: https://www.witf.org/support/give-now/See omnystudio.com/listener for privacy information.

Welcome to the Green Rush, a weekly conversation at the intersection of cannabis, psychedelics, the capital markets, and culture, produced by KCSA Podcast Labs. Today, we have a special edition of the Green Rush featuring our newest production, Alternatively Speaking. In our debut season, we're diving into a revolutionary concept in health span, longevity, and healthcare.  Our hosts sat down with Alternatively Speaking's first-ever guest, Jamie Justice, Executive Vice President of the Health Domain at XPRIZE Foundation and Adjunct Professor in Internal Medicine Section on Gerontology and Geriatric Medicine, and Sticht Center on Healthy Aging and Alzheimer's Prevention at Wake Forest University School of Medicine (WFUSM). Jamie is dedicated to Geroscience research that advances the hypothesis that by targeting the basic biology of aging the incidence of multiple age-related diseases can be delayed or prevented. So don't sit back, lean forward and enjoy! Podcast Highlights: Introduction & XPRIZE Foundation Origins (00:00 - 02:29): Overview of the longevity industry, the impact of the Ansari XPRIZE on private space travel, and XPRIZE's influence on companies like SpaceX. Jamie Justice's Background & Passion for Research (02:30 - 06:14): Jamie's journey into gerontology, early research experiences with older adults, and her focus on empathy and the human aspect of aging. Exploring Aging & Longevity (06:15 - 10:21): Discussion on the fundamental questions of aging, how different interventions (lifestyle, supplements, drugs) impact human health and longevity. Translating Aging Research into Practice (10:22 - 13:10): Jamie's work at Wake Forest, ongoing efforts to apply aging research in real-world settings, and the philosophical aspects of aging—living fully versus focusing on death. Healthspan vs. Lifespan & Longevity Goals (13:11 - 20:43): Exploring the concept of the ‘longevity dividend,' aligning biological health with extended life, and the strategies to improve healthspan by optimizing current biology. XPRIZE HealthSPAN Award & Future of Aging Research (20:44 - 28:28): Introduction to the XPRIZE HealthSPAN Award program, the bold scientific goals it supports, challenges in aging research, and the collaborative efforts to advance the field. Social Media: X: @j_n_justice LinkedIn: https://www.linkedin.com/in/jamie-justice-ph-d-6b933146/  Other Links/Mentions: https://www.xprize.org/  https://www.xprize.org/prizes/healthspan  Show Credits: This episode was hosted by Anne Donohoe of KCSA Strategic Communications.  Special thanks to our Program Director, Shea Gunther and Executive Producer, Maria Petsanas. You can learn more about how KCSA can help your cannabis and psychedelic companies by visiting www.kcsa.com or emailing greenrush@kcsa.com. You can also connect with us via our social channels: X: @KCSAPodcastLabs Instagram: @KCSAPodcastLabs LinkedIn: https://www.linkedin.com/company/kcsapodcastlabs/

Title: Longevity Conferences (ARDD and Dublin Longevity) Quote: “Its not what you know but who you know”Said by many across multiple cultures Today we review:The Aging Research and Drug Discovery Conference in Copenhagen, DenmarkThe Dublin Longevity Summit in Dublin, Ireland 3 Plugs- keep moving until you find your place and your people- go to places where you can be useful and contribute- try not to lose what makes you, you along the way.  Hallmarks of Both Conferences- I highly recommend attending both of these events (and conferences in general)- Europe was a blast. People are out and about. The downtowns I went to were generally flourishing - Work Hard Play Hard – Lots of lectures, lots of late nights at the bar- All Day Every Day- Leaders in the field of Longevity Research (highly research focussed)- Research Focused, Less Clinical (but still some clinical content)- Startups and Funding/Funders was a big focus- Eccentric Personalities- Lots of Fun! Met a lot of great people See full blog post at fullscope.org and longetrics.org

In this episode of the Gladden Longevity Podcast, Steve Reiter and Dr. Gladden explore various aspects of food safety, the concept of regenerative farming, staying young and living young for a lifetime instead of ‘healthy aging', the misconceptions surrounding ‘healthy aging', and the role of self-care in maintaining vitality. The conversation also touches on the latest advancements in aging research and the potential for breakthroughs in longevity science. Dr. Gladden explains why he is so sure that the code on aging will be cracked within the next 3 to 5 years and the cutting-edge technologies being added to Gladden Longevity.   For the audience ·      Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ !     Takeaways   ·      Living young for a lifetime requires mindset work. ·      The food supply is often contaminated with pesticides. ·      Regenerative farming improves food quality by building up the soil. ·      Regenerative farming practices eliminate the need for fertilizers and pesticides. ·      Nutrition and protein quality for muscle maintenance. ·      ‘Healthy aging' is actually NOT the goal. ·      Aging research is rapidly advancing, doubling every three months. ·      Self-care encompasses physical, mental, and spiritual well-being.   Chapters   00:00 Introduction to Age Hacking and Longevity 02:46 The Importance of Mindset in Recovery 04:11 Food Safety and Environmental Toxins 05:38 The Promise of Regenerative Farming 05:56 The Journey of Regenerative Farming 14:17 Redefining Healthy Aging 19:54 Cracking the Code on Aging 24:10 The Importance of Self-Care 26:28 Goodbye   Articles, News and Supplements mentioned Food Safety Education * EXPERTS WANT FDA TO DO MORE TO ENSURE FOOD SAFETY https://www.medpagetoday.com/special-reports/features/111872 * CONSUMERS ARE WEARY OF PESTICIDE RESIDUE IN FRUITS AND VEGETABLES, FIVE-COUNTRY STUDY FINDS https://phys.org/news/2024-09-consumers-wary-pesticide-residue-fruits.amp * FOOD SCIENTIST DEBUNKS 5-SECOND RULE – HERE'S WHAT YOU NEED TO KNOW https://www.delish.com/kitchen-tools/kitchen-secrets/a62138112/five-second-rule-food-science/ * ITEMS THAT DON'T BELONG IN THE FRIDGE https://www.dailymail.co.uk/sciencetech/article-13838551/amp/Can-spot-items-dont-belong-fridge-60-seconds-Half-people-fail-brainteaser.html?ito=smartnews   Healthy Aging * LET THIS 74-YEAR-OLD GRANDMA BE YOUR INSPIRATION FOR HEALTHY AGING https://www.facebook.com/share/v/swAFnup6vvHPwpWV/?mibextid=CTbP7E * WHAT IS GLUTATHIONE, THE ‘NEWEST AGE REVERSAL TREND' – AND GWYNETH PALTROW'S FOUNTAIN OF YOUTH? https://nypost.com/2024/09/11/lifestyle/what-is-glutathione-the-newest-age-reversal-trend-and-gwyneth-paltrows-fountain-of-youth/?utm_source=smartnews&utm_campaign=nypost&utm_medium=referral * THIS OIL IS TOP NOTCH FOR AGING SKIN, ACCORDING TO RESEARCH https://www.mindbodygreen.com/articles/why-moringa-oil-is-for-aging-skin-according-to-research * NUTRITION AND HEALTHY AGING: THE ROLE OF PROTEIN QUALITY IN COMBATING MUSCLE LOSS https://medicalxpress.com/news/2024-09-nutrition-healthy-aging-role-protein.html * DR. GLADDEN'S TOP 3 HACKS FOR LONGEVITY https://www.tiktok.com/t/ZTFLdB7rX/ * MEET THE 62-YEAR-OLD WHO'S AGING BACKWARDS https://youtu.be/qI6aTAicRmw?si=jc1VqhrCm9ZHHkuu   Supplements PERFECT AMINOS https://gladdenlongevityshop.com/products/perfect-amino-coated-tablets-300ct?_pos=2&_psq=perfect&_ss=e&_v=1.0     Send your Qs for future episodes! Email: podcast@gladdenlongevity.com   Reach out to us at: Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw

How do you unlock the mysteries of aging?

Subscribe to our channel: https://www.youtube.com/@optispan Check out Scott Carney's channel: https://www.youtube.com/@sgcarney Related episodes: The True Story of David Sinclair's Longevity Lie: https://www.youtube.com/watch?v=xQrXs7CxIjk DON'T Take Resveratrol Until You Watch This Video: https://youtu.be/MmIBdqsQYfw Scientists Debate How to Live Longer & Longevity Drugs: https://youtu.be/EebH_taOlAA An introduction to the study of RAPAMYCIN: https://youtu.be/czx_-DqnnrQ In this episode, Matt and Nick react to investigative journalist and author Scott Carney's video describing what he calls "David Sinclair's longevity lie" in the context of David's longevity-focused entrepreneurial ventures. Matt shares his professional history with David, including his early interactions with David in Leonard Guarente's lab at the Massachusetts Institute of Technology (MIT) and scientific differences that emerged after Matt and colleagues were unable to reproduce a key result from David's work pertaining to resveratrol. Their discussion touches on some of David's scientific claims about age reversal, the role of institutions such as Harvard University in regulating scientific integrity, the potential for future interventions in healthspan and longevity, and the importance of separating personal feelings from scientific evaluation. David, currently a professor in Harvard Medical School's Department of Genetics at the Paul F. Glenn Center for Biology of Aging Research, is a prominent geroscience researcher whose lab focuses on age-related epigenetic change, cellular reprograming, longevity drug discovery, mitochondrial fitness, reproductive aging, neurodegenerative disease, and the human secretome. He has received awards including the National Institutes of Health Nathan Shock Award, the Merck Prize, and the Australian Medical Research Medal, and was elected to TIME's 2014 “100 Most Influential People in the World" list. David conducted postdoctoral research at MIT and obtained a PhD in Molecular Genetics at the University of New South Wales. Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. More places to find us: Twitter: https://twitter.com/optispanpodcast Twitter: https://twitter.com/optispan Twitter: https://twitter.com/mkaeberlein Linkedin: https://www.linkedin.com/company/optispan https://www.optispan.life/ Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.

“Dr. Admasu earned his PhD in Biochemistry from national university of Singapore. In his PhD work he investigated interactions between lifespan extending drugs with the aim of engineering synergistic benefits in C. elegans. Dr. Admasu is currently a research fellow at SENS Research Foundation. His research focus on isolation and characterization of secondary senescent cells using surface markers and identification of novel approaches to ablate multiple types of senescent cells. He recently identified a novel senolytic approach to kill multiple types of senescent cells.Source: https://www.sens.org/endingagingforum-2022/ About the showThe Learning With Lowell show is a series for the everyday mammal. In this show we'll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn't normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups. Learning with lowell linksYoutube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-QYoutube clips:https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfAWebsite: https://www.learningwithlowell.com/ Tesfahun Admasu linkshttps://www.linkedin.com/in/tessadmasuhttps://scholar.google.com.sg/citations?user=nJA2aaUAAAAJ&hl=enhttps://twitter.com/TessAdmasu Timestamps00:00 Introducing Tesfahun Admasu00:30 Ethiopia Conflict explained18:00 Abiy Ahmed in power21:30 Resolving conflict in Ethiopia23:15 Working for a better Ethiopia27:40 Future of Ethiopia / Abiy Ahmed31:50 Hope for the future of Ethiopia35:40 How can people help Ethiopia39:40 Tesfahun Admasu PhD Singapore / Aging & lifespan Extension47:55 Aging and the Immune system / SENS foundation01:02:08 Non-SENS senolytics trials that you're excited about (FANQ)01:07:05 Book recommendations01:08:33 End comment AgingResearch #EthiopiaConflict #longevity

In this episode of the Veterinary Cancer Pioneers Podcast, Dr. Rachel Venable interviews Dr. Nicole Ehrhart, the Director of the Columbine Health Systems Center for Healthy Aging at Colorado State University. Dr. Ehrhart shares her inspiring journey from her early fascination with surgery to her pioneering work in comparative musculoskeletal oncology and regenerative medicine. She emphasizes the importance of veterinarians having a voice in broader medical and public health conversations, and discusses her innovative research into aging and cancer, highlighting the interconnectedness of these fields. This episode provides an insightful look into Dr. Ehrhart's impactful career and her vision for the future of veterinary and human medicine.

Medicare is betting that taking care of the caregiver will help dementia patients stay at home longer. Patients and their caregivers are often left to navigate the confusing world of dementia by themselves, but Medicare is launching a new program to change that.Guests:Malaz Boustani, MD, PhD, Founding Director, Sandra Eskenazi Center for Brain Care Innovation; Professor of Aging Research, Indiana University School of Medicine Rosanne Corcoran, Caregiver Liz Fowler, PhD, JD, Director of CMMI and Deputy Administrator, Centers for Medicare and Medicaid Services Cindi Hart, Caregiver Alex Olgin, Reporter/Producer, Tradeoffs Lauren Sullivan, Care Coordinator, Eskenazi Health Learn more and read a full transcript on our website.Want more Tradeoffs? Sign up for our free weekly newsletter featuring the latest health policy research and news.Support this type of journalism today, with a gift.Follow us on Twitter. Hosted on Acast. See acast.com/privacy for more information.

Subscribe to our channel: https://www.youtube.com/@optispan Related episodes: These 14 Medications are linked to lower death rates in humans: https://youtu.be/Ju1p_L-2Bq4 Is This The Best Time to Exercise?: https://youtu.be/59SFzLEy6Jg Matt recently attended the 52nd annual meeting of the American Aging Association (AGE) in Madison, Wisconsin and met with several people doing fascinating work in the longevity field. One of these was Berenice Benayoun, an Associate Professor (recently tenured!) of Gerontology, Biological Sciences, Biochemistry, and Molecular Medicine at the University of Southern California Leonard Davis School of Gerontology. Berenice delivered the keynote speech at the 2024 AGE meeting, where she received the 2024 Vincent Cristofalo Rising Star Award in Aging Research. Her research focuses on the influence of genomic regulation mechanisms, environmental stimuli, and factors such as biological sex on vertebrate aging and healthspan. Berenice was named a 2020 Pew Biomedical Scholar and a 2021 Nathan Shock new Investigator, and also received the 2019 Rosalind Franklin Young Investigator Award in Mammalian Genetics, an American Federation of Aging Research Junior Faculty Award, and a Global Consortium for Reproductive Longevity and Equality GCRLE Junior Scholar Award. In this episode, Matt and Berenice chat about the ovaries as a vehicle for understanding aging, the difference between estropause and menopause, and the controversies associated with hormone replacement therapy, and how Berenice made her way into the lab of her dreams. They also discuss the African turquoise killifish, a new vertebrate model organism for longevity research, and address a couple of questions about research we have recently featured on this podcast (how pregnancy affects aging, and sex-specific differences in the effects of estradiol on mouse aging). Producers: Tara Mei, Nicholas Arapis Video Editor: Jacob Keliikoa DISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices. More places to find us: Twitter: https://twitter.com/optispanpodcast Twitter: https://twitter.com/optispan Twitter: https://twitter.com/mkaeberlein Linkedin: https://www.linkedin.com/company/optispan https://www.optispan.life/ Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it. On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!

This week we are going to cover a wide array of research:​ ​Mitophagy's impact on aging (the mitochondria's process of selective degradation of mitochondria by autophagy). If you can't get rid of the garbage mitochondria, that's a rotten deal for your health.   Methylene blue's role in combatting oral biofilm (a sticky film that coats teeth and contains bacteria). Our blue friend may actually be playing a beneficial role by temporarily staining your teeth blue. Who wouldn't trade tooth decay, receding gums and bad breath for that? Preconditioning your muscles for improved muscular strength, endurance and recovery. In reality, how beneficial is this strategy for the active population? Transcranial photobiomodulation for children with autism spectrum disorder. Is this an efficacious treatment for children to mitigate symptoms of ASD? If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key points: Introduction and New Product Announcement (00:00:00 - 00:01:03) BioCream Stock Update (00:01:03 - 00:01:56): Supply exhausted in four days; restock in one to two weeks; updates on BioLight channels. Mitochondria and Aging Research (00:01:56 - 00:06:00): Mitochondrial dysfunction, oxidative damage, inflammation. Autophagy and mitophagy's role in aging. Benefits of Healthy Mitochondria (00:06:00 - 00:11:57): Healthy mitochondria reduce inflammation and slow aging. BioBlue offer: 15% off with code BIOBLUE15. Microbial Biofilms and Infection (00:11:57 - 00:17:00): Photodynamic therapy (PDT) with methylene blue and red LEDs effective in reducing biofilm activity. Methylene Blue's Biocidal Activity (00:17:00 - 00:21:37): Methylene blue's broad biocidal activity; further studies needed for clinical efficacy in biofilm treatment. Preconditioning with Red Light Therapy (00:21:37 - 00:27:07): Enhances muscle performance, brain function, and skin resistance to UV. Meta-Analysis on Red Light Therapy (00:27:07 - 00:32:00) Benefits for Active Individuals (00:32:00 - 00:34:41): Red muscle fibers benefit more from red light therapy. Study on tPBM in Children with ASD (00:36:41 - 00:37:39): Shows safety, efficacy, and symptom improvement. ASD Pathology and tPBM Benefits (00:37:39 - 00:41:37): Brain abnormalities, neuroinflammation, and mitochondrial dysfunction. tPBM Effectiveness and Safety (00:41:37 - 00:45:09): Improves ASD symptoms with specific near-infrared light parameters; safe and effective. tPBM for Early ASD Intervention (00:45:09 - 00:46:52): Potential in treating ASD; early intervention is crucial; further research needed. Encouragement and Future Content (00:46:52 - 00:50:18): Encouragement to review podcast; upcoming expert interviews and red light therapy research. Appreciation and Staying Informed (00:50:18 - 00:51:27): Appreciation for listener support; stay informed on red light therapy benefits. - Articles referenced:   Inflammation and mitophagy are mitochondrial checkpoints to aging   Antimicrobial Activity of Methylene Blue Associated with Photodynamic Therapy: In Vitro Study in Multi-Species Oral Biofilm   Can pre-exercise photobiomodulation improve muscle endurance and promote recovery from muscle strength and injuries in people with different activity levels? A meta-analysis of randomized controlled trials   Transcranial photobiomodulation in children aged 2–6 years: a randomized sham-controlled clinical trial assessing safety, efficacy, and impact on autism spectrum disorder symptoms and brain electrophysiology - Introducing the newest BioBlue product: BioBlue (SR) — a 50/50 blend of methylene blue and leucomethylene blue! For the next week, save 15% on BioBlue (SR) single bottle orders using coupon code "SR15" - Introducing the Red Light Therapy Treatment Protocols Ecosystem! - To learn more about red light therapy and shop for the highest-quality red light therapy products, visit https://www.biolight.shop - Dr. Mike's #1 recommendations: Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn   BioLight: Website Instagram YouTube Facebook

Satchidananda (Satchin) Panda, PhD discusses the impact of food timing on health, advocating for personalized eating windows and gradual changes to fasting routines. Dr. Panda and Dr. Mindy explore the relationship between fasting, metabolic health, and gut microbes, emphasizing the importance of lifestyle factors like sleep, exercise, and diverse gut microbiota for overall well-being. Dr. Panda shares tips on adjusting to different time zones to support metabolic health during travel, highlighting the holistic approach to health through healthy daily routines. To view full show notes, more information on our guests, resources mentioned in the episode, discount codes, transcripts, and more, visit https://drmindypelz.com/ep236 Satchidananda (Satchin) Panda, PhD is a Professor at the Salk Institute in California, where his research focuses on the circadian regulation of behavior, physiology, and metabolism in model organisms and in humans. Dr. Panda discovered a blue-light sensing cell type in the retina entrains our master circadian clock, affects mood, and regulates the production of the sleep hormone melatonin. Recently, he discovered that maintaining a daily feeding-fasting cycle – popularly known as time-restricted feeding (TRF) – can prevent and reverse metabolic diseases. Based on a feasibility study in humans, his lab is currently carrying out a smartphone-based study to assess the extent of circadian disruption among adults. Dr. Panda has received the Julie Martin Mid-Career Award in Aging Research, the Dana Foundation Award in Brain and Immune System Imaging, and was a Pew Scholar in the Biomedical Sciences   Check out our fasting membership at resetacademy.drmindypelz.com. Please note our medical disclaimer.

For decades, Marcus Peter, PhD, has drilled into an area of research focused on cell death and the roles of toxic and protective short RNAs, with the goal of developing a novel form of cancer treatment. Now, this same line of research has led Peter's team to uncover new insights into the cause of Alzheimer's disease. In this episode, Peter explains his pioneering work in investigating RNA interference in diseases and explains how his lab's latest novel discovery may have relevance to an array of neurodegenerative diseases beyond Alzheimer's.

This is a free preview of a paid episode. To hear more, visit www.louiseperry.co.ukMy guest today is Coleen T. Murphy, Professor of Molecular Biology at Princeton, and also the director of Princeton's Laboratory for Aging Research. Her new book is titled 'How We Age: The Science of Longevity.' We spoke about why women live longer than men, what centenarians seem to have in common with one another, why eunuchs may live longer than othe…

The southwest side of Indianapolis will welcome an $11 million affordable housing complex next spring. The number of students who are chronically absent from school surged during the pandemic and remains high. Indiana stopped sharing individual terminated pregnancy reports last December due to patient privacy concerns, but the attorney general and an anti-abortion group say this violates the state's public records reporting law. Older women face a much greater financial burden than their male counterparts as they age – that's one of the takeaways from the Polis Center's State of Aging report. Want to go deeper on the stories you hear on WFYI News Now? Visit wfyi.org/news and follow us on social media to get comprehensive analysis and local news daily. Subscribe to WFYI News Now wherever you get your podcasts. Today's episode of WFYI News Now was produced by Abriana Herron, Drew Daudelin and Kendall Antron with support from News Director Sarah Neal-Estes.

Welcome to another episode of Passive Income Pilots, where we delve into the burgeoning world of assisted living investments. Join hosts Tate Duryea and Ryan Gibson as they discuss the impact of the demographic shift known as the "Silver Tsunami" with Dwayne Clark, founder of Aegis Living. Dwayne shares his extensive experience in building a premier brand in the senior housing industry and provides insights into the challenges and triumphs of caring for the aging population.Timestamped Show Notes:(00:00) - Introduction by Tate and Ryan, discussing the demographic trends boosting assisted living investments.(01:00) - Tate shares a personal story highlighting the immediate relevance of senior care.(02:00) - Ryan introduces Dwayne Clark, highlighting his accomplishments and the ethos of Aegis Living.(04:00) - Dwayne Clark joins the conversation, detailing his journey from the criminal justice field to senior housing.(05:00) - Discussion on the inception of Aegis Living and the challenges of funding and growing a business in senior housing.(07:00) - Dwayne reflects on the sacrifices made to establish Aegis Living, including personal financial risks.(10:00) - Exploring the demographic changes affecting senior housing and the concept of the "silver tsunami."(13:00) - Insights into the supply constraints in senior housing exacerbated by COVID-19 and its impacts on the market.(15:00) - Dwayne shares his philosophy on integrating community history and elements into the design of Aegis facilities.(17:00) - Detailed explanation of different types of senior living and care options available.(20:00) - Discussion on the investment aspects of senior housing and the importance of choosing the right management.(24:00) - Dwayne addresses how families can finance senior living through home equity and other means.(28:00) - Advice for individuals on how to discuss and plan for aging parents' future care needs.(32:00) - Ryan and Tate reflect on the operational excellence at Aegis Living.(35:00) - Dwayne discusses the role of adversity in shaping his career and approach to senior living.(38:00) - Closing thoughts on the current economic climate and its effect on the real estate and senior living sectors.Resources Mentioned:Aegis Living Website: Visit Aegis LivingDwayne Clark's Personal Website: Explore HereDwayne's upcoming book Where's Your Purse: A Guide for Children with Aging Parents details managing aging parent care.Remember to subscribe for more insights at PassiveIncomePilots.com!Join our growing community on FacebookCheck us out on Instagram @PassiveIncomePilotsFollow us on X @IncomePilotsGet our updates on LinkedInHave questions or want to discuss this episode? Contact us at ask@passiveincomepilots.com See you on the next one!Legal DisclaimerThe content of this podcast is provided solely for educational and informational purposes. The views and opinions expressed are those of the hosts, Tait Duryea and Ryan Gibson, and do not reflect those of any organization they are associated with, including Turbine Capital or Spartan Investment Group. The opinions of our guests are their own and should not be construed as financial advice. This podcast does not offer tax, legal, or investment advice. Listeners are advised to consult with their own legal or financial counsel and to conduct their own due diligence before making any financial decisions. The hosts, Tait Duryea and Ryan Gibson, do not necessarily endorse the views of the guests featured on the podcast, nor have the guests been comprehensively vetted by the hosts. Under no circumstances should any material presented in this podcast be used or considered as an offer to sell, or a solicitation of any offer to buy, an interest in any investment. Any potential offer or solicitation will be made exclusively through a Confidential Private Offering Memorandum related to the specific investment.

In this episode of Longevity by Design, host Dr. Gil Blander is joined by Dr. Morten Scheibye-Knudsen, a leading figure in aging research. Dr. Scheibye-Knudsen discusses his groundbreaking research on the role of DNA damage in the aging process and its implications for chronic diseases, aging research, and longevity medicine. The goal of his work is "to discover interventions leading to healthier, happier, and more productive lives."Dr. Scheibye-Knudsen's work is on understanding normal and premature aging, with a focus on the pivotal role of DNA damage in the aging process and interventions for healthier aging. By combining computational methods with laboratory experiments, his team explores innovative strategies to target DNA and counteract aging processes. This conversation illuminates the intricate relationship between DNA damage, aging, and chronic diseases. Dr. Scheibye-Knudsen also discusses the impact of lifestyle (diet, exercise, sleep, social factors) on aging. He goes on to describe his work using data-driven approaches to better understand aging and developing interventions, including identifying novel targets and drugs, for healthier aging. Additionally, he explains what longevity medicine is and the importance of educating clinicians and politicians on this topic to translate research on aging into healthcare and improve people's healthspan and lifespan. Dr. Scheibye-Knudsen's dedication to unraveling the mysteries of aging is advancing scientific knowledge, which has tangible benefits for global health and longevity.Episode timestampsIntroduction: 00:00-03:06What led Dr. Morten Scheibye-Knudsen to become a scientist?: 03:07-04:37Could please give us an overview of the research you are doing?: 04:38-05:54What is DNA damage, and what causes it?: 05:55-07:54What do we know about the influence of DNA damage on aging and age-related diseases?: 07:55-09:41Can DNA damage be repaired? 09:42-14:14What questions are your research group asking to better understand DNA damage and repair and their effects on aging?: 14:15-16:22What is NAD, and why is it relevant to aging and age-related diseases?: 16:23-19:56What are the benefits and risks of NR and NMN supplements in humans?: 19:57-24:50What is a ketogenic diet? What are the effects of a ketogenic diet or ketones on DNA damage or repair and aging?: 24:51-31:08What is the effect of a ketogenic diet on cancer?: 31:09-32:29What is the Aging Research and Drug Discovery (ARDD) conference and its mission?: 32:30-40:43What are the most prevalent features of aging?: 40:44-47:54Are there differences in aging between females and males?: 47:55-50:21Are there differences in tissue aging trajectories?: 50:22-54:01Identifying compounds that target aging: 54:02-56:16Can nuclear morphology predict cellular senescence and cancer?: 56:17-01:04:04What is longevity medicine, and why is it so important for physicians?: 01:04:05-01:07:25What pharmaceutical drugs are the most promising for targeting aging to extend human healthspan and lifespan?: 01:07:26-01:12:00How important are lifestyle factors such as nutrition, physical activity and exercise, sleep, and social engagement and connections for human healthspan and lifespan?: 01:12:01-01:16:39Dr. Morten Scheibye-Knudsen's top tip for health: 01:16:40-01:18:22

Donate (no account necessary) | Subscribe (account required) Dive into today's episode of The Wright Report as Bryan Dean Wright takes you on a global journey, starting with the latest Biden family dramas unfolding in the media. Discover Hunter Biden's legal battle against Fox News, aiming to address alleged revenge porn violations and misinformation. Meanwhile, President Joe Biden collaborates with Mexico's President to tackle illegal migration, but with a nuanced focus on non-Mexican migrants. Transitioning from the Americas, we head to Mexico for an update on the ongoing cartel wars, which might soon impact your avocado and berry prices. In Asia, we cover the political winds shifting in the Solomon Islands against China and a severe heat wave affecting the region. Back in Europe, delve into Germany's struggle with 'Dirty Green Energy' and the rise of radical Islam. On the domestic front, there's promising news for the golden years: new research suggests ways to maintain brain function as you age. Lastly, get a sneak peek at the exorbitant costs associated with building a pier off the Gaza Strip, which has escalated far beyond initial projections. Stay tuned as we connect the dots between these global events and what they mean for you.

Coleen T. Murphy, Ph.D is Director, Lewis-Sigler Institute for Integrative Genomics,  James A. Elkins, Jr. Professor in the Life Sciences, Department of Molecular Biology, and LSI Genomics, Princeton University. She is also Director, Paul F. Glenn Center for Aging Research at Princeton and Director of Simons Collaboration on Plasticity and the Aging Brain. As a researcher, Coleen studies aging and the quantitation of “quality of life with age,” including the decline of cognitive and reproductive capacities with age. She is author of How We Age: The Science of Longevity. It is surprisingly readable and understandable. Coleen has had her own lab since 2005. She finds society's obsession with nutrition and dieting limiting for her research and has, instead, questioned what else can we do to preserve our health and cognitive aging. She has won numerous awards for her research including being named a Pew Scholar. Coleen was awarded the New Innovator, Transformative R01, and two Pioneer awards from the NIH Director's office. Effective research stems from knowing the right questions to ask. Coleen MurphyConnect with Coleen:Email: ctmurphy@princeton.eduPrinceton: http://www.molbio1.princeton.edu/labs/murphy/ ORCID: 0000-0002-8257-984XBook: How We Age: The Science of Longevity(AddLink)

Aging is inevitable, but can we influence how we age? In this episode of Longevity by Design, hosts Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD,  interview Dr. Nir Barzilai—the Director of the Institute for Aging Research at the Albert Einstein College of Medicine and the Director of the Paul F. Glenn Center for the Biology of Human Aging Research and of the National Institutes of Health's (NIH) Nathan Shock Centers of Excellence in the Basic Biology of Aging—during which he discusses groundbreaking research on aging. This is an enlightening discussion with Dr. Barzilai on factors influencing healthspan and lifespan, and the paradigm-shifting idea of targeting aging to extend healthspan and lifespan. He shares fascinating insights from his research on the influence of genetics and lifestyle on healthspan and lifespan, and blood biomarkers of aging. The conversation sheds light on the emerging scientific evidence and paradigm-shifting concept for medical interventions (gerotherapeutics) to extend healthspan and lifespan by targeting the underlying biology of aging.The episode wraps up with actionable insights for listeners interested in enhancing their healthspan and longevity. Dr. Barzilai discusses the importance of personalized health strategies, integrating cutting-edge research with everyday health practices while emphasizing the importance of a holistic approach. As a listener, you will leave equipped with knowledge and science-backed ways to navigate your personal health journey and help you live healthier longer.Timestamps:Introduction: 00:00-04:13Why Dr. Barzilai's studies centenarians and their children?: 04:14-10:07 Do centenarians live longer with poor health or live healthier longer? 10:08-13:07Does becoming a centenarian have a strong genetic influence?: 13:08-15:41How do growth hormone and IGF-1 affect healthspan and lifespan?: 15:32-23:39What other genes affect healthspan and lifespan?: 23:40- 26:51Does low IGF-1 negatively impact muscle and physical functioning?: 26:52-28:40What are the effects of ethnicity and socioeconomic status on longevity: 28:41-30:57What is the effect of lifestyle, nutrition, and exercise on the longevity of centenarians?: 30:58-34:07Do women or men live longer?: 34:08-37:55Why do women live longer than men?: 37:56-41:38Biomarkers of aging and biomarkers of organ aging: 41:39-47:07What is metformin, and what is the purpose of the TAME trial?: 47:08-51:37Do you think metformin will improve healthspan and lifespan?: 51:38-54:20Does metformin only improve blood glucose control, or does it benefit health and aging in other ways? 54:21-56:50Is metformin good for older adults but not young adults?: 56:51-57:45How does the combination of metformin and exercise impact muscle size (hypertrophy) and strength?: 57:46-01:00:45Should everyone take metformin?: 01:00:46-01:03:13Dr. Gil Blander's and Dr. Nir Barzilai's personal humorous anecdotes on exercise: 01:03:14-01:04:32Is there a reason and explanation for why metformin did not show an effect on lifespan in mice in the Interventions Testing Program (ITP)?: 01:04:33-01:07:01Are GLP-1 agonists beneficial for healthspan and lifespan?: 01:07:02-01:10:55Are there tradeoffs with using GLP-1 agonists?: 01:10:56-01:11:43What are the top 5 gerotherapeutic candidates for improving healthspan and lifespan?: 01:11:44-01:15:10Dr. Nir Barzilai's top tip for improving health: 01:15:11-01:19:29

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Alex Aravanis is a leader in research and development of technologies and clinical tests utilizing the latest tools in DNA analysis and data science. In this episode, Alex delves into two interconnected topics: liquid biopsies and epigenetics. He begins by tracing the trajectory of genome sequencing and tumor sequencing, setting the stage for a detailed exploration of liquid biopsies as an early cancer detection method. The discussion encompasses key concepts such as cell-free DNA, DNA methylation, sensitivity, specificity, and the predictive values associated with liquid biopsies. Transitioning to epigenetics, Alex examines the intricate interplay of DNA methylation and aging biology and explores the possibility of using cellular reprogramming to reverse epigenetic changes that occur with aging. We discuss: Alex's background in applying engineering to problems in medicine [3:15]; A primer on human genetics, and the history and current landscape of DNA sequencing [11:00]; The advent and evolution of liquid biopsies for early detection of cancer [23:15]; The role of cell-free DNA in cancer detection: how incidental findings in non-invasive prenatal testing led to the development of liquid biopsies [40:15]; The development of a universal blood test for cancer detection and a discussion of specificity of tests [46:00]; Advancements in cell-free DNA analysis and development of a multi-cancer screening test at GRAIL [51:00]; DNA methylation explained [58:15]; Optimizing cancer detection with methylation analysis of cfDNA in small blood samples [1:02:45]; The importance of understanding sensitivity, specificity, positive predictive value, and negative predictive value in cancer screening [1:08:00]; The performance of the GRAIL Galleri test and its ability to detect various types and stages of cancer [1:21:00]; Do early cancer detection methods, like liquid biopsies, translate to improvement in overall survival? [1:27:45]; The role of epigenetics in aging [1:39:30]; How cell-free DNA methylation patterns can help identify a cancer's tissue of origin [1:45:30]; Cellular and epigenetic reprogramming and other exciting work in the field of aging [1:52:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Sleep is powerful. You've probably heard this statement a thousand times. It's all over the books, media, podcasts, videos, everywhere. But many of us still lack a deep understanding of its power and how to use it for our benefit. In today's episode, 3 guests dive deeper into understanding the amazing human mind and how sleep is critical to operating at 100% mental capacity. We talk about how to unlock its power — particularly during really hectic seasons of life.Andrew Huberman is a neuroscientist at Stanford University. He also runs the Huberman Lab, which studies how the brain functions, how it changes through experiences, and how to repair the brain after injury or disease. David Sinclair is a tenured Professor in the Department of Genetics at the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School and serves as President of the Academy for Health and Lifespan Research. He is best known for his work on understanding why we age and how to slow its effects.Dr. Matthew Walker earned his degree in neuroscience from Nottingham University, UK, and his Ph.D. in neurophysiology from the Medical Research Council in London. Dr. Walker researches the impact of sleep on human health and disease, and he's written the international bestseller, Why We Sleep, unlocking the power of sleep and dreams.In this episode you will learnHow inadequate sleep impacts brain function and overall mental health.The ideal amount of sleep necessary for optimal health and well-being.The effects of a poor diet on sleep quality, even when you're getting sufficient sleep, compared to the impact of a good diet on nights of poor sleep.Ways to influence and potentially control the nature of your dreams.Techniques to train your brain for more frequent lucid dreaming experiences.For more information go to www.lewishowes.com/1545For more Greatness text PODCAST to +1 (614) 350-3960Listen to the full episodes here:Andrew Huberman – https://link.chtbl.com/1219-podDavid Sinclair – https://link.chtbl.com/1004-guestMatthew Walker – https://link.chtbl.com/1476-pod

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Richard Miller is a professor of pathology and the Director of the Center for Aging Research at the University of Michigan, as well as a previous guest on The Drive. In this episode, Rich provides an update on the exciting work of the Interventions Testing Program (ITP), an initiative designed to assess potential life-extending interventions in mice. Rich covers the notable successes like rapamycin, 17⍺-estradiol, and acarbose as well as notable failures like nicotinamide riboside, metformin, and resveratrol, providing valuable lessons about the intricacies of the aging process. Rich delves deep into aging biomarkers and aging rate indicators, unraveling crucial insights into the science of geroprotective molecules. Additionally, Rich discusses some surprising successes of recent molecules tested by the ITP and concludes with an optimistic look at future frontiers, including bridging the gap from mice to humans. We discuss: An overview of the Interventions Testing Program (ITP) [3:45]; How the mice used by the ITP are superior for research relative to mouse models used in most research [11:15]; Design of ITP studies, outcomes tested, and metrics of interest [19:00]; The process and challenges of drug formulation for mice [30:00]; Four drugs identified by the ITP that extends the lifespan of mice [36:30]; The success of rapamycin and what it tells us about the biology of aging [43:15]; Other measures of healthspan evaluated by the ITP in stage 2 studies [50:45]; Distinguishing aging rate indicators from biomarkers of aging [57:30]; Aging rate indicators identified through the examination of slow-aging mice [59:15]; Why proteomics are essential to understand changes in the cell [1:12:15]; Unraveling aging rate indicators: dose-effect, duration, and future frontiers [1:21:45]; A closer look at aging rate indicators: bridging the gap from mice to humans [1:27:00]; What do laboratory mice die from? [1:38:45]; Distinguishing between a drug that improves an age-sensitive outcome and a drug that improves all aspects of aging [1:42:00]; The ITP study of 17⍺-estradiol: mechanisms of life extension and surprising sex differences [1:43:30]; Unsuccessful drugs studied by the ITP: resveratrol, metformin, and nicotinamide riboside [1:51:30]; Over-the-counter successes in the ITP: meclizine and astaxanthin [2:01:00]; A senolytic drug, fisetin, fails to extend lifespan [2:07:00]; Can targeting senescent cells slow aging? [2:13:00]; Optimism about future findings [2:16:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Caloric restriction. Blood transfusions. Hormetic stress. Off-label meds. As CNN's Chief Medical Correspondent, Dr. Sanjay Gupta is often asked about the latest “hacks” for longevity that pop up in the news. But do any of these interventions actually work? Can aging actually be stopped, much less reversed? In this episode, Sanjay speaks with Dr. Nir Barzilai, the director of the Institute for Aging Research at the Albert Einstein College of Medicine. He believes one of the keys to battling aging lies in our cells and genetic makeup. Plus, we hear from self-professed “biohackers,” who have some tips we can all try to extend our healthy years.To learn more about how CNN protects listener privacy, visit cnn.com/privacy