Study of the social, psychological and biological aspects of aging
POPULARITY
Andrew Humberman BioSnap a weekly updated Biography.Andrew Huberman has dominated headlines and podcast feeds this week following a series of high-impact releases and digital appearances. On October 27 his Huberman Lab podcast produced a widely discussed solo episode—Improve Your Lymphatic System for Overall Health & Appearance—where he explained the science behind the lymphatic and glymphatic systems and shared actionable protocols for reducing swelling, clearing brain fog, and supporting longevity. His emphasis on simple, cost-free methods like sleeping on one's side, breathing techniques, and intentional movement received praise across wellness communities and prompted a surge in viewer engagement, with the episode quickly trending on YouTube and generating positive feedback from certified lymphatic therapists who celebrated Huberman's evidence-based approach as seen on user responses under the same video.Moving ahead to the October 30 Essentials edition, Huberman welcomed Dr. David Sinclair from Harvard Medical School to discuss cutting-edge findings in aging and longevity. Major headlines focused on their dialogue about fasting, NAD supplementation, and gene expression tools to slow or potentially reverse age-related decline. Sinclair's appearance raised the biographical stakes for Huberman, further cementing his podcast as a preferred platform for heavyweight researchers.Besides these podcast milestones, Huberman's social channels—Instagram, YouTube, and Twitter—continue to amplify daily neuroscience tips, including his viral two-step morning energy hack spotlighted by Men's Journal. His following has grown substantially, with over 800,000 newsletter subscribers now receiving his practical blueprints for health optimization.Public appearances included a feature session at the Upright Summit on October 28, where Huberman spoke to an audience of fellow scientists and high-profile wellness advocates; clips from the event quickly circulated across Twitter and YouTube, sparking fresh debate on neuroscience-led lifestyle protocols.On the business front, sponsorship deals around his podcast have remained robust. Collaborations with brands like AG1, Eight Sleep, and LMNT showcased his commercial appeal and influence in the biohacking niche, making his partnership roster even more star-studded. PodcastNotes and several roundup platforms recapped and amplified his key recent insights on dopamine control, aging, and nutrition.No major controversies or speculative reports have surfaced this week. Instead, the buzz is solidly positive: mainstream outlets like ABC World News Tonight and NEJM This Week referenced his podcast, reflecting the growing medical establishment's interest in his research communication.In summary, Andrew Huberman's past few days have been defined by authoritative podcast releases both solo and with leaders in aging science, record social media growth, pivotal live appearances, and expanding ties to industry sponsors. His impact and biographical significance continue to accelerate as practitioners, researchers, and the public increasingly turn to him for actionable neuroscience.Get the best deals https://amzn.to/3ODvOtaThis content was created in partnership and with the help of Artificial Intelligence AI
From childhood curiosity and early passions to her son's life-changing diagnosis, Liz shares the deeply personal journey that turned her into one of the most daring figures in longevity science — even becoming the first human to test her own gene therapy.Together, Len and Liz dive into:The truth about telomeres, stem cells, and the hallmarks of agingHow AAV gene therapy could rewrite the human lifespanThe clash between innovation, regulation, and Big PharmaWhy mental health, music, and creativity are essential to longevityAnd what the future of aging gracefully — or not at all — might look likeBy the end, you'll be questioning what it really means to live a long life… and whether immortality is closer than we think. EndoDNA: Where Genetic Science Meets Actionable Patient CareEndoDNA bridges the gap between complex genomics and patient wellness. Our patented DNA analysis platforms and AI technology provide genetic insights that support and enhance your clinical expertise.Click here to check out to take control over your Personal Health & Wellness Connect with EndoDNA on SOCIAL: IG | X | YOUTUBE | FBConnect with host, Len May, on IG Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Targeting the biology of aging offers a path to stronger resilience and longer health. John C. Newman, M.D., Ph.D., explains that aging arises from measurable cellular processes, often called hallmarks of aging, including changes involving mitochondria, stem cells, cellular senescence, inflammation, and protein quality control. Newman describes how basic science in model organisms reveals mechanisms that can be manipulated to extend healthy lifespan and guide therapies. Emerging approaches aim either to strengthen stress responses that make cells more resilient or to address downstream consequences. Many clinical studies across the country now test interventions that target aging, supported by national efforts to standardize methods and expand training. Newman also investigates ketone bodies as energy sources that influence inflammation, muscle preservation, and other processes relevant to frailty and recovery. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40961]
Targeting the biology of aging offers a path to stronger resilience and longer health. John C. Newman, M.D., Ph.D., explains that aging arises from measurable cellular processes, often called hallmarks of aging, including changes involving mitochondria, stem cells, cellular senescence, inflammation, and protein quality control. Newman describes how basic science in model organisms reveals mechanisms that can be manipulated to extend healthy lifespan and guide therapies. Emerging approaches aim either to strengthen stress responses that make cells more resilient or to address downstream consequences. Many clinical studies across the country now test interventions that target aging, supported by national efforts to standardize methods and expand training. Newman also investigates ketone bodies as energy sources that influence inflammation, muscle preservation, and other processes relevant to frailty and recovery. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40961]
Targeting the biology of aging offers a path to stronger resilience and longer health. John C. Newman, M.D., Ph.D., explains that aging arises from measurable cellular processes, often called hallmarks of aging, including changes involving mitochondria, stem cells, cellular senescence, inflammation, and protein quality control. Newman describes how basic science in model organisms reveals mechanisms that can be manipulated to extend healthy lifespan and guide therapies. Emerging approaches aim either to strengthen stress responses that make cells more resilient or to address downstream consequences. Many clinical studies across the country now test interventions that target aging, supported by national efforts to standardize methods and expand training. Newman also investigates ketone bodies as energy sources that influence inflammation, muscle preservation, and other processes relevant to frailty and recovery. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40961]
Targeting the biology of aging offers a path to stronger resilience and longer health. John C. Newman, M.D., Ph.D., explains that aging arises from measurable cellular processes, often called hallmarks of aging, including changes involving mitochondria, stem cells, cellular senescence, inflammation, and protein quality control. Newman describes how basic science in model organisms reveals mechanisms that can be manipulated to extend healthy lifespan and guide therapies. Emerging approaches aim either to strengthen stress responses that make cells more resilient or to address downstream consequences. Many clinical studies across the country now test interventions that target aging, supported by national efforts to standardize methods and expand training. Newman also investigates ketone bodies as energy sources that influence inflammation, muscle preservation, and other processes relevant to frailty and recovery. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40961]
Targeting the biology of aging offers a path to stronger resilience and longer health. John C. Newman, M.D., Ph.D., explains that aging arises from measurable cellular processes, often called hallmarks of aging, including changes involving mitochondria, stem cells, cellular senescence, inflammation, and protein quality control. Newman describes how basic science in model organisms reveals mechanisms that can be manipulated to extend healthy lifespan and guide therapies. Emerging approaches aim either to strengthen stress responses that make cells more resilient or to address downstream consequences. Many clinical studies across the country now test interventions that target aging, supported by national efforts to standardize methods and expand training. Newman also investigates ketone bodies as energy sources that influence inflammation, muscle preservation, and other processes relevant to frailty and recovery. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40961]
Andrew Russell, associate professor of biology at Hillsdale College, joins host Scot Bertram to discuss developing research in anti-aging methods, the importance of diet and exercise, and the ethics of extended lifespans. Learn more: https://k12.hillsdale.edu/See omnystudio.com/listener for privacy information.
BUFFALO, NY — October 3, 2025 — A new #research perspective was #published in Volume 17, Issue 9 of Aging-US on August 26, 2025, titled “Analysis of the current state of frailty indexes and their implementation for aging intervention studies.” In this work, led by first author Oliver G. Frost from Loughborough University alongside corresponding authors Abdelhadi Rebbaa and Amit Sharma, from the Lifespan Research Institute, the authors explore growing concerns about the lack of standardization in how frailty is measured in rodent aging studies, which may limit the development of effective interventions targeting age-related decline. Frailty, a key indicator of deteriorating health in older adults, is increasingly assessed in preclinical models using frailty indexes (FIs). These indexes quantify health deficits, such as reduced mobility, cognitive decline, or physical weakness. However, this perspective highlights that FI methodologies vary significantly across studies, from the selection of parameters to the cut-off thresholds used, resulting in inconsistent outcomes that affects reproducibility and translational value. The authors reviewed 18 rodent studies and found substantial variation in how frailty is defined and measured. Some FIs rely on clinical observations, such as appearance or beahaviour, while others focus on physical performance metrics like grip strength or locomotion. In several cases, applying different FIs to the same group of animals produced contradictory results, underscoring the importance of harmonized protocols. To illustrate these issues, the researchers applied an 8-item FI to mice of different ages and found that even young mice were sometimes scored as frail, depending on the scoring method and reference values. This finding emphasizes the need for consistent baselines and controlled environments, especially when comparing across studies. The authors recommend using each animal as its own baseline in longitudinal studies, a strategy that enhances reliability without adding significant cost. “Sex as a biological variable in FIs is an important consideration, as there is a known difference between male and female frailty onset and progression.” The authors also discuss emerging automated tools, such as video-based open-field testing, which can reduce observer bias and improve reproducibility. In the future, broader health indicators, such as cognition, circadian rhythms, social behavior, and body composition, may further enhance frailty assessments. Overall, this work underscores the urgent need for standardized, transparent, and reproducible methods for evaluating frailty in preclinical aging studies. Improved consistency in frailty scoring will better inform the development of healthspan-extending therapies and enhance the translational relevance of animal models. DOI - https://doi.org/10.18632/aging.206307 Corresponding authors - Abdelhadi Rebbaa - rebbaa@gmail.com, and Amit Sharma - amit.sharma@sens.org Abstract video - https://www.youtube.com/watch?v=eha3XA9LyWA Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206307 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, frailty, rodents, frailty index, phenotype To learn more about the journal, please visit our website at https://www.Aging-US.com and connect with us on social media at: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
Send us a textWhat if one of the most powerful tools for slowing biological aging has been hiding in plain sight for decades?This week on The Daily Apple, Dr. Brad Younggren joins us to unpack therapeutic plasma exchange (TPE) and why it could be a game-changer for longevity. Dr. Younggren is an emergency medicine physician, U.S. Army combat veteran, and now CEO and co-founder of Circulate Health. Under his leadership, Circulate has completed more than a thousand treatments across 24 clinics and published data showing an average 2.6-year slowdown in biological aging.“Therapeutic plasma exchange isn't just for rare hospital cases anymore. We're learning it can lower inflammation, clear out harmful proteins, and even reduce microplastics — all things tied to how fast we age.” — Dr. Brad YounggrenWe talk about:What TPE actually is (and how it differs from a blood donation).Results from the Circulate Trial and why they matter.How plasma exchange impacts inflammation, senescent cells, and lipids.Early research on microplastics and cognitive decline.Why partnerships with clinics may be the fastest path to making longevity care more accessible.Dr. Younggren also shares his own journey from combat medicine to pioneering new frontiers in healthspan, and where he sees longevity breakthroughs heading in the next decade.
As the global population grows older, understanding what drives the aging process is becoming increasingly important. Diseases like Alzheimer's, cardiovascular conditions, and cancer are more common with age, yet many current treatments only manage symptoms rather than addressing the underlying biological causes. One contributor to aging is the buildup of “senescent” cells—cells that have stopped dividing but do not die. These cells can harm nearby tissues by releasing molecular signals, a process known as secondary senescence. Scientists have found that senescent cells release tiny particles called exosomes. A research team from The Buck Institute for Research on Aging recently discovered that these exosomes carry aging-related messages through the bloodstream. Their study, titled “Exosomes released from senescent cells and circulatory exosomes isolated from human plasma reveal aging-associated proteomic and lipid signatures,” was featured as the cover article in Aging (Aging-US), Volume 17, Issue 8. Full blog - https://aging-us.org/2025/09/how-exosomes-spread-aging-signals-and-could-support-anti-aging-research/ Paper DOI - https://doi.org/10.18632/aging.206292 Corresponding author - Birgit Schilling - bschilling@buckinstitute.org Video short - https://www.youtube.com/watch?v=tcyAZahw-g8 Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206292 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, proteomics, senescence, exosomes, data-independent acquisitions To learn more about the journal, please visit our website at https://www.Aging-US.com and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
In this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Eric Verdin, President and CEO of the Buck Institute for Research on Aging. Eric discusses the science behind therapeutic plasma exchange (TPE) and its potential to slow biological aging in humans. The conversation explores findings from a recent clinical trial, including measurable age reversal using epigenetic clocks.Eric explains how removing and replacing plasma can dilute pro-aging factors in the blood, a concept inspired by earlier animal studies on parabiosis. He also describes why rigorous, placebo-controlled human trials are crucial for validating longevity interventions and distinguishing the field from hype-driven wellness trends.The episode also highlights how omics data, such as metabolomics and proteomics, are shaping a new era of precision aging research. Eric emphasizes the value of lifestyle interventions as a foundation and sees future opportunities in combining TPE with personalized strategies to extend healthspan. Guest-at-a-Glance
Send us a textWe all know movement is good for us. But can the right kind of exercise actually slow the aging process itself?In this episode, Dr. Kevin White talks with Benjamin Miller, Ph.D., professor of aging research at OMRF and past president of the American Aging Association, about what really happens to our muscles and mitochondria as we age, and how his new NIH-funded clinical trial is working to answer one of the most important questions in longevity science: why do some people respond to exercise better than others?"Every drug we study is just trying to be as good as exercise — and exercise still wins."Dr. Miller explains the biology of aging in plain language, from protein damage to energy production, and shares why exercise still outperforms any “miracle drug” on the market. He also unpacks the design of his new trial, where people 60 and older will receive supervised training, advanced health testing, and wearables to measure everything from VO₂ max to sleep — all with the goal of predicting who benefits most from which type of exercise.In this episode:Why exercise is still the closest thing we have to a longevity drugHow mitochondria and protein health drive resilience as we ageWhat VO₂ max actually measures — and why it predicts lifespanThe role of genetics vs. lifestyle in how our bodies respond to trainingHow to get involved in Dr. Miller's NIH-backed exercise study at OMRFThis conversation is a reminder that slowing aging isn't about hacks or shortcuts — it's about moving, staying engaged, and using science to make every decade stronger than the last. Prime Health Associates
It was a pleasure to sit down with Dr. Nir Barzilai for a conversation that turned out to be both lively and thought-provoking. His decades of research on centenarians, biological age, and the hallmarks of aging have shaped how we think about longevity—and what's possible when we start targeting aging itself, not just individual diseases. We get into the science behind why some people live 20–30 years longer and healthier, and what it means to measure the biological age of individual organs. But we also hit a few sparks—especially when it comes to nutraceuticals and the role of metformin in prevention. I don't agree with everything you'll hear, and I followed up with Dr. Barzilai afterward to unpack some of the more provocative claims. We may just need a second round for this one... stay tuned. Check out the show notes at www.drkarafitzgerald.com/fxmed-podcast/ for all the relevant links and resources. ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources. GUEST DETAILS Nir Barzilai M.D. Director of the Einstein Institute for Aging Research Professor of Medicine and Genetics President of the Academy for Health & Lifespan Research Website: https://einsteinmed.edu/faculty/484/nir-barzilai Email: nir.barzilai@einsteinmed.edu Dr. Nir Barzilai is a pioneer in aging science, known for his work on centenarians, the biology of aging, and the TAME trial. He is Director of the Institute for Aging Research at Albert Einstein College of Medicine and author of Age Later and has published over 330 papers. THANKS TO OUR SPONSORS DIAMOND DUTCH: https://dutchtest.com/for-providers Biotics Research: https://www.bioticsresearch.com/ GOLD Vibrant Wellness: https://www.vibrant-wellness.com/ OneSkin: http://oneskin.co/DRKARA EXCLUSIVE OFFERS FROM OUR SPONSORS Why MitoQ's mitochondria-targeting is a critical step for your healthspan and longevity strategy.https://tinyurl.com/4f8t7jt6 OneSkin: Get 15% off OneSkin with the code DRKARA at oneskin.co/DRKARA CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: https://www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw
BUFFALO, NY — August 11, 2025 — Aging (Aging-US) is proud to support a milestone event for the global senescence and aging research community. This coming September 16-19, 2025, Rome, Italy will host two back-to-back events that will define the next chapter of senescence science and translation: -10th Annual International Cell Senescence Association (ICSA) Conference -Senotherapeutics Summit – organized with the Phaedon Institute This combined program could not come at a more important time. The field is entering a transformative phase: -Multiple clinical trials on senolytics and senomorphics are now reporting results, offering the first real-world evidence of their therapeutic potential. -Exciting new discoveries in senescence mechanisms, biomarkers, and tissue-specific roles are reshaping our understanding of when and how to target these cells. For the first time, the leading fundamental science meeting on cellular senescence will be directly connected with a global summit dedicated to the clinical and commercial development of senotherapeutics. This unique integration will allow participants to seamlessly move from bench to bedside discussions, exploring both the latest research and its translation into therapies that could transform how we approach aging and age-related diseases. Highlights include: -Keynotes from pioneers driving both discovery science and translational innovation -Sessions on mechanisms, biomarkers, and emerging targets -Industry and regulatory panels on clinical trial design, safety, and approval pathways -Case studies from ongoing and completed human trials -Networking with leaders from academia, biotech and pharma Celebrate a decade of ICSA and help chart the path for the next generation of senescence science and therapeutics. Registration is still open: https://icsa2025rome.com/ To learn more about the journal, please visit our website at https://www.Aging-US.com and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM
Unveiling the Gut-Brain Connection: Dr. Steven Gundry on Leaky Gut, Microbiome, and Health In today's episode, we dive deep into the fascinating world of the gut-brain connection with Dr. Steven Gundry, a prolific author and expert on the subject. Starting with a brief introduction about our sponsor, Kyndryl, we explore the historical context of medical insights from figures like Hippocrates and Ignaz Semmelweis. Dr. Gundry shares compelling stories from his practice, including miraculous patient turnarounds attributed to gut health. We discuss the latest in microbiome research, the concept of leaky gut, and how our gut's terrain influences overall health. Learn about the critical role of bacteria in our body's ecosystem, the intelligence of microorganisms, and their impact on our well-being. Join us as we unlock the secrets of a balanced inner terrain and its implications for a healthier life. 00:00 Introduction and Sponsor Message 00:30 Dedications and Historical Insights 02:06 Guest Introduction: Stephen Gundry 03:04 Remarkable Patient Stories 07:19 The Gut-Brain Connection 12:52 Historical Debate: Pasteur vs. Bechamp 16:58 Microbiome Discoveries and Implications 19:08 Bacterial Intelligence and Communication 26:29 Elephant Communication and Eavesdropping 27:04 Understanding Leaky Gut 27:52 Aging Research and Sea Elegans 29:45 The Role of Tight Junctions in Gut Health 32:46 Impact of Diet and Antibiotics on Gut Health 36:44 Environmental Toxins and Autoimmune Diseases 37:40 Lipopolysaccharides and Immune Response 42:03 The Rise of Food Sensitivities and Allergies 47:05 Gut Microbiome and Food Cravings 48:10 Conclusion and Resources Find Steven: https://drgundry.com
Send us a textDr. On-Yee (Amy) Lo, Ph.D. is Assistant Scientist II at the Marcus Institute for Aging Research ( https://www.marcusinstituteforaging.org/who-we-are/profiles/yee-amy-lo-phd ) and Assistant Professor of Medicine, Harvard Medical School and Beth Israel Deaconess Medical Center ( https://connects.catalyst.harvard.edu/Profiles/display/Person/147630 ).Dr. Lo is a physical therapist and research scientist who aims to prevent functional decline and enhance functional independence for older adults with mobility impairments by conducting experimental and translational research. She has expertise and experience in physical therapy, biomechanics, neuroimaging, and neuromodulation.Dr. Lo has dedicated her career to enhancing functional independence and quality of life in older adults. Her specific research objectives are: - To investigate connections between the brain and body that enable safe navigation throughout daily environments.- To innovate rehabilitative interventions that target these brain and body connections to preserve and restore the control of mobility.- To implement the experimental findings into the clinical setting.Dr. Lo's clinical and scientific training in physical therapy, biomechanics, neurophysiology, neuroimaging, neuromodulation, and gerontology have enabled her to cultivate her passions in conducting translational research to help older adults walk and move safely in real life. She incorporates cognitive, brain, and movement sciences to understand the complex control of gait and mobility, and develop individualized, multi-modal, and patient-centered interventions that can both stand alone and be combined with current evidence-based geriatric rehabilitation programming to improve mobility and mitigate fall risks in older adults. Dr. Lo has a Master of Arts (M.A.) in Pathokinesiology from New York University and a Doctor of Philosophy (Ph.D.), Human Physiology from University of Oregon.#PhysicalTherapy #Biomechanics #Neurophysiology #Neuroimaging #Neuromodulation #Gerontology #TranscranialDirectCurrentStimulation #Gait #Mobility #GeriatricRehabilitation #Cognition #Pathokinesiology #HumanPhysiology #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #Podcasting #ViralPodcast #STEM #Innovation #Science #Technology #ResearchSupport the show
Dr. Laura welcomes Kirkland Shave, co-founder of the Mountain Trek health reset retreat, and Dr. Kelly Tremblay, neuroscientist and certified coach, to Where Work Meets Life™to explore the connection between holistic health, burnout prevention, and the mind-body connection. Kelly and Kirk discuss the prevalence of stress and burnout in today's society and our lack of meaningful connection to nature and our own bodies and minds. Dr. Laura investigates these issues from a neurological perspective and a practical wellness approach with both Kelly and Kirk, learning what can be done to reset our healing.Forest bathing, flow trekking and sensory health practices that involve engaging with sound, scent, and visual natural experiences are all part of the conversation. Connecting with our senses and the reality of nature while separating ourselves from screens and demands can dramatically reduce stress and enhance brain function. While Kelly shares neuroscience research linking stress to actual structural brain changes, Kirk offers transformative stories from Mountain Trek, where guests can unplug from digital overload. Dr. Laura highlights the importance of understanding the causes of our burnout and how we can take control to heal our body and mind.“You've probably heard about it's Shinrin-yoku, a Japanese-researched way of being moment to moment, mindful of the sensorial information that's coming through our sense organs into the brain. And you're doing that in nature, and you're in a state of flow… where you're not thinking about other things. You're paying attention to what do I see? Or what do I see in motion in front of me? Or what do I hear out of this ear versus this ear? Or what do I smell as I go by the bark of this tree? Or which direction is the sun landing on my skin? These moment-to-moment awarenesses have been proven to lower the stress hormone cortisol. The Japanese researched this, and the main reason why they did this research is because in the 80s, as the tech industry took off in Japan, people were working 12-hour days already that we're working now, and the work burnout was through the roof.” - Kirkland ShaveAbout Kirkland Shave:Kirkland Shave, founder and president of the world-renowned Mountain Trek program, now offers off-site interactive and eye-opening workshops — grounded in anthropological health science — to help professionals integrate lasting steps in reaching optimal wellness. With an inspiring, practical, and actionable message, Kirkland helps people see their own health through a fresh and practical lens.With half- and full-day interactive health workshops and keynote presentations — designed specifically for a corporate audience — held at your company's headquarters, Kirkland's life-changing interactive presentation can be tailored to meet a number of health issues: Fitness, Nutrition, De-Stressing, Sleep Hygiene, Physical and Digital Detoxification, Habit Formation, Mindfulness.His proven approach increases energy, productivity, and establishes long-lasting health habits. The program incorporates scientific anthropology blended with a distinctly mountain-centric approach to health. With 18 years' experience as president and founder of Mountain Trek's holistic health and vitality program, Kirkland brings more than 40 years of health-focused lifestyle expertise, with experience as a fitness instructor, lead hiking guide, wellness coach, Wilderness Park Manager, yoga instructor and meditation practitioner.Kirkland's off-site workshops for executives and employees have been hosted by leading organizations, such as Google, Young Presidents Organization of Western Canada, Fortis Gas, the CEO Network, European Entrepreneurs Organization, and more. Contact Kirkland Shave and Mountain Trek:Website: MountainTrek.com https://mountaintrek.com/Instagram: @mountaintrek https://www.instagram.com/mountaintrek/Facebook: @mountaintrek https://www.facebook.com/mountaintrekInstagram: @mountaintrek https://www.instagram.com/mountaintrekLinkedIn: Mountain-Trek https://www.linkedin.com/company/mountain-trek/YouTube: YouTube.com/MountainTrek https://www.youtube.com/mountaintrekKirkland Shave on LinkedIn: https://www.linkedin.com/in/kirkland-shave-66865b29/TripAdvisor: https://www.tripadvisor.com/Hotel_Review-g499116-d223075-Reviews-Mountain_Trek_Fitness_Retreat_Health_Spa-Ainsworth_Hot_Springs_Kootenay_Rockies_British.htmlAbout Dr. Kelly Tremblay, MSc PhD CEC-ACC:Dr. Trembly is committed to making aging better by innovating in the areas of health, tech, and education through leadership, research, and advocacy.She is a consultant, neuroscientist and clinical audiologist who has worked in healthcare, tech, and higher education for 25+ years. As a tenured professor, Dr. Tremblay's NIH-funded research shed light on how we can capitalize on the brain's plasticity to promote perceptual and behavior changes well into our later years. Her work in the areas of communication neuroscience, person-centred care, and digital health technology has been recognized with invitations to serve on many committees at the National Institutes of Health, the American Federation for Aging Research's National Scientific Advisory Council, Mitacs Canada, and the World Health Organization. She leads advocacy initiatives and serves on many boards, including the Hearing Loss Association of America, where she was a Board Trustee and Co-Founder and Chair of the Task Force for Accessible, Inclusive Employment.Because work and health are social determinants of quality of life and healthy aging, Dr. Tremblay also works with leaders in all sectors, as an ICF-certified executive coach, to promote healthy, accessible, multi-generational workplaces where people can flourish. She's certified by the International Coaching Federation and a Fellow of the McLean Institute of Coaching (an affiliate of Harvard Medical School), who loves helping people rewire and inspire!Contact Dr. Kelly Tremblay: Website: DrKellyTremblay.com https://drkellytremblay.com/LinkedIn: Dr-Kelly_Tremblay https://www.linkedin.com/in/dr-kelly-tremblay Resources:Website: MountainTrek.com“Nature and human well-being: The olfactory pathway” Science Advances | May 2024 | Vol 10 Issue 20Parks Canada Health and WellnessShinrin-yoku“The Myth of Normal” by Gabor Mate“When Things Fall Apart” by Pema ChödrönLearn more about Dr. Laura on her website: https://drlaura.liveFor more resources, look into Dr. Laura's organizations: Canada Career CounsellingSynthesis Psychology
Recently the Endocrine Society’s Bone and Mineral Special Interest Group discussed the importance of fracture liaison services and how they contribute to an improved quality of life for patients and cost saving for the facility. An important part of the discussion revolved around a recent perspective published in The New England Journal of Medicine titled, “Coordinating Multidisciplinary Care — Improving Outcomes after Fragility Fractures.” The article notes that despite the benefits of fracture liaison services, the lack of reimbursement for those services in the United States is a significant financial barrier, rendering the service underutilized. The article further states that the global burden of hip fractures is expected to double over the next few decades. Are we looking at an impending crisis? What role should fracture liaison services play in reducing treatment gaps and improving post-fracture care? Host Aaron Lohr talks with the three authors of that New England Journal of Medicine perspective: Nicola Napoli, MD, PhD, associate professor of endocrinology and metabolism at Campus Bio-Medico University of Rome, Italy; Peter Ebeling, AO, professor medicine at Monash University in Melbourne, Vic., Australia; and Douglas P. Kiel, MD, professor of medicine at Marcus Institute for Aging Research at Hebrew Senior Life. Show notes are available at https://www.endocrine.org/podcast/enp99 — for helpful links or to hear more podcast episodes, visit https://www.endocrine.org/podcast
ENCORE – Originally aired November 7, 2024 There's a lot of attention right now around “super agers.” Yet the facts are that current life expectancy at birth is 74.8 years for males and for females it's 80.2 years in the U.S. Does it catch your eye when you hear about predictions we'll be able to live to 100 and beyond? Some researchers are throwing cold water on those notions. “We'll be lucky if 5% of the age cohort makes it... Read More Read More The post How Realistic is Super Aging? Research-Based Answers (Encore) appeared first on Healthy Communities Online.
In this compelling episode of Research Renaissance, host Deborah Westphal sits down with Sue Peschin, President and CEO of the Alliance for Aging Research, for a candid conversation about the intersection of science, policy, and aging. From Alzheimer's drug coverage to the future of stem cell research, they unpack what it truly means to age with dignity—and how equity, access, and advocacy play a critical role.Sue shares her personal journey into aging research, her leadership transition at the Alliance, and the organization's long-standing commitment to ensuring older adults receive fair and effective healthcare. They explore the challenges of Coverage with Evidence Development (CED) in Medicare, the rising need for culturally competent communication, and how the stigma around neuropsychiatric symptoms in aging can be addressed through education and empathy.Key Topics Covered:The origins and mission of the Alliance for Aging ResearchMedicare's use of “Coverage with Evidence Development” for Alzheimer's therapiesChallenges in equitable access to aging-related treatmentsThe political and scientific landscape of stem cell researchOutreach strategies for underserved and underrepresented aging populationsNeuropsychiatric symptoms in dementia and the importance of caregiver educationMental health trends in older adults and increasing substance use concernsThe role of policy, education, and interdisciplinary collaboration in advancing healthy agingMemorable Quote: “Everybody deserves to age as healthy as they can.” – Sue PeschinResources & Links:
We are joined by physical therapists Saurabh Mehta and Christos Karagiannopoulos, who – along with a team of therapists and surgeons – developed a clinical practice guideline for rehabilitation following distal radius fractures. They share with us how a CPG is developed, how the evidence is synthesized and how they came to their conclusions based on the evidence to provide recommendations for evaluation, interventions and prognosis. Guest Bios: Dr. Karagiannopoulos is a full-time associate professor at DeSales University DPT program with a current line of research on the assessment and management of wrist sensorimotor control impairment. He has earned a Bachelor of Science, a Master of Education, and a Doctor of Philosophy in Kinesiology from Temple University. His master's in physical therapy was earned from MCP-Hahnemann University (Drexel University) in 1999. Christos has dedicated his 20+ years clinical practice in orthopedic physical therapy and the rehabilitation of the upper extremity as a Certified Hand Therapist. He has dedicated his clinical research line on the wrist sensorimotor control impairment, developing the active wrist joint position sense test and its psychometric properties. Dr. Karagiannopoulos has published his most recent research work in the Journal of Hand Therapy, and he co-authored the most recent 2024 APTA Clinical Practice Guidelines on distal radius fracture rehabilitation in the JOSPT. He has also co-authored the 2020 AAOS Clinical Practice Guidelines for distal radius fracture management. Dr. Karagiannopoulos has lectured at various local, national, and international symposiums. He currently serves on the APTA Academy of Hand & Upper Extremity as a program co-chair and a member of the research committee. He is also a member of the Journal of Hand Therapy editorial board.Dr. Mehta is a board-certified specialist in geriatric physical therapy and the Director of Research for the College of Health Sciences at East Tennessee State University. He has collaborated and published multiple data-based articles and systematic reviews in upper extremity rehabilitation, healthy aging, and improving physical functions in the elderly. Dr. Mehta recently led the efforts to develop ICF-based clinical practice guidelines for the rehabilitation of distal radius fractures. He is the chair of the Aging Research and Geriatric Rehabilitation Networking Group of the American College of Rehabilitation Medicine
Deborah Kado is a geriatrician who believes her field is misunderstood. Her interest in the science of aging began with a childhood encounter in a nursing home but recently resulted in intriguing work in which Kado linked microbes in the gut to vitamin D metabolism and poor sleep. Kado refuses to blame aging alone for health problems, advocating for better care regardless of age. It's never too late to strive for better health, Kado tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Deborah KadoConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Deborah Kado, a professor of medicine and epidemiology at Stanford University.(00:03:22) Origin Story in GeriatricsHow a childhood encounter led to Deborah's career in geriatrics.(00:06:04) Geriatrics vs. GerontologyThe clinical and research distinctions between the two related fields.(00:06:58) Rethinking AgingReframing aging as a lifelong process rather than decline and loss.(00:08:34) Patient Care ApproachWhy symptoms should be investigated, not dismissed as inevitable aging.(00:11:33) Linking Bone Health, Gut, and BrainThe surprising relationship between microbiomes, bones, and cognition.(00:14:34) Vitamin D: Storage vs. Active FormWhy only the active form of vitamin D correlates with microbiome health.(00:17:22) Gut Health and SleepHow better sleep quality is linked to healthier microbiomes.(00:21:20) Medical Education & Geriatric TrainingThe shortage of geriatrics training in U.S. medical schools.(00:23:08) Measuring Geriatric KnowledgeThe challenges and efforts to measure student knowledge about aging.(00:27:24) Takeaways for Medical ProfessionalsTwo anecdotes where symptoms were misattributed to old age.(00:30:51) Empowering Aging PatientsAdvice to aging individuals: agency, purpose, and not settling for less care.(00:34:02) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook
Send us a textIn this episode of Causes or Cures, Dr. Eeks chats with aging and longevity expert Dr. Heike Bischoff-Ferrari about whether simple lifestyle interventions, like supplementation and exercise, can actually make us biologically younger.Dr. Bischoff-Ferrari breaks down: • What DNA methylation clocks are and how they're used to measure biological age • The design and findings of the DO-HEALTH Bio-Age Trial • Whether vitamin D, algae-based omega-3s, and exercise can turn back your biological clock • The science behind how these interventions may work • Practical takeaways for longevity and healthy aging • What's next in this fast-moving fieldDr. Bischoff-Ferrari is a physician and researcher with board certifications in geriatrics, internal medicine, and rehab. She's a professor at the University of Zurich where she chairs the Department of Geriatrics and Aging Research, and the principal investigator of DO-HEALTH, Europe's largest study ever on healthy longevity. With a doctorate from Harvard and a long-standing commitment to aging research, she's at the forefront of understanding how to extend not just lifespan, but healthspan. You can learn more about her here. You can contact Dr. Eeks at bloomingwellness.com.Follow Eeks on Instagram here.Or Facebook here.Or X.On Youtube.Or TikTok.SUBSCRIBE to her monthly newsletter here.Support the show
WPRB News and Culture: The Pidgin has growing pains, and we can feel ourselves aging like fine wine, so today we're talking seniority – in all the meanings of the word. We talk about the elders in our lives, and our communities, but we're also thinking about chapters ending and beginning. Ariel Chen starts us off by reporting on this past week's May Day protests in the community, and points to how older people are starting to become the new face of activism. For our culture segment, Margo Mattes reflects on personal stories from the drama of her grandmother's nursing home, and reflects on how the way we feel, and interact with other people, never really changes as we move through life. Finally, for our science segment, Teo Grosu and Natalia Maidique talk to Dr. Coleen Murphy, a researcher at Princeton who studies aging in many forms, about how research often needs the space to grow and age for its true importance to be revealed.Hosted and produced by Teo Grosu and Natalia Maidique. Reported, recorded, and produced by Ariel Chen, Margo Mattes, Teo Grosu, and Natalia Maidique.All music used under Creative Commons license.(00:00) Introduction(01:35) May Day Protests(15:03) Acting Your Age(24:50) Aging Research
Send us a textIn this episode of Causes or Cures, Dr. Eeks chats with Dr. Amir Baniassadi about how indoor temperature affects the aging brain.Dr. Baniassadi shares what we know so far about the relationship between temperature and cognitive function, and explores the theories behind how temperature might influence cognition as we age. He discusses the findings of his recent study on temperature and cognition, including what surprised his team most. He also touches on an earlier study he conducted on temperature and sleep, and offers practical tips for optimizing your home environment. Is there a “sweet spot” for room temperature that supports both clear thinking and better sleep?Dr. Baniassadi is an instructor of medicine at Harvard Medical School and a scientist at the Marcus Institute for Aging Research. His work focuses on the aging brain and how environmental factors affect health and well-being in older adults. He holds a PhD in Civil, Environmental, and Sustainable Engineering from Arizona State University and an undergraduate degree in Mechanical Engineering from the University of Tehran. He also completed postdoctoral training in Translational Research in Older Adults, as well as a fellowship at the Harvard Graduate School of Design.Learn more about his work here. You can contact Dr. Eeks at bloomingwellness.com.Follow Eeks on Instagram here.Or Facebook here.Or X.On Youtube.Or TikTok.SUBSCRIBE to her monthly newsletter here.Support the show
Aging Research in Women takes center stage as Dr. Jennifer Garrison uncovers the overlooked reality that ovaries age faster than any other organ. This rapid aging, occurring at a rate two and a half times quicker than other tissues, significantly impacts women's health spans. From heightened cardiovascular risks to osteoporosis, the consequences of accelerated ovarian aging are vast, especially post-menopause. Yet, ovarian health research has long suffered from severe underfunding. At the Buck Institute for Research on Aging, Garrison's work aims to address this deficit by understanding the brain-ovary signaling axis, which she believes is key to promoting healthier aging for women. Sponsored by Qualia Senolytic: https://qualialife.com/podcastoffer. Use code podcast when you shop Qualia Senolytic for 15% off your order. Get in touch. Instagram: https://www.instagram.com/qualialife. Facebook: https://www.facebook.com/qualialife. Email: support@qualialife.com.
This episode is brought to you by Bon Charge and Momentous. We used to think circadian rhythm only applied to sleep. But emerging science has revealed a link between our circadian rhythm and metabolism, cognition, risk for chronic diseases, and many other crucial aspects of our health. Our biology was designed to live in sync with a natural light-dark cycle, but modern-day society has disrupted this natural balance. Today on The Dhru Purohit Show, we're revisiting one of our favorite episodes with Dr. Satchin Panda. Dr. Panda dives deep into his groundbreaking circadian biology research and shares how leveraging your circadian rhythm can dramatically improve your sleep, lower your risk of chronic disease, and improve your cognitive function. They also discuss how time-restricted eating, exercise, and light can be used to help program your circadian rhythm and why it's especially important for shift workers to take advantage of these tools. Dr. Panda is pioneering circadian biology research. He is a professor at the Salk Institute for Biological Studies, a Pew Biomedical Scholar, founder of the UC San Diego Center for Circadian Biology, and recipient of the Julie Martin Mid-Career Award in Aging Research. Dr. Panda has spoken at conferences around the world about his work on circadian rhythms and diabetes, including Diabetes UK, the American Diabetes Association, the Danish Diabetes Association, and the professional diabetes societies of Europe and Australia. In this episode, Dhru and Dr. Panda dive into: Why late-night eating is so detrimental to our health (2:15) Organ systems that have a circadian rhythm (8:24) Common ailments that could be related to circadian rhythm disturbances (14:11) Night-shift work and cancer risk (20:19) How poor sleep perpetuates bad food choices (27:00) What happens in the body when you rely on an alarm clock (44:01) Why you need to accumulate sleep debt for better sleep (51:25) Time-restricted eating and sleep (1:00:40) How to combat fragmented sleep (1:15:35) The best time to work out (1:55:50) The link between exercise and cancer (2:07:55) Positive changes for better sleep health on a global scale (2:17:20) Strategies for night-shift workers to combat circadian rhythm disruption 02:45:10) Dr. Panda's research in firefighters (2:48:46) Tips for optimizing your circadian rhythm (3:14:20) Where to follow and support Dr. Panda's work (3:27:50) Also mentioned in this episode: The Circadian Code: Lose Weight, Supercharge Your Energy, and Transform Your Health from Morning to Midnight The Circadian Diabetes Code: Discover the Right Time to Eat, Sleep, and Exercise to Prevent and Reverse Prediabetes and Diabetes Download the MyCircadianClock app Try This: 6 Crazy Facts About Sleep Try This: How Exercise Helps Fight Cancer For more on Dr. Satchin Panda, follow him on Twitter @SatchinPanda, Instagram @satchin.panda, or his Website. This episode is brought to you by Bon Charge and Momentous. Right now, BON CHARGE is offering my community 15% off; just go to boncharge.com/DHRU and use coupon code DHRU to save 15%. Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Go to livemomentous.com and enter promo code DHRU to get 20% off any order. Learn more about your ad choices. Visit megaphone.fm/adchoices
On this episode of Longevity by Design, Dr. Gil Blander speaks with Dr. Michael Ringel, COO of Life Biosciences, about the science of aging and longevity. Michael discusses how evolution influences lifespan and why aging occurs. He explains the trade-off between resource allocation for reproduction versus maintenance and repair within the body. Caloric restriction and its effects on lifespan are explored through an evolutionary lens.Michael highlights the challenges and breakthroughs in longevity research. He touches upon the role of genetics and pharmaceuticals in manipulating lifespan and healthspan. He points to the Pacific rockfish as an example of varying lifespans within a closely related group of species, demonstrating the genetic component of aging. He also notes the impact of Cell reprogramming, referencing a study on how specific Cell reprogramming can regenerate optic nerves.The conversation shifts to the business of longevity, where Michael discusses the increased interest and investments from big pharma and billionaires. He examines the economic benefits of extending healthspan, citing a potential value of $300 trillion from a 10-year healthspan extension in the US alone. Michael and Gil also explore the importance of lifestyle choices for healthy aging, emphasizing diet, exercise, sleep, stress management, and social connections.Guest-at-a-Glance
In the Season 3 premiere of the Longevity & Aging Series, Dr. Yu-Xuan Lyu from Southern University of Science and Technology (Shenzhen, China) joins host Dr. Evgeniy Galimov to discuss his co-authored research paper, featured as the cover for Aging (Aging-US) Volume 16, Issue 20, titled “Longevity biotechnology: bridging AI, biomarkers, geroscience, and clinical applications for healthy longevity.” #aging #author #interview #series #biotechnology #ai #artificialintelligence #longevity #healthspan #lifespan #oa #openscience #peerreview #journal #publication #publishing #meded #agingshort #video DOI - https://doi.org/10.18632/aging.206135 Corresponding authors - Yu-Xuan Lyu - lvyx@sustech.edu.cn, Alex Zhavoronkov - alex@insilico.com, Morten Scheibye-Knudsen - mscheibye@sund.ku.dk, and Daniela Bakula - bakula@sund.ku.dk Video interview - https://www.youtube.com/watch?v=VUfNxWdBV5k Video short - https://www.youtube.com/watch?v=Hpfe5WJ5g7I Abstract The recent unprecedented progress in ageing research and drug discovery brings together fundamental research and clinical applications to advance the goal of promoting healthy longevity in the human population. We, from the gathering at the Aging Research and Drug Discovery Meeting in 2023, summarised the latest developments in healthspan biotechnology, with a particular emphasis on artificial intelligence (AI), biomarkers and clocks, geroscience, and clinical trials and interventions for healthy longevity. Moreover, we provide an overview of academic research and the biotech industry focused on targeting ageing as the root of age-related diseases to combat multimorbidity and extend healthspan. We propose that the integration of generative AI, cutting-edge biological technology, and longevity medicine is essential for extending the productive and healthy human lifespan. Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206135 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, biotechnology, artificial intelligence, healthy longevity About Aging-US The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM
BUFFALO, NY — February 26, 2025 — A new #research paper was #published in Aging (Aging-US) on January 27, 2025, in Volume 17, Issue 1, titled “Age-invariant genes: multi-tissue identification and characterization of murine reference genes.” Aging is a process driven by changes in gene activity, but researchers from Yale University School of Medicine and Altos Labs, led by first author John T. González and corresponding author Albert T. Higgins-Chen, have identified a set of genes that remain unchanged throughout the aging process. This discovery could improve the accuracy of aging research and provide insights into why some genes stay unchanged while others decline. “Reference genes have mostly been identified and validated in young organisms, and no systematic investigation has been done across the lifespan.” The study looked at gene activity in 17 different tissues in mice, from 1 month old to over 21 months old. Scientists used advanced bioinformatic analysis methods to analyze RNA sequencing data. They found nine genes that stayed the same across all tissues, as well as other genes that remained stable in specific tissues. These genes are usually shorter and have special DNA regions called CpG islands, which may help cells stay healthy and resist aging. Their stability throughout aging was confirmed by analyzing different datasets and using RT-qPCR. One of the most significant findings is that these stable genes are linked to essential cellular functions, such as mitochondrial activity and protein maintenance. This challenges the common belief that all aspects of aging involve gene dysregulation. Instead, the findings suggest that some cellular processes may naturally resist aging, leading the way for new research on longevity and potential anti-aging therapies. “Biological processes that change with age and those that resist age-related dysregulation are two sides of the same coin, and both will need to be investigated to fully understand aging.” Another key finding is that commonly used reference genes, such as GAPDH and ACTB, fluctuate with age, making them unreliable for aging studies. No single classical reference gene was found to be stable across all tissues. Researchers often use these reference genes as a control to measure gene activity, but if their expression changes over time, it can lead to inaccurate results. By identifying new, stable reference genes, this study provides scientists with better tools for studying aging-related diseases, regenerative medicine, and longevity science. Understanding how certain genes remain unchanged throughout life suggests that they may play a protective role in aging and could potentially be used to develop treatments that slow down age-related decline. While further research is needed, this discovery sets a new standard for measuring gene activity in aging studies and could have a significant impact on aging research and medicine. DOI - https://doi.org/10.18632/aging.206192 Corresponding author - Albert T. Higgins-Chen - a.higginschen@yale.edu About Aging-US The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM
Transcript with time code: https://cuttingedgehealth.com/wp-content/uploads/2025/02/Transcript-47-Dr-Venki-Ramakrishnan.pdf In this episode, Jane interviews Nobel Prize winner Venki Ramakrishnan, a molecular biologist who offers a balanced perspective on the anti-aging field. Ramakrishnan discusses various promising areas of anti-aging research, including caloric restriction drugs like rapamycin, senolytics to target senescent cells, and stem cell therapies. He emphasizes the importance of clinical trials and cautions against rushing into unproven treatments. The conversation covers lifestyle factors that can promote healthy aging, such as regular exercise, proper nutrition, and maintaining social connections. Ramakrishnan shares personal insights, including his father's experience of maintaining an active lifestyle until age 99. He also touches on his own career journey and winning the Nobel Prize. Throughout the interview, he stresses the need for a scientific approach to anti-aging research while acknowledging the urgency felt by many to combat aging. The podcast provides a thoughtful exploration of the current state of anti-aging science, balancing excitement for potential breakthroughs with the need for rigorous scientific validation. ***** Venki Ramakrishnan shared the 2009 Nobel Prize in Chemistry for uncovering the structure of the ribosome. A National Academy of Sciences member, Venki runs his research group at the MRC Laboratory of Molecular Biology in Cambridge, England. From 2015 to 2020, he served as president of the Royal Society, one of the world's oldest scientific organizations. He is the author of the frank scientific memoir Gene Machine: The Race to Decipher the Secrets of the Ribosome and Amazon bestselling book Why We Die: The New Science of Aging and the Quest for Immortality. ***** Cutting Edge Health podcast website: https://cuttingedgehealth.com/ Cutting Edge Health Social and YouTube: YouTube channel: youtube.com/@cuttingedgehealthpodcast Instagram - https://instagram.com/cuttingedgehealthpodcast Facebook - https://www.facebook.com/Cutting-Edge-Health-Podcast-with-Jane-Rogers-101036902255756 Please note that the information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Cutting Edge Health podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. Special thanks to Alan and Maria on the Cutting Edge Health team!
Join BrainStorm host Meryl Comer as she kicks off 2025 with "Rockstar of Science" Dr. Rudy Tanzi, the pioneering Director of Genetics and Aging Research and Director of the McCance Center for Brain Health at Mass General Hospital. Dr. Tanzi delves into the new FDA-approved drugs, early cognitive blood tests, and why treating Alzheimer's should mirror our approach to heart disease by focusing on prevention long before symptoms appear. Drawing from his decades of research, Dr. Tanzi shares his vision for the future: a simple daily pill that could prevent Alzheimer's just like statins prevent heart disease. Whether you are concerned about brain health or fascinated by cutting-edge medical science, this episode offers hope and practical wisdom from one of the field's most influential voices. You don't want to miss it!Support the show
La marche nordique, ou Nordic Walking, est une discipline sportive qui combine la marche rapide avec l'utilisation de bâtons spécialement conçus pour cette activité. Originaire de Finlande, elle a été développée dans les années 1930 comme entraînement estival pour les skieurs de fond. Contrairement à la marche classique, la marche nordique engage l'ensemble du corps, notamment les membres supérieurs grâce à l'utilisation dynamique des bâtons. Les bâtons, tenus dans chaque main, servent à propulser le corps en avant en synchronisation avec les pas, tout en maintenant une posture droite. Cette technique, simple mais efficace, augmente l'effort physique tout en répartissant les contraintes sur plusieurs groupes musculaires. La marche nordique se pratique sur des terrains variés : routes, sentiers ou même chemins forestiers, ce qui en fait une activité adaptable et accessible à tous les âges. La marche nordique offre une multitude de bienfaits pour la santé, tant physique que mentale : 1. Amélioration de la condition cardiovasculaire : La marche nordique augmente la fréquence cardiaque et améliore l'endurance, tout en réduisant les risques de maladies cardiovasculaires. 2. Renforcement musculaire : Contrairement à la marche classique, elle mobilise jusqu'à 90 % des muscles du corps, y compris ceux des bras, des épaules, du dos et des abdominaux. 3. Soulagement des articulations : Les bâtons réduisent l'impact sur les genoux, les hanches et la colonne vertébrale, ce qui la rend idéale pour les personnes souffrant de douleurs articulaires. 4. Amélioration de la posture et de l'équilibre : En sollicitant le haut du corps et en maintenant une posture droite, elle renforce les muscles posturaux. 5. Effet mental positif : Comme toute activité physique en plein air, elle aide à réduire le stress, l'anxiété et améliore le bien-être général. Une étude publiée dans le Journal of Aging Research (2013) a démontré que la marche nordique améliore significativement la capacité physique, la posture et la qualité de vie chez les seniors. Les participants ayant pratiqué cette activité pendant 12 semaines ont montré une augmentation de leur force musculaire, une meilleure coordination et une réduction de la fatigue. En résumé, la marche nordique est une activité complète, douce et accessible qui combine exercice physique et bienfaits psychologiques, adaptée à tous, qu'il s'agisse de débutants ou de sportifs confirmés. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Want to add a healthy habit to your daily routine that is absolutely free and incredibly effective? Looking to reduce insulin resistance and lose visceral fat? Want to boost mental health and improve cognitive function? Look no further than walking! Tune in to hear us unpack the myriad of research-supported benefits. In this episode, we discuss the incredible benefits of walking, from lowering blood pressure to improving heart rate variability to reducing stress and so much more. Learn about the magic number when it comes to step count, our thoughts on walking in nature vs. on a treadmill, and get practical tips for getting those steps! Also in this episode: Naturally Nourished Teas are buy 3 get 1 FREE, use code FREETEA Gift cards at Naturally Nourished Detox Masterclass 1/8 Keto Masterclass 1/15 Walking Pad C2 use code ALIMILLERRD for savings Health Benefits of Walking Lowers Blood Pressure Hypertension: Brisk walking for 30 minutes, five days a week reduces blood pressure (Hypertension, 2020). Improves Cholesterol Levels Cholesterol: Effects on LDL and HDL cholesterol (Journal of the American Heart Association, 2021). Lipid Profiles: Walking improves triglycerides and HDL (Atherosclerosis, 2021). Reduces the Risk of Coronary Artery Disease Coronary Artery Disease Risk: 150 minutes of walking weekly (Circulation, 2022). Enhances Cardiorespiratory Fitness Reduces Systemic Inflammation Systemic Inflammation: Walking lowers CRP and IL-6 (Arteriosclerosis, Thrombosis, and Vascular Biology, 2020). Systemic Inflammation: Walking reduces inflammatory cytokines (The Journal of Endocrinology, 2022). Helps Maintain Healthy Weight and Prevent Obesity Improves Heart Rate Variability Heart Rate Variability: HRV improvement with regular walking (Heart, 2022). Prevents Peripheral Artery Disease Peripheral Artery Disease: Walking improves circulation and function in PAD patients (Journal of Vascular Surgery, 2021). Reduces Resting Heart Rate Enhances Endothelial Function Supports Recovery After Cardiac Events Improves Insulin Sensitivity Insulin Sensitivity: Improvements with post-meal walks (Diabetes Care, 2021). Enhances Glucose Regulation Boosts Fat Oxidation Fat Oxidation: Brisk walking boosts fat metabolism (Journal of Applied Physiology, 2022). Reduces Visceral Fat Reduction of visceral fat after 10,000 steps/day (Obesity, 2021). Promotes Energy Balance Energy Balance: 12,000 steps/day for maintaining weight (Medicine & Science in Sports & Exercise, 2020). Regulates Hormones Related to Metabolism Increases Mitochondrial Efficiency Improves Metabolic Flexibility Prevents Metabolic Syndrome Helps Manage Type 2 Diabetes Mental health Stress Reduction: Nature walks lower cortisol more than treadmill (Environmental Research, 2022). Stimulates Neurogenesis and Brain Plasticity Brain Connectivity: Walking improves default mode network activity (Journal of Aging Research, 2021). Enhances Neurotransmitter Balance Supports Autonomic Nervous System Regulation Improves Sensory Integration Vestibular Function: Enhancing balance and stability with walking (Frontiers in Neuroscience, 2021). Strengthens Cognitive Function Neurogenesis and Cognitive Function: Exercise-induced brain growth (Nature Neuroscience, 2021). Promotes Myelination and Nerve Health Enhances Emotional Regulation via the Vagus Nerve Reduces Neurological Disease Risk Synchronizes the Nervous System Through Rhythmic Movement Improves Sleep and Circadian Rhythm Bone and Joint Health Immune System Support Longevity and Reduced Mortality Gut Health Gut Health: Positive effects on microbiota diversity (Gut Microbes, 2020). The Science of Step Counts Thoughts on Nature vs. Treadmill Walking Cognitive Benefits: Nature walking improves attention restoration (Nature Neuroscience, 2021). Proprioception: Benefits of uneven terrain in natural settings (Journal of Sports Medicine, 2023). Motivation: Outdoor walkers maintain habits better than treadmill users (Behavioral Medicine, 2022). Immune Boosting: Increased NK cell activity in forest walkers (International Journal of Environmental Health Research, 2021). Sponsors for this episode: According to extensive research by the Environmental Working Group, virtually every home in America has harmful contaminants in its tap water. That's why you've got to check out AquaTru. AquaTru purifiers use a 4-stage reverse osmosis purification process, and their countertop purifiers work with NO installation or plumbing. It removes 15x more contaminants than ordinary pitcher filters and are specifically designed to combat chemicals like PFAS in your water supply. Naturally Nourished Podcast listeners can use code ALIMILLERRD at AquaTru.com to save 20% off.
In this episode of the Healthy, Wealthy, and Smart Podcast, host Dr. Karen Litzy welcomes Phyllis Greenberger, co-founder and CEO of the Society for the Advancement of Women's Health Research. They delve into the longstanding issue of bias and discrimination in women's healthcare, a problem that has persisted for centuries. Phyllis shares insights into the historical context of women's health, highlighting how women were often viewed solely in terms of their reproductive capabilities and deemed too fragile for broader roles in society. This conversation sheds light on the systemic challenges faced by women, particularly minority women, in accessing equitable healthcare. Tune in for an enlightening discussion on the fight to overcome these barriers and improve health outcomes for all women. Time Stamps: [00:02:06] Discrimination in women's healthcare. [00:08:07] Women in clinical trials. [00:09:11] Women's health research disparities. [00:15:37] Women's health legislation progress. [00:21:49] Women's inclusion in research. [00:24:32] Heart health awareness for women. [00:30:06] Women's health advocacy in medicine. [00:34:55] Clinical trial accessibility improvements. [00:35:50] Women's health advocacy challenges. [00:40:28] AI and sex differences in research. [00:44:49] Don't take no for an answer. More About Phyllis Greenberger M.S.W.: Phyllis Greenberger is senior vice president of Science & Health Policy for Healthy Women. Previously, Phyllis was the president and CEO of the Society for Women's Health Research (SWHR), a national nonprofit organization widely recognized as the thought leader in women's health research, for 26 years. Phyllis was awarded the Trailblazer Award by the U.S. Department of Health and Human Services Office of Women's Health in 2016 and the Perennial Hero Award by the Alliance for Aging Research in 2021. Most recently, she received the Women in Government Relations Lifetime Achievement Award and has published a book, Sex Cells, about the fight to overcome bias and discrimination in women's healthcare. Resources from this Episode: Website Sex Cells the Book Phyllis on LinkedIn Phyllis on Facebook Phyllis on Instagram Phyllis on X Jane Sponsorship Information: Book a one-on-one demo here Mention the code LITZY1MO for a free month Follow Dr. Karen Litzy on Social Media: Karen's Twitter Karen's Instagram Karen's LinkedIn Subscribe to Healthy, Wealthy & Smart: YouTube Website Apple Podcast Spotify SoundCloud Stitcher iHeart Radio
Welcome to the Green Rush, a weekly conversation at the intersection of cannabis, psychedelics, the capital markets, and culture, produced by KCSA Podcast Labs. Today, we have a special episode featuring our newest production, Alternatively Speaking. In our debut season, we're diving into a revolutionary concept in health span, longevity, and healthcare. We met with Dr. Nir Barzilai, director of the Institute for Aging Research at the Albert Einstein College of Medicine and the Director of the Paul F. Glenn Center for the Biology of Human Aging Research and of the National Institutes of Health's (NIH) Nathan Shock Centers of Excellence in the Basic Biology of Aging. Dr. Barzilai discovered the first “longevity gene” in humans. His research established that the gene variant that leads to high HDL, or “good cholesterol,” is linked to healthy aging and extreme longevity. Treatments for age-related diseases like type 2 diabetes are being developed based on Dr. Barzilai's work and are currently in clinical trials. In addition to his “longevity gene” research, Dr. Barzilai studies key mechanisms involved in the biology of aging, including how nutrients and genetics influence lifespan. He is also investigating the physical and mental declines associated with aging and how they affect longevity. Dr. Barzilai is professor of medicine (endocrinology) and of genetics, a member of the Diabetes Research Center, and director of the Diabetes Research and Training Center's Animal Physiology core. Podcast Highlights: Introduction & Dr. Nir Barzilai's Groundbreaking Discovery (00:00 - 03:15): Overview of Dr. Nir Barzilai's discovery of the first “longevity gene” in humans and its link to healthy aging. Discussion on the significance of high HDL cholesterol and how it relates to extreme longevity. The Science Behind Longevity Genes (03:16 - 08:32): Dive into the specific genetic markers that contribute to longevity. Dr. Barzilai shares insights on the mechanisms of aging and the potential to delay or reverse age-related diseases. Current Clinical Trials on Age-Related Diseases (08:33 - 12:10): An exploration of the treatments for type 2 diabetes and other age-related conditions that are being developed from Dr. Barzilai's research, with an update on the progress of these clinical trials. Nutritional and Genetic Influence on Lifespan (12:11 - 17:48): How both genetics and nutrition shape our healthspan and longevity. Dr. Barzilai explains the latest findings on how diet can influence aging and the role of genetics in extending life. Mental and Physical Decline in Aging (17:49 - 21:22): Discussion on the common declines in physical and mental health with aging, and how they impact longevity. Dr. Barzilai talks about ongoing research into mitigating these declines. Future of Longevity Research (21:23 - 26:55): Dr. Barzilai shares his vision for the future of aging research, focusing on potential breakthroughs in longevity science. Social Media: @NirBarzilaiMD: https://x.com/nirbarzilaimd?lang=en https://www.linkedin.com/in/nir-barzilai-7a86a7212/ Other Links/Mentions/Resources: Age Later by Nir Barzilai, M.D. https://us.macmillan.com/books/9781250230867/agelater Albert Einstein College of Medicine https://einsteinmed.edu/faculty/484/nir-barzilai American Federation for Aging Research (AFAR) https://www.afar.org/ Aging is a Treatable Condition - Worth.com The 4 most promising anti-aging drugs investors are sleeping on, according to a leading longevity researcher - Business Insider What is your Biological Age? - The New York Times Show Credits: This episode was hosted by Anne Donohoe and Phil Carlson of KCSA Strategic Communications. Special thanks to our Program Director, Shea Gunther, and Executive Producer, Maria Petsanas. You can learn more about how KCSA can help your cannabis and psychedelic companies by visiting www.kcsa.com or emailing greenrush@kcsa.com.
A new poll examines presidential preferences for Oklahomans behind bars. Oklahoma researchers get a grant to study exercise and aging.McDonald's is bringing back the Quarter Pounder.You can find the KOSU Daily wherever you get your podcasts, you can also subscribe, rate us and leave a comment.You can keep up to date on all the latest news throughout the day at KOSU.org and make sure to follow us on Facebook, Twitter and Instagram at KOSU Radio.This is The KOSU Daily, Oklahoma news, every weekday.
Dr. David Furman is a key researcher at the Buck Institute for Research on Aging, where he focuses on understanding the underlying mechanisms of aging and chronic diseases, particularly through the lens of the immune system. His research centers around "inflammaging," the concept that low-grade, chronic inflammation contributes to the aging process and the development of age-related diseases like cardiovascular disease, neurodegenerative disorders, and metabolic syndromes. At the Buck Institute, Dr. Furman leads efforts to unravel how immune dysfunction plays a pivotal role in accelerating biological aging. His work integrates systems biology approaches, including advanced computational and bioinformatic tools, to analyze large datasets related to human immunity and inflammation. By understanding how these systems change over time, Dr. Furman aims to identify biomarkers of aging and develop therapeutic strategies to target inflammaging. In addition to his role at the Buck Institute, Dr. Furman is involved in the 1000 Immunomes Project, a large-scale initiative to map the immune systems of individuals across different age groups. This project has contributed significantly to the growing understanding of how the immune system deteriorates with age and how this process may be modifiable through intervention. Dr. Furman's work is influential in the longevity and biotech spaces, and he continues to be a thought leader in the development of anti-inflammatory therapies to extend healthspan and potentially delay the onset of age-related diseases. Timestamps 00:00 Introduction to Inflammation and Longevity 03:06 Understanding Inflammation and Aging 05:52 The Role of Environment in Inflammation 09:14 Ancestral Lifestyle Experiment 12:04 The Importance of Movement and Daily Activity 14:54 Nutrition and Its Impact on Health 18:14 The Future of Aging Research and AI 21:02 The Threat of Microplastics 23:53 Conclusion and Future Directions
Do you prefer multistory episodes, single story episodes, or a mix? Let us know! In this episode of 'Discover Daily' by Perplexity, we begin with a look at Adobe's latest innovation, the Firefly Video Model. This AI-powered toolset boasts video editing features like Generative Extend, now available in beta in Premiere Pro, and offers commercial safety and ethical considerations that may set it apart from competitors. We then shift to recent findings in longevity research, revealing that human life expectancy gains are slowing down and potentially approaching a biological limit. We discuss the implications of this research, including the concept of "healthspan" and the importance of quality of life over mere quantity of years. The episode's main focus is on NASA's Europa Clipper mission, which launched on October 14, 2024. The ambitious project will explore Jupiter's icy moon Europa, potentially one of the most promising places in our solar system to search for extraterrestrial life. We discuss the mission's objectives, the spacecraft's innovative design features, and the potential implications of discovering conditions suitable for life beneath Europa's frozen surface. This fascinating exploration of space science highlights the ongoing quest to understand our place in the universe and the potential for life beyond Earth.Perplexity is the fastest and most powerful way to search the web. Perplexity crawls the web and curates the most relevant and up-to-date sources (from academic papers to Reddit threads) to create the perfect response to any question or topic you're interested in. Take the world's knowledge with you anywhere. Available on iOS and Android Join our growing Discord community for the latest updates and exclusive content. Follow us on: Instagram Threads X (Twitter) YouTube Linkedin
On tonight's show, I have two guests. My first guest is Sue Peschin, president and CEO of the Alliance for Aging Research. She will be sharing about the importance of our older population protecting themselves against RSV as we face the fall/winter season. Ahead of National Leave a Review Day, I'll have Joe Burton, CEO of Reputation. Joe will be sharing about the importance of online reviews.
Welcome to the Green Rush, a weekly conversation at the intersection of cannabis, psychedelics, the capital markets, and culture, produced by KCSA Podcast Labs. Today, we have a special edition of the Green Rush featuring our newest production, Alternatively Speaking. In our debut season, we're diving into a revolutionary concept in health span, longevity, and healthcare. Our hosts sat down with Alternatively Speaking's first-ever guest, Jamie Justice, Executive Vice President of the Health Domain at XPRIZE Foundation and Adjunct Professor in Internal Medicine Section on Gerontology and Geriatric Medicine, and Sticht Center on Healthy Aging and Alzheimer's Prevention at Wake Forest University School of Medicine (WFUSM). Jamie is dedicated to Geroscience research that advances the hypothesis that by targeting the basic biology of aging the incidence of multiple age-related diseases can be delayed or prevented. So don't sit back, lean forward and enjoy! Podcast Highlights: Introduction & XPRIZE Foundation Origins (00:00 - 02:29): Overview of the longevity industry, the impact of the Ansari XPRIZE on private space travel, and XPRIZE's influence on companies like SpaceX. Jamie Justice's Background & Passion for Research (02:30 - 06:14): Jamie's journey into gerontology, early research experiences with older adults, and her focus on empathy and the human aspect of aging. Exploring Aging & Longevity (06:15 - 10:21): Discussion on the fundamental questions of aging, how different interventions (lifestyle, supplements, drugs) impact human health and longevity. Translating Aging Research into Practice (10:22 - 13:10): Jamie's work at Wake Forest, ongoing efforts to apply aging research in real-world settings, and the philosophical aspects of aging—living fully versus focusing on death. Healthspan vs. Lifespan & Longevity Goals (13:11 - 20:43): Exploring the concept of the ‘longevity dividend,' aligning biological health with extended life, and the strategies to improve healthspan by optimizing current biology. XPRIZE HealthSPAN Award & Future of Aging Research (20:44 - 28:28): Introduction to the XPRIZE HealthSPAN Award program, the bold scientific goals it supports, challenges in aging research, and the collaborative efforts to advance the field. Social Media: X: @j_n_justice LinkedIn: https://www.linkedin.com/in/jamie-justice-ph-d-6b933146/ Other Links/Mentions: https://www.xprize.org/ https://www.xprize.org/prizes/healthspan Show Credits: This episode was hosted by Anne Donohoe of KCSA Strategic Communications. Special thanks to our Program Director, Shea Gunther and Executive Producer, Maria Petsanas. You can learn more about how KCSA can help your cannabis and psychedelic companies by visiting www.kcsa.com or emailing greenrush@kcsa.com. You can also connect with us via our social channels: X: @KCSAPodcastLabs Instagram: @KCSAPodcastLabs LinkedIn: https://www.linkedin.com/company/kcsapodcastlabs/
Title: Longevity Conferences (ARDD and Dublin Longevity) Quote: “Its not what you know but who you know”Said by many across multiple cultures Today we review:The Aging Research and Drug Discovery Conference in Copenhagen, DenmarkThe Dublin Longevity Summit in Dublin, Ireland 3 Plugs- keep moving until you find your place and your people- go to places where you can be useful and contribute- try not to lose what makes you, you along the way. Hallmarks of Both Conferences- I highly recommend attending both of these events (and conferences in general)- Europe was a blast. People are out and about. The downtowns I went to were generally flourishing - Work Hard Play Hard – Lots of lectures, lots of late nights at the bar- All Day Every Day- Leaders in the field of Longevity Research (highly research focussed)- Research Focused, Less Clinical (but still some clinical content)- Startups and Funding/Funders was a big focus- Eccentric Personalities- Lots of Fun! Met a lot of great people See full blog post at fullscope.org and longetrics.org
In this episode of the Gladden Longevity Podcast, Steve Reiter and Dr. Gladden explore various aspects of food safety, the concept of regenerative farming, staying young and living young for a lifetime instead of ‘healthy aging', the misconceptions surrounding ‘healthy aging', and the role of self-care in maintaining vitality. The conversation also touches on the latest advancements in aging research and the potential for breakthroughs in longevity science. Dr. Gladden explains why he is so sure that the code on aging will be cracked within the next 3 to 5 years and the cutting-edge technologies being added to Gladden Longevity. For the audience · Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ ! Takeaways · Living young for a lifetime requires mindset work. · The food supply is often contaminated with pesticides. · Regenerative farming improves food quality by building up the soil. · Regenerative farming practices eliminate the need for fertilizers and pesticides. · Nutrition and protein quality for muscle maintenance. · ‘Healthy aging' is actually NOT the goal. · Aging research is rapidly advancing, doubling every three months. · Self-care encompasses physical, mental, and spiritual well-being. Chapters 00:00 Introduction to Age Hacking and Longevity 02:46 The Importance of Mindset in Recovery 04:11 Food Safety and Environmental Toxins 05:38 The Promise of Regenerative Farming 05:56 The Journey of Regenerative Farming 14:17 Redefining Healthy Aging 19:54 Cracking the Code on Aging 24:10 The Importance of Self-Care 26:28 Goodbye Articles, News and Supplements mentioned Food Safety Education * EXPERTS WANT FDA TO DO MORE TO ENSURE FOOD SAFETY https://www.medpagetoday.com/special-reports/features/111872 * CONSUMERS ARE WEARY OF PESTICIDE RESIDUE IN FRUITS AND VEGETABLES, FIVE-COUNTRY STUDY FINDS https://phys.org/news/2024-09-consumers-wary-pesticide-residue-fruits.amp * FOOD SCIENTIST DEBUNKS 5-SECOND RULE – HERE'S WHAT YOU NEED TO KNOW https://www.delish.com/kitchen-tools/kitchen-secrets/a62138112/five-second-rule-food-science/ * ITEMS THAT DON'T BELONG IN THE FRIDGE https://www.dailymail.co.uk/sciencetech/article-13838551/amp/Can-spot-items-dont-belong-fridge-60-seconds-Half-people-fail-brainteaser.html?ito=smartnews Healthy Aging * LET THIS 74-YEAR-OLD GRANDMA BE YOUR INSPIRATION FOR HEALTHY AGING https://www.facebook.com/share/v/swAFnup6vvHPwpWV/?mibextid=CTbP7E * WHAT IS GLUTATHIONE, THE ‘NEWEST AGE REVERSAL TREND' – AND GWYNETH PALTROW'S FOUNTAIN OF YOUTH? https://nypost.com/2024/09/11/lifestyle/what-is-glutathione-the-newest-age-reversal-trend-and-gwyneth-paltrows-fountain-of-youth/?utm_source=smartnews&utm_campaign=nypost&utm_medium=referral * THIS OIL IS TOP NOTCH FOR AGING SKIN, ACCORDING TO RESEARCH https://www.mindbodygreen.com/articles/why-moringa-oil-is-for-aging-skin-according-to-research * NUTRITION AND HEALTHY AGING: THE ROLE OF PROTEIN QUALITY IN COMBATING MUSCLE LOSS https://medicalxpress.com/news/2024-09-nutrition-healthy-aging-role-protein.html * DR. GLADDEN'S TOP 3 HACKS FOR LONGEVITY https://www.tiktok.com/t/ZTFLdB7rX/ * MEET THE 62-YEAR-OLD WHO'S AGING BACKWARDS https://youtu.be/qI6aTAicRmw?si=jc1VqhrCm9ZHHkuu Supplements PERFECT AMINOS https://gladdenlongevityshop.com/products/perfect-amino-coated-tablets-300ct?_pos=2&_psq=perfect&_ss=e&_v=1.0 Send your Qs for future episodes! Email: podcast@gladdenlongevity.com Reach out to us at: Website: https://gladdenlongevity.com/ Facebook: https://www.facebook.com/Gladdenlongevity/ Instagram: https://www.instagram.com/gladdenlongevity/?hl=en LinkedIn: https://www.linkedin.com/company/gladdenlongevity YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw
How do you unlock the mysteries of aging?
Medicare is betting that taking care of the caregiver will help dementia patients stay at home longer. Patients and their caregivers are often left to navigate the confusing world of dementia by themselves, but Medicare is launching a new program to change that.Guests:Malaz Boustani, MD, PhD, Founding Director, Sandra Eskenazi Center for Brain Care Innovation; Professor of Aging Research, Indiana University School of Medicine Rosanne Corcoran, Caregiver Liz Fowler, PhD, JD, Director of CMMI and Deputy Administrator, Centers for Medicare and Medicaid Services Cindi Hart, Caregiver Alex Olgin, Reporter/Producer, Tradeoffs Lauren Sullivan, Care Coordinator, Eskenazi Health Learn more and read a full transcript on our website.Want more Tradeoffs? Sign up for our free weekly newsletter featuring the latest health policy research and news.Support this type of journalism today, with a gift.Follow us on Twitter. Hosted on Acast. See acast.com/privacy for more information.
Satchidananda (Satchin) Panda, PhD discusses the impact of food timing on health, advocating for personalized eating windows and gradual changes to fasting routines. Dr. Panda and Dr. Mindy explore the relationship between fasting, metabolic health, and gut microbes, emphasizing the importance of lifestyle factors like sleep, exercise, and diverse gut microbiota for overall well-being. Dr. Panda shares tips on adjusting to different time zones to support metabolic health during travel, highlighting the holistic approach to health through healthy daily routines. To view full show notes, more information on our guests, resources mentioned in the episode, discount codes, transcripts, and more, visit https://drmindypelz.com/ep236 Satchidananda (Satchin) Panda, PhD is a Professor at the Salk Institute in California, where his research focuses on the circadian regulation of behavior, physiology, and metabolism in model organisms and in humans. Dr. Panda discovered a blue-light sensing cell type in the retina entrains our master circadian clock, affects mood, and regulates the production of the sleep hormone melatonin. Recently, he discovered that maintaining a daily feeding-fasting cycle – popularly known as time-restricted feeding (TRF) – can prevent and reverse metabolic diseases. Based on a feasibility study in humans, his lab is currently carrying out a smartphone-based study to assess the extent of circadian disruption among adults. Dr. Panda has received the Julie Martin Mid-Career Award in Aging Research, the Dana Foundation Award in Brain and Immune System Imaging, and was a Pew Scholar in the Biomedical Sciences Check out our fasting membership at resetacademy.drmindypelz.com. Please note our medical disclaimer.
Donate (no account necessary) | Subscribe (account required) Dive into today's episode of The Wright Report as Bryan Dean Wright takes you on a global journey, starting with the latest Biden family dramas unfolding in the media. Discover Hunter Biden's legal battle against Fox News, aiming to address alleged revenge porn violations and misinformation. Meanwhile, President Joe Biden collaborates with Mexico's President to tackle illegal migration, but with a nuanced focus on non-Mexican migrants. Transitioning from the Americas, we head to Mexico for an update on the ongoing cartel wars, which might soon impact your avocado and berry prices. In Asia, we cover the political winds shifting in the Solomon Islands against China and a severe heat wave affecting the region. Back in Europe, delve into Germany's struggle with 'Dirty Green Energy' and the rise of radical Islam. On the domestic front, there's promising news for the golden years: new research suggests ways to maintain brain function as you age. Lastly, get a sneak peek at the exorbitant costs associated with building a pier off the Gaza Strip, which has escalated far beyond initial projections. Stay tuned as we connect the dots between these global events and what they mean for you.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Alex Aravanis is a leader in research and development of technologies and clinical tests utilizing the latest tools in DNA analysis and data science. In this episode, Alex delves into two interconnected topics: liquid biopsies and epigenetics. He begins by tracing the trajectory of genome sequencing and tumor sequencing, setting the stage for a detailed exploration of liquid biopsies as an early cancer detection method. The discussion encompasses key concepts such as cell-free DNA, DNA methylation, sensitivity, specificity, and the predictive values associated with liquid biopsies. Transitioning to epigenetics, Alex examines the intricate interplay of DNA methylation and aging biology and explores the possibility of using cellular reprogramming to reverse epigenetic changes that occur with aging. We discuss: Alex's background in applying engineering to problems in medicine [3:15]; A primer on human genetics, and the history and current landscape of DNA sequencing [11:00]; The advent and evolution of liquid biopsies for early detection of cancer [23:15]; The role of cell-free DNA in cancer detection: how incidental findings in non-invasive prenatal testing led to the development of liquid biopsies [40:15]; The development of a universal blood test for cancer detection and a discussion of specificity of tests [46:00]; Advancements in cell-free DNA analysis and development of a multi-cancer screening test at GRAIL [51:00]; DNA methylation explained [58:15]; Optimizing cancer detection with methylation analysis of cfDNA in small blood samples [1:02:45]; The importance of understanding sensitivity, specificity, positive predictive value, and negative predictive value in cancer screening [1:08:00]; The performance of the GRAIL Galleri test and its ability to detect various types and stages of cancer [1:21:00]; Do early cancer detection methods, like liquid biopsies, translate to improvement in overall survival? [1:27:45]; The role of epigenetics in aging [1:39:30]; How cell-free DNA methylation patterns can help identify a cancer's tissue of origin [1:45:30]; Cellular and epigenetic reprogramming and other exciting work in the field of aging [1:52:30]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
Sleep is powerful. You've probably heard this statement a thousand times. It's all over the books, media, podcasts, videos, everywhere. But many of us still lack a deep understanding of its power and how to use it for our benefit. In today's episode, 3 guests dive deeper into understanding the amazing human mind and how sleep is critical to operating at 100% mental capacity. We talk about how to unlock its power — particularly during really hectic seasons of life.Andrew Huberman is a neuroscientist at Stanford University. He also runs the Huberman Lab, which studies how the brain functions, how it changes through experiences, and how to repair the brain after injury or disease. David Sinclair is a tenured Professor in the Department of Genetics at the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School and serves as President of the Academy for Health and Lifespan Research. He is best known for his work on understanding why we age and how to slow its effects.Dr. Matthew Walker earned his degree in neuroscience from Nottingham University, UK, and his Ph.D. in neurophysiology from the Medical Research Council in London. Dr. Walker researches the impact of sleep on human health and disease, and he's written the international bestseller, Why We Sleep, unlocking the power of sleep and dreams.In this episode you will learnHow inadequate sleep impacts brain function and overall mental health.The ideal amount of sleep necessary for optimal health and well-being.The effects of a poor diet on sleep quality, even when you're getting sufficient sleep, compared to the impact of a good diet on nights of poor sleep.Ways to influence and potentially control the nature of your dreams.Techniques to train your brain for more frequent lucid dreaming experiences.For more information go to www.lewishowes.com/1545For more Greatness text PODCAST to +1 (614) 350-3960Listen to the full episodes here:Andrew Huberman – https://link.chtbl.com/1219-podDavid Sinclair – https://link.chtbl.com/1004-guestMatthew Walker – https://link.chtbl.com/1476-pod