Podcasts about Organ

In dieser Hörerfragen-Folge beantworten Benjamin und Peter zwei häufige Anliegen aus der Praxis. Zuerst geht es um Autoimmunhepatitis und die Frage, ob und wie der Heilpilz Huaier (Trametes robiniophila) begleitend eingesetzt werden kann, inklusive praktischer Dosierüberlegungen und möglicher Ergänzungen zur Leberunterstützung. Dabei wird auch die Rolle von Darm und Immunsystem in einfachen Worten erklärt und warum Regulation nicht nur „am Organ“, sondern im Gesamtsystem gedacht wird. Im zweiten Teil dreht sich alles um dünner werdendes Haar: Welche Nährstoffe typischerweise eine Rolle spielen können, wie man den Fokus sinnvoll setzt und welche alltagstauglichen Maßnahmen sich naturheilkundlich ableiten lassen. Die Folge liefert Impulse zur Ergänzung einer medizinischen Abklärung, ersetzt aber keine Diagnostik oder Therapie. Möchtest Du diesen Podcast finanziell unterstützen? Danke! Nutze ganz einfach paypal oder unsere Bankverbindung: Paypal Adresse: wirdunatur@online.de oder direkt über den Link: https://www.paypal.com/donate/?hosted_button_id=GMQBVKBLBD2FY Kontoinhaber: MW Medien und Entertainment UG IBAN: DE12 1001 0010 0665 4301 33 BIC: PBNKDEFFXXX Verwendungszweck: Freiwillige Unterstützung oder Zuwendung Besuche auch unsere Homepage https://wir-du-natur.de und trage Dich zu unserem Newsletter ein. So bist Du immer auf dem neuesten Stand und kannst mit uns in Kontakt bleiben. Wichtiger Hinweis (Disclaimer): Liebe Hörer, die Nutzung der Inhalte dieses Podcast erfolgt auf Eure eigene Gefahr und ist nur zur allgemeinen Information bestimmt. Bei Erkrankungen oder anhaltenden Beschwerden wird die individuelle Beratung durch einen Arzt oder Heilpraktiker zwingend empfohlen. Die in diesem Podcast zusammengestellten Informationen stellen in keiner Weise Ersatz für professionelle Beratungen und/oder Behandlungen durch Ärzte oder Heilpraktiker dar. Wir stellen keine Diagnosen und erteilen ausdrücklich keine Ratschläge oder Empfehlungen hinsichtlich der Therapie konkreter Erkrankungen. Für etwaige Angaben über Verfahrensweisen und Anwendungsformen wird von uns keine Gewähr übernommen und jede Anwendung erfolgt auf eigene Gefahr des Hörers. Bitte achtet auf Euch und wendet Euch bei persönlichen Anwendungsfragen vertrauensvoll an einen naturheilkundlichen Arzt oder Heilpraktiker. Wir sind in keiner Weise verantwortlich für etwaige Schädigungen, die durch den Gebrauch oder Missbrauch der dargestellten Inhalte entstehen. Ihr seid für Eure Gesundheit stets selbst verantwortlich.

Welcome back to Frontier Scum! After a run in with a human animal hybrid mortally wounded Crusty is injected with a mysterious elixir in a strange lab carriage, compliments of a doctor. She's got a brand new set of teeth and her bullet wounds are healed but within a disembodied voice rattles through her mind with just one thing to say... KILL THE ENGINE! Pick up Frontier Scum here: https://gamesomnivorous.com/pages/frontier-scum Community Discord: https://discord.gg/z2NW53APFa Merch: https://mystery-quest-shop.fourthwall.com/en-gbp Members and Patrons get $7 off your order - that's like a free membership along with your stylish new adventuring attire! Become a member: https://www.youtube.com/channel/UCd5_xAWJ4yX6NZ5cZaccqPw/join Podcast: https://www.pickaxe.uk/mystery-quest Patreon link: https://www.patreon.com/MysteryQuest Follow the Cast: Tom: https://www.youtube.com/angorytom Smith: https://youtube.com/hatfilms Ross: https://www.youtube.com/@hatfilms Lydia: https://www.twitch.tv/squidgame Ravs: https://www.twitch.tv/ravs_ Editing & Sound Design: Oscar Henderson Thumbnail Art: Jack Bailey Learn more about your ad choices. Visit podcastchoices.com/adchoices

In dieser Folge erwartet dich ein Thema, das besonders wichtig ist, wenn du dich für Detox interessierst. Viele Frauen erleben in den Wechseljahren plötzliche Umschwünge, obwohl sie ihren Alltag nicht bewusst verändert haben. Ein ausschlaggebender Grund dafür kann die Leber sein. In der heutigen Podcastfolge spreche ich darüber, warum dieses Organ in der Peri- und Menopause eine wichtige Schlüsselrolle spielt und weshalb sie maßgeblich für die körperlichen und mentalen Veränderungen in den Wechseljahren verantwortlich ist. Ich gehe auf interessante Themen ein und kläre Fragen wie: Warum kann eine überlastete Leber Heißhunger und Bauchfett begünstigen? Weshalb sind radikale Detox-Kuren oft kontraproduktiv? Und wie unterstütze ich durch Stressreduktion im Alltag meine Leber sanft und hormonfreundlich? Wenn du verstehen möchtest, warum Abnehmen ab 40 oft schwieriger wird und was dein Stoffwechsel jetzt wirklich braucht, ist diese Folge für dich. Du erfährst: ✨ warum Blutzuckerschwankungen in den Wechseljahren zunehmen ✨ wie die Leber den Östrogenstoffwechsel beeinflusst ✨ weshalb eine überlastete Leber Heißhunger und Bauchfett begünstigen kann ✨ warum Detox-Kuren oft kontraproduktiv sind ✨ wie du deine Leber sanft und hormonfreundlich unterstützt

Organ meats were once a valued staple in traditional diets, prized for their nutrient density and role in human health. Chef James Barry explains how they fell out of favor, why they matter more now than ever, and practical ways to bring them back into modern eating. He gives simple methods for using organ meats more regularly and helping you and your family over any initial aversion. Reference Links https://informedchoicewa.substack.com/ https://eatnakedkitchen.com/about/ ICWA's Amazon affiliate link to the Pluck product line: https://amzn.to/49IyFv3. Disclaimer: Informed Choice Washington earns a commission at no extra cost to you when you shop for Pluck or anything else starting at the foregoing link.

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3290: Nicole Poidevin breaks down the varying iron requirements across life stages and dietary preferences, highlighting the challenges and solutions for vegans and vegetarians. Learn which foods offer the best sources of haem and non-haem iron, and how to optimize iron absorption through simple dietary pairings and timing tips. Read along with the original article(s) here: https://www.idealnutrition.com.au/iron-deficiency-are-you-at-risk/ Quotes to ponder: "Organ meats such as liver are extremely nutritious, containing high amounts of iron and other nutrients." "Eating foods high in Vitamin C with those high in iron can greatly enhance absorption." "Avoiding tea and coffee with meals can also be beneficial as the tannins in these beverages can bind to iron and inhibit absorption by as much as 50%." Episode references: Nutrient Reference Values for Iron: https://www.nrv.gov.au/nutrients/iron Learn more about your ad choices. Visit megaphone.fm/adchoices

Discover all of the podcasts in our network, search for specific episodes, get the Optimal Living Daily workbook, and learn more at: OLDPodcast.com. Episode 3290: Nicole Poidevin breaks down the varying iron requirements across life stages and dietary preferences, highlighting the challenges and solutions for vegans and vegetarians. Learn which foods offer the best sources of haem and non-haem iron, and how to optimize iron absorption through simple dietary pairings and timing tips. Read along with the original article(s) here: https://www.idealnutrition.com.au/iron-deficiency-are-you-at-risk/ Quotes to ponder: "Organ meats such as liver are extremely nutritious, containing high amounts of iron and other nutrients." "Eating foods high in Vitamin C with those high in iron can greatly enhance absorption." "Avoiding tea and coffee with meals can also be beneficial as the tannins in these beverages can bind to iron and inhibit absorption by as much as 50%." Episode references: Nutrient Reference Values for Iron: https://www.nrv.gov.au/nutrients/iron Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode goes to 11, Spinal Tap style! Tani and Auk breakdown the new Pivot Shuttle LT and continue their discussion on the Rallon RS. Tani talks pain threshold when elaborating on the kidney stone he's dealing with. Also, there's a clean up day in the Santa Anas coming up and a shop ride at Luiseno Bike Park in San Diego! #mountainbiking #mtb #mtblife #ebike #ebikelife #ocmtba #downhillmtb #lovethebikeyouride #podcast #bikelife #bike #bikelover #localtrails #santaanamountains #bikeclub #orbea Check out The Path Bike Shop website: https://www.thepathbikeshop.com/ Follow The Path on Instagram: / thepathbikeshop Subscribe to our weekly newsletter: https://www.thepathbikeshop.com/pages... 

Dr. Jeanine Cook-Garard talks to Sophia Aidiniou, a health education professor at Nassau Community College who collaborates with local health organizations to bring real-world experiences into their classroom. For over 15 years, she has been dedicated to raising awareness about organ donation, and she received the “Making a Difference in the Community” award for their efforts in saving hundreds of lives throughout her career.  She also talks to one of her Community Health students, Gabriella Ibarra-Sanchez, who is a two-time organ recipient.

Josh's guests: Pete Kennedy, J.D. - Report of Michigan Fresh Unprocessed Whole Milk How raw unpasteurized milk helps protect our health, what are the downside risks Wouter Bijdenijk - author, Plant Power The history of European medicinal plants Josh Lane Problems associated with the use of Organ transplants, new findings find us at: www.HeresToYourHealthWithJoshuaLane.com  

Dr. Pedro Barata and Dr. Ugwuji Maduekwe discuss the evolving treatment landscape in gastroesophageal junction and gastric cancers, including the emergence of organ preservation as a selective therapeutic goal, as well as strategies to mitigate disparities in care. Dr. Maduekwe is the senior author of the article, "Organ Preservation for Gastroesophageal Junction and Gastric Cancers: Ready for Primetime?" in the 2026 ASCO Educational Book. TRANSCRIPT Dr. Pedro Barata: Hello, and welcome to By the Book, a podcast series from ASCO that features compelling perspectives from authors and editors of the ASCO Educational Book. I'm Dr. Pedro Barata. I'm a medical oncologist at University Hospitals Seidman Cancer Center and an associate professor of medicine at Case Western Reserve University in Cleveland, Ohio. I'm also the deputy editor of the ASCO Educational Book. Gastric and gastroesophageal cancers are the fifth most common cancer worldwide and the fourth leading cause of cancer-related mortality. Over the last decade, the treatment landscape has evolved tremendously, and today, organ preservation is emerging as an attainable but still selective therapeutic goal. Today, I'm delighted to be speaking with Dr. Ugwuji Maduekwe, an associate professor of surgery and the director of regional therapies in the Division of Surgical Oncology at the Medical College of Wisconsin. Dr. Maduekwe is also the last author of a fantastic paper in the 2026 ASCO Educational Book titled "Organ Preservation for Gastroesophageal Junction and Gastric Cancers: Ready for Prime Time?" We explore these questions in our conversations today.  Our full disclosures are available in the transcript of this episode as well. Welcome. Thank you for joining us today. Dr. Ugwuji Maduekwe: Thank you, Dr. Barata. I'm really, really glad to be here. Dr. Pedro Barata: There's been a lot of progress in the treatment of gastric and gastroesophageal cancers. But before we actually dive into some of the key take-home points from your paper, can you just walk us through how systemic therapy has emerged and actually allowed you to start thinking about a curative framework and really informing surgery decision-making? Dr. Ugwuji Maduekwe: Great, thank you. I'm really excited to be here and I love this topic because, I'm terrified to think of how long ago it was, but I remember in medical school, one of my formative experiences and why I got so interested in oncology was when the very first trials about imatinib were coming through, right? Looking at the effect, I remember so vividly having a lecture as a first-year or second-year medical student, and the professor saying, "This data about this particular kind of cancer is no longer accurate. They don't need bone marrow transplants anymore, they can just take a pill." And that just sounded insane. And we don't have that yet for GI malignancies. But part of what is the promise of precision oncology has always been to me that framework. That framework we have for people with CML who don't have a bone marrow transplant, they take a pill. For people with GIST. And so when we talk about gastric cancers and gastroesophageal cancers, I think the short answer is that systemic therapy has forced surgeons to rethink what "necessary" really means, right? We have the old age saying, "a chance to cut is a chance to cure." And when I started out, the conversation was simple. We diagnose the cancer, we take it out. Surgery's the default. But what's changed really over the last decade and really over the last five years is that systemic therapy has gotten good enough to do what is probably real curative work before we ever enter the operating room. So now when you see a patient whose tumor has essentially melted away on restaging, the question has to shift, right? It's no longer just, "Can I take this out?" It's "Has the biology already done the heavy lifting? Have we already given them systemic therapy, and can we prove it safely so that maybe we don't have to do what is a relatively morbid procedure?" And that shift is what has opened the door to organ preservation. Surgery doesn't disappear, but it becomes more discretionary. Necessary for the patients who need it, and within systems that can allow us to make sure that we're giving it to the right patients. Dr. Pedro Barata: Right, no, that makes total sense. And going back to the outcomes that you get with these systemic therapies, I mean, big efforts to find effective regimens or cocktails of therapies that allow us to go to what we call "complete response," right? Pathologic complete response, or clinical complete response, or even molecular complete response. We're having these conversations across different tumors, hematologic malignancies as well as solid tumors, right? I certainly have those conversations in the GU arena as well. So, when we think of pathologic CRs for GI malignancies, right? If I were to summarize the data, and please correct me if I'm wrong, because I'm not an expert in this area, the traditional perioperative chemo gives you pCRs, pathologic complete response, in the single digits. But then when you start getting smarter at identifying biologically distinct tumors such as microsatellite instability, for instance, now you start talking about pCRs over 50%. In other words, half of the patients' cancer goes away, it melts down by offering, in this case, immunotherapy as a backbone of that neoadjuvant. But first of all, this shift, right, from going from these traditional, "not smart" chemotherapy approaches to kind of biologically-driven approaches, and how important is pCR in the context of "Do I really need surgery afterwards?" Dr. Ugwuji Maduekwe: That's really the crux of the entire conversation, right? We can't proceed and we wouldn't be able to have the conversation about whether organ preservation is even plausible if we hadn't been seeing these rates of pathologic complete response. If there's no viable tumor left at resection, did surgery add something? Are we sure? The challenge before this was how frequently that happened. And then the next one is, as you've already raised, "Can we figure that out without operating?" In the traditional perioperative chemo era, pathologic complete response was relatively rare, like maybe one in twenty patients. When we go to more modern regimens like FLOT, it got closer to one in six. When you add immunotherapy in recent trials like MATTERHORN, it's nearly triple that rate. And it's worth noting here, I'm a health services-health disparities researcher, so we'll just pause here and note that those all sound great, but these landmark trials have significant representation gaps that limit and should inform how confidently we generalize these findings. But back to what you just said, right, the real inflection point is MSI-high disease where, with neoadjuvant dual-checkpoint blockade, trials like NEONIPIGAS and INFINITY show pCR rates that are approaching 50% to 60%. That's not incremental progress, that's a whole new different biological reality. What does that mean? If we're saying that 50% to 60% of the people we take to the OR at the time of surgery will end up having no viable tumor, man, did we need to do a really big surgery? But the problem right now is the gold standard, I think we would mostly agree, the gold standard is pathologic complete response, and we only know that after surgery. I currently tell my patients, right, because I don't want them to be like, "Wait, we did this whole thing." I'm like, "We're going to do this surgery, and my hope is that we're going to do the surgery and there will be no cancer left in your stomach after we take out your stomach." And they're like, "But we took out my stomach and you're saying it's a good thing that there's no cancer." And yes, right now that is true because it's a measure of the efficacy of their systemic therapy. It's a measure of the biology of the disease. But should we be acting on this non-operatively? To do that, we have to find a surrogate. And the surrogate that we have to figure out is complete clinical response. And that's where we have issues with the stomach. In esophageal cancer, the preSANO protocol, which we'll talk about a little bit, validated a structured clinical response evaluation. People got really high-quality endoscopies with bite-on biopsies. They got endoscopic ultrasounds. They got fine-needle aspirations and PET-CT, and adding all of those things together, the miss rate for substantial residual disease was about 10% to 15%. That's a number we can work with. In the stomach, it's a lot more difficult anatomically just given the shape of people's stomachs. There's fibrosis, there's ulceration. A fair number of stomach and GEJ cancers have diffuse histology which makes it difficult to localize and they also have submucosal spread. Those all conceal residual disease. I had a recent case where I scoped the patient during the case, and this person had had a 4 cm ulcer prior to surgery, and I scoped and there was nothing visible. And I was elated. And on the final pathology they had a 7 cm tumor still in place. It was just all submucosal. That's the problem. I'm not a gastroenterologist, but I would have said this was a great clinical response, but because it's gastric, there was a fair amount of submucosal disease that was still there. And our imaging loses accuracy after treatment. So the gap between what looks clean clinically and what's actually there pathologically remains very wide. So I think that's why we're trying to figure it out and make it cleaner. And outside of biomarker-selected settings like MSI-high disease, in general, I'm going to skip to the end and our upshot for the paper, which is that organ preservation, I would say for gastric cancer particularly, should remain investigational. I think we're at the point where the biology is increasingly favorable, but our means of measurement is not there yet. Dr. Pedro Barata: Gotcha. So, this is a perfect segue because you did mention the SANO, just to spell it out, "Surgery As Needed for Oesophageal" trial, so SANO, perfect, I love the abbreviation. It's really catchy. It's fantastic, it's actually a well-put-together perspective effort or program applying to patients. And can you tell us how was that put together and how does that work out for patients? Dr. Ugwuji Maduekwe: Yeah, I think for those of us in the GI space, we have SANO and then we also have the OPRA for rectum. SANO for the upper GI is what takes organ preservation from theory to something that's clinically credible. The trial asked a very simple question. If a patient with a GEJ adenocarcinoma or esophageal adenocarcinoma achieved what was felt to be a clinical complete response after chemoradiation, would they actually benefit from immediate surgery? And the question was, "Can you safely observe?" And the answer was 'yes'. You could safely observe, but only if you do it right. And what does that mean? At two years, survival with active surveillance was not inferior to those who received an immediate esophagectomy. And those patients had a better early quality of life. Makes sense, right? Your quality of life with an esophagectomy versus not is going to be different. That matters a lot when you consider what the long-term metabolic and functional consequences of an esophagectomy are. The weight loss, nutritional deficiencies that can persist for years. But SANO worked because it was very, very disciplined and not permissive. You mentioned rigor. They were very elegant in their approach and there was a fair amount of rigor. So there were two main principles. The first was that surveillance was front-loaded and intentional. So they had endoscopies with biopsies and imaging every three to four months in the first year and then they progressively spaced it out with explicit criteria for what constituted failure. And then salvage surgery was pre-planned. So, the return-to-surgery pathway was already rehearsed ahead of time. If disease reappeared, take the patient to the OR within weeks. Not sit, figure out what that means, think about it a little bit and debate next steps. They were very clear about what the plan was going to be. So they've given us this blueprint for, like, watching people safely. I think what's remarkable is that if you don't do that, if you don't have that infrastructure, then organ preservation isn't really careful. It's really hopeful. And that's what I really liked about the SANO trial, aside from, I agree, the name is pretty cool. Dr. Pedro Barata: Yeah, no, that's a fantastic point. And that description is spot on. I am thinking as we go through this, where can this be adopted, right? Because, not surprisingly, patients are telling you they're doing a lot better, right, when you don't get the esophagus out or the stomach out. I mean, that makes total sense. So the question is, you know, how do you see those issues related to the logistics, right? Getting the multi-disciplinary team, getting the different assessments of CR. I guess PETs, a lot of people are getting access to imaging these days. How close do you think this is, this kind of program, to be implemented? And maybe I would assume it might need to be validated in different settings, right, including the community. How close or how far do you think you see that being applied out there versus continuing to be a niche program, watch and wait program, in dedicated academic centers? Dr. Ugwuji Maduekwe: I love this question. So I said at the top of this, I'm a health equity/health disparities researcher, and this is where I worry the most. I love the science of this. I'm really excited about the science. I'm very optimistic. I don't think this is a question of "if," I think it's a question of "when." We are going to get to a point where these conversations will be very, very reasonable and will be options. One of the things I worry about is: who is it going to be an option for? Organ preservation is not just a treatment choice, and I think what you're pointing out very rightly is it's a systems-level intervention. Look at what we just said for SANO. Someone needs to be able to do advanced endoscopy, get the patients back. We have to have the time and space to come back every three to four months. We have to do molecular testing. There needs to be multi-disciplinary review. There needs to be intensive surveillance, and you need to have rapid access to salvage surgery. Where is that infrastructure? In this country, it's mostly in academic centers. I think about the panel we had at ASCO GI, which was fantastic. And as we were having the conversation, you know, we set it up as a debate. So folks were debating either pro-surveillance or pro-surgery. But both groups, both people, were presenting outcomes based on their centers. And it was folks who were fantastic. Dr. Molena, for example, from Memorial Sloan Kettering was talking about their outcomes in esophagectomies [during our session at GI26], but they do hundreds of these cases there per year. What's the reality in this country? 70% to 80% to 90%, depending on which data you look at, of the gastrectomies in the United States occur at low-volume hospitals. Most of the patients at those hospitals are disproportionately uninsured or on government insurance, have lower income and from racial and ethnic minority groups. So if we diffuse organ preservations without the system to support it, we're going to create a two-tiered system of care where whether you have the ability to preserve your organs, to preserve bodily integrity, depends on where you live and where you're treated. The other piece of this is the biomarker testing gap. One of the things that, as you pointed out at the beginning, that's really exciting is for MSI-high tumors. Those are the patients that are most likely to benefit from immunotherapy-based organ preservation. But here's the problem. If the patient isn't tested at time of initial diagnosis before they ever see me as a surgeon, the door to organ preservation is closed before it's ever open. And testing access remains very inconsistent across academic networks. And then there's the financial toxicity piece where, for gastrectomy, pancreatectomy, I do peritoneal malignancies, more than half of those patients experience significant financial toxicity related to their cancer treatment. We're now proposing adding at least two years, that's the preliminary information, right? It's probably going to be longer. At least a couple of years of surveillance visits, repeated endoscopies, immunotherapy costs. How are we going to support patients through that? We're going to have to think about setting up navigation support, geographic solutions, what financial counseling looks like. My patient for clinic yesterday was driving to see me, and they were talking about how they were sliding because it was snowing. And they were sliding for the entire three-hour drive down here. Are we going to tell people like that that they need to drive down to, right, I work at a high-volume center, they're going to need to come here every three months, come rain or snow, to get scoped as opposed to the one-time having a surgery and not needing to have the scopes as frequently? My concern, like I said, I'm an optimist, I think it is going to work. I think we're going to figure out how to make it work. I'm worried about whether when we deploy it, we widen the already existing disparities. Dr. Pedro Barata: Gotcha, and that's a fantastic summary. And as I'm thinking also of what we've been talking in other solid tumors, which one of the following do you think is going to evolve first? So we are starting to use more MRD-based assays, which are based on blood test, whether it's a tumor-informed ctDNA or non-informed. We are also trying to get around or trying to get more information response to systemic therapies out of RNA-seq through gene expression signatures, or development of novel therapeutics which also can help you there. Which one of these areas you think you're going to help this SANO-like approach move forward, or you actually think it's actually all of the above, which makes it even more complicated perhaps? Dr. Ugwuji Maduekwe: I think it's going to be all of the above for a couple of reasons. I would say if I had to pick just one right now, I think ctDNA is probably the most promising and potentially the missing piece that can help us close the gap between clinical and pathologic response. If you achieve clinical complete response and your ctDNA is negative, so you have clinical and molecular evidence of clearance, maybe that's a low-risk patient for surveillance. If you have clinical complete response but your ctDNA remains positive, I would say you have occult molecular disease and we probably need intensified therapy, closer monitoring, not observation. I think the INFINITY trial is already incorporating ctDNA into its algorithm, so we'll know. I don't think we're at the point where it alone can drive surgical decisions. I think it's going to be a good complement to clinical response evaluation, not a replacement. The issue of where I think it's probably going to be multi-dimensional is the evidence base: who are we testing? Like, what is the diversity, what is the ancestral diversity of these databases that we're using for all of these tests? How do we know that ctDNA levels and RNA-seq expression arrays are the same across different ancestral groups, across different disease types? So I think it's probably going to be an amalgam and we're going to have to figure out some sort of algorithm to help us define it based on the patient characteristics. Like, I think it's probably different, some of this stuff is going to be a little bit different depending on where in the stomach the cancer is. And it's going to be a little bit more difficult to figure out if you have a complete clinical response in the antrum and closer to the pylorus, for example. That might be a little bit more difficult. So maybe the threshold for defining what a clinical complete response needs to be is higher because the therapeutic approach there is not quite as onerous as for something at the GE-junction. Dr. Pedro Barata: Wonderful. And I'm sure AI, whether it's digitization of the pathology from the biopsies and putting all this together, probably might play a role as well in the future.  Dr. Maduekwe, it's been fantastic. Thank you so much for sharing your insights with us and also congrats again for the really well-done review published.  For our listeners, thank you for staying with us. Thank you for your time. We will post a link to this fantastic article we discussed today in the transcript of this episode. And of course, please join us again next month on the By the Book Podcast for more insights on key advances and innovations that are shaping modern oncology. Thank you, everyone. Dr. Ugwuji Maduekwe: Thank you. Thank you for having me. Watch the ASCO GI26 session: Organ Preservation for Gastroesophageal and Gastric Cancers: Ready for Primetime? Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Follow today's speakers:          Dr. Pedro Barata   @PBarataMD    Dr. Ugwuji Maduekwe @umaduekwemd Follow ASCO on social media:          @ASCO on X (formerly Twitter)          ASCO on Bluesky         ASCO on Facebook          ASCO on LinkedIn          Disclosures:       Dr. Pedro Barata:   Stock and Other Ownership Interests: Luminate Medical   Honoraria: UroToday   Consulting or Advisory Role: Bayer, BMS, Pfizer, EMD Serono, Eisai, Caris Life Sciences, AstraZeneca, Exelixis, AVEO, Merck, Ipson, Astellas Medivation, Novartis, Dendreon   Speakers' Bureau: AstraZeneca, Merck, Caris Life Sciences, Bayer, Pfizer/Astellas   Research Funding (Inst.): Exelixis, Blue Earth, AVEO, Pfizer, Merck    Dr. Ugwuji Maduekwe: Leadership: Medica Health Research Funding: Cigna    

Performance and Works used with permission from the artist and venue. Mixing jazz, blues and funk with a healthy dose of the Hammond B3, the Pittsburgh based Norside produces a sound best described as Rust Belt Funk. Whether they're playing alongside contemporaries such as The New Mastersounds and Bar Kays, or pushing boundaries with the Steeltown Horns, Norside embodies the commitment to giving the Hammond B3 room to breathe and pushing musical boundaries. For this performance, they're joined by pre-eminent Northeast Ohio trumpeter Tommy Lehman. By this point in the program, Tommy needs no introduction but he travels extensively both as a member of Alla Boara and The Admirables and as the leader of multiple groups under his own name. Featuring Tommy Lehman on Trumpet, Skip Sanders on the Hammond B3, Steve Ippolito on Drums and Glenn Strother on Guitar, and from a March 13th, 2025 performance, it's Norside featuring Tommy Lehman…Live at the Bop Stop.

Was wäre, wenn nicht dein Alter, sondern dein Mikrobiom darüber entscheidet, wie lange du gesund bleibst? In dieser Folge der Flowgrade Show spreche ich mit Prof. Dr. Michaela Axt-Gadermann über eines der zentralen Themen für Gesundheit, Energie und Langlebigkeit: das Mikrobiom.Michaela gehört zu den führenden Expertinnen im deutschsprachigen Raum, wenn es um Darmgesundheit, Ernährung, Fasten und Prävention geht. Als Professorin, Ärztin, Forscherin und Autorin verbindet sie wissenschaftliche Tiefe mit klaren, alltagstauglichen Empfehlungen.Wir sprechen darüber, warum das Mikrobiom weit mehr ist als nur ein Verdauungsthema und wie stark es Entzündungen, Alterungsprozesse, Stoffwechsel, Immunsystem und sogar unsere geistige Leistungsfähigkeit beeinflusst. Ein besonderer Fokus liegt auf mikrobiomfreundlichem Fasten, der Rolle von Ballaststoffen, Vielfalt in der Ernährung und der Frage, warum Kaffee sogar positive Effekte auf Darm und Langlebigkeit haben kann.Viel Spaß beim Zuhören!Go for FLOW

Organ meats were once a valued staple in traditional diets, prized for their nutrient density and role in human health. Chef James Barry explains how they fell out of favor, why they matter more now than ever, and practical ways to bring them back into modern eating. He gives simple methods for using organ meats more regularly and helping you and your family over any initial aversion.Reference Linkshttps://informedchoicewa.substack.com/https://eatnakedkitchen.com/about/ICWA's Amazon affiliate link to the Pluck product line: https://amzn.to/49IyFv3. Disclaimer: Informed Choice Washington earns a commission at no extra cost to you when you shop for Pluck or anything else starting at the foregoing link.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Diners, Prions, and Drive-bys. Subscribe to our Patreon: patreon.com/trillbillyworkersparty

Welcome back to Frontier Scum! Free from their shackles and with rumours of swag stashed at the head of the train, the crew, joined by wily Pappy, progress through carriages crawling with guards... Pick up Frontier Scum here: https://gamesomnivorous.com/pages/frontier-scum Community Discord: https://discord.gg/z2NW53APFa Merch: https://mystery-quest-shop.fourthwall.com/en-gbp Members and Patrons get $7 off your order - that's like a free membership along with your stylish new adventuring attire! Become a member: https://www.youtube.com/channel/UCd5_xAWJ4yX6NZ5cZaccqPw/join Podcast: https://www.pickaxe.uk/mystery-quest Patreon link: https://www.patreon.com/MysteryQuest Follow the Cast: Tom: https://www.youtube.com/angorytom Smith: https://youtube.com/hatfilms Ross: https://www.youtube.com/@hatfilms Lydia: https://www.twitch.tv/squidgame Ravs: https://www.twitch.tv/ravs_ Editing & Sound Design: Oscar Henderson Thumbnail Art: Jack Bailey Learn more about your ad choices. Visit podcastchoices.com/adchoices

The idea for Liz Organ's thesis, "The Makings of a Good Birth," emerged from a moment of doubt about career paths and a deep frustration with how often women are ignored in the birthing process. What began as a casual discovery of the differences between doulas and midwives, and whether this could be a potential career path, turned into an interview-based anthropology project examining how birth is experienced, remembered, and shaped by culture, history, and power. Drawing on conversations with nine people, the thesis traces the evolution of American birthing culture, and explores different anthropological birth care models and individuals' personal experience with the medical system. In this episode, Liz also reflects on the challenges of researching a highly specialized topic without a dedicated advisor in medical anthropology, and on learning to let interviews guide the research. Tune in for reflections on centering people's stories, the rewards of interviewing family and friends, and why education, autonomy, and support are ultimately essential to a good birth. Reed community members can read Liz's thesis, “The Makings of a Good Birth” online in the Electronic Thesis Archive: https://rdc.reed.edu/i/b7703bac-4430-4f18-8dd1-81c531de2836 Explore more interviews with Reed College alumni on our website: reed.edu/burnyourdraft

SONGS in this podcast episode: M1 NUN KOMM DER HEIDEN HEILAND, JS BACH, 1714, BWV 61 (5:21) M2 TOCCATA & FUGUE in C MAJOR M.2 ADAGIO, 1710-1717, BWV 564 (4:20). M3 TWO-PART INVENTION in F MAJOR, JS BACH, 1720-1723 (0:40). M4 TWO-PART INVENTION in B-FLAT MAJOR, JS BACH, 1720-1723 (1:30) M5 TWO-PART INVENTION in D MINOR, JS BACH, 1720-1723, (0:55). M6 PRELUDE & FUGUE No. 5 “Le Clavier Bien Tempere” D-Major, JS BACH, 1722, BWV 850 (3:06). M7 JESU, JOY OF MAN'S DESIRING, JS BACH, 1723, BWV 147 (2:56) M8 CHORALE PRELUDE “WACHET AUF”, JS BACH, 1731, BWV 140 (3:37) PROGRAM NOTES Johann Sebastian Bach was a German composer and organist from the late Baroque period. He was born in Eisenach, in what is now central Germany. Bach lived from 1685 to 1750, The Baroque period was a 150-year period in music, dating from 1600 to 1750. Baroque music is Western Classical Music that followed the Renaissance period. Baroque music features drama, ornamentation, major and minor tones, and was presented in new ways – – like the Opera, Concerto, and Sonata, Baroque composers included BACH, HANDEL, VIVALDI. M9 AIR ON A G-STRING, JS BACH, 1730, BWV 1068 (2:27). Bach probably used the CLAVICHORD to compose most of his music. The Clavichord is small, lightweight and would not disturb people. The clavichord was very temperamental, because it required tuning before each play, just like a violin or guitar.  The keyboard instruments of the day were referred to as a general category: the “KLAVIER”….these included HARPSICHORD, CLAVICHORD, ORGAN and PIANOFORTE. Bach's favorite KLAVIER instrument was the LAUTENWERK or LUTE HARPSICHORD with animal gut strings.  The writing of music was in support of GOD and KINGS. Over time, Baroque Music evolved into what is today known as the modern Orchestra. Bach was a prolific composer, writing hundreds of pieces for solo instruments, particularly the organ. He also wrote pieces for orchestra and choir. Bach is MOST known for writing two or more  melodies or voices against each other. Also called point against point, or, Counterpoint. Bit Bucket A BWV catalog number is a unique identifier for musical works composed by Johann Sebastian Bach, standing for Bach-Werke-Verzeichnis (Bach Works Catalogue).  Today I will present 9 compositions, dating from 1710 to 1731, during the time Bach was about age 25 to 45. M1 TOCCATA & FUGUE in C MAJOR M.2 ADAGIO, 1710-1717, BWV 564 (4:20) Our first piece — TOCATA & FUGUE in C MAJOR , the 2nd movement (ADAGIO). an ORGAN COMPOSITION.     It is taken from a 1959 album of BACH ORGAN WORKS   . The movement is called ADAGIO ….which indicates “At Ease”, or “Slow and Stately”. Tempo is only 66-76 BPM. like the resting heart rate for many people. Great liner notes. HERE IS AN  excerpt from the liner notes on that album – – QUOTE “OUR BACH” said the obituary notice, “was the greatest organ and clavier player that ever lived”. Though it may seem strange to us now, Bach's genius during his life was recognized only as a master of the organ—not as a composer. It was actually over a hundred years after his death that his works revealed him as a unique and mighty composer. His reputation as an organist brought many invitations to test new organs and advise on the construction of them.  UNQUOTE As with most of his organ works , there is no autograph or manuscript score from Bach, his organ work manuscript copies are lost.  This song has a CONCERTO style and rhythm.  We will hear the 2nd or ADAGIO movement. . It is all very calm and beautiful and pastoral and serene…until Bach pulls out all the stops in the last minute of this ADAGIO movement. He is really rocking the walls and windows of that church. Without any further adieu, here is TOCATA & FUGUE in C MAJOR , the 2nd movement (ADAGIO). PLAY M2 SHOW PLUG – DON'T TOUCH THAT DIAL ! That was…M2 MUSICAL CREDIT: This Bach organ work  was recorded on the Luneburg Organ at St. Johanniskirche, in the town of Luneburg, in northern Germany, the organist is Professor Michael Schneider. This LP was produced and released on the SOMERSET label here in the US in 1959 The album title is BACH The Majesty of the Luneburger Organ. M2 NUN KOMM DER HEIDEN HEILAND, JS BACH, 1714, BWV 61 (5:21) Our next piece is the most famous church cantata written in 1714 for THE FIRST SUNDAY IN ADVENT. NUN KOMM DER HEIDEN HEILAND or in English “NOW COME, SAVIOR OF THE HEATHANS” A HEATHAN is a person with no religion, i.e., a PAGAN. In this chorale, Jesus is asked to …  come and save the pagans.  In 1714, Bach would have been 29 years of age. It turns out that this song goes back almost two centuries before BACH's time.  It's based on a LUTERAN CHORALE with words written by Martin Luther for the 1523 first Advent Sunday.  For centuries, this was the first hymn for the first Sunday of ADVENT.  What I will play next is an arrangement for as modern symphony orchestra (the Philadelphia Orchestra) and it is definitely JS BACH heard in those phrases. But it is a large orchestra – – Conducted by Leopold Stokowski.  This is an extremely restrained, demure, and understated interpretation of a Bach piece the most restrained I have ever heard. The recording you will hear next is performed by the Philadelphia Orchestra, with conductor   Leopold Stokowski. This recording is on a Vinyl LP titled THE SOUND OF GENIUS, produced by COLUMBIA MASTERWORKS, in 1960. It was one of many records that were shipped by mail to members of the Columbia Record Club. My parents were enthusiastic members. A new disc would arrive in the mail every month, such as this LP of classical music. Without further delay here is NOW COME, SAVIOR OF THE HEATHANS PLAY M1 SHOW PLUG – SHOW PLUG – DON'T TOUCH THAT DIAL ! ! That was…M1 NOW COME, SAVIOR OF THE HEATHANS” MUSICAL CREDIT: Arranger and Composer JS Bach, sometime between the years 1708-1717 Performance: Philadelphia Orchestra, conducted by Leopold Stokowski. Album: The Sound of Genius Limited Edition LP (1960) Members Only ! Label: Columbia Master Works BIT BUCKET This piece also is based on a song listed in the ZAHN Lutheran chorales catalog. ZAHN 1174 M3 TWO-PART INVENTION in F MAJOR, JS BACH, 1720-1723 (0:40) The next three pieces are called TWO PART INVENTIONS, composed by JS Bach around 1720   The inventions were composed for use in instruction of Bach's oldest son WILHELM FRIEDEMANN BACH who was 12 years old. Today, these inventions are introduced to music students in school grades 4-7. Learning the Two-Part Invention requires ROTE learning, practicing over and over until the two hands work completely independently of one another. The inventions teach, among other things, the use of COUNTERPOINT. Bach is MOST known for writing two melodies against each other. Also called point against point, or, Counterpoint. That is the feature of these inventions, in each one there are TWO PARTS, left and right hand parts. COUNTERPOINT is found mostly in Bach's FUGUES and in his INVENTIONS. Perhaps a brief demonstration is in order. Here is an excerpt from one of Bach's inventions. FIRST the right-hand part or first point – the melody SECOND the left-hand part or second point – the bass line LAST both parts played in counterpoint. In some of Bach works, the roles reverse, The left hand plays the first point – the melody And the right hand plays the second point – the bass line Could you do this by crossing hands on the keyboard – yes, but, the roles are reversed, so no cross-hand playing. I will now play  WENDY CARLOS's rendition of three BACH TWO-PART INVENTIONS from her 1969 recording titled “SWITCHED ON BACH” .. I will play all three, back-to-back. Each one is short – – average length ONE MINUTE EACH! PLAY M3 PLAY M4 PLAY M5 Credits: HOLD ON READING THE CREDITS UNTIL ALL THREE INVENTIONS ARE PLAYED M4 TWO-PART INVENTION in B-FLAT MAJOR, JS BACH, 1720-1723 (1:30) And now….. PLAY M4 SHOW PLUG – DON'T TOUCH THAT DIAL ! That was…M4 MUSICAL CREDIT: HOLD ON READING THE CREDITS UNTIL ALL THREE INVENTIONS ARE PLAYED M5 TWO-PART INVENTION in D MINOR, JS BACH, 1720-1723, (0:55) PLAY M5 SHOW PLUG – DON'T TOUCH THAT DIAL ! That was…M5 We heard three inventions – – Bach's 2-PART INVENTION in F MAJOR And the 2-PART INVENTION in B-FLAT MAJOR And the 2-PART INVENTION IN D MINOR Each invention is very different than the other. Not just a key change like the work title would suggest ! Bach stated that he wrote his inventions “to be models of composition” in other words, to enable the student to form ways of developing musical ideas and “acquire a strong taste of composition” Bach wrote the inventions, one for of the notes A to G and one for each minor and major key. Today these inventions are over 300 years old ! MUSICAL CREDIT: Composer JS Bach Estimated dates between 1720-1723 Performer – Wendy Carlos – early prototype Moog Synthesizer Arranger and Recording Engineer – Wendy Carlos on MOOG SYNTHESIZER in 1968. Record and label:  Switched-On Bach, Columbia/CBS BIT BUCKET M6 PRELUDE & FUGUE No. 5 “Le Clavier Bien Tempere” D-Major, JS BACH, 1722, BWV 850 (3:06) Next is Bach's “The Well-Tempered Clavier” written in 1722. He was 37. The title page to the Well-tempered Clavier song book reads : “The well-tempered Clavier, or Preludes and Fugues, through all the tones and semitones, both the [major] and [minor]. For the profit and use of the studious musical young…” Bach wrote these preludes and fugues in all keys in the chromatic scale … 12 major and 12 minor keys I have the version in D MAJOR. It's two sections – the prelude, and the fugue The Prelude is the introduction. LISTEN FOR the Stride Piano on the left hand !! It's a short 1:10. The Fugue is the second section. It's slower but with a more Bold left hand. Also short at 1:54. And now….PRELUDE & FUGUE No. 5 D-Major fromThe Well-Tempered Clavier PLAY M6 SHOW PLUG – DON'T TOUCH THAT DIAL !  That was…M6  PRELUDE & FUGUE No. 5 D-Major from The Well-Tempered Clavier MUSICAL CREDIT: Composer JS Bach and the autograph date is 1722 Pianist: Vasso Devetzi Label Festival Classique (1978) M7 JESU, JOY OF MAN'S DESIRING, JS BACH, 1723, BWV 147 (3:22) Our next song is Jesu, Joy of Man's Desiring This song was also composed by JS Bach in that same year of 1723 – – prolific at age 38. This was written for the Christian Feast of the Visitation- celebrated at the end of May in Western Christianity. The song is a Lutheran hymn. … a CANTATA and it has a CHORALE or chorus piece repeated twice within this cantata. There are many arrangements and versions because this song is one of Bach's most beautiful, well-known, and popular. The version we will hear next is arranged for SOLO PIANO. the pianist is Leon Fleisher. And Now, Here is Jesu, Joy of Man's Desiring – Bach       1723 PLAY M7 SHOW PLUG – DON'T TOUCH THAT DIAL ! That was…M7  Jesu, Joy of Man's Desiring MUSICAL CREDIT: JS Bach composer 1723 Performance: Leon Fleisher – Pianist    (courtesy of EPIC records) Album  THE SOUND OF GENIUS VOLUME 3   Label Columbia, 1962   (3:22) M8 CHORALE PRELUDE “WACHET AUF”, JS BACH, 1731, BWV 140 (3:37) Here is another Chorale recording titled Chorale Prelude VACKET OFF “Wachet Auf”, which translates to SLEEPERS, WAKE! This hymn was transcribed from a Lutheran hymn written in 1599 by written by Phillippe Nicolai. This Cantata is truly a work from the middle ages. In 1731, Bach took this hymn and created a 7-movement cantata, we will hear the first movement or PRELUDE”.  This cantata is sung in church on the Trinity Sunday. Today this piece is very popular piece in general…it is POPULAR CLASSICAL MUSIC.    J.S. Bach wrote 46 of these cantatas for church, in all. ODD FACT  about this song… it was performed only once by Bach, in Leipzig that year. And now the FIRST MOVEMENT  from  VACKET OFF …the Prelude PLAY M8 SHOW PLUG – DON'T TOUCH THAT DIAL ! that was M4    The Chorale Prelude “Wachet Auf”, also known as SLEEPERS, WAKE! Song credits M4 Credits: Hymn by Phillippe Nicolai in 1599 Transcribed by JS Bach in 1731 Performance: Wendy Carlos – on an early prototype Moog Synthesizer Wendy Carlos arranger and recording engineer Album:  Switched-On Bach Label: Columbia/CBS, 1968 M9 AIR ON A G-STRING, JS BACH, 1730, BWV 1068 (2:27) Our next AND LAST piece is from the Switched-On Bach album and s titled AIR ON A G-STRING. This title comes from Johann Sebastian Bach's Orchestral Suite No. 3 in D major,  written almost 300 years ago.   So what is the meaning of the song title Air on a G-String? Well, Bach composed this as an orchestral suite in 1730. 141 years later, August Wilhelm arranged the second movement for SOLO VIOLIN and he did something unique. He transposed the song down from D so that the entire piece could be played on one string of the violin, the G-String, which is the lowest register on that instrument. Here is an example of what this sounds like on the Violin G-String, thjs example with piano accompaniment—pardon the scratchy sound, is from an old 78 RPM disc in 1935. Play example  – Jacques Dumont (Violin) Bach Air On The G String with Andre Collard (piano) We went from Bach's orchestral piece, to Wilhelm's transcription for solo violin, to Wendy Carlos modern interpretation with her MOOG Synthesizer. Now here is Wendy Carlos' arrangement of Air on a G String, from her debut album, SWITCHED-ON BACH, in 1968. PLAY M9 SHOW PLUG – DON'T TOUCH THAT DIAL ! That was…M9  MUSICAL CREDIT: Composer JS Bach 1730 Performance Wendy Carlos on early prototype MOOG SYNTHESIZER Arranger and Recording Engineer: Wendy Carlos  Album:  Switched-On Bach Label: Columbia/CBS, 1968 END OF PROGRAM VV-031

In this episode of Ageless Future, Cade Archibald challenges the common view of muscle as merely cosmetic or mechanical, revealing instead that skeletal muscle functions as a powerful endocrine organ. He explains how contracting muscle releases signaling molecules called myokines that communicate with the brain, liver, immune system, and fat tissue—regulating metabolism, reducing inflammation, improving insulin sensitivity, and supporting cognitive health. Cade highlights why muscle is the body's largest glucose “sink,” making resistance training one of the most effective strategies for diabetes prevention and reversal. He also dives into the dangers of sarcopenia, emphasizing that muscle loss is not just weakness but a systemic breakdown that accelerates aging and increases vulnerability across every major body system. The episode closes with practical takeaways on preserving strength, building resilience, and treating muscle as one of the most essential foundations of longevity.RESOURCES:Book Comprehensive Labs: https://agelessfuture.com/longevity-labs/FREE copy of The Peptide Blueprint: https://agelessfuture.com/blueprintSign up for future Health Accelerator Challenges calls LIVE! https://us02web.zoom.us/webinar/register/WN_YZsiUMOzSyqcE8IinC5YEQ#/registrationBooks: https://www.amazon.com/Books-Regan-Archibald/s?rh=n%3A283155%2Cp_27%3ARegan%2BArchibaldArticles: https://medium.com/search?q=Regan+ArchibaldLIKE/FOLLOW/SUBSCRIBE:YouTube -https://www.youtube.com/@ReganArchibald / https://www.youtube.com/@Ageless.FutureLinkedIn: https://www.linkedin.com/in/regan-archibald-ab70b813Instagram: https://www.instagram.com/ageless.future/Facebook: https://www.facebook.com/AgelessFutureHealth/DISCLAIMER: This video is for educational purposes only and does not provide medical advice, diagnosis, or treatment.  Many of the molecules discussed in this video are research compounds and are not approved by the U.S. Food and Drug Administration (FDA) for any specific medical use, indication, or condition. They are mentioned only in the context of existing scientific literature and ongoing research and are not being recommended, prescribed, sold, or offered through this video. This content does not endorse or recommend any specific tests, products, procedures, or treatment protocols.References to our clinic are for general educational context only; investigational or non‑approved products are not available for direct ordering or prescribing based solely on viewing this content.  Do not start, stop, or change any medication, peptide, or supplement based on this video. All medical decisions must be made with a licensed prescribing clinician after a proper evaluation. No provider–patient relationship is created by viewing this content or contacting our clinic.  Regan Archibald is a Licensed Acupuncturist and longevity coach. He is not a medical doctor. Cade Archibald is COO and Co-Founder of Ageless Future, also not a medical doctor. All medical decisions, lab ordering, and prescribing in our clinic are performed only by our licensed medical team (MD, APRN, PA).  Viewers should follow the guidance of their own licensed clinicians and local health authorities regarding diagnosis and treatment decisions.

In this episode, Mike and Molly bridge the gap between the physics of waves and the biology of sensation. The MCAT loves the auditory system because it requires you to integrate knowledge from Physics (wave properties), Biology (structure of the ear and nervous system), and Psychology (signal detection).We take a "bird's ear view" of the auditory pathway, breaking it down into three critical stages:Mechanical Transmission: The outer and middle ear.Transduction: Converting movement into electricity in the inner ear.Neural Transmission: Sending the signal to the brain for interpretation.

Dr. Martin R. Prince discusses the findings of his study, "Automatically Measuring Kidney, Liver, and Cyst Volumes in Autosomal Dominant Polycystic Kidney Disease," with JASN Deputy Editor David H. Ellison.

SummaryIn this episode of the Gird Up Podcast, host Charlie Ungemach welcomes George Hogan, a student at Martin Luther College and an accomplished organist, to discuss the significance of liturgy and music in the Lutheran tradition. The conversation begins with George's background in theater and music, highlighting his passion for the organ and its role in worship. They explore the value of young people engaging in the arts, particularly theater, and how it fosters discipline and public speaking skills. As the discussion shifts towards church music, George emphasizes the importance of the organ in leading congregational singing, arguing that its unique sound and historical significance make it an irreplaceable instrument in worship settings.Chapters00:00 Introduction to the Gird Up Podcast03:22 Meet George Hogan: A Passion for Music07:21 The Value of Young People in the Arts12:19 George's Journey into Playing the Organ21:06 The Historical Significance of the Organ in Worship26:42 Why the Organ Should Remain in Modern Worship33:43 The Essence of Congregational Singing35:47 Historical Context of Worship Practices41:43 The Importance of Authenticity in Worship49:35 The Role of Music in Ministry01:12:23 George's Journey to the Ministry01:18:04 charlieungemach-outro (1).mp4George's Links:Luther Prep - https://www.lps.wels.net/Martin Luther College - https://mlc-wels.edu/Gird Up Links:https://youtube.com/@girdupministries4911?si=tbCa0SOiluVl8UFxhttps://www.instagram.com/girdup_be_a_man/https://www.girdupministries.com

Howdy Cowfolk and welcome to the acid punk weird west RPG, Frontier Scum, created by Karl Druid and the adventure 'Escape the Organ Rail'. Join a crusty band of outlaws aboard a notorious prison train bound for Fort Gullet where many good for nothings meet their end by the hangman's noose... Pick up Frontier Scum here: https://gamesomnivorous.com/pages/frontier-scum Community Discord: https://discord.gg/z2NW53APFa Merch: https://mystery-quest-shop.fourthwall.com/en-gbp Members and Patrons get $7 off your order - that's like a free membership along with your stylish new adventuring attire! Become a member: https://www.youtube.com/channel/UCd5_xAWJ4yX6NZ5cZaccqPw/join Podcast: https://www.pickaxe.uk/mystery-quest Patreon link: https://www.patreon.com/MysteryQuest Follow the Cast: Tom: https://www.youtube.com/angorytom Smith: https://youtube.com/hatfilms Ross: https://www.youtube.com/@hatfilms Lydia: https://www.twitch.tv/squidgame Ravs: https://www.twitch.tv/ravs_ Editing & Sound Design: Oscar Henderson Thumbnail Art: Jack Bailey Learn more about your ad choices. Visit podcastchoices.com/adchoices

Editor's Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from January 24-30, 2026.

The Mindset Shift That Separates Burnout from Breakthrough You've been told self-care is bubble baths and boundaries. But what if the real self-care is becoming the kind of person who doesn't need to recover from their own emotions every week? That's exactly what Dr. Gabrielle Lyon and I dig into in this episode. Dr. G is a board-certified physician and New York Times bestselling author who has worked with some of the most successful entrepreneurs in the world. And she says the ones who sustain success over time have one thing in common: they stay neutral. Big win? Neutral. Big problem? Neutral. It's just another Tuesday. We go way beyond nutrition and fitness in this conversation. We're talking about why emotional neutrality is one of the most underrated entrepreneurial skills, why discipline is actually the new self-care, and why your health quietly determines how far your business can go. Dr. G also shares how to catch yourself before old patterns start creeping back in and how to use your physical body as a tool for confidence and clarity. If you've ever felt like your emotions are running your business instead of you, this one's for you. HERE ARE THE 3 KEY TAKEAWAYS FROM THIS EPISODE: 1️⃣ Emotional Neutrality Is a Skill, Not a Personality Trait – The best entrepreneurs don't ride the highs and lows. They stay steady because as high as you let yourself go, that's how hard you'll crash. Neutrality isn't boring. It's sustainable. 2️⃣ Discipline Is the New Self-Care – Another episode or glass of wine isn't self-care if they pull you away from your standards. Real self-care is keeping promises to yourself, honoring your commitments, and building trust in your own word. 3️⃣ You Will Never Outgrow Your Health – Your business has a ceiling, and it's your body. You cannot outgrind your physiology. If you want to scale, your health has to come first. Not as a nice-to-have, but as the foundation everything else stands on. RESOURCES MENTIONED IN THIS EPISODE: The Forever Strong Playbook by Dr. Gabrielle Lyon (Order for book + bonuses + six-week challenge) Follow Dr. Gabrielle Lyon on Instagram House of Pamelyn by Pamelyn Rocco Body Health Essential Amino Acids Brooklyn Naked Nutrition Dried Beef CHAPTERS 00:00 - Just Another Tuesday: The Entrepreneur's Mindset 01:40 - Amy's Transformation Story 03:00 - The Start of Amy's Health Revolution 04:15 - Why Muscle Is the Organ of Longevity 05:20 - The One Trait of Ultra-Successful Entrepreneurs 07:40 - Emotional Highs Equal Emotional Lows 09:30 - Practicing Emotional Neutrality: A Real-Life Strategy 12:00 - Reframing Stress: Don't Avoid It, Add It 16:30 - Tend & Befriend: A Better Stress Response 19:00 - Discipline Is the New Self-Care 21:20 - How to Use Discernment to Fuel Focus 23:30 - Physical Discipline = Mental Confidence 25:30 - Using Your Body as a Tool for Mastery 28:10 - Standards vs. Goals: The Mindset Shift for High Achievers 30:00 - Protein Overload? Or Protein Revolution? 32:20 - You'll Never Outperform Your Health 34:00 - Behind the Scenes of the New Dietary Guidelines 36:55 - How Much Protein Should You Really Eat? 38:00 - Easy Protein Hacks for Busy Women 40:20 - How to Build a High-Protein Morning Routine 44:00 - Real-Life Meal Ideas: What Dr. Lyon Eats 48:15 - Muscle Builds Your Brain Power 50:00 - Know Yourself at Your Best 53:00 - Don't Go It Alone: Use Community for Accountability 55:15 - The Forever Strong Playbook: Your Tactical Guide 57:20 - Get the Bonuses + 6-Week Challenge 58:15 - Amy's Final Encouragement MORE FROM ME Follow me on Instagram @amyporterfield SUBSCRIBE & REVIEW If you loved this episode, please take a moment to subscribe and leave a review on Apple Podcasts! Your support helps us reach more entrepreneurs who need these insights.

Dr. Gabrielle Lyon explains why muscle—not body fat—is the real driver of metabolism, aging, and long-term health, and how most people are getting protein and carbs completely wrong.15 Daily Steps to Lose Weight and Prevent Disease PDF: https://bit.ly/46XTn8f - Get my FREE eBook now!Subscribe to The Genius Life on YouTube! - http://youtube.com/maxlugavereWatch my new documentary Little Empty Boxes - https://www.maxlugavere.com/filmThis episode is proudly sponsored by:Food waste is one of the biggest and most overlooked environmental problems—and most of it happens in our homes. Mill makes it effortless to do something about it, and you can try it risk-free for 90 days and get $75 off at http://mill.com/genius with code GENIUS.Fatty15 provides C15:0, a naturally occurring fatty acid found in full-fat dairy that may support cellular health and longevity—get 15% off at http://fatty15.com/MAX with code MAX!

We've long been told that health starts in the gut, but what if the key to ageing well begins with your muscles?This week I'm joined by Dr Gabrielle Lyon, physician, author of Forever Strong, and founder of the muscle-centric medicine movement. Gabrielle's work reframes how we think about muscle not just for strength or aesthetics, but as a powerful metabolic and endocrine organ that drives longevity, energy, and resilience.In this episode we discuss:

Welcome to Secrets of Organ Playing Podcast No. 763! Today Ausra and I will discuss our organ recitals at Notre Dame Cathedral in Paris. Hope you will enjoy it!Here you will find all my scores: https://www.sheetmusicplus.com/en/category/arrangeme/?q=Secrets+of+Organ+Playing&aff_id=454957Secrets of Organ Playing Mug: https://www.zazzle.co.uk/z/ywbhd071?rf=238366920809443329You can support this channel by becoming a member here: https://www.youtube.com/channel/UCO4K3_6QVJI_HlI5PCFQqtg/joinIf you like what I do, you can buy me some coffee: https://www.buymeacoffee.com/organduoPayPal: https://PayPal.Me/VPinkeviciusWe support Ukraine: https://www.blue-yellow.lt/enMy Hauptwerk setup: https://www.organduo.lt/tools.htmlTotal Organist - the most comprehensive organ training program online: https://www.organduo.lt/total-organistSecrets of Organ Playing - When You Practice, Miracles Happen! https://organduo.ltListen to my organ playing on Spotify: https://open.spotify.com/artist/0ckKPIvTWucoN3CZwGodCO?si=YWy7_0HqRvaZwBcovL-RKg#secretsoforganplaying #vidaspinkevicius #ausramotuzaite

Your butt is not about aesthetics. It is a longevity organ that directly impacts metabolism, brain optimization, resilience, and how long you stay strong as you age. In this episode, you'll learn why strength training and protein intake matter more than body fat percentage, how mitochondria drive human performance and recovery, and why building muscle protects your brain, stabilizes mood, and supports long-term longevity. This conversation reframes biohacking, anti-aging, and health from weight loss to muscle span, the length of time you live with strong, functional skeletal muscle. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Gabrielle Lyon, an accomplished physician and New York Times bestselling author of Forever Strong: A New, Science-Based Strategy for Aging Well, and author of the upcoming The Forever Strong Playbook, releasing January 27, 2026. Dr. Lyon pioneered the Muscle-Centric Medicine® approach, which places muscle at the center of disease prevention, metabolic health, and true vitality. She has trained elite athletes, military operatives, and public figures, while also living this philosophy at home as a mother of two with her husband, a retired Navy SEAL. Together, they break down why intermuscular fat may matter more than body fat percentage, how skeletal muscle drives insulin sensitivity and lowers inflammation, and why becoming physically stronger improves brain function and neuroplasticity. They explore protein needs across the lifespan, fasting, ketosis, carnivore-style nutrition, supplements, sleep optimization, and the real tradeoffs of GLP-1 drugs, including the risk of accelerated muscle loss if strength and protein are neglected. The conversation also covers mindset, hormesis, and why physical resilience creates emotional regulation and clearer decision-making in a world increasingly shaped by AI and convenience. This episode is essential listening for anyone serious about biohacking, hacking human performance, longevity, mitochondria, neuroplasticity, nootropics, metabolism, functional medicine, anti-aging strategies, supplements, and living Smarter Not Harder, ideally with a cup of Danger Coffee in hand. You'll Learn: • Why your glutes and skeletal muscle are critical drivers of longevity and brain health • Why intermuscular fat can matter more than body fat percentage for metabolic dysfunction • How strength training improves neuroplasticity, cognition, and emotional resilience • Why protein needs increase with age and why outdated limits can hold you back • What GLP-1 drugs get right, where they fail, and how to protect muscle span • Why progressive stimulus beats lifting heavy for long-term strength and injury prevention • How sleep optimization and recovery support mitochondria and human performance • How building muscle creates clarity, resilience, and better decision-making Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Thank you to our sponsors! Quantum Upgrade | Support your brain, energy, focus, sleep, and recovery with Quantum Upgrade, a 24/7 streaming quantum energy service designed to work continuously in the background. Try it free for 15 days with no credit card required: https://quantumupgrade.io/DAVE Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle. KillSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com and use code DAVE for 20% off. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: muscle longevity organ, glutes brain health, strength training longevity podcast, muscle span aging, intermuscular fat metabolism, IMAT insulin resistance, skeletal muscle brain function, neuroplasticity strength training, protein intake aging, high protein diet longevity, metabolism muscle health, mitochondria muscle brain, muscle centric medicine podcast, gabrielle lyon podcast, forever strong playbook, women strength training longevity, GLP-1 muscle loss, sarcopenia aging prevention, resistance training brain health, sleep optimization muscle recovery, fasting ketosis muscle health, carnivore diet muscle metabolism, functional medicine muscle health, biohacking strength longevity, human performance muscle, anti-aging strength training, supplements muscle recovery, progressive stimulus training, blood flow restriction training, muscle resilience mindset Resources: • Get Gabrielle's NEW book Forever Strong: https://drgabriellelyon.com/forever-strong/ • Gabrielle's Website: https://drgabriellelyon.com/ • Follow Gabrielle's Instagram: https://www.instagram.com/drgabriellelyon/ • Gabrielles Youtube: https://www.youtube.com/@DrGabrielleLyon • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Introduction 1:01 – The Playbook vs Workbook 3:47 – Protein & Metabolic Health 6:21 – Mindset & Negativity 7:20 – Histamines & Hot Flashes 10:49 – Women & Strength Training 13:40 – Connective Tissue & EDS 16:15 – Muscle Span & Aging 19:41 – Training for Kids 21:55 – Pain Cave & Discomfort 25:25 – Emotional Regulation 29:46 – Resilience & Dating 32:11 – Building Friction & Discernment 35:47 – Self-Denial vs Awareness 41:03 – Mitochondria & Energy 42:46 – Bigger Booty, Bigger Brain 44:52 – Body Fat vs IMAT 49:01 – Measuring Muscle Health 52:08 – GLP-1s & Muscle Loss 56:12 – Protein Absorption Myths 59:30 – mTOR & Protein 1:01:29 – Closing Thoughts See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Natalie Crawford sits down with physician and muscle-centric medicine expert Dr. Gabrielle Lyon to explore why skeletal muscle is a powerful driver of hormones, metabolism, fertility, and long-term health, and how women can begin to support it at any age. Key Topics: 1. Muscle as an Organ of Longevity - How skeletal muscle influences hormones, metabolism, inflammation, and aging - Why “muscle span” matters across childhood, reproductive years, and beyond - Rethinking muscle as essential biology rather than aesthetics 2. Fertility, Pregnancy, and Metabolic Health - How muscle relates to insulin resistance, embryo quality, and fertility outcomes - The role of muscle health before and during pregnancy - Why activity and resistance training are key in hormonally vulnerable seasons 3. Training and Nutrition Fundamentals - Practical ways women can start strength training at any level - The importance of stimulus, not perfection, for building and maintaining muscle - How protein intake and meal structure support muscle and body composition 4. Mindset, Stress, and Long-Term Resilience - How mindset can hold women back from building strength - Reframing stress, challenge, and discomfort in training and daily life - Focusing on what you can gain—in health, function, and confidence—over the long term Pre-order Dr. Crawford's debut book, The Fertility Formula, now! ⁠https://www.nataliecrawfordmd.com/book⁠ Website: https://drgabriellelyon.com/ Instagram: https://www.instagram.com/drgabriellelyon/ YouTube: https://www.youtube.com/@DrGabrielleLyon Order FOREVER STRONG: https://drgabriellelyon.com/forever-strong/ Order THE FOREVER STRONG PLAYBOOK: https://drgabriellelyon.com/playbook/ Want to receive my weekly newsletter? Sign up at ⁠⁠⁠⁠nataliecrawfordmd.com/newsletter⁠⁠⁠⁠ to receive updates, Q&A, special content, and freebies If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every Tuesday. Plus, be sure to follow along on Instagram ⁠⁠⁠⁠@nataliecrawfordmd,⁠⁠⁠⁠ check out Natalie's YouTube channel Natalie Crawford MD⁠⁠⁠⁠, and if you're interested in becoming a patient, check out ⁠⁠⁠⁠Fora Fertility. Join the Learn at Pinnacle app ⁠to earn FREE CE Credit for listening to this episode! This episode is brought to you by The Pinnacle Podcast Network! Learn more about Pinnacle at http://learnatpinnacle.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Order The Forever Strong PLAYBOOK: https://drgabriellelyon.com/playbook/Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this solo episode, Dr. Gabrielle Lyon shares the deeper mission behind The Forever Strong PLAYBOOK and the philosophy that has guided her work for decades.This conversation is not about trends, quick fixes, or aesthetics. It is about building strength as a lifelong responsibility and understanding why skeletal muscle is the foundation of health, resilience, and independence across the lifespan.Dr. Lyon introduces the Forever Strong ethos and walks through the four foundational pillars that support a strong life: how to think, how to eat, how to move, and how to recover. She explains why information alone does not change behavior and why clarity, discernment, and disciplined action are the true drivers of lasting health.Throughout the episode, Dr. Lyon challenges conventional narratives around aging, nutrition, exercise, and recovery. She reframes longevity through the lens of muscle span, the length of time a person lives with healthy, functional skeletal muscle, and explains how physical strength supports metabolic health, emotional regulation, and cognitive resilience.This episode is an invitation to step out of confusion and into a clear framework for living with intention. Strength is not something we inherit. It is something we build, choice by choice, day by day.Thank you to our sponsors: Timeline - Get 35% off a Mitopure subscription at https://www.timeline.com/drlyonFour Sigmatic - Go to http://foursigmatic.com/gabrielle for a free bag of their dark roast ground coffee (just pay for shipping & handling).Find Dr. Gabrielle Lyon at: Instagram:@drgabriellelyonTikTok: @drgabriellelyonFacebook: facebook.com/doctorgabriellelyonYouTube: youtube.com/@DrGabrielleLyonX (Twitter): x.com/drgabriellelyonTimestamps: 00:00 – The Forever Strong Mission01:15 – The Forever Strong Ethos06:00 – Muscle as the Organ of Longevity09:40 – How to Think10:24 – Using the Body to Train the Mind19:41 – Discernment and Mental Strength28:43 – How to Eat38:10 – Protein, Carbohydrates, and Metabolic Health48:04 – Food Quality and Nutrient Density51:30 – How to Move57:59 – Training for Strength and Sustainability1:06:39 – How to Recover1:12:00 – Forever StrongDisclaimers: This episode includes paid sponsorships.The Dr. Gabrielle Lyon Podcast and YouTube are for general information purposes only and do not constitute the practice of medicine, nursing, or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast, YouTube, or materials linked

Today, I'm joined by the remarkable Dr. Gabrielle Lyon, a pioneer in redefining the longevity conversation by making muscle health—not weight—the centerpiece of aging well. With a background in geriatrics and nutritional sciences, she illuminates why the quality of your muscle tissue is a far more powerful predictor of health than any number on the scale. Her perspective challenges the notion of a "healthy sedentary person" and reveals the major role of intramuscular fat in metabolic dysfunction.   Episode Timestamps: Introduction, podcast focus, and welcoming Dr. Gabrielle Lyon ... 00:00:00 Muscle's impact on brain health, inflammation, and healthy aging ... 00:01:03 Dr. Lyon's childhood, grit, and self-discipline ... 00:04:33 Mentorship and protein science under Dr. Donald Lehman ... 00:07:05 Muscle as the overlooked metabolic organ ... 00:08:45 Why intramuscular fat matters more than body weight ... 00:10:06 Plant vs. animal protein for muscle health ... 00:13:29 Muscle as an endocrine organ and cognition ... 00:16:21 Future of muscle science: anabolics, imaging, and technology ... 00:18:22 GLP-1s, sarcopenic obesity, and muscle-first protocol ... 00:46:45 Sarcopenia, aging, and the importance of early training ... 01:04:35 Building lifelong resilience—mental and physical ... 01:08:31 Predictions: anabolics, muscle testing, and assessment ... 01:12:17 "Strength is a responsibility, not a luxury" ... 01:13:53   Our Amazing Sponsors: Cozy Earth – Thoughtfully designed bedding and bath essentials that turn your home into a calm, elevated retreat and actually hold up wash after wash. Give your space a reset at cozyearth.com with code LONGEVITY for up to 20% off, and don't forget to mention this podcast in the post-purchase survey.   Ozlo - use smart sound engineering and sleep detection to help you stay in deeper, more stable sleep all night. Create your ideal sleep environment anywhere: go to ozlosleep.com/nat and use code NAT to get $75 off. Tranq Dart by Wizard Sciences - a multi-pathway sleep support from Wizard Sciences. It's not a knockout pill; it's a gentle nudge toward that wind-down zone. I take it about 30 minutes before bed, and it helps my body and brain sync up for sleep. Visit wizardsciences.com and use code NAT15 for 15% off. Sleep smarter, not harder.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

One of the only pig kidney recipients in the world just made medical history, again. Cursive is making a comeback nationwide, but these middle schoolers were ahead of the curve. A group of Buddhist monks are walking across the US with an inspiring message. We tell you about a TikTok trend that's encouraging to cut down on screen time. Plus, as Hollywood spotlights table tennis, an American phenom shares how the sport changed her life.  Sign up for the CNN 5 Good Things newsletter here.  Host/Producer: Krista Bo Polanco  Producer: Eryn Mathewson Showrunner: Faiz Jamil  Senior Producer: Felicia Patinkin  Editorial Support: Kameryn Griesser, Melani Bonilla, and Andy Buck Learn more about your ad choices. Visit podcastchoices.com/adchoices

One of the only pig kidney recipients in the world just made medical history, again. Cursive is making a comeback nationwide, but these middle schoolers were ahead of the curve. A group of Buddhist monks are walking across the US with an inspiring message. We tell you about a TikTok trend that's encouraging to cut down on screen time. Plus, as Hollywood spotlights table tennis, an American phenom shares how the sport changed her life.  Sign up for the CNN 5 Good Things newsletter here.  Host/Producer: Krista Bo Polanco  Producer: Eryn Mathewson  Showrunner: Faiz Jamil  Senior Producer: Felicia Patinkin  Editorial Support: Kameryn Griesser, Melani Bonilla, and Andy Buck  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Die 282. Ausgabe fällt wieder in unsere Rubrik Schafft Wissen. Ausgangspunkt ist die Brandkatastrophe in Crans-Montana. Unser Co-Host Matthias Farlik hat sich als Molekularbiologe und Immunologe im Laufe seiner Karriere intensiv mit der menschlichen Haut auseinandergesetzt. Sie ist unser größtes Organ, besteht aus drei Hauptschichten und erfüllt eine Vielzahl lebenswichtiger Funktionen. Wird die Haut durch Verbrennungen großflächig zerstört, sinkt die Überlebensrate dramatisch. Und die, die überleben, haben einen langen Leidensweg vor sich. Was genau passiert im Körper nach schweren Verbrennungen? Wie kann Opfern geholfen werden - und wo geht die Forschung hin? Im Studio: Edith Meinhart, Matthias Farlik und Michael Nikbakhsh // Die Dunkelkammer ist ein Stück Pressefreiheit.   Unabhängigen Journalismus kannst Du mit einer Mitgliedschaft via Steady   unterstützen https://steady.page/de/die-dunkelkammer/about   Vielen Dank! Michael Nikbakhsh im Namen des Dunkelkammer-Teams 

Add these 7 zero-sugar foods to your diet today to counter the effects of sugar. These healthy foods will not spike insulin and can help stabilize your blood sugar. Discover the healthiest foods with no sugar and no carbs!

Join Dr. Aimee and leading endometriosis researcher Dr. Kevin Osteen from Vanderbilt University as they explore the hidden connection between environmental toxicants and reproductive health. Discover how dioxin exposure can impact fertility across multiple generations—and what you can do about it. In This Episode: • How environmental toxicants like dioxin affect endometriosis and fertility • The science behind transgenerational health risks (your grandmother's exposure may affect you) • Organ-on-a-chip technology revolutionizing reproductive research • Why both maternal AND paternal toxicant history matters for pregnancy outcomes • Anti-inflammatory diet strategies to protect your fertility • Practical tips to reduce toxicant exposure in daily life Perfect for: Women with endometriosis, couples planning pregnancy, IVF patients, and anyone concerned about environmental impacts on reproductive health. About Dr. Kevin Osteen: Professor of OB/GYN at Vanderbilt University School of Medicine, Director of the International Endometriosis Association Research Program, pioneering researcher in environmental endocrine disruptors and fertility. Read the full show notes on Dr. Aimee's website Learn more about Dr. Osteen here. Do you have questions about IVF? Click here to join Dr. Aimee for The IVF Class. The next live class call is on Monday, February 9, 2026, at 4 pm PST, where Dr. Aimee will explain IVF and Egg Freezing, and there will be time to ask her your questions live on Zoom. Other ways to follow Dr. Aimee: Visit my YouTube channel for more fertility tipsSubscribe to the newsletter to get updatesJoin The Egg Whisperer SchoolRequest a Consultation with Dr. Aimee  Dr. Aimee Eyvazzadeh is one of America's most well‑known fertility doctors. Her success rate at baby‑making gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org. Topics: Endometriosis | Reproductive Health | Environmental Toxicants | Dioxin | Fertility | Epigenetics | Transgenerational Health | IVF | Preterm Birth | Anti-Inflammatory Diet | Progesterone Resistance | Organ-on-a-Chip | Women's Health | Pregnancy Planning

Wie oft hat man schon von der Leberzirrhose gehört, aber trotzdem weiss man als Laie gar nicht so genau, was das ist. Anhaltende Entzündungen schädigen die Leber, was zu einer Vernarbung derselben führt. Schlussendlich verliert die Leber ihre Funktionsfähigkeit. Die Leber ist ein regenerationsfähiges Organ. Allerdings bleiben die Narben, sagt Yves Borbély. Er ist Gastroenterologe am Berner Inselspital. Übergewicht, ein erhöhter Blutzucker und allen voran der Alkohol setzen der Leber zu, bis es eben zu einer Leberzirrhose kommen kann. Deshalb ist damit einhergehend stets eine Änderung der Lebensgewohnheiten geboten.

This episode of TTCL will feature an interview with Luis Santiago from NFH on La Mega. This monthly interview will inform the Spanish Community about Network For Hope and the incredible miracles that happen with Organ, Tissue, and Eye Donation. Resources: https://getoffthelist.org/ https://www.networkforhope.org/ https://www.networkforhope.org/about-us/ https://www.facebook.com/NetworkForHopeOPO https://aopo.org/ RegisterMe.org/NetworkforHope

In this episode, Corey LeBleu, a veteran penetration tester, shares a raw and intense story from his early days in offensive security. Corey walks through a social engineering engagement that took a sharp turn, from being closely watched by a security guard to receiving the call that changed everything. What followed was a confrontation with authority, handcuffs, and a moment that forced him to confront the legal and emotional consequences of impersonation.Through honest storytelling, Corey reflects on the pressure of physical security testing, the thin line between authorization and trouble, and the lessons he carried forward in his career. This episode serves as a cautionary tale about understanding boundaries, respecting authority, and the unseen risks behind revealing what's hidden.00:00 Introduction to Corey LeBleu and His Journey03:34 Corey's Early Career and Learning Path06:34 The Role of Mentorship in Pen Testing09:19 Experiences in Social Engineering and Physical Pen Testing12:22 The Handcuff Incident: A Lesson in Risk15:12 Transitioning to Web Application Pen Testing18:01 The Evolution of Pen Testing Practices20:48 The Impact of AI on Pen Testing23:42 The Future of Pen Testing and Learning for Beginners26:28 Navigating Active Directory and Pen Testing Tools27:35 Essential Training for Web App Pen Testing30:34 Advice for Aspiring Pen Testers32:30 Exploring AI and Learning Resources37:05 Personal Interests and Hobbies39:17 Living in Austin and Local Music SceneSYMLINKS[LinkedIn] – https://www.linkedin.com/in/coreylebleu/Primary platform Corey recommends for connecting with him professionally.[Relic Security] – https://www.relixsecurity.com/Cybersecurity consulting firm founded and run by Corey LeBleu, focused primarily on web application penetration testing and offensive security work.[PortSwigger Academy] – https://portswigger.net/web-securityA free and advanced online training platform for web application security, created by the makers of Burp Suite. Recommended by Corey as one of the best learning resources for modern web app pentesting.[Burp Suite] – https://portswigger.net/burpA widely used web application security testing tool. Corey emphasizes learning Burp Suite as a core skill for anyone entering web app penetration testing.[OWASP Juice Shop] – https://owasp.org/www-project-juice-shop/An intentionally vulnerable web application created by OWASP for learning and practicing web security testing.[OWASP – Open Web Application Security Project] – https://owasp.orgA global nonprofit organization focused on improving software security. Corey previously ran an OWASP project and references OWASP tools and resources throughout his career.[SANS Institute] – https://www.sans.orgA major cybersecurity training and certification organization, referenced in relation to early penetration testing education and the high cost of formal training.[Hack The Box] – https://www.hackthebox.comAn online platform for practicing penetration testing skills in simulated environments.[PromptFoo] – https://promptfoo.devA tool for testing, evaluating, and securing LLM prompts. Mentioned in the context of prompt injection and AI security experimentation.[PyTorch] – https://pytorch.orgAn open-source machine learning framework widely used for deep learning and AI research. Corey mentions it as part of his learning path for understanding how LLMs work.[Hugging Face] – https://huggingface.coAn AI platform providing open-source models, datasets, and tools for machine learning and LLM experimentation.

We recount dumb things our friends believe, Jenny gives us some skills that could change our lives, and more!See omnystudio.com/listener for privacy information.

This week, Donald Macleod explores the life and music of Aaron Copland, one of the most distinctive voices in 20th-century American music. From his Brooklyn childhood and formative studies in Paris to his return home with bold new ideas, Copland's career charts a path through modernism, jazz, and the search for an unmistakably American sound. We hear music that captures the spirit of a nation – from Billy the Kid and Lincoln Portrait to his Fanfare for the Common Man, before he made the move from composer to conductor. Music featured includes: 4 Dance Episodes from Rodeo: iv. Hoe Down Two Preludes for violin and piano Four Early Songs: i. Night; ii. A Summer Vacation; iii. My Heart is in the East; iv. Alone Four Motets: iii. Have Mercy on Us, O My Lord Three Moods: i. Embittered; ii. Wistful; iii. Jazzy Symphony for Organ and Orchestra: ii. Scherzo; iii. Finale: Lento The Cat and the Mouse Old Poem; Pastorale Music for the Theater: i. Prologue; ii. Dance Piano Concerto Vitebsk (trio for violin, cello and piano) Hear Ye! Hear Ye! – ballet in one act: Scene i (Prelude) Piano Variations Short Symphony (Symphony No. 2): i. Incisivo; ii. Espressivo; iii. Presto e ritmico El Salón México Billy the Kid Suite: i. Introduction: The Open Prairie; ii. Street in a Frontier Town; iii. Mexican Dance and Finale Letter from Home Appalachian Spring Suite: v. Solo Dance; vi. Meno mosso; vii. Variation on a Shaker Hymn Clarinet Concerto Lincoln Portrait Fanfare for the Common Man Two Pieces for String Quartet: No. 2. Allegro Moderato Piano Quartet: iii. Non troppo lento Music for a Great City: i. SkylinePresented by Donald Macleod Produced by Elizabeth Ajao for BBC Audio Wales & West For full track listings, including artist and recording details, and to listen to the pieces featured in full (for 30 days after broadcast) head to the series page for Aaron Copland (1900-1990): https://www.bbc.co.uk/programmes/m002p75g And you can delve into the A-Z of all the composers we've featured on Composer of the Week here: http://www.bbc.co.uk/programmes/articles/3cjHdZlXwL7W41XGB77X3S0/composers-a-to-z

Fins, Fur and Feathers: A Unique Spread of Rabies Common Causes of Cattle Abortions in 2025 Less Dairies, Bigger Herds   00:01:05 – Fins, Fur and Feathers: A Unique Spread of Rabies: Drew Ricketts and Joe Gerken from K-State begin today's show with part of a Fins, Fur and Feathers podcast episode where they conversed about a rare case of rabies. Fins, Fur, and Feathers wildlife.k-state.edu   00:12:05 – Common Causes of Cattle Abortions in 2025: K-State veterinarian Gregg Hanzlicek keeps the show rolling as he breaks down the common causes of abortions in cattle from his 2025 lab data. ksvdl.org 866-512-5650 ksvdl YouTube   00:23:05 – Less Dairies, Bigger Herds: The Kansas dairy industry is showing sustained growth in terms of milk production. However, K-State dairy specialist Mike Brouk ends the show saying dairy herds increased in size in 2025, but the total number of dairy farms decreased — something he expects to continue in 2026.      Send comments, questions or requests for copies of past programs to ksrenews@ksu.edu.   Agriculture Today is a daily program featuring Kansas State University agricultural specialists and other experts examining ag issues facing Kansas and the nation. It is hosted by Shelby Varner and distributed to radio stations throughout Kansas and as a daily podcast.   K‑State Extension is a short name for the Kansas State University Cooperative Extension Service, a program designed to generate and distribute useful knowledge for the well‑being of Kansans. Supported by county, state, federal and private funds, the program has county Extension offices statewide. Its headquarters is on the K‑State campus in Manhattan. For more information, visit www.ksre.ksu.edu. K-State Extension is an equal opportunity provider and employer.

Welcome to the Speaking Podcast. Guest Maria Garcia shares her powerful story of resilience after a massive stroke at 25 and the long recovery that followed. Maria discusses relearning basic functions, writing her memoir Breaking Into Delight, and discovering a transformative nutritional approach years later that significantly improved her recovery. She now coaches others to reset their relationship with food and reclaim their health and purpose.   --- All Episodes can be found at ⁠⁠https://www.podpage.com/speaking-podcast/⁠   All about Roy / Brain Gym & Virtual Assistants at ⁠⁠https://roycoughlan.com/⁠⁠   #mariagarcia #speaker #wildfit    Bio of Maria Garcia Maria Garcia is a powerful example of resilience and self-discovery. After earning double majors in Finance and International Business, she initially made her mark in the corporate world. But her path took an unexpected turn when a massive stroke altered her life forever. Through sheer determination and a long, challenging recovery, Maria emerged stronger, with a deeper sense of purpose.Maria channeled her transformative journey into her memoir, Breaking Into the Light: A Journey of Self-Discovery and Transformation, sharing her journey and the lessons learned along the way. Almost a decade after the book's release, she discovered a groundbreaking nutritional methodology, which played a pivotal role in her continued recovery and personal transformation.Today, Maria is a passionate coach, committed to helping others navigate their own journeys of recovery and transformation. She specializes in guiding individuals to reset their relationship with food, unlocking profound shifts in their overall life experience. What we Discussed:   00:00 Intro   00:20 Who is Maria garcia   02:10 How she got ill   03:30 Organ donation company speaking to her family   04:40 What was going on in her head when she could not move for 2 weeks   05:30 Her 1st movement in her body   07:00 Getting scared when sh saw the Nurse walk in   07:50 Dr's do not always get it right   09:25 The Next stage after the hospital   10:30 Birth Control pills can be dangerous   12:30 When she went home in a wheelchair and diapers   14:15 What was going on in her head at this stage   15:20 How she got out of the wheel chair   16:10 How Yoga helped a lot   17:30 Investigating different ways to heal   18:53 How her family kept Hope Alive   20:05 Getting into Personal Development   23:52 The importance of rereading a good book   26:00 When she found an ad about Nutrition   28:25 Developing a career on Nutrition   30:13 How the Food has been made toxic   30:30 The Wheel of Health   32:30 People lost touch with Nature   33:23 How to find healthy food   35:00 The Food Pyramid was inverted   35:40 Listen to your body   36:50 Pringles are not healthy or safe   38:30 Pork and Chicken are not the best meat to eat   39:45 What has she seen of illnesses being cured   41:30 How I cured my back pain   43:30 How they create confusion with food   46:10 Her Book on the journey   48:00 How she got onto the speaking stage   49:40 Tapping into her intuition   55:00 Sometime the vitamin pills are not natural   How to Contact ⁠www.genuinelymaria.com⁠ ⁠https://www.linkedin.com/in/maria-garcia-7273a8230/⁠ ⁠https://www.facebook.com/profile.php?id=61565412543083 ⁠ ⁠https://www.instagram.com/genuinelymaria.wf/ ⁠ ------------------ All about Roy / Brain Gym & Virtual Assistants at ⁠⁠https://roycoughlan.com/⁠⁠  

Welcome to the Speaking Podcast. Guest Maria Garcia shares her powerful story of resilience after a massive stroke at 25 and the long recovery that followed.Maria discusses relearning basic functions, writing her memoir Breaking Into Delight, and discovering a transformative nutritional approach years later that significantly improved her recovery. She now coaches others to reset their relationship with food and reclaim their health and purpose.---All Episodes can be found at ⁠https://www.podpage.com/speaking-podcast/ All about Roy / Brain Gym & Virtual Assistants at ⁠https://roycoughlan.com/⁠ #mariagarcia #speaker #wildfit  Bio of Maria GarciaMaria Garcia is a powerful example of resilience and self-discovery. After earning double majors in Finance and International Business, she initially made her mark in the corporate world. But her path took an unexpected turn when a massive stroke altered her life forever. Through sheer determination and a long, challenging recovery, Maria emerged stronger, with a deeper sense of purpose.Maria channeled her transformative journey into her memoir, Breaking Into the Light: A Journey of Self-Discovery and Transformation, sharing her journey and the lessons learned along the way. Almost a decade after the book's release, she discovered a groundbreaking nutritional methodology, which played a pivotal role in her continued recovery and personal transformation.Today, Maria is a passionate coach, committed to helping others navigate their own journeys of recovery and transformation. She specializes in guiding individuals to reset their relationship with food, unlocking profound shifts in their overall life experience. What we Discussed: 00:00 Intro 00:20 Who is Maria garcia 02:10 How she got ill03:30 Organ donation company speaking to her family04:40 What was going on in her head when she could not move for 2 weeks05:30 Her 1st movement in her body07:00 Getting scared when sh saw the Nurse walk in07:50 Dr's do not always get it right09:25 The Next stage after the hospital10:30 Birth Control pills can be dangerous12:30 When she went home in a wheelchair and diapers14:15 What was going on in her head at this stage15:20 How she got out of the wheel chair16:10 How Yoga helped a lot17:30 Investigating different ways to heal18:53 How her family kept Hope Alive20:05 Getting into Personal Development23:52 The importance of rereading a good book26:00 When she found an ad about Nutrition28:25 Developing a career on Nutrition30:13 How the Food has been made toxic30:30 The Wheel of Health32:30 People lost touch with Nature33:23 How to find healthy food35:00 The Food Pyramid was inverted35:40 Listen to your body36:50 Pringles are not healthy or safe38:30 Pork and Chicken are not the best meat to eat39:45 What has she seen of illnesses being cured41:30 How I cured my back pain43:30 How they create confusion with food46:10 Her Book on the journey48:00 How she got onto the speaking stage49:40 Tapping into her intuition55:00 Sometime the vitamin pills are not natural How to Contact www.genuinelymaria.comhttps://www.linkedin.com/in/maria-garcia-7273a8230/https://www.facebook.com/profile.php?id=61565412543083 https://www.instagram.com/genuinelymaria.wf/ ------------------All about Roy / Brain Gym & Virtual Assistants at ⁠https://roycoughlan.com/⁠ 

Welcome to the Speaking Podcast. Guest Maria Garcia shares her powerful story of resilience after a massive stroke at 25 and the long recovery that followed. Maria discusses relearning basic functions, writing her memoir Breaking Into Delight, and discovering a transformative nutritional approach years later that significantly improved her recovery. She now coaches others to reset their relationship with food and reclaim their health and purpose.   --- All Episodes can be found at ⁠⁠https://www.podpage.com/speaking-podcast/⁠   All about Roy / Brain Gym & Virtual Assistants at ⁠⁠https://roycoughlan.com/⁠⁠   #mariagarcia #speaker #wildfit    Bio of Maria Garcia Maria Garcia is a powerful example of resilience and self-discovery. After earning double majors in Finance and International Business, she initially made her mark in the corporate world. But her path took an unexpected turn when a massive stroke altered her life forever. Through sheer determination and a long, challenging recovery, Maria emerged stronger, with a deeper sense of purpose.Maria channeled her transformative journey into her memoir, Breaking Into the Light: A Journey of Self-Discovery and Transformation, sharing her journey and the lessons learned along the way. Almost a decade after the book's release, she discovered a groundbreaking nutritional methodology, which played a pivotal role in her continued recovery and personal transformation.Today, Maria is a passionate coach, committed to helping others navigate their own journeys of recovery and transformation. She specializes in guiding individuals to reset their relationship with food, unlocking profound shifts in their overall life experience. What we Discussed:   00:00 Intro   00:20 Who is Maria garcia   02:10 How she got ill   03:30 Organ donation company speaking to her family   04:40 What was going on in her head when she could not move for 2 weeks   05:30 Her 1st movement in her body   07:00 Getting scared when sh saw the Nurse walk in   07:50 Dr's do not always get it right   09:25 The Next stage after the hospital   10:30 Birth Control pills can be dangerous   12:30 When she went home in a wheelchair and diapers   14:15 What was going on in her head at this stage   15:20 How she got out of the wheel chair   16:10 How Yoga helped a lot   17:30 Investigating different ways to heal   18:53 How her family kept Hope Alive   20:05 Getting into Personal Development   23:52 The importance of rereading a good book   26:00 When she found an ad about Nutrition   28:25 Developing a career on Nutrition   30:13 How the Food has been made toxic   30:30 The Wheel of Health   32:30 People lost touch with Nature   33:23 How to find healthy food   35:00 The Food Pyramid was inverted   35:40 Listen to your body   36:50 Pringles are not healthy or safe   38:30 Pork and Chicken are not the best meat to eat   39:45 What has she seen of illnesses being cured   41:30 How I cured my back pain   43:30 How they create confusion with food   46:10 Her Book on the journey   48:00 How she got onto the speaking stage   49:40 Tapping into her intuition   55:00 Sometime the vitamin pills are not natural   How to Contact ⁠www.genuinelymaria.com⁠ ⁠https://www.linkedin.com/in/maria-garcia-7273a8230/⁠ ⁠https://www.facebook.com/profile.php?id=61565412543083 ⁠ ⁠https://www.instagram.com/genuinelymaria.wf/ ⁠ ------------------ All about Roy / Brain Gym & Virtual Assistants at ⁠⁠https://roycoughlan.com/⁠⁠  

Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition. 00:00 - Christmas magic ✨ 04:10 - Dr. Mike's distain for modern Batman 06:05 - Bodybuilders ≠ Hollywood 12:20 - Muscle loss isn't one-size-fits-all 24:30 - Does diet duration effect muscle loss? 28:30 - Do men lose more muscle when dieting? 34:40 - Are people losing excess muscle on Ozempic? 40:40 - Organ size shifts when gaining and losing fat 44:00 - Factors that make muscle loss worse in a deficit 50:15 - Setting realistic body fat targets 1:00:00 - Best rate of loss / Protein intake / Cardio for muscle retention 1:06:00 - Objections to modern weight loss drugs 1:12:45 - Carb/macro intake for muscle retention  

View This Week's Show NotesStart Your 7-Day Trial to Mobility CoachJoin Our Free Weekly Newsletter: The AmbushWhat if the key to longevity isn't found in your heart, your brain, or your hormones — but in your muscle?In this episode of The Ready State Podcast, Dr. Gabrielle Lyon explains why skeletal muscle is the most overlooked organ in modern medicine and how its decline quietly drives aging, disease, and loss of independence. Drawing from her work in nutrition, geriatrics, and muscle-centric medicine, Lyon breaks down how strength training, protein intake, and daily movement protect metabolic health, resilience, and mental clarity as we age. From preventing sarcopenia to rethinking weight loss, GLP-1 drugs, and what it really means to age well, this conversation offers practical insights for anyone who wants to stay strong, capable, and useful for life. If you care about longevity, this episode reframes the conversation — starting with muscle!WHAT YOU'LL LEARN IN THIS EPISODE● Why cardiovascular disease, diabetes, obesity, and dementia often begin in skeletal muscle● What “muscle-centric medicine” means — and why it challenges modern healthcare● Why building muscle for longevity is the important thing you can do● How GLP-1 drugs could unintentionally accelerate muscle loss and sabotage longevity● Why body fat percentage misses the real metabolic problem● How resistance training protects the brain, joints, and metabolism● The protein framework Lyon uses in clinical practice● Why movement is the fastest path to physical and mental freedomTIMESTAMPS(00:00) - Dr. Gabrielle Lyon(01:20) - What Kind of Doctor Are You(06:45) - Muscle-Centric Medicine Explained(14:18) - Vitality Blueprint: $50 Off Plans(16:45) - Role of a Muscle-Centric Physician(19:15) - Muscle: The Organ of Longevity(24:04) - Muscle Mass and Dementia Prevention(27:10) - Fear of Resistance Training(29:55) - Concerns About Being Too Bulky(33:20) - LMNT(35:00) - Subscribe to the Podcast(32:50) - Importance of Healthy Muscle Mass(40:00) - Best Ways to Measure Health Aging(44:27) - Nutrition Insights(50:07) - Staying Forever Young(51:23) - Start Your Momentous Journey(53:20) - The Forever Strong Playbook Overview(54:15) - Understanding GLP-1s(57:47) - Muscle-Centric Strength Program Overview(59:35) - Expectations from The Forever Strong Playbook(1:00:25) - Dr. Lyon's addition to the Infinite Shelf(1:01:11) - Finding Dr. Gabrielle LyonHuge thanks to our sponsors, Vitality, Momentous, and LMNT.Connect with Dr. LyonWebsite | Instagram | YouTubePre-Order The Forever Strong PLAYBOOKOrder Forever Strong