Podcasts about Aging brain

View This Week's Show NotesStart Your 7-Day Trial to Mobility CoachJoin Our Free Weekly Newsletter: The AmbushWhat if the biggest predictor of dementia isn't your genes — but your metabolic health?In this episode, neuroscientist and performance coach Dr. Tommy Wood reveals why blood sugar regulation and blood pressure are more powerful predictors of Alzheimer's disease and cognitive decline than amyloid plaques or even genetics like ApoE4.For decades, Alzheimer's has been framed as either a genetic lottery or the inevitable buildup of amyloid in the brain. But emerging research shows that metabolic dysfunction, insulin resistance, and vascular health may play a far greater role in determining long-term brain outcomes.Instead of focusing on fear, this conversation delivers a practical blueprint for building cognitive reserve and “cognitive headroom” — the brain's ability to stay resilient, adaptable, and high-performing as you age.You'll learn why crossword puzzles aren't enough, how high-intensity exercise and resistance training stimulate brain-derived neurotrophic factors (BDNF), why lactate may act like “Miracle-Gro” for your neurons, and how to interpret early warning signs like subjective brain fog.What You'll Learn in This EpisodeWhy Alzheimer's isn't just about amyloid plaquesThe powerful link between blood sugar and cognitive declineHow genetics (like ApoE4) increase risk — but don't seal your fateWhat “cognitive headroom” means and how to build itWhy high-intensity exercise may act as Miracle-Gro for the brainThe surprising role of resistance training in brain healthWhat subjective brain fog might be telling youHow menopause affects cognition — and what's reversibleWhy boredom and focus matter more than we thinkThe kinds of skills you should keep practicing as you ageFor women navigating perimenopause and menopause, Dr. Wood explains what cognitive changes are hormonally driven, what's reversible, and how to protect long-term brain health.Whether your goal is preventing Alzheimer's disease, improving focus and processing speed, or becoming a cognitive “superager,” this episode provides evidence-based strategies to help you build a brain that is robust, metabolically healthy, and built to last.Key Highlights: (00:00) – Brain Health & Cognitive Longevity Intro(00:35) – Brain Evolution & Survival Mechanisms(02:53) – Diabetes & Alzheimer's Disease Link(07:31) – Genetic Risk & Dementia Family History(11:32) – Expanding Brain Capacity & Headroom(15:08) – Cognitive Reserve & Brain Resilience(19:55) – Preventing Age-Related Cognitive Decline(23:00) – Exercise Data for Brain Health(26:16) – Best Exercises for Cognitive Function(35:11) – Amyloid Plaques & Alzheimer's Pathology(38:00) – Amyloid-Targeting Drugs & Treatments(40:31) – Subjective Cognitive Decline Measures(45:04) – Testing & Measuring Brain Performance(49:58) – Menopause & Female Brain Health(56:10) – Aging Brain, Wisdom & Intelligence(1:05:00) – Cognitive Processing Speed & Aging(1:07:07) – Benefits of Boredom for the Brain(1:12:17) – Book Recommendations for Mental GrowthConnect with Dr. Tommy WoodWebsite | Substack | InstagramPre-Order The Stimulated Mind for tons of extra perks!Huge thanks to our sponsors, Momentous, Vitality, and LMNT.

Can the aging brain still make new neurons?   A landmark 2026 Nature study analyzed 355,997 human hippocampal nuclei using single-nucleus RNA sequencing and ATAC sequencing. Neurogenesis persists into adulthood—but chromatin accessibility collapses early in Alzheimer's disease.   SuperAgers showed a 2.5-fold increase in immature neurons and a preserved resilience signature.   Epigenetics may be the earliest battlefield in cognitive decline.

Send a textDonna Letier is the Co-Founder and CEO of Gardenuity ( https://gardenuity.com/ ), a gardening and well-being company dedicated to helping people grow healthier lifestyles through accessible, personalized gardening experiences.An entrepreneur with a background spanning consumer brands, hospitality, and lifestyle innovation, Donna launched Gardenuity to bridge the gap between everyday wellness and nature — making gardening approachable even for people without outdoor space, time, or prior experience.Under her leadership, Gardenuity has pioneered customized container and desktop gardening systems designed to support mental health, stress reduction, nutrition, and meaningful daily rituals. Her work sits at the intersection of preventive health, behavioral wellness, and environmental connection, with growing recognition of gardening's role in cognitive health, emotional regulation, and caregiver resilience.Donna is also an advocate for using gardening as a tool for intergenerational connection and memory engagement, exploring how sensory interaction with plants — from scent and touch to nurturing routines — can support individuals living with memory loss while providing caregivers with moments of restoration and purpose.#Alzheimers #BrainHealth #CognitiveHealth #DementiaCare #CaregiverSupport #HealthyAging #Longevity #Neuroplasticity #MentalWellness #PreventiveHealth #Gardening #HorticulturalTherapy #MemoryCare #AgingWell #LifestyleMedicine #Wellness #BrainLongevity #Caregiving #NatureHeals #ProgressPotentialPossibilitiesSupport the show

Dr. Tony Wyss-Coray, PhD, is a professor of neurology at Stanford School of Medicine who is discovering factors present in young blood and in exercised blood that can improve brain, heart and other organ health. We discuss how different organs age at different rates and how to accurately measure biological aging. We also discuss the specific proteins found in blood when we are young and that are increased by things such as exercise, sunlight exposure, short-term fasting, specific foods and social connection that can significantly increase vitality, restore youthful functioning of the brain and body and potentially increase lifespan. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman LMNT: https://drinklmnt.com/huberman ROKA: https://roka.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00:00) Tony Wyss-Coray (00:03:00) Young vs Old Animals, Age-Related Disease (00:06:35) Blood Biomarkers, Young vs Old Humans, Alzheimer's Disease (00:12:50) Sponsors: David & LMNT (00:15:28) 'Young Blood' Factors, Rejuvenation, Stem Cells (00:20:15) Blood Banking; Dracula (00:23:10) Rates of Aging in Organs, Age Gap & Disease Risk; Risk Profiles & Therapies (00:33:02) NAD Levels & Aging, NMN Supplements (00:36:44) Vitality vs Longevity; Periods of Accelerated Aging (00:43:17) Sponsors: AG1 & Roka (00:45:22) Sunlight; Youthful Blood Factors, Exercise & Brain Function, Fasting (00:51:25) Exercise, Injury & Inflammation (00:56:18) Pro-health Factors, Klotho, GDF11, Stem Cell Injection Risk (01:02:35) Platelet-Rich Plasma (PRP); Exosomes (01:05:43) Smoking, EMFs, Plastics, Long-Term Accumulation, Fresh Foods, Organic Food (01:11:28) Sponsor: Function (01:13:16) Intermittent Fasting, Long-Term Fasting, Snacking (01:19:07) Sleep; Cerebrospinal Fluid (CSF) Factors & Cognitive Function (01:24:44) Exercise Type & Longevity; Exercise Enjoyment (01:32:02) Lifestyle Factors & Alzheimer's Risk; Cognitive Exercise; Chocolate (01:37:05) Alcohol & Social Connection; US vs European Food Culture (01:40:50) Deliberate Deep Breathing; Wearables, Sunlight & Artificial Light (01:49:13) Future Projects (01:56:40) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Patty and Brian talk about the aging brain and the different stages and categories of intelligence. They opine with researchers in this area about what this could mean for our thinking.

Chronic stress and anxiety are not just emotional experiences; they can quietly accelerate biological aging and undermine brain health. In this episode of Growing Older Living Younger, Dr. Gillian Lockitch speaks with integrative mental health expert Dr. Nicole Cain about how anxiety, panic, trauma, and unresolved stress shape the nervous system across the lifespan. Dr. Cain explains the critical differences between fear, anxiety, and panic, and how symptoms often serve as meaningful signals rather than disorders to suppress. This rich conversation offers science-backed, compassionate strategies to restore calm, improve resilience, and support healthy aging from the inside out. Dr. Nicole Cain is a licensed naturopathic physician based in Arizona with a master's degree in clinical psychology. She is a pioneer in trauma-informed, integrative mental health care, blending medical science, psychotherapy, EMDR, nutrition, and nervous system regulation to address anxiety and mood disorders at their roots. Dr. Cain is the author of Panic Proof: How to Rewire Your Brain for Calm in a Chaotic World and host of the Holistic Inner Balance podcast.  Episode Timeline  00:00 – Welcome and episode framing -Dr. Gillian Lockitch introduces the theme of retraining the brain for calm, focus, and joy as we age.  03:33 – Dr. Cain's personal journey into anxiety healing -A childhood shaped by hyper-attunement, family stress, and early medicalization of anxiety.  05:14 – Medication, burnout, and the limits of symptom suppression =How conventional approaches failed to resolve root causes and led to a pivotal turning point.  07:29 – Seasonal illness, stress, and nervous system patterns -Exploring how environment, family dynamics, and stress imprint the immune system.  08:27 – Anxiety versus panic - Clarifying distinctions between fear, anxiety, and panic through lived experience and physiology.  11:19 – Fear of change and uncertainty - How major life transitions can activate panic responses even in resilient individuals.  16:39 – Agency as the antidote to anxiety - Why reclaiming personal authority calms the nervous system more than explanations alone.  19:57 – Stress, inflammation, and accelerated aging - How chronic cortisol exposure affects the gut, brain, and immune system over time.  20:27 – The gut-brain axis and anxiety - A clinical example showing how gut inflammation drives cognitive and emotional decline.  24:53 – Trauma-informed care and adaptive events - Reframing trauma as adaptation and understanding when survival strategies become maladaptive.  28:52 – Personalized nutrition and body awareness - Why no single diet fits everyone and how curiosity leads to sustainable healing.  33:36 – Interoception and mindful self-observation - Learning to listen to the body without panic, avoidance, or over-fixing.  37:09 – Mindset, neuroplasticity, and imagination - How intention and mental rehearsal reshape brain wiring and biological outcomes.  40:43 – A simple breath practice for immediate calm - Using breath and vagal tone to restore balance and resilience.   Resources & Links Mentioned  Dr. Nicole Cain Panic Proof: How to Rewire Your Brain for Calm in a Chaotic World by Dr. Nicole Cain  The Holistic Inner Balance Podcast  https://www.DrNicoleCain.com/  https://www.PanicProof.com/  https://www.instagram.com/drnicolecain/  https://www.facebook/drnicolecain/   https://www.penguinrandomhouse.com/books/737883/panic-proof-by-dr-nicole-cain/  https://campsite.bio/drnicolecain   Call to Action  Join the Growing OlderLiving Younger Community Invite Your Friends to Subscribe to Growing Older Living Younger on their favorite podcast platform. Leave a review to help others discover the Growing Older Living Younger show.  Explore your personal roadmap to longer healthspan and emotional resilience by connecting with Dr. Gillian Lockitch at askdrgill@gmail.com  

More than 500,000 Canadians live with dementia -- an overall term for a set of symptoms caused by disorders affecting the brain such as Alzheimer's disease. There is currently no cure or treatments that can reverse dementia however, through research, St. Joseph's Lawson scientists, led by Dr. Michael Borrie, Medical Director for St. Joseph's Aging Brain and Memory Clinic, a key member of the Canadian Consortium on Neurodegeneration and Aging (CCNA) and Program Director of the South Western Ontario Regional Geriatric Program, are completing clinical trials on medications and treatments that can slow and sometimes stop the progression of the disease.  On this episode of the DocTalks Podcast, Dr. Borrie joined host Mandi Fields to discuss the dementia research happening at Lawson Research Institute of St. Joseph's. You can listen to the previous episode with Dr. Borrie where he discusses what dementia is, here.  If you are interested in taking part in the studies Dr. Borrie mentions in this episode, please contact Julia Truemner, Research Coordinator, at memory@sjhc.london.on.ca or 519-64661000 Ex 46600. If you would like to help support Dr. Borrie's research, please visit the St. Joseph's Health Care Foundation's website and learn more about making a donation. 

Londinium 91 AD: The Aging Emperor's Urgency. Gaius and Germanicus discuss the physical and mental state of emperor Trump, noting his senior age and frantic, restless pace as potentially signs of an aging brain or alternatively adrenaline and confidence. Germanicus believes the emperor is acutely self-aware of his limited time, driven by tremendous brutal urgency to secure a lasting legacy including fiscal stability, border control, and eliminating principles like DEI. However, the stress of this frantic pace combined with age could cloud his judgment, making him more impulsive or desperate. The emperor's focus on revenge cycles, such as indicting former directors, is typical of historical emperors against their enemies. Germanicus worries this could lead to physical decline and reckless action. A critical marker of a republic's collapse into an emperor system is when the incoming president pursues and imprisons his predecessor, an easy push into civil war seen in places like Brazil. They conclude the transition is quietly happening, with the question of whether the U.S. will experience violence remaining unknown. 81 BCE SULLA Retry

Everything is connected. Like the connection between oral hygiene and brain health. In this episode of Defy Dementia™, we'll join Dr. James Noble, Professor of Neurology and author of Navigating Life with Dementia, as he discusses how poor oral health and inflammation could increase dementia risk, and just how important oral care is for brain health. We'll also follow 65-year-old Ben Schaub, a journalist specializing in science and technology – and a Defy Dementia producer – as he shares how he keeps his brain healthy by taking care of his oral health. Tune in at defydementia.org, or anywhere you get your podcasts. Key Messages: Gum infections are common, especially in older adults. Maintaining healthy teeth and gums benefits your overall health and may reduce your dementia risk. Key Actions: Brush and floss daily.If available, visit your dental professional for regular cleaning and check-ups or if you are experiencing issues with your teeth or gums. About our guests: Ben Schaub is an award-winning science journalist and Defy DementiaTM's writer and chase producer. Ben researched episodes of CBC's The Nature of Things and produced interviews and documentaries for Discovery Channel Canada's Daily Planet.  Dr. James Noble is a Professor of Neurology in the Taub Institute for Research on Alzheimer's Disease and the Aging Brain at Columbia University Irving Medical Center. He was the first to discover an association between the periodontal pathogen Porphyromonas gingivitis and impaired memory, and leads a project exploring the relationship of oral health conditions and cognitive trajectories. He is also the author of Navigating Life with Dementia.

Mental health and neuroscience experts discuss the aging brain.

In this episode, Rev. Oliver Helsabeck talks with Dr. Edward Shaw, a physician, mental health counselor, and dementia care specialist about the challenges of dementia, Alzheimer's disease, and caregiving that impact many families. Dr. Shaw founded the Memory Counseling Program that serves people impacted by dementia and Alzheimer's disease as part of the Sticht Center at Atrium Health Wake Forest Baptist in Winston-Salem. Dr. Shaw will present a program on dementia and the aging brain on Sunday, October 19 at 5:00 p.m. in Memorial Auditorium. The program, “Anchored in Love: Understanding the Aging Brain and Dementia; Supporting Parents, Family, and Loved Ones as Care Partners,” is open to the public and sponsored by Centenary's Stephen Ministry and Shining Light on Mental Health Ministry.

A recent study in the journal GeroScience investigated how age-related declines in cellular energy, specifically the molecule Guanosine triphosphate (GTP), affect waste clearance in brain cells. Using hippocampal neurons from an Alzheimer's disease (AD) mouse model, researchers found a significant, age-dependent reduction in free GTP levels, which was accelerated in the AD model neurons. This energy deficit was shown to impair critical cellular processes like endocytosis and autophagy, leading to the accumulation of toxic amyloid-beta (Aß) aggregates and increased protein oxidation. Remarkably, the researchers then treated aged neurons for 24 hours with a combination of nicotinamide (a precursor to the energy-related molecule NAD+) and EGCG (a redox modulator found in green tea). This treatment was highly effective, restoring the depleted GTP levels in aged neurons all the way back to the normal, youthful levels seen in healthy, young neurons. This restoration of cellular energy enhanced the clearance of Aß aggregates and improved the viability of aged AD model neurons by 22%.Disclaimers• "This information is for educational purposes only and should not be interpreted as medical advice."• "The study discussed was conducted in vitro on neurons isolated from mice. Further research is needed to confirm these findings in humans."• "Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications."• "This channel is not monetized and does not provide medical advice."#GTP #Autophagy #AlzheimersResearch #Nicotinamide #EGCGSource: Santana, R. A., McWhirt, J. M., & Brewer, G. J. (2025). Treatment of age-related decreases in GTP levels restores endocytosis and autophagy. GeroScience. https://doi.org/10.1007/s11357-025-01786-4Guanosine triphosphate, GTP, Alzheimer's disease, neuronal aging, autophagy, endocytosis, bioenergetics, nicotinamide, EGCG, NAD+, Nrf2, 3xTg-AD mouse model, proteostasis, amyloid-beta clearance, Aß aggregates, mitochondrial dysfunction, cellular energy, redox state, Rab7, Arl8b, neuronal viability, protein oxidation, neurodegeneration, in vitro study, hippocampal neurons

Nutritionist Leyla Muedin discusses recent advancements in the detection and prevention of Alzheimer's disease. Topics include the new FDA-approved Lumipulse blood test, the role of a ketogenic diet in improving mitochondrial health, and the significance of lifestyle changes such as social and cognitive activities. The episode also highlights promising research from the University of California Irvine on using natural compounds like nicotinamide and EGCG to rejuvenate aging brain cells and address the buildup of Alzheimer's-associated proteins. Leyla also provides insights into the difference between Alzheimer's and general dementia and emphasizes the importance of accurate diagnosis and appropriate treatments.

Growing evidence shows that Alzheimer's risk is shaped not only by genetics but also by culture, environment, and lifestyle — and researchers say these differences may hold the key to better prevention and treatment.Dr. Sid O'Bryant, professor of pharmacology and neuroscience at the University of North Texas, is the principal investigator of the Health & Aging Brain Study – Health Disparities (HABS-HD), the most comprehensive Alzheimer's study ever conducted across African American, Hispanic, and non-Hispanic white communities. His approach brings research into diverse communities often left out of large-scale studies, ensuring that findings reflect the populations most at risk.In this conversation with Being Patient's Mark Niu, O'Bryant explained how factors like diabetes, hypertension, environment, and even social support networks shape brain health. He explained that these findings show why Alzheimer's cannot be treated with a “one size fits all” model. Instead, precision medicine — tailoring prevention and treatment strategies to an individual's genetic, cultural, and lifestyle background — could transform how we approach brain health and Alzheimer's treatments.

As the autistic brain ages, is it more vulnerable to other brain disorders? Recent scientific discoveries in Parkinson's Disease and Alzheimer's Disease show that there may be an underlying mechanism between these diseases and autism. However diagnosing someone with autism with an additional brain disorder, especially dementia, can be difficult. This week's podcast covers the … Continue reading "Autism and diseases of the aging brain"

Timothy Jennings - The Aging Brain by Bill and Sandi Griffin

In this episode we slow-walk a brand-new Psych/Soc passage—“Aging Brain” showing you, sentence-by-sentence, how top scorers:- Decode unfamiliar social-science jargon without getting stuck- Spot author attitude and trap wording that hide inside “friendly” topics- Build quick mental maps that link each paragraph back to the central thesis- Translate real-world quotes (yes, even a Henry Ford cameo) into testable MCAT questions- Turn every practice passage into timed, active-reading reps you can repeat on exam day

Send us a textWhat if the key to a healthier, sharper brain wasn't a pill or a special diet—but simply getting up and moving your body every day? In this episode of the Strong By Design podcast, Coach Chris Wilson sits down with Dr. Charles Hillman, a world-renowned expert in cognitive neuroscience, exercise science, and neurocognitive kinesiology. Dr. Hillman has dedicated his career to understanding how physical activity affects brain function and cognitive performance, especially in children and older adults.Their conversation explores how movement shapes the brain across the lifespan, from childhood to old age. Dr. Hillman shares groundbreaking research—like how fit kids have larger hippocampal volumes and stronger memory skills, and how lifelong activity can help protect against age-related cognitive decline. He also discusses how a sedentary lifestyle can harm both physical and cognitive health, why schools need to prioritize physical education, and how parents can create movement-rich environments at home to support their kids' brain development. Dr. Hillman's work has even influenced U.S. public health policy through the 2018 Physical Activity Guidelines, showing that staying active isn't just good for the body—it's essential for brain health and lifelong learning.This is a powerful conversation for anyone who wants to stay sharp, feel energized, and keep their brain and body healthy for years to come.Time Stamps00:39 – Welcome to the Strong By Design podcast!01:24 – Join Coach Chris Wilson with special guest, Dr Charles Hillman04:34 – How Dr. Charles (Chuck) developed his fascination with the brain 12:30 – Coach Chris shares his passion for fitness and health14:25 – How early-life activities influence the way we age18:49 – What is the main reason many people don't exercise?22:08 – Learn about the health risks of being out of shape26:51 – Our lack of emphasis on physical activity and physical education31:26 – How other countries prioritize physical activity and health36:04 – How physical movement influences key areas of brain function40:45 – Chuck talks about sports and the study of movement49:14 – Can your body easily bounce back after years without exercise?54:50 – Benefits of being physically active as a family59:33 – Please share and leave ratings and reviews for the SBD podcast!We would be honored if you would leave a Rating or Review for the Strong By Design Podcast.Leave a Rating or Review on iTunes Resources:TEDx Talk - How lifelong movement supports your brain - Christopher Wilson Connect with Chuck:Northeastern University College of Science Connect with Chris:InstagramLow Testosterone? Buy 1 Get 2 Free Critical T Supplement: www.criticalnutritionlabs.com Low Testosterone? Buy 1 Get 2 Free Critical T Supplement: www.criticalnutritionlabs.comSupport the showConnect w/ CriticalBench: Youtube Facebook Instagram CriticalBench.com StrongByDesignPodcast.com

Eric Collett is the man who's rewriting the script on brain health and challenging everything we thought we knew about aging. Imagine a world where Alzheimer's isn't an inevitable decline, but a preventable condition. That's not science fiction - that's Eric's mission. A former memory care executive turned brain health revolutionary, Eric went from running a struggling care facility to developing a groundbreaking protocol that's helping people reverse cognitive decline - we're talking about Parkinson's patients doing jumping jacks after being wheelchair-bound, and dementia patients dramatically improving their cognitive scores.   With a childhood dream of building flying machines and a professional journey that's taken him from caring for seniors to consulting with NFL athletes, Eric isn't just another health expert - he's a visionary who believes your brain's potential is limited only by your willingness to understand and nurture it. His company, A Mind for All Seasons, isn't just treating symptoms - they're uncovering the root causes of neurological challenges, from dental health to environmental toxins.   If you've ever wondered whether cognitive decline is truly inevitable, or if you're ready to take control of your brain's future, this conversation will change everything you think you know about health, aging, and human potential.   Connect with Eric Collett on his website: https://amindforallseasons.com/  On LinkedIn: https://www.linkedin.com/company/a-mind-for-all-seasons/    = = = = = I write for people who want more signal, less noise. If that's you, come find me here: gobeyondthescroll.com Join the AI Conversation You've Been Waiting to Have without the Hype or Chaos.  Get my books here:   The River Only Runs One Way  The Far Unlit Unknown = = = = = Thank you for supporting the show! Your 5-star rating and review makes a difference -- it's easy to leave one and it helps spread the word about the podcast! Best social places to connect with me:  @maryloukayser (Instagram) https://www.linkedin.com/in/mlkayser/ (LinkedIn)

As we age, our brains become more sensitive to stress and disease. A recent study sheds light on a lesser-known risk: reduced oxygen levels. The study, titled “Defining the hypoxic thresholds that trigger blood-brain barrier disruption: the effect of age” and recently published as the cover for Volume 17, Issue 5 of Aging (Aging-US), found that low oxygen—also called hypoxia—can harm the aging brain by disrupting the blood-brain barrier (BBB). This damage may contribute to cognitive decline, memory problems, and an increased risk of dementia. Understanding Hypoxia in the Brain The brain relies on a steady supply of oxygen to stay healthy. When oxygen levels fall—a condition known as hypoxia—the brain undergoes changes to adapt. These changes include the remodeling of blood vessels and, importantly, a weakening of the blood-brain barrier. The BBB acts as a filter, protecting brain tissue from harmful substances. When it breaks down, it can lead to inflammation, brain cell damage, and cognitive issues. Hypoxia is common in older adults, especially those with conditions like sleep apnea, chronic obstructive pulmonary disease (COPD), heart failure, and asthma. That is why understanding the connection between low oxygen and the aging brain is crucial for preventing long-term neurological damage. Full blog - https://aging-us.org/2025/06/oxygen-deprivation-and-the-aging-brain-a-hidden-trigger-for-cognitive-decline/ Paper DOI - https://doi.org/10.18632/aging.206241 Corresponding author - Richard Milner - rmilner@sdbri.org Video short - https://www.youtube.com/watch?v=Nr6rTm7aJRo Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206241 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, blood-brain barrier integrity, endothelial, proliferation, microglia, chronic mild hypoxia, hypoxic threshold To learn more about the journal, please visit our website at https://www.Aging-US.com​​ and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Bluesky - https://bsky.app/profile/aging-us.bsky.social Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

In this conversation, Dr. Tara Walker discusses the fascinating topic of adult neurogenesis, the brain's ability to produce new neurons throughout life. She explains how this process is crucial for cognitive function and how it declines with age. The discussion highlights the significant role of exercise in boosting neurogenesis and introduces selenium as a key factor in this process. Dr. Walker also explores the implications of her research for cognitive health, particularly in the context of neurodegenerative diseases, and the potential therapeutic strategies that could arise from understanding neurogenesis better.

In this episode of ‘The Aging Well Podcast', Dr. Dr. Armstrong's guest is Dr. Pria Anand, author of ‘The Mind Electric.' They discuss the intricate relationship between storytelling, aging, and the brain. Dr. Anand emphasizes that aging is not merely a decline but a complex transformation that involves both challenges and improvements in cognitive functions. The discussion explores neurodegenerative diseases, the impact of infections and autoimmune disorders on brain health, and the critical role of patient narratives in diagnosis and treatment. Dr. Anand advocates for better communication in healthcare and highlights the importance of patient advocacy in navigating the medical system and the challenges faced by women and underrepresented genders in navigating the healthcare system, emphasizing the importance of self-advocacy. She shares her journey of balancing a medical career with creative writing, highlighting how motherhood has shaped her priorities. The discussion considers the lessons learned from neurology that can be applied to everyday life, particularly the significance of storytelling in understanding our experiences and its impact on aging. The conversation concludes with a look at the future of neurology and the importance of continued research in sleep science for… aging well.Learn more about Dr. Anand and the book at:https://www.priaanand.com/https://www.simonandschuster.com/books/The-Mind-Electric/Pria-Anand/9781668064016Please, support The Aging Well Podcast by hitting the ‘like' button, subscribing/following the podcast, sharing with a friend, and….BUY ‘The Mind Electric' on Amazon and support ‘The Aging Well Podcast': https://amzn.to/4m8tUAnBUY the products you need to… age well from our trusted affiliates and support the mission of ‘The Aging Well Podcast'*.Thrive25—Your personal longevity advisor | https://www.thrive25.com/early-access?via=william-jeffreyMemory Lane TV | the first therapeutic streaming platform for people living with dementia — designed to replace overstimulating television with multisensory, evidence-based media that soothes, orients, and restores | for 30% off the annual subscription visit https://www.memory-lane.tv/?rfsn=8714090.a500b0Fusionary Formulas | Combining Ayurvedic wisdom with Western science for optimal health support. | 15% off Code: AGINGWELL | https://fusionaryformulas.com/Jigsaw Health | Trusted supplements. “It's fun to feel good.” | Click the following link for 10% off: https://www.jigsawhealth.com/?rfsn=8710089.1dddcf3&utm_source=refersion&utm_medium=affiliate&utm_campaign=8710089.1dddcf3Auro Wellness | Glutaryl—Antioxidant spray that delivers high doses of glutathione (“Master Antioxidant”) | 10% off Code: AGINGWELL at https://aurowellness.com/?ref=1957Dr Lewis Nutrition | Fight neurodegeneration and cognitive decline with Daily Brain Care by Dr Lewis Nutrition—a proven daily formula designed to protect and restore brain function. | 10% off code: AGINGWELL or use the link: https://drlewisnutrition.com/AGING WELLTruDiagnostic—Your source for epigenetic testing | 12% off Code: AGEWELL or use the link: https://shop.trudiagnostic.com/discount/AGEWELL*We receive commission on these purchases. Thank you.

In this episode of the Gladden Longevity Podcast, Dr. Jeffrey Gladden and co-host Autumn Calabrese delve into various listener questions surrounding longevity, mental health, stress management, blood pressure, hormonal health, and the potential of new medications in promoting a longer, healthier life. They explore the interconnectedness of mental well-being and longevity, the importance of managing stress, and the role of hormones in maintaining health as we age. The conversation also highlights practical lifestyle changes and emerging scientific insights that can help individuals optimize their health and longevity.   For Audience        Use code 'Podcast10' to get 10% OFF on any of our supplements at https://gladdenlongevityshop.com/ !    Takeaways ·       Mental health and stress significantly affect longevity. ·       Healing trauma and feeling safe are crucial for stress management. ·       Forgiveness can reduce stress and inflammation. ·       Blood pressure should be optimized for long-term health. ·       Hormonal balance is essential for vitality and longevity. ·       Curiosity and continuous learning keep the brain young. ·       Meditation and relaxation techniques improve cognitive function. ·       Diet plays a critical role in mental health and stress levels. ·       New medications may offer longevity benefits beyond traditional uses. ·       Research and understanding of hormone therapy are vital for health.   Chapters 00:00 Mental Health and Longevity 09:16 Blood Pressure and Cardiovascular Health 15:04 Hormones and Women's Health 20:03 Brain Flexibility and Aging 25:53 Emerging Longevity Medications   Reach out to us at:    Website: https://gladdenlongevity.com/     Facebook: https://www.facebook.com/Gladdenlongevity/    Instagram: https://www.instagram.com/gladdenlongevity/?hl=en     LinkedIn: https://www.linkedin.com/company/gladdenlongevity    YouTube: https://www.youtube.com/channel/UC5_q8nexY4K5ilgFnKm7naw  

Is your memory decline normal—or something more? Clinical neuropsychologist Dr. Mitchell Clionsky breaks down what healthy aging looks like from a cognitive perspective and where concern might be warranted. He introduces the Memory Orientation Screening Test (MOST)—a powerful yet quick tool to assess cognitive health—and shares insights from decades of evaluating memory, dementia, brain injuries, and CTE. From preventive strategies that could reduce dementia risk by nearly 50%, to how technology is transforming neuropsychology, this conversation is a must-watch for anyone invested in long-term brain health. Learn more about Dr. Mitchell Clionsky: https://www.linkedin.com/in/mitchell-clionsky-4b8b275b/ - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/

Send us a textIn this episode of Causes or Cures, Dr. Eeks chats with Dr. Amir Baniassadi about how indoor temperature affects the aging brain.Dr. Baniassadi shares what we know so far about the relationship between temperature and cognitive function, and explores the theories behind how temperature might influence cognition as we age. He discusses the findings of his recent study on temperature and cognition, including what surprised his team most. He also touches on an earlier study he conducted on temperature and sleep, and offers practical tips for optimizing your home environment. Is there a “sweet spot” for room temperature that supports both clear thinking and better sleep?Dr. Baniassadi is an instructor of medicine at Harvard Medical School and a scientist at the Marcus Institute for Aging Research. His work focuses on the aging brain and how environmental factors affect health and well-being in older adults. He holds a PhD in Civil, Environmental, and Sustainable Engineering from Arizona State University and an undergraduate degree in Mechanical Engineering from the University of Tehran. He also completed postdoctoral training in Translational Research in Older Adults, as well as a fellowship at the Harvard Graduate School of Design.Learn more about his work here. You can contact Dr. Eeks at bloomingwellness.com.Follow Eeks on Instagram here.Or Facebook here.Or X.On Youtube.Or TikTok.SUBSCRIBE to her monthly newsletter here.Support the show

While growing older is inevitable, many of the troubles we associate with aging – including dementia, disability, and an increased dependence on others – are not. The choices we make now can help us to maintain our vitality, a sharp mind, and our independence as we age. Dr.Timothy Jennings will guide us as we learn how to maintain brain and body health throughout our lives. He will provide solid, up-to-date scientific research that not only prevents progression toward dementia, but will also reduce disability and depression and keep people living independently longer than those who do not practice these methods.Become a Parshall Partner: http://moodyradio.org/donateto/inthemarket/partnersSee omnystudio.com/listener for privacy information.

Can an aging senior with memory issues navigate the digital world?  I offer a solution.  A new client had an affair with a married man. Now her religious parents are furious, her lover is over the top mad she let her parents find out, his wife hates my client and has sunk into depression and this client wants to know what to do. My path forward is an outside the box approach that just might thread the needle. Have you ever seen a sentence with three cliches? In episode 127 I infuriated some political conservatives and country music fans and to make up for that unintended slight I wrote and recorded a song to show I do love country music and use it to sincerely apologize to them. My new song is called "We Thank God For Being an American" and I am very proud of it. In fact, I think I may have a hit on my hands. Please take a listen and let me know what you think. Subscribe and THRIVE!!!!

Your brain health is super important during menopause, so how can we sustain it? In this episode, Adele discusses the aging brain and how to keep it healthy for longer, learning how menopause impacts your cognitive health. A link to Adele's checklist: https://adelejohnstoncoaching.com/checklist-optin Download Adele's Journey Journal here : https://adelejohnstoncoaching.com/my-journey-journal/ Enquire about 121 coaching here : https://docs.google.com/forms/d/e/1FAIpQLSfw6vrmKPE7A1eYDKQJiR9No7ZDdpfq-grBdKYjZSR-vl0Qag/viewform For extra support: Support@adelejohnstoncoaching.com ____________ From your host : Adele Johnston I'm Adele Johnston, a certified nutritionist and positive psychology coach, passionate about helping women improve their menopause health and reclaim who you are without menopause taking over. This is a time in your life where you get to feel vibrant, sexy and reclaim you again! I'm proud to work with women like you and have created a very successful proven Reclaiming You 3 STEP PROCESS to help you take back control of your body during your menopause. For more details : https://adelejohnstoncoaching.com/ To get Adele's FREE 3-step Menopause Weight Loss Guide: https://adelejohnstoncoaching.com/menopause-weight-loss-guide/

In this episode of the Unreasonable Health Podcast, Cade Archibald kicks off The Ageless Brain five-part series, diving into the science of neuroinflammation, cognitive decline, and brain regeneration.He explores the role of peptides like Semax and Selank in reducing inflammation and enhancing neuroplasticity, alongside nootropics and lifestyle interventions that support brain health. Cade also introduces the NeuroCatch test, a cutting-edge tool for assessing cognitive function, and challenges listeners to engage in activities that boost neuroplasticity. Tune in to discover how to optimize your brain for longevity and peak performance!To optimize your brain, check us out! https://acueastwest.com/

Do psychiatric medications alter brain energy and metabolic health?Dr. Stephen Cunnane, a professor and researcher at the University of Sherbrooke, has been at the forefront of studying glucose and ketone metabolism in the aging brain, pioneering advanced imaging techniques to measure how the brain utilizes these critical energy sources with neurodegenerative conditions like Alzheimer's and Parkinson's.While glucose PET imaging has long been used to study brain energy metabolism, Dr. Cunnane's team was the first to develop ketone PET imaging, allowing researchers to look at the relationship between glucose and ketone metabolism in the brain and understand how ketones support brain function when it struggles to use glucose for energy.Now, Dr. Cunnane has turned his attention to metabolic psychiatry and is working on a new study looking at brain energy metabolism in individuals experiencing first-episode psychosis. This study will allow researchers insights into the metabolic state of the brain at the onset of major mental illness and how psychiatric medications influence brain energy use.In this episode, you will learn:How the brain uses fuel as we age – Why glucose metabolism declines over time and how ketones may compensate in aging and neurodegenerative conditions.The first ketone PET imaging studies – How Dr. Cunnane's team developed a method to directly measure ketone uptake in the brain and compare it to glucose metabolismPsychosis and brain energy metabolism – Examining glucose and ketone utilization in first-episode psychosis before and after antipsychotic treatment.Carbohydrate reduction in older adults – Findings from a study showing how moderate carb restriction improved metabolic and mental health in retirement home residents independent of weight loss.Parkinson's disease and ketones – Investigating how exercise, exogenous ketones, and carbohydrate restriction may enhance brain energy supply and improve symptoms.Dr. Cunnane has been a pioneer in the field of ketogenic therapy and brain energy. In addition to all the incredible work he is doing in the aging brain, we are excited to see his new research focusing on such critical components of metabolic psychiatry.Expert Featured:Dr. Stephen Cunnanehttps://recherche-cerveau-sherbrooke.ca/en/laboratory-team/Studies MentionedA reduced carbohydrate diet improves glycemic regulation in hyperglycemic older people in a retirement home: the SAGE studyhttps://doi.org/10.1139/apnm-2024-0277Resources MentionedBrain Research Team Websitehttps://recherche-cerveau-sherbrooke.ca/en/Revolutionizing Assisted Living: Hal Cranmer's Ketogenic & Carnivore Approach to Senior Wellnesshttps://youtu.be/s86CFw0qhVc?feature=sharedFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources athttps://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

In this episode of HYDRATE, Tracy breaks down the real science of hydrogen water—how this tiny molecule fights inflammation, selectively zaps harmful radicals, and keeps your cells playing in harmony. She'll be answering your top Qs: bottles vs. tablets, why timing's critical (drink it FAST), and how to turn your water into a smart hydrator. Ready to thrive? Let's flow.

Send us a textAs the global population ages, brain health is becoming a critical focus.What we must all realize is the role that exercise plays in our ability to maintain and improve cognitive function as we age. Our ability to move and play might just be the number one factor in slowing down the brain's age.The latest research continues to show that various exercise strategies positively impact brain health and overall cognitive function.Today on Strong By Design, we welcome Dr. Cody Sipe from the Functional Aging Institute (FAI). Cody is the co-founder of FAI along with Dan Ritchie. Their mission is to educate health and fitness professionals about the aging population and how exercise is key in the longevity of their client base. FAI, established in 2013, also provides these health experts with an online platform and live events for continuous learning and growth opportunities.Host of this week's episode is coach Chris Wilson, who is very familiar with FAI, having both a Brain Health Trainer and Mastering Movement Disorders certification through FAI. Discover how to unlock your brain's full power by enhancing cognitive function through exercise!Cody Sipe has an extensive background in the fitness industry with 20 years of experience as a personal trainer, fitness instructor, program director, exercise physiologist and club owner. He is currently an Associate Professor and Director of Clinical Research in the physical therapy program at Harding University.  “More and more people are realizing how important power training for older adults is.” -Dr. Cody Sipe  Time Stamps00:47 - Welcome to the Strong By Design podcast! 01:10 - Meet today's special guest, Dr. Cody Sipe co-founder of Functional Aging Institute (FAI) 04:31 - Discover the factors that contribute to improving our cognitive function 08:09 - Dr. Cody shares the story of how FAI was founded 10:12 - Discussing the significant impact you can have on a person's life and well-being 17:30 - Strategies for attracting people with strong expertise 20:16 - What is power training? 24:54 - Why is it crucial to build healthy exercise habits early in life 31:58 - Physical job vs Desk job: Which one wins? 35:48 - Dr. Cody highlights success stories from his program 38:17 - What challenges does physical therapy face with older adults 40:00 - Why should we treat exercise like kids do as we age 44:20 - How to combine technology with brain and body training 48:23 - Older adults' greatest fear revealed 51:26 - Follow Dr. Cody to learn more about his work and FAI 52:31 - Please share and leave ratings & reviews for the SBD podcast Resources:·         FunctionalAgingInstitute.com Connect with Dr. Cody:·         Instagram·         Facebook·         YouTubeSupport the showConnect w/ CriticalBench: Youtube Facebook Instagram CriticalBench.com StrongByDesignPodcast.com

Patricia Faust is a gerontologist specializing in brain aging and brain health.She has a Master's in Gerontological Studies from Miami University in Oxford Ohio. Patricia is certified as a brain health coach and received a certification in Neuroscience and Wellness through Dr. Sarah McKay and the Neuroscience Academy. My Boomer Brain is the vehicle Patricia utilizes to teach, coach, and consult about brain aging, brain health, and living a brain-healthy lifestyle.  Her book, The Boomer Brain, educates boomers on strategies to live a brain-healthy lifestyle and prevent Alzheimer's and dementia.https://www.seniorcareauthority.com/resources/boomers-today/

Believe the hype—art can transform your life.In this episode of Flow Radio, hosts Steven Kotler, Dr. Michael Mannino, and Ryan Wickes explore the powerful connections between creativity, longevity, and the future of human-AI collaboration. Tune in for a fresh look at how an “aesthetic mindset” influences aging, cognitive health, and the amount of flow in your life. Plus, get the low down on how partnering with AI can boost your creative potential far beyond a run-of-the-mill brainstorm. This is a must-listen for anyone wanting practical tips to lead a happier, healthier, and more creative life.  Join the discussion by leaving your questions for future Afterthoughts episodes in the comments. In This Episode: 01:36 Art vs. Altruism 04:06 Creativity and Longevity 06:19 The Role of AI in Future Jobs  11:10 Wisdom and Creativity as We Age 17:32 Brain Damage and Creativity 28:27 Hacking Creativity with Daydreaming35:12 Microflow and Daily Art Practice 42:08 Can AI Be Truly Creative? About The Guest: Steven Kotler is a New York Times-bestselling author, an award-winning journalist, and the co-founder and executive director of the Flow Research Collective. He is one of the world's leading experts on human performance. He is the author of eleven bestsellers (out of fourteen books), including The Art of Impossible, The Future is Faster Than You Think, Stealing Fire, The Rise of Superman, Bold and Abundance. His work has been nominated for three Pulitzer Prizes, translated into over sixty languages, and has appeared in over 110 publications, including academic journals such as Neuroscience and Biobehavioral Reviews and Psychophysiology, and mainstream publications like The New York Times Magazine, Wired, Atlantic Monthly, Wall Street Journal, TIME, and the Harvard Business Review. Dr. Michael Mannino is the Director of Programs at the University of Miami's Institute for Data Science and Computing, focusing on AI projects across various domains. He holds a Ph.D. in neuroscience and a Master's in philosophy, with expertise in embodied cognition, critical thinking, and the philosophy of mind. As a professor of philosophy and ethics for over a decade, Michael integrates his academic background with a passion for peak performance, flow science, and the mind-body connection. He is also an athlete, musician, and avid learner, and serves on the Singularity University Miami Chapter. Episode Resources: Book: Your Brain on Art: How the Arts Transform Us by Susan Magsamen and Ivy Ross Book: The Mature Mind: The Positive Power of the Aging Brain by Gene Cohen Book: The Wisdom Paradox: How Your Mind Can Grow Stronger As Your Brain Grows Older by Elkhonon Goldberg Article: Eric Kandel's Research on Aesthetic Experience Podcast: John Kounios on Mood and Creativity  Flow Radio Is Presented By Flow Research Collective Flow Research Collective is a leading neuroscience research and training company. If you're interested in learning the science-backed techniques we used to train top executives at Facebook, Audi and even the Navy SEALs, click the link here: https://www.flowresearchcollective.com/zero-to-dangerous/overview⁠⁠ ‍ Follow Flow Research Collective: YouTube: ⁠https://www.youtube.com/@flowresearchcollective⁠ Instagram: ⁠https://www.instagram.com/flowresearchcollective⁠ LinkedIn: ⁠https://www.linkedin.com/company/flowresearchcollective⁠ X: ⁠https://twitter.com/thefrc_official⁠ Facebook: ⁠https://www.facebook.com/flowresearchcollective⁠ Spotify: ⁠https://open.spotify.com/show/6RQY0d5rdlEiinHEtfWy6A⁠ Website: ⁠https://www.flowresearchcollective.com⁠ ‍ Flow Research Collective was founded by Steven Kotler, one of the world's leading experts on human peak performance. He is an award-winning journalist and author with over ten bestselling books.

Send us a textIn today's podcast, we will meet Jerry Wiles, a choice servant of God who is making a significant contribution to the cause of Christ in encouraging Christians to age well for the sake of the Gospel. Listen well to his story, learn through his life challenges, and take notes on his wisdom about finishing well.Learn more about him at Jerry Wiles at Jerry Wiles — James Houston Center or Jerry Wiles - Speakers Bureau | Leadershipbooks.comEmail us: Hal@finishingwellministries.orgFollow us on Facebook: https://www.facebook.com/finishingwellministriesSupport Our Ministry: https://www.finishingwellministries.org/donateAre there biblical principles to help us understand how to finish well?Join Dr. Habecker LIVE on ZOOM for a greater understanding of the SEVEN Essentials to Finishing Life Well: https://www.finishingwellministries.org/upcoming-eventsThanks for listening as we all strive to live and finish life well!

In this episode of Collective Insights, Dr. Greg Kelly hosts Dr. Heather Sandison, highlighting her profound impact on the field of dementia care and the launch of her new book, "Reversing Alzheimer's: The New Toolkit to Improve Cognition and Protect Brain Health." Dr. Sandison shares insights from her extensive experience, covering topics like holistic interventions for the aging brain, the significance of personalized medicine, and her pioneering work at Marama, the innovative elder care facility she founded.Sponsored by Qualia Mind: qualialife.com/benangel Use code benangel when you shop Qualia Mind for 15% off your order. Get in touch. Instagram: https://www.instagram.com/qualialife. Facebook: https://www.facebook.com/qualialife. Email: support@qualialife.com.

Welcome to another enlightening episode of Next Steps 4 Seniors: Conversations on Aging! In this episode, your host Wendy Jones sits down with the esteemed Dr. Ana Daughtery, Assistant Professor and Director of the Aging Brain Study at Wayne State University, to demystify the aging brain and distinguish it from Alzheimer's Disease. In this episode, you'll discover: The Aging Brain vs. Alzheimer's: Learn the key differences between the natural aging process of the brain and the pathological changes seen in Alzheimer's Disease. What Improves with Age: Contrary to popular belief, some cognitive functions actually improve as we age. Dr. Daughtery highlights these positive aspects of brain aging. Identifying Decline: Understand the signs of cognitive decline and how to differentiate between normal aging and potential dementia-related conditions. Taking Action: Get practical advice on what steps to take if you suspect a loved one is experiencing a dementia-related decline. Hormones and Aging: Explore how menopause and hormonal changes impact brain health in women. The Aging Brain Study: Discover what the Aging Brain Study entails, how you can participate, and how to get more information about your own brain health. Don't miss this episode if you want to gain valuable insights into brain health as you age and understand the critical differences between normal aging and Alzheimer's Disease. Tune in for expert advice, practical tips, and empowering information to help you navigate the journey of aging with confidence. Episode Resources: Listen to Next Steps 4 Seniors: Conversations on Aging wherever you get your podcast or Website: NextSteps4Seniors and Conversations on Aging Conversations On Aging: Facebook and Instagram Questions, Comments, or Suggestions: 248.652.5010 or hello@nextsteps4seniors.com   Website: Healthy Aging Brain Laboratory Dr. Ana DaughertySee omnystudio.com/listener for privacy information.

In this episode of Next Steps 4 Seniors: Conversations on Aging, host Wendy Jones is joined by Dr. Ana Daugherty, Director of the Detroit Aging Brain Study (DABS) at Wayne State University's Cognitive Neuroscience of Aging Lab. Together, they explore the intricate journey of how our brains change as we age and what we can do to maintain cognitive health. Key Topics Covered: Research on the Aging Brain: Dr. Daugherty shares insights from her research on how aging affects memory and problem-solving skills. Motivators for Brain Health: Discover the key motivators for taking proactive steps to care for our brains. Typical Aging vs. Cognitive Decline: Understanding what normal aging looks like and how it differs from cognitive decline. Brain Development and Aging: A look into the process of brain development and the changes that occur as we age. Anatomy of the Brain: Exploring the structure of the brain and its functions. Impact of Education and Career Choices: How our educational and career paths influence brain health. Role of Hobbies and Activities: The importance of engaging in hobbies and activities for cognitive well-being. Cognitive Engagement: Why it is crucial to keep our minds actively engaged. Stress and the Aging Brain: The effects of stress on cognitive health and strategies to manage it. Mindfulness and Diet: How mindfulness activities and a healthy diet can positively impact brain aging. Metabolic Diseases and Brain Health: Why metabolic health is essential for maintaining cognitive function. Lifestyle Changes for Brain Health: Practical tips for lifestyle changes that support brain health. Exercise for Cognitive Health: The roles of anaerobic and aerobic exercise in keeping our brains and bodies healthy. Skeletal and Muscular Health: How maintaining physical health supports cognitive function. Join Wendy and Dr. Daugherty for a comprehensive discussion that sheds light on the aging brain and offers actionable strategies to keep your mind sharp and healthy. This episode is packed with valuable information for seniors and their families who are committed to aging well. Tune in now to learn how to nurture your brain health through every stage of life. Episode Resources: Listen to Next Steps 4 Seniors: Conversations on Aging wherever you get your podcast or Website: NextSteps4Seniors and Conversations on Aging Conversations On Aging: Facebook and Instagram Questions, Comments, or Suggestions: 248.652.5010 or hello@nextsteps4seniors.com   Website: Healthy Aging Brain Laboratory Dr. Ana DaughertySee omnystudio.com/listener for privacy information.

Aging may be on your mind this week. And it's an often overlooked aspect of planning for retirement. Coleen T. Murphy, a leading scholar of aging, and the author of How We Age: The Science of Longevity, details how recent research on model systems, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging, This research is helping us understand the fundamental biological rules that govern aging - and it may be bringing us closer to extending healthspans and slowing the effects of aging. She joins us here in Princeton, New Jersey. __________________________ Bio Coleen T. Murphy is professor of genomics and molecular biology at Princeton University. She is director of Princeton's Glenn Foundation for Research on Aging and director of the Simons Collaboration on Plasticity in the Aging Brain. She is director of the Paul F. Glenn Laboratories For Aging Research at Princeton. Murphy completed a B.S. with honors in biochemical and biophysical sciences at the University of Houston and earned a Ph.D. at Stanford University. She was awarded a graduate fellowship at Howard Hughes Medical Institute and completed her postdoctoral work at the University of California, San Francisco. ___________________________ For More on Coleen T. Murphy How We Age: The Science of Longevity ___________________________ Podcast Episodes You May Like Why We Remember – Charan Ranganath How Not to Age – Dr. Michael Greger The Mindful Body – Ellen Langer ___________________________ Wise Quotes On Why We Age "I think if the better question is why wouldn't we age? Like in the entire universe, entropy is at work. So things fall apart and unless you put in energy to repair them, those things will fall apart. So we're no different, but just we're better at repairing all of our cells and tissues and everything else when we're young, right? My kids, if they get a cut, it heals up in like two days. And if I do, it doesn't. So we see those repair processes decline with age. And so that's really why we age because the amount that our body's put into repair actually gets overwhelmed at some point." On Cognitive Aging "So, by studying processes that change with age, my lab is extremely interested in cognitive aging. So we want to make that extend as long as possible. Even if it didn't extend lifespan, if we found a mechanism to maintain your cognitive function as long as possible, that would be super valuable for all of us. And so, that's what we're talking about when we're talking about healthspan. A lot of these age -related diseases that we care about in humans and then we understand the molecular mechanisms so that we can find ways to extend that in humans as well...Can we actually extend the you know the time of normal cognitive function? And it turns out we've been able to uncover pathways that do control that. So I'm really excited about some work that we did where we you know we found some we found a genetic pathway where if we flipped on just one protein made it more active in one neuron of the cell. Admittedly they have hardly any neurons - they have only 302. But this particular neuron is one that's really important for regulating their memory and we turn that on a super old worm and it rescued their memory. Nobody really cares until you show it in a mouse. And so we collaborated with friends of ours at UCSF and they put in into the hippocampus so the brain of the two -year -old mice. So that's like a 75 to 80 year old person. They put in the same activated protein in these it. rescue their memory. So that shows that we can use these pathways to find something in worms and apply it to mammals. And by the way, that protein is exactly the same in mice and humans. So that gives us sort of a way into this problem where we could start to address it pharmaceutically. So that's an example. I don't think it's the only way.

While Republican candidates in many states downplay their opposition to abortion, the most vehement wing of the movement, which helped overturn Roe v. Wade — those who advocate prosecuting patients, outlawing contraception, and banning IVF — are increasingly outspoken. Meanwhile, some state legislatures continue to advance new restrictions, like a proposal moving in Louisiana to include abortion medications mifepristone and misoprostol on the list of the most dangerous drugs. Alice Miranda Ollstein of Politico, Rachel Roubein of The Washington Post, and Joanne Kenen of the Johns Hopkins schools of public health and nursing and Politico Magazine join KFF Health News' Julie Rovner to discuss these stories and more. Also this week, Rovner interviews Shefali Luthra of The 19th about her new book on abortion in post-Roe America, “Undue Burden.” Plus, for “extra credit” the panelists suggest health policy stories they read this week that they think you should read, too: Julie Rovner: The 19th's “What Happens to Clinics After a State Bans Abortion? They Fight To Survive,” by Shefali Luthra and Chabeli Carrazana. Alice Miranda Ollstein: Stat's “How Doctors Are Pressuring Sickle Cell Patients Into Unwanted Sterilizations,” by Eric Boodman. Rachel Roubein: The Washington Post's “What Science Tells Us About Biden, Trump and Evaluating an Aging Brain,” by Joel Achenbach and Mark Johnson. Joanne Kenen: ProPublica's “Toxic Gaslighting: How 3M Executives Convinced a Scientist the Forever Chemicals She Found in Human Blood Were Safe,” by Sharon Lerner; and The Guardian's “Microplastics Found in Every Human Testicle in Study,” by Damian Carrington. Hosted on Acast. See acast.com/privacy for more information.

Coleen T. Murphy, Ph.D is Director, Lewis-Sigler Institute for Integrative Genomics,  James A. Elkins, Jr. Professor in the Life Sciences, Department of Molecular Biology, and LSI Genomics, Princeton University. She is also Director, Paul F. Glenn Center for Aging Research at Princeton and Director of Simons Collaboration on Plasticity and the Aging Brain. As a researcher, Coleen studies aging and the quantitation of “quality of life with age,” including the decline of cognitive and reproductive capacities with age. She is author of How We Age: The Science of Longevity. It is surprisingly readable and understandable. Coleen has had her own lab since 2005. She finds society's obsession with nutrition and dieting limiting for her research and has, instead, questioned what else can we do to preserve our health and cognitive aging. She has won numerous awards for her research including being named a Pew Scholar. Coleen was awarded the New Innovator, Transformative R01, and two Pioneer awards from the NIH Director's office. Effective research stems from knowing the right questions to ask. Coleen MurphyConnect with Coleen:Email: ctmurphy@princeton.eduPrinceton: http://www.molbio1.princeton.edu/labs/murphy/ ORCID: 0000-0002-8257-984XBook: How We Age: The Science of Longevity(AddLink)

We all know aging comes with cognitive challenges, but how early do they start? Sometimes, I forget my email password or where I put my car keys. Should I be worried? Dr. Nicole Byers came by to give us some fascinating answers, including the magical age when it can be beneficial to consume MORE calories. With a Ph.D. in clinical psychology and a dissertation focused on the aging brain, she's written extensively about brain health for Psychology Today. A neuropsychologist, TEDx speaker, and CEO of Rocky Mountain Neurosciences in Calgary, Canada, her passion is helping women in leadership rewire the unhelpful brain defaults that keep them stuck so they can take significant steps in their careers without getting in their own way or burning out. We all want to know how to keep our brains healthy for as long as possible. Who better to ask than someone who has dedicated her life to the topic? Stick around for some pearls of wisdom from Dr. Nicole Byers. Learn more about your ad choices. Visit megaphone.fm/adchoices

Episode #199 In this week's episode, Terri returns to a topic that she brought up previously to share some more information that could be helpful for us all. She went back to learn more about neurobics after a reference to this topic during another episode. Here is your opportunity to quickly learn about some pretty simple ways to affect your neuronal health and growth. If you would like a quick reminder of some simple neurotic exercises you can do, this guide is a good starting point: https://www.ageuk.org.uk/bp-assets/globalassets/hertfordshire/documents/activities--events/neurobic-exercise-guide.pdf Please consider helping us make more episodes by supporting Daisy on Patreon. https://bit.ly/MondayMindsetPatreon If you have enjoyed listening to this episode, please leave us a review on iTunes or whichever platform you listen on. It really helps new people hear about the podcast. Connect with and follow us on Facebook, Instagram and YouTube: https://bit.ly/MondayMindsetFB https://bit.ly/MondayMindsetIG https://bit.ly/MondayMindsetYT

The standard story of old age is a period of cognitive decline. 86% of Americans seem to agree with this story. They think 81 year old President Biden is too old to serve another term as. And another 62% think the same of 77 year old Donald Trump. But is this standard story of the aging brain wrong? Do some of our cognitive capacities actually improve in old age? Do we actually become more cognitively and mentally capable of leadership as we grow older? The Agenda looks at the science of the aging brain.See omnystudio.com/listener for privacy information.

If Joe Biden and Donald Trump are on the ballot in November, they'll be the oldest presidential candidates in U.S. history. How does age affect our memory, cognition, and even the ability to be president? About: On Point is WBUR's award-winning, daily public radio show and podcast. Every weekday, host Meghna Chakrabarti leads provocative conversations that help make sense of the world.

About Guy Odishaw Guy Odishaw is the founder of Bhakti Wellness Center, one of the largest, most diverse, integrative medicine clinics in the country. Co-founder of the first integrative student health clinics in the country at the University of Minnesota. Cofounder of Bhakti Brain Health Clinic - Neuroimaging & Neuromodulation. Cofounder of Minnesota Bredesen Clinic - Dementia Prevention & Treatment Co-founder of CerebralFit Brain Training, a Nutraceutical, Electroceutical, company. Guy's 30 years of clinical experience specializing in treatment resistant chronic pain, traumatic brain injury and psycho-emotional trauma informs his approach to brain health. Additionally, his 20+ years as meditation instructor and facilitator of courses on personal growth helped him understand how to support clients through the potent changes arising from Neurotherapy. Brain training does not only alleviate unwanted symptoms it often also positively changes one's whole sense of self and relationship to the world around them.   What We Discuss In This Episode In this episode, we talk about Guy's favorite subject – the treatment and prevention for neurodegenerative diseases, for example, dementia, Parkinson's, macular degeneration. With his general area of expertise being in Bioelectric Medicine and brain health, he remarks that although it's about brain healthy, they treat the whole body. The Aging Brain and anxiety. Cracking the longevity code & living better & longer with regenerative medicine Dementia unraveled -  effective strategies for treatment & prevention Shedding light on healing: the science and benefits of infrared light therapy Sparking Brain Health: Exploring the Power of Bioelectric Medicine, Neuromodulation, & Microcurrent Therapy   Free Resource from Guy Odishaw Free 15 min consult: https://www.cerebralfit.com   Connect With Guy Odishaw Website: https://www.cerebralfit.com Facebook: https://www.facebook.com/cerebralfit Instagram: https://www.instagram.com/cerebralfit/ LinkedIn: https://www.linkedin.com/in/guyodishaw/   Connect with Lynne: If you're looking for a community of like-minded women on a journey - just like you are - to improved health and wellness, overall balance, and increased confidence, check out Lynne's private community in The Energized Healthy Women's Club. It's a supportive and collaborative community where the women in this group share tips and solutions for a healthy and holistic lifestyle. (Discussions include things like weight management, eliminating belly bloat, balancing hormones, wrangling sugar gremlins,  overcoming fatigue, recipes, strategies, perimenopause & menopause, and much more ... so women can feel energized, healthy, and lighter, with a new sense of purpose. Website:  https://holistic-healthandwellness.com Facebook: https://www.facebook.com/holistichealthandwellnessllc The Energized Healthy Women's Club:  https://www.facebook.com/groups/energized.healthy.women Instagram: https://www.instagram.com/lynnewadsworth LinkedIn:  https://www.linkedin.com/in/lynnewadsworth   Free Resources from Lynne Wadsworth: How to Thrive in Menopause:   MENOPAUSE Messing Up your life?  Maybe you're seeing the number on the scale creep higher and higher and you're noticing your usual efforts to lose weight aren't working. Then there's the hot blazes, night sweats, and sleeping fitfully, not to mention that you're fighting tears one moment, raging the next, and then, the shameful guilt sets in because you've just blasted your partner – for nothing…again! Learn how to successfully and holistically navigate perimenopause and full-blown menopause, and even reconcile all the hormonal changes and challenges that go along with it. You'll be feeling energized, healthier, and more in control so you can take on your day confidently and live life joyfully – even in menopause. I've got this FREE solution tool for you.  Download my guide here: https://holistic-healthandwellness.com/thrive-through-menopause/   Grab Your Opportunity For a Free Call with Lynne: Would you love to be successful focusing on improved health & wellbeing in 2024?  Maybe you'd like to increase your energy levels, reduce or maintain a healthy weight, ditch the brain fog & belly bloat. Or maybe you'd love some more strategies to help transform you into a “magnificent midlifer” who's fully energized - charged & ready to start each new day with anticipation and & joy, Or maybe you have some illness you've been facing and it's compounded by menopause. I'd love to chat.  Contact me to schedule your FREE HEALTHY YOU Clarity Call. We'll discuss where you're at on your journey and how I can help you successfully navigate your life through this "midlife season" with grace and ease.  Schedule your time >>here

As researchers continue their search for the fountain of youth, they're turning their attention to an unlikely source: worms. Coleen T. Murphy is professor of genomics and molecular biology at Princeton and director of both the university's Glenn Foundation for Research on Aging and the Simons Collaboration on Plasticity in the Aging Brain. She joins host Krys Boyd to discuss how worms and other simple organisms offer insights into the aging process and how we might slow it down. Her book is “How We Age: The Science of Longevity.”

We all know the physical benefits of exercise, but today we talk about the brain benefits. How does exercise impact depression and anxiety? How can exercise help keep our brains young? Should our exercise habits change depending on our mental health? Today, we speak to Dr. Jennifer Heisz, Professor of Kinesiology at McMaster University. Check out her book Move the Body, Heal the Mind. To get weekly episodes, come join the Foodie Fam: https://www.patreon.com/FWNTT Check out our book! https://read.macmillan.com/lp/food-we-need-to-talk/ Chat with us on IG! https://www.instagram.com/foodweneedtotalk/?hl=en Be friends with Juna on IG and Tiktok! https://www.instagram.com/theofficialjuna/ https://www.tiktok.com/@junagjata