Podcasts about Harvard Medical School

Work with the Muscle Intelligence Team: https://muscleintelligence.com/apply Most men who suspect their testosterone is low get a blood test, get told the number is normal, and get sent home still exhausted, still soft in the middle, still wondering what happened to the guy they used to be. Dr. Abraham Morgentaler has spent thirty-five years proving that those men are not imagining it. He is a urologist on the Harvard Medical School faculty, the physician who overturned the belief that testosterone causes prostate cancer, and the author of Testosterone for Life and The Truth About Men and Sex. He was treating low testosterone before almost anyone in American medicine was willing to touch it. In this conversation he explains why the number your doctor is reading may be the wrong one, why symptoms track a completely different measurement, and how a single 1941 paper convinced medicine to withhold testosterone from men for five decades. He also takes apart the estrogen panic driving most TRT protocols today, explains why he refuses to make overweight men earn treatment by losing weight first, and traces exactly where the story about testosterone and heart attacks came from. If you have ever been told your labs look fine, this is the episode that explains what was actually measured. KEY TAKEAWAYS Why two men with identical total testosterone can have completely different symptoms, and which number separates them The reason 98% of your circulating testosterone may not be doing anything for you What he found when he surveyed 25 laboratories about their definition of "normal," and why the answer should worry you Why blocking estrogen on testosterone therapy can cost you the exact result you started therapy to get The reason he treats out-of-shape men before asking them to lose a pound, and why 95% of his colleagues disagree CONNECT WITH DR. ABRAHAM MORGENTALER Website – https://t4leducation.com X – https://x.com/DrMorgentaler Book – The Truth About Men and Sex Book – Testosterone for Life

Dr. Lucy McBride is a primary care physician and co-founder of the Ackerly McBride Group in Washington, DC. For over 25 years, she has practiced evidence-based, relationship-centered medicine. A graduate of Princeton and Harvard Medical School, with a master's degree in Pharmacology from Cambridge as a Fulbright Scholar, she completed her internal medicine residency at Johns Hopkins Hospital. She writes the weekly newsletter Are You Okay? and hosts the podcast Beyond the Prescription. Her work has appeared in The Atlantic, The Washington Post, and USA Today. She has contributed to CNN, MSNBC, and PBS, advocating for a holistic, patient-centered approach to health. Her upcoming book Beyond the Prescription will be released August 11, 2026.In this conversation, we discussed how health isn't just about getting answers but about asking the right questions, what primary care physicians are doing for their patients in an ideal world vs. what is actually happening, why doctors should treat the whole patient and not just a set of symptoms, and her upcoming book Beyond the Prescription which includes a 5 step process for taking charge of your health.Connect with Lucy: Instagram | Website | Substack | Buy the Book If you're looking to unleash your potential, find your personal, professional, or political fire, and to connect with a community who is doing the same, click here to learn more. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit shannonwatts.substack.com/subscribe

In this episode, I sit down with Dr Peter Wayne, Director of the Osher Center for Integrative Health at Harvard Medical School and Brigham & Women's Hospital. A prolific researcher of the science of body-mind practices, Peter is the author of The Harvard Medical School Guide to Tai Chi (2013) and over 200 scientific papers. But he has also been a practitioner and instructor of taiji and qigong for over 45 years, and is the founder of the Tree of Life Tai Chi Center outside of Boston. Together we explore the intersection of science and practice, as well as the bridges he has been building for decades between them. Along the way, we discuss reconciling reductionism with systems thinking, Peter's ecological way of speaking about the body, and whether or not one should mention qi in a scientific paper. If you want to hear scholars and practitioners engaging in multidisciplinary conversations about Asian healing and mystical traditions, then subscribe to Black Beryl wherever you get your podcasts. Also check out our members area on Substack (blackberyl.substack.com), as each episode our guests share downloadable PDFs of articles, book chapters, and other materials for you.One last thing: we are planning an “Ask Me Anything” episode coming up soon, so reach out via Substack or my website, piercesalguero.com, and let me know your questions. Ok, on with the show!Resources mentioned in this episode:* Osher Center for Integrative Health* Ted Kaptchuck, The Web That Has No Weaver (2000)Subscribe on blackberyl.substack.com to unlock our members-only benefits, including these PDFs of Peter's publications:* Wayne et al., “A Systems Biology Approach to Studying Tai Chi, Physiological Complexity and Healthy Aging” (2013)* Wayne et al., “Can Tai Chi and Qigong Postures Shape Our Mood? Toward an Embodied Cognition Framework for Mind-Body Research” (2018)* Wayne et al., “Integrative Medicine Is a Good Prescriptionfor Patients and Planet” (2019)* Wayne et al., “The Science of Tai Chi and Qigong as Whole PersonHealth” (2025) Get full access to Black Beryl Podcast at blackberyl.substack.com/subscribe

Description:  Hosts Roz and Dr. Sanchez-Fueyo are joined by Alessia Giarraputo to discuss the key articles of the August issue of the American Journal of Transplantation. Alessia Giarraputo is a postdoc research fellow at Mass General Hospital and Harvard Medical School [3:38] Donor-reactive clonotypes are overrepresented in the urinary T cell repertoire during kidney transplant rejection and show distinct dynamics in the circulation [13:57] Organ-specific differences in the epidemiology of cytomegalovirus infections in high-risk (cytomegalovirus donor seropositive, recipient seronegative) solid organ transplant recipients with prolonged follow-up: A 10-year experience [22:17] Immune checkpoint inhibitors after liver transplantation: The role of immunosuppressive management [28:34] Expert consensus on the use of immune checkpoint inhibitors in the liver transplant setting: Guidance from the Liver Transplant Committee of the Italian Association for the Study of the Liver (AISF) [33:50] Outcomes of kidney transplants from pediatric donors with acute kidney injury

Can artificial intelligence restore humanity to my patient interactions? In this episode, Dr May Lin and Dr Brent Sugimoto explore how ambient scribing and smarter administrative tools free physicians to be truly present with their patients, allowing technology to become a bridge in patient care rather than a barrier. Our guests also tackle the ethical and policy dimensions of how AI affects family medicine in both the exam room and the classroom. They identify the current moment as an opportunity for residency programs to shape how AI is used in family medicine, emphasizing that if today's residents are not trained to use AI tools ethically and wisely, their future patients may miss out on the benefits of technology-assisted care.Hosted by Omari A. Hodge, MD, FAAFP and Jay-Sheree Allen Akambase, MDCopyright © Society of Teachers of Family Medicine, 2026Resources:Blood in the Machine: The Origins of the Rebellion Against Big Tech by Brian MerchantArtificial Intelligence and Machine Learning for Primary Care Curriculum (AiMPC) CourseEthical Use of AI in the Family Medicine Clinic - STFM WebinarAn Opportunity to Thrive - AI in Family Medicine - STFM PodcastAI Deep Dive Summer Series Episode 1: Integrating AI into Family Medicine Curriculum Design - STFM PodcastAI Deep Dive Summer Series Episode 2: The Promises and Pitfalls of AI in Residency Assessment - STFM PodcastGuest Bio:May Lin, DODr Lin is board certified in Family Medicine and Osteopathic Manipulative Medicine (OMM). She practices at Amazon/One Medical where she also serves as the Director of Academic Development. A graduate of Harvard Medical School's Executive Education Course on AI in Healthcare, Dr. Lin serves on the American Association of Colleges of Osteopathic Medicine's (AACOM) Technology Task Force, Touro University's AI Task Force, and the American Osteopathic Information Association's (AOiA) national steering committee. As an Osteopathic Health Policy Fellow, Dr. Lin blends policy interest with leadership experience in healthcare technology and medical education. Dr. Lin is passionate about advancing medical innovation giving patients increased access, decrease cost and improved quality in high touch, technology forward medical care. Integrating primary care, medical innovation, healthcare technology, and healthcare policy are key attributes to supporting primary care and elevating our next generation for sustainable primary care practice and delivery.Brent Sugimoto, MD, MPHDr Sugumoto is program director of the LifeLong Medical Care Family Medicine Residency Program and a Family Physician who specializes in HIV medicine. He currently serves as co-chair of the AAFP/Rock Health “Advancing AI and Digital Health for Primary Care Initiative.” Brent ventured into artificial intelligence after the birth of his first child—when parenthood made him rethink the boundaries of his professional and personal lives—and co-founded a startup called Decoded Health, which leveraged technology from DARPA to build tools to make primary care sustainable. Since then, Brent has worked to increase family medicine's engagement in AI/ML as a potentially transformative and disruptive technology through physician education and policy work within the specialty. Brent is excited to be a member of this task force, as he believes health technology literacy will be a critical competency for future family physicians. He uses ambient scribing with moderate success in his own practice.Link:https://www.stfm.org/stfmpodcast082026 

In this episode, my guest is Dr. Sean Cain, PhD, a Harvard Medical School-trained expert in the impact of light on the human circadian system, a Matthew Flinders Professor at Flinders University, and Co-Founder and CEO of Circadian Health Innovations. Today, he discusses how people differ more than fiftyfold in how sensitive their circadian systems are to evening light, that nearly half of modern homes are bright enough at night to suppress melatonin by fifty percent, and that most of us have no conscious awareness of any of it. We discuss the large observational studies he and his team have published linking bright days and dark nights to depression, type 2 diabetes, cardiovascular disease, and mortality, as well as his research on impaired light sensitivity in depression and why the amplitude of your circadian rhythm may matter more than its timing. We also discuss MiEye, the wearable light sensor his team developed, and practical changes to home and daytime lighting that anyone can make tonight.CLICK HERE FOR THE FULL SHOWNOTESThis includes all other resourcesSponsor: Brighter Lamphttps://getbrighter.com/?sjram=P2jrTbowzJOdCode: JONATHANJ   Subscribe to the newsletter: https://jonathanjarecki.substack.com/?utm_campaign=profile_chipsTimestamps 00:00 Intro03:54 Dr. Sean Cain04:42 Dr. Cain's Love for Science and Research10:25 Understanding Circadian Rhythms: Anatomy and Function10:56 Setting the stage: Circadian Biology, Rhythms, SCN, ipRGCs16:20 Light, Circadian Entrainment, Mechanisms19:57 High Sensitivity and Interindividual Variability in the Response of the Circadian of the Human Circa22:02 Individual Sensitivity to Light and Circadian Disruption27:22 Home Lighting, Sunset, LEDs, Fluorescents, Incandescents27:37 Home Lighting and Its Effects on Circadian Health33:46 Tools: circadian friendly home lighting39:24 Population health outcomes; UK BioBank39:29 Psychiatric Disorders47:52 SPONSOR: Brighter Lamp49:34 The Link Between Light Exposure and Mental Health01:04:18 Light Exposure and Longevity: Key Findings01:09:45 The Importance of Daylight for Health01:17:41 Understanding Circadian Rhythms and Light Exposure01:17:52 The Impact of Light on Mood and Self-Perception01:23:39 Innovations in Circadian Health: My Eye Device01:34:15 Jet Lag Management and the Jet Lag App01:39:09 Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Social Media, Substack Newsletter

In this episode, Dr. David Puder speaks with Robert Drozek, clinical director of the Mentalization-Based Treatment (MBT) Clinic at McLean Hospital and teaching associate at Harvard Medical School, about practical Mentalization-Based Therapy techniques to improve clinical outcomes in borderline personality disorder (BPD), OCD, and narcissism. Drozek explains the "What, Why, and How" model of mentalizing, how to address psychic equivalence (rigid certainty), pretend mode, and teleological thinking, and offers concrete strategies clinicians can use in session and assign as between-session work to help patients reconnect with difficult emotions, reduce intellectualization, and develop more flexible, reflective ways of understanding themselves and others. Link to blog Link to YouTube video

Jerry Avorn is a professor of medicine at Harvard Medical School and the codirector of the Program on Regulation, Therapeutics, and Law at Harvard Medical School and Brigham and Women's Hospital. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. J. Avorn. Products That Pose Health Risks — Can Litigation Protect Us When Government Fails? N Engl J Med 2026;395:421-423.

How you feel on Sunday night tells you something real about your relationship with work. Amy Leneker, the author of Cheers to Monday, calls it one of the most honest assessments we have, and she would know. Seven weeks into medical leave after a panic attack, she sat in a doctor's office, got handed a questionnaire, and could not answer a question about what she did for fun. In this conversation, Amy walks through what she learned from that unraveling and the research that followed. She explains the difference between the stress that helps you perform and the stress that wears you down, and why leaders and their teams so often talk past each other on exactly that point. She shares the zero-to-10 question that opens up a conversation about stress without putting anyone on the spot, her three-step See, Sort, Solve method, and how to separate what you can control from what you cannot. There is a lot in here you can use this week if you lead people. Including one calendar trick involving a standing Friday appointment with Dr. Green. About our guest Amy Leneker is the founder and CEO of the Center for Joyful Work and the author of Cheers to Monday: The Surprisingly Simple Method to Lead and Live with Less Stress and More Joy, published by Wiley in 2026. The book debuted as the number one bestselling business book on the USA Today list. Amy spent more than two decades in leadership, including ten years in the C-suite, before burnout forced a different path. She has studied leadership at Yale, neuroscience at the NeuroLeadership Institute, and stress resilience at Harvard Medical School. She leads an annual national workforce study on stress and joy at work, has trained more than 100,000 people, and hosts the Less Stress, More Joy podcast. She and her family live in the Pacific Northwest. TIMESTAMPS 00:00 Intro and sponsor 02:10 The question in a doctor's office she could not answer 05:05 The signs she ignored for years 05:55 Why your Sunday night mood is honest data 07:10 Turning her own burnout into a literature review 09:35 Eustress and distress, and why leaders and teams talk past each other 11:40 The check engine light and the cost of waiting 13:20 See, sort, solve 15:25 The stress ruler and the zero to 10 question 19:40 Stress and joy are both contagious 20:45 Values that leave you out will burn you out 24:10 Sorting what you can control from what you cannot 26:45 Why the people quickest to offer help are the slowest to ask for it 28:50 Cancel a meeting 30:20 The Dr. Green calendar story 32:35 What leaders get wrong in uncertain moments 34:45 Stress thrives in isolation A QUICK GLIMPSE INTO OUR PODCAST Podcast: Transform Your Workplace, sponsored by Xenium HR Host: Brandon Laws In Brandon's own words: "The Transform Your Workplace podcast is your go-to source for the latest workplace trends, big ideas, and time-tested methods straight from the mouths of industry experts and respected thought-leaders." About Xenium HR Xenium HR is on a mission to transform workplaces by providing expert outsourced HR and payroll services for small and medium-sized businesses. With a people-first approach, Xenium helps organizations create thriving work environments where employees feel valued and supported. From navigating compliance to enhancing workplace culture, Xenium offers tailored solutions that empower growth and simplify HR. Whether managing employee relations, payroll processing, or implementing impactful training programs, Xenium is the trusted partner businesses rely on to elevate their workplace experience. Discover how Xenium can transform your workplace: Learn more Mentioned in this episode: Xenium HR Leadership Cohorts Connect with Amy Leneker: Website LinkedIn Cheers to Monday Connect with Brandon Laws: LinkedIn Instagram About Connect with Xenium HR: Website LinkedIn Facebook Twitter Instagram YouTube

In today's episode, we spoke with Paolo Tarantino, MD, PhD. Dr Tarantino is a breast medical oncologist and advanced fellow at Dana-Farber Cancer Institute and Harvard Medical School in Boston, Massachusetts.In our exclusive interview, Dr Tarantino discussed practice-informing data regarding antibody-drug conjugates in breast cancer that were presented at the 2026 ASCO Annual Meeting, including the use of fam-trastuzumab deruxtecan-nxki (T-DXd; Enhertu) plus pertuzumab (Perjeta) for first-line treatment of HER2-positive breast cancer based on findings from the phase 3 DESTINY-Breast09 trial (NCT04784715); updated safety data from the phase 3 DESTINY-Breast05 trial (NCT04622319) that indicated that T-DXd–associated interstitial lung disease is reversible with steroids, although radiation pneumonitis is non-reversible; and the phase 3 OPTIMA trial (ISRCTN42400492) results, which suggested that the PAM50 signature can identify patients who may not need chemotherapy, potentially sparing them from unnecessary treatment.

In today's episode, we spoke with Sara M. Tolaney, MD, MPH, about the FDA approval of sacituzumab govitecan plus pembrolizumab (Keytruda) or pembrolizumab and berahyaluronidase alfa-pmph (Keytruda Qlex) for the first-line treatment of adult patients with unresectable locally advanced or metastatic triple-negative breast cancer (TNBC) whose tumors express PD-L1 as determined by an FDA-authorized test. Dr Tolaney is chief of the Division of Breast Oncology and associate director of the Susan F. Smith Center for Women's Cancers and a senior physician at Dana-Farber Cancer Institute, as well as an associate professor of medicine at Harvard Medical School in Boston, Massachusetts.This regulatory decision was backed by findings from the phase 3 ASCENT-04/KEYNOTE-D19 trial (NCT05382286), in which the median progression-free survival among patients in the sacituzumab govitecan arm was 11.2 months (95% CI, 9.3-16.7) vs 7.8 months (95% CI, 7.3-9.3) among patients who received physician's choice of chemotherapy plus pembrolizumab (HR, 0.65; 95% CI, 0.51-0.84; P = .0009).In our exclusive interview, Dr Tolaney highlighted the significance of this approval, key data from ASCENT-04, and how the TNBC paradigm is shifting to accommodate this new regimen.

For this Managed Care Cast episode, The American Journal of Managed Care® (AJMC®) spoke with Anuraag R. Kansal, PhD, who leads health economics research at GRAIL, about his study, “State Medicaid Budgetary Implications of New Cancers," published in the July 2026 issue; it examined how new cancer diagnoses affected state Medicaid budgets. He conducted the study with Amanda C. Chen, PhD, of the USC Mann School of Pharmacy and Pharmaceutical Sciences, and David C. Grabowski, PhD, of Harvard Medical School. Kansal explained to AJMC that despite Medicaid's younger population, cancer remains the third-largest source of program spending. Most existing research had focused on commercial and Medicare populations rather than Medicaid specifically. Consequently, using de-identified CMS claims data, he and his team identified new cancer diagnoses, defined as no prior cancer evidence in the preceding 6 months, and compared spending, hospitalizations, and emergency department use between metastatic and non-metastatic cases. Kansal highlighted the core finding, which was that metastatic diagnoses were associated with significantly higher spending than non-metastatic diagnoses across most cancer types. Notably, health care utilization patterns were consistent between fee-for-service and capitated Medicaid states, suggesting that cost drivers stemmed from the disease itself, particularly the shift to systemic therapies once cancer spread, rather than from program administration models. Kansal pointed to the 4 cancer screenings recommended by the US Preventive Services Task Force, namely lung, breast, colorectal, and cervical, as opportunities to reduce late-stage diagnoses and their associated costs while noting that cancers without established screening protocols presented a distinct policy challenge. On balancing innovative treatment access with cost sustainability, he emphasized that Medicaid's state-by-state administration means that no single policy solution applied universally. Still, Kansal emphasized that earlier detection could offer states greater financial flexibility to support innovative therapies for patients with true clinical need. “Intervening earlier is one of the opportunities we might have to really make a difference,” he concluded.

In episode 83 of Going anti-Viral, Dr Steven Grinspoon joins host Dr Michael Saag to provide an update on guidelines for statin use in people with HIV based on results from the REPRIEVE trial. Dr Grinspoon is a Professor of Medicine at Harvard Medical School and a clinician in the Neuroendocrine and Pituitary Tumor Clinical Center and faculty member at the Massachusetts General Hospital. He is a clinical researcher who studies hypothalamic control of body weight and fat distribution in obesity and lipodystrophy with a focus on the metabolic and cardiovascular consequences of visceral fat accumulation. Dr Grinspoon is the author of more than 200 peer-reviewed publications and serves as the chief of the Massachusetts General Metabolism Unit and the director of the Nutrition Obesity Research Center at Harvard. Dr Grinspoon and Dr Saag discuss the latest findings from the REPRIEVE trial and provide updates on statin guidelines for people with HIV as well as providing insights into cardiovascular risk management. They discuss the safety and efficacy of statins and the role of cardiovascular risk calculators in clinical practice in addition to discussing the impact of low-density lipoprotein (LDL) cholesterol and inflammation on cardiovascular risk. Dr Grinspoon also offers his outlook for where further research is needed based on the outcomes of the REPRIEVE trial.0:00 – Introduction 1:33 – Overview of the REPRIEVE trial findings2:44 – Changes in statin guidelines for people with HIV 6:51 – Safety and efficacy of statins9:09 – Use of statins and diabetes risk11:16 – Cardiovascular risk calculators16:00 – Statin use and blood pressure17:14 – Impact of LDL cholesterol and inflammation on cardiovascular risk24:08 – Future directions in cardiovascular research for people with HIV  Resources:Going anti-Viral: Episode 56 – Cardiovascular Health in People with HIV – Dr Steven GrinspoonApple Podcasts:https://podcasts.apple.com/us/podcast/the-management-of-cardiovascular-health-in-patients/id1713226144?i=1000725697103 YouTube:https://youtu.be/297vweZ5bjQ  REPRIEVE Trial: https://www.reprievetrial.org/ __________________________________________________Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections.Going anti-Viral's host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences. Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.Follow Going anti-Viral on: Apple Podcasts YouTubeXFacebookInstagram...

Every day, roughly 100 Americans die in crashes caused by human drivers. Yet when a self-driving car hesitates at an intersection or makes the news for an unusual mistake, public trust can evaporate.In this special episode, Dr. Jonathan Slotkin reads his latest Noema essay exploring why we demand perfection from machines while accepting human error as inevitable. Drawing on lessons from medicine, psychology, and autonomous vehicles, he argues that the biggest barrier to safer technology is trust.You'll learn:Why humans judge machine mistakes differently than human mistakesWhat healthcare learned about the difference between being safe and feeling safeWhy autonomous vehicles may already be far safer than human driversHow public perception can slow the adoption of life-saving technologyWhat every AI company should learn about transparency and trust —About our guest:Dr. Jonathan Slotkin is Chief Medical Officer for Strategy & Growth at Geisinger, where he drives growth at the intersection of care delivery, insurance, and digital transformation. A practicing neurosurgeon, he previously served as Geisinger's associate chief medical informatics officer.Jon's current research and writing examine safety, trust, and adoption of autonomous systems in public life. His New York Times guest essay on self-driving car safety was entered into the Congressional Record. His writing regularly appears in Harvard Business Review, STAT, and Noema Magazine. He has authored more than 70 peer-reviewed scientific publications.Previously, as co-founder and chief medical officer of Contigo Health, he partnered with the nation's largest employers to reimagine care for their associates. He co-founded Scrub Capital, a clinician-powered venture capital firm, where he serves as a Partner. He completed neurosurgery residency at The Brigham and Women's Hospital, Harvard Medical School, where he served as chief resident.—This piece was commissioned, edited, and published by Noema Magazine. Noema publishes longform journalism exploring fresh ideas. To read this piece and others, head to noemamag.com.—

Charles Berde, MD, PhD, is the Sara Page Mayo Chair in Pediatric Pain Medicine and a Professor of Anaesthesia at Harvard Medical School. As a co-founder of the Pain Treatment Center at Boston Children's Hospital, he has spent decades at the forefront of pediatric analgesic pharmacology and the development of novel local anesthetics. His extensive translational research focuses on local anesthetic mechanisms and prolonged-duration formulations, making him a preeminent authority on the physiological impacts and safety profiles of these agents in neonates and children. A recipient of the Myron Yaster Lifetime Achievement Award from the Society for Pediatric Anesthesia, Dr. Berde brings unparalleled expertise to the discussion of managing and preventing local anesthetic systemic toxicity (LAST) within the high-stakes environments of the PICU and pediatric operating rooms.Guest Conflicts of Interest (COI)Algavita Bio: Collaborator/Developer of novel, prolonged-duration local anesthetics.Quiver Bioscience: Unpaid Scientific Advisor and co-PI on an NINDS-HEAL grant focused on rare disease pain treatments.Latigo Biotherapeutics: Scientific Advisor and recipient of past research support for novel analgesics development.Algos: Scientific Advisor for non-opioid analgesics development.Learning Objective: By the end of this podcast, listeners should be able to discuss an evidence-based and expert-guided approach to the management of local anesthetic systemic toxicity (LAST) in children.References:Patient and Doctor Reconcile for Greater GoodBerde CB. Toxicity of local anesthetics in infants and children. J Pediatr. 1993 May;122(5 Pt 2):S14-20. doi: 10.1016/s0022-3476(11)80004-1.McMahon K, Paster J, Baker KA. Local anesthetic systemic toxicity in the pediatric patient. Am J Emerg Med. 2022 Apr;54:325.e3-325.e6. doi: 10.1016/j.ajem.2021.10.021. Epub 2021 Oct 25. Lavonas et al. 2023 American Heart Association Focused Update on the Management of Patients With Cardiac Arrest or Life-Threatening Toxicity Due to Poisoning: An Update to the AHA Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2023 Oct 17;148(16):e149-e184. doi: 10.1161/CIR.0000000000001161. Epub 2023 Sep 18. Questions, comments or feedback? Please send us a message at this link (leave email address if you would like us to relpy) Thanks! -Alice & ZacSupport the showHow to support PedsCrit:Please complete our Listener Feedback SurveyPlease rate and review on Spotify and Apple Podcasts!Donations are appreciated @PedsCrit on Venmo , you can also support us by becoming a patron on Patreon. 100% of funds go to supporting the show.Please remember that all content during this episode is intended for educational and entertainment purposes only. It should not be used as medical advice. The views expressed during this episode by hosts and our guests are their own and do not reflect the official position of their institutions. If you have any comments, suggestions, or feedback-you can email us at pedscritpodcast@gmail.com.  You can also check out our website at http://www.pedscrit.com. Thank you for listening to this episode of PedsCrit!

Medical cannabis sits in a crowded space of strong claims, real risks, and uneven regulation. Dr. Peter Grinspoon joins Mike Vera for an honest conversation about what cannabis may help, what can harm, and what remains unknown, from rescheduling and unregulated hemp-derived products to dependence, CBD labels, sleep, and aging.A note before you listen: this conversation covers cannabis use and addiction. It is shared for educational purposes only and is not medical advice. If you are struggling or in crisis, support is available 24/7: in the US, call or text 988 (Suicide and Crisis Lifeline), or text HOME to 741741 (Crisis Text Line). Outside the US, contact your local emergency services or crisis line. If you or someone you know is struggling with substance use, SAMHSA's National Helpline is 1-800-662-HELP (4357).

Researchers from Mass General Brigham and Harvard Medical School published what is now the largest study of former NFL players ever conducted. They looked at nearly twenty thousand players who appeared in at least one NFL game between 1960 and 2019. The data is sobering: former NFL players were about four times more likely to die from neurodegenerative diseases than the general population. And while football has always been dangerous, the question is whether we can keep making it less dangerous without losing what makes it football. Scott & A discuss. — Slices is created by Scott Sigler and A B Kovacs — Produced by Steve Riekeberg — Production Assistance by Allie Press — Copyright 2026 by Empty Set Entertainment  Sometimes, maybe leave a little less on the field? The brain is elastic, or so they say. I'd like to give someone a piece of my mind using GoDaddy Promo Code CJCFOSSIG3 so's I can save big on my first year of a 3-year domain. Big like 99% big! Learn more about your ad choices. Visit megaphone.fm/adchoices

At Lifespan, our mission is to help you and your loved ones live your longest, healthiest lives while supporting medical research into breakthroughs to improve all lives. We're building the world's largest longevity community: Join us at https://lifespan.com. Follow us on YouTube, Apple, and Spotify for new Lifespan episodes every 2 weeks.                                __________________________________________ In this episode of Lifespan, Dr. David Sinclair, A.O., Ph.D. – Professor of Genetics at Harvard Medical School and pioneer in longevity research – explores the science of eye aging, vision loss, and emerging strategies to preserve vision throughout life. Dr. Sinclair shares an exclusive update on ER-100, including his team's successful restoration of vision in non-human primates and the launch of the world's first FDA-cleared age reversal human clinical trial. This Phase 1 clinical trial will evaluate the safety of epigenetic cellular restoration as a therapy. Additionally, drawing on decades of research, Dr. Sinclair explains why the eyes may offer one of the earliest windows into biological aging, how everyday factors such as sleep position, alcohol consumption, and intraocular pressure influence long-term eye health, and what the latest evidence reveals about nutrition, supplements, and the connection between the eyes and the brain. Whether you're interested in longevity, brain health, or protecting your eyesight, this episode provides an evidence-based look at the biology of vision and the future of regenerative medicine.                                __________________________________________ Partners of the Lifespan show help us keep this program freely available as an educational resource while also supporting medical research. We only collaborate with partners whose products are grounded in science and that our team has personally used for years. Our selected partners make it convenient for the Lifespan audience to access the tools and technologies featured in this episode - from exogenous fuel for neurons (Ketone-IQ), to wearables that track recovery, strain, and sleep (WHOOP), to smart devices that measure key health metrics such as visceral fat and muscle mass (Withings). If you'd like to learn more or try these tools: ○ Ketone-IQ: Get 30% off your first monthly order at https://ketone.com/lifespan or with code LIFESPAN ○ WHOOP: Get a free WHOOP band and one month of membership at https://join.whoop.com/LIFESPAN or with code LIFESPAN ○ Withings: Get 10% off smart health devices at https://withings.com/lifespan or with code LIFESPAN                                __________________________________________ Legal & Medical Disclaimers The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program. The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship.  Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ. From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual. Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research.   The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.

Many people know the term “bipolar disorder,” but few understand what mania actually looks like, how depression presents, or why recognizing the warning signs can be so difficult. In this episode, host Gabe Howard sits down with ADAA (Anxiety and Depression Association of America) Member expert Bruce M. Cohen, MD, PhD. Dr. Cohen is a psychiatrist, Harvard Medical School professor, and former president and psychiatrist-in-chief of McLean Hospital. Together, they break down the realities of bipolar disorder, including the differences between bipolar I, bipolar II, and cyclothymia. Listeners will learn: how some risk-taking behaviors could be warning signs how distinguishing bipolar from personality traits requires careful evaluation how caregivers need support and self-care to be effective They also tackle an important question: When is someone simply energetic, dramatic, or outgoing — and when could those traits point to a mental health condition? Using real-world examples and decades of clinical experience, Dr. Cohen explains how mental health professionals distinguish personality from illness. If you've ever wondered what bipolar disorder really looks like — or how to help someone who may be struggling — this episode is for you. We would like to thank McLean Hospital for providing educational support for this episode. “I've been doing this for 50 years and I've focused on psychotic disorders and bipolar disorders. [. . .] Most of them lead good lives and they're successful.” ~Bruce M. Cohen, MD, PhD Our guest, Bruce M. Cohen, MD, PhD, is the Robertson-Steele Professor of Psychiatry at Harvard Medical School and President/Psychiatrist-in-Chief Emeritus at McLean Hospital. Currently, as Director of the Program for Neuropsychiatric Research at McLean/Mass General Brigham, he leads a consortium using cell culture, genomic, pharmacologic, brain imaging, and clinical studies to increase understanding and develop new treatments for psychiatric disorders. This work is particularly focused on identifying inherent factors that might be modulated to reduce the risk of illness. Convergent evidence from these studies highlights key factors underlying risk for illness, prominently including abnormalities of energy production and brain cell growth and maturation. These abnormalities affect brain development, brain remodeling during adolescence, and brain repair with age. In addition, his work has documented evidence-based dimensional approaches for diagnosing psychiatric disorders that describe each person seeking treatment more accurately and thoroughly than standard diagnostic models. Collaborating investigators work at McLean, the Broad Institute of Harvard and MIT, and international sites. Following undergraduate studies at the Massachusetts Institute of Technology and graduate (molecular genetic) and medical studies at Case Western Reserve University, Dr. Cohen completed his residency training at McLean. He was co-founder of a Clinical Research Center, founding Director of McLean's Brain Imaging Center, and director of McLean's Residency Training Program, and a Vice President at McLean, before becoming President and Psychiatrist-in-Chief of the hospital. Under his leadership, McLean, which was struggling financially, established over 30 new programs, became financially stable and grew to treat more patients, perform more research, and teach more trainees than at any time in its distinguished history. He has taught locally, at McLean, Harvard Medical School, and the Massachusetts Institute of Technology, as well as lecturing nationally and worldwide to academic and lay audiences. He has directed continuously funded translational research projects and centers for 48 years.  Dr. Cohen has over 400 publications and 5 awarded patents.  He authored one popular book for lay audiences and has chapters in 19 textbooks. He has consulted to industry and clinical centers. He has been featured in national publications as one of the best doctors in America, been named Psychiatrist of the Year twice by the National Alliance on Mental Illness of Massachusetts, and has won awards for research, teaching, and clinical care. Our host, Gabe Howard, is an award-winning writer and speaker who lives with bipolar disorder. He is the author of the popular book, "Mental Illness is an Asshole and other Observations," available from Amazon; signed copies are also available directly from the author. Gabe is also the host of the "Inside Bipolar" podcast with Dr. Nicole Washington. Gabe makes his home in the suburbs of Columbus, Ohio. He lives with his supportive wife, Kendall, and a Miniature Schnauzer dog that he never wanted, but now can't imagine life without. To book Gabe for your next event or learn more about him, please visit gabehoward.com.

Dr. Ezekiel "Zeke" Emanuel is one of the world's most respected physician-philosophers. He's an oncologist, bioethicist, health policy expert, and professor at the University of Pennsylvania. His work sits at the intersection of medicine, ethics, public policy, and healthcare reform.Zeke has a MD from Harvard Medical School and a PhD in political philosophy from Harvard University. He also earned an MSc in biochemistry from University of Oxford and a BA in chemistry from Amherst College. It was great to sit down with one of the most respected researchers and academics in the world. I really enjoyed my time with the Doc, and while we agreed on nearly everything, we did diverge on one or two things but of course we did; we’re two humans. Enjoy!See omnystudio.com/listener for privacy information.

When disaster strikes, managing diabetes can become more challenging, from accessing medications and supplies to maintaining your usual routine. Having a plan in place can make all the difference. In this episode of Diabetes Day by Day, we're joined by Sylvia Kehlenbrink, MD, a leading expert in diabetes care during emergencies, to discuss how people living with diabetes and the people who love and support them can prepare for unexpected events.  Presented by: Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health, Abington, PA Sylvia Kehlenbrink, MD, Endocrinologist and Director of Global Endocrinology at Brigham and Women's Hospital, Part-time Instructor at Harvard Medical School, and Founder and Director of the Diabetes in Humanitarian Crises Program at the Harvard Humanitarian Initiative Do you have questions or comments you'd like to share with us? Leave a message at (703) 755-7288. Thank you for listening, and don't forget to "follow" Diabetes Day by Day! Additional resources: Diabetes Disaster Response Coalition's Disaster Preparedness Plan Find additional disaster preparedness resources and support at diabetesdisasterresponse.org and diabetes.org. Have questions? Contact the ADA's Center for Information.

BUFFALO, NY — July 23, 2026 — A new #research paper was #published in Volume 18 of Aging on July 8, 2026, titled “TM4SF1 is a surface marker of senescent pancreatic β-cells.” The study was led by first author Ana Beathriz Leite Lorente from Joslin Diabetes Center and Harvard Medical School, and São Paulo State University (UNESP), Brazil, and corresponding author Cristina Aguayo-Mazzucato from Joslin Diabetes Center and Harvard Medical School. Type 2 diabetes is characterized by insulin resistance and the progressive loss of pancreatic β-cell function. With aging and metabolic stress, senescent β-cells accumulate within the pancreas, producing less insulin while releasing inflammatory signals that contribute to disease progression. Although eliminating these dysfunctional cells has emerged as a promising therapeutic strategy, a major challenge has been identifying markers that distinguish senescent β-cells from healthy cells with sufficient precision. This study identifies transmembrane 4 L six family member 1 (TM4SF1) as a highly selective surface marker of senescent β-cells, providing a promising candidate for the future development of more selective therapies for type 2 diabetes. In this study, the researchers searched for cell-surface proteins that specifically identify senescent β-cells. Using RNA sequencing, flow cytometry, immunofluorescence, and analyses of both mouse and human pancreatic tissue, they compared TM4SF1 with the previously established senescence marker urokinase-type plasminogen activator receptor (uPAR/PLAUR). Their findings showed that TM4SF1 is expressed predominantly in senescent β-cells while exhibiting much lower expression in non-senescent β-cells and other tissues, making it a more β-cell-specific surface marker than uPAR. Full press release - https://www.aging-us.com/news-room/new-surface-marker-could-advance-precision-therapies-for-type-2-diabetes DOI - https://doi.org/10.18632/aging.206398 Corresponding author - Cristina Aguayo-Mazzucato - Cristina.aguayo-mazzucato@joslin.harvard.edu Abstract video - https://www.youtube.com/watch?v=tNbFKdleTJo Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206398 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, senescent β-cell, type 2 diabetes, transmembrane 4 l six family member 1, urokinase-type plasminogen activator receptor To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at: Bluesky - https://bsky.app/profile/aging-us.bsky.social ResearchGate - https://www.researchgate.net/journal/Aging-1945-4589 X - https://twitter.com/AgingJrnl Facebook - https://www.facebook.com/AgingUS/ Instagram - https://www.instagram.com/agingjrnl/ LinkedIn - https://www.linkedin.com/company/aging/ Reddit - https://www.reddit.com/user/AgingUS/ Pinterest - https://www.pinterest.com/AgingUS/ YouTube - https://www.youtube.com/@Aging-US Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Better sleep isn't just about getting more rest, it's about unlocking a healthier body, a clearer mind, and a deeper connection to your higher self. Eric Bigger and Stanford-trained sleep medicine physician Dr. Feby Maria Puravath Manikat explore how sleep can elevate your consciousness, boost your health, and help you show up as your highest self every day.About Dr. Feby Maria Puravath ManikatDr. Feby Maria Puravath Manikat is a Stanford-trained sleep medicine physician specializing in sleep health, longevity, and integrative medicine. She also trained at Cornell University in nutritional sciences and Harvard Medical School in Cognitive Behavioral Therapy for Insomnia (CBT-I). Blending science with holistic practices, she helps high-performing professionals optimize their sleep to improve health, energy, performance, and overall well-being. Dr. Feby also lectures Stanford's "Sleep and Dreams" course and serves as Sleep Director at Apple's AC Wellness, guiding Apple employees toward better rest, recovery, and peak performance.Website: https://www.febymariamd.com/aboutInstagram: https://www.instagram.com/febypuravath/Check out Miracle Season's collection: https://itsmiracleseason.co/collections/frontpageWork with me: https://www.ericbigger.com/workwithme?utm_source=podcast&utm_medium=podcast&utm_campaign=work_with_m...Connect with Simplified Impact: https://hubs.ly/Q02vvMJ90

Send us Fan MailWhat can American healthcare learn from global healthcare?  In our latest episode, Dr. Mark Stoltenberg, Harvard Medical School professor and Massachusetts General Hospital physician, joins Chris Comeaux to explore global healthcare, palliative care, hospice leadership, healthcare innovation, and the future of serious illness care in America.Healthcare leaders often assume innovation requires more money, more technology, or more specialists.  Dr. Stoltenberg argues the opposite, drawing from his work leading global palliative care programs throughout Latin America, the Caribbean, Africa, and other underserved regions.  He shares how resource-limited healthcare systems are pioneering solutions that can improve American healthcare, strengthen the healthcare workforce, and restore compassionate, person-centered care.Together, Chris and Dr. Stoltenberg discuss workforce shortages, Project ECHO, community-based care, volunteerism, family-centered decision-making, healthcare leadership, and why hospice and palliative care must preserve their founding values while continuing to innovate.Through moving patient stories—including a remarkable experience in Belize—they reveal why dignity, compassion, community, and purpose remain healthcare's greatest innovations.If you're a healthcare executive, hospice leader, physician, nonprofit executive, nurse, or business leader, this episode offers practical strategies for improving leadership, building stronger organizations, and delivering more compassionate care.In this episode you'll learn:✔ What America can learn from global healthcare systems✔ Why palliative care is rooted in social justice✔ How healthcare workforce shortages can be addressed creatively✔ Why Project ECHO is transforming healthcare education✔ How community-based care improves patient outcomes✔ Why family and spirituality remain essential to serious illness care✔ How great organizations preserve their mission while scaling innovationChapters00:00 Introduction00:23 Meet Dr. Mark Stoltenberg02:08 Leadership Superpower05:20 Palliative Care as Social Justice07:48 The Belize Story10:51  Innovation in Low-Resource Healthcare16:07  Project ECHO & Workforce Development20:58 Family, Community & Spiritual Care23:55 Loneliness & Rebuilding Community28:57 Preserving the Core While Scaling Access33:11  Part Two Preview

What can American healthcare learn from global healthcare?  In our latest episode, Dr. Mark Stoltenberg, Harvard Medical School professor and Massachusetts General Hospital physician, joins Chris Comeaux to explore global healthcare, palliative care, hospice leadership, healthcare innovation, and the future of serious illness care in America.Healthcare leaders often assume innovation requires more money, more technology, or more specialists.  Dr. Stoltenberg argues the opposite, drawing from his work leading global palliative care programs throughout Latin America, the Caribbean, Africa, and other underserved regions.  He shares how resource-limited healthcare systems are pioneering solutions that can improve American healthcare, strengthen the healthcare workforce, and restore compassionate, person-centered care.Together, Chris and Dr. Stoltenberg discuss workforce shortages, Project ECHO, community-based care, volunteerism, family-centered decision-making, healthcare leadership, and why hospice and palliative care must preserve their founding values while continuing to innovate.Through moving patient stories—including a remarkable experience in Belize—they reveal why dignity, compassion, community, and purpose remain healthcare's greatest innovations.If you're a healthcare executive, hospice leader, physician, nonprofit executive, nurse, or business leader, this episode offers practical strategies for improving leadership, building stronger organizations, and delivering more compassionate care.In this episode you'll learn:✔ What America can learn from global healthcare systems✔ Why palliative care is rooted in social justice✔ How healthcare workforce shortages can be addressed creatively✔ Why Project ECHO is transforming healthcare education✔ How community-based care improves patient outcomes✔ Why family and spirituality remain essential to serious illness care✔ How great organizations preserve their mission while scaling innovation

What if your relationship struggles aren’t just personal—but shaped by the systems you live in? Akilah Riley Richardson returns to explore how systemic trauma quietly shapes our relationships, nervous systems, and sense of self. Drawing from her work with marginalized couples, she introduces the concept of relational privilege and explains why healing cannot be separated from the social systems we live in. Together, Akilah and Sue challenge traditional Western therapy models, discuss the importance of “responsible externalizing,” and explore how therapists can create space for grief, imagination, and genuine connection instead of trying to fix what cannot simply be solved. “The experiences of marginalized people are often devalued even by helping professionals, and this text is my dedication to carving a space where we, as practitioners, can ensure that we are of service in a way that is rooted in the realities of our people. It is also a reflection of my obligation to marginalized couples and individuals. My sincere wish for them all is that they are never harmed in therapy but instead uplifted. ” – Akilah Riley-Richardson Time Stamps for The Hidden Weight of Systemic Trauma: How Oppression Shapes Our Relationships with Akilah Riley-Richardson (306) 02:05 The systemic trauma faced by marginalized couples 04:12 Barriers for global south therapists and voices 08:00 Fear, threat, and navigating space as a marginalized person 09:57 Relational privilege and systemic influence 12:03 The role of colonial Christianity in systemic trauma 17:50 The danger of model dogmatism in therapy 20:06 Neurobiological threat and systemic trauma 22:02 Practicing responsible externalizing in therapy 26:07 The grief of systemic trauma and loss 28:04 The limitations of evidence-based models 29:58 The need for imagination and community in healing 31:47 The concept of lostness and liminality in trauma 34:06 The danger of attachment to models and frameworks 35:59 Differentiating systemic from relational reality 38:10 Yoruba and indigenous healing traditions 41:59 The influence of colonialism and imperialism on therapy 43:53 Acknowledge systemic trauma in therapist self-awareness 49:57 Habits of survival and internalized oppression 51:52 The impact of systemic trauma on body and mind About our Guest – Akilah Riley-Richardson, MSW, CCTP Akilah Riley-Richardson, MSW, CCTP is a dedicated therapist, educator, and researcher with several years of experience. As a Certified Clinical Trauma Professional and STAIR Method Certified clinician, Akilah specializes in relational healing, focusing on the needs of couples and individuals, both in the Caribbean and internationally.Her expertise extends to supporting sexual and racial minorities, ensuring that her practice is inclusive and culturally sensitive. Akilah's commitment to education and advocacy has led her to consult for esteemed organizations, including NASTAD, I-TECH, CARPHA, and CVC, where she has made significant contributions to healthcare training and community support. She has presented her work at various prestigious forums, such as the Psychotherapy Networker Symposium, Academy of Therapy Wisdom, Harvard Medical School, Chicago School of Psychology and the Black Mental Health Symposium. From 2012 to 2025, she served as a Social Work Educator at the University of the Southern Caribbean, mentoring future leaders in the field. Currently, she serves as a Research Supervisor and Examiner at the University of the West Indies Global Campus. As the founder of the Relational Healing Institute and the creator of the P.R.I.D.E. model, Akilah is passionate about advancing relational therapies. Her book, “Marginalized Couples in Therapy” reflects this passion. Resources for The Hidden Weight of Systemic Trauma: How Oppression Shapes Our Relationships with Akilah Riley-Richardson (306) Marginalized Couples in Therapy: Interventions for Healing from Systemic Trauma – Akilah’s new book, use this link for 20% off. Get your copy today! Akilah’s website  – Resources, opportunities and additional information Beyond Attachment Styles course is available NOW!   Learn how your nervous system, your mind, and your relationships work together in a fascinating dance, shaping who you are and how you connect with others. Online, Self-Paced, Asynchronous Learning with Quarterly Live Q&A’s! Earn 6 Continuing Education Credits – Available at Checkout As a listener of this podcast, use code BAS15 for a limited-time discount.       You are invited!  Join our exclusive community to get early access and discounts to things we produce, plus an ad-free, private feed. In addition, receive exclusive episodes recorded just for you. Sign up for our premium Neuronerd plan!! Click here!!  Get your copy of Secure Relating here!!

Donate to the Institute: https://givenow.nova.edu/donations-for-me-cfs-research-2026  In today's episode, Haylie Pomroy sits down with Dr. Jaime Tartar, Professor and Chair of the Department of Psychology and Neuroscience at Nova Southeastern University, to reframe everything you think you know about stress and give you the science-backed tools to actually manage it. Dr. Tartar explains the biological difference between acute stress, chronic stress, and eustress, why worry is a physiological state that releases cortisol, and how perception is the single most powerful variable in whether stress helps or harms you. She walks through the neuroscience of cognitive reframing, the measurable brain benefits of gratitude, and the two-phase sleep cycle that determines how well you process emotions and recover from the day before.  She also covers screen time, electronic boundaries, the physiological impact of nature and movement on the stress response, and practical strategies for helping children navigate catastrophic thinking. For anyone navigating chronic illness, autoimmune conditions, long COVID, or ME/CFS, watch this episode of the Hope and Help For Fatigue and Chronic Illness podcast.     Jaime Tartar is a Professor of Neuroscience at Nova Southeastern University. She earned her Ph.D. in the Behavioral Neuroscience program at the University of Florida, where the focus of her research involved discovering long-term changes that occur in neurobiological pathways involved in stress responses and developing animal models of stress. Dr. Tartar has also completed Postdoctoral Training at Harvard Medical School, where she studied the neurological consequences of sleep perturbations using in vitro electrophysiological recording techniques. She also received training in Sleep Medicine at Harvard Medical School. She was also awarded an Honorary Doctorate at Nova Southeastern University. Dr. Tartar is the co-founder and CEO of The Society for Sports Neuroscience, an academic organization for the field of Sports Neuroscience. Dr. Tartar's current research is focused on stress, sleep, and athletic performance in humans.   LinkedIn: https://www.linkedin.com/in/jaime-tartar-1545889/    Haylie Pomroy, Founder and CEO of The Haylie Pomroy Group, is a leading health strategist specializing in metabolism, weight loss, and integrative wellness. With over 25 years of experience, she has worked with top medical institutions and high-profile clients, developing targeted programs and supplements rooted in the "Food is Medicine" philosophy. Inspired by her own autoimmune journey, she combines expertise in nutrition, biochemistry, and patient advocacy to help others reclaim their health. She is a New York Times bestselling author of The Fast Metabolism Diet.   Learn more about Haylie Pomroy's approach to wellness through her website: https://hayliepomroy.com   Instagram: https://www.instagram.com/hayliepomroy  Facebook: https://www.facebook.com/hayliepomroy  YouTube: https://www.youtube.com/@hayliepomroy/videos  LinkedIn: https://www.linkedin.com/in/hayliepomroy/  X: https://x.com/hayliepomroy    Thank you for tuning in to the Hope and Help For Fatigue and Chronic Illness Podcast. Sign up today for our newsletter.

Send us Fan MailRob Sambursky, MD, has more than 25 years of experience spanning the life sciences industry and clinical medicine. He is a fellowship-trained cornea specialist and currently serves as Chief Executive Officer of DefEYE, Inc.. Prior to joining DefEYE, Dr. Sambursky was one of the original founders of RPS Diagnostics and served as President and Chief Executive Officer of both RPS Diagnostics and Lumos Diagnostics. He led Lumos Diagnostics through its initialpublic offering on the Australian Securities Exchange. In addition, he was a founder and Executive Chairman of  Visus Therapeutics . Throughout his executive leadership roles, Dr. Sambursky also served as acting Chief Medical Officer for RPS Diagnostics, Lumos Diagnostics, and DefEYE.Dr. Sambursky currently serves as a strategic advisor to  Tenpoint Therapeutics  and is Board Chair of Advanced Ophthalmics, Inc. and Sustained Drug Delivery, Inc. He has extensive scientific and clinical expertise in ophthalmology, infectious disease, and medical sciences, and has served as an advisory board consultant to numerous ophthalmic therapeutic companies. Dr. Sambursky has authored dozens of patents and scientific publications, conceived a novel point-of-care diagnostic platform, and served as the clinical and regulatory lead supporting multiple international regulatory clearances and U.S. FDA 510(k) clearances with CLIA-waived designations. He has also played a key role in the successful commercialization of multiple diagnostic products in the United States and internationally.Dr. Sambursky is a practicing, board-certified ophthalmologist with fellowship training in corneal, external, and infectious disease. He earned a BA in Biology from Brown University, an MA in Medical Sciences with concentrations in biochemistry and microbiology from Boston University, and an MD from Boston University School of Medicine. He completed his medical internship at Mount Auburn Hospital, affiliated with Harvard Medical School, and completed both his ophthalmology residency and cornea fellowship at Wills Eye Hospital, where he also served as Co-Chief Resident.

Original air date: July 25, 2024Dr. Joyce Maguire Pavao, Ed.D., LCSW, LMFT, was the Founder and CEO of Center for Family Connections, Inc. (CFFC, 1995-2012) in Cambridge and New York, Founder and Director of Riverside After Adoption Consulting and Training (AACT, 2012 to 2015), PACT (Pre/Post Adoption Consulting and Training, 1982-present), and Pavao Consulting and Coaching. Dr. Pavao has done extensive training, both nationally and internationally. She is a lecturer in Psychiatry at Harvard Medical School, and she has consulted to various public and private child welfare agencies, adoption agencies, schools, and community groups, as well as probate and family court judges, lawyers, and clergy. Additionally, she has worked closely with individuals and families touched by adoption, foster care, and other complex blended family constructions.Recommended Resources: "Twice Born" by Betty Jean Lifton "The Adoption Triangle" byArthur D. Sorosky, M.D. Annette Baron, M.S.W. Reuben Pannor, M.S.W. "Lethal Secrets" by Annette Baran and Reuben Pannor "The Family of Adoption" by Dr. Joyce Maguire Pavao

Every day we encounter the stimuli of our lives. Events and people. And we have feelings about most all of it. Some good, some bad, some fairly neutral, but we are processing everything through how we make meaning of things. Some of us have negative emotions about certain things that don't serve us. After 15 years as an elite cyclist I came to equate negative emotions to rain, as I associated rain with riding in it or riding indoors to stay out of it. I held this negative emotions for many years after I retired, for no real reason. From a habit of speeding and rolling stop signs I grew in myself, negative emotions toward cops who frequently pulled me over. Now, even when I'm obeying the traffic laws, I experience a negative emotion when I see a cop. These negative emotions, I created. And now I've retained even after the circumstances have changed. Analogies to question the emotions we hold from past experiences that may not be serving us today. My guest in this episode Dr. Julia DiGangi. Julia is a neuropsychologist who completed her residency at Harvard Medical School, Boston University School of Medicine, and the US Department of Veterans Affairs, and is the author of a book called Energy Rising: The Neuroscience of Leading with Emotional Power. Dr DiGangi has nearly two decades of experience studying the connection between our brains and our behavior and has worked with leaders around the world including the White House Press Office and the US Special Forces. She shows people, at work and at home, how to harness the power of the brain to lead more satisfying and emotionally intelligent lives. You can find her on Instagram with a following of 250k @drjuliadigangi Sign up for your $1/month trial period at shopify.com/kevin Go to shipstation.com and use code KEVIN to start your free trial. Learn more about your ad choices. Visit megaphone.fm/adchoices

Hip fractures are a leading cause of disability and death in older adults. This episode summarizes  risk factors, prevention, and medical and surgical management of  hip fractures. JAMA Deputy Editor Mary M. McDermott, MD, interviews Douglas Kiel, MD, MPH, of Harvard Medical School and Marcus Institute for Aging Research. Related Content: Hip Fractures

At the International Anesthesia Research Society (IARS) and Society of Critical Care Anesthesiologists (SOCCA) meeting in Montreal, TopMedTalk hosts Mike Grocott and Desiree Chappell speak with Dr Faye Evans, Senior Associate in Perioperative Anesthesia at Boston Children's Hospital and Associate Professor of Anaesthesia at Harvard Medical School and Director of Partnerships on the Board of Directors for the World Federation of Societies of Anaesthesiologists (WFSA). The conversation covers efforts to improve access to safe surgery and anesthesia for children globally. Evans explains the WFSA as a society of over 150 member societies focused on advocacy, safety, quality, publications, short courses (including SAFE), and a fellowship program that has trained over 400 fellows from 62 countries. She highlights growing emphasis on leadership, teaching, and evaluation within fellowships and describes Pediatric Anesthesia Training in Africa (PATA), formed to expand fellowship training, which has developed a shared curriculum and launched four programs with support from ELMA Philanthropies and Smile Train. Evans outlines ways to get involved through teaching, virtual support, and donations via the WFSA website. If you would like to support the WFSA Scholars Program we mention this link in the show: https://wfsahq.org/get-involved/donate/ -- The 2026 International Practicum on Cardiopulmonary Exercise Testing will be held at the Balmer Lawn Hotel in Brockenhurst, UK, from September 16th to 18th this year. It is organised by iPOETTS , the international perioperative testing and training society. Come and join us at this premier educational event designed for clinicians, scientists, and healthcare professionals interested in sport, exercise, and perioperative medicine. This is an International Perioperative Testing and Training Society accredited event so when you attend you can get your iPOETTS accreditation, showing that you are a practitioner who has reached a high, standardized level of competence in performing and interpreting Cardiopulmonary Exercise Testing (CPET) for patients preparing for major surgery. Go now to http://www.ebpom.org

In this episode, Dr. Stuart Slavin is joined by Dr. Daniel Saddawi‑Konefka, associate professor of anesthesia, and Dr. Matthew Tung, instructor in anesthesia, both at Harvard Medical School. They discuss their JAMA viewpoint, Meaning and Comfort in Physician Well‑Being: An Integrated Framework, and explore how two complementary dimensions of well‑being—meaning and comfort—can help physicians thrive throughout their careers. Drawing on concepts rooted in ancient Greek philosophy, Drs. Saddawi‑Konefka and Tung examine the relationship between eudaimonia (the sense of purpose and fulfillment that comes from service, growth, and connection) and hedonia (the well‑being associated with comfort, safety, and the reduction of unnecessary burdens). They discuss why these concepts are often framed as competing priorities in medicine and argue instead that both are essential components of sustainable physician well‑being. The conversation also explores practical applications within graduate medical education, including fostering intrinsic motivation, promoting autonomy, competence, and relatedness, and creating opportunities for learners to connect with the meaning inherent in patient care. Throughout the discussion, the speakers highlight how organizational efforts to reduce administrative burdens and improve working conditions can create the space needed for physicians to engage more deeply with purpose, connection, and professional fulfillment. Listeners will gain valuable insights into how an integrated approach to meaning and comfort can support well‑being for learners, educators, and practicing physicians alike. Podcast Chapters (00:00) – Intro and Guest Introduction (01:15) – Origins of the Meaning and Comfort Framework (03:00) – Rethinking Physician Well-Being (04:30) – Understanding Meaning and Comfort (06:03) – Hedonia, Eudaimonia, and Well-Being (08:10) – Finding Life and Meaning in Work (10:06) – Balancing Purpose and Comfort (11:20) – Intrinsic Motivation and Medical Training (12:56) – Self-Determination Theory in Practice (14:47) – Autonomy, Competence, and Relatedness (16:39) – Creating Cultures of Meaning and Connection (18:18) – Gratitude, Recognition, and Daily Purpose (19:45) – Rediscovering Meaning in Everyday Clinical Work (21:20) – When Loss of Meaning Signals a Need for Support (22:27) – Hedonic Adaptation and Sustainable Well-Being (23:11) – Integrating Meaning and Comfort (24:48) – Closing and Resources

For years, body image concerns and eating disorders were viewed as problems that primarily affected girls and women. But boys and men also struggle with body dissatisfaction, eating disorders, and body dysmorphia -- often in ways that go unnoticed. Roberto Olivardia, PhD, a clinical psychologist at McLean Hospital and Harvard Medical School, discusses muscle dysmorphia; why body image disorders in men are frequently overlooked; how social media, the "manosphere," and trends like looksmaxxing are shaping young men's ideas about appearance and masculinity; and what parents, clinicians, and others can do to help boys and men build a healthier relationship with their bodies. Learn more about your ad choices. Visit megaphone.fm/adchoices

What if the greatest shift in how you lead, work, and live isn't about learning another skill, but about changing the way your brain experiences the world?Amy sits down with Dr. Dawson Church, award-winning science writer, researcher, and author of Spiritual Intelligence, to explore the growing body of neuroscience revealing that emotional regulation, attention, compassion, and presence are not fixed personality traits. They are trainable capacities that reshape the brain over time.For years, spirituality has often been dismissed as something personal, abstract, or impossible to measure. Dawson challenges that assumption by sharing the research behind the four neural circuits that support spiritual intelligence and why strengthening them can transform everything from workplace performance to relationships and overall wellbeing. Together, Amy and Dawson also unpack why traditional meditation doesn't work for everyone, how evidence-based practices like EFT tapping and Eco Meditation accelerate change, and why cultivating inner awareness may be one of the most practical leadership skills available today.If you've ever wondered whether there's a science behind feeling calmer under pressure, responding with greater compassion, or unlocking more creativity without pushing harder, this conversation offers a compelling new perspective on what becomes possible when we intentionally train the brain that shapes every experience of our lives.Download your free copy of Dr. Dawson Church's The EFT Mini-Manual and bonus EcoMeditation at https://dawsongift.com/Moments That Create Momentum:The Brain You Practice Becomes the Life You Experience: Discover why spiritual intelligence isn't a personality trait you're born with, but a set of neural pathways you can intentionally strengthen.The Four Circuits Behind Calm Under Pressure: Explore how emotional regulation, attention, compassion, and self-awareness shape the way you lead, respond, and connect long before a stressful moment arrives.Why Meditation Doesn't Work for Everyone: Learn why quieting your mind isn't the goal, and how science-backed practices can make inner transformation more accessible.Performance Begins Long Before Productivity: Understand why your greatest breakthroughs may come from changing your internal state instead of pushing yourself to work harder.Training the Brain for Something Bigger Than Success: See how developing spiritual intelligence can shift not only how you perform at work, but how you experience your relationships, purpose, and everyday life.About the Guest:Dr. Dawson Church is an award-winning science writer, researcher, and bestselling author whose work explores the intersection of neuroscience, psychology, and human potential. Through more than 100 published clinical studies and collaborations with researchers from institutions including Harvard Medical School, Duke, Emory, and Columbia, his research has examined how meditation, emotional regulation, and self-transcendent experiences can reshape the brain and improve wellbeing. He is the author of The Genie in Your Genes, Mind to Matter, Bliss Brain, and Spiritual Intelligence.Beyond his research and writing, Dawson is the founder of the National Institute for Integrative Healthcare and the Veterans Stress Solution, a nonprofit initiative that has provided free PTSD treatment to more than 22,000 veterans and their family members. He also developed EcoMeditation, an evidence-based practice designed to make meditation accessible to beginners, and continues to share research-backed approaches that help people reduce stress, cultivate resilience, and unlock their full potential.https://dawsonchurch.com/https://www.facebook.com/dawsonchurchhttps://www.youtube.com/@EftuniverseEFThttps://twitter.com/EFTUniversehttps://www.linkedin.com/in/dawson-church-68b4a8/https://www.instagram.com/theeftuniverse/About Amy:Amy Lynn Durham, known by her clients as the Corporate Mystic, is the founder of the Executive Coaching Firm, Create Magic At Work®, where they help leaders build workplaces rooted in creativity, collaboration, and fulfillment. A former corporate executive turned Executive Coach, Amy blends practical leadership strategies with spiritual intelligence to unlock human potential at work.She's a certified Executive Coach through UC Berkeley & the International Coaching Federation (ICF) In addition, Amy holds coaching certifications in Spiritual Intelligence (SQ21), the Edgewalker Profile, and the Archetypes of Change . In addition to being the host of the Create Magic At Work® podcast, Amy is the author of Create Magic At Work®, Creating Career Magic: A Daily Prompt Journal and the founder of Magic Thread Media™. Through her work, she inspires intentional leadership for thriving workplaces and lives where “magic” becomes reality.Connect with Amy:https://createmagicatwork.net/https://www.linkedin.com/company/create-magic-at-workhttps://www.facebook.com/112951637095427https://www.instagram.com/createmagicatworkhttps://www.youtube.com/channel/UCnEm4h3fUgaq8qgvZpz6dGgThanks for listening!Thanks so much for listening to our podcast! If you enjoyed this episode and think that others could benefit from listening, please share it using the social media buttons on this page.Do you have some feedback or questions about this episode? Leave a comment in the section below!Subscribe to the podcastIf you would like to get automatic updates of new podcast episodes, you can follow the podcast on Apple Podcasts or your favorite podcast app.Leave us an Apple Podcasts reviewRatings and reviews from our listeners are extremely valuable to us and greatly appreciated. They help our podcast rank higher on Apple Podcasts, which exposes our show to more awesome listeners like you. If you are enjoying the show, please leave us a review on Apple Podcasts.Mentioned in this episode:This show was brought to you in part by the Magic Thread Media Network. To learn more visit: https://magicthreadmedia.com/

My guest this week built a headset that turns your own brainwaves into a video game, and the point of that game is to teach your brain to drop into a flow state on demand, even under pressure.Steve Gullans spent 18 years as a scientist at Harvard Medical School, ran a venture fund, took a company public and rang the NASDAQ bell, then came out of retirement to bring this technology to market. His company, Thynk, is starting in public schools, where he says kids playing about an hour a week show calmer behavior and measurable gains, and it is moving next into elite sports. We get into why a big gaming company has not built this, what the data reveals about how distracted we have all become, what "neurodivergent" actually means, his take on peptides and GLP-1s, and the one piece of advice he gives every founder about the CEO's real job.Steve Gullans is the CEO of Thynk. He was previously a professor at Harvard Medical School, co-founded a venture fund with Juan Enriquez, and has been close to around 60 companies as a founder, investor, and operator.This conversation is for information and general interest. It is not medical advice.Subscribe for new episodes: Youtube link: [ https://www.youtube.com/@palebluenexus ] The Last 20, my newsletter: [NEWSLETTER LINK] The Aloomii Playbook eCourse: [aloomii.gumroad.com]

In this episode, hosts Lee-Sean Huang and Giulia Donatello sit down with Jeff Leitner, the co-founder of UX for Good, architect of Norm Design, and a partner to organizations ranging from the US State Department and NASA to Harvard Medical School. Together, they unpack the core ideas behind his Summer 2026 Stanford Social Innovation Review article, "The Science of Norm Design," exploring why smart, well-funded initiatives fail roughly 70% of the time. Jeff shares his extensive experience studying the "invisible architecture" of social environments. He offers a critical challenge to the design industry, inviting practitioners to look past boilerplate briefs and standard user research to systematically uncover and design for the unwritten rules that dictate human behavior.In This EpisodeHere is the section trimmed down by 25% for a faster, punchier read, with all text formatted in plain text:The definition of norm design. Jeff defines norm design as an essential layer built on top of traditional research to uncover a group's informal, unwritten rules. Because every solution lands within a complex social ecosystem, these hidden dynamics ultimately dictate whether a design succeeds or fails. The 70% organizational failure rate. Stagnant for decades, the standard failure rate for organizational change is famously high. The uncomfortable reality is that most interventions fail because they inadvertently obey the exact same unwritten rules as the problems they are trying to fix. The New Orleans musicians' paradox. Partnering with UX for Good to help local musicians, who average $24,000 a year, the team found that standard financial literacy training routinely failed. A norm-based approach revealed that musicians viewed asking for tips as humiliating. By bypassing the ask and adding a tipping line directly to club receipts, they successfully transferred thousands of dollars to bands. Unwritten rules vs. employee manuals. Social norms are rarely documented. To find a company's true constraints, Jeff suggests asking employees what they would tell a best friend over drinks about "how the place really works," rather than what's printed in the onboarding manual. The structural empathy trap. While designers champion empathy, leaning too deeply into a user's perspective can cause researchers to absorb the same invisible constraints that the target group can't see, effectively blinding the designer to the overarching social norms. Empathy vs. compassion in Rwanda. At the Kigali Genocide Memorial, the team challenged the default industry strategy of showing horror to inspire action. Brain research shows that witnessing suffering floods our pain circuits, causing distress, fatigue, and shutdown. By profiling ordinary heroes, they engaged the brain's compassion networks to cultivate the will to act. How success derailed NASA. Jeff discovered that 100% of interviewed NASA staff anchored their operational norm to JFK's 1962 "Moonshot" speech. However, waiting for a singular political figure to rally the public blinded the agency to the modern reality of private spaceflight, turning a historic triumph into a systemic roadblock. ResourcesThe Science of Norm Design by Jeff Leitner (Stanford Social Innovation Review) – https://ssir.org/articles/entry/the-science-of-norm-designLeitner Studio Official Website – leitnerstudio.com UX for Good Nonprofit – uxforgood.org Cracking the Code of Change by Nitin Nohria and Michael Beer, the original source of the 70% failure rate of change initiatives (Harvard Business Review)  – https://hbr.org/2000/05/cracking-the-code-of-changeAIGA Design Podcast Feedback and Voicememos – podcast@aiga.org 

Most of what people know about Dissociative Identity Disorder (DID) comes from movies and short videos, and those media portrayals often have little to do with what DID is actually like. To get the real picture, today Forrest is joined by Dr. Milissa Kaufman and Dr. Lauren Lebois, experts in dissociative disorders and trauma research. Dr. Kaufman had DID herself, went through treatment, and made a full recovery.  They explore the spectrum of dissociation, from everyday experiences to clinical presentations like DID, before talking about how DID develops as a childhood adaptation to trauma, the problem with the term “multiple personality disorder,” and what the brain science tells us. Milissa describes her own “inside people,” the shame and secrecy associated with DID, and the slow shift from "that wasn't me" to "that was me all along." They then cover what treatment looks like, what to actually look for in a therapist, and what recovery means. About our Guests: Dr. Milissa Kaufman is a trauma psychiatrist at McLean Hospital and Associate Professor of Psychiatry at Harvard Medical School. Dr. Lauren Labois is a cognitive neuroscientist and Assistant Professor of Psychiatry at Harvard Medical School. They are co-directors of the Dissociative Disorders and Trauma Research program at McLean Hospital. Check out the Trauma Continuum at Hill Center: https://traumacontinuum.org/ Key Topics: 0:00: Intro and Dr. Kaufman's personal experience with DID 6:51: The spectrum of dissociation: Depersonalization, Derealization, and Dissociative Identity Disorder 17:12: Dr. Kaufman's experience of DID 22:58: The paradoxes and shame involved with DID 36:46: History of skepticism around DID, and the role of modern neuroscience 43:09: Treatment for DID and trauma-informed treatment 1:00:43: What healing and recovery looks like 1:10:48: Recap Support the Podcast: We're on Patreon! If you'd like to support the podcast, follow this link. Take our audience survey: https://rickhanson.com/survey/ Sponsors Go to Zocdoc.com/BEINGWELL to find and instantly book a top-rated doctor today. Learn more about your ad choices. Visit megaphone.fm/adchoices

The biopsychosocial model of health has been around since the late 1970s. In musculoskeletal rehabilitation, the biopsychosocial model is prominent in clinical practice guidelines for a variety of different conditions, with different approaches advocated for how to provide rehabilitation within the model.Today, Dr Kate Jochimsen guides JOSPT Insights listeners through psychologically-informed rehabilitation practice - taking principles that have become quite prominent in the chronic low back pain field and seeing how they might apply to young, active people with chronic hip pain.Dr Jochimsen is an Assistant Professor in the Department of Psychiatry at Harvard Medical School, a researcher at the Center for Health Outcomes and Interdisciplinary Research at Massachusetts General Hospital (MGH), and a member of the Physical Therapy Residency Faculty at the MGH Institute for Health Professions. Her work bridges the gap between sports medicine and psychology, with a primary focus on chronic pain and hip injuries.------------------------------RESOURCESOSPRO yellow flags tool: https://www.jospt.org/doi/10.2519/jospt.2016.6487Screening for yellow flags - clinical framework: https://www.jospt.org/doi/10.2519/jospt.2021.10570Pain Catastrophizing Scale: https://www.sralab.org/rehabilitation-measures/pain-catastrophizing-scaleAssociation between pain and function in people with hip pain - systematic review: https://pubmed.ncbi.nlm.nih.gov/41020468/JOSPT's July 2026 hip-focused issue (10 hip articles): https://www.jospt.org/toc/jospt/56/7Association for Applied Sport Psychology mental wellness resource center: https://appliedsportpsych.org/resources/mental-wellness-resource-center/Why things hurt - TEDx with Professor Lorimer Moseley: https://www.youtube.com/watch?v=gwd-wLdIHjsPsychologically informed practice in low back pain (case report): https://www.jospt.org/doi/10.2519/josptcases.2025.0177Psychologically informed physical therapy for musculoskeletal conditions (APTA paid course): https://www.orthopt.org/course/33-3-psychologically-informed-physical-therapy-for-musculoskeletal-disordersManaging persistent pain (APTA paid course): https://learningcenter.apta.org/products/persistent-pain-management-certificate-a-comprehensive-learning-series

How do you calm your nervous system when survival mode has quietly become your baseline? Dr. Eva Selhub joins Mike Vera on the Healthy & Awake Podcast to get into stress, anxiety, and burnout, and instead of a standard Q&A, Mike brought four case studies, the archetypes he sees over and over in sessions as a health coach: the guy stuck in the cookie-and-coffee loop who asks why even bother, the person waking at 2 a.m. with layoffs circling, the mom quietly dreading the empty nest, and the caregiver running on empty. Resilience is more than toughness, she says, and she argues that the coping most people reach for only brings the stress response part of the way down, which leaves the baseline creeping higher over time.

At Lifespan, our mission is to help you and your loved ones live your longest, healthiest lives - while supporting medical research into breakthroughs to improve all lives. We're building the world's largest longevity community: Join us at https://lifespan.com. Follow us on YouTube, Apple, and Spotify for new Lifespan episodes every 2 weeks.                               __________________________________________ In this second installment of Lifespan's two-part series on calorie restriction and fasting, Dr. David Sinclair, A.O., Ph.D.  – Professor of Genetics at Harvard Medical School and a pioneer in longevity research – explores how to fast effectively for health and longevity. Drawing on decades of research and the latest scientific evidence, Dr. Sinclair explains how to approach fasting effectively, what happens inside your body at the 12-, 24-, and 48+-hour marks, how to overcome common plateaus, and the key considerations for women, men, and people at different stages of life.  Whether you're new to fasting or looking to refine your approach, this episode provides a practical, evidence-based guide to using fasting to support metabolism, cellular repair, and healthy longevity.                                __________________________________________ Partners of the Lifespan show help us keep this program freely available as an educational resource while also supporting medical research. We only collaborate with partners whose products are grounded in science and that our team has personally used for years. Our selected partners make it convenient for the Lifespan audience to access the tools and technologies featured in this episode - from exogenous fuel for neurons (Ketone-IQ), to wearables that track recovery, strain, and sleep (WHOOP), to smart devices that measure key health metrics such as visceral fat and muscle mass (Withings). If you'd like to learn more or try these tools: ○ Ketone-IQ: Get 30% off your first monthly order at https://ketone.com/lifespan or with code LIFESPAN ○ WHOOP: Get a free WHOOP band and one month of membership at https://join.whoop.com/LIFESPAN or with code LIFESPAN ○ Withings: Get 10% off smart health devices at https://withings.com/lifespan or with code LIFESPAN                                __________________________________________ Legal & Medical Disclaimers The Lifespan show and all related content are provided for informational and educational purposes only and are not intended as medical advice, diagnosis, or treatment. Nothing presented should be interpreted as a recommendation to diagnose, treat, cure, or prevent any disease or medical condition. This content is not a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. You should always consult with a licensed physician or other qualified healthcare professional before making decisions about your health, including starting, stopping, or modifying any treatment, supplement, diet, or exercise program. The information shared reflects the views and opinions of the host and guests and is based on the scientific literature, their experience and expertise, and general wellness principles. Listening to or engaging with Lifespan content does not establish a doctor–patient or clinical relationship.  Health and longevity outcomes can vary significantly between individuals. Any references to studies, interventions, products, or protocols are not guarantees of specific results, and individual responses may differ. From time to time, Lifespan may discuss or partner with third-party products or services. These references are provided for informational purposes only and should not be considered medical recommendations or endorsements of efficacy for any individual. Lifespan Foundation is an independent 501(c)(3) non-profit organization whose mission is to support medical research.   The views expressed by Dr. David Sinclair, A.O., Ph.D., are his own and do not represent those of Harvard University, Harvard Medical School, or any affiliated institutions.

Welcome back to a special encore presentation of Turn on the Lights! As we continue our transition series, our new host, Dr. Philip, has hand-selected one of our most-listened-to and impactful conversations from the archives to highlight once again. Dr. Philip brings back to attention this conversation with Dr. Ben Sommers on how Medicaid work requirements and reduced ACA subsidies are driving coverage losses through administrative barriers, with far-reaching consequences for patient health and the stability of safety-net hospitals and communities. Summary: Millions of Americans could lose health coverage in the coming years, and the consequences may be more profound than most people realize. In this episode, Dr. Ben Sommers, the Huntley Quelch Professor of Health Care Economics at the Harvard T.H. Chan School of Public Health, and professor of medicine at Harvard Medical School and Brigham & Women's Hospital, talks about how new federal policies, including Medicaid work requirements and the rollback of Affordable Care Act subsidies, are reshaping access to health insurance in the U.S. Drawing on extensive research, he explains why these changes are expected to increase uninsured rates without meaningfully boosting employment. Dr. Sommers also shares evidence from prior state experiments showing that administrative red tape, not a lack of willingness to work, drives coverage loss. He outlines the ripple effects on patient health, safety-net providers, and hospitals, especially in rural and underserved communities. Tune in to understand what these policy shifts mean for patients, providers, and the future of the U.S. health care system. Things You'll Learn: New federal policies could result in more than 15 million Americans losing health insurance over the next decade. Medicaid work requirements do not meaningfully increase employment but do lead to significant coverage losses due to administrative barriers. Evidence from Arkansas shows that most people who lost Medicaid coverage were eligible and already working or exempt, but were tripped up by reporting requirements. Losing health insurance is associated with worse health outcomes, delayed care, increased financial strain, and higher rates of preventable death. Expanding health coverage increases overall system spending, but it delivers substantial benefits in terms of health, stability, and longevity for individuals and families. Reduced Medicaid funding and rising uninsured rates will place a severe strain on safety-net hospitals and providers, especially in rural and underserved areas. Changes to ACA marketplace subsidies and Medicaid rules will affect patients, providers, and communities in phases, with political and health system consequences unfolding over several years. Resources: Follow the Harvard T.H. Chan School of Public Health on LinkedIn and explore their website! Learn more about the One, Big, Beautiful Bill here! Learn more about your ad choices. Visit megaphone.fm/adchoices

Gut feelings, trusting your gut, butterflies: We have lots of expressions about how our brains and our bowels are intertwined. But how well do we understand the science of this on the biomolecular level? And which of those organs is actually in the driver's seat?  Flora churned through the details with gastroneurologists Emeran Mayer and Trischa Pasricha on stage at the 2026 Aspen Ideas Festival in Colorado.  Guests: Dr. Emeran Mayer is distinguished research professor at the David Geffen School of Medicine at UCLA, and executive director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience. Dr. Trisha Pasricha is a neurogastroenterologist and physician-scientist at Beth Israel Deaconess Medical Center as well as an assistant professor of medicine at Harvard Medical School. Other episodes you may enjoy: How to poop better, according to a gastroenterologist The Gurgling, Growling History Of The Gut A transcript for this episode is available at sciencefriday.com. Subscribe to this podcast. Follow our show on Instagram, TikTok, Facebook, and Bluesky @scifri and sign up for our newsletters. Got a science question that's keeping you up at night? Call us: 877-472-4374 Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Khameer Kidia is a physician and an anthropologist, works at Harvard Medical School and the University of Zimbabwe, and spends his life between Washington DC and Harare. Kidia has many accolades to his name – he is a Rhodes scholar and a 2023 New America Fellow. His papers have appeared in elite medical journals and his stories in the New York Times. His recent book, which we will discuss, was covered by The Washington Post. His experience navigating two cultures and his expertise across disciplines is what allows him to see that psychiatry, as it currently stands, needs to end. In this interview, we discuss how the tentacles of an exploitative global order reach into people to wreak havoc with their lives and in their minds. Disclosing his own difficult history with stimulant medications, he exposes how current psychiatric practices superficially anesthetize pain in order to return us back on the hamster wheel of productivity. Sharing his mother's struggles with 'nervous breakdowns', Kidia shows us the importance of patient autonomy and liberty, and the grace in letting go when people choose a path that doesn't align with our priorities. *** Thank you for being with us to listen to the podcast and read our articles this year. MIA is funded entirely by reader donations. If you value MIA, please help us continue to survive and grow. https://www.madinamerica.com/donate/ To find the Mad in America podcast on your preferred podcast player, click here: https://pod.link/1212789850 © Mad in America 2026. Produced by James Moore https://www.jmaudio.org

In today's Mayo Clinic Ophthalmology Podcast, Dr. Sophie Bakri and I visit with retina specialist Dr. Joan Miller of Harvard Medical School. Her pioneering work helped establish photodynamic therapy for age-related macular degeneration and contributed to the development of anti-VEGF therapies that have transformed the lives of millions of patients worldwide. Tune in to hear about her leadership journey and remarkable career advancing treatments for AMD. Subscribe to the podcast:  https://MayoClinicOphthalmology.podbean.com  Follow and reach out to us on X and IG: @mayocliniceye  

Recently I was talking to my friend Dr. Chris Willard, and he mentioned a desire to have a conversation about the effects of patriarchy on men, and especially younger men, from both a psychological and spiritual perspective. Like myself, Chris is a progressive Buddhist dad, and like me, he cares about helping people develop a more emotionally attuned approach to life. Chris has a particular clinical focus on working with younger people, including younger boys and men. What followed was a wide-ranging (and only slightly rambling, but hey, it's a podcast!) conversation that explored the current (troubled) state of masculinity from a spiritual, psychological, scientific, cultural and political perspective. Dr. Christopher Willard, (Psy. D.) is a clinical psychologist, author and consultant based in Massachusetts. He has spoken in forty countries, and has presented at two TEDx events. He is the author of twenty books, including Alphabreaths, Growing Up Mindful, Feelings are Like Farts, and The Neuroscience of Negotiation. His thoughts on mental health have been featured in The New York Times, The Washington Post, mindful.org, cnn.com, and elsewhere. He teaches at Harvard Medical School. Subscribe now (Episode available wherever you get your "pods," Apple, Ethan's Website, Substack and every other pod place). Last year, with your subscriptions, we were able to release more episodes than any previous year. This was only possible with your support. Please consider becoming a free or paid subscriber here. Show Notes and More cool resources: Check out our sponsor platform, A Mindful World! A new free video course from Ethan on Metta (lovingkindness) meditation is now available at this link. Sign up for our Fall retreat at the Garrison Institute at this link. Sign up for the August visualization meditation workshop here. Paid subscribers to The Road Home will receive occasional extras like guided meditations, extra podcast episodes and more! The Thursday Meditation Group happens each week at 8am ET on Thursdays, and guided audio meditations are released monthly. Another bonus podcast for paid subscribers discussed the obstacle of resistance to meditation practice, and Ethan also offered instruction in Metta meditation toward yourself. These are all available to paid subscribers. You can also subscribe to The Road Home podcast wherever you get your pods (Apple, Ethan's Website, etc). Subscribe now You can now order personally signed copies of Ethan's books at his website. You can also subscribe to The Road Home podcast wherever you get your pods (Apple, Ethan's Website, etc).

Michael Chernew, PhD, professor of healthcare policy at Harvard Medical School, joins Josh Israel, MD, and Sean Cavanaugh to discuss the Medicare Payment Advisory Commission (MedPAC) and its role in the Medicare program, including Medicare Advantage (MA) and the Medicare Shared Savings Program (MSSP). Dr. Chernew, who served as MedPAC chair from 2020-2026, shares how MedPAC provides evidence-based recommendations to Congress on payment policies, access and quality of care in Medicare. They examine Medicare solvency, cost-effectiveness concerns in both MA and MSSP, as well as larger challenges to improving the healthcare system for patients and physicians.

Hey Heal Squad! We are back with Dr. Fatima Cody Stanford from Harvard Medical School & Massachusetts General Hospital, and we are picking up right where we left off about GLP-1s. Dr. Fatima gets into the stuff people are most confused about. She explains why your body is literally wired to fight back every time you try to lose weight, and why that is not a personal failure. It is just biology. She also gets real about side effects (no sugarcoating here!)  and breaks down the very real risk of muscle loss on these medications, plus she shares the exact cardio-to-strength ratio she recommends for every decade of life. Yes, by decade.Then Maria finally asks the question the whole episode has been building toward...who is a GLP-1 actually for? Dr. Fatima answers it directly and also breaks down the difference between single, dual, and triple agonists — including a clinical trial showing nearly 30% total body weight loss that could change everything we know about treating obesity. And Patreon members, we have a bonus episode waiting for you! Dr. Fatima gets into something we did not cover in the main episodes: why you should think twice before ordering GLP-1s through Instagram. It's worth a listen!  HEALERS & HEAL LINERS Your Body Isn't Broken,  It's Doing Exactly What It Was Designed to Do: Dr. Fatima explains why the body defends its weight set point with everything it has. It isn't a failure of willpower. It is biology. Understanding this changes how you think about these medications. The Muscle Loss Nobody's Warning You About: GLP-1 medications can cause you to lose lean muscle — not just fat. Dr. Fatima breaks down the specific strength-to-cardio ratio she recommends for every decade of life. This is the practical guidance that should come with every prescription but rarely does. Obesity Is a Disease: Dr. Fatima  shares what it is like to be ridiculed and stigmatized for caring for patients with obesity and makes the case that the language we use around weight has real consequences for real people. It is a reminder that compassion and science are not mutually exclusive. They are both required. HEAL SQUAD SOCIALS IG: https://www.instagram.com/healsquad/ TikTok: https://www.tiktok.com/@healsquadxmaria HEAL SQUAD RESOURCES: Heal Squad Website:https://www.healsquad.com/ Heal Squad x Patreon: https://www.patreon.com/HealSquad/membership Maria Menounos Website: https://www.mariamenounos.com My Curated Macy's Page: https://stylecrew.macys.com/@mariamenounos EMR-Tek Red Light: https://emr-tek.com/discount/Maria30 for 30% off Airbnb: https://www.airbnb.com/host GUEST RESOURCES: Follow Dr. Fatima on Instagram: https://www.instagram.com/askdrfatima/?hl=en More info on Dr Fatima here: https://askdrfatima.com/ ABOUT MARIA MENOUNOS: Emmy Award-winning journalist, TV personality, actress, 2x NYT best-selling author, former pro-wrestler and brain tumor survivor, Maria Menounos' passion is to see others heal and to get better in all areas of life. ABOUT HEAL SQUAD x MARIA MENOUNOS: A daily digital talk-show that brings you the world's leading healers, experts, and celebrities to share groundbreaking secrets and tips to getting better in all areas of life. DISCLAIMER: This Podcast and all related content (published or distributed by or on behalf of Maria Menounos or http://Mariamenounos.com and http://healsquad.com) is for informational purposes only and may include information that is general in nature and that is not specific to you. Any information or opinions provided by guest experts or hosts featured within website or on Company's Podcast are their own; not those of Maria Menounos or the Company. Accordingly, Maria Menounos and the Company cannot be responsible for any results or consequences or actions you may take based on such information or opinions. This podcast is presented for exploratory purposes only. Published content is not intended to be used for preventing, diagnosing, or treating a specific illness. If you have, or suspect you may have, a health-care emergency, please contact a qualified health care professional for treatment.

Hey Heal Squad! If you've been confused, overwhelmed, or just a little skeptical about everything you're hearing about GLP-1 medications right now, ya might want to listen to this one! Today Maria sits down with Dr. Fatima Cody Stanford. She is an Associate Professor of Medicine at Harvard Medical School and Massachusetts General Hospital, and one of fewer than 15 physicians in the entire country who has completed more than one year of fellowship training specifically in obesity medicine. Maria first met Dr. Fatima at a Patriots game in Boston, and what struck her wasn't just the credentials,  it was how differently she talked about weight, the human body, and the people she treats. Literally, this became a true eye-opening science conversation about the GLP-1 space. Dr. Fatima breaks down what a GLP-1 actually is, why fat is literally an organ in the body, how our brains regulate weight through specific biological pathways, and why genetics, circadian rhythm, trauma, and environment all play a role in why some people's bodies hold onto weight no matter what they do. Then the conversation took a turn that genuinely surprised us. Dr. Fatima reveals that GLP-1 receptors exist throughout the entire body (not just in the gut, like most of us think!). which is why these medications are already being approved for conditions far beyond weight loss. Take a listen, it's a great conversation before you form any opinion. Enjoy! HEALERS & HEAL LINERS GLP-1s Are Not a Trend — They're a 20-Year Story: Dr. Fatima explains why they've been in development and clinical use for over two decades, and why the reason we're hearing about them now comes down to one thing — potency. The science didn't change. The strength finally caught up. Obesity Is a Disease, Not a Decision: One of the most powerful moments in this episode is when Dr. Fatima dismantles the idea that weight is simply about discipline. From genetics and brain signaling to circadian rhythm disruption and weight-promoting medications, she lays out the real biology behind why people carry excess weight. Your Body Is Fighting Back — On Purpose: Physical activity helps you maintain your weight, but it does not help you drop it. She explains exactly why the body defends its set point and what it actually takes to change it. Join us at our Canyon Ranch 2026 Retreat: https://www.canyonranch.com/lenox/retreats/heal-retreat-maria-menounos HEAL SQUAD SOCIALS IG: https://www.instagram.com/healsquad/ TikTok: https://www.tiktok.com/@healsquadxmaria HEAL SQUAD RESOURCES: Heal Squad Website:https://www.healsquad.com/ Heal Squad x Patreon: https://www.patreon.com/HealSquad/membership Maria Menounos Website: https://www.mariamenounos.com My Curated Macy's Page: https://stylecrew.macys.com/@mariamenounos EMR-Tek Red Light: https://emr-tek.com/discount/Maria30 for 30% off Airbnb: https://www.airbnb.com/host GUEST RESOURCES: Follow Dr. Fatima on Instagram: https://www.instagram.com/askdrfatima/?hl=en More info on Dr Fatima here: https://askdrfatima.com/ ABOUT MARIA MENOUNOS: Emmy Award-winning journalist, TV personality, actress, 2x NYT best-selling author, former pro-wrestler and brain tumor survivor, Maria Menounos' passion is to see others heal and to get better in all areas of life. ABOUT HEAL SQUAD x MARIA MENOUNOS: A daily digital talk-show that brings you the world's leading healers, experts, and celebrities to share groundbreaking secrets and tips to getting better in all areas of life. DISCLAIMER: This Podcast and all related content (published or distributed by or on behalf of Maria Menounos or http://Mariamenounos.com and http://healsquad.com) is for informational purposes only and may include information that is general in nature and that is not specific to you. Any information or opinions provided by guest experts or hosts featured within website or on Company's Podcast are their own; not those of Maria Menounos or the Company. Accordingly, Maria Menounos and the Company cannot be responsible for any results or consequences or actions you may take based on such information or opinions. This podcast is presented for exploratory purposes only. Published content is not intended to be used for preventing, diagnosing, or treating a specific illness. If you have, or suspect you may have, a health-care emergency, please contact a qualified health care professional for treatment.