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In this all-new episode, Harvard Medical School professor Dr. Anahita Dua joins psychologists Dr. John Gartner and Dr. Harry Siegel to navigate today's turbulent political landscape. Now on our 55th show, we pull no punches as we expose the full weight of Trump's cognitive decline, malignant narcissism, and the dangerous impact these traits have on our democratic institutions. Be sure to subscribe wherever you get your podcasts: Our site Subscribe on iTunes Subscribe on Spotify Subscribe on Amazon Music Subscribe on iHeartRadio We'll break down Trump's escalating authoritarian impulses—illustrated by the recent deployment of the National Guard in Los Angeles. This isn't a shock tactic; it's the predictable outgrowth of his autocratic ambitions. By twisting the truth and firing off false narratives, Trump and his cronies are setting the stage for repressive, martial law–style measures. The psychologists make it clear: we must stay alert if we're going to prevent this slide into tyranny. The conversation gets real as they draw stark parallels between historical dictatorships and Trump's reckless leadership. We hear about his impulsive decisions, glaring cognitive lapses, and the chaotic, almost self-destructive nature of his policies. Their message is blunt: Trump's chronic dishonesty and erratic behavior aren't just quirks—they're a fundamental threat to our democratic norms. Adding fuel to the fire, the episode features an eye-opening discussion with Dr. Aida Dua of Harvard Medical School. Dr. Dua lays it out: funding cuts aren't just numbers on a balance sheet—they represent a deliberate effort to dismantle American scientific innovation and global leadership. Dr. Siegel explains how these cuts risk stifling the very breakthroughs that keep our nation on the cutting edge of medicine and technology. Wrapping up, we take a close look at the public's response to Trump's warped governance. The roaring success of the “No Kings” rallies show a growing, collective cry for real democracy. Even amid the oppressive actions of ICE agents and the shocking assassination of a Minnesota politician, the steadfast resolve of peaceful protestors gives these psychologists—and all of us—a glimmer of cautious hope. Dr. Gartner and Dr. Siegel don't just analyze the mess—they issue a powerful call to action. They urge you to stay informed, be relentless in your scrutiny, and never back down from defending what's right. After all, if you have a platform, you have a responsibility to wield it in the fight against toxic leadership. Don't miss this riveting episode of Shrinking Trump as we expose the psychological underpinnings of one of the most dangerous political eras in our history. Subscribe now wherever you get your podcasts—on our site, iTunes, Spotify, Amazon Music, and iHeartRadio. Stay informed, stay engaged, and join us as we continue to unravel the truth behind this defining moment. Learn more about your ad choices. Visit megaphone.fm/adchoices
Join the conversation by letting us know what you think about the episode!We're joined this week by Dr. Uche Blackstock to discuss her memoir Legacy: A Black Physician Reckons with Racism in Medicine. Legacy is more than an account of Dr. Blackstock's journey to and in healthcare, it is also a love letter to her mother (the "original" Dr. Blackstock) and her community. As you can hear in our conversation, Legacy is also a wakeup call to all who read it, especially those in healthcare, that racism is more than unjust - it can be deadly. Dr. Blackstock received both undergraduate and medical degrees from Harvard University, making her and her twin sister, Oni, the first Black mother-daughter legacy graduates from Harvard Medical School. As an ER physician, and later as a professor in academic medicine, Dr. Blackstock became profoundly aware of the systemic barriers that Black patients and physicians continue to face.Dr. Blackstock's generational memoir, LEGACY: A Black Physician Reckons with Racism in Medicine, at once a searing indictment of our healthcare system, a generational family memoir, and a call to action, is Dr. Blackstock's odyssey from child to medical student to practicing physician—to finally seizing her own power as a health equity advocate against the backdrop of the pandemic and the Black Lives Matter movement.Dr. Uché Blackstock is the founder and Chief Advisor of Advancing Health Equity (AHE), founded in 2019 with the mission of partnering with healthcare organizations to dismantle racism in healthcare and to close the gap in racial health inequities. Advancing Health Equity has helped major companies, hospitals, and health systems create strategic plans for promoting equitable health care moving forward.Where to find Dr. Blackstock:Websites: www.ucheblackstock.com, www.advancinghealthequity.comIG: ucheblackstockmdLinkedIn: Uché BlackstockX: uche_blackstockSupport the showBe part of the conversation by sharing your thoughts about this episode, what you may have learned, how the conversation affected you. You can reach Raquel and Jennifer on IG @madnesscafepodcast or by email at madnesscafepodcast@gmail.com.Share the episode with a friend and have your own conversation. And don't forget to rate and review the show wherever you listen!Thanks!
My guest today is someone whose work has shaped the very code of modern biology, and whose vision continues to ripple across fields as vast as genomics, synthetic biology, age reversal, and artificial intelligence.Dr. George Church is a a true pioneer, Professor of Genetics at Harvard Medical School,a molecular engineer, chemist and serial entrepreneur as the co-founder of more than 50 biotech companies. He has helped invent many of the technologies that now define the genomic era, from CRISPR optimization to DNA data storage, and he was one of the first humans to ever publicly share his full genome and medical history.In this conversation, we explore the edge where science meets spirit.We talk about synthetic biology as a modern myth, DNA as a vessel of intelligence, and what it means to engineer life with intention. We dive into radical transparency, longevity research, AI collaboration, and the philosophical gravity of rewriting the arc of aging.This episode is not just about technology. It is about becoming.It is about asking: What does it mean to choose our evolution, consciously, ethically, and with awe.Episode highlights:00:04:30 – Sleep states and engineered serendipity: tapping creativity through unconscious rhythms00:06:30 – Synthetic biology as a modern myth: Promethean fire and the sacred aesthetic of science00:08:30 – DNA as memory, medium, and myth: encoding images in bacterial genomes00:10:00 – Is DNA a vessel of intelligence beyond biology?00:13:30 – Preserving culture in encoded DNA: who might decode it in the far future?00:16:00 – Are we alone in the universe? Dr. Church's speculative yet grounded view00:18:30 – What should we preserve for the next million years? The humility of legacy00:21:00 – DNA as sacred text: what it teaches us about identity, ancestry, and consciousness00:24:00 – Radical transparency: the Personal Genome Project and sharing his own genome00:29:00 – Rethinking consent, privacy, and research ethics in human genomics00:32:00 – From printing press to gene sequencers: the dawn of programmable biology00:33:30 – From slowing aging to redesigning it: reprogramming human cells and organs00:36:00 – How smarter gene, cell, and organ therapies could surpass pharmaceuticals00:40:00 – Personalized vs. generic medicine: the case for affordable global health00:43:30 – Aging as a treatable condition: tackling multiple pathways at once00:46:30 – Ethical and spiritual questions at the threshold of biological reinvention00:49:00 – The risks of artificial general intelligence vs. the promise of scientific AI00:52:30 – Why narrow scientific AI (like protein design) offers real-world breakthroughs00:54:30 – Will synthetic intelligence ever hold ethical responsibility?00:55:00 – Final reflections: safety, accessibility, and helping humanity fulfill its potentialResources mentioned:WebsitesWyss Institute: https://wyss.harvard.edu/team/core-faculty/george-church/Harvard Department of Genetics: https://icgd.bwh.harvard.edu/team/george-churchBiophysics at Harvard: https://biophysics.fas.harvard.edu/people/george-m-churchChurch Lab:
Dr. Uma Naidoo founded and directs the first hospital-based Nutritional Psychiatry Service in the United States. She is the Director of Nutritional and Lifestyle Psychiatry at Massachusetts General Hospital (MGH) & Director of Nutritional Psychiatry at MGH Academy while serving on the faculty at Harvard Medical School. She was considered Harvard's Mood Food Expert and has been featured in the Wall Street Journal. Dr. Naidoo is also the national bestselling author of This Is Your Brain on Food and her newest book, Calm Your Mind with Food is available now. In this fascinating rerun episode (first aired in 2020), Erin and Dr. Naidoo discuss her 2020 book, This Is Your Brain On Food. Key Topics: * Dr. Naidoo's journey as a psychiatrist and professional chef * How what we eat affects our brain * The origin of the gut/brain connection * The rise of mental health concerns * Food to avoid for mental well-being * Inflammatory foods * Orthorexia and food obsession * How to add more diversity in your diet * The impact of caffeine and alcohol on mental health Join Erin's monthly mailing list to get health tips and fresh meal plans and recipes every month: https://mailchi.mp/adde1b3a4af3/monthlysparksignup Preorder Erin's new book, Live Beyond Your Label, at erinbkerry.com/upcomingbook/
My conversation with Dr Dua begins at about 35 mins Stand Up is a daily podcast. I book,host,edit, post and promote new episodes with brilliant guests every day. This show is Ad free and fully supported by listeners like you! Please subscribe now for as little as 5$ and gain access to a community of over 750 awesome, curious, kind, funny, brilliant, generous souls Healthcare For Action was founded in 2022 to support healthcare workers running for Congress. Dr. Anahita Dua, Chair of Healthcare for Action, is a Vascular Surgeon at Massachusetts General Hospital and an Associate Professor of Surgery at Harvard University. As a surgeon, she knows that in order to get things done and save lives, the surgery team has to work together and take action. Our politics shouldn't be any different. In 2023, Healthcare For Action merged with Doctors In Politics, founded in 2020 by a group of physicians specializing in psychiatry, family medicine, OBGYN, and neurology. They were committed to patient-centered and equitable political change at all levels of government and grew to a membership of nearly 10,000. We believe fundamentally that all policy is health policy. There are too many existential threats facing our democracy. From reversing climate change, preserving access to abortion, and curbing the epidemic of gun violence we must take action now and play the long game. From acute care to prevention, healthcare workers know how to get the job done. That is the guiding vision of the largest Democratic healthcare workers PAC in the country - Join our community at Healthcare For Action! Anahita Dua, MD, MS, MBA, FACS, is a vascular surgeon at Massachusetts General Hospital and an associate professor of Surgery at Harvard Medical School. At Mass General, she is the director of the Vascular Lab, co-director of the Peripheral Artery Disease Center and Limb Evaluation and Amputation Program (LEAPP), associate director of the Wound Care Center, director of the Lymphedema Center and associate director of the Vascular Surgery Clerkship and director of clinical research for the division of vascular surgery. She specializes in advanced endovascular (minimally invasive) and traditional (open) limb salvage techniques for treating peripheral arterial disease and critical limb ischemia, diabetic limb disease, aortic disease, carotid disease, thoracic outlet syndrome and venous disease. Dr. Dua completed her vascular surgery fellowship at Stanford University Hospital, her general surgery residency at the Medical College of Wisconsin and her medical school in the United Kingdom. She has also completed a master's degree in trauma sciences, a master's in business administration in health care management and has a certificate in health economics and outcomes research as well as a certificate in drug and device development from the Massachusetts Institute of Technology. She is board-certified in vascular surgery, general surgery and advanced wound care and management. Dr. Dua has published over 140 peer reviewed papers and has edited five vascular surgery medical textbooks. She serves on multiple national vascular surgery committees through the Society for Vascular Surgery and other vascular organizations including the South Asian-American Vascular Society and American College of Surgeons. Dr. Dua's lab focuses on anticoagulation and biomarkers that are predictive of thrombosis and hemostasis in patients that have undergone revascularization. She is interested in creation precision, point of care medical approaches to anticoagulation for patients post revascularization. Her clinical and outcomes research focuses primarily on diseases involving peripheral vascular disease, limb salvage and critical limb ischemia. She is part of a technology development team that creates tools to increase walking distance and wound healing while decreasing pain in patients with peripheral vascular disease. Dr. Dua is also involved heavily in surgical outcomes-based research using large medical databases to generate both quality outcomes and cost effectiveness data. Dr. Dua is a self-described animal lover and rescuer of pitbulls. At one point, she housed 14 pitbull puppies and their mother at once. Nowadays, her spare time is spent with her husband, son, daughter and dog Leo. Join us Monday and Thursday's at 8EST for our Bi Weekly Happy Hour Hangout! Pete on Blue Sky Pete on Threads Pete on Tik Tok Pete on YouTube Pete on Twitter Pete On Instagram Pete Personal FB page Stand Up with Pete FB page All things Jon Carroll Follow and Support Pete Coe Buy Ava's Art Hire DJ Monzyk to build your website or help you with Marketing
Dr. Luiz E. Bertassoni is the founding director of the Knight Cancer Precision Biofabrication Hub and Professor in the Division of Oncological Sciences at the Knight Cancer Institute, where he is also co-section head for Discovery and Translational Oncology. He is also faculty in the Department of Biomedical Engineering, the Cancer Early Detection Advanced Research (CEDAR) Center, and the Oregon Health and Sciences University (OHSU) School of Dentistry. Luiz is co-founder of 2 biotech spin-off companies which resulted from his work on cancer research and regenerative medicine: he is Co-Founder and Chief Technology Officer of HuMarrow and Co-Founder and Chief Medical Officer of RegendoDent. Outside of science, Luiz is a big fan of surfing, and he enjoyed frequent trips to the beach while completing his PhD in Sydney, Australia, and a postdoctoral fellowship in San Francisco, California. In addition to spending time in the water, Luiz loves music. He is a singer-songwriter who plays various instruments, including guitar, drums, bass, and piano. In his research, Luiz applies engineering tools to biology to build human tissues in the lab. The goal of Luiz's lab is to create new models to better understand cancers and develop methods to regenerate lost or damaged tissues. Luiz was awarded his Doctor of Dental Surgery (DDS) degree from the Pontifical Catholic University of Parana in Brazil. Afterwards, he conducted postdoctoral research at the University of California, San Francisco. He then enrolled in a graduate program and received his PhD in Biomaterials from the University of Sydney. Next he accepted a postdoctoral fellowship in Harvard Medical School and MIT's joint program in Health Sciences and Technology. He served on the faculty at the University of Sydney before joining the faculty at OHSU in 2015. His work on vascular bioprinting was listed in the top 100 research discoveries by Discover Magazine, and he has received over 30 national and international research awards, including the Medical Research Foundation New Investigator award, the Silver Family Faculty Innovation award, and many others. In this interview, Luiz shares more about his life and science.
******Support the channel******Patreon: https://www.patreon.com/thedissenterPayPal: paypal.me/thedissenterPayPal Subscription 3 Dollars: https://tinyurl.com/ybn6bg9lPayPal Subscription 5 Dollars: https://tinyurl.com/ycmr9gpzPayPal Subscription 10 Dollars: https://tinyurl.com/y9r3fc9mPayPal Subscription 20 Dollars: https://tinyurl.com/y95uvkao ******Follow me on******Website: https://www.thedissenter.net/The Dissenter Goodreads list: https://shorturl.at/7BMoBFacebook: https://www.facebook.com/thedissenteryt/Twitter: https://x.com/TheDissenterYT This show is sponsored by Enlites, Learning & Development done differently. Check the website here: http://enlites.com/ Dr. Charlotte Blease is an interdisciplinary health researcher at the Department of Women's and Children's Health at Uppsala University, Sweden, and the Digital Psychiatry Division at the Beth Israel Deaconess Medical Center at the Harvard Medical School. She is a former Fulbright Scholar and a winner in 2012 of the UK-wide BBC Radio 3's New Generation Thinkers Competition. Dr. Blease has written extensively about the ethics of placebo and nocebo effects. Her research has been profiled by international news outlets including The Washington Post, The Guardian, and The Sydney Morning Herald. She is coauthor of The Nocebo Effect: When Words Make You Sick. In this episode, we focus on The Nocebo Effect. We start by talking about the placebo effect and the nocebo effect. We discuss how the nocebo effect is produced psychologically, whether it is “all in the head”, how it is produced in a clinical context, how to distinguish between “real” side effects of treatments and nocebo effects, and whether words can produce harm. We also discuss whether psychotherapy is mostly placebo. Finally, we talk about the side effects and nocebo effects of the COVID-19 vaccine, nocebo effects in public health and medical ethics, and how to reduce the nocebo effect.--A HUGE THANK YOU TO MY PATRONS/SUPPORTERS: PER HELGE LARSEN, JERRY MULLER, BERNARDO SEIXAS, ADAM KESSEL, MATTHEW WHITINGBIRD, ARNAUD WOLFF, TIM HOLLOSY, HENRIK AHLENIUS, FILIP FORS CONNOLLY, ROBERT WINDHAGER, RUI INACIO, ZOOP, MARCO NEVES, COLIN HOLBROOK, PHIL KAVANAGH, SAMUEL ANDREEFF, FRANCIS FORDE, TIAGO NUNES, FERGAL CUSSEN, HAL HERZOG, NUNO MACHADO, JONATHAN LEIBRANT, JOÃO LINHARES, STANTON T, SAMUEL CORREA, ERIK HAINES, MARK SMITH, JOÃO EIRA, TOM HUMMEL, SARDUS FRANCE, DAVID SLOAN WILSON, YACILA DEZA-ARAUJO, ROMAIN ROCH, DIEGO LONDOÑO CORREA, YANICK PUNTER, CHARLOTTE BLEASE, NICOLE BARBARO, ADAM HUNT, PAWEL OSTASZEWSKI, NELLEKE BAK, GUY MADISON, GARY G HELLMANN, SAIMA AFZAL, ADRIAN JAEGGI, PAULO TOLENTINO, JOÃO BARBOSA, JULIAN PRICE, HEDIN BRØNNER, DOUGLAS FRY, FRANCA BORTOLOTTI, GABRIEL PONS CORTÈS, URSULA LITZCKE, SCOTT, ZACHARY FISH, TIM DUFFY, SUNNY SMITH, JON WISMAN, WILLIAM BUCKNER, PAUL-GEORGE ARNAUD, LUKE GLOWACKI, GEORGIOS THEOPHANOUS, CHRIS WILLIAMSON, PETER WOLOSZYN, DAVID WILLIAMS, DIOGO COSTA, ALEX CHAU, AMAURI MARTÍNEZ, CORALIE CHEVALLIER, BANGALORE ATHEISTS, LARRY D. LEE JR., OLD HERRINGBONE, MICHAEL BAILEY, DAN SPERBER, ROBERT GRESSIS, JEFF MCMAHAN, JAKE ZUEHL, BARNABAS RADICS, MARK CAMPBELL, TOMAS DAUBNER, LUKE NISSEN, KIMBERLY JOHNSON, JESSICA NOWICKI, LINDA BRANDIN, GEORGE CHORIATIS, VALENTIN STEINMANN, ALEXANDER HUBBARD, BR, JONAS HERTNER, URSULA GOODENOUGH, DAVID PINSOF, SEAN NELSON, MIKE LAVIGNE, JOS KNECHT, LUCY, MANVIR SINGH, PETRA WEIMANN, CAROLA FEEST, MAURO JÚNIOR, 航 豊川, TONY BARRETT, NIKOLAI VISHNEVSKY, STEVEN GANGESTAD, TED FARRIS, ROBINROSWELL, AND KEITH RICHARDSON!A SPECIAL THANKS TO MY PRODUCERS, YZAR WEHBE, JIM FRANK, ŁUKASZ STAFINIAK, TOM VANEGDOM, BERNARD HUGUENEY, CURTIS DIXON, BENEDIKT MUELLER, THOMAS TRUMBLE, KATHRINE AND PATRICK TOBIN, JONCARLO MONTENEGRO, NICK GOLDEN, CHRISTINE GLASS, IGOR NIKIFOROVSKI, PER KRAULIS, AND BENJAMIN GELBART!AND TO MY EXECUTIVE PRODUCERS, MATTHEW LAVENDER, SERGIU CODREANU, ROSEY, AND GREGORY HASTINGS!
Thoughts on Record: Podcast of the Ottawa Institute of Cognitive Behavioural Therapy
Comments or feedback? Send us a text! Digital media is changing the way young people experience—and express—mental health struggles, particularly depression. Child and adolescent psychiatrist, Dr. Meredith Gansner, joins us to discuss themes in her new book Teen Depression Gone Viral.
Send us a textDr. Koren reflects on conversations with Harvard Medical School classmates who shared stories about struggling to navigate the healthcare system despite their medical training. Clinical trials provide valuable structure and support to help patients navigate healthcare complexities, offering personalized attention often unavailable in traditional medical settings.• Harvard Medical School graduates find healthcare navigation difficult, highlighting challenges for average patients• Case study of 78-year-old with heart failure who was accidentally overdosed on medications after discharge• Clinical trials break down complex health information into clear protocols • Research coordinators help patients understand treatments and communicate with other providers• Studies available for congestive heart failure patients, including both types of heart failure• Harvard classmates will be featured on upcoming MedEvidence episodesVisit EncoreDocs.com to learn more about participating in clinical trials, or call 904-730-0166. For reliable medical information, check out MedEvidence.com - the truth behind the data, a better alternative to "Dr. Google."Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!
In this episode of PeDRA Pearls, we host a powerful conversation featuring the Gorlin Syndrome Alliance (GSA). Join us as we delve into the world of Gorlin Syndrome through the heartfelt narrative of Taylor Hodge, who recounts her family's journey following her son's diagnosis at just 18 months old. Joined by Dr. Elena Hawryluk of Harvard Medical School, the discussion sheds light on current research gaps and future directions in the field. Meredith Weiss, Executive Director of the GSA, also contributes, highlighting the essential patient support programs offered by the GSA and the organization's unwavering commitment to research and collaboration. This episode offers a blend of personal insight and professional expertise, providing listeners with a comprehensive understanding of Gorlin Syndrome and the ongoing collaborative efforts to support those affected.
In this keynote episode, Professor Sebastian Schneeweiss from Harvard Medical School shares groundbreaking insights from his extensive research into emulating randomized controlled trials (RCTs) using real-world data (RWD). Recorded live at The Effective Statistician Conference 2024, this talk explores whether non-randomized studies based on electronic health records and claims data can reach conclusions as reliable as those from traditional RCTs. Prof. Schneeweiss, also Chief of the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women's Hospital, walks us through the RCT DUPLICATE project, a major FDA-funded initiative that evaluated whether regulatory decisions could be replicated through high-quality real-world evidence (RWE). From the successes to the limitations—and everything in between—this episode is packed with lessons for statisticians, regulators, and pharmaceutical leaders interested in the future of data-driven healthcare decisions.
MOPs & MOEs is powered by TrainHeroic!To continue the conversation, join our Discord! We have experts (including Rachele!) standing by to answer your questions.When we hit record on this conversation, we thought it would be a single episode focused on bridging the gap between academia and practice, but we quickly realized that Rachele had a wealth of information to share. This will be part 1 of a 3 part series, and it all revolves around science communication. Some specific topics include the roles of different professions within human performance, lifestyle medicine, supplements, and the challenges of making sure research is relevant and useful.Rachele Pojednic, PhD, EdM, FACSM, is the Director of Scientific Research & Education at Restore Hyper Wellness, an Adjunct Lecturer at Stanford University and the Director of Education at Stanford Lifestyle Medicine. In addition, she serves as a Research Associate at the Institute of Lifestyle Medicine at Harvard Medical School and is an award-winning Instructor at the Harvard Extension School. Previously, she was a tenure-track faculty member at Norwich University and Simmons University.For the past decade, Dr Pojednic's work has examined nutrition, supplementation and physical activity interventions on muscle physiology, performance and recovery, as well as muscle related chronic disease. She has received research funding from the National Institutes of Health (NIH) National Heart Lung and Blood Institute (NHLBI) and the Vermont Biomedical Research Network (VBRN) an NIH IDeA Network of Biomedical Research Excellence (INBRE) program. She has published extensively on vitamin D and cannabidiol (CBD) supplementation and their effects on skeletal muscle in health and disease, muscle physiology and aging with a focus on sarcopenia, physiologic metrics of muscle recovery in warfighters, the effects of nutrition and exercise interventions on diseases such as obesity and type 2 diabetes, and educational models for healthcare professionals focused on nutrition and exercise.Dr. Pojednic received her PhD in Biochemical and Molecular Nutrition & Exercise Physiology from Tufts University. She also holds a Masters in Education in Physical Education and Coaching from Boston University and a BS in Cardiopulmonary and Exercise Science from Northeastern University. She holds a Certified Strength and Conditioning Specialist (CSCS) certification from National Strength and Conditioning Association (NSCA) and is board certified Health Coach from the National Board of Health and Wellness Coaches (NBHWC).
In this episode of I Thought You'd Like to Know This, Too, ITEST presents a webinarentitled "Bioethics & AI as Human Flourishing: Where Catholic & Orthodox Social Teaching meet in One Christian Social Ethos" (June 14, 2025)Dr. Constantine PsimopoulosBIOETHICS AND AI AS HUMAN FLOURISHING: WHERE CATHOLICS AND ORTHODOX MEET IN ONE CHRISTIAN SOCIAL ETHOSConstantine Psimopoulos is a Professor (Adj.) of Bioethics at Hellenic College Holy Cross Greek Orthodox School of Theology, teaching Christian Ethics and Social Ministries and is on the faculty at Harvard's Initiative on Health, Spirituality and Religion, of which he is also Senior Program Administrator, and the Human Flourishing program. He has another Academic research appointment in Global Health and Social Medicine and the Center for Bioethics at Harvard Medical School. At Harvard, he co-teaches the course Religion and Public Health and a new required module taught to all MD/PhD students. Constantine serves as the Director of the Division of Bioethics of the Orthodox Academy of Crete (Ecumenical Patriarchate), and as an Invited Member to the Inaugural National Committee on AI – Artificial Intelligence (and Theology) of the Greek Orthodox Archdiocese of America.AbstractThis presentation draws a comparison between Catholic social teaching and the Social ethos of the Orthodox church. Both traditions have some parallels in the way they approach AI, from a bioethical perspective that addresses social justice. The document ‘For the Life of the World' (F.L.O.W.) of our Ecumenical Patriarchate of Constantinople, emphasizes that science and technology are a wonderful product of a God-given human creativity, and that “the desire for scientific knowledge flows from the same wellspring as faith's longing to enter ever more deeply into the mystery of God.” It is an imperative to use AI for Human Flourishing. From a Christian bioethical lens, science and technology, and in particular Artificial Intelligence (AI), can serve as one concrete example of how this can be addressed.Fr. Michael Baggot, LCProgramming with Purpose: Guiding AI through Catholic Social TeachingFr. Michael Baggot is Legionary of Christ, an Associate Professor of Bioethics at the Pontifical Athenaeum Regina Apostolorum, and an Invited Professor of Theology at the Pontifical University of St. Thomas Aquinas (the Angelicum) and the Catholic Institute of Technology (CatholicTech). He also serves as a professor for the Joint Diploma in Leadership: Service through Virtues and the Catholic Worldview Fellowship summer program. In addition, Fr. Michael is a Research Scholar at the UNESCO Chair in Bioethics and Human Rights and a member of the Scholarly Advisory Board for Magisterium AI. He is also a fellow of the Fr. James L. Heft, SM Generations in Dialogue program at the Institute for Advanced Catholic Studies at the University of Southern California.AbstractAs an expert in humanity, the Catholic Church is deeply interested in the AI technologies that are shaping family life, education, medicine, religious practice, and other key aspects of social life. The presentation draws on the social doctrine of the Catholic Church to highlight the virtues and social structures most conducive to using AI tools to promote human flourishing. It gives special attention to the influence of AI companion systems on the loneliness epidemic and the quest for social connections. The conference also examines the significance of ecumenical dialogue, interreligious dialogue, and dialogue with secular traditions in addressing the perennial philosophical questions that emerging technologies raise.Bioethics and AI as Human Flourishing: Where Catholic and Orthodox Social Teaching meet in One Christian Social Ethos - Institute for Theological Encounter with Science and Technology
This week we speak with Assistant Professor of Pediatrics at Harvard Medical School, Dr. Audrey Dionne about a recent work she co-authored on the topic of outcomes of ablation in the early postoperative period following congenital heart surgery. Who is a candidate for this intervention and what were the outcomes? How commonly were serious complications encountered and how successful were these procedures? Dr. Dionne reviews these and other aspects of this novel review this week. https://doi.org/10.1016/j.hrthm.2024.08.061
Maria Artunduaga is the founder & CEO of Samay, the winner of the 2024 MedTech Innovator accelerator, as well as a groundbreaking physician, scientist, and inventor. Maria discusses her inspiring journey from a small town in Columbia to leading a top MedTech company in the US. After pivoting away from plastic surgery training, she channeled her efforts into creating Sylvee, an AI wearable sensor for COPD patients. Maria shares her relentless determination, innovative problem-solving strategies, and the creation of a company culture that emphasizes learning and diversity. Guest links: https://www.samayhealth.com/home | https://www.linkedin.com/in/drartunduaga/ Charity supported: ASPCA Interested in being a guest on the show or have feedback to share? Email us at theleadingdifference@velentium.com. PRODUCTION CREDITS Host: Lindsey Dinneen Editing: Marketing Wise Producer: Velentium EPISODE TRANSCRIPT Episode 057 - Maria Artunduaga [00:00:00] Lindsey Dinneen: Hi, I'm Lindsey and I'm talking with MedTech industry leaders on how they change lives for a better world. [00:00:09] Diane Bouis: The inventions and technologies are fascinating and so are the people who work with them. [00:00:15] Frank Jaskulke: There was a period of time where I realized, fundamentally, my job was to go hang out with really smart people that are saving lives and then do work that would help them save more lives. [00:00:28] Diane Bouis: I got into the business to save lives and it is incredibly motivating to work with people who are in that same business, saving or improving lives. [00:00:38] Duane Mancini: What better industry than where I get to wake up every day and just save people's lives. [00:00:42] Lindsey Dinneen: These are extraordinary people doing extraordinary work, and this is The Leading Difference. Hello, and welcome back to another episode of The Leading Difference podcast. I'm your host Lindsey, and I am delighted to welcome as my guest today, Maria Artunduaga. Maria is a physician, scientist, and inventor with 60 plus prizes, including becoming the first woman to lead a US LATAM company to win MedTech Innovator, the world's most competitive accelerator for medical technology surpassing over 1300 global companies. A top 1% student in Columbia, her country of birth, she relocated to the US to pursue plastic surgery training, but abandoned it to dedicate herself to solve the problem that killed her grandmother-- a lack of home technologies that can detect COPD exasperations early. Maria has raised 5.2 million, almost 60% in non-dilutive capital from NSF and NIH to build Sylvee, an AI wearable sensor that can provide COPD patients with continuous data on pulmonary functions similar to what continuous glucose monitoring sensors do for diabetic patients. Her invention has been featured by a hundred plus media outlets, including Forbes, TechCrunch, Bloomberg, Fierce Healthcare, and more. Before Samay, Maria completed postdoctoral studies in human genetics at Harvard Medical School, started a plastic surgery residency at the University of Chicago, and completed two master's degrees, one in global public health at the University of Washington, and another in translational medicine at the University of California at Berkeley and San Francisco. She lives in Mountain View, California with her husband, 2-year-old daughter, and four pets. In her free time, she enjoys flamenco dancing, bolero singing, traveling the world, and fostering diversity in and outside the workplace by mentoring underrepresented scientists and entrepreneurs. All right. Well, thank you so much for being here, Maria. I'm so excited to finally get a chance to speak with you. I'd love if you would share a little bit about your background and your career trajectory. What led you to MedTech? [00:02:40] Maria Artunduaga: Sure. So it's gonna be a little long and I'm gonna tell you everything about my life because the personal history is very important to me and for my company too. So, as you have noticed, I have an accent. So, I grew up in Columbia in a very small town in the southern part of the country. My parents were both doctors and I'm the oldest of four kids and two of us followed their lead. So my life in my city was pretty chill. Everyone knew everyone. I spent most of my days at a Catholic school studying very hard on weekends where I usually spent tagging along my parents to doctor events. One of the things that I really like to tell, it's how my parents work as entrepreneurs really shaped my life. They were real pioneers. They built in my hometown the first big clinic back in the eighties and the nineties. And my mom was the only woman in that group, and she actually was the CEO for a while, which was a big deal. She was the only woman in a partnership of 10 people. And watching them build that clinic, that hospital really taught me a lot about dealing with uncertainty and finding solutions. Every day we'll have supper or lunch and I'll just hear all of these challenges and stories, their struggles and how they solve things. Something that was, that is definitely super helpful in what I do now, right? So, and then I was 16 and after high school I moved to Bogota, the capital, which is up in the mountains, it's very cold. I got a scholarship 'cause I was always a very good student. You know, career I spent my last year, I spent nine months in the US. Honestly, coming to the US blew my mind. The technology that I got to see, the speed, effects on science, it was nothing like I've ever seen before, and that was true inspiration for me. So I knew that I had to come to the US. I needed to come back to learn from the best, of course. And it's interesting because my parents didn't want me to relocate to the US. I was the oldest. I was supposed to follow into their footsteps and obviously, like inherited that clinic, right? That hospital, we call it clinic, it's actually a hospital. And I was a very contrarian. I didn't listen to them. I told them, you know, I really wanna be where the best people are. And what I did was that I, it took me three years to save the money to come to the US, to get Harvard to actually sponsor me my visa because they wouldn't pay me for the first year. So I remember I had to save $30,000, which in pesos is significant. So back in 2007, so many years ago, I made it to Boston, and the original idea was that I wanted to become a pediatric plastic surgeon and bring that level of care back to Columbia. I spent four years of researching a genetic ear condition that's called microtia. And with that work, I was able to land a plastic surgery residency spot or position at the University of Chicago. And I shared this with a lot of people. I actually had a really negative experience. Things didn't go as planned. I actually faced discrimination. I eventually, you know, had to leave and I made the top choice to never ever go back into clinical practice. And I changed paths. I was 32 years old and yeah I decided to switch gears. I retrained into public health and tech. And then in 2016, I moved to the Bay Area where I am right now. And I got another scholarship to finish master's in translational medicine at UC Berkeley and UCSF. And during the courses that I took, some of them with business class etc., etc., I decided to found Samay in 2018. I really wanted to build something that would really make a difference in respiratory medicine. And this is where my grandmother comes. So my, the grandmother, my abuela, her name was Sylvia and she had Chronic Obstruct Pulmonary Disease or COPD and she's the reason behind my company. So, she often couldn't tell when her symptoms were getting worse. That's a huge problem. Catching the respiratory attacks, exacerbations is definitely key to keeping people outside of the hospitals, and obviously feeling their best to have a better quality of life. So, that's what we are trying to solve with a company, right? If we are able to catch those exacerbations even with a day or two notice in advance, right, that we can all make a difference. And so by missing these exacerbations, we are having really high expenses in hospitalizations and ER visits and the problem we trying to solve is that today technologies that are adequate enough to be used outside of the hospital because the ones that are considered to be the gold standard, they are very expensive. They are confined to their hospitals and they are very difficult to complete for the patient, especially when they're exacerbating. They need to blow out forcefully for about 10 seconds, 21 times. So what we are doing is, we are developing a sensor that makes it super simple for people to use it at home to track their lung function without doing those forceful maneuvers and ideally in the future to warm them, right? Like to let them know when things are starting to go south or obviously, you know, not going very well, and that's what it's all about. I mean, that's what we do with Sylvee right here. And it's wearable sensor and we have done significantly well over the past couple of years. We actually just won MedTech Innovator. [00:08:04] Lindsey Dinneen: Yeah. Significantly well over the last few years. Yes. So congratulations on that, and I want to dive into all of those exciting milestones in just a second. But I am, first of all, so inspired by your story. Thank you for just sharing that your resilience and your grit and your determination are really admirable. So thank you for sticking with something that was not easy, not an easy path. [00:08:29] Maria Artunduaga: I know. I know. [00:08:31] Lindsey Dinneen: It continues not to be, ironically, as we've kind of touched on before, but just going backward a little bit in your story. So I, it sounds to me like getting the opportunity to watch your parents have this incredible impact on their community and the healthcare and the opportunity is just so valuable for you. And even just learning about how your mom was the CEO and those kinds of things, did that help shape the idea for you that not only is entrepreneurship possible, is innovation and healthcare possible, but you can also be this in incredible leader as a woman in whatever capacity? I would just love to dive into that. [00:09:13] Maria Artunduaga: Yeah, it's super interesting, right? My mom really taught me a lot about leadership. She's a surgeon, so you can imagine how good of a leader she is in the operating room at home, everywhere, right? I mean, she's definitely the general, that's how I call her. And I honestly, I try to replicate, so my leadership and styles pretty much shaped by her. So I always call her my best role model whenever somebody asks me about the question, right? So I'm just like her. I lead from the front. I like setting the pace by working the hardest. So I really like to lead by example and I also, just like she did, and obviously because of her surgical training, I hold myself to a really high standard, and I expect everyone on my team to do the same. So people in my company know that I'm very strict, I'm very disciplined, and they know that from the beginning. It's so funny because when I interview all of them, at the final interviews with me, and I actually do the anti sale to join Samay. It's like, this is, these are all the reasons why you shouldn't join. I start describing myself as a very intense, obsessed CEO with insomnia, which I still have, because I really wanna make this work, right? So, yeah, I, ask them, and most of them say yes. I really like, I attract people that like challenges, especially intellectual challenges. So, yeah, to this point, most of them say yes. Some of them have obviously, you know, because probably too much. But at the same time, I tell them, "Look, this is going to be very hard in terms of the deliverables, the things that we're expecting from you." But at the same time, my goal is to not only help people with respiratory problems, I try to sell the company as a company where everyone that gets hired can be themselves and thrive. So, so for example, I tell them," Look, I'm trying to be the boss that I never had." And this goes obviously very tied to the very negative experience that I had during my surgical residency and even before, right? So, I never had a boss that really supported me, who recognize my true self and those characteristics as good things, right? So they always try to tone me down. I'm very energetic, as you can notice, and I'm also super ambitious. I'm really ambitious. I wanna do all of these great things. And they always thought that I was aiming for too much, especially for a woman. It's like, " You need to lean in, Maria. You need to behave." So I remember my residency, they were criticizing like, "Why are you behaving like this, Maria? Why are you asking so many questions? You're asking too many questions. You look more as an internal medicine doctor. Why are you always smiling, Maria? Why are you so happy?" So now, with everyone that I hire, what I try to do is that I focus on understanding their dreams and I try to figure out how this job is gonna help them get there. So if they wanna become a top engineer, maybe they wanna learn managerial skills, or they wanna run operations, or they eventually wanna become a founder themselves. So I try to create a partnership with them where they obviously help me succeed with the company, build Samay, but at the same time they get to do this personal growth. So it's extremely important that they get to place where they wanna be. [00:12:32] Lindsey Dinneen: Yeah, that's wonderful. And such a gift to your employees. And I also honestly, that sort of anti interview or whatever technique is brilliant because you do want it to be a fit for everyone, and it's so much better to have aligned expectations from the start. So, oh my goodness, that's so interesting. So, okay, so then. Speaking into that, how do you develop a company culture for yourself? You've learned from some pretty negative experiences, so obviously that's what not to do, but you know, as you're crafting your own company culture now, what kinds of things are sort of your core values, other than of course, your hard work and your excellence and holding yourself and others to high standards, but what kinds of things do have you developed that make it special to be where you are? [00:13:19] Maria Artunduaga: Yeah, I mean, that's a really good question. I'm very true to myself, and one of the things that I wanna do with Samay, it's I wanna create legacy. If you go to my WhatsApp, that's exactly the little logo or the slogan that's below my name: I'm creating or building my life's legacy. That's how I pitch myself. So I really wanna be remembered as someone that made healthcare more accessible, especially for the people that get left behind. So growing up in Columbia, I saw firsthand how unfair things will be and I wanted to change that. So that's how the values of Samay go, people first. I think legacy, it's extremely important, right? It's about getting those life changing tools and opportunities into the hands of people who really need them. And again, it's not necessarily, the group that we're building. It's the own experience of building a company with me, learning from the company, from the people that are working with. I really wanna make it accessible for people. And I wanna also be obviously a source of inspiration. You don't necessarily need to be this perfect person to be a CEO. You know, life is a struggle and that's totally fine. Just be very passionate about building legacy, right, your work and how you're impacting other people. And especially for me, I do a lot of work with women and minorities. I really wanna empower them to chase their dreams in science and technology. I really care about people. I don't know, I'm selfless about me. It's all about the others and creating legacy and being remembered. So, yeah, that's how I, that's how I roll. [00:14:59] Lindsey Dinneen: I love that. I love that. So speaking of you embracing the CEO role, when you first started your company, did you feel ready to step into this kind of position? Or was it something where you just were like, "You know what? I see the need. I know I can make a difference in this field. I'm gonna do it and I'll learn along the way." [00:15:19] Maria Artunduaga: No, not at all. And let, so there's a very good anecdote that I'm sharing. Again, back to all of these life changing experiences. I got into medtech because of, I don't know, somehow the planets got aligned, right? So I was doing a master's in public health because I thought that was going to be my real call, working for Gates in Seattle, because that's where I actually lived for about two years. Then I came to realize that it was very bureaucratic. It's very, was very slow. I have a type A personality. I really like to fix things very quick. I like to implement stuff. So I decided to do a second master's degree, and as I mentioned, here in Berkeley, I decided to join one of Atma METs minority programs for students, right? It's called SMDP. And I remember that was back in 2016, and they sent me to Minneapolis for the big conference. And that's where I got my first real taste of MedTech. And I remember watching the MedTech Innovator finals with Paul Grand. He was introducing the program, the finalist. I remember clearly seeing all of his pitches and how Green Sun Medical CEO won, and it was a game changer to me because when I saw them pitch, it was very exciting. You know, all these technologies, the many millions of people they could definitely impact, I saw that, and it clicked. I could turn the scientific ideas into something that helps millions in a way, the way how I would practice medicine, but in a more impactful way. So interesting story though. So the other thing that was very inspiring or at least that motivated me, I was the only person in the room who looked like me and spoke with an accent from South America, from Latin America. So it was like two reasons behind it. For me, it was I wanna be a medtech entrepreneur, but at the same time I wanna be able to break the glass ceiling, right? The first Latina physician CEO building a company that has hardware, software, and AI, this is what we actually do. And yeah, so it, it's mainly that. I really like challenges and I'm very motivated to show people that I can do things that might seem impossible or too difficult. So I really like showing people that anything is possible with a lot of hard work and determination. So yeah, that's mainly it. [00:17:47] Lindsey Dinneen: I love that. Embracing those challenges, running full steam at them and having that, I don't know, that gumption is fantastic too. And the desire, like... [00:17:57] Maria Artunduaga: Thank you. [00:17:57] Lindsey Dinneen: ...you said, to break through those ceilings and to represent and say, "No, it is possible." It is, and I love that. So, excellent. Okay, so can you share a little bit about the journey that the company has gone under recently and some of the really exciting milestones? I know there have been bumps and whatnot, but maybe some of the exciting things that have been developing and what you're looking forward to as you continue down the road. [00:18:24] Maria Artunduaga: Sure. I mean, whew. There are so many things that have been happening for the last couple of months. So it's been a long journey. It's been six years so far. Initially, you know, I wanted to build a company with an idea that was inspired, obviously, by the fact that I lost my grandmother to exacerbation and also because, at the time, I didn't know what I wanted to build. When I was doing an interview with a pulmonologist, what I realized was that I could actually build a technology that could be inspired by consumer devices, so hearing aids for example. And funny story is that my husband who is also Columbian, and went to MIT, he's been working at Google for over a decade and he's an auto engineer. He does a lot of things. He's very smart and he's one of the main architects. What I decided to do back then was, let's repurpose hearing aid technology by sending signals through the chest, and let's use the physical principle of acoustic resonance to understand what's going on inside of the lungs. And that's exactly what we are doing. We have 10 granted patents so far. We have 20 more pending on pulmonary so far. So we've done a lot of things. So we've tested that device on 450 people almost. All of our numbers of accuracy are over 90. Sensitivities and specificities are also between 82 to 98. Right now we are starting to see changes a few days before an exacerbation is actually diagnosed by a physician, which is extremely exciting. We have data from two people. Obviously it's a small sample size. We are following eight of them, and we're aiming to finish at 60 to hundred people in the next year or so. So that's our main goal. We've raised 5.2 million, 60% of that money is coming from grants, federal grants, and we just submitted a breakthrough designation to the FDA about a week ago, so fingers crossed, though, we get it right? There are a lot of things in the pipeline, things that are very exciting. Right now I'm super excited 'cause those six years were very hard. I was running a science project with my nails, getting money from grants, help from people who have known me forever. It was very hard for me to recruit a full-time CTO. So my husband has been helping me with some hours here and there. And we have right now 12 people in Columbia. So for developers, designers, clinical researchers, we are running most of our operations in Latin America because it's extremely, well, obviously cost efficient, and more importantly, we have access to people that are patients especially that are, that exacerbate more often. So we are to leverage all the different angles that we can get. [00:21:04] Lindsey Dinneen: Yeah. Wow. So lots of exciting things in the works and in the future, and oh my goodness, I'm so excited, can't wait to continue to celebrate all those wonderful accomplishments. So I'm curious, as you've taken this journey and even before with your other health experiences and finding this path, are there any moments all along the journey that really stand out to you as affirming, "Yes, I am in the right place at the right time, in the right industry." [00:21:31] Maria Artunduaga: Yeah, beyond the MedTech Innovator, the experience eight years ago, I mean, every day I find that this is the perfect fit for me. I always tell people, "Look, entrepreneurship is not for everyone. It really needs to be a fit of personality." So when I talked to my parents, because at the beginning they weren't very agreeable with the idea of me becoming an entrepreneur 'cause physicians don't do this, right? I was sort of like a black sheep of a family, 'cause my sister, she's successful and she's a pediatric radiologist as she's working for an academic center in, in Dallas. So, my personality, I'm Type A. I'm very anxious. I really like doing things super fast. I really like to get things done, right? So, I dunno if I picked the wrong career, probably could have done a better job as an engineer, as a scientist myself. So at heart, I'm a true scientist. That's what I really enjoy. I like practicing medicine, sort of miss it a little bit, but I'm more in the quest of solving questions and discovering, right? That's what really excites me. And then, every day is a new day when you're building a company. And the challenges that I have every day, all of the problems I have to solve, I really enjoy the process of solving them. And this is a little crazy. Who gets excited with problems, right? So, I don't know, that's probably me. So I guess every day, the moment I go home or that I go to sleep, I say, "This is perfect. I don't think I'll be as happy as I am right now if I had stayed medicine. I don't think so." [00:23:10] Lindsey Dinneen: Wow. And that says a lot. And that just affirms to you on a daily basis, "Yeah. I am doing what I'm supposed to be doing. That's wonderful. [00:23:17] Maria Artunduaga: Exactly. Right. It's like, yeah, I'm good at this thing. You know? I like solving problems. I got, I really enjoy the fires. I really like them. I's like, I don't know. I'm, yeah. I'm addicted to them. [00:23:30] Lindsey Dinneen: I love that. Well, and that is unusual, and I'm curious, do you? But it's a great thing. No, it's a wonderful thing. Yeah, no, absolutely. I love that. So, so when you're at finding yourself up against a problem, do you start with any particular kind of established framework? Do you like to just brainstorm solutions? How do you approach problem solving? [00:23:53] Maria Artunduaga: Gosh, this is a really good question. It's like, you know, if I had to teach something, right? So I'm very good at solving problems, at connecting different disciplines, right, to solve those issues. So for example, the way how I go about them, first of all, I don't get frustrated or too anxious about it. I always try to think first, right? And then, yeah, I start brainstorming. I'm very quick at thinking, my mind goes super quick. I have a whiteboard right behind me. I do a lot brainstorming on my own. I ask a lot of questions too. So I rely on a lot of people, and I get a lot of feedback on the way, how I think a problem needs to be solved. And obviously with time and experience, the older that you get, the better you become, right? So yeah, honestly, every problem is different. I just like seeing it from different angles, right? I'm very good with social stuff. I'm very good with arts too. I really like doing science, learning a about engineering. I really like different ways of solving problems. For example, I remember that I we had this NIH grant and we were working collaboration with a big, famous academic center right here. And things weren't working very well. That was through during a pandemic and I was getting charged things that we actually didn't approve. So things were getting a little awkward. I decided to finalize that agreement. But then I got through this situation that I had no access to patients here in the States, and at the time, I didn't have my clinical site in Columbia opened up. So what I did was the craziest thing, which is what I did, was that I bought an $80,000 machine and I came into an agreement with a friend from medical school who has a pulmonary practice in South Florida, one of the largest pulmonary practices. He's a partner with nine other guys, and they see probably a hundred patients every day. Can you imagine that? So respiratory patients, and I told him, "Look, I don't have any money to pay your rent, but I'm gonna give you equity for that rent, and you're gonna use this machine from Monday through Thursday, and I'm going to test your patients from Friday to Saturday. And I'm going to bring people, I'm going to become my own CRO, right? So I'm gonna bring people, doctors, from Columbia on a J1 visa as a research scholar visa. I'm gonna train them and I'm gonna get them to do the recruitment, review everything, test the patients. We are going to become our own CROs, and we are going to do as many people as we can every single week." So we were able to do 430 people in a span of a probably a year and a half. Something that usually would cost us thousands of dollars. I dunno how much money I spend, probably just 300,000 to do everything. Can you imagine? I mean, that's significantly cheap compared to any other quote that I've been getting from an academic center. So, I sometimes go for the crazy idea, right? Like, what's the craziest thing that I could think of? I literally, I write it down, right? And then I just try to double check with my lawyer. "Am I doing something illegal here?" And I, yeah, I cross reference with other founders. " I'm thinking of doing this, how that's that sound?" And they're like, "This is pretty non-traditional, Maria, but I mean, if you can get it done..." I'm like, "Yeah, of course I can get it done." And I just get it done. I just don't take a no for an answer. I'm very good at also finding, convincing people to jump on board with the vision, the mission. This excitement, this energy, people really get very engaged with Samay and with me as a founder, and they love it. Most of these people either have invested in the company, they are helping me many more hours, pro bono, literally free, and we are building together. [00:27:43] Lindsey Dinneen: Wow, that is so cool. And what a fantastic story. Thank you for sharing that one as well. Oh my word. [00:27:50] Maria Artunduaga: I have way too many stories to share. This is the one I really like to, to tell people. [00:27:55] Lindsey Dinneen: I love that, and I love the willingness to come up with those crazy ideas. And it might be just so crazy that it works. So, hey, you never know until you try, and that's fantastic. Oh my gosh, I love that approach. Alright, so pivoting the conversation a little bit just for fun. Imagine you are to be offered a million dollars to teach a masterclass... I know! ...to teach a masterclass on anything you want. What would you choose to teach? [00:28:22] Maria Artunduaga: Yeah. So, good question. So, gosh, I, I tackle problem. So my, my brain again is very good at figuring stuff out. That plus the fact that I'm very stubborn. So if I'm into something, I don't give up easily. And now I'm gonna tell the story about our winning MedTech Innovator. We beat 65 companies globally, right? And I still like, sort of, I cannot process that we won. So the story goes like this, but a year ago, I tried to raise five millions, my very first institutional round, and I totally flopped. [00:28:55] Lindsey Dinneen: Oh. [00:28:56] Maria Artunduaga: I only got $200,000 because multiple funds that I was talking to, they wanted me to feel half of the round before weighing any money or signing anything. So you can imagine. So do I got, you know, chicken or the egg problem? I failed. And instead of crying or mopping, I thought, "Okay, wait. I got into Medtech Innovator. You know what? I'm just gonna win that competition, still $350,000." And why not? So obviously people, my advisors, my best friend, "Like, you're crazy. It's the most competitive thing ever. You're not established in the field. People know who you are, but it's not like you have exited a company or anything, right? You're not even an engineer, Maria." So what I did was, again I went back to my whiteboard. Again, I probably should have become an engineer before, I dunno. I'm really good at solving problems. So I was like, "You know, this is a problem. These are the different ways how I can tackle this." And more importantly, I'm very good at the studying stuff. I really like, again, knowing, wisdom, information. I just love that. I really love that. So what I did was, I treat it like a big project, and I talked to the past winners, anyone who had done or won any sort of like prize with MedTech Innovator, and I figure out their secret sauce. So I either talk to them, I studied every single video, every single pitch. I spend many hours studying everyone who had one or had done significantly well throughout the accelerator. So what I discovered was the accelerator was kind of a school, like a school. So the harder you work, the better you do. And one of the things that I realized was that mentors and reviewers were key players. So I focused on building those connections. I met with many of them. I probably spent about, I don't know, probably four to five hours meeting with mentors, anyone who I thought could help me somehow, obviously, for free, because a lot of the help that they give used for free. And I also spent a lot of time doing homework, the webinars, et cetera, et cetera. I ask a lot of people for advice. I really got people excited about Samay. I recruited my mentors and they got on board from day one. Because of that, I started building those relationships and it was authentic. I mean, don't get me wrong, this wasn't like, you know, I'm trying to play anybody. I really care about what they had to say, and I incorporate all that feedback into my company to this day. So the other thing is, I make sure to go to everywhere, every webinar, every event, everything. My camera was always on, because most people, when they do their webinars, they don't even turn on their cameras, right? So I was very engaged. I was asking questions, I was getting involved with everything. Same thing with the Slack channel that we have for MedTech Innovator. I was helping people, I was sharing stuff. I was even offering to make introductions. I really made sure that people knew who I was. And I obviously also asked the MedTech Innovator people, the staff, for help, feedback, right? Am I doing this right? What do you think I should do? Anything that you can share with me that you think. I was very clear with them. I wanna go to the, I wanna get to the finals. I told them, and I remember they telling me, "Oh, Maria, about getting to the finals, it's so hard. It depends on the strategics and the sponsors." And I was like, " I'm gonna get there. What do you think I should do?" So I literally ask a lot of people how I needed to get there. And with the finals, the way how they pick the finalist, it's actually the mentors who go in front of the strategics, and they sort of champion your company. And they really went to bat for us. They told them how committed I was, the many people that from my team were actually going for participating to the winner because I brought people from my team... [00:32:45] Lindsey Dinneen: Yeah. [00:32:46] Maria Artunduaga: You know, very few founders did that. I brought people from Colombia, obviously online, people who barely could understand English. But, I made them prepare questions. "You need to do this and that we need to be super engaged. We need to help other people." And they saw it was hard work. And at the end, we got into the finals and what I realized was, okay, so after the finals, I understood that the game was, obviously it changed. The way how the winner is chosen is that the audience votes, right, during The MedTech Conference. So what I did was, I went all in on social media. We made an awesome video for the best video competition. I remember that that was the first thing that I did back in June. I scheduled two weeks. I flew to Columbia. I hired right people. I made sure that I was perfect, so I was part of the creative team. I designed everything. Again, I really like arts, right? That's why, one of the reasons why I didn't, I was in pleasantry and that's why I really like dancing too, right? So I'm obsessive with everything that we do. I really am into the details and I supervise everything. And we also got into the finals for the best video competition. So I was going to this problem from every single angle. I didn't let anything up to chance. I, yeah, I'm a freak. I'm a control freak. That's what I did. I remember that even for the pitch, the four and a half minute pitch, I practiced, I don't know how many hours, but every single thing that I say that was obviously memorized, needed to be perfect. The way how I, let's go back to dancing since you're a dancer yourself, the way how I moved my hands, right? The way, how I walked on that stage, everything was rehearsed. So, yeah, I mean, I just I worked my ass off. I mean, everything was the way it needed to be and that's how we won. [00:34:39] Lindsey Dinneen: Yeah. Wow. That's great. What a fantastic story. Yeah. Amazing. Yes. I love how it's so choreographed. Yeah, that's [00:34:48] Maria Artunduaga: great. It was choreographed, [00:34:50] Lindsey Dinneen: I love that. Excellent. Well, I know you have touched on the importance of legacy and how much that means to you, but how do you wish to be remembered after you leave this world? [00:35:03] Maria Artunduaga: Oh gosh. Yeah. I mean, so I have a little daughter, I want to some somehow replicate the same experience that I had with my mom. Maybe she doesn't even realize how much of the inspiration and the impact that she had on me. And again, leading by example, I don't spend a lot of hours with my daughter, right? I have a nanny for 12 hours. So my salary goes to her payment, right? Yeah, I wanna be remembered as somebody who tried very hard, who literally, instead of saying things, I walked the talk. The things that I said I was going to say. For example, I'm very opinionated with anything diversity and inclusion because, as I've said, I've experienced discrimination myself. So I walk the talk, I build a product, I build the change. I worked really hard. I impacted a lot of people. And more importantly, the world has changed somehow because I existed. So that's that. It's as simple as that. I wanna help other people get to fulfillment of their lives and their dreams. And yeah, and I obviously wanna be happy while I do all of these things. And more importantly, I wanna feel that I learned a lot. I really like learning. The process of learning every single day, learning a new thing makes me super happy. So if I don't learn something new, I consider day as, you know, as like a flop or something. So yeah, it's very simple. I'm actually a very simple person, I'm not that complicated. [00:36:30] Lindsey Dinneen: Yeah. Okay. And then final question. What is one thing that makes you smile every time you see or think about it? [00:36:39] Maria Artunduaga: Oh, cute. I mean, obviously my daughter. So I'm a mom. I'm 44, well, almost 45, and I had her at 42. So just thinking about her makes me smile every single time. She's a miracle baby. She's, you know, after four years of IVF, eight retrievals, it finally happened. I finally had her, and having her in my life has turned my world upside down in the best way. She's determined, and she's only three. She's diving into doing all sorts of things. She's doing gymnastics, she's building Legos, she's doing engineering stuff. I really like that "I can do anything attitude" and obviously I'm sort of like reinforcing her to do anything she wants to try. So seeing her try all these new things, all this confidence that I, that she has. It's like, I don't know. I mean, that inspires me. That motivates me to be a better mom, a better CEO, and to do exactly the same thing with the people that I work with. So everyone in my company, I I tell them I'm a mom, right? So, remember that, and I try to do the same with them. It's like I tell them, what do you wanna do? What do you wanna learn this month? What do you need? Right? My work as a CEO is getting the resources and put out the fires. Just tell me, and this is your playground, so I'm trying to do exactly the same with my daughter too. But yeah, I'm very happy with her. [00:38:07] Lindsey Dinneen: Aw, that's wonderful. I'm so glad. Well, oh my goodness, this conversation has been amazing. I kind of wish it didn't have to end, but I also wanna respect your time 'cause obviously you have so much going on. But thank you so much for sharing about your story, your advice. You're so inspiring, and I know this is gonna inspire so many people to go for it, and not to have the fear, to have that problem solving mentality, and growth mindset and learning and, hey, look where curiosity got you. [00:38:37] Maria Artunduaga: Yeah, exactly. That's a perfect slogan. It's all about that curiosity and it gets you places. Look at me. [00:38:43] Lindsey Dinneen: Yeah, exactly. Yeah. And this is just the start. [00:38:47] Maria Artunduaga: Yes, of course. [00:38:48] Lindsey Dinneen: Indeed. So I just wanna say thank you again for your time today, and we just wish you the most continued success as you work to change lives for a better world. [00:38:58] Maria Artunduaga: Thank you so much and thank you again for invitation. I really enjoyed it. [00:39:02] Lindsey Dinneen: Yeah, absolutely. Me too. And we are honored to be making a donation on your behalf as a thank you for your time today to the American Society for the Prevention of Cruelty to Animals, which is dedicated to preventing animal cruelty in the United States. We really appreciate you choosing that organization to support and thank you just again, so very much for your time here today. Yeah, and holy cannoli, thank you so much to our listeners for tuning in, and if you're feeling as inspired as I am right now, I'd love it if you'd share this episode with a colleague or two, and we'll catch you next time. [00:39:44] Ben Trombold: The Leading Difference is brought to you by Velentium. Velentium is a full-service CDMO with 100% in-house capability to design, develop, and manufacture medical devices from class two wearables to class three active implantable medical devices. Velentium specializes in active implantables, leads, programmers, and accessories across a wide range of indications, such as neuromodulation, deep brain stimulation, cardiac management, and diabetes management. Velentium's core competencies include electrical, firmware, and mechanical design, mobile apps, embedded cybersecurity, human factors and usability, automated test systems, systems engineering, and contract manufacturing. Velentium works with clients worldwide, from startups seeking funding to established Fortune 100 companies. Visit velentium.com to explore your next step in medical device development.
First up on the podcast, Staff Writer Erik Stokstad talks with host Sarah Crespi about how scientists are probing the world's hottest forests to better understand how plants will cope with climate change. His story is part of a special issue on plants and heat, which includes reviews and perspectives on the fate of plants in a warming world. Next on the show, “convergent” antibodies may underlie the growing number of people allergic to peanuts. Sarita Patil, co-director of the Food Allergy Center at Massachusetts General Hospital and assistant professor at Harvard Medical School, joins the podcast to discuss her research on allergies and antibodies. She explains how different people appear to create antibodies with similar gene sequences and 3D structures that react to peanut proteins—a big surprise given the importance of randomness in the immune system's ability to recognize harmful invaders. This week's episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi; Erik Stokstad Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome to Real Food Recovery, a podcast created by two lifelong processed food addicts with over 100 years of addiction (and recovery) between them. Paige Alexander and Jamie Morgan Reno use their Real Food Recovery podcast and social media channels to share their struggles, lessons learned, tools, tips, and resources that freed them from decades of food addiction, obsession, and loss. Dr. Roberto Olivardia is a Clinical Psychologist, Lecturer in Psychology in the Department of Psychiatry at Harvard Medical School and Clinical Associate at McLean Hospital. He maintains a private psychotherapy practice in Lexington, Massachusetts, where he specializes in the treatment of Attention Deficit Hyperactivity Disorder (ADHD), Obsessive-Compulsive Disorder (OCD), and Body Dysmorphic Disorder (BDD), as well as issues that face students with learning disabilities. He is a nationally recognized expert in eating disorders and body image problems in boys and men. He is co-author of The Adonis Complex, the first book of its kind detailing male body image issues. He has appeared in publications such as TIME, GQ, and Rolling Stone, and has been featured on Good Morning America, CNN, and VH1. You can find more about Dr. Olivardia here: https://www.mcleanhospital.org/profile/roberto-olivardia In every Real Food Recovery episode, Paige and Jamie take time to answer viewer questions about processed food addiction, obsession, and recovery, be sure to submit yours on their YouTube Channel or Facebook Page. You can also follow Real Food Recovery on Instagram (@realfoodrecovery4u), TikTok (@realfoodrecovery) or at www.realfoodrecovery4u.com.
First up on the podcast, Staff Writer Erik Stokstad talks with host Sarah Crespi about how scientists are probing the world's hottest forests to better understand how plants will cope with climate change. His story is part of a special issue on plants and heat, which includes reviews and perspectives on the fate of plants in a warming world. Next on the show, “convergent” antibodies may underlie the growing number of people allergic to peanuts. Sarita Patil, co-director of the Food Allergy Center at Massachusetts General Hospital and assistant professor at Harvard Medical School, joins the podcast to discuss her research on allergies and antibodies. She explains how different people appear to create antibodies with similar gene sequences and 3D structures that react to peanut proteins—a big surprise given the importance of randomness in the immune system's ability to recognize harmful invaders. This week's episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi; Erik Stokstad Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. David Kessler is a renowned pediatrician, lawyer, public health advocate, and former Commissioner of the U.S. Food and Drug Administration (FDA). A graduate of Amherst College, the University of Chicago Law School, and Harvard Medical School, Dr. Kessler has spent his career at the intersection of science, policy, and consumer protection. He served as Dean of the Yale School of Medicine and the University of California, San Francisco Medical School, and most recently held the role of Chief Science Officer for the White House COVID-19 Response Team. Dr. Kessler is the acclaimed author of several influential books including the New York Times bestseller The End of Overeating, Fast Carbs, Slow Carbs, and his latest work, Diet, Drugs & Dopamine: The New Science on Achieving a Healthy Weight. His writing and research have been pivotal in shifting the public health conversation from willpower to biological understanding—especially regarding food addiction, the manipulation of hyper-palatable foods, and the role of dopamine in modern eating behaviors. A true trailblazer in the field, Dr. Kessler has dedicated decades to unraveling the powerful science behind why we eat the way we do—and how we can reclaim our health in a world of ultra-processed foods. Dr. Kessler shares his personal journey with weight regain and the "aha moment" that led him to call it what it is—addiction. He explores the role of GLP-1 medications, the dark side of food addiction, and how we must move beyond willpower to tackle this epidemic with compassion, science, and actionable tools.
Dr. Comen has dedicated her medical career to saving the lives of women. An award-winning, internationally sought-after clinician and physician-scientist, Dr. Comen works as a medical oncologist with a specialty in breast cancer at Memorial Sloan Kettering Cancer Center and is an assistant professor of medicine at Weill Cornell Medical College. She earned her BA in the history of science from Harvard College and her MD from Harvard Medical School, then completed her residency in Internal Medicine at Mount Sinai Hospital and her fellowship in oncology at Memorial Sloan Kettering Cancer Center. She's the author of All In Her Head: The Truth and Lies Early Medicine Taught Us About Women's Bodies and Why It Matters Today which we discuss on the show today. Join The Newsletter + Receive Your Free List of 52 Selfcare Tips Connect with Michele on Instagram RESOURCES MENTIONED Website: https://www.drelizabethcomen.com/ Instagram: https://www.instagram.com/drelizabethcomen/ Book: All In Her Head: The Truth and Lies Early Medicine Taught Us About Women's Bodies and Why It Matters Today If you enjoyed this interview, please take a moment to rate and review it on Apple podcasts. Your reviews are so appreciated! Not sure how to do it? Instructions are below. XO, Michele Rate + Review: 1. Click on this link 2. Click “View in Apple Podcasts” button 3. Make sure to “Follow” 4. Scroll down until you see “Ratings and Reviews” as shown below.
June 10, 2025 | In this bonus episode of The Chain, Daniel Chen, MD, PhD, founder and CEO of Synthetic Design Lab, returns for the Science Commune segment and speaks with Keith Flaherty, MD, FAACR, professor of Medicine of Harvard Medical School and president-elect of AACR. They discuss Flaherty's prolific career; how his background led him to pursue a career in medicine; how public and private sectors are coming together in oncology around collaborations; reflections on targeted therapies and technologies; optimism around how AI will impact society and the future of medicine positively; and how we need to detect and treat disease early. Links from this episode: PEGS Boston Conference & Expo Engineering Bispecific Antibodies Synthetic Design Lab Harvard Medical School AACR
If you've ever avoided talking about death with a loved one because it felt too uncomfortable or culturally off-limits, episode 344 is for you. Dr. Cynthia X. Pan, a leading expert in end-of-life care, shares practical strategies for navigating these sensitive conversations with empathy and clarity. Learn how to approach topics like advanced directives and final wishes—especially across cultural lines—so you can honor your loved ones' values and find peace in knowing you did right by them.In This Episode, You Will Learn:(1:25) The evolution of palliative care(2:55) Ethics and cultural diversity in end-of-life conversations(4:30) Reframing death with dignity and celebration(5:51) The power of showing up(6:47) Family dynamics and grief during COVID(10:05) Why advanced directives matter(14:30) When systems ignore patient wishes(15:44) Navigating cultural resistance to end-of-life talk(21:56) Breaking death taboos and redefining goodbyeIn today's episode, I'm joined by Dr. Cynthia X. Pan, a board-certified physician in internal medicine, geriatrics, and hospice and palliative medicine. She holds a BA in Biology from Harvard and an MD from Stony Brook University School of Medicine. Dr. Pan completed her internal medicine residency at the University of Rochester and a geriatrics fellowship at Harvard Medical School's Division on Aging. She now serves as Chief of Geriatrics and Palliative Care Medicine and Designated Institutional Official for Graduate Medical Education at NewYork-Presbyterian Queens. A Professor at Weill Cornell Medical College, she educates future healthcare providers on palliative care, cultural humility, and communication. Fluent in Mandarin and Spanish, she brings a multicultural lens to patient-centered care.Throughout this episode, Dr. Pan uses her medical background and personal experiences to share both clinical insight and emotional depth. She reflects on working in one of the most culturally diverse regions in the U.S., where sensitive end-of-life conversations require compassion and cultural awareness. Through stories of caring for her father and mother-in-law, she highlights the importance of honoring patients' wishes. She also discusses how to approach taboo topics like death with respect and indirect communication—especially in communities where such discussions are avoided. Her guidance helps us embrace these moments with courage, clarity, and connection.Connect with Dr. Cynthia X. Pan:WebsiteInstagramLinkedInBook: Exit Strategies: Living Lessons from Dying People Let's Connect:WebsiteLinkedInFacebookInstagramTwitterThe Grief and Happiness Alliance Hosted on Acast. See acast.com/privacy for more information.
If you're tired of picking apart your appearance, hiding your body, or never feeling good enough, this episode is for you. Today, you'll learn the 4 simple steps you can take to build lasting confidence and finally feel good in your body. This powerful episode was inspired by a raw and emotional conversation Mel had with viral comedian Jake Shane. When Jake admitted he hates how he looks and struggles with self-worth, it opened the door to a bigger truth: millions of people feel the exact same way—but don't know what to do about it. So, Mel called in the experts. In this episode, you'll hear from Mel and Jake and learn tools from two renowned psychiatrists: -Dr. Judith Joseph, MD, double board-certified psychiatrist, professor at Columbia and NYU Medical Schools, and author of the bestselling book High Functioning. -Dr. Ashwini Nadkarni, MD, Harvard Medical School professor and psychiatrist at Mass General Brigham who specializes in anxiety, OCD, PTSD, and depression. Together, they break down the surprising psychology behind body shame and give you a practical, proven roadmap to feeling better, starting now. You'll learn how to: Break free from body shame, obsession, and constant comparisonRewire your brain for confidence and lasting self-acceptanceUse 4 science-backed steps to heal how you see yourselfUnderstand the hidden psychology behind body image and self-talkUnpack the shocking research on how screens and modern life are distorting your self-image (and how to fix it)This isn't just a conversation. It's your roadmap to healing, backed by science. After listening you will have the tools, the science, and the mindset shift you need to stop hiding—and start seeing yourself clearly. Because when you change how you see yourself, you change everything. For more resources, click here for the podcast episode page. If you liked this episode, you'll love listening to this one next: How to Build Real Confidence: 7 Truths to Unlock Your Authentic SelfConnect with Mel: Get Mel's #1 bestselling book, The Let Them TheoryWatch the episodes on YouTubeFollow Mel on Instagram The Mel Robbins Podcast InstagramMel's TikTok Sign up for Mel's personal letter Subscribe to SiriusXM Podcasts+ to listen to new episodes ad-freeDisclaimer
Do you feel like your inner critic is trying to make you hate yourself? That deep-rooted feeling that you're not good enough can quietly shape your life, but it doesn't have to stay that way. I'm joined by Dr. Blaise Aguirre, professor of psychiatry at Harvard Medical School and one of the top experts on self-hatred and borderline personality disorder. With decades of experience, he's here to unravel why self-hatred develops and what you can do to overcome it. Some of the things we discuss are: Why self-hatred is a learned behavior (and how to identify its roots). The hidden ways self-hatred creeps into your life, like perfectionism and people-pleasing. How to tell the difference between low self-esteem and self-hatred. Simple steps that can help you stop hating yourself and build self-compassion. Why small acts of kindness can help you see your value more clearly. The exact steps you can take to stop hating yourself today. Want more tips for building mental strength? Subscribe to Mentally Stronger Premium and get weekly AMA episodes and monthly bonuses to help you grow mentally stronger! Links & Resources Ihatemyselfbook.com Follow Dr. Aguirre on Instagram — @blaiseaguirre Connect with the Show Buy Amy's books on mental strength Connect with Amy on Instagram — @AmyMorinAuthor AmyMorinLCSW.com Sponsors Quince — Get free shipping and 365-day returns at Quince.com/stronger OneSkin — Get 15% off OneSkin with the code STRONGER at https://www.oneskin.co/ #oneskinpod Calm — Get 40% off a Calm Premium Subscription at calm.com/STRONGER AirDoctor — Head to AirDoctorPro.com and use promo code STRONGER to get UP TO $300 off today! Shopify — Sign up for your one-dollar-per-month trial period at Shopify.com/mentallystronger ZocDoc — Go to Zocdoc.com/STRONGER to find and instantly book a top-rated doctor today! Mentally Strong — Sign up for your free 7-day trial at MentallyStrong.Downpait.Ai Learn more about your ad choices. Visit megaphone.fm/adchoices
Today, Dr. Kat speaks with Dr. Lee Cohen about his powerful new documentary, More Than Blue. Dr. Cohen shares the inspiration behind the film, how it was made, and his hopes for its impact in destigmatizing perinatal mental health conditions. A passionate advocate, Dr. Cohen offers insights from his decades of work helping women navigate mood and anxiety disorders during and after pregnancy. Please check out the trailer for More Than Blue here: https://womensmentalhealth.org/more-than-blue-documentary/ Bio Dr. Cohen: Dr. Lee Cohen is Director of the Ammon-Pinizzotto Center for Women's Mental Health at Massachusetts General Hospital and Professor of Psychiatry at Harvard Medical School. A pioneer in perinatal and reproductive psychiatry, Dr. Cohen has dedicated his career to research, clinical care, and education focused on mental health across the female reproductive lifespan. He has authored over 350 publications in journals including JAMA and the American Journal of Psychiatry, and has received multiple awards for his contributions to maternal mental health. Dr. Cohen is a nationally recognized leader and a passionate voice in improving care for women with perinatal mood and anxiety disorders. Show Highlights: Dr. Cohen's journey in women's mental health The key is getting patients well during pregnancy. Today's trends in perinatal mental health, from Dr. Cohen's perspective as a researcher and clinician Increasing awareness also increases access to care for at-risk patients. Accessing care doesn't always result in “well” patients several months later. Planning process for the “More Than Blue” documentary Characteristics of patients with PMADs Process of collecting, curating, and organizing diverse stories via womensmentalhealth.org to destigmatize treatment options and show multiple perspectives Dr. Cohen's perspective on the importance of including postpartum psychosis in the documentary (A YouTube video is in the works.) Dr. Cohen's passion and optimism for his work: “We're not done.” The intentional plan for screenings and dissemination of “More Than Blue” “Lowering the burden” in helping people feel comfortable in telling their stories to optimize the likelihood of proper care Resources: Connect with Dr. Cohen: The Center for Women's Mental Health at MGH, Facebook, Instagram, and X. Womensmentalhealth.org Call the National Maternal Mental Health Hotline at 1-833-TLC-MAMA or visit cdph.ca.gov Please find resources in English and Spanish at Postpartum Support International, or contact us by phone or text at 1-800-944-4773. There are many free resources available, including online support groups, peer mentors, a specialist provider directory, and perinatal mental health training for therapists, physicians, nurses, doulas, and anyone who wants to become more supportive in offering services. You can also follow PSI on social media, including Instagram, Facebook, and other platforms. Visit www.postpartum.net/professionals/certificate-trainings/ for information on the grief course. Visit my website at www.wellmindperinatal.com for more information, resources, and courses you can take today!If you are a California resident seeking a therapist in perinatal mental health, please email me about openings for private pay clients. Learn more about your ad choices. Visit podcastchoices.com/adchoices
In today's episode, we sat down for part 2 of our discussion with Elizabeth Mittendorf, MD, PhD, MHCM, the 2026-2027 president-elect of the American Society of Clinical Oncology (ASCO). Dr Mittendorf holds numerous leadership roles, including the Robert and Karen Hale Distinguished Chair in Surgical Oncology and vice chair for research in the Department of Surgery at Brigham and Women's Hospital; co-leader of the Breast Program and director of the Breast Immuno-Oncology Program at the Dana-Farber Brigham Cancer Center; co-leader of the Parker Institute for Cancer Immunotherapy at the Dana-Farber Cancer Institute; and a professor of surgery at Harvard Medical School, all in Boston, Massachusetts. In this discussion, Dr Mittendorf shared how ASCO is strategically preparing to address the long-term implications of proposed federal research funding cuts. She emphasized the significant return on investment generated by sustained NIH support, underscoring its role in fostering scientific innovation and stimulating the broader economy. She also advocated for structural reforms to be developed collaboratively with researchers, institutions, and policymakers to ensure continued progress in oncology is maintained, particularly in underfunded areas, such as prevention research. Dr Mittendorf also previewed her broader vision for ASCO, including expanding global collaboration and advancing equitable access to cancer care. She noted that these efforts will be complemented by continued emphasis on multidisciplinary care delivery and mentorship, which she discussed in more detail in part one of our conversation.
Amar Kelkar is a physician at the Dana-Farber Cancer Institute and an instructor in medicine at Harvard Medical School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A.H. Kelkar. U.S. Research Leadership at a Crossroads — The Impact of Reducing NIH Indirect-Cost Coverage. N Engl J Med 2025;392:2081-2084.
Elevated levels of lipoprotein(a) are associated with higher rates of cardiovascular events. Author Samia Mora, MD, MHS, of Brigham and Women's Hospital and Harvard Medical School discusses measurement and interpretation of lipoprotein (a) levels with JAMA Deputy Editor Mary McGrae McDermott, MD. Related Content: Lipoprotein(a)
In this episode, we dive deep into the science of aging with longevity expert Dr. David Barzilai. You've probably seen people online claiming to have reversed their biological age—but is any of that actually possible? We unpack the truth behind biological age tests, anti-aging supplements, and the wildest longevity trends (yes, even blood transfusions from your kids). Dr. Barzilai explains what really works—spoiler: it's not $2 million worth of pills—and shares simple, science-backed ways to live healthier for longer. If you want to cut through the hype and get real about living better, this episode is a must-listen.About Dr. Barzilai: Dr. David Barzilai is a physician and the CEO of Healthspan Coaching LLC. He is a founding faculty member and Trustee at the Geneva College of Longevity Science, and serves as a lecturer at Harvard Medical School. Board-certified in lifestyle medicine, Dr. Barzilai holds both an MD and a PhD in health services research.Find him on X here or connect with him here. Sign up for our newsletter here!For weekly episodes, come join the Foodie Fam!Check out our book!Chat with us on IG @foodweneedtotalk!Be friends with Juna on Instagram and Tiktok! Learn about your ad choices: dovetail.prx.org/ad-choices
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Webinar from the National Celiac Assocaition: Gut-Brain Health and Celiac Disease: Caring for Your Second “Brain"Jun 6, 2025 01:00 PM in Eastern TimeJoin the National Celiac Association for their Spring 2025 webinar in the “From the Experts” series. Speakers will present on selected topics for 60 minutes, followed by 15 minutes for Q&A, on Friday, June 6, 2025 from 1-2:15 pm ET.Dr Alessio Fasano, MD, Director of the Mucosal Immunology and Biology Research Center at Mass General for Children; Professor of Pediatrics at Harvard Medical School; and Professor of Nutrition at T.H. Chan School of Public Health, will speak about the “crosstalk” between the gut microbiome and the brain, focusing on developmental disorders and mental health issues in the context of gluten-related disorders. Deanna Kelly, PharmD, BCPP, the Dr. William and Carol Carpenter Professor in Psychiatry for Mental Illness at the University of Maryland School of Medicine and Director and Chief of the Treatment Research Program at the Maryland Psychiatric Research Center, will share her research on schizophrenia, anxiety, and depression, which are often diagnosed as part of the impressive range of celiac disease symptoms.Register here: https://partners.zoom.us/webinar/register/WN_NtbsSjn7TqCVOEUxY2t_cQ?mc_cid=6f22c46ae9#/registrationI would love to hear from you! Leave your messages for Andrea at contact@baltimoreglutenfree.com and check out www.baltimoreglutenfree.comInstagramFacebookGluten Free College 101Website: www.glutenfreecollege.comFacebook: http://www.Facebook.com/Glutenfreecollege Hosted on Acast. See acast.com/privacy for more information.
In today's episode, we had the pleasure of speaking with Elizabeth Mittendorf, MD, PhD, MHCM, the 2026 president-elect of ASCO. Dr Mittendorf is the Robert and Karen Hale Distinguished Chair in Surgical Oncology and the vice chair for research in the Department of Surgery at the Brigham and Women's Hospital; co-leader of the Breast Program and director of the Breast Immuno-Oncology Program at the Dana-Farber Brigham Cancer Center; co-leader of the Parker Institute for Cancer Immunotherapy at the Dana-Farber Cancer Institute; and a professor of surgery at Harvard Medical School, all in Boston, Massachusetts. In our exclusive interview, Dr Mittendorf discussed her priorities for advancing oncology practice and improving patient outcomes during her presidency. These include multidisciplinary cancer care, workforce well-being, leveraging artificial intelligence to enhance efficiency, and addressing global cancer care. She also emphasized the importance of mentorship and sponsorship for early career professionals, highlighting her personal experience with multiple mentors and her commitment to supporting the next generation of oncology professionals.
Dr. John Sweetenham shares highlights from Day 4 of the 2025 ASCO Annual Meeting, including new research on maintenance therapy in small cell lung cancer and a virtual reality psychosocial intervention for patients undergoing hematopoietic stem cell transplantation. Transcript Hello, I'm Dr. John Sweetenham, the host of the ASCO Daily News Podcast, with my takeaways on selected abstracts from Day 4 of the 2025 ASCO Annual Meeting. My disclosures are available in the transcript of this episode. Today's selection features reports of 3 randomized trials in very different clinical settings: maintenance therapy in extensive small cell lung cancer (SCLC), upfront surgery in advanced ovarian cancer, and a supportive care intervention for patients undergoing hematopoietic stem cell transplantation. The first of these studies, Abstract 8006, was presented by Dr. Luis Paz-Ares from the University Hospital [October 12] in Madrid, Spain, and reports the primary results of the IMforte trial. This was a phase 3 trial evaluating the combination of lurbinectedin and atezolizumab as first-line maintenance therapy in patients with extensive small cell lung cancer. Despite some improvements in the first-line treatment of extensive small cell lung cancer with the use of checkpoint inhibitors in combination with platinum-based chemotherapy, most of the patients experience early disease progression and long-term survival remains very limited. This provides a rationale for considering a maintenance intervention. Lurbinectedin is an alkylating agent and transcription inhibitor [that is] already approved in the United States for patients with relapsed/refractory metastatic SCLC following platinum-based chemotherapy. It has been shown to synergize with immune checkpoint inhibitors in pre-clinical studies and has also been evaluated in early-phase clinical trials. The IMforte trial is a global, randomized trial in which patients are initially treated with atezolizumab, and those patients who do not progress on induction therapy are then randomized to maintenance therapy with atezolizumab alone or atezolizumab with lurbinectedin. The primary endpoints of the study were progression-free and overall survival. Four hundred and eighty-three patients were randomized and at a median follow-up of 15 months, the median progression-free survival for patients who received the combination was 5.4 months and the median overall survival was 13.2 months. This compares with 2.1 and 10.6 months, respectively, in patients who received atezolizumab only. The lurbinectedin and atezolizumab combination was generally well-tolerated, with no new or unexpected safety signals. The benefit was consistent in magnitude across all the relevant patient subgroups. This is the first phase 3 study to show a progression-free and overall survivial improvement with first-line maintenance in extensive stage SCLC and the result is likely to be practice-changing, establishing a new standard of care in this tough-to-treat disease. Next up is LBA5500, presented by Dr. Sven Mahner from LMU University in Munich, Germany. This describes the results of the TRUST study, a randomized trial of upfront surgical therapy in advanced ovarian cancer. As background, total macroscopic tumor resection with maximal effort cytoreductive surgery is the cornerstone of treatment in patients with advanced ovarian cancer. The optimal timing of such surgery remains controversial, whether it's more beneficial as a primary cytoreductive surgery before chemotherapy or in the form of interval cytoreductive surgery after 3 cycles of neoadjuvant chemotherapy. Previous studies have addressed this issue, but results have been confounded by issues of patient and center selection. The TRUST study is a randomized, international, multicenter phase 3 trial that compares the outcomes of the timing of surgery in surgically fit patients with seemingly resectable FIGO stage IIIB/IVB ovarian, tubal, and peritoneal carcinoma. To ensure consistent and adequate surgical quality, participating centers in the trial were required to obtain accreditation and undergo an onsite quality assurance review. This included assessment of infrastructure, surgical proficiency, complete resection rates, and surgical volume. Seven hundred and ninety-seven patients with advanced ovarian cancer were randomized to undergo surgery prior to therapy with 6 cycles of carboplatin and paclitaxel along with bevacizumab and a PARP inhibitor, or to have the surgery between the third and fourth cycle of the same systemic therapy. Of the initial 797 patients, 688 comprised the intent-to-treat population, of whom 345 received primary cytoreductive surgery and 343 received neoadjuvant chemotherapy followed by interval cytoreductive surgery. The results show that patients undergoing primary surgery had significantly improved progression-free survival compared with those who had interval cytoreductive surgery (median progression-free survival was 22.1 months versus 19.7 months). No difference in overall survival was observed between the 2 arms of the study. This is the first study to show a benefit for primary cytoreductive surgery, although the progression-free survival improvement was not reflected in an overall survival difference. A subgroup analysis for patients who underwent complete cytoreduction suggests a progression-free survival and survival benefit, although it isn't clear to me that the study was powered for this endpoint. Nevertheless, these are very difficult studies to perform, and the investigators should be congratulated for this robustly conducted clinical trial. Today's final abstract is 1504, presented by Dr. Hermioni Amonoo from Harvard Medical School. The trial evaluated BMT-VR, a virtual reality psychosocial intervention for patients undergoing bone marrow transplantation. This randomized trial included adult patients undergoing autologous and allogeneic transplantation. The BMT-VR platform included, among others, modules addressing psychoeducation, coping, acceptance, and gratitude. BMT-VR patients were provided with VR headsets and completed all modules during their hospitalization. Patient-reported outcomes were then assessed at 2, 4, 12, and 24 weeks post-BMT. Use of the VR tool was tracked during hospitalization. Control patients received usual care during their hospital stay and were then assessed at the same intervals post-BMT. Eighty evaluable patients were randomized, 39 to BMT-VR and 41 to usual care. Completion rates for the BMT-VR modules were high [at] around 70-75%. Patients who received the BMT-VR intervention experienced significantly improved anxiety, quality of life, and coping at 4 weeks post-BMT. In the longer term, sustained benefits were seen at 24 weeks for some endpoints including quality of life, with some benefits, including for depression and PTSD symptoms, improving longitudinally over the study period. These data are preliminary and will need to be confirmed in larger multicenter studies, but this trial demonstrates the feasibility of using virtual interventions in our patients and also provides intriguing preliminary data that they may be effective. Thanks for listening to today's report and I hope you will join me again tomorrow to hear more top takeaways from the final day of ASCO25. If you value the insights that you hear on the ASCO Daily News Podcast, please remember to rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Find out more about today's speaker: Dr. John Sweetenham Follow ASCO on social media: @ASCO on Twitter @ASCO on Bluesky ASCO on Facebook ASCO on LinkedIn Disclosures: Dr. John Sweetenham: No relationships to disclose
Often, those who suffer from anxiety either exhaust themselves trying to cure it or they resign themselves to a lifetime of fear and worry. But according to Dr. David Rosmarin, instead of fighting anxiety, we can learn to turn it into a strength. He discusses how we can use anxiety as a tool to be more self-aware, self-accepting, and resilient. Dr. Rosmarin is the founder of the Center for Anxiety, an associate professor at Harvard Medical School, and director of the McLean Hospital Spirituality and Mental Health Program. He is a clinical innovator in the treatment of anxiety, a board-certified clinical psychologist, and a peer-reviewed scholar. He is the author of the book, Thriving with Anxiety: 9 Tools to Make Your Anxiety Work for You.
00:00:00 - Discussion about AI Songs and Naked Man in Shed The episode opens with technical hiccups and updates on new AI song packs created by the hosts. They discuss a bizarre news story about a naked man found in a Lowe's display shed with Vaseline and a telephone, inspiring a new AI song called "Don't Look in the Shed." 00:10:00 - Alex Jones Clips and Jeremy Renner Teaser Debut of the AI song “Don't Look in the Shed,” filled with humorous and grunge-inspired lyrics. A roundup of Alex Jones' wildest clips of the week. A Steven Seagal-style preview introduces upcoming topics: Jeremy Renner's near-death experience, DMT entities, haunted dolls, Ohio marijuana legislation, AI homework tools, and alien spheres. 00:20:00 - Jeremy Renner's Spiritual Awakening Renner shares how his near-death accident changed his view on life, describing a peaceful, out-of-body experience. Emphasis on spiritual growth and valuing love over material things. Conversation shifts toward DMT as a possible bridge to the afterlife. 00:30:00 - Guide to DMT Entities Breakdown of various DMT entities reported by users: machine elves, clowns, angels, demons, reptilians, and spirit guides. Speculation about whether these entities exist outside the mind or are purely internal hallucinations. Stats from research showing most users encounter intelligent, often benevolent beings. 00:40:00 - Machine Elf Queen and Reptilians Vivid account of a user's encounter with a voluptuous, green-skinned machine elf queen. Discussion about insectoid and reptilian entities during DMT trips that resemble alien abductions. Stories blur lines between alien encounters and psychedelic experiences. 00:50:00 - Jesus, Pets, and the Afterlife on DMT Encounters with “Space Jesus,” dead pets, and deceased relatives during DMT trips. Some users describe transformative emotional healing and major life changes. Link made between DMT visions and alien abduction experiences involving spirits of the dead. 01:00:00 - Alien Sphere Found in Colombia Analysis of a metallic orb recovered in Colombia, believed by some to be alien. Sphere has no welds, strange engravings interpreted using AI, and alleged circuitry inside. Theorized as a surveillance drone or part of an ancient defense grid. 01:10:00 - Haunted Dolls and Giant GPS Genitals Panic over the haunted doll Annabelle going missing is debunked. Review of GPS "penis art" created by fitness enthusiasts running elaborate routes. Consideration of whether this qualifies as performance art or absurdist satire. 01:20:00 - Harvard Body Part Trafficking Network Ongoing story of stolen human remains from Harvard Medical School's morgue. Deep dive into how parts were sold and how widespread the black market really is. Compilation of previous similar stories from 2019 to present. 01:30:00 - DIY Crosswalk Hero Arrested A man in Virginia paints his own crosswalk for pedestrian safety but is arrested. Discussed alongside other vigilante efforts like pothole filling and guerrilla street art. Commentary on local government inefficiency and citizen action. 01:40:00 - Japan Cracks Down on Baby Names Japan enacts new laws banning eccentric names like Pikachu and Caesar. Aimed at protecting children's well-being and social integration. Also covered: passenger attempts to open plane door mid-flight, prompting emergency landing. 01:50:00 - Kansas City: Global Capital of Dog Semen Kansas City is revealed to be the number one global hub for the storage and transportation of dog semen. The region is part of the Animal Health Corridor, which stretches from Manhattan, Kansas to Columbia, Missouri, home to 56% of the U.S. animal health diagnostics and pet food sales. Companies in the corridor conduct R&D and manage massive semen storage for horses, pigs, cattle, dogs, and more. Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, comment, news reporting, teaching, scholarship, and research ▀▄▀▄▀ CONTACT LINKS ▀▄▀▄▀ ► Phone: 614-388-9109 ► Skype: ourbigdumbmouth ► Website: http://obdmpod.com ► Twitch: https://www.twitch.tv/obdmpod ► Full Videos at Odysee: https://odysee.com/@obdm:0 ► Twitter: https://twitter.com/obdmpod ► Instagram: obdmpod ► Email: ourbigdumbmouth at gmail ► RSS: http://ourbigdumbmouth.libsyn.com/rss ► iTunes: https://itunes.apple.com/us/podcast/our-big-dumb-mouth/id261189509?mt=2
A newly available kind of genetic testing, called polygenic embryo screening, promises to screen for conditions that can include cancer, obesity, autism, bipolar disorder, even celiac disease. These conditions are informed by many genetic variants and environmental factors - so companies like Orchid and Heliospect assign risk scores to each embryo for a given condition. These tests are expensive, only available through IVF, and some researchers question how these risk scores are calculated. But what would it mean culturally if more people tried to screen out some of these conditions? And how does this connect to societal ideas about whose lives are meaningful? Brittany gets into it with Vardit Ravitsky, senior lecturer at Harvard Medical School and president of the Hastings Center, a non-partisan bioethics research center, and Katie Hasson, associate director of the Center for Genetics and Society, a nonprofit public affairs organization that advocates for responsible use of genetic technology.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy
Zirui Song is an associate professor of health care policy and medicine at Harvard Medical School and a general internist at Massachusetts General Hospital. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. Z. Song and J.M. Zhu. Primary Care — From Common Good to Free-Market Commodity. N Engl J Med 2025;392:1977-1979.
Dr. Robert Brooks is not only a professor at Harvard Medical School, but is one of the world's leading experts on the topic of resilience. In this episode, we get to listen to and learn from Bob, as he asked us to call him, on this crucial topic for kids today! He has so much wisdom and offers so much help in terms of how we help the kids we love learn that they can do hard things. We can't wait for you to listen in on this important episode. And would love to hear any of your favorite takeaways in the comments! . . . . . Owen Learns He Has What it Takes: A Lesson in Resilience Lucy Learns to Be Brave: A Lesson in Courage Grab your tickets today for the Raising Capable Kids Conference with David Thomas, Sissy Goff and special guests! Sign up to receive the monthly newsletter to keep up to date with where David and Sissy are speaking, where they are taco'ing, PLUS conversation starters for you and your family to share! Connect with David, Sissy, and Melissa at raisingboysandgirls.com . . . . . If you would like to partner with Raising Boys and Girls as a podcast sponsor, fill out our Advertise with us form. A special thank you to our sponsors: WAYFAIR: Shop a huge selection of outdoor furniture online. This summer, get outside with Wayfair. Head to Wayfair.com right now. EVERYDAY DOSE: Get 45% off your first subscription order of 30-servings of Coffee+ or Bold+. You'll also receive a starter kit with over $100 in free gifts including a rechargeable frother and gunmetal serving spoon by going to everydaydose.com/RGB or entering RGB at checkout. You'll also get FREE gifts throughout the year! Learn more about your ad choices. Visit megaphone.fm/adchoices
Today, we're diving into an important and growing health concern: colon cancer. Recent studies show that cases of colon cancer are becoming increasingly common in younger adults. In fact, the rate has doubled among people under 50 since the 1990s, prompting doctors to lower the recommended age for screening. So what can we do to protect ourselves and our loved ones? I'm joined by Harvard Medical School professor, Dr. Andy Chan, to talk about the importance of colon cancer screenings and how changes to our diet could help reduce the risk of this disease.
Obstetrician and gynaecologist, Dr Adam Urato, explains why he is concerned about the huge increase in medications now taken by pregnant women. A figure that has surged in the last few decades. Across the world, women are taking more drugs than ever before while pregnant. In the US, around 90% of women expecting a baby will now take some kind of medication during pregnancy Adam argues the notion a drug is safe until proved otherwise goes completely against the precautionary principle and common sense. He was one of the first doctors to highlight the risks of a synthetic hormone called Makena, which was supposed to reduce the risk of preterm birth. It was on the market for two decades, even when the evidence showed it didn't work, it took a further four years to get it withdrawn. Today Adam is particularly concerned about the number of women taking selective serotonin reuptake inhibitors - or SSRIs for short - in pregnancy and doesn't believe they are usually fully informed about the risk. Yet studies have shown that the medications can increase the likelihood of miscarriage, birth defects, an early birth, a low birth weight and postpartum haemorrhage. In some cases, there also appears to be a potential impact on the baby after birth. Dr Adam Urato is a board certified obstetrician and gynaecologist, who trained at Harvard Medical School and who practices in Massachusetts in the US. He has a particular interest in the risks and benefits of medications during pregnancy and has written a number of peer-reviewed papers on the topic. The host of the podcast, Liz Tucker is an award winning medical journalist and former BBC producer and director. You can follow Liz on Twitter at https://twitter.com/lizctucker and read her Substack newsletter about the podcast at https://liztucker.substack.com If you would like to support this podcast you can do so via Patreon at https://www.patreon.com/WhatYourGPDoesntTellYou or via PayPal at https://www.whatyourgpdoesnttellyou.com/support/ What Your GP Doesn't Tell You has been selected by Feedspot as one of the top 15 UK Medical Podcasts https://blog.feedspot.com/uk_medical_podcasts/
If you struggle with anxiety, this episode will change your life. In today's conversation, Mel sits down with Harvard Medical School psychologist and world-renowned anxiety expert Dr. David Rosmarin — and he's about to flip everything you think you know about anxiety on its head. By the end of this episode, you are going to know exactly what anxiety is, the things you're doing that are making it worse, and how you can look at it in a whole new way. You'll also learn exactly how to help somebody who is struggling with it. If you feel trapped by anxiety, or you've been trying to outrun it, what Dr. Rosmarin is about to share will set you free. He's here to share a simple way to stop spiraling thoughts, find clarity, and finally feel in control. Dr. Rosmarin is one of the world's leading experts on anxiety and the founder of The Center for Anxiety. He's an associate professor of psychology at Harvard Medical School and director of the Spirituality and Mental Health Program at McLean Hospital, one of the top psychiatric hospitals in the world. Whether your anxiety is keeping you up at night, holding you back at work, making parenting harder, or bringing life in general to a grinding halt, this episode will give you the tools — and the hope — you've been looking for. For more resources, click here for the podcast episode page. If you liked this episode, you'll love listening to this one next: How to Stop Negative Thoughts & Reset Your Mind for Positive Thinking.Connect with Mel: Get Mel's #1 bestselling book, The Let Them TheoryWatch the episodes on YouTubeFollow Mel on Instagram The Mel Robbins Podcast InstagramMel's TikTok Sign up for Mel's personal letter Subscribe to SiriusXM Podcasts+ to listen to new episodes ad-freeDisclaimer
Biosimilars, a group of drugs that are similar to biologic drugs, which are medications produced using living organisms and are often used to treat complex medical conditions. Biosimilars were first introduced to the prescription drug market about a decade ago and as of March, the FDA had approved scores of products that may be used interchangeably for some of the most expensive brand-name biologic pharmaceuticals, treating conditions such as diabetes and cancer. While biologics make up only about 2% of prescriptions, they account for as much as 46% of total drug spending in the U.S.The three guests on this podcast all have expertise on different aspects of this topic and discuss the use of biosimilar medicines in health care and the possible cost savings when they are used in place of originator biologic medications. Luca Maini is an economist who studies the pharmaceutical industry and is an assistant professor at Harvard Medical School. Chad Pettit is executive director of global government affairs for Amgen, a biotechnology company. Erin Glossop is a policy specialist at NCSL who follows state policies around pharmaceuticals.Maini discussed his research into how the introduction of biosimilars into a market affects the price of brand-name biologics. Pettit explained the perspective from the biotechnology industry and how he thinks the industry will develop in the next several years. Glossop explained how some states are developing bipartisan policy around biosimilar access and efforts to find cost-savings these products might offer. ResourcesAmgen BiosimilarsAssessing the Biosimilar Void in the U.S., IQVIABiosimilars in the United States 2023-2027, IQVIABiosimilar Uptake In The US: Patient And Prescriber Factors, Dongzhe Hong, et al.Coverage for Biosimilars vs Reference Products Among US Commercial Health Plans, James D. Chambers, et al.Exploring the Influence of Health Insurance Plans on Biosimilar Adoption Rates, Mariana Socal, et al.Factors Associated with Biosimilar Exclusions and Step Therapy Restrictions Among US Commercial Health Plans, Tianzhou Yu, et al.Luca Maini website
Today, I'm joined by Dr. Hasan Merali, and we're exploring What Toddlers Can Teach Us About Leadership. Hasan is an associate professor in the Department of Pediatrics at McMaster University and a pediatric emergency medicine physician at McMaster Children's Hospital in Hamilton, Ontario. He received his medical degree from Harvard Medical School and Master of Public Health degree from Johns Hopkins University. His research focuses on child injury prevention in low- and middle-income countries. He has published more than twenty-five peer-reviewed journal articles, and his work has been featured in The New York Times, BBC, CNN, Science, The Boston Globe, NBC, and Popular Science. His latest book is called Sleep Well, Take Risks, Squish the Peas: Secrets from the Science of Toddlers for a Happier, More Successful Way of Life. I'm excited to have him on the show to learn from his unique research on What Toddlers Can Teach Us About Leadership. Show resources: Dr. Hasan Merali's website Sleep Well, Take Risks, Squish the Peas book Dr. Merali's TEDx talk Sponsors: Cadre of Men Farrow Skin Care Salty Sailor Coffee Company Leader Connect The Qualified Leadership Series ____ Get all of Jon Rennie's bestselling leadership books for 15% off the regular price today! HERE Learn more about your ad choices. Visit megaphone.fm/adchoices
Pushing harder isn't always the answer. Sustainable high performance comes from aligning your mind and body—not burning them out.In this episode, holistic coach Tania St-Laurent—a certified osteopath in Canada with a degree in microbiology and over 20 years of experience as a movement specialist—shares how true performance begins with doing things the right way. Drawing from her background in science, mindfulness, and global experience across clinics, labs, and sports fields, Tania unpacks what sustainable performance actually looks and feels like.We explore how movement, nutrition, and recovery work together to create long-term energy and focus, why presence is the most underrated skill, and how starting small can lead to big change. Tania, also a certified Lifestyle and Wellness Coach from Harvard Medical School, gives you practical tools to optimize your well-being and perform without depletion.What You'll Learn in This Episode:Why Tania dedicated her life to exploring the connection between physical health and mental clarity.It's not about doing more—it's about doing the right things with intention.What it looks and feels like when you're in sync—covering movement, nutrition, and recovery.Simple, proven principles anyone can start applying today.Why multitasking backfires—and how presence can shift your entire performance.Why choosing one habit and doing it consistently leads to lasting change.Resources:Follow Tania St-LaurentVisit Tania's WebsiteListen to the previous episodes hereWelcome to Productivity MD where you can learn to master your time and achieve the 5 freedoms in life!Show Notes - How to Avoid Burning Out Your Nervous System and Achieve High Performance—In Body and Mind with Tania St. LaurentPlease subscribe and leave a review so you can help others who need the knowledge most discover this podcast. Visit https://www.productivitymd.com/ to learn more Here are 3 ways I can help you reclaim your time and be more productive:#1: Book a 15 minutes 1 Year 1-1 Peak Performance and Productivity Coaching Qualification Call now to learn more and take control of your time! #2: Join my Private Facebook Group and get full access to my 7-day Video Masterclass to 3X Your Productivity#3: Subscribe to Productivity MD Podcast (Formerly It's Not Rocket Science) on Health, Relationships, and Productivity or watch in YouTube.Follow Ann Tsung MD, MPH onAnn Tsung on FacebookAnn Tsung on YouTubeAnn Tsung on LinkedInAnn Tsung on InstagramAnn Tsung on Twitterhttps://www.productivitymd.com/2025/05/24/episode-74/
Are you unknowingly damaging your brain and raising your cancer risk with just one drink? Discover the alarming truth about alcohol from Dr. Sarah Wakeman, what every adult needs to know now. Dr. Sarah Wakeman is a senior medical director for substance use disorder at Massachusetts General Brigham Hospital, the number one research hospital in the world. She is also the Medical Director of the Mass General Hospital Addiction Consult Team and Assistant Professor of Medicine at Harvard Medical School. She explains: How alcohol is hijacking your dopamine system. Why no amount of alcohol is good for your brain. The shocking truth about moderate drinking. How doctors are failing addiction patients on a daily basis. Why 1 in 3 people will struggle with alcohol. 00:00 Intro 02:23 Sarah's Mission 02:52 Sarah's Education and Experience 03:40 Issues With Addiction Treatment in the Modern World 04:31 What Is Addiction? 05:48 What Things Are Capable of Being Addictive? 06:47 Physiological Dependence vs. Addiction 07:25 Scale of the Problem: Why Should People Care? 08:59 Is Society Getting Better or More Addicted? 09:32 Substance-Related Deaths During the Pandemic 10:22 What Drives People to Use Substances? 12:24 Substances' Effects on the Brain 14:29 Does Trauma at a Young Age Increase Addiction Risk? 16:36 The Opposite of Addiction Is Connection 18:11 Why Addiction Matters to Sarah 19:02 Living With a Family Member Struggling With Addiction 20:43 Who Is Sarah Trying to Save? 22:57 Change Happens When the Pain of Staying the Same Is Greater Than the Pain of Change 25:53 Misconceptions About Alcohol 28:15 Is There a Healthy Level of Alcohol Consumption? 28:50 Is One Drink a Day Safe for Health? 30:38 Link Between Moderate Drinking and Cancer 33:23 Types of Cancer Linked to Alcohol Consumption 34:51 Cancer Risk Among Heavy Drinkers 35:31 Heavy Drinking and Comorbidities as Cancer Risk Factors 36:20 How Alcohol Drives Cancer Mechanisms 38:00 Alcohol and Weight Gain 38:54 The Role of the Liver 42:07 Liver's Ability to Regenerate 46:37 How Alcohol Causes Brain Deterioration 47:23 Other Organs Affected by Alcohol 48:00 Alcohol's Impact on the Heart 49:08 Body Fat Percentage and Alcohol Tolerance 50:05 Does High Alcohol Tolerance Prevent Organ Damage? 50:46 What Is a Hangover? 52:14 Balancing the Risks and Benefits of Alcohol 53:47 Is Rehab Effective for Addiction? 56:50 Psychedelic Therapy for Addiction 57:36 GLP-1 Medications for Addiction Treatment 59:03 Ads 59:59 Celebrity Addictions 1:02:24 Stigma Around Addiction 1:04:41 Addiction Cases That Broke Sarah's Heart 1:12:43 Is Empathy Positive Reinforcement for Addicted Individuals? 1:15:34 Setting Boundaries With an Addicted Person 1:18:57 Motivational Interviewing to Support Recovery 1:22:19 Finding Motivation for Positive Change 1:26:03 Habits to Support Addiction Recovery 1:29:12 Ads 1:30:18 Can the Brain Recover From Addiction? 1:34:55 Unexpected Sources of Addictive Behavior 1:35:35 How Sarah Copes With Difficult Addiction Cases 1:37:10 Importance of Language Around Addiction 1:41:40 How Labels Limit People's Potential 1:46:05 Sarah's Upcoming Book You can find out more about Dr. Sarah's profile, here: https://bit.ly/4mxu191 Ready to think like a CEO? Gain access to the 100 CEOs newsletter here: bit.ly/100-ceos-megaphone The 1% Diary is back - limited time only: https://bit.ly/3YFbJbt The Diary Of A CEO Conversation Cards (Second Edition): https://g2ul0.app.link/f31dsUttKKb Get email updates: https://bit.ly/diary-of-a-ceo-yt Follow Steven: https://g2ul0.app.link/gnGqL4IsKKb Research document: https://drive.google.com/file/d/11xEfVt4S6nFyJw8jTJNysBPVUra2CzWK/view?usp=sharing Sponsors: Ekster - https://partner.ekster.com/DIARYOFACEO with code DOACLinkedin Ads - https://www.linkedin.com/DIARY Learn more about your ad choices. Visit megaphone.fm/adchoices
Alice Rothchild's path to becoming an anti-Zionist Jew took many years, many hard conversations, and required a lot of critical self-reflection. But she is part of a growing, powerful chorus of Jewish voices around the world speaking out against Israel's Occupation of Palestine and ethnic cleansing of Palestinians—and she is urging others to join that chorus. “The time is long overdue for liberal Zionists to find the courage to take a long hard look at their uncritical support for the actions of the Israeli state as it becomes increasingly indefensible and destabilizing, a pariah state that has lost its claim to be a so-called democracy (however flawed) that is endangering Jews in the country and abroad as well as Palestinians everywhere,” Rothchild writes in Common Dreams. In the latest installment of The Marc Steiner Show's ongoing series “Not in Our Name,” Marc speaks with Rothchild about her path to anti-Zionism, the endgame of Israel's genocidal assault on Gaza, and the need to liberate Jewish identity from the Zionist state of Israel.Alice Rothchild is a physician, author, and filmmaker with an interest in human rights and social justice. She practiced ob-gyn for almost 40 years and served as Assistant Professor of Obstetrics and Gynecology at Harvard Medical School. She is the author of numerous books, including: Broken Promises, Broken Dreams: Stories of Jewish and Palestinian Trauma and Resilience; Condition Critical: Life and Death in Israel/Palestine; Old Enough to Know, a 2024 Arab American Book Award winner; and Inspired and Outraged: The Making of a Feminist Physician. Rothchild is a member of the Jewish Voice for Peace Health Advisory Council and a mentor-liaison for We Are Not Numbers.Producer: Rosette SewaliStudio Production: David HebdenAudio Post-Production: Alina NehlichHelp us continue producing radically independent news and in-depth analysis by following us and becoming a monthly sustainer.Sign up for our newsletterLike us on FacebookFollow us on TwitterDonate to support this podcast
John's monologue first discusses Jake Tapper's new book "Original Sin" which blames White House staffers and the media for covering up President Biden's supposed cognitive decline. He also talks about Trump in Saudi Arabia, where he met with Arab business leaders, hoping to land the next great freebie. He also announced an imminent cessation of sanctions on Syria, a major policy shift encouraged by both Saudi Arabia and Turkey. Then, Professor Corey Brettschneider returns to debate about Supreme Court Justice John Roberts' weak Trump rebuke, whether a president can suspend habeas corpus, and birthright citizenship which is now heading to the Supreme Court. Next, John interviews Dr. Anahita Dua - who is an Assistant Professor at Harvard Medical School and a vascular surgeon at the Massachusetts General Hospital. They talk about Trump's choice for Surgeon General: Right-Wing wellness Influencer Casey Means. And then finally, comedian Keith Price is back to joke with listeners about the latest trends and the firehose of dumpster fire news coming from the GOP and "Man-Baby".See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Can five days of fasting change your life? A new approach called the fasting mimicking diet is transforming lives. Discover the science behind fasting without starving, how to trigger autophagy and cellular regeneration, and why this new paradigm in lifestyle medicine could reduce insulin resistance and even reverse type 2 diabetes. Dr. William Hsu, Chief Medical Officer at L-Nutra and former Harvard Medical School faculty member, joins Chuck Carroll in this groundbreaking episode of The Exam Room Podcast recorded in Rochester, MN. — — SHOW LINKS — — L-Nutra https://l-nutra.com — — EVENTS — — Exam Room LIVE: Longevity and Muscle Building GreenFare Organic Restaurant Where: Herndon, VA When: May 28, 2025 Tix: https://bit.ly/ERTixGFMay2025 — — — NHA Conference Where: Cleveland, OH When: June 26-29, 2025 Tix & Speakers: https://www.healthscience.org/2025-nha-conference — — — International Conference on Nutrition in Medicine Where: Washington, DC When: August 14-16, 2025 Tix & Speakers: https://www.pcrm.org/icnm — — BECOME AN EXAM ROOM VIP — — Sign up: https://www.pcrm.org/examroomvip — — THIS IS US — — The Exam Room Podcast Instagram: https://www.instagram.com/theexamroompodcast — — — Chuck Carroll Instagram: https://www.instagram.com/ChuckCarrollWLC Facebook: https://www.facebook.com/ChuckCarrollWLC X: https://www.twitter.com/ChuckCarrollWLC — — — Physicians Committee Instagram: https://www.instagram.com/physicianscommittee Facebook: https://www.facebook.com/PCRM.org X: https://www.twitter.com/pcrm YouTube: https://www.youtube.com/user/PCRM Jobs: https://www.pcrm.org/careers — — SUBSCRIBE & SHARE — — 5-Star Success: Share Your Story Apple: https://apple.co/2JXBkpy Spotify: https://spoti.fi/2pMLoY3 — — — Please subscribe and give the show a 5-star rating on Apple Podcasts, Spotify, or many other podcast providers. Don't forget to share it with a friend for inspiration!
Which side is your good side? You know, the side of your face you point toward the camera when someone takes your picture. We all have a good side. And I bet I know which one yours is. https://newsfeed.time.com/2012/04/24/which-side-is-your-good-side-here-comes-the-science/ You are exposed to a lot of music every day. Sometimes it is music you seek out and want to listen to as well as music that plays in the background – in stores, in elevators, in a doctor's office. All that music affects your brain in interesting ways. Here to explain how is Sara Leila Sherman. She is a musician and educator, who studied and pioneered innovation in music as a tool for learning and personal growth. She is coauthor of the book Resonant Minds: The Transformative Power of Music, One Note at a Time (https://amzn.to/4jDM6Aq). Many prescription drugs do amazing things to help people. Still, there are frequent stories of drugs that go wrong. They either don't work or they turn out to cause harm or even death. Isn't the FDA supposed to make sure that doesn't happen? How do bad drugs get approved? Is the process broken? Here to offer some great insight into this is Jerry Avorn, MD. Who is also a professor of medicine at Harvard Medical School. He created a leading research center at Harvard to study medication use, outcomes, costs, and policies and has written hundreds of papers that have appeared in medical literature as well as opinion pieces in The New York Times and The Washington Post. He is author of the book Rethinking Medications: Truth, Power, and the Drugs You Take (https://amzn.to/4lRlT2E) Many people look back fondly on the good old days. Were they really that good? For some, the past seems so much better than the present, and they love to reminisce fondly about a better and simpler time. Listen as I explain why the past looks so wonderful to many of us and just how good it really was. https://www.elephantjournal.com/2014/08/why-we-long-for-the-good-old-days-why-they-never-really-existed-marianne-stenger/ PLEASE SUPPORT OUR SPONSORS!!! FACTOR: Eat smart with Factor! Get 50% off at https://FactorMeals.com/something50off TIMELINE: Get 10% off your order of Mitopure! Go to https://Timeline.com/SOMETHING INDEED: Get a $75 sponsored job credit to get your jobs more visibility at https://Indeed.com/SOMETHING right now! QUINCE: Elevate your shopping with Quince! Go to https://Quince.com/sysk for free shipping on your order and 365 day returns! SHOPIFY: Nobody does selling better than Shopify! Sign up for a $1 per-month trial period at https://Shopify.com/sysk and upgrade your selling today! Learn more about your ad choices. Visit megaphone.fm/adchoices