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Most conversations about longevity focus on tactics. This episode breaks down the biology underneath them. You'll hear a systems level analysis of how insulin signaling, mTOR, mitochondrial function, inflammation, and nutrient sensing interact to determine biological age, disease risk, and long term human performance. This is not surface level biohacking. It is a deep dive into the mechanisms that actually control aging, metabolism, muscle preservation, and brain optimization, and why most anti aging strategies fail when they ignore these foundations. This all-time classic episode from 2024, has host Dave Asprey joined by Mark Hyman, a practicing physician and one of the most respected leaders in functional medicine. Dr. Hyman is the founder and senior advisor of The UltraWellnessCenter, the founder and former head of strategy and innovation at the Cleveland Clinic Center for Functional Medicine, and a long time advocate for treating root causes instead of managing disease. With over 30 years of clinical experience, his work focuses on restoring mitochondrial health, optimizing metabolism, reversing chronic disease, and slowing biological aging using science backed interventions. Together, Dave and Mark dismantle common myths around protein, carnivore diets, ketosis, fasting, supplements, and longevity drugs. They explain why sugar accelerates aging faster than protein, how mTOR must cycle instead of staying suppressed, and why muscle, mitochondria, and metabolic flexibility matter more than calorie restriction. The conversation also covers nootropics, sleep optimization, neuroplasticity, AI driven diagnostics, and how functional medicine reframes aging as a reversible biological process rather than an inevitable decline. You'll learn: • How insulin and nutrient sensing control aging speed • Why mitochondria sit at the center of longevity and disease • The truth about mTOR, fasting, and protein intake • How ketosis and metabolic flexibility protect long term health • Where supplements and nootropics actually fit in brain optimization • Why functional medicine outperforms symptom based care • How AI and advanced testing are reshaping modern medicine Thank you to our sponsors! - MASA Chips | Go to https://www.masachips.com/DAVEASPREY and use code DAVEASPREY for 25% off your first order. -ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order. -OneSkin | Try OneSkin for 15% off with code DAVE at https://www.oneskin.co/DAVE. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: longevity biohacking, functional medicine longevity, biological age reversal, mitochondria and aging, mTOR pathway aging, insulin resistance and aging, metabolic flexibility, fasting and longevity, ketosis and metabolism, protein intake and mTOR, muscle and longevity, inflammaging, chronic inflammation aging, mitochondrial dysfunction, nutrient sensing pathways, rapamycin longevity, metformin longevity debate, carnivore diet longevity, sugar and aging, brain optimization longevity, neuroplasticity and aging, sleep optimization biohacking, supplements for longevity, anti aging metabolism, human performance optimization, Dave Asprey longevity, Mark Hyman longevity Resources: • Mark's Website: https://drhyman.com/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 0:45 - Introduction 4:49 - Aging as a Treatable Disease 7:50 - The Hallmarks of Aging 14:23 - Nutrient Sensing and Longevity Switches 17:37 - Time Restricted Eating and Autophagy 20:44 - The Four Longevity Pathways 21:49 - Metformin Debate 25:30 - Ozempic and Weight Loss 28:42 - Rapamycin and mTOR 36:23 - Meat, Protein, and Aging 39:46 - Protein Quality and Muscle Synthesis 45:50 - Protein Timing for Muscle Building 48:08 - Metabolic Flexibility 51:32 - Inflammaging 55:26 - Zombie Cells and Senescence See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Team Simon here! Thank you for being part of such an incredible year—and for helping us grow the podcast through your support, sharing it with others, and showing up week after week. We love seeing your comments and hearing what resonates with you.A Bit of Optimism returns on January 27, 2026, with brand-new episodes we think you're really going to enjoy. Until then, we're revisiting a few of our favorite moments from the past year.We're kicking things off with one of our most popular episodes—the conversation we filmed in London with Mo Gawdat. As a “Happiness Expert,” Mo teaches us that happiness is a choice, even if it's not always an easy choice to make.Mo had to face an impossible choice. Before he was a bestselling author and podcast host, Mo worked a lucrative career as Chief Business Officer at Google X. He reached the heights of business influence and amassed a fortune by 29. And yet, he was miserable. It was only after the tragic death of his 21-year-old son Ali that Mo was forced to confront the truth.Mo now dedicates his life, work, and research to figuring out how human beings can be happier, and he's on a mission to make 1 billion people happy. He shares what he's learned – that happiness is both a choice and our default setting, how to trick our brains out of survival mode, and why the happiest emotions we feel are rooted in the present, not the past or future.This… is A Bit of Optimism.---------------------------To learn more about Mo and his work, check out: https://www.mogawdat.com/
Is "White Noise" too harsh for you? Does your brain feel like it's constantly vibrating with stress or ADHD chatter?In this episode of Calming Anxiety, we step away from the silence and tune into Green Noise—the specific sound frequency of nature.Unlike the static of white noise, Green Noise sits in the mid-frequency range (like wind in heavy trees or a rushing river), which research suggests is the "Goldilocks" zone for the human nervous system.Whether you need 10 minutes to hack your focus for deep work or you need to "wash" your brain of anxiety before bed, this guided "Forest Bathing" session is your reset button.In this session, we will covers:The Green Frequency: Why your nervous system prefers the sound of wind and water over pure silence.Virtual Forest Bathing: A guided visualization to transport you from your desk (or bed) to an ancient, cool forest.The "Stream" Technique: How to visualize your racing thoughts flowing away like water over smooth stones.Somatic Safety: Using sound vibration to tell your body, "You are safe now."
Peptide therapy is turning out to be one of the most exciting frontiers of modern regenerative medicine.Peptides are nature-derived, highly targeted molecules that are already in your body, but when used therapeutically, they can guide healing, enhance function, and even reverse aspects of aging.I walk you through the most powerful peptides, from BPC-157 for tissue and gut repair, to epitalon for extending biological youth, to brain peptides like Dihexa and Cerebrolysin that can help rebuild neural pathways.There's likely a peptide for anything you can think of. Whether it's for boosting your immune system, improving sleep, enhancing mood, supporting weight loss, or regenerating skin and hair.I'll also look at cutting-edge research, including studies on cardiovascular rejuvenation, sexual function peptides like PT-141, and even mitochondrial peptides that fuel your cells' energy engines.
It's our annual Year in Review episode as the guys look back at 2025! Join Chris the Brain, "The Toyman" Chris DePetrillo, and Ryan Campbell as they share their Top 5 movies of the year, and pay tribute to the ones we lost in 2025. Plus, the most read posts over at BulletproofAction.com, and the most listened to episodes of the Bulletproof Podcast, news on Episode 200, and everyone's favorite... the Search Terms of 2025! Learn more about your ad choices. Visit megaphone.fm/adchoices
Lauren explores how rhythm regulates both the nervous system and organizations, showing how predictable routines create safety, clarity, and capacity, while chaos increases stress and burnout.She shares practical examples of daily, weekly, monthly, and quarterly rhythms leaders can use to replace urgency with coherence, and invites listeners to try one regulating rhythm and notice how it shifts energy and pace over time.Sign up for the University of Pennsylvania Behavior Breakthrough Accredited CourseLearn about the Staff Sustainability System a proven system to reduce burnout at the rootOther related resources from Five Ives: Blog Post: Why Traditional Employee Wellness Programs Fail (And What Works Instead)Survive Mode: Recognizing When Your Organization is in CrisisWhat are the Five Ives?Podcast:When Culture DysregulatesGrowth & Feedback Without FearOnboarding as Co-RegulationPolicy as a Nervous SystemMeetings that Calm, Not DrainThe Regulated Organization: What it Means to be a Regulated OrganizationRetain: Sustaining Staff, Culture, and CapacityReinforce- Ensuring that Change becomes Cultural Muscle Memory Reset: Moving from Relief to Real TransformationThe Regulated Team: Creating Cultures that BreatheHive- The Last Stage of the Five IvesThrive- The Fourth Stage of the Five IvesStrive- The Third Stage of the Five IvesRevive- The Second Stage of the Five IvesSurvive- The First Stage of the Five IvesOur Online Programs: Behavior BreakthroughPolicing Under PressureBoard Governance TrainingUniversity of Pennsylvania Behavior Breakthrough Accredited CourseSubscribe to our mailing list and find out more about Stress, Trauma, Behavior and the Brain!Check out our Facebook Group – Five Ives!Five Ives Website websiteThe Behavior Hub blogIf you're looking for support as you grow your organization's capacity for caring for staff and the community, we would love to be part of that journey. Schedule a free discovery call and let us be your guideAs an Amazon Associate, I earn from qualifying purchases.
Let's connect on Instagram @julieoeder Ever feel like your own brain is working against you? In this episode, we're calling it out. Your brain isn't broken. It's just doing what it was designed to do keep you safe, small, and stuck in familiar patterns. If you've ever told yourself you're not ready yet, that you need more confidence, or that other people are just better at starting things than you, this episode is for you. We're breaking down the most common lies your brain tells when you're on the edge of starting a business or bringing an idea to life and reframing them into truths that actually move you forward. You'll learn why confidence doesn't come before action, how overthinking disguises itself as preparation, and what it really takes to become the version of you who finally starts. This episode will help you stop listening to the voice that keeps you stuck and start trusting yourself enough to move anyway. If you're ready to take your first brave step, this conversation is for you.
Episode 105 | Neuromodulation Explained: The Future of Drug-Free Brain Therapy with SOZO Brain Center In this episode of the Neurologic Wellness Podcast, host Dr. David Traster sits down with Matthew Papadopoulos, CEO of the Sozo Brain Center, one of the world's leading authorities in non-invasive neuromodulation. The Sozo Brain Center, based in Cyprus, is internationally recognized for delivering cutting-edge, drug-free brain stimulation therapies for complex neurological and mental health conditions. The word Sozo comes from ancient Greek, meaning "to save" — a mission reflected in their life-changing clinical outcomes. In this conversation, we explore: What neuromodulation really is and how non-invasive brain stimulation works Why protocols matter more than devices How combining stimulation with targeted cognitive and motor tasks enhances neuroplasticity Conditions treated including dementia, Parkinson's, autism, chronic pain, and mental health disorders EEG brain mapping, outcome tracking, and personalized treatment timelines Using TMS, TPS, tDCS, tACS, Vagal Nerve Stimulation, Tongue Electric Stimulation Training doctors globally to expand access to neuromodulation Dr. Traster shares why he considers Sozo Brain Center the global gold standard in neuromodulation and how this technology is redefining neurological and mental health care worldwide. Recovery is possible. The brain can heal. Neurologic Wellness Institute Locations: Boca Raton, FL | Chicago, IL | Wood Dale, IL | Waukesha, WI Learn more or schedule a consultation: neurologicwellnessinstitute.com Subscribe for more conversations on brain health, neuroplasticity, and cutting-edge neurological care.
It might not be too Christmasy but it takes place around Christmas so it counts! We're talking about The Brain from 1988.
What if the real power in your life isn't what you know, but what you know that everyone else knows you know?Money only works because we all believe everyone else believes in it. Governments stand because we assume everyone else will follow the rules. Even love, status, trust, and cancel culture are driven by invisible social agreements that live in our shared mind.In this episode, I sit down with Dr. Steven Pinker, Harvard psychologist, cognitive scientist, bestselling author, and one of Time's “100 Most Influential People in the World Today,” to decode the science of common knowledge and how it shapes everything from money and power to social media, revolutions, and your daily relationships.We talk about why some ideas go viral and others don't, why cancel culture and public shaming are so effective, why dictators fear free speech, and how misinformation hijacks our “collective brain.” Steven also shares powerful tools from his books Rationality and When Everyone Knows That Everyone Knows to help you think more clearly, protect yourself from cognitive biases, and become a better learner and communicator in a noisy, hyper-connected world.If you've ever wondered why people follow the crowd, why markets boom and crash, why social norms feel so powerful, or how to stay rational when everyone is yelling online, this conversation will help you see the hidden architecture behind human behavior – and use that insight to upgrade your thinking, your learning, and your life./ / / Ready to upgrade your brain? / / /Choose your own adventure. Below are the best places to start:>>> Master Exceptional Memory Skills in 31 Days>>> Discover Your Unique KWIK BRAIN C.O.D.E To Activate Your Genius>>> Unlock New Levels of Cognitive PerformanceTake your first step by choosing one of the options above, and you will find everything you need to ignite your brilliant brain and unlock your exceptional life, allowing you to achieve and surpass all of your personal and professional goals.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
#671: Welcome to Greatest Hits Week — five days, five episodes from our vault, spelling out F-I-I-R-E. Today's letter F stands for Financial Psychology. And we're diving deep with a conversation that changed how thousands of our listeners think about money. This episode originally aired in November 2022, but the insights feel more relevant than ever. Dr. Daniel Crosby reveals why your brain is your portfolio's worst enemy — and what you can do about it. ______ Money is the number one stressor in American lives. Every single year. Without exception. That's what Dr. Daniel Crosby discovered when he looked at decades of research from the American Psychological Association. In this rerun episode from our Greatest Hits Vault, Crosby joins us to reveal why your brain sabotages your investment decisions. He's both a clinical psychologist and behavioral finance expert. His findings will change how you think about money. Your body hijacks your financial judgment in strange ways. For example: People who need to pee become more risk-averse investors. It's called inhibitory spillover. When you're controlling your bladder, you also restrict your financial decisions. Here's another one: judges give harsher sentences when they're hungry. Thousands of court decisions prove it. The best predictor of whether you get jail time? When the judge last ate. We explore four behavioral risks that destroy wealth: ego, conservatism, attention, and emotion. Crosby shares data that stock pickers rarely hear: 74 percent of individual stocks have a lifetime expected return of zero. Three out of four companies eventually go bankrupt. Yet people keep betting on single stocks, dreaming they'll find the next Apple. Value investors suffer from depression and social isolation. Why? Because contrarian investing fights our deepest evolutionary wiring. Humans survived through cooperation. It's literally our only advantage over other animals. Bears have claws. Turtles have shells. We have teamwork. Crosby shares the Ash experiment, which shows how peer pressure warps reality. When nine people give the wrong answer about line lengths, three-quarters of participants follow along. New brain scans reveal something darker: social pressure physically changes how people see the lines. Their perception actually shifts. We discuss solutions through Crosby's "three E's": education, environment, and encouragement. Reading about biases won't fix them. You need systems and people. One powerful study: people who saw their children's photo for five seconds before banking saved twice as much money. The conversation reveals that money problems don't disappear with wealth. They just change form. Timestamps: Note: Timestamps will vary on individual listening devices based on dynamic advertising run times. The provided timestamps are approximate and may be several minutes off due to changing ad lengths. (00:00) Finance as America's top stressor (02:33) Psychology moving from brokenness to wellness (04:33) Money touches every part of life (07:33) Income plateaus and happiness (10:13) How hunger affects financial decisions (13:38) We're wired wrong for investing (17:28) Laziness and cognitive shortcuts (23:43) Cooperation as human survival trait (26:43) Four behavioral risks (32:13) Ego and overconfidence (37:48) Conservatism and familiarity bias (46:38) Three E's of behavior change (50:23) Attention risk and probability (54:48) Emotion derails decisions (58:28) When fear helps versus hurts Learn more about your ad choices. Visit podcastchoices.com/adchoices
Beautiful soul, this episode is for any woman navigating perimenopause, menopause, or feeling confused by the emotional, mental, and physical shifts happening in her body. Julie is joined by Dr. Mindy Pelz for a powerful, grounded conversation that reframes hormonal change not as something breaking down, but as an initiation into wisdom, clarity, and deeper self-trust. Together, they explore why symptoms like brain fog, anxiety, irritability, sleep disruption, and emotional intensity are not failures, but messages from the body asking to be listened to differently. This episode gently reframes menopause as a spiritual and biological transition, intuition as a skill that strengthens with age, and metabolic health as a foundation for emotional balance. It is especially supportive for women feeling unseen by the medical system, overwhelmed by symptoms, or sensing that this season of life is calling them into a new level of leadership, truth, and alignment. Episode Chapters (4:06) Welcoming Dr. Mindy Pelz and her work in women's health (5:20) Why women are unprepared for perimenopause and menopause (9:14) Estrogen, progesterone, testosterone, and emotional shifts (16:12) Metabolic health, A1C, and symptom reduction (23:25) Fasting, food rhythms, and honoring the female body (30:16) Brain rewiring, intuition, and the wise woman phase (37:25) Hormone therapy, neurochemicals, and mental clarity (42:26) Relationships, boundaries, and identity changes (48:13) Anxiety, rumination, and nervous system support (58:49) Closing angel message: Heaven lives within you Work with Julie & Your Angels If you've been feeling the nudge I want to hear my angels clearly, I want to work with them every day, here's how to go deeper:
Lose Fat With My Clubhouse App HERE https://theclubhouse1.lpages.co/erfclubhouse-app-info On this episode, I talk about why most people quit their fitness journey at 31 degrees, right before the ice starts to melt. I dive into the science behind self-sabotage and give you practical analogies and mental tools to help you win those weak moments when you're tempted to go off track. Lose Fat With Personalized 1:1 Coaching HERE https://theclubhouse1.lpages.co/1to1-coaching Free Calorie Calculator https://ericrobertsfitness.com/free-calorie-calculator/ 20% Off Legion Athletic Supplements Code “ERIC” HERE https://legionathletics.rfrl.co/qj2dy Youtube Channel https://www.youtube.com/@ericrobertsfitness
Exploring GLP-1 agonists in a new light, Matt examines a review that positions these metabolic hormones as potential brain defenders. He details their surprising presence in memory centers and their capacity to combat the "biological rust" of oxidative stress and neuroinflammation.Matt critically evaluates the gap between robust animal models and the unwritten chapter of human trials, while highlighting the vital link between metabolic health and sleep. He argues that biology is not siloed; supporting the body's metabolic "power grid" through sleep provides the integrated care the brain needs to withstand complex insults.Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.In a supplement industry where trust is critical, Matt uses podcast supporter Puori. Their protein powders are free from hormones, GMOs, and pesticides, with every single batch third-party tested for over 200 contaminants. For protein you can trust, save 20% at puori.com/mattwalker.Another sponsor is UPLIFT Desk whose V3 Standing Desk helps boost circulation and concentration with a sturdy, customizable design that gets you moving while you work. Visit upliftdesk.com/walker and use code WALKER for 4 free accessories and a 15-year warranty.As always, if you have thoughts or feedback you'd like to share, please reach out to Matt:Matt: Instagram @drmattwalker, X @sleepdiplomat, YouTube: https://www.youtube.com/channel/UCA3FB1fOtY4Vd8yqLaUvolg
Discover how vagus nerve stimulation (VNS) can transform your gut health, brain function, and autoimmune conditions. In this comprehensive episode, we break down the science behind vagal tone, review the best VNS devices on the market, and share our clinical protocols for optimal results.
Love Strategies: Dating and Relationship Advice for Successful Women
Are you a dopamine dater, chasing excitement, or a serotonin dater, seeking stability? Discover the science behind your dating style and how it affects your relationships. Decode your brain's chemistry and transform your love life.Learn how men actually think in my free training - https://go.lovestrategies.com/virtualOriginally Aired: Feb. 01, 2025NEXT STEP: Book a complimentary Love Strategy Session and let us help you attract love this year: https://go.lovestrategies.com/session
Think brain fog, rage, and restlessness means you're falling apart? Your brain isn't backfiring— it's rewiring for power and clarity. Get ready to rethink everything you know about complicated emotions and menopause with Dr. Mindy Pelz, bestselling author of “Age Like a Girl." Mindy helps us reframe menopause as a "neurochemical storm" that upgrades your brain for leadership. Discover the evolutionary science behind this transformation, how your hormonal "girl gang" shifts during menopause, why depression and rage are signals not to ignore, and why postmenopausal women are biologically wired to lead. Learn to work with your body's upgrade instead of fighting it. FOLLOW A CERTAIN AGE Instagram Facebook LinkedIn GET INBOX INSPO: Sign up for our newsletter AGE BOLDLY We share new episodes, giveaways, links we love, and midlife resources Learn more about your ad choices. Visit megaphone.fm/adchoices
Like many of its genre, the film “Elf” connects Christmas spirit to the sorts of bonds that hold together families and communities, despite their inevitable tendencies towards conflict and dissolution. Wes & Erin discuss this 2003 classic, what it means to believe in Christmas, and how this is connected to the possibility of a genuine community. Upcoming Episodes: “Julius Caesar.” Pre-order Erin’s forthcoming book “Avail” here: http://subtextpodcast.com/avail For bonus content, become a paid subscriber at Patreon or directly on the Apple Podcasts app. Patreon subscribers also get early access to ad-free regular episodes. This podcast is part of the Airwave Media podcast network. Visit AirwaveMedia.com to listen and subscribe to other Airwave shows like Good Job, Brain and Big Picture Science. Email advertising@airwavemedia.com to enquire about advertising on the podcast. Follow: Twitter | Facebook | Website
The holidays look simple from the outside, but inside the brain they are anything but. This week, Dr Bray explores why this season stirs up so much emotion and how small rituals, tiny moments of connection, and simple sensory cues can create the holiday season you really want. You will hear stories, science, and a few practical ideas and tips you can use to bring more meaning and calm into the next few weeks. If the holidays feel wonderful, complicated, or a little of both, this episode will help you create a season that feels grounded, joyful, and full of meaning. Quotes by Dr. Bray "Christmas and the holidays are never just a date—they're a pattern the brain has learned over a lifetime." "The brain holds a map of belonging, loss, joy, comfort, and hope." "Rituals are small signals to the brain that say, 'This moment matters.'"
In this episode, I break down why you can feel exhausted all day but suddenly wired the moment you try to sleep. We talk about how cortisol, melatonin, blood sugar, and perimenopause all play a role, and what you can actually do to get real rest. What we cover: 1. Cortisol and melatonin basics Your circadian rhythm depends on high cortisol in the morning and low cortisol at night. If cortisol spikes in the evening, you will feel "tired but wired." Taking melatonin will not help if melatonin is normal and cortisol is the real problem. 2. How DUTCH testing reveals the root cause A DUTCH hormone test shows: Your full cortisol pattern throughout the day Melatonin output Blood sugar, nutrient, and inflammation markers Estrogen and progesterone levels that may affect sleep This is why DUTCH is so helpful for women who have tried every sleep aid with no results. One client had perfect melatonin but high nighttime cortisol. Once we targeted that, her sleep finally improved. 3. Simple tools to try tonight Protein before bed: At least 20 grams to stabilize blood sugar and quiet cortisol. Nighttime routine: Lower lights, cooler bedroom, weighted blanket, deep breathing, red light, warm bath. Journaling: Empty your brain before bed so you are not carrying mental clutter into sleep. 4. Perimenopause and sleep changes Falling progesterone can make it harder to relax or stay asleep. Supporting progesterone naturally and adding magnesium or B vitamins at night can help. 5. Herbal and nutritional support Adrenal tincture to support cortisol regulation Sleep tincture to calm the nervous system Magnesium in the evening to relax muscles and reduce tension Consistency matters. Sleep often improves gradually over three or more weeks. Why a DUTCH test is your next step If you are done guessing, DUTCH testing shows exactly: Whether cortisol, melatonin, blood sugar, or inflammation is keeping you awake What your hormones are doing at night Which specific areas to target This saves time, money, and frustration so you can finally sleep again. You can order a DUTCH test here and get a personalized review and plan: https://drbethwestie.com/dutch-hormone-testing/ Better sleep starts with understanding what your hormones are doing behind the scenes.
Unexplained chronic pain/illness trapping you in ND chaos? In this episode of Adulting with Autism, host April dives into neuroplastic symptoms—brain-generated conditions from stress/trauma (1 in 6 adults, higher in autism/ADHD)—with Dr. David Clarke, MD (Internal Medicine/Gastroenterology), ATNS President (nonprofit ending pain epidemic), and podcast host "The Story Behind the Symptoms." Treating 7000+ patients, Dr. Clarke's book "They Can't Find Anything Wrong" reveals real symptoms (fibromyalgia/migraines/IBS/long COVID) unresponsive to physical treatments—focus on stress sources for recovery. Key insights: Neuroplastic basics: Brain rewires from stresses (current emotions/childhood adversity/being "different" like ND); no structural cause but real (scans prove circuits change). ND link: Masking/difference adds pressure; symptoms signal distress (e.g., pain only at work triggers). Screening: Free 12-question quiz at symptomatic.me (
NPR Books Editor Petra Mayer Petra was a great friend of mine. Tragically, she suddenly passed away in November 2021. Her New York Times Obituary noted her many accomplishments. I called her my dear friend. Enjoy this encore episode of one of the best people ever. Website: https://IzoldaT.com Book Your Discovery Call: https://calendly.com/izoldat/discovery-call New Play Exchange: https://newplayexchange.org/users/90481/izolda-trakhtenberg This episode is brought to you by Brain.fm. I love and use brain.fm! It combines music and neuroscience to help me focus, meditate, and even sleep! Because you listen to this show, you can get a free trial and 20% off with this exclusive coupon code: innovativemindset. (affiliate link) URL: https://brain.fm/innovativemindset It's also brought to you by my podcast host, Podbean! I love how simple Podbean is to use. If you've been thinking of starting your own podcast, Podbean is the way to go!** Listen on These Channels Apple Podcasts | Spotify | Stitcher | Podbean | MyTuner | iHeart Radio | TuneIn | Deezer | Overcast | PodChaser | Listen Notes | Player FM | Podcast Addict | Podcast Republic | **Affiliate Link
This Best of 2025 episode brings together the most impactful moments from the year - featuring highlights with Dr. William Li, Dr. Stacy Sims, Leslie Kenny, Darren Candow, Mark Sisson, and a solo episode of mine. Across metabolism, hormones, muscle, longevity and performance, these conversations reveal what actually works for midlife health. You'll hear why brown fat matters, how women should train and fuel as hormones shift, why muscle is essential for metabolic health, and how walking, sprinting and strength outperform chronic cardio. If you want a science-backed, no-nonsense snapshot of the ideas that shaped 2025 on the show, this episode connects the dots, and gives you clear, practical takeaways you can apply immediately. WHAT YOU'LL LEARN • How brown fat supports metabolism and fat loss • Why women need different training and fuelling strategies in midlife • The role of protein and creatine in muscle, energy and recovery • How autophagy supports immune and cellular health • Why walking and sprinting beat long-duration cardio for longevity Timestamps 00:00 Metabolism After 40: Fat, Food & the Real Science of Aging Well 17:53 How Women Should Fuel, Train & Recover for Hormonal Health and Longevity 30:53 Why Creatine Becomes Essential for Women's Strength, Brain & Daily Function 42:30 The Anti-Aging Pathway Most Women Haven't Heard About Yet (Spermidine) 48:39 Creatine, Cognition & Energy: A Smarter Approach to Women's Health 54:48 Walking as Medicine: Longevity, Strength & the Most Natural Form of Fitness VALUABLE RESOURCES A BIG thank you to our sponsors who make the show possible:• Ozlo Sleepbuds® – Fall asleep faster and stay asleep longer
Show Notes Episode 430: Carl's Worst Christmas Ever and Other Holiday Tales This week Host Dave Bledsoe tries some amazing eggnog some guy's brother made with lighter fluid and starts telling stories. (Again) For our annual “Jesus, is it Christmas already?” episode, we dig into the vaults of Dave's Brain to bring you lurid tales of Christmas' gone wrong in every way possible. Be they marital infidelity, public masturbation or a singularly misfortunate ornament mishap, someone is not having a happy holiday. (This is why Dave doesn't get invited to story hours at the library.) So gather your family around the fire (I mean the adult family, leave kids watching their Youtube or whatever) pour yourselves something from a bottle being passed around and get ready for stories of people having a MUCH worse Christmas than you are! Our sponsor this week is the Holiday Ornament Safety Council who remind you that decorations go on the tree, not inside you. We open with a heartwarming family gathering and close with Lord Weatherby who is freaking out. Show Theme: Hypnostate Prelude to Common Sense The Show on Twitter: https://twitter.com/TheHell_Podcast The Show on Facebook: https://www.facebook.com/whatthehellpodcast/ The Show on Youtube: https://www.youtube.com/channel/UCjxP5ywpZ-O7qu_MFkLXQUQ Our Website: www.whatthehellpodcast.com Give us your money on Patreon https://www.patreon.com/Whatthehellpodcast The Show Line: 347 687 9601 Closing Music:https://youtu.be/T7OBPvc9ddA?si=dtGOwiq-8t-HRzSz We are a proud member of the Seltzer Kings Podcast Network! http://seltzerkings.com/ Citations Needed: 18 Christmas Disasters That'll Make You Feel Bad For Laughing https://www.buzzfeed.com/beckybarnicoat/christmas-disasters People Tell Us Their Worst Christmas Horror Stories https://www.vice.com/en/article/jgmm5p/people-tell-us-their-worst-christmas-horror-stories 24 Christmas disasters to make you feel better about burning the turkey, from poisoned guests to 7,000 acres of fire damage https://www.countrylife.co.uk/food-drink/24-christmas-disasters-make-feel-better-burning-turkey-poisoned-guests-7000-acres-fire-damage-209545 Learn more about your ad choices. Visit podcastchoices.com/adchoices
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The SKATCAST Network presents:The Brotherly Brain Cell #84Today's Game:This week Shaiden and Will once again tackle Enshrouded! Thank you for listening! Happy Monday!Visit us for more episodes of SKATCAST and other shows like SKATCAST presents The Dave & Angus Show plus BONUS material at https://www.skatcast.com Watch select shows and shorts on YouTube: bit.ly/34kxCneJoin the conversation on Discord! https://discord.gg/XKxhHYwu9zFor all show related questions: info@skatcast.comPlease rate and subscribe on iTunes and elsewhere and follow SKATCAST on social media!! Instagram: @theescriptkeeper Facebook: https://www.facebook.com/scriptkeepersATWanna become a Patron? Click here: https://www.patreon.com/SkatcastSign up through Patreon and you'll get Exclusive Content, Behind The Scenes video, special downloads and more! Prefer to make a donation instead? You can do that through our PayPal: https://paypal.me/skatcastpodcast Hosted on Acast. See acast.com/privacy for more information.
Our brain constructs the world we hear, see, and feel — but tinnitus shows how that superpower can backfire. This episode is made in collaboration with Vox's Unexplainable. Hear their series on sound here. This episode was produced by Avishay Artsy, edited by Jenny Lawton, fact-checked by Melissa Hirsch, engineered by David Tatasciore, and hosted by Jonquilyn Hill. Photo by Astrid Stawiarz/Getty Images for the Hearing Health Foundation. If you have a question, give us a call on 1-800-618-8545 or send us a note here. Listen to Explain It to Me ad-free by becoming a Vox Member: vox.com/members. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Our brain constructs the world we hear, see, and feel — but tinnitus shows how that superpower can backfire. This episode is made in collaboration with Vox's Unexplainable. Hear their series on sound here. This episode was produced by Avishay Artsy, edited by Jenny Lawton, fact-checked by Melissa Hirsch, engineered by David Tatasciore, and hosted by Jonquilyn Hill. Photo by Astrid Stawiarz/Getty Images for the Hearing Health Foundation. If you have a question, give us a call on 1-800-618-8545 or send us a note here. Listen to Explain It to Me ad-free by becoming a Vox Member: vox.com/members. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Try LMNT and get a FREE gift: https://partners.drinklmnt.com/free-gift-with-purchase?rfsn=5182916.370beb&utm_medium=sponsor&utm_source=daveasprey&utm_campaign=agwp&utm_content=podcast&utm_term=&rfsn_cn=EXCLUSIVE+GIFT+FOR+DAVE+ASPREY%27S+COMMUNITYIn this video, Dave Asprey exposes the hidden reason why people lose muscle tone and mental sharpness as early as their 30s… and reveals the simplest, cheapest powder to reverse the process.Dave walks the viewer through how this powder can directly protect the brain by replenishing cellular energy, restoring ATP production, improving memory, supporting resilience to stress and sleep loss, and slowing age-related decline. He details why most people fail to feel its benefits, the correct science-based dosing protocol, how to avoid stomach issues, and why women need it even more than men. *** Dave's Biohacking Holiday Gift Guide | Go to https://daveasprey.com/giftguide/ to explore the full guide. ***Thank you to our sponsors! • AquaTru | Go to https://aquatruwater.com/daveasprey and save $100 on all AquaTru water purifiers.• BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle.Timestamps00:00 – The Hidden Sleep Switch Nobody Talks About01:35 – The Root Causes of Bad Sleep02:13 – The Invisible Force Ruining Your Sleep03:48 – The Worst Sleeping Positions (and Why)04:30 – Correct Setup for Side and Back Sleepers06:23 – Why Food Timing Destroys Deep Sleep08:29 – The 3-Hour Rule09:33 – The Circadian Rhythm Problem in Modern Life11:30 – The Brain's Master Clock12:30 – Mimicking Nature with Morning and Evening Light14:20 – Proof That Light Manipulation Works15:05 – How to Reset Your Circadian Rhythm Step-by-StepResources: • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Connect with Dave Asprey!Website: https://daveasprey.comTikTok: https://www.tiktok.com/@daveaspreyofficialInstagram: https://www.instagram.com/dave.asprey/Facebook: https://www.facebook.com/Daveaspreyofficial/X: https://x.com/daveaspreyYouTube: https://www.youtube.com/c/daveaspreybprThe Human Upgrade Podcast: Instagram: https://www.instagram.com/TheHumanUpgradePodcast/ Facebook: https://m.facebook.com/Thehumanupgrade/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Loneliness during holidays gets weaponized by shame in highly sensitive people, turning togetherness expectations into daggers stabbing at your worth. That fullness of isolation doesn't mean you're alone - billions are yearning for connection just like you. The dangerous pattern happens when loneliness runs to your head and creates cutting stories: "You must be the only person alone on Christmas." Society has zero positive templates for loners, confusing solitude with dysfunction. The shift requires forcefully changing gears - actively looking for places you fit instead of cataloging everywhere you don't. Real connection might be two actions away. Affiliates and Sponsors: Brain FM Resources: PATTERNSCAPES DECK: https://getpatternscapes.com/ WORK WITH NIKKI 1:1: EmotionalBadass.com/coaching 30 Days to Peace Course EmotionalBadass.com/peace THE BI-WEEKLY WELLNESS NEWSLETTER EmotionalBadass.com/newsletter SUPPORT US ON PATREON Patreon.com/emotionalbadass Learn more about your ad choices. Visit megaphone.fm/adchoices
Rosie sits down with psychiatrist Dr. Tracey Marks to unpack how our “factory settings” for stress get shaped by childhood, technology, and modern life — and how anxiety and burnout show up in our bodies and brains. Together, they explore practical tools like micro-transitions, physiological sighs, and sleep rituals to help you reset your nervous system and build real resilience. You can learn more about Dr. Tracey Marks at MarksPsychiatry.com, and follow on YouTube and Instagram. Learn more about your ad choices. Visit podcastchoices.com/adchoices
In this conversation, Sathiya shares his transformative journey from being addicted to pornography to becoming a successful entrepreneur and family man. He emphasizes the importance of internal freedom, the impact of pornography on the brain, and practical strategies for achieving personal growth. Through affirmations and understanding the concept of freedom, Sathiya inspires listeners to take control of their lives and make meaningful changes. Know more about Sathiya's work: Join Deep Clean Inner Circle - The Brotherhood You Neeed (+ get coached by Sathiya) For Less Than $2/day Submit Your Questions (Anonymously) To Be Answered On The Podcast Get A Free Copy of The Last Relapse, Your Blueprint For Recovery Watch Sathiya on Youtube For More Content Like This Chapters: (00:00) From Struggles to Success: Sathiya's Journey (02:22) The Power of Change: Transforming Lives (04:50) Understanding Freedom: The Three Arenas (07:48) The Battle for Internal Freedom (10:22) The Impact of Pornography on the Brain (18:44) Solutions for Internal Freedom (26:49) Affirmations and Mindset: Shaping Your Reality
This episode Brain and Nez head to The Bay Area to listen to some FREAKY TALES. An NBA star, a corrupt cop, a female rap duo, teenage punks, neo-Nazis and a debt collector embark on a collision course in 1987 Oakland, Calif. Join the THR Presents: Stream Fiends Facebook Group. https://www.facebook.com/groups/3860579827402429 Follow THR Stream Fiends on IG: @thrstreamfiends Join The Horror Returns Facebook group: https://www.facebook.com/groups/1056143707851246 THR Patreon: https://www.patreon.com/thehorrorreturns Check out everything Horror Returns at: https://thehorrorreturns.com Join The Action Returns Facebook group. https://www.facebook.com/groups/841619946357776 Follow The Action Returns on IG and Twitter: Instagram: @theactionreturns Twitter: @action_returns Hit up E Society on Facebook. https://www.facebook.com/ESocietyPodcast/ Check out our ESP Spotify For Creators feed: https://podcasters.spotify.com/pod/show/esoc E Society YouTube: https://www.youtube.com/channel/UCliC6x_a7p3kTV_0LC4S10A E Society and Mac-Nez t-shirts Tee Public: http://tee.pub/lic/9ko9r4p5uvE X: E Society Podcast - https://x.com/esocietypod Mac Nez Podcast - https://x.com/macnezpod The Zissiou - https://x.com/TheoZissou Instagram - E Society - https://www.instagram.com/esocietypod/ Mac Nez Podcast - https://www.instagram.com/macnez/ The Zissiou - https://www.instagram.com/thezissou/ TikTok - https://www.tiktok.com/@esocietypod Intro Music by Mixla Beats Productions https://www.mixlaproduction.com
In this Season 14 review (Part 3) Andrea revisits key insights from Dr. Shane Creado on the critical link between sleep, concussions and performance. The episode explains how even mild or repeated head impacts and sleep deprivation damage the same brain regions that support learning, memory, decision-making and emotional regulation, and how one all‑nighter can reduce hippocampal learning capacity by around 40%. Practical takeaways include treating sleep as neurological recovery (7–9 hours), protecting the brain after head jolts, avoiding late alcohol and screens, and prioritizing consistent sleep routines to restore learning, resilience and long‑term brain health for athletes, students and professionals. Welcome back to SEASON 14 of The Neuroscience Meets Social and Emotional Learning Podcast, where we connect the science-based evidence behind social and emotional learning and emotional intelligence training for improved well-being, achievement, productivity and results—using what I saw as the missing link (since we weren't taught this when we were growing up in school), the application of practical neuroscience. I'm Andrea Samadi, and seven years ago, launched this podcast with a question I had never truly asked myself before: (and that is) If productivity and results matter to us—and they do now more than ever—how exactly are we using our brain to make them happen? Most of us were never taught how to apply neuroscience to improve productivity, results, or well-being. About a decade ago, I became fascinated by the mind-brain-results connection—and how science can be applied to our everyday lives. That's why I've made it my mission to bring you the world's top experts—so together, we can explore the intersection of science and social-emotional learning. We'll break down complex ideas and turn them into practical strategies we can use every day for predictable, science-backed results. As we are nearing the end of Season 14 here, it has been about reflection as we have looked back and reviewed past interviews. Our goal has not been about nostalgia, or remembering these interviews, the goal has been about integrating what we have learned. Taking what we know, aligning it with how the brain actually functions, and applying it consistently enough to change outcomes. And if there's one thing this season has reinforced, it's this: Sustainable success isn't built on intensity or focus alone—it's built on alignment. As we move into what's next, (Season 15) the focus shifts from understanding this alignment to bringing this alignment into a tangible, physical form, or embodiment. Not more information—but better execution. After hundreds of conversations with neuroscientists, educators, peak performers, and thought leaders, one truth keeps resurfacing— lasting success is never about doing more. It's about alignment. Alignment between how the brain actually works, how emotions drive behavior, and how daily habits compound over time. Season 14 has been about stepping back—not to reminisce, but to integrate what we have learned into our current life. I knew the minute that I was sent a couple of video clips from our past episodes, that I had forgotten about, that while I thought I had implemented the ideas from our past guests, I had some work to go myself. For this reason, we spent Season 14 and will resume with Season 15 next January, reviewing past episodes, with the goal of noticing what we have now aligned, that's bringing us results in our daily life. Core Reflection When we started this podcast 7 years ago, the goal was simple: bridge neuroscience research with practical strategies people could actually use. What I didn't fully appreciate then—what only became clear through repetition, reflection, and real-life application—is that information alone doesn't create change. Understanding the brain doesn't matter if we ignore what to do with the information we release each week: improving our sleep reducing our stress practicing emotional regulation with consistency that actually changes who we are at the core: our identity Season 14 has been about connecting those dots. Listening again to conversations with voices like Dr. John Medina, Dawson Church, Bob Proctor, Dr. John Ratey, Friederike Fabritius, and so many others, one pattern became impossible to ignore: The brain thrives on simplicity, repetition, and finding emotional safety to implement these concepts—not intensity or a quick fix. We will take the time with each interview review to offer ways for all of us to implement the lessons learned, so that when we finish 2026, we will be able to look back, and see where our changes all began. This week, we move onto PART 3 of our review of EP 72[i] with Shane Creado, MD and his book Peak Sleep Performance for Athletes recorded back in July of 2020. ✔ In PART 1[ii], we covered: How strategic napping, morning brain habits, and even the Silva Method all work together to reset your brain, boost performance, and transform your health from the inside out. ✔ In PART 2[iii] we continued with our review, diving a bit deeper into sleep deprivation and its impact of performance (whether you are an athlete, or just someone looking to improve productivity). ✔ PART 3, we will go a bit deeper into the impacts of concussions and brain injuries on our sleep and performance. Let's go back to 2020 and revisit what Dr. Creado had to say about sleep in this last episode of this season. VIDEO 1 – Click Here to Watch In the first clip of this episode, with Dr. Creado, he dives into the connection with concussions and sleep. He says, “Most people who have had a concussion end up with sleep problems. It makes a lot of sense when you think about the brain and how it regulates sleep and wakeful cycles and then it gets jarred. But what people don't realize is that even a mild head injury can really damage your brain. Even if you're not officially diagnosed with a concussion, you don't have to lose consciousness to have a concussion. You don't even need to have any symptoms to have your brain injured in some way. And then the little injuries along the way add up over time. So the brain is as soft as butter and in a hard, bony skull. Anything that jars it, even whiplash can cause your brain to be injured. And it accumulates over time. What's interesting is that the same regions of the brain that are most damaged in head injuries are also damaged in sleep deprivation and also alcohol use. The frontal lobes, the temporal lobes and the parietal lobes at the top of the brain.”
If going home for the holidays leaves you anxious, exhausted, or feeling like you're twelve years old again, this is not emotional weakness. This is your nervous system.When you're around your family of origin, the oldest wiring in your brain comes back online. These patterns were built before you had adult self-regulation. Your limbic system reacts fast, old roles resurface, and your regulated adult self can get pushed offline without you realizing it.What you're experiencing is neurological conditioning, not failure. And this season is an opportunity to do something different. You can interrupt the hijack, respond instead of react, and stay grounded even when everyone around you is not.Family of Origin Dysfunction: Why Going Home Dysregulates Your Brain
Today's conversation is the return of our round table discussion with Chris Burns, owner of Savage Scholar Consulting and David Hatt, Founder of MTN. This time round, we each share our 3 biggest lessons in Brain, Body and Business to arm you with the tools for success going into 2026.Today's episode is optimised by Puresport. You can save 10% using code CAMBRO10 – https://bit.ly/3RmVT0V Shop Notox Skincare using COL15 here - https://www.notoxskincare.co/ Get my LinkedIn Guide - https://click.convertkit-mail2.com/qdux4r4dq8u7h4dxgxvalh89p0rkkb4h86ng9/08hwh9h22xp4z6tl/aHR0cHM6Ly9jb2xjYW1icm8ua2l0LmNvbS9wcm9kdWN0cy9saW5rZWQtaW4tcGVyc29uYWwtYnJhbmQtZm9yLXNlbGxpbmc=Free 20 lessons from 330 CamBro Conversations - https://colcambro.kit.com/60ed1b527b Connect with Col:Instagram: https://www.instagram.com/col.cambro/Email List - https://colcambro.kit.com/30bde23b0cJoin patreon - patreon.com/ColCampbellConnect with Chris:Instagram - https://www.instagram.com/storyseller_chris/Email - chris@thesavagescholar.comConnect with David:Instagram - https://www.instagram.com/dhatt_mtn/MTN Coaching - http://mtncoaching.co.uk/
They found something strange inside a skull buried in Pompeii — a glossy, black chunk no one could explain. For years, it sat unidentified. But now, scientists have finally confirmed the impossible: it's a human brain turned to glass. How could something so fragile survive a volcanic eruption? What does this reveal about the terrifying heat of Mount Vesuvius? And could there be more discoveries like this, still hidden in the ashes? This isn't just a bizarre scientific first — it's a glimpse into a moment frozen in fire. Learn more about your ad choices. Visit megaphone.fm/adchoices
Kathryn and Coach Julie explore how gentle humor can support recovery—without minimizing the seriousness of binge eating or eating disorders. You'll learn how bringing some laughter into certain situations can help pull you out of fight-or-flight and harsh self-criticism, so you can make clearer, more grounded choices. You'll also learn how humor can soften perfectionism, and change the way you relate to urges so that you can more easily dismiss them. Coach Julie's new website: https://juliemanncoaching.com/ Join Coach Julie's email list Brain over Binge resources: Get the FREE 30-day Inspiration Booklet Get personalized support with one-on-one coaching or group coaching Subscribe to the Brain over Binge Course for only $18.99 per month Get the Second Edition of Brain over Binge on Amazon and Audible, BarnesandNoble.com, Apple iBooks, or Kobo. Get the Brain over Binge Recovery Guide Disclaimer: *The Brain over Binge Podcast is produced and recorded by Brain over Binge Recovery Coaching, LLC. All work is copyrighted by Brain over Binge Recovery Coaching, LLC, and all rights are reserved. As a disclaimer, the hosts of the Brain over Binge Podcast are not professional counselors or licensed healthcare providers, and this podcast is not a substitute for medical advice or any form of professional therapy. Eating disorders can have serious health consequences and you are strongly advised to seek medical attention for matters relating to your health. Please get help when you need it, and good luck on your journey.
9 Brain Exercises to Strengthen Your Mind | Must Listen for Self Improvement | 2026Get AudioBooks for FreeBest Self-improvement MotivationGet AudioBooks for FreeWe Need Your Love & Support ❤️https://buymeacoffee.com/myinspiration#Motivational_Speech#motivation #inspirational_quotes #motivationalspeech Get AudioBooks for Free Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
This episode covers: • FDA Loosens Supplement Warning Labels The FDA is considering a rule change that would allow supplement companies to include the DSHEA disclaimer only once per package rather than next to every claim. Dave explains why fewer visible warnings could make marketing look more like medical claims, and why biohackers should treat labels as advertising rather than evidence. He shares how to protect yourself now: add one variable at a time, run baseline labs, and rely on data instead of packaging. Source: https://www.nbcnews.com/health/health-news/fda-supplements-warning-label-rule-change-rfk-jr-rcna249321 • Quantum Sensors for Early Heart Attack Detection Mayo Clinic is testing a contactless heart-monitoring system called CardiAQ using quantum magnetic sensors and AI noise filtering. The device reads subtle electromagnetic signatures from the heart and compares them to invasive angiography. Dave breaks down why earlier detection of ischemia could shift heart care from reactive treatment to proactive screening — and why building baseline metrics like VO₂max, blood pressure and HRV today will pay off when next-gen diagnostics arrive. Source: https://www.sandboxaq.com/press/sandboxaq-collaborates-with-mayo-clinic-on-novel-cardiac-diagnostics • Sauna Detox for MicroplasticsEmerging research shows that sweating meaningfully removes plastic-related chemicals like BPA and phthalate metabolites from the body, often more efficiently than blood or urine alone. Sauna use amplifies this effect by increasing circulation, mobilizing stored toxins from tissues, and accelerating sweat-based excretion. When you combine regular heat exposure with reduced environmental plastic contact, you create a powerful detox strategy that targets a chemical burden once thought unavoidable. Dave breaks down how sauna protocols can support toxin elimination, improve cardiovascular resilience, strengthen autonomic balance, and help counteract the metabolic and hormonal disruptions linked to microplastics in modern life.Source: https://superage.com/can-you-sweat-out-microplastics-in-the-sauna/ • Psychedelics and Longevity Biomarkers Bryan Johnson treated a guided psilocybin experience as a structured longevity experiment, collecting nearly 250 biomarkers including CGM, stress markers, HRV and Kernel brain imaging. The experiment revealed a surprising metabolic change: mean glucose dropped 8 percent, variability fell 11 percent, and estimated HbA1c moved from 4.7 to 4.4 — similar to months of metformin but after a single session. Dave explores the emerging idea that neuroplastic events might influence glucose regulation through brain-pancreas signaling, while emphasizing the need for supervised, legal use and proper clinical trials. Source: https://www.businessinsider.com/bryan-johnson-trip-on-mushrooms-five-hours-live-2025-12 • A Mitochondrial Protein that Extends Mouse Lifespan Researchers boosted the mitochondrial protein COX7RP and extended mouse lifespan by ~6.6 percent while improving insulin sensitivity, lipid handling, endurance and liver fat metabolism. COX7RP supports formation of mitochondrial “supercomplexes,” improving respiratory efficiency and ATP generation. Dave explains how this reinforces lifestyle levers — strength training, aerobic capacity, stabilizing blood sugar — as tools that likely preserve supercomplex architecture and mitochondrial resilience. Source: https://www.eurekalert.org/news-releases/1109082 All source links provided for direct access to the original research and reporting. This episode is designed for biohackers, longevity seekers and high-performance listeners who want practical strategies rooted in cutting-edge science. Dave Asprey translates emerging research into actionable upgrades for your biology — from metabolism and mitochondria to nervous system health, detox, and prevention. New episodes every Tuesday, Thursday, Friday, and Sunday. Keywords: FDA supplement rule change, supplement warning labels, DSHEA disclaimer removal, supplement regulation risks, quantum cardiac scanner, Mayo Clinic heart attack detection, AI heart monitoring, early ischemia detection technology, sauna detox evidence, sweating out toxins research, BPA phthalate sweat studies, microplastics sauna myth, Bryan Johnson psilocybin experiment, psychedelic longevity research, psychedelic metabolic reset, glucose control psychedelics, HbA1c psilocybin results, continuous glucose monitor insights, mitochondria lifespan research, COX7RP protein aging study, mitochondrial supercomplex benefits, ATP energy output aging, metabolic flexibility longevity, biohacking news update, anti-aging science breakthroughs, evidence-based longevity tools, biological age biomarkers Thank you to our sponsors! -BEYOND Conference 2026 | Register now at https://beyondconference.com/ -BodyGuardz | Visit https://www.bodyguardz.com/ and use code DAVE for 25% off. Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Intro 0:18 - Story 1: FDA Supplement Label Changes 1:43 - Story 2: CardiAQ Heart Scanner 2:59 - Story 3: Saunas and Microplastics 4:58 - Story 4: Psychedelics and Blood Sugar 8:22 - Story 5: Mitochondrial Longevity Research 10:29 - Weekly Wrap-Up See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
After a terrifying car accident left her with concussion syndrome, Dr. Leila Doolittle was determined to learn how to heal her brain naturally and devoted her life to helping others heal from the chronic symptoms of bodily trauma. Dr. Motley met up with her at the Changing Life + Destiny Conference to discuss powerful underrated tools to help the brain and body heal from injury, mold toxicity and more. Things like: Herbal Remedies Bioenergetic Medicine Nervous System Balance (trusting in your worthiness) And the Healing Power of the Mind Recommendations for Brain Injury: Lion's Mane Vitamin A, E, C Resveratrol (found in red grapes, blackberries and peanuts) can restore the blood-brain barrier. Chinese Coptis: https://shorturl.at/TzXGI Ginseng Want more of the Ancient Health Podcast? Check out Doctor Motley's YouTube channel! ------ Follow Doctor Motley Instagram TikTok Facebook Website Follow Dr. Leila www.drleiladoolittle.com https://www.instagram.com/drleiladoolittle/?hl=en ------ *Sign up for Doctor Motley's newsletter for more TCM tips, frequency medicine pearls of wisdom and his takes on vital health topics: https://www.doctormotley.com/ * Do you have a ton more in-depth questions for Doctor Motley? Are you a health coach looking for more valuable resources and wisdom? Join his membership for modules full of his clinical expertise on so many health issues - including brain health - plus bring all your questions to his weekly lives! Explore it free for 15 days at https://www.doctormotley.com/15 *Most of us are mineral deficient and we don't even know it! Want to get your minerals in? BEAM Minerals is a simple shot of minerals each morning. Tastes like water, absorbs fast, and gives your body the full spectrum of minerals it needs. It's one of the easiest, most effective ways to support overall vitality. Try BEAM Minerals at beamminerals.com/DRMOTLEY and use code DRMOTLEY for 20% off your first order.
In this week's episode I am joined by Dr. Darby Saxby, a clinical psychologist and professor at the University of Southern California as we delve into the transition to parenthood, particularly focusing on fathers and the concept of the 'dad brain.' We discuss how fathers experience physiological and psychological changes despite not giving birth, the vulnerability and opportunities for growth these changes bring, and how societal structures often fail to support new parents adequately. Dr. Saxby shares insights from her research, including how caregiving impacts brain structure in both mothers and fathers and the importance of fathers being involved at various stages of a child's development. I WROTE MY FIRST BOOK! Order your copy of The Five Principles of Parenting: Your Essential Guide to Raising Good Humans Here: https://bit.ly/3rMLMsLSubscribe to my free newsletter for parenting tips delivered straight to your inbox: https://dralizapressman.substack.com/Follow me on Instagram for more:@raisinggoodhumanspodcast Sponsors:Avocado Green Mattress: With code humans, you'll save an extra $25 on Crib and Kids Mattresses on top of their holiday sale! That's an extra $25 off their current sale at AvocadoGreenMattress.com with the code humansOsea: Get 10% off your first order sitewide with code HUMANS at OSEAMalibu.comWayfair: Head to Wayfair.com right now to shop all things homeSuvie: Go to Suvie.com/Humans to get $150 off plus 16 free meals when you order during their saleLaundry Sauce: Make laundry day the best day of the week! Get 20% off your entire order @LaundrySauce with code HUMANS at https://laundrysauce.com/HUMANS #laundrysaucepodTia: Go to bit.ly/asktia-humansPlease note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode.Produced by Dear Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
An interstellar object just cruised into our cosmic neighborhood and—naturally—humanity immediately responded with calm, measured curiosity… by screaming “ALIENS!” into the void.This week on Hysteria 51, we're diving into 3I/ATLAS, the latest confirmed visitor from beyond our solar system. Is it just a dirty, fast-moving comet minding its own business? Or is it something a little more… engineered? We break down what scientists actually know so far, why this thing has the internet acting like it found a Wi-Fi signal in the Kuiper Belt, and what the “completely natural” crowd says (spoiler: they have math and spectra and other buzzkills).Then we do what we do best: lean into the fun. If 3I/ATLAS is under intelligent control—even hypothetically—what does that mean for humanity? First contact? Surveillance? A cosmic prank? Or just a high-speed reminder that we are absolutely not the main character of the universe.Strap in, stare into the sky suspiciously, and remember: “closest approach” doesn't mean “close,” but it does mean the conspiracy machine is about to hit maximum RPM this week on Hysteria 51!Special thanks to this week's research sources:YouTube (video): 3I/ATLAS Is Causing Scientists To Panic. Here's Why. YouTube. YouTubeNASA Science: NASA. (n.d.). Comet 3I/ATLAS (mission/observation timeline page). NASA Science. NASA ScienceMinor Planet Center (MPEC): Minor Planet Center. (2025, Jul 2). MPEC 2025-N12: 3I/ATLAS = C/2025 N1 (ATLAS). Minor Planet CenterarXiv (early discovery & characterization): Discovery and Preliminary Characterization of a Third Interstellar Object: 3I/ATLAS. arXiv:2507.02757. (2025). arXivMNRAS (SOAR photometry): Frincke, T. T., et al. (2026). Near-discovery SOAR photometry of the third interstellar object: 3I/ATLAS. Monthly Notices of the Royal Astronomical Society (Advance Article). OUP AcademicMNRAS Letters (spectrum paper): Opitom, C., Snodgrass, C., Jehin, E., et al. (2025, Nov). Snapshot of a new interstellar comet: 3I/ATLAS has a red and featureless spectrum. MNRAS: Letters, 544(1), L31–L36. OUP AcademicA&A (context vs other comets/interstellars): de la Fuente Marcos, R., et al. (2025). Assessing interstellar comet 3I/ATLAS with the 10.4 m Gran Telescopio Canarias… Astronomy & Astrophysics. A&A Scientific JournalarXiv (technological hypothesis paper): Hibberd, A., Crowl, A., & Loeb, A. (2025, Jul 16). Is the Interstellar Object 3I/ATLAS Alien Technology? arXiv:2507.12213. arXivJason Wright (rebuttal / anomaly breakdown): Wright, J. (2025, Nov 9). Loeb's 3I/ATLAS “Anomalies” Explained. AstroWright (Penn State). Penn State SitesSecondary roundup referencing rebuttal: ScienceAlert. (2025, Nov 13). Don't Panic! 3I/ATLAS Isn't an Alien Death Probe, But It Is Wildly Unusual. ScienceAlertEmail us your favorite WEIRD news stories:weird@hysteria51.comSupport the ShowGet exclusive content & perks as well as an ad and sponsor free experience at https://www.patreon.com/Hysteria51 from just $1ShopBe the Best Dressed at your Cult Meeting!https://www.teepublic.com/stores/hysteria51?ref_id=9022See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Ever wake up with that “today is the day” feeling, like you are ready to conquer the world? The guys start there, take a hard left into Pinky and the Brain, and somehow end up pondering what it was like when Christ rose from the dead. From there, it turns into a practical, tradition-packed episode on celebrating Christmas well. Not the Hallmark version, and not the American “Christmas ends on December 26” version either. The kind that actually follows the liturgical calendar, keeps Advent as Advent, and treats Christmas as a season, not a day.Along the way, they review a Taiwanese whiskey from the Scotch Malt Whisky Society, talk family customs that make the day feel grounded, and make a strong case for grandfathers and fathers to be the custodians of tradition. One of the best parts is a simple, doable challenge: take the 12 Days of Christmas seriously and mark the feast days with small, intentional practices your family will actually remember.In this episode:The “wake up and conquer the world” mood vs the day Christ resurrectedAdvent vs Christmas, and why our culture gets it backwardsWhy “Merry” used to mean more like blessed than happyMidnight Mass, caroling, real Christmas trees, and reading Luke before presentsA great grandfather tradition: gather the family and speak from the heartGifts for kids: fewer and meaningful vs abundance as a sign of the Father's generosityThe 12 Days of Christmas, and the feast days that stack up fastSt. John's Blessing of Wine and why you should do itA practical idea for the Holy Innocents: dads blessing their children out loudEpiphany water and why you should plan ahead to get it blessedWhiskey for the episode: Taiwanese whiskey (Scotch Malt Whisky Society pick), “Dunker's Delight” style notes, 107 proof, with flavors like caramel and apple pie crust.Challenge for the week: Pick two feast days during the 12 Days of Christmas and do something small but real. Bless your kids, bless wine, invite someone over, go to Mass, or start a tradition worth keeping.
Get this whole, show FREE on Patreon! Click HERE for a 7-day free trialBen Glaze and EZ lean into fair-use laws to present a WEEKLY review of one of America's top radio shows. Heard all across the US on about 30 radio stations, The Free Beer and Hot Wings Show has grown steadily since it's inception in the late 1990's.In this FULL show on Patreon!Topics:*Who knew that eating buttered bread could be so hilarious? It must be, based on Hot Wings chuckles during his story about it.*Hot Wings keeps the laughs rolling when describing Christmas ornaments.*Maitland and Kelly couldn't sound dumber with their questions about male genital position when sitting on the toilet.*Ben has a ton of clips of Free Beer letting us know that "he's just kidding."*No FB on a recent show, so the gang got to really focus on the things they want to talk about, rather than Free Beer's usually awesome story selection. So they opened up a show by taking a "deep dive" into how to package food in "to-go boxes."*Ben updates Steve's, "69 Supercut."*Free Beer's brain breaks.*More Free Beer "Brain-tumor talk."*The gang breaks down Scotch tape and wrapping paper.Our Sponsors:* Check out Secret Nature and use my code ZANE for a great deal: https://secretnature.comSupport this podcast at — https://redcircle.com/the-eric-zane-show-podcast/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
World's leading neuroscientists Dr Tara Swart explains why so many high-functioning people feel exhausted, stressed, and out of balance, even when they're doing everything “right.” She breaks down the hidden cost of being constantly switched on, how chronic stress rewires the brain, and why late-night scrolling is quietly sabotaging your energy, focus, and health.Dr Tara also reveals how stress can drive weight gain, particularly around the belly, and why modern lifestyles keep the brain stuck in survival mode. From simple micro-habits that move you from fear to joy, to the science behind nature, attention, and human connection, this episode offers practical, science-backed ways to feel calmer, healthier, and more present, starting with just a few minutes a day. Hosted on Acast. See acast.com/privacy for more information.
In this Huberman Lab Essentials episode, I explain how to use science-based tools to better set and achieve goals. I discuss the neuroscience of goal pursuit and how dopamine and visual attention shape motivation and effort. I explain whether visualizing success or failure better supports goal pursuit, how to choose goals at the right level of difficulty and evaluate progress. I also share a short “space-time bridging” protocol that helps train long-range, goal-directed behavior. These tools will help you stay motivated and reach goals more effectively. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps (00:00:00) Goal Setting (00:00:23) Brain & Goal Pursuit (00:03:32) Goal Value, Action Steps (00:05:49) Sponsor: David (00:07:07) Peripersonal vs Extrapersonal Space (00:08:34) Tool: Visual Focus & Pursuing Goals (00:13:04) Visualization & Goal Pursuit, Tool: Visualize Failure (00:15:25) Sponsor: AG1 (00:16:48) Tool: Goal Setting & Difficulty Level (00:18:27) Dopamine & Goal Pursuit, Reward Prediction Error, Tool: Weekly Goal Assessment (00:23:39) Dopamine & Vision; Importance of Behavioral Tools (00:25:37) Recap of Tools for Goal Setting & Pursuit (00:26:49) Sponsor: LMNT (00:28:21) Goal Pursuit, Time; Tool: Space-Time Bridging (00:35:49) Recap, Key Takeaways Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices
Why do you keep saying you'll start tomorrow but never do? In this episode, I explain why it's not laziness holding you back and how to rewire your brain so you can finally take disciplined action, even when it's uncomfortable. If you want 2026 to be your best year yet then this video is for you. In just 30 minutes, I'll help you build a clear, simple goal system so you stop guessing and start moving forward with confidence.
This episode explores how intimacy, desire, and erotic states function as powerful tools for healing, nervous system regulation, and personal transformation. You'll learn why certain forms of conscious erotic play create genuine altered states of consciousness, not through substances or external compounds, but through the body's own internal chemistry. This conversation reframes sexuality as a core aspect of health, performance, and emotional resilience rather than something separate from personal development or spirituality. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Kimi Inch is a somatic therapist and educator with over 20 years of experience working at the intersection of intimacy, conscious kink, trauma healing, and embodied self awareness. Her work centers on helping individuals and couples access deep states of connection and healing through structured, consent based practices that engage breath, sensation, power dynamics, and presence. She is known for creating safe, grounded spaces where people can explore desire in ways that support lasting nervous system regulation and authentic self expression. Together, Dave Asprey and Kimi explore how erotic experiences trigger specific neurochemical responses including oxytocin, serotonin, endorphins, and adrenaline, and why this internal cocktail mirrors the effects of many psychedelic and somatic healing modalities. They discuss surrender, safety, attunement, and aftercare as essential components of integration, and why unexpressed desire often leaks into leadership, relationships, and performance in destructive ways. You'll Learn: • How erotic states create real altered states of consciousness through internal neurochemistry • Why intimacy can function as a powerful form of nervous system regulation and trauma healing • The difference between conscious desire and compulsive behavior • How surrender, safety, and attunement reshape emotional and relational patterns • Why suppressed desire leaks into work, leadership, and relationships • What makes healthy power dynamics healing rather than harmful • The role of aftercare and integration in long term transformation • How erotic intelligence connects to vitality, authenticity, and human performance Thank you to our sponsors! -EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off. -Calroy | Head to https://calroy.com/dave for an exclusive discount. -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: conscious kink, erotic healing, intimacy and healing, altered states of consciousness, somatic therapy, nervous system safety, erotic intelligence, surrender and intimacy, power dynamics psychology, trauma and embodiment, aftercare and integration, neurochemistry of intimacy, oxytocin bonding, endorphins and pleasure, consent based intimacy, asking for what you want, suppressed desire, authenticity and intimacy, biohacking intimacy, Dave Asprey intimacy, Kimi Inch Biohack Resources: • Kimi's Website: https://andmorepresents.com/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 - Trailer 1:25 - Altered States Through Kink 4:41 - Learning to Receive 12:17 - Play Parties Explained 19:31 - Life Force Energy 26:40 - Desire vs Compulsion 28:23 - The Kidnapping Session 35:53 - Aftercare and Integration 45:35 - Bedroom = Life 52:50 - CEOs and Surrender See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.