Podcasts about neuropsychiatric genetics

This episode of Books and Ideas is an interview with David Shariatmadari author of "Don't Believe a Word: The Surprising Truth About Language." We explore some of the common myths about language. This includes a follow up of our recent discussion on Brain Science about the evidence against the assumption that language is an instinctive. Links and References: Don't Believe a Word: The Surprising Truth About Language by David Shariatmadari Cognitive Gadgets: The Cultural Evolution of Thinking by Cecilia Heyes Interviewed in Brain Science 168 Pullum, GK and Schultz, BC, (2002) Empirical assessment of stimulus of poverty arguments. The Linguistic Review, 19, ?. Hsu, H J, and Bishop, DV (2014) Sequence-specific procedural learning deficits in children with specific language impairment. Developmental Science,17(3), 352-365. Tomblin, J B, Shribirg, L , Murray, J, Patil, S, and Williams, C. (2004). Speech and Language characteristics associated with a 7/13 translocation involving FOXP2. American Journal of Medical Genetics, Part B, Neuropsychiatric Genetics, 130, 97-?. Both books have extensive references. For more please see show notes of BS 168. Announcements: Coming in early May 2020: new expanded edition of re You Sure? The Unconscious Origins of Certainty by Virginia "Ginger" Campbell, MD. Sign up for Brain Science Newsletter for updates. Send email to docartemis@gmail.com or post voice feedback at http://speakpipe.com/docartemis. Books and Ideas is going on hiatus until November 2020 so that Dr. Campbell can work on her neuroscience writing project. Please subscribe in your favorite podcasting app so that you don't miss the next episode. Connect on Social Media: Twitter: @docartemis Facebook page: http://www.facebook.com/booksandideas

Postnatal depression refers to a depressive illness following childbirth and may form part of a unipolar or, less frequently, a bipolar illness. Ian Jones, Professor of Psychiatry, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, gives us an overview of the condition. For more on postnatal depression, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/512 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Dr. Holmans is head of the Biostatistics and Bioinformatics Unit at the MRC Centre for Neuropsychiatric Genetics and Genomics at Cardiff University, and has over 25 years' experience in the statistical analysis of complex genetic traits, both in data analysis and developing novel genetic methodology. He has led the statistical analysis of large multicentre collaborations in genome-wide linkage of schizophrenia, and association in Alzheimer’s disease and schizophrenia. Of particular relevance to HD and other repeat disorders, he led the pathway analysis of the two GeM genetic modifiers GWAS (2015, 2019) and also the genetic analysis of HD progression (Hensman-Moss et al. 2017b), implicating DNA repair pathways as modifiers both of age at onset and progression in HD. He has also led the pathway analyses of HD RNA-seq expression data in myeloid cells (Miller et al. 2016) and whole blood (Hensman-Moss et al. 2017a), implicating immune pathways as relevant to HD pathogenesis and uncovering shared susceptibility pathways with other neurodegenerative disorders. Currently, he is interested in discovering genetic modifiers associated with other phenotypes (particularly psychiatric) in HD. Dr. Holmans is married to Lesley Jones and they live in Cardiff with three cats He is a keen bridge player, fond of watching cricket and also a die-hard St Louis Cardinals fan.

We’re delighted to be joined by Dr Sophie Legge and Dr Antonio Pardiñas for our latest minisode to discuss their latest research study.Sophie, Antonio and colleagues at Cardiff University’s MRC Centre for Neuropsychiatric Genetics and Genomics examined genetic data from more than 500 people of African descent taking clozapine, an anti-psychotic medication prescribed to people with treatment resistant schizophrenia.Clozapine is currently the most effective treatment for people with treatment-resistant schizophrenia, but it can cause a rare side effect called neutropenia. In the most extreme cases, this can develop into agranulocytosis; a severe and potentially life-threatening condition.These side-effects are characterised by lower neutrophil levels, a type of white blood cell, and these lower levels appear to be more common in people of African descent. The team were interested in learning whether genetic factors were at play, and in this minisode Sophie and Antonio explain what they found and how their results could help improve the management of clozapine treatment.For links and resources mentioned in this episode, visit https://www.ncmh.info/podcastWe hope you enjoy and we would be really grateful if you could leave us a review and help others find our podcast! If you've got any questions about this episode, get in touch at info@ncmh.info. See acast.com/privacy for privacy and opt-out information.

22q11.2 deletion syndrome, or 22q for short, is a genetic syndrome affecting between 1 in 2000 and 1 in 4000 people.There are a wide range of health issues associated with the syndrome, such as heart conditions and immune problems, palatal defects and speech delays. It can also cause developmental problems and learning disabilities, and increased risk of a range of mental health problems, including schizophrenia, ADHD and depression.To tell us more about 22q, we're joined by Professor Marianne van den Bree, a Principal Investigator at Cardiff University's MRC Centre for Neuropsychiatric Genetics and Genomics.We also get a parent perspective from Katie and Jon, whose daughter Ivy was diagnosed with 22q last year.For links and resources mentioned in this episode, visit www.ncmh.info/videos-and-podcast…deletion-syndrome/We hope you enjoy, and if you have any feedback please get in touch at info@ncmh.info See acast.com/privacy for privacy and opt-out information.

It's International Women's Day, and to mark the event we are celebrating women in science. In this minisode, our guest host Catrin Hopkins, is joined by three scientists - Dr Adele Pryce-Roberts, Jasmine Donaldson and Rachel Pass. Adele is an Alzheimer's UK Clinical Research Fellow at the MRC Centre for Neuropsychiatric Genetics and Genomics, where Jasmine is doing her PhD in the area of Huntington's disease. Rachel is also a PhD student, based at Cardiff University's Neuroscience and Mental Health Research Institute, where she is investigating copy number variants and schizophrenia.We hope you enjoy, and if you have any feedback please get in touch at info@ncmh.info See acast.com/privacy for privacy and opt-out information.

ADHD remains one of the most stigmatised mental health problems. In this episode, we're speaking to Zoe Piper, founder of ADHD Connections, about her experiences.We're also joined by Professor Anita Thapar CBE, Director of the neurodevelopmental disorders research at Cardiff University's MRC Centre for Neuropsychiatric Genetics and Genomics, to discuss the latest research in this area.For links and resources mentioned in this episode, visit www.ncmh.info/videos-and-podcasts/podcast/adhd/We hope you enjoy, and if you have any feedback please get in touch at info@ncmh.info See acast.com/privacy for privacy and opt-out information.

Enhanced Audio PodcastAired date: 2/22/2010 12:00:00 PM Eastern Time

Enhanced Video PodcastAired date: 2/22/2010 12:00:00 PM Eastern Time