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On this episode, Jen and Frank answer questions from the paying guests of DillosDizResort.com as Theme Park Rob, Louis and Val, and ADAM! all sit in! *** Dillo's Diz 55 Gerard St. #987. Huntington, NY 11743 Affiliate Links Music & Themes produced by Matt Harvey. Feedspot's Top 25 Siblings Podcasts You Must Follow AND Top 100 Disney Podcasts You Must Follow. ONE STOP SHOP ALL THE @DillosDiz LINKS! DIllo's Diz Resort Guests: Theme Park Rob, Jeffers, Skipper Bob, Nathaniel Hardy, Louis and Dr. Val of #FigmentsInTime, Lee Taylor, Maz, Troy with the Disney Assembled Podcast, Judy Van Cleef, Ryan Alexander, PixieDustPhD, Jason Romans, Holly Maddock, Lexi Andrea, Adam Elmers, DCLDuo, Disney Assembled Question or Comment? We LOVE interacting with listeners! FOLLOW Dillo's Diz on INSTAGRAM: https://www.instagram.com/dillosdiz/ FOLLOW Dillo's Diz on YOUTUBE: https://www.youtube.com/dillosdiz FOLLOW Dillo's Diz on TWITTER: https://twitter.com/dillosdiz
Today on The Drive with Paul Swann: West Virginia State hires Huntington native and Huntington High alum Whitney Bays as its new women's basketball coach. Marshall alum Michael Adams of the Austin Sports Journal joins the show to break down Texas State's move to the Pac-12. Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:
On this bonus episode, I share my interview with West Virginia native Dave Nitz, recorded on May 28, 2024—just as he announced his retirement after nearly 50 years as the “Voice of the Bulldogs” at Louisiana Tech. Over a broadcasting career spanning almost 60 years, Dave called more than 4,500 Louisiana Tech games—including football, basketball (both men's and Lady Techsters), and baseball—and 36 summers of minor league baseball, culminating in his 2019 induction into the Louisiana Sports Hall of Fame. He shares candid stories from the booth, his enduring love for the game, and reflections on what's next after an extraordinary run. Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:
Can you do better than Brian in today's installment of the Two Grand Slam?
The Drive with Paul Swann for Wednesday, June 25, 2025 Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:
The Drive with Paul Swann for Tuesday, June 24, 2025 Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:
“This is us. These are our neighbors”. Mfoniso Udofia and Kevin Becerra talk with Michael Goodfriend about the process of making “runboyrun” meaningful for listeners in Boston and beyond, writing into the future, disrupting the Unities, staying present with the work, and how sometimes holding can hurt. The Huntington continues the sweeping nine-play Ufot Family Cycle and announces plans for runboyrun, the powerful drama written by Mfoniso Udofia and directed by Christopher V. Edwards. The third play in Boston's epic nine-play Ufot Family Cycle, runboyrun will be recorded and made nationally available as a podcast in partnership with the Boston Public Library, GBH, and Next Chapter Podcasts. Learn more about your ad choices. Visit podcastchoices.com/adchoices
The Drive with Paul Swann for Monday, June 23, 2025 Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:
BT and Sal dive headfirst into the chaotic world of New York sports, offering unfiltered takes on the Mets and Yankees' ongoing sagas, from bullpen woes to trade speculation. Beyond the diamond, they dissect the NBA Finals, sharing passionate, sometimes controversial, opinions on the league's biggest moments and players. And when the sports world needs a break, they pivot to lively discussions about classic and new movies, often sparking heated debates over what constitutes a cinematic "must-see" versus a "haven't seen it and don't care to" flick, much to the amusement (or frustration) of their callers. Here's a breakdown of the conversation with timestamps: 0:00:00 - 0:02:15: Discussions about the movie Braveheart and Sal not having seen it. 0:02:15 - 0:05:05: Sal's movie-watching habits, not watching Fight Club, Die Hard, or Heat, but liking Casino. 0:05:05 - 0:06:55: Sal's decline in watching TV/movies, watching news and old wrestling/Sopranos. 0:06:55 - 0:09:00: Jon Hamm show, Tylenol Wars documentary on Netflix. 0:09:00 - 0:11:45: Andrew from Westchester calls in, discussing the Tylenol Wars and Halloween candy incidents from their childhood. 0:11:45 - 0:15:35: Andrew criticizes Sal for not watching the NBA Finals, leading to a debate about job descriptions and watching non-New York sports. 0:15:35 - 0:19:15: Discussion continues on NBA Finals interest, small markets, and declining ratings, with Sal admitting he forgot a game was on. 0:19:15 - 0:21:45: Sal defends his opinion on TJ McConnell crying, and the conversation shifts back to movies with Mark from Huntington calling in. 0:21:45 - 0:23:45: Mark questions Sal for not seeing Gladiator, another "man card" movie. 0:23:45 - 0:25:35: Discussion about Halliburton's Achilles injury and the impact on the Pacers. 0:25:35 - 0:27:00: Dino from Bayside, Queens calls in, talking Yankees and a Cincinnati pitcher. 0:27:00 - 0:29:45: Discussion on Orel Hershiser, pitch counts, and the evolution of pitching/scouting in baseball. 0:29:45 - 0:31:45: Chris from Bayshore calls in, recommending The Clubhouse Red Sox documentary and general sports documentaries. 0:31:45 - 0:34:10: Hard Knocks discussion, its diminishing value due to increased access, and other documentaries (Full Swing, Bin Laden doc). 0:34:10 - 0:35:45: Anthony in East Brunswick calls in, criticizing Sal for not seeing Die Hard. 0:35:45 - 0:37:30: Debate over The Patriot movie and the turning of the tables on Sal regarding his movie knowledge. 0:37:30 - 0:39:15: Discussion shifts back to the Mets' struggles and the need for a big trade. 0:39:15 - 0:41:45: Rick Pitino's tweet trolling the Mets with a Grimace picture, and the absurdity of Mets gimmicks. 0:41:45 - 0:43:20: Anthony from the Bronx calls in, discussing Mets trade targets and opposition to Luis Robert and a deGrom reunion. 0:43:20 - 0:45:00: Discussion on a potential deGrom reunion, his contract, health, and attitude. 0:45:00 - 0:46:25: Caller Joe's funny story about a host not watching a game, and Uncle John's texts ripping the Mets broadcast. 0:46:25 - 0:47:35: Final thoughts on deGrom and the Mets' needs.
The Drive with Paul Swann for Friday, June 20, 2025 Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:
On this episode. 'Marketing The Magic...' author Rob Anspach joins Jen and Frank! In 'Marketing The Magic: Behind The Scenes Business Strategies from Walt Disney World', Rob takes you on an exclusive deep dive into the strategies that make Disney the most beloved brand in the world. From the psychology of anticipation to the art of upselling, from building emotional loyalty to creating an omnipresent brand, this book reveals the hidden business lessons Disney has mastered—and how you can use them to create unforgettable experiences for your customers. Get a vacation quote from Vasilia at ET Family Travel today! *** Dillo's Diz 55 Gerard St. #987. Huntington, NY 11743 Affiliate Links Music & Themes produced by Matt Harvey. Feedspot's Top 25 Siblings Podcasts You Must Follow AND Top 100 Disney Podcasts You Must Follow. ONE STOP SHOP ALL THE @DillosDiz LINKS! DIllo's Diz Resort Guests: Theme Park Rob, Jeffers, Skipper Bob, Nathaniel Hardy, Louis and Dr. Val of #FigmentsInTime, Lee Taylor, Maz, Troy with the Disney Assembled Podcast, Judy Van Cleef, Ryan Alexander, PixieDustPhD, Jason Romans, Holly Maddock, Lexi Andrea, Adam Elmers, DCLDuo, Disney Assembled Question or Comment? We LOVE interacting with listeners! FOLLOW Dillo's Diz on INSTAGRAM: https://www.instagram.com/dillosdiz/ FOLLOW Dillo's Diz on YOUTUBE: https://www.youtube.com/dillosdiz FOLLOW Dillo's Diz on TWITTER: https://twitter.com/dillosdiz
The Drive with Paul Swann for Thursday, June 19, 2025 Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
Why isn't Scotland at war with us about this show. But HEATHER loves it. And Danielle is her FRIEND. A lot of rando sexy talk. Welcome. Copilotsreadingseries.com IG: @copilots_reading_series @hrhuntington @yaydanielle Donate to The Dork Forest if you like the show. The paypal is my email jackie@jackiekashian.com and venmo is jackiekashian. Links to everything is at www.dorkforest.com or www.jackiekashian.com THERE IS NEW MERCH: BEES TSHIRT and BEANIES. I'm Made of BEES. Are you? www.JackieKashianStore.com is the direct. www.jackiekashian.com and www.dorkforest.com have so many other things. Extra TDF / standup and a storytelling album are available here: https://thedorkforest.bandcamp.com/ Lots of stuff here: https://www.youtube.com/@JackieKashianInc And it's @jackiekashian on all the social mediaz. Audio and Video by Patrick Brady Music is by Mike Ruekberg Learn more about your ad choices. Visit megaphone.fm/adchoices
The Rockies have found their bats on this road trip. Hunter Goodman has led the way and other guys in the lineup are starting to come around like Michael Toglia and Ryan McMahan. While in Atlanta, Drew had a chance to catch up with our old pal Walt Weiss who has some thoughts on the Rockies current predicament.
Today on The Drive with Paul Swann: Matt Beaven, Director of Equipment Operations for Marshall Football, joins the show. Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
Decca Aitkenhead was nine when a GP risked jail to help her mother to die. Years later she watched her best friend succumb to the slow torture of Huntington's disease, and for a few days she found herself confronting her own death. She tells Jane Mulkerrins how those experiences have shaped her views on assisted dying. This podcast was brought to you thanks to the support of readers of The Times and The Sunday Times. Subscribe today: http://thetimes.com/thestoryGuest: Decca Aitkenhead, Chief Interviewer, The Sunday Times.Host: Jane Mulkerrins.Producer: Edward Drummond.Further reading: I was 9 when a GP risked jail to help mum die. The law must changeFurther listening: The debate about death that split the countryClips: ITV/Concord Media, Parliament.Photo: Decca Aitkenhead. Get in touch: thestory@thetimes.com Hosted on Acast. See acast.com/privacy for more information.
Scott Porter (Ginny & Georgia, Friday Night Lights) joins me this week to discuss his transition from singing wide receiver to acting and how his pursuit in Hollywood allowed him to reconnect with lost family. Scott talks about the unexpected challenges and growth he's experienced on Ginny & Georgia, including the surprises of the ‘balance' show's success on Netflix. We also get into overcoming anxiety before performances, his passion for spreading awareness for Huntington's Disease, and learning the most when a situation goes wrong. Thank you to our sponsors:
Today on The Drive with Paul Swann: Marshall women's basketball coach Juli Fulks joins the show to talk about year two with the Herd — her returning core, new additions, and the next steps for the program. Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
44% of men die prematurely in Canada. Most likely higher in the US. But what about men with Huntington's Disease?
After a humiliating day teaching at the local community college in Worcester, Massachusetts, Disciple tries to focus on his writing but is pulled by his past into another conflict with his wife, Abasiama. The Huntington continues the sweeping nine-play Ufot Family Cycle and announces plans for runboyrun, the powerful drama written by Mfoniso Udofia and directed by Christopher V. Edwards. The third play in Boston's epic nine-play Ufot Family Cycle, runboyrun will be recorded and made nationally available as a podcast in partnership with the Boston Public Library, GBH, and Next Chapter Podcasts. Learn more about your ad choices. Visit podcastchoices.com/adchoices
The Drive with Paul Swann for Monday, June 16, 2025 Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
This week on Sustainability Now!, your host, Justin Mog, is delighted to get a chance to catch up with Dr. Luz Huntington-Moskos about environmental health and disaster preparedness in Kentucky. Luz was last on the program in 2021, when the Center was fairly new and today we'll get to hear how things have evolved since then. This program is a follow-up to our May 19th conversation with Luz's colleagues at CIEHS, Cat Aiton & Sarah Jump - Listen at https://soundcloud.com/wfmp-forward-radio/sustainability-now-cat-aiton-sarah-jump-uofl-center-for-integrative-environmental-health-science-5-19-25 In addition to serving on the UofL Sustainability Council, Luz is an Associate Professor of Nursing Education at the University of Louisville and Director of the Community Engagement Core at UofL's Center for Integrative Environmental Health Sciences. Learn more at https://louisville.edu/ciehs/cores/cec/cec Dr. Huntington-Moskos' research has focused on the prevention of lung cancer by addressing secondhand smoke and radon exposure in the homes of low-income families with children. Using a life course perspective, she is interested in addressing cancer prevention early in the trajectory of a child's life through the use of home testing for chronic environmental exposures. Her educational background includes a strong foundation in maternal child health and health disparities. As a recipient of two Maternal Child Health Bureau (MCHB) traineeships, she completed specialized training in child health theory, growth/development and adolescent resiliency. Her PhD dissertation examined the impact of tobacco use behaviors and secondhand smoke exposure on the cardiovascular health of rural adolescents. As a postdoctoral scholar with the Bridging Research Efforts and Advocacy Toward Healthy Environments (BREATHE) research team at the University of Kentucky, College of Nursing, she assisted in participant recruitment and expanded her knowledge of intervention research and home testing. As a co-investigator, funded by a National Institute of Environmental Health Sciences (NIEHS) diversity supplement, she examined the influence of having children in the home and the completion of home testing for radon and secondhand smoke. She has experience working with under-resourced communities during her service in the United States Peace Corps, as a registered nurse working in inner city Baltimore and on the Navajo Nation. As always, our feature is followed by your community action calendar for the week, so get your calendars out and get ready to take action for sustainability NOW! Sustainability Now! is hosted by Dr. Justin Mog and airs on Forward Radio, 106.5fm, WFMP-LP Louisville, every Monday at 6pm and repeats Tuesdays at 12am and 10am. Find us at https://forwardradio.org The music in this podcast is courtesy of the local band Appalatin and is used by permission. Explore their delightful music at https://appalatin.com
The best way to cultivate & nurture the best qualities of humanity is to first develop these qualities in ourselves. This is the mantra of my cosmic guest this week, Reverend Lynn LaBorde Eastman. When Lynn LaBorde Eastman was 11 years old, her mother gave her a copy of The Sleeping Prophet, a chronicle of the life of Edgar Cayce. Lynn's journey, from her early exposure to Edgar Cayce so many years ago through decades of spiritual growth and transcendence, has made her into the healer, teacher, and mentor that she is today. Lynn calls herself a Transformational Alchemist, helping turn people's personal darkness into light as an alchemist turns lead into gold. Lynn's greatest strength, however, is that by harnessing the spiritual and healing wisdom of the ages, she sees the clearest path to help her clients return to the healthy natural state that is the birthright of the sacred, beloved, and divine beings they truly are.On this Guest episode Lynn shares about her beautiful spiritual journey and touches on many topics including Akashic Records and knowing your soul purpose, calling in destined abundance, quantum healing stepping into the power within, healing trauma through energy work, and channeling. Lynn shares about the correlation between energy healing and trauma, how ro explore channeling abilities, and what the knowledge of the Akashic Records can teach us.Bio:Rev. Lynn Ann LaBorde is a psychic medium and the Founder of Sohmalife Sanctuary, where she serves as a Transformational Alchemist, guiding individuals to transmute personal struggles into spiritual enlightenment. With over 40 years of experience in various metaphysical practices, including advanced Pranic healing, hypnotherapy, and Reiki, Lynn has trained under renowned mentors and authored Channeling Magdalene, A Year of Love. Through her Sohmalife Sanctuary in Huntington, New York, she has hosted more than 500 events and reached an audience of over 25,000 globally, both in-person and online. Lynn's mission is to help others reconnect with their divine essence and return to their natural, healthy state as sacred beings.SOCIALS: Website: www.soulmasteryuniversity.com LinkedIn: www.linkedin.com/in/rev-lynn-laborde-eastman-684296a5/ Facebook: www.facebook.com/lynn.l.eastmanInstagram: www.instagram.com/rev_lynn_laborde/ YouTube: https://www.youtube.com/@Sohmalife
On this episode, siblings chat with siblings as Jen and Frank are joined by Rick and Bob Allen. Sons of a Disney Legend, Rick and Bob share personalanecdotes spanning their combined careers in Walt Disney Imagineering, and Operations at Disney Parks and Resorts around the world. Learn more about Rick HERE Learn more about Bob HERE Learn more about 'Of Mice and Men' HERE Get a vacation quote from Vasilia at ET Family Travel today! *** Dillo's Diz 55 Gerard St. #987. Huntington, NY 11743 Affiliate Links Music & Themes produced by Matt Harvey. Feedspot's Top 25 Siblings Podcasts You Must Follow AND Top 100 Disney Podcasts You Must Follow. ONE STOP SHOP ALL THE @DillosDiz LINKS! DIllo's Diz Resort Guests: Theme Park Rob, Jeffers, Skipper Bob, Nathaniel Hardy, Louis and Dr. Val of #FigmentsInTime, Lee Taylor, Maz, Troy with the Disney Assembled Podcast, Judy Van Cleef, Ryan Alexander, PixieDustPhD, Jason Romans, Holly Maddock, Lexi Andrea, Adam Elmers, DCLDuo, Disney Assembled Question or Comment? We LOVE interacting with listeners! FOLLOW Dillo's Diz on INSTAGRAM: https://www.instagram.com/dillosdiz/ FOLLOW Dillo's Diz on YOUTUBE: https://www.youtube.com/dillosdiz FOLLOW Dillo's Diz on TWITTER: https://twitter.com/dillosdiz
Jeff McKay, the founder and long-time proprietor of Huntington's Summit Beer Station, says he is selling the bar and readying for a major career move. Hear all about it on Episode 99 of the West Virginia Beer Roads podcast. For… Continue Reading… The post Big career move for Jeff McKay appeared first on BrilliantStream.
The Drive with Paul Swann for Thursday, June 12, 2025 Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
DJ Mo Radio - Mo Music. Mo Variety. In The Mix. - WPRK 91.5 Winter Park-Orlando, FL Fridays 5-7pm EST - Super Station 104.5 Huntington, WV - Mondays-Thursdays 9-11pm EST & Fridays 5-7pm EST - Sundays 8pm-12am EST - 93.3 Tiger FM Fort Myers, FL - Website: http://www.djmoradio.com Facebook: https://www.facebook.com/djmoradio Instagram: https://www.instagram.com/djmoradio DJ Mo Booking: 407-501-6345 Email: djmoradio@gmail.com
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Today on The Drive with Paul Swann: Marshall Assistant Volleyball Coach Maci Watrous and Tyler Kennett from HD Media join the show. Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
Daily Soap Opera Spoilers by Soap Dirt (GH, Y&R, B&B, and DOOL)
Click to Subscribe: https://bit.ly/Youtube-Subscribe-SoapDirt General Hospital fans are thrilled with the news of Kelly Thiebaud's return to on the ABC soap opera. Thiebaud, who played the character Britt Westbourne from 2012 until her demise at the hands of Heather Webber in 2023, is set to reappear on the popular soap opera. Whether she will reprise her role as Britt or be introduced as a new character is yet to be revealed. Britt Westbourne's death in the show was attributed to Huntington's disease, an incurable condition she inherited from her nefarious father, Cesar Faison (Anders Hove). General Hospital has a history of finding creative ways to resurrect characters, often utilizing the character's mother, Liesl Obrecht's (Kathleen Gati), knowledge of unconventional science and medicine. Fans are also excited at the potential of reigniting the chemistry between Britt and Jason Morgan (Steve Burton), as well as her mischievous friendship with Brad Cooper (Parry Shen). The return of Britt would also stir the pot for existing characters like Emma Drake (Braedyn Bruner) and Rocco Falconieri (Finn Frances Carr), among others. Soap Dirt is the most subscribed to Youtube soap opera channel. Visit our General Hospital section of Soap Dirt: https://soapdirt.com/category/general-hospital/ Listen to our Podcasts: https://soapdirt.podbean.com/ Check out our always up-to-date General Hospital Spoilers page at: https://soapdirt.com/general-hospital-spoilers/ Check Out our Social Media... Twitter: https://twitter.com/SoapDirtTV Facebook: https://www.facebook.com/SoapDirt Pinterest: https://www.pinterest.com/soapdirt/ TikTok: https://www.tiktok.com/@soapdirt Instagram: https://www.instagram.com/soapdirt/
We're coming to you this week from the Long Island Aquarium to celebrate their 25th Anniversary—right in front of the Shark Tank! Joining us is Bryan DeLuca, Executive Director of the aquarium and long-time friend of Discover Long Island, to talk about all the exciting happenings in honor of this milestone celebration.We're also thrilled to announce that Stacy Black, our VP of Strategy and fan-favorite from Long Island Tea, has officially been named our new full-time co-host!The ladies dive into all things Long Island life, from fun local mysteries like the Montauk Monster to our new photo contest to find the next cover of our Inspiration Guide—and so much more!#LongIslandLife From playful sea lions and majestic sharks to colorful coral reefs and hands-on touch tanks, this aquatic wonderland is a splash of fun for all ages. Whether you're watching penguins waddle or butterflies flutter in the indoor garden, every corner of the aquarium is bursting with discovery and delight. Perfect for curious kids, ocean lovers, and anyone ready to explore the magic of the deep blue sea!This summer, the Long Island Aquarium kicks off its 25th anniversary with 25 weeks of family-friendly fun, featuring special events and deep discounts. Sponsored by Bank of America and partnered with Discover Long Island, the Long Island Aquarium's 25th Anniversary is set to be an unforgettable experience.www.longislandaquarium.comCONTEST ALERT! SHOW US YOUR LONG ISLAND!Enter Our Photo Contest to Be Featured on the Cover of our Visitor Guide!We're inviting locals, visitors, and passionate photographers to share your favorite Long Island moments with us. We want to see Long Island through your lens!
The Drive with Paul Swann for Tuesday, June 10, 2025 Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
Good morning from Pharma and Biotech Daily: the podcast that gives you only what's important to hear in Pharma and Biotech world. Metsera's new long-acting amylin injection, met-233i, has shown promising weight loss results over eight months, leading to a rise in shares. Meanwhile, CDC vaccine advisors are either being pushed out or leaving their positions. Other top stories include Sirna's expansion beyond the liver, Keros returning $375 million to investors, and ACIP members receiving termination notices. In vitro cell research is focused on slowing aging and preventing age-related diseases. Updates on Merck's oral PCSK9 inhibitor, Sanofi and Regeneron's Dupixent effectiveness, and Avidity's muscular dystrophy drug are also highlighted.The expansion of RNA therapeutics is discussed, with multiple companies aiming to target small interfering RNA to various organs by 2030. Uniqure's regulatory progress in developing a gene therapy for Huntington's disease has sparked optimism, although past disappointments for patients are noted. Perspective Therapeutics presents new data on neuroendocrine tumor treatment at ASCO25. Concerns about RFK Jr.'s vaccine campaign and its potential to increase distrust in vaccines are raised in the editorial. Cancer news, cell and gene therapy updates, upcoming events, job listings, and a call for reader suggestions on coverage topics are also covered.
In this episode of Research Renaissance, host Deborah Westphal welcomes Dr. Yvette Wong, Assistant Professor of Neurology at Northwestern University and 2024 Toffler Scholar, for a deep dive into the dynamic inner world of cells—and how her lab is uncovering new clues about neurodegenerative diseases by studying the microscopic interactions between organelles.Dr. Wong discusses how organelles like mitochondria and lysosomes don't just function in isolation—they actually “talk” to each other at contact points within cells. These cellular conversations may hold the key to unlocking better understanding and treatments for conditions like ALS, Parkinson's, and Huntington's disease.Through vivid analogies (like buses exchanging cargo), Dr. Wong helps translate complex science into clear visuals, while also highlighting how advances in super-resolution live-cell microscopy and data analysis are transforming what's possible in neuroscience.
Today on The Drive with Paul Swann: Marshall Track & Field graduate Ethan Bowens, the 2025 Sun Belt Conference Overall Male Postgraduate Scholarship Award winner. Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
After getting their first sweep of the season last week, the Rockies seem to have more of a buy in around the clubhouse. Hot hitting catcher Hunter Goodman joins Drew to talk about his mindset and approach to the game this season, and who he seeks counsel with. The NBA and NHL have seen two shockiing firings this post-season.
The Drive with Paul Swann for Friday, June 6, 2025. Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma e Biotech world. Fired employees from the Department of Health and Human Services are suing Robert F. Kennedy Jr. and Elon Musk, claiming their terminations were based on inaccurate and error-ridden information. The lawsuit alleges that HHS leadership knew the records used to guide layoff decisions were flawed. UniQure's regulatory progress has sparked optimism for Huntington's disease patients, with analysts reacting positively to the company's accelerated approval pathway for a gene therapy submission in 2026. Cullinan has made a back-heavy deal in China worth over $700 million for autoimmune T cell engager technology, while Sarepta has won FDA's platform technology designation for gene therapy development. Rapt is shrinking after discontinuing a drug, agileAD is gearing up to challenge J&J in the multiple myeloma Car-T market, and Lilly has signed a deal for long-acting obesity drugs.
On this episode, Jen and Frank salute one attraction, MuppetVision 3D, from their first visit three months after its 1991 opening to this week's closure. Get a vacation quote from Vasilia at ET Family Travel today! *** Dillo's Diz 55 Gerard St. #987. Huntington, NY 11743 Affiliate Links Music & Themes produced by Matt Harvey. Feedspot's Top 25 Siblings Podcasts You Must Follow AND Top 100 Disney Podcasts You Must Follow. ONE STOP SHOP ALL THE @DillosDiz LINKS! DIllo's Diz Resort Guests: Theme Park Rob, Jeffers, Skipper Bob, Nathaniel Hardy, Louis and Dr. Val of #FigmentsInTime, Lee Taylor, Maz, Troy with the Disney Assembled Podcast, Judy Van Cleef, Ryan Alexander, PixieDustPhD, Tony Orgelfinger, Holly Maddock, Lexi Andrea, Adam Elmers, DCLDuo, Disney Assembled Question or Comment? We LOVE interacting with listeners! FOLLOW Dillo's Diz on INSTAGRAM: https://www.instagram.com/dillosdiz/ FOLLOW Dillo's Diz on YOUTUBE: https://www.youtube.com/dillosdiz FOLLOW Dillo's Diz on TWITTER: https://twitter.com/dillosdiz
The Drive with Paul Swann for Thursday, June 5, 2025. Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
DJ Mo Radio - Mo Music. Mo Variety. In The Mix. - WPRK 91.5 Winter Park-Orlando, FL Fridays 5-7pm EST - Super Station 104.5 Huntington, WV - Mondays-Thursdays 9-11pm EST & Fridays 5-7pm EST - Sundays 8pm-12am EST - 93.3 Tiger FM Fort Myers, FL - Website: http://www.djmoradio.com Facebook: https://www.facebook.com/djmoradio Twitter: https://www.twitter.com/djmoradio Instagram: https://www.instagram.com/djmoradio DJ Mo Booking: 407-501-6345 Email: djmoradio@gmail.com
Today on The Drive with Paul Swann: Bri Ellis, Assistant Director of Women's Basketball Operations at Marshall University. Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
This week we talk about gene-editing, CRISPR/Cas9, and ammonia.We also discuss the germ line, mad scientists, and science research funding.Recommended Book: The Siren's Call by Chris HayesTranscriptBack in November of 2018, a Chinese scientist named He Jiankui achieved global notoriety by announcing that he had used a relatively new gene-editing technique on human embryos, which led to the birth of the world's first gene-edited babies.His ambition was to help people with HIV-related fertility problems, one of which is that if a parent is HIV positive, there's a chance they could transmit HIV to their child.This genetic modification was meant to confer immunity to HIV to the children so that wouldn't be an issue. And in order to accomplish that immunity, He used a technology called CRISPR/Cas9 to modify the embryos' DNA to remove their CCR5 gene, which is related to immune system function, but relevant to this undertaking, also serves as a common pathway for the HIV-1 virus, allowing it to infect a new host.CRISPR is an acronym that stands for clustered regularly interspaced short palindromic repeats, and that refers to a type of DNA sequence found in all sorts of genomes, including about half of all sequenced bacterial genomes and just shy of 90% of all sequenced archaea genomes.Cas9 stands for CRISPR-associated protein 9, which is an enzyme that uses CRISPR sequences, those repeating, common sequences in DNA strands, to open up targeted DNA strands—and when paired with specific CRISPR sequences, this duo can search for selected patterns in DNA and then edit those patterns.This tool, then, allows researchers who know the DNA pattern representing a particular genetic trait—a trait that moderates an immune system protein that also happens to serve as a convenient pathway for HIV, for instance—to alter or eliminate that trait. A shorthand and incomplete way of thinking about this tool is as a sort of find and replace tool like you have in a text document on your computer, and in this instance, the gene sequence being replaced is a DNA strand that causes a trait that in turn leads to HIV susceptibility.So that's what He targeted in those embryos, and the children those embryos eventually became, who are usually referred to as Lulu and Nana, which are pseudonyms, for their privacy, they were the first gene-edited babies; though because of the gene-editing state of the art at the time, while He intended to render these babies' CCR5 gene entirely nonfunctional, which would replicate a natural mutation that's been noted in some non-gene-edited people, including the so-called Berlin Patient, who was a patient in Germany in the late-90s who was functionally cured of HIV—the first known person to be thus cured—while that's what He intended to do, instead these two babies actually carry both a functional and a mutant copy of CCR5, not just the mutant one, which in theory means they're not immune to HIV, as intended.Regardless of that outcome, which may be less impactful than He and other proponents of this technology may have hoped, He achieved superstardom, briefly, even being named one of the most influential people in the world by Time magazine in 2019. But he was also crushed by controversy, stripped of his license to conduct medical research by the Chinese government, sent to prison for three years and fined 3 million yuan, which is more than $400,000, and generally outcast from the global scientific community for ethical violations, mostly because the type of gene-editing he did wasn't a one-off sort of thing, it was what's called germ-line editing, which means those changes won't just impact Lulu and Nana, they'll be passed on to their children, as well, and their children's children, and so on.And the ethical implications of germ-line editing are so much more substantial because while a one-off error would be devastating to the person who suffers it, such an error that is passed on to potentially endless future generations could, conceivably, end humanity.The error doesn't even have to be a botched job, it could be an edit that makes the edited child taller or more intelligent by some measure, or more resistant to a disease, like HIV—but because this is fringy science and we don't fully understand how changing one thing might change other things, the implications for such edits are massive.Giving someone an immunity to HIV would theoretically be a good thing, then, but if that edit then went on the market and became common, we might see a generation of humans that are immune to HIV, but potentially more susceptible to something else, or maybe who live shorter lives, or maybe who create a subsequent generation who themselves are prone to all sorts of issues we couldn't possibly have foreseen, because we made these edits without first mapping all possible implications of making that genetic tweak, and we did so in such a way that those edits would persist throughout the generations.What I'd like to talk about today is another example of a similar technology, but one that's distinct enough, and which carries substantially less long-term risk, that it's being greeted primarily with celebration rather than concern.—In early August of 2024, a gene-editing researcher at the University of Pennsylvania, Dr. Kiran Musunuru, was asked if there was anything he could do to help a baby that was being treated at the Children's Hospital of Philadelphia for CPS1 deficiency, which manifests as an inability to get rid of the ammonia that builds up in one's body as a byproduct of protein metabolism.We all generate a small amount of ammonia just as a function of living, and this deficiency kept the baby from processing and discarding that ammonia in the usual fashion. As a result, ammonia was building up in its blood and crossing into its brain.The usual method of dealing with this deficiency is severely restricting the suffer's protein intake so that less ammonia is generated, but being a baby, that meant it wasn't able to grow; he was getting just enough protein to survive and was in the 7th percentile for body weight.So a doctor at the Children's Hospital wanted to see if there was anything this gene-editing researcher could do to help this baby, who was at risk of severe brain damage or death because of this condition he was born with.Gene-editing is still a very new technology, and CRISPR and associated technologies are even newer, still often resulting in inaccurate edits, many of which eventually go away, but that also means the intended edit sometimes goes away over time, too—the body's processes eventually replacing the edited code with the original.That said, these researchers, working with other researchers at institutions around the world, though mostly in the US, were able to rush a usually very cumbersome and time-consuming process that would typically take nearly a decade, and came up with and tested a gene-editing approach to target the specific mutation that was causing this baby's problems, and they did it in record time: the original email asking if Dr Musunuru might be able to help arrived in August of 2024, and in late-February of 2025, the baby received his first infusion of the substance that would make the proper edits to his genes; they divided the full, intended treatment into three doses, the first being very small, because they didn't know how the baby would respond to it, and they wanted to be very, very cautious.There were positive signs within the first few weeks, so 22 days later, they administered the second dose, and the third followed after that.Now the research and medical worlds are waiting to see if the treatment sticks; the baby is already up to the 40th percentile in terms of weight for his age, is able to eat a lot more protein and is taking far less medication to help him deal with ammonia buildup, but there's a chance that he may still need a liver transplant, that there might be unforeseen consequences due to that intended edit, or other, accidental edits made by the treatment, or, again, that the edits won't stick, as has been the case in some previous trials.Already this is being heralded as a big success, though, as the treatment seems to be at least partially successful, hasn't triggered any serious, negative consequences, and has stuck around for a while—so even if further treatments are needed to keep the gene edited, there's a chance this could lead to better and better gene-editing treatments in the future, or that such treatments could replace some medications, or be used for conditions that don't have reliable medications in the first place.This is also the first known case of a human of any age being given a custom gene-editing treatment (made especially for them, rather than being made to broadly serve any patient with a given ailment or condition), and in some circles that's considered to be the future of this field, as individually tailored gene-treatments could help folks deal with chronic illnesses and genetic conditions (like cystic fibrosis, Huntington's disease, muscular dystrophy, and sickle cell), but also possibly help fight cancers and similar issues.More immediately, if this treatment is shown to be long-term efficacious for this first, baby patient, it could be applied to other patients who suffer the same deficiency, which afflicts an estimated 1 in 1.3 million people, globally. It's not common then—both parents have to have a mutant copy of a specific gene for their child to have this condition—but that's another reason this type of treatment is considered to be promising: many conditions aren't widespread enough to justify investment in pharmaceuticals or other medical interventions that would help them, so custom-tailored gene-editing could be used, instead, on a case-by-case basis.This is especially true if the speed at which a customized treatment can be developed is sped-up even further, though there are concerns about the future of this field and researchers' ability to up its efficiency as, at least in the US, the current administration's gutting of federal research bodies and funding looks likely to hit this space hard, and previous, similar victories that involved dramatically truncating otherwise ponderous developmental processes—like the historically rapid development of early COVID-19 vaccines—are not looked at favorably by a larger portion of the US electorate, which could mean those in charge of allocating resources and clearing the way for such research might instead pull even more funding and put more roadblocks in place, hobbling those future efforts, rather than the opposite.There are plenty of other researchers and institutions working on similar things around the world, of course, but this particular wing of that larger field may have higher hurdles to leap to get anything done in the coming years, if current trends continue.Again, though, however that larger context evolves, we're still in the early days of this, and there's a chance that this approach will turn out to be non-ideal for all sorts of reasons.The concept of tailored gene-editing therapies is an appealing one, though, as it could replace many existing pharmaceutical, surgical, and similar approaches to dealing with chronic, inherited conditions in particular, and because it could in theory at least allow us to address such issues rapidly, and without needing to mess around with the germ-line, because mutations could be assessed and addressed on a person-by-person basis, those edits staying within their bodies and not being passed on to their offspring, rather than attempting to make genetic customizations for future generations based on the imperfect knowledge and know-how of today's science, and the biased standards and priorities of today's cultural context.Show Noteshttps://www.nejm.org/doi/full/10.1056/NEJMoa2504747https://www.nih.gov/news-events/news-releases/infant-rare-incurable-disease-first-successfully-receive-personalized-gene-therapy-treatmenthttps://www.wired.com/story/a-baby-received-a-custom-crispr-treatment-in-record-time/https://www.wsj.com/tech/biotech/crispr-gene-editing-therapy-philadelphia-infant-8fc3a2c5https://www.washingtonpost.com/science/2025/05/15/crispr-gene-editing-breakthrough/https://www.npr.org/sections/shots-health-news/2025/05/15/nx-s1-5389620/gene-editing-treatment-crispr-inheritedhttps://interestingengineering.com/health/first-personalized-crispr-gene-therapyhttps://www.nature.com/articles/d41586-025-01496-zhttps://www.nytimes.com/2025/05/15/health/gene-editing-personalized-rare-disorders.htmlhttps://www.nytimes.com/2025/05/31/world/asia/us-science-cuts.htmlhttps://www.livescience.com/health/genetics/us-baby-receives-first-ever-customized-crispr-treatment-for-genetic-diseasehttps://en.wikipedia.org/wiki/He_Jiankui_affairhttps://en.wikipedia.org/wiki/CCR5https://en.wikipedia.org/wiki/Berlin_Patienthttps://en.wikipedia.org/wiki/CRISPR_gene_editinghttps://en.wikipedia.org/wiki/CRISPRhttps://pmc.ncbi.nlm.nih.gov/articles/PMC6813942/ This is a public episode. 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The Drive with Paul Swann for Tuesday, June 3, 2025. Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
This Day in Legal History: National Defense ActOn June 3, 1916, President Woodrow Wilson signed the National Defense Act into law, marking a major shift in American military and legal policy. Passed amid growing tensions related to World War I, the Act dramatically expanded the U.S. Army and strengthened the National Guard, officially integrating it as the Army's primary reserve force. It increased the size of the Regular Army to over 175,000 soldiers and provided for a National Guard force of over 400,000 when fully mobilized. The law also created the Reserve Officers' Training Corps (ROTC), formalizing military education at civilian colleges and universities across the country.Crucially, the Act clarified federal authority over the National Guard, requiring units to conform to federal training standards and granting the president the power to mobilize them for national emergencies. This federalization of a traditionally state-controlled force marked a significant legal development in the balance between state and federal military power. It addressed long-standing constitutional ambiguities surrounding the militia clauses and reflected evolving views of national defense in a modern industrial society.The Act emerged from broader preparedness debates within the U.S. political and legal spheres, balancing isolationist tendencies with the perceived need for greater military readiness. Though the U.S. would not enter World War I until 1917, the National Defense Act of 1916 laid essential legal groundwork for rapid mobilization. It remains a foundational statute for the structure of the modern U.S. military.The U.S. Supreme Court declined to hear two significant Second Amendment challenges involving bans on assault-style rifles and high-capacity magazines in Maryland and Rhode Island. By refusing the appeals, the Court left in place lower court rulings upholding the restrictions. Maryland's law, enacted after the 2012 Sandy Hook shooting, bans certain semi-automatic rifles like the AR-15, while Rhode Island's 2022 law prohibits magazines holding more than 10 rounds. Plaintiffs in both cases argued that these weapons and accessories are commonly owned by law-abiding citizens and thus protected by the Constitution.The Court's conservative bloc showed signs of division. Justices Thomas, Alito, and Gorsuch dissented, indicating they would have reviewed the bans. Justice Kavanaugh did not dissent but issued a statement expressing openness to hearing similar cases in the future, suggesting that the Court would eventually need to rule on whether AR-15s are constitutionally protected.Lower courts rejected the challenges based on the weapons' military-style design and their use in mass killings, reasoning that they are not suitable for self-defense and thus fall outside Second Amendment protection. The challengers contended that these laws ignore the Court's prior rulings on weapons in “common use.” Despite recent decisions expanding gun rights, the justices allowed these bans to stand for now.US Supreme Court won't review assault weapon, high-capacity magazine bans | ReutersThree federal lawsuits filed on June 2, 2025, allege that major class action settlement administrators and two banks engaged in a kickback scheme that siphoned funds away from class members. The suits, brought in New York, Florida, and California, accuse Epiq Solutions, Angeion Group, and JND Legal Administration of securing illicit payments from Huntington National Bank and Western Alliance Bank in exchange for directing large volumes of settlement deposits to them. In return, the administrators allegedly received a share of the banks' profits.Plaintiffs claim the scheme dates back years and coincided with rising interest rates in 2021, which increased the potential value of settlement fund deposits. According to the lawsuits, administrators threatened to stop using the banks unless they shared profits. As a result, class members allegedly received lower payouts due to below-market interest rates on their settlement funds.Together, the defendant banks are said to control over 80% of the U.S. settlement fund market, while the administrators manage over 65% of class action services. The plaintiffs argue this arrangement violated U.S. antitrust law by reducing competition and fixing prices. JND and Western Alliance have denied wrongdoing, calling the claims baseless or inaccurate. Huntington declined to comment, and other parties have yet to respond.Class action administrators, banks accused of kickback scheme in new lawsuits | ReutersMy column for Bloomberg this week looks at Spain's proposed 100% tax on non-EU homebuyers, introduced as a bold fix for the country's deepening housing crisis. The government is responding to surging public frustration over exploding rents—up more than 60% in Barcelona in five years—and the sense that local housing is being turned into an asset class for absentee owners. But while the policy grabs attention, I argue it misses the real target. The problem isn't who owns the homes—it's how those homes are being used. A blanket nationality-based tax is a blunt instrument that's economically ineffective, legally risky under EU and international law, and symbolically inflammatory.Instead, I suggest a more focused approach: taxing speculative flipping and underutilization directly. A resale tax on homes sold within a short holding period, calibrated by how quickly they're flipped, would discourage fast-moving speculation without penalizing genuine residents or workers. Similarly, a progressive vacancy tax—getting steeper the longer a property remains empty—would address the roughly four million vacant or underused homes across Spain. These tools would pressure banks and investors to put housing back into circulation while raising revenue for public housing initiatives.Critically, these proposals are neutral as to the owner's nationality. Whether a home is owned by a Spanish bank, a Canadian retiree, or a U.S. fund manager, what matters is whether it's being used as shelter or as a sidelined asset. The column makes the case that Spain's housing crisis won't be solved by turning foreign investors into political scapegoats, but by confronting speculative behaviors that choke supply and inflate prices—regardless of the flag the buyer flies. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.minimumcomp.com/subscribe
The Drive with Paul Swann for Monday, June 2, 2025. Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
The Drive with Paul Swann for Friday, May 30, 2025 Thanks for listening to The Drive with Paul Swann!Love the show? Help keep it going and growing:☕️ Buy Paul a coffee – support the show directly: buymeacoffee.com/paulswannYour support helps bring you more in-depth coverage of Marshall Athletics, exclusive interviews, and the content you care about. Every contribution makes a difference.
The Rockies historic struggles are continuing and Drew is answering the question, how did this happen? One of a few bright spots for the Rockies is left fielder Jordon Beck. He talks about Drew about his better play and how he copes with the team's struggles.
Jen and Frank chat with Natalie and Hannah, aka The Stride Sisters, about their podcast, RUNDisney, and maybe meeting up this Fall! Get a vacation quote from Vasilia at ET Family Travel today! *** Dillo's Diz 55 Gerard St. #987. Huntington, NY 11743 Affiliate Links Music & Themes produced by Matt Harvey. Feedspot's Top 25 Siblings Podcasts You Must Follow AND Top 100 Disney Podcasts You Must Follow. ONE STOP SHOP ALL THE @DillosDiz LINKS! DIllo's Diz Resort Guests: Theme Park Rob, Jeffers, Skipper Bob, Nathaniel Hardy, Louis and Dr. Val of #FigmentsInTime, Lee Taylor, Maz, Troy with the Disney Assembled Podcast, Judy Van Cleef, Ryan Alexander, PixieDustPhD, Tony Orgelfinger, Holly Maddock, Lexi Andrea, Adam Elmers, DCLDuo, Disney Assembled Question or Comment? We LOVE interacting with listeners! FOLLOW Dillo's Diz on INSTAGRAM: https://www.instagram.com/dillosdiz/ FOLLOW Dillo's Diz on YOUTUBE: https://www.youtube.com/dillosdiz FOLLOW Dillo's Diz on TWITTER: https://twitter.com/dillosdiz
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