Podcasts about Huntington

Dennis in Huntington, NY, called Mark to ask him about where the healthcare subsidies may be headed. Vito in Staten Island, NY, wants to tell Mark that Andrew Cuomo keeps all his campaign money, whether he wins or loses the mayoral race in New York City. See omnystudio.com/listener for privacy information.

Dennis in Huntington, NY, called Mark to ask him about where the healthcare subsidies may be headed. Vito in Staten Island, NY, wants to tell Mark that Andrew Cuomo keeps all his campaign money, whether he wins or loses the mayoral race in New York City.

Jen and Frank chat the Walt Disney World and Disneyland ticket price increases. On this episode…

Griffin's favorite game that requires no arena or balls! Rachel's favorite squished-together treat!Music: “Money Won't Pay” by bo en and Augustus – https://open.spotify.com/album/7n6zRzTrGPIHt0kRvmWoyaBorder Angels: https://www.borderangels.org/

The Culture Show's Jared Bowen on Bob Ross' paintings on the auction block to support public media, "Sardines" at the Huntington,  Taylor Swift's record-breaking record sales, and other arts and culture news. Harvard national security expert Juliette Kayyem on President Trump's troop orders to Portland and Chicago, the air traffic controller debacle nationwide, and more. Political philosopher Michael Sandel (author of the celebrated 1996 book "Democracy's Discontent") joins us ahead of his GBH Ralph Lowell Annual Lecture Thursday night.Tufts food policy analyst Corby Kummer is joined by retiring Washington Post food critic Tom Sietsema, who exposes his face to us for the first time.

Ladies, it's Breast Cancer Awareness Month, so go get your boobies checked! We're also talking family lineage, growing up on a farm, and the groundbreaking treatment for Huntington's disease.00:00:00 - Introduction & Getting Started 00:02:04 - Fall Season & Halloween Decorations Debate 00:05:27 - Big Tea & Do Dog (Parent Nicknames) 00:15:27 - Big Family Reflections 00:20:08 - Family Genealogy & Lineage00:24:11 - Pop Culture & Science Discussion00:30:16 - Gene Therapy & Medical Research 00:33:07 - Eric Dane & ALS Awareness 00:37:11 - mRNA Vaccine Technology 00:38:36 - Wrapping Up & Superpower TalkMORE PODCAST EPISODES: https://youtube.com/playlist?list=PLTGuNbPgq2EartAwwgs_H-LVho3FvWnXpJUST LISTEN TO THE PODCAST: https://link.chtbl.com/imomsohardSEE US ON TOUR: (FALL DATES COMING SOON)https://www.imomsohard.com/WATCH OUR AMAZON PRIME SPECIAL: https://www.amazon.com/IMomSoHard-Live/dp/B07VBJ34DTIf you are interested in advertising on this podcast email ussales@acast.comTo request #IMOMSOHARD to be on your Podcast, Radio Show, or TV Show, reach out to talent@pionairepodcasting.comFOLLOW US: Facebook: https://www.facebook.com/imomsohardInstagram: https://www.instagram.com/imomsohard/Twitter: https://twitter.com/imomsohardGet our sponsor DISCOUNT CODES here!https://linktr.ee/imshpodcastABOUT US Female comedy duo Kristin Hensley and Jen Smedley have been performing, teaching, and writing comedy internationally for a combined 40+ years. They have been moms for one quarter of that time and it shows. How do they cope? They laugh about all of the craziness that comes with being a mom and they want you to laugh about it too! From snot to stretchmarks to sleepless nights, Kristin and Jen know firsthand that parenting is a hard job and they invite you to join them in taking it all a little less seriously (even if for a few short minutes a day). After all, Jen currently has four days of dry shampoo in her hair and Kristin's keys are still in her front door. They try, they fail, they support each other, and they mom as hard as they can.Disclaimer: This podcast is for entertainment purposes only. Views expressed on this podcast solely reflect those of the host and do not reflect the views of Pionaire. Hosted on Acast. See acast.com/privacy for more information.

Surf beef, soft-tops, and the hottest gossip in surfing! all in one episode. Sterling Spencer and Cousin Ryan break down a spicy Huntington vs North Shore incident, Lower Trestles madness, Gerry Lopez still styling at 75, finger-flip airs (skate tricks in the water!), and the true origin story of the thruster (Simon Anderson, we salute you). We tour Billabong House lore, Andy's board stash, groms in stand-up pits, and why lineup etiquette still matters. Plus: quads vs thrusters, boogie-board respect, hurricane missions on Tom Curren's Black Beauty, and whether the “right board” gets too much credit.If you love surfing, skate culture, and comedy podcasts (with a side of chaos), you're home. Smash LIKE, drop a COMMENT (team twin, thruster, or quad?), and SUBSCRIBE for weekly surf-comedy deep dives, Core Lord vs Soft-Top debates, and clips from around the world.#surf #surfpodcast #surfculture #surfingcomedy #skateboarding #skateculture #longboarding #shortboard #softtop #corelord #lowerstrestles #northshore #huntingtonbeach #gerrylopez #thruster #simonanderson #andyirons #groms #kellyslater #boogieboardFuel of the pod: West Peak. Get 20% off at drinkwestpeak.com with code PINCHMYSALT — delivered to your door.

The Guardian journalist Josh Halliday talks about Huntington's disease, the impact the rare inherited condition has had on his family and the hope there may now be a treatment. Help support our independent journalism at theguardian.com/infocus

The Broncos checked a lot of boxes in their huge road win at Philadepha.  Among them, Bo Nix showing he can lead his team from behind in a big moment.  There was another instance of a player dropping the football before entering the endzone.  The CU Buffs are struggling and the CSU Rams are sinking like a rock. Ryan Spilborgs joins Drew to discuss the departure of Bill Schmidt and what lies ahead for the Rockies 

Michael Clary grew up in Huntington, West Virginia, in the shadow of the Marshall University plane crash that marked his hometown. Ministry ran deep in his family line—his great-grandfather and grandfather were both Baptist preachers—but his own childhood was shaken when his parents divorced at age seven. Shuttling between households, Michael experienced both the steady example of his Christian father and the destructive influence of a tyrannical stepfather. Those early wounds left him with a deep burden for healthy, Christ-centered homes.Though he professed faith from a young age, Michael's spiritual growth accelerated through Campus Crusade for Christ at Marshall University. Immersed in Bible study, evangelism, and worship leadership, his heart for ministry took root. It was during a summer project with Crusade that he met Laura, the shy young woman who would later become his wife. Married in 1999, Michael and Laura went on staff with Crusade before sensing God's call to local church ministry.In 2010, with nothing but faith and a handful of families meeting in his basement, Michael planted Christ the King Church in Cincinnati. Over 15 years, the church has grown, planted daughter churches, and recently moved to a new facility in Fort Thomas, Kentucky. Along the way, Michael's convictions deepened around biblical manhood, womanhood, and family life—shaped by both his wounds and God's grace. Today, he continues to serve as lead pastor, husband to Laura, and father to four children, proclaiming God's good design for households and the church

Who knew that learning how to buddy tape fingers would lead to a decades long career in Athletic Training? That is exactly where Jeff Carrico started in grade school thanks to his coach Pat Lewis. Jeff started to find his athletic training groove at LaSalle HS, (Cincinnati, OH) as their student athletic trainer and then on to Eastern Kentucky University to learn from NATA HOF athletic trainer, Dr. Bobby Barton. Work ethic and previous AT experience allow for Jeff to right to work at EKU. Working various sports but spending most of his time with Dr. Barton and Football. After getting his undergraduate degree he landed a GA position at Northern Illinois University in 1994. Carrico ended up getting hired as an assistant athletic trainer at NIU and staying until 1997. Jeff then headed to Huntington, WV to become the assistant athletic trainer at Marshall University and in 1999 he became the Head Athletic Trainer. 2007 Jeff had the opportunity to come home and become the assistant athletic director for sports medicine at the University of Cincinnati working with men's and women's basketball. Carrico then moved on to DePaul University in 2012 working with men's basketball. A 2 year stint at Central Michigan University as an associate athletic trainer with men's basketball and then finally back to EKU as the Assistant Athletic Director for Sports Medicine until 2023.Currently Jeff is an outreach athletic trainer with UK Health Care in Lexington, KY. He recently received the Award of Merit from the Kentucky Athletic Trainers' Society and was inducted into the Marshall University Sports Medicine Hall of Fame in 2010.He resides in Richmond, KY.

Abdul and Katelyn discuss the latest news in public health, which includes: Trump's $100,000 H1-B visa fee, which is could significantly hurt staffing in rural hospitals A new 100% tariff on certain imported brand-name drugs RFK Jr's announcement that the FDA is re-evaluating the abortion medication mifepristone A new scientific breakthrough that's giving hope to people with Huntington's Disease Then Abdul sits down with Dr. Aziz Rahman, an American physician who recently completed a medical mission in Gaza. Dr. Rahman offers a gripping account of the devastation in Gaza, and the heroic efforts of doctors serving there. Check out our shop at store.americadissected.com for our new America Dissected merch – including logo shirts, hoodies and mugs. And don't miss our “Vaccines Work. Science Matters.” t-shirts! This show would not be possible without the generous support of our sponsors. America Dissected invites you to check them out. This episode was brought to you by: Boll & Branch: For a limited time get 20% off your first set of sheets plus free shipping at BollAndBranch.com/AD. Quince: Go to Quince.com/AD for free shipping on your order and 365-day returns. APHA: Listeners of this podcast get a 10% discount for the 2025 Annual Meeting and Expo using code: Dissected25.

Bill Schmidt stepped aside today two days after the Rockies concluded their worst season in franchise history.  Drew has details on possible candidates for the GM job and a what the steps need to be to turn things around.  Also Drew has a post-mortum on the Rockies season and how it got as bad as it did.  

Jen and Frank chat about the nostalgia behind Mickey's Not-So-Scary Halloween Party. On this episode…

00:50 How ancient viruses drive modern human developmentResearch suggests that ancient viral-DNA embedded in the human genome is playing a key role in early embryo development. Around 8% of our genome consists of endogenous retrovirus DNA — the remnants of ancient infections, but knowledge of their activity is limited. Now, a team show that these sequences are required for the correct development of lab-derived embryo analogues, and for the switching on of human-specific genes.Research Article: Fueyo et al.News and Views: Ancient viral DNA in the human genome shapes early development10:39 Research HighlightsLonger whale mothers are more likely to give birth to daughters — plus, how the stink of the corpse flower waxes and wanes to attract pollinators.Research Highlight: Big mother whales have more daughters than sonsResearch Highlight: Corpse flowers waft out stinky compounds as fast as landfills do13:05 How heat can fuel DNA computersResearchers have developed a way to use heat to recharge DNA-based computer circuits, which could help overcome one of the stumbling blocks preventing this technology from being scaled up. Although DNA strands have been used to perform computational tasks for some time, current methods can run out of energy or build up waste products, preventing their continued use. Now, using just heat a team have demonstrated a reuseable neural network based on DNA. They hope that ultimately this could be a step in the development of bigger and more powerful DNA computers that could be used to power targeted clinical therapies.Research Article: Song & Qian22:20 Briefing ChatA one-time gene therapy for Huntington's disease show promise at slowing the brain disorder's progression — plus, how mitochondria throw out ‘tainted' DNA.Nature: Huntington's disease treated for first time using gene therapyNature: Mitochondria expel tainted DNA — spurring age-related inflammationSubscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday. Hosted on Acast. See acast.com/privacy for more information.

A major medical breakthrough is offering some hope for families battling Huntington's disease.

New hope for sufferers of Huntington's disease after the discovery of a treatment which could radically slow the disease. Writer: James TapperProducer: Poppy BullardHost: Ada BarumeEpisode photography: Sophia FentonExecutive Producer: Jasper Corbett Hosted on Acast. See acast.com/privacy for more information.

Genmab closed out a busy third quarter for M&A in biopharma, picking up cancer biotech Merus for $8 billion. This deal—the year's fifth largest—came just a week after Pfizer acquired rising obesity star Metsera for $4.9 billion. Just seven days later, Metsera made the New York–based pharma look like a genius with mid-stage data for one of the deal's centerpiece therapies, MET-097i, showing 14% placebo-adjusted weight loss over 28 weeks.After months of tarrying and threats, President Donald Trump announced last week that 100% tariffs would take effect Oct. 1—with broad exceptions for companies that have taken steps to build out their domestic manufacturing footprints. One company that has answered that call—as well as a letter sent by the president to 17 of the largest pharma companies requesting action on his most-favored-nation drug pricing policy—is Pfizer. In a joint oval office announcement with Pfizer CEO Albert Bourla and HHS officials, Trump said Pfizer would offer all new medicines at MFN prices.Meanwhile, over at the FDA, CDER Director George Tidmarsh, who has flown relatively under the radar since taking the post in July, took to LinkedIn to address the subject of relying on surrogate endpoints in drug approvals. In a since deleted post, Tidmarsh called out Aurinia Pharmaceuticals' lupus drug as an “egregious” example of this phenomenon. CDER's sister agency, CBER, also made a splash last week, publishing three draft recommendations intended to accelerate the development of cell and gene therapies.Speaking of CGT, maybe the biggest clinical development news of the year emerged from this space last week when uniQure announced that its gene therapy for Huntington's disease, AMT-130, slowed disease progression by 75% after three years. With these data in hand, uniQure plans to file for FDA approval of the treatment in the first quarter of 2026. If successful, AMT-130 would be the first genetic therapy for the intractable neurodegenerative disease.Finally, biopharma's glass ceiling just got a little more tightly sealed. Emma Walmsley, the industry's first female CEO, is stepping down after nine years at GSK, handing the reins to current chief commercial officer, Luke Miels. When Walmsley officially departs on Dec. 31, she will leave Vertex CEO Reshma Kewalramani and incoming Takeda CEO Julie Kim to represent the sisterhood at the highest ranks of the biopharma industry.

Queridos Curiosinautas, llega un nuevo episodio

Audio roundup of selected biopharma industry content from Scrip over the business week ended September 26, 2025. In this episode: Pfizer jumps back into obesity with Metsera bid; Roche maps out its obesity ambitions; UniQure's encouraging gene therapy results for Huntington's; BMS plans US pricing for Cobenfy in the UK; and vaccine skepticism affects vaccine commercial prospects. https://insights.citeline.com/scrip/podcasts/scrips-five-must-know-things/quick-listen-scrips-five-must-know-things-HCVAK32IGREDHMH5D4I3RFY6AA/ This episode was produced with the help of AI text-to-voice and voice emulation tools. Playlist: soundcloud.com/citelinesounds/sets/scrips-five-must-know-things

Good morning from Pharma and Biotech Daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.Genmab has acquired Merus, a rising star in the field of oncology, for $8 billion. The acquisition includes Merus' bispecific antibody, petosemtamab, which targets EGFR and LGR5 and has shown potential for head-and-neck cancer. In other news, GSK CEO Emma Walmsley is stepping down after nine years, with Chief Commercial Officer Luke Miels set to replace her next year. The FDA's decision to disclose complete response letters in real-time has raised questions about transparency and the agency's role. Additionally, Biogen has shuffled staff after ending work on AAV, while Heidelberg has cut 75% of its staff after missed royalty payments.The FDA's real-time disclosure of complete response letters benefits investors by providing greater visibility into regulatory decisions. In September, the FDA's actions included boosting Keytruda while rejecting two spinal muscular atrophy therapies due to manufacturing issues. A judge's ruling on the FDA's authority over laboratory-developed tests reflects the impact of a recent Supreme Court decision. Six FDA decisions to watch for in Q4 could have significant implications for the biopharma industry and patients. Recent developments include positive results for an immuneering asset in pancreatic cancer, FDA approval for Lilly's oral SERD for breast cancer, and positive outcomes for uniQure's Huntington's therapy. Additionally, the FDA is streamlining development of cell, gene, and regenerative therapies. Other news includes the revival of a dormant drug as a potential autism treatment, setbacks in obesity studies, and unexpected rejections for certain therapies. Upcoming webinars and job opportunities are also highlighted.Listeners are encouraged to provide feedback on topics they would like to see covered in future episodes.

Welcome to RIMScast. Your host is Justin Smulison, Business Content Manager at RIMS, the Risk and Insurance Management Society.   In this episode, Justin interviews James Swanke, Lecturer in Risk and Insurance at the University of Wisconsin-Madison's Wisconsin School of Business. He currently serves as Director of the Risk Management and Insurance MBA program. Justin and Jim talk about his 42 years of experience in Risk Consulting with Willis Towers Watson, and his specialties there, particularly with captives. They discuss the University of Wisconsin-Madison Risk Management and Insurance MBA program, what the students learn, and the competitions they have won in the last year, and they look forward to winning this year. Also, Jim tells of disc jockeying in college, from Classic Rock to Polka.   Listen to learn about captive design, how to prepare for emerging trends, and who wrote the best music of the '70s.   Key Takeaways: [:01] About RIMS and RIMScast. [:17] About this episode of RIMScast. This is our special International Podcast Day episode because it's released on September 30th. We will be joined by Jim Swanke. He's a lecturer in the Risk Management Program of the University of Wisconsin. [:46] Jim started his career in broadcasting, and he still has the voice. We've got a lot to talk about today! [:54] RIMS-CRMP Prep Workshops! The next RIMS CRMP Prep Workshops will be held on October 29th and 30th and led by John Button. [1:06] The next RIMS-CRMP-FED Virtual Workshop will be held on November 11th and 12th and led by Joseph Mayo. Links to these courses can be found through the Certifications page of RIMS.org and through this episode's show notes. [1:23] RIMS Virtual Workshops! RIMS has launched a new course, “Intro to ERM for Senior Leaders.” It will be held again on November 4th and 5th and will be led by Elise Farnham. [1:39] On November 11th and 12th, Chris Hansen will lead “Fundamentals of Insurance”. It features everything you've always wanted to know about insurance but were afraid to ask. Fear not; ask Chris Hansen! RIMS members always enjoy deep discounts on virtual workshops! [1:58] The full schedule of virtual workshops can be found on the RIMS.org/education and RIMS.org/education/online-learning pages. A link is also in this episode's notes. [2:09] Several RIMS Webinars are being hosted this Fall. On October 9th, Global Risk Consultants returns to deliver “Natural Hazards: A Data-Driven Guide to Improving Resilience and Risk Financing Outcomes”. [2:22] On October 16th, Zurich returns to deliver “Jury Dynamics: How Juries Shape Today's Legal Landscape”. On October 30th, Swiss Re will present “Parametric Insurance: Providing Financial Certainty in Uncertain Times”. [2:39] On November 6th, HUB will present “Geopolitical Whiplash — Building Resilient Global Risk Programs in an Unstable World”. Register at RIMS.org/Webinars. [2:51] We're very excited that today is International Podcast Day! Before we celebrate, I wanted to take a moment to acknowledge and mourn the passing of Todd Cochrane. Todd was a podcast pioneer. [3:06] I've linked in this episode's show notes to a wonderful obituary from Podnews®, about his career, starting with his time in the Navy up to launching his own podcast, and writing Podcasting: The Do It Yourself Guide, from Wiley Publishing in 2005. [3:25] Over the last couple of months, I've had the pleasure of communicating with Todd over email for the Podcast Awards, and it was only last week that I saw the unfortunate news of his passing, which occurred suddenly on September 8th. [3:30] Our condolences go out to his family, friends, and the greater podcasting industry. [3:47] On with the show! This is our special International Podcast Day episode, and I am delighted to be joined by James Swanke, the Director of the Risk Management and Insurance MBA Program at the Wisconsin School of Business at the University of Wisconsin-Madison. [4:06] Jim spent four decades at WTW, specializing in financial and strategic planning issues, as well as captive insurance company design. [4:18] Jim was recently quoted in a new professional report, available on the RIMS Risk Knowledge page, and sponsored by LineSlip Solutions, titled “The Future of Captive Insurance: Governance, Technology, and Performance Optimization.” [4:32] Jim got his start at the University of Wisconsin in broadcasting. We're going to talk about his career path and how being a disc jockey led him to where he is today, educating the next generation of risk professionals. Let's get to it! [4:50] Interview! Jim Swanke, welcome to RIMScast! [5:38] When Jim was in high school, he competed in forensics, in extemporaneous speaking. He did very well. He did well at the University of Wisconsin-Madison, and it got put in the newspaper. WLDY, in Ladysmith, Wisconsin, saw it in the newspaper and contacted him. [6:03] They were looking for a radio jock to “spin vinyls,” do some DJing, and read sports and news. That job helped Jim get into the University of Wisconsin-Madison. [6:21] Jim studied actuarial science and risk management. He went into the Bachelor's program, the MBA program, and the graduate program in risk management, insurance, and corporate finance. [6:40] Jim was hired by the Wyatt Company and did lots of feasibility studies. After 42 years at Willis Towers Watson, he retired. Now he teaches at the University of Wisconsin-Madison. [6:57] Broadcasting set Jim on his path. He says that everything about what we do in the captive and risk management area is about communication. If you're not communicating, listening, helping out, and building stuff, you're not going to be a success. [7:28] When Jim was a DJ at WLDY, they played different kinds of music. On Sundays, he played polka music. On Saturdays, it was country western, and Monday through Friday, it was rock music. Rock music is what he enjoys. At the top of every hour, he did the news and weather. [8:13] Justin recalls his own career. He was just waiting for podcasting to be invented, then he was able to make it all work out. [8:31] Jim worked with captives at Willis Towers Watson. He is quoted in a new LineSlip paper, “The Future of Captive Insurance: Governance, Technology, and Performance Optimization.” Justin saw his name there and thought it would be good to have him on RIMScast. [8:53] Jim described captives as a lifeline during extreme market conditions, comparing today's hard market to the turbulence of the 1980s. Jim tells what makes captives effective under hard conditions. Captives allow organizations to control their own destiny. [9:20] When you're in a hard market, having a captive allows you to take premiums that you normally pay to a commercial insurance carrier and put them into your captive insurance company. A captive is a subsidiary of the captive owner. [9:41] Most of the Fortune 500 companies in the United States have a captive. It allows them to arbitrage whatever's going on in the insurance marketplace. When we're having a difficult market, they put more of their premiums into the captive and rely on the captive more. [9:58] When the market softens, carriers may provide insurance at premiums that are lower than the expected losses. Organizations will buy commercial insurance all the time when the premiums are less than their projected losses. [10:14] Depending on where it is in the market, a captive has a role in an organization's risk management program. [10:27] Jim says a lot of organizations have looked to captives since 2020. We were in the midst of the pandemic, with all kinds of economic hardship. The insurance industry was in despair, as well. A lot of insurance companies cut back on the limits they were willing to offer. [10:49] Insurance companies put additional exclusions onto their insurance, so organizations had to rely on their own sophisticated ways of financing their losses. If they hadn't set up a captive, they set up a captive. If they had a captive in the past, they re-engineered it to do more. [11:15] They also used their captives to access the reinsurance marketplace. Reinsurance is insurance for insurance companies. A captive can be used as a platform to access reinsurers. [11:37] Even in difficult markets, having reinsurers involved created more competition, provided more limits, and there was more flexibility in the coverage terms. [11:48] That was when the pandemic was going on, which triggered the hardening of the market and the lack of availability of insurance. Organizations with captives relied on them and did more. Organizations without captives had captive feasibility studies done and formed captives. [12:09] Jim says the CEO of a captive should be a senior person who will monitor what's going on, fairly senior in the organization. It's not a full-time position. It takes three or four hours a month, plus board meetings. [12:46] A captive is required to have a captive manager, who is an accountant. They keep the books and interface for the captive with the regulator. The President or CEO of the captive relies on the captive manager to do a lot of the daily work. [13:09] Jim says you need a senior person involved so people take the captive seriously. The senior person is going to be the driver in reducing the severity of loss through loss prevention and loss reduction. Having a senior person is so important to the success of the captive. [13:40] There are lots of considerations when you're looking to make changes to your captive. Changes could include adding emerging types of risks, like cyber risk. If you're a hospital, a lot of medical malpractice captives have been hugely successful and have grown surplus. [14:08] Healthcare institutions are passing on some of their capitated risk exposures into their captives because they've done quite well with their medical malpractice. These risks are not correlated with each other, so there is a diversification benefit. [14:22] As you look to make these changes, you need to look at increasing risk assumptions, different attachment points on reinsurance, and changing your investment policy. You have lots of levers, and if you make changes, you need to analyze what the impact will be on your captive. [14:52] Jim talks about leaning into technology. Before 9/11, we didn't have the sophisticated software we've created in the last few years. [15:06] To look at covering all the possibilities and changing your captives, from adding new coverages to reinsurance reattachment points, was a monumental amount of actuarial work to figure out how to optimize your captive. [15:19] Recently developed software looks at all the possibilities in terms of changing your captive to optimize what you're doing. 20 years ago, Jim would spend months doing the actuarial work, working with an investment bank and charging them heavy fees. [15:39] Now, with new software, what took Jim months and months to do can be done in a matter of two to three days. The productivity today, in terms of optimizing your captive, is far greater than it was 20 years ago, because of the software that has been developed. [15:55] Jim likes that the software looks at all the risks and how these risks interact with one another. Looking at risks in a captive holistically is very important because many of these risks are hardly correlated with one another. [16:15] Looking at risks holistically, you can figure out the diversification benefit of having all of these risks within your captive, which has a major impact on the amount of economic capital that your captive will need to maintain. This software has been a game-changer. [16:34] RIMS Events! On October 1st through the 3rd, the RIMS Western Regional Conference will be held in North San Jose at the Santa Clara Marriott. The agenda is live. It looks fantastic! Visit RIMSWesternRegional.com and register today! [16:55] On November 17th and 18th, join us in Seattle, Washington, for the RIMS ERM Conference 2025. The agenda is live. Check out Episode 357 for Justin's dialogue with ERM Conference Keynote Presenter Dan Chuparkoff on AI and the future of risk. [17:14] Visit the Events page of RIMS.org to register. [17:17] RISKWORLD 2026 will be in Philadelphia, Pennsylvania, from May 3rd through May 6th. RIMS members can now lock in the 2025 rate for a full conference pass to RISKWORLD 2026 when you register by September 30th! [17:32] This also lets you enjoy earlier access to the RISKWORLD hotel block. Register by September 30th, and you will also be entered to win a $500 raffle! Do not miss out on this chance to plan and score some of these extra perks! [17:46] The members-only registration link is on this episode's show notes. If you are not yet a member, this is the time to join us! Visit RIMS.org/Membership and build your network with us here at RIMS! [17:56] If you are listening to RIMScast on our broadcast day, that means today is September 30th. It is last call for registration at the Earlybird rate! [18:08] In the spirit of it being September 30th, which is International Podcast Day, let's return to our interview with Jim Swanke! [18:22] Jim is the Director of the Risk Management and Insurance MBA at the University of Wisconsin-Madison. The curriculum includes technology, AI, and automation. In his classes, Jim is using the new software he discussed earlier. [18:46] Jim taught a class the day before on the principles of risk management. He talked about how risks are interrelated with each other and how you need to analyze them holistically, figuring out how they are correlated, not in siloes. [19:13] The holistic view will give you the best answer in terms of the economic capital that will be required to put into your captive. If you're analyzing risks silo by silo for each risk, that will lead you to having more economic capital in your captive than you need. [19:35] Jim has learned, in 42 years of consulting, that the CFOs in these organizations don't want to trap cash in their captives. Teaching this software to this new generation of students, they will be able to step into the roles of captive managers that the industry will need. [20:07] We're at the tip of the iceberg with AI. We're still learning in Academia what the power of AI is going to be. Jim foresees AI being very important in handling claims and in underwriting. [20:30] AI will allow commercial insurance companies to have a better way of doing their pricing and making decisions on whether or not risks should be accepted. It will also be beneficial to captives. [20:43] Jim thinks AI will advance the technology far ahead. We're just beginning to touch on some of the advantages within the insurance industry and within captives. [21:05] Jim started teaching in 2011. When University of Wisconsin-Madison Professor Dan Anderson retired, Jim was chosen to teach a class on sustainability that was started by Professor Anderson. He has taught it since 2011. [21:41] At the time, some students did not think anything was going on with climate change. A couple of students stood up in class and said all of this was just made up. It was a fantasy. [22:03] Today, when Jim goes into class, students are there a half-hour early and stay late. They are very connected and working together to figure out how to reduce CO2 emissions to slow down the heating of the planet and the extreme weather events that are coming more often. [22:24] The class has evolved over the years, and the students are more engaged than they ever have been. [22:33] The students from the University of Wisconsin-Madison were the winners of the Spencer-RIMS Risk Management Challenge at RISKWORLD 2025 in Chicago. Jim knows all of those students and had a couple of them in his class yesterday. [23:04] The students won with the Huntington, West Virginia case study, a six-month project. Huntington is on the Ohio River, and with extreme weather events, flooding has become a big issue in that community. They competed with students around the world to solve the issue. [23:49] Each school's team came up with things that could be done and conducted an analysis on what they thought was the best way of handling it. The University of Wisconsin-Madison's team focused on resiliency with levees and dikes to hold back the flooding. [24:27] The four Wisconsin students presented their paper and won, out of 61 schools competing. The University of Wisconsin-Madison received $10K. The second-place university, DePaul, received $7.5K, and the third-place school, IIRM Hyderabad (past year winner), got $5K. [25:04] The University of Wisconsin-Madison team entered two other contests last year and won them both. The CICA Captive competition involved case studies around Kaneka captives. It required an essay and a PowerPoint deck. [25:52] The MBA students entered the A.M. Best competition for insurance solutions to a global issue. The students used a combination of parametric and indemnity triggers to provide insurance to the disadvantaged in the Caribbean and Latin America. [26:23] If there was hurricane damage, it would trigger a parametric to allow an amount of money to be paid immediately to these disadvantaged families. Then there would be the indemnity insurance that would look at the actual losses and true them up to the loss amount. [26:49] It involved the combination of parametrics and conventional indemnity insurance, which was noteworthy and probably pushed the team over the top. [27:11] The professor who was the advisor in the Spencer Challenge is Carl Barlett. Carl is an attorney by training, and he has the energy to work with bachelor's students. He's graduated hundreds of people out of his program over the last four or five years. [27:59] The University has Career Fairs where 60 or 70 companies will come to meet with students. That's a credit to Carl. Not a lot of companies will come to a university to meet with students. Because of the program he put together, lots of organizations want to hire students. [28:21] The University of Wisconsin-Madison business school is typically ranked number 1. [28:31] A Final Break! The Spencer Educational Foundation's goal to help build a talent pipeline of risk management and insurance professionals is achieved, in part, by its collaboration with risk management and insurance educators across the U.S. and Canada. [28:50] Since 1999, Spencer has awarded over $2.9 million to create more than 570 Risk Management Internships. The Internship Grants application process is now open through October 15th, 2025. [29:06] To be eligible, risk managers must be based in the U.S., Canada, or Bermuda. A link to the Internship Grants page is in this episode's show notes. You can always visit SpencerEd.org, as well. [29:19] Let's Get Back to Our Interview with Jim Swanke of the University of Wisconsin-Madison! [29:46] Jim tells his students that we don't know today what the emerging risks are going to be. What we need to do is design our risk management program and keep our eyes and ears open to what is going to happen next. [30:04] Jim cites The Black Swan, by Nassim Nicholas Taleb. It gets into what we need to do as people of risk management and societies to try to identify the emerging risks that will impact us going forward. [30:21] In risk management, we look at the past to try to project what's going to happen in the future. We were caught by the pandemic. Very little business interruption insurance was offered. If we had been forward-thinking, we would have thought about coverages for the emerging risks. [31:19] An emerging risk after 9/11 was that insurance companies put exclusions on their insurance policies, excluding terrorism. The Federal Government passed the Terrorism Risk Insurance Act (TRIA) and offered it as a backstop to insurance companies. [31:55] Anybody with a captive could access that reinsurance through the U.S. Treasury, using their captive insurance company. [32:23] Jim sees more employee benefits going into captives. The advantages you have in the P&C area are also in place for employee benefits. Organizations with large workers' compensation self-insurance programs are putting excess workers' compensation into captives. [32:57] Jim says you need to be nimble and on your toes. Emerging risks are going to come out over the next 10 to 15 or 20 years. Keep your eyes and ears open so when they emerge, you can deal with them to reduce the frequency and severity of loss and see how to finance them. [33:19] Jim highly recommends reading The Black Swan. It's a good way to begin to think about how you should think about emerging risks. [33:42] Jim says school is going really well. One thing he noticed this year is the diverse nature of his students. There are more disciplines within the risk management area that people are interested in. [33:56] In class recently, Jim had a group that was in the investment banking area, a group that was in HR, and a couple of students from China. There was a broad diversity in the class. [34:16] It enriches the conversation to have people coming from different places with different backgrounds and different educational experiences. It shows the power of having diversity in the classroom. It's exciting. [34:32] The class will write papers on Enterprise Risk Management and talk about captives, and more. They'll compete in the CICA Captive Competition again, to maintain their number one rating there! They're off to a great start! It's nice to see students so highly energized! [34:53] Jim says the future is bright with the students graduating from the Wisconsin School of Business at the University of Wisconsin-Madison. [35:22] Justin and others have liked Jim's broadcasting voice. Jim thanks Justin for commenting on it. [35:55] Jim's time as a DJ was 50 years ago. He recalls two or three instances of hot mikes, when some of the FCC's seven deadly words may have been spoken. He says nobody wants that, but it was a real learning experience. [36:29] Jim recalls when the studio tower was hit by lightning. Jim was alone in the radio station when it happened. Lightning bolts were flying around the building after the tower got hit. The station went off the air, and Jim had to figure out a way to put it back on the air. [36:58] Jim highly recommends to young people, if you get an opportunity to get involved with radio or TV, give it a shot, because it's a lot of fun! Justin ties it to podcasting and video blogging. [37:42] Jim likes all the music of 1976 and didn't have a favorite album. He likes Deep Purple and Bob Seger. He says there's no better songwriter than Bob Seger. There was a diversity of good music going out at that time. It was a wonderful time to be working in a radio station. [38:47] Justin is a father of two young people under 12 who like to listen to classic rock. “Dancing in the Moonlight,” by King Harvest, is a greatest hit in the family. They love Van Morrison. [39:56] On the subject of podcasting, Jim thinks there is an opportunity to develop content that helps the everyday American with their personal insurances, like homeowners, auto, health, life, and how they buy their insurances. [40:45] In class recently, the MBA students, the brightest and best, designing plans for New York investment banks and worldwide financial institutions, told Jim that they had questions about what to buy in auto policies and homeowners policies. [41:07] Jim states that an insurance podcast for the everyday American is something the industry needs to be doing. Justin suggests that members of the global RIMScast audience could pick up the baton and get to work! [41:27] Maybe it becomes part of the coursework for a class like Jim's. It could be part of a challenge, like the Spencer-RIMS Risk Management Challenge. [41:48] Jim says being able to talk about this with graduate students gives them some familiarity with what risk is, in terms of the instability of results. They can relate to it because they need to buy an auto policy or a homeowners policy. [42:03] While these coverages don't match up perfectly with what's going on in the commercial insurance marketplace, learning about them gives students a sense of what insurance is about, what risk management is about, and how to reduce the frequency and severity of losses. [42:22] Jim, it has been such a pleasure to speak with you and to pick your brain on risk management education, broadcasting, and music! Thank you so much for joining us here on RIMScast! [42:33] Good luck to you and your students at the University of Wisconsin-Madison, as you look to the 2026 competitions. I can only imagine they're going to do great things! [42:58] Special thanks again to Jim Swanke for joining us here on RIMScast! For more information, check out the links in this episode's show notes. [43:06] Remember to check out “The Future of Captive Insurance: Governance, Technology, and Performance Optimization”, a Professional Report sponsored by LineSlip. It is available through the Risk Knowledge Page of RIMS.org. That link is also in this episode's show notes. [43:22] The paper features a lot of Jim's fascinating perspective and insights on captives. [43:28] Plug Time! You can sponsor a RIMScast episode for this, our weekly show, or a dedicated episode. Links to sponsored episodes are in the show notes. [43:56] RIMScast has a global audience of risk and insurance professionals, legal professionals, students, business leaders, C-Suite executives, and more. Let's collaborate and help you reach them! Contact pd@rims.org for more information. [44:14] Become a RIMS member and get access to the tools, thought leadership, and network you need to succeed. Visit RIMS.org/membership or email membershipdept@RIMS.org for more information. [44:33] Risk Knowledge is the RIMS searchable content library that provides relevant information for today's risk professionals. Materials include RIMS executive reports, survey findings, contributed articles, industry research, benchmarking data, and more. [44:48] For the best reporting on the profession of risk management, read Risk Management Magazine at RMMagazine.com. It is written and published by the best minds in risk management. [45:02] Justin Smulison is the Business Content Manager at RIMS. Please remember to subscribe to RIMScast on your favorite podcasting app. You can email us at Content@RIMS.org. [45:15] Practice good risk management, stay safe, and thank you again for your continuous support!   Links: RIMS ERM Conference 2025 — Nov. 17‒18 Spencer Internship Program — Registration Open Through Oct. 15. RIMS Western Regional — Oct 1‒3 | Bay Area, California | Registration open! RISKWORLD 2026 — Members-only early registration through Sept 30! — Last Call! RIMS-Certified Risk Management Professional (RIMS-CRMP) The Strategic and Enterprise Risk Center RIMS-CRO Certificate in Advanced Enterprise Risk Management — Featuring Instructor James Lam! Next bi-weekly course begins Oct 9. RIMS Diversity Equity Inclusion Council RISK PAC | RIMS Advocacy | RIMS Legislative Summit SAVE THE DATE — March 18‒19, 2026 RIMS Risk Management magazine | Contribute RIMS Now “The Future of Captive Insurance: Governance, Technology, and Performance Optimization” — Professional Report, Sponsored by LineSlip | Featuring insight from James Swanke University of Wisconsin-Madison Wins 2025 Spencer-RIMS Risk Management Challenge Internationalpodcastday.com Obituary for Podcasting Trailblazer Todd Cochrane RIMS Webinars: RIMS.org/Webinars “Natural Hazards: A Data-Driven Guide to Improving Resilience and Risk Financing Outcomes” | Oct. 9 | Sponsored by Global Risk Consultants “Jury Dynamics: How Juries Shape Today's Legal Landscape” | Oct. 16, 2025 | Sponsored by Zurich “Parametric Insurance: Providing Financial Certainty in Uncertain Times” | Oct. 30, 2025 | Sponsored by Swiss Re “Geopolitical Whiplash — Building Resilient Global Risk Programs in an Unstable World” | Nov. 6 | Sponsored by HUB   Upcoming RIMS-CRMP Prep Virtual Workshops: RIMS-CRMP Virtual Exam Prep — Oct. 29‒30, 2025 RIMS-CRMP-FED Exam Prep Virtual Workshop — November 11‒12 Full RIMS-CRMP Prep Course Schedule Risk Appetite Management | Oct 22‒23 | Instructor: Ken Baker Intro to ERM for Senior Leaders | Nov. 4‒5 | Instructor: Elise Farnham Fundamentals of Insurance | Nov. 11‒12 | Instructor: Chris Hansen Leveraging Data and Analytics for Continuous Risk Management (Part I) | Dec 4. See the full calendar of RIMS Virtual Workshops RIMS-CRMP Prep Workshops   Related RIMScast Episodes about Education, Risk Talent, and Captives: “Risk Management Momentum with Lockton U.S. President Tim Ryan” “RIMS 2025 Risk Manager of the Year, Jennifer Pack”   Sponsored RIMScast Episodes: “The New Reality of Risk Engineering: From Code Compliance to Resilience” | Sponsored by AXA XL (New!) “Change Management: AI's Role in Loss Control and Property Insurance” | Sponsored by Global Risk Consultants, a TÜV SÜD Company “Demystifying Multinational Fronting Insurance Programs” | Sponsored by Zurich “Understanding Third-Party Litigation Funding” | Sponsored by Zurich “What Risk Managers Can Learn From School Shootings” | Sponsored by Merrill Herzog “Simplifying the Challenges of OSHA Recordkeeping” | Sponsored by Medcor “Risk Management in a Changing World: A Deep Dive into AXA's 2024 Future Risks Report” | Sponsored by AXA XL “How Insurance Builds Resilience Against An Active Assailant Attack” | Sponsored by Merrill Herzog “Third-Party and Cyber Risk Management Tips” | Sponsored by Alliant “RMIS Innovation with Archer” | Sponsored by Archer “Navigating Commercial Property Risks with Captives” | Sponsored by Zurich “Breaking Down Silos: AXA XL's New Approach to Casualty Insurance” | Sponsored by AXA XL “Weathering Today's Property Claims Management Challenges” | Sponsored by AXA XL “Storm Prep 2024: The Growing Impact of Convective Storms and Hail” | Sponsored by Global Risk Consultants, a TÜV SÜD Company “Partnering Against Cyberrisk” | Sponsored by AXA XL “Harnessing the Power of Data and Analytics for Effective Risk Management” | Sponsored by Marsh “Accident Prevention — The Winning Formula For Construction and Insurance” | Sponsored by Otoos “Platinum Protection: Underwriting and Risk Engineering's Role in Protecting Commercial Properties” | Sponsored by AXA XL “Elevating RMIS — The Archer Way” | Sponsored by Archer   RIMS Publications, Content, and Links: RIMS Membership — Whether you are a new member or need to transition, be a part of the global risk management community! RIMS Virtual Workshops On-Demand Webinars RIMS-Certified Risk Management Professional (RIMS-CRMP) RISK PAC | RIMS Advocacy RIMS Strategic & Enterprise Risk Center RIMS-CRMP Stories — Featuring RIMS President Kristen Peed!   RIMS Events, Education, and Services: RIMS Risk Maturity Model®   Sponsor RIMScast: Contact sales@rims.org or pd@rims.org for more information.   Want to Learn More? Keep up with the podcast on RIMS.org, and listen on Spotify and Apple Podcasts.   Have a question or suggestion? Email: Content@rims.org.   Join the Conversation! Follow @RIMSorg on Facebook, Twitter, and LinkedIn.   About our guest: James Swanke, Lecturer: Risk and Insurance at the University of Wisconsin-Madison's Wisconsin School of Business, Director of the Risk Management and Insurance MBA program Production and engineering provided by Podfly.  

Today on the radio show. 1 - Smoko chat. New Simpsons Movie. 4 - Weirdest thing in your house. 8 - Pointless Declines. Waste of time. 11 - What is a waste of your time? 14 - Dunc’s Gingernut dessert. 15 - Cutting sugar out for 15 days. 20 - Oasis documentary coming out soon. 23 - One Plum Hotline 27 - Guess these words. 30 - Great advice for shitty people. 33 - Laughable injuries. 37 - Huntington's disease. 41 - Late mail. 44 - Last drinks. Get in touch with us: https://linktr.ee/therockdrive

In a world of survivors, Huntington resident Eloise Hughes Smith stands out. The daughter of a Congressman and one of the nation's most politically influential families, Eloise married Lucian Smith of Morgantown and their honeymoon would end on that cold night with the sinking of the Titanic. YouTube: https://www.youtube.com/watch?v=zTWHhrJM4c0

Researchers say they have, for the first time, dramatically slowed the progression of a cruel and devastating neuron condition called Huntington’s disease.For sufferers, this potentially means getting years of their life back or the lessening of symptoms of a condition that robs them of physical movement and kills their brain cells.Today, Professor Julie Stout from Monash University’s Turner Institute of Brain and Mental Health, on why this clinical trial, which involved a small number of patients in London, has the medical world so excited.Subscribe to The Age & SMH: https://subscribe.smh.com.au/See omnystudio.com/listener for privacy information.

Researchers say they have, for the first time, dramatically slowed the progression of a cruel and devastating neuron condition called Huntington’s disease.For sufferers, this potentially means getting years of their life back or the lessening of symptoms of a condition that robs them of physical movement and kills their brain cells.Today, Professor Julie Stout from Monash University’s Turner Institute of Brain and Mental Health, on why this clinical trial, which involved a small number of patients in London, has the medical world so excited.Subscribe to The Age & SMH: https://subscribe.smh.com.au/See omnystudio.com/listener for privacy information.

Öll viðtölin úr þætti dagsins ásamt símatíma: Sigurður Þ. Ragnarsson, Siggi Stormur um fyrstu haustlægðina Halla Hrund Logadóttir þingkona Framsóknarflokksins og fyrrverandi orkumálastjóri um olíubirgðir Símatími Jón Gnarr, þingmaður Viðreisnar um ættarnöfn Grétar Þór Eyþórsson prófessor í stjórnmálafræði við Háskólann á Akureyri um borgarpólitíkina Helga Eyjólfsdóttir öldrunarlæknir um evrópska öldrunarlæknaþingið í Hörpu Gunnhildur Sif Oddsdóttir formaður HD samtakanna um nýja meðferð við Huntington sjúkdómnum sem vekur vonir Sóley Tómasdóttir kynja- og fjölbreytileikaráðgjafi

For the first time ever, a successful treatment has been found for the devastating brain disease, Huntington's. The inherited condition, which resembles a combination of dementia, Parkinson's and motor neurone disease, affects hundreds of thousands of people in the US and Europe. The scientists who developed the new gene therapy, and people who have the disease, say its a huge breakthrough that could give people a better quality of life for decades.Also: we meet the teacher who's launched a Happiness Project to help her pupils learn about what really matters, and is encouraging others to do the same. We find out about the small actions that have transformed how people feel about a living in a huge public housing complex in Mumbai, bringing a true sense of community. It's Fat Bear Week in Alaska - a time to celebrate weight gain as the beautiful inhabitants of Katmai National Park prepare to hibernate. Plus a new way to bring more poetry into your life; the dogs getting to swim in German public pools; and the man cycling hundreds of miles dressed as a paramedic gorilla. Our weekly collection of inspiring, uplifting and happy news from around the world.Presenter: Oliver Conway. Music composed by Iona Hampson

Send us a textAfter a two-week hiatus dealing with shipping challenges and postal strikes, Jason and Chris return with exciting scientific breakthroughs and heartwarming pet insights. Their absence was filled with stuffy reshipping adventures and a memorable Comic-Con appearance with their super-dog companions.The episode features a remarkable development in Huntington's disease treatment – a devastating neurodegenerative condition affecting 7 in 100,000 people worldwide. A pioneering gene therapy trial using microRNA delivered via viral vectors directly to the brain has shown unprecedented success in slowing disease progression. Patients receiving the highest dose demonstrated 75% less decline in cognitive and motor symptoms compared to untreated individuals. While invasive and still pending regulatory approval, this breakthrough offers genuine hope for patients and families who've endured decades of despair. Beyond Huntington's, this approach could potentially revolutionize treatments for other neurodegenerative diseases like Parkinson's.The pet science segment reveals fascinating research about canine cognition, particularly how "gifted" dogs mentally categorize toys by function rather than appearance. Border collies demonstrated an ability to classify toys based solely on how they're used in play – whether for throwing or tugging – without relying on verbal cues. This suggests dogs possess cognitive flexibility comparable to human toddlers, understanding not just words but concepts. The study highlights how our canine companions don't merely memorize but actually comprehend and apply knowledge functionally, raising profound questions about their cognitive abilities.Our all links to social media and more!Support the showFor Science, Empathy, and Cuteness!Being Kind is a Superpower.https://twitter.com/bunsenbernerbmd

On today's show:, scientists successfully treat Huntington's disease for the first time, slowing the disease by at least 75%: we hear how they've done it. Also, the High Seas Treaty takes a step closer to protecting the world's oceans. And the Earth-sized planet not that far away that might have conditions suitable for life. Like this podcast? Please help us by supporting the Naked Scientists

Ha pasado más de una década desde la desaparición de los estudiantes de la Escuela Normal Rural de Ayotzinapa, y hoy, como cada año desde 2014, los familiares de los estudiantes exigieron a las autoridades que den información sobre el paradero de sus hijos y pidieron justicia para ellos.Donald Trump firmó un decreto para que TikTok siga operando en Estados Unidos si cumple con una transacción que valúa a la empresa en unos 14 mil millones de dólares.Además… XXXXXXXXX; Este domingo 28 de septiembre, se conmemora el Día de Acción Global por el Aborto Legal, Seguro y Accesible; Banxico volvió a recortar la tasa de interés, dejándola en 7.50%; El ejército israelí bombardeó varios sitios en toda la capital de Yemen; El expresidente francés Nicolas Sarkozy, fue sentenciado a cinco años de prisión por conspiración criminal; Y ya sabemos quiénes serán las mascotas para la Copa del Mundo 2026.Y para #ElVasoMedioLleno… Un grupo de científicos logró desacelerar el avance de la enfermedad de Huntington en un ensayo clínico. Para enterarte de más noticias como estas, síguenos en redes sociales. Estamos en todas las plataformas como @telokwento. Hosted on Acast. See acast.com/privacy for more information.

The CDC recommends changes to MMRV vaccine use; Trump administration claims acetaminophen linked to autism; first Barth syndrome treatment gets green light; gene therapy looks promising for Huntington disease; and a new SC formulation of Keytruda gains approval.

Join Opie and the crew for a wild, unfiltered episode of Opie Radio broadcast live from Gebhardt's! The gang dives into hilarious rants about AI marrying humans, healthcare gripes, and a chaotic rock trivia showdown that tests their music knowledge with questions on Bob Dylan, Billy Joel, and more. From debates about dandruff to tales of mattresses and motorbikes, this episode is packed with laughs, barbs, and unexpected tangents. Plus, hear about a touching moment tied to Huntington's disease and the latest on alien meteors. Tune in for a rowdy, beer-fueled hangout with Opie, Ron, Matt, and Chris Ferretti. Cheers to Southern Tier's Oktoberfest brew!

A gunman killed a detainee and wounded two others at an ICE detention facility in Dallas. The Dallas Morning News spoke to eyewitnesses about the incident. Noah Robertson, national-security reporter covering Congress for the Washington Post, breaks down how Trump plans to shift $2 billion designated for foreign aid to priorities that fit the White House agenda. Protests led by Gen Z in Nepal over corruption and a social-media crackdown turned deadly, costing 74 people their lives and the prime minister his job. The Wall Street Journal’s Gabriele Steinhauser joins to discuss the violence and how similar protests have been seen in other countries. Plus, a super typhoon wrecked havoc across Asia, Jimmy Kimmel’s return racked up big numbers online, and a potentially major breakthrough in treatment for Huntington’s disease. Today’s episode was hosted by Shumita Basu.

Former French president Nicolas Sarkozy has been sentenced to five years in jail after being found guilty of criminal conspiracy in a case related to millions of euros of illicit funds from the late Libyan leader Col Muammar Gaddafi. Also on the programme: the havoc caused by drones closing airspace and airports in Denmark; and the musician Arlo Guthrie - whose family has been wrecked by Huntington's disease - on the promise of this week's medical breakthrough. (Photo: Former French President Nicolas Sarkozy arrives for the verdict in his trial at the courthouse in Paris. Credit: Reuters)

Jen and Frank chat about the oft-mentioned year of 1992 and their two nostalgic trips to Walt Disney World. On this episode…

Today on The Drive with Paul Swann, Paul talks with Wayne Ryan, Executive Director of the WVSSAC, about the major move the commission's making—awarding the West Virginia state high school baseball tournament to Jack Cook Field in Huntington (2026–2028, with an option for 2029) and the expansion of the tournament from 4 to 8 teams per class. 

Orla Hardiman, Professor of Neurology at Trinity College and Consultant Neurologist at Beaumont Hospital in Dublin, reacts to a new trial showing success in treating Huntington's Disease

This is a recap of the top 10 posts on Hacker News on September 24, 2025. This podcast was generated by wondercraft.ai (00:30): Yt-dlp: Upcoming new requirements for YouTube downloadsOriginal post: https://news.ycombinator.com/item?id=45358980&utm_source=wondercraft_ai(01:51): That Secret Service SIM farm story is bogusOriginal post: https://news.ycombinator.com/item?id=45357693&utm_source=wondercraft_ai(03:13): Terence Tao: The role of small organizations in society has shrunk significantlyOriginal post: https://news.ycombinator.com/item?id=45362697&utm_source=wondercraft_ai(04:34): Just let me select textOriginal post: https://news.ycombinator.com/item?id=45360475&utm_source=wondercraft_ai(05:56): Everything that's wrong with Google Search in one imageOriginal post: https://news.ycombinator.com/item?id=45366566&utm_source=wondercraft_ai(07:17): US airlines are pushing to remove protections for passengers and add more feesOriginal post: https://news.ycombinator.com/item?id=45359378&utm_source=wondercraft_ai(08:39): Baldur's Gate 3 Steam Deck – Native VersionOriginal post: https://news.ycombinator.com/item?id=45354644&utm_source=wondercraft_ai(10:00): EU age verification app not planning desktop supportOriginal post: https://news.ycombinator.com/item?id=45359074&utm_source=wondercraft_ai(11:22): Huntington's disease treated for first timeOriginal post: https://news.ycombinator.com/item?id=45358940&utm_source=wondercraft_ai(12:43): My game's server is blocked in Spain whenever there's a football match onOriginal post: https://news.ycombinator.com/item?id=45358433&utm_source=wondercraft_aiThis is a third-party project, independent from HN and YC. Text and audio generated using AI, by wondercraft.ai. Create your own studio quality podcast with text as the only input in seconds at app.wondercraft.ai. Issues or feedback? We'd love to hear from you: team@wondercraft.ai

In this episode, host Sandy Vance sits down with Henry O'Connell, Co-Founder & CEO of Canary Speech, to explore how voice AI is transforming healthcare. Canary Speech is pioneering vocal biomarker technology—using subtle patterns in speech to replace subjective assessments with objective, actionable data.From measuring pain levels to aiding in the diagnosis of conditions like Anxiety, depression, Huntington's, Parkinson's, MCI, Canary's tools are designed to improve accuracy and speed in healthcare decision-making. This innovation not only helps patients receive the right care faster, but also supports nurses and clinicians by reducing burnout, improving workplace safety, and streamlining workflows.If you're curious about the future of AI in healthcare, digital health innovation, or how speech analysis can change the way we approach diagnostics and patient care, this conversation is packed with insights you won't want to miss.In this episode, they talk about:Addressing the growing challenge of aggression in healthcare settingsMeasuring ROI while reducing risk, preventing burnout, and improving employee retentionUsing voice AI to assist in diagnosing ADHD, autism, and scaling pain assessmentsUpcoming projects at Canary Speech, including collaboration with Microsoft's Dragon softwareHelping providers deliver more empathetic, patient-centered careFast implementation! Canary can be deployed in days, not weeks, for new clientsA Little About Henry:Henry O'Connell is the CEO and co-founder of Canary Speech, a leading AI health tech company using real-time vocal biomarkers to screen for mental health and neurological conditions. With over two decades of experience in technology leadership, including roles at Hewlett-Packard, Gilson, and the NIH, he has served on the boards of multiple tech companies globally. A passionate advocate for voice technology in healthcare, O'Connell regularly speaks on the transformative potential of AI and vocal biomarkers to improve disease detection, patient monitoring, and clinical decision-making. He aims to provide health screening that is accessible, objective, and scalable.

In this rare and candid conversation, Todd Chrisley sits down with Billy Marshall, Director of the Bureau of Prisons (BOP). Together, they open up about life inside the prison system, the realities of incarceration, and what change might look like from both personal and institutional perspectives.This interview goes beyond headlines to explore Todd's personal experience serving time in the federal prison system, Billy Marshall's role leading the BOP and overseeing federal corrections, and honest discussions about reform, accountability, and the future of corrections in America.Whether you've followed Todd's story from the start or you're interested in learning more about how the federal prison system really works, this conversation gives insight you won't hear anywhere else.THANK YOU TO OUR SPONSORS!- Cowboy Colostrum: Visit www.cowboycolostrum.com and get 25% OFF your entire order when you use code CHRISLEY at checkout! #CowboyColostrumPod- Clean Safe Products: Go to www.cleansafeproducts.com/CHRISLEY today to get $15 OFF the Green Mitt Kit, the world's easiest soft surface cleaning solution!- Jones Road Beauty: Use code CHRISLEY at www.jonesroadbeauty.com to get a Free Cool Gloss with your first purchase! #JonesRoadBeauty #ad- Just Thrive: Go to www.justthrivehealth.com/CONFESSIONS to save 20%! Take the 90-Day Just Thrive Challenge today because when your gut thrives, you thrive!- Genesis Gold Group: Visit www.chrisleylovesgold.com today for your FREE Family Wealth Protection Gold Guide and join thousands of Americans who've protected their legacy with real assets!- Superpower: Go to www.superpower.com to learn more and lock in the special $199 price while it lasts. Live up to your 100-Year potential. #superpowerpodFOLLOW US ON SOCIALS:Todd Chrisley:Insta: (https://www.instagram.com/toddchrisley)Facebook: (https://www.facebook.com/toddchrisley)Julie Chrisley:Instagram: (https://www.instagram.com/juliechrisley)Facebook: (https://www.facebook.com/JulieChrisley)Chrisley Confessions 2.0:Instagram: (https://www.instagram.com/chrisleyconfessions2.0)TikTok: (https://www.tiktok.com/@chrisleyconfessions2.0)YouTube: (https://www.youtube.com/@ChrisleyConfessions)Produced and Edited by: The Cast Collective (Nashville, TN)YouTube: (https://www.youtube.com/@TheCastCollective)Instagram: (https://www.instagram.com/thecastcollective)TikTok: (https://www.tiktok.com/@castcollective)About Billy Marshall:William K. Marshall III is the Director of the Federal Bureau of Prisons (BOP). Director Marshall was sworn in on April 21, 2025, and assumed responsibility for the operation of 122 BOP facilities, six regional offices, two staff training centers, and 22 residential reentry management offices. He is responsible for the oversight and management of approximately 36,000 staff members and 156,000 federal inmates.Director Marshall began his law enforcement career with the West Virginia State Police in Huntington, where he was honored as the 1995 National Association of Police Organizations West Virginia Police Officer of the Year. He transferred to the Interstate Drug Interdiction Team and worked with the West Virginia Worker's Compensation Fraud Task Force, as well as on drug task forces in Charleston and Parkersburg. His exemplary service led to his selection for the IRS Criminal Investigation Division's Fraud Task Force, working out of the U.S. Attorney's Office for the Southern District of West Virginia in Charleston, during which time he also received a deputation from the U.S. Marshals Service.Promoted to Sergeant in 2006, Director Marshall later became the Commander of the Pleasants County Detachment before serving as Commander of the Wood County Detachment. He was then selected as the Deputy Director of Traffic Records at State Police Headquarters, where he collaborated with the Governor's Highway Safety Program. In 2010, Director Marshall returned to Wood County to resume command until his retirement in July 2017, concluding more than 25 years of service with the West Virginia State Police.Following his retirement, Director Marshall was appointed as the first Director of Corrections Investigations for the West Virginia Department of Military Affairs and Public Safety (now known as the West Virginia Department of Homeland Security). He was also designated the Director of the Division of Juvenile Services. Under the newly formed Division of Corrections and Rehabilitation, he served as Assistant Commissioner of the Bureau of Juvenile Services until Governor Jim Justice appointed him as the Commissioner of the West Virginia Division of Corrections and Rehabilitation in January 2023.Director Marshall earned his undergraduate degree from Marshall University and is a graduate of the West Virginia State Police Academy.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Russia hits back at the US President Donald Trump, after he called the nation a 'paper tiger'. The Kremlin spokesman Dmitry Peskov said 'Russia is generally associated with a bear. There are no paper bears. Russia is a real bear.' We unpack the importance of words in the US-Russia relationship and whether President Trump's comments will have any impact on the ground in Ukraine. As Syria's interim President, Ahmed Al Sharaa, addresses the United Nations General Assembly, Syrians in Damascus give us their opinion. Also: Super Typhoon Ragasa causes chaos in southern China, a landmark deal to slash the price of injectable HIV prevention drugs, and a breakthrough in treating Huntington's disease. Plus: Denmark's prime minister apologises to the victims of a forced contraceptive programme in Greenland and Jimmy Kimmel's late night show returns to our screens, after being suspended by ABC. The Global News Podcast brings you the breaking news you need to hear, as it happens. Listen for the latest headlines and current affairs from around the world. Politics, economics, climate, business, technology, health – we cover it all with expert analysis and insight.Get the news that matters, delivered twice a day on weekdays and daily at weekends, plus special bonus episodes reacting to urgent breaking stories. Follow or subscribe now and never miss a moment.Get in touch: globalpodcast@bbc.co.uk

Typhoon Ragasa has made landfall in southern China, where nearly two million people have been evacuated in preparation for its arrival.It comes after authorities said at least 17 people had been killed and more missing in Taiwan after a lake burst on Tuesday, causing severe flooding in the island's east. We hear from a reporter in TaiwanAlso in the programme: Syria's interim president is due to address the UN General Assembly, making him the first Syrian head of state to do so in nearly 60 years; and for the first time, doctors have used gene therapy to significantly slow the progression of the deadly, degenerative disease Huntington's.[Photo shows a drone view of buildings and fields submerged in flood waters in Guangfu, Hualien County, Taiwan on 24 September 2025. Credit: The Warthog Air Squadron/Reuters)

The results of a new gene therapy for Huntington's Disease are so promising that, when he saw them, one researcher tells us he thought he was dreaming. The U.S. government is spreading extremely dubious information about the causes of autism -- when a mother of two children with autism tells us what they need most is acceptance. A human rights advocate tells us Israel's closure of the only gateway from the Occupied West Bank to the outside world risks penning Palestinians in -- and is deepening fears about what might be next. The late Louise Vincent used lessons from her own life in her work as a harm reduction advocate and researcher. A friend tells us she never claimed to be in recovery, and never apologized for using. A young artist defends the dominance of a trio of brothers who are so good at painting, they just can't stop winning the annual U-S Federal Duck Stamp Art Contest -- despite a push to clip their wings.Music teachers in movies strike a chord with all of us -- but according to a new study, their miraculous methods make it harder for their real-life counterparts.As It Happens, the Wednesday Edition. Radio that knows how to find out how good a music teacher is: just inquire in choir.

Doctors have made a huge breakthrough in tackling the genetic disorder Huntington's disease, with initial results showing a significant slowing in the progress of the condition.Plans to extend the high-speed rail network between Liverpool and Manchester have been delayed and won't now be announced at the Labour Conference.The Mayor of London, Sir Sadiq Khan, has accused President Trump of being Islamophobic, after Mr Trump told world leaders at the United Nations that he thought London's mayor wanted to "go to sharia law".And how four astronauts heading on a trip around the Moon as early as February next year hope to see things no human eye has seen before.

President Trump has claimed that consuming Tylenol, or paracetamol, whilst pregnant can increase the risk of autism in children; Claudia is joined by Professor of Clinical Epidemiology Laurie Tomlinson to fact-check this unproven statement.Also on the show, BBC's Philippa Roxby joins Claudia to share a breakthrough in treating Huntington's disease. In a medical first doctors have used gene therapy to slow the progression of this fatal genetic disorder where a patient's movement, thinking, and mood deteriorates over time. Reporter Carrim Mpaweni explores how Malawi is currently dealing with Cholera, and the role climate change is playing in exacerbating outbreaks of the disease.Plus, how South Korean researchers are exploring the use of glue guns as a way to repair broken bones. Presenter: Claudia Hammond Producer: Hannah Robins Assistant Producer: Katie TomsettImage Credit: Francis Chung/Politico/Bloomberg via Getty Images

Marshall will host the WVSSAC State Baseball Tournament starting in 2026. Andrew Brown, Senior Associate AD for Capital Projects & Championship Facilities, joined Paul Swann to talk about what it means for the Herd and the community.

#WDRadio Week of Sept 21, 2025: When desperate believers sold everything they owned to follow self-proclaimed prophets promising salvation, they discovered a horrifying truth: the line between divine vision and madness was written in poison, prison bars, and the hangman's noose. From miracle eggs inscribed with holy messages to a 65-year-old virgin claiming to carry the Messiah, this is the disturbing pattern of religious mania that swept through the 19th century, leaving thousands betrayed and broken in its wake.==========HOUR ONE: Claiming to audibly hear from God either makes you crazy, or a prophet – and only time can tell which is true. If you claim things are going to happen because God says they will – and then they don't happen – that means you're cray cray, and a false prophet. That also makes your followers a bunch of dupes. Sadly, the 19th and 20th centuries were full of crazy false prophets with mindless sheep worshipping them. (Creating False Prophets) *** Headline: “Exciting Wake!” When you see the words “exciting” and “wake” in the same headline, you can make a guess that someone is not resting in peace! (Exciting Wake)==========HOUR TWO: “The Witching Hour of 3AM” *** You don't have to go to a cemetery or haunted house to experience the supernatural. You don't need to drive a cursed road to encounter a ghost. Sometimes the paranormal takes place on military bases. (The Military And The Mysterious) *** The corpse of a murderer winds up doing advertising for a drug store. (The Murder of Maggie Walker) *** In 1922, an otherwise unremarkable farmhouse in Novia Scotia was the site of alleged poltergeist activity which made headlines all over Canada and the United States. A poltergeist that liked to set fires. (The Fire Spook of Caledonia Mills)==========SUDDEN DEATH OVERTIME: A smitten fan falls in love with a talented actress, and convinces himself she loves him in return. This sounds very much like a story out of today's entertainment magazines – but this tale of unrequited love took place in the 1880's. (The Lunatic James Dougherty) *** The terrifying Aswang is the most feared creature of Philippine folklore—and with good reason. I'll tell you why. (The Deadly Aswang) ** Reports have been coming in from people claiming to see full-sized African lions not in the Savannah or in the wilderness – but in North America. But is there any truth to the their claims? (Phantom Lions of North America)==========SOURCES AND REFERENCES FROM TONIGHT'S SHOW:BOOK: “Mysterious America” by Loren Coleman: https://amzn.to/3lZIviBBOOK: “Creatures of Philippine Lower Mythology”: https://amzn.to/3m2Re3kDOCUMENTARY: “The Aswang Phenomenon”: https://amzn.to/3jQrNjC“Creating False Prophets” by Dr. Romeo Vitelli for Providentia: https://tinyurl.com/y5bqt97p,https://tinyurl.com/y26vpmga, https://tinyurl.com/y6tgpcl3, https://tinyurl.com/y2jy3eqf“Phantom Lions of North America” by Brent Swancer for MysteriousUniverse.com: https://tinyurl.com/yygdg3eh“Exciting Wake” from the Huntington, IN “Daily Democrat”, reposted on the Strange Company website: https://tinyurl.com/y5cy4ksa“The Deadly Aswang” by Professor Geller for Mythology.net: https://tinyurl.com/yxhcrcxc“The Witching Hour of 3AM” from Paranormality Magazine“The Fire Spook of Caledonia Mills” by Hammerson Peters for MysteriesOfCanada.com: https://tinyurl.com/y43ug999“The Lunatic James Dougherty” by Robert Wilhelm for MurderByGaslight.com: https://tinyurl.com/yxkxo8b6“The Military and the Mysterious” by Brent Swancer for MysteriousUniverse.org: https://tinyurl.com/y46jdmks“The Murder of Maggie Walker” posted on the website Murders In History: https://tinyurl.com/y2qw2rup==========(Over time links seen above may become invalid, disappear, or have different content. I always make sure to give authors credit for the material I use whenever possible. If I somehow overlooked doing so for a story, or if a credit is incorrect, please let me know and I will rectify it in these show notes immediately. Some links included above may benefit me financially through qualifying purchases.)=========="I have come into the world as a light, so that no one who believes in me should stay in darkness." — John 12:46==========WeirdDarkness® is a registered trademark. Copyright ©2025, Weird Darkness.

From the archive: This episode was originally recorded and published in 2022. Our interviews on Entrepreneurs On Fire are meant to be evergreen, and we do our best to confirm that all offers and URL's in these archive episodes are still relevant. Robert Huntington is CEO of Metric Collective, a vertically integrated franchise and technology company. Before Metric he was a BCG consultant, teacher, 50M dollars P and L manager and franchise executive. Top 3 Value Bombs 1. Once you've already proven that you can execute the model, that's when you can start innovating the model. 2. If you have good union economics - if you have something that customers need - and the market is growing, then franchising can be a really attractive route. 3. Franchising means you're in business for yourself - not by yourself. Fill out the lead form and let's chat about franchising - Metric Collective Sponsors HighLevel - The ultimate all-in-one platform for entrepreneurs, marketers, coaches, and agencies. Learn more at HighLevelFire.com. Gelt - Your year-round tax partner built for entrepreneurs, business owners, investors, and high net-worth individuals who want to keep more of what they earn. Get a personalized consultation and 10 percent off your first year when you mention Entrepreneurs on Fire. Visit JoinGelt.com/eof. Public - Build a multi-asset portfolio of stocks, bonds, options, crypto, and more. Go to Public.com/fire to fund your account in five minutes or less. All investing involves the risk of loss, including loss of principal. Brokerage services for US-listed, registered securities, options and bonds in a self-directed account are offered by Public Investing, Inc., member FINRA and SIPC. Public Investing offers a High-Yield Cash Account where funds from this account are automatically deposited into partner banks where they earn interest and are eligible for FDIC insurance; Public Investing is not a bank. Cryptocurrency trading services are offered by Bakkt Crypto Solutions, LLC (NMLS ID 1890144), which is licensed to engage in virtual currency business activity by the NYSDFS. Cryptocurrency is highly speculative, involves a high degree of risk, and has the potential for loss of the entire amount of an investment. Cryptocurrency holdings are not protected by the FDIC or SIPC. Alpha is an experimental AI tool powered by GPT-4. Its output may be inaccurate and is not investment advice. Public makes no guarantees about its accuracy or reliability - verify independently before use. Rate as of 6/24/25. APY is variable and subject to change. Terms and Conditions apply.