Podcasts about American Journal

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Play Episode Listen Later Jun 11, 2026 30:17

What if one of the most powerful medicines for longevity, resilience, happiness, cognitive health, and disease prevention wasn't found in a supplement, a prescription, or a cutting-edge biohack—but in the people around you? In this powerful solo episode, Darin Olien dives into one of the most overlooked health crises of our time: loneliness. Drawing from the landmark 85-year Harvard Adult Development Study, the U.S. Surgeon General's loneliness epidemic report, Blue Zones research, neuroscience, and evolutionary biology, Darin reveals why meaningful human connection may be one of the strongest predictors of health and longevity ever discovered. From oxytocin, cortisol, inflammation, vagal tone, and nervous system regulation to suburban design, social media, and the collapse of community structures, Darin exposes the hidden biological costs of isolation—and offers a practical roadmap for rebuilding the human connections we were biologically designed to need. What You'll Learn The stunning findings from Harvard's 85-year Adult Development Study Why relationships outperform wealth, genetics, diet, and exercise as predictors of well-being How loneliness increases the risk of premature death, dementia, heart disease, and stroke Why social isolation creates measurable biological stress responses The role of oxytocin in lowering inflammation and regulating stress How human connection affects the autonomic nervous system Why Blue Zone communities consistently prioritize social connection The biological difference between digital interaction and real human presence How modern architecture and technology contribute to loneliness Why community is a biological necessity—not a luxury Practical ways to rebuild meaningful relationships today How connection may be one of the most powerful health interventions available Chapters 00:00:00 – Welcome to SuperLife 00:00:33 – Sponsor: Bite Toothpaste and reducing plastic waste 00:02:49 – The most powerful health study ever conducted 00:03:01 – Harvard follows 724 people for 85 years 00:03:40 – The surprising predictor of a long, healthy life 00:04:00 – Why relationships beat wealth, genetics, diet, and exercise 00:04:42 – The Surgeon General's loneliness epidemic warning 00:05:19 – Introducing the medicine you're not taking 00:05:53 – The health benefits of genuine community 00:06:21 – The fatal convenience of modern life 00:06:47 – Replacing human connection with digital connection 00:07:12 – Why modern convenience may be creating isolation 00:07:23 – Social isolation and premature mortality 00:08:02 – Loneliness and the equivalent of smoking 15 cigarettes a day 00:08:43 – Increased risks of heart disease, stroke, and dementia 00:09:10 – Why loneliness is a biological threat 00:09:52 – The science behind social isolation 00:10:11 – Sponsor: Manna Vitality 00:12:06 – Humans as the most socially dependent species 00:12:53 – Why connection regulates the nervous system 00:13:29 – The autonomic nervous system and social safety 00:13:56 – The brain's constant question: Am I safe? 00:14:03 – The biology of belonging 00:14:24 – The ventral vagal state explained 00:14:55 – Why connection creates measurable physiological changes 00:15:03 – What happens when isolation becomes chronic 00:15:52 – Oxytocin: far more than the "love hormone" 00:16:20 – Eye contact, touch, meals, and human bonding 00:16:42 – How oxytocin lowers stress and inflammation 00:17:04 – Why no supplement can replace connection 00:17:17 – The pharmacology of authentic human moments 00:18:06 – Free medicine hidden in plain sight 00:18:39 – Dan Buettner and the Blue Zones 00:19:29 – What the world's longest-lived populations have in common 00:19:36 – Okinawa's lifelong friendship circles 00:20:08 – Sardinia's active elders and social roles 00:20:40 – Greece's culture of connection and communal meals 00:21:03 – Why longevity wasn't hacked—it was lived 00:21:38 – Social connection as the foundation of daily life 00:22:01 – The shocking decline in face-to-face interaction 00:22:21 – Young people losing 70% of in-person social time 00:22:58 – How community was systematically dismantled 00:23:00 – Robert Putnam's Bowling Alone 00:23:49 – Doing life together versus doing life alone 00:24:05 – How suburban design creates isolation 00:24:49 – The built environment shapes human behavior 00:24:55 – Social media and the promise of connection 00:25:20 – Why digital connection fails biologically 00:25:33 – Social comparison, anxiety, and nervous system stress 00:25:49 – More connected online, more isolated in reality 00:26:03 – A call to action: treating relationships like health practices 00:27:00 – Practical ways to rebuild community 00:28:00 – Prioritizing people over convenience 00:29:00 – Deep conversations, presence, and intentional connection 00:30:00 – Reclaiming community in modern life 00:31:00 – Final thoughts on connection, belonging, and health 00:31:53 – Closing remarks and outro Thank You to Our Sponsors Bite Toothpaste: Go to trybite.com/DARIN20 or use code DARIN20 for 20% off your first order Manna Vitality: Go to mannavitality.com/ and use code DARIN12 for 12% off your order. Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only $7.49/month at https://patreon.com/darinolien Find More from Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness Key Takeaway "The longest-running study in human history reached a conclusion that should fundamentally change how we think about health: the quality of our relationships predicts our happiness, resilience, and longevity more than almost anything else. Human connection isn't a luxury, a personality trait, or a nice bonus when life slows down. It is biology. It is medicine. And in a world increasingly designed for isolation, rebuilding community may be one of the most important health decisions we ever make." Bibliography/Sources: Primary Research — Loneliness, Social Isolation & Health Associated Press. (2023, May 2). Surgeon general: Loneliness poses health risks as deadly as smoking. PBS NewsHour. https://www.pbs.org/newshour/health/surgeon-general-loneliness-poses-health-risks-as-deadly-as-smoking Cacioppo, J. T., & Hawkley, L. C. (2009). Perceived social isolation and cognition. Trends in Cognitive Sciences, 13(10), 447–454. https://doi.org/10.1016/j.tics.2009.06.005 Holt-Lunstad, J., Smith, T. B., & Layton, J. B. (2010). Social relationships and mortality risk: A meta-analytic review. PLoS Medicine, 7(7), e1000316. https://doi.org/10.1371/journal.pmed.1000316 Office of the Surgeon General. (2023). Our epidemic of loneliness and isolation: The U.S. Surgeon General's advisory on the healing effects of social connection and community. U.S. Department of Health and Human Services. https://www.hhs.gov/sites/default/files/surgeon-general-social-connection-advisory.pdf Waldinger, R. J., & Schulz, M. S. (2010). What's love got to do with it? Social functioning, perceived health, and daily happiness in married octogenarians. Psychology and Aging, 25(2), 422–431. https://doi.org/10.1037/a0019087 Neuroscience — Oxytocin, Polyvagal Theory & Community Biology Carter, C. S. (1998). Neuroendocrine perspectives on social attachment and love. Psychoneuroendocrinology, 23(8), 779–818. https://doi.org/10.1016/S0306-4530(98)00055-9 Eisenberger, N. I., & Lieberman, M. D. (2004). Why rejection hurts: A common neural alarm system for physical and social pain. Trends in Cognitive Sciences, 8(7), 294–300. https://doi.org/10.1016/j.tics.2004.05.010 Heinrichs, M., Baumgartner, T., Kirschbaum, C., & Ehlert, U. (2003). Social support and oxytocin interact to suppress cortisol and subjective responses to psychosocial stress. Biological Psychiatry, 54(12), 1389–1398. https://doi.org/10.1016/S0006-3223(03)00465-7 Porges, S. W. (2011). The polyvagal theory: Neurophysiological foundations of emotions, attachment, communication, and self-regulation. W. W. Norton & Company. https://wwnorton.com/books/9780393707007 Blue Zones Research Buettner, D., & Skemp, S. (2016). Blue Zones: Lessons from the world's longest lived. American Journal of Lifestyle Medicine, 10(5), 318–321. https://doi.org/10.1177/1559827616637066 Kreouzi, M., Theodorakis, N., & Constantinou, C. (2022). Lessons learned from Blue Zones, lifestyle medicine pillars and beyond. American Journal of Lifestyle Medicine. https://doi.org/10.1177/15598276221118494 Suzuki, M., Willcox, B. J., & Willcox, D. C. (2001). Implications from and for food cultures for cardiovascular disease: Longevity. Asia Pacific Journal of Clinical Nutrition, 10(2), 165–171. https://doi.org/10.1111/j.1440-6047.2001.00219.x The power of environment: A comprehensive review of the exposome's role in healthy aging. (2025). PubMed Central (PMC11858149). https://pmc.ncbi.nlm.nih.gov/articles/PMC11858149/ Social Capital & Community Decline Oldenburg, R. (1999). The great good place: Cafés, coffee shops, bookstores, bars, hair salons, and other hangouts at the heart of a community. Marlowe & Company. https://books.google.com/books?id=cK80BwAAQBAJ Putnam, R. D. (2000). Bowling alone: The collapse and revival of American community. Simon & Schuster. https://www.simonandschuster.com/books/Bowling-Alone/Robert-D-Putnam/9780743203043 Sbarra, D. A., Briskin, J. L., & Slatcher, R. B. (2019). Smartphones and close relationships: The case for an evolutionary mismatch. Perspectives on Psychological Science, 14(4), 596–618. https://doi.org/10.1177/1745691619826535 Twenge, J. M., Joiner, T. E., Rogers, M. L., & Martin, G. J. (2018). Increases in depressive symptoms, suicide-related outcomes, and suicide rates among U.S. adolescents after 2010 and links to increased new media screen time. Journal of Adolescent Health, 62(1), 78–85. https://doi.org/10.1016/j.jadohealth.2017.06.014 U.S. Bureau of Labor Statistics. (2020). American time use survey. U.S. Department of Labor. https://www.bls.gov/tus/ Pennebaker & Authentic Disclosure Brown, B. (2012). Daring greatly: How the courage to be vulnerable transforms the way we live, love, parent, and lead. Gotham Books. https://brenebrown.com/book/daring-greatly/ Pennebaker, J. W. (1997). Writing about emotional experiences as a therapeutic process. Psychological Science, 8(3), 162–166. https://doi.org/10.1111/j.1467-9280.1997.tb00403.x

american health social lessons young deep office writing psychology drawing medicine harvard practical journal human humans labor greece loneliness perspectives chapters rogers smartphones biology implications longevity reclaiming prioritizing bureau increased surgeons replacing darin increases bowling human services daring suzuki okinawa surgeon general schulz american journal perceived blue zones oxytocin labor statistics lifestyle medicine lieberman cognitive science pbs newshour psychological science clinical nutrition sardinia simon schuster baumgartner joiner dan buettner adolescent health heinrichs real community robert putnam pennebaker willcox kirschbaum darin olien bowling alone neuroendocrine waldinger twenge cacioppo ehlert superlife biological psychiatry norton company plos medicine hawkley

V Česku se dá koupit všechno, ale špičková zdravotní péče ne. Proto zdravotnictví vždycky bylo a stále je tak cennou politickou kořistí, říká kardiolog a spisovatel Josef Veselka (296)

Procento Miloše Čermáka

Play Episode Listen Later Jun 11, 2026 98:27

Posloucháte Jedno procento Miloše Čermáka. Já jsem Miloš Čermák a moje jedno procento jsou dva centimetry na výšku a asi kilogram živé váhy. Jedno procento je taky podcast, kam si zvu zajímavé a zábavné hosty. Nebo prostě lidi, které mám rád či z různých důvodů obdivuju.Josef Veselka za poslední tři roky nikomu nezachránil život. Což je něco, co je v jeho životě zcela nezvyklé: předtím zachraňoval životy na denní bázi. Ne proto, že je superman nebo má mimořádné schopnosti. Ale protože je kardiolog. Zachraňování životů je něco, co kardiologové dělají běžně. Je to jejich práce. Josef Veselka tuhle práci miloval, a teď ji už tři roky nedělá, a nikoli proto, že si to tak vybral.Disclaimer: Josef Veselka je můj kamarád a známe se dlouho, a myslím i dobře. Nejsem nezaujatý novinář ani komentátor. Tohle je ostatně už pátý podcast za sedm let, který jsme spolu natočili. Ne proto, že bych mu chtěl dělat reklamu nebo propagaci, ani jedno nepotřebuje a nestojí o to. Ale protože se nám spolu dobře povídá.A taky proto, že Josef Veselka má vždycky co říct. Pořád je totiž vědec, a to ne ledajaký: před měsícem mu vyšla studie v The American Journal of Cardiology, a on je jejím prvním autorem. Týká se léku, který může změnit léčbu hypertrofické kardiomyopatie, tedy nemoci, v níž Veselka patří ke světové špičce.Zároveň je spisovatel. Právě vydal thriller Prezidentské konzilium, první díl tetralogie Správci systému. Je o tom, co se stane, když se kolem nemocného prezidenta sejdou chytré hlavy a každá sleduje jiné cíle, než se zdá. Veselka ví, o čem píše: v jednom prezidentském konzíliu, tom Havlově, sám seděl. Ale pozor, prezident v románu není Havlem inspirovaný. Skoro by se dalo říct, že je charakterově na úplně druhém konci spektra. A vzorem pro Veselkovu postavu nebyl žádný z prezidentů, které Česko mělo. Je to postava komplexní, šokující... a víc neřeknu, protože už bych prozrazoval děj. Veselkova rada budoucím prezidentům mimochodem zní: nechtějte konzilium, chtějte jednoho fachmana.Mluvili jsme o tom, proč Josef Veselka ydržel v německé nemocnici jen čtyři měsíce, přestože tvrdil, že chce pracovat až do smrti. Proč? Třeba proto, že mu tam stokrát řekli, že je překvalifikovaný. Německé zdravotnictví popisuje jako excelovou tabulku, kde má každý své místo — a on byl to číslo v tabulce, které bliká červeně. Povídali jsme si i o tom, co cítil, když policie zatkla ředitele Motola, s nímž si patnáct let tykal, ale který smybolizoval nespravedlnost toho, že po několika dekádách v oboru odešel ze sálu, kde sám sebe vnímal jako nejvíc užitečného. Co tedy cítil? Byly to tři různé emoce a mezi nimi jen dny. Jaké emoce to byly? Poslouchejte.A konečně, mluvili jsme i o tom, proč se v Česku dá koupit lecos, ale špičková zdravotní péče ne, a proč je proto zdravotnictví tak cenná kořist pro politiky. Cennější než například České dráhy.Samozřejmě došlo na umělou inteligenci. Veselka napsal o své nemoci tři knihy a stovku odborných článků, a přesto říká, že v testu z vlastního oboru by ho ChatGPT porazil. Svému chatu říká Maxi a konzultuje s ním i vlastní zdraví. Pokud chcete v AI najít partnera, který vám bude pomáhat, a nikoli bojovat s vašimi lékaři, i to se v dnešní epizodě dozvíte.Připomínám: v pátek 19. června mám v Divadle v Řeznické první reprízu svého standupového speciálu. Hodně mi na tomhle materiálu záleží, nejen proto, že se ke standupu vracím zhruba p roční pauze, a je to osm let od mého posledního sólového speciálu. Ten se jmenoval Manželka mi slíbila černošku, a i o tom bude v Řeznické řeč.Těším se na vás, a lístky si můžete koupit na webu divadla. Odkaz najdete na mém webu Jedno procento. Ještě jednou díky. A teď už …… přeju příjemný a pohodový poslech.

ai man pr chatgpt ale pov jak spr josef sv cardiology american journal proto nebo jedno pokud skoro bylo hodn tohle zdravotn samoz byly odkaz zachra nejsem prezidentsk poslouchejte spisovatel mluvili cenn poslouch veselka havlem

Islam in English

New Books Network

Play Episode Listen Later Jun 10, 2026 36:41

In this episode of the Language on the Move Podcast, Tazin Abdullah speaks with Dr. Oludamini Oguannaike, Associate Professor of African Religious Thought and Democracy at the University of Virginia. Tazin and Oludamini talk about his work into how languages, such as English, express concepts that originate from onto-epistemic perspectives that are not historically associated with the English language. They discuss his 2019 article “Islam in English,” which he co-authored with Dr. Mohammed Rustom and how this research is expressed in the literary genre in his book of poetry called The Book of Clouds. The conversation considers how the distinctive philosophical and metaphysical concepts associated with Islam collide with the use of English as a result of the global dominance of English. Tazin and Oludamini discuss how he has used his research and knowledge of historical religious thought to express these concepts using English in poetry. References Ogunnaike, O. (2024). The Book of Clouds. Fons Vitae of Kentucky. Ogunnaike, O., & Rustom, M. (2019). Islam in English. American Journal of Islamic Social Sciences, 36(2), 102-111. For additional resources, show notes, and transcripts, go here. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

university english language kentucky islam associate professor democracy clouds american journal move podcast rustom mohammed rustom

Michael Shermer speaks with Oxford philosopher Carissa Véliz about the long human desire to know the future—from ancient oracles and astrology to AI, surveillance capitalism, predictive policing, and "data-driven" decision-making. Véliz argues that prediction is rarely neutral: the same machinery that collects personal data also tries to forecast behavior, and once institutions start treating predictions as facts, forecasts can become tools of control. The conversation gets into why privacy matters for democracy, how algorithms can turn human lives into self-fulfilling prophecies, and why extraordinary people often fall outside predictive models. Shermer and Véliz also discuss the limits of science, the replication crisis, crime statistics, effective altruism, utilitarian ethics, and free will. Carissa Véliz is an associate professor at the Institute for Ethics in AI at the University of Oxford. Her first book, Privacy Is Power (Melville House) was an Economist book of the year and has been published in seven languages. Her academic work has been published in The Harvard Business Review, Nature, AI & Society, and The American Journal of Bioethics, among others. Her new book is Prophecy: Prediction, Power, and the Fight for the Future, from Ancient Oracles to AI.

When One Plus One Equals Three: A Conversation with National Aphasia Synergy

Aphasia Access Conversations

Play Episode Listen Later Jun 9, 2026 48:14

Episode 138 When One Plus One Equals Three: A Conversation with National Aphasia Synergy In this episode you will discover: 1. People with aphasia hold the map. At NAS, people with aphasia don't just have a seat at the table — they built the table. Real peer leadership changes everything about how an organization thinks and acts. 2. Recovery is about more than speech. The isolation and psychological distress that follow aphasia are just as real as the communication challenges — and just as deserving of attention and support. 3. Peer-befriending is life participation in action. When people with aphasia support one another through shared experience, that's not a supplement to good care — it is good care. 4. Sinergia: one plus one equals three. When survivors and professionals work as true equals, something greater emerges than either could create alone. June is National Aphasia Awareness Month, and around here, that means it's time for one of my favorite podcast traditions. For the past few years running, we've spent this month in conversation with people who know aphasia from the inside — those living it every day. Today is no exception, and this one is a conversation I've genuinely been looking forward to. Welcome to the Aphasia Access Conversations Podcast. I'm Katie Strong from Central Michigan University, where I lead the Strong Story Lab, and I'm a member of the Aphasia Access Podcast Working Group. Aphasia Access is dedicated to transforming services and environments so people with aphasia can participate more fully in life — and today's guests are living proof of exactly what that looks like. Today I'm speaking with two leaders from National Aphasia Synergy — known as NAS — a peer-led nonprofit founded in 2021 by people with aphasia, for people with aphasia. NAS was built on the belief that those living with aphasia are best positioned to support others on the same journey. Through peer-befriending, technology empowerment, and community building, NAS works to end the isolation that so often follows a stroke — connecting people across the country through a shared sense of what they call Sinergia: the idea that when survivors and professionals work as true equals, one plus one equals three. Today's conversation feels especially meaningful to me. I've had the privilege of seeing Trish and Amy in action at conferences like Aphasia Access and ASHA — learning from their presentations and watching their advocacy make ripples far beyond those conference walls. As someone who researches friendship and aphasia, I've followed the peer befriending movement closely — it began in the UK, and when I heard that NAS was bringing it to the United States, led by a peer organization, I thought: this is what life participation actually looks like. Before we get into the conversation, let me tell you a bit more about our guests. Trish Hambridge is the President and Founder of National Aphasia Synergy. Trish has lived with aphasia since her stroke in 2008, and that experience is the foundation of everything she has built. A former project manager for AppleCare, Trish has become not only a powerful advocate but a published researcher — partnering with research teams to influence the questions being asked and the evidence being built in our field. Her co-authored work spans game-based rehabilitation design, posttraumatic growth in aphasia, and the measurement of motivation and psychological needs in aphasia rehabilitation — all published in leading journals including the American Journal of Speech-Language Pathology. She has spoken at conferences including the Aphasia Access Leadership Summit, Aphasia Access Chautauqua and ASHA, serves on the Disability Advisory Committee in Dunedin, Florida, and is a member of Voices of Hope for Aphasia. Her vision brought NAS to life, and her leadership — in the clinic, in the research literature, and in the community — continues to shape it. Amy Walters is the Vice President of National Aphasia Synergy. Amy has lived with aphasia since her stroke in 2018 — a stroke that, in a striking twist of fate, occurred while she was attending a neurosurgical conference. A Harvard graduate with a Master of Public Health from Johns Hopkins, Amy spent 30 years as a senior leader in the medical device industry before her stroke, and she has channeled that same expertise and drive into aphasia advocacy. She has presented at neurosurgical conferences to raise awareness, participates in aphasia groups across the country, and brings a remarkable combination of professional knowledge and lived experience to everything NAS does. So — let's get into the conversation. Katie Strong: Trish and Amy, welcome. I'm so excited to have you both here today and learn about what's going on in National Aphasia Synergy. Trish Hambridge: Thank you for the chance to meet. Amy Walters: We are so pleased to be here with the Aphasia Access Community. Katie Strong: Well, we're delighted that you are sharing your time and expertise with us. I wanted to get started by asking about National Aphasia Synergy. How was it created? Just wondering if you could share the origin story of the organization and how that concept of synergy or working together defines your mission. Trish Hambridge: Long time ago, I had a stroke, major stroke. But I was the same person then as I am now. I remember sitting on the hospital patio in San Jose and Karen, my good friend from college and speech therapist was there, and she was teaching everyone about aphasia. My friends and family were so patient. I remember my Dad talking to me and say, "You are stubborn." and I said, "Thank you!" Because that choice – being subborn - changed everything and gave me the chance to get my identity back. Katie Strong: So, Trish, just to verify, you're saying your stubbornness got you where you are right now. Trish Hambridge: Yes, but yes! Katie Strong: Love it. Trish Hambridge: Sorry to say, I have issues! But going back to the beginning, I had only had five words. Even my 'yes' and 'no' were flipped. Traditional homework is not my cup of tea. Shhh! Quiet, I'm lazy! I needed a better strategy, and I found it with P2Go. It's so much more than an app. It is the tool that gave me my voice back. Katie Strong: I love that, so if I'm understanding correctly, traditional homework is not for you, and that you really needed something that was technology based, which goes back to your expertise in your life, career to be able to really help you communicate, and it was the P2Go. Trish Hambridge: Yeah, yeah, is small, is so, is easy, my opinion. Katie Strong: Well, that's what we're here for today, is your opinion. Trish Hambridge: In 2016, a move to Dunedin, Florida changed everything. I joined Voices of Hope and finally found my community. Then the pandemic hit. But it couldn't stop our connection. We moved to Zoom. I want to be honest, though: some of my friends didn't make it through that storm. Their pain is part of this journey. We build this community in their honor. Katie Strong: Oh, that's really touching, you know. It is. It's hard, so many friends don't stay in our lives for many reasons, but aphasia can really be a challenge for friends sticking around. Trish Hambridge: Yeah, and the technology is not my cup of tea. Katie Strong: Wonderful, wonderful. Thank you for sharing that. Trish Hambridge: In 2021, I stepped up. I moved from a 'Lead Pathfinder' to the Founder of National Aphasia Synergy. I reached out to Debbie Yones, the big cheese of Voices of Hope. She and the Board Director gave me wise advice to help me grow. I didn't do it alone. My sister and my sister-in-law helped me think through the logistics. They helped me build the support for the nonprofit. Because of them, my vision became a reality. Katie Strong: So, your consultation with those important people to your life really helped National Aphasia Synergy become a reality. Trish Hambridge: Yeah. Finally, I asked Amy to join the mission. She became part of the organization. Now, we are moving forward together. Katie Strong: Thanks, Trish. I love that. Amy Walters: Thanks, Trish. Nine years ago, I had my stroke at the neurosurgical conference. Ironic, right? Yeah, the conference was in Colorado Springs. I was in a medically induced coma for 10 days and diagnosed with Global Aphasia. Then I was airlifted to the Shepherd Center in Atlanta, Georgia, where I had a craniotomy and cranioplasty. On the flight I remembered thinking, "Am I in a simulator? What's happening to me?" Katie Strong: Wow! That sounds surreal! Amy Walters: My career was in clinical affairs for a medical neurosurgical device company, so I am professionally and personally familiar with neuroplasticity. I know how crucial neuroplasticity is to our physical, mental, and emotional recovery. National Aphasia Synergy was born from a deep need for collaborative survivor-led company. Katie Strong: The advocacy you're doing is really amazing, and I'm so excited for our listeners to be able to hear more about it. Amy Walters: Thank you. When we look at the aphasia community today, we see massive gaps. Most organizations are built for us, but they aren't led by us. The 'medical way' focuses only on the speech deficit, but it leaves a gaping hole in mental health, identity, and social connection. The research is heartbreaking: 40% to 60% of stroke survivors with aphasia experience chronic depression, and in early recovery, a staggering 93% experience high levels of psychological distress. This isn't just about the survivor—46% of our family members also face depression. Our mission is to bridge those gaps. We aren't just here to 'fix' speech; we are here to empower the whole person. We call it Sinergia—the Greek word for Synergy. It means we don't work in silos. We don't have 'experts' on one side and 'patients' on the other. We have a partnership where 1 plus 1 equals 3. Katie Strong: I love it! Amy Walters: We are moving away from the isolated patient model and toward a Sinergia where survivors and professionals work as equals to reclaim our lives. We are here to educate and empower our peers to use technology to reclaim their voices. But more importantly, we are here to promote peer-befriending. We reach out to those who are new to this path or struggling to find their way, because no one should walk this road alone. Katie Strong: I know, Amy, I just am so excited. I've been watching this peer befriending happen over in the UK, or reading about it, and hearing about it, and I was just so delighted when I heard that National Aphasia Synergy was taking this up and helping us to, to have a really solid connection. I think one of the things that breaks my heart the most is when I meet someone who has aphasia, who's been living with aphasia for a really long time, and they've never met anyone else who had aphasia. Amy Walters: Heartbreaking. Katie Strong: It really is. It really is. Amy Walters: Our goal is to develop a national community that encourages optimism. We believe a positive outlook isn't just a 'nice feeling'—it is a strategy for recovery. Katie Strong: Heck, yes! Amy Walters: At NAS, we don't just look for what's lost; we build on the strengths that remain. There were gaps in the Aphasia Community. Trish Hambridge: Speech Therapists and care partners are vital to recovery. They have good intentions, but the 'medical way' is often the wrong way. Katie Strong: Yeah, yeah, it's not quite the right way. Trish Hambridge: Many researchers only survey the Speech Therapists and the partners. But what about me? What about us? What am I, chopped liver? Think about the last time someone completely iced us out. It hurts, right? It honestly chips away at our sense of self, leaving us clueless as to where we actually fit in. Katie Strong: Yeah, so Trish, just to recap this for the listeners, you're saying when somebody ices you out, you're asking the listeners to reflect on how that really feels, Trish Hambridge: Yeah, I email [a researcher], and have offered [to be a part of their team] but they are like "Oh no, but sorry." Katie Strong: I hear, I hear you. Yeah and I think what you're bringing up - and you and Amy are bringing up such a great point that as the aphasia research community has not always included people with aphasia. Or they're only including people with mild aphasia versus more severe types of aphasia, so I love that you're calling this out and shining light on it. It's, it's time. Trish Hambridge Here's what the research tells us. Therapists and partners see the journey from the outside. But those of us living it? We know the honest truth. Katie Strong: Yeah, yeah, so as the clinicians, the therapists, and the care partners see that journey from the outside, and you all are living it for sure. Trish Hambridge: It is the 'Chicken and the Egg' problem: Does the partner change first? Or does the people with aphasia change? The answer is: The Environment. We must change the environment to find true recovery. We need to move from being 'patients' to being Lead Pathfinders. Katie Strong: Yes, so I love it. You're, you're flipping the script there and reclaiming your identity, or renegotiating it from that patient role to being a lead pathfinder. I love that terminology. Thank you. Thank you. One of you said this earlier that organizations are for people with aphasia, but National Aphasia Synergy is led by people with aphasia. Why is this distinction critical for the community to understand, and how does it change the way an organization is run? Amy Walters: Right, Katie. In the past, organizations were built for us, like a charity. But National Aphasia Synergy is different. We are led by people with aphasia. We are moving from 'being helped' to leading. This is more than an organization. It is a revolution of identity. At National Aphasia Synergy, we are flipping the script on leadership. Our Board makes decisions with one clear priority: putting voices with aphasia at the forefront. That means leaders like Trish, Bruce, and me are the ones making the big calls. We collaborate with wonderful professionals, like Kait, our SLP, Helen, our Financial and Secretarial support and Will Evans, our Volunteer Consultant. They are essential to our success. They ensure our communication is accessible and our business stays strong. I always think of our board meetings being like a United Nations meeting with "international representatives" (i.e., China, France, Japan, etc.) each of us is coming to the table with a different lived experience, different aphasia types, etc. We work together to "translate" and work through our differing communication styles. But make no mistake: The people with aphasia are the primary drivers of the vision. The professionals provide the tools, but we hold the maps. Katie Strong: Such a great analogy. I love it and it also sounds like your work is fun too. Amy Walters: Driving you crazy, but you mean you mean you mean, yeah. Hold the phone! Katie Strong: Oh, that's great. I love it. Well, what does National Aphasia Synergy offer that others should know about? Trish Hambridge: Look at what we have built together: First, our Peer Befriending Program. A team of four SLPs and four people with aphasia worked as equals to create our training. Today, we have 15 volunteer Allies trained and ready to support the community. Katie Strong: I love it. So, 15 people with aphasia, volunteer Allies, have been trained as peer befrienders to go out and connect with other people who newly have aphasia. Trish Hambridge: Right, but anything like… Katie Strong: Or rather, anybody who has aphasia that they're wanting to connect with. Trish Hambridge: Come! Come! But we meet on Zoom. Katie Strong: On Zoom, right? Yeah, absolutely. This is all virtual, which is amazing, you know, because you get a good reach, a really, a really great reach. What else is going on? Amy Walters: Second, our Aphasia & Mental Health Video. We have four excellent SLPs sharing the research, stats, resources and the power of neuroplasticity. And we also surveyed 10 people with aphasia to capture the honest truth of our emotional journeys and provide 10 essential tips for recovery. Trish Hambridge: I always start with a roadmap. But originally, we were filming something completely different. But three weeks before the shoot, I went to Debbie and asked: 'What do you think?' She said, 'There are enough basic videos out there... why doesn't NAS focus on Mental Health?' Katie Strong: Yeah, okay. So, you were doing all this planning, and then three weeks before the shoot, you went and talked to Debbie and said, "What do you think?" And she said, "There's already enough videos out there on basic aphasia, but not on mental health. I love it! Trish Hambridge: Yeah and so I agree!!! We agreed right away. We made a right turn... And changed the plan on the fly! I ran a preview for my friends at Voices of Hope. They loved it, but they asked the killer question: 'Where is the actual resource? Where do we go for help?' Katie Strong: Trish, you are speaking to my heart here, and I know I'm one of those "outsider perspectives" as a clinician. But we just don't have great resources for mental health. It's really challenging. So, I love that your friends at Voices of Hope called you out on that. What happened after that? Amy Walters: That was the lightbulb moment, right? Trish Hambridge: Yeah, a video wasn't enough—we needed a map. So, we built the Aphasia and Mental Health Resources paper. The researchers and I had some serious back-and-forth debate, but that's how you get a solid plan. We ended up with something really cool: real tools for real people. Katie Strong: Love, love it! Trish Hambridge: Third, our Adaptive Growth Culture paper. This provides a brand-new map for recovery that the whole world can use to look past the 'broken parts.' Katie Strong: Yeah, Trish, I've heard you speak on this. That talk you gave it, ASHA. I'm going to say listeners, particularly clinicians, you should check this out, because we need to get our clients with aphasia, our lead pathfinders with aphasia to be able to think in this sort of way, so yeah, Trish Hambridge: But like I have like the speech therapist and the caregiver, and people with aphasia - it like, look right -- is the good plan. Katie Strong: Love it, fantastic, Amy Walters: Kait and I shared five powerful aphasia stories on video to show our diversity, our strength, our inhumanity, frankly. All of this lives on our National Synergy website. These aren't just projects, they are the proof that when people with aphasia lead, we create world that actually works for us. Katie Strong: Oh, this is fantastic. And we'll have links to your website in the show notes, but you can certainly Google National Aphasia Synergy, and the website pops right up. I've been exploring it for a little bit, but I was looking at it again this morning, and there's just such great, great stuff on there. So please go and check it out. Well, I'm curious, Amy and Trish, what's on the horizon for National Aphasia Synergy, and how can our listeners, whether they're Aphasia Access members or people living with aphasia get involved or support your work. Amy Walters: We are so proud of what we have built, but we are just getting started. This is our Call to Action. Trish Hambridge: We want the world to get excited about Mental Health! Katie Strong: And I think get excited about your Adaptive Growth Culture too. Trish Hambridge: Yeah! We recently presented a poster at the Chautauqua virtual conference, and the feedback from Aphasia Access members was powerful. The keynote speaker, Dr. Nina Simmons-Mackie, spoke about moving from 'managing a condition' to 'owning a life.' That is exactly what we do! We focus on the strengths, the emotions, and the identity that the old medical model ignores. Katie Strong: Yeah, so okay. So, Trish, you, you were, I think you presented you National Aphasia Synergy presented a poster at the Chautauqua, the Aphasia Access Chautauqua recently. Trish Hambridge: First time presenting a poster! Katie Strong: I love it, I love it. Yep, and the feedback that you got from the Chautauqua attendees was spectacular, right? And that's when, and, and, and Dr. Simmons-Mackie or Nina Simmons Mackey took that idea and we wove it into her keynote at the end, right, and talked about how it's important for us to support people and people with aphasia and care partners move from managing a condition to owning a life. I mean, that that's powerful stuff. I love it! Trish Hambridge: I'm so honored. Katie Strong: Well, you are out there making an impact. Amy Walters: Thank you. We are building something historic, and we want you to be part of it. Here is how you can join the revolution: Trish Hambridge: To the speech therapists and researchers, Help us build our evidence base. We want the test that adapted growth culture map to prove how it improves mental health and builds confidence. Don't just watch from the sidelines—come test this with us! Soon, I'm taking the Adaptive Growth Culture to the global stage. I'll be at the International Aphasia Rehabilitation Conference in Athens. Katie Strong: You'll be at the International Aphasia Rehabilitation Conference, or IARC, in… Trish Hambridge: Athens!! I am presenting our Adaptive Growth Culture Poster to the top minds in the field. Katie Strong: Fantastic. Trish Hambridge: We have built the roadmap. Now, the researchers will provide the data-driven proof. It is time to see the Adaptive Growth Culture in action. We are moving from lived experience to clinical evidence. Katie Strong: I love it, moving from lived experience to clinical evidence. Amy Walters: That's right, that's right, Trish. If you run a community group, a local program, or a support network, we want to connect with you. Help us build this referral network so that no one is left behind in isolation. We aren't just looking for 'places to go' to pass the time. We are looking for places where we can belong and grow. We are looking for communities that see our potential, not just our deficits. To my peers with Aphasia: Your voice is our power. Share your story or send us a shout-out with your favorite tips and tricks. We also need Buddies for our Peer Befriending program. Help us show the world that we are truly 'owning our lives.' To the Volunteers: We are looking for passionate people to join our Board of Directors. We specifically need one more person with aphasia, as well as SLPs, care partners, and friends. The only requirement? You must believe in the Adaptive Growth Culture. Whether you have the tools or you hold the map, there is a seat at the table for you. Visit us and let's grow together! Katie Strong: Amazing. I hope that our listeners will take you up on the offers that you just laid out there, and that they'll also go out there and share with others that they need to hook everybody up with National Aphasia Synergy. It's a great organization. I enjoyed learning about it more today. And Amy and Trish, I so appreciate you both being here with us and sharing your stories and the amazing work that's going on in National Aphasia Synergy. Trish Hambridge: Thank you. Aphasia Access is fantastic! Katie Strong: I'm glad that you're enjoying Aphasia Access, too. It's a great network, and it's great that we're having lots of communities continue to grow and blossom to support people living successfully with aphasia. Amy Walters: Hear, Hear! Katie Strong: Thanks. You too. Amy Walters: Thank you. Katie Strong: Have fun in Greece. Trish Hambridge: Yay! Amy Walters: Jealous! Katie Strong: Me too, me too. Amy Walters: Bye, bye. Trish Hambridge: See you. Bye. On behalf of Aphasia Access, thank you for listening. For references and resources mentioned in today's show, please see our show notes, available on our website at www.aphasiaaccess.org. There you can also become a member of our organization, browse our growing library of materials, and find out about the Aphasia Access Academy. If you have an idea for a future podcast episode, email us at info@aphasiaaccess.org. For Aphasia Access Conversations, here at Central Michigan University in the Strong Story Lab, I'm Katie Strong. Resources Below is a list of links to the National Aphasia Synergy (NAS) resources and other organizations as discussed: NAS Website: https://nationalaphasiasynergy.org NAS email: info@nationalaphasiasynergy.org NAS Facebook page: https://www.facebook.com/WeRSynergy (to keep up with what's going on at NAS and for inspirational, adaptive growth mindset content) NAS YouTube Channel: https://www.youtube.com/@nationalaphasiasynergy1410 (to watch our Aphasia Stories series, learn about resources, and tune into our quarterly video newsletter, "The Synergy Turf" to hear real people with aphasia) NAS Adaptive Growth Culture paper: https://drive.google.com/file/d/1VIq0juI4FTPKqF0Cev8qZAI5I5po5ouO/view?usp=share_link NAS "You Have Options!" Paper: https://drive.google.com/file/d/1PBgvb1mDrjnFASaK_dpGL2gnZND_CjaU/view?usp=share_link NAS Aphasia & Mental Health video: https://www.youtube.com/watch?v=GThkxrKbQTI NAS Aphasia & Mental Health Resource paper: https://drive.google.com/file/d/1pXbFLtZJ8KZ9Pxpg3HVZHBEd_D7BnsED/view?usp=share_link NAS Aphasia Stories video series: https://youtube.com/playlist?list=PLk1GJP6QGrPDOapMhQlmAUBHfVb5-Mnfi&si=BIuoNmeu-TM-ab65NAS Peer Befriending: To get involved with NAS Peer Befriending, contact info@nationalaphasiasynergy.org o Flyer: https://drive.google.com/file/d/1dCETc1pZck59mw6OgaEjZGnXWOcdSlCh/view?usp=sharing o Video: https://youtu.be/0RNvCeh0BKM Referenced resources and organizations: Proloquo2Go AAC App mentioned (what Trish uses): https://www.assistiveware.com/products/proloquo2go Voices of Hope for Aphasia: https://www.vohaphasia.org/

The Hidden Reason You Feel Exhausted & How to Feel Better Now

The Mel Robbins Podcast

Play Episode Listen Later Jun 8, 2026 58:26

If you've been feeling exhausted, tired, bloated, anxious, in pain, or just not like yourself, you need to hear today's episode. Today, Mel sits down with one of the most respected medical researchers in the world, gastroenterologist Dr. Brennan Spiegel, to uncover the overlooked, invisible force that's having a shocking impact on your energy, strength, gut health, mood, and every single cell in your body – even how fast your body ages. Whether you're dealing with fatigue, back pain, swelling, digestion issues, or a heaviness in your body that you can't shake, Dr. Spiegel says these are all signs you shouldn't ignore. Dr. Spiegel is a gastroenterologist and the director of Health Services Research at Cedars-Sinai Medical Center in Los Angeles, one of the leading medical centers in the United States. He is also a professor of medicine and public health at UCLA. He trained at Cedars-Sinai and UCLA, and is a pioneering researcher in the areas of gut health, the usage of AI in medicine, and tools that help patients with pain, anxiety, and chronic illness. He's the founding editor of the Journal of Medical Extended Reality and he served as Editor-in-Chief of the American Journal of Gastroenterology. Dr. Spiegel has published more than 300 peer-reviewed scientific papers, his research has been cited 30,000 times, and he is the author of Pull: How Gravity Shapes Your Body, Steadies the Mind, and Guides Our Health. What Dr. Spiegel reveals will challenge the way you think about your body and, more importantly, give you a completely new, practical way to start feeling better immediately. And it may give you the words and the insight you've been missing to help your aging parents and other loved ones finally start feeling better, too. By the end of this episode, you'll understand: -Why a “bendy” pinky might be a clue to what's going on in your gut -10 foods that boost serotonin production in your body -The most effective treatment for IBS - and it's probably not what you've tried -A quick way to notice how the force of gravity is showing up in your body -How to make yourself taller in just a few minutes -Why standing on one leg is linked to a longer life -How a weighted vest can change your posture almost immediately -A surprising reason rollercoasters feel unbearable for some people -What “gravity management” looks like in real life -One small habit that can improve how your body handles gravity Dr. Spiegel says the powerful, invisible force shaping every moment of your life is one you can learn to work with – and he'll show you how. This is one of those conversations that will change how you see your body, your health, and what it means to be fully alive. For more resources related to today's episode, click here for the podcast episode page: If you liked the episode, check out this one next: Change Your Body & Your Life in 1 Month: 4 Small Habits That Actually Work. Connect with Mel: Order Mel's new product, Pure Genius Protein Get Mel's newsletter, packed with tools, coaching, and inspiration. Get Mel's #1 bestselling book, The Let Them Theory Watch the episodes on YouTube Follow Mel on Instagram The Mel Robbins Podcast Instagram Mel's TikTok Subscribe to SiriusXM Podcasts+ to listen to new episodes ad-free Disclaimer Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

united states ai los angeles mind hidden journal ucla spiegel exhausted ibs feel better american journal simplecast gastroenterology cedars sinai cedars sinai medical center health services research

Épisode 29 | Cytomégalovirus (CMV): l'essentiel, de la grossesse à bébé

mg par kilo - balado

Play Episode Listen Later Jun 8, 2026 40:03

Avec Dre Isabelle Boucoiran, gynécologue-obstétricienne, Marie-Michèle Poirier, infirmière clinicienne à la clinique d'infectiologie mère-enfant (CIME) Caroline Morin, pharmacienne en obstétrique et à la clinique, et Fatima Kakkar, pédiatre infectiologue, nous allons:définir ce qu'est le cytomégalovirus (CMV) et comprendre les risques de complications pour le bébé si l'infection survient durant la grossesse;discuter de l'infection chez la femme enceinte et des mesures non-pharmacologiques pour réduire le risque de transmission fœtale;expliquer le processus de détection, de diagnostic, d'évaluation et de prise en charge des nouveaux-nés atteints d'une infection congénitale à CMV.Références:Boucoiran, I. L'infection à cytomégalovirus (CMV) durant la grossesse. Naître et grandir. Mars 2026. Barton, M., Forrester M., McDonald J. Mise à jour sur l'infection congénitale à cytomégalovirus : la prévention prénatale, le diagnostic néonatal et la prise en charge (2026). Société canadienne de pédiatrie.Boucoiran, I. et autres. « Guidelines No. 420: Cytomegalovirus Infection in Pregnancy », Journal d'obstétrique et gynécologie du Canada, vol. 43, no 7, juillet 2021. jogc.comCMV Canada: https://cmvcanada.com/fr/Guide de CMV Canada pour les femmes en âge de procréer et les futurs parents: https://cmvcanada.com/wp-content/uploads/2025/07/CMV_Awareness_FR_Web.pdf CMV Québec: https://cmvcanada.com/fr/cmv-quebecs/ CHU Sainte-Justine. CMV: complications de grossesse chez la mère. (2018)Chatzakis C, Ville Y, Makrydimas G, Dinas K, Zavlanos A, Sotiriadis A. Timing of primary maternal cytomegalovirus infection and rates of vertical transmission and fetal consequences. American Journal of Obstetrics and Gynecology. 2020;223(6):870-883.e81 Leruez-Ville M, Chatzakis C, Lilleri D, et al. Consensus recommendation for prenatal, neonatal and postnatal management of congenital cytomegalovirus infection from the European congenital infection initiative (ECCI). The Lancet Regional Health - Europe. 2024;40:100892. Les invité(e)s et l'animatrice ne déclarent aucun conflit d'intérêt.Idée originale, réalisation et révision, animation et gestion des réseaux sociaux: Émilie Roy-St-PierreCaptation et montage: Philippe Lacroix (depuis janvier 2024), spécialiste en audiovisuel, et Antoine Palardy, (depuis octobre 2025) technicien en audiovisuelConseillère en communication: Pascale Chatagnier (depuis mai 2025) ; Katrine Louis-Seize (janvier 2024 à mai 2025)Technopédagogue: Carl-Philippe Sauvé (depuis janvier 2026)Logo: Équipe des communications et du graphisme du CHU Sainte-JustineMusique: Samuel RossCollègues, ami(e)s et famille, merci pour votre précieux soutien. © 2024-2026, CHU Sainte-Justine. Tous droits réservés.Merci pour l'écoute! Allez mettre une réaction sur vos épisodes préférés, partagez la bonne nouvelle sur Facebook/Instagram et abonnez-vous pour ne rien manquer

Ep. #996 -

Lo Psiconauta

Play Episode Listen Later Jun 6, 2026 43:04

180: [Amber Rodgers] A Crisis Victim Within the System // Part 2

What Came Next

Play Episode Listen Later Jun 5, 2026 35:01

Content warning: childhood abuse, childhood sexual abuse, sexual assault, rape, abduction, missing persons, gun violence, murder, and mental illness.Amber Rodgers is a survivor, business professional, and creative from Texas. As early as she can remember, her life was filled with chaos. By the time she was fourteen, she was a multi-crime survivor, and by 19 she would serve as a witness in her best friend's murder trial. Amber moved forward by cultivating a successful career and loving family, until her past trauma instigated a cascading effect in her mental health and relationships. Although Amber has shared portions of her story at-large, it took her decades and a life-altering mental health journey to realize the deep impact her teen years had had on her. The Broken Cycle Media team is deeply appreciative of Amber's transparency, rawness, and advocacy. These episodes are dedicated in loving memory of Kytrina Marie Locascio.Sources: -Centers for Disease Control and Prevention. “About Adverse Childhood Experiences.” CDC, U.S. Department of Health and Human Services, 2025, https://www.cdc.gov/violenceprevention/aces/. -Centers for Disease Control and Prevention. “Adverse Childhood Experiences (ACEs).” CDC Vital Signs, U.S. Department of Health and Human Services, https://www.cdc.gov/vitalsigns/aces/index.html. -Centers for Disease Control and Prevention. “Psychosocial Factors and Health Equity.” CDC, U.S. Department of Health and Human Services, https://www.cdc.gov/dhdsp/health_equity/psychosocial.htm. -Felitti, Vincent J., et al. “Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults: The Adverse Childhood Experiences (ACE) Study.” American Journal of Preventive Medicine, vol. 14, no. 4, 1998, pp. 245–258.-Hughes, Karen, et al. “The Effect of Multiple Adverse Childhood Experiences on Health: A Systematic Review and Meta-Analysis.” The Lancet Public Health, vol. 2, no. 8, 2017, pp. e356–e366. doi:10.1016/S2468-2667(17)30118-4.-McKay, Matthew T., Laura Kilmartin, Aisling Meagher, Mary Cannon, Colm Healy, and Mary C. Clarke. “A Revised and Extended Systematic Review and Meta-Analysis of the Relationship between Childhood Adversity and Adult Psychiatric Disorder.” Journal of Psychiatric Research, vol. 156, 2022, pp. 159–174. PubMed, https://pubmed.ncbi.nlm.nih.gov/36274532/. -Swedo, Elizabeth A., et al. “Prevalence of Adverse Childhood Experiences Among U.S. Adults—Behavioral Risk Factor Surveillance System, 2011–2020.” Morbidity and Mortality Weekly Report, vol. 72, no. 26, 2023, pp. 707–715, https://www.cdc.gov/mmwr/volumes/72/wr/mm7226a2.htm. -Zhang, Y., et al. “Cumulative Adverse Childhood Experiences and Risk of Mental Disorders: A Systematic Review and Meta-Analysis.” Acta Psychiatrica Scandinavica, 2026, https://www.sciencedirect.com/science/article/pii/S0001691826007559. Accessed 2 June 2026.For additional resources and a list of non-profit organizations that can help, please visit http://www.somethingwaswrong.com/resources*Thank you again to Rula and Quince for sponsoring this episode. *Remember, Rula patients typically pay $15 per session when using insurance. Connect with quality therapists and mental health experts who specialize in you at https://www.rula.com/wcn #rulapod *And don't forget to elevate your summer wardrobe, go to quince.com/wcn for free shipping on your order and 365-day returns, now available in Canada too.

relationships death texas canada health crisis system risk journal prevention cdc victim hughes centers rodgers disease control human services zhang mckay revised american journal health equity prevalence quince meta analysis pubmed preventive medicine childhood abuse leading causes adverse childhood experiences aces morbidity rula childhood adversity vincent j psychiatric research lancet public health cdc vital signs

Ep. 602 “The Gallbladder-Hormone Connection” – How Perimenopause Changes Bile Flow and Gallbladder Health | Menopause, Perimenopause, Gallbladder Health

Everyday Wellness

Play Episode Listen Later Jun 4, 2026 33:43

Welcome to this week's Midlife Minute. Today, I'm focusing on all the questions I received about gallbladder health, including HRT-provoking symptoms, supplements that improve gallbladder health, and evidence-based food interventions. IN THIS EPISODE, YOU WILL LEARN: Why the risk of gallstones and gallbladder inflammation increases during the menopause transition How estrogen and progesterone HRT have different effects on gallbladder functioning The differences in risk between transdermal and oral HRT How the progesterone in HRT can cause gallbladder issues in some women What TUDCA is, and how it supports gallbladder health The value of TUDCA for women who have had their gallbladders removed How various nutrients and supplements support bile flow and gallbladder health What can contribute to gallstone formation Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Gallbladder Research: Cabrera D, Arab JP, Arrese M. UDCA, NorUDCA, and TUDCA in liver diseases: a review of their mechanisms of action and clinical applications. Seminars in Liver Disease. 2019;39(4):397–404. doi:10.1055/s-0039-1696799 Vang S, Longley K, Steer CJ, Low WC. The unexpected uses of urso- and tauroursodeoxycholic acid in the treatment of non-liver diseases. Global Advances in Health and Medicine. 2014;3(3):58–69. doi:10.7453/gahmj.2014.017 Bai M, Yang L, Liao H, et al. Tauroursodeoxycholic acid improves nonalcoholic fatty liver disease by regulating gut microbiota and bile acid metabolism. Journal of Agricultural and Food Chemistry. 2024;72(41):22655–22668. doi:10.1021/acs.jafc.4c04630 Simon JA, Hudes ES. Relation of serum ascorbic acid to serum vitamin B12, serum ferritin, and kidney stones in US adults. *Archives of Internal Medicine.*1999;159(6):619–624. doi:10.1001/archinte.159.6.619 Walcher T, Haenle MM, Kron M, et al. Vitamin C supplement use may protect against gallstones: an observational study on a randomly selected population. BMC Gastroenterology. 2009;9:74. doi:10.1186/1471-230X-9-74 Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL. Long-term intake of dietary fiber and decreased risk of cholecystectomy in women. American Journal of Gastroenterology. 2004;99(7):1364–1370. doi:10.1111/j.1572-0241.2004.30281.x Leitzmann MF, Stampfer MJ, Willett WC, Spiegelman D, Colditz GA, Giovannucci EL. Coffee intake is associated with lower risk of symptomatic gallstone disease in women. Gastroenterology. 2002;123(6):1823–1830. doi:10.1053/gast.2002.37085 Moerman CJ, Smeets FW, Kromhout D. Dietary risk factors for clinically diagnosed gallstones in middle-aged men — a 25-year follow-up study. Annals of Epidemiology. 1994;4(3):248–254. doi:10.1016/1047-2797(94)90099-x Association between dietary magnesium intake and gallstones: the mediating role of atherogenic index of plasma. Lipids in Health and Disease. 2024;23(1):82. doi:10.1186/s12944-024-02074-4 Pitt HA, Doty JE, Murphy MM, Schwarz MB. Progesterone alters biliary flow dynamics. Annals of Surgery. 1999;229(2):205–209. doi:10.1097/00000658-199902000-00008

Tradwives x Eugenics

Material Girls

Play Episode Listen Later Jun 2, 2026 61:17

Dust off your aprons and heat up your cast iron because it's finally time for one of our most requested episodes yet! In this episode, Hannah and Marcelle dig deep into the tradwife phenomenon. Using the viral tradwife influencer Ballerina Farm as a case study, Hannah leads us through a discussion about eugenics, replacement theory, and clean living movements. They also get into influencer culture, the performance of farm life, and…milk. Whew! That's a lot, and it's ALL relevant.This episode is for those of you who love to hate tradwives, are curious about their meteoric rise in popularity over the last few years, or have never even heard of them!Related listening:9 to 5 x Labour Feminism with Zena SharmanGet Out x Horrifying WhitenessWitch, Please: Book 7, Ep. 6 | EugenicsWorks Cited:Agnew, Megan. “Meet the queen of the ‘trad wives' (and her eight children.” The Times 20 July 2024: https://archive.ph/YHB08. “Clean living movement.” Wikipedia. https://en.wikipedia.org/wiki/Clean_living_movement. Accessed 14 May 2026. Elster, N., Parsi, K., & Caplan, A. Guest editorial. “Laundering Public Health: Using Autism to Revive Eugenics.” The American Journal of Bioethics (2026): 1–3. https://doi.org/10.1080/15265161.2026.2659519. “Eugenics and Scientific Racism.” National Human Genome Research Institute 18 May 2022. https://www.genome.gov/about-genomics/fact-sheets/Eugenics-and-Scientific-Racism. Accessed 14 May 2026. Luse, Brittany. “Mormon Moms: Unpacking a national obsession.” It's Been A Minute (NPR) 12 November 2024: https://www.npr.org/transcripts/1212541651. Moskin, Julia. “Tycoon or Tradwife? The Woman Behind Ballerina Farm Makes Her Own Path.” The New York Times 3 December 2024: https://archive.ph/Q9j2J#selection-489.0-489.70. Petersen, Anne Helen. “The Edenic Allure of Ballerina Farm.” Culture Study 10 February 2022: https://annehelen.substack.com/p/the-edenic-allure-of-ballerinafarm. Sykes, Sophia and Dr Veronica Hopner. “Tradwives: The Housewives Commodifying Right-Wing Ideology.” Global Network on Extremism & Technology 7 July 2023: https://gnet-research.org/2023/07/07/tradwives-the-housewives-commodifying-right-wing-ideology/. Valverde, Mariana. The Age of Light, Soap, and Water: Moral Reform in English Canada, 1885-1925. Toronto: McClelland & Stewart, 1991.***To learn more about Material Girls, head to our Instagram at instagram.com/ohwitchplease! Or check out our website ohwitchplease.ca. We'll be back next week with a Material Concerns episode, but until then, go check out all the other content we have on our Patreon at Patreon.com/ohwitchplease! Patreon is how we produce the show and pay our team!Material Girls is a show that makes sense of the zeitgeist through materialist critique* and critical theory! Each episode looks at a unique object of study (something popular now or from back in the day) and over the course of three distinct segments, Hannah and Marcelle apply their academic expertise to the topic at hand.*Materialist Critique is, at its simplest possible level, a form of cultural critique – that is, scholarly engagement with a cultural text of some kind – that is interested in modes of production, moments of reception, and the historical and ideological contexts for both.Music Credits:“Shopping Mall”: by Jay Arner and Jessica Delisle ©2020Used by permission. All rights reserved. As recorded by Auto Syndicate on the album “Bongo Dance”.Hosted on Acast. See acast.com/privacy for more information. Hosted on Acast. See acast.com/privacy for more information.

technology new york times wikipedia acast dust soap petersen extremism american journal eugenics bioethics sykes valverde tycoon caplan material girl global network tradwives parsi elster ballerina farm culture studies scientific racism english canada jay arner

Making Early CKD Detection Count: Ralph Riello, PharmD, and Nihar Desai, MD

Managed Care Cast

Play Episode Listen Later Jun 2, 2026 36:43

Early detection of chronic kidney disease (CKD) means little if it does not lead to timely treatment, yet a significant gap persists between when CKD is found and when evidence-based therapies are started. That disconnect is the focus of the second episode of Beyond the Silo: Integrated Care Across the CRM Continuum, a podcast series from The American Journal of Managed Care®, in which Ralph Riello, PharmD, BCPS, leads a conversation with Nihar Desai, MD, MPH, on how to shift CKD care from a reactive, late-stage model to one that is proactive, pathway-driven, and equitable. The discussion builds on the first episode's focus on urine albumin-to-creatinine ratio underutilization, stipulating that screening has occurred and asking what must happen next. You can listen to the first episode here: https://www.ajmc.com/link/89943

md mph detection american journal pharmd desai ckd bcps managed care nihar

Tradwives x Eugenics

Material Girls

Play Episode Listen Later Jun 2, 2026 61:17

The Mechanics of Magick: Dark Rooms, Float Tanks, Initiation, and the Brain That Sees Without Light Part 1

Play Episode Listen Later Jun 1, 2026 71:29 Transcription Available

Links For The Occult Rejectshttps://linktr.ee/theoccultrejectsOccult Research Institutehttps://www.occultresearchinstitute.org/Substackhttps://substack.com/@theoccultrejects?r=7auau0&utm_campaign=profile&utm_medium=profile-pageCash Apphttps://cash.app/$theoccultrejectsVenmo@TheOccultRejectsBuy Me A Coffeebuymeacoffee.com/TheOccultRejectsPatreonhttps://www.patreon.com/TheOccultRejectsPart 1: The Road of RhythmPart 1 focuses on the drum as an ancient technology of altered consciousness. The argument is not that every beat causes trance, or that neuroscience has proven spirits. The stronger argument is that rhythm enters the human organism through hearing, motor prediction, breath, movement, attention, emotion, expectation, culture, and social synchrony. The drum becomes powerful when sound, body, group, ritual frame, and meaning converge. These sources support the archaeology, neuroscience, EEG research, shamanic studies, possession studies, Indigenous and culturally specific drum traditions, ritual theory, placebo and meaning-response research, ceremonial magic, and modern witchcraft material used in the episode.Core Academic and Scientific SourcesHuels, Emma R., Hyoungkyu Kim, UnCheol Lee, Tirsa Bel-Bahar, Ana V. Colmenero, Alexandra Nelson, Stefanie Blain-Moraes, George A. Mashour, and Richard E. Harris. “Neural Correlates of the Shamanic State of Consciousness.” Frontiers in Human Neuroscience 15 (2021): 610466. Use for the strongest modern EEG anchor. This study used high-density EEG with shamanic practitioners and controls during rest, shamanic drumming, and classical music listening. It assessed altered-state reports alongside brain measures such as power, connectivity, signal diversity, and criticality. Use carefully: the study does not prove spirits or show that drumming mechanically causes trance in everyone. It supports the more careful claim that trained practitioners entering shamanic states with drumming show measurable brain-state differences.Gordon, Yoel, Golan Karvat, Noa Dagan, and Ayelet N. Landau. “Neural Tracking at Theta Predicts Drumming-Induced Altered States of Consciousness.” Scientific Reports 16, no. 1 (2026): Article 10204. Use for the strongest updated drumming/theta/neural-tracking source. This study tested drumming at theta, delta, and alpha-rate rhythms while recording EEG, and found that stronger rhythmic neural tracking at theta was linked to stronger altered-experience reports. Use carefully: this does not mean theta equals the spirit world or that one frequency opens a portal. The serious point is that altered experience may depend partly on how strongly the nervous system tracks rhythmic stimulation.Aparicio-Terrés, R., et al. “The Neurobiology of Altered States of Consciousness Induced by Drumming and Other Rhythmic Sound Patterns.” Annals of the New York Academy of Sciences, 2025. Use for the newer review literature showing that rhythmic sound is now a serious altered-consciousness research topic. This supports the opening claim that modern academia is examining drumming, rhythmic sound, absorption, relaxation, cognition, and neural activity without reducing the subject to one simple “trance frequency.” The review is especially useful for framing the field as promising but still complex.Neher, Andrew. “Auditory Driving Observed with Scalp Electrodes in Normal Subjects.” Electroencephalography and Clinical Neurophysiology 13 (1961): 449–451. Use for the historical bridge between repetitive sound, EEG, auditory driving, and early scientific interest in rhythmic stimulation.Neher, Andrew. “A Physiological Explanation of Unusual Behavior in Ceremonies Involving Drums.” Human Biology 34, no. 2 (1962): 151–160. Use carefully. This is useful as an early attempt to connect ceremonial drumming and physiology, but it should be balanced with Rouget because the “drum simply causes trance” argument is too mechanical.Maurer, R., V. K. Kumar, L. Woodside, and R. J. Pekala. “Phenomenological Experience in Response to Monotonous Drumming and Hypnotizability.” American Journal of Clinical Hypnosis 40, no. 2 (1997): 130–145. Use for monotonous drumming, subjective altered experience, imagery, absorption, and hypnotizability.Maxfield, Melinda C. “Effects of Rhythmic Drumming on EEG and Subjective Experience.” PhD diss., Institute of Transpersonal Psychology, 1990. Use as older supporting context on drumming, EEG, imagery, body-image changes, and subjective altered experience. Do not make this the main scientific proof; use it as background.Nozaradan, Sylvie, Isabelle Peretz, and André Mouraux. “Tagging the Neuronal Entrainment to Beat and Meter.” The Journal of Neuroscience 31, no. 28 (2011): 10234–10240. Use for EEG evidence that the brain can track beat and meter. This supports the claim that the brain does not merely hear rhythm as background sound; it can represent rhythmic structure in measurable ways.Nozaradan, Sylvie. “Exploring How Musical Rhythm Entrains Brain Activity with Electroencephalogram Frequency-Tagging.” Philosophical Transactions of the Royal Society B 369, no. 1658 (2014). Use as broader rhythm/EEG entrainment support. This helps explain frequency-tagging, beat tracking, meter, neural entrainment, and the measurable relationship between rhythmic structure and brain activity.Thaut, Michael H., Gerald C. McIntosh, and Volker Hoemberg. “Neurobiological Foundations of Neurologic Music Therapy: Rhythmic Entrainment and the Motor System.” Frontiers in Psychology 5 (2015). Use for rhythm as motor-system timing information. This supports the claim that a beat can become bodily instruction, not just sound for the ear. Especially useful when discussing rhythmic auditory stimulation, motor planning, gait, entrainment, and the auditory-motor bridge.Ross, Jessica M., John R. Iversen, and Ramesh Balasubramaniam. “Time Perception for Musical Rhythms: Sensorimotor Perspectives on Entrainment, Simulation, and Prediction.” 2022. Use for rhythm, timing, prediction, sensorimotor entrainment, and the way musical rhythm interacts with time perception.Hove, Michael J., and Jane L. Risen. “It's All in the Timing: Interpersonal Synchrony Increases Affiliation.” Social Cognition 27, no. 6 (2009): 949–960. Use for synchrony and social bonding. This helps support the group-body argument: moving or acting in time with others can increase affiliation.Wiltermuth, Scott S., and Chip Heath. “Synchrony and Cooperation.” Psychological Science 20, no. 1 (2009): 1–5. Use for the claim that synchronized movement can increase cooperation and attachment among participants.Tarr, Bronwyn, Jacques Launay, and Robin I. M. Dunbar. “Music and Social Bonding: ‘Self-Other' Merging and Neurohormonal Mechanisms.” Frontiers in Psychology 5 (2014): 1096. Use for music, synchrony, bonding, endorphin/social mechanisms, and why group rhythm can feel like more than private listening.Fancourt, Daisy, Rosie Perkins, Sara Ascenso, Louise Atkins, Fatima Kilfeather, and Aaron Williamon. “Effects of Group Drumming Interventions on Anxiety, Depression, Social Resilience and Inflammatory Immune Response among Mental Health Service Users.” PLOS ONE 11, no. 3 (2016): e0151136. Use for modern group-drumming research showing psychological and physiological effects, including anxiety, depression, social resilience, wellbeing, and inflammatory immune response. Use carefully: this does not make group drumming a cure-all. It supports the more grounded claim that embodied rhythm and group participation can affect mood, social connection, and body chemistry.Bittman, Barry B., et al. “Composite Effects of Group Drumming Music Therapy on Modulation of Neuroendocrine-Immune Parameters in Normal Subjects.” Alternative Therapies in Health and Medicine 7, no. 1 (2001): 38–47. Use as older supporting material on group drumming and neuroendocrine-immune measures. Keep secondary. Fancourt is cleaner for the main script body.Archaeology and Deep History of DrumsLawergren, Bo. “Neolithic Drums in China.” In Music Archaeology in China. 2006. Use for clay drums in Neolithic China and the deep-history claim that drums are not just poetic symbols of antiquity. They appear in the archaeological record as instruments tied to early sound-making, ceremony, and social order.Both, Arnd Adje. “Music Archaeology: Some Methodological and Theoretical Considerations.” Use as general support for why ancient instruments should be treated as ritual and social evidence, not merely decorative objects.Anthropology, Ethnomusicology, Ritual, and TranceRouget, Gilbert. Music and Trance: A Theory of the Relations Between Music and Possession. Translated by Brunhilde Biebuyck. Chicago: University of Chicago Press, 1985. Essential source. Use for the caution that music does not mechanically or universally cause trance. Rouget helps keep the argument academically serious by emphasizing culture, ritual frame, meaning, and expectation.Becker, Judith. Deep Listeners: MAlso want to remind people about the website, if you're into reading we have tons of information by multiple contributors, and we got t-shirts up on the site if you're interested. Fun fact, the art is all based on the eyeball. A

music health china anxiety phd depression predictions brain fun psychology medicine institute journal essential effects indigenous consciousness ritual neuroscience sees sciences mechanics possession anthropology meter simulation becker rooms cooperation kumar archaeology frontiers merging initiation magick american journal dunbar drumming eeg michael j neurobiology maurer dark room annals bronwyn psychological science tagging scotts chicago press light part landau plos one altered states transpersonal psychology hove woodside tarr modulation yoel human biology new york academy scientific reports alternative therapies michael h chip heath ethnomusicology synchrony emma r maxfield clinical hypnosis entrainment chicago university deep history float tanks social cognition time perception neher royal society b philosophical transactions rouget bittman jessica m human neuroscience clinical neurophysiology isabelle peretz

Treat Non-Severe PreE with BP Meds?

Psychoanalysis On and Off the Couch

Play Episode Listen Later May 31, 2026 15:15

Welcome back, everyone. Today we're diving into one of the most hotly debated topics in obstetrics- should we be treating preeclampsia without severe features with antihypertensive medications during expectant management? Now, if you've been following the literature- and our show, you know that the landmark CHAP trial changed the game for chronic hypertension in pregnancy. It showed us that targeting a blood pressure below 140 over 90 reduces serious maternal complications, without harming the baby. That was a big deal. But here's the thing, CHAP studied chronic hypertension. Then there was the CHIP trial- that also found that tight control of gestational hypertension and nonproteinuric chronic hypertension was also beneficial. These did not address preeclampsia without severe features, and yet, the ripple effects of that trial have sparked a global conversation about whether we should be extending those same treatment principles to women with preeclampsia who don't yet have severe features. And this is where it gets really interesting, because the guidelines don't agree. In the United States, ACOG and the Society for Maternal-Fetal Medicine still say: hold off on antihypertensives unless blood pressures hit the severe range at 160/110. But step outside the US, and you'll find the World Health Organization, the International Society for the Study of Hypertension in Pregnancy, FIGO, NICE, and Hypertension Canada all recommending treatment at 140 over 90, regardless of whether the diagnosis is chronic hypertension, gestational hypertension, or preeclampsia. So who's right? And more importantly what does this mean for the patient sitting in front of you right now, at 34 weeks, with a blood pressure of 150 over 95, some proteinuria, but no severe features? Today, we're going to break this down. We'll review the controversy, walk through the divergent guidelines, and most importantly talk about the real, practical implications that favor treating these patients during expectant management. Because when you're watching someone with preeclampsia, waiting for the right time to deliver, there's a strong argument that controlling their blood pressure isn't just reasonable…may be protective. So grab your coffee, settle in, and let's get into it.1. Society for Maternal-Fetal Medicine Statement: Antihypertensive Therapy For mild chronic Hypertension in Pregnancy-The Chronic Hypertension And Pregnancy Trial. American Journal of Obstetrics and Gynecology. 2022. Society for Maternal-Fetal Medicine; Publications Committee. 2. Preeclampsia. The New England Journal of Medicine. 2022. Magee LA, Nicolaides KH, von Dadelszen P.3. Antihypertensive Drug Therapy for Mild to Moderate Hypertension During Pregnancy.The Cochrane Database of Systematic Reviews. 2018. Abalos E, Duley L, Steyn DW, C.4. Prevention and Treatment of Maternal Stroke in Pregnancy and Postpartum: A Scientific Statement From the American Heart Association. Stroke. 2026. Miller EC, Bello NA, Chen PR, et al.5.Hypertension in Pregnancy: Diagnosis, Blood Pressure Goals, and Pharmacotherapy: A Scientific Statement From the American Heart Association. Hypertension. 2022. Garovic VD, Dechend R, Easterling T, et al.

AI, Subjectivity and Psychoanalysis with Amy Levy, PhD (Chapel Hill, North Carolina)

Play Episode Listen Later May 31, 2026 56:17

"Humanism has been the dominant Western belief system of the last century. It's based on the worship of human wisdom, human creation, human experience, human mind, and psychoanalysis has very much emerged from this humanist tradition. We believe in psychoanalysis, that delving into our feelings, our thoughts, and our shared wisdom will allow us to access truth and meaning and find proper direction for navigating life. AI is changing all of that. Instead of trusting our feelings and our thoughts, people are turning to algorithms to make meaning of our experiences and to offer us direction. We're plugging in our data and allowing the algorithms, or Chat GPT or Claude, to do the thinking and the decision making for us." Episode Description: We begin with Freud in 1930: "Humanity would proceed to create unimaginably great advances in technology so as to increase our likeness to God." Amy outlines the challenge that AI poses to our humanistic tradition and values within which psychoanalysis makes its home. She starts with the 'cult grooming' aspects of smartphones, which introduces our exchanging "human dependence for AI companionship." The question of the subjectivity of AI is a central focus, with some analysts emphasizing its "simulation of human intimacy" and others considering that "is it not also possible for AIs to at the same time be intersubjectively engaged with us?" Regarding using AIs as a therapist, we discuss the clinical implications of "without there being two bodies in a room, the contact is shallow and lacking an essential human component." Amy describes "a desire for transgression" involving AIs as well as the associated search for immortality that they represent. She writes about Bach's prescient 2008 term of "digital consciousness" as contrasted with the "analog watch where one can see the hour from which the hand has come and the hour to which it is going." Amy shares that it was fear that motivated her personal interest in the AI world we are facing, and she closes with, "And how do we address what we are losing from within psychoanalysis?" Our Guest: Amy Levy, PhD, is a clinical psychologist and psychoanalyst. She chairs the American Psychoanalytic Association President's Commission on Artificial Intelligence, serves on the subcommittee "Artificial Intelligence" for the International Psychoanalytical Association, serves on the editorial board of The Psychoanalytic Quarterly, and is Editor of the Substack series, "AI in My Mind," for The Psychoanalytic Quarterly. Along with her fellow CAI chair, Todd Essig, she is producing a documentary film for APsA which examines AI from a psychoanalytic perspective for the general public, entitled: Uncharted Territory: Humans and the Rise of AI. Dr. Levy is in private practice in Chapel Hill, North Carolina. She is the author of the 2026 book, The New Other: Alien Intelligence and the Innovation Drive. Recommended Readings: Harari, Y. N. (2017). Homo Deus: A Brief History of Tomorrow. New York: HarperCollins. Knafo, D. (2024). Artificial intelligence on the couch: Staying human post-AI. American Journal of Psychoanalysis, 84: 155–180. Lemma, A. (2024). Mourning, melancholia, and machines: An applied psychoanalytic investigation of mourning in the age of griefbots. International Journal of Psychoanalysis, 105(4): 542–563. Shelley, M. (2003). Frankenstein. Penguin Classics. Solms, M. (2021a). The Hidden Spring: A Journey to the Source of Consciousness. New York: W. W. Norton. Suleyman, M. (2023). The Coming Wave: Technology, Power, and the 21st Century's Greatest Dilemma. New York: Crown.

god ai power phd western north carolina staying chatgpt humanity artificial intelligence consciousness commission substack artificial frankenstein bach mourning freud levy norton chapel hill international journal american journal humanism psychoanalysis my mind cai subjectivity penguin classics lemma suleyman homo deus a brief history apsa chapel hill north carolina hidden spring a journey

Cardiometabolic Disease In Women XXVII 29May26 Authentic Biochemistry Podcast Dr. Daniel J Guerra

Authentic Biochemistry

Play Episode Listen Later May 29, 2026 65:40

ReferencesJACC Cardiovasc Interv.2025 Apr 28;18(8):963-971Handb Exp Pharmacol. 2014:222:129-56. American Journal of Physiology-Cell Physiology 2009 297:5, C1263-C1274 10.1152/ajpcell.00109Mol Biol Cell. 2014 Sep 15;25(18):2677–2681.Leuk Lymphoma. 2019 Jan 2;60(6):1557–1562Guerra, DJ.2026. Unpublished Lectures.Hunter/ Garcia. 1974. Cruel White Water. Tiger Rose lp. https://open.spotify.com/track/6IzZ1u1D2hW5cv6KPxaKcO?si=065029cd691247ca

women dj disease authentic guerra biochemistry american journal xxvii podcast dr daniel j

The WILDCARD: LUS Window on Prenatal Sono, TOLAC?

phd studies reveal gaps detection american journal food insecurity predictors managed care elevance health

Play Episode Listen Later May 28, 2026 17:26

The American College of Obstetricians and Gynecologists (ACOG) does not recommend routine ultrasound measurement of the lower uterine segment (LUS) thickness as part of the evaluation for trial of labor after cesarean delivery (TOLAC). ACOG Practice Bulletin No. 205 (2019) on Vaginal Birth After Cesarean Delivery does not include LUS measurement among its recommendations for TOLAC candidacy assessment. The guideline focuses on clinical factors such as type of prior uterine incision, number of prior cesarean deliveries, and other obstetric history to determine TOLAC candidacy, and emphasizes that most women with one previous low-transverse cesarean delivery should be counseled about and offered TOLAC. But what if you find a likely uterine window at the LUS? Does that mandate a repeat C-section? This topic comes from Serena, one of our podcast family members. Listen in for details. 1. Dr. Chapa's Clinical Pearls, Dec 31., 2023: LUST FOR TOLAC; and follow up episode Jan 15, 20242. ACOG Practice Bulletin No. 205: Vaginal Birth After Cesarean Delivery. Committee on Practice Bulletins—Obstetrics Obstetrics and Gynecology. 2019;133(2):e110-e127. doi:10.1097/AOG.0000000000003078.3. Rozenberg P, Sénat MV, Deruelle P, et al. Evaluation of the Usefulness of Ultrasound Measurement of the Lower Uterine Segment Before Delivery of Women With a Prior Cesarean Delivery: A Randomized Trial. American Journal of Obstetrics and Gynecology. 2022. 4. Swift BE, Shah PS, Farine D. Sonographic Lower Uterine Segment Thickness After Prior Cesarean Section to Predict Uterine Rupture: A Systematic Review and Meta-Analysis. Acta Obstetricia Et Gynecologica Scandinavica. 2019. 5. McLeish SF, Murchison AB, Smith DM, et al. Predicting Uterine Rupture Risk Using Lower Uterine Segment Measurement During Pregnancy With Cesarean History: How Reliable Is It? A Review. Obstetrical & Gynecological Survey. 2023. 6. Jastrow N, Demers S, Chaillet N, et al. Lower Uterine Segment Thickness to Prevent Uterine Rupture and Adverse Perinatal Outcomes: A Multicenter Prospective study.7. American Journal of Obstetrics and Gynecology. 2016. 8. Guerby P, Bujold E, Chaillet N. Impact of Third-Trimester Measurement of Low Uterine Segment Thickness and Estimated Fetal Weight on Perinatal Morbidity in Women With Prior Cesarean Delivery. Journal of Obstetrics and Gynaecology Canada. JOGC. 2022.

impact journal window committee wild card evaluation sono american colleges american journal obstetrics prenatal gynecology mv obstetricians meta analysis usefulness chapa lus aog clinical pearls gynecologists acog obstetrical

Food Insecurity Studies Reveal Key Predictors, Detection Gaps: Jonathan Wrathall, PhD

Managed Care Cast

Play Episode Listen Later May 26, 2026 15:34

On this episode of Managed Care Cast, The American Journal of Managed Care® spoke with Jonathan Wrathall, PhD, a senior advanced analytics consultant at Elevance Health. He authored 2 studies published in the May 2026 issue, both of which centered on food insecurity: “Food Insecurity Identification Modeling for Medicare Enrollees Using Administrative Data” and “Making the Most of Limited Resources: Predicting Food Insecurity.” Throughout the conversation, Wrathall highlighted the motivation behind his studies, key food insecurity predictors, unexpected findings, and gaps in identifying needs across insurance groups. Before concluding, he rounded out the discussion by bringing the findings of both studies together to explain their implications for improving food insecurity detection in health systems.

Carlos Juan Finlay and Yellow Fever

Play Episode Listen Later May 25, 2026 41:41 Transcription Available

Carlos Juan Finlay was a Cuban doctor who did a lot of work to understand the spread of Yellow Fever. But Walter Reed got most of the credit. Research: American Experience. “Carlos Finlay (1833-1915).” From The Great Fever. PBS. https://www.pbs.org/wgbh/americanexperience/features/fever-carlos-finlay/ Berenbrok, Dorothy E., "Latin Heritage Month. Carlos Juan Finlay: Outrageous, Courageous and Correct" (2015). Posters: Jefferson History. 3. https://jdc.jefferson.edu/jeffhistoryposters/3 "Carlos Juan Finlay." Encyclopedia of World Biography Online, Gale, 1998. Gale In Context: Opposing Viewpoints, link.gale.com/apps/doc/K1631002194/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=bfeecc25. Accessed 29 Apr. 2026. Chaves-Carballo, Enrique. “Carlos J. Finlay: The mosquito man.” Hektoen International. 11/2/2020. https://hekint.org/2020/11/02/carlos-j-finlay-the-mosquito-man/ Corbitt, Duvon C. “Carlos J. Finlay, Cuban Physician.” The Hispanic American Historical Review, Vol. 45, No. 3 (Aug., 1965). Via JSTOR. https://www.jstor.org/stable/2511751 Del Regato, Juan A. “Carlos Juan Finlay (1833-1915).” Journal of Public Health Policy , 2001, Vol. 22, No. 1 (2001). Via JSTOR. https://www.jstor.org/stable/3343556 Faerstein, Eduardoa; Winkelstein, Warren Jrb. Carlos Juan Finlay: Rejected, Respected, and Right. Epidemiology 21(1):p 158, January 2010. | DOI: 10.1097/EDE.0b013e3181c308e0 Ferreira Moreno, Víctor Guillermo. “Evocation to the Dr. Carlos J. Finlay Barres on the centennial of his death.” Colombia medica (Cali, Colombia) vol. 47,1 63-6. 30 Mar. 2016 Finlay, Carlos J. “The Mosquito Hypothetically Considered as the Agent of Transmission of Yellow Fever.” Read before the Royal Academy of Medical, Physical and Natural Sciences Session of August 14th, 1881. https://archive.org/details/b33448541/page/590/mode/1up Finlay, Carlos Juan. “Trabajos selectos del Dr. Carlos J. Finlay. Selected papers of Dr. Carlos J. Finlay.” Habana. 1912. https://archive.org/details/trabajosselectos00finl Finlay, Charles. “Inoculations for Yellow Fever by Means of Contaminated Mosquitoes.” Published in The American Journal of the Medical Sciences, n.s. 102: 264-268, 1891. https://archive.org/details/b33445242/page/n4/mode/1up Finlay, Charles. “Yellow Fever: Its ‘Transmission by Means of the Culex Mosquito.” Published in The American Journal of the Medical Sciences, n.s. 92: 395-409, 1886. https://archive.org/details/b33435698/page/613/mode/1up Palmer, Steven. “A Cuban Scientist Between Empires: Peripheral Vision on Race and Tropical Medicine.” Canadian Journal of Latin American and Caribbean Studies / Revue canadienne desétudes latino-américaines et caraïbes, Vol. 35, No. 69, Special Issue: Landscapes of LatinAmerican Health, 1870-1970. Via JSTOR. https://www.jstor.org/stable/41800498 Spears, Ellen Griffith and Rosa López-Oceguera. “Carlos Juan Finlay, William Gorgas, and Walter Reed and the U.S. Army Yellow Fever Controversy: Competing Historical Memories.” Alabama Review The University of Alabama Press. Volume 74, Number 1, January 2021. https://doi.org/10.1353/ala.2021.0011 Stepan, Nancy. “The Interplay between Socio-Economic Factors and Medical Science: Yellow Fever Research, Cuba and the United States.” Social Studies of Science , Nov., 1978, Vol. 8, No. 4 (Nov., 1978). Via JSTOR. http://www.jstor.com/stable/284817 Thomas Jefferson University. “10 Notable Jefferson Alumni of the Past.” https://library.jefferson.edu/archives/exhibits/notable_alumni/juan_carlos_finlay.cfm Tone, John Lawrence. (2002) “How the mosquito (man) liberated Cuba.” History and Technology, 18:4, 277-308, DOI: 10.1080/07341512.2002.11417735 “Carlos J. Finlay.” 5/16/2023. https://www.unesco.org/en/prizes/carlos-j-finlay/about Woodall, Jack. "Yellow Fever." Infectious Diseases: In Context, edited by Brenda Wilmoth Lerner and K. Lee Lerner, vol. 2, Gale, 2008, pp. 925-931. In Context Series. Gale In Context: Opposing Viewpoints, link.gale.com/apps/doc/CX3045200265/GPS?u=mlin_n_melpub&sid=bookmark-GPS&xid=bf646a26. Accessed 29 Apr. 2026. See omnystudio.com/listener for privacy information.

The Mechanics of Magick: Singing Bowls and the Ritual Physics of Resonance

The Race and Rights Podcast

Play Episode Listen Later May 25, 2026 97:35 Transcription Available

If you enjoy this episode, we're sure you will enjoy more content like this on The Occult Rejects. In fact, we have curated playlists on occult topics like grimoires, esoteric concepts and phenomena, occult history, analyzing true crime and cults with an occult lens, Para politics, and occultism in music. Whether you enjoy consuming your content visually or via audio, we've got you covered - and it will always be provided free of charge. So, if you enjoy what we do and want to support our work of providing accessible, free content on various platforms, please consider making a donation to the links provided below. Thank you and enjoy the episode!Links For The Occult Rejectshttps://linktr.ee/theoccultrejectsOccult Research Institutehttps://www.occultresearchinstitute.org/Cash Apphttps://cash.app/$theoccultrejectsVenmo@TheOccultRejectsBuy Me A Coffeebuymeacoffee.com/TheOccultRejectsPatreonhttps://www.patreon.com/TheOccultRejectsBibliographyThe Mechanics of Magick: Singing Bowls and the Ritual Physics of ResonanceCore Singing Bowl ResearchStanhope, Jessica, and Philip Weinstein. “The Human Health Effects of Singing Bowls: A Systematic Review.” Complementary Therapies in Medicine 51 (2020): 102412. Use for the honesty frame: promising findings around mental health and cardiovascular measures, but limited evidence and need for stronger study design.Cai, Yiqing, Guo-Yan Yang, Yibo Liu, Xiang-yun Zou, Heng Yin, Xinyan Jin, Xue-han Liu, Chenlu Wang, Nicola Robinson, and Jian-Ping Liu. “Therapeutic Effects of Singing Bowls: A Systematic Review of Clinical Studies.” Integrative Medicine Research 14, no. 2 (2025): 101144. Use for the newer clinical overview. Important correction: this appears as 101144, not 101176. Good for anxiety, depression, sleep quality, cognition, autistic behavior, and EEG-related outcomes while still keeping the evidence cautious.Lin, F. W., et al. “Effects of Tibetan Singing Bowl Intervention on Psychological and Physiological Health in Adults: A Systematic Review.” 2025. Useful as another recent review angle, especially for psychological health, physiological measures, HRV, and brainwave-related discussion. Keep it secondary behind Stanhope and Cai.Landry, Jayan Marie. “Physiological and Psychological Effects of a Himalayan Singing Bowl in Meditation Practice: A Quantitative Analysis.” American Journal of Health Promotion 28, no. 5 (2014): 306–309. Use for the controlled relaxation study: 51 participants, randomized crossover design, singing bowl exposure or silence before directed relaxation.Goldsby, Tamara L., Michael E. Goldsby, Mary McWalters, and Paul J. Mills. “Effects of Singing Bowl Sound Meditation on Mood, Tension, and Well-Being: An Observational Study.” Journal of Evidence-Based Complementary & Alternative Medicine 22, no. 3 (2017): 401–406. Use for reductions in tension, anger, fatigue, depressed mood, anxiety, and stress after singing bowl meditation. Good, but frame as observational, not definitive.Rio-Alamos, Cristina, et al. “Acute Relaxation Response Induced by Tibetan Singing Bowl Sounds: A Randomized Controlled Trial.” European Journal of Investigation in Health, Psychology and Education 13, no. 2 (2023): 317–328. Use for Tibetan singing bowl treatment compared with progressive muscle relaxation and a waiting-list control in anxious nonclinical adults.Walter, Nina, et al. “Neurophysiological Effects of a Singing Bowl Massage.” Medicina 58, no. 5 (2022): 594. Use for EEG, ECG, and respiration during singing bowl massage; the authors interpret the results as a shift toward a more mindful or meditative state.Goldsby, Tamara L., et al. “Mood, Emotional, and Spiritual Well-Being Interrelationships.” Religions 13, no. 2 (2022). Useful follow-up for spiritual well-being, emotional interpretation, and how people understand sound-healing experiences.Sound, Anxiety, HRV, and Brainwave CautionMallik, Adiel, and Frank A. Russo. “The Effects of Music & Auditory Beat Stimulation on Anxiety: A Randomized Clinical Trial.” PLOS ONE 17, no. 3 (2022): e0259312. Use this carefully for the broader point that sound-based treatments can reduce somatic and cognitive state anxiety. Do not use it as proof that singing bowls automatically entrain brainwaves.Ingendoh, Ruth Maria, Ella S. Posny, and Angela Heine. “Binaural Beats to Entrain the Brain? A Systematic Review of the Effects of Binaural Beat Stimulation on Brain Oscillatory Activity, and the Implications for Psychological Research and Intervention.” PLOS ONE 18, no. 5 (2023): e0286023. Very useful caution source. Use it when warning against overclaiming “brainwave entrainment” and frequency-healing claims.Vilímek, et al. 2022. Low-frequency sound / HRV / vibroacoustic-related research. Use cautiously if you want to discuss low-frequency vibration, body sensation, and autonomic response. I'd keep this as a secondary source unless you want a dedicated paragraph on vibroacoustics.Physics, Resonance, and CymaticsTerwagne, Denis, and John W. M. Bush. “Tibetan Singing Bowls.” Nonlinearity 24, no. 8 (2011): R51–R66. Use for the physics section: wall vibrations, water-surface waves, Faraday-wave effects, droplet motion, and the visible demonstration of resonance.Jenny, Hans. Cymatics: A Study of Wave Phenomena and Vibration. Newmarket, NH: MACROmedia, 2001. Use carefully for visual sound-pattern history. Good for imagery and occult imagination, but don't overuse it as clinical proof.Rossing, Thomas D. The Science of Sound. 3rd ed. San Francisco: Addison Wesley, 2002. Useful general acoustics source for resonance, overtones, vibration, sound waves, and instrument physics.Sound Baths, Wellness Culture, and Modern RitualSobo, Elisa J. “Sound Baths, Trauma Talk, and the Wellness Paradox in the USA.” Medical Anthropology 43, no. 5 (2024): 367–382. Excellent for the modern sound-bath/wellness-culture angle, especially trauma language, nervous-system talk, ritual performance, and how providers frame sound baths.Sobo, Elisa J. “A Beginner's Guide to Sound Baths — What They Are, How to Choose a Good One and What the Research Shows.” The Conversation (2024). Useful for accessible show-note language and ethical/practical framing.Sobo, Elisa J. “Healing Vibrations.” Anthropology News 64, no. 5 (2023): 28–32, 49. Good anthropology/public-facing source for sound healing and wellness culture.Tibetan Singing Bowls, History, and Cultural CommodificationGrimes, Samuel. “Where Did ‘Tibetan' Singing Bowls Really Come From?” Tricycle (2020). Use for the contested-history section. Strong source for questioning popular origin stories around “Tibetan” singing bowls.Joffe, Ben. “Anthropology and Tibetan Buddhism / Cultural Commodification / Tibetan Mystique.” 2015. Use for the larger argument about how Tibetan/Himalayan aura gets packaged in Western spiritual markets. Good support for the “Tibet as imagined storehouse of hidden wisdom” point.Scheidegger, Daniel A. “Tibetan Ritual Music.” Use for actual Tibetan Buddhist ritual sound: bells, cymbals, long horns, drums, chant, and liturgical soundscape. This helps separate real Tibetan ritual sound from overblown modern singing-bowl mythology.Lopez, Donald S. Prisoners of Shangri-La: Tibetan Buddhism and the West. Chicago: University of Chicago Press, 1998. Excellent support for Western romanticization of Tibet.Bishop, Peter. The Myth of Shangri-La: Tibet, Travel Writing, and the Western Creation of Sacred Landscape. Berkeley: University of California Press, 1989. Very useful for the “Tibet as fantasy geography” angle.Ritual, Sound, and Religious ExperienceEliade, Mircea. Shamanism: Archaic Techniques of Ecstasy. Princeton: Princeton University Press, 1964. Use carefully. Good for altered-state technologies and ritual sound/trance, but don't treat it as the final word on shamanism.Rouget, Gilbert. Music and Trance: A Theory of the Relations Between Music and Possession. Chicago: University of Chicago Press, 1985. Excellent for sound, music, trance, possession, rhythm, and ritual performance.Becker, Judith. Deep Listeners: Music, Emotion, and Trancing. Bloomington: Indiana University Press, 2004. Strong source for deep listening, music, emotion, trance, and the body.Husserl, Edmund. On the Phenomenology of the Consciousness of Internal Time. Useful if you want to get philosophical about tone, decay, waiting, and how sound reveals time.Ihde, Don. Listening and Voice: Phenomenologies of Sound. Albany: SUNY Press, 2007. Good for sound as experience, listening, voice, and embodied perception.Placebo, Meaning Response, and Healing RitualMoerman, Daniel E. Meaning, Medicine and the “Placebo Effect.” Cambridge: Cambridge University Press, 2002. Use for “meaning response” instead of treating placebo as “fake.”Benedetti, Fabrizio. Placebo Effects: Understanding the Mechanisms in Health and Disease. Oxford: Oxford University Press, 2009. Useful for placebo mechanisms, expectation, physiology, and therapeutic context.Kaptchuk, Ted J., and Franklin G. Miller. “Placebo Effects in Medicine.” New England Journal of Medicine 373 (2015): 8–9. Good short medical source for placebo effects as real psychobiological phenomena.Csordas, Thomas J. The Sacred Self: A Cultural Phenomenology of Charismatic Healing. Berkeley: University of California Press, 1994. Useful for healing, embodiment, ritual, and religious experience.Embodied Cognition, Extended Mind, and Ritual ToolsClAlso want to remind people about the website, if you're into reading we have tons of information by multiple contributors, and we got t-shirts up on the site if you're interested. Fun fact, the art is all based on the eyeball. A

united states music history health conversations education guide anxiety sound west religion brain fun psychology western medicine emotional myth journal disease effects bush consciousness emotion ritual mood hans implications investigation tension physics psychological lopez intervention mechanics possession denis anthropology medicina becker tibet vibration placebos tibetans ecstasy vil resonance magick american journal mechanisms edmund liu hrv alternative medicine new england journal eeg fabrizio good one newmarket physiological chicago press zou ecg health promotion tibetan buddhists cai california press faraday european journal plos one placebo effect phenomenology systematic review binaural beats benedetti tricycle travel writing joffe singing bowls stanhope psychological effects mircea xiang sobo medical anthropology sound baths husserl cambridge cambridge university press oxford oxford university press chicago university berkeley university clinical studies complementary therapies tibetan singing bowls embodied cognition adiel psychological research goldsby rouget entrain xue occult rejects placebo effects rossing paul j mills

Zeit für uns - können gute Hobbys glücklich machen?

Betreutes Fühlen

Play Episode Listen Later May 25, 2026 77:24 Transcription Available

Sie sind so wichtig für unsere psychische Gesundheit, und doch vernachlässigen wir Hobbys oft. Aber was hält uns eigentlich auf: Keine Zeit, noch nicht das richtige gefunden - oder vielleicht die Angst, nicht gut genug zu sein? Leon und Atze sprechen heute darüber, warum die besten Hobbys merkwürdig sind, wieso wir uns mehr Mittelmäßigkeit zutrauen sollten, und wie man das passende Hobby für sich findet. Fühlt euch gut betreut Leon & Atze Instagram: https://www.instagram.com/leonwindscheid/ https://www.instagram.com/atzeschroeder_offiziell/ Mehr zu unseren Werbepartnern findet ihr hier: https://linktr.ee/betreutesfuehlen Tickets: Atze: https://www.atzeschroeder.de/#termine Leon: https://leonwindscheid.de/tour/ Quellen Was die Deutschen in ihrer Freizeit machen, lässt sich im “Freizeitmonitor 2025” nachlesen: https://www.stiftungfuerzukunftsfragen.de/freizeit-monitor-2025/ Das Paper des amerikanischen Psychiaters über Hobbys während des zweiten Weltkriegs: Menninger, W. C. (1942). Psychological aspects of hobbies: A contribution to civilian morale. American Journal of Psychiatry, 99(1), 122-129. In der Süddeutschen Zeitung schreibt Christina Berndt über Hobbys: https://www.sueddeutsche.de/wissen/hobbys-glueck-arbeit-vorbild-freizeit-li.3325267?reduced=tr Die Idee der “atelischen” Aktivitäten stammt von dem Philosophen Kieran Setiva, nachzulesen im Buch “4000 Wochen: Das Leben ist zu kurz für Zeitmanagement” von Oliver Burkeman Das Review zu Hobbys: Fancourt, D., Aughterson, H., Finn, S., Walker, E., & Steptoe, A. (2021). How leisure activities affect health: a narrative review and multi-level theoretical framework of mechanisms of action. The Lancet Psychiatry, 8(4), 329-339. Die Längsschnittstudie zum Effekt von Hobbys auf Depressionen: Fancourt, D., Opher, S., & de Oliveira, C. (2020). Fixed-effects analyses of time-varying associations between hobbies and depression in a longitudinal cohort study: support for social prescribing?. Psychotherapy and Psychosomatics, 89(2), 111-113. Das Review zur Wirksamkeit von Verhaltensaktivierung bei Depression: Uphoff, E., Ekers, D., Robertson, L., Dawson, S., Sanger, E., South, E., ... & Churchill, R. (2020). Behavioural activation therapy for depression in adults. Cochrane Database of Systematic Reviews, (7). Von der “grindification” der Hobbys spricht der Youtuber “Alastair” in diesem Video: https://www.youtube.com/watch?v=UHAqhP8EeYQ Die Verteidigung der Mittelmäßigkeit von Tim Wu in der New York Times: https://www.nytimes.com/2018/09/29/opinion/sunday/in-praise-of-mediocrity.html Zum Trend der “cozy” Hobbys im Guardian: https://www.theguardian.com/lifeandstyle/2025/sep/04/crafts-are-like-medicine-gen-z-and-the-rapid-rise-of-cosy-hobbies The Atlantic über Produktivität von Hobbys: https://www.theatlantic.com/family/archive/2022/01/history-hobbies-america-productivity-leisure/621150/ Goethe-Institut über den Hobby-Boom während der Pandemie: https://www.goethe.de/prj/mis/de/lei/21904663.html Redaktion: Mia Mertens Produktion: Murmel Productions

159: Prenatal Strength Training: Benefits Beyond Birth (Yes, You Can Lift!)

The MamasteFit Podcast

Play Episode Listen Later May 20, 2026 25:30

Gina, a perinatal fitness trainer, birth doula, and founder of MamasteFit in North Carolina, explains how exercising during pregnancy improves quality of life during pregnancy and postpartum—not just birth outcomes—while noting prenatal exercise research is still limited. She highlights a 2025/2026 American Journal of Obstetrics and Gynecology systematic review (11 RCTs) finding the strongest biomarker benefits from 12+ week programs done 2–3 times/week at moderate-to-vigorous intensity, including reduced pro-inflammatory markers, improved glucose/insulin regulation (supporting lower gestational diabetes risk), better lipid regulation, and favorable hormone/growth-factor changes linked to placental function and possibly baby brain development. Another 2025 review (9 RCTs, 1,500+ participants) suggests strength training may reduce excessive weight gain, low back/sciatic pain, and improve mood, sleep, fatigue, and well-being. She also cites studies indicating high-intensity lifting and even Valsalva can be well-tolerated with adequate rest and self-monitoring, then outlines MamasteFit's endurance-focused programming (compound lifts, accessory multi-plane work, myofascial slings, and posterior-chain emphasis) and promotes their app/video programs with a discount code.00:00 Why Prenatal Exercise Matters00:46 Meet Gina and MamasteFit01:38 What Research Can Tell Us02:23 Biomarkers and Training Dose05:11 Inflammation and Glucose Control08:05 Lipids Hormones and Baby Brain10:46 Strength Training Quality of Life13:17 Heavy Lifting and Valsalva Safety18:03 Listening to Your Body18:58 How to Program Prenatal Lifting20:54 Movement Variety and Posterior Chain23:04 Programs and Final Takeaways————

babies training benefits north carolina programs lift supplements inflammation strength training american journal obstetrics maternity prenatal gynecology biomarkers heavy lifting rcts start preparing valsalva beyond birth

Episode 265 – The Future of Healing: How Exosomes Re-Educate Your Body to Heal Itself

Let's Talk Wellness Now

Play Episode Listen Later May 20, 2026 51:27

Dr. Deb Muth 00:04What if the future of healing isn’t about replacing cells, but about teaching your body how to heal itself again? We keep hearing the words stem cells and exoomes thrown around like they’re interchangeable, but they’re not. One is regulated, controversial, and often misunderstood. The other is rapidly emerging as one of the most exciting communication systems in human biology. Dr. Deb Muth 00:33And here’s the real question no one’s asking. Are we actually regenerating tissue or are we just stimulating the body to remember how it used to heal? Tired of being told your labs are normal, but you still feel terrible? At Serenity Healthcare Center, we don’t chase symptoms. We find the root cause. hormones, gut health, autoimmune conditions, chronic fatigue, brain fog. Dr. Deb Muth 01:02We use cuttingedge functional and regenerative medicine to get you real answers and a real path forward. This isn’t your average doctor’s office. This is medicine the way it was meant to be practiced. You deserve to feel like yourself again. Visit serenityhealthcarecenter.com to book your appointment today. Let us help you heal from the inside out. Dr. Deb Muth 01:28Welcome back to Let’s Talk Wellness Now. I’m Dr. Deb, your host. And if you’ve been following regenerative medicine, you’ve probably noticed the confusion. Patients are asking me every week, are exoomes stem cells? Are stem cells legal in the United States? I heard the FDA is shutting down all these clinics. Can I even get this therapy? Do I have to leave the country for treatment? Today, we’re cutting through the noise. This episode is not hype. Dr. Deb Muth 01:54It’s not sales. It’s education so you can understand the science, the regulatory reality, and the clinical difference between stem cell therapy and exoome therapy. And here’s what I want you to know right up front. Yes, these therapies are being used in the United States every single day. Yes, they’re being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 02:22Some are being used in FDA registered clinical trials. Some are being used in observational studies and some are being used in clinical practice under physician discretion. The landscape is nuanced and you deserve to understand it. So, grab your cup of coffee or tea and settle in for a deep dive into the most understood therapies in regenerative medicine. Dr. Deb Muth 02:43what they actually are, how they work, the regulatory landscape, and how they might support your body’s natural healing capacity. Let’s talk wellness now. So, let me start by asking you something. When you hear the word stem cell, what do you picture? Most people imagine damaged tissues magically regenerating or a torn meniscus growing back, cartilage reforming it into an arthritic joint or damaged brain tissue being replaced with healthy new beautiful cells. It’s a beautiful vision. Dr. Deb Muth 03:15And while it’s not quite that simple, the reality is actually more sophisticated and honestly more beautiful. Stem cells are powerful and they absolutely work, but the way they work and the mechanism by which they support healing is far more elegant and more so than most people really understand. And if you’re going to invest in regenerative therapy, you deserve to understand what you’re actually receiving. Dr. Deb Muth 03:44So, let’s start at the beginning. What are stem cells? At their core, stem cells are undifferentiated cells. That means they haven’t yet decided what they want to be when they grow up. Unlike a heart cell or a skin cell or a bone cell which have already committed to a specific function, stem cells exist in this beautiful state of potential. Dr. Deb Muth 04:05They have two remarkable abilities. First, they can self-renew. They can make copies of themselves, maintaining a reserve of these powerful cells throughout your lifetime. Second, they can differentiate under the right conditions. They can transform into specialized cell types. Bone cells, cartilage cells, nerve cells, muscle cells, even blood cells. Dr. Deb Muth 04:27This is why they’ve captured the imagination of the medical world. The potential is extraordinary. Now, there are several types of stem cells and understanding the differences matters tremendously for both understanding how they work and understanding how they’re regulated. Adult mezzenymal stem cells. We call these MSC’s are the most commonly used regenerative medicine. Dr. Deb Muth 04:54These come from bone marrow, atapost tissue, that’s fat, and other adult sources. They’re what we can call multi-potent, meaning they can become several types of cells, but not every type. A bone marrow stem cell isn’t going to become a brain cell, for instance. It has potential but it’s directed potential. Dr. Deb Muth 05:19Then we have perinatal stem cells. These come from umbilical cord blood cord tissue or something called Wharton’s jelly which is the gelatinous substance inside the umbilical cord. These cells are younger, more potent, and research by Weiss and colleagues published in stem cells back in 2006 showed that Wharton’s jelly derived MSC’s have superior proliferation and differentiation potential compared to bone marrow derived cells. Dr. Deb Muth 05:48They’re like comparing a 20-year-old athlete to a 50-year-old athlete. Both can perform, but one has more reserve capacity, more vigor, and more regenerative potential. And this isn’t this is very important because the perinatal sources umbilical cord tissue Wharton’s jelly amniotic tissue these are what many regenerative medicine clinics in the United States are using today and they’re using them because these tissues are incredibly rich in not just stem cells but growth factors cytoines and exoomes. Dr. Deb Muth 06:21Then there are embryionic stem cells. These are pur potent and they become any cell type in the body, but they’re highly regulated, ethically controversial, and honestly, they’re not being used in clinical practice in the United States outside of the very specific FDA approved research trials. Dr. Deb Muth 06:41So, when clinics talk about stem cell therapy, they’re almost never talking about embryionic stem cells. Now, here’s where it gets interesting and this is the part that changes everything about how we understand regenerative medicine. When you receive stem cell therapy, let’s say someone injects umbilical cord derived messenymal stem cells into your arthritic knee, those cells do not typically engraft or become new tissue in any permanent way. Dr. Deb Muth 07:12They don’t set up shop in your joint and start cracking out new cartilage cells for the rest of your life. So what are they actually doing then? Well, in 2011, researchers Arnold Arnold Kaplan and Dennis Korea published a landmark paper in stem cells translational medicine that fundamentally changed how we understand MSC therapy. Dr. Deb Muth 07:35They proposed that we should stop calling memal stem cells and start calling them medicinal signaling cells. Why? Well, because their primary therapeutic benefit doesn’t come from what they become. It comes from what they secrete. Think of stem cells as incredibly sophisticated biological pharmacies. When you inject them into damaged tissue, that arthritic knee, that inflamed autoimmune condition, that injured brain, that don’t just sit there passively, they sense the environment. Dr. Deb Muth 08:07They detect inflammation. They recognize the tissue damage and they understand that the immune dysregulation is present and they see that and respond. They start pumping out hundreds of bioactive molecules, growth factors that tell your cells to repair and rebuild, cytoines that modulate inflammation, chemocines that recruit your body’s own healing cells to the area. Dr. Deb Muth 08:32And these tiny membranes bound packages called extracellular vesicles, including exosomes, which we’re going to talk about extensively today as well. These secreted factors are giving instructions to your native cells. They’re saying, “Let’s reduce inflammation. Let’s modulate your immune response. Let’s promote angioenesis. Dr. Deb Muth 08:53” That’s the formation of new blood vessels, bringing nutrients and oxygen. Let’s stimulate your own resident stem cells to wake up and get to work. Reduce cell death in damaged tissue and restore normal cellular function. This is called paracrine signaling. It’s the cellto cell communication. And this is where the real therapeutic power lives. Dr. Deb Muth 09:14The stem cells themselves, many of them die within days to weeks, but the cascade of healing they trigger, the signals they send, the programs they activate in your own cells, those effects can last for months or even years. Now, this understanding is crucial because it explains why both stem cell therapy and exoo therapy can be effective. Dr. Deb Muth 09:38The stem cells are powerful not because they become new tissue but because of the signals they send and exoomes are those signals isolated and concentrated. The biggest misconception in regenerative medicine is that stem cells replace tissue and in reality they coach healing more than they become healing. They’re biological educators teaching your body to remember how it used to heal before chronic inflammation, toxicity, and disease turned off all those programs. Dr. Deb Muth 10:12So if stem cells don’t exactly end graft and become the new tissue, if their power is in their signaling and then next logical question is why do we need the cells at all? Well, if we could isolate the messengers themselves, what if we could deliver just the communication systems without any of the complexity of the living cells? Well, that’s exactly what exosomes are. Dr. Deb Muth 10:38And they represent the cutting edge of regenerative medicine. So, let me paint you a picture of how cells actually communicate. Because for most medical history, we had it wrong. For decades, textbooks taught us that cells talk to each other in two basic ways. through direct contact like shaking hands or releasing signaling molecules that floated through the extracellular space like messages in bottles, simple chemical messages. Dr. Deb Muth 11:09But in the 1980s and 90s, researchers started discovering something far more sophisticated. cells were releasing these tiny membrane bound packages like a biological FedEx envelope kind of you know it was filled with complex specific cargo and these packages could travel through the blood cross the barriers that normally keep things out like bloodb brain barrier and deliver their contents to distant cells with remarkable precision. Dr. Deb Muth 11:38These are called extracellular vesicles. And exoomes are one of the most therapeutic important types. So what exactly are exosomes? Well, they’re nanosized vesicles, typically 30 to 150 nanome in diameter. To put that into perspective, a human hair is about 100,000 nanometers wide. These are incredible and most impossibly tiny. Dr. Deb Muth 12:09They’re released by virtually all cells in the body, but the most therapeutically interesting exoomes come from mezenymal stem cells. And those medicinal signaling cells we just discussed. And according to a landmark review of Raposo and Stervogal, they published in the journal of cell biology in 2013, exoomes are not cellular debris. They’re not waste products. Dr. Deb Muth 12:35They are precisely engineered communication vesicles or vehicles. Think of them as sophisticated delivery systems carefully packed, carefully labeled, and sent to specific destinations. very specific instructions. Inside each of these exoomes, you’ll find an incredibly sophisticated payload. They are microRNAs. These are small RNA molecules that can literally turn genes off or on in the recipient cells. Dr. Deb Muth 13:06They can tell a cell to start making more collagen, to reduce inflammatory proteins, to activate repair programs that have been shut down by chronic disease for a very long time. There are messenger RNAs, actual templates for protein production. And exoome can deliver these instructions for making healing proteins. There are proteins themselves, growth factors, cytoines, enzymes, all the molecular tools a cell needs to heal. Dr. Deb Muth 13:34And there are lipids, specialized fats that help the exoome membrane fuse with targeted cells, delivering the cargo inside. When an exoome reaches its target cell, it can either fuse the cell membrane and deliver its contents directly inside like a Trojan horse, or it can bind to surface receptors and trigger signaling cascades, setting off a chain reaction of healing responses. Dr. Deb Muth 14:01Either way, it’s delivering very specific targeted instruction. And here’s what makes this so powerful. Those instructions are tailored to what this recipient cell actually needs. So, let me give you some concrete examples of what the research actually shows because this is where it really gets exciting. When researchers inject MSC derived exoomes into hearts that had experienced eskeeia, reprofusion, injury, that’s damaged blood flow being cut off and then being restored. Dr. Deb Muth 14:36Kind of like what happens during a heart attack. Something remarkable happened. A study by Lei and colleagues published in stem cell research in 2010 showed that exoomes significantly reduced the size of the damaged area, reduced inflammatory cytoines that drive tissue destruction and promoted tissue repair signaling. The exoomes were telling the heart cells stop the inflammatory cascade, activate your survival programs and repair the damage. Dr. Deb Muth 15:06In cartilage research, tow and colleagues published work in biioaterials in 2017 showing that exosomes derived from MSC’s could promote cartilage regeneration in osteoarthritis models. And the exoomes carried specific microRNAs that told condondroytes cartilage cells to proliferate and make more extracellular matrix, the structural framework of healthy cartilage. Dr. Deb Muth 15:30for autoimmune conditions. Research by Blazic and colleagues in Frontiers in Immunology in 2014 demonstrated that MSC derived exoomes could shift immune cell behavior from pro pro-inflammatory to regulatory. They could take an overactive self-attacking immune system and restore balance and promote tolerance. And perhaps most exciting brain research, a study by Zinn and colleagues published in the journal of extracellular vesicles in 2013 showed that MSC derived exoomes could cross the bloodb brain barrier. Dr. Deb Muth 16:07That protective shield around your brain that normally keep things out and promote neurological recovery in stroke models. They reduced brain inflammation, promoted neuroplasticity, supported the formation of neural connections, and for mitochondrial dysfunction, which underlies so many chronic conditions, Morrison and colleagues published research and scientific reports in 2017 showing that MSC derived exoomes can actually deliver functional mitochondria or mitochondrial components to damaged cells. They’re not Dr. Deb Muth 16:40just sending instructions, they’re sending spare parts. They’re restoring the cellular powerhouses to produce energy. So why are exoomes fundamentally different from stem cells? Well, exoomes contain no living cells. They can’t replicate. They can’t end graph. And they have virtually no risk of immune rejection or tumor formation. Dr. Deb Muth 17:03Concerns that exist elevate rarely with cellular therapies. They’re essentially biological software updates for your cells. As Fineian Pitiger wrote in their seinal review in stem cells in 2017, MSC derived exoomes represent the active ingredient of stem cell therapy delivered in a cellfree format. That’s the key insight in the in the therapeutic benefit of stem cells and it comes from what they excrete. Dr. Deb Muth 17:33Then exoomes are the secretion isolated, concentrated, and standardized. From a practical clinical standpoint, exoomes offer several compelling advantages. First, consistency. Because exoomes can be isolated, characterized, and standardized, each dose can be remarkably consistent. With living stem cells, there’s variability based on donor age, health status, processing methods, and one batch may be robust, but another might be weaker. Dr. Deb Muth 18:05With exoomes, you can measure the content, measure the potency, and ensure the quality control. Second is storage. Exoomes can be liophalized. They can be freeze-dried and stored at room temperature or refrigerated for extended periods. Stem cells require cryopreserv preservation, careful freezing, careful thawing. They’re fragile. Dr. Deb Muth 18:31Exoomes are remarkably stable. And third, their safety profile. Without living cells, the risk of adverse imunological reactions is dramatically lower. You’re not introducing foreign cells that your immune system might recognize and attack. You’re introducing molecular messages. Fourth is scalability. You can harvest millions, even billions of exoomes from stem cell cultures without ever injecting the cells themselves. Dr. Deb Muth 19:01And you can produce large quantities, standardize them, and make them available to patients. Now, there is a caution here in doing this. The scalability can produce rogue cells, and we want to be cautious of that. So, here’s what I need you to understand. Exoomes don’t force healing. They remind the body how healing works. Dr. Deb Muth 19:24They’re not replacing damaged cells. They’re re-educating the cells you already have. They’re turning back time on the biological programs that got turned off by inflammation, toxicity, trauma, time, and chronic disease. Your body knows how to heal. It’s done its entire life. Every cut that closed, every bone that mended, every infection you fought off, your body orchestrated that healing. Dr. Deb Muth 19:51The problem is that chronic disease, chronic inflammation, toxic exposures, poor nutrition, stress, all of these things disrupt the communication networks that coordinate healing. And exoomes restore that communication. They’re like rebooting a computer that’s frozen. They reset the system and remind it how it’s supposed to function. All right. Dr. Deb Muth 20:14So, this would not be complete if we didn’t talk about regulation because this is where a lot of confusion exists. And I want you to be given a real picture. Not fear-mongering, not pretending. There aren’t regulatory considerations, but the actual practical reality of how regenerative medicine is practiced in the United States today. Dr. Deb Muth 20:38Here’s what you need to understand. The FDA regulates these therapies and they have specific frameworks, but there’s important nuances between regulatory text enforcement priorities and actual clinical practice. And there are also state level regulations that provide additional pathways. The FDA regulates human cells, tissues, and cellular and tissue based products. Dr. Deb Muth 21:05We call them HCT/PPS under two main pathways. Section 361 products are those that meet specific criteria. They’re minimally manipulated, intended for homologous use, meaning these tissues perform the same basic function in the recipient as it did in the donor. They’re not combined with non-tissue components and they’re either autotogus, meaning they come from your own tissue, or they have had minimal systemic effect. Dr. Deb Muth 21:38An example of a clear 361 procedure, your doctor harvests your own bone marrow, we call this PRP, performs minimally processing to or uh perform Yeah. performs minimal processing to concentrate the stem cells through a centriuge and injects it into your arthritic knee the same day. That’s autogus same day but minimally manipulated. Dr. Deb Muth 22:04This is unquestionably legal and is being done in regenerative medicine clinics across the country every single day. So there’s section 351 where products are those that don’t meet all the section 361 criteria. They’re classified as drugs or biologic products and they require FDA approval through clinical trials. Dr. Deb Muth 22:27Now here’s where this gets more nuanced. There are regenerative medicine clinics across the United States using stem cell and exoome therapies in different contexts. First FDA registered clinical trials. These are formal research studies with investigational new drug applications. Patients enroll in trials. They sign informed consents. Dr. Deb Muth 22:48They receive therapies as part of their structured research protocols. And this is completely legal and represents the gold standard for gathering evidence. Second is observational studies and registry programs. Many clinics are collecting systemic data on patient outcomes using these therapies even outside the FDA trials. Dr. Deb Muth 23:12They’re documenting results, tracking safety, and contributing to the growing body of clinical evidence. Third, there’s clinical practice under physician discretion. There are physicians using these therapies based on their own clinical judgment informed consent from patients and their interpretation of the regulatory framework particularly around minimal manipulation and homologous use. Dr. Deb Muth 23:34Now there are also state regulations that provide additional legal frameworks. So, for example, Florida has enacted the Right to Try Act and specific regenerative medicine legislation that allows physicians to offer certain stem cell therapies under the state oversight. Utah has passed similar legislation creating pathways for regenerative medicine products. Dr. Deb Muth 23:57And these state laws recognize that patients should have access to potentially beneficial therapies, particularly when used by trained physicians with appropriate informed consent. The regulatory question often centers around are these products minimally manipulated. Some products clearly are not. They’ve been cultured. Dr. Deb Muth 24:20They’ve been expanded in laboratories and those require FDA approval that they don’t have. The FDA has appropriately shut down clinics using those products. But there are other products that undergo processing that many physicians and manufacturers argue constitutes minimal manipulation. And these tissues are cleared, potentially fragmented or particulated to make them more suitable for injection, preserved using methods like cryopreservation or liophalization and packaged. Dr. Deb Muth 24:54But the cells are not cultured or expanded in the laboratory. The FDA has issued guidance suggesting that many of these processing steps constitute more than manipul minimal manipulation. But many physicians, particularly those who specialized in regenerative medicine for years, disagree with that interpretation and they believe that the processing qualifies as minimal manipulation and that the product should fall under section 361 when used for homologous purposes. Dr. Deb Muth 25:24Is there regulatory debate? Absolutely. The FDA and some clinicians have different interpretations of what constitutes minimal manipulation. But here’s the practical reality. There are hundreds of well-trained, bore certified physicians across the United States offering these therapies every single day. Dr. Deb Muth 25:42They’re doing so based on their understanding of the regulations, their clinical experience, their commitment to patient safety, and their belief that these therapies can help people who have exhausted conventional options. The FDA’s enforcement priorities have focused primarily on the most problematic cases. Clin clinics making blatant disease cure claims, products with documented safety issues, clear cases of cellular expansion and culture, or clinics operating with no medical oversight. Dr. Deb Muth 26:15Reputable regenerative medicine physicians are using products from companies that provide comprehensive documentation of their processing methods. third-party sterility testing, certificates of analysis showing bioactive content, and quality control measures that meet or exceed industry standards. Now, let me be very clear about something. Dr. Deb Muth 26:36Quality matters enormously. Not all stem cells and exoome products are created equal. Research by Burger and colleagues published in the Orthopedic Journal of Sports Medicine in 2021 analyzed 12 commercially available stem cell products and found that many contained zero viable cells, high levels of bacteria, endotoxins and inconsistent growth factor concentrations. Dr. Deb Muth 27:01This is why the company providing these biologic matters tremendously. You want products from manufacturers who provide transport documentation in sourcing and processing. Conduct third-party testing and sterility and potency. Offer certificates of analysis for each batch. Use standardized validated processing protocols. Dr. Deb Muth 27:24Have quality control measures that ensure consistency and don’t make outrageous cure claims or promise. The best regenerative medicine physician carefully vet their suppliers. They don’t use products from companies making unrealistic promises. They use products from manufacturers who are transparent, scientifically rigorous, and committed to quality. Dr. Deb Muth 27:46Now, you specifically ask about homologous use and collagen defects. So, let me address this directly for you. Under the FDA guidance, homologous use means the tissue performs the same basic function in the recipient as in the donor. So for connective tissue, tendons, ligaments, cartilage, fascia, all of that which are collagenrich structures using MSC’s or their derivatives could be considered homologous use. Dr. Deb Muth 28:17MSC’s in their native environment provide structural support to produce extracellular matrix including collagen. Using them to support healing in damaged collagen rich tissues like arthritic joints, torn tendons or degenerative ligaments is arguably the same basic function. So using exoomes derived from MSC’s to support collagen synthesis reduce inflammation and promote tissue healing in the same structures. Dr. Deb Muth 28:46Many practitioners argue this also qualifies as homologous use because you’re supporting the structure and function that MSC’s would naturally support. So here’s the bottom line on the regulatory reality. Regenerative medicine is available in the United States. It’s being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 29:11Some therapies are offered in FDA registered clinics and some are offered in observational studies. Some are offered in clinical practice under physician discretion, informed consent, and careful attention to safety. The regulatory landscape is evolving. There are ongoing discussions both federally and state levels about creating clearer pathways for these therapies. Dr. Deb Muth 29:32So, if you choose to go down this road, you want to work with physicians who understand the regulations, who use quality products from reputable manufacturers with rigorous testing and documentation, who are transparent about what they’re using and why, who discuss the current regulatory landscape honestly with you, and who prioritize your safety and truly informed consent above all else. Dr. Deb Muth 29:55This is not a lawless wild wild west. But it is also not as simple as everything is legal and unavailable. It’s a nuanced landscape that requires ethical knowledge. And these practitioners that have this knowledge have got to provide informed patients who understand both the potential benefits and the current regulatory context. Dr. Deb Muth 30:17So let’s have some fun here. Let’s talk about what really matters to you that are listening and that’s what conditions are being supported with these therapies. What does the research show and what are clinicians seeing in actual practice with patients? Because here’s what’s really important. We have both published research evidence and extensive clinical experience. Dr. Deb Muth 30:38And when the two align, that’s when we can feel confident and comfortable about using these approaches. So, let’s start where we have the most substantial evidence. joint health and muscularkeeletal conditions. For arthritis, we have good data. A systemic review by Tan and colleagues published in arthritis research and therapy in 2021 analyzed 20 randomized controlled trials in MSC therapy for knee osteoarthritis. Dr. Deb Muth 31:05They found significant improvements in pain and function particularly in mild to moderate disease. What’s really interesting is when researchers start analyzing whether it was the cells themselves or their secreted factors doing the work. They found that exoomeenriched preparations showed similar benefits to whole cell therapy. Dr. Deb Muth 31:26Now towen colleagues in the biioaterials paper from 2017 demonstrated that MSC derived exoomes could promote cartilage matrix synthesize and reduce inflammation markers. The exoomes carried microarnas that told cartilage cells to make more collagen and proteoglycans, the building blocks of healthy cartilage. Dr. Deb Muth 31:49In clinical practice, physicians are seeing patients with knee, hip, shoulder, and spinal arthritis, experiencing reduced pain, improved function, better motility, and in some cases, measurable improvements in their tissue. I want to share a story here with you because back in 2006, my husband was injured at work. Some of you might have heard me tell this story before. Dr. Deb Muth 32:11Um, he broke two discs in his back and underwent surgery very early on when we started using stem cells. They had put cages and plates in and they used MSC’s to put inside the cage to create a hardened bone so that he could have a fusion and hopefully not have any pain. At the time, what the physician didn’t realize or mistakenly did was he did not put any human bone mixed with these dead cadaavver bone MSC’s. Dr. Deb Muth 32:42And so the MSC’s never grew. They didn’t have anything to grow by. So the plates and the screws just kind of went back and forth for six months before he could see another physician that would look at him differently and understand what actually happened. That was very early on. Today we know so much more than we did before. Dr. Deb Muth 33:01Fast forward to 2014 when my husband was having problems and he couldn’t feel his legs, he couldn’t feel his feet. We decided to undergo uh exoo and stem cell therapy again and we saw a physician in Florida who harvested cells from his bone marrow and his blood and his fat and mixed that all together and then put that back into the back. Dr. Deb Muth 33:27and he had tremendous benefit from it. So, I tell this story because I want you to see the trajectory of how long this has been going on that we’ve been using this and we’re learning as we’re going and things are changing rapidly in this in this world. And so, what we know today and what I’m teaching you today may very well change in a month or six months or a year from now, but we have the foundation at least to understand what is helpful, what is not right now. Dr. Deb Muth 33:54But just be aware that if you’re embarking on exoome or stem cell therapy or MSC’s that you understand that this terrain is going to change. So back to my conversation about what other things can we treat? Well, we can treat tendon and ligament injuries, chronic tennis elbow, Achilles tendonopathy, rotator cuff tears, chronic planter fasciitis. Dr. Deb Muth 34:17These were researched by PA and colleagues in the American Journal of Sports Medicine in 2017 and it showed that bone marrow concentrate injections resulted in improved pain and function compared to steroid injections. Now this mechanism appears to be enhanced collagen remodeling and reduced chronic inflammation. Dr. Deb Muth 34:39These are structural collagenrich tissues using MSC’s or their derivatives for structural support which makes biological sense. It’s homologous use. It’s similar. So clinically we’re seeing athletes, active adults and people with chronic pain who failed physically um failed physical therapy, failed conservative treatments finding relief in this functional uh improvement in this functional world that we live in today. Dr. Deb Muth 35:07So, I want to be clear about what we’re doing here for joint and muscularkeeletal issues. We’re not growing completely new cartilage from scratch or severely destroyed joints. We’re not magically regenerating tissues that’s been gone for decades. That’s not possible here. What you’re doing when you’re using MSSE’s and exoomes is supporting the body’s natural ability to repair, reducing inflam inflammation and damage, and we’re driving progressive degeneration uh or we’re stopping the progressive degeneration. By reducing the Dr. Deb Muth 35:41inflammatory damage, we’re stimulating resonant stem cells that have been dormant. We’re improving blood flow and uh uh oxygen to the tissues like cartilage and tendons. and we’re organizing the body to start creating its own quality collagen as it heals. So, it’s a regenerative support, not a tissue replacement. Dr. Deb Muth 36:07But for many people, this support is lifechanging. So, let’s talk about autoimmune disorders now because this is one of the most exciting and unrecognized applications. autoimmune conditions like rheumatoid arthritis, lupus, MS, Crohn’s disease, ulcerative colitis, Hashimoto’s, they all involve the immune system and the immune system is deregulated. Dr. Deb Muth 36:30And so basically your immune system is seeing this tissue as foreign and it’s attacking it. These MSC’s and their exoomes have profound immune modulatory properties. They don’t suppress the immune system like steroids or imunosuppressive drugs. They modulate it helping to restore balance. So for rheumatoid arthritis, research by Weang and colleagues in stem cells translational medicine in 2016 showed that MSC derived exoomes could shift the balance of immune cells, reducing pro-inflammatory TH7 cells that drive joint disruption uh and increase Dr. Deb Muth 37:08regulatory TE-C cells that maintain immune tolerance. So for MS, a clinical trial by Kasus and colleagues published in archives of neurology back in 2010 evaluated autotogus MSC therapy and MS patients and they found evidence of reduced disease activity, improved neurological function and decreased inflammatory uh lesions on MRI scans. Dr. Deb Muth 37:34The proposed mechanism is MSC’s and their exoomes reduce inflammatory cytoine production promote regulatory imu immune populations support remination of damaged nerves that is rebuilding the protective coating around the nerve fibers and it reduces bloodb brain barrier permeability which prevents immune cells from attacking their brain and spinal cord. Dr. Deb Muth 38:02And so for inflammatory bowel disease, the research by Barnholm uh sorry Barnhorn and colleagues in gut in 2020 showed that MS cell MSC derived extracellular vesicles could support mucosal healing and reduce inflammation in the gut lining. They appeared to restore intestinal barrier function, healing that leaky gut and modulating local immune responses. Dr. Deb Muth 38:30So in clinical practice, physicians are seeing patients with autoimmune conditions, experiencing reduced disease flares, decreasing the need for imunosuppressive medications, improving energy and quality of life, and in some cases extending periods of remission. But here’s what I want you to understand. Dr. Deb Muth 38:52When you see these therapies for autoimmune conditions, we are supporting immune regulation and reducing inflammatory damage. We are not treating or curing the disease in a conventional sense. These therapies work best as part of a comprehensive functional medicine approach that also addresses gut health because 70% of your immune system lives in your gut and environmental triggers like mold, heavy metals, chemical toxins that can drive autoimmune responses, chronic infections that can trigger immune disregulation, stress and nervous system imbalance. And Dr. Deb Muth 39:29these nutritional deficiencies are necessary to help improve the immune function. So regenerative therapy without addressing root causes is like bailing water out of your boat without plugging the hole. You might get temporary relief, but the underlying problem still remains. So let’s talk about neurological conditions. Dr. Deb Muth 39:52And this is where the science gets truly fascinating. for traumatic brain injury and concussion. Research by Zang and colleagues in the Journal of Neurot Trauma in 2015 showed that MSC derived exoomes could reduce brain inflammation, promote neuroplasticity, that’s the brain’s ability to rewire itself and improve cognitive outcomes in animal models. Dr. Deb Muth 40:17The exoomes crossed the bloodb brain barrier, delivered neuroprotective proteins and microRNAs. They reduced inflammation, supported mitochondrial function in injured neurons and promoted both new blood vessels from new blood formation and neurogenesis and the birth of new neurons occurred. Neurological recovery requires a multi-systematic approach. Dr. Deb Muth 40:42Exoomes may support neural repair, but they work best combined with hormone optimization, growth hormone, testosterone, thyroid, pregnnolone, mitochondrial support compounds like NAD, CoQ10, PQQ, carnitine, all of those things that we use traditionally in functional medicine. Now for stroke recovery, there was research by Zinn and colleagues in the journal of extracellular vesicles that showed MSC derived exoomes reduced the size of brain damage and improved neurological recovery in animal models. There was a Dr. Deb Muth 41:19Parkinson’s disease study done by Kimoji and colleagues in the movement disorders in 2018 that suggested that MSSE derived exoomes could support dopamineergic neuron survival and those are the cells that die in Parkinson’s and it can help to reduce neuroinflammation. Clinically, physicians are seeing improvements in patients with postconussion syndrome, chronic traumatic brain injury, early stage cognitive decline, and other neurodeenerative conditions. Dr. Deb Muth 41:52These are not cures, but meaningful improvements in cognitive function, mood, energy, and quality of life. Now, let’s talk about autism spectrum disorder very carefully here because this is a very sensitive but very important topic for families. There have been several clinical trials that have explored MSC therapy for autism. Dr. Deb Muth 42:16Liv and colleagues published research in stem cell translational medicine in 2013 showing improvements in social interaction, communication, and behavioral symptoms in children with ASD who received cord blood MSC’s. Dawson and colleagues in 2017 conducted randomized trial autotogus cord blood infusion and found modest improvements in social communication particularly in children with higher baseline immune dysregulation. Dr. Deb Muth 42:47The proposed mechanisms for modulation of neuroinflammation support the mitochondrial function because many children with autism show evidence of mitochondrial dysfunction, reduction of oxidative stress, improvement in gut brain access dysfunction and modulation of immune dysregulation. In clinical practice, some physicians are seeing improvements in some children, better eye contact, increased language development, reduced sensory sensitivities, improved social engagement, but responses vary significantly, and we cannot predict which children will benefit most. So for Dr. Deb Muth 43:26families considering regenerative approaches for autism, these therapies are supporting the body’s healing mechanisms, reducing neuroinflammation, supporting cellular energy production, modulating immune function. These should only be considered as part of a comprehensive biomedical approach that includes dietary interventions to address food sensitivities, support gut health, environmental toxin removal, particularly heavy metals and chemical exposures, gut healing protocols with targeted probiotics and nutrients, Dr. Deb Muth 44:00metabolic testing and targeted supplementation, and evidence-based on behavioral and developmental therapies. These therapies should only be pursued with practitioners who are honest about what we know and what we don’t know and who follow rigorous safety protocols who never promise cures and who view regenerative medicine as a tool in the comprehensive healing strategy, not a standalone miracle. Dr. Deb Muth 44:26Not only that, these therapies will most likely need to be given several times over the course of this person’s lifetime, possibly even on an annual basis. And this is really important because it is not a oneandone. It is not a one-sizefits-all, and it needs to be looked at as a long-term option for working with autism. So, since we’re looking at stem cells versus exoomes, living cells, with stem cell therapy, you’re receiving living cells that can survive in your body for days to weeks. Dr. Deb Muth 45:02With exoome therapy, there are no living cells, just biological messages they would have sent. So, replication stem cells can potentially replicate. Although therapeutically this happens minimally, exoomes cannot replicate. They deliver the cargo and then they are cleared by your body. With stem cells, it’s primarily paracrine signaling. Dr. Deb Muth 45:28They’re coaching your cells to heal. With exoomes, it’s pure signaling, pure reprogramming your cells without any cellular component. Stem cells as we talked about can be autotogus from your own bone fat, blood or um bone marrow or allergenic from umbilical cord tissue or Wharton’s jelly. Dr. Deb Muth 45:50Exoomes are typically derived from cultured MSC’s often from umbilical cord or bone marrow sources and both can be given by local injection for targeted treatment of joints and tissues and exoomes can be given intravenously for whole body systemic support. both have um low immun immunogicity. I can’t say that word today. Dr. Deb Muth 46:17But exoomes have even lower risk since they contain no cellular material. Now, it’s absolutely critical for you to understand that there are massive quality differences. We’ve talked about this earlier. I want you to be very aware of this and have a conversation with any of the practitioners that you’re considering undergoing this treatment with. Dr. Deb Muth 46:37Here is where it matters more than anything when you’re considering regenerative medicine, the quality of the products and the expertise of the practitioner. Because the reality is not all regenerative medicine products are created equal. We all know that when we take different supplements and not all practitioners understand these therapies at the same depth. Dr. Deb Muth 46:58You want to look for practitioners that are board certified or have some kind of specialized regenerative medicine training. You want to know their clinical experience. How much have they done these procedures? How long have they done this? You want honest communication about the evidence and the limitations in this. Dr. Deb Muth 47:17You want a comprehensive functional medicine approach to go along with these therapies. And you want somebody that’s transparent about their informed consent and their regulatory status. If you have people that are uh claiming that they can cure disease or giving you guarantees, that is not that is not a good practitioner to work with. Dr. Deb Muth 47:37If you have high pressure sales tactics, you need to decide today limited supply for a week. These are marketing manipulations. It’s not medical care. You want to be cautious of extremely low prices because quality regenerative products are expensive to source, process, and test. and store. And if somebody’s offering stem cells or exoomes for a few hundred dollars, seriously, you need to question the quality, the safety, and where they got this from. Dr. Deb Muth 48:09So before undergoing any regenerative therapy, make sure you’re having a very, very lengthy conversation with the person and so you truly understand exactly what you’re getting, how it’s going to be delivered, and what they’re going to do. If there’s one thing I want you to take away from today is that your body has remarkable capacity to heal when given the right biological signals and the right environment. Dr. Deb Muth 48:35Stem cells and exoomes are powerful tools for providing biological signaling that can reduce inflammation, modulate immune function, support tissue repair, and restore cellular communication that’s been disrupted by chronic disease and inflammation. These therapies are available in the United States through trained physicians working in FDA registered trials, observational studies, and clinical practice, and using quality products from manufacturers with rigorous testing and quality control. Dr. Deb Muth 49:04So before you invest in regenerative medicine, do your homework. Ask detailed questions about product quality and source. Verify the products come from reputable manufacturers with certificates of analysis, third-party testing. Work with experienced practitioners. And remember, no injection, no infusion, no biologic can overcome ongoing toxic exposure, chronic stress, poor nutrition, gut dysfunction, and inadequate sleep. Dr. Deb Muth 49:34True healing requires your body and you to actively participate in this healing. If you are unwilling to address the root causes and change the lifestyle factors that disrupted your health in the first place, the biologics can amplify your healing signals, but you have to create the internal environment where healing can actually happen. Dr. Deb Muth 49:56So, I hope this episode has helped you understand regenerative medicine more clearly. Share it with somebody who’s looking for healing beyond the conventional approaches. And until next time, this has been Let’s Talk Wellness Now. Have a blessed day. >> Welcome to Let’s Talk Wellness Now, where we bring expert insights directly to you. Dr. Deb Muth 50:16Please note that the views and information shared by our guests are their own and do not necessarily reflect those of Let’s Talk Wellness Now, its management, or our partners. Each affiliate, sponsor, and partner is an independent entity with its own perspectives. Today’s content is provided forformational and educational purposes only and should not be considered specific advice, whether financial, medical, or legal. Dr. Deb Muth 50:41While we strive to present accurate and useful information, we cannot guarantee its completeness or relevance to your unique circumstances. We encourage you to consult with a qualified professional to address your individual needs. Your use of information from this broadcast is entirely at your own risk. Dr. Deb Muth 51:00By continuing to listen, you agree to indemnify and hold Let’s Talk Wellness Now and its associates harmless from any claims or damages arising from the use of this content. We may update this disclaimer at any time, and changes will take effect immediately upon posting or broadcast. Thank you for tuning in. We hope you find this episode both insightful and thought-provoking. Listener discretion is advised.The post Episode 265 – The Future of Healing: How Exosomes Re-Educate Your Body to Heal Itself first appeared on Let's Talk Wellness Now.

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Justice For Some: Law and the Question for Palestine with Noura Erakat (Episode 59)

Play Episode Listen Later May 20, 2026 74:01

How has international law been strategically deployed to shape the Palestinian struggle for freedom across a century-long arc, from the Balfour Declaration in 1917 to present-day wars in Gaza. Join host Sahar Aziz in conversation with Noura Erakat about the promise and risk of international law in the pursuit of Palestinian freedom and the broader relationship between law and liberation. Our discussion examines the concept of "legal work"—the deliberate efforts by powerful actors to bend legal doctrine to their objectives—and how this has transformed international law to advance certain interests over others. We delve into the "sovereign exception" framework that has enabled the creation of exceptional legal categories excluding Palestinians from otherwise applicable protections, from the British Mandate period through Israeli occupation and colonization. Legal strategies have been used to consolidate territorial control, facilitate dispossession, and legitimize military tactics that compromise civilian protections globally, while also exploring moments when weaker actors have leveraged law's emancipatory potential through strategic and tactical ingenuity. Professor Noura Erakat's groundbreaking work demonstrates that the law's current outcomes were never inevitable—that law is politics, and its meaning depends on political intervention by states and people alike. Through original interviews with principals from Israeli-Palestinian negotiations and comprehensive historical analysis, she reveals how Palestinian leaders gained significant legal victories at the UN before eventually exchanging hard-won international recognition for a bilateral peace process that accelerated their dispossession. Her work shows both the profound limitations of international law when serving the powerful and its counterintuitive utility when mobilized in support of political movements seeking liberation. BiographyNoura Erakat is Professor of Africana Studies and Criminal Justice at Rutgers University, New Brunswick. She is the author of Justice for Some: Law and the Question of Palestine (Stanford University Press, 2019), which received the Palestine Book Award and the Bronze Medal for the Independent Publishers Book Award in Current Events/Foreign Affairs. She is a legal scholar with research interests in humanitarian law, human rights law, critical race theory, national security law, and Palestinian Studies. She has published over two dozen academic articles and book chapters, including in the American Journal of International Law, American Quarterly, and the Oxford Bibliographies in International Law. Recommended ReadingNoura Erakat, Justice for Some: Law and the Question of Palestine (Stanford 2019)Rashid Khalidi, The One Hundred Years' War on Palestine (MacMillan 2020)#Israel #Palestine #Gaza #Genocide #ICC #HumanRights #InternationalLawSupport the showSupport the Center for Security, Race and Rights by following us and making a donation:Donate: https://give.rutgersfoundation.org/csrr-support/20046.html Subscribe to our Youtube Channel: https://www.youtube.com/playlist?list=PLEbUfYcWGZapBNYvCObiCpp3qtxgH_jFy Follow us on Twitter: https://twitter.com/rucsrr Follow us on Instagram: https://instagram.com/rutgerscsrr Follow us on Threads: https://threads.com/rutgerscsrr Follow us on Facebook: https://facebook.com/rucsrr Follow us on TikTok: https://tiktok.com/rucsrr

tiktok race war professor security legal rights gaza israelis palestine threads palestinians criminal justice rutgers university new brunswick american journal israeli palestinian international law africana studies bronze medal one hundred years balfour declaration rashid khalidi british mandate american quarterly noura erakat sahar aziz palestine book award

GABA, Sleep, and Brain Health – Neurological Recovery

Recovery After Stroke

Play Episode Listen Later May 19, 2026 9:43

Does GABA Actually Help With Sleep? What the Research Says for Brain Injury Recovery Someone in our community recently asked me about GABA for sleep. They’d seen it recommended online, understood that sleep was critical for their recovery, and wanted to know whether the supplement was worth exploring or just noise. It’s a genuinely good question. And it deserves a proper answer. In this post, I’m going to walk you through what GABA is, what the clinical research actually shows about its effect on sleep, why the blood-brain barrier debate matters (and why it might not derail the whole argument), and what the evidence says about the relationship between sleep and brain recovery. By the end, you’ll have enough to have an informed conversation with your medical team. I’m not a doctor. I’m a three-time haemorrhagic stroke survivor who has spent years researching the science of brain recovery and interviewing hundreds of clinicians and survivors on the Recovery After Stroke podcast. What I offer is a careful read of the evidence, not a clinical prescription. What Is GABA and Why Does It Matter for Sleep? GABA (gamma-aminobutyric acid) is the brain’s primary inhibitory neurotransmitter. If your nervous system were a car, GABA is the brake pedal. It reduces neuronal excitability, quiets cortical arousal, suppresses the brain’s primary arousal centre (the locus coeruleus), and modulates the HPA axis, the stress-response system that drives cortisol. Most sedative medications work by amplifying GABA activity. Benzodiazepines, for instance, bind to GABA-A receptors to increase chloride channel opening, producing their calming effect. GABA isn’t doing something unusual here – it’s doing something fundamental. The question with supplemental oral GABA is more specific: Does taking GABA as a capsule or powder actually produce meaningful neurological effects? What Does the Research Show? Finding 1 — Oral GABA Reduces Sleep Latency (and EEG Can Measure It) A 2015 clinical trial published in the Journal of Nutritional Science and Vitaminology by Yamatsu and colleagues used EEG measurement, actual brainwave monitoring, rather than self-reported sleep questionnaires. One hundred milligrams of oral GABA shortened sleep latency (time to fall asleep) by 5.3 minutes compared to placebo. That might sound modest. But for someone lying awake for 30–40 minutes each night, it’s a meaningful shift. Crucially, this was objective neurophysiological data, not a survey response. (PMID: 26052150) Finding 2 — A 90-Day RCT Showed Improved Sleep Efficiency and Mood A 2024 randomised double-blind placebo-controlled trial published in the Journal of Dietary Supplements (Guimarães et al.) gave 200 mg of GABA daily for 90 days to sedentary overweight women also undergoing an exercise program. The GABA group showed significantly improved Pittsburgh Sleep Quality Index (PSQI) scores, significantly reduced depression scores, and improved heart rate variability, a marker of parasympathetic nervous system activity. The HRV finding is particularly interesting. It suggests GABA may be doing something broader than simply reducing sleep latency – it appears to support the overall physiological state that makes rest restorative. (PMID: 38321713) Finding 3 — But a High-Dose RCT Found No Effect Here’s where intellectual honesty matters. A 2023 Dutch RCT (de Bie et al.) published in the American Journal of Clinical Nutrition gave participants 500 mg of GABA three times daily, 1,500 mg/day total, and found no significant effect on self-reported sleep quality. Fasting plasma GABA wasn’t significantly elevated either, raising real bioavailability questions at that dose. This isn’t a reason to dismiss GABA entirely. It is a reason to pay attention to the dose. The evidence base supports 100–300 mg, not 1,500 mg. Higher is not better, and the non-linear dose response is clinically important. (PMID: 37495019) The Blood-Brain Barrier Debate — and Why the Gut May Be the Point The most common objection to oral GABA supplementation is this: GABA is a zwitterion at physiological pH, meaning it has low lipophilicity and poor predicted ability to cross the blood-brain barrier via passive diffusion. So if it can’t get into the brain directly, how does it produce neurological effects? The emerging explanation involves the gut-brain axis. The enteric nervous system, your gut’s own neural network, has GABA receptors. When oral GABA activates these enteric receptors, it can signal the brain via vagal afferents without needing to cross the BBB at all. Think of it as a side door rather than the front entrance. Supporting this: a 2024 RCT (Li et al.) found that a probiotic strain engineered to increase gut GABA production significantly improved objective sleep duration as measured by wearable devices, alongside reduced cortisol and suppressed HPA axis activity. The mechanism wasn’t direct CNS access – it was gut-brain signalling. (PMID: 39385735) The BBB debate doesn’t negate the clinical effect. It changes how we understand the mechanism. Why Sleep Is Not Optional in Brain Recovery This is the part that I think gets underweighted in recovery conversations — and the research is unambiguous. A 2026 large retrospective cohort study (Muhtar et al., Sleep Medicine) matched over 35,000 stroke patients and found that post-stroke insomnia was associated with a 29% higher risk of post-stroke cognitive impairment and a 30% higher risk of all-cause dementia. The association with Alzheimer’s disease was also significant. (PMID: 41924789) A 2024 observational study from Monash University and Alfred Health (Smith et al.) found that in stroke rehabilitation patients, poor sleep quality was significantly associated with higher fatigue severity and lower salivary BDNF gene expression. BDNF (brain-derived neurotrophic factor) is one of the primary molecular drivers of neuroplasticity. Less BDNF means a less receptive environment for the neurological rewiring that rehab is trying to build. (PMID: 38802847) And then there’s the glymphatic system: the brain’s waste-clearance mechanism that is most active during deep sleep. Poor sleep means reduced clearance of metabolic byproducts, including proteins associated with neurodegeneration. This is not a theoretical risk. It is an active, ongoing process. Sleep is not passive recovery. It is one of the primary mechanisms of recovery. What to Do With This Information Here are three practical steps if you’re exploring GABA for sleep: 1. Measure your sleep baseline first. Use the Pittsburgh Sleep Quality Index (freely available online) before you make any changes. Understanding whether you’re struggling with latency, duration, or quality will determine what you actually need to address. 2. If you trial GABA, choose the right form and dose. Look for PharmaGABA — naturally fermented GABA, derived from Lactobacillus hilgardii, which has the strongest clinical evidence base. A dose of 100–300 mg taken 30–60 minutes before bed is consistent with the positive studies. Avoid very high doses; the null result at 1,500 mg/day is important context. Important drug interaction note: If you are taking benzodiazepines, anticonvulsants (gabapentin, pregabalin, valproate), or any other GABAergic medication, discuss GABA supplementation with your prescriber before adding it. The additive sedative effect is a real risk. The same applies if you drink alcohol regularly. 3. Don’t skip the foundation. Sleep hygiene interventions, consistent sleep and wake times, a dark and cool room, and no screens in the 60 minutes before bed, are consistently among the highest-leverage sleep interventions in the literature. GABA may provide a genuine incremental benefit. But it cannot compensate for a fundamentally disrupted sleep environment. The Bottom Line The evidence for GABA and sleep is more substantive than I expected when I started researching it. The EEG data is real. The 90-day RCT showed meaningful clinical outcomes. The gut-brain axis mechanism is biologically plausible and now has direct RCT support. And the consequences of poor sleep in neurological recovery are not trivial – they are quantifiable, significant, and, to a degree, addressable. GABA is not a guaranteed fix. Individual responses vary. The research is not yet definitive at the level of large multi-centre trials in neurological populations. But as one tool in a comprehensive approach to sleep quality alongside good sleep hygiene, appropriate medical support, and consistent rehabilitation, the case for cautious exploration is reasonable. The next step is a conversation with your neurologist, GP, or rehab physician. Take the research with you if it’s useful. Research References All studies cited in this post are retrievable via PubMed: Yamatsu et al. — GABA sleep latency EEG clinical trial (2015) — PMID: 26052150 Guimarães et al. — GABA 200mg RCT, sleep efficiency + mood (2024) — PMID: 38321713 de Bie et al. — GABA high-dose RCT, null sleep result (2023) — PMID: 37495019 Li et al. — Gut-brain GABA axis and sleep RCT (2024) — PMID: 39385735 Muhtar et al. — Post-stroke insomnia and cognitive decline cohort (2026) — PMID: 41924789 Smith et al. — Sleep, BDNF, and fatigue in stroke rehabilitation (2024) — PMID: 38802847 This post is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before making changes to your supplementation or treatment plan. If you or someone you care about is recovering from a stroke, brain injury, or any neurological condition, the Recovery After Stroke podcast and this blog exist for you. Subscribe on YouTube @BillGasiamis, or visit Recovery After Stroke to find episodes, resources, and community. The post GABA, Sleep, and Brain Health – Neurological Recovery appeared first on Recovery After Stroke.

VOMIT Trial: Mirtazapine vs Ondansetron for HG

PsychEd: educational psychiatry podcast

Play Episode Listen Later May 18, 2026 22:12

Hyperemesis gravidarum (HG) represents the most severe end of the nausea and vomiting of pregnancy spectrum. It has a reported incidence of approximately 0.3–3% of pregnancies and is the most common cause of hospitalization in early pregnancy and the second most common cause of hospitalization in pregnancy overall. In June 2024, the ACOG published a Clinical Expert series summarizing the inpatient management of HG. In that guidance, it describes mirtazapine as an “alternative pharmacologic” option. How effective is this medication compared to ondansetron? A new study (published ahead of print on 12/30/25 and officially out June 2026), out of Denmark, sheds some new light on this medication. This trial is the first double-blind RCT comparing mirtazapine to ondansetron AND placebo. Although a BIG limitation of this study exists (which we will discuss), it does provide some interesting insights. Listen in for details.1. (ACOG CES) Clark, Shannon M. MD; Zhang, Xue MD; Goncharov, Daphne Arena MD. Inpatient Management of Hyperemesis Gravidarum. Obstetrics & Gynecology 143(6):p 745-758, June 2024. | DOI: 10.1097/AOG.00000000000055182. Ostenfeld, AnneDroogh, Marjoes et al.Mirtazapine or ondansetron for hyperemesis gravidarum. A randomized placebo-controlled trial. American Journal of Obstetrics & Gynecology, June 2026

trial denmark zhang american journal obstetrics vomit gynecology doi hg rct acog hyperemesis gravidarum hyperemesis aog ondansetron mirtazapine

How peer pressure built a $5 billion fitness revolution

Nudge

Play Episode Listen Later May 18, 2026 21:55

In Singapore, a group of runners charge 50p per kilometre to run on strangers' Strava accounts. That's how far people will go to look fit online. This episode explains the psychology behind why being watched changes everything. --- Owain's book: https://amzn.to/4smVtrP Owain's company CogCo: https://cogco.co/ Unlock the Nudge Vaults: ⁠https://www.nudgepodcast.com/vaults⁠ Join 11,626 readers of my newsletter: ⁠https://www.nudgepodcast.com/mailing-list ⁠ Connect on LinkedIn: ⁠https://www.linkedin.com/in/phill-agnew/⁠ --- Today's sources: Gerber, A. S., Green, D. P., & Larimer, C. W. (2008). Social pressure and voter turnout: Evidence from a large-scale field experiment. American Political Science Review, 102(1), 33–48. Sallis, A., Harper, H., & Sanders, M. (2018). Effect of persuasive messages on National Health Service organ donor registrations: A pragmatic quasi-randomised controlled trial with one million UK road taxpayers. Trials, 19, 513. Service, O., & Gallagher, R. (2017). Think small: The surprisingly simple ways to reach big goals. Michael O'Mara Books.Triplett, N. (1898). The dynamogenic factors in pacemaking and competition. American Journal of Psychology, 9, 507–533.

PsychEd Shorts 13: Extrapyramidal Symptoms

Play Episode Listen Later May 16, 2026 12:43

Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This short episode covers the basics of extrapyramidal symptoms.Hosts: Jo Kikukawa (MS2)Dr. Matthew Cho (PGY1)Sena Gok (Scientist) Audio Editing: Dr. Matthew Cho (PGY1)References:Dayalu, P., & Chou, K. L. (2008). Antipsychotic-induced extrapyramidal symptoms and their management. Expert Opinion on Pharmacotherapy, 9(9), 1451–1462. https://doi.org/10.1517/14656566.9.9.1451Drake, R. E., & Ehrlich, J. (1985).Suicide attempts associated with akathisia. American Journal of Psychiatry, 142(4), 499–501. https://doi.org/10.1176/ajp.142.4.499Pringsheim, T., Gardner, D., Addington, D., Martino, D., Morgante, F., Ricciardi, L., Poole, N., Remington, G., Edwards, M., Carson, A., & Barnes, T. R. E. (2018). The assessment and treatment of antipsychotic-induced akathisia. Canadian Journal of Psychiatry, 63(11), 719–729. https://doi.org/10.1177/0706743718760288Poyurovsky, M., Pashinian, A., Weizman, R., Fuchs, C., & Weizman, A. (2006). Low-dose mirtazapine: A new option in the treatment of antipsychotic-induced akathisia. A randomized, double-blind, placebo- and propranolol-controlled trial. Biological Psychiatry, 59(11), 1071–1077. https://doi.org/10.1016/j.biopsych.2005.11.004Links to Scales Featured in Episode:https://simpleandpractical.com/wp-content/uploads/2014/09/Barnes-Akathisia-Rating-Scale-BARS.pdfhttps://www.psychdb.com/_media/meds/antipsychotics/sas_simpson_angus_scale_modified.pdfhttps://www.ohsu.edu/sites/default/files/2019-10/%28AIMS%29%20Abnormal%20Involuntary%20Movement%20Scale.pdfFor more PsychEd, follow us on Instagram (⁠⁠⁠@psyched.podcast⁠⁠⁠), Facebook (⁠⁠⁠PsychEd Podcast⁠⁠⁠), X (⁠⁠⁠@psychedpodcast⁠⁠⁠), and Bluesky (⁠⁠⁠@psychedpodcast.bsky.social‬⁠⁠⁠). You can email us at ⁠⁠⁠psychedpodcast@gmail.com⁠⁠⁠ and visit our website at⁠⁠⁠ psychedpodcast.org⁠⁠⁠.

suicide symptoms edwards barnes blue sky shorts psychiatry gardner ehrlich poole american journal fuchs martino chou psyched expert opinions ricciardi canadian journal pharmacotherapy antipsychotics addington biological psychiatry weizman

The “Half-Cm” Cervical Exam: Is that a thing? (With our PGY1 Guest)

exam accuracy american journal obstetrics gynecology cervical dilation pgy1

Play Episode Listen Later May 15, 2026 11:39

Cervical exams can be tricky for the novice practitioner. Think about this: it's a blind exam, we measure that distance using only two fingers, through a layer of tissue, sometimes with a patient moving up on the bed as we examine. That is the reality of a cervical exam. Intrapartum, some nursing staff and clinicians use qualitative descriptors like "a tight 4" or "a generous 5" to convey nuance. In line with this, some report cervical examinations in “half- centimeters”. This sounds like this: “well, her last cervical exam was 5cm but now she is 5 and a half”. Is that a thing? What does the data say? Listen in for details. 1. Hamilton EF, Zhoroev T, Warrick PA, et al. New Labor Curves of Dilation and Station to Improve the Accuracy of Predicting Labor Progress. American Journal of Obstetrics and Gynecology. 2024. 2. Hanidu A, Kovalenko M, Usman S, et al. Intrapartum Ultrasound for Cervical Dilatation: Inter- And Intra-Observer Agreement. Acta Obstetricia Et Gynecologica Scandinavica. 2024. 3. Abedi, P. (n.d.). Accuracy of ultrasound methods versus other methods for detecting of cervical dilatation during labor, a protocol for systematic review. ECronicon.

The Rhythms of Consciousness: Delta, Theta, Alpha, Beta, and Gamma Part 2

Play Episode Listen Later May 15, 2026 65:24 Transcription Available

If you enjoy this episode, we're sure you will enjoy more content like this on The Occult Rejects. In fact, we have curated playlists on occult topics like grimoires, esoteric concepts and phenomena, occult history, analyzing true crime and cults with an occult lens, Para politics, and occultism in music. Whether you enjoy consuming your content visually or via audio, we've got you covered - and it will always be provided free of charge. So, if you enjoy what we do and want to support our work of providing accessible, free content on various platforms, please consider making a donation to the links provided below. Thank you and enjoy the episode!Links For The Occult Rejectshttps://linktr.ee/theoccultrejectsOccult Research Institutehttps://www.occultresearchinstitute.org/Cash Apphttps://cash.app/$theoccultrejectsVenmo@TheOccultRejectsBuy Me A Coffeebuymeacoffee.com/TheOccultRejectsPatreonhttps://www.patreon.com/TheOccultRejectsFull show-notes bibliographyCore EEG and oscillationsAbubaker, M., & Dankaerts, W. (2021). Working memory and cross-frequency coupling of neuronal oscillations. *Frontiers in Psychology, 12*, 742860.Axmacher, N., Henseler, M. M., Jensen, O., Weinreich, I., Elger, C. E., & Fell, J. (2010). Cross-frequency coupling supports multi-item working memory in the human hippocampus. *Proceedings of the National Academy of Sciences, 107*(7), 3228–3233.Jensen, O., & Mazaheri, A. (2010). Shaping functional architecture by oscillatory alpha activity: Gating by inhibition. *Frontiers in Human Neuroscience, 4*, 186.Rayi, A., et al. (2022). Electroencephalogram. *StatPearls*. StatPearls Publishing.StatPearls / NCBI Bookshelf. (2024). Introduction to electroencephalography (EEG). *NCBI Bookshelf*.Theta, alpha, beta, gamma, and controlCavanagh, J. F., & Shackman, A. J. (2015). Frontal midline theta reflects anxiety and cognitive control: Meta-analytic evidence. *Journal of Physiology-Paris, 109*(1–3), 3–15.Eisma, J., et al. (2021). Frontal midline theta differentiates separate cognitive control strategies while still generalizing the need for cognitive control. *Scientific Reports, 11*, 14641.Jensen, O., Bonnefond, M., & VanRullen, R. (2012). An oscillatory mechanism for prioritizing salient unattended stimuli. *Trends in Cognitive Sciences, 16*(4), 200–206.Lundqvist, M., Herman, P., & Miller, E. K. (2018). Working memory: Delay activity, yes! Persistent activity? Maybe not. *Journal of Neuroscience, 38*(32), 7013–7019.Sleep architecture, spindles, and memoryCaporro, M., Haneef, Z., Yeh, H.-J., Mohamed, F. B., & Levin, H. S. (2012). Functional MRI of sleep spindles and K-complexes. *Clinical Neurophysiology, 123*(2), 303–309.Chen, P., Miao, X., Chen, J., et al. (2023). The devastating effects of sleep deprivation on memory: Lessons from rodent models, aging, and Alzheimer's disease. *Frontiers in Neuroscience, 17*, 1151639.Ng, T., et al. (2025). Bayesian meta-analysis reveals the mechanistic role of slow oscillation-spindle coupling in sleep-dependent memory consolidation. *eLife, 13*, RP101992.Patel, A. K., et al. (2024). Physiology, sleep stages. *StatPearls*. StatPearls Publishing.Páez, A., Gillman, S. O., Dogaheh, S. B., et al. (2025). Sleep spindles and slow oscillations predict cognition and biomarkers of neurodegeneration in mild to moderate Alzheimer's disease. *Alzheimer's & Dementia, 21*, e14424.Hypnagogia, N1, and dream incubationHorowitz, A. H., Esfahany, S., Boyle, M. R., et al. (2023). Targeted dream incubation at sleep onset increases post-sleep creative performance. *Scientific Reports, 13*, 5055.Lacaux, C., Andrillon, T., Bastoul, D., et al. (2021). Sleep onset is a creative sweet spot. *Science Advances, 7*(50), eabj5866.Meditation, prayer, chanting, and yoga nidraDatta, K., Mallick, H. N., Tripathi, M., Ahuja, G. K., & Deepak, K. K. (2022). Electrophysiological evidence of local sleep during yoga nidra practice in young male volunteers. *Frontiers in Neurology, 13*, 910794.Dobrakowski, P., Błaszkiewicz, M., & Skalski, S. (2020). Changes in the electrical activity of the brain in the alpha and theta bands during prayer and meditation. *International Journal of Environmental Research and Public Health, 17*(24), 9567.Gao, J., Leung, H. K., Wu, B. W. Y., Skouras, S., & Sik, H. H. (2019). The neurophysiological correlates of religious chanting. *Scientific Reports, 9*, 4262.Kaur, C., & Singh, P. (2015). EEG derived neuronal dynamics during meditation: Progress and challenges. *Advances in Preventive Medicine, 2015*, 614723.Lomas, T., Ivtzan, I., & Fu, C. H. Y. (2015). A systematic review of the neurophysiology of mindfulness on EEG oscillations. *Neuroscience & Biobehavioral Reviews, 57*, 401–410.Hypnosis and suggestionJensen, M. P., Adachi, T., & Hakimian, S. (2015). Brain oscillations, hypnosis, and hypnotizability. *American Journal of Clinical Hypnosis, 57*(3), 230–253.Kirenskaya, A. V., Novototsky-Vlasov, V. Y., Chistyakov, A. V., & Zvonikov, V. M. (2011). Waking EEG spectral power and coherence differences between highly hypnotizable and low hypnotizable subjects. *International Journal of Clinical and Experimental Hypnosis, 59*(2), 144–164.Mendoza, M. E., & Capafons, A. (2024). Neural correlates of hypnosis: A systematic narrative review. *Frontiers in Psychology, 15*, 1327738.Ritual rhythm, trance, and synchronyHuels, E. R., Kim, H. S., Lee, U., & Mollaahmetoglu, O. M. (2021). Neural correlates of the shamanic state of consciousness. *Frontiers in Human Neuroscience, 15*, 610466.Mogan, R., Fischer, R., & Bulbulia, J. A. (2017). To be in synchrony or not? A meta-analysis of synchrony's effects on behavior, perception, cognition and affect. *Journal of Experimental Social Psychology, 72*, 13–20.Tarr, B., Launay, J., & Dunbar, R. I. M. (2016). Silent disco: Dancing in synchrony leads to elevated pain thresholds and social closeness. *Evolution and Human Behavior, 37*(5), 343–349.Entrainment, binaural beats, fatigue, and overloadGoodman, S. P. J., et al. (2025). Approaches to inducing mental fatigue: A systematic review and meta-analysis of (neuro)physiologic indices. *Neuroscience & Biobehavioral Reviews, 170*, 105957.Ingendoh, R. M., Posny, E. S., & Heine, A. (2023). Binaural beats to entrain the brain? A systematic review of the effects of binaural beat stimulation on brain oscillatory activity, and the implications for psychological research and intervention. *PLOS ONE, 18*(5), e0286023.Snipes, S., et al. (2024). Extended wakefulness alters the relationship between EEG theta and alpha bursts and behavioural outcome. *European Journal of Neuroscience, 60*(8), 6268–6284.Xiang, C., et al. (2024). A resting-state EEG dataset for sleep deprivation. *Scientific Data, 11*, 406.Parkinson's disease and pathological betaAsadi, A., et al. (2022). The origin of abnormal beta oscillations in the parkinsonian corticobasal ganglia circuit. *Frontiers in Neuroscience, 16*, 823719.Paulo, D. L., et al. (2023). Corticostriatal beta oscillation changes associated with cognitive function in Parkinson's disease. *NPJ Parkinson's Disease, 9*, 202.Ancient sleep, dreams, and Asclepian healingAskitopoulou, H. (2015). Sleep and dreams: From myth to medicine in ancient Greece. *Journal of Anesthesia History, 1*(3), 70–75.Kapotsis, G., & Steiropoulos, P. (2025). Sleep incubation [enkoimesis] in medical practice at Asclepieia of Ancient Greece — the Ancient Greek sleep medicine. *Sleep Medicine, 130*, 85–89.Pavli, A. (2024). Asclepieia in ancient Greece: pilgrimage and healing. *Journal of Integrative Medicine and Research, 3*(2), 100119.Also want to remind people about the website, if you're into reading we have tons of information by multiple contributors, and we got t-shirts up on the site if you're interested. Fun fact, the art is all based on the eyeball. A

lessons research meditation sleep cross evolution brain fun psychology progress journal disease dancing greece alzheimer's disease silent delta consciousness ancient public health ritual neuroscience parkinson shaping sciences delay fell clinical approaches dementia chen singh patel hypnosis herman fischer advances rhythms persistent mendoza targeted neurology physiology national academy frontiers levin extended boyle integrative medicine ng international journal wu american journal human behavior gamma dunbar proceedings ancient greece ancient greeks neural eeg kaur deepak government accountability office cognitive science theta sleep medicine leung bayesian preventive medicine european journal plos one binaural frontal snipes lomas tarr heine n1 yeh scientific reports gillman lundqvist ahuja science advances environmental research tripathi elife clinical hypnosis alpha beta xiang entrainment miao experimental social psychology adachi gating launay sik scientific data mogan occult rejects human neuroscience weinreich elger biobehavioral reviews haneef clinical neurophysiology hypnagogia pavli functional mri experimental hypnosis statpearls statpearls publishing eisma theta alpha

The Forgotten Superpower That Every Deeply Connected Person Secretly Uses

Feel Better. Live Free. | Health & Wellness Creating FREEDOM for Busy Women Over 40

Play Episode Listen Later May 14, 2026 25:13

What if the smallest act of vulnerability… could completely change someone's life? In this deeply heartfelt solo episode, Darin explores a simple but radically transformative idea: go first. In a world where people are more digitally connected yet emotionally isolated than ever before, Darin breaks down the neuroscience, psychology, and human power behind making eye contact, giving genuine compliments, expressing appreciation, and risking authentic connection. From oxytocin and nervous system regulation to loneliness research and real-life stories of spontaneous connection with strangers, this episode is a reminder that healing doesn't always begin in a therapist's office—it can begin in a coffee shop, a grocery line, or a brief moment where one human being chooses to truly see another. What You'll Learn Why modern society is experiencing a crisis of disconnection and loneliness The hidden psychological cost of avoiding vulnerability Why brief positive interactions with strangers improve mental health The neuroscience behind social rejection and fear of connection How oxytocin, dopamine, and serotonin are activated through authentic interaction Why vulnerability is a trainable "muscle" that rewires your nervous system The power of eye contact, compliments, and acknowledgment Why meaningful human interaction lowers stress and inflammation How small moments of courage create ripple effects for others Practical ways to "go first" and create more connection every day Chapters 00:00:32 – Sponsor: Fatty15 and the science of cellular health 00:01:03 – C15:0, mitochondrial function, and healthy aging 00:02:12 – Why many people may be deficient in C15 00:03:19 – "Celebrate science": discovering new essential fatty acids 00:04:13 – Opening reflection: noticing strangers in everyday life 00:04:52 – The moment we stop ourselves from speaking 00:05:10 – How many genuine moments do we suppress every day? 00:05:33 – Why these "tiny swallowed moments" matter deeply 00:06:02 – Humanity starving for real human connection 00:06:23 – "I see you. You are real to me." 00:06:51 – Vulnerability begins in ordinary daily moments 00:07:18 – The central thesis: "Go first" 00:07:37 – More surrounded and more isolated than ever before 00:07:57 – Research: meaningful interactions with strangers rarely happen 00:08:07 – Loneliness and lack of belonging in modern society 00:08:27 – Gen Z and Millennials: digitally connected yet emotionally isolated 00:08:47 – The silent routines of everyday life 00:09:16 – Why engaging with strangers feels risky or intrusive 00:09:47 – The cost of avoiding connection 00:10:12 – University of British Columbia study on strangers and belonging 00:10:48 – Positive interactions reducing loneliness and increasing happiness 00:11:03 – People predict interactions will be awkward—and are wrong 00:11:15 – Darin's recent experiments talking to strangers 00:11:38 – "Everyone wants connection" 00:12:00 – The emotional lives strangers are carrying invisibly 00:12:22 – One sentence can remind someone they matter 00:12:38 – Why vulnerability feels biologically terrifying 00:13:05 – Social rejection activating the same pathways as physical pain 00:13:20 – Ancient survival wiring and fear of exclusion 00:13:49 – "Your brain is firing a lion alert" 00:14:05 – What happens biologically when you push through fear 00:14:17 – Dopamine and meaningful social interaction 00:14:53 – Why real connection feels different from notifications 00:14:59 – Oxytocin as an anti-inflammatory bonding hormone 00:15:26 – Genuine interactions changing biology in seconds 00:15:43 – Polyvagal theory and nervous system safety states 00:16:17 – Vulnerability as a practice and a muscle 00:16:37 – Darin's valet story: "Bring the cash back!" 00:17:10 – How small interactions can shift someone's entire day 00:17:20 – Going deeper with loved ones and emotional openness 00:17:53 – Vulnerability rewiring the nervous system 00:18:07 – "If you want love, be love" 00:18:24 – Small acts of kindness shifting your heart and brain 00:18:53 – Sponsor: Shakeology and nutrient density 00:20:40 – Six practical ways to practice vulnerability 00:21:05 – Action #1: make eye contact and say hello 00:21:25 – Stop swallowing genuine compliments 00:21:46 – Asking deeper, more meaningful questions 00:22:05 – Giving honest answers instead of autopilot responses 00:22:28 – Seeing and acknowledging "invisible" people 00:22:50 – Gratitude toward workers, attendants, and strangers 00:23:04 – Reaching out to someone who changed your life 00:23:30 – "Going first" is about willingness, not fearlessness 00:23:59 – Stop hiding behind your phone and look around 00:24:16 – Human connection as medicine and nervous system healing 00:24:35 – Tell someone they made you smile today 00:24:50 – Calling loved ones and expressing appreciation 00:24:59 – "Don't let another moment go by without fully engaging in your life" 00:25:07 – Closing reflections: "This is SuperLife" Thank You to Our Sponsors Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Shakeology: Get 15% off with code DARINO1BODI at Shakeology.com. Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences New Show: Roadmap to Happiness Key Takeaway "Vulnerability isn't weakness, it's willingness. The willingness to go first. To smile first. To speak first. To love first. Because every time you choose connection over fear, you're not only changing someone else's day… you're rewiring your own biology, your nervous system, and your relationship to the world around you." Bibliography/Sources: Public Health & Loneliness Data American Psychological Association. (2023). Stress in America 2023: A nation in crisis. https://www.apa.org/news/press/releases/stress British Red Cross. (2022). Tackling loneliness: From awareness to action. https://www.redcross.org.uk/about-us/what-we-do/action-on-loneliness Cigna. (2023). Cigna U.S. loneliness index. Evernorth Health Services. https://newsroom.cigna.com/loneliness-epidemic-continues-to-rise-cigna-study The Science of Micro-Connections & Strangers Barlow, J., & Møller, C. (1996). A complaint is a gift: Recovering customer loyalty when things go wrong. Berrett-Koehler Publishers. https://www.bkconnection.com/books/title/A-Complaint-Is-a-Gift Epley, N., & Schroeder, J. (2014). Mistakenly seeking solitude. Journal of Experimental Psychology: General, 143(5), 1980–1999. https://doi.org/10.1037/a0037323 Sandstrom, G. M., & Dunn, E. W. (2014a). Is efficiency overrated? Minimal social interactions lead to belonging and positive affect. Social Psychological and Personality Science, 5(4), 437–442. https://doi.org/10.1177/1948550613502990 Sandstrom, G. M., & Dunn, E. W. (2014b). Social interactions and well-being: The surprising power of weak ties. Personality and Social Psychology Bulletin, 40(7), 910–922. https://doi.org/10.1177/0146167214529799 Neuroscience of Social Rejection & Vulnerability Eisenberger, N. I. (2012). The neural bases of social pain: Evidence for shared representations with physical pain. Psychosomatic Medicine, 74(2), 126–135. https://doi.org/10.1097/PSY.0b013e3182464dd1 Eisenberger, N. I., & Lieberman, M. D. (2004). Why rejection hurts: A common neural alarm system for physical and social pain. Trends in Cognitive Sciences, 8(7), 294–300. https://doi.org/10.1016/j.tics.2004.05.010 Gross, J. J., & Levenson, R. W. (1997). Hiding feelings: The acute effects of inhibiting negative and positive emotion. Journal of Abnormal Psychology, 106(1), 95–103. https://doi.org/10.1037/0021-843X.106.1.95 Porges, S. W. (2011). The polyvagal theory: Neurophysiological foundations of emotions, attachment, communication, and self-regulation. W. W. Norton & Company. https://wwnorton.com/books/9780393707007 Gratitude, Disclosure & Emotional Expression Algoe, S. B. (2012). Find, remind, and bind: The functions of gratitude in everyday relationships. Social and Personality Psychology Compass, 6(6), 455–469. https://doi.org/10.1111/j.1751-9004.2012.00439.x Algoe, S. B., Haidt, J., & Gable, S. L. (2008). Beyond reciprocity: Gratitude and relationships in everyday life. Emotion, 8(3), 425–429. https://doi.org/10.1037/1528-3542.8.3.425 Frattaroli, J. (2006). Experimental disclosure and its moderators: A meta-analysis. Psychological Bulletin, 132(6), 823–865. https://doi.org/10.1037/0033-2909.132.6.823 Pennebaker, J. W. (1997). Writing about emotional experiences as a therapeutic process. Psychological Science, 8(3), 162–166. https://doi.org/10.1111/j.1467-9280.1997.tb00403.x Seligman, M. E. P., Steen, T. A., Park, N., & Peterson, C. (2005). Positive psychology progress: Empirical validation of interventions. American Psychologist, 60(5), 410–421. https://doi.org/10.1037/0003-066X.60.5.410 Relationship Building, Oxytocin & Health Aron, A., Melinat, E., Aron, E. N., Vallone, R. D., & Bator, R. J. (1997). The experimental generation of interpersonal closeness. Personality and Social Psychology Bulletin, 23(4), 363–377. https://doi.org/10.1177/0146167297234003 Brown, B. (2012). Daring greatly: How the courage to be vulnerable transforms the way we live, love, parent, and lead. Gotham Books / Penguin. https://brenebrown.com/book/daring-greatly/ Canevello, A., & Crocker, J. (2010). Creating good relationships: Responsiveness, relationship quality, and interpersonal goals. Journal of Personality and Social Psychology, 99(1), 78–106. https://doi.org/10.1037/a0018186 Cohen, S., Doyle, W. J., Turner, R. B., Alper, C. M., & Skoner, D. P. (2003). Sociability and susceptibility to the common cold. Psychological Science, 14(5), 389–395. https://doi.org/10.1111/1467-9280.01452 Szeto, A., Sun-Suslow, N., Mendez, A. J., Hernandez, R. I., Wagner, K. V., & McCabe, P. M. (2017). Regulation of the macrophage oxytocin receptor in response to inflammation. American Journal of Physiology—Endocrinology and Metabolism, 312(2), E183–E189. https://doi.org/10.1152/ajpendo.00424.2016 Uvnas-Moberg, K. (2003). The oxytocin factor: Tapping the hormone of calm, love, and healing. Da Capo Press. https://books.google.com/books?id=b-aKjQoB_nQC

america university community science social action giving energy stress research happiness writing gratitude wellness positive celebrate millennials practical park journal humanity human gen z vulnerability reaching loneliness personality forgotten superpowers chapters emotion ancient connected tackling neuroscience hiding british columbia recovering wagner tapping regulation gross peterson genuine ingredients hernandez deeply dunn darin dopamine doyle experimental metabolism minimal daring secretly extended psy mccabe schroeder american journal mendez relationship building oxytocin social psychology steen lieberman cognitive science psychological science crocker starter kits cigna gable empirical responsiveness seligman alper polyvagal mistakenly haidt levenson american psychologist pennebaker bator sandstrom shakeology psychological bulletin british red cross abnormal psychology social psychology bulletin vallone sociability psychosomatic medicine personality science superlife da capo press norton company szeto berrett koehler publishers experimental psychology general physiology endocrinology

Why Every Woman Over 40 Should Know About Creatine

Play Episode Listen Later May 14, 2026 21:17

Episode SummaryWomen have up to 70-80% lower creatine stores than men — and most of us have never been told that. In this episode Lisa digs into what that means for your brain, sleep, mood, muscles, and energy, and why creatine may be one of the most underreported tools in women's health right now.What You'll LearnWhat creatine actually is and why it matters beyond the gymWhy women have lower creatine stores — and why that gap widens in perimenopauseHow creatine supports brain energy (ATP) and what happens when levels run lowThe research on creatine and memory, processing speed, and mental clarityWhy creatine may reduce depression symptoms — more so in women than menCreatine and sleep: the adenosine mechanism, the 2024 women's RCT, and the 2025 perimenopause findingsThe University of Kansas Alzheimer's pilot studyCreatine + resistance training for muscle and bone health over 40How much to take: 5g for general health vs. 10g for brain-specific benefitsStart HereReady to heal your metabolism? thinlicious.com/happyStudies ReferencedCognitive Function & MemoryXu et al. (2024) — Creatine & Cognitive Function: Systematic Review & Meta-Analysis. Frontiers in Nutrition.Depression in WomenLyoo et al. (2012) — Creatine Augmentation for SSRI in Women With Major Depression. American Journal of Psychiatry.Systematic Review & Meta-Analysis: Creatine for Depression (2025). British Journal of Nutrition.SleepDworak et al. (2017) — Creatine Reduces Sleep Need & Homeostatic Sleep Pressure in Rats. Journal of Sleep Research.Aguiar Bonfim Cruz et al. (2024) — Creatine Improves Sleep in Naturally Menstruating Females. Nutrients.Gordji-Nejad et al. (2024) — Single Dose Creatine Improves Cognition During Sleep Deprivation. Scientific Reports.Hall et al. (2025) — Creatine + Resistance Training in Peri/Postmenopausal Women: Sleep, Cognition, Strength. JISSN.Alzheimer's DiseaseSmith et al. (2025) — Creatine Monohydrate Pilot in Alzheimer's: Brain Creatine & Cognition. Alzheimer's & Dementia.Brain Dosing: The Case for 10gDechent et al. (1999) — Creatine Increases Brain Creatine by 8.7% in Human Neuroimaging Study. American Journal of Physiology.Candow et al. — Higher Creatine Doses for Brain Bioenergetics. Journal of Psychiatry and Brain Science.Dr. Rhonda Patrick on 10g brain dosing (@foundmyfitness)Medical Disclaimer: For educational purposes only. Not medical advice. Always consult your doctor before starting any new supplement.

Carrington Event

The Thinking Practitioner

Play Episode Listen Later May 13, 2026 43:31 Transcription Available

The Carrington Event was a massive geomagnetic storm that happened in 1859. It led to expanded understanding of solar phenomena. Research: “Great Aurora of 1859. Art. XLII – The Great Auroral Exhibition of August 28th to September 4th, 1859.” American Journal of Science. Ser. 2. Vol. 28. July-November 1859. Cardenas, Freddy Moreno et al. “The Grand Aurorae Borealis Seen in Colombia in 1859.” Preprint submitted to Advances in Space Research. August 21, 2015. Cliver, E.W. “The 1859 space weather event: Then and now.” Advances in Space Research. 38 (2006) 119-129. Cliver, E.W. and L. Svalgaard. “The 1859 Solar-Terrestrial Disturbance and the Current Limits of Extreme Space Weather Activity.” Solar Physics. (2004) 224: 407–422. Cliver, Edward W. and William F. Dietrich. “The 1859 space weather event revisited: limits of extreme activity.” J. Space Weather Space Clim. 3 (2013) A31 DOI:10.1051/swsc/2013053 Dobrijevic, Daisy and Andrew May. “The Carrington Event: History's greatest solar storm.” Space.com. 5/20/2022. https://www.space.com/the-carrington-event Giegengack, Robert. “The Carrington Coronal Mass Ejection of 1859.” Proceedings of the American Philosophical Society , DECEMBER 2015, Vol. 159, No. 4. Via JSTOR.https://www.jstor.org/stable/26159195 Green, James L, and Scott Boardsen. “Duration and extent of the great auroral storm of 1859.” Advances in space research : the official journal of the Committee on Space Research (COSPAR) vol. 38,2 (2006): 130-135. doi:10.1016/j.asr.2005.08.054 Green, James L. et al. “Eyewitness Reports of the Great Auroral Storm of 1859.” Submitted to Advances in Space Research. NASA Technical Reports Server (NTRS) 20050210157. 8/5/2005. Haeberle, Tom. “The Carrington Affair!” Amateur Astronomers Association Eyepiece. 9/1/2018. https://aaa.org/2018/09/01/the-carrington-affair/ Hayakawa, Hisashi et al. “Temporal and Spatial Evolutions of a Large Sunspot Group and Great Auroral Storms Around the Carrington Event in 1859.” Space Weather. 8/29/2019. https://agupubs.onlinelibrary.wiley.com/doi/full/10.1029/2019SW002269 Hodgson, R. “On a Curious Appearance Seen in the Sun.” Monthly notices of the Royal Astronomical Society vol. 19-20 (1858-1860). https://academic.oup.com/mnras/article/20/1/15/983497 Hodžić, Jasna. “The Carrington Event of 1859 Disrupted Telegraph Lines. A ‘Miyake Event’ Would Be Far Worse.” JSTOR Daily. 9/7/2023. https://daily.jstor.org/the-carrington-event-of-1859-disrupted-telegraph-lines/ Howard, R.A. (2006). A Historical Perspective on Coronal Mass Ejections. In Solar Eruptions and Energetic Particles (eds N. Gopalswamy, R. Mewaldt and J. Torsti). https://doi.org/10.1029/165GM03 Josefowicz, Diane. “The British Magnetic Scheme (1839-1851): People and Institutions.” Victorian Web. https://victorianweb.org/science/geomagnetism/magneticcrusade.html Kaminski, Isabella. “'The fate of nations and the fall of kingdoms': History's epic theories of what causes aurora.” BBC. 11/16/2025. https://www.bbc.com/future/article/20251114-historys-epic-theories-of-what-causes-aurora Kimball, D.S. “A Study of the Aurora of 1859.” Scientific Report No. 6. NSF Grant No. Y/22.6/327. April 1960. Klein, Christopher. “A Perfect Solar Superstorm: The 1859 Carrington Event.” History. 1/29/2025. https://www.history.com/articles/a-perfect-solar-superstorm-the-1859-carrington-event Marinus Anthony van der Sluijs, Hisashi Hayakawa. “A candidate auroral report in the Bamboo Annals, indicating a possible extreme space weather event in the early 10th century BCE.” Advances in Space Research. Volume 72, Issue 12. 2023. https://doi.org/10.1016/j.asr.2022.01.01 Mills, Virginia. “A message from Alexander von Humboldt.” The Royal Society. 9/23/2019. https://royalsociety.org/blog/2019/09/a-message-from-alexander-von-humboldt/ Muller, C. “The Carrington solar flares of 1859: consequences on life.” Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life vol. 44,3 (2014): 185-95. doi:10.1007/s11084-014-9368-3 Phillips, Tony. “A Warning from History: The Carrington Event Was Not Unique.” Space Weather Archive. 9/1/2020. https://spaceweatherarchive.com/2020/08/30/a-warning-from-history-the-carrington-event-was-not-unique/ Phillips, Tony. “Near Miss: The Solar Superstorm of July 2012.” NASA. 12/22/2014. https://science.nasa.gov/science-research/planetary-science/23jul_superstorm/ C. Carrington, Description of a Singular Appearance seen in the Sun on September 1, 1859, Monthly Notices of the Royal Astronomical Society, Volume 20, Issue 1, November 1859, Pages 13–15, https://doi.org/10.1093/mnras/20.1.13 Starmans, Barbara J. “Carrington Solar Flare of 1859.” The Social Historian. 11/27/2016. https://www.thesocialhistorian.com/carrington-solar-flare-of-1859/ Thompson, D. (2009) The Carrington Event and the Electric Telegraph in Victoria in Museums Victoria Collections https://collections.museumsvictoria.com.au/articles/2880 See omnystudio.com/listener for privacy information.

history art science space research green study bbc nasa sun colombia origins origin thompson vol committee phillips klein pages mills advances institutions muller royal society temporal international society bce american journal proceedings humboldt submitted carrington kimball cardenas kaminski historical perspective hod james l space weather royal astronomical society american philosophical society jasna carrington event space research barbara j coronal mass ejections hayakawa edward w andrew may hisashi solar physics

170: Hypermobile Ehlers-Danlos, Fascia, and Pain (with Tina Wang) Listener Favorite

Play Episode Listen Later May 13, 2026 54:48

books pain academy adhd wang lithuania american journal ultrasounds eds fascia ehlers danlos interoception stiffness medical genetics hypermobile delineation tina j hypermobile ehlers danlos syndrome

BOGO! (With Hanna, PGY1)

Play Episode Listen Later May 12, 2026 13:52

As I have said many times before, some podcast ideas come from REAL clinic encounters. In this episode, Dr Hanna V, our dedicated PGY1 on our call team, and I will answer TWO real questions which arose just today on morning rounds, on our service: 1. Does NORMOTENSIVE HELLP still need Mag Sulfate? And 2. Does an indwelling foley s/p iatrogenic bladder injury at CS require prophylactic antibiotic coverage for urinary infection? Yep: It's a BOGO sale on today's podcast- Buy ONE GET ONE! Listen in for details.1. Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222.Obstetrics and Gynecology. 2020. Committee on Practice Bulletins—ObstetricsGuideline2. Woudstra DM, Chandra S, Hofmeyr GJ, Dowswell T.SR. Corticosteroids for HELLP (Hemolysis, Elevated Liver Enzymes, Low Platelets) Syndrome in Pregnancy.The Cochrane Database of Systematic Reviews. 2010. 3. Joshi D, James A, Quaglia A, Westbrook RH, Heneghan MA.Liver Disease in Pregnancy. Lancet. 2010. Review4. Rimaitis K, Grauslyte L, Zavackiene A, et al.Observational. Diagnosis of HELLP Syndrome: A 10-Year Survey in a Perinatology Centre. International Journal of Environmental Research and Public Health. 20195. Reau N, Munoz SJ, Schiano T.Guideline Liver Disease During Pregnancy.The American Journal of Gastroenterology. 2022. 6. ACG Clinical Guideline: Liver Disease and Pregnancy.The American Journal of Gastroenterology. 2016. Tran TT, Ahn J, Reau NS.7. ACOG Practice Bulletin No. 195: Prevention of Infection After Gynecologic Procedures. Obstetrics and Gynecology. 2018. Committee on Practice Bulletins—Gynecology Guideline8. Niels Johnsen, Hunter Wessells, Krystal Archer-Arroyo, et al. Best Practices Guidelines Management of Gentiunrinary Injuries.American College of Surgeons (2025). 20259. Fletke KJ, Jeong DH, Herrera AV . Urinary Catheter Management. American Family Physician. 2024..

Hantavirus & Preganncy FAQ

united states americans journal south korea emergency medicine american journal obstetrics gynecology hantavirus four corners sparse

Play Episode Listen Later May 11, 2026 16:33

Hantavirus was first discovered in the early 1950s near the Hantaan River in South Korea. The US has seen this before: the 1993 Four Corners outbreak was the first recognition of the virus in the United States, causing a deadly respiratory syndrome. Now, Hantavirus is in the news again with 17 Americans currently (5.10.26) enroute back to the US for specialized observation. In this episode, we will briefly review what this virus does and cover the SPARSE data we have regarding hantavirus infection in pregnancy. 1. Gilson GJ, Maciulla JA, Nevils BG, et al. Hantavirus Pulmonary Syndrome Complicating Pregnancy. American Journal of Obstetrics and Gynecology. 1994. 2. 5.10.26: https://www.nbcnews.com/health/health-news/hantavirus-stricken-cruise-ship-arrives-tenerife-rcna3443183. Janwadkar RS, Ritchie HM, Johnson CA. Unexpected Challenges: A Case Report of Hantavirus Infection in a Pregnant Patient in a Rural Emergency Department. The Journal of Emergency Medicine. 2025.

215. Bilingual Spanish Speech Assessment for $0: The 8-Step Gold Standard Every SLP Needs

The Preschool SLP

Play Episode Listen Later May 10, 2026 19:11

Have zero dollars in your therapy closet for bilingual Spanish assessments? You are not alone — and you are not stuck. In this episode, I walk you through the 8-step gold-standard process for assessing bilingual Spanish-English preschoolers for speech sound disorders, every single step backed by free, vetted, research-supported tools. This is the same framework recommended by Sharynne McLeod, Sarah Verdon, and the International Expert Panel on Multilingual Children's Speech (McLeod, Verdon, & IEPMCS, 2017, AJSLP) — taught to you in plain English with direct links you can click today. You'll learn how to: Capture a true language profile Sample BOTH languages without overdiagnosing dialect features Use narrow IPA transcription so you don't mislabel allophones as errors Distinguish a transfer error from a true speech sound disorder Free Resources Mentioned Step 1 — Language Profile Alberta Language Environment Questionnaire (ALEQ/ALDeQ) + Intelligibility in Context Scale: https://www.ualberta.ca/en/linguistics/cheslcentre/questionnaires.html Intelligibility in Context Scale: https://www.csu.edu.au/research/multilingual-speech/speech-assessments/ics Step 2 — Sampling Both Languages UBC Cross-Linguistic Phonological Development Project (single-word probes in many languages): https://phonodevelopment.sites.olt.ubc.ca/ Frog, Where Are You: https://www.iifilologicas.unam.mx/uploads/IL-2-Lecturas/050-Frog_Story_all_as_pdf_image_300.pdf Step 3 — Narrow IPA Transcription ASHA Spanish Phonemic Inventory: https://www.asha.org/siteassets/uploadedfiles/spanish-phonemic-inventory.pdf Step 4 — Parent Baseline Recording Speech Accent Archive (cross-dialect reference recordings): https://accent.gmu.edu/ Step 5 — Independent Then Relational Analysis Phon software (open-source phonological analysis): https://www.phon.ca/ Step 6 — Rule Out Transfer & Dialect Bilinguistics Spanish-English Articulation Norms Chart: https://bilinguistics.com/articulation-norms-for-spanish-and-english/ Step 7 — Diagnose Only If Errors Appear in BOTH Languages Goldstein & Fabiano (2007) ASHA Leader: https://leader.pubs.asha.org/doi/10.1044/leader.FTR2.12022007.6 Step 8 — Treat with Complex Targets UBC Fun-ology Activities: https://phonodevelopment.sites.olt.ubc.ca/activities-2/activities/ Reference: McLeod, S., Verdon, S., & International Expert Panel on Multilingual Children's Speech (2017). Tutorial: Speech assessment for multilingual children who do not speak the same language(s) as the speech-language pathologist. American Journal of Speech-Language Pathology, 26(3), 691–708. Ready to Optimize Change with Complex Targets? Join the SIS (Speech It Smarter) Membership to learn how to select, sequence, and track complex treatment targets — including three-element /s/ clusters, /fr/ and /fl/ clusters. Join the SIS Membership: https://www.kellyvess.com/sis

english spanish treat speech frogs activities capture ipa bilingual gold standard american journal distinguish fabiano lecturas speech language pathology spanish english verdon intelligibility ajslp

The Rhythms of Consciousness: Delta, Theta, Alpha, Beta, and Gamma

Play Episode Listen Later May 8, 2026 65:07 Transcription Available

healing research sleep brain fun medicine journal disease alzheimer's disease delta consciousness dementia patel hypnosis rhythms neurology physiology frontiers mild integrative medicine ng american journal gamma ancient greece horowitz biomarkers plos one systematic review binaural beats inhibition scientific reports cavanagh pnas datta science advances neurodegeneration elife clinical hypnosis alpha beta entrain occult rejects human neuroscience clinical neurophysiology pavli functional mri theta alpha

The Loneliness Epidemic Is Worse Than We Thought

Stand Up! with Pete Dominick

Play Episode Listen Later May 7, 2026 26:24

What if loneliness isn't just an emotion… but one of the most dangerous biological threats to your health? In this deeply personal and scientifically explosive solo episode, Darin opens up about something he recently realized in his own life: despite being surrounded by people, he was lonely. But what began as an emotional realization quickly became a deep dive into some of the most shocking research he's ever uncovered, showing that chronic loneliness may increase the risk of heart disease, dementia, cancer, autoimmune dysfunction, accelerated aging, and early death. From inflammatory gene expression and cortisol dysregulation to oxytocin, vulnerability, and the collapse of real human connection in the digital age, this episode reveals why loneliness may be the most overlooked "fatal convenience" of modern life, and how vulnerability may be the medicine. What You'll Learn Why loneliness is a biological crisis, not just an emotional feeling The shocking link between loneliness and heart disease, dementia, and early death Why the quality of your relationships is the #1 predictor of long-term health How loneliness activates inflammatory genes inside your body The role of cortisol, sleep disruption, and chronic stress in social isolation Why social media and "surface-level connection" are replacing real intimacy The connection between loneliness and Alzheimer's disease How oxytocin and genuine connection reduce inflammation Why vulnerability is the gateway to meaningful relationships Practical ways to create deeper connection starting today Chapters 00:00:33 – Sponsor: the truth about the exploding NAD supplement market 00:01:04 – Why supplement verification and transparency matter 00:02:17 – Opening: Darin admits something deeply personal 00:02:30 – "I realized recently… I'm lonely" 00:02:37 – The difference between being surrounded by people vs being truly known 00:03:06 – Loneliness as a biological experience, not just an emotional one 00:03:27 – The hidden risks: heart disease, dementia, cancer, early death 00:03:45 – Why this is not fringe science 00:04:13 – The most important predictor of long-term health 00:04:34 – Why relationship QUALITY matters more than quantity 00:05:06 – The global loneliness epidemic 00:05:11 – U.S. Surgeon General advisory on loneliness 00:05:39 – Loneliness declared a public health crisis 00:06:02 – 50% of Americans report measurable loneliness 00:06:22 – "A generational collapse of connection" 00:06:30 – 29% of adults have no close friends 00:06:40 – Face-to-face interactions dramatically declining 00:07:01 – The UK, Japan, and Australia loneliness crisis initiatives 00:07:32 – The paradox: hyperconnected but deeply isolated 00:08:04 – Loneliness as a biological alarm signal 00:08:31 – What loneliness actually looks like in modern life 00:08:42 – The lonely CEO, the unseen mother, the isolated social media addict 00:09:31 – "Perceived social isolation" and why the brain can't tell the difference 00:10:21 – Meta-analysis of 3.4 million people 00:10:55 – Loneliness vs obesity and smoking risk comparisons 00:11:18 – The biology of loneliness begins 00:11:50 – NF-kB: inflammatory gene activation explained 00:12:33 – How loneliness changes gene expression 00:13:02 – Chronic inflammation and disease pathways 00:13:21 – Cortisol, sleep disruption, and immune dysfunction 00:14:00 – How loneliness affects brain repair and amyloid plaque clearing 00:14:21 – Sponsor: Fatty15 and cellular health 00:18:02 – The Alzheimer's and dementia connection 00:18:25 – Loneliness as a major modifiable dementia risk factor 00:18:57 – Cortisol, neuroinflammation, and brain degeneration 00:19:16 – The hippocampus physically shrinking in lonely people 00:19:27 – Social media as a "fatal convenience" 00:19:57 – The oxytocin economy: connection as medicine 00:20:15 – Oxytocin as one of the body's strongest anti-inflammatory molecules 00:20:30 – HeartMath research: emotional synchronization between people 00:20:48 – "You regulate each other's biology" 00:21:07 – The real barrier: vulnerability 00:21:32 – Darin's recent experiences with radical vulnerability 00:21:54 – Conversations with family, ex-partners, and loved ones 00:22:35 – Brené Brown's research on connection and worthiness 00:23:14 – The "depth audit" exercise 00:23:42 – Reaching out, expressing appreciation, and owning your emotions 00:24:01 – Sacred hours: spending time without phones 00:24:13 – Questions that create real intimacy 00:24:30 – Darin's emotional conversation with his brother 00:25:03 – Protecting yourself from social media disconnection 00:25:20 – Becoming a source of joy and connection in everyday life 00:25:25 – Darin reflects on seven years of subtle loneliness 00:25:48 – The shift from surface conversations to meaningful connection 00:26:01 – "If you want love, give love" 00:26:19 – Final message: generate the connection you want to receive 00:26:22 – Closing thoughts and outro Thank You to Our Sponsors Truniagen: Go to www.truniagen.com and use code DARIN20 at checkout for 20% off Fatty15: Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/DARIN and using code DARIN at checkout. Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness Key Takeaway "Loneliness isn't weakness. It isn't failure. It's a biological signal telling you that something essential is missing. And in a world addicted to surface-level connection, the real medicine may simply be this: vulnerability, presence, eye contact, honesty, and the courage to let yourself truly be seen." Bibliography/Sources The Loneliness Epidemic & Public Health Data Bureau of Labor Statistics. (2023). American time use survey. U.S. Department of Labor. https://www.bls.gov/tus/ Cigna. (2023). Cigna U.S. loneliness index. Evernorth Health Services. https://newsroom.cigna.com/loneliness-epidemic-continues-to-rise-cigna-study Murthy, V. H. (2023). Our epidemic of loneliness and isolation: The U.S. Surgeon General's advisory on the healing effects of social connection and community. U.S. Department of Health and Human Services. https://www.hhs.gov/sites/default/files/surgeon-general-social-connection-advisory.pdf Survey Center on American Life. (2021). The state of American friendship: Change, challenges, and loss. American Enterprise Institute. https://www.americansurveycenter.org/research/the-state-of-american-friendship-change-challenges-and-loss/ Mortality & Systemic Health Risk Cohen, S., Doyle, W. J., Skoner, D. P., Rabin, B. S., & Gwaltney, J. M. (1997). Social ties and susceptibility to the common cold. JAMA, 277(24), 1940–1944. https://pubmed.ncbi.nlm.nih.gov/9200634/ Hawkley, L. C., & Cacioppo, J. T. (2010). Loneliness matters: A theoretical and empirical review of consequences and mechanisms. Annals of Behavioral Medicine, 40(2), 218–227. https://pubmed.ncbi.nlm.nih.gov/20396846/ Holt-Lunstad, J., Smith, T. B., Baker, M., Harris, T., & Stephenson, D. (2015). Loneliness and social isolation as risk factors for mortality: A meta-analytic review. Perspectives on Psychological Science, 10(2), 227–237. https://doi.org/10.1177/1745691614568352 Valtorta, N. K., Kanaan, M., Gilbody, S., Ronzi, S., & Hanratty, B. (2016). Loneliness and social isolation as risk factors for coronary heart disease and stroke. Heart, 102(13), 1009–1016. https://heart.bmj.com/content/102/13/1009 Genetics, Inflammation & The Immune System Cole, S. W. (2013). Social regulation of human gene expression: Mechanisms and implications for public health. American Journal of Public Health, 103(S1), S84–S92. https://pmc.ncbi.nlm.nih.gov/articles/PMC3786756/ Cole, S. W., Hawkley, L. C., Arevalo, J. M. G., Sung, C. Y., Rose, R. M., & Cacioppo, J. T. (2007). Social regulation of gene expression in human leukocytes. Genome Biology, 8(9), Article R189. https://pmc.ncbi.nlm.nih.gov/articles/PMC2375027/ Sleep & Cognitive Decline Cacioppo, J. T., Hawkley, L. C., Berntson, G. G., Ernst, J. M., Gibbs, A. C., Stickgold, R., & Hobson, J. A. (2002). Do lonely days invade the nights? Potential social modulation of sleep efficiency. Psychological Science, 13(4), 384–387. https://pubmed.ncbi.nlm.nih.gov/12137144/ Holwerda, T. J., Deeg, D. J. H., Beekman, A. T. F., et al. (2014). Feelings of loneliness, but not social isolation, predict dementia onset. Journal of Neurology, Neurosurgery & Psychiatry, 85(2), 135–142. https://jnnp.bmj.com/content/85/2/135 Oxytocin & The Biology of Connection Szeto, A., Sun-Suslow, N., Mendez, A. J., Hernandez, R. I., Wagner, K. V., & McCabe, P. M. (2017). Regulation of the macrophage oxytocin receptor in response to inflammation. American Journal of Physiology—Endocrinology and Metabolism, 312(2), E183–E189. https://journals.physiology.org/doi/full/10.1152/ajpendo.00424.2016 Uvnas-Moberg, K. (2003). The oxytocin factor: Tapping the hormone of calm, love, and healing. Da Capo Press. https://books.google.com/books?id=b-aKjQoB_nQC Psychology, Vulnerability & Relationship Science Aron, A., Melinat, E., Aron, E. N., Vallone, R. D., & Bator, R. J. (1997). The experimental generation of interpersonal closeness. Personality and Social Psychology Bulletin, 23(4), 363–377. https://doi.org/10.1177/0146167297234003 Brown, B. (2010). The gifts of imperfection: Let go of who you think you're supposed to be and embrace who you are. Hazelden Publishing. https://brenebrown.com/book/the-gifts-of-imperfection/ Cacioppo, J. T., & Patrick, W. (2008). Loneliness: Human nature and the need for social connection. W. W. Norton & Company. https://wwnorton.com/books/9780393335286 Dunbar, R. I. M. (2012). Bridging evolutionary approaches to the social brain and social bonding. In F. B. M. de Waal & P. F. Ferrari (Eds.), The primate mind. Harvard University Press. https://www.hup.harvard.edu/books/9780674063104 Dunbar, R. I. M. (2021). Friends: Understanding the power of our most important relationships. Little, Brown and Company. https://www.hachettebookgroup.com/titles/robin-dunbar/friends/9781408711736/ Waldinger, R., & Schulz, M. (2023). The good life: Lessons from the world's longest scientific study on happiness. Simon & Schuster. https://www.simonandschuster.com/books/The-Good-Life/Robert-Waldinger/9781982166694

ceo american community health australia conversations uk social lessons japan energy change americans heart wellness practical journal harris feelings protecting labor alzheimer's disease worse reaching loneliness personality perspectives chapters sacred public health wagner tapping bridging epidemics regulation chronic ingredients genetics ernst hernandez darin human services sung doyle metabolism neurology bren brown gibbs cortisol extended nad mccabe jama surgeon general schulz inf stephenson american journal mendez mechanisms dunbar perceived s1 oxytocin labor statistics american enterprise institute annals hobson psychological science heartmath american life simon schuster starter kits cigna rabin harvard university press murthy behavioral medicine kanaan arevalo beekman bator waldinger social psychology bulletin cacioppo vallone deeg da capo press norton company nf kb gwaltney survey center genome biology hawkley physiology endocrinology

Dr Miranda Yaver on Health Care + news & Clips

Play Episode Listen Later May 6, 2026 75:34

My conversation with Miranda starts at about 35 minutes Subscribe and Watch Interviews LIVE : On YOUTUBE.com/StandUpWithPete ON SubstackStandUpWithPete Stand Up is a daily podcast. I book,host,edit, post and promote new episodes with brilliant guests every day. This show is Ad free and fully supported by listeners like you! Please subscribe now for as little as 5$ and gain access to a community of over 750 awesome, curious, kind, funny, brilliant, generous souls Miranda Yaver teaches courses on health policy and health politics. She is a political scientist whose research lies at the intersection of health politics, inequality, and administrative burden in U.S. health insurance, with additional projects examining the politics of U.S. health reform as well as ways that patient administrative burden intersects with reproductive health. In addition to her academic appointment, she is co-leader of the Central Pennsylvania Chapter of the Scholars Strategy Network, which connects scholars, journalists, and policymakers to translate academic findings into public facing work that tackles public policy challenges and promotes democracy. She is the 2025 Author-in-Residence in Healthcare Fellow at the Roosevelt Institute. Her research has appeared in the American Journal of Political Science, Journal of Law, Economics and Organization, Scientific Reports, World Medical & Health Policy Journal, and the Journal of Health Politics, Policy, and Law, with additional health politics writings in such outlets as The New York Times, The Washington Post, The Guardian, STATNews, and The Hill. Her forthcoming book, Coverage Denied: How Health Insurers Drive Inequality in the United States, will be published by Cambridge University Press in spring 2026. She was previously an assistant professor of political science at Wheaton College in MA. Listen rate and review on Apple Podcasts Listen rate and review on Spotify Pete On Instagram Pete on Blue Sky Pete on Threads Pete on Tik Tok Pete on Twitter Pete Personal FB page Stand Up with Pete FB page Gift a Subscription https://www.patreon.com/PeteDominick/gift Send Pete $ Directly on Venmo All things Jon Carroll Buy Ava's Art Subscribe to Piano Tuner Paul Paul Wesley on Substack Listen to Barry and Abigail Hummel Podcast Listen to Matty C Podcast and Substack Follow and Support Pete Coe Hire DJ Monzyk to build your website or help you with Marketing

What science has to say about your sweet tooth

The Nutrition Diva's Quick and Dirty Tips for Eating Well and Feeling Fabulous

Play Episode Listen Later May 6, 2026 12:46

862. Can you actually "reset" your taste buds by cutting out sugar? You've heard that a 30-day sugar detox will make your cravings disappear, but a new study in the American Journal of Clinical Nutrition suggests our preference for sweetness is more permanent than we thought. This week, Monica debunks the "palate reset" myth and explores a more effective way to manage a sweet tooth.Key Takeaways:The myth of the palate reset: Why "The Sweet Tooth Trial" found that cutting sugar for 6 months didn't change taste preferences.The first 1,000 days: How early life exposure sets your biological "sweetness" baseline.Behavior over biology: Why addressing emotional triggers is more effective than a 30-day cleanse.Nutrition Diva is a Quick and Dirty Tips podcast, hosted by Monica Reinegal.New to Nutrition Diva? Check out our special Spotify playlist for a collection of the best episodes curated by our team and Monica herself! We've also curated some great playlists on specific episode topics including Staying Strong as We Age, Diabetes, Weight Loss That Lasts and Gut Health! Also, find a playlist of our bone health series, Stronger Bones at Every Age. Have a question for Nutrition Diva? Email: nutrition@quickanddirtytips.comDiscover more from Nutrition Diva:Facebook LinkedInNewsletterTranscripts available at QuickandDirtyTips.com. Hosted on Acast. See acast.com/privacy for more information.

spotify science behavior acast diabetes gut health american journal sweet tooth clinical nutrition staying strong every age dirty tips nutrition diva quickanddirtytips

The 5% Heart Tax: Breaking the Ultra-Processed Food Cycle

Play Episode Listen Later Apr 30, 2026 26:24

What if every time you reached for a packaged snack… you were quietly increasing your risk of a heart attack? In this urgent and deeply personal solo episode, Darin breaks down groundbreaking new research showing that each serving of ultra-processed food may increase cardiovascular risk by over 5%, not over time, but every single time you eat it. This isn't about calories. It's about chemistry, biology, and a system engineered for convenience at the expense of your health. From the shocking data to the underlying mechanisms: gut destruction, visceral fat accumulation, brain hijacking, and toxic exposure, this episode exposes the real cost of ultra-processed food and gives you the tools to reclaim control of your health and your life. What You'll Learn The shocking stat: 5% increased heart risk per serving of ultra-processed food Why ultra-processed foods act like compounding debt on your health The difference between calories vs chemical toxicity in food How emulsifiers and additives destroy your gut microbiome Why ultra-processed foods increase visceral fat around your organs How these foods are engineered to override your brain's satiety signals The hidden toxins from processing and packaging (PFAS, bisphenols, AGEs) Why this crisis disproportionately impacts certain communities The truth: you can't "out-exercise" ultra-processed food damage Practical ways to transition back to real, whole foods Chapters 00:00:04 – Opening: SuperLife mission and setting the stage 00:00:33 – Sponsor: Alkemis Paint and hidden indoor toxicity 00:01:24 – Why conventional paints off-gas harmful chemicals for years 00:02:27 – Cradle-to-Cradle certification and non-toxic living 00:03:24 – Entering the episode: the 5% heart risk question 00:03:34 – The shocking claim: every serving increases heart risk 00:04:16 – Ultra-processed food as "compounding debt" 00:05:08 – Leaning into discomfort as a path to growth 00:06:33 – The convenience trap: food delivered instantly 00:07:15 – The real cost: trading time for lifespan 00:08:07 – 2026 study overview (MESA dataset, 6,800 participants) 00:09:01 – 5.1% increased cardiovascular risk per serving explained 00:09:29 – 66.8% higher risk in high-consumption groups 00:10:08 – Risk is independent of calories, weight, and fitness 00:10:56 – "This is not a calorie story—it's a chemistry story" 00:11:10 – Racial disparities and food system inequality 00:12:08 – Additional studies confirm elevated heart risk 00:13:04 – Global meta-analysis: over 1 million participants 00:13:26 – The conclusion: the science is no longer debatable 00:14:18 – Sponsor: Shakeology and nutrient density 00:15:36 – What is ultra-processed food? (NOVA classification) 00:16:18 – Examples: chips, cereals, protein bars, fast food 00:16:57 – "These foods are engineered—not real food" 00:17:00 – Mechanism #1: gut microbiome disruption 00:18:03 – Emulsifiers and inflammation explained 00:18:49 – Gut inflammation triggers systemic disease 00:19:18 – Mechanism #2: visceral fat accumulation 00:19:56 – Why visceral fat is more dangerous than visible fat 00:20:18 – Mechanism #3: brain hijacking and satiety override 00:20:47 – Engineered foods and addictive eating patterns 00:21:04 – Mechanism #4: toxins from processing and packaging 00:21:30 – PFAS, bisphenols, and chemical contamination 00:21:37 – The solution: whole food first 00:22:02 – Breaking habits and reclaiming control 00:22:20 – Simple swaps: fruit, nuts, whole ingredients 00:23:00 – "If you can't trace it back to a real food, put it down" 00:23:32 – Making whole food convenient 00:24:06 – Batch cooking and preparation strategies 00:24:16 – Personal story: losing a friend to diet-related illness 00:24:40 – The emotional reality: this is life or death 00:25:00 – Community support and accountability 00:25:25 – Call to action: share this message 00:25:41 – Closing: courage, awareness, and living a SuperLife 00:26:23 – Outro Thank You to Our Sponsors: Shakeology: Get 15% off with code DARINO1BODI at Shakeology.com. Alkemis Paint: Go to https://alkemispaint.com/ and use code DARIN10 for 10% off your order. Join the SuperLife Patreon: This is where Darin now shares the deeper work: - weekly voice notes - ingredient trackers - wellness challenges - extended conversations - community accountability - sovereignty practices Join now for only $7.49/month at https://patreon.com/darinolien Connect with Darin Olien: Website: darinolien.com Instagram: @darinolien Book: Fatal Conveniences Platform & Products: superlife.com New Show: Roadmap to Happiness Key Takeaway "Every time you reach for ultra-processed food, you're not just making a small decision—you're compounding a biological cost that your body has to pay later. But the moment you become aware, you reclaim your power. Because the same way those choices can slowly take your health away… different choices, repeated daily, can give it all back." Bibliography/Sources Primary Study — News Hook Haidar, A., Rikhi, R., Watson, K. E., Wood, A. C., & Shapiro, M. D. (2026). Association between ultraprocessed food consumption and cardiovascular disease risk: MESA. JACC: Advances. https://doi.org/10.1016/j.jacadv.2025.102516 Supporting Studies — 2026 Willett, Y., Yang, C., Dunn, J., et al. (2026). Consumption of ultra-processed foods and increased risks of cardiovascular disease in U.S. adults. The American Journal of Medicine. https://doi.org/10.1016/j.amjmed.2026.01.012 Systematic Reviews & Meta-Analyses Dose-response meta-analysis: UPF consumption and cardiovascular events risk — 20 studies, 1.1M participants. (2024). eClinicalMedicine. https://doi.org/10.1016/j.eclinm.2024.102480 Ultra-processed foods and cardiovascular disease: Analysis of three large US prospective cohorts and a systematic review and meta-analysis. (2024). The Lancet Regional Health – Americas. https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(24)00186-8/fulltext Mechanisms — Gut, Inflammation & Additives Ultra-processed foods and cardiovascular diseases: Potential mechanisms of action. (2021). Advances in Nutrition. https://pmc.ncbi.nlm.nih.gov/articles/PMC8483964/ Ultra-processed foods and food additives in gut health and disease. (2024). Nature Reviews. https://pubmed.ncbi.nlm.nih.gov/38388570/ Ultra-processed foods and incident cardiovascular disease in the Framingham Offspring Study. (2021). Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2021.01.047 Ultraprocessed foods and their association with cardiometabolic health: A science advisory from the American Heart Association. (2023). Circulation. https://www.ahajournals.org/doi/10.1161/CIR.0000000000001365 Visceral Fat Konieczna, J., et al. (n.d.). Contribution of ultra-processed foods in visceral fat deposition: Prospective analysis nested in the PREDIMED-Plus trial. Clinical Nutrition. https://www.explorationpub.com/Journals/edd/Article/100523 NOVA Classification Monteiro, C. A., Cannon, G., Levy, R. B., et al. (2019). Ultra-processed foods: What they are and how to identify them. Public Health Nutrition, 22(5), 936–941. https://pubmed.ncbi.nlm.nih.gov/30744710/ Policy & Public Health Context American College of Cardiology. (2025). ACC 2025 concise clinical guidance: Front-of-package labeling endorsement. Journal of the American College of Cardiology. U.S. Departments of Agriculture and Health and Human Services. (n.d.). Dietary guidelines for Americans, 2025–2030. https://www.dietaryguidelines.gov General Coverage — News Hook Food Safety Magazine. (2026, April). Study links diets high in ultra-processed foods to increased heart attack, stroke risk. https://www.food-safety.com/articles/11290-study-links-diets-high-in-ultra-processed-foods-to-increased-heart-attack-stroke-risk ScienceDaily. (2026, March). Ultra-processed foods linked to 67% higher risk of heart attack and stroke. https://www.sciencedaily.com/releases/2026/03/260319074604.htm

Unearthed! In Spring 2026, Part 2

Play Episode Listen Later Apr 22, 2026 38:48 Transcription Available

Part one of this quarter's edition of Unearthed! includes animals, artwork, edibles and potables, shipwrecks, potpourri. Research: Abdallah, Hannah. “Analysis of charred food in pot reveals that prehistoric Europeans had surprisingly complex cuisines.” EurekAlert. 3/4/2025. https://www.eurekalert.org/news-releases/1117763 Almeroth-Williams, Thomas. “British redcoat’s lost memoir reveals harsh realities of life as a disabled veteran.” EurekAlert. 1/14/2026. https://www.eurekalert.org/news-releases/1111595 Anderson, Sonja. “Does This Skeleton Found Beneath a Dutch Church Belong to D’Artagnan, the Man Who Inspired ‘The Three Musketeers’?” Smithsonian. 3/27/2026. https://www.smithsonianmag.com/smart-news/this-skeleton-found-beneath-the-floor-of-a-dutch-church-may-belong-to-dartagnan-the-fourth-musketeer-180988448/ Anderson, Sonja. “Historians Thought This Rare Renaissance Portrait by One of the First Famous Female Artists Was Lost to History—Until It Surfaced in North Carolina.” 2/3/2026. https://www.smithsonianmag.com/smart-news/historians-thought-this-rare-renaissance-portrait-by-one-of-the-first-famous-female-artists-was-lost-to-history-until-it-surfaced-in-north-carolina-180988120/ Anderson, Sonja. “Hundreds of Ancient Roman Blade Sharpeners Emerge From a Riverbank in England, Revealing the Ruins of a 2,000-Year-Old Whetstone Factory.” Smithsonian. 1/20/2026. https://www.smithsonianmag.com/smart-news/hundreds-of-ancient-roman-blade-sharpeners-emerge-from-a-riverbank-in-england-revealing-the-ruins-of-a-2000-year-old-whetstone-factory-180988016/ Anderson, Sonja. “The Italian Government Just Paid Nearly $35 Million for a Rare Caravaggio Portrait—One of the Most Expensive Artworks It’s Ever Acquired.” Smithsonian. 3/16/2026. https://www.smithsonianmag.com/smart-news/the-italian-government-just-paid-nearly-35-million-for-a-rare-Caravaggio-portrait-one-of-the-most-expensive-artworks-its-ever-acquired-180988344/ Arnold, Paul. “Poop as medicine? A Roman vial's chemistry backs up ancient medical texts.” Phys.org. 2/4/2026. https://phys.org/news/2026-02-poop-medicine-roman-vial-chemistry.html Arnold, Paul. “Scents of the afterlife: Identifying embalming recipes by 'sniffing' the air around Egyptian mummies.” Phys.org. 2/5/2026. https://phys.org/news/2026-02-scents-afterlife-embalming-recipes-sniffing.html#google_vignette Bacon, Jordan. “English history’s biggest march is a myth – King Harold sailed to the Battle of Hastings.” EurekAlert. 3/20/2026. https://www.eurekalert.org/news-releases/1120082 Bastola, Kunjal. “A Groundskeeper Noticed a Sinkhole on a Golf Course. It Turned Out to Be a Wine Cellar Full of Empty Bottles, Untouched for More Than 100 Years.” Smithsonian. 3/19/2026. https://www.smithsonianmag.com/smart-news/a-groundskeeper-noticed-a-sinkhole-on-a-golf-course-it-turned-out-to-be-a-wine-cellar-full-of-empty-bottles-untouched-for-more-than-100-years-180988379/ Bastola, Kunjal. “A Little Boy’s Library Book Was Due in 1989. Thirty-Six Years Later, He Realized His Parents Had Never Returned It.” Smithsonian. 1/26/2026. https://www.smithsonianmag.com/smart-news/a-little-boys-library-book-was-due-in-1989-thirty-six-years-later-he-realized-his-parents-had-never-returned-it-180988046/ Baum, Stephanie. “Ancient parrot DNA reveals sophisticated, long-distance animal trade network pre-dating the Inca Empire.” 3/10/2026. https://phys.org/news/2026-03-ancient-parrot-dna-reveals-sophisticated.html Baum, Stephanie. “From the Late Bronze Age to today, the Old Irish Goat carries 3,000 years of Irish history.” 2/26/2026. https://phys.org/news/2026-02-late-bronze-age-today-irish.html Benzine, Vittoria. “What Did Pompeii Smell Like? A New Study Analyzes Its Ancient Incense.” Artnet. 3/31/2026. https://news.artnet.com/art-world/pompeii-ritual-incense-study-2760240 Brooks, James. “Danish warship sunk by Nelson’s British fleet discovered after 225 years.” Associated Press. 4/2/2026. https://apnews.com/article/denmark-archaeologists-warship-nelson-copenhagen-dannebroge-lynetteholm-4519533d9e774a490f6020e893634e09 Carvajal, Guillermo. “Archaeologists achieve a historic milestone by dating French cave paintings with carbon-14 for the first time.” 3/10/2025. https://www.labrujulaverde.com/en/2026/03/archaeologists-achieve-a-historic-milestone-by-dating-french-cave-paintings-with-carbon-14-for-the-first-time/ Clayworth, Liv. “Bird poop powered the rise of the Chincha Kingdom, archaeologists find.” EurekAlert. 2/11/2026. https://www.eurekalert.org/news-releases/1115214 “Lost page of the Archimedes Palimpsest identified in Blois, central France.” Phys.org. 3/9/2026. https://phys.org/news/2026-03-lost-page-archimedes-palimpsest-blois.html Ehrlich, Claudia. “Signs on Stone Age objects: Precursor to written language dates back 40,000 years.” EurekAlert. 2/23/2026. https://www.eurekalert.org/news-releases/1117179 Ferrer, Isabel. “Is d’Artagnan lying beneath a church in Maastricht? DNA will determine if remains found are those of the famous musketeer.” El Pais. 3/25/2025. https://english.elpais.com/international/2026-03-25/is-dartagnan-lying-beneath-a-church-in-maastricht-dna-will-determine-if-remains-found-are-that-of-the-famous-musketeer.html?outputType=amp Gebauer, Kathryn. “Groundbreaking discovery reveals Africa’s oldest cremation pyre and complex ritual practices.” EurekAlert. 1/1/2016. https://www.eurekalert.org/news-releases/1111191 Harley, Sadie. “Iron Age dental plaque reveals Scythians consumed milk from horses and ruminants.” Phys.org. 1/21/2026. https://phys.org/news/2026-01-iron-age-dental-plaque-reveals.html He, Ye. “Singapore’s first ancient shipwreck reveals record cargo of Yuan dynasty blue-and-white porcelain.” EurekAlert. 2/12/2026. https://www.eurekalert.org/news-releases/1116512 Johansen, Rikke Tørnsø. “Archaeologists reveal a medieval super ship: "It's the World’s largest cog".” Vikingeskibs Museet. 12/22/2025. https://www.vikingeskibsmuseet.dk/en/news/archaeologists-reveal-a-medieval-super-ship-its-the-worlds-largest-cog Kasal, Krystal. “Hannibal's famous war elephants: Single bone in Spain offers first direct evidence.” Phys.org. 2/5/2026. https://phys.org/news/2026-02-hannibal-famous-war-elephants-bone.html Kasal, Krystal. “Oldest known sewn hide and other artifacts from Oregon caves shed light on early clothing in harsh climates.” Phys.org. 2/10/2026. https://phys.org/news/2026-02-oldest-sewn-artifacts-oregon-caves.html Killgrove, Kristina. “Romans used human feces as medicine 1,900 years ago — and used thyme to mask the smell.” 1/29/2026. https://www.livescience.com/archaeology/romans/romans-used-human-feces-as-medicine-1-900-years-ago-and-used-thyme-to-mask-the-smell Killgrove, Kristina. “Stone Age woman was buried like a man, revealing flexible gender roles 7,000 years ago in Hungary.” LiveScience. 3/3/2026. https://www.livescience.com/archaeology/stone-age-woman-was-buried-like-a-man-revealing-flexible-gender-roles-7-000-years-ago-in-hungary Koc University. “Earliest evidence of indigo-dyed textiles and single-needle knitting discovered in Bronze Age Anatolia.” Phys.org. 2/21/2026. https://phys.org/news/2026-02-earliest-evidence-indigo-dyed-textiles.html Kuta, Sarah. “Did Neanderthals Use Birch Bark Tar as an Antibiotic to Treat Wounds and Infections?” Smithsonian. 3/30/2026. https://www.smithsonianmag.com/smart-news/did-neanderthals-use-birch-bark-tar-as-an-antibiotic-to-treat-wounds-and-infections-180988393/ Kuta, Sarah. “Ostrich Eggshells Suggest Our Ancestors May Have Understood Basic Geometry 60,000 Years Ago.” Smithsonian. 3/9/2026. https://www.smithsonianmag.com/smart-news/these-intricately-decorated-ostrich-eggshells-suggest-our-ancestors-may-have-understood-basic-geometry-60000-years-ago-180988315/ Kuta, Sarah. “Ötzi the Iceman May Have Carried a Cancer-Causing Strain of HPV, a Common Virus Still Plaguing Humans Today.” Smithsonian. 1/20/2026. https://www.smithsonianmag.com/smart-news/otzi-the-iceman-may-have-carried-a-cancer-causing-strain-of-hpv-a-common-virus-still-plaguing-humans-today-180988024/ Kuta, Sarah. “Shipwreck Timbers Appeared on a Beach After a Storm. They Had Been Buried Beneath the Sand Since the 17th Century.” Smithsonian. 3/2/2026. https://www.smithsonianmag.com/smart-news/shipwreck-timbers-appeared-on-a-beach-after-a-storm-they-had-been-buried-beneath-the-sand-since-the-17th-century-180988260/ Lawson-Tancred, Jo. “Salvador Dalí’s Largest Work Snapped Up by Florida Museum.” Artnet. 3/27/2026. https://news.artnet.com/market/salvador-dali-largest-work-bonhams-sale-2749246 Lock, Lisa. “Ancient DNA finds 15,800-year-old dogs in Anatolia, buried like humans.” Phys.org. 3/28/2026. https://phys.org/news/2026-03-ancient-dna-year-dogs-anatolia.html Lock, Lisa. “Are one in 200 men really related to Genghis Khan? Maybe not, according to a new study.” Phys.org. 2/21/2026. https://phys.org/news/2026-02-men-genghis-khan.html Lucibella, Michael. “Prehistoric tool made from elephant bone is the oldest discovered in Europe.” EurekAlert. 1/26/2026. https://www.eurekalert.org/news-releases/1113140 Luscombe, Richard. “Mass grave in Jordan sheds new light on world’s earliest recorded pandemic.” The Guardian. 1/31/2026. https://www.theguardian.com/science/2026/jan/31/plague-of-justinian-pandemic net. “Did King Harold Sail to Hastings? New Study Sparks Debate Among Historians.” 3/2026. https://www.medievalists.net/2026/03/did-king-harold-sail-to-hastings-new-study-sparks-debate-among-historians/ net. “Viking-Age Woman Buried with Her Dog in Norway.” 3/2026. https://www.medievalists.net/2026/03/viking-age-woman-buried-with-her-dog-in-norway/ Newcastle University Press Office. “5,300-year-old ‘bow drill’ rewrites story of ancient Egyptian tools.” 2/9/2026. https://www.ncl.ac.uk/press/articles/latest/2026/02/ancientegyptiandrillbit/ Noraz, R., Chauvey, L., Wagner, S. et al. Ancient DNA reveals 4000 years of grapevine diversity, viticulture and clonal propagation in France. Nat Commun 17, 2494 (2026). https://doi.org/10.1038/s41467-026-70166-z Nordin, Gunilla. “World’s oldest arrow poison – 60,000-year-old traces reveal early advanced hunting techniques.” 1/7/2026. https://www.eurekalert.org/news-releases/1111624 Parco Archaeologico de Ercolano. “Archaeology: New precious decorations discovered at Villa Sora in the Herculaneum Park.” 2/5/2026. https://ercolano.cultura.gov.it/archaeology-new-precious-decorations-discovered-at-villa-sora-in-the-herculaneum-park/?lang=en Paul, Andrew. “Hiker finds 3,000-year-old bull sculpture in Spain.” Popular Science. 3/17/2026. https://www.popsci.com/science/hiker-finds-bronze-age-bull-spain/ Potter, Lisa. “A wild potato that changed the story of agriculture in the American Southwest.” EurekAlert. 1/21/2026. https://www.eurekalert.org/news-releases/1113056 “Digital scans unveil new love notes and sketches on ancient Pompeii wall.” 1/19/2026. https://www.reuters.com/science/digital-scans-unveil-new-love-notes-sketches-ancient-pompeii-wall-2026-01-19/ Richard L. 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Unearthed! In Spring 2026, Part 1