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In this episode I'm joined by Lyman Stone and Diana Fleischman for a debate on eugenics – specifically, Diana's argument that most people support ‘negative eugenic' policies to some degree, and that governments ought to go further by encouraging the use of sterilisation or long term contraception among, for instance, drug addicts.Lyman Stone is the Director of Research of the consulting firm Demographic Intelligence, the director of the Pronatalism Initiative at the Institute for Family Studies, and an author on Substack - Diana Fleischman is an evolutionary psychologist, Associate Research Professor at the University of New Mexico, and author of the Dissentient Substack - https://dissentient.substack.comDiscussed in the episode:* Diana's essay ‘You're probably a eugenicist' https://dissentient.substack.com/p/eugenicist* Shor, E., & Simchai, D. (2009). Incest avoidance, the incest taboo, and social cohesion: Revisiting Westermarck and the case of the Israeli kibbutzim. American Journal of Sociology, 114(6), 1803–1842.* Gipson, J. D., Bornstein, M., Berger, A., & Rocca, C. H. (2021). Desire to avoid pregnancy and contraceptive use among female methadone patients in Los Angeles. Contraception, 103(5), 322–327* Donohue, J. J., & Levitt, S. D. (2001). The Impact of Legalized Abortion on Crime. The Quarterly Journal of Economics, 116(2), 379–420. https://doi.org/10.1162/00335530151144050 This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.louiseperry.co.uk/subscribe

Deep State Democrats PANIC After Trump Calls Out Their Seditious Video Demanding US Military Insubordination

Trump Signs Epstein Files Bill, Prepares To Meet With NYC Socialist Mayor Mamdani, Approves 28-Point Russia/Ukraine Peace Plan

Epstein Files Bill Heads To Trump's Desk, J6 Pipe Bomb False Flag Collapses On Deep State & Economy Becomes Top Midterm Issue

Language assessments shape who gets services, how goals are written, and how progress is measured, but there are many misconceptions about how to follow best-practices when doing an evaluation. In this three-part series, bilingual SLPs Destiny Johnson and Tiffany Shahoumian-Ruiz join me to dig into the science, the myths, and the policies that shape evaluation practices in schools.Across these conversations, we explore:Sensitivity, specificity, reference standards, and diagnostic accuracyHow test development has evolved over time and why this matters Why the same cut-off score shouldn't apply across all testsThe math behind using two norm-referenced tests, and why it may complicate rather than clarify in some casesOther reasons we test beyond diagnosis (treatment planning, severity, monitoring progress)How do we do we to “sell” the concept of dynamic assessment to administratorsCase studies that show the pitfalls of over-reliance on standardized scoresMisconceptions clinicians often hold, and what they should know about assessmentDifferences in state eligibility standards, and what this means for service decisionsThis series is part myth-busting, part practical strategies, and part advocacy playbook—perfect for clinicians who want to move beyond compliance-driven evaluations toward assessments that truly reflect students' needs.You can listen to Part 1 of the series here.Destiny Johnson, M.S., CCC-SLP, is a bilingual speech-language pathologist (English/Spanish) with a deep passion for culturally responsive assessment and treatment practices, as well as advocating for policy change. She has presented on dynamic assessment at the CSHA Convergence 2024, focusing on the importance of dynamic assessment in bilingual children. Destiny has experience working as a school-based SLP, in private practice, and in early intervention. She is also the founder and CEO of Multimodal Communication Speech Clinic P.C.Connect with Destiny on Instagram @destinyjohnsonslp, on her private practice website here, and on LinkedIn here.Listen to Destiny's previous episode on De Facto Leaders here: EP 187: Dynamic Assessment: Evaluations are a process, not a test (with Destiny Johnson)Tiffany Shahoumian-Ruiz is a bilingual high school SLP from Southern California who has primarily worked in the school systems and has experience at both the elementary and secondary level. She's also a member of Language Therapy Advance Foundations, and is involved in state and local advocacy work relating to dynamic assessments and special education eligibility.Connect with Tiffany on Instagram @tiffany.shahoumianListen to Tiffany's previous episode on De Facto Leaders here: High school language therapy: Do we still have time to make an impact? (with Tiffany Shahoumian-Ruiz)In this episode, I mention Language Therapy Advance Foundations, my program that gives SLPs and other service providers create a system for language therapy. You can learn more about the program here.Additional Resources Mentioned in the episode:Daub, O., Cunningham, B. J., Bagatto, M. P., Johnson, A. M., Kwok, E. Y., Smyth, R. E., & Oram Cardy, J. (2021). Adopting a conceptual validity framework for testing in speech-language pathology. American Journal of Speech-Language Pathology, 30(4), 1894–1908. https://doi.org/10.1044/2021_AJSLP-20-00032Spaulding, T. J., Plante, E., & Farinella, K. A. (2006). Eligibility criteria for language impairment: Is the low end of normal always appropriate? Language, Speech, and Hearing Services in Schools, 37(1), 61–72. https://doi.org/10.1044/0161-1461(2006/007)DYMOND Norm-Referenced Dynamic AssessmentBilingual English-Spanish Assessment (BESA) We're thrilled to be sponsored by IXL. IXL's comprehensive teaching and learning platform for math, language arts, science, and social studies is accelerating achievement in 95 of the top 100 U.S. school districts. Loved by teachers and backed by independent research from Johns Hopkins University, IXL can help you do the following and more:Simplify and streamline technologySave teachers' timeReliably meet Tier 1 standardsImprove student performance on state assessments

Ever wonder if it is ok (or even good!?) to follow a vegetarian or vegan diet with kidney stones? Melanie breaks down the benefits and risks in this episode. Blog: Magnesium & Kidney Stones: The 411 Blog: Oxalate in Coconut Milk: And Other Plant Based Milks Blog: Calcium Sources for Kidney Stones References: 1. Zayed S, Goldfarb DS, Joshi S. Popular Diets and Kidney Stones. Advances in Kidney Disease and Health. 2023;30(6):529-536. 2. Rodriguez A, Curhan GC, Gambaro G, Taylor EN, Ferraro PM. Mediterranean diet adherence and risk of incident kidney stones. The American Journal of Clinical Nutrition. 2020;111(5):1100-1106.  3. Maddahi N, Aghamir SMK, Moddaresi SS, Mirzaei K, Alizadeh S, Yekaninejad MS. The association of Dietary Approaches to Stop Hypertension-style diet with urinary risk factors of kidney stones formation in men with nephrolithiasis. Clinical Nutrition ESPEN. 2020;39:173-179.  4. Noori N, Honarkar E, Goldfarb DS, et al. Urinary Lithogenic Risk Profile in Recurrent Stone Formers With Hyperoxaluria: A Randomized Controlled Trial Comparing DASH (Dietary Approaches to Stop Hypertension)-Style and Low-Oxalate Diets. American Journal of Kidney Diseases. 2014;63(3):456-463.    Submit a question for Melanie to answer on the podcast! Connect with The Kidney Dietitian! Work with Us! |  Instagram | Facebook | Pinterest | Facebook Group | Newsletter www.thekidneydietitian.org FREE Webinar: The 3-Step Method to Prevent Kidney Stones All information in this podcast is meant for educational purposes only and should not be used in place of advice from a medical professional.  

Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Evan S. Dellon, MD, and Elizabeth T. Jensen, PhD, about a paper they published on predictors of patients receiving no medication for treatment of eosinophilic esophagitis. Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own.   Key Takeaways: [:52] Co-host Ryan Piansky introduces the episode, brought to you thanks to the support of Education Partners GSK, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz.   [1:14] Holly introduces today's topic, predictors of not using medication for EoE, and today's guests, Dr. Evan Dellon and Dr. Elizabeth Jensen.   [1:29] Dr. Dellon is an Adjunct Professor of Epidemiology at the University of North Carolina School of Medicine in Chapel Hill. He is also the Director of the UNC Center for Esophageal Diseases and Swallowing.   [1:42] Dr. Dellon's main research interest is in the epidemiology, pathogenesis, diagnosis, treatment, and outcomes of eosinophilic esophagitis (EoE) and eosinophilic GI diseases (EGIDs).   [1:55] Dr. Jensen is a Professor of Epidemiology with a specific expertise in reproductive, perinatal, and pediatric epidemiology. She has appointments at both Wake Forest University School of Medicine and the University of North Carolina at Chapel Hill.   [2:07] Her research primarily focuses on etiologic factors in the development of pediatric immune-mediated chronic diseases, including understanding factors contributing to disparities in health outcomes.   [2:19] Both Dr. Dellon and Dr. Jensen also serve on the Steering Committee for EGID Partners Registry.   [2:24] Ryan thanks Dr. Dellon and Dr. Jensen for joining the podcast today.   [2:29] Dr. Dellon was the first guest on this podcast. It is wonderful to have him back for the 50th episode! Dr. Dellon is one of Ryan's GI specialists. Ryan recently went to North Carolina to get a scope with him.   [3:03] Dr. Dellon is an adult gastroenterologist at the University of North Carolina at Chapel Hill. He directs the Center for Esophageal Diseases and Swallowing. Clinically and research-wise, he is focused on EoE and other eosinophilic GI diseases.   [3:19] His research interests span the entire field, from epidemiology, diagnosis, biomarkers, risk factors, outcomes, and a lot of work, more recently, on treatments.   [3:33] Dr. Jensen has been on the podcast before, on Episode 27. Holly invites Dr. Jensen to tell the listeners more about herself and her work with eosinophilic diseases.   [3:46] Dr. Jensen has been working on eosinophilic gastrointestinal diseases for about 15 years. She started some of the early work around understanding possible risk factors for the development of disease.   [4:04] She has gone on to support lots of other research projects, including some with Dr. Dellon, where they're looking at gene-environment interactions in relation to developing EoE.   [4:15] She is also looking at reproductive factors as they relate to EoE, disparities in diagnosis, and more. It's been an exciting research trajectory, starting with what we knew very little about and building to an increasing understanding of why EoE develops.   [5:00] Dr. Dellon explains that EoE stands for eosinophilic esophagitis, a chronic allergic condition of the esophagus.   [5:08] You can think of EoE as asthma of the esophagus or eczema of the esophagus, although in general, people don't grow out of EoE, like they might grow out of eczema or asthma. When people have EoE, it is a long-term condition.   [5:24] Eosinophils are a type of white blood cell, specializing in allergy responses. Normally, they are not in the esophagus. When we see them there, we worry about an allergic process. When that happens, that's EoE.   [5:40] Over time, the inflammation seen in EoE and other allergic cell activity causes swelling and irritation in the esophagus. Early on, this often leads to a range of upper GI symptoms — including poor growth or failure to thrive in young children, abdominal pain, nausea, and symptoms that can mimic reflux.   [5:58] In older kids, symptoms are more about trouble swallowing. That's because the swelling that happens initially, over time, may turn into scar tissue. So the esophagus can narrow and cause swallowing symptoms like food impaction.   [6:16] Ryan speaks of living with EoE for decades and trying the full range of treatment options: food elimination, PPIs, steroids, and, more recently, biologics.   [6:36] Dr. Dellon says Ryan's history is a good overview of how EoE is treated. There are two general approaches to treating the underlying condition: using medicines and/or eliminating foods that we think may trigger EoE from the diet.   [6:57] For a lot of people, EoE is a food-triggered allergic condition.   [7:01] The other thing that has to happen in parallel is surveying for scar tissue in the esophagus. If that's present and people have trouble swallowing, sometimes stretching the esophagus is needed through esophageal dilation.   [7:14] There are three categories of medicines used for treatment. Proton pump inhibitors are reflux meds, but they also have an anti-allergy effect in the esophagus.   [7:29] Topical steroids are used to coat the esophagus and produce an anti-inflammatory effect. The FDA has approved a budesonide oral suspension for that.   [7:39] Biologics, which are generally systemic medications, often injectable, can target different allergic factors. Dupilumab is approved now, and there are other biologics that are being researched as potential treatments.   [7:51] Even though EoE is considered an allergic condition, we don't have a test to tell people what they are allergic to. If it's a food allergy, we do an empiric elimination diet because allergy tests aren't accurate enough to tell us what the EoE triggers are.   [8:10] People will eliminate foods that we know are the most common triggers, like milk protein, dairy, wheat, egg, soy, and other top allergens. You can create a diet like that and then have a response to the diet elimination.   [8:31] Dr. Jensen and Dr. Dellon recently published an abstract in the American Journal of Gastroenterology about people with EoE who are not taking any medicine for it. Dr. Jensen calls it a real-world data study, leveraging electronic health record patient data.   [8:51] It gives you an impression of what is actually happening, in terms of treatments for patients, as opposed to a randomized control trial, which is a fairly selected patient population. This is everybody who has been diagnosed, and then what happens with them.   [9:10] Because of that, it gives you a wide spectrum of patients. Some patients are going to be relatively asymptomatic. It may be that we arrived at their diagnosis while working them up for other potential diagnoses.   [9:28] Other patients are going to have rather significant impacts from the disease. We wanted to get an idea of what is actually happening out there with the full breadth of the patient population that is getting diagnosed with EoE.   [9:45] Dr. Jensen was not surprised to learn that there are patients who had no pharmacologic treatment.   [9:58] Some patients are relatively asymptomatic, and others are not interested in pursuing medications initially or are early in their disease process and still exploring dietary treatment options.   [10:28] Holly sees patients from infancy to geriatrics, and if they're not having symptoms, they wonder why bother treating it.   [10:42] Dr. Jensen says it's a point of debate on the implications of somebody who has the disease and goes untreated. What does that look like long-term? Are they going to develop more of that fibrostenotic pattern in their esophagus without treatment?   [11:07] This is a question we're still trying to answer. There is some suggestion that for some patients who don't manage their disease, we very well may be looking at a food impaction in the future.   [11:19] Dr. Dellon says we know overall for the population of EoE patients, but it's hard to know for a specific patient. We have a bunch of studies now that look at how long people have symptoms before they're diagnosed. There's a wide range.   [11:39] Some people get symptoms and get diagnosed right away. Others might have symptoms for 20 or 30 years that they ignore, or don't have access to healthcare, or the diagnosis is missed.   [11:51] What we see consistently is that people who may be diagnosed within a year or two may only have a 10 or 20% chance of having that stricture and scar tissue in the esophagus, whereas people who go 20 years, it might be 80% or more.   [12:06] It's not everybody who has EoE who might end up with that scar tissue, but certainly, it's suggested that it's a large majority.   [12:16] That's before diagnosis. We have data that shows that after diagnosis, if people go a long time without treatment or without being seen in care, they also have an increasing rate of developing strictures.    [12:29] In general, the idea is yes, you should treat EoE, because on average, people are going to develop scar tissue and more symptoms. For the patient in front of you with EoE but no symptoms, what are the chances it's going to get worse? You don't know.   [13:04] There are two caveats with that. The first is what we mean by symptoms. Kids may have vomiting and growth problems. Adults can eat carefully, avoiding foods that hang up in the esophagus, like breads and overcooked meats, sticky rice, and other foods.   [13:24] Adults can eat slowly, drink a lot of liquid, and not perceive they have symptoms. When someone tells Dr. Dellon they don't have symptoms, he will quiz them about that. He'll even ask about swallowing pills.    [13:40] Often, you can pick up symptoms that maybe the person didn't even realize they were having. In that case, that can give you some impetus to treat.   [13:48] If there really are no symptoms, Dr. Dellon thinks we're at a point where we don't really know what to do.   [13:54] Dr. Dellon just saw a patient who had a lot of eosinophils in their small bowel with absolutely no GI symptoms. He said, "I can't diagnose you with eosinophilic enteritis, but you may develop symptoms." People like that, he will monitor in the clinic.   [14:14] Dr. Dellon will discuss it with them each time they come back for a clinic visit.   [14:19] Holly is a speech pathologist, but also sees people for feeding and swallowing. The local gastroenterologist refers patients who choose not to treat their EoE to her. Holly teaches them things they should be looking out for.   [14:39] If your pills get stuck or if you're downing 18 ounces during a mealtime, maybe it's time to treat it. People don't see these coping mechanisms they use that are impacting their quality of life. They've normalized it.   [15:30] Dr. Dellon says, of these people who aren't treated, there's probably a subset who appropriately are being observed and don't have a medicine treatment or are on a diet elimination.   [15:43] There's also probably a subset who are inappropriately not on treatment. It especially can happen with students who were under good control with their pediatric provider, but moved away to college and didn't transfer to adult care.   [16:08] They ultimately come back with a lot of symptoms that have progressed over six to eight years.   [16:18] Ryan meets newly diagnosed adult patients at APFED's conferences, who say they have no symptoms, but chicken gets caught in their throat. They got diagnosed when they went to the ER with a food impaction.   [16:38] Ryan says you have to wonder at what point that starts to get reflected in patient charts. Are those cases documented where someone is untreated and now has EoE?   [16:49] Ryan asks in the study, "What is the target EGID Cohort and why was it selected to study EoE? What sort of patients were captured as part of that data set?"   [16:58] Dr. Jensen said they identified patients with the ICD-10 code for a diagnosis of EoE. Then they looked to see if there was evidence of symptoms or complications in relation to EoE. This was hard; some of these are relatively non-specific symptoms.   [17:23] These patients may have been seeking care and may have been experiencing some symptoms that may or may not have made it into the chart. That's one of the challenges with real-world data analyses.   [17:38] Dr. Jensen says they are using data that was collected for documenting clinical care and for billing for clinical care, not for research, so it comes with some caveats when doing research with this data.   [18:08] Research using electronic health records gives a real-world perspective on patients who are seeking care or have a diagnosis of EoE, as opposed to a study trying to enroll a patient population that potentially isn't representative of the breadth of individuals living with EoE.   [18:39] Dr. Dellon says another advantage of real-world data is the number of patients. The largest randomized controlled trials in EoE might have 400 patients, and they are incredibly expensive to do.   [18:52] A study of electronic health records (EHR) is reporting on the analysis of just under 1,000. The cohort, combined from three different centers, has more than 1,400 people, a more representative, larger population.    [19:16] Dr. Dellon says when you read the results, understand the limitations and strengths of a study of health records, to help contextualize the information.   [19:41] Dr. Dellon says it's always easier to recognize the typical presentations. Materials about EoE and studies he has done that led to medicine approvals have focused on trouble swallowing. That can be relatively easily measured.   [20:01] Patients often come to receive care with a food impaction, which can be impactful on life, and somewhat public, if in a restaurant or at work. Typical symptoms are also the ones that get you diagnosed and may be easier to treat.   [20:26] Dr. Dellon wonders if maybe people don't treat some of the atypical symptoms because it's not appreciated that they can be related to EoE.   [20:42] Holly was diagnosed as an adult. Ryan was diagnosed as a toddler. Holly asks what are some of the challenges people face in getting an EoE diagnosis.   [20:56] Dr. Jensen says symptoms can sometimes be fairly non-specific. There's some ongoing work by the CEGIR Consortium trying to understand what happens when patients come into the emergency department with a food bolus impaction.   [21:28] Dr. Jensen explains that we see there's quite a bit of variation in how that gets managed, and if they get a biopsy. You have to have a biopsy of the esophagus to get a diagnosis of EoE.   [21:45] If you think about the steps that need to happen to get a diagnosis of EoE, that can present barriers for some groups to ultimately get that diagnosis.   [21:56] There's also been some literature around a potential assumption about which patients are more likely to be at risk. Some of that is still ongoing. We know that EoE occurs more commonly in males in roughly a two-to-one ratio. Not exclusively in males, obviously, but a little more often in males.   [22:20] We don't know anything about other groups of patients that may be at higher risk. That's ongoing work that we're still trying to understand. That in itself can also be a barrier when there are assumptions about who is or isn't likely to have EoE.   [23:02] Dr. Dellon says that in adolescents and adults, the typical symptoms are trouble swallowing and food sticking, which have many causes besides EoE, some of which are more common.   [23:18] In that population, heartburn is common. Patients may report terrible reflux that, on questioning, sounds more like trouble swallowing than GERD. Sometimes, with EoE, you may have reflux that doesn't improve. Is it EoE, reflux, or both?   [24:05] Some people will have chest discomfort. There are some reports of worsening symptoms with exercise, which brings up cardiac questions that have to be ruled out first.   [24:19] Dr. Dellon mentions some more atypical symptoms. An adult having pain in the upper abdomen could have EoE. In children, the symptoms could be anything in the GI tract. Some women might have atypical symptoms with less trouble swallowing.   [24:58] Some racial minorities may have those kinds of symptoms, as well. If you're not thinking of the condition, it's hard to make the diagnosis.   [25:08] Dr. Jensen notes that there are different cultural norms around expressing symptoms and dietary patterns, which may make it difficult to parse out a diagnosis.   [25:27] Ryan cites a past episode where access to a GI specialist played a role in diagnosing patients with EoE. Do white males have more EoE, or are their concerns just listened to more seriously?   [25:57] Ryan's parents were told when he was two that he was throwing up for attention. He believes that these days, he'd have a much easier time convincing a doctor to listen to him. From speaking to physicians, Ryan believes access is a wide issue in the field.   [26:23] Dr. Dellon tells of working with researchers at Mayo in Arizona and the Children's Hospital of Phoenix. They have a large population of Hispanic children with EoE, much larger than has been reported elsewhere. They're working on characterizing that.   [26:49] Dr. Dellon describes an experience with a visiting trainee from Mexico City, where there was not a lot of EoE reported. The trainee went back and looked at the biopsies there, and it turned out they were not performing biopsies on patients with dysphagia in Mexico City.   [27:13] When he looked at the patients who ended up getting biopsies, they found EoE in 10% of patients. That's similar to what's reported out of centers in the developed world. As people are thinking about it more, we will see more detection of it.   [27:30] Dr. Dellon believes those kinds of papers will be out in the next couple of months, to a year.   [27:36] Holly has had licensure in Arizona for about 11 years. She has had nine referrals recently of children with EoE from Arizona. Normally, it's been one or two that she met at a conference.   [28:00] Ryan asks about the research on patients not having their EoE treated pharmacologically. Some treat it with food avoidance and dietary therapy. Ryan notes that he can't have applesauce, as it is a trigger for his EoE.   [28:54] Dr. Jensen says that's one of the challenges in using the EHR data. That kind of information is only available to the researchers through free text. That's a limitation of the study, assessing the use of dietary elimination approaches.   [29:11] Holly says some of her patients have things listed as allergies that are food sensitivities. Ryan says it's helpful for the patients to have their food sensitivities listed along with their food allergies, but it makes records more difficult to parse for research.   [30:14] Dr. Dellon says they identify EoE by billing code, but the codes are not always used accurately. Natural Language Processing can train a computer system to find important phrases. Their collaborators working on the real-world data are using it.   [30:59] Dr. Dellon hopes that this will be a future direction for this research to find anything in the text related to diet elimination.   [31:32] Dr. Jensen says that older patients were less likely to seek medication therapy. She says it's probably for a couple of reasons. First, older patients may have been living with the disease for a long time and have had compensatory mechanisms in place.   [32:03] The other reason may be senescence or burnout of the disease, long-term. Patients may be less symptomatic as they get older. That's a question that remains to be answered for EoE. It has been seen in some other disease processes.   [32:32] Dr. Dellon says there's not much data specifically looking at EoE in the older population. Dr. Dellon did work years ago with another doctor, and they found that older patients had a better response to some treatments, particularly topical steroids.   [32:54] It wasn't clear whether it was a milder aspect of the disease, easier to treat, or because they were older and more responsible, taking their medicines as prescribed, and having a better response rate. It's the flip side of work in the pediatric population.   [33:16] There is an increasingly aging population with EoE. Young EoE patients will someday be over 65. Dr. Dellon hopes there will be a cure by that point, but it's an expanding population now.   [33:38] Dr. Jensen says only a few sites are contributing data, so they hope to add additional sites to the study. For some of the less common outcomes, they need a pretty large patient sample to ask some of those kinds of questions.   [33:55] They will continue to follow up on some of the work that this abstract touched on and try to understand some of these issues more deeply.   [34:06] Dr. Dellon mentions other work within the cohort. Using Natural Language Processing, they are looking at characterizing endoscopy information and reporting it without a manual review of reports and codes. You can't get that from billing data.   [34:29] Similarly, they are trying to classify patient severity by the Index of Severity with EoE, and layer that on looking at treatments and outcomes based on disease severity. Those are a couple of other directions where this cohort is going.   [34:43] Holly mentions that this is one of many research projects Dr. Jensen and Dr. Dellon have collaborated on together. They also collaborate through EGID Partners. Holly asks them to share a little bit about that.   [34:53] Dr. Jensen says EGID Partners is an online registry where individuals, caregivers, and parents of children affected with EGIDs can join.   [35:07] EGID Partners also needs people who don't live with an EGID to join, as controls. That gives the ability to compare those who are experiencing an EGID relative to those who aren't.   [35:22] When you join EGID Partners, they provide you with a set of questionnaires to complete. Periodically, they push out a few more questionnaires.   [35:33] EGID Partners has provided some really great information about patient experience and answered questions that patients want to know about, like joint pain and symptoms outside the GI tract.   [36:04] To date, there are close to 900 participants in the registry from all over the world. As it continues to grow, it will give the ability to look at the patient experience in different geographical areas.   [36:26] Dr. Dellon says we try to have it be interactive, because it is a collaboration with patients. The Steering Committee works with APFED and other patient advocacy groups from around the world.    [36:41] The EGID Partners website shows general patient locations anonymously. It shows the breakdown of adults with the condition and caregivers of children with the condition, the symptom distribution, and the treatment distribution.   [37:03] As papers get published and abstracts are presented, EGID Partners puts them on the website. Once someone joins, they can suggest a research idea. Many of the studies they have done have come from patient suggestions.   [37:20] If there's an interesting idea for a survey, EGID Partners can push out a survey to everybody in the group and answer questions relatively quickly.   [37:57] Dr. Dellon says a paper came out recently about telehealth. EoE care, in particular, is a good model for telehealth because it can expand access for patients who don't have providers in their area.   [38:22] EoE is a condition where care involves a lot of discussion but not a lot of need for physical exams and direct contact, so telehealth can make things very efficient.    [38:52] EGID Partners surveyed patients about telehealth. They thought it was efficient and saved time, and they had the same kind of interactions as in person. In general, in-state insurance covered it. Patients were happy to do those kinds of visits again.   [39:27] Holly says Dr. Furuta, herself, and others were published in the Gastroenterology journal in 2019 about starting to do telehealth because patients coming to the Children's Hospital of Colorado from out of state had no local access to feeding therapy.   [39:50] Holly went to the board, and they allowed her to get licensure in different states. She started with some of the most impacted patients in Texas and Florida in 2011 and 2012. They collected data. They published in 2019 about telehealth's positive impact.   [40:13] When 2020 rolled around, Holly had trained a bunch of people on how to do feeding therapy via telehealth. You have to do all kinds of things, like make yourself disappear, to keep the kids engaged and in their chairs!   [40:25] Now it is Holly's primary practice. She has licenses in nine states. She sees people all over the country. With her diagnosis, her physicians at Mass General have telehealth licensure in Maine. She gets to do telehealth with them instead of driving two hours.   [40:53] Dr. Jensen tells of two of the things they hope to do at EGID Partners. One is trying to understand more about reproductive health for patients with an EGID diagnosis. Only a few studies have looked at this question, and with very small samples.   [41:15] As more people register for EGID Partners, Dr. Jensen is hoping to be able to ask some questions related to reproductive health outcomes.   [41:27] The second goal is a survey suggested by the Student Advisory Committee, asking questions related to the burden of disease specific to the teen population.   [41:48] This diagnosis can hit that population particularly hard, at a time when they are trying to build and sustain friendships and are transitioning to adult care and moving away from home. This patient population has a unique perspective we wanted to hear.   [42:11] Dr. Jensen and Dr. Dellon work on all kinds of other projects, too.   [42:22] Dr. Dellon says they have done a lot of work on the early-life factors that may predispose to EoE. They are working on a large epidemiologic study to get some insight into early-life factors, including factors that can be measured in baby teeth.   [42:42] That's outside of EGID Partners. It's been ongoing, and they're getting close, maybe over the next couple of years, to having some results.   [43:03] Ryan says all of those projects sound so interesting. We need to have you guys back to dive into those results when you have something finalized.   [43:15] For our listeners who want to learn more about eosinophilic disorders, we encourage you to visit apfed.org and check out the links in the show notes below.   [43:22] If you're looking to find specialists who treat eosinophilic disorders, we encourage you to use APFED's Specialist Finder at apfed.org/specialist.   [43:31] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at apfed.org/connections.   [43:41] Ryan thanks Dr. Dellon and Dr. Jensen for joining us today. This was a fantastic conversation. Holly also thanks APFED's Education Partners GSK, Sanofi, Regeneron, and Takeda for supporting this episode.   Mentioned in This Episode: Evan S. Dellon, MD, MPH, Academic Gastroenterologist, University of North Carolina School of Medicine   Elizabeth T. Jensen, MPH, PhD, Epidemiologist, Wake Forest University School of Medicine, University of North Carolina at Chapel Hill   Predictors of Patients Receiving No Medication for Treatment of Eosinophilic Esophagitis in the United States: Data from the TARGET-EGIDS Cohort   Episode 15: Access to Specialty Care for Eosinophilic Esophagitis (EoE)   APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections apfed.org/research/clinical-trials   Education Partners: This episode of APFED's podcast is brought to you thanks to the support of GSK, Sanofi, Regeneron, and Takeda.   Tweetables:   "I've been working on eosinophilic gastrointestinal diseases for about 15 years. I started some of the early work around understanding possible risk factors for the development of disease. I've gone on to support lots of other research projects." — Elizabeth T. Jensen, MPH, PhD   "You can think of EoE as asthma of the esophagus or eczema of the esophagus, although in general, people don't grow out of EoE, like they might grow out of eczema or asthma. When people have it, it really is a long-term condition." — Evan S. Dellon, MD, MPH   "There are two general approaches to treating the underlying condition, … using medicines and/or eliminating foods from the diet that we think may trigger EoE. I should say, for a lot of people, EoE is a food-triggered allergic condition." — Evan S. Dellon, MD, MPH   "I didn't find it that surprising [that there are patients who had no treatment]. Some patients are relatively asymptomatic, and others are not interested in pursuing medications initially or are … still exploring dietary treatment options." — Elizabeth T. Jensen, MPH, PhD   "We have a bunch of studies now that look at how long people have symptoms before they're diagnosed. There's a wide range. Some people get symptoms and are diagnosed right away. Other people might have symptoms for 20 or 30 years." — Evan S. Dellon, MD, MPH   "EGID Partners is an online registry where individuals, caregivers, and parents of children affected with EGIDs can join. EGID Partners also needs people who don't live with an EGID to join, as controls." — Elizabeth T. Jensen, MPH, PhD

Application pour EV0360 : https://hlperformance.caRéférences :Hall, K. D., Farooqi, I. S., Friedman, J. M., et al. (2022). The energy balance model of obesity: beyond calories in, calories out. *American Journal of Clinical Nutrition*, 115(5), 1243–1254. https://doi.org/10.1093/ajcn/nqac031Mõttus, R., Realo, A., Allik, J., Ausmees, L., Henry, S., McCrae, R. R., & Vainik, U. (2024). Most people's life satisfaction matches their personality traits: True correlations in multitrait, multirater, multisample data. *Journal of Personality and Social Psychology*, 126(4), 676–693.Montesi, L., El Ghoch, M., Brodosi, L., Calugi, S., Marchesini, G., & Dalle Grave, R. (2016). Long-term weight loss maintenance for obesity: A multidisciplinary approach. *Diabetes, Metabolic Syndrome and Obesity*, 9, 37–46. https://doi.org/10.2147/DMSO.S89836Armon, G., Melamed, S., Shirom, A., Shapira, I., & Berliner, S. (2013). Personality traits and body weight measures: Concurrent and across-time associations. *European Journal of Personality*, 27(4), 398–408.Ryan, R. M., & Deci, E. L. (2000). Self-determination theory and the facilitation of intrinsic motivation, social development, and well-being. *American Psychologist*, 55(1), 68–78. https://doi.org/10.1037/0003-066X.55.1.68Mathews, A. (1990). Why worry? The cognitive function of anxiety. *Behaviour Research and Therapy*, 28(6), 455–468.

The US has no shortage of lidocaine patch television commercials. Topical lidocaine has a role for local, topical, minor aches and pains. What about lidocaine patches for post-op cesarean section pain? Is there data for that? A brand-new meta-analysis in AJOG-MFM (Nov 13, 2025) looks at this option. However, there has been 3 prior reviews on the same topic from 2019, 2022, and 2023. Do they all arrive at the same result? Listen in for details!1.     Smoker J, Cohen A, Rasouli MR, Schwenk ES. TransdermalLidocaine for Perioperative Pain: A Systematic Review of the Literature. Current Pain and Headache Reports.2019;23(12):89. doi:10.1007/s11916-019-0830-9.2.     Koo CH, Kim J, Na HS, Ryu JH, Shin HJ. TheEffect of Lidocaine Patch for Postoperative Pain: A Meta-Analysis of Randomized Controlled Trials. Journal of Clinical Anesthesia. 2022;81:110918.doi:10.1016/j.jclinane.2022.110918.3.     Wu X, Wei X, Jiang L, et al. Is Lidocaine PatchBeneficial for Postoperative Pain?: A Meta-Analysis of Randomized Clinical Trials. The Clinical Journal of Pain. 2023;39(9):484-490. doi:10.1097/AJP.00000000000011354.     Parisi, Nadia et al.Lidocaine patches aftercesarean delivery: a meta-analysis of randomized controlled trials. American Journal of Obstetrics & Gynecology MFM, Volume 0, Issue 0, 101832

Infowars And Other Sites Affected By MASSIVE Cloudflare Outage, House Votes To Release Epstein Files, Border Patrol Cleans Up Charlotte

On this episode of Managed Care Cast, Rachel A. Prusynski, DPT, PhD, an assistant professor at the University of Washington's School of Medicine, speaks with The American Journal of Managed Care® about her research published in the November 2025 issue. Her study, "Medicare Advantage Reimbursement Structures Impact Home Health Delivery and Outcomes," explores how home health care delivery and patient outcomes differ between 3 plan types: traditional Medicare, episodic Medicare Advantage, and per-visit Medicare Advantage. Throughout the conversation, Prusynski discusses what motivated the research, the study's key findings, and the broader implications for improving the quality and accessibility of future home health care.

Trump Throws Support Behind House GOP Vote To Release Epstein Files, Continues Attacking MTG As “Traitor” As MAGA Civil War Wages On

Political Establishment Continues Trying To Link Trump, Bannon To Epstein & Alex Jones Joins Transmission On One Year Anniversary Of Democrats Attempting To Shut Down Infowars

What does it actually mean to be "documented" or "undocumented" as a migrant to the USA? What's the lived reality like of existing somewhere in between the two, including under the category of "temporary protected status", or TPS, created by Congress in 1990 for people from countries deemed too unsafe to return to? UCLA sociologist and leading migration expert Cecilia Menjívar joins us to discuss her concept of "liminal legality". Elaborated in a 2006 paper following fieldwork through the 1990s with migrants from Central America, the term remains enduringly relevant in Trump's America - where the administration has moved to roll back TPS for people from countries such as Afghanistan, Venezuela and Syria. A conversation about precarity, lived experience, and policy - and a reminder that "creating a group of people whose rights are diminishing by the day" harms not only those individuals, but all of us.    **Recorded Sept 2025**   Suggested Reading: 'Behind the headlines: Temporary Protected Status', a factsheet from the International Rescue Committee, with links to the latest developments on attempts to end protections for people from Venezuela, Afghanistan, Cameroon, Nepal, Honduras, Nicaragua and Syria '1990: Temporary Protection Status (TPS)' - a research guide from the Library of Congress, A Latinx Resource Guide: Civil Rights Cases and Events in the United States. **including a useful timeline** 'Liminal Legality: Salvadoran and Guatemalan Immigrants' Lives in the United States'  (January 2006) by Cecilia Menjívar in the American Journal of Sociology 'Effects of SB 1070 on Children', by Carlos Santos, Cecilia Menjívar, Erin Godfrey, Pp. 79-92 in Latino Politics and Arizona's Immigration Law SB 1070, edited by Lisa Magaña and Erik Lee. New York: Springer 2013 'Temporary Protected Status for Central American Immigrants: Advancing Immigrant Integration Despite Its Uncertainty' (2020) a policy report by Cecilia Menjívar 'The Ritual Process: Structure and Anti-Structure' (1969) by Victor Turner Update, September 2025: "Judge rules ending protections for Venezuelan and Haitian migrants is unlawful" (BBC News) The work of the National Temporary Protected Status Alliance On the Reagan-backed wars in the 1980s: 'Central America, 1981–1993' from the US Office of the Historian ** An updated TPS factsheet on the status of various designations, from the National Immigration Forum. This includes updates re: Haiti, Venezuela and Syria **   Active listening questions: What did Cecilia mean by "liminal legality" when she coined the term in her 2006 paper? And how is it manifest today?  How might geopolitics play a role in whether an individual with a given nationality is labelled as a refugees or asylum seeker? Why is it important to look beyond labour market experience when we consider the experience of people labelled as migrants? What and what stands to gain when minoritised or vulnerable people are rendered "impermanent" or "temporary"? What does Cecilia's approach show about the value of using sociological research and analysis to complicate seemingly neat binaries?  Cecilia talks about how the precaritisation of some people's migration status "reverberates across US society", impacting us all. What does she mean by this and how does it connect with what Michaela speaks of as "de-migrantising" migration research? 

Newsom's Ex-Chief Of Staff Arrested, Accused Of Stealing $225K! Trump Signs Funding Bill To End Longest Government Shutdown

Well, from time to time we cover RANDOM tidbits of information which cover RANDOM questions and/or RANDOM patient care issues that we encounter. In this episode we will cover one OB issue related to recurrent pregnancy loss, one GYN issue related to unilateral breast swelling in a patient with SLE, and one RANDOM life perspective response from a mock interview that I participated in for a residency candidate. Listen in fordetails!1.     Viviana DO; Giugni, Claudio Schenone MD; Ros, Stephanie T. MD, MSCI. Factor V and recurrent pregnancy loss: de Assis, Evaluation of Recurrent Pregnancy Loss. Obstetrics & Gynecology 143(5):p 645-659, May 2024. | DOI: 10.1097/AOG.0000000000005498Unilateral Breast Swelling with SLE: 2.     Voizard B, Lalonde L, Sanchez LM, et al. LupusMastitis as a First Manifestation of Systemic Disease: About Two Cases With a Review of the Literature. European Journal of Radiology. 2017;92:124-131. doi:10.1016/j.ejrad.2017.04.023.3.     Kinonen C, Gattuso P, Reddy VB. Lupus Mastitis:An Uncommon Complication of Systemic or Discoid Lupus. The American Journal of Surgical Pathology. 2010;34(6):901-6. doi:10.1097/PAS.0b013e3181da00fb.4.      Summers TA, Lehman MB, Barner R, Royer MC. Lupus Mastitis: A Clinicopathologic Review and Addition of a Case. Advances in Anatomic Pathology.2009;16(1):56-61. doi:10.1097/PAP.0b013e3181915ff7.5.     Jiménez-Antón A, Jiménez-Gallo D,Millán-Cayetano JF, Navarro-Navarro I, Linares-Barrios M. Unilateral Lupus Mastitis.Lupus. 2023;32(3):438-440. doi:10.1177/09612033221151011.STRONG COFFEE PROMO: 20% Off Strong Coffee Company https://strongcoffeecompany.com/discount/CHAPANOSPINOBG

House Set To End Schumer Shutdown, UK Stops Sharing Intelligence With US, Massive Solar Flare Could Disrupt Power Grid

Dems Walk Away Empty Handed After Senate Votes To End Longest-Ever Govt Shutdown, Leftist Base  Demands ‘Ruthlessly Pragmatic' Approach to Counter Trump! Newsom Campaigns In Texas, Emerges As Top Dem Pick

Lecture summary: Over centuries and across continents, authoritarian governments have demonstrated a large appetite for international cooperation to target political opponents across borders. As the world's premier body for international police cooperation, Interpol is not supposed to facilitate this kind of transnational repression -- and yet, in recent years, there is growing concern that authoritarian governments are abusing Interpol's tools. Interpol has taken meaningful steps to curb such abuse, but the durability of those protections is in doubt given the rising influence of authoritarian governments in that organization. The looming question is at what point universal multilateral cooperation with respect to law enforcement might cease to be viable.Kristina Daugirdas is the Francis A. Allen Collegiate Professor of Law at the University of Michigan Law School. She teaches and writes primarily in the fields of international law and institutions.Her scholarship currently focuses on international organizations, accountability mechanisms, and the ongoing evolution of the international legal system. She is a member of the editorial board of the International Organizations Law Review and the State Department's Advisory Committee on International Law. She also serves as an adviser to the American Law Institute's Restatement (Fourth) of Foreign Relations Law.In 2016–2017, Daugirdas was a visiting fellow at the Graduate Institute of International and Development Studies in Geneva and served as a consultant on public international law issues for the World Intellectual Property Organization. From 2014 to 2017, she co-authored the Contemporary Practice of the United States Relating to International Law: A section of the American Journal of International Law. In 2014, she was awarded the Francis Deák Prize for an outstanding article published in the American Journal of International Law by a younger author.Daugirdas has taken on significant leadership roles at the law school, including serving as Associate Dean for Academic Programming from 2021 to 2024. She also led a subcommittee of the Advisory Committee on the University of Michigan Principles on Diversity of Thought and Freedom of Expression.Prior to entering academia, Daugirdas was an attorney-adviser at the State Department's Office of the Legal Adviser, receiving multiple honors for her service. As an attorney-adviser, she provided guidance on the negotiation and implementation of UN Security Council sanctions and amicus participation by the US government in lawsuits with foreign policy implications.Chair: Prof Fernando Lusa BordinThis lecture was given on 7 November 2025 and is part of the Friday Lunchtime Lecture series at the Lauterpacht Centre.

Lecture summary: Over centuries and across continents, authoritarian governments have demonstrated a large appetite for international cooperation to target political opponents across borders. As the world's premier body for international police cooperation, Interpol is not supposed to facilitate this kind of transnational repression -- and yet, in recent years, there is growing concern that authoritarian governments are abusing Interpol's tools. Interpol has taken meaningful steps to curb such abuse, but the durability of those protections is in doubt given the rising influence of authoritarian governments in that organization. The looming question is at what point universal multilateral cooperation with respect to law enforcement might cease to be viable.Kristina Daugirdas is the Francis A. Allen Collegiate Professor of Law at the University of Michigan Law School. She teaches and writes primarily in the fields of international law and institutions.Her scholarship currently focuses on international organizations, accountability mechanisms, and the ongoing evolution of the international legal system. She is a member of the editorial board of the International Organizations Law Review and the State Department's Advisory Committee on International Law. She also serves as an adviser to the American Law Institute's Restatement (Fourth) of Foreign Relations Law.In 2016–2017, Daugirdas was a visiting fellow at the Graduate Institute of International and Development Studies in Geneva and served as a consultant on public international law issues for the World Intellectual Property Organization. From 2014 to 2017, she co-authored the Contemporary Practice of the United States Relating to International Law: A section of the American Journal of International Law. In 2014, she was awarded the Francis Deák Prize for an outstanding article published in the American Journal of International Law by a younger author.Daugirdas has taken on significant leadership roles at the law school, including serving as Associate Dean for Academic Programming from 2021 to 2024. She also led a subcommittee of the Advisory Committee on the University of Michigan Principles on Diversity of Thought and Freedom of Expression.Prior to entering academia, Daugirdas was an attorney-adviser at the State Department's Office of the Legal Adviser, receiving multiple honors for her service. As an attorney-adviser, she provided guidance on the negotiation and implementation of UN Security Council sanctions and amicus participation by the US government in lawsuits with foreign policy implications.Chair: Prof Fernando Lusa BordinThis lecture was given on 7 November 2025 and is part of the Friday Lunchtime Lecture series at the Lauterpacht Centre.

Senate Dems Break With Schumer, Advance Plan To End Record-Breaking Gov't Shutdown 

The ACOG acknowledges that maternal obesity affects labor curves and recommends allowing more time for cervical dilation before diagnosing labor arrest in obese patients. This approach aims to avoid unnecessary interventions, such as premature cesarean delivery, which may occur if standard labor curves are strictly applied to obese women. In this episode, we will review a new study from the AJOG (08 Nov 2025) which describes labor progression and duration according to maternal body mass index, validating the need (possibly) for a BMI -based labor curve. Has there been advocates of a BMI-based labor curve? Listen in for details.1. Edwards, Sara et al. Characterizing Labor Progression and Duration According to Maternal Body Mass Index. American Journal of Obstetrics & Gynecology, Volume 0, Issue 02. Lundborg L, Liu X, Åberg K, et al. Association of Body Mass Index and Maternal Age With First Stage Duration of Labour. Scientific Reports. 2021;11(1):13843. doi:10.1038/s41598-021-93217-5.3. Kominiarek MA, Zhang J, Vanveldhuisen P, et al. Contemporary Labor Patterns: The Impact of Maternal Body Mass Index. American Journal of Obstetrics and Gynecology. 2011;205(3):244.e1-8. doi:10.1016/j.ajog.2011.06.014.4. Norman SM, Tuuli MG, Odibo AO, et al. The Effects of Obesity on the First Stage of Labor.Obstetrics and Gynecology. 2012;120(1):130-5. doi:10.1097/AOG.0b013e318259589c.

MOPs & MOEs is powered by TrainHeroic, the best coaching app on the planet. ⁠⁠⁠Click here to get 14 days FREE and a consult with the coaches at TrainHeroic to help you get your coaching business rolling on TrainHeroic. ⁠⁠⁠ MOPs & MOEs delivers our training through ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TrainHeroic and you can ⁠⁠⁠get your first 7 days of training with us FREE by clicking here.⁠⁠⁠To continue the conversation, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠join our Discord!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ We have experts standing by to answer your questions.Dr. Rich Willy is a new Associate Professor in the PhD program in the School of Health and Rehabilitation Sciences at The Ohio State University. He holds a PhD in Biomechanics and Movement Science from the University of Delaware and a Master's of Physical Therapy from Ohio University. He is a licensed physical therapist with over two decades of clinical and academic experience. His research focuses on the biomechanics of running-related injuries, bone stress injuries, and rehabilitation strategies for tactical and athletic populations.Dr. Willy has authored more than 80 peer-reviewed publications and book chapters, and his work has been featured in high-impact journals such as British Journal of Sports Medicine, Journal of Orthopaedic & Sports Physical Therapy, and American Journal of Sports Medicine. Dr. Willy contributes to clinical practice guidelines for patellofemoral pain and running injuries. He is a frequently invited speaker at national and international conferences, including symposia for the US and International Olympic Committees, NBA teams, and sports medicine meetings.His research has been supported by the Department of Defense and APTA Orthopaedics, among others. Current projects include optimizing load carriage biomechanics, developing sex-specific training interventions, and advancing wearable technologies for injury prevention and rehabilitation.He and his wife also run Montana Running Lab, a hugely valuable resource curating the best clinical evidence for athletes and rehab professionals. We highly recommend their instagram as an evidence based source of information. We'll talk a bit about some of the resources available there at the end of this episode.

 Bannon Warns MAGA Loyalists Will Be Jailed If GOP Loses Midterms & 2028 Presidential Election, Thousands More Flights Canceled Amid Gov't Shutdown, Muslims Declare New York An Islamic City & Much More

Russia Closing In On Major Ukrainian City, Putin Mulls Resuming Nuclear Tests As POTUS Pushes For Friday Peace Talks

Mamdani Secures NYC Mayoral Victory, Texas Passes 17 Constitutional Amendments & All US Flights Could Be Grounded By Next Week

Air Traffic Controller Shortage Causes Travel Nightmare Amid Ongoing Schumer Shutdown

Liz Seegert is an award-winning, independent journalist. Liz has written about health for more than 30 years. Her main beats include aging, women's health, social determinants of health, and health policy. Liz's articles have appeared in dozens of national and local media outlets including Scientific American, TIME, The American Journal of Nursing, and Web MD/Medscape. […] The post Narrative Journalism: Stories to Make Points Clear and Compelling (HLOL #265) appeared first on Health Literacy Out Loud Podcast.

Description:  Hosts Roz and Dr. Sanchez-Fueyo are joined by Christie Rampersad to discuss the key articles of the November issue of the American Journal of Transplantation. Christie Rampersad is clinical associate, in the Division of Nephrology at the University of Toronto in the Ajmera Transplant Centre [03:45] The early impacts of an attempt to standardize kidney procurement biopsy practices [13:40] The current state of simultaneous heart-liver transplantation in the United States [20:11] Engaging patients in organ transplant listing meetings: A survey study [37:32] Single-cell transcriptional landscape of liver transplant rejection reveals tissue persistence of clonally expanded, treatment-resistant T cells [45:32] Infectious disease surveillance and management in clinical xenotransplantation: Experience with the first human porcine kidney transplant

Trump Calls on Senate to Initiate “Nuclear Option” and Get Rid of Filibuster As SNAP Benefits Set to Run Out! Plus, US Poised to Strike Military Targets In Venezuela

Improving+Healthcare+for+Coptic+Egyptian+MigrantsOpening cultural doors: Providing culturally sensitive healthcare to Arab American and American Muslim patients - American Journal of Obstetrics & GynecologyCultural Competence in the Care of Muslim Patients and Their Families - StatPearls - NCBI Bookshelf No content or comments made in any TIPQC Healthy Mom Healthy Baby Podcast is intended to be comprehensive or medical advice. Neither healthcare providers nor patients should rely on TIPQC's Podcasts in determining the best practices for any particular patient. Additionally, standards and practices in medicine change as new information and data become available and the individual medical professional should consult a variety of sources in making clinical decisions for individual patients. TIPQC undertakes no duty to update or revise any particular Podcast. It is the responsibility of the treating physician or health care professional, relying on independent experience and knowledge of the patient, to determine appropriate treatment.

Trump Resumes US Nuclear Tests After 33-Year Hiatus, Minutes Before Meeting With China's Xi Jinping & Days After Russia Tested High-Tech Nukes

Food Stamps Run Out In Days, Triggering Massive Unrest Intentionally Unleashed By Democrats' Schumer Shutdown

On this episode of the Hayek Program Podcast, Nina Bandelj delivers a keynote lecture at the 2023 Markets & Society conference on the social life of money for children. Drawing on research about what she calls the “parenting economy,” she shows that parents increasingly treat children as human capital investments, using savings plans, loans, and educational spending to secure their futures. Bandelj argues that the financialization of family life reflects parental pressures and social inequality, calling for children to be seen as a shared public responsibility rather than private investments.Dr. Nina Bandelj is Chancellor's Professor in the Department of Sociology at the University of California, Irvine and the President of the Sociological Research Association. Her articles have been published in top discipline and specialty journals such as the American Sociological Review, American Journal of Sociology, Social Forces, Theory and Society, and Socio-Economic Review. She has published various books, including Overinvested: The Emotional Economy of Modern Parenting (Princeton University Press, forthcoming), Money Talks: Explaining How Money Really Works (Princeton University Press, 2017) coauthored with Frederick Wherry and Viviana Zelizer), and Socialism Vanquished, Socialism Challenged: Eastern Europe and China, 1989-2009 (Oxford university Press, 2012) coedited with Dorothy Solinger.**This lecture was recorded October 22, 2023 at the second annual Markets & Society conference.If you like the show, please subscribe, leave a 5-star review, and tell others about the show! We're available on Apple Podcasts, Spotify, Amazon Music, and wherever you get your podcasts.Check out our other podcast from the Hayek Program! Virtual Sentiments is a podcast in which political theorist Kristen Collins interviews scholars and practitioners grappling with pressing problems in political economy with an eye to the past. Subscribe today!Follow the Hayek Program on Twitter: @HayekProgramFollow the Mercatus Center on Twitter: @mercatusCC Music: Twisterium

Venezuela Says It Captured CIA Group Planning False Flag Attack, Maduro Condemns US “Military Provocation” As White House Considers Air Force Strikes

In this episode of the Glowing Older podcast, host Nancy Griffin interviews Dr. Kenneth Pelletier, a clinical professor of medicine and psychiatry at UCSF, about the science of longevity and the role of epigenetics. Dr. Pelletier shares insights into the importance of healthspan over lifespan, and the impact of diet, stress, exercise, and social support on longevity. He also discusses the potential and limitations of biohacking and the growing field of integrative medicine. About Dr. Pelletier Kenneth R. Pelletier, PhD, MD is a Clinical Professor of Medicine, Department of Medicine; Department of Family and Community Medicine; and Department of Psychiatry at the University of California School of Medicine (UCSF) in San Francisco; and a Clinical Professor of Medicine in the Department of Medicine and Department Family and Community Medicine at the University of Arizona School of Medicine in Tucson. At the present time, Dr. Pelletier is a medical and business consultant to the US Department of Health and Human Services, the World Health Organization (WHO), the National Business Group on Health, the Federation of State Medical Boards, the Wild Dolphin Project, and major corporations including Cisco, IBM, American Airlines, Prudential, Dow, Disney, Ford, Mercer, Merck, Pepsico, Ford, Pfizer, Walgreens, NASA, Microsoft ENCARTA, Blue Cross/Blue Shield, United Healthcare, Health Net, the Pasteur Institute of Lille, France, the Alpha Group of Mexico, and the Singapore Ministry of Health. He also serves on the boards of the Rancho la Puerta (Mexico), Nova Institute, Fries Foundation, American Institute of Stress (AIS), American Journal of Health Promotion (AJHP), as a Founding Board Member of the American Board of Integrative Medicine (ABOIM), and as a peer reviewer for the Journal of the American Medical Association (JAMA), the Journal of Occupational and Environmental Medicine (JOEM), Annals of Internal Medicine, Health Affairs, and webMD.  Dr. Pelletier is listed in Who's Who in America and in Who's Who in the World. He has been featured on ABC World News, the Today program, Good Morning America, Dr Oz, the CBS Evening News, 48 Hours, the McNeil-Lehrer Newshour, CNN, FOX News, and CBS Sunday Morning.Dr. Pelletier is the author of 15 major books including the international bestseller Mind as Healer, Mind as Slayer; Holistic Medicine: From Stress to Optimum Health; Longevity: Fulfilling Our Biological Potential; Healthy People in Unhealthy Places; Stress and Fitness at Work; Sound Mind – Sound Body: A New Model for Lifelong Health; The Best Alternative Medicine: What Works? What Does Not?; Stress Free for Good: Ten Scientifically Proven Life Skills for Health and Happiness; New Medicine: How to Integrate Conventional and Alternative Medicine for the Safest and Most Effective Treatment and Change Your Genes – Change Your Life: Creating Optimal Health with the New Science ofEpigenetics.Key TakeawaysEpigenetics is a relatively new science, developed in the last 15 years. Epigenetics are all of the influences that determine our health, wellbeing, and life expectancy after the sperm and ovum unite. Epigenetics plays a crucial role in determining health and life expectancy – 95 % of health, illness, and life expectancy are due to factors other than our genes. The role of diet, stress, physical activity and social support significantly influence genetic expression.There are no longitudinal studies for biohacking. Don'tgo into the periphery and engage in questionable practices. Sort hope from hype.Equal criteria for evaluating the outcomes of alternative and conventional medicine must be applied; both should be held to the same rigorous scientific standards to ensure their acceptability and effectiveness.

A reading of articles and features from the October/November 2025 Issue of the Polish American Journal

Russia Tests High-Tech Nukes While Trump Asks Xi For Help Ending Ukraine War & USA Prepares To Strike Venezuela

This week on The Sausage of Science, Chris and Cara talk with Dr. Josh Brahinsky, a researcher in the Transcultural Psychiatry Department at McGill University and the Department of Religious Studies at Stanford University, whose work sits at the intersection of anthropology, psychology, and neuroscience. Josh explores how contemplative practices like prayer and meditation shape sensory experience, perception, and emotion, focusing especially on the embodied and affective dimensions of charismatic evangelical worship. With a background that bridges the humanities and sciences, a PhD in the History of Consciousness from UCSC, and a postdoctoral fellowship in Anthropology at Stanford, Josh brings a truly interdisciplinary lens to understanding what happens when people reach for the divine, and how those moments transform the body and mind alike. ------------------------------ Find the book discussed in this episode: Tongues of Fire: How Charismatic Prayer Changes Evangelical Brains and Mobilizes Spirit-Filled Activism www.bloomsbury.com/us/tongues-of-f…-9798881804992/ Find the Article: Brahinsky, J., Mago, J., Miller, M., Catherine, S., & Lifshitz, M. (2024). The Spiral of Attention, Arousal, and Release: A Comparative Phenomenology of Jhāna Meditation and Speaking in Tongues. American Journal of Human Biology, 36(12), e24189. doi.org/10.1002/ajhb.24189 ------------------------------ Contact Dr. Brahinsky: jbrahins@gmail.com ------------------------------ Contact the Sausage of Science Podcast and Human Biology Association: Facebook: facebook.com/groups/humanbiologyassociation/, Website: humbio.org, Twitter: @HumBioAssoc Chris Lynn, Host Website: cdlynn.people.ua.edu/, E-mail: cdlynn@ua.edu, Twitter:@Chris_Ly Cara Ocobock, Host Website: sites.nd.edu/cara-ocobock/, Email:cocobock@nd.edu, Twitter:@CaraOcobock Cristina Gildee, SoS Co-Producer, HBA Fellow Website: cristinagildee.org, E-mail: cgildee@uw.edu,

Bondi Tells Pelosi to “Preserve Her Emails” After She Called For ICE Agents To Be Arrested

Gov't Shutdown Enters Day 23 As Democrats Attempt To Implode Trump Economy, Launch Domestic Uprising & Blame MAGA For It All

Dr. Ryan Sultan is a Board Certified Adult and Child Psychiatrist, researcher and Assistant Professor of Clinical Psychiatry at Columbia University Irving Medical Center. He is also in private practice with expertise in the evaluation and treatment of ADHD. One in six American boys is now diagnosed with ADHD. In France, it's one in 200. American children are diagnosed with ADHD at rates 30 times higher than other Western nations. We consume 80% of the world's ADHD stimulants despite being 4% of the population.There's no blood test, no brain scan, no biological evidence this "disorder" actually exists - just subjective checklists and lines of questioning. In this essential episode, Dr. McFillin challenges the validity and reliability of ADHD diagnosis, and what unfolds is a stunning revelation about how 7 million children ended up on amphetamines. References:MTA Study (Multimodal Treatment Study of ADHD):MTA Cooperative Group. (1999). A 14-month randomized clinical trial of treatment strategies for ADHD. Archives of General Psychiatry, 56(12), 1073-1086.Molina, B. S., et al. (2009). MTA at 8 years: Prospective follow-up of children treated for combined-type ADHD. Journal of the American Academy of Child & Adolescent Psychiatry, 48(5), 484-500.Key finding: No difference in outcomes between medicated and non-medicated groups at 3-year and 8-year follow-upsCDC ADHD Statistics:CDC. (2022). Data and Statistics About ADHD. Centers for Disease Control and Prevention.7.1 million US children diagnosed with ADHD (11.4% of all children)15.5% of boys diagnosed vs. 7.5% of girls1 in 6 boys aged 4-17 diagnosed with ADHD3.3 million children aged 3-17 currently on ADHD medicationRacial Disparities in Diagnosis of ADHDDSM-5 Field Trial Reliability:Regier, D. A., et al. (2013). DSM-5 field trials in the United States and Canada. American Journal of Psychiatry, 170(1), 59-70.ADHD kappa reliability: 0.61 (research settings) to 0.35 (clinical practice)Financial Data:ADHD medication market: $19.8 billion (2024, Market Research Reports)10-fold increase in stimulant prescriptions: 1990-2024 (DEA production quotas) Faraone, S.V., Sergeant, J., Gillberg, C., & Biederman, J. (2003). The worldwide prevalence of ADHD: Is it an American condition? World Psychiatry, 2(2), 104-113.Funded by Johnson & Johnson (pharmaceutical company)Co-authored by Joseph Biederman (who later had to admit taking $1.6 million from drug companies without disclosure)What This Article Inadvertently Reveals:The Diagnosis Shopping Game: The article admits that using DSM-IV criteria produces the "highest prevalence rates" compared to other diagnostic systems. Translation: American psychiatry created diagnostic criteria that captures the most kids. This isn't discovering disease - it's widening the net.The 20-Fold Difference They Can't Explain: The article acknowledges a "20-fold greater prevalence of childhood hyperactivity in North America compared with England" in 1970s studies. Their explanation? Different diagnostic practices, not different children. So they're admitting the "disease" depends entirely on who's doing the diagnosing.The Admission Hidden in Plain Sight: The authors state that differences in prevalence "reflect differences in diagnostic practice rather than true differences in behavior." They're literally admitting ADHD prevalence is about diagnostic opinion, not biological reality.Even establishment researchers like Faraone admit that ADHD prevalence varies 20-fold based on diagnostic criteria used, not actual differences in children's behavior. They acknowledge it's diagnostic practice, not disease prevalence, that creates these massive variations. This 2003 paper proves psychiatry has known for decades that ADHD rates are artificially inflated by American diagnostic criteria.The Irony: This paper, trying to prove ADHD is universal, actually proves it's a diagnostic construct that changes based on which manual you use. That's not how real diseases work. Visit Center for Integrated Behavioral HealthDr. Roger McFillin / Radically Genuine WebsiteYouTube @RadicallyGenuineDr. Roger McFillin (@DrMcFillin) / XSubstack | Radically Genuine | Dr. Roger McFillinInstagram @radicallygenuineContact Radically GenuineConscious Clinician CollectivePLEASE SUPPORT OUR PARTNERS15% Off Pure Spectrum CBD (Code: RadicallyGenuine)10% off Lovetuner click here

Feds Face Off With Antifa Outside Portland ICE Facility As Local Police Continue Protecting Commies Instead Of Federal Agents

Democrat Chicago Judge Rules ICE Agents Can Be Arrested For Apprehending Illegals

A study published in the American Journal of Clinical Nutrition showed that eating two eggs daily lowered LDL cholesterol, while high saturated fat diets raised it Researchers found cholesterol from eggs did not raise LDL, but saturated fat from foods like bacon and sausage did, showing food context makes a major difference Eggs provide cholesterol without overloading the liver, allowing it to clear LDL efficiently and preventing artery buildup that increases heart disease and stroke risk Weekly egg intake reduced heart disease deaths by 29% and all-cause mortality by 17% in older adults, highlighting the importance of moderation for protective benefits Choosing pastured eggs, avoiding vegetable oils, and pairing eggs with nutrient-rich whole foods further boost benefits while minimizing harmful omega-6 linoleic acid (LA) intake

Trump Warns Zelensky To Accept Russia's Terms Or Be Destroyed Ahead Of Budapest Peace Summit Meeting With Putin

 US Special Ops & B-52s Train Near Venezuela, Trump Threatens American Military Action In Gaza As Dems Activate Leftist Mob For Civil Unrest

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These diseases - West Nile Virus, Lyme disease, and Rocky Mountain Spotted Fever - are named for the places where outbreaks happened. But they're also all things you get from being bitten by mosquitoes or ticks. Research: Balasubramanian, Chandana. “Rocky Mountain Spotted Fever (RMSF): The Deadly Tick-borne Disease That Inspired a Hit Movie.” Gideon. 9/1/2022. https://www.gideononline.com/blogs/rocky-mountain-spotted-fever/ Barbour AG, Benach JL2019.Discovery of the Lyme Disease Agent. mBio10:10.1128/mbio.02166-19.https://doi.org/10.1128/mbio.02166-19 Bay Area Lyme Foundation. “History of Lyme Disease.” https://www.bayarealyme.org/about-lyme/history-lyme-disease/ Caccone, Adalgisa. “Ancient History of Lyme Disease in North America Revealed with Bacterial Genomes.” Yale School of Medicine. 8/28/2017. https://medicine.yale.edu/news-article/ancient-history-of-lyme-disease-in-north-america-revealed-with-bacterial-genomes/ Chowning, William M. “Studies in Pyroplasmosis Hominis.("Spotted Fever" or "Tick Fever" of the Rocky Mountains.).” The Journal of Infectious Diseases. 1/2/1904. https://archive.org/details/jstor-30071629/page/n29/mode/1up Elbaum-Garfinkle, Shana. “Close to home: a history of Yale and Lyme disease.” The Yale journal of biology and medicine vol. 84,2 (2011): 103-8. Farris, Debbie. “Lyme disease older than human race.” Oregon State University. 5/29/2014. https://science.oregonstate.edu/IMPACT/2014/05/lyme-disease-older-than-human-race Galef, Julia. “Iceman Was a Medical Mess.” Science. 2/29/2012. https://www.science.org/content/article/iceman-was-medical-mess Gould, Carolyn V. “Combating West Nile Virus Disease — Time to Revisit Vaccination.” New England Journal of Medicine. Vol. 388, No. 18. 4/29/2023. https://www.nejm.org/doi/full/10.1056/NEJMp2301816 Harmon, Jim. “Harmon’s Histories: Montana’s Early Tick Fever Research Drew Protests, Violence.” Missoula Current. 7/20/2020. https://missoulacurrent.com/ticks/ Hayes, Curtis G. “West Nile Virus: Uganda, 1937, to New York City, 1999.” From West Nile Virus: Detection, Surveillance, and Control. New York : New York Academy of Sciences. 2001. https://archive.org/details/westnilevirusdet0951unse/ Jannotta, Sepp. “Robert Cooley.” Montana State University. 10/12/2012. https://www.montana.edu/news/mountainsandminds/article.html?id=11471 Johnston, B L, and J M Conly. “West Nile virus - where did it come from and where might it go?.” The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses vol. 11,4 (2000): 175-8. doi:10.1155/2000/856598 Lloyd, Douglas S. “Circular Letter #12 -32.” 8/3/1976. https://portal.ct.gov/-/media/departments-and-agencies/dph/dph/infectious_diseases/lyme/1976circularletterpdf.pdf Mahajan, Vikram K. “Lyme Disease: An Overview.” Indian dermatology online journal vol. 14,5 594-604. 23 Feb. 2023, doi:10.4103/idoj.idoj_418_22 MedLine Plus. “West Nile virus infection.” https://medlineplus.gov/ency/article/007186.htm National Institute of Allergy and Infectious Disease. “History of Rocky Mountain Labs (RML).” 8/16/2023. https://www.niaid.nih.gov/about/rocky-mountain-history National Institute of Allergy and Infectious Disease. “Rocky Mountain Spotted Fever.” https://www.niaid.nih.gov/diseases-conditions/rocky-mountain-spotted-fever Rensberger, Boyce. “A New Type of Arthritis Found in Lyme.” New York Times. 7/18/1976. https://www.nytimes.com/1976/07/18/archives/a-new-type-of-arthritis-found-in-lyme-new-form-of-arthritis-is.html?login=smartlock&auth=login-smartlock Rucker, William Colby. “Rocky Mountain Spotted Fever.” Washington: Government Printing Office. 1912. https://archive.org/details/101688739.nlm.nih.gov/page/ Sejvar, James J. “West Nile virus: an historical overview.” Ochsner journal vol. 5,3 (2003): 6-10. https://pmc.ncbi.nlm.nih.gov/articles/PMC3111838/ Smithburn, K.C. et al. “A Neurotropic Virus Isolated from the Blood of a Native of Uganda.” The American Journal of Tropical Medicine and Hygiene. Volume s1-20: Issue 4. 1940. Steere, Allen C et al. “The emergence of Lyme disease.” The Journal of clinical investigation vol. 113,8 (2004): 1093-101. doi:10.1172/JCI21681 Steere, Allen C. et al. “Historical Perspectives.” Zbl. Bakt. Hyg. A 263, 3-6 (1986 ). https://pdf.sciencedirectassets.com/281837/1-s2.0-S0176672486X80912/1-s2.0-S0176672486800931/main.pdf World Health Organization. “West Nile Virus.” 10/3/2017. https://www.who.int/news-room/fact-sheets/detail/west-nile-virus Xiao, Y., Beare, P.A., Best, S.M. et al. Genetic sequencing of a 1944 Rocky Mountain spotted fever vaccine. Sci Rep 13, 4687 (2023). https://doi.org/10.1038/s41598-023-31894-0 See omnystudio.com/listener for privacy information.