Podcasts about moestrup

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.10.17.512526v1?rss=1 Authors: Ferreira, S. A., Li, C., Klaestrup, I. H., Toft, G. U., Betzer, C., Svedsen, P., Jensen, P. H., Luo, Y., Etzerodt, A., Moestrup, S. K., Romero-Ramos, M. Abstract: The aggregation of alpha-synuclein (-syn) and immune activation are both pathological events related to the neurodegenerative process in Parkinsons disease (PD). The PD-associated immune response involves both brain and peripheral immune cells, although little is known about the immune proteins relevant for such response. CD163 is a scavenger receptor specifically expressed in the monocytic lineage, but normally not in microglia. Therefore, the presence of CD163 positive cells into the brain in PD rodent models and in PD patients suggest a monocytic infiltration or otherwise ectopic CD163 expression. In addition, changes in CD163 expression profiles observed in PD patients might indicate a role for CD163-expressing cells in the disease. To elucidate the relevance of the CD163 receptor in the -syn-induced immune events in PD and associated degeneration we injected murine -syn pre-formed fibrils (PFF), or monomeric -syn into the striatum of CD163 knockout (KO) mice and wild-type (WT) littermates. Injection of -syn PFF in CD163KO females led to impaired early immune responses as revealed by the lack of ability to upregulate MHCII, CD68, GFAP, and promote CD4 and CD8 T cell infiltration after -syn PFF injection. An early and long-lasting sensorimotor impairment was observed in -syn PFF CD163KO males but not in the females. Transcriptomic analysis revealed that CD163 deletion induced phenotypic changes of macrophages and microglia in the brain that potentially impact the motor behavior and neuronal health induced by -syn in a sex-dependent manner. After 6 months, CD163KO females showed an exacerbated immune response and -syn pathology associated with autophagic defects, which ultimately led to increased dopaminergic neurodegeneration. Overall, our results support a novel sex-dimorphic neuroprotective role for CD163 in the -syn-induced neuropathology and immune response. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Dette femte afsnit i rækken af LYT på BogForum 2019 er et interview med Mette Moestrup fra Litteratursidens stand, hvor LYTs Maria Louise Elgård Rasmussen bød på æbler og fulgtes med Moestrup tilbage til det gamle Grækenland og videre helt ud til solsystemets grænse på den anden side af Pluto. Interviewet omhandler Mette Moestrups "Til den smukkeste" (2019), der som eneste digtsamling var nomineret til Læsernes Bogpris 2020. 

Introduktion til LYTs minisæson med udsendelser fra BogForum 2019. Fra fredagen kan du høre interviews og samtaler med: Lea Marie Løppenthin, Knud Brix fra hedengangne Radio24Syvs Poesibogen samt et interview fra Turbines stand ml. Thomas Boberg og Martin Glaz Serup. Lørdagen byder på interviews og samtaler med: Mette Moestrup og Pia Juul. Om søndagen var det Asger Schnack, Søren Fauth og Morten Søndergaard, vi talte med. Både Moestrup og Fauth blev interviewet på Litteratursidens stand. Episoderne udkommer kronologisk i løbet af den første weekend i maj 2020.  God fornøjelse - og velkommen til et poetisk BogForum 2019. 

Den danske poeten og oversetteren Mette Moestrup forteller om Sylvia Plath og hennes roman, The Bell Jar (1963). Moestrup vil bl.a. diskutere forholdet mellom det private og politiske, overflate og dybde i Glassklokken, som hun i 2016 nyoversatte til dansk sammen med kollegaen Olga Ravn. Moestrup vil også fortelle om oversettelsessamarbeidet som metode.

Den danske poeten og oversetteren Mette Moestrup forteller om Sylvia Plath og hennes roman, The Bell Jar (1963). Moestrup vil bl.a. diskutere forholdet mellom det private og politiske, overflate og dybde i Glassklokken, som hun i 2016 nyoversatte til dansk sammen med kollegaen Olga Ravn. Moestrup vil også fortelle om oversettelsessamarbeidet som metode.

Gertrud Oelsner og Annette Rosenvold Hvidt var aldrig i tvivl om, at de skulle skrive deres store Hammershøi-biografi sammen, men »Frit flet« af Knutzon, Aidt og Moestrup inspirerede dem til, hvordan man kunne skabe en fælles skrift. See omnystudio.com/listener for privacy information. See omnystudio.com/listener for privacy information.

I denne episoden kan du høre de danske forfatterne Naja Marie Aidt, Line Knutzon og Mette Moestrup snakke om og lese fra felleboka Frit flæt. Samtalen ble ledet av feminist og journalist Helle Vaagland, og fant sted 30. januar 2015.   Litteraturhusets podkast presenterer bearbeidede versjoner av samtaler og foredrag i regi av Stiftelsen Litteraturhuset. Musikk av Apothek. See acast.com/privacy for privacy and opt-out information.

Host: Jeff Fox with special guests, Øjvind Moestrup, Peter Ulvskov, and Jesper Harholt. Øjvind Moestrup and Peter Ulvskov, both at the University of Copenhagen and Jesper Harholt at Carlsberg Laboratory, also in Copenhagen, Denmark, talk with Jeff Fox about their hypothesis about terrestrial plants, based on analyses of the cell walls of charophycean green algae. Moestrup, Peter Ulvskov, and Jesper Harholt thought that something was amiss with our current understanding of the evolutionary development of terrestrial plants after they carefully examined features of the cell walls of charophycean green algae. “Our hypothesis is simple,” they note. “Charophycean green algae ancestors were already living on land and had been doing so for some time before the emergence of land plants.” This new hypothesis takes issue with the widely accepted view that land plants originated from a charophycean green alga. "You have to be patient and sometimes pursue your crazy ideas, even when they differ from the dogmatic thinking in the field," Harholt says. "If you pile up enough evidence, at some point you may realize that you might be correct." This story was featured in the March 2016 issue of Microbe Magazine. Subscribe to MMP (free) on iTunes, Stitcher, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Send your microbiology questions and comments (email or audio file) to jfox@asmusa.org

Danish writer Mette Moestrup praises the way artist Pia Arke explored the difficult relationship between Denmark and Greenland, its former colony. Arke was the child of a Danish father and a Greenlandic mother. "My pictoral work deals almost exclusively with the silence that surrounds the bonds between Greenland and Denmark," she wrote. "I was myself born into that silence."One of Arke's projects involved the construction of a giant Camera Obscura on the site of her long demolished childhood home at Cape Nuugaarsuk in Greenland. The camera looked like "a big ice-cube among the barren mountains", says Moestrup. The artist was able to sit inside the camera as she took landscape and portrait shots. "Here," says Moestrup, "she created beautiful, haunting, hazy photographs of the bare rocky formations, the water and the ice. A lost home, and a lost view recreated via the nomadic camera house."This edition of The Essay is one of a series in which five writers each consider the significance of a work of art to their nation, as part of Radio 3's Northern Lights season.Producer: Andy Denwood.