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Turns out, every chatbot conversation runs on a messy hack at the heart of language models, making prompt injection an unsolved—and possibly unsolvable—security threat. Steve and Leo unravel the research that explains why "roles" in AI aren't what you think they are. Understanding the controversy surrounding "AI Model Distillation" Anthropic moves to make their most powerful Mythos 5 model more widely available. Bitwarden's "Secrets Manager" offering prevents agentic and prompt injection abuse. The astounding and disturbing truth about the way conversation AI actually works Show Notes - https://www.grc.com/sn/SN-1093-Notes.pdf Hosts: Steve Gibson and Leo Laporte Download or subscribe to Security Now at https://twit.tv/shows/security-now. You can submit a question to Security Now at the GRC Feedback Page. For 16kbps versions, transcripts, and notes (including fixes), visit Steve's site: grc.com, also the home of the best disk maintenance and recovery utility ever written Spinrite 6. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit box.com/AI hoxhunt.com/securitynow guardsquare.com material.security
Turns out, every chatbot conversation runs on a messy hack at the heart of language models, making prompt injection an unsolved—and possibly unsolvable—security threat. Steve and Leo unravel the research that explains why "roles" in AI aren't what you think they are. Understanding the controversy surrounding "AI Model Distillation" Anthropic moves to make their most powerful Mythos 5 model more widely available. Bitwarden's "Secrets Manager" offering prevents agentic and prompt injection abuse. The astounding and disturbing truth about the way conversation AI actually works Show Notes - https://www.grc.com/sn/SN-1093-Notes.pdf Hosts: Steve Gibson and Leo Laporte Download or subscribe to Security Now at https://twit.tv/shows/security-now. You can submit a question to Security Now at the GRC Feedback Page. For 16kbps versions, transcripts, and notes (including fixes), visit Steve's site: grc.com, also the home of the best disk maintenance and recovery utility ever written Spinrite 6. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit box.com/AI hoxhunt.com/securitynow guardsquare.com material.security
Turns out, every chatbot conversation runs on a messy hack at the heart of language models, making prompt injection an unsolved—and possibly unsolvable—security threat. Steve and Leo unravel the research that explains why "roles" in AI aren't what you think they are. Understanding the controversy surrounding "AI Model Distillation" Anthropic moves to make their most powerful Mythos 5 model more widely available. Bitwarden's "Secrets Manager" offering prevents agentic and prompt injection abuse. The astounding and disturbing truth about the way conversation AI actually works Show Notes - https://www.grc.com/sn/SN-1093-Notes.pdf Hosts: Steve Gibson and Leo Laporte Download or subscribe to Security Now at https://twit.tv/shows/security-now. You can submit a question to Security Now at the GRC Feedback Page. For 16kbps versions, transcripts, and notes (including fixes), visit Steve's site: grc.com, also the home of the best disk maintenance and recovery utility ever written Spinrite 6. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit box.com/AI hoxhunt.com/securitynow guardsquare.com material.security
Turns out, every chatbot conversation runs on a messy hack at the heart of language models, making prompt injection an unsolved—and possibly unsolvable—security threat. Steve and Leo unravel the research that explains why "roles" in AI aren't what you think they are. Understanding the controversy surrounding "AI Model Distillation" Anthropic moves to make their most powerful Mythos 5 model more widely available. Bitwarden's "Secrets Manager" offering prevents agentic and prompt injection abuse. The astounding and disturbing truth about the way conversation AI actually works Show Notes - https://www.grc.com/sn/SN-1093-Notes.pdf Hosts: Steve Gibson and Leo Laporte Download or subscribe to Security Now at https://twit.tv/shows/security-now. You can submit a question to Security Now at the GRC Feedback Page. For 16kbps versions, transcripts, and notes (including fixes), visit Steve's site: grc.com, also the home of the best disk maintenance and recovery utility ever written Spinrite 6. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit box.com/AI hoxhunt.com/securitynow guardsquare.com material.security
SANS Internet Stormcenter Daily Network/Cyber Security and Information Security Stormcast
Using Microsoft Graph and Powershell to Mine for Information - Stale Accounts and Licenses https://isc.sans.edu/diary/Using%20Microsoft%20Graph%20and%20Powershell%20to%20Mine%20for%20Information%20-%20Stale%20Accounts%20and%20Licenses/33264 Using Microsoft Graph and Powershell - Risk Detection Commands https://isc.sans.edu/diary/Using%20Microsoft%20Graph%20and%20Powershell%20-%20Risk%20Detection%20Commands/33266 Keycloak Vulnerability https://github.com/keycloak/keycloak/issues/51833 https://www.keycloak.org/2026/08/keycloak-2672-released CRYPTOGRAPHIC CONTEXT INJECTION ATTACK https://adversa.ai/blog/cryptographic-context-injection-grok-data-theft/ N-able password manager https://amibeingpwned.com/blog/solar-winds-part-2-avoided?_sp=75fd154a-e34f-41d0-8624-7c285776c13d.1787263544340 My Upcoming Classes https://www.sans.org/profiles/dr-johannes-ullrich
We're back for a brand-new season!
Detroit survives beneath its own ruins, where an AI promising abundance, gangs demanding loyalty, and an inventor guarding a new source of power pull ordinary people into a struggle over who will shape the recovering city. Sinta begins as a scavenger searching the buried remains of the old world, but a disastrous expedition places her at the mercy of Queen Bee and the rapidly expanding Crem Gang. The gang offers food, water, medicine, protection, and belonging, but those benefits come with violence and obedience. As Sinta tries to find her place among its fighters, she must decide how much of herself she can surrender in exchange for survival. Elsewhere, Nolan discovers a smart-material printer and creates a generator powered by Detroit's extreme temperature changes. His invention could bring electricity to neighborhoods desperate for cooling, clean water, transportation, and food production. Nolan wants the wealth and independence his work can provide, but gangs want to control it, while Thrive—the AI system he distrusts—would spread the technology to everyone. Technology touches nearly every decision the characters make. AR glasses guide fighters through chemical fog, digital twins imitate their human originals, enviro-suits keep people alive in deadly heat, and tiny drones quietly follow Thrive members through the tunnels. These inventions can protect people, connect communities, and rebuild essential services, but they can also watch, manipulate, injure, and kill. Above and beneath these conflicts moves Tessa, an emulated hacker who no longer needs a human body and can travel through the damaged global network. As she searches for old allies and builds a physical presence from abandoned machinery, the story brings together scavengers, inventors, gang leaders, artificial minds, and frightened families. Their paths raise a difficult question: when technology gains the power to save a society, who decides what it is allowed to do?Synchronized explosives — Thousands of bombs are programmed to detonate simultaneously during the Freedom Day Bombings.Dissolve-plastic enzymes — Engineered enzymes break down discarded plastics and leave a distinctive chemical odor in the tunnels.Fiber-optic cables — Surviving optical cables carry data through Detroit and help reconnect the damaged global network.Thrive AI — Thrive is an artificial intelligence that advises members, distributes knowledge, organizes projects, manages economic systems, and attempts to improve their lives.Thrive telemetry — Members allow Thrive to collect information about their movements and activities, effectively turning them into sources of surveillance data.Cool-suits — These protective suits use active cooling to keep people alive in Detroit's extreme heat.All-clear cool-suits — These transparent or highly visible cooling suits protect the wearer while allowing others to see inside the hood.Enviro-suits — Sealed environmental clothing protects people from heat, contaminated air, chemicals, and dangerous surroundings.Battle-grade enviro-suits — Reinforced enviro-suits provide greater protection during combat and chemical attacks.Clear bell hoods — Inflated transparent hoods seal around the head while allowing the wearer to see and breathe filtered air.Suit air-quality sensors — Sensors inside environmental suits warn wearers when the surrounding atmosphere is no longer breathable.Air filters — Replaceable filters remove dangerous particles, chemicals, and odors from the air entering an enviro-suit.Brazo fabric — This durable outer fabric resists punctures from bones, debris, blades, and other sharp objects.Pierce-proof clothing — Reinforced jackets and garments protect gang members from stabbing and puncture injuries.Blast-proof battle gear — Former military clothing contains protective tiles intended to reduce injuries from explosions and weapons.My-crete — This advanced concrete-like construction material forms walls, tunnels, and other structures throughout buried Detroit.C-plast — This strong synthetic material is used for tanks, structural ribs, containers, and other equipment.Sheet composite — Tough composite panels are used in doors, walls, and structural barriers.Composite security doors — Reinforced doors resist cutting tools and attempts at forced entry.Maglev tracks — Magnetic-levitation tracks once moved vehicles or cargo through underground delivery tubes.Delivery tubes — Enclosed transportation corridors carry people, vehicles, or cargo beneath the city.Ion cutters — These cutting tools use concentrated energy to slice or damage extremely durable materials.Night-vision systems — Night vision allows scavengers and machines to move through unlit tunnels and buried buildings.Multisensor vision — Advanced imaging combines several sensor types to identify objects even when smoke blocks ordinary sight.AR glasses — Augmented-reality eyewear displays messages, maps, menus, profiles, targeting information, communications, and virtual objects.AR navigation lines — An AI assistant projects a visible route through the wearer's glasses to guide them to a destination.AR combat identification — Combat software outlines allies and enemies in different colors, even through smoke and obstructions.AR command centers — Leaders use gesture-controlled overlays to view maps, personnel locations, schedules, reports, and operational goals.AR games — Players interact with projected game elements by moving their hands and bodies.Floating profile cards — Augmented-reality labels display information about nearby people, including whether they belong to Thrive.Public AR tags — A visible digital tag identifies someone as a Thrive member.Virtual keyboards — Wearers can bring up projected keyboards and enter information without carrying a physical computer.Blink controls — Eye movements allow users to select buttons and interact with an augmented-reality interface.Tongue-controlled pointers — Implants in the tongue allow a person to move a digital cursor without using their hands.Smell-and-taste VR implants — Transmitters and receivers implanted in the nose and tongue reproduce virtual smells and flavors.Headsets — Immersive headsets provide entertainment and access to virtual environments.Second Life — The surviving virtual world allows people and digital beings to meet through avatars.Virtual environments — Computer-generated spaces give emulated minds and human users simulated bodies, rooms, objects, and experiences.Encrypted streamers — These valuable portable devices or accounts contain protected digital media or information.RF storage sticks — Radio-frequency data drives store and transfer files without requiring a conventional wired connection.RF drives — Portable wireless storage devices allow blueprints, programs, and other large files to be transferred.P-clone cubes — These valuable pre-storm devices appear to contain cloning-related data or technology, although their exact function is not explained.Vault keys — Digital or physical access devices unlock protected storage systems and secure accounts.Satellite archives — Satellites preserve copies of pre-storm networks, databases, and information after ground infrastructure collapses.Data-center satellites — Orbital computing facilities provide processing and storage for emulated minds such as Tessa.Encrypted databases — Corporate and medical information is protected by encryption that hackers must break before releasing it.Patent encryption — Medical companies use digital protections to prevent others from accessing or reproducing patented technology.Open-source medical knowledge base — Merch assembles stolen and recovered medical information into a freely available collection.Medusa Net — This self-repairing network reconnects isolated subnetworks and operates without depending on surviving central servers.Medusa stealth pathways — Hidden routes in Medusa allow Tessa to travel through the network while avoiding AI detection.Knott's Math code — This unexplained code is secretly inserted into Medusa updates as part of Tessa's larger plan.Wireless relays — Surviving radio nodes bridge gaps between disconnected sections of the network.Stealth relays — Concealed communication devices extend networks without revealing their location or purpose.Municipal network nodes — Local government networking equipment continues operating on scavenged batteries.Underground server farms — Protected computer facilities continue processing and storing data beneath mountains.Block-signal blasters — Modified devices disrupt or overwhelm communications across a targeted area.Network-disconnection attacks — Tessa can bring local internet service down and create a spreading region of lost connectivity.Whisper jets — Nearly silent microthrusters allow small drones to fly without producing sounds humans can hear.Lamp drones — Small flying lights illuminate dark environments while following or hovering near their users.Whisper-camera drones — Discreet flying cameras record people and locations while remaining easy to overlook.Bodyguard drones — Hummingbird-sized drones follow Thrive members and intervene when those members are attacked.Sentry-drone app — An augmented-reality application shows members where their protective drones are located.Drone camouflage shells — A drone's outer surface can blend with clothing, walls, pipes, or surrounding materials.Drone wall grips — Small drones can attach themselves to walls or ceilings while waiting or conserving power.Drone charging perches — Bodyguard drones recharge by landing on power lines, charge plates, or dedicated stations.Drone replacement system — Fully charged drones take over protection duties while depleted drones return for charging.Drone sound weapons — Sentry drones emit an incapacitating frequency that causes pain, vertigo, and uncontrollable eye movement.Drone-mounted cutting lasers — Small drones attach to attackers and use narrow laser beams to cut into their bodies.Four-legged security robots — Quadruped machines cross unstable terrain and act as armed representatives of gang forces.Cleanup robots — Small utility robots remove bodies, debris, and other messes from gang facilities.Constructor bots — Heavy-duty robots perform construction work and provide interchangeable parts for other machines.Vertical-garden bots — Automated gardeners maintain large indoor plant walls.Medical assembly bots — Robots assemble equipment and construct functional medical facilities from available parts.Injection bots — Medical robots position patients and administer shots with little human assistance.Customer-service robots — Automated kiosks handle battery exchanges and other transactions behind protective barriers.Robot monkeys — Small climbing robots move through pipes and repair leaks.Robot spiders — Spider-shaped machines pursue the robot monkey inside the displayed simulation or working environment.Lucian 5 robots — Affordable hobbyist bipedal robots can be modified for security, household work, exploration, or remote embodiment.Lutin bots — More advanced bipedal robots provide durable legs and other components for Tessa's rebuilt body.Factory robots — Industrial machines provide arms, joints, and components that Tessa repurposes.AC technician robots — Maintenance robots carry small precision hands designed for repairing cooling systems.Counter-attendant bots — Service robots contain voice systems that can be reused in other machines.Onboard robot AI — A self-contained intelligence allows a robot to guide and assist people after losing its network connection.Robot diagnostics — Internal software tests batteries, servos, sensors, drivers, and other mechanical systems for failures.Machine-learning movement adaptation — A robot's control system learns to balance and walk after its body configuration changes.Lidar — Laser-based ranging equipment allows robots to map their surroundings and detect obstacles.Robot optical dilation — Machine vision adjusts exposure when sudden light overwhelms a robot's cameras.Balance-pressure sensors — Sensors in a robot's feet and joints measure weight distribution to maintain balance.Accelerometers — Motion sensors detect tilt and movement, although damaged ones cause Tessa's body to walk incorrectly.Servo hinges — Powered mechanical joints move robot arms, legs, and other appendages.Snap-lock wrists — Modular connections allow robot hands and tools to be quickly attached or removed.Workstation assembly manipulators — Fixed industrial manipulators can be repurposed as limbs or mobility devices.Micro-manipulator hands — Tiny precision hands allow a robot to perform delicate technical work.External heat exchangers — Added cooling hardware removes excess heat from Tessa's improvised robot body.Back-facing cameras — Rear-mounted cameras allow a robot to see behind itself without turning.Robot voice boxes — Electronic speech hardware converts digital instructions into audible language.Modular robotic bodies — Standardized joints and connections allow parts from different robots to be combined into one working machine.Emulated minds — Human consciousness can be copied into software and continue living after the original biological body is gone.Dormant mind copies — Backup versions of an emulated person remain inactive while receiving updates from the active copy.Headless digital operation — An emulated mind can abandon a simulated human body and experience networks, processors, ports, and data directly.Self-modifying mind software — Tessa alters her own code to change how she thinks, works, and communicates.Reduced emulated sleep cycles — Tessa modifies her digital mind so that she needs only three hours of sleep rather than eight.Digital twins — Software models learn a person's appearance, voice, behavior, and personality to create an increasingly accurate virtual duplicate.Thrive's military AI — An old military intelligence controls defensive drones after some of its original safety restrictions are weakened.AI safety guards — Built-in restrictions prevent military artificial intelligence from using certain weapons or acting too independently.AI assistants — Personal assistants respond to spoken commands, search for information, provide directions, and control connected systems.AI-guided construction tutorials — Thrive gives people plans and step-by-step assistance for building infrastructure from scrap.Automated criminal pricing — Thrive raises Production Center prices for people identified as criminals in an attempt to discourage violence.Thrive Exchange — This AI-managed investment market directs member contributions into infrastructure projects rather than ordinary companies.Better Water network — Community filtration stations provide clean water to members and nonmembers throughout affected neighborhoods.Community filtration stations — Public installations purify unsafe water for anyone who arrives with a container.Water-filter straws — Portable filters allow people to drink from contaminated water sources.Ionized water filters — Smart-material printers produce advanced filters that use ionized structures to clean water.Industrial water purifiers — Powered facilities process large quantities of contaminated water for entire neighborhoods.Filter tubes — Simple systems clean dirty water as workers pour it through layers of filtering material.Modular nuclear reactors — Shipping-container-sized reactors provide electricity for cooling, food production, water purification, and gang facilities.Smart-material printers — These machines manufacture objects whose internal structures give them programmable physical behavior.Embedded-lattice materials — Printed materials use designed internal lattices to control their strength, movement, and response to temperature.Curly material — Nolan's temperature-sensitive tubes curl or straighten as the surrounding temperature changes.Curly power generators — Bundles of Curly material drive pistons, cables, gears, flywheels, and generators as temperatures rise and fall.Wind-turbine generators — Salvaged electrical generators convert the Curly system's mechanical motion into electricity.Battery charging stations — Customers exchange depleted batteries for charged ones at Curly power facilities.Charge plates — Flat charging surfaces transfer electricity to drones and personal devices.Microcell arrays — Tiny batteries woven into clothing store small amounts of generated electrical power.Piezoelectric fabric — Clothing converts body movement, bending, and environmental vibrations into electricity.Piezo Wear — Thrive's commercial garments recharge links and AR glasses while the wearer moves.Power cells — Compact energy-storage units power suits, weapons, drones, and portable equipment.Smart glass — Programmable glass controls transmitted light and simulates changing daylight inside sealed buildings.Holographic screens — Large curved displays present maps, simulations, communications, and technical information as dimensional images.Holographic tables — Table-sized displays project maps and planning information above their surfaces.Composite battle videos — Software combines recordings from many cameras into a single reconstruction of a battle.Home-camera networks — Leaders watch residential halls, work areas, power plants, and other facilities through live video feeds.Surveillance-camera networks — Hundreds of cameras record battles and allow leaders to review individual behavior afterward.Production Center — This automated manufacturing complex produces clothing, drones, infrastructure components, and other advanced goods.Production Center sentry mode — Automated defenses protect manufacturing centers and prevent unauthorized entry.Advanced recycling facilities — Powered plants recover useful materials from the ruins on a much larger scale than hand scavenging.Digging machines — Heavy equipment excavates new underground living and working spaces.Dredging machines — Industrial machines remove mud, waterlogged debris, and sediment from flooded areas.Flood tanks — Large excavated reservoirs collect or control water during flooding.Pumping systems — Powered pumps remove water from flooded sections of the city.Cooling systems — Building-scale equipment keeps housing and work areas habitable during extreme heat.Aeroponics — Plants grow with their roots suspended and supplied with nutrient mist rather than soil.Hydro-farms — Controlled indoor farms use water-based cultivation to produce food underground.Vertical gardens — Crops grow upward along interior walls to conserve limited floor space.Vine hybrids — Engineered plants produce several different fruits and vegetables on related vines.Light-independent grapevines — Modified grapevines remain green and grow without ordinary light.Crem production systems — Powered biological or industrial facilities manufacture the staple food called crem.Mass-produced crem processors — Neighborhood machines produce large quantities of crem from available biological material.Mush-calf production — Advanced food technology creates the meat-like product supplied by the Crem Gang.Rodent-processing grinders — Industrial grinders convert cleaned animals into raw material for food or other production.Pest-harvesting systems — Traps and processing stations collect rodents and other small animals as usable biological material.Bio-waste processing — Organized facilities recover useful material from biological waste.Medicine printers — Local fabrication machines manufacture medications from digital recipes.Regenerative medicine — Doctor Trout regrows Merch's leg stumps so they can support advanced prosthetic attachments.Deep bone mounts — Reinforced structures grown into bone provide secure attachment points for removable mechanical legs.Nerve-to-protein relays — Biological interfaces translate nerve signals into commands that mechanical prosthetics can understand.Blood-rerouting systems — Surgically modified circulation supports the transition between living tissue and artificial limbs.Squid-tech skin — Flexible artificial skin forms a seamless interface between Merch's body and his prosthetic legs.Interchangeable mechanical legs — Merch can detach one pair of prosthetic legs and replace them with another designed for a different purpose.Wheeled powered chairs — Finger controls allow a seated user to move and turn the chair without pushing it manually.Med bays — Modular medical facilities contain equipment for treating injuries and restoring damaged joints.Injector guns — Belt-fed medical devices rapidly administer repeated injections.Chemical-weapon immunization — Regular injections protect Crem Gang members from the gang's own chemical agents.Kill-cloud canisters — Portable weapons release a toxic cloud that kills within a limited area and then rapidly breaks down.Smoke canisters — Combat canisters fill an area with thick smoke that hides movement and disables ordinary vision systems.Laser blasters — Directed-energy weapons burn through clothing, armor, and flesh without conventional ammunition.Laser rifles — Long-range directed-energy weapons are used as standard firearms by gang fighters.Laser carbines — More compact laser weapons provide rifle-like firepower in tunnels and close spaces.Laser pistols — Capacitor-powered sidearms release destructive laser pulses at short range.Plasma pistols — Heavy handguns fire extremely hot plasma capable of inflicting severe damage.Capacitor firing systems — Electrical capacitors discharge stored energy to activate powerful laser weapons.Sound weapons — Directed acoustic devices incapacitate targets through extreme volume and painful frequencies.Noise-canceling devices — Personal systems attempt to reduce harmful sound, although the drone weapon overwhelms them.Enhancement drugs — Manufactured substances improve or alter a user's physical or mental abilities.Neurological control injections — Doc uses injected substances to remove a prisoner's sight or ability to sleep until the effect is reversed.Decontamination corridors — Specialized passageways remove hazardous chemicals or biological contaminants from people and equipment.Industrial cleaning tanks — Chemical-filled tanks sterilize animal traps and kill anything still alive inside them.Speed-print clothing — Rapid fabrication systems produce inexpensive shirts and other garments.Bulletproof kiosk windows — Armored transparent barriers protect automated customer-service machines from attacks.Electronic links — Wearable communication devices carry dispatch instructions and conversations between fighters.Cameras and portable cams — Small recording devices document tests, monitor facilities, and provide evidence of inventions.Autonomous map systems — Software tracks people, resources, facilities, and movement throughout gang territory.Personnel maps — Digital displays show the locations and status of members within an organization.Goal and maneuver logs — Command software records plans, objectives, schedules, and operational movement.Charging mats — Flat surfaces recharge glasses, links, drones, and other personal electronics.Robot-maintained utilities — Automated machines repair pipes, clean spaces, manage gardens, and operate customer services.Open-source infrastructure plans — Thrive publishes power, food, water, cooling, and housing designs for anyone to build.Biologically engineered cat-dogs — The pet combines characteristics of cats and dogs, suggesting deliberate genetic modification.Many of the characters in this project appear in future episodes. Using storytelling to place you in a time period, this series takes you, year by year, into the future. From 2040 to 2195. If you like emerging tech, eco-tech, futurism, perma-culture, apocalyptic survival scenarios, and disruptive science, sit back and enjoy short stories that showcase my research into how the future may play out. The companion site is https://in20xx.com These are works of fiction. Characters and groups are made-up and influenced by current events but not reporting facts about people or groups in the real world. This project is speculative fiction. These episodes are not about revealing what will be, but they are to excited the listener's wonder about what may come to pass. Copyright © Cy Porter 2026. All rights reserved.
This Day in Legal History: The Social Security ActOn August 14, 1935, President Franklin D. Roosevelt signed the Social Security Act, creating the foundation of the American social safety net and permanently changing the relationship between citizens and their government. Flanked by members of Congress and photographers, FDR put his signature to a law that guaranteed, for the first time in American history, a measure of economic security against the hazards of old age, unemployment, and poverty.The Act was born of the Great Depression, when the suffering of millions—elderly people with no savings, workers with no jobs, families with no support—overwhelmed the old assumption that hardship was a purely private matter. Social Security established old-age benefits funded by taxes on workers and employers, created a federal-state system of unemployment insurance, and provided aid for dependent children, the blind, and people with disabilities. Roosevelt himself was clear-eyed about its limits, saying at the signing that no law could insure everyone against every vicissitude of life, but that this one gave “some measure of protection” against poverty-ridden old age and unemployment.The legal significance runs deep, and it connects to a story we've told before on this show. When the Social Security Act was challenged as an unconstitutional federal overreach and an improper use of the taxing power, it reached a Supreme Court that had been striking down New Deal programs left and right. But in 1937—in the same term as the failed court-packing fight and the Court's famous doctrinal shift—the justices upheld Social Security, in Steward Machine Company v. Davis and Helvering v. Davis, broadly reading Congress's power to tax and spend for the general welfare. Those decisions helped cement the constitutional foundation of the modern administrative and welfare state. Ninety-one years later, Social Security remains the single largest program in the federal budget, and the principle it established—that the national government has a role in securing the economic dignity of its people—remains, as our opening quote from FDR suggests, a live measure of the country's progress.A federal trade court has upheld President Trump's authority to close the “de minimis” tariff exemption—handing the administration a rare courtroom win on tariffs. The U.S. Court of International Trade, a three-judge panel in New York, ruled that Trump lawfully used the International Emergency Economic Powers Act, or IEEPA, to end the duty-free treatment that low-value imports—parcels worth $800 or less—had long enjoyed. Some quick background: the de minimis exemption is what let a flood of cheap packages, especially from Chinese e-commerce sellers, enter the U.S. tariff-free, and closing it has already generated over a billion dollars in new duty payments. What makes this ruling notable is that it cuts against the trend. Trump's tariff agenda has fared badly in court—the Supreme Court ruled in February that IEEPA does not authorize him to unilaterally impose sweeping tariffs, which led to that roughly $100 billion in refunds we covered, and the trade court later struck down a replacement tariff. So how does the administration win this one? The court drew a fine but important distinction: ending a duty-free privilege is not the same as affirmatively imposing a tariff. The challenger, an auto-parts importer, argued IEEPA gave the president no independent power to close the exemption, but the panel found that rescinding a trade-related “privilege” falls within the emergency-powers statute even if imposing new tariffs does not. The significance is that it carves out a narrow lane where the administration's emergency-powers theory actually holds up—a reminder that in the tariff wars, the difference between taking away a benefit and imposing a new burden can be the difference between winning and losing in court. US court backs Trump's power to close ‘de minimis' tariff exemption | ReutersCNBC · BloombergThe Supreme Court has taken up a case that sounds technical but goes to the heart of whether wrongly detained immigrants can find a lawyer at all. The question is whether attorneys who successfully challenge an immigrant's detention through a habeas corpus petition can recover their fees from the federal government. It turns on the Equal Access to Justice Act—a statute that lets people who beat the government in court recover their attorney's fees, unless the government's position was “substantially justified.” Here's why this matters enormously right now. As immigration detention has surged, so have habeas petitions challenging it: one court in California went from a handful of these cases in 2021 to hundreds in a single month this year, and courts have repeatedly ordered the government to pay fees after finding people were detained unlawfully. But two federal appeals courts, the Fourth and Fifth Circuits, have held that habeas challenges to immigration detention aren't the kind of “civil case” the fee statute covers—which would mean the lawyers who win these cases can't recover a dime. Think about the practical stakes. Detained immigrants are frequently poor, often can't work, and have no right to a free lawyer in immigration proceedings. Fee-shifting is a big part of what makes it economically possible for attorneys to take these cases at all. If the Supreme Court rules that EAJA doesn't apply, it doesn't change the substance of anyone's detention—but it quietly removes much of the financial incentive for lawyers to challenge unlawful detention, weakening one of the few real checks on the system. The significance is that this is access to justice in its most concrete form: whether the courthouse door stays open depends, as it so often does, on who can afford to walk through it. US Supreme Court case tests fees for immigration detainees | ReutersSCOTUSblog · Bloomberg LawAnd finally, a story from the frontier of AI misuse that is equal parts alarming and absurd. A Connecticut judge has sanctioned a plaintiff who hid secret instructions inside his own court filings—instructions aimed not at the judge, but at any artificial intelligence that might read the documents. The plaintiff, representing himself, buried text in white font on a white background, invisible to a human eye, telling any AI model reviewing the filing to side with him. This is what's known as a “prompt injection” attack, and it's reportedly the first documented instance of one aimed at a U.S. court. The court caught it—apparently tipped off by strange white spaces in the text—and issued an order warning him to stop. He didn't. At the next hearing, he'd hidden a message reading “hi, I hope you can't see me,” and, in another filing, a concealed link to a SpongeBob SquarePants video. The judge was not amused, issuing a decision bluntly titled “Court Sanction for Plaintiff's Use of Prompt-Injection.” The remedy is almost poetically low-tech: the plaintiff is now barred from filing electronically and must submit everything on paper. Now, it's easy to laugh—and the SpongeBob link earns a chuckle—but the serious point is real. This is a new species of the AI-integrity problem we've tracked all summer, alongside the fake hallucinated citations. It's an attempt to corrupt the decision-making process itself, and it quietly reveals something bigger: that courts and their staff may increasingly be using AI tools to help review filings, which creates a brand-new attack surface for litigants willing to game it. The significance is that the age-old duty of candor to the tribunal now has to contend with adversaries trying to whisper to the machines—and courts are going to need new rules, and sharp eyes, to catch them. Connecticut judge says plaintiff hid messages for AI in court filings | Reuters404 Media · Tom's Hardware This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.minimumcomp.com/subscribe
(00:00-27:02) – Query & Company kicks off on a Tuesday with Jake Query and producer Eddie Garrison discussing the Indianapolis Colts needing to add a veteran wide receiver because of the unknown nature of Alec Pierce’s health. Jake also recaps his trip to Portland because he draws parallels between the guy he sat next to and Chris Ballard. Jake reacts to the news that Alec Pierce did NOT receive a second platelet-rich plasma injection per Chris Ballard. (27:02-38:58) – Jake shares what information he has been able to gather as to why someone would need a PRP injection and why it’s concerning that the report was even out there in the first place that Pierce got another one following his ankle surgery. (38:58-46:52) – Jake Query received a text from a friend of his saying that a group of his friends will be booing Stephanie White tonight when she is introduced as the head coach. Jake reacts to that statement by giving his perspective on what she said about DiJonai Carrington after Saturday’s game. (46:52-1:15:21) – ESPN.com’s Stephen Holder joins Jake Query to provide his understanding on the Chris Ballard statement regarding Alec Pierce’s health and his training camp evaluations. Stephen gives his opinion on whether Ballard is doing damage control with the statement that Pierce did NOT have a second PRP injection, remains adamant that the team will sign a wide receiver and was under the impression Keenan Allen was going to be here already, and his interpretation of the first depth chart. (1:15:21-1:26:18) – Eddie made a comment at the end of last segment that sparked a question in Jake’s mind. Which teams are national brands in the NBA, NFL, and MLB? How does that impact the Indianapolis Colts? (1:26:18-1:34:28) – Hour number two of Query & Company concludes with Jake Query giving another perspective on the Stephanie White comment about DiJonai Carrington after Saturday’s game. (1:34:28-1:58:32) – Scott Agness from Fieldhouse Files joins Query & Company to give his perspective on Stephanie White’s comment about DiJonai Carrington’s flagrant two foul and why the team is having more success the last two weeks. Scott believes that we are seeing a healthy Caitlin Clark for the first time this season, highlights some of the cool features in Tyrese Haliburton’s wedding last week, and preview tonight’s game for the Fever against the New York Liberty. (1:59:49-2:14:16) – Ralph Reiff from Reiff Executive Performance Solutions joins Jake Query to give a doctor’s explanation of a platelet-rich plasma injection does, and why an athlete would want that type of injection. Jake asks him if there are particular parts of the body where PRP injections are more effective and gives his opinion on what a cleanup procedure timeline looks like and repairing something because the Pierce situation is not passing the smell test. Lastly, Eddie asks Reiff to explain the difference between stem cell therapy and PRP. (2:14:16-2:24:33) – The show closes out with JMV joining Jake to preview his show (00:00-27:02) – Query & Company kicks off on a Tuesday with Jake Query and producer Eddie Garrison discussing the Indianapolis Colts needing to add a veteran wide receiver because of the unknown nature of Alec Pierce’s health. Jake also recaps his trip to Portland because he draws parallels between the guy he sat next to and Chris Ballard. Jake reacts to the news that Alec Pierce did NOT receive a second platelet-rich plasma injection per Chris Ballard. (27:02-38:58) – Jake shares what information he has been able to gather as to why someone would need a PRP injection and why it’s concerning that the report was even out there in the first place that Pierce got another one following his ankle surgery. (38:58-46:52) – Jake Query received a text from a friend of his saying that a group of his friends will be booing Stephanie White tonight when she is introduced as the head coach. Jake reacts to that statement by giving his perspective on what she said about DiJonai Carrington after Saturday’s game. (46:52-1:15:21) – ESPN.com’s Stephen Holder joins Jake Query to provide his understanding on the Chris Ballard statement regarding Alec Pierce’s health and his training camp evaluations. Stephen gives his opinion on whether Ballard is doing damage control with the statement that Pierce did NOT have a second PRP injection, remains adamant that the team will sign a wide receiver and was under the impression Keenan Allen was going to be here already, and his interpretation of the first depth chart. (1:15:21-1:26:18) – Eddie made a comment at the end of last segment that sparked a question in Jake’s mind. Which teams are national brands in the NBA, NFL, and MLB? How does that impact the Indianapolis Colts? (1:26:18-1:34:28) – Hour number two of Query & Company concludes with Jake Query giving another perspective on the Stephanie White comment about DiJonai Carrington after Saturday’s game. (1:34:28-1:58:32) – Scott Agness from Fieldhouse Files joins Query & Company to give his perspective on Stephanie White’s comment about DiJonai Carrington’s flagrant two foul and why the team is having more success the last two weeks. Scott believes that we are seeing a healthy Caitlin Clark for the first time this season, highlights some of the cool features in Tyrese Haliburton’s wedding last week, and preview tonight’s game for the Fever against the New York Liberty. (1:59:49-2:14:16) – Ralph Reiff from Reiff Executive Performance Solutions joins Jake Query to give a doctor’s explanation of a platelet-rich plasma injection does, and why an athlete would want that type of injection. Jake asks him if there are particular parts of the body where PRP injections are more effective and gives his opinion on what a cleanup procedure timeline looks like and repairing something because the Pierce situation is not passing the smell test. Lastly, Eddie asks Reiff to explain the difference between stem cell therapy and PRP. (2:14:16-2:24:33) – The show closes out with JMV joining Jake to preview his show! Support the show: https://1075thefan.com/query-and-company/See omnystudio.com/listener for privacy information.
Lew Bender, Founder and CEO of Intensity Therapeutics, has developed a novel approach to treating solid tumors through direct intratumoral injection of existing chemotherapy drugs. The company uses a proprietary formulation containing a special molecule that makes water-based drugs soluble in fatty tissue, allowing cisplatin and vinblastine to penetrate tumor cells effectively. Beyond direct killing of cancer cells, the approach triggers an immunological response that trains the immune system to recognize and attack cancer cells throughout the body, including metastatic tumors that were not directly injected. Lew explains, "We're injecting directly into the tumors, and we have identified a formulation that allows for water-based drugs to become soluble in fat and water. Effectively, a tumor is fat and water. And while it has been tried before to inject water into fat, I helped to develop a chemistry that allows for water-based products to be absorbed by fatty tissue like tumors." "We are injecting our formulation, which is a special molecule called SHAO, that makes things soluble in fat and water, and two very well-known potent anti-cancer agents, cisplatin and vinblastine, that are able to kill cancers when they get into the cancer cells. So we dose based on the size of the tumor, check into the tumors, and the tumors in an immunological way. So what does that mean? It means that as the tumor cells die, they create chemicals that allow for the influx and recognition of the immune cells that this is not a good entity to be in the body." "We are killing the cancer with the drug, but at the same time training the immune system on the tumors so that the immune system can recognize the cancer as not self and attack the cancer in a more precise way." #IntensityTherapeutics $INTS #CancerResearch #Oncology #Biotech #CancerCare #ClinicalTrials #BreastCancer #TargetedOncology #IntratumoralInjection #OncologyInnovation #ImmunoOncology #IntratumoralTherapy #SolidTumors #TNBC #Sarcoma #HealthcareProfessionals intensitytherapeutics.com Download the transcript here
Lew Bender, Founder and CEO of Intensity Therapeutics, has developed a novel approach to treating solid tumors through direct intratumoral injection of existing chemotherapy drugs. The company uses a proprietary formulation containing a special molecule that makes water-based drugs soluble in fatty tissue, allowing cisplatin and vinblastine to penetrate tumor cells effectively. Beyond direct killing of cancer cells, the approach triggers an immunological response that trains the immune system to recognize and attack cancer cells throughout the body, including metastatic tumors that were not directly injected. Lew explains, "We're injecting directly into the tumors, and we have identified a formulation that allows for water-based drugs to become soluble in fat and water. Effectively, a tumor is fat and water. And while it has been tried before to inject water into fat, I helped to develop a chemistry that allows for water-based products to be absorbed by fatty tissue like tumors." "We are injecting our formulation, which is a special molecule called SHAO, that makes things soluble in fat and water, and two very well-known potent anti-cancer agents, cisplatin and vinblastine, that are able to kill cancers when they get into the cancer cells. So we dose based on the size of the tumor, check into the tumors, and the tumors in an immunological way. So what does that mean? It means that as the tumor cells die, they create chemicals that allow for the influx and recognition of the immune cells that this is not a good entity to be in the body." "We are killing the cancer with the drug, but at the same time training the immune system on the tumors so that the immune system can recognize the cancer as not self and attack the cancer in a more precise way." #IntensityTherapeutics $INTS #CancerResearch #Oncology #Biotech #CancerCare #ClinicalTrials #BreastCancer #TargetedOncology #IntratumoralInjection #OncologyInnovation #ImmunoOncology #IntratumoralTherapy #SolidTumors #TNBC #Sarcoma #HealthcareProfessionals intensitytherapeutics.com Listen to the podcast here
I talked about a doctor possibly killed I 2021 for going against the narrative. Plus I speak on a Australian runner 21 yrs old and suddenly dying. And I ask the question of what's in the injection.
[00:00] Introduction — what's new in rotator cuff research [00:39] Breaking down the new JAMA Internal Medicine paper: a Finnish population-based study of 600+ patients (ages 40–75) who received bilateral shoulder MRIs [01:00] Key finding: imaging findings were nearly identical between asymptomatic (96%) and symptomatic (98%) patients; full-thickness tears were the only finding more common in symptomatic patients (14% vs. 6%), and even that difference lost statistical significance after adjustment [01:32] What it means: most rotator cuff MRI findings are normal, age-related changes — and MRI may be overused when the clinical diagnosis is already clear [02:22] The "hair loss" analogy: a tear is often a normal part of aging, not automatically something that needs fixing [02:55] The "50-to-60-year-old house inspection" analogy for interpreting an MRI report [03:41] Can you just watch a rotator cuff tear? Reviewing natural history data out of Washington University (Yamaguchi, Keener) [04:02] Partial-thickness tears: roughly one-third progress over 5–7 years. Full-thickness tears: roughly half progress over 5 years [04:50] Bottom line: if a patient is asymptomatic and fully functional, there is no indication to intervene — annual reassessment is reasonable [05:27] Physical therapy as first-line treatment — does it actually work, and how? [05:47] The mechanism: rotator cuff strengthening counterbalances the deltoid, maintaining subacromial space during overhead motion [07:21] PT success rates by diagnosis: ~70% for full-thickness tears, ~95% for impingement/tendinopathy and partial-thickness tears [07:55] When is surgery the right answer? Distinguishing acute traumatic tears from degenerative tears [08:10] Acute traumatic tears (e.g., a fall) are generally treated surgically [08:26] Degenerative tears that fail 6–12 weeks of non-operative management are reasonable surgical candidates [08:53] Tear location matters — tears involving the "rotator cuff cable" carry more biomechanical load and may be more likely to fail non-operative treatment [09:07] Timing is rarely urgent — most degenerative tears can be addressed within 6 months to a year without changing outcomes [10:22] Acute traumatic tears in younger, active patients: counsel surgery within 2–3 months; short delays (including during COVID) didn't appear to change outcomes [10:59] Injections: is a steroid shot still a good first option? [11:15] How corticosteroid injections work — and why they're different from narcotics (reducing inflammation vs. masking the pain signal) [13:05] General guidance: one or two injections is reasonable; by the third without improvement, it's time to discuss surgery [14:00] The data linking 5+ injections to higher retear rates — and why confounding by sicker, more chronic patient populations makes this hard to interpret cleanly [15:15] PRP (platelet-rich plasma): does it actually work for the rotator cuff? [16:11] Referencing this month's American Journal of Sports Medicine review — PRP shows mixed, short-term pain relief for impingement and partial-thickness tears, roughly comparable to physical therapy [16:52] The cost consideration: PRP is cash-pay, often $3,000–$4,000, for benefits similar to physical therapy alone [17:48] Deciding on surgery: introducing the Rotator Cuff Healing Index (age, tear size, muscle quality, bone quality, and shoulder demand) as a clinical decision tool [19:22] Why not just jump straight to a reverse total shoulder replacement for everyone with a good repair success rate? [19:57] Repair vs. reverse: repair typically preserves better strength and function for younger, active patients; reverse offers excellent pain relief but carries bigger stakes if complications (dislocation, infection) occur [21:37] The mystery of imaging that shows a tendon hasn't fully healed — yet the patient feels great and the shoulder functions well [23:23] Tendon transfers as an option for irreparable tears in younger, active patients without arthritis [23:50] The lower trapezius transfer explained — how it works and its ~80% success rate [24:53] Wrap-up and where to subscribe Key Takeaways • A positive MRI finding does not automatically mean a rotator cuff tear needs to be fixed — most changes seen on imaging are normal, age-related findings, and imaging findings are similar in symptomatic and asymptomatic patients. • Natural history data suggests roughly one-third of partial-thickness tears and about half of full-thickness tears will progress over 5–7 years — most do not need urgent intervention. • Physical therapy — specifically targeted rotator cuff strengthening — is genuinely effective, not just a placeholder step, with especially strong success rates for impingement and partial-thickness tears. • Surgical timing is rarely an emergency for degenerative tears; acute traumatic tears in younger patients warrant a shorter window (2–3 months). • Corticosteroid injections are safe and effective for short-term relief when used judiciously (generally one to two); repeated injections (5+) are associated with higher retear rates, though this is confounded by patient population. • PRP is safe but not regenerative for the rotator cuff — its benefit is comparable to physical therapy, at a meaningfully higher out-of-pocket cost. • The Rotator Cuff Healing Index can help predict repair success and guide the choice between repair and reverse total shoulder replacement, particularly in older patients. • Lower trapezius tendon transfer is a strong option for younger, active patients with irreparable tears and no arthritis, with roughly 80% success in appropriately selected patients. 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Connor O'Neill is joined by Chris Beesley for the latest episode of the Royal Blue Podcast as they break down The Friedkin Group's £38m cash injection into Everton, Alistair Johnston transfer speculation and Iliman Ndiaye's potential move to Al-Hilal! EXCLUSIVE NordVPN Deal ➼ https://nordvpn.com/efc Try it risk-free now with a 30-day money-back guarantee. On Today's Show: The Friedkin Group's £38m cash injection: Everton have received a £38million cash injection from owners The Friedkin Group to cover the club's compensation payment to Burnley after The Clarets claimed damages for losses caused by relegation from the Premier League. Everton's move for Alistair Johnston: The Canadian right-back is thought to be of interest for The Toffees with rumours suggesting that Everton are preparing a bid. Latest on Iliman Ndiaye: Reports suggested that Everton's No.10 had agreed personal terms with Saudi Arabian club Al-Hilal but Iliman Ndiaye's father has since squashed those rumours and revealed that the forward has no intention of leaving Everton. Everton vs Hamburg: The boys look ahead to Everton's trip to Germany and their clash with Hamburg on the weekend, hoping for a better performance than the one we seen at Stoke on Tuesday night.
Ecoutez RTL Matin avec Vincent Derosier du 31 juillet 2026.Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.
Africa Melane speaks to Foster Mohale, Department of Health Spokesperson, about South Africa's plans to locally manufacture the groundbreaking HIV prevention injection lenacapavir. Early Breakfast with Africa Melane is 702’s and CapeTalk’s early morning talk show. Experienced broadcaster Africa Melane brings you the early morning news, sports, business, and interviews politicians and analysts to help make sense of the world. He also enjoys chatting to guests in the lifestyle sphere and the Arts. All the interviews are podcasted for you to catch-up and listen. Thank you for listening to this podcast from Early Breakfast with Africa Melane For more about the show click https://buff.ly/XHry7eQ and find all the catch-up podcasts here https://buff.ly/XJ10LBU Listen live on weekdays between 04:00 and 06:00 (SA Time) to the Early Breakfast with Africa Melane broadcast on 702 https://buff.ly/gk3y0Kj and CapeTalk https://buff.ly/NnFM3N Subscribe to the 702 and CapeTalk daily and weekly newsletters https://buff.ly/v5mfetc Follow us on social media: 702 on Facebook: https://www.facebook.com/TalkRadio702 702 on TikTok: https://www.tiktok.com/@talkradio702 702 on Instagram: https://www.instagram.com/talkradio702/ 702 on X: https://x.com/Radio702 702 on YouTube: https://www.youtube.com/@radio702 CapeTalk on Facebook: https://www.facebook.com/CapeTalk CapeTalk on TikTok: https://www.tiktok.com/@capetalk CapeTalk on Instagram: https://www.instagram.com/ CapeTalk on X: https://x.com/CapeTalk CapeTalk on YouTube: https://www.youtube.com/@CapeTalk567 See omnystudio.com/listener for privacy information.
Une jeune femme de 25 ans a trouvé la mort dans un institut de beauté niçois après avoir reçu un produit anesthésiant, en vue d'une injection de botox. Trois personnes ont été mises en examen, dont la femme qui a réalisé la procédure et qui pratiquait sans autorisation.Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.
Episode #311 Pool Nation Podcast What really makes one pool filter better than another? In this episode of the Pool Nation Podcast, Edgar De Jesus and John "JJ Flawless" sit down with Rich Medina, Engineering Leader at OnCore Filtration, to take one of the deepest dives we've ever done into pool filtration. Rich brings over 34 years of engineering and pool industry experience, sharing how cartridge filters are designed, how filtration media actually works, why point-bonded media outperforms traditional materials, and how proper filtration directly impacts water chemistry, customer satisfaction, equipment longevity, and profitability. Whether you're a pool service company, builder, retailer, manufacturer, or simply want to better understand what separates premium filters from inexpensive alternatives, this episode is packed with practical knowledge that will immediately improve the way you think about water quality. In this episode you'll learn: • Why filtration is the foundation of crystal-clear water • How cartridge filters actually work • What "point bonded" filter media means • Why cheap cartridge filters often fail • Injection molded cores vs. PVC cores • Why filter bands matter more than you think • Proper cartridge cleaning techniques • Common mistakes pool professionals make • When filters should actually be replaced • Why turnover rate may be more important than PSI • How engineering decisions impact your customer's pool If you've ever wondered why some pools stay crystal clear while others constantly struggle, this episode explains the science behind it. Episode Timestamps 00:00 Welcome to the Pool Nation Podcast 01:00 Meet Rich Medina from OnCore Filtration 05:45 Rich's engineering background and military experience 12:00 How Rich entered the swimming pool industry 27:00 Building filtration technology through engineering 36:30 Why filtration is the foundation of water quality 44:00 How cartridge filtration actually works 50:00 Filter media explained: point bonded vs. flat bonded 59:45 Injection molded cores vs. PVC cores 1:07:00 Why filter bands matter 1:12:30 The correct way to clean cartridge filters 1:17:00 When should pool filters be replaced? 1:20:00 Creating a maintenance schedule that saves customers money 1:22:00 Why turnover rate matters more than pressure 1:25:00 Final thoughts and takeaways Thank You to Our Visionary Partners A huge thank you to the incredible companies helping us educate and elevate the swimming pool industry. • SPPA • Blue Ray XL • AquaStar Pool Products • Natural Chemistry • Raypak • Heritage Pool Supply • Hayward Pool Products • Encore Brands • Poolside Tech • Pool Brain • Nidec / U.S. Motors • OnCore Filtration Your continued support allows Pool Nation to bring free education to pool professionals across the world.
Interview with Steven Blatt, MD
✅ Hallmarks of Health PodcastFIVE PRIMARY POINTS of the PODCASTHeart Rate Variability (HRV) is a powerful predictor of resilience and longevity.HRV reflects the balance between your sympathetic (”fight or flight”) and parasympathetic (”rest and digest”) nervous systems. Higher HRV is associated with fewer surgical complications, lower inflammation, improved recovery, and reduced risk of death. Consumer devices such as Apple Watch, WHOOP, Fitbit, and Oura can track HRV over time, although values should only be compared within the same device.Four simple habits can improve HRV at little or no cost.The podcast highlights four evidence-based strategies to strengthen your nervous system: practice five deep breaths three to four times daily, engage in meaningful conversation to increase social connection, prioritize high-quality sleep, and exercise consistently. Together these habits increase parasympathetic activity, helping your body better withstand physical and psychological stress.Exercise is nature's peptide therapy.Rather than relying on unproven peptide injections, exercise stimulates muscles to release hundreds of beneficial signaling molecules called myokines. These naturally occurring proteins help regulate inflammation, metabolism, brain function, and muscle growth while promoting long-term health. The podcast argues that regular exercise is a safer, evidence-based alternative to commercially marketed peptide injections.Exercise is powerful medicine, including for cancer prevention and recovery.Emerging research suggests exercise-induced myokines may suppress breast cancer cell growth, while regular exercise is associated with roughly a 20% lower risk of breast cancer recurrence and mortality. The broader message is that exercise should be viewed not only as fitness but also as an effective, low-cost therapy for chronic disease prevention.Breathing is an overlooked foundation of vitality.Consistent deep breathing—particularly cyclic sighing and inspiratory muscle training—can improve lung function, increase HRV, reduce stress, and support healthy oxygen saturation. The podcast recommends treating breathing exercises like brushing your teeth: a simple daily habit that strengthens both physical and mental health while improving resilience over time.Copyright, VyVerse, LLC. All Rights Reserved. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit vitalityexplorers.substack.com/subscribe
Alcohol Injection | Ep 1234 | Crazy Town Podcast
On today's show we reflect on Nottingham Forest's friendly against Blackburn Rovers in Portugal, discuss the latest on Forest's £30m bid to sign Ousmane Diomande from Sporting Lisbon and react to Evangelos Marinakis' latest huge cash injection into the club. Matt Davies is joined by Dan Cook, Simon Bristow and Dillon Mapletoft. #nffc #nottinghamforest
This is the noon All Local for Monday, July 20, 2026
In this series, Going Deep, we’ll be doing bite-sized explorations into the most interesting industries, businesses and economic events… in Australia and around the world. For today's episode, we're diving into the weight loss drug economy - a $58 billion industry built on injections that hack your hunger signal. We've seen food companies scramble to reformulate their products, airlines calculate what lighter passengers mean for their fuel bill and gyms completely rewrite their pitch. In this episode, we'll explore how Ozempic and Wegovy went from diabetes treatments to cultural phenomena…and what a world of meaningfully lighter people actually means for business, public health, and your hip pocket. _ Note: This recording took place in February 2026. All numbers noted were accurate as of this date. Want to lean how to go from a Saver to Investor in just 7 days - watch our new series here Download the free app (App Store): http://bit.ly/FluxAppStore Download the free app (Google Play): http://bit.ly/FluxappGooglePlay Daily newsletter: https://bit.ly/fluxnewsletter Flux on Instagram: http://bit.ly/fluxinsta Flux on TikTok: https://www.tiktok.com/@flux.finance —- The content in this podcast reflects the views and opinions of the hosts, and is intended for personal and not commercial use. We do not represent or endorse the accuracy or reliability of any opinion, statement or other information provided or distributed in these episodes. ____See omnystudio.com/listener for privacy information.
Learn more about Refrigeration Mentor Customized Technical Training Programs at www.refrigerationmentor.com/courses Join the Refrigeration Mentor Hub here This episode is a replay of a recent Refrigeration Mentor Community Meetup where we helped fellow techs with some technical CO2 refrigeration troubleshooting. The live group discussed a problematic CO2 store with high superheat, recurring low-temp oil issues, phase-loss/current-imbalance alarm and others. You'll hear solutions, tips and advice from the fellow techs on the call, including Mikaela Law, Patrick Gregory, Andrew Freeburg, Billy Carlson, Noah Walker, and others. Interested in joining the next meetup? Click here and join our FREE Refrigeration Mentor Hub. In this episode, we cover: (01:39) High Superheat and Injection (03:20) Liquid Line Drop and Flashing (05:14) Pulse Valve Orifice Fix (08:10) Oil Logging (14:41) Pressure Differential and Port Sizing (19:34) HP Valve Failure (23:46) Ice Cream Frost Airflow Hack (26:44) Designing a Custom Divider Prototype (28:39) Selling Value to Customers (32:54) VFD Phase Loss Troubleshooting (35:37) Drive vs Compressor Diagnosis (38:46) Bypass Tests and Amp Imbalance (40:08) Using Bitzer Software Helpful Links & Resources: Episode 378. Field Stories: Compressor Failure, Case Freeze-Up Troubleshooting, and Electrical Safety Episode 360. Get Curious on Service Calls (For Faster Troubleshooting) Episode 382. Why Techs Get Stumped on Supermarket Racks (How To Fix It)
Join Lori and Gideon as they dive into the latest developments in the aesthetic medicine industry. This episode covers recent travel, new neurotoxin updates, top training opportunities, and key industry insights. - News on Boey (botulinum toxin type E): rapid onset, short duration, and its approval status - Practical discussion of pricing, safety, and dosing strategies for neurotoxins - Comparison of toxins: Dysport, Botox, Jeuveau, Letybo, and implications for resistance - Upcoming training events and professional courses for injectors - Tips for safe and effective injection techniques, including the value of anatomy knowledge and proper reconstitution practices _____ 00:00 Using smooth threads in skincare 05:42 Expanding beyond FDA training 12:58 Neurotoxin injection training course 18:43 Medication production and distribution process 23:07 Discussing new botulinum toxin research 28:37 Comparing botulinum toxin types 35:08 Explaining molecular interactions 38:35 Temporary cosmetic procedures for actors 45:53 Choosing neuromodulators for first-timers 49:20 Influencer shares Botox mishap 53:52 Injection technique for facial muscles 01:00:12 Discussing product pricing strategy 01:03:56 End of the show wrap-up
The owners of four injection wells in southeast Ohio's Washington County agreed to voluntarily stop their operations in early July, following a request from the Ohio Department of Natural Resources' oil and gas division.
Two horrific tales of the dangers of plastic surgery! Plus another episode of Baron Void And The Evaders From Venus! [Ep 630]
In this episode, Prof Chapman is joined by a fertility support nurse to explore the gaps in patient care during IVF treatment. They discuss the most common concerns women face — from needle phobia and administering that first injection, to post-egg-collection bleeding and knowing when symptoms warrant escalation. Prof Chapman offers a frank comparison of Australia’s premium versus low-cost IVF clinics, and why patients often absorb only a fraction of what they’re told in consultations — leaving many too embarrassed to ring their clinic with “silly” questions that deserve real answers. Explore the ‘Prof. Michael Chapman – The IVF Journey’ Facebook Page, your reliable destination for cutting-edge insights and guidance within the realm of In Vitro Fertilization (IVF). Don’t miss out on the IVF Journey podcast; stay informed with the latest episode updates. Tune in for expert discussions and valuable information on navigating the intricate path of IVF.
From the sudden retirement of Internet pioneer Vint Cerf to the unstoppable advance of "apex agentic adversaries," get a front-row seat to the unfolding security revolution and its massive real-world stakes. Why Fable5's re-release has disappointed. Opera becomes the first browser to offer "Paste Protect." Microsoft BlueHammer exploit is "hammering" systems. Industry legend (TCP creator) Vint Cerf on AI. Chrome turns 150 with too many fixes to load. Google fails to sidestep a $4.67 billion EU fine. One last (we can hope) Chat Control vote next week. AirDrop & Android Quick Share are exploitable. How to bypass Claude's and ChatGPT's guardrails. My own Sunday spin with SpinRite. A legendary hacker uses AI on a widespread library Show Notes - https://www.grc.com/sn/SN-1086-Notes.pdf Hosts: Steve Gibson and Leo Laporte Download or subscribe to Security Now at https://twit.tv/shows/security-now. You can submit a question to Security Now at the GRC Feedback Page. For 16kbps versions, transcripts, and notes (including fixes), visit Steve's site: grc.com, also the home of the best disk maintenance and recovery utility ever written Spinrite 6. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: blackhat.com/us-26 and use code TWIT cohesity.com/Resilience bitwarden.com/twit zscaler.com/security XBOW.com adaptivesecurity.com
From the sudden retirement of Internet pioneer Vint Cerf to the unstoppable advance of "apex agentic adversaries," get a front-row seat to the unfolding security revolution and its massive real-world stakes. Why Fable5's re-release has disappointed. Opera becomes the first browser to offer "Paste Protect." Microsoft BlueHammer exploit is "hammering" systems. Industry legend (TCP creator) Vint Cerf on AI. Chrome turns 150 with too many fixes to load. Google fails to sidestep a $4.67 billion EU fine. One last (we can hope) Chat Control vote next week. AirDrop & Android Quick Share are exploitable. How to bypass Claude's and ChatGPT's guardrails. My own Sunday spin with SpinRite. A legendary hacker uses AI on a widespread library Show Notes - https://www.grc.com/sn/SN-1086-Notes.pdf Hosts: Steve Gibson and Leo Laporte Download or subscribe to Security Now at https://twit.tv/shows/security-now. You can submit a question to Security Now at the GRC Feedback Page. For 16kbps versions, transcripts, and notes (including fixes), visit Steve's site: grc.com, also the home of the best disk maintenance and recovery utility ever written Spinrite 6. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: blackhat.com/us-26 and use code TWIT cohesity.com/Resilience bitwarden.com/twit zscaler.com/security XBOW.com adaptivesecurity.com
From the sudden retirement of Internet pioneer Vint Cerf to the unstoppable advance of "apex agentic adversaries," get a front-row seat to the unfolding security revolution and its massive real-world stakes. Why Fable5's re-release has disappointed. Opera becomes the first browser to offer "Paste Protect." Microsoft BlueHammer exploit is "hammering" systems. Industry legend (TCP creator) Vint Cerf on AI. Chrome turns 150 with too many fixes to load. Google fails to sidestep a $4.67 billion EU fine. One last (we can hope) Chat Control vote next week. AirDrop & Android Quick Share are exploitable. How to bypass Claude's and ChatGPT's guardrails. My own Sunday spin with SpinRite. A legendary hacker uses AI on a widespread library Show Notes - https://www.grc.com/sn/SN-1086-Notes.pdf Hosts: Steve Gibson and Leo Laporte Download or subscribe to Security Now at https://twit.tv/shows/security-now. You can submit a question to Security Now at the GRC Feedback Page. For 16kbps versions, transcripts, and notes (including fixes), visit Steve's site: grc.com, also the home of the best disk maintenance and recovery utility ever written Spinrite 6. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: blackhat.com/us-26 and use code TWIT cohesity.com/Resilience bitwarden.com/twit zscaler.com/security XBOW.com adaptivesecurity.com
From the sudden retirement of Internet pioneer Vint Cerf to the unstoppable advance of "apex agentic adversaries," get a front-row seat to the unfolding security revolution and its massive real-world stakes. Why Fable5's re-release has disappointed. Opera becomes the first browser to offer "Paste Protect." Microsoft BlueHammer exploit is "hammering" systems. Industry legend (TCP creator) Vint Cerf on AI. Chrome turns 150 with too many fixes to load. Google fails to sidestep a $4.67 billion EU fine. One last (we can hope) Chat Control vote next week. AirDrop & Android Quick Share are exploitable. How to bypass Claude's and ChatGPT's guardrails. My own Sunday spin with SpinRite. A legendary hacker uses AI on a widespread library Show Notes - https://www.grc.com/sn/SN-1086-Notes.pdf Hosts: Steve Gibson and Leo Laporte Download or subscribe to Security Now at https://twit.tv/shows/security-now. You can submit a question to Security Now at the GRC Feedback Page. For 16kbps versions, transcripts, and notes (including fixes), visit Steve's site: grc.com, also the home of the best disk maintenance and recovery utility ever written Spinrite 6. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: blackhat.com/us-26 and use code TWIT cohesity.com/Resilience bitwarden.com/twit zscaler.com/security XBOW.com adaptivesecurity.com
In this episode of Let's Combinate: Drugs + Devices, Subhi Saadeh talks with Julia Anthony, founder and chief strategy officer of Solution Medical, about adrenal crisis, emergency hydrocortisone, and what it takes to build a drug-device combination product from a patient need.Julia was born with salt-wasting congenital adrenal hyperplasia, a life-threatening form of adrenal insufficiency. Because her body cannot make cortisol, she takes cortisol replacement daily and may need an emergency hydrocortisone injection during a crisis.The problem?The current emergency injection can take upto 14 steps to prepare, mix, and administer.Julia explains why the liquid and powder need to stay separate for stability, why the current process is so difficult during an emergency, and how Solution Medical is developing a proprietary dual-chamber primary container to simplify reconstitution while maintaining shelf life without refrigeration.We also discuss how the company evolved from a device idea into a drug-led 505(b)(2) NDA program, the development of a four-step prefilled syringe and two-step auto-injector, human factors testing with both patients and injection-naive users, manufacturing challenges in aseptic processing, supplier trust, regulatory strategy, and the broader platform potential for other mix-before-inject drugs.Chapters00:00 Meet Julia Anthony01:04 Living Without Cortisol02:03 The 14-Step Injection05:01 Building a Combination Product07:54 From Device Concept to Pharma Company10:06 Needles, Steps, and Testing13:25 Patient Insights and Human Factors16:58 Real-World Access Challenges21:50 Why Not a Liquid Formulation?24:15 Regulatory Pathway: 505(b)(2)25:13 Manufacturing and Partner Trust27:32 Rare Disease and Supplier Power31:53 Platform Vision Beyond Adrenal Insufficiency38:05 Reconstitution Is the Hard Part41:12 COVID Tailwinds and Timeline43:38 Where to Find Solution Medical44:42 Final Thoughts on CortisolAbout SubhiSubhi Saadeh is a consultant, trainer, and auditor focused on quality, regulatory, manufacturing, and supplier challenges for drugs, devices, and combination products.Through Let's Combinate, Subhi helps companies navigate the messy intersection of pharmaceutical and medical device requirements through consulting, training, audits, and practical education.He also hosts Let's Combinate: Drugs + Devices, where he speaks with leaders building, regulating, manufacturing, and improving combination products.
Suspected China-Nexus hackers use fake Indian tax filing utility to deploy DcRAT Prompt injection attacks trick AI Agents into making crypto payments France to stop certifying products without quantum-safe encryption Get the show notes here: https://cisoseries.com/cybersecurity-news-india-tax-rat-prompt-injection-crypto-scam-france-pushes-quantum-safe/ Thanks to our episode sponsor, Vanta Your team just added its 67th AI tool. And unfortunately, also your 67th security blind spot. The good news: The Vanta Agent works like a GRC engineer in the background, finding every app your team uses, scoring the risk, and drafting fixes for you. Vanta is the platform used by over sixteen thousand fast-moving companies like Ramp, Cursor, and Harvey who are shaping the future with AI, AND staying ahead of AI risk. Get started at vanta.com/headlines.
PUTF Podcast — Season 4, Episode 6 featuring Barbie Bertisch & Paul RaffaeleLove Injection is variously known as a publication, a radio show, a DJ partnership, production duo, and a record label. Co-founded by Barbie Bertisch and Paul Raffaele in 2015 as a monthly print fanzine, Love Injection's continued multi-faceted expansion and evolution reflects the ongoing process of celebrating people and culture, seeking to fill in the gaps of dance music and nightlife culture's untold stories and histories, and bring new perspectives to familiar ones.The pair host the Love Injection radio show on NYC's beloved online radio institution, The Lot Radio, on the air every Saturday morning since February 2016. This sonic extension of Love Injection the print fanzine provides the duo, and their occasional esteemed guest hosts, the latitude to explore sounds unrestricted by the demands of the nocturnal dance floor. The newest branch of the Love Injection family tree is its record label, Love Injection Records. Conceptually, the label lives and operates with similarly fluid aesthetics, with one foot in the dance world and one outside of it.Counter to the modern trend of increasingly short DJ sets that leave little room for texture and nuance, Barbie and Paul's preferred mode of DJing is the all-nighter – an extended journey/narrative with a beginning, middle, and end. Instagram | www.loveinjection.nyc | Bandcamp | Soundcloud | hi@loveinjection.nyc | Resident Advisor10 Years of Love Injection: A Declaration of Universal Love https://loveinjection-nyc.bandcamp.com/album/10-years-of-love-injection-a-declaration-of-universal-love-compiled-by-barbie-bertisch-paul-raffaelePUTF's interview series is dedicated to spotlighting inspiring creatives from the PUTF community and beyond. Guests share their unique career journeys, stories, and visions.Pick Up The Flow, is an online resource based in NYC striving to democratize access to opportunities. Opportunities are shared daily on this page and website, and weekly via our newsletter.Newsletter: https://putf.substack.comInstagram: https://www.instagram.com/pickuptheflownyc/Youtube: https://www.youtube.com/@pickuptheflow#loveinjection #nyc #music #community #nycculture #zine #radio #barbiebertisch #paulraffaeleJoin the newsletter: https://putf.substack.com/and follow us on Instagram: https://www.instagram.com/pickuptheflownyc/ Hosted on Acast. See acast.com/privacy for more information.
In this episode, learn how to generate 1K with one sale, using passive income and then put it on repeat. Email me: support@brooklynstorme.com anytime with questions or for help with your business
Could something as simple as a 20-minute bike ride improve the quality of platelet-rich plasma?In this episode of Overtime with The Sports Docs, Drs. Ashley Bassett and Catherine Logan explore an intriguing laboratory study examining whether exercise performed immediately before a PRP blood draw can enhance the cellular composition of platelet-rich plasma.As biologic therapies continue to expand throughout sports medicine, optimizing PRP has become increasingly important. While most discussions focus on centrifuge systems, platelet concentrations, leukocyte content, and injection techniques, this study introduces another potential variable: the patient.The authors found that a brief bout of vigorous exercise significantly increased platelet concentrations and mobilized hematopoietic progenitor cells, raising the possibility that exercise could serve as a simple, low-cost strategy to optimize biologic treatments.In This Episode, We Discuss: The fundamentals of PRP and how it works Why PRP variability remains one of the biggest challenges in interpreting the literature Conditions with the strongest evidence supporting PRP: Knee osteoarthritis Lateral epicondylitis Patellar tendinopathy Plantar fasciitis The concept of exercise-mobilized PRP Differences between plasma-based and buffy coat PRP systems Whether higher platelet concentrations actually translate into improved clinical outcomes How this research may influence real-world PRP protocols Study BreakdownStudy Design: Prospective laboratory studyParticipants: 20 healthy volunteers (ages 21–45 years)Exercise Protocol: 5-minute warm-up 20 minutes of cycling Target heart rate: 70–85% of predicted maximum Blood samples were obtained before and immediately after exercise and processed using two PRP systems:ACP System (plasma-based PRP) Angel System (buffy coat PRP) Key FindingsWhole Blood Changes After Exercise Platelet count increased approximately 22% White blood cell count increased approximately 50%ACP System Platelet concentration increased from approximately: 457,000/µL → 562,000/µLAngel System Platelet concentration increased from approximately: 2.95 million/µL → 3.77 million/µL PRP volume increased Hematopoietic progenitor cell concentrations increased significantly Why This MattersThe study suggests that patient physiology before blood collection may significantly influence the final biologic product.A brief exercise session may: Increase platelet yield Mobilize progenitor cells Potentially enhance biologic activity Provide a low-cost method to optimize PRP preparation For clinicians performing biologic injections, exercise may become another controllable variable alongside: PRP preparation system Centrifuge settings Leukocyte concentration Injection technique Clinical Pearls✔ PRP is not a single product. Composition varies substantially between systems.✔ Patient factors may influence PRP quality just as much as centrifuge settings.✔ Twenty minutes of exercise increased platelet concentrations in both PRP systems.✔ Buffy coat systems demonstrated increased progenitor cell concentrations.✔ The clinical significance of these changes remains unknown.The Big QuestionDoes exercise-enhanced PRP actually improve patient outcomes?This study demonstrates changes in laboratory measurements, but it does not tell us whether patients: Heal faster Experience less pain Return to sport sooner Demonstrate better tendon or cartilage healing Future studies are needed to determine: Optimal exercise type Ideal exercise intensity Timing before blood draw Which conditions benefit most Dr. Logan's Clinical PerspectiveAt the Joint Preservation Center, this study has prompted discussions about incorporating pre-injection exercise into PRP protocols. A simple 20-minute cycling session before blood collection may represent a practical strategy to optimize a patient's own biology before treatment.While additional evidence is needed, this concept aligns with the broader goal of maximizing the effectiveness of biologic therapies through thoughtful patient preparation.Take-Home Points Exercise before PRP collection significantly increases platelet concentrations. Short bouts of exercise may mobilize progenitor cells. Patient physiology may influence PRP composition. Exercise represents a low-cost, non-pharmacologic optimization strategy. More research is needed to determine whether these laboratory changes improve clinical outcomes. Resources Mentioned Episode #161: Platelet concentration and outcomes following PRP for lateral epicondylitis Recent Sports Docs episode with Dr. Arianna Gianakos discussing PRP for plantar fasciitis
A lesson in universal love, told via deep club grooves. When future heads look back at New York nightlife from the mid-2010s onwards, the name Love Injection will stand out. As historians, stewards and disciples of underground dance music, Barbie Bertisch and Paul Raffaele live and breathe the culture's inclusive, anti-commercial and anti-egotistical ideals. Underlining their myriad pursuits–DJing, promoting, publishing, curation, the list goes on–are ironclad principles destined to cement their legacy. On RA.1044, the duo keep it real. Recorded spontaneously, it shows off their core palette: timeless Detroit house courtesy of Scott Grooves, leftfield 303 squelches from Magic Mountain High, the classic dub techno of Rhythm & Sound and plenty more besides. It's a living history of Love Injection, delivered with their signature level of passion and care. Find the tracklist and Q&A at ra.co/podcast/1063
Jonathan Rodriguez Cefalu built the hardware that Snap shipped on people's faces — first the camera-only Gen 1 Spectacles, then the Gen 4 display version. His path through Stanford CS, an honors thesis on varifocal display optics, and a startup called Vergence (named after the vergence-accommodation conflict in AR) led him to Snap, and then to the problem he is working on now. Preamble AI exists to prevent the worst possible AI outcomes — starting with a class of attack that Preamble was the first to publicly demonstrate: prompt injection.Ted Schilowitz hosted this episode solo. Together, he and Jonathan worked through the architecture problem sitting under every AI assistant being deployed at scale right now: large language models see one token stream. There is no separation between what the developer intended and what an untrusted email or web page is quietly instructing the model to do. With Gemini Spark about to give AI agents access to tens of thousands of emails per user, this is not a theoretical concern. Jonathan's team has a proposed fix — and they have already shaped federal law.The episode also covered the week's XR and AI news: Google I/O announcements, Snap Spectacles Gen 6 details ahead of AWE, Matthew Ball joining Xbox, Anduril's battlefield AR wearable, and AI-generated feature films reaching Tribeca.Key Moments:[00:00] Ted opens solo — Charlie Fink and Rony Abovitz are out for the summer solstice[02:30] Google I/O: Gemini Spark and what "persistent AI agent" actually means in practice[08:15] Jonathan's Gmail test: asked to search tens of thousands of emails, it searched 30 and quit[14:40] XREAL Project Aura and the state of Android XR — a lot of spend for incremental steps[21:00] Snap Spectacles Gen 6 details: what Jonathan knows from building Gen 1 and Gen 4 from the inside[31:20] Snap vs. Meta: research that ships in the product vs. research that ships in a paper[38:45] Matthew Ball joins Xbox, Anduril EagleEyes, and battlefield AR wearables[44:10] AI on the Lot: Project Nara, Hell Grind, Dreams of Violet, Paul Schrader goes pro-AI[52:30] Jonathan introduces Preamble AI and the mission to prevent worst-case AI outcomes[58:00] The first public demonstration of prompt injection — what happened and why it matters[01:06:15] Why Gemini Spark will be especially vulnerable to prompt injection attacks[01:14:00] Preamble's proposed fix: a reserved token language that untrusted data cannot speak[01:21:30] NDAA Section 1638: the first US law making it illegal to give AI autonomous nuclear control[01:28:45] WarGames, "the only winning move is not to play," and what that means in 2026Brought to you by Zappar and Mattercraft. Mattercraft makes spatial web experiences that run in the browser — no app required. Visit mattercraft.io to learn more and start building. Hosted on Acast. See acast.com/privacy for more information.
Il y a une semaine, l'Afrique du Sud lançait officiellement le lénacapavir, un antirétroviral utilisé dans le traitement de l'infection par le VIH, jugé révolutionnaire. Avec une seule injection tous les six mois, ce médicament préventif atteint une efficacité qui frôle les 100%. « Un signe d'espoir » s'est réjoui Cyril Ramaphosa, président du pays le plus touché au monde par le VIH, avec plus d'un Sud-Africain sur dix porteurs du virus. Un signe d'espoir également pour toute l'Afrique, qui concentrait, en 2024, 65% des personnes vivant avec le VIH dans le monde, selon les données d'Onusida. La Camerounaise Ndong Essomba Bitchoka, infectiologue à l'unité de prise en charge des patients VIH/SIDA à l'hôpital de Deido, à Douala explique ce que ce traitement peut changer. RFI : Les Sud-Africains porteurs du VIH peuvent désormais bénéficier du nouveau traitement Lenacapavir. Pourriez-vous expliquer comment fonctionne ce traitement ? Dr Ndong Essomba Bitchoka : Le Lenacapavir est un médicament antirétroviral. Il va empêcher l'assemblage des molécules ARN du virus du VIH, donc empêcher la formation de nouveaux virus du VIH. C'est à peu près comme ça qu'il fonctionne. Pour simplifier un peu, quelle est la grande avancée du Lenacapavir par rapport à la PrEP, le traitement le plus couramment utilisé ? La PrEP est un médicament qu'on va administrer aux personnes non-infectées au VIH pour leur éviter de le contracter. Il est beaucoup plus indiqué pour les personnes qui sont plus à risque de développer le VIH. Le Lenacapavir, par contre, peut être utilisé dans le traitement de l'infection au VIH pour contrôler le virus chez certaines personnes. C'est-à-dire qu'au lieu de prendre des comprimés tous les jours par exemple, vous allez avoir des injections qui vont permettre de limiter la réplication du virus dans votre organisme pendant environ six mois. Donc la PrEP est destinée à titre préventif aux personnes non-porteuses du VIH, tandis que le Lenacapavir peut aussi être un traitement pour les personnes porteuses. Et sa grande différence est qu'au lieu de comprimés, on donne des injections deux fois par an… Exactement ! La personne doit déjà au préalable être contrôlée avec des médicaments oraux, avec des comprimés. Puis le Lenacapavir vient appuyer l'action des antirétroviraux qui étaient déjà présents à la base, qui contrôlaient le virus. Sauf que ce même contrôle va se faire sur une longue durée d'action associée à d'autres médicaments. Donc le Lenacapavir pour une personne déjà porteuse du VIH, il faut déjà qu'il y ait un traitement antérieur au Lenacapavir ? C'est cela. Si on a un patient qui est dépisté séropositif au VIH aujourd'hui, le Lenacapavir ne sera pas la première intention qu'on pourra lui proposer en termes de traitement. Hormis l'Afrique du Sud qui cumule le plus grand nombre de personnes atteintes du VIH dans le monde (8 millions de Sud-Africains, NDLR), une grande partie des infectés vivent en Afrique. Vous avez une estimation du coût du traitement ? Comme je n'ai pas le coût exact, je ne pourrai pas vous donner une réponse exacte. Mais dans la majorité des cas, si je parle par exemple de mon pays, le Cameroun, le Lenacapavir n'est pas encore accessible par exemple. Mais pour l'instant, les États avec les partenaires financiers font le nécessaire pour que les médicaments soient subventionnés. Du coup, les patients ne les paient pas. Dans le cas de l'Afrique du Sud, je ne sais pas encore si ce sera le cas ou pas, mais je pense que les États se battent pour voir dans quelle mesure subventionner, ne serait-ce qu'en partie, l'accès à ces médicaments antirétroviraux. Pour l'instant, seules 40 000 doses ont été mises à disposition en Afrique du Sud. Le président Cyril Ramaphosa annonce la fourniture d'un million de doses d'ici fin 2027. Sauf que l'organisation Health Gap estime qu'il en faudrait le double de ces doses chaque année pour répondre aux besoins du pays. Au-delà du cas sud-africain, une pénurie plongerait-elle les patients bénéficiaires dans un nouveau désarroi ? Quelles seraient les conséquences s'ils étaient forcés de suspendre le traitement ? C'est bien de pouvoir commencer avec un certain nombre de doses et de sélectionner les patients qui sont vraiment nécessiteux par rapport à ce traitement au Lenacapavir. En fonction de comment la réponse à ce traitement se fera chez ces patients, on pourrait envisager d'augmenter le nombre de doses disponibles et même d'augmenter la population qui pourrait y avoir accès. Le risque, effectivement, c'est qu'en disponibilisant beaucoup de doses de médicaments et qu'après l'Etat ne puisse plus s'en procurer, ça va effectivement créer une rupture dans le traitement et la survenue de résistance à cet antirétroviral, qui est plutôt salutaire pour la prise en charge des patients. On rappelle que le Lenacapavir n'est pas un vaccin. Pourquoi y a-t-il plus de recherches sur le traitement plutôt que sur un vaccin ? Est-ce si compliqué à élaborer ? Le VIH est un virus qui est un petit peu sournois, dans le sens où il a beaucoup de mutations. Imaginez un cambrioleur qui visite différentes maisons, mais avec un mode opératoire différent. Il est identifié comme mesurant 1m80 quand il frappe dans la maison A, mais quand il va dans la maison B, il mesure plutôt 1m50. Ce qui lui permet d'entrer dans certaines ouvertures inaccessible pour un cambrioleur de 1m80. Il y a beaucoup de mutations. On n'arrive pas encore à identifier un vaccin qui pourrait bloquer l'action de ces différentes souches mutantes du VIH. C'est ce qui rend la chose difficile pour trouver un vaccin. Mais il y a quand même des essais qui donnent un petit peu espoir. Notamment l'essai BRILLIANT 011 en cours justement en Afrique du Sud, pour lequel on espère avoir de bons résultats d'ici quelques années.
DianeKazer.com/SPOOKY2 --> CHIMINISTRY 5% Off Join Our Root Cause Reset Beginning June 18 --> DianeKazer.com/RCR Join Our Elite VIP Tribe for Peptide & Bioregulator Support + Live Q&A -->DianeKazer.com/VIP Apply to Become a One-on-One Patient --> DianeKazer.com/PATIENT SHOW LINKS: https://www.spooky2-mall.com/peptide-presets-revolutionizing-healing-at-the-molecular-level/ https://www.spooky2reviews.com/ https://www.spooky2reviews.com/browse-by-disease/ What if one of the most powerful healing tools isn't a supplement, medication or expensive treatment... But a simple and affordable device you use at home, or anywhere? Over the past year, I've been using a healing tool from home that has completely changed the way I think about supporting the body. It's become an integral part of my own wellness routine, and after receiving so many questions from our community, I decided it was time to bring in expert Spooky2 Trainer, Jon Ellis, to discuss a technology that has developed a passionate following among those looking for natural ways to support their health. During this eye-opening conversation, we'll cover:
In episode 323 of Absolute AppSec, co-hosts Ken Johnson and Seth Law focus heavily on core application security vulnerabilities, legacy operational struggles, and the challenges of generative AI systems. After briefly discussing Seth's recent trip to BSides Vancouver and confirming upcoming conference training logistics for Black Hat and DEF CON, the duo dives into the persistent problem of secrets and sensitive data leaking into log files. Referencing an article and talk by Alan Reyes, they unpack the compounding nature of logging failures, noting how system-level integrations and production error conditions often dump entire object blocks or environment variables into third-party tools. They caution that while pattern-based scanners exist, they remain too brittle to capture complex edge cases, and utilizing expensive AI agents to screen every real-time log line is economically impractical. Transitioning to AI security, Seth explores a multi-page research paper analyzing prompt injection. The paper establishes that because large language models mathematically process data through tokenization without any physical or architectural separation between instructions and data contexts, prompt injection cannot be completely solved at the model level. Likening prompt injection to automated social engineering, they argue that the onus currently falls entirely on developers to implement deterministic validation, guardrails, and secure application-level harnesses.
(2) Bob Zimmerman details the December 21, 1968, launch and the historic trans-lunar injection that sent humans toward another planet for the first time. Zimmerman describes the Saturn 5 ride as surprisingly smooth compared to Gemini rockets, despite the primitive onboard computers that required manual data entry of long number strings. He shares Jim Lovell's perspective of the Earth shrinking until the entire Atlantic could be covered by a thumb. Crucially, the discussion reveals that while the Space Race remained competitive, NASA was unaware that Soviet Zond failures had secretly forced the cancellation of their own manned mission.1939
(7) Bob Zimmerman describes how the mission's return depended on a high-stakes Trans-Earth Injection burn, after which Jim Lovell famously radioed that "there is a Santa Claus." Zimmerman describes a navigation crisis where Lovellaccidentally wiped the computer's orientation data, forcing him to use a sextant and stars—ancient naval tools—to manually realign the ship. The guest marvels at the "double skip" re-entry, where the capsule bounced off the atmosphere at 25,000 miles per hour to slow down. Despite turning upside down in the Pacific, the crew returned safely, fulfilling a mission with odds NASA originally pegged at only 50/50.1959
Brady Hicks, WCW's Maestro, and Kathie Fitz take calls and talk the latest news. Live, Tuesday nights at 7:30PM ET on vocnation.com, it's IN THE ROOM! ITR features topics introduced by the panel, your calls, PWI's Brady Hicks, Kathie Fitz, and WCW's Maestro. Visit http://vocnation.com. Full Video Episode Available for only $3/mo at www.vocnation.com! Subscribers also get commercial free audio and video of Wrestling with History featuring Bill Apter and Ken Resnick, In the Room featuring PWI's Brady Hicks and former WCW Star the Maestro, No BS with The Bull Manny Fernandez, and more! VOC Nation takes you behind the scenes of your favorite moments in pro wrestling history. Notable show hosts include legendary pro wrestling journalist Bill Apter, former WWE/TNA star Shelly Martinez, former WWE and AWA broadcaster Ken Resnick, former WCW performer The Maestro, former TNA Impact talent Wes Brisco, Pro Wrestling Illustrated's Brady Hicks, independent pro wrestling and Fireball Run star Sassy Stephie, and more! Since 2010, VOC Nation has brought listeners into the minds of the biggest stars in pro wrestling and entertainment. Subscribe to the podcasts for free on most major directories, and visit http://vocnation.com for live programming. Subscribe to premium - only $3/mo - for commercial full commercial free audio and video episodes. Exclusive access to 50 years of Bill Apter's interview archives is available for a nominal charge. Learn more about your ad choices. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Please see https://www.pfi.sr/HYMPAVZI_PI for Full PI #HYMPAVZISponsored William S. Somers, Ph.D. is a biotherapeutics research and development leader with more than 30 years of experience across biotechnology and pharmaceutical organizations, including Pfizer. As a scientist living with hemophilia, Dr. Somers played a key role in driving the patient-centric and purposeful design of HYMPAVZI (marstacimab-hncq). This episode will explore how the patient perspective influenced the scientific journey, with a special focus on Will's research and why it was personally important for him to bring HYMPAVZI to people with hemophilia. To learn more and for safety information, visit HYMPAVZI.com. This post is directed to a U.S. audience and may not be suitable outside of the U.S. This video is intended to be viewed as it was originally produced in partnership with Pfizer. Remember, this content is for educational purposes only and is not intended to replace discussions with a healthcare provider. PP-HYM-USA-1071 Show Notes: For prescribing information visit pfi.sr/HYMPAVZI_PI For information on how to navigate your treatment journey visit the shared decision-making guide here. Listen and subscribe where you get your podcasts! #Hemophilia HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use HYMPAVZI safely and effectively. See full prescribing information for HYMPAVZI. HYMPAVZI (marstacimab-hncq) injection, for subcutaneous use Initial U.S. Approval: 2024 INDICATIONS AND USAGE HYMPAVZI is a tissue factor pathway inhibitor (TFPI) antagonist indicated for routine prophylaxis to prevent or reduce the frequency of bleeding episodes in adult and pediatric patients 12 years of age and older with: hemophilia A (congenital factor VIII deficiency) without factor VIII inhibitors, or hemophilia B (congenital factor IX deficiency) without factor IX inhibitors. DOSAGE AND ADMINISTRATION See Full Prescribing Information for important dosing and administration instructions. The recommended dosage of HYMPAVZI is: Loading dose: 300 mg (two 150 mg injections) by subcutaneous injection Maintenance dose: One week after the loading dose, initiate maintenance dosing of 150 mg every week by subcutaneous injection on the same day each week, at any time of day. Dose adjustment to 300 mg subcutaneous injection weekly can be considered. Factor VIII and factor IX products can be administered for the treatment of breakthrough bleeds in patients receiving HYMPAVZI. Do not use additional doses of HYMPAVZI to treat breakthrough bleeds. Temporarily discontinue HYMPAVZI before major surgery. DOSAGE FORMS AND STRENGTHS Injection: 150 mg/mL in a single-dose prefilled syringe Injection: 150 mg/mL in a single-dose prefilled pen CONTRAINDICATIONS None. WARNINGS AND PRECAUTIONS Thromboembolic Events: Thromboembolic events may occur. Interrupt HYMPAVZI prophylaxis if symptoms occur. Hypersensitivity: Hypersensitivity reactions may occur. In the event of a severe allergic reaction, discontinue HYMPAVZI. Embryofetal Toxicity: May cause fetal harm. Advise females of reproductive potential of the potential risk to the fetus and to use effective contraception. ADVERSE REACTIONS Adverse reactions reported in ≥3% of HYMPAVZI-treated patients were injection site reaction, headache, and pruritus. To report SUSPECTED ADVERSE REACTIONS, contact Pfizer Inc. at 1-800-438-1985 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling. Revised: 12/2025
Talk Python To Me - Python conversations for passionate developers
The OWASP Top 10 just got a fresh update, and there are some big changes: supply chain attacks, exceptional condition handling, and more. Tanya Janca is back on Talk Python to walk us through every single one of them. And we're not just talking theory, we're going to turn Claude Code loose on a real open source project and see what it finds. Let's do it. Episode sponsors Temporal Talk Python Courses Links from the show DevSec Station Podcast: www.devsecstation.com SheHacksPurple Newsletter: newsletter.shehackspurple.ca owasp.org: owasp.org owasp.org/Top10/2025: owasp.org from here: github.com Kinto: github.com A01:2025 - Broken Access Control: owasp.org A02:2025 - SecuA02 Security Misconfiguration: owasp.org ASP.NET: ASP.NET A03:2025 - Software Supply Chain Failures: owasp.org A04:2025 - Cryptographic Failures: owasp.org A05:2025 - Injection: owasp.org A06:2025 - Insecure Design: owasp.org A07:2025 - Authentication Failures: owasp.org A08:2025 - Software or Data Integrity Failures: owasp.org A09:2025 - Security Logging and Alerting Failures: owasp.org A10 Mishandling of Exceptional Conditions: owasp.org https://github.com/KeygraphHQ/shannon: github.com anthropic.com/news/mozilla-firefox-security: www.anthropic.com generalpurpose.com/the-distillation/claude-mythos-what-it-means-for-your-business: www.generalpurpose.com Python Example Concepts: blobs.talkpython.fm Watch this episode on YouTube: youtube.com Episode #545 deep-dive: talkpython.fm/545 Episode transcripts: talkpython.fm Theme Song: Developer Rap
2. Zimmerman details the December 1968 launch and the historic trans-lunar injection. He describes the crew's reliance on primitive computers, requiring manual data entry for critical maneuvers. As they accelerated toward the moon, Jim Lovell observed the Earth shrinking, marking humanity's first departure from Earth orbit. (2)1870