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The Interdisciplinary Meeting of Antimicrobial Resistance and Innovation has launched! The first version of IMARI brought together researchers, clinicians, industry leaders and policymakers to address one of the greatest challenges in modern medicine: antimicrobial resistance" Check the highlights at IMARI.org and prepare for IMARI 2017 from January 27-29, 2027! The inaugural amazing conference took place in Las Vegas. This is the forst time that ASM and IDSA collaborate together in a scientific meeting. One of the sessions involved an unprecedent collaboration between two journals AAC and JID published by each society. To celebrate this achievement we had a session of the best AMR papers of 2025 for AAC and JID. This session will be presented here as apart of our series. Watch this episode: https://youtu.be/XRYl7863z34 Objectives: - Review the best papers and topics of AMR in 2025 form AAC and JID. - Discuss the context of each finding and contributions to the AMR community - Elaborate on the implications for AMR, novelties and how the field is advancing. Guests: - Ayesha Khan, Ph.D. Assistant Professor, Pathology & Laboratory Medicine and Associate Director, Division of Clinical Microbiology Biomedical & Translational Research Track. Principal Investigator, UC3P UCI Prime Pre-Health Pathways Program. - Madison Stellfox, M.D. Ph.D. Assistant Professor of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA. Links: Links: AAC A microbiological and structural analysis of the interplay between sulbactam/durlobactam and imipenem against penicillin-binding proteins (PBPs) of Acinetobacter spp. https://doi.org/10.1128/aac.01627-24 JID Ampicillin/Sulbactam in Combination with Ceftazidime/Avibactam Against Metallo-β-Lactamase-Producing Carbapenem-Resistant Acinetobacter baumannii: A Genomics-Informed Mechanism-based model https://doi.org/10.1093/infdis/jiaf567 AAC Advancements in the fight against globally distributed OXA-48 carbapenemase: evaluating the new generation of carbapenemase inhibitors https://doi.org/10.1128/aac.01614-24 JID Daptomycin-Loaded Nanocarriers Facilitate Synergistic Killing of Methicillin-Resistant Staphylococcus aureus via Lipid-Mediated Interactions and Targeting https://doi.org/10.1093/infdis/jiaf492 AAC Amoxicillin-non-susceptible Streptococcus pneumoniae causing invasive pneumonia: serotypes, clones, and clinical impact https://doi.org/10.1128/aac.00237-25 JID Blood Cultures Contain Populations of Genetically Diverse Candida albicans Strains that May Differ in Echinocandin Tolerance and Fitness https://doi.org/10.1093/infdis/jiaf495 AAC Antibiofilm activity of manogepix, ibrexafungerp, amphotericin B, rezafungin, and caspofungin against Candida spp. biofilms of reference and clinical strains https://doi.org/10.1128/aac.00137-25 JID Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates https://doi.org/10.1093/infdis/jiae438 AAC Emergence of antibiotic-specific Mycobacterium tuberculosis phenotypes during prolonged treatment of mice https://doi.org/10.1128/aac.01310-24 JID The Changing Paradigm in Infectious Diseases—Host-Directed Medicine: Implications for the Next Generation of ID Physicians https://doi.org/10.1093/infdis/jiaf497 JID Triggering Toll-Like Receptor 5 Signaling During Pneumococcal Superinfection Prevents the Selection of Antibiotic Resistance https://doi.org/10.1093/infdis/jiae239 IMARI Conference This episode is brought to you by the Antimicrobial Agents and Chemotherapy journal available at https://asm.org/aac. If you plan to publish in AAC, ASM Members get up to 50% off publishing fees. Visit https://asm.org/joinasm to sign up. Visit https://asm.org/aac to browse issues and/or submit a manuscript. Follow Cesar on twitter at https://twitter.com/SuperBugDoc for AAC updates.
This week's episode features an interview with Dr. Jeniffer Dien Bard and Dr. Amy Leber. Dr. Dien Bard is the Director of Microbiology at the Children's Hospital in Los Angeles, California. Dr. Leber works at the Department of Pathology Laboratory Medicine at Nationwide Children's Hospital in Columbus, Ohio. They join the podcast this week to talk about the shortages of Clinical Medical Laboratory Professionals in Microbiology. Why do we have these shortages? What about training programs? How long does training a professional takes? Tune in to this episode to find out. Link to original article: https://doi.org/10.1128/jcm.00241-22Link to certification for laboratory personnel: https://www.ascp.org/content/board-of-certification/get-credentialedLink for accredited programs: https://www.naacls.org/Find-a-Program.aspx
Mary has a fascinating conversation with Dr. Liz Head, Professor, Vice Chair for Research in the Department of Pathology & Laboratory Medicine at the University of California - Irvine, about research into people with Down syndrome and Alzheimers. Canadian Clinical Trials United States Clinical Trials
In this segment, Beyond the Scope, we speak to pathologists about their pursuits and interests outside of pathology. How can pathologists "get out of the basement"? How can getting IN the basement be a good thing? What does being a Chair have to do with camels? How can YOU help shape the next edition of the Paris System? On this episode of Beyond the Scope, Dr. Sara Jiang (@Sara_Jiang) speaks with Dr. Eva_Wojcik (@Eva_Wojcik), Chair of Pathology & Laboratory Medicine at Loyola University in Chicago, Past President, American Society of Cytopathology, and Founding Chair of the Paris System for Reporting Urinary Cytopathology. Don't forget to fill out the Paris Survey! Cover art: Dr. Eva Wojcik. Featured public domain music: US Army Blues, BugaBlue
Author: Rachel Beham, PharmD Educational Pearls: Some synthetic cannabinoids have been contaminated with Brodifacoum. Brodifacoum is a Vitamin K antagonist and can present with a severe coagulopathy. Brodifacoum is commonly known as “superwarfarin” and has a very long half life of 120+ days. Check PT/INR in patients with a bleeding diathesis in setting of synthetic cannabinoid use. Treatment is activated charcoal and large doses of Vitamin K (10mg Q6H for months). References: Lipton R.A.; Klass E.M. (1984). "Human ingestion of a 'superwarfarin' rodenticide resulting in a prolonged anticoagulant effect". JAMA. 252: 3004–3005. La Rosa F; Clarke S; Lefkowitz J. B. (1997). "Brodifacoum intoxication with marijuana smoking". Archives of Pathology & Laboratory Medicine. 121: 67–69
Dr. Roy Nambudripad completed his undergraduate and medical school education at the University of California at Irvine. He then completed a four-year residency in surgical and clinical pathology at UC Irvine Medical Center, which is the field focused on medical and surgical diagnosis. Subsequently, Roy spent a year training and getting certified in medical acupuncture through the UCLA/Stanford program under the tutelage of Joseph Helms, MD. He is a member of the American Academy of Medical Acupuncture as well as the Director of Research for the NAR Foundation, an organization focused on researching forms of non-conventional allergy treatment. In addition, he spent many years training in NAET with his world-renowned mother, Dr. Devi. He specializes in NAET and medical acupuncture. His publications have appeared in peer-reviewed medical journals such as Circulation, International Journal of Surgical Pathology, Archives of Pathology & Laboratory Medicine, and Global Advances in Health & Medicine. In addition, he has presented his research in medicine at professional society meetings and given international talks on NAET. Roy enjoys spending time with his family and is also studying for law school which he hopes to complete in 2017. For more information, visit www.naet.com or www.oc-integrative-medicine.com.
Intalere welcomes Peter H Gilligan PhD Professor of Microbiology-Immunology and Pathology-Laboratory Medicine at the University of North Carolina School of Medicine and the Director of the Clinical Microbiology-Immunology Laboratories at the University of North Carolina Hospitals, for a discussion on Clostridium difficile. Dr. Gilligan will address risk factor for CDiff, who should be tested for CDiff, carriers of CDiff and CDiff as a Hospital Acquired Infection.
Dr. Larry Kaskel welcomes Dr. Evan Stein to Lipid Luminations. Dr. Stein is Professor of Pathology/Laboratory Medicine and Associate Professor of Internal Medicine at the University of Cincinnati. In 1972 Dr. Stein formed the first Lipid Clinic in South Africa. He will be enlightening us about subfractions and how, why and if we should be paying attention to the.