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In this high-impact solo episode, Darin strips away the noise, hacks, and hype to deliver a clear, no-BS roadmap for transforming your body, brain, energy, and direction in life. This is a straight-talk breakdown of the 5 foundational habits that matter most — the habits backed by science, ancient wisdom, and Darin's decades-long experience living this work every day. Expect practical steps, micro-experiments, timing rules, and the mindset needed to reclaim sovereignty in a world full of distraction. If you're ready to build a stronger, clearer, more powerful version of yourself… this is the episode. What You'll Learn 00:00 – Welcome to SuperLife How this podcast helps you build sovereignty through real habits, real truth, and real practices. 03:07 – Why this episode is different Darin lays out the mission: habits, hacks, hard truths — without dogma or fluff. 03:44 – The 5 foundational moves that change your biology A preview of the metabolic, physical, mental, and behavioral levers that create huge shifts. 1. METABOLIC EDGE — Eat Like You're Building a Future 04:03 – Terrain theory + why your food timing matters How altering the internal environment of your cells changes everything. 05:02 – The two levers that unlock metabolic health Time-restricted eating + plant-forward whole foods. 05:23 – Compressing your eating window Why 8–10 hours is ideal, how it improves glucose, insulin, weight, and inflammation. 06:18 – Practical weekly ramp-up Week 1: 12 hours. Week 2: 8–10 hours. Simple, sustainable, achievable. 07:10 – Darin's personal eating window 10 a.m. to 6 p.m. — and why eating earlier aligns with digestive fire. 2. MOVEMENT THAT MATTERS — Strength Is Survival 11:04 – Why strength training is non-negotiable Muscle protects metabolism, bone density, insulin sensitivity, and longevity. 11:51 – What the evidence says Huge cohort studies show strength training reduces all-cause mortality. 12:23 – The perfect weekly formula 3x/week compound lifts + daily movement + micro-bursts every hour. 13:06 – Real-life practicality Darin's routine of walking, sprinting dogs, mountain biking, and breaking up the day with movement. 3. SLEEP — The Ultimate Biological Reset 16:26 – The truth everyone ignores You cannot out-supplement or out-biohack poor sleep. 16:40 – The real impact of chronic sleep loss Cognition, memory, hormones, emotional regulation — all decline. 17:37 – The universal rule: consistent timing Same bedtime ± 30 minutes, every night. 17:52 – 60-minute wind-down protocol Screens off, light down, nervous system softening. 18:32 – Using sauna as a down-regulation tool Infrared benefits + why Darin does it twice a day in winter. 4. MINDSET & CONSCIOUSNESS — Your Attention Is Your Power 20:00 – Why optimization fails without attention training You can master food, workouts, and sleep — but scattered attention destroys progress. 20:48 – Darin's morning protocol Water → elixir → infrared pad → meditation → visualization → journaling. Every day. Everywhere. 21:01 – Meta-analysis proof Meditation reduces anxiety, depression, stress — and rewires your brain. 21:23 – The perfect 10-minute breathwork formula 5–5–5–5 or 4–4–4–4 cycles for nervous system reset. 21:56 – Journaling as medicine Stream-of-consciousness to activate clarity and emotional release. 5. WEALTH — Treat Your Time Like Capital 22:36 – Redefining wealth It's not money — it's your magnetism, output, relationships, and purpose. 23:16 – The compounding effect of tiny decisions Time batching, micro-actions, and protecting your attention from the social media attention economy. 24:02 – Mini productivity framework 90 seconds → 3 important calls. Every Friday → 1 paragraph on what scaled this week. 25:14 – Darin's post-meditation rule No scrolling — replace with proactive actions: reading, outreach, Patreon replies. FINAL TAKEAWAYS 26:02 – The master checklist: • Time-restricted eating • Plant-focused meals • Resistance training • Daily meditation • Consistent sleep • Sauna recovery • Treating time like capital 26:11 – The real danger Chasing hacks before mastering fundamentals leads to burnout, confusion, and stress. 27:58 – Your power is in the basics These are simple, accessible, and life-changing. 28:04 – Closing message "Have your best Super Life Day ever." Thank You to Our Sponsors Our Place: Toxic-free, durable cookware that supports healthy cooking. Go to their website at fromourplace.com/darin and get 35% off sitewide in their largest sale of the year. Manna Vitality: Go to mannavitality.com/ and use code DARIN12 for 12% off your order. Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences Key Takeaway "Your biology changes when your decisions change. Nail your sleep, nail your strength, honor your attention, and treat your time like capital — and you will build a Super Life from the ground up." Bibliography Time-restricted eating (human RCTs / reviews) — Wilkinson et al., 10-hour TRE reduced weight and improved cardiometabolic markers (2019). PMC Intermittent fasting / metabolic health review — comprehensive reviews showing metabolic switching benefits. PMC+1 Plant-forward/vegetarian diets & cardiometabolic outcomes — BMJ/Nutrition reviews and JAMA network evidence showing improved CVD risk markers and metabolic benefits. BMJ Nutrition+1 Sleep and cognition / brain health — Nature/Harvard coverage & meta-analyses: short sleep impairs cognition and links to amyloid processes. Nature+1 Resistance training & mortality / physical function — systematic and cohort evidence that muscle-strengthening activity lowers risk and preserves function. British Journal of Sports Medicine+1 Mindfulness & mental health meta-analysis — Goyal et al. 2014 and subsequent meta-analyses showing reductions in anxiety/stress. PubMed+1 Sauna bathing and cardiovascular outcomes — JAMA Internal Medicine / Mayo Clinic Proceedings reviews on sauna and lower CVD risk signals.
Christmas is a time of celebration, when friends and family gather to enjoy meals together. However, many of us overindulge, which leaves us feeling tired, bloated, and guilty. What actually happens to our bodies when we overeat, drink more, and swap fibre for sugar? And is there a way to enjoy the season's pleasures without starting January full of regret? In this episode, ZOE's Head Nutritionist, Dr Federica Amati, joins Jonathan to explore how festive food traditions shape our health and how to navigate them without guilt or restriction. Dr Federica shares practical suggestions for gut-friendly food swaps, festive traditions worth reviving, and the one ingredient she always includes on her own Christmas table. This episode is full of helpful advice on how to care for your body in a season that often asks us to do the opposite. Unwrap the truth about your food
Send us a Text Message (please include your email so we can respond!)Episode 79! We talk all about perfusion with arterial lines in EVERDAC and personalized resuscitation with ANDROMEDA SHOCK 2! EVERDAC: https://pubmed.ncbi.nlm.nih.gov/41159885/EVERDAC (NEJM): https://www.nejm.org/doi/10.1056/NEJMoa2502136ANDROMEDA SHOCK 2: https://pubmed.ncbi.nlm.nih.gov/41159835/ANDROMEDA SHOCK 2(JAMA): https://jamanetwork.com/journals/jama/fullarticle/2840823If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
Brooklyn/ Botswana/Ariège x Paris/Londres/Kingston, à vos marques ! Notre 1ère invitée est l'artiste américaine Natalia M. King pour la sortie de son 8ème album Afroblues. Natalia M. King est une chanteuse, compositrice et guitariste américaine qui fusionne blues, jazz, soul et folk. Voix puissante du blues et du jazz modernes, elle captive par ses interprétations émouvantes. En 2025, elle franchit une nouvelle étape avec AfroBlues, un album mêlant pop dansante, afrobeat et sonorités blues. Son premier extrait, «Dumela», rend hommage à son voyage au Botswana, à sa terre rouge et à son peuple, capturant la beauté et la sagesse de ce lieu à travers sa musique. AfroBlues sera une fusion audacieuse des genres, réunissant les rythmes contagieux de l'afrobeat, des éléments de danse électronique et le soupçon de blues qui a défini sa carrière. Ce virage musical représente l'évolution continue de Natalia M. King en tant qu'artiste ne craignant pas d'expérimenter de nouveaux sons et styles. L'album est une exploration du rythme, de l'énergie et de la fusion culturelle, autour des thèmes de l'autonomisation, de la joie et de la résilience qui sont au cœur de l'album. Grâce à sa capacité à mélanger divers éléments musicaux, AfroBlues promet d'être un ajout unique et passionnant à sa discographie. À propos du premier single «Dumela» : Il existe un petit «Royaume-Uni» qui borde l'Afrique du Sud de Nelson Mandela. Une merveilleuse opportunité, par le biais de l'amour, m'y a transportée au printemps 2024 dans le merveilleux pays africain du Botswana. Les paysages, les odeurs et les sons m'ont rappelé des souvenirs oubliés. «Dumela», qui signifie bonjour en setswana (ou tswana), est mon hommage à cette mémoire oubliée et aux belles âmes que j'ai rencontrées là-bas. Je remercie les pluies et la terre rouge qui m'ont inspirée... Dumela Botswana ! Dumela Afrique ! Merci pour votre sagesse et nous nous reverrons. Natalia M. King Titres interprétés au grand studio - Dumela Live RFI - Lost & Everywhere, extrait de l'album - I Love A Woman Live RFI. Line Up : Natalia M. King (voix, guitare), Vince Laurent (batterie) & Damien Argentieri (claviers & moog). Son : Mathias Taylor & Jérémie Besset ► Album AfroBlues (Natalia M. King / Modulor 2025). Instagram - Facebook - YouTube. Puis nous recevons l'artiste britannique ALA.NI pour la sortie de Sunshine Music Lorsque ALA.NI a commencé à écrire Sunshine Music, son troisième album, l'hiver parisien de 2023 battait son plein, avec un froid mordant. Composant sous des couches de couettes dans son appartement de l'Opéra, elle puisait sa chaleur non pas dans son environnement, mais dans les souvenirs du soleil des Caraïbes qu'elle venait de quitter. Ce qui devait être un voyage de deux semaines en décembre 2020 s'est transformé en deux ans et demi entre la Barbade, la Grenade — où ses parents avaient grandi — puis la Jamaïque, un long séjour qui lui a offert un nouveau sentiment d'identité. «Vivre en Jamaïque, c'était la première fois que j'habitais dans un pays à majorité noire», dit-elle. «Les Jamaïcains sont très eux-mêmes, sans s'excuser. J'ai choisi de vivre à Paris, et je me sens plus moi-même, plus expressive et plus à l'aise ici qu'à Londres, et davantage appréciée et reconnue en tant qu'artiste aussi. Mais il y a des microagressions et des microracismes auxquels nous devons faire face chaque jour en tant que personnes de couleur. Quand je suis sortie de cet environnement, je me suis dit : «Merde, c'est ça que je gérais tout ce temps.» J'avançais simplement en acceptant certains comportements négatifs comme un acte de survie mentale.» En Jamaïque, elle a collaboré avec Sly Dunbar, l'un des batteurs légendaires de l'île, le sortant presque de sa retraite pour une session improvisée. Sunshine Music vibre du souvenir de cette chaleur : une tapisserie d'influences mêlant calypso, jazz, bossa nova et le grand répertoire d'après-guerre, le tout tissé par la voix et la sensibilité singulières d'ALA.NI. Tout au long de l'album, des styles familiers sont honorés sans pastiche : la langueur du reggae, le souffle d'un rythme bossa nova, la diction nette du théâtre musical. Titres interprétés au grand studio - Seaweed Live RFI - Tief, extrait de l'album - This is Why Live RFI. RFI Vidéos YT Line Up : Alani (chant), Thomas Naïm (guitare) Son : Mathias Taylor, Benoît Letirant ► Album Sunshine Music (No Format 2025). Instagram - Bandcamp - YT Concert 9 février 2026, Théâtre Athénée Louis Jouvet, Paris.
In the last ten years, 'diagnostic stewardship' has emerged as a core principle of good clinical practice whose implementation impacts both the individual patient and public health at large. In this episode of Communicable, hosts Angela Huttner and Annie Joseph invite two experts in the field, Daniel Morgan (Maryland, USA) and Valerie Vaughn (Utah, USA), to discuss diagnostic stewardship in the context of infectious diseases, hospital medicine, and healthcare in general. Other topics covered include practical interventions for better testing practices and the role of artificial intelligence in the future of diagnostics. The episode highlights how thoughtful, intentional diagnostic practices can enhance clinician workflows and improve patient outcomes.This episode is a follow-up from Morgan's recently published commentary in CMI Communications on diagnostic testing, and the need for evaluating its clinical impact [1]. The episode was peer reviewed by Özlem Türkmen Recen of Çınarcık State Hospital, Yalova, Türkiye. ReferencesBaghdadi JD & Morgan DJ. Diagnostic tests should be assessed for clinical impact. CMI Comms 2024. DOI: 10.1016/j.cmicom.2024.105010Further readingAdvani S and Vaughn VM. Quality Improvement Interventions and Implementation Strategies for Urine Culture Stewardship in the Acute Care Setting: Advances and Challenges. Curr Infect Dis Rep 2021. DOI: 10.1007/s11908-021-00760-3 Core Elements of Hospital Antibiotic Stewardship Programs, https://www.cdc.gov/antibiotic-use/hcp/core-elements/hospital.html Core Elements of Hospital Diagnostic Excellence (DxEx), https://www.cdc.gov/patient-safety/hcp/hospital-dx-excellence/index.htmlCosgrove SE & Srinivasan A. Antibiotic Stewardship: A Decade of Progress. Infect Dis Clin North Am 2023. DOI: 10.1016/j.idc.2023.06.003 Dik JH, et al. Integrated Stewardship Model Comprising Antimicrobial, Infection Prevention, and Diagnostic Stewardship (AID Stewardship). J Clin Microbiol 2017. DOI: 10.1128/jcm.01283-17Fabre V, et al. Principles of diagnostic stewardship: A practical guide from the Society for Healthcare Epidemiology of America Diagnostic Stewardship Task Force. Infect Control Hosp Epidemiol 2023. DOI: 10.1017/ice.2023.5 Huttner A, et al. Re: ‘ESR and CRP: it's time to stop the zombie tests' by Spellberg et al. CMI 2025. DOI: 10.1016/j.cmi.2024.09.016 Morgan DJ, et al. Diagnostic Stewardship—Leveraging the Laboratory to Improve Antimicrobial Use. JAMA 2017. DOI: 10.1001/jama.2017.8531 Messacar K, et al. Implementation of rapid molecular infectious disease diagnostics: the role of diagnostic and antimicrobial stewardship. J Clin Microbiol 2017. DOI: 10.1128/jcm.02264-16Messacar K, et al. Clinical and Financial Impact of a Diagnostic Stewardship Program for Children with Suspected Central Nervous System Infection. J Pediatr. 2022. DOI: 10.1016/j.jpeds.2022.02.002 Qian ET, et al. Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized With Acute Infection: The ACORN Randomized Clinical Trial. JAMA 2023. DOI: 10.1001/jama.2023.20583 Siontis KC et al. Diagnostic tests often fail to lead to changes in patient outcomes. J Clin Epidemiol 2014. DOI: 10.1016/j.jclinepi.2013.12.008Vaughn VM, et al. Antibiotic Stewardship Strategies and Their Association With Antibiotic Overuse After Hospital Discharge. Clin Infect Dis 2022. DOI: 10.1093/cid/ciac104Vaughn VM, et al. A Statewide Quality Initiative to Reduce Unnecessary Antibiotic Treatment of Asymptomatic Bacteriuria. JAMA Intern Med 2023. DOI: 10.1001/jamainternmed.2023.2749
Brooklyn/ Botswana/Ariège x Paris/Londres/Kingston, à vos marques ! Notre 1ère invitée est l'artiste américaine Natalia M. King pour la sortie de son 8ème album Afroblues. Natalia M. King est une chanteuse, compositrice et guitariste américaine qui fusionne blues, jazz, soul et folk. Voix puissante du blues et du jazz modernes, elle captive par ses interprétations émouvantes. En 2025, elle franchit une nouvelle étape avec AfroBlues, un album mêlant pop dansante, afrobeat et sonorités blues. Son premier extrait, «Dumela», rend hommage à son voyage au Botswana, à sa terre rouge et à son peuple, capturant la beauté et la sagesse de ce lieu à travers sa musique. AfroBlues sera une fusion audacieuse des genres, réunissant les rythmes contagieux de l'afrobeat, des éléments de danse électronique et le soupçon de blues qui a défini sa carrière. Ce virage musical représente l'évolution continue de Natalia M. King en tant qu'artiste ne craignant pas d'expérimenter de nouveaux sons et styles. L'album est une exploration du rythme, de l'énergie et de la fusion culturelle, autour des thèmes de l'autonomisation, de la joie et de la résilience qui sont au cœur de l'album. Grâce à sa capacité à mélanger divers éléments musicaux, AfroBlues promet d'être un ajout unique et passionnant à sa discographie. À propos du premier single «Dumela» : Il existe un petit «Royaume-Uni» qui borde l'Afrique du Sud de Nelson Mandela. Une merveilleuse opportunité, par le biais de l'amour, m'y a transportée au printemps 2024 dans le merveilleux pays africain du Botswana. Les paysages, les odeurs et les sons m'ont rappelé des souvenirs oubliés. «Dumela», qui signifie bonjour en setswana (ou tswana), est mon hommage à cette mémoire oubliée et aux belles âmes que j'ai rencontrées là-bas. Je remercie les pluies et la terre rouge qui m'ont inspirée... Dumela Botswana ! Dumela Afrique ! Merci pour votre sagesse et nous nous reverrons. Natalia M. King Titres interprétés au grand studio - Dumela Live RFI - Lost & Everywhere, extrait de l'album - I Love A Woman Live RFI. Line Up : Natalia M. King (voix, guitare), Vince Laurent (batterie) & Damien Argentieri (claviers & moog). Son : Mathias Taylor & Jérémie Besset ► Album AfroBlues (Natalia M. King / Modulor 2025). Instagram - Facebook - YouTube. Puis nous recevons l'artiste britannique ALA.NI pour la sortie de Sunshine Music Lorsque ALA.NI a commencé à écrire Sunshine Music, son troisième album, l'hiver parisien de 2023 battait son plein, avec un froid mordant. Composant sous des couches de couettes dans son appartement de l'Opéra, elle puisait sa chaleur non pas dans son environnement, mais dans les souvenirs du soleil des Caraïbes qu'elle venait de quitter. Ce qui devait être un voyage de deux semaines en décembre 2020 s'est transformé en deux ans et demi entre la Barbade, la Grenade — où ses parents avaient grandi — puis la Jamaïque, un long séjour qui lui a offert un nouveau sentiment d'identité. «Vivre en Jamaïque, c'était la première fois que j'habitais dans un pays à majorité noire», dit-elle. «Les Jamaïcains sont très eux-mêmes, sans s'excuser. J'ai choisi de vivre à Paris, et je me sens plus moi-même, plus expressive et plus à l'aise ici qu'à Londres, et davantage appréciée et reconnue en tant qu'artiste aussi. Mais il y a des microagressions et des microracismes auxquels nous devons faire face chaque jour en tant que personnes de couleur. Quand je suis sortie de cet environnement, je me suis dit : «Merde, c'est ça que je gérais tout ce temps.» J'avançais simplement en acceptant certains comportements négatifs comme un acte de survie mentale.» En Jamaïque, elle a collaboré avec Sly Dunbar, l'un des batteurs légendaires de l'île, le sortant presque de sa retraite pour une session improvisée. Sunshine Music vibre du souvenir de cette chaleur : une tapisserie d'influences mêlant calypso, jazz, bossa nova et le grand répertoire d'après-guerre, le tout tissé par la voix et la sensibilité singulières d'ALA.NI. Tout au long de l'album, des styles familiers sont honorés sans pastiche : la langueur du reggae, le souffle d'un rythme bossa nova, la diction nette du théâtre musical. Titres interprétés au grand studio - Seaweed Live RFI - Tief, extrait de l'album - This is Why Live RFI. RFI Vidéos YT Line Up : Alani (chant), Thomas Naïm (guitare) Son : Mathias Taylor, Benoît Letirant ► Album Sunshine Music (No Format 2025). Instagram - Bandcamp - YT Concert 9 février 2026, Théâtre Athénée Louis Jouvet, Paris.
Cette semaine, focus sur une véritable légende de la musique : Jimmy Cliff. Premier artiste à faire rayonner le reggae bien au-delà des frontières de la Jamaïque, chanteur et compositeur, il a marqué l'histoire de ce genre engagé. De ses débuts marqués par la pauvreté à ses plus grands succès internationaux, il a consacré plus de 50 ans à une musique porteuse de sens. Décédé à l'âge de 81 ans ce lundi 24 novembre, il laisse derrière lui l'héritage d'un artiste qui voyait sa musique comme un moyen de rendre le monde meilleur.
The latest JAMA article on keratinocyte carcinomas
Dans La note secrète du 29 novembre, hommage à Jimmy Cliff, légende du reggae jamaïcain, décédé à 81 ans à Kingston des suites d'une pneumonie. Né James Chambers en 1944, il a marqué l'histoire avec des titres mythiques comme Many Rivers to Cross et vendu plus de 25 millions d'albums. Acteur également, il a joué dans le film culte Tout, tout de suite en 1972. Ses obsèques auront lieu prochainement en Jamaïque.À retenir :Décès de Jimmy Cliff, icône mondiale du reggae.Carrière internationale : plus de 25 millions d'albums vendus.Acteur dans le film Tout, tout de suite (1972).Notre équipe a utilisé un outil d'Intelligence artificielle via les technologies d'Audiomeans© pour accompagner la création de ce contenu écrit.Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.
Cette semaine, focus sur une véritable légende de la musique : Jimmy Cliff. Premier artiste à faire rayonner le reggae bien au-delà des frontières de la Jamaïque, chanteur et compositeur, il a marqué l'histoire de ce genre engagé. De ses débuts marqués par la pauvreté à ses plus grands succès internationaux, il a consacré plus de 50 ans à une musique porteuse de sens. Décédé à l'âge de 81 ans ce lundi 24 novembre, il laisse derrière lui l'héritage d'un artiste qui voyait sa musique comme un moyen de rendre le monde meilleur.
A couple of weeks ago, the FDA Commissioner published a WSJ oped “The FDA Liberates Women's Hormone Replacement Therapy” (←gift link) and, with other FDA colleagues, a JAMA essay entitled “Updated Labeling for Menopausal Hormone Therapy” (open-access). That change, and the data cited, led to a series of articles in the days that followed, such as at STAT News “FDA reverses decades-old warning on hormone therapy products for menopause. Agency says the treatments o!fer heart, brain, and bone health benefits” and at the Washington Post “The FDA finally corrects its error on menopause hormone therapy. Women have been needlessly scared away from effective treatments.” If you read through these links, you'll be confused. Does MHT have proven cognitive benefits? What about a study from 1991 that showed ~50% reduction of fatal heart events with MHT? Or the 35% decreased risk of Alzheimer's disease? Or the breast cancer increased risk attributed to medroxyprogesterone acetate?I turned to my go-to gynecologist truth teller, Dr. Jen Gunter, to get her review of the evidence. This is a complex topic, with old data from the 2002 Women's Heath Initiative (WHI), new reports since, population level analysis, changes in preparations of MHT including local delivery, and much more.Here is our conversation which isn't just about MHT but includes “Big Wellness” marketing direct to middle aged women, the new FDA approved drug for hot flashes, the $14 million cut of the NIH's Office of Women's Health , marked increase in philanthropic support of women's health research, the Surgeon General nominee, ovarian failure, and a lightning round on proven benefits of MHT.Here's a brief clip on her views of the women's health “wellness” predatorsWe also discussed the reasons for Dr. Gunter's planned move next year back to Canada after practicing gynecology for 3 decades in the United States. I referred to a recent GT I wrote about the WHI and the potential favorable impact of MHT on the immune system, as suggested by new data on organ clocks. That finding, which has been replicated, may be linked to healthy aging, extending healthspan.****************************Thanks to the >190,000 Ground Truths subscribers from every US state and 210 countries. Your subscription to these free essays and podcasts makes my work in putting them together worthwhile.If you found this interesting PLEASE share it!Paid subscriptions are voluntary and all proceeds from them go to support Scripps Research. They do allow for posting comments and questions, which I do my best to respond to. Please don't hesitate to post comments and give me feedback. Let me know topics that you would like to see covered.Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. It enabled us to accept and support 47 summer interns in 2025! We aim to accept even more of the several thousand who will apply for summer 2026.Thank you Debbie Weil, Cynthia Brumfield, Sara Garcia, Harshi Peiris, Ph.D., Liane Moccia, and over 1,000 others for tuning into my live video with Dr. Jen Gunter! Join me for my next live video in the app. Get full access to Ground Truths at erictopol.substack.com/subscribe
durée : 00:05:57 - Dans la playlist de France Inter - Dans son cinquième album, la chanteuse hyper-star multiplie les cadences et les langues. Parmi les duos remarquables, celui de la reine du dancehall Jamaïcain Shenseea. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.
durée : 00:56:11 - Very Good Trip - par : Michka Assayas - Ce soir, une seule voix, celle d'un précurseur qui vient de nous quitter. Et grâce auquel une île, la Jamaïque, qui n'avait jusque-là rien apporté à la musique à l'échelle du monde, s'est mise à exister. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.
From 18th century London to the promise of a global cure: the 200-year history of Parkinson's disease. To mark the release of our 'Ask the MD' conversation with The Michael J. Fox Foundation for Parkinson's Research, and to welcome a new influx of listeners, we're sharing one of our very first episodes, first aired in August 2024. Watch our full 'Ask the MD' interview, focused on lifestyle strategies for boosting brain health, on the foundation's website: https://www.michaeljfox.org/news/lifestyle-strategies-boost-brain-health-ask-md-video Parkinson's, a neurodegenerative disorder most commonly characterized by tremors and other motor symptoms, is so complex, many medical professionals are starting to classify it as a group of diseases, rather than a single disease. In this episode, we explain those complexities, including: • The motor symptoms (e.g. cogwheel rigidity, bradykinesia) and non-motor symptoms (e.g. depression, sleep disorders) • How the industrial revolution may have brought about environmental factors which contribute to Parkinson's • The differences and similarities between Parkinson's and other neurodegenerative diseases, like Alzheimer's • How Parkinson's manifests in our brains • Why one nurse was able to detect Parkinson's through smell • The neurogenetics of Parkinson's, and the ethical quandaries of evolving genetic technology • Why lifestyle — nutrition, exercise, etc. — is so key to preventing and managing Parkinson's Joining us for this extensive conversation are three incredible guests: • Dr. Rachel Dolhun, Senior Vice President of Medical Communications at The Michael J. Fox Foundation for Parkinson's Research • Dr. Michael Okun, evolutionary biologist, movement disorders specialist, and Director of the Norman Fixel Institute for Neurological Diseases • Dr. Matthew Farrer, neurogenetics expert and Professor Of Neurology at the University of Florida 'Your Brain On' is hosted by neurologists, scientists, and public health advocates Ayesha and Dean Sherzai. SUPPORTED BY: the 2026 NEURO World Retreat. A 5-day journey through science, nature, and community, on the California coastline: https://www.neuroworldretreat.com/ 'Your Brain On... Parkinson's' • SEASON 6 • EPISODE 4 (SEASON 3 REUPLOAD) ————— LINKS Dr. Rachel Dolhun: At the Michael J. Fox Foundation: https://www.michaeljfox.org/bio/rachel-dolhun-md-dipablm 'Ask the MD' series: https://www.michaeljfox.org/ask-md The Michael J. Fox Foundation on YouTube: https://www.youtube.com/@michaeljfoxfoundation/videos Dr. Michael Okun: At the University of Florida: https://neurology.ufl.edu/profile/okun-michael/ The book 'Ending Parkinson's Disease': https://endingpd.org/ The Norman Fixel Institute: https://fixel.ufhealth.org/ Dr. Matthew Farrer: At the University of Florida: https://neurology.ufl.edu/profile/farrer-matthew/ ————— References: Bloem, B. R., Okun, M. S., & Klein, C. (2021). Parkinson's disease. The Lancet, 397(10291), 2284-2303. Morris, H. R., Spillantini, M. G., Sue, C. M., & Williams-Gray, C. H. (2024). The pathogenesis of Parkinson's disease. The Lancet, 403(10423), 293-304. Dorsey, E., Sherer, T., Okun, M. S., & Bloem, B. R. (2018). The emerging evidence of the Parkinson pandemic. Journal of Parkinson's disease, 8(s1), S3-S8. Dorsey, E. R., Okun, M. S., & Tanner, C. M. (2021). Bad Air and Parkinson Disease—The Fog May Be Lifting. JAMA neurology, 78(7), 793-795. Tsalenchuk, M., Gentleman, S. M., & Marzi, S. J. (2023). Linking environmental risk factors with epigenetic mechanisms in Parkinson's disease. npj Parkinson's Disease, 9(1), 123. Reynoso, A., Torricelli, R., Jacobs, B. M., Shi, J., Aslibekyan, S., Norcliffe‐Kaufmann, L., ... & Heilbron, K. (2024). Gene–Environment Interactions for Parkinson's Disease. Annals of Neurology, 95(4), 677-687. Golsorkhi, M., Sherzai, A., & Dashtipour, K. The Influence of Lifestyle on Parkinson's Disease Management. In Lifestyle Medicine, Fourth Edition (pp. 919-924). CRC Press. Sherzai, A. Z., Tagliati, M., Park, K., Pezeshkian, S., & Sherzai, D. (2016). Micronutrients and risk of Parkinson's disease: a systematic review. Gerontology and geriatric medicine, 2, 2333721416644286. ————— FOLLOW US Join NEURO Instagram: @thebraindocs Website: TheBrainDocs.com More info and episodes: TheBrainDocs.com/Podcast
What does a goiter and syphilis have in common with the first descriptions of giant cell arteritis? Join us as we dive into the history of the most common type of vasculitis! Intro 0:13 GCA at ACR 2025 00:30 How Brown has approached framing this episode 1:01 A primer leading us to GCA 3:15 Let's get to the story 4:02 The man who couldn't wear a hat 4:57 Dr. Bayard Horton's 7:40 A tangent on cluster headaches 8:27 Let's get back to GCA 13:16 The first temporal artery biopsy 14:28 Vision loss and other puzzle pieces of GCA 16:27 What about jaw claudication? 21:15 Could GCA be transmissible? Injecting ground temporal arteries into healthy volunteers 24:13 Oxygen? Histamines? Adrenal cortical extract? Looking for GCA treatments 26:55 Steroids and GCA 28:40 A quote from the 1959 Mayo Clinic Board of Governors 32:24 Extracranial involvement in GCA 33:24 When did we recognize aorta involvement? Syphilis enters the picture 35:08 A recap of the history of GCA 41:25 Thanks for listening 42:19 We'd love to hear from you! Send your comments/questions to Dr. Brown at rheuminationspodcast@healio.com. Follow us on Twitter @HRheuminations @AdamJBrownMD @HealioRheum. References: Boes CJ, Cephalalgia. 2007;doi:10.1111/j.1468-2982.2007.01238.x Cummer CL, et al. JAMA. 1912;doi:10.1001/jama.1912.04270080101004 Horton BT, Proc Cent SOC Clin Res. 1946 Sproul EE, et al. Am J Pathol. 1937;PMID: 19970328 Disclosures: Brown reports no relevant financial disclosures.
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Jamil Abdullah Al-Amin, formerly known as civil rights leader H. Rap Brown, is an American Muslim cleric and former Black Power activist whose life has spanned community organizing, political leadership, and later religious guidance. He died this week at the age of 82 in a correctional medical facility. We'll talk with Kalonji Changa and Dhoruba Bin Wahad about his legacy. Kalonji Jama Changa is an organizer, founder of the FTP Movement, and the co-chair of the Urban Survival and Preparedness Institute and is co-founder of Black Power Media. He is also author of the bestselling book, “How to Build a People's Army” and co-producer of the documentary “Organizing is the New Cool.” Dhoruba bin Wahad is an American political activist and author, former leader of the New York Black Panther Party, and co-founder of the Black Liberation Army. He was one of the Panther 21 defendants charged in 1969 with conspiracy to attack New York City police stations. — Subscribe to this podcast: https://plinkhq.com/i/1637968343?to=page Get in touch: lawanddisorder@kpfa.org Follow us on socials @LawAndDis: https://twitter.com/LawAndDis; https://www.instagram.com/lawanddis/ The post Remembering Jamil Abdullah Al-Amin w/ Dhoruba Bin Wahad and Kalonji Jama Changa appeared first on KPFA.
L'émission 28 minutes du 25/11/2025 50 ans de la mort de Franco : un roman entre exil familial et fantômes du franquisme50 ans après la mort du dictateur Franco, l'Espagne est toujours aussi divisée sur l'héritage laissé par le Caudillo. Léonor de Récondo, écrivaine et violoniste réputée, est née dans une famille espagnole exilée, fuyant la guerre d'Espagne en 1936. Ses racines, ainsi que la quête de la nationalité espagnole sont au cœur de son dernier roman : "Marcher dans tes pas" (éditions de l'Iconoclaste). Dans ce roman hybride, se mêlent souvenirs, imagination et poésie. Elle est notre invitée ce soir.Féminicides en hausse : à quand un électrochoc en France ?En 2024 en France, chaque jour, plus de trois femmes étaient victimes de féminicide ou de tentative de féminicide selon les données de la Mission ministérielle pour la protection des femmes (Miprof). Dans la même année, 107 femmes ont été tuées sous les coups de leur conjoint ou ex-conjoint, contre 96 en 2023. Cette hausse cache une faille collective, un manque de formation des policiers et des magistrats. Les violences faites aux femmes étaient pourtant la "grande cause nationale" d'Emmanuel Macron au début de ces deux mandats. Ce mardi 25 novembre, en cette journée nationale de lutte contre les violences faites aux femmes, deux magistrats ont remis un rapport à Gérald Darmanin, contenant dix propositions. Ils préconisent notamment la mise en place d'un “juge des VIF”, les violences intrafamiliales.On en débat avec Mine Günbay, directrice générale de la Fédération nationale Solidarité Femmes, Céline Marcovici, avocate au Barreau de Paris et Éric Corbaux, procureur général près la cour d'appel de Bordeaux.Enfin, Xavier Mauduit revient aux origines du reggae apparu en Jamaïque dans les années 1950, alors que son précurseur, Jimmy Cliff, est mort à l'âge de 81 ans. Marie Bonnisseau nous emmène dans des soirées techno traversées de flûtes et de cornemuses celtiques, qui cartonnent.28 minutes est le magazine d'actualité d'ARTE, présenté par Élisabeth Quin du lundi au jeudi à 20h05. Renaud Dély est aux commandes de l'émission le vendredi et le samedi. Ce podcast est coproduit par KM et ARTE Radio. Enregistrement 25 novembre 2025 Présentation Élisabeth Quin Production KM, ARTE Radio
Die Themen in den Wissensnachrichten: +++ Knochen belegen frühe Koexistenz von Mensch und Wolf +++ Social Media-Detox hilft schnell +++ Neue Korallenart wächst auf Manganknollen +++**********Weiterführende Quellen zu dieser Folge:Gray wolves in an anthropogenic context on a small island in prehistoric Scandinavia, PNAS, 24.11. 2025Social Media Detox and Youth Mental Health, JAMA, 24.11. 2025Hidden gems of the abyss: first species of azooxanthellate scleractinian coral (Scleractinia: Deltocyathidae) attached to polymetallic nodules in the eastern Pacific Ocean, Zoological Journal of the Linnean Society, November 2025The Moon-forming impactor Theia originated from the inner Solar System, Science, 20.11. 2025Shared and language-specific phonological processing in the human temporal lobe. Nature, 19.11.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok und Instagram .
Send us a message with this link, we would love to hear from you. Standard message rates may apply.Clear guidance on benefits, risks, and how the FDA's label changes shift conversations in the exam room about HRTNikki's Corner• Philly's first Michelin stars and what the tiers mean• Flying taxis in Dubai • A cold case solved by college criminology studentsLearning • What HRT is, routes of therapy, and who benefits• Reframing WHI-era fears with age and timing data• FDA label changes and clinical implications• Contraindications and safer use considerations• Women's health bias and the cost of not listening• Practical steps for shared decisions with cliniciansReferencesThe 2022 Hormone Therapy Position Statement of the North American Menopause Society. Menopause (New York, N.Y.). 2022;29(7):767-794. doi:10.1097/GME.0000000000002028.Management of Menopausal Symptoms: A Review. Crandall CJ, Mehta JM, Manson JE. JAMA. 2023;329(5):405-420. doi:10.1001/jama.2022.24140.Hormone Therapy for Postmenopausal Women. Pinkerton JV. The New England Journal of Medicine. 2020;382(5):446-455. doi:10.1056/NEJMcp1714787.Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Women: US Preventive Services Task Force Recommendation Statement. Grossman DC, Curry SJ, Owens DK, et al. JAMA. 2017;318(22):2224-2233. doi:10.1001/jama.2017.18261.Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. Gartlehner G, Patel SV, Reddy S, et al. JAMA. 2022;328(17):1747-1765. doi:10.1001/jama.2022.18324.Hormone Therapy in the Postmenopausal Years: Considering Benefits and Risks in Clinical Practice. Genazzani AR, Monteleone P, Giannini A, Simoncini T. Human Reproduction Update. 2021;27(6):1115-1150. doi:10.1093/humupd/dmab026.Hormone Therapy in Menopause: Concepts, Controversies, and Approach to Treatment. Flores VA, Pal L, Manson JE. Endocrine Reviews. 2021;42(6):720-752. doi:10.1210/endrev/bnab011.The Women's Health Initiative Randomized Trials and Clinical Practice: A Review. Manson JE, Crandall CJ, Rossouw JE, et al. JAMA. 2024;331(20):1748-1760. doi:10.1001/jama.2024.6542.Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons: US Preventive Services Task Force Recommendation Statement. Mangione CM, Barry MJ, NicSupport the showSubscribe to Our Newsletter! Production and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski
Editor's Summary by Linda Brubaker, MD, and Preeti Malani, MD, MSJ, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from November 15-21 2025.
Agaasimaha iskaashiga caalamiga ee hay'adda Rotary Club Footscray, Jama Farah, ayaa ka warramay container laga buuxiyey agabka caafimaadka oo ay Rotary Club Footscray ugu deeqday cisbitaalka Dilchora ee magaalada Dire Dawa - Ethiopia.
Major medical societies broadly support the FDA's removal of most boxed warnings from menopausal hormone therapy, emphasizing improved access and the importance of individualized risk assessment. The Americas have lost their measles-free status due to persistent outbreaks driven by low vaccination coverage, prompting PAHO to call for renewed immunization efforts and stronger surveillance. A randomized trial in JAMA found that moderate caffeinated coffee intake may reduce recurrence of atrial fibrillation after cardioversion compared with abstinence.
Radio foot internationale le jeudi 20 novembre 2025 (16h10 TU & 21h10 TU). Au programme : une finale africaine, un tirage explosif, un bilan européen et une nuit de sacres. ; CAF Awards 2025 : Hakimi au sommet, Mayele honoré ; - Mondial 2026 – Barrages Europe & Afrique : les affiches tombent ; - Éliminatoires Europe – Les favoris au rendez-vous ? ; - Finale CAF Ligue des champions féminine : AS FAR – ASEC Mimosas. CAF Awards 2025 : Hakimi au sommet, Mayele honoré Achraf Hakimi (PSG / Maroc) sacré Joueur africain de l'année. Et Fiston Mayele (RDC) récompensé comme Meilleur joueur africain évoluant en Afrique : un signe fort pour le football congolais. Mondial 2026 – Barrages Europe & Afrique : les affiches tombent Tirage tendu : Italie – Irlande du Nord, Turquie – Roumanie, Danemark – Macédoine du Nord, Pays de Galles – Bosnie… Et côté africain, la RDC est fixée : les Léopards joueront leur billet pour le Mondial face au vainqueur de Jamaïque – Nouvelle-Calédonie. Une finale de barrage intercontinental à très haute pression pour rêver de l'Amérique du Nord. Éliminatoires Europe – Les favoris au rendez-vous ? France, Espagne, Allemagne, Portugal, Belgique : les grandes nations ont fait le boulot. D'autres devront encore passer par un barrage piégeux. Le point complet sur une campagne parfois limpide, parfois inquiétante. Finale CAF Ligue des champions féminine : AS FAR – ASEC Mimosas Vendredi en Égypte, les Marocaines de l'AS FAR retrouvent une finale qu'elles connaissent par cœur, face à l'ASEC Mimosas, la sensation ivoirienne de cette édition. Duel d'expérience, talent, et confirmation de l'essor du football féminin sur le continent. Autour d'Annie Gasnier : Hervé Penot, Ludovic Duchesne et Manuel Terradillos. Édition : David Fintzel — Technique/Réalisation : Laurent Salerno.
Radio foot internationale le jeudi 20 novembre 2025 (16h10 TU & 21h10 TU). Au programme : une finale africaine, un tirage explosif, un bilan européen et une nuit de sacres. ; CAF Awards 2025 : Hakimi au sommet, Mayele honoré ; - Mondial 2026 – Barrages Europe & Afrique : les affiches tombent ; - Éliminatoires Europe – Les favoris au rendez-vous ? ; - Finale CAF Ligue des champions féminine : AS FAR – ASEC Mimosas. CAF Awards 2025 : Hakimi au sommet, Mayele honoré Achraf Hakimi (PSG / Maroc) sacré Joueur africain de l'année. Et Fiston Mayele (RDC) récompensé comme Meilleur joueur africain évoluant en Afrique : un signe fort pour le football congolais. Mondial 2026 – Barrages Europe & Afrique : les affiches tombent Tirage tendu : Italie – Irlande du Nord, Turquie – Roumanie, Danemark – Macédoine du Nord, Pays de Galles – Bosnie… Et côté africain, la RDC est fixée : les Léopards joueront leur billet pour le Mondial face au vainqueur de Jamaïque – Nouvelle-Calédonie. Une finale de barrage intercontinental à très haute pression pour rêver de l'Amérique du Nord. Éliminatoires Europe – Les favoris au rendez-vous ? France, Espagne, Allemagne, Portugal, Belgique : les grandes nations ont fait le boulot. D'autres devront encore passer par un barrage piégeux. Le point complet sur une campagne parfois limpide, parfois inquiétante. Finale CAF Ligue des champions féminine : AS FAR – ASEC Mimosas Vendredi en Égypte, les Marocaines de l'AS FAR retrouvent une finale qu'elles connaissent par cœur, face à l'ASEC Mimosas, la sensation ivoirienne de cette édition. Duel d'expérience, talent, et confirmation de l'essor du football féminin sur le continent. Autour d'Annie Gasnier : Hervé Penot, Ludovic Duchesne et Manuel Terradillos. Édition : David Fintzel — Technique/Réalisation : Laurent Salerno.
Home-delivered DASH-patterned groceries paired with dietitian counseling meaningfully lowered blood pressure and LDL cholesterol among Black adults living in food deserts
In this episode, Dr. Sergio Zanotti discusses the assessment of peripheral perfusion as a tool to guide treatment in septic shock. Specifically, he dives into Capillary Refill Time. He is joined by Dr. Eduardo Kattan, a critical care and anesthesia physician. Dr. Kattan is an Assistant Professor at the Pontificia Catholic University of Chile, where he also serves as Adult Critical Care Program Director and Director of Research and Academics in the Department of Critical Care Medicine. A prolific investigator, he focuses his research on septic shock and medical education. Dr. Rattan is the Co-Principal Investigator of the recently published ANDROMEDA-SHOCK 2 clinical trial. Additional resources: Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock. The ANDORMEDA-SHOCK-2 Randomized Clinical Trial. JAMA 2025: https://jamanetwork.com/journals/jama/fullarticle/2840823 Effect of Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on. 28-Day Mortality Among Patients With Septic Shock. The ANDROMEDA-SHOCK Randomized Clinical Trial. JAMA 2019: https://jamanetwork.com/journals/jama/fullarticle/2724361 Perspectives on peripheral perfusion assessment. Eduardo Kattan, et al. Curr Opin Crit Care 2023: https://pubmed.ncbi.nlm.nih.gov/37078639/ Books mentioned in this episode: The Little Prince. By Antoine de Saint-Exupery: https://bit.ly/49YcSRJ The Autumn Ghost: How the Battle Against a Polio Epidemic Revolutionized Modern Medical Care. By Hannah Wunsch: https://bit.ly/4i9PiUf
Send us a Text Message (please include your email so we can respond!)Episode 78! We start our discussion of the trials that drop with ESICM with the much anticipated BICAR-ICU 2! Then we talk briefly about some changes to the SOFA score with the new SOFA-2 score. BICAR-ICU2: https://pubmed.ncbi.nlm.nih.gov/41159812/BICAR-ICU 2 (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2840824SOFA-2: https://pubmed.ncbi.nlm.nih.gov/41159833/SOFA-2 (JAMA): https://jamanetwork.com/journals/jama/fullarticle/2840822If you enjoy the show be sure to like and subscribe, leave that 5 star review! Be sure to follow us on the social @icucast for the associated figures, comments, and other content not available in the audio format! Email us at icuedandtoddcast@gmail.com with any questions or suggestions! Thank you Mike Gannon for the intro and exit music!
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-459 Overview: Cognitive decline risk may be reduced through modifiable lifestyle factors, creating an opportunity for early intervention in primary care. Join us as we review findings from the US POINTER trial, which evaluated the impact of structured vs. self-guided lifestyle interventions on the risk of cognitive decline in older adults. Come away with tips to apply this evidence in real-world scenarios with your patients. Episode resource links: Baker LD, Espeland MA, Whitmer RA, et al. Structured vs self-guided multidomain lifestyle interventions for global cognitive function: The US POINTER randomized clinical trial. JAMA. 2025;334(8):681-691. doi:10.1001/jama.2025.12923 Livingston G, Huntley J, Liu KY, et al. Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission. Lancet. 2024;404(10421):572-628. doi:10.1016/S0140-6736(24)01296-0 Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-459 Overview: Cognitive decline risk may be reduced through modifiable lifestyle factors, creating an opportunity for early intervention in primary care. Join us as we review findings from the US POINTER trial, which evaluated the impact of structured vs. self-guided lifestyle interventions on the risk of cognitive decline in older adults. Come away with tips to apply this evidence in real-world scenarios with your patients. Episode resource links: Baker LD, Espeland MA, Whitmer RA, et al. Structured vs self-guided multidomain lifestyle interventions for global cognitive function: The US POINTER randomized clinical trial. JAMA. 2025;334(8):681-691. doi:10.1001/jama.2025.12923 Livingston G, Huntley J, Liu KY, et al. Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission. Lancet. 2024;404(10421):572-628. doi:10.1016/S0140-6736(24)01296-0 Guest: Jillian Joseph, MPAS, PA-C Music Credit: Matthew Bugos Thoughts? Suggestions? Email us at FranklySpeaking@pri-med.com
Send us a message with this link, we would love to hear from you. Standard message rates may apply.We discuss a clear, practical guide to menopause, explaining what it is, why it happens, and how to manage the most common symptoms with everyday steps and evidence-based options. We set up next week's deep dive on hormone therap. • Defining menopause and typical timing• Why estrogen declines and bodywide effects• Common symptoms across sleep, mood, and metabolism• Hot flashes and night sweats frequency and duration• Vaginal and urinary symptoms that mimic UTIs• Bone density loss and changing heart risk• Lifestyle tactics that actually help• When to ask about hormonal and non-hormonal treatments• Teaser for hormone therapy update next weekSend us an email at yourcheckuppod@gmail.comReferences1. Menopause-Biology, Consequences, Supportive Care, and Therapeutic Options. Davis SR, Pinkerton J, Santoro N, Simoncini T. Cell. 2023;186(19):4038-4058. doi:10.1016/j.cell.2023.08.016.2. The Menopause Transition: Signs, Symptoms, and Management Options. Santoro N, Roeca C, Peters BA, Neal-Perry G. The Journal of Clinical Endocrinology and Metabolism. 2021;106(1):1-15. doi:10.1210/clinem/dgaa764.3. Management of Menopausal Symptoms: A Review. Crandall CJ, Mehta JM, Manson JE. JAMA. 2023;329(5):405-420. doi:10.1001/jama.2022.24140.4. Menopause. Davis SR, Lambrinoudaki I, Lumsden M, et al. Nature Reviews. Disease Primers. 2015;1:15004. doi:10.1038/nrdp.2015.4.5. Menopause: Physiology, Definitions, and Symptoms. Gatenby C, Simpson P. Best Practice & Research. Clinical Endocrinology & Metabolism. 2024;38(1):101855. doi:10.1016/j.beem.2023.101855.6. Reproductive Aging in Biological Females: Mechanisms and Immediate Consequences. Muhammad YA. Frontiers in Endocrinology. 2025;16:1658592. doi:10.3389/fendo.2025.1658592.7. Treating Menopause - MHT and Beyond. Davis SR, Baber RJ. Nature Reviews. Endocrinology. 2022;18(8):490-502. doi:10.1038/s41574-022-00685-4.8. Management of Perimenopausal and Menopausal Symptoms. Duralde ER, Sobel TH, Manson JE. BMJ (Clinical Research Ed.). 2023;382:e072612. doi:10.1136/bmj-2022-072612.9. Hormone Therapy for Postmenopausal Women. Pinkerton JV. The New England Journal of Medicine. 2020;382(5):446-455. doi:10.1056/NEJMcp1714787.10. An Empowerment Model for Managing Menopause. Hickey M, LaCroix AZ, Doust J, et al. Lancet (London, England). 2024;403(10430):947-957. doi:10.1016/S0140-6736(23)02799-X.11. Menopause. Carter AE, Merriam S. The Medical Clinics of North America. 2023;107(2):199-212. doi:10.1016/j.mcna.2022.10.003.Support the showSubscribe to Our Newsletter! Production and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski
☕ DECAF Trial insight! A new JAMA study shows that daily caffeinated coffee may lower recurrence of atrial fibrillation compared with abstinence. Patients drinking ~1 cup/day had 47% recurrence vs 64% with abstinence (HR 0.61, p=0.01)
Date: November 12, 2025 Reference: Taccone et al. Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury The TRAIN Randomized Clinical Trial. JAMA 2024 Guest Skeptic: Dr. Alex Weiler is an Emergency Department staff physician in the Peterborough Regional Health Centre and is an associate professor with Queen’s University Department of Family Medicine. […] The post SGEM#492: Give Blood – To Anemic Patients with Acute Brain Injuries first appeared on The Skeptics Guide to Emergency Medicine.
Pour trouver le nom de son mythique espion, l'écrivain Ian Fleming s'est inspiré du nom d'un ornithologue américain. Il stockait d'ailleurs l'un de ses livres dans sa résidence secondaire de Jamaïque. Et vous connaissez tous son nom... GoldenEye. Ça c'est pour le nom de 007 mais pour le personnage, Fleming s'est aussi inspiré d'un homme, un vrai espion ! Il n'était pas Britannique mais Serbe. Et il s'appelait Dusko Popov... Dans "Ah Ouais ?", Florian Gazan répond en une minute chrono à toutes les questions essentielles, existentielles, parfois complètement absurdes, qui vous traversent la tête. Un podcast RTL Originals.Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.
It's Nurse Practitioners Week, and today, we have a special episode to highlight a historic moment in time. On November 11, the FDA changed the labeling on hormone replacement therapy. Join me for a short, focused episode where I read a recently published JAMA article detailing those changes, to keep you up to date on this significant development. IN THIS EPISODE, YOU WILL LEARN: How recent FDA updates are changing menopausal hormone therapy The history of estrogen's role in heart and bone health How past research sparked fear around hormone therapy What the new labeling means for patients and prescribers How individualized treatment is reshaping dosage and timing decisions. Updated FDA labeling now distinguishes between systemic and topical therapies Key considerations for menopause-related urinary and genital health How these updates will potentially impact women's long-term health Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com
Assalamu'alaikum warahmatullahi wabarakatuh!I hope you all are well. Welcome back to another episode on the Islamic Feelings podcast. This week's episode is a highly requested topic from you all on jealousy, how it shows up in our hearts, and how we can manage it through tazkiyah, self-awareness, and sincere connection to Allah. If you've been struggling with comparison or insecurity, this episode is for you. Al-Lalaka'i reported: Abu Darda, may Allah be pleased with him, said, “The pinnacle of faith is in four things: patience with the judgment of Allah, pleasure with the decree of Allah, sincerity and trust in Allah, and surrender to the Lord.”Source: Sharḥ Uṣūl I'tiqād Ahl al-Sunnah wal-Jamā'ah 1697
Editor's Summary by Linda Brubaker, MD, and Preeti Malani, MD, MSJ, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from November 8-14, 2025. Related Content: From AHA: Coffee Consumption and Atrial Fibrillation, DASH-Patterned Groceries and Effects on Blood Pressure, Oral PCSK9 Inhibitor Enlicitide for Heterozygous Familial Hypercholesterolemia, and more
Interview with Kristine A. Smith, MD, author of Evaluation of Practice Patterns for 6-Sinus Balloon Sinus Dilation; Jay F. Piccirillo, MD, author of Balloon Sinus Dilation Use; and Donald C. Lanza, MD, MS, author of Balloon Sinus Dilation—To Inflate or Not to Inflate. Hosted by Paul C. Bryson, MD, MBA. Related Content: Evaluation of Practice Patterns for 6-Sinus Balloon Sinus Dilation Balloon Sinus Dilation—To Inflate or Not to Inflate Balloon Sinus Dilation Use
Interview with Elizabeth J. Phillips, MD, author of Recovering From Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. Hosted by Adewole S. Adamson, MD. Related Content: Recovering From Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
About this Episode Episode 50 of “The 2 View” – BNPs, D-Dimers, and Sneakily Sick Kids Segment 1A - Needs of older nurses Clendon JA, Walker L. Nurses aged over 50 and their perceptions of flexible working: The experiences and needs of older nurses in relation to flexible working and the barriers and facilitators to implementation within workplaces. J Nurs Manag. 2016;24:336-346. doi:10.1111/jonm.12325 Segment 1B - WHO and Tropical Diseases Special Programme for Research and Training in Tropical Diseases. World Health Organization. Accessed August 19, 2025. https://tdr.who.int/about-us Segment 2A - BNP Silvers SM, Gemme SR, Hickey S, et al. Clinical Policy: Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Heart Failure Syndromes. Ann Emerg Med. 2019;49(2): 232–241. Lamberta M, Chertoff A. BNP Level in the Emergency Department: Does it Change Management? EMDocs. June 20, 2016. Accessed November 4, 2025. https://www.emdocs.net/bnp-level-in-the-emergency-department-does-it-change-management/ Maisel AS, Krishnaswamy P, Nowak RM, et al. Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure. N Engl J Med. 2002;347(3):161-167. doi: 10.1056/NEJMoa020233 Segment 2B - D-Dimer Wolf SJ, Hahn SA, Nentwich LM, et al. Clinical policy: Critical issues in the evaluation and management of adult patients presenting to the emergency department with suspected acute venous thromboembolic disease. Ann Emerg Med. 2018;71(5):e59–e109. doi:10.1016/j.annemergmed.2018.03.006 Righini M, Van Es J, Den Exter PL, et al. Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: The ADJUST-PE study. JAMA. 2014;311(11):1117–1124. doi:10.1001/jama.2014.2135 van der Hulle T, Cheung WY, Kooij S, et al. Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): A prospective, multicentre, cohort study. Lancet. 2017;390(10091):289–297. doi:10.1016/S0140-6736(17)30885-1 Kearon C, de Wit K, Parpia S, et al. Diagnosis of pulmonary embolism with D-dimer adjusted to clinical probability. N Engl J Med. 2019;381(22):2125–2134. doi:10.1056/NEJMoa1909159 Lim w, Le Gal G, Bates SM, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: Diagnosis of venous thromboembolism. Blood Adv. 2018;2(22):3226-3256. doi:10.1182/bloodadvances.2018024828 Kabrhel C, Jaff MR, Channick RN. D-dimer. StatPearls. June 22, 2025. Accessed November 4, 2025. https://www.ncbi.nlm.nih.gov/books/NBK431064/ Tripodi A, Lippi G. How we manage a high D-dimer. Haematologica. 2020;106(6):1491-1494. doi:10.3324/haematol.2020.248344 Segment 3: Sneakily Sick Kids Kocher MS, Zurakowski D, Kasser JR. Differentiating between septic arthritis and transient synovitis of the hip in children: An evidence-based clinical prediction algorithm. J Bone Joint Surg Am. 1999;81(12):1662-1670. doi:10.2106/00004623-199912000-00002 Caird MS, Flynn JM, Leung YL, et al. Factors distinguishing septic arthritis from transient synovitis of the hip in children: a prospective study. J Bone Joint Surg Am. 2006;88(6): 1251-1257. doi:10.2106/JBJS.E.00216 Recurring Sources Center for Medical Education. http://ccme.org The Proceduralist. http://www.theproceduralist.org The Procedural Pause. https://journals.lww.com/em-news/blog/theproceduralpause/pages/default.aspx The Skeptics Guide to Emergency Medicine. http://www.thesgem.com Be sure to keep tuning in for more great prizes and fun trivia questions! Once you hear the question, please email us your guesses at 2viewcast@gmail.com and tell us who you want to give a shout-out to.
Send us a message with this link, we would love to hear from you. Standard message rates may apply.We break down osteopenia and osteoporosis with clear steps to protect independence: how bones weaken, how DEXA scoring works, and which daily habits reduce fracture risk. We share nutrition, exercise, lifestyle changes, and home safety that make a measurable difference.• key stats on fracture risk in women and men over 50• definitions of osteopenia and osteoporosis using T-scores• hip, spine and wrist as common fracture sites• why bone loss accelerates after menopause• risk factors including family history, smoking and low weight• DEXA scan basics and when to ask for screening• calcium and vitamin D targets and food sources• Mediterranean diet, protein and supportive micronutrients• weight-bearing, resistance and balance training essentials• Tai Chi and fall risk reduction• home safety changes that prevent falls• when medications like bisphosphonates or denosumab help• practical questions to ask your clinicianReferences1. Osteoporosis: Common Questions and Answers. Harris K, Zagar CA, Lawrence KV. American Family Physician. 2023;107(3):238-246.2. Postmenopausal Osteoporosis. Walker MD, Shane E. The New England Journal of Medicine. 2023;389(21):1979-1991. doi:10.1056/NEJMcp2307353.3. American Association of Clinical Endocrinologists/American College of Endocrinology Clinical Practice Guidelines for the Diagnosis and Treatment of Postmenopausal Osteoporosis-2020 Update. Camacho PM, Petak SM, Binkley N, et al. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 2020;26(Suppl 1):1-46. doi:10.4158/GL-2020-0524SUPPL.4. Global, Regional Prevalence, and Risk Factors of Osteoporosis According to the World Health Organization Diagnostic Criteria: A Systematic Review and Meta-Analysis. Xiao PL, Cui AY, Hsu CJ, et al. Osteoporosis International : A Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2022;33(10):2137-2153. doi:10.1007/s00198-022-06454-3.5. Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement. Curry SJ, Krist AH, Owens DK, et al. JAMA. 2018;319(24):2521-2531. doi:10.1001/jama.2018.7498.6. The Cost of Osteoporosis, Osteopenia, and Associated Fractures in Australia in 2017. Tatangelo G, Watts J, Lim K, et al. Journal of Bone and Mineral Research : The Official Journal of the American Society for Bone and Mineral Research. 2019;34(4):616-625. doi:10.1002/jbmr.3640.7. The Prevalence and Treatment Rate Trends of Osteoporosis in Postmenopausal Women. Zhang X, Wang Z, Zhang D, et al. PloS One. 2023;18(9):e0290289. doi:10.1371/journal.pone.0290289.8. Osteopenia: A Key Target for Fracture Prevention. Reid IR, McClung MR. The Lancet. Diabetes & Endocrinology. 2024;12(11):856-864. doi:10.1016/S2213-8587(24)00225-0.9. Effectiveness and Safety of Treatments to Prevent Fractures in People With Low Bone Mass or Primary Osteoporosis: A Living Systematic Review and Network Meta-Analysis for the American College of Physicians. Ayers C, Kansagara D, Lazur B, et al. Annals of Internal Medicine. 2023;176(2):182-195. doi:10.7326/M22-0684.Support the showSubscribe to Our Newsletter! Production and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski
Recently, a new version of the Sequential Organ Failure Assessment (SOFA) score was introduced.Known as SOFA-2, this new definition aligns with organ dysfunction measurement in critically ill adults with current clinical practices, especially those diagnosed with sepsis.Published in the Journal of the American Medical Association (JAMA) on Oct. 29 and available at https://jamanetwork.com/journals/jama/fullarticle/2840822, this revised tool updates the original 1996 SOFA score, which had remained unchanged despite evolving treatment modalities and technologies. During the next live edition of Monitor Mondays, Dr. James S. Kennedy will discuss this SOFA-2 revision and its expected impact on clinical validation for sepsis – defined by Sepsis-3 as a life-threatening organ dysfunction caused by a dysregulated host response to infection – and how facility clinical workflows can negotiate denial avoidance with payers with this challenging diagnosis.The weekly broadcast will also include these instantly recognizable features:Monday Rounds: Ronald Hirsch, MD, vice president of R1 RCM, will be making his Monday Rounds.The RAC Report: Healthcare attorney Knicole Emanuel, partner at the law firm of Nelson Mullins, will report the latest news about auditors.Risky Business: Healthcare attorney David Glaser, shareholder in the law offices of Fredrikson & Byron, will join the broadcast with his trademark segment.Legislative Update: Cate Brantley, senior healthcare legislative affairs analyst for Zelis, will report on the news happening at the intersection of healthcare and congressional action.
In this episode of Hold Your Fire!, Richard is joined by Crisis Group's Cameroon expert Arrey E. Ntui and Sahel director Jean-Hervé Jézéquel. Richard first talks with Arrey about the fallout from Cameroon's disputed elections, growing public anger toward President Paul Biya – the world's oldest serving head of state – and opposition protests. They also assess how the political crisis might affect Cameroon's long-running Anglophone conflict and risks for further escalation. Richard then turns to Jean-Herve to discuss the blockade imposed by the militant group Jama'at Nusrat al-Islam wal-Muslimin (JNIM), which has cut off fuel supplies to the capital Bamako. They examine why the military has struggled to secure key supply roads, whether the blockade signals a shift in JNIM's strategy, how it might shape public sentiment toward Mali's military rulers and whether the blockade paves the way for a jihadist takeover.Click here to listen on Apple Podcasts or Spotify. For more, check out our Cameroon and Mali pages. Hosted on Acast. See acast.com/privacy for more information.
Broadcast from KSQD, Santa Cruz on 11-06-2025:>/p> Dr. Dawn interviews Cindy Jackonette and Dr. Michael Alexander about a fundraiser for pancreatic cancer awareness on November 15th at Bargetto Winery from 2-5pm, supporting the Santa Cruz Cancer Benefit Group. Dr. Alexander explains pancreatic cancer has only 10-15% five-year survival rates and is difficult to screen for. Screening involves complex endoscopy procedures examining pancreatic ducts, CT scans and biomarker scans. The disease represents 3% of cancer cases but 8% of deaths. Immune checkpoint inhibitors show limited success except in Lynch syndrome patients with DNA repair defects. The Santa Cruz Cancer Benefit Group donates annually to local cancer organizations and is all volunteer-run with minimal overhead. An emailer asks when her 56-year-old half-African American son should get colon cancer screening given his father and uncle both had the disease. Dr. Dawn explains African Americans have increased risk and recommends immediate colonoscopy despite the ideal screening window being 10 years ago. She emphasizes identifying whether he produces polyps, which would require surveillance every 3-5 years. Unlike pancreatic cancer, colon cancer is highly curable when detected early, with death rates dropping 30-40% since colonoscopies became standard in the mid-1990s. She recommends preventive measures including daily 200mg ibuprofen (if no ulcer history) and a high-fiber diet rich in colorful vegetables containing antioxidants that reduce oxidative stress and DNA damage from free radicals. An emailer from Israel asks about supporting his 38-year-old son's rectal adenocarcinoma treatment. Dr. Dawn recommends nutritional strategies including juicing 10 different fruits and vegetables daily, 20mg melatonin for synergy with chemotherapy, vitamin D supplementation, and L-glutamine as primary food for bowel healing and lymphocyte function. She suggests DHA fish oil to enhance chemotherapy effectiveness, green tea for oncogene inhibition, astragalus herb to increase phagocytic activity and natural killer cells, and rotating water-extracted mushroom formulas with beta-glucans, particularly maitake and shitake. Glutamine also protects mucous membranes from radiation burns. Dr. Dawn discusses alarming cancer rate increases among young adults in Corn Belt states including Iowa, Nebraska, Illinois, Minnesota, Indiana, and Kansas. Since 2015, these states show 5% higher cancer rates for ages 15-49 compared to national averages, with particularly elevated kidney and skin cancer rates. Young women face 66% higher skin cancer risk than peers in other states. . Governor Kim Reynolds invested $1 million for research while Bayer's attempt to shield Roundup from lawsuits failed. Dr. Dawn notes Roundup now contains diquat after removing glyphosate. It has taken decades to accumulate evidence of glyphosates harms, She warns that absence of evidence of Diquats being harmful isn't evidence of safety and that Ames testing suggests high mutation potential. An emailer shares a JAMA article on lithium for Alzheimer's disease. Dr. Dawn explains that calcium dysregulation through NMDA receptors plays an upstream role in Alzheimer's pathology. Lithium, a bipolar disorder treatment, can reset deranged calcium gates, inhibiting mitochondrial damage and tau protein production. She emphasizes tau protein as the true culprit in Alzheimer's while amyloid beta is more symptomatic. Correcting calcium homeostasis allows neuronal autophagy systems to clear waste more efficiently rather than being overwhelmed. She reports dramatic peanut allergy declines following 2017 pediatric recommendations for introducing peanuts at 4-6 months based on the LEAP study showing 81% reduction. Between 2017-2020, peanut allergies dropped from 0.79% to 0.45% of all children under 3, with overall food allergies declining 36%. Studies also show pregnant mothers eating peanuts reduces offspring allergy risk by promoting immune tolerance. We conclude with breakthrough wireless retinal implants for macular degeneration, where cameras on glasses convert images to near-infrared signals to retinal implants which stimulate surviving retinal neurons. The prototype allowed patients to improve by two lines on eye charts and perceive facial expressions and read smaller print.
Since Democrats decided to shut down the government over Affordable Care Act subsidies, now's a good time for a deep dive into what they're even talking about. John Hopkins professor Dr. Ge Bai walks us through the ACA subsidies, the hidden mechanics behind the Affordable Care Act, and its illusion of "affordability." Dr. Bai shows us how regulations and subsidies have quietly reshaped the healthcare market - and how the free market can make it work for patients again. Ge Bai, PhD, CPA is a Professor of Accounting at Johns Hopkins Carey Business School and Professor of Health Policy & Management (joint) at Johns Hopkins Bloomberg School of Public Health. An expert on health care accounting, finance, and policy, Dr. Bai has testified before the House Ways and Means Committee and the Senate HELP Committee, written for the Wall Street Journal and the Washington Post, and published her studies in leading academic journals such as the New England Journal of Medicine, JAMA, and Health Affairs. Find her on X at @GeBaiDC and read her recent WSJ oped here: https://www.wsj.com/opinion/let-the-obamacare-enhanced-premium-subsidies-expire-16ef7e1b
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