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Date: November 12, 2025 Reference: Taccone et al. Restrictive vs Liberal Transfusion Strategy in Patients With Acute Brain Injury The TRAIN Randomized Clinical Trial. JAMA 2024 Guest Skeptic: Dr. Alex Weiler is an Emergency Department staff physician in the Peterborough Regional Health Centre and is an associate professor with Queen’s University Department of Family Medicine. […] The post SGEM#492: Give Blood – To Anemic Patients with Acute Brain Injuries first appeared on The Skeptics Guide to Emergency Medicine.
Pour trouver le nom de son mythique espion, l'écrivain Ian Fleming s'est inspiré du nom d'un ornithologue américain. Il stockait d'ailleurs l'un de ses livres dans sa résidence secondaire de Jamaïque. Et vous connaissez tous son nom... GoldenEye. Ça c'est pour le nom de 007 mais pour le personnage, Fleming s'est aussi inspiré d'un homme, un vrai espion ! Il n'était pas Britannique mais Serbe. Et il s'appelait Dusko Popov... Dans "Ah Ouais ?", Florian Gazan répond en une minute chrono à toutes les questions essentielles, existentielles, parfois complètement absurdes, qui vous traversent la tête. Un podcast RTL Originals.Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.
En este episodio, exploramos un fenómeno cada vez más inquietante en las consultas y unidades de neurología: el aumento del ictus en adultos jóvenes. A partir de la evidencia más reciente, analizamos cómo los factores de riesgo clásicos están dando paso a nuevos protagonistas del siglo XXI, entre ellos el estrés crónico. Revisamos el papel del ictus criptogénico, las causas vasculares menos conocidas y los mecanismos por los cuales la sobrecarga emocional, laboral o social puede alterar la fisiología cerebrovascular hasta precipitar un evento agudo. También abordamos la diferencia de impacto entre hombres y mujeres, los hallazgos de estudios internacionales como INTERSTROKE y ERICH, y cómo la gestión del estrés debería considerarse una estrategia real de prevención neurológica. Un episodio para reflexionar sobre la relación entre mente, sociedad y cerebro en una generación que vive —y enferma— bajo presión. Referencias del episodio: 1. Behymer, T. P., Sekar, P., Demel, S. L., Aziz, Y. N., Coleman, E. R., Williamson, B. J., Stanton, R. J., Sawyer, R. P., Turner, A. C., Vagal, V. S., Osborne, J., Gilkerson, L. A., Comeau, M. E., Flaherty, M. L., Langefeld, C. D., & Woo, D. (2025). Psychosocial Stress and Risk for Intracerebral Hemorrhage in the ERICH (Ethnic/Racial Variations of Intracerebral Hemorrhage) Study. Journal of the American Heart Association, 14(6), e024457. https://doi.org/10.1161/JAHA.121.024457 (https://pubmed.ncbi.nlm.nih.gov/40055853/). 2. Egido, J. A., Castillo, O., Roig, B., Sanz, I., Herrero, M. R., Garay, M. T., Garcia, A. M., Fuentes, M., & Fernandez, C. (2012). Is psycho-physical stress a risk factor for stroke? A case-control study. Journal of neurology, neurosurgery, and psychiatry, 83(11), 1104–1110. https://doi.org/10.1136/jnnp-2012-302420 (https://pubmed.ncbi.nlm.nih.gov/22930814/). 3. Gutiérrez-Zúñiga, R., Fuentes, B., & Díez-Tejedor, E. (2018). Ictus criptogénico. Un no diagnóstico. Medicina Clínica, 151 (3), 116-122. https://doi.org/10.1016/j.medcli.2018.01.024 (https://www.sciencedirect.com/science/article/abs/pii/S0025775318300770). 4. Khan, M., Wasay, M., O'Donnell, M. J., Iqbal, R., Langhorne, P., Rosengren, A., Damasceno, A., Oguz, A., Lanas, F., Pogosova, N., Alhussain, F., Oveisgharan, S., Czlonkowska, A., Ryglewicz, D., & Yusuf, S. (2023). Risk Factors for Stroke in the Young (18-45 Years): A Case-Control Analysis of INTERSTROKE Data from 32 Countries. Neuroepidemiology, 57(5), 275–283. https://doi.org/10.1159/000530675 (https://pubmed.ncbi.nlm.nih.gov/37231971/). 5. Kutal, S., Tulkki, L. J., Sarkanen, T., Redfors, P., Jood, K., Nordanstig, A., Yeşilot, N., Sezgin, M., Ylikotila, P., Zedde, M., Junttola, U., Fromm, A., Ryliskiene, K., Licenik, R., Ferdinand, P., Jatužis, D., Kõrv, L., Kõrv, J., Pezzini, A., Sinisalo, J., … Martinez-Majander, N. (2025). Association Between Self-Perceived Stress and Cryptogenic Ischemic Stroke in Young Adults: A Case-Control Study. Neurology, 104(6), e213369. https://doi.org/10.1212/WNL.0000000000213369 (https://pubmed.ncbi.nlm.nih.gov/40043226/). 6. Li, W., Zhang, J., Zhang, Y., Shentu, W., Yan, S., Chen, Q., Qiao, S., & Kong, Q. (2025). Clinical research progress on pathogenesis and treatment of Patent Foramen Ovale-associated stroke. Frontiers in neurology, 16, 1512399. https://doi.org/10.3389/fneur.2025.1512399 (https://pubmed.ncbi.nlm.nih.gov/40291846/). 7. Smyth, A., O'Donnell, M., Hankey, G. J., Rangarajan, S., Lopez-Jaramillo, P., Xavier, D., Zhang, H., Canavan, M., Damasceno, A., Langhorne, P., Avezum, A., Pogosova, N., Oguz, A., Yusuf, S., & INTERSTROKE investigators (2022). Anger or emotional upset and heavy physical exertion as triggers of stroke: the INTERSTROKE study. European heart journal, 43(3), 202–209. https://doi.org/10.1093/eurheartj/ehab738 (https://pubmed.ncbi.nlm.nih.gov/34850877/). 8. Verhoeven, J. I., Fan, B., Broeders, M. J. M., Driessen, C. M. L., Vaartjes, I. C. H., Klijn, C. J. M., & de Leeuw, F. E. (2023). Association of Stroke at Young Age With New Cancer in the Years After Stroke Among Patients in the Netherlands. JAMA network open, 6(3), e235002. https://doi.org/10.1001/jamanetworkopen.2023.5002 (https://pubmed.ncbi.nlm.nih.gov/36976557/). 9. Wegener S. (2022). Triggers of stroke: anger, emotional upset, and heavy physical exertion. New insights from the INTERSTROKE study. European heart journal, 43(3), 210–212. https://doi.org/10.1093/eurheartj/ehab755 (https://pubmed.ncbi.nlm.nih.gov/34850880/). 10. Yaghi, S., Bernstein, R. A., Passman, R., Okin, P. M., & Furie, K. L. (2017). Cryptogenic Stroke: Research and Practice. Circulation research, 120(3), 527–540. https://doi.org/10.1161/CIRCRESAHA.116.308447 (https://pubmed.ncbi.nlm.nih.gov/28154102/). 11. Yang, D., & Elkind, M. S. V. (2023). Current perspectives on the clinical management of cryptogenic stroke. Expert review of neurotherapeutics, 23(3), 213–226. https://doi.org/10.1080/14737175.2023.2192403 (https://pubmed.ncbi.nlm.nih.gov/36934333/).
It's Nurse Practitioners Week, and today, we have a special episode to highlight a historic moment in time. On November 11, the FDA changed the labeling on hormone replacement therapy. Join me for a short, focused episode where I read a recently published JAMA article detailing those changes, to keep you up to date on this significant development. IN THIS EPISODE, YOU WILL LEARN: How recent FDA updates are changing menopausal hormone therapy The history of estrogen's role in heart and bone health How past research sparked fear around hormone therapy What the new labeling means for patients and prescribers How individualized treatment is reshaping dosage and timing decisions. Updated FDA labeling now distinguishes between systemic and topical therapies Key considerations for menopause-related urinary and genital health How these updates will potentially impact women's long-term health Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com
Assalamu'alaikum warahmatullahi wabarakatuh!I hope you all are well. Welcome back to another episode on the Islamic Feelings podcast. This week's episode is a highly requested topic from you all on jealousy, how it shows up in our hearts, and how we can manage it through tazkiyah, self-awareness, and sincere connection to Allah. If you've been struggling with comparison or insecurity, this episode is for you. Al-Lalaka'i reported: Abu Darda, may Allah be pleased with him, said, “The pinnacle of faith is in four things: patience with the judgment of Allah, pleasure with the decree of Allah, sincerity and trust in Allah, and surrender to the Lord.”Source: Sharḥ Uṣūl I'tiqād Ahl al-Sunnah wal-Jamā'ah 1697
Editor's Summary by Linda Brubaker, MD, and Preeti Malani, MD, MSJ, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from November 8-14, 2025. Related Content: From AHA: Coffee Consumption and Atrial Fibrillation, DASH-Patterned Groceries and Effects on Blood Pressure, Oral PCSK9 Inhibitor Enlicitide for Heterozygous Familial Hypercholesterolemia, and more
Un nouvel épisode du Pharmascope est maintenant disponible! Dans de ce 113ème épisode, Sébastien, Nicolas et Isabelle débutent une série d'épisodes sur l'ostéoporose. Dans ce premier épisode, on aborde le dépistage, l'évaluation et le diagnostic de l'ostéoporose, une maladie qui n'en est peut-être pas vraiment une… Les objectifs pour cet épisode sont les suivants: Définir l'ostéoporose Identifier les patients nécessitant un dépistage de l'ostéoporose Expliquer les avantages et les limites d'une ostéodensitométrie Évaluer le risque de fracture d'un patient Ressources pertinentes en lien avec l'épisode National Institute for Health and Care Excellence (NICE). Osteoporosis: assessing the risk of fragility fracture. London; 2017. US Preventive Services Task Force. Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement. JAMA. 2018;319:2521-31. Viswanathan M et coll. Screening to Prevent Osteoporotic Fractures: An Evidence Review for the U.S. Preventive Services Task Force. Rockville (MD): Agency for Healthcare Research and Quality (US); 2018. (Evidence Synthesis, No. 162. Papaioannou A et coll. 2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary. CMAJ. 2010;182:1864-73. Korownyk C, McCormack J, Allan GM. Who should receive bone mineral density testing? Can Fam Physician. 2015;61:612. Choisir avec soin. L'ostéodensitométrie. Canada. Management of Osteoporosis in Postmenopausal Women: The 2021 Position Statement of The North American Menopause Society'' Editorial Panel. Management of osteoporosis in postmenopausal women: the 2021 position statement of The North American Menopause Society. Menopause. 2021;28:973-97. Calculateur FRAX Centre for Metabolic Bone Diseases. FRAX: Fracture Risk Assessment Tool. University of Sheffield, UK.
Interview with Kristine A. Smith, MD, author of Evaluation of Practice Patterns for 6-Sinus Balloon Sinus Dilation; Jay F. Piccirillo, MD, author of Balloon Sinus Dilation Use; and Donald C. Lanza, MD, MS, author of Balloon Sinus Dilation—To Inflate or Not to Inflate. Hosted by Paul C. Bryson, MD, MBA. Related Content: Evaluation of Practice Patterns for 6-Sinus Balloon Sinus Dilation Balloon Sinus Dilation—To Inflate or Not to Inflate Balloon Sinus Dilation Use
Interview with Elizabeth J. Phillips, MD, author of Recovering From Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis. Hosted by Adewole S. Adamson, MD. Related Content: Recovering From Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
Overview: In this episode, Dr Toyin Nwafor and Dr Andrew Zolopa provide an overview of the HIV treatment landscape both globally and in the United States. They highlight the current gaps in the HIV care continuum, emphasize the importance of rapid start and viral suppression in reducing HIV transmission through sex and describe initiatives and strategies aimed at closing these gaps to help end the HIV epidemic in the United States. The views expressed are those of the panelist(s) and not necessarily Gilead Sciences, Inc. The information provided in this podcast is not intended to be and should not be understood to provide medical advice. Listeners should note that our discussions in this episode are relevant to the USA only and may not be appropriate for other regions. This episode was recorded in August 2025 and the content reflects the information available at that time. Guest: Toyin Nwafor, MD; Andrew Zolopa, MD For more information, please visit: https://www.pri-med.com/clinical-resources/curriculum/hiv-in-focus References AETC. Rapid (immediate) ART initiation and restart: guide for clinicians. 2023. Available from: https://aidsetc.org/resource/rapid-immediate-art-initiation-restart-guide-clinicians (Accessed June 25, 2025). Baxter A et al. J Acquir Immune Defic Syndr 2025;99:47–54. CDC. About ending the HIV epidemic in the US. 2024. Available from: https://www.cdc.gov/ehe/php/about/index.html (Accessed June 25, 2025). CDC. Clinical testing guidance for HIV. 2025. Available from: https://www.cdc.gov/hivnexus/hcp/diagnosis-testing/index.html (Accessed June 25, 2025). CDC. Getting tested for HIV. 2025. Available from: https://www.cdc.gov/hiv/testing/index.html#cdc_testing_why_get_tested-why-get-tested (Accessed June 25, 2025). CDC. Laboratory testing for the diagnosis of HIV infection. 2014. Available from: https://stacks.cdc.gov/view/cdc/23446 (Accessed June 25, 2025). CDC. National HIV prevention and care objectives: 2025 update. 2025. Available from: https://www.cdc.gov/hiv-data/nhss/national-hiv-prevention-and-care-objectives-2025.html (Accessed June 25, 2025). Delaney KP et al. Am J Prev Med 2021;61(5 Suppl 1):S6–S15. DHHS. Guidelines for the use of antiretroviral agents in adults and adolescents living with HIV. 2024. Available from: https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/adult-adolescent-arv/guidelines-adult-adolescent-arv.pdf (Accessed June 25, 2025). HIV.gov. EHE overview. 2025. Available from: https://www.hiv.gov/federal-response/ending-the-hiv-epidemic/overview (Accessed June 25, 2025). HIV.gov. Global statistics. 2025. Available from: https://www.hiv.gov/hiv-basics/overview/data-and-trends/global-statistics (Accessed June 25, 2025). HIV.gov. HIV Care Continuum. 2025. Available from: https://www.hiv.gov/federal-response/other-topics/hiv-aids-care-continuum (Accessed June 25, 2025). HIV.gov. Key EHE strategies. 2024. Available from: https://www.hiv.gov/federal-response/ending-the-hiv-epidemic/key-strategies (Accessed June 25, 2025). HIV.gov. US statistics. 2025. Available from: https://www.hiv.gov/hiv-basics/overview/data-and-trends/statistics (Accessed June 25, 2025). HIV.gov. Viral suppression and undetectable viral load. 2025. Available from: https://www.hiv.gov/hiv-basics/staying-in-hiv-care/hiv-treatment/viral-suppression (Accessed June 25, 2025). Mirzazadeh A et al. PLoS Med 2022;19:e1003940. NIH. HIV testing. 2025. Available from: https://hivinfo.nih.gov/understanding-hiv/fact-sheets/hiv-testing (Accessed June 25, 2025). Palacio-Vieira J et al. BMC Public Health 2021;21:1596. Saag MS et al. JAMA 2018;320:379–96. The White House. National HIV/AIDS strategy for the United States 2022–2025. 2021. Available from: https://files.hiv.gov/s3fs-public/NHAS-2022-2025.pdf (Accessed June 25, 2025). WHO. Supporting re-engagement in HIV treatment services: policy brief. 2024. Available from: https://www.who.int/publications/i/item/9789240097339 (Accessed June 25, 2025).
Overview: In this episode, Dr Gina Brown and Dr Sahar Khalili draw on their expertise in HIV prevention to provide an overview of the current PrEP landscape in the United States. They highlight advancements in HIV prevention and emphasize the importance of targeted programs to address disparities in access and uptake across population groups and geographic regions. The views expressed are those of the panelist(s) and not necessarily Gilead Sciences, Inc. The information provided in this podcast is not intended to be and should not be understood to provide medical advice. Listeners should note that our discussions in this episode are relevant to the USA only and may not be appropriate for other regions. This episode was recorded in August 2025 and the content reflects the information available at that time. Guest: Gina Brown, MD; Sahar Khalili, PharmD For more information, please visit: https://www.pri-med.com/clinical-resources/curriculum/hiv-in-focus References ACOG. Preexposure prophylaxis for the prevention of human immunodeficiency virus. 2024. Available from: https://www.acog.org/clinical/clinical-guidance/practice-advisory/articles/2022/06/preexposure-prophylaxis-for-the-prevention-of-human-immunodeficiency-virus (Accessed June 25, 2025). ADAP Directory. About. 2024. Available from: https://adap.directory/about (Accessed June 25, 2025). Aidsmap. Condoms. 2023. Available from: https://www.aidsmap.com/about-hiv/condoms#toc-how-effective-are-condoms (Accessed June 25, 2025). AIDSVu. AIDSVu releases new PrEP data and launches PrEPVu.org, a new PrEP equity platform. 2024. Available from: https://aidsvu.org/news-updates/aidsvu-releases-new-prep-data-and-launches-prepvu-org-a-new-prep-equity-platform/ (Accessed June 25, 2025). AIDSVu.org was developed by the Rollins School of Public Health at Emory University in partnership with Gilead Sciences, Inc. AIDSVu. AIDSVu releases 2024 PrEP use data showing growing use across the U.S. 2025. Available from: https://aidsvu.org/news-updates/aidsvu-releases-2024-prep-use-data-showing-growing-use-across-the-u-s/ (Accessed July 18, 2025). AIDSVu.org was developed by the Rollins School of Public Health at Emory University in partnership with Gilead Sciences, Inc. AIDSVu. Location profiles: South. 2025. Available from: https://map.aidsvu.org/profiles/region/south/prevention-and-testing#1-2-PnR (Accessed July 31, 2025). AIDSVu.org was developed by the Rollins School of Public Health at Emory University in partnership with Gilead Sciences, Inc. AIDSVu. PrEP use significantly associated with decreasing new HIV diagnoses across U.S. states. 2025. Available from: https://aidsvu.org/news-updates/prep-use-significantly-associated-with-decreasing-new-hiv-diagnoses-across-u-s-states/ (Accessed June 25, 2025). AIDSVu.org was developed by the Rollins School of Public Health at Emory University in partnership with Gilead Sciences, Inc. Baeten J et al. Curr HIV/AIDS Rep 2013;10:142–51. Bekker LG et al. N Engl J Med 2024;391:1179–92. CDC. About ending the HIV epidemic in the US. 2024. Available from: https://www.cdc.gov/ehe/php/about/index.html (Accessed June 2, 2025). CDC. Clinical Guidance for PrEP. 2025. Available from: https://www.cdc.gov/hivnexus/hcp/prep/index.html (Accessed June 25, 2025). CDC. Preexposure prophylaxis for the prevention of HIV infection in the United States - 2021 update. 2021. Available from: https://stacks.cdc.gov/view/cdc/112360 (Accessed June 25, 2025). Coates TJ et al. Lancet 2008;372:669–84. DHHS. Pre-exposure (PrEP) to prevent HIV during periconception, antepartum, ad postpartum. 2024. Available from: https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/perinatal-hiv/pre-exposure-prophylaxis-prep-prevent-hiv-perinatal.pdf (Accessed June 25, 2025). Gandhi RT et al. JAMA 2023;329:63–84. HIV.gov. HIV treatment as prevention. 2023. Available from: https://www.hiv.gov/tasp (Accessed June 25, 2025). HIV.gov. Key EHE strategies. 2024. Available from: https://www.hiv.gov/federal-response/ending-the-hiv-epidemic/key-strategies (Accessed June 2, 2025). HIV.gov. Pre-exposure prophylaxis. 2025. Available from: https://www.hiv.gov/hiv-basics/hiv-prevention/using-hiv-medication-to-reduce-risk/pre-exposure-prophylaxis (Accessed June 25, 2025). Kelley CF et al. N Engl J Med 2025;392:1261–76. Kourtis AP et al. Ann Epidemiol 2025:106:48-54. Landers S et al. Am J Public Health 2017;107:1534–35. Landovitz RJ et al. N Engl J Med 2021;385:595–608. NIH. HIV and sexually transmitted infections (STIs). 2021. Available from: https://hivinfo.nih.gov/understanding-hiv/fact-sheets/hiv-and-sexually-transmitted-diseases-stds (Accessed June 25, 2025). NIH. HIV medicines during pregnancy and childbirth. 2025. Available from: https://hivinfo.nih.gov/understanding-hiv/fact-sheets/hiv-medicines-during-pregnancy-and-childbirth (Accessed July 31, 2025) NIH. Post-exposure prophylaxis (PEP). 2025. Available from: https://hivinfo.nih.gov/understanding-hiv/fact-sheets/post-exposure-prophylaxis-pep (Accessed June 25, 2025). NIH. PrEP to prevent HIV and promote sexual health. 2022. Available from: https://www.ncbi.nlm.nih.gov/books/NBK556471/ (Accessed June 25 2025). Siegler AJ et al. Ann Epidemiol 2020;45:24–31.e37 Sullivan PS et al. J Int AIDS Soc 2025;28:e26459. Townes A et al. Obstet Gynecol 2023;143:294–301. Underhill K et al. PLoS Med 2007;4:e275. United States Census Bureau. National population by characteristics: 2020–2024. 2024. Available from: https://www.census.gov/data/tables/time-series/demo/popest/2020s-national-detail.html (Accessed June 25, 2025). Owens DK et al. JAMA 2019;321:2326–36. Vermund SH et al. J Acquir Immune Defic Syndr 2013;63:S12–25. Washington State Department of Health. Pre-exposure prophylaxis drug assistance program (PrEP DAP). Available from: https://doh.wa.gov/you-and-your-family/illness-and-disease-z/hiv/prevention/pre-exposure-prophylaxis-drug-assistance-program-prep-dap (Accessed June 25, 2025). World Health Organization. Global HIV programme: pre-exposure prophylaxis (PrEP). Available from: https://www.who.int/teams/global-hiv-hepatitis-and-stis-programmes/hiv/prevention/pre-exposure-prophylaxis (Accessed June 25, 2025).
Overview: In this episode, Toyin Nwafor, MD, and Christian B Ramers, MD, draw on their experience in primary care, HIV and HIV prevention to highlight missed opportunities for HIV prevention and discuss strategies to help address gaps in the HIV care continuum. The views expressed are those of the panelist(s) and not necessarily Gilead Sciences, Inc. The information provided in this podcast is not intended to be and should not be understood to provide medical advice. Listeners should note that our discussions in this episode are relevant to the USA only and may not be appropriate for other regions. This episode was recorded in August 2025 and the content reflects the information available at that time. Guest: Toyin Nwafor, MD; Christian B Ramers, MD, MPH, FIDSA, AAHIVS For more information, please visit: https://www.pri-med.com/clinical-resources/curriculum/hiv-in-focus References AIDSVu.org. Prevalence in the United States. 2022. Available from: https://map.aidsvu.org/ (Accessed June 25, 2025). AIDSVu.org was developed by the Rollins School of Public Health at Emory University in partnership with Gilead Sciences, Inc. Baeten J et al. Curr HIV/AIDS Rep 2013;10:142–51. CDC. Clinical testing guidance for HIV. 2025. Available from: https://www.cdc.gov/hivnexus/hcp/diagnosis-testing/index.html (Accessed June 25, 2025). CDC. Discussing sexual health with your patients. 2025. Available from: https://www.cdc.gov/hivnexus/hcp/sexual-history/index.html (Accessed June 25, 2025). CDC.gov. HIV diagnoses, deaths, and prevalence. 2025. Available from: https://www.cdc.gov/hiv-data/nhss/hiv-diagnoses-deaths-prevalence.html (Accessed June 25, 2025). CDC. National HIV prevention and care objectives: 2025 update. 2025. Available from: https://www.cdc.gov/hiv-data/nhss/national-hiv-prevention-and-care-objectives-2025.html (Accessed June 25, 2025). CDC. Preexposure prophylaxis for the prevention of HIV infection in the United States – 2021 update: a clinical practice guideline. 2021. Available from: https://stacks.cdc.gov/view/cdc/112360 (Accessed June 25, 2025). Doblecki-Lewis S et al. J Int Assoc Provid AIDS Care 2019;18:2325958219848848. DHHS. Guidelines for the use of antiretroviral agents in adults and adolescents with HIV. 2024. Available from: https://clinicalinfo.hiv.gov/sites/default/files/guidelines/documents/adult-adolescent-arv/guidelines-adult-adolescent-arv.pdf (Accessed June 25, 2025). HIV.gov. Key EHE strategies. 2024. Available from: https://www.hiv.gov/federal-response/ending-the-hiv-epidemic/key-strategies (Accessed June 2, 2025). HIV.gov. HIV treatment as prevention. 2023. Available from: https://www.hiv.gov/tasp (Accessed June 25, 2025). HIV.gov. US statistics. 2025. Available from: https://www.hiv.gov/hiv-basics/overview/data-and-trends/statistics (Accessed May 21, 2025). HIV.gov. Viral suppression and undetectable viral load. 2025. Available from: https://www.hiv.gov/hiv-basics/staying-in-hiv-care/hiv-treatment/viral-suppression (Accessed July 18, 2025). HIV.gov. Who is at risk for HIV. 2025. Available from: https://www.hiv.gov/hiv-basics/overview/about-hiv-and-aids/who-is-at-risk-for-hiv (Accessed June 25, 2025). Johns Hopkins Bloomberg School of Public Health. What to know about PrEP. 2025. Available from: https://publichealth.jhu.edu/2025/who-needs-prep-for-hiv-prevention (Accessed June 25, 2025). Kamis KF et al. Open Forum Infect Dis 2019;6:ofz310. KFF. HIV testing in the United States. 2024. Available from: https://www.kff.org/hiv-aids/hiv-testing-in-the-united-states/ting in the United States | KFF (Accessed August 26, 2025). NIH. HIV and sexually transmitted infections (STIs). 2021. Available from: https://hivinfo.nih.gov/understanding-hiv/fact-sheets/hiv-and-sexually-transmitted-infections-stis (Accessed June 25, 2025). Ramchandani MS et al. Curr HIV/AIDS Rep 2019;16:244–56. Saag MS et al. JAMA 2018;320:379–96. Sweeney P et al. J Acquir Immune Defic Syndr 2019;82(Suppl 1):S1–5. The White House. National HIV/AIDS strategy for the United States 2022–2025. 2021. Available from: https://files.hiv.gov/s3fs-public/NHAS-2022-2025.pdf (Accessed June 25, 2025). UNAIDS.org. Recommended 2030 targets for HIV. 2025. Available from: https://www.unaids.org/en/recommended-2030-targets-for-hiv (Accessed August 26, 2025). United States Census Bureau. National population by characteristics: 2020-2024. 2024. Available from: https://www.census.gov/data/tables/time-series/demo/popest/2020s-national-detail.html (Accessed June 25, 2025). United States Census Bureau. United States Population Growth by Region. 2025. Available from: https://www.census.gov/popclock/ (Accessed June 25, 2025). Yumori C et al. Sex Transm Dis 2021;48:32–6.
Today's HeadlinesTerrorists tightening their grip on MaliPeople displaced, livestock lost, crops destroyed — how Typhoon Kalmaegi devastated Vietnam
About this Episode Episode 50 of “The 2 View” – BNPs, D-Dimers, and Sneakily Sick Kids Segment 1A - Needs of older nurses Clendon JA, Walker L. Nurses aged over 50 and their perceptions of flexible working: The experiences and needs of older nurses in relation to flexible working and the barriers and facilitators to implementation within workplaces. J Nurs Manag. 2016;24:336-346. doi:10.1111/jonm.12325 Segment 1B - WHO and Tropical Diseases Special Programme for Research and Training in Tropical Diseases. World Health Organization. Accessed August 19, 2025. https://tdr.who.int/about-us Segment 2A - BNP Silvers SM, Gemme SR, Hickey S, et al. Clinical Policy: Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Heart Failure Syndromes. Ann Emerg Med. 2019;49(2): 232–241. Lamberta M, Chertoff A. BNP Level in the Emergency Department: Does it Change Management? EMDocs. June 20, 2016. Accessed November 4, 2025. https://www.emdocs.net/bnp-level-in-the-emergency-department-does-it-change-management/ Maisel AS, Krishnaswamy P, Nowak RM, et al. Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure. N Engl J Med. 2002;347(3):161-167. doi: 10.1056/NEJMoa020233 Segment 2B - D-Dimer Wolf SJ, Hahn SA, Nentwich LM, et al. Clinical policy: Critical issues in the evaluation and management of adult patients presenting to the emergency department with suspected acute venous thromboembolic disease. Ann Emerg Med. 2018;71(5):e59–e109. doi:10.1016/j.annemergmed.2018.03.006 Righini M, Van Es J, Den Exter PL, et al. Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: The ADJUST-PE study. JAMA. 2014;311(11):1117–1124. doi:10.1001/jama.2014.2135 van der Hulle T, Cheung WY, Kooij S, et al. Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): A prospective, multicentre, cohort study. Lancet. 2017;390(10091):289–297. doi:10.1016/S0140-6736(17)30885-1 Kearon C, de Wit K, Parpia S, et al. Diagnosis of pulmonary embolism with D-dimer adjusted to clinical probability. N Engl J Med. 2019;381(22):2125–2134. doi:10.1056/NEJMoa1909159 Lim w, Le Gal G, Bates SM, et al. American Society of Hematology 2018 guidelines for management of venous thromboembolism: Diagnosis of venous thromboembolism. Blood Adv. 2018;2(22):3226-3256. doi:10.1182/bloodadvances.2018024828 Kabrhel C, Jaff MR, Channick RN. D-dimer. StatPearls. June 22, 2025. Accessed November 4, 2025. https://www.ncbi.nlm.nih.gov/books/NBK431064/ Tripodi A, Lippi G. How we manage a high D-dimer. Haematologica. 2020;106(6):1491-1494. doi:10.3324/haematol.2020.248344 Segment 3: Sneakily Sick Kids Kocher MS, Zurakowski D, Kasser JR. Differentiating between septic arthritis and transient synovitis of the hip in children: An evidence-based clinical prediction algorithm. J Bone Joint Surg Am. 1999;81(12):1662-1670. doi:10.2106/00004623-199912000-00002 Caird MS, Flynn JM, Leung YL, et al. Factors distinguishing septic arthritis from transient synovitis of the hip in children: a prospective study. J Bone Joint Surg Am. 2006;88(6): 1251-1257. doi:10.2106/JBJS.E.00216 Recurring Sources Center for Medical Education. http://ccme.org The Proceduralist. http://www.theproceduralist.org The Procedural Pause. https://journals.lww.com/em-news/blog/theproceduralpause/pages/default.aspx The Skeptics Guide to Emergency Medicine. http://www.thesgem.com Be sure to keep tuning in for more great prizes and fun trivia questions! Once you hear the question, please email us your guesses at 2viewcast@gmail.com and tell us who you want to give a shout-out to.
Send us a message with this link, we would love to hear from you. Standard message rates may apply.We break down osteopenia and osteoporosis with clear steps to protect independence: how bones weaken, how DEXA scoring works, and which daily habits reduce fracture risk. We share nutrition, exercise, lifestyle changes, and home safety that make a measurable difference.• key stats on fracture risk in women and men over 50• definitions of osteopenia and osteoporosis using T-scores• hip, spine and wrist as common fracture sites• why bone loss accelerates after menopause• risk factors including family history, smoking and low weight• DEXA scan basics and when to ask for screening• calcium and vitamin D targets and food sources• Mediterranean diet, protein and supportive micronutrients• weight-bearing, resistance and balance training essentials• Tai Chi and fall risk reduction• home safety changes that prevent falls• when medications like bisphosphonates or denosumab help• practical questions to ask your clinicianReferences1. Osteoporosis: Common Questions and Answers. Harris K, Zagar CA, Lawrence KV. American Family Physician. 2023;107(3):238-246.2. Postmenopausal Osteoporosis. Walker MD, Shane E. The New England Journal of Medicine. 2023;389(21):1979-1991. doi:10.1056/NEJMcp2307353.3. American Association of Clinical Endocrinologists/American College of Endocrinology Clinical Practice Guidelines for the Diagnosis and Treatment of Postmenopausal Osteoporosis-2020 Update. Camacho PM, Petak SM, Binkley N, et al. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 2020;26(Suppl 1):1-46. doi:10.4158/GL-2020-0524SUPPL.4. Global, Regional Prevalence, and Risk Factors of Osteoporosis According to the World Health Organization Diagnostic Criteria: A Systematic Review and Meta-Analysis. Xiao PL, Cui AY, Hsu CJ, et al. Osteoporosis International : A Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 2022;33(10):2137-2153. doi:10.1007/s00198-022-06454-3.5. Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement. Curry SJ, Krist AH, Owens DK, et al. JAMA. 2018;319(24):2521-2531. doi:10.1001/jama.2018.7498.6. The Cost of Osteoporosis, Osteopenia, and Associated Fractures in Australia in 2017. Tatangelo G, Watts J, Lim K, et al. Journal of Bone and Mineral Research : The Official Journal of the American Society for Bone and Mineral Research. 2019;34(4):616-625. doi:10.1002/jbmr.3640.7. The Prevalence and Treatment Rate Trends of Osteoporosis in Postmenopausal Women. Zhang X, Wang Z, Zhang D, et al. PloS One. 2023;18(9):e0290289. doi:10.1371/journal.pone.0290289.8. Osteopenia: A Key Target for Fracture Prevention. Reid IR, McClung MR. The Lancet. Diabetes & Endocrinology. 2024;12(11):856-864. doi:10.1016/S2213-8587(24)00225-0.9. Effectiveness and Safety of Treatments to Prevent Fractures in People With Low Bone Mass or Primary Osteoporosis: A Living Systematic Review and Network Meta-Analysis for the American College of Physicians. Ayers C, Kansagara D, Lazur B, et al. Annals of Internal Medicine. 2023;176(2):182-195. doi:10.7326/M22-0684.Support the showSubscribe to Our Newsletter! Production and Content: Edward Delesky, MD & Nicole Aruffo, RNArtwork: Olivia Pawlowski
Recently, a new version of the Sequential Organ Failure Assessment (SOFA) score was introduced.Known as SOFA-2, this new definition aligns with organ dysfunction measurement in critically ill adults with current clinical practices, especially those diagnosed with sepsis.Published in the Journal of the American Medical Association (JAMA) on Oct. 29 and available at https://jamanetwork.com/journals/jama/fullarticle/2840822, this revised tool updates the original 1996 SOFA score, which had remained unchanged despite evolving treatment modalities and technologies. During the next live edition of Monitor Mondays, Dr. James S. Kennedy will discuss this SOFA-2 revision and its expected impact on clinical validation for sepsis – defined by Sepsis-3 as a life-threatening organ dysfunction caused by a dysregulated host response to infection – and how facility clinical workflows can negotiate denial avoidance with payers with this challenging diagnosis.The weekly broadcast will also include these instantly recognizable features:Monday Rounds: Ronald Hirsch, MD, vice president of R1 RCM, will be making his Monday Rounds.The RAC Report: Healthcare attorney Knicole Emanuel, partner at the law firm of Nelson Mullins, will report the latest news about auditors.Risky Business: Healthcare attorney David Glaser, shareholder in the law offices of Fredrikson & Byron, will join the broadcast with his trademark segment.Legislative Update: Cate Brantley, senior healthcare legislative affairs analyst for Zelis, will report on the news happening at the intersection of healthcare and congressional action.
Usain Bolt, né en Jamaïque, rêve d'abord de cricket avant d'être propulsé sur les pistes d'athlétisme. Dès l'adolescence, il domine les compétitions juniors et explose lors des JO de Pékin 2008 avec un triplé olympique et des records du monde. Surnommé "La Foudre", il confirme son règne à Berlin, Londres et Rio. Mais en 2011, un faux départ aux mondiaux le disqualifie du 100 mètres, marquant sa première chute. Il rebondit avec éclat sur 200 m et en relais. En 2017, à Londres, sa dernière course se termine sur une défaite. Blessé, il quitte la scène sur un échec, mais entre dans la légende avec 8 médailles d'or olympiques. Il tente une reconversion dans le football, sans succès. Bolt reste l'un des plus grands champions de l'Histoire du sport. Merci pour votre écoute Vous aimez l'Heure H, mais connaissez-vous La Mini Heure H https://audmns.com/YagLLiK , une version pour toute la famille.Retrouvez l'ensemble des épisodes de l'Heure H sur notre plateforme Auvio.be :https://auvio.rtbf.be/emission/22750 Intéressés par l'histoire ? Vous pourriez également aimer nos autres podcasts : Un jour dans l'Histoire : https://audmns.com/gXJWXoQL'Histoire Continue: https://audmns.com/kSbpELwAinsi que nos séries historiques :Chili, le Pays de mes Histoires : https://audmns.com/XHbnevhD-Day : https://audmns.com/JWRdPYIJoséphine Baker : https://audmns.com/wCfhoEwLa folle histoire de l'aviation : https://audmns.com/xAWjyWCLes Jeux Olympiques, l'étonnant miroir de notre Histoire : https://audmns.com/ZEIihzZMarguerite, la Voix d'une Résistante : https://audmns.com/zFDehnENapoléon, le crépuscule de l'Aigle : https://audmns.com/DcdnIUnUn Jour dans le Sport : https://audmns.com/xXlkHMHSous le sable des Pyramides : https://audmns.com/rXfVppvVous aimez les histoires racontées par Jean-Louis Lahaye ? Connaissez-vous ces podcast?Sous le sable des Pyramides : https://audmns.com/rXfVppv36 Quai des orfèvres : https://audmns.com/eUxNxyFHistoire Criminelle, les enquêtes de Scotland Yard : https://audmns.com/ZuEwXVOUn Crime, une Histoire https://audmns.com/NIhhXpYN'oubliez pas de vous y abonner pour ne rien manquer.Et si vous avez apprécié ce podcast, n'hésitez pas à nous donner des étoiles ou des commentaires, cela nous aide à le faire connaître plus largement. Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.
In this episode of Hold Your Fire!, Richard is joined by Crisis Group's Cameroon expert Arrey E. Ntui and Sahel director Jean-Hervé Jézéquel. Richard first talks with Arrey about the fallout from Cameroon's disputed elections, growing public anger toward President Paul Biya – the world's oldest serving head of state – and opposition protests. They also assess how the political crisis might affect Cameroon's long-running Anglophone conflict and risks for further escalation. Richard then turns to Jean-Herve to discuss the blockade imposed by the militant group Jama'at Nusrat al-Islam wal-Muslimin (JNIM), which has cut off fuel supplies to the capital Bamako. They examine why the military has struggled to secure key supply roads, whether the blockade signals a shift in JNIM's strategy, how it might shape public sentiment toward Mali's military rulers and whether the blockade paves the way for a jihadist takeover.Click here to listen on Apple Podcasts or Spotify. For more, check out our Cameroon and Mali pages. Hosted on Acast. See acast.com/privacy for more information.
Broadcast from KSQD, Santa Cruz on 11-06-2025:>/p> Dr. Dawn interviews Cindy Jackonette and Dr. Michael Alexander about a fundraiser for pancreatic cancer awareness on November 15th at Bargetto Winery from 2-5pm, supporting the Santa Cruz Cancer Benefit Group. Dr. Alexander explains pancreatic cancer has only 10-15% five-year survival rates and is difficult to screen for. Screening involves complex endoscopy procedures examining pancreatic ducts, CT scans and biomarker scans. The disease represents 3% of cancer cases but 8% of deaths. Immune checkpoint inhibitors show limited success except in Lynch syndrome patients with DNA repair defects. The Santa Cruz Cancer Benefit Group donates annually to local cancer organizations and is all volunteer-run with minimal overhead. An emailer asks when her 56-year-old half-African American son should get colon cancer screening given his father and uncle both had the disease. Dr. Dawn explains African Americans have increased risk and recommends immediate colonoscopy despite the ideal screening window being 10 years ago. She emphasizes identifying whether he produces polyps, which would require surveillance every 3-5 years. Unlike pancreatic cancer, colon cancer is highly curable when detected early, with death rates dropping 30-40% since colonoscopies became standard in the mid-1990s. She recommends preventive measures including daily 200mg ibuprofen (if no ulcer history) and a high-fiber diet rich in colorful vegetables containing antioxidants that reduce oxidative stress and DNA damage from free radicals. An emailer from Israel asks about supporting his 38-year-old son's rectal adenocarcinoma treatment. Dr. Dawn recommends nutritional strategies including juicing 10 different fruits and vegetables daily, 20mg melatonin for synergy with chemotherapy, vitamin D supplementation, and L-glutamine as primary food for bowel healing and lymphocyte function. She suggests DHA fish oil to enhance chemotherapy effectiveness, green tea for oncogene inhibition, astragalus herb to increase phagocytic activity and natural killer cells, and rotating water-extracted mushroom formulas with beta-glucans, particularly maitake and shitake. Glutamine also protects mucous membranes from radiation burns. Dr. Dawn discusses alarming cancer rate increases among young adults in Corn Belt states including Iowa, Nebraska, Illinois, Minnesota, Indiana, and Kansas. Since 2015, these states show 5% higher cancer rates for ages 15-49 compared to national averages, with particularly elevated kidney and skin cancer rates. Young women face 66% higher skin cancer risk than peers in other states. . Governor Kim Reynolds invested $1 million for research while Bayer's attempt to shield Roundup from lawsuits failed. Dr. Dawn notes Roundup now contains diquat after removing glyphosate. It has taken decades to accumulate evidence of glyphosates harms, She warns that absence of evidence of Diquats being harmful isn't evidence of safety and that Ames testing suggests high mutation potential. An emailer shares a JAMA article on lithium for Alzheimer's disease. Dr. Dawn explains that calcium dysregulation through NMDA receptors plays an upstream role in Alzheimer's pathology. Lithium, a bipolar disorder treatment, can reset deranged calcium gates, inhibiting mitochondrial damage and tau protein production. She emphasizes tau protein as the true culprit in Alzheimer's while amyloid beta is more symptomatic. Correcting calcium homeostasis allows neuronal autophagy systems to clear waste more efficiently rather than being overwhelmed. She reports dramatic peanut allergy declines following 2017 pediatric recommendations for introducing peanuts at 4-6 months based on the LEAP study showing 81% reduction. Between 2017-2020, peanut allergies dropped from 0.79% to 0.45% of all children under 3, with overall food allergies declining 36%. Studies also show pregnant mothers eating peanuts reduces offspring allergy risk by promoting immune tolerance. We conclude with breakthrough wireless retinal implants for macular degeneration, where cameras on glasses convert images to near-infrared signals to retinal implants which stimulate surviving retinal neurons. The prototype allowed patients to improve by two lines on eye charts and perceive facial expressions and read smaller print.
Editor's Summary by Linda Brubaker, MD, and Preeti Malani, MD, MSJ, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from November 1-7, 2025.
La Playlist du dimanche 2 novembre 2025 L'article Crossover – A’Dam to Jamaïca est apparu en premier sur Radio Campus Tours - 99.5 FM.
Since Democrats decided to shut down the government over Affordable Care Act subsidies, now's a good time for a deep dive into what they're even talking about. John Hopkins professor Dr. Ge Bai walks us through the ACA subsidies, the hidden mechanics behind the Affordable Care Act, and its illusion of "affordability." Dr. Bai shows us how regulations and subsidies have quietly reshaped the healthcare market - and how the free market can make it work for patients again. Ge Bai, PhD, CPA is a Professor of Accounting at Johns Hopkins Carey Business School and Professor of Health Policy & Management (joint) at Johns Hopkins Bloomberg School of Public Health. An expert on health care accounting, finance, and policy, Dr. Bai has testified before the House Ways and Means Committee and the Senate HELP Committee, written for the Wall Street Journal and the Washington Post, and published her studies in leading academic journals such as the New England Journal of Medicine, JAMA, and Health Affairs. Find her on X at @GeBaiDC and read her recent WSJ oped here: https://www.wsj.com/opinion/let-the-obamacare-enhanced-premium-subsidies-expire-16ef7e1b
La inflamación silenciosa o de bajo grado es uno de los procesos más estudiados de los últimos años, y se ha convertido en la base común de muchas patologías modernas: desde la resistencia a la insulina, el hígado graso o las enfermedades cardiovasculares, hasta trastornos del ánimo, alteraciones digestivas o incluso ciertos tipos de cáncer. En este episodio te explico qué es exactamente esta inflamación crónica, qué la causa y por qué puede pasar desapercibida durante años. Hablaremos del papel del estrés, el sueño, la microbiota, la alimentación y el sedentarismo, y de cómo pequeños cambios en tu estilo de vida pueden reducir los marcadores inflamatorios y mejorar tu salud a largo plazo. Una guía completa para entender qué significa realmente “comer y vivir de forma antiinflamatoria” y por qué este enfoque puede marcar la diferencia entre tener energía o arrastrar cansancio constante, entre salud y enfermedad.
Did you know most doctors receive almost no formal training in nutrition? In this eye-opening episode, Dr. Sabrina Falquier sits down with internal medicine specialist, Dr. Thomas Carter, and third year medical student, Megan Roach, for an honest conversation about how much nutrition has been taught in medical school and what that means for patient care. Together, they compare experiences, share insights from both generations of medicine, and discuss why culinary medicine is helping bridge the knowledge gap. In this episode you'll hear:1:00 – How much nutrition is taught in medical school?8:20 – Why Dr. Carter agreed to be a guest on this episode10:00 – Nutrition education in medical school: Megan Roach's perspective as a medical student13:00 – Culinary medicine workshops in medical school14:20 – Food as medicine15:00 – What every medical student should learn about nutrition17:00 – The challenge of speaking with patients about nutrition19:30 – What Dr. Carter wishes he knew about nutrition21:00 – How do you talk to a patient about nutrition?26:45 – How to give nutrition advice in short appointments31:30 – Nutrition training: The hope for future doctorsReferenced in the episode:Proposed Nutrition Competencies for Medical Students and Physician TraineesMedicina Culinaria podcast in SpanishBuy Me a CoffeeCredits:Host – Dr. Sabrina Falquier, MD, CCMS, DipABLMSound and Editing – Will CrannExecutive Producer – Esther Garfin©2025 Alternative Food Network Inc.
durée : 00:05:11 - La Revue de presse internationale - par : Catherine Duthu - Six jours après le passage de l'ouragan Melissa, l'un des plus puissants jamais recensés, les Caraïbes déplorent près de 60 morts. La Jamaïque, Cuba et Haïti continuent d'évaluer les dégâts matériels et les besoins de la population.
ADHD medication can be a controversial topic online. Is it safe? Does it change who you are? What does the science actually say?In this episode, Skye talks with Dr. Ryan Sultan, psychiatrist, researcher, and founder of Integrative Psychiatry in NYC, about what medication does in the brain and what decades of studies reveal about its effects. This is not medical advice - it's a clear, evidence-based conversation to help you understand your options.What we cover:How ADHD medication affects dopamine and focusThe difference between stimulant and non-stimulant medicationsWhy safety and addiction concerns often get misunderstoodHow to approach treatment decisions from an informed placeHow to know if your treatment plan needs adjustmentThe role of therapy, structure, and lifestyle alongside medicationDr. Ryan Sultan, MD is a double board-certified psychiatrist, Assistant Professor of Clinical Psychiatry at Columbia, and the Founder & Medical Director of Integrative Psychiatry in Chelsea, NYC, and Miami, FL. He leads NIH-funded research on ADHD and comorbidities and has published in JAMA, The Journal of Adolescent Health, and JAACAP. Clinically, he works with children and adults navigating conditions like anxiety, depression, and substance use.Medical Disclaimer:This episode is for educational purposes only and does not constitute medical advice.Skye Waterson is not a medical doctor and does not make treatment recommendations.Always consult a qualified healthcare professional before making any decisions about diagnosis, medication, or treatment for ADHD or any other condition.P.S. If you feel like the bottleneck in your business and life feels like chaos, click here to apply for a call with me. We'll discuss your struggles and explore systems to support you in growing without the overwhelm.
durée : 00:03:00 - Regarde le monde - On prend la direction des Caraïbes et de la Jamaïque, où le bilan de la catastrophe causée par l'ouragan Melissa est toujours provisoire. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.
durée : 00:04:46 - La BO du monde - De Shaggy à Sean Paul en passant par la Fondation Bob Marley, la communauté reggae et dancehall s'organise pour venir en aide aux sinistrés, quelques jours après le passage dévastateur de l'ouragan. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.
Après le passage dévastateur de l'ouragan Melissa dans les Caraïbes, en particulier dans l'ouest de la Jamaïque la semaine dernière, les agences des Nations Unies se mobilisent pour répondre aux besoins urgents des populations touchées.Alexis Masciarelli, chef de la communication pour l'Amérique latine et les Caraïbes au Programme alimentaire mondial (PAM), explique au micro de Charlotte Frantz, d'ONU Info, comment les équipes sur le terrain s'organisent et œuvrent à rétablir progressivement la sécurité alimentaire.(Interview: Alexis Masciarelli, chef de la communication pour l'Amérique latine et les Caraïbes au Programme alimentaire mondial de l'ONU (PAM) ; propos recueillis par Charlotte Frantz, d'ONU Info)
durée : 00:03:00 - Regarde le monde - On prend la direction des Caraïbes et de la Jamaïque, où le bilan de la catastrophe causée par l'ouragan Melissa est toujours provisoire. Vous aimez ce podcast ? Pour écouter tous les autres épisodes sans limite, rendez-vous sur Radio France.
Plongée au cœur de l'Amazonie avec Lucile Gimberg du service environnement de RFI en français et Lucia Muzell de la rédaction en brésilien. À l'approche de la COP 30 qui s'ouvrira dans quelques jours au Brésil, Anne Cantener reçoit les deux reporters qui reviennent de ce territoire immense. Elles signent toute une série de reportages disponibles sur le site internet de RFI en français et en brésilien. Les deux journalistes ont été marquées par la richesse et l'importance des savoirs traditionnels des communautés autochtones, en particulier en ce qui concerne la gestion de la forêt amazonienne. Il faut garder en tête que «c'est aussi et surtout une zone de rivières. L'eau fait vraiment partie du quotidien», souligne Lucile Gimberg. «Il y a également de nombreuses villes, comme Belém. 28 millions de personnes vivent en Amazonie», ajoute Lucia Muzell. Les premières traces d'habitat remontent à 12.000 ans et on peut s'inspirer des modes de vie des peuples originels pour protéger la nature, expliquent les reporters. «Par exemple, il faut rediversifier notre alimentation», explique Lucile Gimberg. «Ces peuples mangeaient 37 espèces de poissons !» Ces savoirs ancestraux sont d'ailleurs toujours utilisés aujourd'hui dans les communautés qui s'efforcent de les transmettre aux jeunes générations. Mais leur travail n'est pas toujours suffisamment reconnu et valorisé, notamment au niveau économique. Vidéo : Amazonie : et si l'avenir passait par la bioéconomie ? - RFI Amazônia: a equação delicada entre preservação e combate à pobreza - Planeta Verde COP30: Nas comunidades tradicionais amazônicas, clima mais quente já assusta e mobiliza adaptação - Planeta Verde Melissa : deuil national en Haïti Le Nouvelliste parle d'une trentaine de morts mais là encore, les chiffres devraient augmenter. Trois jours de deuil national ont été décrétés, à partir de ce lundi (3 novembre 2025), nous apprend Gazette Haïti. «Durant cette période, le drapeau national sera mis en berne sur tout le territoire, les discothèques et établissements assimilés resteront fermés, et les médias seront invités à adapter leur programmation avec de la musique et des émissions de circonstance», explique le journal. Six départements du pays restent en état d'urgence : le Sud, le Sud-Est, la Grand-Anse, les Nippes, l'Ouest et le Nord-Ouest, et ce pour une durée, de trois mois. À écouter aussiHaïti : à Petit Goâve, les habitants encore sous le choc après le passage de Melissa Les États-Unis débloquent trois millions de dollars pour Cuba Cet argent destiné en priorité aux habitants des régions orientales de l'île, les plus touchées par Melissa, sera distribué par l'Église catholique, relève 14 y Medio. Ce choix de l'Église catholique, «une institution avec une présence territoriale, crédible et bien vue par la population», précise le journal, met le gouvernement cubain «dans une situation difficile». Ce qui explique l'absence de réactions officielles des autorités face à cette offre de bons services. À lire aussiL'ouragan Melissa a touché Cuba mais perd de la puissance, rétrogradé en catégorie 3 Une majorité d'Américains estiment que Donald Trump va trop loin Selon un sondage effectué par Ipsos pour le Washington Post et ABC, près de deux-tiers des personnes interrogées jugent que le président outrepasse ses pouvoirs. Près de 60% des Américains ont une opinion défavorable de Donald Trump. Un taux d'insatisfaction jamais atteint depuis janvier 2021 et l'attaque du Capitole, fait remarquer le Washington Post. Principales raisons de ce mécontentement : les tarifs douaniers, et l'économie en général, et comment Donald Trump gère le gouvernement fédéral. En revanche, sur les questions d'immigration et de diversité, la société américaine semble divisée. La moitié des personnes sondées juge que Donald Trump va trop loin et l'autre moitié estime que ce qu'il fait est bien ou qu'il ne va pas assez loin. Dernier enseignement intéressant de ce sondage : les démocrates ne bénéficient pas de ce mécontentement. Près de 7 Américains sur 10 estiment que le parti est déconnecté de leurs vies. C'est 6 sur 10 pour les Républicains. Ceux qui désapprouvent l'action de Donald Trump, ne sont pas prêts pour autant à voter démocrates, souligne le Washington Post. À lire aussiÉtats-Unis: Donald Trump assume les méthodes brutales des opérations anti-immigration Nicolas Maduro renforce la censure Selon Tal Cual, le mois dernier, deux personnes ont écopé de 10 et 15 de prison. Elles ont été reconnues coupables de «délit de haine» lors de procès expéditifs, rapporte le journal en ligne. La première, âgée de 44 ans, avait critiqué le gouvernement lors d'une discussion privée sur WhatsApp ; la seconde âgée de 22 ans est accusée d'avoir posté sur TikTok une vidéo dans lequel elle disait du mal des autorités. Ces deux condamnations sont les dernières d'une longue série de personnes condamnées à de lourdes peines de prison pour avoir fait des remarques négatives sur le gouvernement dans un cadre privé, raconte Tal Cual qui fait le lien avec une décision de Nicolas Maduro. Afin d'encourager la délation, le 20 octobre 2025, il a demandé à ce que soit réactivée une fonction de l'appli VenApp afin de pouvoir signaler 24h/24 «tout ce que l'on voit, tout ce que l'on entend». À l'origine, VenApp, c'est un réseau social créé pour faire remonter les problèmes du quotidien, comme lorsqu'un service public ne fonctionne pas, explique Tal Cual. Aujourd'hui, on y trouve des onglets «terrorisme» ou bien «attaque de drones», précise le journal. Tout cela contribue à «créer un climat de silence et de terreur», analyse Martha Tineo, avocate et coordinatrice de l'ONG ONG Justicia, Encuentro y Perdón. Un «silence collectif» pour que la vérité disparaisse. Le journal de la 1ère Après le passage de Melissa, des milliers de Jamaïcains ont tout perdu. À lire aussiOuragan Melissa: le personnel médical de la Jamaïque mobilisé malgré les nombreux dégâts
Editor's Summary by Linda Brubaker, MD, Preeti Malani, MD, MSJ, Deputy Editors and Christopher W. Seymour, MD, MSc, Associate Editor of the Journal of the American Medical Association, for articles published from October 25-31, 2025.
C'est en Haïti que les vents, les pluies ou encore les inondations provoquées par le passage de l'ouragan Melissa ont été les plus meurtriers. Selon un bilan de la protection civile haïtienne, au moins 30 personnes sont mortes et 20 sont toujours portées disparues. À Petit Goâve, ville la plus endeuillée par le passage de l'ouragan, Gauda Estiverne a vu trois de ses quatre enfants disparaître dans les flots de la rivière Ladigue sortie de son lit. Yannick Jean Pierre, elle, a eu plus de chance. «J'ai failli mourir. L'eau a failli m'emporter. Regardez, ma maison est détruite. Je ne sais pas où je vais dormir», témoigne-t-elle. L'écrivaine haïtienne Yanick Lahens remporte le prix du roman de l'Académie française «Que le nom de Melissa soit banni», écrit Frantz Duval dans le journal Le Nouvelliste, et «que celui de Yanick rayonne». L'écrivaine, qui vit en Haïti, a été récompensée pour son roman Les passagères de la nuit. «Depuis plus d'un siècle, l'Académie française récompense des auteurs haïtiens pour la qualité de leurs œuvres», rappelle Frantz Duval. «Quelle joie, quelle fierté !», renchérit Gazette Haïti. Car dans un «pays en crise», et «malgré les blessures», ce prix rappelle «qu'Haïti demeure une terre de création et de génie, capable d'offrir au monde des voix puissantes, des écritures de lumière.» Plongée dans un musée sous-marin en Colombie Au large de l'Isla Fuerte, sur la côte caraïbe, des initiatives tentent de donner un second souffle aux coraux, garants de la vie marine mais qui sont gravement menacés aujourd'hui par le dérèglement climatique et par le tourisme de masse. Parmi elles, le Muszif, un musée entièrement immergé dans des eaux cristallines, où l'art devient refuge pour la vie marine et qu'a visité la correspondance de RFI en Colombie, Camille Bouju. Dans le journal d'Outre-mer La 1ère Les Antilles françaises et leurs forces armées viennent au secours de la Jamaïque, meurtrie par l'ouragan Melissa.
Elinzanetant, sold under the brand name Lynkuet, receivedapproval from the U.S. Food and Drug Administration (FDA) on October 24, 2025, for the treatment of moderate to severe hot flashes due to menopause. How is this different than Fezolinetant, which was approved in 2023? Listen in for details. 1. Menegaz de Almeida, Artur MS; Oliveira, Paloma MS; Lopes, Lucca MD; Leite, Marianna MS; Morbach, Victória MS; Alves Kelly, Francinny MD; Barros, Ítalo MS; Aquino de Moraes, Francisco Cezar MS; Prevedello, Alexandra MD. Fezolinetant and Elinzanetant Therapy for Menopausal Women Experiencing Vasomotor Symptoms: A Systematic Review and Meta-analysis. Obstetrics & Gynecology 145(3):p 253-261, March 2025. | DOI: 10.1097/AOG.00000000000058122. Pinkerton JV, Simon JA, Joffe H, Maki PM, NappiRE, Panay N, Soares CN, Thurston RC, Caetano C, Haberland C, Haseli Mashhadi N, Krahn U, Mellinger U, Parke S, Seitz C, Zuurman L. Elinzanetant for the Treatment of Vasomotor Symptoms Associated With Menopause: OASIS 1 and 2 Randomized Clinical Trials. JAMA. 2024 Aug 22;332(16):1343–54. doi: 10.1001/jama.2024.14618. Epub ahead of print. PMID: 39172446; PMCID: PMC11342219.3. Cardoso F, Parke S, Brennan DJ, Briggs P,Donders G, Panay N, Haseli-Mashhadi N, Block M, Caetano C, Francuski M, Haberland C, Laapas K, Seitz C, Zuurman L. Elinzanetant for Vasomotor Symptomsfrom Endocrine Therapy for Breast Cancer. N Engl J Med. 2025 Aug 21;393(8):753-763. doi: 10.1056/NEJMoa2415566. Epub 2025 Jun 2. PMID: 40454634.STRONG COFFEE PROMO: 20% Off Strong CoffeeCompany https://strongcoffeecompany.com/discount/CHAPANOSPINOBG
Le Journal en français facile du mercredi 29 octobre 2025, 17 h 00 à Paris. Retrouvez votre épisode avec la transcription synchronisée et des exercices pédagogiques pour progresser en français : http://rfi.my/C8i6.A
Di vê bûletene de: Civakên li Jamaîka piştî bahoza Melissa li ser timsehan hişyarî bo wan hat dayin... Danûstandin li ser reforma qanûnên jîngehê yên Australya berdewam dikin... Û di futbolê de, Socceroos dê di lîstikên ku ji bo meha bê hatine plankirin bi Venezêla û Kolombiya re bilîzin. Ew nûçeyana û nûçeyên din di bûlentenê de hene.
durée : 00:13:03 - Journal de 7 h - L'île caribéenne a fait face au pire ouragan de son histoire dans la soirée du mardi 28 octobre. Face à un paysage dévasté, la population découvre tout juste l'ampleur des dégâts.
Dans cette édition :L'ouragan Mélissa s'abat sur Cuba avec des vents atteignant 195 km/h, entraînant la déclaration de l'état d'alerte dans six provinces de l'Est du pays.Après avoir durement frappé la Jamaïque, l'ouragan a été rétrogradé en catégorie 3 et l'état de catastrophe naturelle a été déclaré, avec des dommages importants constatés notamment dans certains hôpitaux.En France, les députés ont voté pour doubler le taux d'imposition des géants du numérique comme Apple, Amazon, Facebook et Google, ainsi qu'une taxe massive sur leurs bénéfices, pour un gain espéré de 26 milliards d'euros.Le gouvernement était opposé à ces mesures, craignant des représailles de l'administration Trump, tandis que Bruno Retailleau, de la droite, juge le projet de budget "invotable".Le tribunal administratif de Paris doit décider si les députés de La France Insoumise seront autorisés à rendre visite à l'ancien président Nicolas Sarkozy en prison.Aux États-Unis, le président Donald Trump poursuit sa tournée en Asie, avec des contrats à la clé pour des entreprises américaines comme Amazon qui annonce un investissement de 5 milliards de dollars en Corée du Sud.Le numéro 1 mondial de tennis Carlos Alcaraz a été éliminé dès le deuxième tour du Masters 1000 de Paris.Notre équipe a utilisé un outil d'Intelligence artificielle via les technologies d'Audiomeans© pour accompagner la création de ce contenu écrit.Hébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.
Professeur de Sciences politiques à l'Université américaine de Paris, Philip Golub analyse pour RFI la politique étrangère de Donald Trump, qui poursuit cette semaine sa tournée en Asie. «America first», l'expression est née dans les années 1920 aux États-Unis, dans la bouche de ceux qui étaient en désaccord avec les engagements internationaux du président de l'époque, puis remise au goût du jour par Donald Trump près d'un siècle après. Il la martèle depuis son retour à la Maison Blanche. Pourtant, Donald Trump est présent sur un maximum de fronts ces derniers mois. Alors comment qualifier la politique étrangère de Donald Trump ? «Les États-Unis sont structurellement une puissance globalisée, nuance Philip Golub. Donald Trump n'est pas un isolationniste, mais un unilatéraliste, qui veut imposer sa volonté dans différents théâtres du monde, selon ce qu'il estime être l'intérêt national des États-Unis, poursuit celui qui enseigne à l'Université américaine de Paris (AUP). Ce qui correspond d'assez près à son intérêt personnel». Il va plus loin : «La politique internationale de Donald Trump est dirigée par son ego». Après la Jamaïque, l'ouragan Melissa touche Cuba et fait au moins 10 morts en Haïti Le jour d'après en Jamaïque. L'ouragan Melissa a traversé l'île des Caraïbes, mardi 28 octobre 2025, laissant de lourds dégâts sur son passage. Un «Désastre !» pour The Jamaica Observer. En Une du journal, s'affiche un amas de tôles et de poutres en partie immergées dans une eau boueuse. The Gleaner, pour sa part, multiplie les adjectifs choc : «Défiguré(e)», écrit le journal en majuscules, à sa Une ce mercredi 29 octobre 2025. «Ravagé(e)», lit-on aussi en titre d'un article sur son site. Le quotidien décrit les arbres arrachés, les lignes téléphoniques à terre. Melissa a atteint, mercredi 29 octobre 2025, le sud-est de Cuba. Rétrogradé en catégorie 3 (sur 5), mais avec des vents qui peuvent encore souffler à près de 200 km/h. L'ouragan a déjà provoqué «d'importants dégâts», assure le président cubain Miguel Diaz Canel. Plus de 700 000 personnes ont été évacuées. Haïti, pour sa part, n'a pas été touchée directement par l'œil de l'ouragan, mais toute la moitié sud du pays est en alerte rouge, y compris la capitale, Port-au-Prince. Face à cela, les autorités haïtiennes ont déclaré, ce mercredi chômé, explique Gazette Haïti. Objectif : «permettre à la population de se préparer et de réduire les risques liés au passage de l'ouragan», poursuit le site d'information. À lire aussiLa Jamaïque, «zone sinistrée» après le passage de l'ouragan Melissa Brésil : L'opération de police la plus meurtrière de l'histoire de Rio À Rio de Janeiro, une gigantesque opération de police ordonnée par le gouverneur Claudio Castro s'est soldée, mardi 28 octobre 2025, par au moins 132 morts. Ce mercredi matin, des dizaines cadavres ont été alignés dans la rue par les habitants eux-mêmes, dans l'un des quartiers visés par l'opération, écrit Folha de Sao Paulo sur son site. Les familles cherchent à identifier les victimes. D'après les autorités, les policiers visaient des membres du principal groupe criminel de la ville, le Comando Vermelho. À lire aussiScène de guerre à Rio de Janeiro: des dizaines de morts dans une opération anti-drogue
On this episode of KeyLIME+, Adam speaks with Charlotte van Sassen about the subtle ways that knowledge of patient outcomes can influence how supervisors assess clinical reasoning. Their conversation uncovers the impact of outcome bias on feedback and evaluation in medical education, exploring the challenges this presents for fairness and learning. They also discuss strategies to recognize and address these biases, aiming to improve how we support trainee development in complex clinical environments. Length of episode : 30:52 Resources to check out: https://pubmed.ncbi.nlm.nih.gov/40479526/ van Sassen C, Mamede S, van den Broek W, Bindels P, Zwaan L. Does Knowledge of Clinical Case Outcome Influence Supervisor Evaluation of Resident Clinical Reasoning? Acad Med. 2025 Jun 6 Zwaan L, Monteiro S, Sherbino J, et al Is bias in the eye of the beholder? A vignette study to assess recognition of cognitive biases in clinical case workupsBMJ Quality & Safety 2017;26:104-110. https://qualitysafety.bmj.com/content/26/2/104.abstract Caplan RA, Posner KL, Cheney FW. Effect of Outcome on Physician Judgments of Appropriateness of Care. JAMA. 1991;265(15):1957–1960. doi:10.1001/jama https://jamanetwork.com/journals/jama/article-abstract/385633 Contact us: keylime@royalcollege.ca Follow: Dr. Adam Szulewski https://x.com/Adam_Szulewski
Accompagné de vents violents et de risques importants d'inondations, l'ouragan Melissa de catégorie 5 a frappé mardi la Jamaïque. Les experts prévoient que cet ouragan « catastrophique » va avoir un impact massif sur des centaines de milliers de personnes. Au micro de Charlotte Frantz, Eric Falt, Représentant de l'UNESCO en Jamaïque, décrit à ONU Info la situation sur place.
Today we're thrilled to get to know Travis Zack, Chief Medical Officer of OpenEvidence. OpenEvidence is the world's leading medical information platform and the fastest growing applications for physicians in history. Over 40% of US clinicians leverage OpenEvidence for evidence based practice support that is directly embedded into their workflows.Through an array of strategic content partnerships (including the American Medical Association, The New England Journal of Medicine, The Journal of the American Medical Association, and all eleven JAMA specialty journals—such as JAMA Oncology and JAMA Neurology) OpenEvidence gives clinicians the power to search once, skip the scavenger hunt, and surface the science in seconds. Most recently, OpenEvidence has raised $200M in its Series C from Top Investors like Sequoia, GV Thrive, Kleiner Perkins and others!In this episode, we discuss how OpenEvidence is transforming access to medical evidence, the company's rapid growth and adoption by clinicians, its business model and journal partnerships, and the future roadmap for AI-powered clinical decision support.
Editor's Summary by Linda Brubaker, MD, and Preeti Malani, MD, MSJ, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from October 18-24, 2025.
A new JAMA study reveals that since Idaho's near-total abortion ban took effect, the state has lost 35% of its obstetricians, intensifying already limited access to maternity care - especially in rural communities.
Autism isn't new, but our understanding of it has changed dramatically. It's now recognized as a broad neurodevelopmental spectrum that shapes how millions of people perceive, process, and interact with the world. In this episode, we explore what autism is AND isn't, from its earliest signs in infancy to its deep genetic roots, and why misinformation about it continues to spread. We speak with three remarkable experts leading the field in early detection, genetics, and public education: DR. AMI KLIN, PhD, Director of the Marcus Autism Center at Emory University and a pioneer in early autism research, whose work shows autism can be identified in babies as young as two months old. DR. JOSEPH BUXBAUM, PhD, Director of the Seaver Autism Center at Mount Sinai and a global leader in autism genetics, uncovering hundreds of genes linked to the condition. DR. ANDREA LOVE, immunologist, microbiologist, and founder of ImmunoLogic, known for her clear, evidence-based communication about vaccines, immunity, and autism myths. Together, we discuss: • What autism really is, and how the definitions have evolved • How it develops in infancy (and why early diagnosis can be so critical) • The powerful genetic evidence behind autism • The persistence of vaccine myths, and how misinformation spreads • How technology like eye-tracking can detect autism early • The rise of “profound autism” and what it means for families • The future of genetics-based treatments and therapy Whether you're autistic yourself, a parent navigating a new diagnosis, or simply seeking understanding, we're thrilled to share this extensive, in-depth episode with you. This is... Your Brain On Autism. SUPPORTED BY: the 2026 NEURO World Retreat. A 5-day journey through science, nature, and community, on the California coastline: https://www.neuroworldretreat.com/ ‘Your Brain On' is hosted by neurologists, scientists, and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Autism' • SEASON 6 • EPISODE 1 LINKS Dr. Ami Klin at Emory University: https://ctsn.emory.edu/faculty/klin-ami.html Dr. Ami Klin at Marcus Autism Center: https://www.marcus.org/about-marcus-autism-center/meet-our-leadership/ami-klin Dr. Joseph Buxbaum at Mount Sinai: https://profiles.icahn.mssm.edu/joseph-d-buxbaum Dr. Andrea Love's website: https://www.immunologic.org/ Dr. Andrea Love on Instagram: https://www.instagram.com/dr.andrealove REFERENCES Autism Spectrum Disorder: A Review. JAMA, 2023. https://jamanetwork.com/journals/jama/article-abstract/2800182 Is There a Bias Towards Males in the Diagnosis of Autism? A Systematic Review and Meta-Analysis. https://link.springer.com/article/10.1007/s11065-023-09630-2 Acetaminophen Use During Pregnancy and Children's Risk of Autism, ADHD, and Intellectual Disability. https://pubmed.ncbi.nlm.nih.gov/38592388/ Eye-Tracking–Based Measurement of Social Visual Engagement Compared With Expert Clinical Diagnosis of Autism. https://jamanetwork.com/journals/jama/fullarticle/2808996 Rare coding variation provides insight into the genetic architecture and phenotypic context of autism. https://www.nature.com/articles/s41588-022-01104-0 Rare coding variation illuminates the allelic architecture, risk genes, cellular expression patterns, and phenotypic context of autism. https://www.medrxiv.org/content/10.1101/2021.12.20.21267194v1 Andrew Wakefield and the fabricated history of the alleged vaccine-autism link. https://geneticliteracyproject.org/2024/04/29/andrew-wakefield-and-the-fabricated-history-of-the-alleged-vaccine-autism-link/ VACCINES & AUTISM 1. Major Cohort Studies Hviid et al., 2019 – Annals of Internal Medicine A nationwide study of 657,461 Danish children found no increased risk of autism in vaccinated children compared to unvaccinated peers — even among those with risk factors such as a sibling with autism. Ann Intern Med. 2019;170(8):513–520 Madsen et al., 2002 – New England Journal of Medicine In 537,303 Danish children, researchers found no difference in autism rates between vaccinated and unvaccinated groups, and no relationship with age, timing, or date of vaccination. NEJM. 2002;347:1477–1482 Jain et al., 2015 – Journal of the American Medical Association (JAMA) A U.S. cohort of 95,727 children — including those with siblings with autism — showed no link between MMR vaccination and autism risk, even in genetically predisposed children. JAMA. 2015;313(15):1534–1540 Madsen et al., 2003 – JAMA A study of 467,450 Danish children found no relationship between thimerosal-containing vaccines and autism. JAMA. 2003;290(13):1763–1766 DeStefano et al., 2022 – Vaccine A retrospective cohort of over 500,000 U.S. children with ASD found no increase in adverse events or worsening of autism-related symptoms following vaccination. Vaccine. 2022;40(16):2391–2398 2. Population-Level Epidemiologic Evidence Taylor et al., 1999 – The Lancet One of the earliest large epidemiological studies found autism prevalence was the same in vaccinated and unvaccinated children, and the age of onset was unrelated to the timing of MMR vaccination. Read: Lancet. 1999;353(9169):2026–2029 Institute of Medicine (U.S.) Immunization Safety Review, 2011 A global review of studies from the U.S., Denmark, Sweden, and the U.K. concluded there is no causal relationship between vaccination status and autism, and no plausible biological mechanism linking vaccines (including thimerosal) to ASD. Read: National Academies Press / PubMed 20669467 3. Systematic Reviews and Meta-Analyses Taylor et al., 2014 – Vaccine A comprehensive meta-analysis of 10 studies including over 1.2 million children found no association between vaccination and autism or ASD. Vaccine. 2014;32(29):3623–3629 Maglione et al., 2014 – Pediatrics Review of 67 high-quality studies covering the full U.S. immunization schedule concluded that vaccines are safe, adverse events are rare, and there is no link to autism, type 1 diabetes, or other chronic conditions. Pediatrics. 2014;134(2):325–337 Parker et al., 2004 – Pediatrics Systematic review of 10 primary studies examining thimerosal exposure found no relationship between vaccines and ASD. Authors noted that studies showing an association were methodologically flawed or biased, while robust studies consistently showed safety. Pediatrics. 2004;113(6):1904–1910 Offit & Hackett, 2003 – Clinical Infectious Diseases Review of immunology and epidemiology concluded that claims that vaccines “overwhelm” or “damage” the immune system are not biologically plausible based on how the immune system actually functions. Clin Infect Dis. 2003;46(9):1450–1456
Sasha K. Shillcutt, MD, MS, FASE is a tenured and endowed Professor and the Vice Chair of Strategy in the Department of Anesthesiology at the University of Nebraska Medical Center. She is a double-boarded cardiac anesthesiologist and is also CEO & Founder of Brave Enough, a community of thousands of women in healthcare where she teaches women how to advance through courses, coaching, and events. She leads conferences and retreats for professional women and is a certified coach for women leaders. Sasha is a well-published researcher in anesthesiology and gender equity, best-selling author, and international speaker. She speaks frequently to executives and leaders on the topics of professional resilience and wellbeing. Her TEDx talk titled Resilience: The Art of Failing Forward has been viewed by thousands of people. Her writing has been published in both the New England Journal of Medicine and JAMA. Her first book, Between Grit and Grace: How to be Feminine and Formidable, has sold thousands of copies and her second book, Brave Boundaries, is an international best seller. Her podcast, The Brave Enough Show, has over 315K downloads & she has coached hundreds of women leaders to thrive. Some of the topics we discussed were: Setting boundaries at work, in business, or entrepreneurshipSetting and keeping boundaries that serve you Common mistakes people make when setting up boundaries and how to avoid themHow to navigate situations where people are unhappy with the boundaries you setRecommendations for people on their journey of learning better boundariesHow to approach situations where you feel someone is setting an unreasonable boundaryBoundaries and time management And more!Learn more about me or schedule a FREE coaching call:https://www.joyfulsuccessliving.com/ Join the Voices of Women Physicians Facebook Group:https://www.facebook.com/groups/190596326343825/ Connect with Dr. Shilcutt: WEBSITE INSTAGRAM FACEBOOK TWITTER LINKEDIN
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