Genus of Gram-positive bacteria, which includes several significant human pathogens
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Dr. Don and Professor Ben talk about the risks from eating deviled eggs made from home-canned, split open hard-boiled eggs. Dr. Don - risky ☣️ Professor Ben - risky ☣️ Canning Rebels | Hard boiled egg experiment | Facebook Text of “GREEN EGGS AND HAM” (by Doctor Seuss) Green Eggs and Ham - Google Books Food Safety Talk 319: I'm Feeling Botchy Today — Food Safety Talk Pickled Eggs - National Center for Home Food Preservation Why do Eggs Turn Green When Cooked? | Incredible Egg Full article: Investigation of a type C/D botulism outbreak in free-range laying hens in France Challenge studies with Listeria monocytogenes and proteolytic Clostridium botulinum in hard-boiled eggs packaged under modified atmospheres - ScienceDirect Pressure Canning Whole Eggs for the pantry! *NOT a G0v+ approved method #storingeggs #preservingeggs - YouTube Foodborne Botulism From Eating Home-Pickled Eggs — Illinois, 1997 Freezing Eggs - National Center for Home Food Preservation
Dr. Don and Professor Ben revisit episode 759, and talk about the risks of eating from big open spoiled jar of canned peaches at room temperature. Dr. Don - risky ☣️ Professor Ben - risky ☣️ 759. Big Open Jar of Canned Peaches at Room Temperature — Risky or Not? Further Studies on Development of Clostridium Botulinum in Refrigerated Foods 1 - Tanner - 1940 - Journal of Food Science - Wiley Online Library Further Studies on Development of Clostridium botulinum in Refrigerated Foods - abstract Growth and Toxin Production by Clostridium botulinum in Sauteed Onions - ScienceDirect Journal of Food Science - Wikipedia
Support your health journey with our private practice! Explore comprehensive lab testing, functional assessments, and expert guidance for your wellness journey. Find exclusive offers for podcast listeners at nutritionwithjudy.com/podcast. _____Dr. Neil and I dive into the complexity of the gut microbiome, challenging the notion that a single probiotic strain can fix everything. We explore how diversity—not one 'superbug'—may be the real key to gut health. We also unpack how fecal transplants work, why antibiotics often do more harm than good, and if fermented foods are necessary or ideal.Dr. Neil Stollman is a practicing gastroenterologist based in Oakland, California, and serves as voluntary faculty at UCSF. A pioneer in the field of fecal microbiota transplantation (FMT), he has been involved in gut microbiome research and treatment for over two decades. Known for his work with Clostridium difficile infection (CDI) and broader gut health issues, Dr. Stollman brings a balanced and often humorous perspective to microbiome science.We discuss the following:All about Dr. Neil StollmanThe importance of gut healthAll about AkkermansiaGlyphosate and other antimicrobial foodsFMT (Fecal Microbiota Transplantation)Getting sick from C. diff (Clostridioides difficile)Strengthening the MicrobiomeDo we need FermentsThoughts on giving antibiotics to people with C. diffSymptoms of H. pyloriThoughts on long-term PPI useWhy gut doctors prescribe PPIsThoughts on colon testsWhere to find Dr. Neil Stollman_____EPISODE RESOURCESWebsiteTwitterThe Sonnenburgs Fermented Food StudyOpenBiome (Stool Bank)NwJ Complete Wellness PanelComplete GI Map Stool Test_____WEEKLY NEWSLETTER
Baisser l'abattant des toilettes avant de tirer la chasse est un geste simple, mais crucial pour des raisons d'hygiène, souvent sous-estimées. Ce réflexe permet de limiter la dispersion de microgouttelettes contaminées, un phénomène bien documenté par la science.Le phénomène de l'« aérosol fécal »Lorsque l'on tire la chasse d'eau, surtout dans des toilettes sans couvercle, un nuage invisible d'aérosols est projeté dans l'air. Ces microgouttelettes peuvent contenir des bactéries, des virus, et d'autres agents pathogènes présents dans les selles et l'urine. Une étude clé publiée en 2020 dans la revue Physics of Fluids a utilisé des simulations en 3D pour visualiser ce phénomène. Les chercheurs ont observé qu'un jet puissant de la chasse propulsait des gouttelettes jusqu'à un mètre au-dessus de la cuvette, en moins de six secondes. Ces particules peuvent ensuite rester en suspension dans l'air pendant plusieurs minutes, voire se déposer sur les surfaces environnantes.Contamination des surfacesLes toilettes sont souvent situées dans des espaces clos, où les surfaces proches — poignée de porte, lavabo, brosse WC, serviettes, brosse à dents — sont particulièrement vulnérables à cette contamination. Une étude publiée en 2005 dans le Journal of Hospital Infection a montré que le tirage de la chasse, sans abattant fermé, provoquait une dispersion bactérienne significative sur les surfaces jusqu'à plusieurs dizaines de centimètres autour des toilettes.Ces dépôts peuvent abriter des bactéries comme E. coli, Salmonella, Clostridium difficile, ou encore des virus gastro-intestinaux. Or, certaines de ces bactéries peuvent survivre plusieurs heures, voire plusieurs jours, sur les surfaces inertes. Cela augmente le risque de transmission indirecte par contact avec les mains.Un geste d'hygiène simple et efficaceFermer l'abattant agit comme une barrière mécanique. Même si cela ne bloque pas 100 % des aérosols, cela réduit drastiquement leur dispersion. Selon des recherches menées à l'Université de Leeds (UK), fermer le couvercle avant de tirer la chasse permet de diminuer la libération de bactéries dans l'air de plus de 50 %. Cela a d'autant plus d'importance dans les lieux partagés, comme les toilettes publiques, familiales ou professionnelles.En conclusionTirer la chasse sans fermer l'abattant revient à pulvériser dans l'air un mélange de microgouttelettes potentiellement infectieuses. En adoptant le réflexe de baisser le couvercle, on réduit ce risque de manière simple, rapide et efficace. Un petit geste d'hygiène… pour un grand bénéfice sanitaire. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Dr. Don and Professor Ben talk about the risks from eating peaches from big open jar of canned peaches kept at room temperature. Dr. Don - not risky
In this emotional episode of The Miracle Files, sisters Emily Jones and Holly Worthington share the incredible true story of Sadie Harris, a young mother who faced a 100% fatal bacterial infection, Clostridium sordellii, just days after giving birth. What started as a joyful new chapter with her newborn son, James, quickly turned into a desperate fight for survival. With her father, an ER doctor, cracking the medical mystery and a series of divine interventions, this uplifting tale of faith, family, and God's grace will leave you in tears and full of hope. And while you might think you know how this ends, you don't! You will be amazed!
On episode #77 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 3/13/25 – 3/26/25. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Food is medicine for human immunodeficiency virus: improved health and hospitalizations in the changing health through food support (chefs-hiv) pragmatic randomized trial (JID) The epidemiology and burden of human parainfluenza virus hospitalizations in u.s. children (Journal of the Pediatric Infectious Diseases Society) Bacterial Epidemiology and outcomes of bloodstream infections in patients in a burns intensive care unit: an eight-year retrospective study(OFID) Prophylactic vancomycin in the primary prevention of clostridium difficile in allogeneic stem cell transplant(Transplant Infectious Disease) Incidence of scrub typhus in rural south India (NEJM) Antibiotic treatment for 7 versus 14 days in patients with bloodstream infections(NEJM) Blood Culture–Negative Endocarditis(Journal of the American Heart Association) Brucella suis Infection in Cardiac Implantable Device of Man Exposed to Feral Swine Meat, Florida, USA (CDC Emerging Infectious Diseases) Hyperbilirubinemia at hospitalization predicts nosocomial infection in decompensated cirrhosis (Hepatology Communicatons) Fungal The Last of US Season 2 (YouTube) Fungal Infections in People Who Use Drugs (OFID) IDSA 2025 guideline update on the treatment of asymptomatic histoplasma pulmonary nodules (histoplasmomas) and mild or moderate acute pulmonary histoplasmosis in adults, children, and pregnant people(IDSA: Infectisous Disease Society of America) Changing trends in the sources and volumes of clinical cultures with Candida auris at a large health system, 2019-2023 (American Journal of Infection Control) Diagnostic test accuracy of the Fungitell serum (1→3)-β-D-glucan assay for the diagnosis of Pneumocystis jirovecii pneumonia: a systematic review and meta-analysis (CMI: Clinical Microbiology and Infection) Parasitic Impact of Strongyloides stercoralis Coinfection on Disease Severity and Treatment Outcomes in Pulmonary Tuberculosis (OFID) Hematology thin smears perform equally to parasitology thick and thin blood smears for the diagnosis of Plasmodium and Babesia infections in a low prevalence setting (Journal of Clinical Microbiology) Notes from the Field: Rhodesiense Human African Trypanosomiasis (Sleeping Sickness) in a Traveler Returning from Zimbabwe — United States, August 2024 (CDC: MMWR) Miscellaneous The history of phage therapy LANCET: Infectious Diseases) Silence=death redux: infectious diseases, public health, and the imperative to resist (CID) Silence = Death, 1990(David Wojnarowicz Foundation) SILENCE=DEATH (B200KLYN Museaum) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.
In a fascinating conversation with Professor Max Nieuwdorp of the Amsterdam Medical Centre, Dr James McIlroy explores groundbreaking ideas and research surrounding the microbiome, hormones, and their profound impact on metabolic diseases. This insightful dialogue uncovers the remarkable potential of faecal microbiota transplant (FMT) and emerging pharmaceutical strategies in tackling obesity, diabetes, and even cancer. Timestamps: 00:00 Introduction to Professor Max and the Podcast 02:04 Max's Journey into Microbiome Research 05:06 The Power of Fecal Microbiota Transplantation (FMT) 08:11 Microbiome's Role in Obesity and Metabolic Health 10:42 Challenges and Future Directions in Microbiome Research 14:47 Defining Obesity and Its Genetic Factors 18:39 FMT and Its Impact on Various Diseases 23:48 Optimal Diet for a Healthy Microbiome 31:07 The Power of Combining Probiotics 31:36 The GLP-1 Story: A Deep Dive 32:30 Mechanisms and Effects of GLP-1 Drugs 37:26 The Role of Microbiome in Weight Management 39:18 Selecting the Best Donor for FMT 42:27 Impact of Diet on Microbiome and Health 50:17 Future of Microbiome Research and Therapies 56:13 The Power of Hormones: Book Insights The Journey into Microbiome Research Professor Nieuwdorp's interest in the microbiome began serendipitously during his postdoctoral studies at UCSD. There, he encountered revolutionary ideas, particularly through the work of Jeffrey Gordon, which highlighted the significance of the microbiome long before it became widely acknowledged. An unforgettable early success with FMT on a patient with Clostridium difficile infection set the foundation for his enduring commitment to this field. Over the years, Nieuwdorp has been involved in pivotal studies, evolving his understanding of how microbiome therapies could be used in metabolic diseases and beyond. Understanding FMT and Its Role FMT has shown remarkable efficacy, especially in treating infections like Clostridium difficile. The discussion highlights an astounding 90% cure rate demonstrated in early trials, a feat Nieuwdorp describes as "seminal". Nonetheless, expanding this success to metabolic conditions such as obesity and autoimmune diseases remains a promising, yet ongoing, challenge. The Nexus Between Microbiome and Obesity While the connection between the microbiome and obesity remains a complex issue, Nieuwdorp emphasises how the microbiome's role in weight control is likely more significant over the long term—akin to directing an oil tanker—than as a quick fix. The conversation delves into why the body finds it easier to gain weight than to lose it, considering genetic predispositions and evolutionary pressures. This adaptability of the microbiome, combined with dietary habits, may significantly influence how our bodies metabolise and store energy. Revolutionary Treatments on the Horizon Emerging pharmacological treatments such as GLP-1 agonists are causing waves in medicine. These drugs, alongside the potential of next-generation probiotics, promise to reshape how obesity and associated conditions are treated. Intriguingly, research continues to suggest the microbiome might itself produce GLP-1, hinting at a future where therapies target these microbial mechanisms directly. The Path Forward: Microbiome as a Predictive Tool Professor Nieuwdorp envisions a future where microbiome profiling becomes a standard diagnostic and preventative tool. It has the potential to predict disease susceptibility, allowing for earlier and more personalised interventions. In parallel, the continued development of FMT and its derivatives may revolutionise treatments for a range of conditions, from cancer to metabolic disorders. The Educational Perspective: "The Power of Hormones" In addition to his pioneering research, Nieuwdorp shares insights in his book, The Power of Hormones, presenting a layperson's guide to understanding hormones across a lifespan. This book interweaves historical narratives with scientific discussion to elucidate how hormones and the microbiome intersect in influencing daily life. This extensive dialogue with Professor Nieuwdorp is a testament to the potential of microbiome science and the exciting horizon that awaits both researchers and patients. As innovations continue, integrating microbiome knowledge with traditional medical interventions could profoundly change how we understand and treat human health.
Probiotics may theoretically benefit children’s microbiome. Although they are generally safe, is there evidence to show that they result in improved gut health for children? We are joined by Dr. Natasha Nakra in this episode to discuss both probiotics and prebiotics, and get to the bottom of making sure that your child has a happy and healthy microbiome. We thank Dr. Natasha Nakra, Professor of Pediatric Infectious Diseases at UC Davis Children’s Hospital for joining us for this episode, although Drs. Dean and Lena take responsibility for any errors or misinformation. This episode written by Drs. Nakra, van der List and Blumberg. Additional resources: Healthy Children: Can probiotics help when my child has an infection and needs to take antibiotics? Healthy Children: Probiotics in Infant Formula IDSA: Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by SHEA/IDSA Photo courtesy of NIH Probiotics may theoretically benefit children’s microbiome. Although they are generally safe, is there evidence to show that they result in improved gut health for children? We are joined by Dr. Natasha Nakra in this episode to discuss both probiotics and prebiotics, and get to the bottom of making sure that your child has a happy and healthy microbiome. We thank Dr. Natasha Nakra, Professor of Pediatric Infectious Diseases at UC Davis Children’s Hospital for joining us for this episode, although Drs. Dean and Lena take responsibility for any errors or misinformation. This episode written by Drs. Nakra, van der List and Blumberg. Additional resources: Healthy Children: Can probiotics help when my child has an infection and needs to take antibiotics? Healthy Children: Probiotics in Infant Formula IDSA: Clinical Practice Guidelines for Clostridium diff
This podcast explores the role of probiotics in maintaining the health and productivity of dairy cows and calves. It highlights how specific probiotic strains enhance gut health, digestion, and immune function, leading to improved herd stability and fewer health challenges. Key points: Strain Selection Matters: Not all probiotics are equal—specific strains provide targeted benefits, making strain selection crucial for effective probiotic use. Probiotics and Digestive Health: Beneficial bacteria, such as Lactobacillus and Bacillus species, support digestion, absorption, barrier and immune functions. Probiotics in Calf Health: Research trials demonstrated that probiotics helped mitigate Clostridium perfringens challenges in calves, supporting normal performance and improving survival rates. Key time markers: 1:05: What is Novonesis?1:56: What does Novonesis do?2:55: What makes probiotics effective?4:34: Strain matters6:15: The benefits of effective probiotics11:19: What are our effective probiotics for dairy animals?16:31: Effective probiotics support the well-being of the animals in our care20:40: Effective probiotics for dairy cows This episode is sponsored by Chr. Hansen. Novonesis is a global biosolutions company with extensive expertise in bacteria culture science. As the product of two industry powerhouses — Chr. Hansen and Novozymes — Novonesis is poised to continue building on their more than 100-year history of bettering our world with biology. We're on a mission to leverage the power of microbiology with science to transform global production and consumption. A big piece of that starts on the farm, with your herds. Why? Because daily feeding of effective probiotics helps herds perform at peak efficiency.
Les aliments sous vide durent plus longtemps grâce à un processus qui limite les principales causes de dégradation des aliments : l'oxydation, la prolifération microbienne, et l'évaporation.L'oxygène et l'oxydationL'oxygène de l'air joue un rôle central dans la dégradation des aliments. En présence d'oxygène, les graisses s'oxydent, ce qui provoque un rancissement. Les vitamines, comme la vitamine C, peuvent également se décomposer, réduisant la qualité nutritionnelle des aliments. En retirant l'air d'un emballage sous vide, on réduit considérablement la quantité d'oxygène disponible, ce qui ralentit ces réactions chimiques.La prolifération microbienneLa majorité des micro-organismes responsables de la détérioration des aliments, tels que les bactéries et les moisissures, nécessitent de l'oxygène pour se développer. En créant un environnement pauvre en oxygène, le conditionnement sous vide inhibe leur croissance. Cela est particulièrement efficace pour les bactéries aérobies, mais il convient de noter que certaines bactéries anaérobies, comme Clostridium botulinum, peuvent encore se développer si les conditions de conservation (température, durée) ne sont pas respectées.La réduction de l'évaporationLes aliments contiennent de l'eau qui peut s'évaporer, entraînant un dessèchement ou une perte de texture. L'emballage sous vide empêche cette évaporation en maintenant une barrière étanche. Cela est particulièrement utile pour les produits sensibles comme les fruits, les légumes ou les viandes.Conservation des arômes et texturesEn l'absence d'oxygène et d'humidité, les arômes et les textures des aliments sont mieux préservés. Cela est particulièrement important pour les produits sensibles à l'air, comme le café ou les épices.Limites et précautionsBien que le sous-vide prolonge la durée de conservation, il ne rend pas les aliments éternels. Les produits doivent être stockés à des températures appropriées pour éviter la croissance de bactéries anaérobies. De plus, certains aliments très périssables, comme le poisson frais, nécessitent des conditions strictes pour prévenir tout risque sanitaire.En conclusion, le conditionnement sous vide agit comme une solution efficace en ralentissant les processus naturels de dégradation, offrant ainsi une conservation prolongée tout en préservant la qualité des aliments. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Dans l'épisode 55 de « Symptômes », le Dr William Berrebi raconte l'histoire d'une jeune femme de 29 ans, venue le consulter après trois années d'errance médicale. Elle lui raconte qu'elle souffre de diarrhées très importantes et incontrôlées, une dizaine de fois par jour. Le diagnostic révèle qu'elle est touchée par une bactérie appelée le Clostridium difficile. L'occasion dans ce bonus d'évoquer l'équilibre de notre microbiote et de son impact sur notre ventre, et notre santé en général.
We discuss the recognition and treatment of necrotizing fasciitis. Hosts: Aurnee Rahman, MD Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Necrotizing_Fasciitis.mp3 Download Leave a Comment Tags: Critical Care, General Surgery Show Notes Table of Contents 0:00 – Introduction 0:41 – Overview 1:10 – Types of Necrotizing Fasciitis 2:21 – Pathophysiology & Risk Factors 3:16 – Clinical Presentation 4:06 – Diagnosis 5:37 – Treatment 7:09 – Prognosis and Recovery 7:37 – Take Home points Introduction Necrotizing soft tissue infections can be easily missed in routine cases of soft tissue infection. High mortality and morbidity underscore the need for vigilance. Definition A rapidly progressive, life-threatening infection of the deep soft tissues. Involves fascia and subcutaneous fat, causing fulminant tissue destruction. High mortality often due to delayed recognition and treatment. Types of Necrotizing Fasciitis Type I (Polymicrobial) Involves aerobic and anaerobic organisms (e.g., Bacteroides, Clostridium, Peptostreptococcus). Common in immunocompromised patients or those with comorbid...
Rediffusion - Durant le mois de septembre, une quinzaine de personnes ont été hospitalisées après avoir contracté le botulisme, une maladie rare et grave. L'une des personnes est d'ailleurs décédée des suites de l'atteinte par la bactérie responsable, Clostridium... Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
In this episode, we review the high-yield topic of Clostridium tetani from the Microbiology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets
We share how you can prevent scours this calving season, but you have to act now! We have the latest news, market recaps, horse for sale, ranch channel listings and lots more on this all new episode of the Ranch It Up Radio Show. Be sure to subscribe on your favorite podcasting app or on the Ranch It Up Radio Show YouTube Channel. EPISODE 216 DETAILS Prevent Scours This Upcoming Calving Season Plus Cattle Industry News How To Prevent Calf Scours: Feed Farmatan Feed Farmatan To Prevent Scours This Calving Season Calving season is getting ready to start for many producers and for some others it is still a ways away yet. Regardless, we need to get a jump on scours and make sure each and every calf that hits the ground has the best chance of survival. A simple solution… FARMATAN from Imogene Ingredients. WHAT CAUSES SCOURS IN BEEF CATTLE/CALVES Clostridia-Enterotoxemia The most common form of Clostridium in cattle is caused by Clostridia perfringens. The gram-positive bacteria are a challenge due to its ability to form spores and lay dormant for long-periods of time. The bacteria reproduce by releasing spores into its environment (soil, feed, manure). The spores can even lay dormant in the animal's intestine until opportunity presents itself. Infection takes place either through ingestion of spores or through an open wound. The most severe cases happen within the first month of a calf's life, and can result in sudden death. Clinical Signs Diarrhea - Bloody, Mucus Present, Bubbly Dehydrated Bloat Blindness Prevention/Treatment: Prevention can be difficult due to the Clostridia spores being extremely durable and present almost everywhere. Complete cleanout and disinfection between calves is helpful, but not always effective. A good vaccination program will reduce clinical disease. The best method is to develop good gut health and the immune system of the calf. Farmatan has been shown to strengthen the intestinal wall, helping to prevent infection from taking hold. Coccidiosis Cattle are host to numerous species of Coccidia, a single-celled protozoal parasite. Infection and clinical symptoms can happen any time during a calf's life, with the most severe reaction usually occurring between 3-6 weeks of age. The life-cycle of coccidia requires time to infect the intestine causing destruction of the mucosal and epithelial lining. The oocytes mature outside the host in warm, moist environments before being consumed, causing infection of a new host. Clinical Signs Diarrhea - Watery, Bloody Depression Weight Loss Prevention/Treatment: Prevention of Coccidiosis is possible by keeping young calves separate from older animals, providing clean water and feed, and dry conditions. Isolation of infected animals is key to preventing transmission. Keeping the pen dry is the most important step a farmer/rancher can take in preventing Coccidiosis. Treatment can have a good impact on reducing secondary disease, and speeding up recovery time. Farmatan has been shown to disrupt the reproductive cycle of Coccidia; and may help strengthen the intestinal wall to prevent infection, in both the cow and calf. Coronavirus Bovine Coronavirus is a ubiquitous, envelope-viral disease, causing respiratory and enteric infection. There are many serotypes for this virus, making it difficult to test for, and create a vaccine. Coronavirus can present as either diarrhea and/or respiratory illness; transmitted through nasal discharge and/or feces. Animal reservoirs continue to spread the disease, and make eradication almost impossible. Clinical disease will likely occur between days 10-14, and present for up to 4 days. Clinical Signs Diarrhea - Watery Nasal Discharge Coughing Prevention/Treatment: Prevention is difficult due to wild animals transmitting the disease. Keeping wild animals out of animal enclosures is essential. Isolation of infected animals is critical to preventing the spread of Coronavirus. Adequate colostrum intake, along with a good vaccination program will help prevent clinical disease. Learn more about the positive effects of Farmtan's active ingredient on Coronavirus HERE. Cryptosporidium Cryptosporidium Parvum is a single-celled parasite responsible for causing infection in young calves. The infection takes place within the first four weeks of a calves' life, afterwards immunity has developed within the calf. The parasite is either passed from the cow or spread through infected water sources. Clinical Signs Diarrhea - Watery, Bloody, Mucus present Colic Depression Prevention/Treatment: Good sanitary conditions, especially clean water is essential in preventing transmission of cryptosporidium. Isolation of sick calves will help reduce the effect on the overall herd. There is some good effect of calves given adequate colostrum, however this is likely helping by reducing other pathogenic loads rather than a direct effect on Cryptosporidium, itself. Farmatan fed prior to calving has been shown to disrupt the life-cycle and reduce transmission from the cow. The direct action of Farmatan on the parasite makes it an excellent choice for treating calves. Learn more about the positive effect of Farmatan's active ingredient HERE. E Coli Escherichia Coli is a bacterial infection that affects calves within the first week of their life. The bacteria colonize in the lower intestine and produce a toxin. The toxin causes excessive secretion of fluids. The zoonotic disease has special importance in food safety and human health. Colostrum and natural immunity are often not sufficient in preventing infection in cases of high bacterial concentrations. Clinical Signs Diarrhea - Creamy, Yellow Abdominal Pains Fever Vomiting Prevention/Treatment: The best prevention methods for E. Coli include: clean water, dry bedding/environment, isolation of infected animals, and vaccination. Treatment with antibiotics and oral fluids have great benefits in reducing clinical symptoms of the disease. Farmatan has been shown to reduce bacterial load and help prevent infection. Learn more about the positive effects of Farmatan's active ingredient HERE. Rotavirus Rotavirus in calves is caused by a virus belonging to the Reoviridae family, as a non-envelope RNA virus. Rotavirus is thought to be the most common cause of neonatal diarrhea in calves. The virus tends to affect calves between the age of 1-day-old up to a month, with most cases presenting within the first week of life. Shedding and reinfection can happen in older calves and cows. Clinical symptoms are rarely present after the first month of life; older animals tend to either be carriers or asymptomatic. The majority of herds have some level present, with transmission likely happening during or shortly after birth. Clinical Signs Diarrhea - Pale Yellow, Bloody Dehydrated Dull calves Reluctant to drink Prevention/Treatment: The ideal scenario is to prevent infection through, sanitary facilities (calving barn), outdoor calf housing, and a good vaccination program. Colostrum will provide much needed antibodies, protecting the calf before their immune system is fully developed to combat the disease. Farmatan fed prior to calving can help reduce the pathogen load of the cow, reducing the likelihood of transmission. Farmatan supplemented in the milk has been shown to decrease the virus' ability to cause infection and clinical disease. The best treatment for calves already presenting clinical disease is to administer oral fluids/electrolytes to rehydrate the calf. Learn more about the positive effect of Farmatan's active ingredient HERE. Salmonella Salmonella infection of cattle is caused by a variety of species within the family. While the disease is uncommon in cattle with little effect on calf health, it has massive implications for human health and food safety. The bacteria spreads through direct contact or contaminated feed & water. This disease is highly regulated by the USDA. The most severe cases of salmonella affect calves between the ages of 7-10 days old. Clinical Signs Diarrhea - Bloody (flakes of slough tissue), Watery, Mucus present Lethargic Fever Prevention/Treatment: Prevention is always the best option: provide clean water, feed, and bedding. Isolate infected animals, ensure adequate colostrum intake, and develop a vaccination program with your veterinarian. Treatment with antibiotics and fluids (oral or intravenous) greatly increases the survival rate of calves infected with Salmonella. Farmatan has been shown to help reduce the likelihood of infection by protecting the gut, and reduce recovery time of infected animals. LEARN MORE ABOUT IMOGENE INGREDIENTS PRODUCTS Paul Mitchell & Paul Martin on RFD TV Rural America Live! Cattle Industry News USDA Gives Bleak Timeline For Mexico Cattle Restrictions According to MeatingPlace.Com, the USDA has confirmed there will be no holiday gifts for Mexican cattle producers this year. Earlier this month, APHIS restricted all Mexican animal commodity imports following the detection of New World screwworm (NWS) in a cow in the southern Mexican state of Chiapas. Mexico's chief veterinary officer alerted USDA in late November. Dr. Rosemary Sifford, the agency's chief veterinary officers, stated to media that APHIS's restrictions will “likely” remain in place through the holidays, with “full resumption of live animal movements” after incremental changes in early 2025. She went on to say that while the U.S. continues to work very closely with Mexico and has agreed to protocols, it will take some time to implement these due to multiple steps needed to resume trade. Additionally, USDA announced $165 million in emergency funding to protect U.S. livestock from NWS, which are fly larvae that infest living tissue and cause infection. Canada Plans For U.S. Trade War Canada's federal and state governments are planning measures in response to President-elect Donald Trump's threatened tariffs. Prime Minister Justin Trudeau met with provincial leaders to discuss retaliatory actions. Canadian Finance Minister Chrystia Freeland said after the meeting that "a number of premiers spoke out strongly in favour of a robust Canadian response to unjustified tariffs." In a social media post last month, Trump accused Canada and Mexico of allowing drugs and illegal immigrants into the United States and vowed to slap a 25% tariff on imports from both neighbors immediately on taking office on Jan. 20. Such an act would contradict the 2020 US-Mexico-Canada Agreement (USMCA), a modest update of the preceding North American Free Trade Agreement (NAFTA), which Trump signed during his previous term in the White House. Low U.S. Beef Inventory Argues Against Tariffs A former Canadian Cattle Association president Dave Solverson has urged farmers north of the border to utilize their relationships with fellow beef producers to try to counter US President-elect Donald Trump's threatened tariffs. Solverson said with herds in both countries at their smallest in many decades, extending possible 25% tariffs on Canadian imports makes little sense in the beef business. He said sales of Canadian stock to U.S. packers and feedlot operators are an important source to fill in increasing production gaps especially in northern states, according to Solverson, who led the Canadian Cattle Association from 2014-16. Solverson recalled that the community of North American beef producers forged alliances a decade ago to oppose mandatory country-of-origin labelling. Those coalitions with both state and national producer groups “really proved beneficial for both sides,” he said. Canadian farmers were able to convince their U.S. counterparts “about how important it was that they could top up their pens with a good group of Canadian cattle.” Questions About USDA's Electronic EID Requirements Answered There are still lots of questions about USDA's Electronic EID requirements and if you are confused don't worry you are not alone. Merck Animal Health has fielded many questions about the new electronic (EID) rules for livestock moving across state lines. As a leading provider of EID tags and readers through their AllFlex Brand, Merck Animal Health is helping support cattle producers in their decision-making with expertise and solutions. As part of that effort, Merck Animal Health has provided some clarity to the tagging system. We have all of those links and easy to follow information HERE. King Ranch Institute For Ranch Management Accepting Applicants for 2025 Wanting to make a change this upcoming year? Well, we all do. The King Ranch® Institute for Ranch Management (KRIRM) offers the premier Master of Science in Ranch Management degree. They prepare those with a passion for ranching for the next step in their career as ranch business managers. Their master's degree program offers a unique multidisciplinary approach to ranch management. They teach students how to manage ranches, but also how to progressively think their way to success and innovation for the industry. The King Ranch Institute for Ranch Management curriculum sharpens students' skills and knowledge in the areas of animal science, wildlife science, range science, business, accounting, finance, and leadership. External learning opportunities include summer internships at ranches across the United States, projects that focus on real issues facing partnering ranches, and workshops with industry professionals that cover a variety of ranch-related topics. The King Ranch Institute for Ranch Management is seeking applicants for 2025 that have a Bachelor's degree and at least 2 years' work experience in ranching. If you're ready to take the next step and earn a Master's degree and fast forward your management career, They encourage you to apply. Click HERE for more information. Christmas Gift Ideas For That Hard To Shop For Person Great handmade items along with Ranch It Up swag and merch can be found online HERE! 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Call or Text your questions, or comments to 707-RANCH20 or 707-726-2420 Or email RanchItUpShow@gmail.com FOLLOW Facebook/Instagram: @RanchItUpShow SUBSCRIBE to the Ranch It Up YouTube Channel: @ranchitup Website: RanchItUpShow.com https://ranchitupshow.com/ The Ranch It Up Podcast is available on ALL podcasting apps. https://ranchitup.podbean.com/ Rural America is center-stage on this outfit. AND how is that? Tigger & BEC Live This Western American Lifestyle. Tigger & BEC represent the Working Ranch world and cattle industry by providing the cowboys, cowgirls, beef cattle producers & successful farmers the knowledge and education needed to bring high-quality beef & meat to your table for dinner. 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D'abord "WC" signifie "Water Closet," c'est a dire litteralement placard ou cabinet à eau Et, en effet, le W se prononce V. Cela semble étrange maiss'explique par l'influence des langues germaniques, en particulier l'allemand, sur la notre.Car en allemand, la lettre "W" se prononce comme un "V" en français, comme dans le mot wagon. Or c'est l'usage de cette prononciations'est propagé à travers les pays germanophones mais pas que ! Elle a influencé d'autres langues, dont la notre.. Cela explique pourquoi, lorsque le terme "WC" s'est introduit dans le vocabulaire français, il a été prononcé dès l'origine"vé-cé".Vous le savez les termes ou expressions issus de langues étrangères gardent parfois leur prononciation originale ou la prononciation d'une langue dominante (comme ici l'allemand). Dans le cas des "WC," l'influence germanique a donc un impact direct.Puisque nous parlons de WC saviez vous que qu'en tirant la chasse d'eau, des milliers de minuscules particules peuvent être projetées dans l'air — c'est ce qu'on appelle l'effet d'aérosolisation. Le phénomène de l'aérosolisationLorsque la chasse d'eau est tirée, le vortex de l'eau peut provoquer une dispersion de fines gouttelettes d'eau contaminées par des bactéries, des virus, et des particules fécales dans l'air environnant. Ce phénomène est particulièrement visible dans les toilettes sans couvercle. Une étude de l'Université du Colorado a montré que ces particules peuvent atteindre jusqu'à 1,5 mètre de hauteur et rester en suspension dans l'air pendant plusieurs minutes, voire heures, selon la ventilation de la pièce. Conséquences pour la santéLes particules d'aérosol peuvent contenir des pathogènes comme E. coli, Clostridium difficile, et même des virus comme le norovirus. Bien que l'exposition à ces aérosols ne soit généralement pas suffisante pour provoquer une infection chez les personnes en bonne santé, elle peut poser un risque pour les personnes immunodéprimées. Comment limiter ce phénomène ?Pour réduire l'aérosolisation, il est recommandé de fermer le couvercle des toilettes avant de tirer la chasse, lorsque cela est possible. Cette simple habitude peut limiter la propagation des particules. En plus, un nettoyage régulier et une bonne ventilation sont essentiels pour maintenir une bonne hygiène dans les salles de bain. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
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On tomorrow's episode of The Wholesome Fertility Podcast, I welcome Dr. Sarah Wilson of @embracefertility. Dr. Sarah Wilson shares her personal journey with reproductive health and how she overcame challenges with her period and fertility. She emphasizes the importance of understanding one's own body and advocating for oneself in the medical system. Dr. Wilson discusses the role of the immune system and gut health in reproductive health, highlighting the connection between inflammation, gut bacteria, and hormonal balance. She explains how basic blood work can provide valuable insights into one's health and offers practical tips for addressing gut health issues. Dr. Sarah Wilson discusses the importance of gut health and its impact on overall well-being. She explains how the gut microbiome plays a crucial role in maintaining a healthy immune system and how imbalances in the microbiome can lead to various health issues. Dr. Wilson emphasizes the need to create a hospitable environment for beneficial bacteria to thrive and shares insights on the use of probiotics and spore-based organisms. Dr. Wilson provides practical tips for improving gut health, such as eating whole foods, avoiding processed foods, and managing stress. Guest Bio: On today's episode of The Wholesome Fertility Podcast, I welcome Dr. Sarah Wilson, ND. Dr. Sarah Wilson discusses the importance of gut health and its impact on overall well-being. She explains how the gut microbiome plays a crucial role in maintaining a healthy immune system and how imbalances in the microbiome can lead to various health issues. Dr. Wilson emphasizes the need to create a hospitable environment for beneficial bacteria to thrive and shares insights on the use of probiotics and spore-based organisms. Dr. Wilson provides practical tips for improving gut health, such as eating whole foods, avoiding processed foods, and managing stress. Takeaways: Advocate for yourself and seek answers when faced with reproductive health challenges. Understanding the role of the immune system and gut health is crucial for reproductive health. Basic blood work can provide valuable insights into one's health and help identify patterns and tendencies. Addressing gut health issues, such as inflammation and imbalances in gut bacteria, can positively impact reproductive health. Maintaining a healthy gut microbiome is essential for overall well-being and a strong immune system. Creating a hospitable environment for beneficial bacteria to thrive is crucial for gut health. The gut-brain connection and the enteric nervous system play a significant role in gut health. Managing stress, eating whole foods, and avoiding processed foods are important for improving gut health. Dr. Sarah Wilson, ND, is the visionary founder of Advanced Women's Health, leading a healthcare revolution across Canada with clinics in Ontario and British Columbia. Overcoming her own health challenges, Sarah is dedicated to empowering women to reclaim their vitality naturally, merging research-backed expertise with her passion for Naturopathic Medicine. Beyond her professional pursuits, she is the Mom to two latino boys under 5 and is a self-proclaimed personal development and mindset fanatic. www.advancedwomenshealth.ca Instagram: @embracefertility @drsarah_nd @advancedwomenshealthclinics https://www.youtube.com/@embracefertility https://www.linkedin.com/in/naomi-woolfson/ For more information about Michelle, visit: www.michelleoravitz.com The Wholesome FertilityFacebook group is where you can find free resources and support: https://www.facebook.com/groups/2149554308396504/ Instagram: @thewholesomelotusfertility Facebook: https://www.facebook.com/thewholesomelotus/ Transcript: Michelle (00:00) Welcome to the podcast, Dr. Wilson. Sarah Wilson (00:02) Thank you so much for having me. I am so excited. I just really can't get enough of sharing all of the information that women need about reproductive health and empowerment. So thank you for having me. Michelle (00:14) Love it. So I'd love for you to share your background and how you got into the work with reproductive health. Sarah Wilson (00:21) It's such a huge conversation, I think such an important one because for so many of us, we get into it because we needed the medicine, right? And we explored that. So my story I always say is a really winding one. I was in and out of hospital my whole life until I was 18 and I was diagnosed with celiac disease, but I didn't fit the bill. And it was a naturopathic doctor that really pushed for that initial diagnosis. And so then, as we all do, Michelle (00:28) Mm -hmm, yeah. Mm -hmm. Sarah Wilson (00:49) I avoided my calling and was trying to figure out how to recover and how to work within this and lost my period for almost five years. And so during this time, I was a researcher and I was seeing different naturopathic doctors. I was seeing different conventional doctors and specialists and people just kept saying they didn't know what was going on and they couldn't figure out why I was, like I wasn't exceptionally lean during much of that period of time. Like they just couldn't piece it together. Michelle (00:58) wow. Sarah Wilson (01:18) I had a doctor, think it was 21, 22, that was like, you might never have kids on your own. If you wanna get pregnant, come back to me, I'll give you a pill, we'll wish you the best. Michelle (01:28) So nonchalant. Sarah Wilson (01:31) And I just, I always say there's a few breakdown to breakthrough moments in my life and that was a big one where I was just like, absolutely not. I have the world available to me. I have all of this research. There must be something I can figure out. So that proceeded to really get me to push to work and find the research and piece things together. And I did bring back my period. And then when it came back, it was exceptionally painful. I was passing out. I had been on birth control. Michelle (01:37) Mm -hmm. Yeah, good. Mm -hmm. Sarah Wilson (02:00) since I was 13 because of the amount of pain and heaviness. And so that's what it was like, okay, now we have to navigate this world of endometriosis and what that means. so yeah, now fast all the way forward, I became an astrophysicist doctor. I have two babies with two tries. I do not live in chronic pain and I'm just so passionate about taking all that research. I had to figure out myself and... Michelle (02:09) Mm Mm Mm Sarah Wilson (02:26) had to bring into practice and navigate how to bring into practice to now be able to give that to patients across advanced women's health clinics in Canada. it's just, it's a very empowering end to a really challenging journey, which I think so many people listening have. Michelle (02:44) Yeah, for sure. What I love about what you were saying is that knowing that inner knowing you're like, no, absolutely not. Like you knew it in your heart. Because a lot of people hear that. And then they're like, okay, I guess that's just my fate. And I love, you know, I love when people are like, no, I'm gonna take no for an answer. I'm gonna figure it out. and it's also an intuition. It's like your own intelligence within you telling you, no, there's more to look into. I had a similar thing a little different, but similar. so what was it, let's kind of go back just because people might be in similar situations with their period, listening to this. What was it that really caused the five years without period? was it being on a pill for a long time? What was it that caused that? Sarah Wilson (03:29) So I was actually, my presentation of celiac disease was very different. I was 100 pounds heavier than I am now. I perfectly, I exercised and I was obese. And so what, the brain is such a beautiful thing. And what I believe happened is that being obese, going through puberty programmed my brain for what body fatness, quote unquote, I needed to have in order to be safe to have a baby. Michelle (03:36) Mm Mm Mm -hmm. Mm -hmm. Sarah Wilson (03:59) And so for most people, they lose their periods around 16, 18 % body fat. I tend to hover around 23, 24. If I dip below that, then my period starts to go as long, it goes wonky. It's much better now, but the research suggests that when you have inflammation interacting with your brain, when you have cortisol interacting with your brain, what happens is we actually change how sensitive we are to the signals between the brain and the ovaries. Michelle (04:08) Mm Mm Sarah Wilson (04:28) And so I think that in combination with all these set point theories, there's so many things happening now in the world of set points, that combination is what it was. So for me, getting my inflammation under control, which we'll talk about, getting an understanding that I had stress, but it was physiological stress. I had nutrient deficiencies, I had bacterial overgrows, I had inflammation, like I had all of those pieces. that were interacting with my brain and my hormones. And so I just needed to go through step by step. I needed to work on my gut microbiome. I needed to work on the nervous system component. But fundamentally, I needed to understand that my body, the way it works and its sensitivity is set at a slightly different point than other people's. Michelle (05:18) Yeah, well, for sure. I mean, I think that that's really at the crux of everything is that everybody has their own different set point and different like, you know, responses, their bodies respond to different foods, different environments, different stress factors, just so many things. And I think that that's the key. I often see a lot of people sometimes come in to see me and they're well, I'm taking this kind of like, combination herbs that I saw online or, you know, so, that's, that's one of the things that I really try to stress to people is that everybody's so different. And so when you were going through that, you were uncovering it. Obviously you had a natural path that you were working with. Yeah, multiple. So they, you had a team. Sarah Wilson (05:58) And multiple. Yeah, absolutely. And I think I always say I'm the most energetic scientist you'll ever meet in your whole life. Like data informs every single decision. And then you sit in front of the person in front of you and you say, OK, what's their energy? Right. Like what? How do you need to to build those things together? And so, yeah, I had a team I had. Michelle (06:09) Mm Mm right. Totally. Sarah Wilson (06:23) And I had multiple naturopathic doctors try to work their way through it. I had OB -GYNs and my family healthcare team trying to help navigate it. And it was just, I was in the typical situation. I was in the situation that 90 % of my patients are in. Everyone's like, you're fine. It's fine. Your blood work is fine. Right? And that's, think, even for me doing research, one of the projects I was on was we were studying metabolically healthy people, metabolically unhealthy people. Michelle (06:41) Right, exactly. Yeah. Sarah Wilson (06:52) We were studying them in lean and obese categories. And so the labs going through and they're pulling all this data. And it was the first time that I'm sitting there going, huh, okay. So we can have people that are metabolically very healthy and overweight. And we can have people that are very lean and extremely metabolically unhealthy. And this was, it was such a formative experience because I remember sitting there going. Michelle (06:55) Mm Mm -hmm, right. Sarah Wilson (07:20) The blood work, the way we're reading it right now means nothing. Right? Like we need to be rude. Michelle (07:25) There's so much more. It's just a snapshot. It's like a small, it's a small little slice. And I think that's something that I often see too, is that we make such generalized assumptions based on such a small little snapshot. And while that snapshot is very important, it's, it's kind of a piece to the puzzle. It's not the end all be all it's part of the whole picture. Sarah Wilson (07:28) Exactly. Exactly, and if we use a conventional reference range that's defined based on disease, like I think in North America, we've really lost the understanding that there's a line between health and disease. Like you don't just jump from one to the other like long jump, right? It's not like I'm healthy today and tomorrow I have a disease. Like there's this spectrum of dis -ease as we make our way to a condition. And I think identifying patterns in labs. and identifying tendencies is arguably more important than the snapshot itself, you're 100 % correct. And so we have to look at that data holistically and say, how is that changing? How is that modifying over time? But also I think there's so much research now where we can give people back the keys to the castle with that basic blood work, right? Even for example, everyone has had what we call a complete blood count. We've had multiple of them. So that's... A complete blood count is when we're looking at your red blood cells and your white blood cells. We're looking at the breakdown of those things. It's the thing you get when you walk into the doctor's office, when you get when you walk into the hospital, et cetera. They're always just saying, what's your white blood cells? What's your red blood cells doing, et cetera. And there's two white blood cells called neutrophils and lymphocytes. They are just representing two aspects of our immune system that are fighting bacteria and viruses and they're helping to support the system. But there is a ton of research coming out to show that the ratio between neutrophil and lymphocytes can tell us about the inflammatory status of the body. So if your NLR, as we call it, neutrophil to lymphocyte ratio, is higher than 2 .5 or 3, chances are you've got an immunological underpinning to what's going on. And so for me with endometriosis, I was in the hospital a while ago now, and I was having a flare, and I was worried about ovarian torsion, because at one point I had had a 10 centimeter endometrial. Michelle (09:30) Mm -hmm. Sarah Wilson (09:40) like it was very, very large and it's not there now, but I just wanted to go in and make sure that there wasn't something happening because it felt different. And my NLR was six, but outside of that, it was one or two. So this is something I always say to patients, you can even empower yourself just looking at that number and being like, if that number is jumping high and it's correlating with my symptoms, if I have worse menstrual pain or worse mood challenges or Michelle (09:42) Mm -hmm. Mm Mm Mm -hmm. Sarah Wilson (10:08) I get pregnant and these things jump and then I have a loss, what could that be telling you about your immune system? And I think there's such simple things. Of course, we can run super comprehensive panels of labs and get all of the autoimmune tests. And like I've heard you talk about them on the podcast before, right? You can get really comprehensive panels and that's wonderful. And I love that as a doctor and a researcher, I love data. But what I love even more is saying, let's look at the past two or three years. Michelle (10:26) Mm Mm Right. Sarah Wilson (10:37) What are these basic blood markers telling us about your tendencies and how much we need to dig into different components of health, like your immune system, your blood sugar, those types of things? Michelle (10:48) So you could see this basically on just general blood work. Sarah Wilson (10:53) Exactly. And so that's where I think for me. Michelle (10:55) And do people often look like, do doctors even know to look for that specific thing? So it's kind of one of those things that people don't really look for, but you can kind of dig up your own stuff and just look at the ratio yourself. Sarah Wilson (11:07) Exactly. Exactly. And that's why I think I come on these podcasts and I do these things because not everyone has access to a naturopathic doctor. Not everyone can be a researcher. Exactly. So to be able to look at that and start to question, even when I was in the hospital, I was like, are you concerned about that? And they're like, maybe you have a bacterial infection. It's not a big deal. Okay. Okay. Right? But it's... Michelle (11:16) Yeah, that's very empowering. Mm -hmm. Yeah. Sarah Wilson (11:30) It's those things that I want people to be able to grab onto and access for themselves because what I know to be true in my practice, seeing so many people, is when you give women access to information about their bodies, they change communities, households, everything. Like it is the most empowering thing for me to come on a podcast and talk about something and then... Michelle (11:46) Mm Yeah. Sarah Wilson (11:57) get someone message me and be like, my friend of a friend of a friend told me to look at this and now I'm concerned about it. And I'm like, yeah, you should probably get that investigated. And then it's ovarian cancer. You know what I mean? Like this is how powerful just these conversations are. Michelle (12:08) my God, yeah. Yeah, it's very powerful. mean, obviously when you do see that something's off, it'll get you at least to take the next steps or to investigate it more because you can't really make, you know that something's going on, but you have to like really move further and see what it is. But at least it's going to be an alarm to let you know something's going on. Sarah Wilson (12:35) Mmm. And a direction, right? I, every day, pretty much at this point, I'm talking to someone who's like, everything I was told was unexplained, right? And in the fertility world, if you're unexplained infertility, you either have a baby or you don't, right? So there's clarity in that, no one's saying, your infertility is in your head. But in every other aspect, there's not those clear end points. And so, Michelle (12:40) Mm Mm -hmm. Mm Sarah Wilson (13:07) if someone's dealing with chronic pain and they aren't getting investigated for endometriosis or some other condition, they can be told it's all in their head. So even if they can see on basic blood work, one or two things that are off, it's like, there, go there, let's do this. And I think that's what's so exciting to me. Michelle (13:24) Mm -hmm. Right, right. Yeah, definitely huge. So talk about the immune system. this is one of the things that you can look at, I know that there is a lot of a connection with autoimmune conditions and the gut health and, high inflammation and leaky gut. So talk about that, how people can look into it and how they can address it. Sarah Wilson (13:53) Absolutely. So I actually also was a microbiome researcher at one point in my profession. It's so important. And even now, like post pandemic, we've seen it so much more important because historically, what do we always say? Is 60 to 80 % of your immune system lives in your gut. Okay. So there is within your gut, there is, it's so interesting. Picture a PVC pipe, right? On the inside, if there's Play -Doh. Michelle (13:59) awesome. Amazing, though, but it's so important. Mm Mm Sarah Wilson (14:23) that's where the bacteria live, right? But that's actually outside of your body. And so that play -doh is either poop, in those of us who are lovingly chronically constipated, or it's the mucosal lining that the bacteria live within. So that's where the immune system is really, really critical, is within that putty lining. And so what happens is that immune system's job, because it's technically outside of your body, mouth. Michelle (14:26) Mm Mm Sarah Wilson (14:51) all the way down to your anus is outside of your body. Its whole job is to say, are you a food and you're safe? Are you a bacteria and you're safe? Are you a virus and you're not safe? Are you a bacteria and you're not safe? And the whole job of that immune system is to sample and navigate. Do I need to kick off an inflammatory response or do I not? Am I safe or am I not? And so what we're looking at is when we start to have allergies. and we start to have food responses and all these food sensitivities when we start to have bloating and gas changes in bowel movements. That's all telling us that our immune system either one has identified a bacteria or virus that needs to go and it's kicking off a response to it or two, it has what we call lost oral tolerance. It has lost the ability to know between what's good and what's bad. Michelle (15:46) Mm. Sarah Wilson (15:47) And so in both of those situations, that is going to result in inflammation, not just local to our gut, but throughout what we call our peritoneal cavity, right? So that's gonna be your ovaries. I always say, your bowel and your ovaries and your uterus are friends. Like for those of you who can't see it, they're touching, they're friends. So we have that inflammation in our reproductive system. We have that inflammation affecting our liver. then it goes into our bloodstream. It affects our joints, it affects our brain. That's why we talk so much about the gut brain connection, because there's that inflammation there. But as a practitioner, my job is to sit here and say, is it that we have so much inflammation? There is this absence of an ability to regulate, should I fight this or should I not? Is it that there's so much damage being caused by inflammation that now we have leaky gut or impermeability, right? Because the immune system will cause damage and it's trying to fight something and there's collateral damage. So is it that or is it that there's bacteria that need to be modified? And so I think it's really helpful, even like thought experiment to think about it in that way, because so much of the time when it comes to the gut, we Michelle (16:43) Mm Mm Sarah Wilson (17:05) are assuming that our symptoms are wrong. Like, what's wrong with my gut? Right? Like, we're a victim to it. Like, our immune system is doing something bad. But nine times out of 10, it's trying its best to protect us. And so our job is to say, what is it protecting you against? Michelle (17:08) Mm -hmm. Right. Mm Mm Right. Sarah Wilson (17:25) So when we're navigating and we're going through then, we hear all about probiotics and we hear all about these different things and all of them can be helpful and have their place, right? We hear about armor colostrum all the time these days on different podcasts, right? We hear about all these things. And so I always say, think about them and put them in the context of what I just said. So if we don't have enough good bugs and we add probiotics, which are good bugs, Michelle (17:36) Mm Mm right, yeah. Sarah Wilson (17:52) then that will take us so far. for, again, for those of you who can't see, I've got my hands up, right? Picture it like a bar graph. So if you don't have enough good bugs and that bar is low and you have too many bad bugs, then the dominant state is bad bugs. So if you add a whole bunch of good bugs, then eventually you can turn that dominant state into good bugs. But probiotics are transient, they leave the system. So you still have that low grade bad bug situation. Michelle (18:06) Mm Sarah Wilson (18:21) So this is where we hear about berberine, right? We hear about oregano, we hear about black cumin seed, we're hearing so much about all of these herbs now, because what they're doing is they're breaking down the bad bugs to allow the good bugs to grow, to repair the lining. it's, there's such a huge dance with the bugs in the gut and the immune system and how that affects the rest of your body, but what we know for darn sure is that Michelle (18:23) Mm Right. Right. Sarah Wilson (18:49) There are overgrowths that are happening more than they ever have been before of bad bugs. We know that. Michelle (18:55) Right. So we're talking about things like SIBO, you know, just that, because that ultimately it starts to kind of go from like the bowels all the way up. Sarah Wilson (19:04) Yeah, exactly. So SIBO is small intestinal bacterial overgrowth. So it's overgrowth of good bugs in the small intestine. We also have what we call CFO or overgrowth of yeast in the small intestine because the immune system can't defend against the yeast. Then we have bad bugs and parasites, right? So this is where we hear an overgrowth of, I'll throw some names, like Pseudomonas, C. difficile, Clostridium species, E. coli. We have an overgrowth of bad bugs in that situation. And those can be Michelle (19:11) Mm Mm Mm Mm -hmm. Bye. Mm Sarah Wilson (19:34) upper but they can also be lower down. And so that's always what we're navigating is saying, okay, is there, if you have an overgrowth of good bacteria and you add more good bacteria, you're gonna be the person who feels awful on probiotics. You take them, you're gassy, you're distended, okay, in that, yeah. Michelle (19:49) Right. Unless, unless they're spore based. Sarah Wilson (19:56) The SBOs are such an interesting conversation. They're such an interesting conversation because most of the research is coming out of two labs. And so I agree to some extent and I'm pensive. Yeah. Michelle (19:59) Yeah. Mm -hmm. Okay. No, tell me, tell me. I want to hear it because, because I've always been told and I've always learned that spore -based probiotics, because, they, they bypass the small intestine, they go all the way down to, you know, the colon that, and then they, and then they flourish and they change the pH and they, they make it so that it's more hospitable for the good bacteria to grow and not the bad bacteria. A lot of times there's like die -off symptoms and it Sarah Wilson (20:32) Exactly. Michelle (20:36) kind of shifts, even though it's transient, it does shift the pH to create it where it's better for a healthier environment. Sarah Wilson (20:47) Absolutely. So it's just like that bar graph, right? I always say if you give the environment for the good bugs to grow and there's not too many bad ones, then they will grow and take over. If you ever, I always tell people picture like an octopus or a cuttlefish, you know they change colors really rapidly? Our bacteria do the same thing. It's called quorum sensing. And so essentially if you create a hospitalable environment, you have enough mucus. This is the other thing, right? Bacteria need mucus. Michelle (20:49) Mm Yeah. Yeah. Mm -hmm. Yeah. Mm -hmm. Mm The mucosal lining. Yeah. Sarah Wilson (21:13) Exactly. So if you have that integrity, you add probiotics, and then you can change from a red environment, inflamed, the pH is off, there's bad bugs growing to a good environment. If you don't have that mucosal lining, if your immune system is too grumpy, or if you're in a situation where there's too many bad bugs, then you can't fix it by adding more. Michelle (21:17) Mm -hmm. Mm Mm Mm Sarah Wilson (21:40) And so that's where we're using antibiotics and antimicrobial herbs and things like that to get that down. Going back to the SBOs, the thing I find really interesting is there's so many, I could like nerd out on this stuff all day long as you can tell, but there's so many factors, right? So when we talk about it bypasses the small intestine, what they mean in that situation is that all bugs are either acid sensitive, temperature sensitive, Michelle (21:54) It's great stuff though. Sarah Wilson (22:09) oxygen sensitive or yeah, I went through acid. Those are honestly the main ones. There's nitrogen sensitive, things like that, but those are the main ones. So what they're saying is the acid sensitivity means that they will get, and the temperature and oxygen sensitivity means they're gonna get lower down. But what we're seeing more and more and more is that people's stomach acid is off, their pH is off throughout their whole system. They have all kinds of, Michelle (22:32) Mm Sarah Wilson (22:37) you know, temperature sensitivity changes. And we have all kinds of changes in the hydrogen, methane and oxygen levels within our gastrointestinal tract. So what happens is we're not actually controlling where it's going. We're controlling at what environment it takes hold. And because there's so much dysfunction within the gastrointestinal tract in so many of our patients, I'm concerned that it actually could take hold. and be present at higher levels of the gastrointestinal tract contributing to issues. And I've seen some... Yeah, that's BOs. Yeah. Michelle (23:10) You mean the spore based ones, the spore based? you, because from what I understand, looking into it is that it won't activate until it gets to the large intestine. Sarah Wilson (23:23) And that's based on the pH, the oxygen level and the temperature and all of those pieces. Michelle (23:29) Okay, I see. So you're saying that it could be a different pH and everything will shift if things are so off, up, you know, higher. Got it. Sarah Wilson (23:36) Exactly. Exactly. And I've seen severe constipation in patients that take SBOs. It's like the only side effect I see, because you're right, there is a lot less bloating gas, those like three to five day battle between the good and the bad bugs. There's less of that for sure. But I have seen like enough patients that got me saying, okay, what's going on there that take it. Michelle (23:47) Mm Mm -hmm. Mm -hmm. Yeah. Mm Sarah Wilson (24:04) and immediately they're super constipated. So we actually use them a lot in diarrhea because of the benefit of that. But it's definitely a space I'm watching the research. It's super interesting. I think just like, so I was, my God, how many years ago now was I a probiotic researcher? least 10. It's a different world, right? Like how exactly, so. Michelle (24:10) Mm -hmm. Yeah. Mm -hmm. yeah, they're learning so much so fast. Yeah. Sarah Wilson (24:30) Exactly. So that's where I always say, you know, you're a good practitioner when you want to refund everyone every five years. You're like, what was I doing? So I think it's just an evolving conversation, but they definitely do have utility for sure. I think there's just, for me, just having been in a research environment, I know how controlled all of those situations are. And so then when they come out into our patient situations, Michelle (24:35) Yeah. Yeah. Sarah Wilson (24:56) We just need to apply different lenses of thought to it. Michelle (25:01) Or I mean, you can also add something like Trifola while they're doing that so that you're kind of like counteracting the constipation aspect or maybe some more fiber eventually when they're ready, you know, because sometimes too much of that when things are not great can exacerbate. Sarah Wilson (25:17) Absolutely. And like we have studies now that are coming out to show that it's alarming. Over 50 % of people have what we call retained fecal matter, which is like constipation when they don't know constipation. And so I think there's so much that we're finding out and there's so much that's going on within the gut microbiome world that will be. Again, I'm just always so curious to see where it goes and to see what happens with it. Because even I wrote a book in 2018, I guess. So I was writing in 2017 on insulin resistance and how that worked. And like I talked about in Cretins in a big section of that book. This was like pre -Ozempic days. And people at that point were like, what is she talking about? And now it's so accepted. And that's what six years later, right? They're just like, of course. Michelle (26:08) Yeah. Sarah Wilson (26:11) So, so much changes so quickly. And I think just staying on top of it is something I value so much. Like even today, I'm teaching an intensive on post -viral immunology for other practitioners, right? So, I'm always trying to navigate what do I see in practice? Because we see thousands of people in advanced women's health. And how is that showing up in the research? And how do we mesh those things and adapt with those things? Because things change so quickly. Michelle (26:14) Yeah, for sure. Mm yeah, definitely. No, I agree. mean, everything just kind of out does itself. Something new comes along. what I find really fascinating is the gut brain relationship and the enteric nervous system and also the vagus nerve and how that impacts. It's kind of like the go between our brain and our gut. And, and also Sarah Wilson (26:50) Yeah. Michelle (27:01) the research on that where they've done like studies on meditators and like people in Tibet, Tibetan Buddhists, compared to people that are neighbors that eat the same food, they live in the same environment, but the gut microbiome of the meditators is so much more enriched. So it's kind of like a buy between, yes, we could work from the gut to the brain, then we can also work from the brain to the gut. And it's pretty fascinating. Sarah Wilson (27:12) Yeah. Yeah. Absolutely, and even to see the amount of research on people's levels and how that is directly related to yeast infections. We know that that whole gastrointestinal tract, vaginal microbiome, they are so, so, so closely tied to our nervous system and stress response. There's so much, I do. Michelle (27:34) Mm Mm That's interesting. Yeah. Sarah Wilson (27:52) stool testing on myself pretty frequently. I would say even more so than patients, I do it on my family. And it's so interesting to see how it shifts because again, diet and lifestyle can stay very similar. So it's like interesting what caused that shift, what caused that shift, how was stress involved with these things. it's, yeah, it's so fun. It's so fun. Michelle (27:58) Yeah. Mm -hmm. Yeah, it's fascinating for sure. And then also, think about the gut microbiome, I think about the changes, I think about inflammation. I think about the additives we're eating and we're exposed to. mean, those are the biggest things because it feels like it's outside of our control. I mean, it kind of is until we know about it. It's, know, we go eat some places, we have no idea what they're adding and we know that Sarah Wilson (28:33) Mm Michelle (28:40) thickeners, I mean, there's so many things that can be added. We know that they can really throw off the gut microbiome and that throws off inflammation. So it's kind of like an unintended consequence because you're not, most of us don't know that unless we're doing what we're doing and learn about it. Sarah Wilson (29:00) And then you're looking, is there SLS in this? Is this disrupting my microbiome? Michelle (29:04) Yeah, but that's what it is. And that's why when people say, I guess, to simplify it is just don't eat processed food as much as, try to avoid it as much as possible. Because even like the good kind can impact your gut. mean, like good processed food, because of all of the excess ingredients that they add in there, that could really throw off your microbiome. That's why when people say just, I guess, like, if you want to say something that's more generalized, is more whole foods, foods that come from the earth and also foods that are not sprayed with toxins, know, I mean, to try to avoid it. It does feel like an uphill battle. Sarah Wilson (29:44) Patients are so overwhelmed, right? It's you're trying to eat whole foods and then you look and they're like, okay, well, what about genetically modified agents? And then what about what's being sprayed on them? And I always say that in of itself is a stress response, right? So we talk about stress and then we make food such a stress. And so I always say to people, the reality is that you could probably do better than you're doing right now. Michelle (29:45) Yeah. Sarah Wilson (30:12) and what feels reasonable, what doesn't feel overwhelming, right? And we'll actually sit there and go through and say, okay, I need you to eat a low insulin demand approach, because insulin is such a huge inflammatory compound. Insulin is the hormone that controls blood sugar, but it's like 75 plus percent of us are insulin resistant in today's day and age. So it's a huge, it's an epidemic. So I'm like, okay, don't eat a ton of carbohydrates, Michelle (30:14) Mm Yeah. Yeah. Sarah Wilson (30:43) I hate good carbs, bad carbs, but berries, all of those highly colorful fruits and vegetables, don't count them. Eat away, enjoy your life. I'm not talking about that. We all know we shouldn't eat as much bread. Deep fried foods are not helping anyone, right? The starchy carbohydrates, rice, like that. We have to watch those things. We built a culture on creating addiction to carbohydrates. So we have to be careful of those things. But it's like, how can you add two servings of vegetables? If you can... Michelle (30:52) Yeah. Nope. True. Sarah Wilson (31:12) buy local and you know where they're coming from, rock on. Like it's summer here right now. There's farms that I know do not spray anything, but they cannot certify organic because they can't afford it. Okay, wonderful. I can go there, right? Buy frozen organic. It is pretty much the same price to buy frozen organic as it is to buy broccoli right now, right? And saves my life prepping it. It is picked right. Michelle (31:26) Yeah. Mm -hmm. 100%. Yeah. Sarah Wilson (31:41) It is frozen right away. There's benefits to it. So it's like, do that. Okay, then we look at our meat. How, or if you're eating meat or not, How is it being raised? Would you want to go visit that farm? Because if you would not feel good around that, then energetically that has an impact, right? What hormones are going into it? We look at those things. And the reality is, if you can't... afford to make those choices wonderful. That happens. What do we do to feel the best about the options that we have in front of us? Fundamentally, I always say balance blood sugar and a nervous system that is stable and you're not having anxiety every time you put food in your mouth because you don't know what's in it. That is going to take us almost just as far as micromanaging every piece and every ingredient. Whole foods more often eaten away that fills you up, that makes you feel good. And everything else from there is customizable. But I think I hear so many patients, they get so caught up in fresh, organic, grass fed, grass finished, researching the farm, and then they end up in McDonald's. Michelle (32:57) Yeah, that's not good. Yeah, yeah. Yeah. Sarah Wilson (32:59) because they're so overwhelmed, right? They're like, I'm just hungry. And so I always say like a happy balance is always gonna be the goal. Michelle (33:08) Yeah, no doubt, for sure. Sarah Wilson (33:10) And your microbiome loves colors and there's not many of those at McDonald's, so. Exactly. Michelle (33:14) Yeah, variety for sure. Yes, totally. And then you were talking about like symptoms even without a diagnosis, Sarah Wilson (33:24) So the blood work is one piece, right? So even without a diagnosis, you can do complete blood count. You can do something called a C -reactive protein, which is a marker of gut inflammation, liver inflammation. You can do an arethrocytes sedimentation rate. These are blood markers. But I also say, if you are struggling with joint aches and pains, if you feel like you're just getting older, if you are dealing with brain fog, if you... Michelle (33:26) Mm Mm Sarah Wilson (33:53) have pain with your periods that we have normalized so much as a society. If you have period poops, if you have PMS that is affecting your quality of life, like we have so many of these symptoms that we've been told, I'm just getting older, I have aches and pains, I'm just bloated and gassy, it's not a big deal, I just have brain fog, I'm losing my memory, right? I can't remember where I put my keys. I'm dealing with like menstrual challenge. That is all inflammation based, all of it. And as someone I think who lives in this world all the time, it's so easy to forget what it feels like to feel crappy until you get hit. And I have two small children. I have a two and a five year old. And so we're sick all the time, right? Like it's just the reality, daycare, school, people get sick. And It's so easy to just again, lose track of what good actually feels like. And it doesn't include those things, right? You should wake up in the morning feeling rested, unless you have a child who has nightmares about monkeys, which happened to me. Right? But you should be able to sustain that energy throughout the day without eating food. You shouldn't have to compromise your activity and your work schedule based on pain. Michelle (35:05) Right. Sarah Wilson (35:17) and energy levels and your menstrual cycle or your digestion. And so many people are living in that state where they are. Michelle (35:22) Yeah. And so when you do have people that come in with inflammation, what are some of the ways that you address that Sarah Wilson (35:33) absolutely. So my belief structures, there's only five to seven causes of disease, right? So we go through blood sugar dysregulation and insulin resistance, the gut microbiome, immune dysregulation, we've got liver issues, we have nutrient deficiencies, the nervous system, and then we have the components of cellular energy production, or what we call our mitochondria, right? So these are the components of health. And at the end of every piece of that, you're going to have a stress response and an inflammatory response, which is what most people are dealing with in today's day and age is they're struggling between that balance of stress response and inflammation. So my job is always going through those components and saying, which are the top two or three for you, right? If we're talking about microbiome issues and the immune system as two key pieces. And then we say, okay, let's compliment that with the nervous system because we just talked about that. If those are someone's top three pieces, then first and foremost, we have to go through and say, what are the biggest obstacles? What are your gut symptoms? Does that suggest that you might have an overgrowth of methane species? Right? Does that, that tends to be constipation, lots of gas that doesn't smell great. Is it suggesting that you have hydrogen overgrowth? Right? that's lots of gas that doesn't necessarily have a smell. We can go through, pick those apart. Do you have a history of parasites? Right, do you camp a lot? Those pieces, we're using antimicrobials in those situations to try to create some stability. We're trying to understand how that's gonna relate to blood sugar, et cetera. When it comes to looking at the immune system, there are key nutrients like vitamin D. If you don't have vitamin D, at the right level, which most of us do not, that's a master controller of your immune system. So we need to have that in place. We also need to look at your viral history. So we know right now, research is showing that you can retain components of viruses for years. We've seen that people have reactivation of chronic viruses and those are directly affecting the lining of their uterus, they're directly affecting their ovaries. Michelle (37:44) Mm Sarah Wilson (37:55) and their whole pelvic health. So in that situation, we're saying, okay, what antivirals need to come into the mix? And what do we need, again, to look at from a holistic perspective? I know you've had so many people on here that talk about NAC and N -acetylcysteine and alpha -lipoic acid and CoQ10. And oftentimes what they're doing is just helping with those inflammatory cycles. Michelle (38:22) Mm Sarah Wilson (38:22) right, they're helping to restore balance to that inflammatory pathway. And then the nervous system comes in because that affects blood flow that affects your immune system's ability to do its job. And we say what works for you? Is that nerve nerves, right? That's where our valerian our passionflower, our zycephos come into the mix and are so beautiful. Is that going to be something where it's we're looking at meditation and walking? and all of those pieces. that's really the approach I take, is I say, in those five to seven different causes that someone could have, what are the most important pieces for them? And then we dig into it at depth to say what components, whether that's using blood work, whether that's using functional testing, honestly, at this point, having seen as many patients as I've seen, sometimes it's insane. You're like, okay, I think we need anti -microbials. some valerian and passion flower, and we need to correct the nutrient deficiencies that are present with respect to vitamin D and some of those antioxidants. We need to get enough protein, more colors, Bob's your uncle. But it's, I always say, health is so simple, and we have so much time and energy dedicated to making it really hard. And... Michelle (39:31) Right. Sarah Wilson (39:42) the more sophisticated I get, the more sophisticated the research gets, the more I go down rabbit holes, the more I come back to the same things. And I think there's so much peace in that too, to know that, yes, I have a lot of patients with very chronic health issues, with very significant imbalances, but the body wants to come back to those places and we just need to figure out which levers to pull to get it back to health. Michelle (39:49) Right. I love how you put that. It's true. It's just like, are the levers to pull, to try to help it do its job. what it wants to do really, it's like its purpose. Sarah Wilson (40:24) Exactly. it's so, like sometimes you're pulling the same levers in rotation, right? You're like, okay, blood sugar, stress response, liver. And then you're like, inflammation, gut microbiome, stress response, blood sugar, liver. It's, you sometimes have to cycle back to those pieces. There's like the layers of the healing onion. So as we always say, but it's, there's so much simplicity that can be had within all of it. And I really want people to feel that because I think, Michelle (40:28) Mm -hmm. Right. Yeah. Sarah Wilson (40:50) There's a lot of energy now being dedicated to feeling like health is gate kept and it's not, right? This is why we come on these podcasts. This is why we do these things. If anyone today says, I feel empowered, I can take action here. I'm gonna add more vegetables. I'm gonna add more colors. I'm gonna go for a walk after my meals, ideally in nature. I'm gonna look at what brings me joy. Michelle (40:57) Yeah. Sarah Wilson (41:17) and include more of that. I'm gonna work on my boundaries, I'm gonna correct my nutrient deficiencies, and I'm gonna look at my microbiome. You will get so far, so far in your health. And that to me is just, it's so beautiful. Michelle (41:26) Yeah. yeah, for sure. mean, it's really empowerment. So, well, this is great. You shared so much amazing information. I could definitely keep talking to you because there's just so much that we can keep unpacking. But if people are interested in working with you, want to find out more about you, how can they find you? Sarah Wilson (41:53) Yeah, absolutely. Well, thank you. know I was, these are always such loaded conversations because we start and it's like, do we go here? Do we go here? So exactly. Michelle (42:00) I know. There's just a, a, branches out and it has, it starts to take a life of its own. And then I'm like, okay, well, we still can't keep going, going, going. at one point. Sarah Wilson (42:11) I know totally. Yeah, so I, as I said, for anyone listening in Canada, I own Advanced Women's Health. So we have clinics across Ontario and BC and we're expanding. I have a whole team of practitioners that do clinical rounds every day and I work with all the time. For those of you in the US, I do have courses where I train naturopathic doctors. So if you like this approach and you want people who are in the US and beyond. then you can always reach out to my team as well. Their email is just info at advancedwomenshealth .ca and they've got that list of practitioners. So in either situation, we can help you out. I also poke around on Instagram. I do not post on there as much as I should, but it's always a goal. And yeah, I'm just so happy to connect with the audience. Michelle (42:52) Amazing. Well, Dr. Wilson, this was very informative and I love the fact that you do so much research and this is based on like real data and real information and you really understand it. Your mind tends to work that way, which is awesome because you have to find a career where your mind is really able to absorb that information and then apply it. And it sounds like you found a perfect. career for what you do and you're passionate about it as well. Sarah Wilson (43:20) Thank you. Yeah, no, I'm so fortunate. I love what I do. And like, I'm so fortunate that I get to build a team of people that begrudgingly love my brain. They're always on calls because we meet every day. So our team of practitioners meets every day and they're always asking questions and I'll spin out on something and I'll be like, welcome to the Ted Talk. Sorry, that just happened. Michelle (43:31) No, it's very interesting. Amazing. That's great. Well, that's how you know you love it. That's how you know it. Sarah Wilson (43:44) Yes. Yeah, exactly. Exactly. Well, thank you so much for having me. It's been such a joy. yeah, I just I love sharing this information. I'm happy to come back and share more anytime. Michelle (43:55) Yes. So thank you so much for coming on.
In this episode, we review the high-yield topic of Clostridium difficile from the Infectious Disease section at Medbullets.com Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets Linkedin: https://www.linkedin.com/company/medbullets
Il n'existe pas de « dopage » par matière fécale reconnu officiellement dans le domaine médical ou sportif. Cependant, il y a des traitements et des thérapies liées aux transplantations de microbiote fécal (TMF), utilisées pour rétablir l'équilibre du microbiote intestinal chez des patients souffrant de maladies comme l'infection à Clostridium difficile. Or le microbiote intestinal a un impact significatif sur la santé générale, y compris sur le métabolisme, l'immunité et, potentiellement, la performance physique. Donc certaines théories suggèrent que la modulation du microbiote intestinal pourrait améliorer les performances physiques, mais ce domaine reste largement spéculatif et non validé pour l'amélioration directe de la performance sportive. Les recherches sur le lien entre microbiote et performance sportive sont encore en cours, mais elles ne concernent pas l'utilisation du microbiote comme forme de dopage. Parmi ces recherches,il faut citer celles récentes qui ont étudié une bactérie appelée Veillonella. Cette découverte a suscité un grand intérêt dans le domaine de la science du sport et de la médecine. Veillonella et la performance sportive :Les chercheurs ont découvert que les athlètes d'endurance, comme les coureurs de marathon, ont une concentration plus élevée de bactéries Veillonella dans leur microbiote intestinal par rapport à des personnes moins actives. Cette bactérie semble jouer un rôle dans le métabolisme de l'acide lactique, un sous-produit de l'effort intense qui est généralement associé à la fatigue musculaire. La Veillonella a la capacité de convertir l'acide lactique en propionate, un acide gras à chaîne courte. Le propionate est une source d'énergie pour le corps et pourrait, en théorie, améliorer les performances sportives en réduisant l'accumulation d'acide lactique dans les muscles, retardant ainsi la fatigue et permettant à l'athlète de maintenir un effort intense plus longtemps. Études sur la Veillonella :Dans une étude réalisée en 2019, les chercheurs ont transplanté cette bactérie chez des souris, et les résultats ont montré une amélioration significative de leur endurance. Cela a soulevé la question de savoir si cette bactérie pourrait être utilisée de manière bénéfique chez les athlètes humains pour améliorer les performances. Dopage à la matière fécale ?Bien qu'il soit encore prématuré de parler de "dopage" à la matière fécale, l'idée que la modification du microbiote intestinal puisse influencer les performances sportives est en train de prendre de l'ampleur. Si la Veillonella peut effectivement améliorer la performance en retardant la fatigue, il n'est pas exclu que des athlètes ou des équipes cherchent à l'exploiter, de manière éthique ou non, dans l'avenir. Cependant, cette forme d'optimisation biologique n'est pas encore officiellement classée comme du dopage, mais elle pourrait être surveillée par les autorités antidopage si les recherches continuent à démontrer un effet significatif sur la performance. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Your gut is home to an entire ecosystem of microorganisms that silently shape your digestion, immune function and overall health. Most of us barely think about it, but this hidden universe inside us plays a vital role in our well-being. I recently explored my own gut microbiome using Jona, an AI-powered platform that goes far beyond typical gut tests. Jona offers personalized insights based on cutting-edge research, showing how your microbiome could be impacting everything from inflammation to metabolic health. I was surprised to discover that my gut contains 246 different microorganisms, including the pathogen Clostridium perfringis. While that sounded alarming at first, Jona helped me understand that, in the context of my lifestyle — which includes raising livestock and spending a lot of time outdoors — it's not a cause for concern. More importantly, Jona highlighted that my gut's bacteria have powerful anti-inflammatory properties, which may explain why my CRP levels are consistently low. One of the most fascinating aspects of my results is how they align with my animal-based diet. Most of the probiotics in my system come from fermented dairy products like kefir, reflecting how my dietary choices have shaped the microorganisms living inside me. Jona's personalized approach even helped confirm why I sometimes experience discomfort with raw milk, revealing that my gut lacks certain lactose-digesting bacteria. If you're interested in gaining deeper insights into your own gut health, Jona could be a game-changer. The platform links your microbiome data with real scientific studies, offering actionable recommendations tailored to your lifestyle and health goals. Make sure to use code Michael50 for 50% off your own gut analysis and take control of your gut health. In this episode: 00:00:00 - Intro 00:00:43 - Sponsor Mention: OneSkin 00:01:20 - What is Jona AI? 00:02:40 - My Gut Microbiome Results 00:07:39 - Final Thoughts & Recommendations Learn more: For more in-depth information about Jona AI and how it can help you understand and optimize your gut health, visit the official site at Jona Health. Discover how advanced AI technology, combined with scientific research, can transform your approach to gut health and well-being.
All this talk about microbiome, gut flora, prebiotics, probiotics...what does it all mean, and how important is it to our health? Learn all this and ways to foster that perfect balance. Show Notes: https://bit.ly/47oumUj In this Episode:03:33 - Ways to Die in the Future - A Near Earth Asteroid08:03 - Recipe of the Week: Hummus09:52 - Understanding the Microbiome and its Role41:15 - A Diversified Microbiome45:45 - OutroMagnificent Microbes!As we continue our series about ways to slow our march toward the end of life, our topic this week is about our microbiome. You have probably heard of this term, but may wonder what it means and how it applies to you. Our gut microbiome are microbes, and their genetic material is found in our gastrointestinal tract. Bacteria in our gut affect everything from our digestion to our mental health. What does Our Microbiome do for Us?Marianne shares the evolution of our microbiome and how it develops diversity. This is important because different bacteria help us digest food, produce vitamins, increase absorption, helps our immunity, and prevent bad bacteria from taking over.Why is Balance Important?When something disrupts the balance, such as antibiotics, it can allow "opportunistic growth" of organisms such as Clostridium difficile (C. diff), a germ that causes diarrhea and colitis.How to Increase your Gut DiversityWe talk about several ways to foster diversity in your microbiome. Listen for several tips!Support the showGet show notes and resources at our website: every1dies.org. Facebook | Instagram | YouTube | mail@every1dies.org
Send us a textIn this FRIDAY 5 episode of The Autoimmune RESET, we dive into the lesser-known potential causes of multiple sclerosis (MS) that could provide new insights into managing and preventing this complex autoimmune disease. Join VJ as she explores five surprising factors that might contribute to MS, including vitamin B12 deficiency, aquaporin-4 cross-reactivity, Clostridium perfringens toxin, the shingles virus, and dairy sensitivity. Could these hidden triggers be playing a role in MS? Tune in to learn more about how understanding these factors might open new doors to relief and improved health. Plus, find out how you can take the next steps with a free introductory call at The Autoimmunity Nutritionist Clinic.Don't miss this enlightening episode—subscribe now and take charge of your health journey!Plus, don't miss a special announcement about my new program, The Inflammation Reset, designed to help you tackle inflammation at its source and reclaim your health. You can learn more here.Tune in to discover how to restore balance, reduce chronic inflammation, and optimise your well-being from the inside out.If you are ready for change, download your free copy of The Autoimmunity Recovery Plan here so you can get started.Or, if you prefer working together 1-2-1 or would like to explore functional testing, you can find all my services here. Thanks for listening! You can join The Autoimmune Forum on Facebook or find me on Instagram @theautoimmunitynutritionist.
Unfortunately, there simply isn't a one-size-fits-all treatment protocol for patients infected with Lyme disease and/or co-infections. This is why it's critical for physicians treating Lyme disease to invest time with patients, thoroughly understand their medical history, and closely monitor symptoms and treatment response. With that in mind, there are currently two different treatment approaches for Lyme disease. The Infectious Disease Society of America (IDSA) and the International Lyme and Associated Diseases Society (ILADS) have each published their own set of evidence-based treatment guidelines. IDSA guidelines recommend a short course of antibiotics, typically 14 to 30 days. IDSA argues that the Borrelia burgdorferi bacteria do not persist in a patient beyond this timeframe and that lingering symptoms are the result of an ongoing immune response and not an active infection. It also cites scientific evidence claiming treatments beyond 30 days are ineffective, unnecessary, and even dangerous. IDSA physicians will stop treatment after 30 days, even if symptoms remain. They advise an additional 30 days of treatment recommended for patients with Lyme arthritis. On the contrary, ILADS offers its own scientific data to show that a additional treatment with antibiotics is required to eradicate the bacteria. ILADS recognizes that a month of treatment may be sufficient for patients in the acute stage of Lyme disease, but in cases where the spirochete has disseminated and the disease has advanced, a 30-day treatment regimen is inadequate. ILADS guidelines recommend additional antibiotics until a patient's symptoms have been resolved. Treating Lyme disease in its advanced stage can be complicated based on the complexity of the organism itself, differences in each patient's immune system, the length of time infected, and the possible presence of other co-infections transmitted by the same tick. There are several choices in treating Lyme disease, which include oral, intravenous, and intramuscular antibiotic options. Other options may include sequential antibiotic therapy, higher doses of antibiotics, taking antibiotics for a longer period of time, a combination of antibiotics, retreatment, as well as diagnosing and treating co-infections. Some specific antibiotics used in treating Lyme disease are doxycycline, minocycline, amoxicillin, cefuroxime, azithromycin, and clarithromycin. Other tests include measures of blood counts, chemistries, liver function tests, ANA, dsDNA, RF, TSH, free T3, free T4, ESR may be helpful at ruling out other conditions. Referral to specialist might help to rule out other conditions. I find shared decision with my patient helpful. I also find follow-up helpful to assess my patient's response to treatment to rule out other conditions. There are additional protocols that may also aid in treating Lyme disease, such as avoiding alcohol, simple and processed sugars, exercising as tolerated, counseling for a Jarisch-Herxheimer reaction, managing symptoms, monitoring and reducing the risk of an adverse event, and reducing stress. However, there is a chance of side effects such as Clostridium difficile-associated diarrhea (CDAD). Probiotic have been prescribed with the hope of reducing the risk of developing CDAD.
What if a rusty nail poked your foot? You've probably heard by now that getting injured by any rusty object can lead to tetanus. Tetanus is caused by bacteria known as Clostridium tetani, which is commonly found in soil, dust, and animal feces – all ideal places for rusty objects to be found. Anyway, if this bacteria enters your body through the wound, you're in really serious problems... Random questions like these keep the most curious of us up at night so today's video will answer them! And if any of your most burning questions will be missed, then ask away down in the comments – we'll be sure to cover them next time! Other videos you might like: What If Dinosaurs Were Still Alive Today? • What If Dinosaurs Were Still Alive To... What If You Stopped Eating Sugar for 1 Week • What If You Stopped Eating Sugar for ... What If The Sun Went Out for Just One Day • What If The Sun Went Out for Just One... TIMESTAMPS: What happens if you drink too much water? 0:24 What happens when you swallow gum? 0:51 What can happen if you step on a rusty nail? 1:30 What if gravity suddenly got turned off? 2:26 What if all cats just disappeared? 3:01 What would happen if the Earth lost oxygen for 5 seconds? 3:37 What if the internet stopped working for one day? 4:11 What if you didn't wash your hair for a year? 4:56 What would happen if you ate 50 boiled eggs in one sitting? 5:39 What if the Earth started spinning twice as fast? 6:21 What if we all jumped at the same time? 7:19 What if we had no Moon? 7:51 #whatif #tetanus #earth Music by Epidemic Sound https://www.epidemicsound.com/ Subscribe to Bright Side : https://goo.gl/rQTJZz ---------------------------------------------------------------------------------------- Our Social Media: Facebook: / brightside Instagram: / brightgram 5-Minute Crafts Youtube: https://www.goo.gl/8JVmuC Photos: https://www.depositphotos.com East News ---------------------------------------------------------------------------------------- For more videos and articles visit: http://www.brightside.me/ Learn more about your ad choices. Visit megaphone.fm/adchoices
Not one of us are completely immune to an occasional episode of diarrhea. Whether you can trace it back to something you ate or an up tick in stress, liquid poop is not ideal. Kate and Megan are joined by a giant in the field of gastroenterology, Dr. Jessica Allegretti from Brigham & Women's Hospital in Boston, Massachusetts to do a deep dive discussion into diarrhea. Together, they discuss the various causes of diarrhea, from common infections and food intolerances to more chronic conditions like irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Dr. Allegretti offers valuable insights into the concerns surrounding Clostridium difficile (C. diff) infections and the complexities involved in diagnosing and treating recurrent cases. We also explore cutting-edge research of live biotherapeutic products (LBPs) and their promising role in the innovative area of fecal microbiota transplantation (FMT) with the guidance of this world-renowned expert. And, we couldn't discuss diarrhea without acknowledging the potential role of food, stress and the intricate relationship between our gut microbiome and our behaviors. Kate and Megan provide practical tips and tricks to the nutritional and behavioral management of this often times anxiety provoking symptom that leave all listeners feeling empowered with strategies when it comes to the runs. Whether you've had C.Diff, are managing IBS-D or just curious about this common symptom this episode is a must listen! Tune in for practical insights and valuable strategies to improve your well-being and gut health. Read more: Diagnosis and Management of Clostridioides difficile Infection in Patients with Inflammatory Bowel DiseaseYale Medicine: C. Diff Infection overviewApproach to the Patient with Diarrhea and MalabsorptionLow FODMAP toolsDiaphragmatic breathing (video by Dr. Megan Riehl)Learn more about Kate and Dr. Riehl:Website: www.katescarlata.com and www.drriehl.comInstagram: @katescarlata @drriehl and @theguthealthpodcastOrder Kate and Dr. Riehl's book, Mind Your Gut: The Science-Based, Whole-body Guide to Living Well with IBS. The information included in this podcast is not a substitute for professional medical advice, examination, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider before starting any new treatment or making changes to existing treatment.
Dr. Don and Professor Ben talk about the risks from vacuum packaged cheddar cheese stored for 24 hours at room temperature. Dr. Don - not risky
In this episode, hosts Drs. Temara Hajjat and Peter Lu talk to Dr. Maria Oliva-Hemker about diagnosing and managing Clostridioides difficile (C. diff) in children who have inflammatory bowel disease (IBD). Dr. Oliva-Hemker is the Director of the Division of Pediatric Gastroenterology, Hepatology, and Nutrition and the Stermer Family Professor for Pediatric IBD at the Johns Hopkins University School of Medicine. She is also the Vice Dean for Faculty and the Mary Wallace Stanton Professor for Faculty Affairs. Learning Objectives:Learn how to diagnose Clostridioides difficile, particularly when there is concern about a new IBD diagnosis.Learn how to manage C. diff infection in a patient with known IBD.Learn how to manage recurrent and refractory C. diff infection in a patient with IBD.Link: Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)AGA Clinical Practice Guideline on Fecal Microbiota–Based Therapies for Select Gastrointestinal DiseasesACG Clinical Guidelines: Prevention, Diagnosis, and Treatment of Clostridioides difficile InfectionsSupport the Show.This episode is eligible for CME credit! Once you have listened to the episode, click this link to claim your credit. Credit is available to NASPGHAN members (if you are not a member, you should probably sign up). And thank you to the NASPGHAN Professional Education Committee for their review!As always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and guests and are subject to change over time with advances in the field.Check out our merch website!Follow us on Twitter, Facebook and Instagram for all the latest news and upcoming episodes.Click here to support the show.
Clostridium difficile,A.K.A. C DIFF , is an intestinal infection caused by using antibiotics for other infections, eating foods containing antibiotics or transmission by contact with the bacteria in contaminated settings such as hospitals.500,000 people in the USA get it every year and hundreds of thousands more worldwide. While 30,000 people (mostly seniors and children die each year) the pain and suffering for all who have it is just horrible! We will discuss the latest NATURAL ways to prevent recurrence and stop your suffering permanently and completely once and for all!
Clostridium difficile,A.K.A. C DIFF , is an intestinal infection caused by using antibiotics for other infections, eating foods containing antibiotics or transmission by contact with the bacteria in contaminated settings such as hospitals.500,000 people in the USA get it every year and hundreds of thousands more worldwide. While 30,000 people (mostly seniors and children die each year) the pain and suffering for all who have it is just horrible! We will discuss the latest NATURAL ways to prevent recurrence and stop your suffering permanently and completely once and for all!
Joseph is a 14 year-old, generally well and up-to-date with health maintenance, who presents for a sick with a 36 h hx of gradual onset nausea, vomiting and loose stools, reporting “I'm not sure how many times I threw up or had diarrhea.” He last vomited about 4 h ago, last stool was around 2 h ago, reported as yellow brown in color, small volume and without blood. He has been tolerating a sips of clear liquids for the past 3 h and voided a small amount around 2 h ago. Joesph reports that he is on the wresting team at his high school and that, “For the past week, one guy after another got this same thing.” VS are within normal limits and his mucous membranes are slightly dry. The most likely cause of Joseph's clinical condition is: A. Staphylococcal food poisoningB. Clostridium difficile (C. diff) enteritisC. Viral gastroenteritisD. Gastric ulcer Visit fhea.com to learn more!
Clostridioides difficile, formerly known as Clostridium difficile, is an anaerobic, spore-forming bacillus that causes a serious bacterial infection in the colon. While healthcare-associated infections have declined in recent years, C. diff remains one of the most common healthcare associated infections in the United States. Learn more about C. diff infection (CDI) in this episode, including: Pathophysiology of CDI Who is most at risk for CDI Complications of CDI Signs and symptoms, and when to suspect your patient has C. diff Important assessments for a patient with CDI Tests utilized to diagnose a patient or evaluate complications Key treatments for CDI, including an explanation of enhanced or “special” contact precautions The main things to teach your patient and their visitors about CDI ___________________ Full Transcript - Read the article and view references. FREE CLASS - If all you've heard are nursing school horror stories, then you need this class! Join me in this on-demand session where I dispel all those nursing school myths and show you that YES...you can thrive in nursing school without it taking over your life! Study Sesh - Change the way you study with this private podcast that includes dynamic audio formats that help you review and test your recall of important nursing concepts on-the-go. Free yourself from your desk with Study Sesh! Med Surg Solution - Are you looking for a more effective way to learn Med Surg? Enroll in Med Surg Solution and get lessons on 57 key topics and out-of-this-world study guides.
Multiple sclerosis (MS) is the most common, though complex, disabling neurological disease in young adults, starting as early as age 20. Worldwide, there are over 2.8 million people with MS, and in the United States, nearly 1 million. According to National Multiple Sclerosis Society multiple sclerosis is a disease that impacts the brain, spinal cord, and optic nerves, which make up the central nervous system and controls our muscle functions. While the exact cause of MS is still not clear we do know that “something” triggers the immune system to attack the central nervous system. Researchers may now have found this “trigger”! Gut dysbiosis is common in MS, but until now no specific causative species was identified as a possible “trigger”. Now several studies have been published strongly suggesting Clostridium perfringens strains (Type B) in the gut are biologically plausible pathogens in MS that trigger inflammatory demyelination of the nerves! The strains of this opportunistic pathogen are known to secrete over 20 identified toxins. We will discuss this amazing breakthrough and offer a safe and REAL answer to this horrible disease.
Multiple sclerosis (MS) is the most common, though complex, disabling neurological disease in young adults, starting as early as age 20. Worldwide, there are over 2.8 million people with MS, and in the United States, nearly 1 million. According to National Multiple Sclerosis Society multiple sclerosis is a disease that impacts the brain, spinal cord, and optic nerves, which make up the central nervous system and controls our muscle functions. While the exact cause of MS is still not clear we do know that “something” triggers the immune system to attack the central nervous system. Researchers may now have found this “trigger”! Gut dysbiosis is common in MS, but until now no specific causative species was identified as a possible “trigger”. Now several studies have been published strongly suggesting Clostridium perfringens strains (Type B) in the gut are biologically plausible pathogens in MS that trigger inflammatory demyelination of the nerves! The strains of this opportunistic pathogen are known to secrete over 20 identified toxins. We will discuss this amazing breakthrough and offer a safe and REAL answer to this horrible disease.
Dr. Don and Professor Ben talk about the risks of leaving boiled chunks of Yukon gold potatoes at room temperature overnight. Dr. Don - risky ☣️ Professor Ben - risky ☣️ J. Kenji López-Alt James Neal (ice hockey) - Wikipedia Last night I followed the beginning of my extra-crispy roast potato recipe (I boiled chunks of Yukon golds in water with salt and a pinch… | Instagram Large Outbreak of Botulism: The Hazardous Baked Potato | The Journal of Infectious Diseases | Oxford Academic Restaurant-Associated Type a Botulism: Transmission by Potato Salad | American Journal of Epidemiology | Oxford Academic Combined effect of water activity and pH on inhibition of toxin production by Clostridium botulinum in cooked, vacuum-packed potatoes | Applied and Environmental Microbiology Presence and Significance of Bacillus cereus in Dehydrated Potato Products - ScienceDirect Influence of temperature shifts on survival, growth, and toxin production by psychrotrophic and mesophilic strains of Bacillus cereus in potatoes and chicken gravy - ScienceDirect Presence and Growth of Bacillus cereus in Dehydrated Potato Flakes and Hot-Held, Ready-to-Eat Potato Products Purchased in New Zealand - ScienceDirect 154. Michael Scott Bacon Method — Risky or Not?
Dr. Don and Professor Ben talk about the risks of eating a smelly hamburger left in car for three days. Dr. Don - risky ☣️ Professor Ben - risky ☣️ All-American Cheeseburger - Nearby For Delivery or Pick Up | Buffalo Wild Wings McDonald's Burger Survives 20 Years and Still Looks Fresh off the Grill - Interesting Engineering Control of Clostridium perfringens in Cooked Ground Beef by Carvacrol, Cinnamaldehyde, Thymol, or Oregano Oil during Chilling - ScienceDirect
Christian Lillis, Co-Founder and CEO of the Peggy Lillis Foundation is a patient advocate in the fight against C. diff infection. Clostridium difficile is an opportunistic infection of the gut that often occurs after taking antibiotics and can lead to life-threatening complications. Christian shares his personal story of losing his mother to C. diff and highlights the progress made in raising awareness and the development of new treatments for the infection. The Peggy Lillis Foundation emphasizes the importance of patient voices in shaping infectious disease policies and research and the need for community support to fight C. diff and other preventable infectious diseases. Christian explains, "Last time we did our most recent C. diff awareness month campaign in November, it was our most successful one yet. We reached around 23 million people through a mix of earned, print, video, and podcast media and a strong social media campaign. We also had it bolstered by media partnerships with Contagion Live and Pharmacy Times. As part of our programming for the month, we held a virtual town hall, and about 200 people attended. More than half of them were C. diff patients, survivors, and family members." "Other progress was at the end of 2022, and then in early 2023, two new therapies. Technically, they are classified as preventative by the FDA, but they are basically microbiome restoration therapies. As I said earlier, when you take antibiotics, there can be other causes. Still, when your gut microbiome, gut bacteria, and viruses get out of whack or depleted, you become very vulnerable to C. diff. And a reason why people struggle to get over C. diff is because their gut microbiome remains degraded. So these new two therapies, one is done by enema, one is given by capsule over several days, it's a really huge change for people who are battling recurrent C. diff." #CDiff #PeggyLillisFoundation #ClostridiumDifficile #CDifficile #PatientAdvocacy #CdiffAwarenessMonth cdiff.org Download the transcript here
Christian Lillis, Co-Founder and CEO of the Peggy Lillis Foundation is a patient advocate in the fight against C. diff infection. Clostridium difficile is an opportunistic infection of the gut that often occurs after taking antibiotics and can lead to life-threatening complications. Christian shares his personal story of losing his mother to C. diff and highlights the progress made in raising awareness and the development of new treatments for the infection. The Peggy Lillis Foundation emphasizes the importance of patient voices in shaping infectious disease policies and research and the need for community support to fight C. diff and other preventable infectious diseases. Christian explains, "Last time we did our most recent C. diff awareness month campaign in November, it was our most successful one yet. We reached around 23 million people through a mix of earned, print, video, and podcast media and a strong social media campaign. We also had it bolstered by media partnerships with Contagion Live and Pharmacy Times. As part of our programming for the month, we held a virtual town hall, and about 200 people attended. More than half of them were C. diff patients, survivors, and family members." "Other progress was at the end of 2022, and then in early 2023, two new therapies. Technically, they are classified as preventative by the FDA, but they are basically microbiome restoration therapies. As I said earlier, when you take antibiotics, there can be other causes. Still, when your gut microbiome, gut bacteria, and viruses get out of whack or depleted, you become very vulnerable to C. diff. And a reason why people struggle to get over C. diff is because their gut microbiome remains degraded. So these new two therapies, one is done by enema, one is given by capsule over several days, it's a really huge change for people who are battling recurrent C. diff." #CDiff #PeggyLillisFoundation #ClostridiumDifficile #CDifficile #PatientAdvocacy #CdiffAwarenessMonth cdiff.org Listen to the podcast here
ASCO: You're listening to a podcast from Cancer.Net. This cancer information website is produced by the American Society of Clinical Oncology, known as ASCO, the voice of the world's oncology professionals. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guests' statements on this podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Cancer research discussed in this podcast is ongoing, so data described here may change as research progresses. In this Meaningful Conversations podcast, Dr. Karan Jatwani talks to Dr. Amy Case about what people with cancer should know about hospice care, including the difference between palliative and supportive care and hospice care, who is eligible to enroll in hospice care, and the types of support available for people receiving hospice care and their family and caregivers. Meaningful Conversations is a Cancer.Net blog and podcast series that describes the important discussions people may need to have with their providers, caregivers, and loved ones during cancer and offers ways to help navigate these conversations. Dr. Jatwani is a Medical Oncology Fellow at Roswell Park Comprehensive Cancer Center. Dr. Case is the Lee Foundation Endowed Chair of the Department of Palliative and Supportive Care at Roswell Park Comprehensive Cancer Center, and Professor of Medicine at the Jacobs School of Medicine and Biomedical Sciences of the University at Buffalo. View disclosures for Dr. Jatwani and Dr. Case at Cancer.Net. Dr. Jatwani: Hi, everyone. My name is Karan Jatwani. I'm one of the 3-year fellows at Roswell Park Comprehensive Cancer Center. I have finished my palliative care fellowship from Memorial Sloan Kettering Cancer Center. And I am interested in the integration of oncology as well as palliative care, and that is where I envision my future career to be. And it's my pleasure to be involved in a podcast with Cancer.Net and looking forward to it. Dr. Case: Hello. My name is Amy Case, and I'm the chair of the Department of Supportive and Palliative Care here at Roswell Park Comprehensive Cancer Center, and we're in Buffalo, New York. So I appreciate being invited to speak today. And we also have a fellowship that we run here and a pretty comprehensive department with 8 divisions that include palliative, social work, psychiatry, psychology, spiritual care, bioethics, and geriatrics, and also employee resilience. So we have a lot of kind of passion projects we work on in our supportive care department. Dr. Jatwani: Thank you so much, Dr. Case, for joining us today. I think I've always admired your work. And just to start off, just for our listeners and our audience, if you can just give us a brief idea of what palliative care is, I think that would be the best segue to enhance the discussion. Dr. Jatwani: So “to palliate” means to make feel better. And when I talk to patients about what it is that we do, I talk about how we take care of the whole person, which includes the physical symptom management, the emotional support, which could include psychiatry, psychology, or social work support of the emotional piece. And then also the spiritual support, which often we work as a team. In order to be palliative care, you actually need to be a team. It can't just be one physician, for example, doing palliative. You need to work as a team. So generally, a core team consists of a physician, a nurse, a chaplain, a spiritual care professional, and a social worker at its core. But sometimes it can be a nurse practitioner providing that or other specialists helping on that team. Dr. Jatwani: I think one of the key questions that always arise with the patients is, as soon as you talk about palliative care, patients start equating it to death. How do you make sure that the patients you're interacting with, how do you differentiate it with them, and how do you relieve that anxiety whenever the patient hears “palliative care”? Dr. Case: So no matter what you call the work that we do, there will always be a stigma. So if we change the name to yellow banana, people would be afraid of yellow bananas, right? So I think that the word hospice has-- I joke that it's kind of like a 4-letter word type of situation. We call it “the H word.” Sometimes patients are really fearful to hear that word. And even now, palliative has adopted this stigma. So generally, what I do is I kind of say that it's focused on quality of life. The main goal is to help people feel better, live a better quality of life, to get through their cancer treatments. And I also educate them that people who receive palliative care tend to have better outcomes. Patient-reported outcome metrics are better. So patients often have a prolonged survival. They may be able to tolerate their cancer treatment better and get through those treatments. And that generally, I would say, is something that they're happy to hear. That's something that they're usually, "Yeah, sign me up for that." When we start with somebody-- we spend an hour with every patient for a new visit. When I start with them, they're really skeptical. Oftentimes, they're looking at me mistrustfully, like, "What is this?" And by the end of the visit, they say, "Where has this been from the beginning of my cancer journey? And why am I only getting this now? This was the best interaction I've had at this organization." And it's because we give them kind of what we call a “wrap-around care,” which is almost like a big hug. We use a lot of skills that include empathy. And with our communication, we often spend a lot of time listening. And I think people really walk out feeling heard. Even if you can't solve it or cure it, you can discuss things that can just make them feel that you were there for them and you listened. And that is very powerful. Dr. Jatwani: I 100% agree. I mean, that has been my sort of experience as well during my fellowship. I took a lot of those learnings with me when I see my patients. But also, I think coming from an oncology standpoint, I can definitely now understand that I have been at fault when I have not given that palliative blanket that you were talking about at different times. And so my question is, when can patients ask for palliative care? And we'll discuss “the H word,” as you mentioned at the beginning. So we'll discuss with that as well. But when should patients undergoing cancer treatment, when should they ask for involvement of palliative care, or they should advocate for themselves or even the caregivers should advocate? Dr. Case: Yeah. So I think that generally, palliative care, the beauty of palliative care is that it doesn't really have a time limit. Someone can ask for it anytime. And often, we encourage people right from the beginning. So there's people who may be looking for that extra added support right from the beginning. And so we usually encourage oncologists and the oncology teams to start those discussions themselves. Dr. Jatwani: And I think at this point of time, I would like to definitely ask you. I think you mentioned “the H word” in the beginning. So can we discuss a little bit more about what is hospice care? Dr. Case: So palliative care is provided on a trajectory. So it can be provided anytime, even for survivors, for people who are earlier in their diagnosis. But hospice has a timeline on it because it's actually a Medicare benefit that it's like almost like an insurance benefit that kicks in, but the government pays for the patient's care. And so in order to enroll or sign up for hospice, a patient has to have certain criteria in order to meet that. In order to get those things paid for. And so hospices have to—generally, it's when a patient has a life expectancy of 6 months or less, and they have decided that the cancer treatment, meaning chemotherapy, radiation in most cases, immunotherapy, the burden of that is higher than the benefit. Most of the patients who see us in palliative are still getting their cancer treatment, and we're helping them walk the journey with them through their treatment, helping them feel better, starting those conversations. And then we do something called a transition to hospice. So many of the patients we see in palliative end up transitioning to hospice. How is palliative care different than hospice? How is hospice different than palliative care? They're very similar. The philosophy of care and the way it's provided is almost exact, meaning that it's a team-based approach made up of physical, emotional, and spiritual support for the patient provided by a team. Although in palliative care, many times that's done in a clinic or an inpatient setting. There are home palliative programs that exist. We have one here at Roswell as well. But hospice, 80% of the time, is done at home. Because generally, when people prefer to pass away and we talk to them, where do they want to be at the end of their life? I'd say 95% of people do want to be at home if that's feasible. The biggest barrier that they are worried about dying at home is that they worry about being a burden on their loved ones. And so that's the way I frame those discussions, is that I ask them about what are the things that they're hoping for. What are the things that they're worried about? And when I find out, inevitably, like I said, it's probably the number 1 fear of people to be a burden on their loved ones. It's this wonderful thing that can reduce burden on family to help care for you and have you be at peace in the place that you wish to be. Dr. Jatwani: I 100% agree. I think you framed it perfectly that if the discussions-- I think, as you said, they should happen at the right time point. And the other thing is I think they should happen often. They should not happen only once. They should happen at every juncture of time when the cancer care has sort of transitioned into going into the more risk and less benefit window. And that's a spectrum, as you mentioned. It does not have to happen only once, and the provider feels, “OK, I've done that discussion. Now I don't have to do it again.” Dr. Case: It's a journey. Dr. Jatwani: It's a journey, yes. Dr. Case: I think we always talk about a journey and that advanced care planning does not happen, excuse me, just once in the trajectory. It happens over multiple time points. And I call it “loosening the lid,” where the lid is often on really tight. There's maybe often mistrust of the health care system. People are really scared. And you really need to give them that emotional support. And that's why palliative is so beautiful because we provide them that wrap-around hug when they're feeling at their most vulnerable. And then when they have comfort with us, then it's much easier to discuss these really tough topics. And I think establishing rapport, getting to know them as a human being and who they are is extremely important. So, for example, my style is to start any medical visit with a social interaction and asking them about themselves socially. I say, “Let's put the cancer aside. I want you to tell me about you. Tell me about your family. Tell me about the things that you enjoy doing for fun.” And they often laugh because they want to talk just about the cancer, right? They say, “I don't have fun anymore.” And then I try to ask them about the things they did before they had cancer. And you see them light up, and you see the rapport being built, and you see the trust. And once you have those types of relationships, these discussions become much easier. Dr. Jatwani: I agree. So just to transition a little bit more about hospice care, I think you talked about that this hospice care is a Medicare benefit. Can you tell our audience, is it only at home or is it available inpatient as well? And can you speak a little bit about that? Dr. Case: Sure. So I mentioned before that generally, the majority of hospice care is preferred to be in the home, and really taking care of someone at the end of life actually can be less scary when you have the support of hospice. And so anyone who's in the hospital where a discussion is had and then advanced care planning is done, and they say, “You know what? I don't want to end up being on a ventilator. I'm going to elect to be a, “do not resuscitate or allow natural death.'" If that happens, I actually think it's almost imperative for hospice to also be consulted and offered. Because if you send someone home that is a “do not resuscitate” without those family support in place, the family will struggle. And so I think that it goes hand in hand. So dying at home goes hand in hand with having hospice in place. End of story. You need to have those supports in place. I do not think it will work out well for the family if you do not. And so there are rare circumstances where some physicians provide that support or home palliative can provide that support. But hospice really is the gold standard. So I'd say most of it is in the home. But once someone enrolls in hospice, there is caveats where if a patient is having uncontrolled symptoms that are not managed by the nurses in the home and the physicians by phone or by home visit, that the patient may be able to be brought in to an inpatient hospice unit or a hospital. They can unelect—to come off of, or unenroll—in hospice. For example, they change their mind. They decide, oh, they fall they break a hip, OK? And hospice is not going to fund a non-cancer-related hip fracture repair. So they would have to unenroll from that Medicare benefit, hospice Medicare benefit, and enroll in a different part of their insurance. And it's very easy to enroll and unenroll. And so there are different parts of that Medicare benefit that pay for different things. And so if somebody gets a hip fracture, it doesn't mean they have to not have it repaired. I mean, so you adjust and unenroll them from hospice, get the hip repaired, and then enroll them back in the hospice. And so those types of things can totally be done. It doesn't mean the patient can never come back to the hospital. It doesn't mean they can't change their mind. It doesn't mean that if, say, they get pneumonia, that they can't have their pneumonia treated. So simple infections, like Clostridium difficile (C. diff), pneumonia, the hospice actually gives antibiotics. They manage a lot of medical treatments like anticoagulation and things like that. So there are, depending on the hospice, leeway with some of those medical treatments. For example, total parenteral nutrition (TPN), percutaneous endoscopic gastrostomy (PEG) tubes, some of those things can be managed in hospice. However, if a PEG tube or a TPN is causing more burden, they will continue to have those discussions about, is this treatment in the best interest of comfort and quality of life? And so that's generally the philosophy of care. And so, yes, they can be inpatient. There can be coming back to the hospital. And there are hospice inpatient units kind of all over the country. Some cities may not have hospice inpatient units, and they have other things like something called a “comfort home,” where comfort homes are depending on the area, the region that you live. Comfort homes exist in some cities where they're run by volunteers, and a patient may not be able to be at home, but they can go to a comfort home. Sometimes hospice can be provided in an assisted living where a patient's home is actually not home, it's in a facility or it can be provided in a nursing home. However, I think there's a misperception that hospice pays for the room and board of those places, and that is actually not true. So if someone needs a facility to live, then the family or the patient is on the hook, unfortunately, for the room and board. And so a lot of times, that delays discharge. So, for example, family does not want to take that patient home. They are not able to do that. The patient then needs a facility with hospice. The assumption is the hospice will pick up the bill of the facility. So that does not happen. But hospice covers all of the costs related to the care of the patient that's related to their hospice diagnosis. Dr. Jatwani: For patients who are living alone, who are in the elderly population, who are undergoing cancer-directed treatments, for those patients, is hospice an option? If it is, because that is always a challenging area that we face, how do you deal with those patients? Dr. Case: That's very challenging. Generally, we would call on social work and some of those specialties to help us figure out a support care network for that patient. And so often, you can actually recruit folks to take shifts coming in and checking on that patient. And so, yes, you can have hospice care for a patient who has a care-- generally, you need to have a caregiver who is around for that patient. Ideally, in an ideal world, there's somebody with that patient 24/7 when the patient is really ill. If the patient is pretty functional and they're on hospice, walking around, there may be some hours out of the day where they may not need someone with them. And really, we kind of determine that on a case-by-case basis. I would say it's not a door-shut situation that if someone lives alone, they could never have hospice. I would not say that. But in an ideal world, we do need to recruit someone to be there with the patient. If someone has absolutely no one to be there with them during hours during the day, which I think is pretty rare, then generally, if the person is too ill to stay home alone, it'll be a conversation that you have with that patient that they may be moved to a higher level of care, meaning that they may need a skilled nursing facility with hospice on board coming in and checking on them. That's their new home, or they may need an assisted living. And there are some facilities that provide their own hospice, meaning that if you go to that facility, they have a team that's built into that facility that provides them the end-of-life care at the facility, and they don't allow in external hospices. So it kind of depends on your area where you're practicing and asking those questions as, "Do you have an external hospice or do you provide hospice services internally?" And those are questions I often steer patients to ask. Dr. Jatwani: Just some parting thoughts on in terms of, as you said, hospice has a very selective criteria. And some patients might say, "How can you prognosticate me for living less than 6 months?" That's a challenging question that we often get. And I think you have answered it partly, that it's enroll “on and off switch” kind of situation. But what if a patient starts feeling much, much better on hospice and they feel that they want to come back and get cancer-directed treatment, how does palliative care and hospice care come into that domain? Dr. Case: Prognostication, when a physician is asked to prognosticate a patient, we call it “the art of prognostication” because you can't always look it up in a textbook and get the right answer. And what one physician may determine is a prognosis for a patient, another one may give a different one. Because we look at the same things, but a lot of times, there's a clinician estimate that comes into it that is really one of those, you put a bunch of facts together and you come up with what we call an estimate. And so sometimes, we may be correct. Sometimes, we may underestimate or we may overestimate. If a patient enrolls in hospice and they, for example, are doing a lot better, they're outliving the 6 months, the hospice programs often reevaluate those patients, and they do allow folks to stay enrolled with hospice care sometimes quite longer than the 6 months. Sometimes, people are on hospice a year or even longer. What they need to document is that the patient has an ongoing need where they need the multi-disciplinary team supportive care. And so as long as you meet certain criteria, and generally, the criteria are often that they have the continuing progression of the cancer or whatever the other medical illness is, the disease itself, and advancing illness, whether that be chronic obstructive pulmonary disease (COPD), congestive heart failure (CHF). It doesn't have to just be cancer. And you need to also have often a documentation of potentially continued functional decline or functional impairment. So prognosis is tied hand in hand with functional status. And so we don't just look at the computed tomography (CT) scan when we're determining prognosis. We look at nutritional. We look at weight loss. We look at appetite. We look at functional status and comorbidities. And there's a lot of other things that go into that, not just, “Is the tumor growing on the scan, yes or no?” So it's really important to look at a wide array of things when we're determining prognosis. Dr. Jatwani: Yes. And I think that sort of I just wanted to give our patients some idea of how we determine. I know there are a lot, many things that we have not covered, and we haven't even touched the expertise of Dr. Case, which we hope to do that in the future. And from my end, these are the questions that I had. And we hope to reconnect soon Dr. Case, and get some more insights into other aspects of palliative care, which you have done a lot of wonderful work in. Dr. Case: Thanks, Dr. Jatwani. ASCO: Thank you, Dr. Jatwani and Dr. Case. Find more podcasts and blog posts in the Meaningful Conversations series at www.cancer.net/meaningfulconversations. Cancer.Net Podcasts feature trusted, timely, and compassionate information for people with cancer, survivors, and their families and loved ones. Subscribe wherever you listen to podcasts for expert information and tips on coping with cancer, recaps of the latest research advances, and thoughtful discussions on cancer care. And check out other ASCO Podcasts to hear the latest interviews and insights from thought leaders, innovators, experts, and pioneers in oncology. Cancer.Net is supported by Conquer Cancer, the ASCO Foundation, which funds lifesaving research for every type of cancer, helping people with cancer everywhere. To help fund Cancer.Net and programs like it, donate at CONQUER.ORG/Donate.
Neilanjan Nandi, MD, FACP is an Associate Professor of Clinical Medicine at Penn Presbyterian Medical Center at the University of Pennsylvania. Dr. Nandi's practice focuses on the management of Inflammatory Bowel Disease (IBD, eg, Crohn's disease, Ulcerative Colitis) and recurrent Clostridium difficile infection via Fecal Microbiota Transplantation (FMT). Dr. Nandi serves on the executive council of the Philadelphia Crohn's & Colitis Foundation (CCF), the medical advisory board of the United Ostomy Associates of America (UOAA), coordinates outreach on the American College of Gastroenterology Patient Care Committee and is a founding board member of the South Asian IBD Alliance (SAIA). He also regularly peer reviews research publications and serves on the social media editorial board for the premier journals 'Inflammatory Bowel Diseases' and 'Crohn's & Colitis 360.' His research has focused on studying conditions co-morbid to IBD quality of care such as characterizing the management and consequences of iron deficiency anemia and non-alcoholic fatty liver disease in IBD patients. He has a particular interest in the diagnosis and management of refractory Clostridioides difficile infection and the application of fecal microbiota transplantation in C difficile. Dr. Nandi has helped conduct a number of clinical trials of stool derived microbiome therapies. He has also authored numerous book chapters on the diagnosis and management of various viral, parasitic, mycobacterial and bacterial infections of the GI tract. Dr. Nandi's fervor for clinical education has been recognized with multiple teaching awards including the 2023 Sidney Cohen Faculty Teacher of the Year for the Gastroenterology & Hepatology division of the University of Pennsylvania. He was honored as the 2019 Physician Hero by the Philadelphia/Delaware Valley Crohn's and Colitis Foundation at their annual Take Steps for Crohn's & Colitis event and wields digital & social media platforms to amplify education, outreach & advocacy in IBD to clinicians and patients. He was also awarded the Philadelphia CCF's Chairman's Citation in 2022. He is the regular host of an academic podcast : ‘GI Insights: IBD Crosstalk' which features high yield, evidence based medicine discussions with guests from different interdisciplinary fields critical to providing comprehensive IBD care. Dr. Nandi's passions include fitness, cooking, virtual reality gaming, reading and dancing. Follow him on social @fitwitmd.
Dr. Helveston's new book tells the history of the Clostridium botulinum, a bacterium that was discovered and researched as a poison and how it came to be Botox, with multiple medical applications and a household word in the beauty industry. As an ophthalmologist, Dr. Helveston worked with Alan Scott who is credited with developing and manufacturing Botox although, as you'll hear in the episode, his rewards were more advancing science and having fun rather than making money. It's a fascinating tale of a remarkable person and his dedication to a useful toxin.Eugene Helveson's website:https://eugenehelveston.com/Thoughts? Comments? Potshots? Contact the show at:https://booksshowstunes.discreetguide.com/contact/Sponsored by Discreet Guide Training:https://training.discreetguide.com/Follow or like us on podomatic.com (it raises our visibility :)https://www.podomatic.com/podcasts/books-shows-tunes-mad-actsSupport us on Patreon:https://www.patreon.com/discreetguideJennifer on Post.News:@JenCrittendenJennifer on XTwitter:@DiscreetGuideJennifer on LinkedIn:https://www.linkedin.com/in/jenniferkcrittenden/
We share how to keep scours from affecting your herd this calving season. Red Angus enthusiasts, step up, we introduce you to Wasem Red Angus. News, Markets and more on this all new episode of The Ranch It Up Radio Show. Join Jeff 'Tigger' Erhardt, the Boss Lady Rebecca Wanner aka 'BEC', and our crew as we bring you the latest in markets, news, and Western entertainment on this all-new episode of the Ranch It Up Radio Show. Be sure to subscribe on your favorite podcasting app or on the Ranch It Up Radio Show YouTube Channel. EPISODE 168 DETAILS Everyone has their breed of choice. For whatever reason and experiences we've had, has led many of us picking certain breeds over others. Today we explore the philosophy and goals around Wasem Red Angus. Calving season is getting ready to start for many producers and for some others it is still a ways away yet. Regardless, we need to get a jump on scours and make sure each and every calf that hits the ground has the best chance of survival. A simple solution… FARMATAN from Imogene Ingredients. As always we have the latest market reports and recaps from Kirk Donsbach with Stone X Financial, Inc. along with news and updates you need to hear. It's all covered on this brand new episode of The Ranch It Up Radio Show! WASEM RED ANGUS The Wasem family started ranching in 2004 in Halliday, North Dakota with a small herd of commercial Red Angus and Simmental cows. They decided to get into the registered Red Angus business and held their first bull sale in 2012. Each year they keep back the best registered heifers to expand the registered herd and to improve our genetics. They strive to offer cattle with power and performance through balanced EPD's and phenotype. Disposition is a must in the herd. They are proud to be selling Red Angus Bulls in North Dakota. They welcome you out any time to look at cattle. Family Business Here at Wasem Red Angus, we are truly a family operation. Each one of us has a job on the ranch and work together to make the operation a success. Chris is in charge of many of the daily tasks, including feeding, planting, and harvesting. Jolyn works on record-keeping and marketing. Kacee is the number 2 cook in the house, quickly making her way to the top. Braelyn is the one who makes us all laugh. There are many days on the ranch, we need a good laugh! The girls have been a huge asset working cattle the past few years, they are learning about low-stress livestock handling, as well as becoming good horsemen. We wouldn't be able to get everything done without the help of family, friends, and neighbors throughout the year and we are grateful for those relationships. Customer Service Customer service is really important to us. The relationships we build don't end the day of the sale. We stand behind the Red Angus Bulls we sell, and your happiness is important! WHAT CAUSES SCOURS IN BEEF CATTLE/CALVES Clostridia-Enterotoxemia The most common form of Clostridium in cattle is caused by Clostridia perfringens. The gram-positive bacteria are a challenge due to its ability to form spores and lay dormant for long-periods of time. The bacteria reproduce by releasing spores into its environment (soil, feed, manure). The spores can even lay dormant in the animal's intestine until opportunity presents itself. Infection takes place either through ingestion of spores or through an open wound. The most severe cases happen within the first month of a calf's life, and can result in sudden death. Clinical Signs • Diarrhea - Bloody, Mucus Present, Bubbly • Dehydrated • Bloat • Blindness Prevention/Treatment: Prevention can be difficult due to the Clostridia spores being extremely durable and present almost everywhere. Complete cleanout and disinfection between calves is helpful, but not always effective. A good vaccination program will reduce clinical disease. The best method is to develop good gut health and the immune system of the calf. Farmatan has been shown to strengthen the intestinal wall, helping to prevent infection from taking hold. Coccidiosis Cattle are host to numerous species of Coccidia, a single-celled protozoal parasite. Infection and clinical symptoms can happen any time during a calf's life, with the most severe reaction usually occurring between 3-6 weeks of age. The life-cycle of coccidia requires time to infect the intestine causing destruction of the mucosal and epithelial lining. The oocytes mature outside the host in warm, moist environments before being consumed, causing infection of a new host. Clinical Signs • Diarrhea - Watery, Bloody • Depression • Weight Loss Prevention/Treatment: Prevention of Coccidiosis is possible by keeping young calves separate from older animals, providing clean water and feed, and dry conditions. Isolation of infected animals is key to preventing transmission. Keeping the pen dry is the most important step a farmer/rancher can take in preventing Coccidiosis. Treatment can have a good impact on reducing secondary disease, and speeding up recovery time. Farmatan has been shown to disrupt the reproductive cycle of Coccidia; and may help strengthen the intestinal wall to prevent infection, in both the cow and calf. Coronavirus Bovine Coronavirus is a ubiquitous, envelope-viral disease, causing respiratory and enteric infection. There are many serotypes for this virus, making it difficult to test for, and create a vaccine. Coronavirus can present as either diarrhea and/or respiratory illness; transmitted through nasal discharge and/or feces. Animal reservoirs continue to spread the disease, and make eradication almost impossible. Clinical disease will likely occur between days 10-14, and present for up to 4 days. Clinical Signs • Diarrhea - Watery • Nasal Discharge • Coughing Prevention/Treatment: Prevention is difficult due to wild animals transmitting the disease. Keeping wild animals out of animal enclosures is essential. Isolation of infected animals is critical to preventing the spread of Coronavirus. Adequate colostrum intake, along with a good vaccination program will help prevent clinical disease. Learn more about the positive effects of Farmtan's active ingredient on Coronavirus HERE. Cryptosporidium Cryptosporidium Parvum is a single-celled parasite responsible for causing infection in young calves. The infection takes place within the first four weeks of a calves' life, afterwards immunity has developed within the calf. The parasite is either passed from the cow or spread through infected water sources. Clinical Signs • Diarrhea - Watery, Bloody, Mucus present • Colic • Depression Prevention/Treatment: Good sanitary conditions, especially clean water is essential in preventing transmission of cryptosporidium. Isolation of sick calves will help reduce the effect on the overall herd. There is some good effect of calves given adequate colostrum, however this is likely helping by reducing other pathogenic loads rather than a direct effect on Cryptosporidium, itself. Farmatan fed prior to calving has been shown to disrupt the life-cycle and reduce transmission from the cow. The direct action of Farmatan on the parasite makes it an excellent choice for treating calves. Learn more about the positive effect of Farmatan's active ingredient HERE. E. Coli Escherichia Coli is a bacterial infection that affects calves within the first week of their life. The bacteria colonize in the lower intestine and produce a toxin. The toxin causes excessive secretion of fluids. The zoonotic disease has special importance in food safety and human health. Colostrum and natural immunity are often not sufficient in preventing infection in cases of high bacterial concentrations. Clinical Signs • Diarrhea - Creamy, Yellow • Abdominal Pains • Fever • Vomiting Prevention/Treatment: The best prevention methods for E. Coli include: clean water, dry bedding/environment, isolation of infected animals, and vaccination. Treatment with antibiotics and oral fluids have great benefits in reducing clinical symptoms of the disease. Farmatan has been shown to reduce bacterial load and help prevent infection. Learn more about the positive effects of Farmatan's active ingredient HERE. Rotavirus Rotavirus in calves is caused by a virus belonging to the Reoviridae family, as a non-enveloped RNA virus. Rotavirus is thought to be the most common cause of neonatal diarrhea in calves. The virus tends to affect calves between the age of 1-day-old up to a month, with most cases presenting within the first week of life. Shedding and reinfection can happen in older calves and cows. Clinical symptoms are rarely present after the first month of life; older animals tend to either be carriers or asymptomatic. The majority of herds have some level present, with transmission likely happening during or shortly after birth. Clinical Signs • Diarrhea - Pale Yellow, Bloody • Dehydrated • Dull calves • Reluctant to drink Prevention/Treatment: The ideal scenario is to prevent infection through, sanitary facilities (calving barn), outdoor calf housing, and a good vaccination program. Colostrum will provide much needed antibodies, protecting the calf before their immune system is fully developed to combat the disease. Farmatan fed prior to calving can help reduce the pathogen load of the cow, reducing the likelihood of transmission. Farmatan supplemented in the milk has been shown to decrease the virus' ability to cause infection and clinical disease. The best treatment for calves already presenting clinical disease is to administer oral fluids/electrolytes to rehydrate the calf. Learn more about the positive effect of Farmatan's active ingredient HERE. Salmonella Salmonella infection of cattle is caused by a variety of species within the family. While the disease is uncommon in cattle with little effect on calf health, it has massive implications for human health and food safety. The bacteria spreads through direct contact or contaminated feed & water. This disease is highly regulated by the USDA. The most severe cases of salmonella affect calves between the ages of 7-10 days old. Clinical Signs • Diarrhea - Bloody (flakes of slough tissue), Watery, Mucus present • Lethargic • Fever Prevention/Treatment: Prevention is always the best option: provide clean water, feed, and bedding. Isolate infected animals, ensure adequate colostrum intake, and develop a vaccination program with your veterinarian. Treatment with antibiotics and fluids (oral or intravenous) greatly increases the survival rate of calves infected with Salmonella. Farmatan has been shown to help reduce the likelihood of infection by protecting the gut, and reduce recovery time of infected animals. LEARN MORE ABOUT IMOGENE INGREDIENTS PRODUCTS Paul Mitchell & Paul Martin on RFD TV Rural American Live! FEATURING Chris Wasem, Wasem Red Angus https://www.wasemredangus.com/ @WasemReds Paul Mitchell Imogene Ingredients https://www.imogeneingredients.com/farmatanusa @farmatanusa Kirk Donsbach: Stone X Financial https://www.stonex.com/ @StoneXGroupInc Mark Van Zee Livestock Market, Equine Market, Auction Time https://www.auctiontime.com/ https://www.livestockmarket.com/ https://www.equinemarket.com/ @LivestockMkt @EquineMkt @AuctionTime Shaye Koester Casual Cattle Conversation https://www.casualcattleconversations.com/ @cattleconvos Questions & Concerns From The Field? Call or Text your questions, or comments to 707-RANCH20 or 707-726-2420 Or email RanchItUpShow@gmail.com FOLLOW Facebook/Instagram: @RanchItUpShow SUBSCRIBE to the Ranch It Up YouTube Channel: @ranchitup Website: RanchItUpShow.com https://ranchitupshow.com/ The Ranch It Up Podcast available on ALL podcasting apps. Rural America is center-stage on this outfit. AND how is that? Because of Tigger & BEC... Live This Western Lifestyle. Tigger & BEC represent the Working Ranch world by providing the cowboys, cowgirls, beef cattle producers & successful farmers the knowledge and education needed to bring high-quality beef & meat to your table for dinner. Learn more about Jeff 'Tigger' Erhardt & Rebecca Wanner aka BEC here: TiggerandBEC.com https://tiggerandbec.com/ #RanchItUp #StayRanchy #TiggerApproved #tiggerandbec #rodeo #ranching #farming References https://www.stonex.com/ https://www.livestockmarket.com/ https://www.equinemarket.com/ https://www.auctiontime.com/ https://gelbvieh.org/ https://www.imogeneingredients.com/ https://alliedgeneticresources.com/ https://westwayfeed.com/ https://medoraboot.com/ https://www.bek.news/dakotacowboy http://www.gostockmens.com/ https://www.lucky7angus.com/ https://www.bredforbalance.com/ https://www.wasemredangus.com/ https://ranchchannel.com/
Start the new season off with the most success you can by keeping scours away for good! Plus we pack this one with news updates from Capitol Hill, export updates and forecasts for 2024. Join Jeff 'Tigger' Erhardt, the Boss Lady Rebecca Wanner aka 'BEC', and our crew as we bring you the latest in markets, news, and Western entertainment on this all-new episode of the Ranch It Up Radio Show. Be sure to subscribe on your favorite podcasting app or on the Ranch It Up Radio Show YouTube Channel. EPISODE 162 DETAILS Scours attacks on day 1 of a calf's life. The best remedy is to be proactive versus reactive, and we have the solution for you. It is Farmatan from Imogene Ingredients! But here is the kicker. It is not an overnight magic cure all. We need to get this into the cows diet 60 to 90 days prior to calving to get maximum results. It is simple and easy. Just ask your feed supplier for Farmatan. You can feed in a lick tub form, as a liquid, in a TMR ration, and/or free choice. We go through the details and success stories with Paul Mitchell with Imogene Ingredients, who brings us Farmatan. Bec shares news from Capitol Hill, beef import information from Paraguay, and the WASDE Report for the 2024 forecast. But that's not all. We have market updates, sale barn reports and lots more, even some Christmas gift ideas from the crew from Medora Boot and Western Wear. And our Top Hand this week goes to Cracker Johnson. Hear his story! We have it all for you in this jam-packed episode of The Ranch It Up Radio Show! As always Tigger & BEC and the Ranch It Up crew dive into the latest agriculture news, rodeo action not to miss, and cover the cattle markets. WHAT CAUSES SCOURS IN BEEF CATTLE/CALVES Clostridia-Enterotoxemia The most common form of Clostridium in cattle is caused by Clostridium perfringens. The gram-positive bacteria are a challenge due to its ability to form spores and lay dormant for long-periods of time. The bacteria reproduce by releasing spores into its environment (soil, feed, manure). The spores can even lay dormant in the animal's intestine until opportunity presents itself. Infection takes place either through ingestion of spores or through an open wound. The most severe cases happen within the first month of a calf's life, and can result in sudden death. Clinical Signs • Diarrhea - Bloody, Mucus Present, Bubbly • Dehydrated • Bloat • Blindness Prevention/Treatment: Prevention can be difficult due to the Clostridia spores being extremely durable and present almost everywhere. Complete cleanout and disinfection between calves is helpful, but not always effective. A good vaccination program will reduce clinical disease. The best method is to develop good gut health and the immune system of the calf. Farmatan has been shown to strengthen the intestinal wall, helping to prevent infection from taking hold. Coccidiosis Cattle are host to numerous species of Coccidia, a single-celled protozoal parasite. Infection and clinical symptoms can happen any time during a calf's life, with the most severe reaction usually occurring between 3-6 weeks of age. The life-cycle of coccidia requires time to infect the intestine causing destruction of the mucosal and epithelial lining. The oocytes mature outside the host in warm, moist environments before being consumed, causing infection of a new host. Clinical Signs • Diarrhea - Watery, Bloody • Depression • Weight Loss Prevention/Treatment: Prevention of Coccidiosis is possible by keeping young calves separate from older animals, providing clean water and feed, and dry conditions. Isolation of infected animals is key to preventing transmission. Keeping the pen dry is the most important step a farmer/rancher can take in preventing Coccidiosis. Treatment can have a good impact on reducing secondary disease, and speeding up recovery time. Farmatan has been shown to disrupt the reproductive cycle of Coccidia; and may help strengthen the intestinal wall to prevent infection, in both the cow and calf. Coronavirus Bovine Coronavirus is a ubiquitous, envelope-viral disease, causing respiratory and enteric infection. There are many serotypes for this virus, making it difficult to test for, and create a vaccine. Coronavirus can present as either diarrhea and/or respiratory illness; transmitted through nasal discharge and/or feces. Animal reservoirs continue to spread the disease, and make eradication almost impossible. Clinical disease will likely occur between days 10-14, and present for up to 4 days. Clinical Signs • Diarrhea - Watery • Nasal Discharge • Coughing Prevention/Treatment: Prevention is difficult due to wild animals transmitting the disease. Keeping wild animals out of animal enclosures is essential. Isolation of infected animals is critical to preventing the spread of Coronavirus. Adequate colostrum intake, along with a good vaccination program will help prevent clinical disease. Learn more about the positive effects of Farmtan's active ingredient on Coronavirus HERE. Cryptosporidium Cryptosporidium Parvum is a single-celled parasite responsible for causing infection in young calves. The infection takes place within the first four weeks of a calves' life, afterwards immunity has developed within the calf. The parasite is either passed from the cow or spread through infected water sources. Clinical Signs • Diarrhea - Watery, Bloody, Mucus present • Colic • Depression Prevention/Treatment: Good sanitary conditions, especially clean water is essential in preventing transmission of cryptosporidium. Isolation of sick calves will help reduce the effect on the overall herd. There is some good effect of calves given adequate colostrum, however this is likely helping by reducing other pathogenic loads rather than a direct effect on Cryptosporidium, itself. Farmatan fed prior to calving has been shown to disrupt the life-cycle and reduce transmission from the cow. The direct action of Farmatan on the parasite makes it an excellent choice for treating calves. Learn more about the positive effect of Farmatan's active ingredient HERE. E. Coli Escherichia Coli is a bacterial infection that affects calves within the first week of their life. The bacteria colonize in the lower intestine and produce a toxin. The toxin causes excessive secretion of fluids. The zoonotic disease has special importance in food safety and human health. Colostrum and natural immunity are often not sufficient in preventing infection in cases of high bacterial concentrations. Clinical Signs • Diarrhea - Creamy, Yellow • Abdominal Pains • Fever • Vomiting Prevention/Treatment: The best prevention methods for E. Coli include: clean water, dry bedding/environment, isolation of infected animals, and vaccination. Treatment with antibiotics and oral fluids have great benefits in reducing clinical symptoms of the disease. Farmatan has been shown to reduce bacterial load and help prevent infection. Learn more about the positive effects of Farmatan's active ingredient HERE. Rotavirus Rotavirus in calves is caused by a virus belonging to the Reoviridae family, as a non-enveloped RNA virus. Rotavirus is thought to be the most common cause of neonatal diarrhea in calves. The virus tends to affect calves between the age of 1-day-old up to a month, with most cases presenting within the first week of life. Shedding and reinfection can happen in older calves and cows. Clinical symptoms are rarely present after the first month of life; older animals tend to either be carriers or asymptomatic. The majority of herds have some level present, with transmission likely happening during or shortly after birth. Clinical Signs • Diarrhea - Pale Yellow, Bloody • Dehydrated • Dull calves • Reluctant to drink Prevention/Treatment: The ideal scenario is to prevent infection through, sanitary facilities (calving barn), outdoor calf housing, and a good vaccination program. Colostrum will provide much needed antibodies, protecting the calf before their immune system is fully developed to combat the disease. Farmatan fed prior to calving can help reduce the pathogen load of the cow, reducing the likelihood of transmission. Farmatan supplemented in the milk has been shown to decrease the virus' ability to cause infection and clinical disease. The best treatment for calves already presenting clinical disease is to administer oral fluids/electrolytes to rehydrate the calf. Learn more about the positive effect of Farmatan's active ingredient HERE. Salmonella Salmonella infection of cattle is caused by a variety of species within the family. While the disease is uncommon in cattle with little effect on calf health, it has massive implications for human health and food safety. The bacteria spreads through direct contact or contaminated feed & water. This disease is highly regulated by the USDA. The most severe cases of salmonella affect calves between the ages of 7-10 days old. Clinical Signs • Diarrhea - Bloody (flakes of slough tissue), Watery, Mucus present • Lethargic • Fever Prevention/Treatment: Prevention is always the best option: provide clean water, feed, and bedding. Isolate infected animals, ensure adequate colostrum intake, and develop a vaccination program with your veterinarian. Treatment with antibiotics and fluids (oral or intravenous) greatly increases the survival rate of calves infected with Salmonella. Farmatan has been shown to help reduce the likelihood of infection by protecting the gut, and reduce recovery time of infected animals. COW COUNTRY NEWS Meat industry takes aim at UN's anti-meat claims at COP28 House Coalition Opposes Plan To Accept Importation Of Paraguay Beef WASDE Livestock Report For 2023 SALE BARN REPORTS Stockmens Livestock Exchange, Dickinson, ND TOP HAND Chad “Cracker” Johnson FEATURING Paul Mitchell Imogene Ingredients https://www.imogeneingredients.com/farmatanusa @farmatanusa Austin Henderson Stockmen's Livestock Exchange Dickinson, ND http://www.gostockmens.com/ https://www.cattleusa.com @gostockmens Shaye Koester Casual Cattle Conversation https://www.casualcattleconversations.com/ @cattleconvos Chad “Cracker” Johnson https://crackerauctionservice.com/ Kirk Donsbach: Stone X Financial https://www.stonex.com/ @StoneXGroupInc Mark Van Zee Livestock Market, Equine Market, Auction Time https://www.auctiontime.com/ https://www.livestockmarket.com/ https://www.equinemarket.com/ @LivestockMkt @EquineMkt @AuctionTime Questions & Concerns From The Field? Call or Text your questions, or comments to 707-RANCH20 or 707-726-2420 Or email RanchItUpShow@gmail.com FOLLOW Facebook/Instagram: @RanchItUpShow SUBSCRIBE to the Ranch It Up YouTube Channel: @ranchitup Website: RanchItUpShow.com https://ranchitupshow.com/ The Ranch It Up Podcast available on ALL podcasting apps. Rural America is center-stage on this outfit. AND how is that? Because of Tigger & BEC... Live This Western Lifestyle. Tigger & BEC represent the Working Ranch world by providing the cowboys, cowgirls, beef cattle producers & successful farmers the knowledge and education needed to bring high-quality beef & meat to your table for dinner. Learn more about Jeff 'Tigger' Erhardt & Rebecca Wanner aka BEC here: TiggerandBEC.com https://tiggerandbec.com/ #RanchItUp #StayRanchy #TiggerApproved #tiggerandbec #rodeo #ranching #farming References https://www.stonex.com/ https://www.livestockmarket.com/ https://www.equinemarket.com/ https://www.auctiontime.com/ https://gelbvieh.org/ https://www.imogeneingredients.com/ https://alliedgeneticresources.com/ https://westwayfeed.com/ https://medoraboot.com/ https://www.bek.news/dakotacowboy http://www.gostockmens.com/ https://www.usda.gov/oce/commodity/wasde https://www.meatingplace.com/Industry/News/Details/112513 https://hpj.com/2023/12/05/house-coalition-opposes-plans-to-accept-importation-of-paraguay-beef/ https://hpj.com/2023/12/01/wasde-livestock-report-showed-lower-production-in-2023/ https://crackerauctionservice.com/
Dr. Nirala Jacobi interviews Dr. Mark Davis about helminth therapy and fecal microbiota transplantation (FMT) in the treatment of various conditions. Helminth therapy involves using tiny worm-like organisms called helminths as medicine for humans. Dr. Davis explains that there are four helminths that have been found to be safe and beneficial for humans. These helminths can be used to treat conditions such as multiple sclerosis, ulcerative colitis, Crohn's disease, and autism spectrum disorder. FMT, on the other hand, involves transplanting fecal microbiota from a healthy donor into the gut of a patient. FMT has been found to be effective in treating conditions such as Clostridium difficile (C. diff) colitis and hepatic encephalopathy. Dr. Davis also discusses his new ventures in Panama, where he plans to offer helminth therapy and FMT in a hospital setting. He also mentions his work on vaginal microbiota transplantation for women's health conditions. Dr Mark Davis, ND is a 2011 graduate of NUNM, and a fellow of the American College of Naturopathic Gastroenterology. He's on the board of directors of the Gastroenterology Association of Naturopathic Physicians, and the editorial board of the Natural Medicine Journal. Dr. Davis teaches the naturopathic gastroenterology course at Southwest College of Naturopathic Medicine, and he has focused on patients with IBD since 2016.
I am a sucker for supplements with extensive and impressive research to prove their biohacking benefits, and OMNi-BiOTiC is one of them. Research studies by OMNi-BiOTiC show a 50% or 70% improvement in things like brain function, insulin sensitivity, and detoxification which is really compelling—and exactly why we have Hannah Kleinfield on the show today.Hannah Kleinfeld is the Chief Operating Officer of Allergosan USA, the U.S. joint-venture partner of Institut Allergosan, a global leader in microbiome science and gut health products. She is dedicated to educating about the importance of gut health as a foundation for wellbeing and passionate about helping others experience healthy and vibrant lives. That passion is clear in today's episode where she shares the research and broad-ranging benefits of the OMNi-BiOTiC line of probiotic supplements. We talk about why it's so important to have a thriving gut, the important link between gut health and brain function, what is most likely to harm our guts, especially in the US, and how to find which probiotic is right for you. If you're into biohacking, whether you're already doing really well and you're looking for what's next, or you've still got that extra 20 pounds that won't budge but you can see you're moving in the right direction, this might be a really big step to help move you toward your goals. If you'd like to try these products for yourself, go to omnibioticlife.com and use code DAVE20 to get 20% off.(02:24) Revitalizing Gut Health with New Technology• Repairing her gut after Lyme disease• The difference between European and US-based supplement brands• Shop OMNi-BiOTiC (use code DAVE20 to get 20% off)• Where to start with probiotics• What is most harmful to the gut(19:25) Probiotic Power: Detoxing, Brain Boosting & Insulin Resistance• How to address a bad bacteria—Clostridium difficile• How a probiotic can change your brain activity• Delivery method of OMNi-BiOTiC• Exploring the benefits of OMNi-BiOTiC Hetox for liver support and insulin resistance• Recommended tests for monitoring what's going on in your body(34:41) All You Need to Know About Probiotics • Why OMNi-BiOTiC doesn't use spores• Pairing OMNi-BiOTiC with other probiotics• What people should know about probiotics• Tips for clearing SIBO• When to take probiotics after being on antibiotics ResourcesDave Asprey's NEW Book ‘Smarter Not Harder' is out now: https://daveasprey.com/books Website: omnibioticlife.com (use code DAVE20 to get 20% off)Instagram: @omnibioticlifeThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
HelixTalk - Rosalind Franklin University's College of Pharmacy Podcast
In this episode, we announce the second iteration of the HelixTalk Drug Superlative Awards -- awards given to medications on the market that are outstanding or notorious. In announcing these completely fictitious awards, we review key clinical pearls and pitfalls that every clinician should be aware of with these notable medications. Key Concepts The award for the most unique phase III patient population for a widely used medication goes to … Pneumovax-23 (PPSV-23) for its predecessor versions that were studied in South African novice gold miners. The award for the most misunderstood boxed warning goes to … all of the DOACs (but specifically apixaban and rivaroxaban). In particular, due to BOTH an increased risk of thrombosis and bleeding when switching from a DOAC to warfarin therapy in patients with atrial fibrillation. The award for the biggest difference between pharmacokinetic properties and pharmacodynamic effects goes to … aspirin due to its short-half life and short duration of analgesic effect and yet very prolonged antiplatelet effect. The award for the drug that should be dispensed with extra toilet paper … TIE between irinotecan and clindamycin. The most common dose-limiting adverse effect of irinotecan is diarrhea – loperamide is extensively used in these patients. Clindamycin earns the award because it is the antibiotic most associated with Clostridium difficile-associated diarrhea (CDAD). References Smit P, Oberholzer D, Hayden-Smith S, Koornhof HJ, Hilleman MR. Protective efficacy of pneumococcal polysaccharide vaccines. JAMA. 1977;238(24):2613-2616. Farrar JL, Childs L, Ouattara M, et al. Systematic Review and Meta-Analysis of the Efficacy and Effectiveness of Pneumococcal Vaccines in Adults. Pathogens. 2023;12(5):732. Published 2023 May 19. doi:10.3390/pathogens12050732 Pavia M, Bianco A, Nobile CG, Marinelli P, Angelillo IF. Efficacy of pneumococcal vaccination in children younger than 24 months: a meta-analysis. Pediatrics. 2009;123(6):e1103-e1110. doi:10.1542/peds.2008-3422 Deshpande A, Pasupuleti V, Thota P, Pant C, Rolston DD, Sferra TJ, Hernandez AV, Donskey CJ. Community-associated Clostridium difficile infection and antibiotics: a meta-analysis. J Antimicrob Chemother. 2013 Sep;68(9):1951-61. doi: 10.1093/jac/dkt129.
An ever-present spectre looming over the hearts of general surgeons everywhere! Please join our Emergency General Surgery team for a journal review about Clostridium difficile (C. diff) infection. Dr. Ashlie Nadler and Dr. Jordan Nantais are joined by guest Dr. Marika Sevigny, recent graduate of trauma and acute care surgery at the University of Toronto, as Dr. Graham Skelhorne-Gross prepares for his upcoming fellowship at Harborview. Paper 1: Ahmed et al. Risk factors of surgical mortality in patients with Clostridium difficile colitis. A novel scoring system. Eur J Trauma Emerg Surg. 2022 Jun. - Risk score development study using data from the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) - 525 adult (18-89) patients undergoing colectomy between 2012 and 2016 - Split data into training (80%) and testing (20%) datasets - Identified mortality risk factors to create and validate a scoring system - Scores ranged from 0 to 37 with the highest score predicting an 83.9% risk of mortality - This scoring system appears relatively straight-forward and methodically sound but the lack of a currently available calculator limits use to some degree Paper 2: McKechnie et al. Total Abdominal Colectomy Versus Diverting Loop Ileostomy and Antegrade Colonic Lavage for Fulminant Clostridioides Colitis: Analysis of the National Inpatient Sample 2016-2019. J Gastrointest Surg. 2023 Apr 20. - Retrospective cohort study of adults (18+) in the National Inpatient Sample (NIS) admitted between Jan 2016 and Dec 2019 for C. difficile colitis, undergoing either a total abdominal colectomy (TAC) or diverting loop ileostomy (DLI) with antegrade vancomycin enemas - Focus on not only mortality and complications but also admission cost and length of stay - 886 TAC and 409 DLI patients were identified - Multivariable logistic regression analysis showed no difference in mortality or overall complications - TAC patients had shorter admissions (mean difference 4.06 days) and lower cost (mean difference $79,715.34) - Study was limited as it considered only the initial admission and is unable to provide data on outcomes and costs beyond this time - Furthermore, there is consideration for disease severity in the analysis, which may impede the ability to compare the two operative approaches Please visit https://behindtheknife.org to access other high-yield surgical education podcasts, videos and more. If you liked this episode, check out our other Emergency General Surgery episodes here: https://behindtheknife.org/podcast-category/emergency-general-surgery/
Les vamos a explicar qué onda con la gastroenteritis bacteriana y cómo es que afecta nuestra salud y a dónde ir para mejorar. No saben, cuentahabientes, he pasado unos días infernales y todo porque he traído unas bacterias que andan cañonas en esta temporada: E.Coli, Shighela, Clostridium difficile… y para aquellos que andan con el estómago hecho pedazos, les traigo a nuestro infectólogo de cabecera para que nos explique qué onda con la gastroenteritis bacteriana que está en los alimentos, el agua, las superficies, nuestras manos en todos lados!.
This is Garrison Hardie with your CrossPolitic Daily News Brief for Tuesday, May 9th, 2023. Samaritan Ministries: Don’t be limited by restrictive networks. There’s another way. A Biblical way. Samaritan Ministries. Say you have a medical need. You don’t have to check and see what hospital is in your network, or be concerned about the doctor being in-network, too. No. You go to the hospital you choose, and don’t give a second thought as to what’s in-network and what’s not, because with Samaritan Ministries, you’re in control of your health care. Afterwards, fellow members pray for you, and send money directly to you to help you pay your medical bills. And when they have a medical need, you’ll do the same for them. That’s what Biblical health care sharing looks like. Check it out today at samaritan ministries dot org slash cross politic First, we start with the news of a coronation for our friends across the pond. https://www.cnn.com/2023/05/06/europe/coronation-king-charles-ckc-gbr-intl/index.html King Charles III is crowned in once-in-a-generation ceremony Britain’s King Charles III has been crowned in a once-in-a-generation royal event witnessed by hundreds of high-profile guests inside Westminster Abbey, as well as tens of thousands of well-wishers who gathered in central London despite the rain. While Charles became King on the death of his mother, Queen Elizabeth II last September, the coronation on Saturday was the formal crowning of the monarch. The service was a profoundly religious affair, reflecting the fact that aside from being head of state of the United Kingdom and 14 other countries, Charles is also the Supreme Governor of the Church of England. In the most significant moment of the day, Archbishop of Canterbury Justin Welby placed the 360-year-old St. Edward’s Crown on Charles’ head. The spiritual leader of the Anglican Church then declared: “God Save the King.” The intricate service lasted just over two hours – about an hour shorter than Elizabeth II’s coronation in 1953 – and followed a traditional template that has stayed much the same for more than 1,000 years. However, it has been modernized in certain key ways. The archbishop acknowledged the multiple faiths observed in the UK during the ceremony, saying the Church of England “will seek to foster an environment in which people of all faiths may live freely.” The King took the Coronation Oath and became the first monarch to pray aloud at his coronation. In his prayer he asked to “be a blessing” to people “of every faith and conviction.” In what is considered the most sacred part of the ceremony, the King was anointed with holy oil by the Archbishop of Canterbury. He was also presented with the coronation regalia, including the royal Robe and Stole, in what is known as the investiture part of the service. Then, for the first time in coronation history, the archbishop invited the British public, as well as those from “other Realms,” to recite a pledge of allegiance to the newly crowned monarch and his “heirs and successors.” Ahead of the event, some parts of the British media and public interpreted the invitation as a command, reporting that people had been “asked” and “called” to swear allegiance to the King. In the face of such criticism, the Church of England revised the text of the liturgy so that members of the public would be given a choice between saying simply “God save King Charles” or reciting the full pledge of allegiance. The ceremony also included a reading from the Bible by UK Prime Minister Rishi Sunak and, in another coronation first, gospel music. Once the King was crowned, his wife, Queen Camilla, was crowned in her own, shorter ceremony with Queen Mary’s Crown – marking the first time in recent history that a new crown wasn’t made specifically for this occasion. After the ceremony, the newly crowned King and Queen rode back to Buckingham Palace in a much larger parade, featuring 4,000 members of the armed forces, 250 horses and 19 military bands. The pomp and pageantry concluded with a royal salute and the customary balcony appearance by the King and family members. They and the crowds below watched a flypast of military aircraft, slimmed down because of the poor weather. Despite the splendor of the occasion, it has not been without controversy. Some have objected to millions of pounds of taxpayers’ money being spent on a lavish ceremony at a time when millions of Britons are suffering a severe cost-of-living crisis. Security is by far the most costly element of large events and the Met said ahead of time that Saturday would be the largest one-day policing operation in decades, with more than 11,500 officers on duty in London. The coronation has also attracted anti-monarchy demonstrations, with a small number of protesters arrested in central London on Saturday morning before the event began. Republic, a campaign group that calls for the abolition of the monarchy, said the idea of the “homage of the people” was “offensive, tone deaf and a gesture that holds the people in contempt.” Some eyebrows were also raised earlier this week when a controversial and widely criticized UK public order bill came into force. Since the death of Queen Elizabeth II last year, there have been a number of instances of anti-monarchists turning up at royal engagements to voice their grievances against the institution. The new rules, signed into law by the King on Tuesday, just days before the coronation, empower the police to take stronger action against peaceful protesters. https://thepostmillennial.com/biden-to-veto-house-remain-in-mexico-bill?utm_campaign=64487 Biden to veto House 'remain in Mexico' bill On Monday, the White House announced that Joe Biden would veto an immigration bill coming out of the House of Representatives that would reinstitute several Trump-era policies including construction of the border wall and the remain in Mexico policy, which stated that anyone seeking asylum had to wait in Mexico as their claim was processed. According to the Associated Press, the White House Office of Management and Budget said in a statement, "While we welcome Congress' engagement on meaningful steps to address immigration and the challenges at the border, this bill would make things worse, not better. Because this bill does very little to actually increase border security while doing a great deal to trample on the nation’s core values and international obligations, it should be rejected." On Thursday, the House is set to vote on the 213-page Secure the Border Act. Thursday also marks the expiration of Title 42, the Trump-era policy instituted under Covid that granted Border Patrol and Department of Homeland Security officials the ability to expel illegal immigrants over health concerns. The Secure the Border Act would also require employers to verify a worker's immigration status for employment and institute the E-Verify system House Majority Leader Steve Scalise said, "Joe Biden sent a message that America’s border is open, and millions of people answered that call and started coming across our border illegally. We’re going to show the president how to solve the problem." The Daily Mail reports, the Secure the Border Act would limit federal funds for NGOs (non-governmental organizations) that aid illegal immigrants crossing the border, would end Biden's expedited entry policy for Nicaraguans, Venezuelans, Haitians, and Cubans, and grant more money for hiring additional border agents. Joe Biden loosened restrictions along the southern border after he took office and HHS Secretary Alejandro Mayorkas made the announcement that migrants seeking asylum would be permitted entry into the US as would unaccompanied minors. US Border Patrol Chief Raul Ortiz said that over the weekend 26,382 apprehensions were made by border patrol and that 11 pounds of fentanyl and 83 pounds of meth were seized. Mexican cartels have exploited Biden's border crisis, with 2,378,944 illegal immigrant encounters reported in the 2022 fiscal year and 1,659,206 reported in FY 2021, by trafficking humans and drugs, especially fentanyl across the border in record numbers. https://www.dailywire.com/news/airlines-may-soon-be-on-the-hook-for-delayed-and-canceled-flights-transportation-dept-says Airlines May Soon Be On The Hook For Delayed And Canceled Flights, Transportation Dept Says Transportation Secretary Pete Boo-tuh-jeg announced on Monday that the agency introduced rules requiring airlines to reimburse customers who incur expenses due to certain delayed and canceled flights, a move which comes as the industry faces elevated demand and a constrained labor force. The proposed rules, which would apply when an airline delays a flight for more than three hours or cancels a flight for a “controllable” reason, would mandate that the firms offer compensation for stranded passengers, as well as a meal or meal voucher, overnight accommodations, and ground transportation between the airport and hotel. “When an airline causes a flight cancellation or delay, passengers should not foot the bill,” Buttigieg said in a statement, noting that the proposed reimbursement rules would be the first in American history. The move comes after Southwest Airlines experienced holiday travel disruptions last year due to extreme winter weather conditions, staff shortages, and an outdated computer system. The carrier canceled thousands of flights days after other carriers had resumed normal operations. Buttigieg told the company, which has since promised to compensate passengers for all expenses incurred during that time, that the disruptions were “unacceptable” and promised that his agency would exercise “the fullest extent of its investigative and enforcement powers” to ensure customers are reimbursed. The new proposals also occur as the sector faces a severely limited pool of available pilots and frontline staff. Carriers previously encouraged commercial pilots to retire as worldwide lockdowns caused demand for air travel to plummet in the spring of 2020, worsening a previous trend toward a lack of available pilots. Elevated prices for airline tickets and a rapid return in travel demand, however, are now prompting lawmakers to consider the problem. Regional Airline Association CEO Faye Malarkey Black told members of the House Transportation and Infrastructure Committee last month that more than 50% of current pilots would be forced to retire within the next 15 years because of federal rules mandating that pilots exit their positions once they reach 65 years of age, even as only 8% of pilots are below 30 years of age due to the high cost of flight education. Buttigieg has opposed legislation that would increase the retirement threshold to 67 years of age, contending that “the answer is to make sure we have as many and as good pilots ready to take their place, to have a stronger pipeline.” https://www.nbcnews.com/health/health-news/fecal-transplant-pill-fda-approval-rcna81779 FDA approves first pill for fecal transplants, made from healthy bacteria in human waste U.S. health officials on Wednesday approved the first pill made from healthy bacteria found in human waste to fight dangerous gut infections — an easier way of performing so-called fecal transplants. The new treatment from Seres Therapeutics provides a simpler, rigorously tested version of stool-based procedures that some medical specialists have used for more than a decade to help patients. The Food and Drug Administration cleared the capsules for adults 18 and older who face risks from repeat infections with Clostridium difficile, a bacteria that can cause severe nausea, cramping and diarrhea. diff is particularly dangerous when it reoccurs, leading to between 15,000 and 30,000 deaths per year. It can be killed with antibiotics but they also destroy good bacteria that live in the gut, leaving it more susceptible to future infections. The new capsules are approved for patients who have already received antibiotic treatment. More than 10 years ago, some doctors began reporting success with fecal transplants — using stool from a healthy donor — to restore the gut’s healthy balance and prevent reinfections. The FDA approved the first pharmaceutical-grade version of the treatment last year from a rival drugmaker, Ferring Pharmaceuticals. But that company’s product — like most of the original procedures — must be delivered via the rectum. Cambridge, Mass.-based Seres will market its drug as a less invasive option. The treatment will be sold under the brand name Vowst and comes as a regimen of four daily capsules taken for three consecutive days. Both of the recent FDA approvals are the product of years of pharmaceutical industry research into the microbiome, the community of bacteria, viruses and fungi that live in the gut. Currently most fecal transplants are provided by a network of stool banks that have popped up at medical institutions and hospitals across the country. While the availability of new FDA-approved options is expected to decrease demand for donations from stool banks, some plan to stay open. The FDA warned in its approval announcement that the drug “may carry a risk of transmitting infectious agents. It is also possible for Vowst to contain food allergens,” the agency noted. The FDA approved the treatment based on a 180-patient study in which nearly 88% of patients taking the capsules did not experience reinfection after 8 weeks, compared with 60% of those who received dummy pills.
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