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Contributor: Taylor Lynch MD Educational Pearls: Melatonin is an endogenous hormone released primarily by the pineal gland Also released by extrapineal regions in the retina, the GI tract, and some immune cells Peak secretion occurs at night and is suppressed during the day Secretion and production decrease with age Older patients experience the greatest improvement in sleep latency and sleep quality Mechanism of action in the suprachiasmatic nucleus of the hypothalamus MT1 receptor Reduces normal firing MT2 receptor Shifts the circadian rhythm FDA approved for insomnia Decreases sleep latency by 7 minutes Increases total sleep time by 8 minutes FDA approved for circadian sleep-wake disorders Jet lag Most effective in west-to-east travel Best if crossing at least 5 time zones Shift work A study examined ED physicians and nurses with rotating shifts Modest increase in deep sleep percentage No difference in cognition or reaction time the day after taking melatonin Nurses on rotating night shifts experienced increased total sleep time by 20 minutes Dosing 0.5 - 3 mg is the most evidence-based dosing Higher doses increase the risk of rebound grogginess but do not improve outcomes References Ahmad SB, Ali A, Bilal M, et al. Melatonin and Health: Insights of Melatonin Action, Biological Functions, and Associated Disorders. Cell Mol Neurobiol. 2023;43(6):2437-2458. doi:10.1007/s10571-023-01324-w Herxheimer A, Petrie KJ. Melatonin for the prevention and treatment of jet lag. Cochrane Database Syst Rev. 2002;(2):CD001520. doi:10.1002/14651858.CD001520 Morgenthaler TI, Lee-Chiong T, Alessi C, Friedman L, Aurora RN, Boehlecke B, Brown T, Chesson AL Jr, Kapur V, Maganti R, Owens J, Pancer J, Swick TJ, Zak R; Standards of Practice Committee of the American Academy of Sleep Medicine. Practice parameters for the clinical evaluation and treatment of circadian rhythm sleep disorders. An American Academy of Sleep Medicine report. Sleep. 2007 Nov;30(11):1445-59. doi: 10.1093/sleep/30.11.1445. Erratum in: Sleep. 2008 Jul 1;31(7):table of contents. PMID: 18041479; PMCID: PMC2082098. Thottakam BMVJ, Webster NR, Allen L, Columb MO, Galley HF. Melatonin Is a Feasible, Safe, and Acceptable Intervention in Doctors and Nurses Working Nightshifts: The MIDNIGHT Trial. Front Psychiatry. 2020;11:872. Published 2020 Aug 27. doi:10.3389/fpsyt.2020.00872 Summarized and edited by Jorge Chalit, OMS4 Donate: https://emergencymedicalminute.org/donate/ Join our mailing list: http://eepurl.com/c9ouHf
The Intro to AOX Course is coming to Tempe, AZ! Join us for a hands-on deep dive into the clinical and business systems behind predictable full-arch success. Seats are limited - register now to secure your spot. https://products.sharedpractices.com/tfap-intro-to-aox-2026 In this episode of The Full Arch Podcast, Dr. Steven Vorholt shares exciting news about being selected for a main podium presentation at the American Academy of Implant Dentistry and reflects on the long path that led there. He discusses how teaching, mentorship, and strategic visibility have shaped his career trajectory. The conversation explores why reputation compounds over time, how hosting local study clubs can build referral networks, and why saying no to smaller opportunities creates space for higher-impact growth. This episode highlights how intentional positioning, not luck, drives long-term professional authority. Key Highlights: Teaching Builds Mastery - Verbalizing and mentoring sharpen clinical skill and credibility Reputation Compounds - Authority is built through consistent presence in the right rooms Intentional Calendar Design - Strategic opportunity selection creates higher-impact growth
This member-driven podcast is a benefit of membership of the Arizona Chapter of the American Academy of Pediatrics (AzAAP) and is intended for AzAAP pediatric healthcare members. No information or content in this podcast is intended to substitute or replace a consultation with a healthcare provider or specialist. All non-healthcare providers should reach out to their child's pediatrician for guidance. Music: Wallpaper by Kevin MacLeodLink: https://incompetech.filmmusic.io/song/4604-wallpaperLicense: http://creativecommons.org/licenses/by/4.0/
These days I sometimes have to remind myself to keep breathing. I think this is true of human beings across all of our differences and divides. But in a room in New York City just before the turn of this year, I was regrounded by this fierce and joyous conversation with Joy Harjo and Tracy K. Smith. I invite you to settle into your soft breathing body with these two wise women as companions and with a sense of poetry as a technology, as Tracy describes in her new book: a technology for rising to our truest, highest selves, even amidst grief and mystery and danger, and bearing witness to each other as we do so. I think all of us in the room left a little more lighthearted and alive as this conversation unfolded. I hope that will be your experience too. Tracy K. Smith and Joy Harjo are former U.S. poet laureates, beloved On Being guests, and friends. They are each wildly and deservedly awarded and not just as poets — Tracy also as a teacher and professor at Harvard, Joy as a saxophonist and painter. We were brought together at Symphony Space in Manhattan to celebrate their newest books: Fear Less by Tracy and Girl Warrior by Joy. Find an excellent transcript of this show, edited by humans, on our show page. Sign yourself and others up for The Pause to be on our mailing list for all things On Being and to receive Krista's monthly Saturday newsletter, including a heads up on new episodes, special offerings, recommendations, and event invitations. Joy Harjo was the 23rd Poet Laureate of the United States. Among many honors, she has received the Poetry Society of America's Frost Medal and a National Humanities Medal. She is the inaugural Artist-in-Residence for the Bob Dylan Center in Tulsa, Oklahoma. She lives on the Muscogee Nation Reservation in Oklahoma. Her new book of essays is Girl Warrior. Forthcoming in 2026 is her 12th book of poetry and a new album co-produced with esperanza spalding. Tracy K. Smith was the 22nd Poet Laureate of the United States. She teaches at Harvard University, where she is Boylston Professor of Rhetoric and Oratory, Professor of African and African American Studies, and Susan S. and Kenneth L. Wallach Professor at the Harvard Radcliffe Institute. Among her many honors, she has been awarded the Pulitzer Prize for Poetry and is a Chancellor of the American Academy of Arts and Sciences. Her new memoir is Fear Less. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this episode of The Behavioral View, Nissa Van Etten, Olivia Teal, Elizabeth Barajas, and Yagnesh Vadgama discuss the evolution of outcomes-based care within applied behavior analysis (ABA). Drawing from extensive experience in both clinical practice and payer systems, Vadgama outlines the differences between traditional fee-for-service models and outcomes-based care frameworks. The panel explores how standardized assessments, aggregate data analysis, and empirically supported dosing recommendations can create greater alignment between providers and payers while maintaining individualized clinical decision-making. The discussion addresses administrative burden, prior authorization processes, value-based payment arrangements, caregiver involvement, social determinants of health, and interdisciplinary collaboration. Emphasis is placed on transparency, data-driven decision making, and protecting the integrity of behavior analytic practice while demonstrating measurable outcomes at both the individual and population levels. This course provides practical insight into how outcomes-based care models may shape the future of ABA service delivery. To earn CEUs for listening, click here, log in or sign up, pay the CEU fee, + take the attendance verification quiz to generate your certificate! Don't forget to subscribe and follow and leave us a rating and review. Show Notes: References Frazier, T. W., Youngstrom, E. A., Speer, L., Embacher, R., Law, P., Constantino, J., Findling, R. L., Hardan, A. Y., & Eng, C. (2014). Validation of proposed DSM-5 criteria for autism spectrum disorder. Journal of the American Academy of Child & Adolescent Psychiatry, 53(1), 28–40. https://doi.org/10.1016/j.jaac.2013.10.012 Frazier, T. W., Klingemier, E. W., Beukemann, M., Speer, L., Markowitz, L., Parikh, S., & Strauss, M. S. (2021). Development and validation of the Autism Impact Measure (AIM). Journal of Autism and Developmental Disorders, 51, 3407–3421. https://doi.org/10.1007/s10803-020-04795-1 Smith, P. C., Sagan, A., Siciliani, L., & Figueras, J. (2023). Building on value-based health care: Towards a health system perspective. Health Policy, 138, 104918. https://doi.org/10.1016/j.healthpol.2023.104918 AI.Measures Scientific Support Ferguson, E. F., Frazier, T. W., Hardan, A. Y., & Uljarević, M. (2025). Challenging behavior domains in individuals with neurodevelopmental genetic syndromes: The role of psychological features. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 0(1), 1-12 Frazier, T. W., Huba, K., Frazier, A. R., Womack, R. A., Youngstrom, E. A., Chetcuti, L., Hardan, A. Y., & Uljarevic, M. (2025). Maximizing accurate detection of divergence from normative expectation in behavioral intervention outcome assessment. Research in Autism, 126, 202646. Frazier, T. W., Youngstrom, E. A., Frazier, A. R., & Uljarevic, M. (2025). A critical appraisal of the measurement of adaptive social communication behaviors in the behavioral intervention context. Behavioral Sciences, 15(6), 722 Frazier, T.W., Helton, M., Akouri, C., Chetcuti, L., Uljarevic, M. (2025) Identifying Reliable Change In Outcome Assessments for Behavioral Intervention. Behavioral Interventions. Frazier, T. W., Dimitropoulos, A., Abbeduto, L., Armstrong-Brine, M., Kralovic, S., Shih, A., Hardan, A. Y., Youngstrom, E. A., Uljarevic, M., Verbal Beginnings, T. (2024). Psychometric evaluation of the Autism Symptom Dimensions Questionnaire. Developmental Medicine and Child Neurology. Frazier, T. W., Busch, R. M., Klaas, P., Lachlan, K., Jeste, S., Kolevzon, A., Loth, E., Harris, J., Speer, L., Pepper, T., Anthony, K., Graglia, J. M., Delagrammatikas, C., Bedrosian-Sermone, S., Beekhuyzen, J., Smith-Hicks, C., Sahin, M., Eng, C., Hardan, A. Y., & Uljarevic, M. (2023). Development of informant-report neurobehavioral survey scales for PTEN hamartoma tumor syndrome and related neurodevelopmental genetic syndromes. Am J Med Genet A, 191(7), 1741-1757. https://doi.org/10.1002/ajmg.a.63195 Frazier, T. W., Crowley, E., Shih, A., Vasudevan, V., Karpur, A., Uljarevic, M., & Cai, R. Y. (2022). Associations between executive functioning, challenging behavior, and quality of life in children and adolescents with and without neurodevelopmental conditions. Frontiers in Psychology. https://doi.org/10.3389/fpsyg.2022.1022700 Frazier, T. W., Dimitropoulos, A., Abbeduto, L., Armstrong-Brine, M., Kralovic, S., Shih, A., Hardan, A. Y., Youngstrom, E. A., Uljarevic, M., & Quadrant Biosciences - As You Are Team. (2023). The Autism Symptom Dimensions Questionnaire: Development and psychometric evaluation of a new, open-source measure of autism symptomatology. Developmental Medicine and Child Neurology. https://doi.org/10.1111/dmcn.15497 Frazier, T. W., Dimitropoulos, A., Abbeduto, L., Armstrong-Brine, M., Kralovic, S., Shih, A., Hardan, A. Y., Youngstrom, E. A., Uljarevic, M., Womack, R., Wolf, D., Chappell, N., & Verbal Beginnings Team. (2024). Psychometric Evaluation of the Autism Symptom Dimensions Questionnaire (ASDQ). Developmental Medicine and Child Neurology. Frazier, T. W., Hyland, A. C., Markowitz, L. A., Speer, L. L., & Diekroger, E. A. (2020). Psychometric evaluation of the revised child and family quality of life questionnaire (CFQL-2). Research in Autism Spectrum Disorders, 70. https://doi.org/https://doi.org/10.1016/j.rasd.2019.101474 Frazier, T. W., Khaliq, I., Scullin, K., Uljarevic, M., Shih, A., & Karpur, A. (2022). Development and psychometric evaluation of the open-source challenging behavior scale. Journal of Autism and Developmental Disabilities. https://doi.org/https://doi.org/10.1007/s10803-022-05750-5 Frazier, T. W., Krishna, J., Klingemier, E., Beukemann, M., Nawabit, R., & Ibrahim, S. (2017). A Randomized, Crossover Trial of a Novel Sound-to-Sleep Mattress Technology in Children with Autism and Sleep Difficulties. J Clin Sleep Med, 13(1), 95-104. https://doi.org/10.5664/jcsm.6398 Frazier, T. W., Busch, R. M., Klass, P., Crowley, E., Lachlan, K., Jeste, S., Kolevzon, A., Loth, E., Harris, J., Pepper, T., Anthony, K., Graglia, J. M., Helde, K., Delagrammatikas, C., Bedrosian-Sermone, S., Smith-Hicks, C., Sahin, M., Eng, C., Hardan, A. Y., . . . Uljarevic, M. (2024). Quantifying Neurobehavioral Profiles across Neurodevelopmental Genetic Syndromes and Idiopathic Neurodevelopmental Disorders. Developmental Medicine and Child Neurology. https://doi.org/https://doi.org/10.1111/dmcn.16112 Uljarevic, M., Cai, R. Y., Hardan, A. Y., & Frazier, T. W. (2022). Development and validation of the Executive Functioning Scale. Front Psychiatry, 13, 1078211. https://doi.org/10.3389/fpsyt.2022.1078211 Uljarevic, M., Spackman, E. K., Cai, R. Y., Paszek, K. J., Hardan, A. Y., & Frazier, T. W. (2022). Daily living skills scale: Development and preliminary validation. Frazier, T. W., Helton, M., Akouri, C., Chetcuti, L., & Uljarevic, M. (2025). Identifying reliable change in outcome assessments for behavioral interventions. Behavioral Interventions, 40, e70007. https://doi.org/https://doi.org/10.1002/bin.70007 Resources CentralReach. (n.d.). AI Measures (AIM). https://centralreach.com
Interview recorded - 19th of February, 2026On this episode of the WTFinance podcast I had the pleasure of welcoming on Barry Eichengreen. Barry is a renowned economist and Professor of Economics and Political Science at the University of California, Berkeley, where he has taught since 1987. He is also the author of many books, including the upcoming book “Money Beyond Borders: Global Currencies from Croesus to Crypto”During our conversation we spoke about his thoughts on the economy, the K-shaped economy, geopolitical shift, move away from the US dollar, what it means for the future and more. I hope you enjoy!0:00 - Introduction1:08 - Overview of the economy2:18 - K-shaped economy3:41 - Geopolitical shift6:13 - Europe becoming a world power?9:23 - US currency12:53 - China be trusted?14:58 - Precious metals movements17:09 - Next reserve currencies?19:58 - US Dollar devaluing21:47 - Bifurcating currency world23:56 - Influence for writing the book?25:58 - Any surprises?28:00 - One message to takeaway?Barry Eichengreen is George C. Pardee & Helen N. Pardee Chair and Distinguished Professor of Economics and Political Science at the University of California, Berkeley, where he has taught since 1987. He is a Research Associate of the National Bureau of Economic Research (Cambridge, Massachusetts) and Research Fellow of the Centre for Economic Policy Research (London, England). In 1997-98 he was Senior Policy Advisor at the International Monetary Fund. He is a fellow of the American Academy of Arts and Sciences (class of 1997). Professor Eichengreen is the convener of the Bellagio Group of academics and economic officials and chair of the Academic Advisory Committee of the Peterson Institute of International Economics. He has held Guggenheim and Fulbright Fellowships and has been a fellow of the Center for Advanced Study in the Behavioral Sciences (Palo Alto) and the Institute for Advanced Study (Berlin). He is a regular monthly columnist for Project Syndicate. His books include The Populist Temptation: Economic Grievance and Political Reaction in the Modern Era (2018), How Global Currencies Work: Past, Present, and Future, with Livia Chitu and Arnaud Mehl, (2017), The Korean Economy: From a Miraculous Past to a Sustainable Future (Harvard East Asian Monographs) with Wonhyuk Lim, Yung Chul Park and Dwight H. Perkins, (2015), Renminbi Internationalization: Achievements, Prospects, and Challenges, co-edited with Masahiro Kawai, (2015), Hall of Mirrors: The Great Depression, The Great Recession, and the Uses-and Misuses-of History, (2015). He was awarded the Economic History Association's Jonathan R.T. Hughes Prize for Excellence in Teaching in 2002 and the University of California at Berkeley Social Science Division's Distinguished Teaching Award in 2004. He is also the recipient of a doctor honoris causa from the American University in Paris.Barry Eichengreen - Website - https://eml.berkeley.edu/~eichengr/X - https://x.com/B_EichengreenBook - https://press.princeton.edu/books/hardcover/9780691280530/money-beyond-borders?_glWTFinance - Instagram - https://www.instagram.com/wtfinancee/Spotify - https://open.spotify.com/show/67rpmjG92PNBW0doLyPvfniTunes - https://podcasts.apple.com/us/podcast/wtfinance/id1554934665?uo=4Twitter - https://twitter.com/AnthonyFatseas
Ukraine will emerge from this war with enormous debt. The conventional wisdom treats that as an obstacle: investors weigh it before committing capital, and the burden slows the recovery before it starts. Yuriy Gorodnichenko and Maurice Obstfeld of UC Berkeley argue the opposite. A thorough restructuring of Ukraine's war debts – including, for sufficiently large obligations, outright forgiveness – is not just politically defensible but economically essential for attracting private investment. The bill for rebuilding and growing Ukraine, Gorodnichenko estimates, is $40 billion a year: $20 billion to replace destroyed capital, $10 billion to stop Ukraine falling behind its Eastern European peers, and $10 billion to start closing the gap. Put that figure next to what Poland absorbed in FDI during its post-communist transition, or the €200 billion of Russian state assets currently immobilised in Euroclear, or the budgetary support Ukraine has been receiving since 2022 – and it looks achievable. The harder challenge, they argue, is not raising $40 billion. It is directing it: towards investment rather than consumption. Ukraine didn't grow in the post-Soviet era at the rate that its neighbours achieved. EU accession momentum and secure borders can be a signal to investors that this time the trajectory will be different.The research behind this episode:Gorodnichenko, Yuriy, and Maurice Obstfeld. 2026. "You Only Live Twice: Financial Inflows and Growth in a Westward-Facing Ukraine." Economic Policy: Papers on European and Global Issues, special issue: "What's Next for Ukraine?"To cite this episode:Phillips, Tim. 2025. "You Only Live Twice: Financial Inflows and Growth in a Westward-Facing Ukraine." Economic Policy: Papers on European and Global Issues (podcast).Assign this as extra listening — the citation above is formatted and ready for a reading list or VLE.About the guestsYuriy Gorodnichenko is a CEPR Research Fellow and Professor of Economics at the University of California, Berkeley, where he leads CEPR's Ukraine Initiative. His research spans monetary policy, fiscal policy, and the macroeconomics of growth and business cycles.Maurice Obstfeld is a CEPR Distinguished Fellow and Class of 1958 Professor of Economics at the University of California, Berkeley. He served as Chief Economist of the International Monetary Fund from 2015 to 2018, and as a member of the Council of Economic Advisers under President Obama from 2014 to 2015. He is also a Fellow of the Econometric Society and the American Academy of Arts and Sciences.Research cited in this episodeThe discussion of debt overhang draws on a body of work from the 1980s developing-country debt crises, notably the insight that for sufficiently indebted countries, debt reduction can increase the expected value of what creditors recover. Gorodnichenko and Obstfeld apply this framework directly to Ukraine's war debts, arguing that deep restructuring – supported by bilateral official creditors, many of whom are European – is a prerequisite for private investment to follow.The €200 billion figure for immobilised Russian central bank assets held at Euroclear is the basis for Obstfeld's proposal of a reparations loan that would give Ukraine immediate access to large-scale resources, with repayment contingent on Russian reparations. This is discussed in more detail in the related reading below.More in the "What's Next for Ukraine?" seriesThis episode is the first in a three-part series based on papers presented at the inaugural Economic Policy winter conference, Paris, December 2025. Episodes 2 and 3, on rebuilding and the labour market, are forthcoming.Related reading on VoxEUYou only live twice: A growth strategy for Ukraine — Gorodnichenko and Obstfeld's own VoxEU column summarising the key arguments in this paper: why $40 billion a year is achievable, what the policy levers are, and why the window matters.Euroclear and the geopolitics of immobilised Russian assets — The legal and financial context behind the €200 billion of Russian central bank assets frozen at Euroclear, and what it would take to use them for a reparations loan to Ukraine.Using the returns of frozen Russian assets to finance the victory of Ukraine — A VoxEU proposal for channelling the interest income generated by frozen Russian assets to finance Ukraine's needs, without requiring the more politically contested step of confiscating the assets themselves.Ukraine's recovery challenge — An earlier VoxEU overview of the reconstruction task: the scale of damage, the role of EU accession, and the two-phase approach to restoring growth.
Neurologic complications of hematologic disorders are frequently encountered in clinical practice and can involve both the central and peripheral nervous systems. Early recognition and appropriate management in collaboration with a hematologist are essential to reduce morbidity and mortality. In this episode, Kait Nevel, MD, speaks with Lauren Patrick, MD, and Mark Terrelonge, MD, MPH, authors of the article "Neurologic Complications of Hematologic Disorders" in the Continuum® February 2026 Neurology of Systemic Disease issue. Dr. Nevel is a Continuum® Audio interviewer and a neurologist and neuro-oncologist at Indiana University School of Medicine in Indianapolis, Indiana. Dr. Patrick is an assistant professor of neurology at the University of California, San Francisco, in San Francisco, California. Dr. Terrelonge is an associate professor of neurology at the University of California, San Francisco, in San Francisco, California. Additional Resources Read the article: Neurologic Complications of Hematologic Disorders Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @IUneurodocmom Full episode transcript available here Dr Nevel: Thick blood, thin blood. These are terms often used by patients and caregivers to describe some of the hematologic disorders that can lead to neurological diseases such as stroke. So, when should we consider a hematologic disorder as a potential cause for neurological conditions, such as stroke or neuropathy. Today I have the opportunity to interview Drs Lauren Patrick and Mark Terrelonge to learn more about neurologic complications of hematologic disorders in their recent article in Continuum. Dr Jones: This is Dr Lyell Jones, editor-in-chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Nevel: Hello, this is Dr Kate Nevel. Today I'm interviewing Drs Lauren Patrick and Mark Terrelonge about their article on neurologic complications of hematologic disorders. This article appears in the February 2026 Continuum issue on neurology of systemic disease. Welcome to the podcast, and please introduce yourself to the audience. Dr Patrick: Thank you for having us. We're both thrilled to be here. I'm Lauren Patrick, a vascular neurologist and assistant professor at the University of California, San Francisco, and program director for the Vascular Neurology Fellowship here. Dr Terrelonge: And I'm Mark Terrelonge, I'm an associate professor of neurology and neuromuscular medicine here at UCSF and one of the associate program directors for the adult neurology residency. Nice to meet you. Dr Nevel: Nice to meet you both. Really looking forward to getting into your article and learning more. So, to kind of kick us off, I always like to ask what do you think is the most important takeaway from your article for the practicing neurologist? And maybe since there are two of you and I suspect you covered slightly different aspects of this article, maybe you could give us two most important takeaways. Dr Patrick: Sure. I think the biggest takeaway is to keep hematologic disorders on the differential when evaluating patients with neurologic symptoms. Conditions like sickle cell disease, myeloproliferative neoplasms, or plasma cell dyscrasias and paraproteinemia can cause strokes or peripheral neuropathies, and many have specific and targetable treatments. The early recognition and collaboration with our hematology colleagues can truly change patient outcomes, whether that's by initiating cytoreductive therapy, managing thrombocytopenia, or optimizing antithrombotic therapy. Dr Nevel: Great. So, this is a really big and diverse topic. As always, I'm going to urge our listeners to read the article because there is a lot of really good stuff in your article that we just don't have time to get into during this interview today. But you cover a lot of different hematological disorders and how they can cause neurological complications. One of the major neurological complications of hematological disorders is cerebral vascular events. So, I'm hoping, Warren, that you can walk us through a little bit. When should we consider workup of potential hematologic disorder as a cause when we see a patient with ischemic stroke, because certainly not all patients with ischemic stroke should be getting a broad hematological disorder work up. So how can we kind of identify early on that there might be something else at play? Dr Patrick: Absolutely, great question. So, in many cases, the underlying hematologic disorder is already known, such as sickle cell disease or polycythemia vera. But sometimes stroke is the initial presentation or manifestation of the disease. So red flags can include young age, recurrent cryptogenic strokes or thrombosis, and unusual locations like the cerebral venous system. Laboratory clues such as unexplained erythrocytosis, thrombocytosis, thrombocytopenia, or hemolytic anemia should raise suspicion for an occult hematologic disorder. In the setting of acute illness, immune-mediated or heparin-induced thrombocytopenia or thrombotic microangiopathies should be suspected in patients that have hemorrhagic and or thrombotic complications, particularly when relevant lab disturbances are present. Acquired thrombophilia such as anti-phospholipid antibody syndrome should be considered in young patients with autoimmune disease, prior venous or arterial thrombotic complications, or pregnancy morbidity. Now, these are rare causes overall, but they're important to catch because the management can differ dramatically from our typical stroke care. Dr Nevel: Great. And what are some of the most common inherited or acquired thrombophilias and when should we be sending these labs? Dr Patrick: The hematologic causes really account for small minority of arterial strokes approximately one to two percent, but among those, sickle cell disease, anti-phospholipid antibody syndrome and the myeloproliferative neoplasms are the most common. Timing of testing is key. So, the genetic thrombophilia panels can be drawn at presentation, but lab values such as protein C, protein S, and antithrombin levels may be falsely low during acute thrombosis, so they're often repeated weeks later. Similarly, for anti-phospholipid antibody testing that should be done at presentation and when positive, confirmed at twelve weeks, since transient positivity can occur with affections or acute events. So, in patients that are already anticoagulated for anti-phospholipid antibody syndrome, testing becomes particularly tricky, especially with lupus anticoagulant assays. Some results need to be interpreted carefully or repeated when feasible. The main message is to collaborate early with our hematology colleagues to guide the timing and interpretation of these studies. Dr Nevel: Yeah, wonderful. Thank you. I'll ask some similar questions about neuropathy. So when should we consider an underlying hematologic disorder as being the cause for someone's neuropathy? Dr Terrelonge: So, luckily for a neurologist, then serum protein electrophoresis or an SPEP is already a part of the first pass evaluation for even the most common neuropathies we see, technically already considered every time we do an evaluation. However, we do know that most neuropathies progress very slowly and don't really lead to significant limitations in patient activities of daily living. And for those, the initial workup step, you may not need to do any additional search for any hematologic diseases after that first step. Within patients who start to have more unusual features with their neuropathy, including a rapid progression, early proximal weakness, significant and extremely painful neuropathies, significant ataxia, or new tremor or anything that's kind of outside of the garden variety neuropathy, then you should start to think about a hematologic cause. Additionally, if a patient already has a known hematologic malignancy or process before their neuropathy, there should be some form of assessment to see through exam or electrodiagnostically if the two are correlated. I do have to add one caveat, though, and that's just because someone has a hematologic malignancy or a paraprotein seen in their blood, their neuropathy and the neurologic syndrome don't necessarily have to be causally related. So, we have to do some additional testing to determine if the patient's presentation of the paraprotein are actually linked. Dr Nevel: Can you walk us through a little bit how we determine if they're associated or just coincidental? Dr Terrelonge: Yeah. So, for some of the proteins, there's a specific phenotype that will come with the specific protein. For example, an anti MAG proteinopathies or MAG standing for a myelin associated glycoprotein, it usually leads to a distal sensor and motor polyneuropathy where the most distal portions of nerves are affected. So, in that case, people might notice that they have numbness and weakness in their toes and their fingers, and it doesn't follow that typical length dependent pattern. So, in that case, if you have the anti mag neuropathy and the electrodiagnostic signature of an anti mag neuropathy along with the symptoms, you're more likely to think that the two are related then if not. Dr Nevel: Great. Thank you. And I was hoping you could speak a little bit more about amyloidosis just because I think that that's one that can be really tricky to diagnose. And I see patients, you know, have sometimes more drawn out evaluations or see multiple providers before a diagnosis is reached. So, can you speak a little bit more to how we diagnose amyloidosis in relationship to neuropathy or other neurological conditions and when we should push for more invasive testing like a nerve biopsy? Dr Terrelonge: So, amyloidosis certainly is a tricky diagnosis. I've been tricked by it and I think most of my neuromuscular colleagues have probably been tricked by it at least once. It's a hard diagnosis to make is it usually requires a pretty high index of suspicion, and also requires a tissue diagnosis to cinch. There're some patients who will come in with a prior history of amyloidosis and they're a little bit easier to figure out if the neuropathy is related. Maybe it's started in their heart or their kidney first and then you can just see if the type of amyloid they have usually deposits in nerve, and that may be enough. But if there's any diagnostic uncertainty, you could go forward with tissue biopsy. But it's patients in which the neuropathy is the first symptom that amyloidosis can be especially tricky to diagnose. It's a primarily light chain disease. So, if you do only an SPEP as a part of your initial neuropathy evaluation, you could miss it. But usually, the patients will have either a severely painful neuropathy, early autonomic dysfunction, or really prominent bilateral carpal tunnel syndrome. So, if they have any of those, usually we'll add in an amyloid workup as a part of that of the rest of the workup, which would include both light chain evaluations to see if there's any increase in Lambda or Kappa light chains and then also biopsy. Biopsy can be of the skin or fat pad first, which have reasonable sensitivity for picking up disease, but they're not necessarily a hundred percent. So if the suspicion remains high in those cases, a nerve biopsy should be considered. And the reason why this is important is that the chemotherapeutic agents that we have now can actually help arrest a lot of these diseases and stop further organ involvement. So, if you think about it, it is important to keep pushing and looking until you find it. Dr Nevel: Thank you so much for that. And a follow up question to that, once patients are started on appropriate therapy, the diagnosis is made, chemotherapy is started, what's the typical clinical course that you see in terms of their neuropathy? Do you ever see improvement or is it arrest of worsening? Dr Terrelonge: Usually for amyloid, there is an arrest of disease, but in some patients, they could have some improvement, not necessarily a dramatic improvement, but some patients could see some reversal of symptoms. That may not necessarily be because nerves injured nerves are regrowing, but because of reorganization of nerves to muscle, they could have some strength increases or at least less pain. Dr Nevel: Yeah, thank you. So, when should we involve a hematologist in aiding in the evaluation of patients we suspect may have an underlying hematological disorder? You guys really outlined very nicely in your article some of the laboratory workup or other workup like you just talked about with amyloidosis. But at what point in that workup should we reach out to our hematology colleagues? Dr Patrick: I would say almost always. So, these disorders are inherently multi-system and benefit from early co-management. In acute sickle cell stroke, for example, hematology helps direct emergent exchange transfusion. For myeloproliferative disorders they guide cyto reduction and long term antithrombotic strategy. And for antibody mediated or plasma cell disorders, hematology determines disease specific therapies. So, neurology may help with identifying the presentation, but the definitive management is almost always shared with our hematology colleagues. Dr Nevel: And as you both have mentioned that a lot of times in these cases, their hematologic disorder may be already known before they present with their neurological symptoms. So, I imagine obviously in those cases that a hematologist hopefully is already heavily involved in their care. What do you think is the most difficult aspect of identifying and diagnosing patients with neurologic illness as having an underlying hematological disorder? Dr Patrick: The hardest part is maintaining a high index of suspicion, especially since hematologic causes account for a very small minority of arterial strokes. Most strokes are from traditional vascular risk factors like you mentioned, or cardio embolism, so it's easy to stop diagnostic evaluation after standard studies have been performed. An example of a challenging case is a patient that's young, they've had recurrent cryptogenic stroke, and they could have antiphospholipid antibody syndrome, but it can be easy to miss if their antibody titers are borderline or if they're already anticoagulated, which would complicate retesting. So, it's about balancing the urge to over-test with recognizing the few cases where identifying A hematologic cause truly changes that management. Dr Terrelonge: And then on the neuropathy side, probably the hardest part is deciding what's causal and what's coincidence. Monoclonal gammopathy of unknown significance, or MGUS, is really common in older adults, so not every M-spike on an SPEP explains a neuropathy. And even sometimes there's times when the neurologic picture will develop a little bit faster than the hematologic one. So, it's hard to put the two together. Dr Nevel: Yeah. What's the most rewarding aspect of taking care of patients with complications from their hematologic disorders? Dr Patrick: It's deeply rewarding when a targeted diagnosis leads to a tangible improvement in that patient's care. For example, identifying A cryptogenic stroke is being due to myeloproliferative neoplasm or an inherited thrombophilia allows us to move from empiric treatment to possible disease specific strategy. It's really gratifying to give patients that clarity, to give them a diagnosis and in some cases prevent future events. Dr Terrelonge: Agreed. And even on the neuropathy side, almost all of the neuropathies that are hematologically related are treatable. So, it's so satisfying whenever you have a patient with say an anti-MAG neuropathy or Waldenström can start the patient on therapy, and you can see someone who's been having a progressive decline to stability and in those cases sometimes even significant recovery. Dr Nevel: Yeah, absolutely. Very rewarding when you can identify the problem and make it better. That's what it's all about. So, what are the future areas of research in this area? What do we still need to learn? Dr Patrick: There's still a lot to learn. I think we need better data on the safety of acute reperfusion therapy and antithrombotic agents, particularly in patients that are at dual risk for bleeding and thrombosis. Other examples, secondary prevention strategies and anti-phospholipid antibody syndrome. What's the best target INR? Do you add aspirin to warfarin or not? All of that is often left up to expert opinion. What's the best management for adults with sickle cell stroke? There are many open questions there. A lot of the protocols that we have in place for sickle cell patients that are adults as derived from pediatric literature and there's vast potential in terms of disease modifying therapies, especially in the fields of sickle cell disease and amyloidosis. And we'll need to reassess how those treatments may change neurologic outcomes. Dr Terrelonge: I think on the neuropathy side that having some form of new biomarkers to help us clearly know of the neuropathy and that hematologic illness are associated would be very helpful. On the treatment side, a lot of this is really being driven by the hematology space, but new therapies that treat hematologic plasma cell disorders, including some of the new BTK inhibitor, may be incorporated relatively soon into the algorithm for how we treat many of our patients. I'm excited to see what's to come from this. Dr Nevel: Wonderful. Thank you so much for sharing your knowledge with us today. I know I've certainly learned a lot by reading your article and through our discussion today. Highly encourage our listeners to read your wonderful article, which is a very thorough review of hematologic disorders and neurological complications. Again, today I've been interviewing Dr Lauren Patrick and Dr Mark Terrelonge on their article Neurologic Complications of Hematologic Disorders, which appears in the February 2026 Continuum issue on Neurology of Systemic Disease. Please be sure to check out Continuum Audio episodes from this and other issues. And as always, thank you so much to our listeners for joining today, and thank you so much to Lauren and Mark. Dr Terrelonge: Yeah, thank you so much for having us. Dr Patrick: Thank you so much for having us and for highlighting this topic. We hope the issue encourages clinicians to think broadly about hematologic causes of neurologic disease and to continue collaborating closely with our hematology colleagues. It's a complex but very fascinating intersection for both of our fields. Dr Monteith: This is Dr Teshamae Monteith, associate editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in depth and clinically relevant information important for neurology practitioners. Use this link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/AudioCME. Thank you for listening to Continuum Audio.
In this bonus episode, Nobel Prize-winning economist Daron Acemoglu joins Sam to challenge some of the most common assumptions about artificial intelligence's future. Drawing on his book Power and Progress, Daron argues that technology doesn't have a fixed destiny — and that today's choices will determine whether AI boosts workers or simply accelerates automation and inequality. He makes a case for focusing on new tasks that complement human skills, rather than replacing them, and warns that current incentives push AI toward centralization and automation by default. The conversation tackles productivity myths, reliability risks, and why regulation should proactively steer AI toward social good. Read the episode transcript here. Guest bio: Daron Acemoglu is an institute professor at MIT, faculty codirector of the James M. and Cathleen D. Stone Center on Inequality and Shaping the Future of Work, and a research affiliate at MIT's newly established Blueprint Labs. He is an elected fellow of the National Academy of Sciences, American Philosophical Society, the British Academy of Sciences, the Turkish Academy of Sciences, the American Academy of Arts and Sciences, the Econometric Society, the European Economic Association, and the Society of Labor Economists. He is also a member of the Group of Thirty. He has authored six books, including Power and Progress: Our Thousand-Year Struggle Over Technology and Prosperity with Simon Johnson. His work in economics has been recognized around the world, notably with the Nobel Prize in economic sciences, along with co-laureates Johnson and James A. Robinson, in 2024. *Please take our listener survey: mitsmr.com/podcastsurvey It's short — we promise! — and all respondents will receive a free MIT SMR article collection, "Maximizing the Value of Generative AI." Me, Myself, and AI is a podcast produced by MIT Sloan Management Review and hosted by Sam Ransbotham. It is engineered by David Lishansky and produced by Allison Ryder. We encourage you to rate and review our show. Your comments may be used in Me, Myself, and AI materials. ME, MYSELF, AND AI® is a federally registered trademark of Massachusetts Institute of Technology. All rights reserved.
In this Q&A episode of our neonatal opioid withdrawal syndrome (NOWS) series, we address challenging and nuanced clinical questions surrounding withdrawal, toxicology testing, and newborn exposures. Our host, Paul Wirkus, MD, FAAP, and guest Camille Fung, MD, review the early signs of withdrawal and discuss the process of obtaining consent for neonatal toxicology screening, clarifying when testing is considered diagnostic and how results may have reporting implications.We also explore common clinical scenarios, including the impact of maternal fentanyl administered via epidural on newborn toxicology results, and how in utero SSRI exposure may present with symptoms such as apnea, posturing, or seizure-like activity. The conversation further examines the effects of prenatal THC exposure, addressing common misconceptions, potential neonatal impacts, and the persistence of THC in breastmilk.Throughout the discussion, the emphasis remains on careful clinical assessment, clear communication with families, and a nonjudgmental, evidence-based approach to care.Have a question? Email questions@vcurb.com.For more information about available credit, visit vCurb.com.ACCME Accreditation StatementThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Colorado Medical Society through the joint providership of Kansas Chapter, American Academy of Pediatrics and Utah Chapter, AAP. Kansas Chapter, American Academy of Pediatrics is accredited by the Colorado Medical Society to provide continuing medical education for physicians. AMA Credit Designation StatementKansas Chapter, American Academy of Pediatrics designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Brian Moreland recently made waves on Broadway as a producer of the groundbreaking revival of Othello, starring Denzel Washington and Jake Gyllenhaal, and directed by Tony Award winner Kenny Leon. The production shattered box office records, becoming the highest-grossing play revival in global history. His impressive repertoire includes the Broadway revival of The Wiz, starring Wayne Brady and Deborah Cox; August Wilson's The Piano Lesson, directed by LaTanya Richardson Jackson and starring Samuel L. Jackson, Danielle Brooks, and John David Washington — which became the highest-grossing revival of the season; The Lifespan of a Fact, featuring Cherry Jones, Daniel Radcliffe, and Bobby Cannavale; Sea Wall / A Life, a moving dual narrative with Jake Gyllenhaal and Tom Sturridge; and The Sound Inside, a compelling drama headlined by Mary-Louise Parker. Hailing from California, Brian now calls New York City home, where he continues to shape the cultural landscape through his visionary storytelling and unwavering passion for the performing arts. His dedication to accessibility and equity in theatre is reflected in his active role with the Theatre Development Fund (TDF), an organization committed to expanding access to live performance. A respected leader within the industry, Brian serves on the Board of Governors of The Broadway League, where he also co-chairs the Multicultural Task Force, advocating for greater diversity and inclusion across the theatre community. He also holds leadership roles as a Board Director for NYC Tourism and Conventions, a Trustee of Broadway Cares/Equity Fights AIDS, and a Trustee of The American Academy of Dramatic Arts, where he helps support and guide the next generation of performing artists. In recognition of his impactful contributions, Brian has been honored with the Board of Directors Distinguished Service Award by the Audelco Awards and acknowledged by the Theatre Communications Group (TCG) for his continued service to the field. Through his compelling productions and steadfast leadership, Moreland has established himself as a transformative force in contemporary theatre. His work not only entertains but also uplifts and challenges audiences, enriching the cultural narrative with stories that reflect the depth, diversity, and complexity of the human experience.Joe Turner's Come and Gone is lead produced by Brian Anthony Moreland with casting by ARC Casting. 101 Productions, Ltd. is serving as general managers.For additional information, please sign up at www.JoeTurnerBway.comConnect with Brian Anthony Moreland:Website: https://www.bmorenowproductions.com/ Instagram: https://www.instagram.com/therealbrianmoreland/?hl=en TurnKey Podcast Productions Important Links:Guest to Gold Video Series: www.TurnkeyPodcast.com/gold The Ultimate Podcast Launch Formula- www.TurnkeyPodcast.com/UPLFplusFREE workshop on how to "Be A Great Guest."Free E-Book 5 Ways to Make Money Podcasting at www.Turnkeypodcast.com/gift Ready to earn 6-figures with your podcast? See if you've got what it takes at TurnkeyPodcast.com/quizSales Training for Podcasters: https://podcasts.apple.com/us/podcast/sales-training-for-podcasters/id1540644376Nice Guys on Business: http://www.niceguysonbusiness.com/subscribe/The Turnkey Podcast: https://podcasts.apple.com/us/podcast/turnkey-podcast/id1485077152
This week's Recast is from April 2020. Why This Episode Matters Now:In 2022, the war in Ukraine revealed something our partners had been experiencing but we hadn't fully articulated: the traditional model of intact, homogeneous teams wasn't sufficient for the emerging operational environment. Individuals with diverse expertise, geography, language, and allegiances needed to rapidly converge into what we call Tactical Swarms—heterogeneous cross-functional units that form, solve emergent problems, and disperse.Our recent white paper, The Fourth Generation of Military Special Operations Selection & Assessment, explores this evolution in depth. But six years ago, Preston laid the foundational concepts in this conversation with Coleman.What the Research Shows:Many operators who excelled at teamwork—performing with known, homogeneous teams—struggled with teaming: the ability to rapidly build cohesion within heterogeneous groups. This episode examines why routine versus critical communication and field observations across special operations, emergency medicine, and other high-stakes environments. In this episode, Preston and Coleman describe how tactical swarms and X teams differ from traditional team structures, and they distinguish between routine and critical communication and when teams must shift between them. Recent Research:Cline, P.B. (2026). The Fourth Generation of Military Special Operations Selection Assessment: A Community of Praxis [White paper]. Mission Critical Team Institute. DOI 10.13140/RG.2.2.28255.73121. https://missioncti.com/wp-content/uploads/2026/02/The-Fourth-Generation-of-Military-Special-Operations-Selection-Assessment_Final_2-Feb-26.pdf Falk, D., Cline, P., Donegan, D., & Mehta, S. (2023). A Novel Framework for Routine Versus Critical Communication in Surgical Education—Don't Take It Personally. Journal of the American Academy of Orthopaedic Surgeons, 31(3), 115–121. https://doi.org/10.5435/JAAOS-D-22-00912 https://missioncti.com/wp-content/uploads/2023/08/FINAL-A-Novel-Framework-for-Routine-Versus-Critical.pdf If you find value in this discussion, the best way to support our work and stay up to date on future episodes is to subscribe and leave us a quick rating or review. It helps us reach more people who need to hear these conversations.This episode contains a term that may be offensive; it is used to describe gendered communication dynamics. We have included it to accurately represent the event, and it is intended for educational purposes only.
Manual therapy is one of those topics that seems to quickly descend to polarised debates in musculoskeletal rehabilitation. Today, we're talking about what manual therapy looks like and does in the 2020s. Dr Jodi Young explains the mechanisms of manual therapy, the typical effects and why you might think about adding manual therapy as another tool in your physical therapy toolkit. Dr Young is the Director of Research for the Doctor of Science in Physical Therapy program at Bellin College in Green Bay, Wisconsin, where she mentors doctoral clinicians and helps turn clinical and educational research questions into meaningful, publishable research. She is also a fellow of the American Academy of Orthopaedic Manual Physical Therapists. ------------------------------ RESOURCES Modern definition and description of manual therapy: https://pubmed.ncbi.nlm.nih.gov/38457654/ Modern way to teach and practice manual therapy: https://pubmed.ncbi.nlm.nih.gov/38773515/ Living review of manual therapy mechanisms: https://pubmed.ncbi.nlm.nih.gov/40100908/ Unravelling the mechanisms of manual therapy: https://www.jospt.org/doi/10.2519/jospt.2018.7476 Developing manual therapy frameworks: https://www.jospt.org/doi/10.2519/josptopen.2023.0002 Integrating person-centred concepts and modern manual therapy: https://www.jospt.org/doi/full/10.2519/josptopen.2023.0812 How do patients believe manual therapy works? https://www.jospt.org/doi/10.2519/josptopen.2025.0149 Does it matter how you apply spinal manipulation? JOSPT Insights ep 221: https://pod.link/1522929437/episode/NmM0MTg4OGMtODMwMi00ZTA3LTg1NzUtYjY2ZjBiMThiZGUy
Send a textAbout Azinda MorrowDr. Azinda Morrow is currently an Associate Optometrist at Silicon Valley Eyecare Optometry & Contact Lenses in Santa Clara, CA. She earned her Doctor of Optometry degree from SUNY College of Optometry in 2017 and completed her residency in Cornea and Contact Lenses at the Illinois College of Optometry in Chicago, IL in 2018. After completion of her residency, she was an Assistant Clinical Professor at the SUNY College of Optometry / University Eye Center and responsible for clinical supervision of students and residents in both the Cornea / Contact Lens and Myopia Management clinics. In addition, she taught in pre-clinical laboratories and was involved in clinical research. Now in private practice, Dr. Morrow continues to provide full-scope care to patients of all ages, as well as continuing her passion of caring for patients with specialty contact lens and myopia management needs. Dr. Morrow is also a fellow of the American Academy of Optometry, and a member of the American Optometric Association.---Thanks to TEEM for their support of this episode. If you're considering or have ever considered getting a virtual team member for your practice check out hiredteem.com, mention The Myopia Podcast when signing up for a $250 dollar discount off of your first month's teem member.https://hireteem.com/myopia-podcast/
What happens when you turn the microphone on the man who's spent years behind it? In this episode of the NAIL-IT podcast, Rana and Bav get Payman Langroudi — host of Dental Leaders and Clinical Director at Enlighten — firmly in the hot seat. It's a wide-ranging, refreshingly candid conversation that moves from the origins of Enlighten and the relentless pursuit of world-class quality to the very real mental health pressures that underpin life in dentistry. Payman reflects on leaning into his strengths, trusting his instincts, and why, after 320 episodes, the Dental Leaders podcast has become the thing he's most proud of. Find Rana on Instagram at @drranaalfalaki, and on Facebook and LinkedIn as Dr Rana Al-Falaki. Follow Bav on Instagram at @drbav83. You can also follow the NAIL-IT podcast at @nailit_podcast.In This Episode00:01:05 — Introductions and the Dental Leaders origin story00:02:10 — Why Payman started a podcast — and what it's become00:05:20 — Leaning into strengths, owning your quirks00:07:00 — Starting Enlighten at 28 and the philosophy of doing one thing brilliantly00:10:25 — The sacrifices behind world-class quality00:14:10 — Being number two — and the decision to become the best00:16:15 — Favourite quote: Oscar Wilde and the art of being yourself00:20:25 — Identity, self-awareness and shedding the layers00:21:50 — Dentistry as a kingdom — and why practices are anything but the same00:23:10 — Mental health in dentistry: burnout, suicide and the stress bucket00:27:40 — The emotional drain of being "on show" all day00:30:20 — Kids, careers and the realities of dentistry as a profession00:35:40 — Knowing yourself before you can lead others00:36:10 — Intuition as a leadership skill — and how to train itAbout Dr Rana Al-Falaki and Dr Bhavin PatelDr Rana Al-Falaki is a periodontist and internationally recognised pioneer in the use of lasers in periodontal treatment, having presented her research to audiences from the British Society of Periodontology to the American Academy and European Federation. After pushing herself to the point of chronic illness in pursuit of excellence, she channelled that experience into developing the NAIL-IT programme — a performance and leadership system built around optimising energy and helping dental professionals truly thrive. Dr Bhavin Patel is a dentist and educator who ran a practice on Wimpole Street for nearly eight years before stepping back to prioritise family life. Together, they host the NAIL-IT podcast — a show dedicated to helping dental professionals live fully, lead better, and laugh more.
In this episode, Dr. Sarah Jebreil (@sarahjebreildds), an Accredited Member of the American Academy of Cosmetic Dentistry, shares her inspiring journey from working in her father's practice to becoming a renowned cosmetic dentist with her own brand. She discusses the significance of accreditation and how it has helped her achieve clinical excellence and build a reputable practice.KEY TOPICSDr. Sarah Jebreil's journey from her father's practice to creating her own brandThe prestigious AACD accreditation and its impact on her careerStrategies for young dentists to establish their own practicesThe importance of continuous learning and innovation in cosmetic dentistryBalancing patient satisfaction with clinical precisionRESOURCES & LINKSAACDFacially Generated Treatment Planning by Frank SpearSarah Jebreil on InstagramAmerican Academy of Cosmetic DentistryCONNECT WITH DR. SARAH JEBREIL:InstagramMessage on social mediaCHAPTERS00:00 - Introduction to Dr. Sarah Jebreil01:14 - Growing up in her father's practice02:44 - Achieving AACD accreditation05:17 - Building her own practice and brand09:47 - Practice management and team building12:20 - Setting fees and overcoming imposter syndrome14:46 - Managing patient expectations and satisfaction20:37 - Future trends in cosmetic dentistry_______Don't miss out on these deals: Prioritize your wellness—shop my daily essentials here: https://teethmatterpod.com/storeCOCOFLOSS - Use code TM20 to get 20% off https://cocofloss.com/ FIGS - Use referral code to get 20% off https://fbuy.io/figs/elliehalabianIf you want to join the conversation about the realities of dentistry, follow: Instagram: @_teethmatter LinkedIn: Ellie Halabian__________________________If you enjoy the podcast, subscribe and rate ⭐️. If you think a friend will enjoy it, please share it with them.
Join us in Vegas for Podjam 3! Subscribe and Watch Interviews LIVE : On YOUTUBE.com/StandUpWithPete ON SubstackStandUpWithPete Stand Up is a daily podcast. I book,host,edit, post and promote new episodes with brilliant guests every day. This show is Ad free and fully supported by listeners like you! Please subscribe now for as little as 5$ and gain access to a community of over 750 awesome, curious, kind, funny, brilliant, generous soul Peter J. Hotez, MD, PhD, is the founding dean of The National School of Tropical Medicine at Baylor College of Medicine in Houston, Texas, as well as director of the Texas Children's Hospital Center for Vaccine Development. He is an elected member of the Institute of Medicine of National Academies as well as the American Academy of Arts and Sciences. A pediatrician and an expert in vaccinology and tropical disease, Hotez has authored hundreds of peer-reviewed articles and editorials as well dozens of textbook chapters. www.peterhotez.org On YOUTUBE.com/StandUpWithPete ON SubstackStandUpWithPete Listen rate and review on Apple Podcasts Listen rate and review on Spotify Pete On Instagram Pete on Blue Sky Pete on Threads Pete on Tik Tok Pete on Twitter Pete Personal FB page Stand Up with Pete FB page
This week I'm talking to Nancy Rynes about her Near Death Experience.Nancy Rynes was riding her bicycle when a large SUV approached. The vehicle's driver, absorbed in texting while driving, plowed right into Rynes.Suffering from severe spinal and head injuries, Rynes knew she was dying. At that moment, she underwent the first of two life-changing near-death experiences—her consciousness split between her frightened, injured self laying on the road, and an impartial, peaceful observer-consciousness who watched as first responders fought to keep her alive. Her second, more lengthy near-death experience came days later, during the surgery that attempted to repair her traumatized spine.Rynes, a scientist and confirmed skeptic, was shown the wonders of Heaven, experiencing joy, love, and beauty on such a grand scale that she wept at its magnitude. She then met and spoke with a Being who gave her insights into life, love, and the wonders of Spirit. After her tour of Heaven, she was returned to her body to begin the long, slow process of recovering from injuries her surgeon affirms should have killed her.In her book 'Awakenings from the Light', Rynes recounts the amazing sights of Heaven, and explains the remarkable insights into life she returned with to share with others. She was gifted with a second chance—a precious opportunity to bring a little bit of Heaven into her life on Earth. The wisdom she passes on could well change your life as well.BioMy friends call me "the atheist who went to Heaven."I would never have thought I would be writing a book about spirituality and near-death experiences since I spent my adult life as a scientist and skeptic. Born Roman Catholic, I became an atheist, and later an agnostic, beginning in my late teens when I went off to university to study geology and archaeology. While I started out my education as an artist (at Chicago's American Academy of Art), I went on to earn a degree in geology from Northern Illinois University, then attended the University of Colorado, Boulder, for Masters-level coursework. The sciences taught me to base my views on things I could measure, and since spiritual matters were not measurable, for me they did not exist.During most of my adult life, a part of me hoped there was something more than just physical reality, but I never saw evidence for it. The skepticism remained until January of 2014, when the Divine gave me a wake-up call: an opportunity to return to Spirit! Since my near-death experience, I have returned to a more spiritual and creative life based on the wisdom I learned in Heaven.In the past, I have been an archeological artist, geologist, data analyst, and science/technical writer. But then Heaven threw me a curveball, one I desperately needed. Now I am writing and teaching about my experience of the Divine, what happens when we die, and how we can bring a little bit of "Heaven" to our lives on Earth.https://www.amazon.com/Awakenings-Light-Lessons-Death-Experience-ebook/dp/B010MBT4QC https://www.pastliveshypnosis.co.uk/https://www.patreon.com/ourparanormalafterlifeMy book 'Verified Near Death Experiences' https://www.amazon.com/dp/B0DXKRGDFP Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Episode 516 / Hilary HarnischfegerHilary Harnischfeger (b. 1972, Melbourne, Australia) earned her MFA from Columbia University, New York (2003) and her BFA from the University of Houston, Houston, TX (2001). The artist has had work included in institutional exhibitions at the Fairfield University Art Museum, Fairfield, CT (2023); Nerman Museum of Contemporary Art, Overland Park, KS (2016); State University of New York at Purchase, Purchase, NY (2016); the FLAG Art Foundation, New York, NY (2014); MOCA Cleveland, Cleveland, OH (2013); American University Museum at the Katzen Arts Center, Washington, DC (2013); the American Academy of Arts and Letters, New York, NY (2013); Dallas Contemporary, Dallas, TX (2010); Ballroom Marfa, Marfa, TX (2005); Artists Space, New York, NY (2005); and the Contemporary Arts Museum Houston, Houston, TX (2002); among others. Harnischfeger has had recent solo exhibitions at Clear Sky Gallery, Brooklyn, NY (2021); Rachel Uffner Gallery, new York, NY (2021, 2015); Halsey McKay Gallery, East Hampton, NY (2014); and Front Gallery, Houston, TX (2012). In 2007, Harnischfeger was the recipient of the Maria Walsh Sharpe Foundation Space Program Award. Her work is in the permanent collection of the Cleveland Museum of Art, Cleveland, OH; the Nerman Museum, Overland Park, KS; the Everson Museum of Art, Syracuse, NY; and the Fairfield University Art Museum, Fairfield, CT. Harnischfeger lives and works in Brooklyn, NY.
SummaryIn this episode of The New Fangled Lawyer Podcast, Patrick Patino interviews Zack Port, a fellow attorney who has taken a unique approach to law practice by embracing mentorship and technology. They discuss the evolving role of lawyers in serving everyday people, the importance of building strong client relationships, and the balance between personal life and work. Zack shares his journey from law school to running a boutique personal injury firm, emphasizing the significance of storytelling and community engagement in legal practice. The conversation also touches on the challenges of navigating change in the legal field and the importance of maintaining a holistic identity as a lawyer.About ZackZack Port is a Minnesota personal injury attorney and co-founder of Betz & Port, which he started in 2022 with his partner Jim Betz. He helps people navigate the confusing and painfulaftermath of serious car crashes, with a particular focus on collision and trucking cases. Zack is active in the Minnesota Association for Justice, where he serves as Publications andCommunications Chair, and is also involved with the the American Academy of Trucking Attorneys. Outside of work, Zack is a girl dad, reluctant HOA president, and the worst bass player at his church. He enjoys abnormally long board games and reading science fiction.https://www.linkedin.com/in/zachary-port/, https://betzandport.com/zachary-port/, https://www.instagram.com/thelawport/TakeawaysZack Port emphasizes the importance of mentorship in law.The traditional mentor-mentee dynamic can be reversed.Building relationships with clients is crucial for success.Personal injury law allows for meaningful connections with clients.Technology can enhance law practice but should be used wisely.Choosing a simpler lifestyle can lead to greater focus.Client referrals are vital in building a practice.Defining an ideal client helps in targeting the right audience.Work-life balance is essential for avoiding burnout.Storytelling is a key skill for effective litigation.
Connecticut lawmakers pushed for a refundable child tax credit. House Bill 5134 calls for a fully refundable child tax credit of $600 per child for up to three children. It would be available to families that earn up to $100,000 for single filers and $200,000 for joint filers.We spoke with Molly Markowitz from the American Academy of Pediatrics; she's also a member of the CT Child Tax Credit Coalition.
Up in the middle of the night at 2:37 a.m. like clockwork? Toss and turn, desperately trying to slip into slumber? Eyes pop open at 4 a.m. though you'd really love to sleep in till at least 6? Are you just tired all the time? Welcome to the sleep syndrome of menopause–a common cluster of midlife sleep problems this week's guest Dr. Andrea Matsumura treats every day. We break down what's behind women's sleep woes, including sleep apnea, lifestyle factors, and of course menopause. She also shares her DREAM Method as a practical framework for getting a solid night's rest.Dr. Andrea Matsumura, MD, MS, FACP, FAASM is a board-certified sleep medicine physician, menopause expert, speaker, and founder of the D.R.E.A.M. Sleep Method™. Known as Sleep Goddess MD, she specializes in helping women optimize sleep, circadian rhythm, and health during midlife. She is board-certified in Internal and Sleep Medicine, trained at the University of Texas Health Science Center at San Antonio and Oregon Health & Science University, and previously built a women-focused sleep consult service at The Oregon Clinic. Dr. Matsumura currently serves as Medical Director at Cascadia Health, is a Fellow of the American Academy of Sleep Medicine, co-founder of the M/Power Menopause Collective, and a leader in the Sleep Is Good Medicine™ campaign. Her work has been featured in The New York Times, SHAPE, SELF, and CNN Underscored. You can learn more about her and her work at andreamatsumuramd.comResourcesYou Deserve to Get Good Sleep with Andrea Matsumura, MD (Episode 91)
Nearly 1,000 people in South Carolina have been infected in a measles outbreak that started in a largely unvaccinated community in October. Dr. Martha Edwards, president of the South Carolina chapter of the American Academy of Pediatrics, explains how this outbreak has spread so quickly.And, social justice groups are remembering the Rev. Jesse Jackson. We look at how his civil rights leadership led to some of the activism we see today with Bryan Stevenson, founder of the Equal Justice Initiative in Montgomery, Alabama.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy
Touching your toes, pulling your heel to your butt, stretching your calves by pushing against a wall—what if these classic stretches aren't helping the way you think they are? Discover what's really happening when you feel "tight" and the game-changing approach that will help you avoid injury and stay active for years and decades. Physical therapist Joanna Fisher is here to help us find what might serve us better than flexibility! LET'S TALK THE WALK! Join here for support, motivation and fun! Wellness While Walking Facebook page Walking to Wellness Together Facebook GROUP Wellness While Walking on Instagram Wellness While Walking on Threads Wellness While Walking on Twitter Wellness While Walking website for show notes and other information wellnesswhilewalking@gmail.com RESOURCES AND SOURCES (some links may be affiliate links) Dr. Joanna Fisher, PT, DPT, OCS, FAAOMPT* Website Instagram *Joanna is a licensed Doctor of Physical Therapy, an Orthopedic Clinical Specialist, and a Fellow of the American Academy of Orthopedic Manual Physical Therapists with advanced training in pelvic floor rehabilitation. Want to Level Up Your Mobility? Add Weights, nyt.com - has some mobility exercises More mobility move depictions to come! Follow us both on social media and check back here soon! HOW TO RATE AND REVIEW WELLNESS WHILE WALKING How to Leave a Review on Apple Podcasts on Your iOS Device 1. Open Apple Podcast App (purple app icon that says Podcasts). 2. Go to the icons at the bottom of the screen and choose "search" 3. Search for "Wellness While Walking" 4. Click on the SHOW, not the episode. 5. Scroll all the way down to "Ratings and Reviews" section 6. Click on "Write a Review" (if you don't see that option, click on "See All" first) 7. Then you will be able to rate the show on a five-star scale (5 is highest rating) and write a review! 8. Thank you! I so appreciate this! How to Leave a Review on Apple Podcasts on a Computer 1. Visit Wellness While Walking page on Apple Podcasts in your web browser (search for Apple Podcasts or click here) https://www.apple.com/apple-podcasts/ 2. Click on "Listen on Apple Podcasts" or "Open the App" 3. This will open Apple Podcasts and put in search bar at top left "Wellness While Walking" 4. This should bring you to the show, not a particular episode – click on the show's artwork 5. Scroll down until you see "Rating and Reviews" 6. Click on "See All" all the way to the right, near the Ratings and Review Section and its bar chart 7. To leave a written review, please click on "Write a Review" 8. You'll be able to leave a review, along with a title for it, plus you'll be able to rate the show on the 5-star scale (with 5 being the highest rating) 9. Thank you so very much!! OTHER APPS WHERE RATINGS OR REVIEWS ARE POSSIBLE Spotify Goodpods Overcast (if you star certain episodes, or every one, that will help others find the show) Castbox Podcast Addict Podchaser Podbean HOW TO SHARE WELLNESS WHILE WALKING Tell a friend or family member about Wellness While Walking, maybe while you're walking together or lamenting not feeling 100% Follow up with a quick text with more info, as noted below! (My favorite is pod.link/walking because it works with all the apps!) Screenshot a favorite episode playing on your phone and share to social media or to a friend via text or email! Wellness While Walking on Apple – click the up arrow to share with a friend via text or email, or share to social media Wellness While Walking on Spotify -- click the up arrow to share with a friend via text or email, or share to social media Use this universal link for any podcast app: pod.link/walking – give it to friends or share on social media Tell your pal about the Wellness While Walking website Thanks for listening and now for sharing! : ) DISCLAIMER Neither I nor many of my podcast guests are doctors or healthcare professionals of any kind, and nothing on this podcast or associated content should be considered medical advice. The information provided by Wellness While Walking Podcast and associated material, by Whole Life Workshop and by Bermuda Road Wellness LLC is for informational and entertainment purposes only. It is not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment, and before undertaking a new health care regimen, including walking. Thanks for listening to Wellness While Walking, a walking podcast and a "best podcast for walking"!
In today's podcast, we visit with Dr. Michael Repka, current president of the American Academy of Ophthalmology. Tune in to hear about AAO leadership efforts including advocacy, from Medicare to medical code values. Subscribe to the podcast: https://MayoClinicOphthalmology.podbean.com Follow and reach out to us on X and IG: @mayocliniceye
Charlotte and Jo go deep on jealousy, self-hatred, and vulnerability in a conversation that touches on A Separate Peace, The Go-Between, Beowulf, and more. Then the canny and intrepid Maya Binyam joins for a discussion about the category of little girlhood, ambiguity in fiction, and female desire.Maya Binyam is the author of Hangman. Her writing has appeared in the New Yorker, the Paris Review, Best American Short Stories, and elsewhere. She is a 2025 - 2026 Rome Prize Fellow at the American Academy in Rome. Please consider supporting our work on Patreon, where you can access additional materials and send us your guest and book coverage requests! Books discussed on all seasons of the podcast are aggregated here on Bookshop. Questions and comments can be directed to readingwriterspod at gmail dot com. Outro music by Marty Sulkow and Joe Valle.Charlotte Shane's most recent book is An Honest Woman. Her essay newsletter, Meant For You, can be subscribed to or read online for free, and her social media handle is @charoshane. Jo Livingstone is a writer who teaches at Pratt Institute.To support the show, navigate to https://www.patreon.com/ReadingWriters Hosted on Acast. See acast.com/privacy for more information.
In this episode with Airelle Giordano, we discuss two recent papers which cover the meniscus knee rehabilitation consensus. We explore:Patient eligibility for a MenisectomyRehabilitation post MenisectomyPrecautions and contraindications post menisectomyReturn to sport post meniscal repair
Episode 43 - Wendy Elverson - Managing Food Protein–Induced Allergic Proctocolitis (FPIAP)In this episode of Nutrition Pearls: the Podcast, co-hosts Megan Murphy and Bailey Koch speak with Wendy Elverson, RD, CSP, LDN about the latest research and best practice for managing infants with Food Protein-Induced Allergic Proctocolitis (FPIAP). Wendy is a registered dietitian who has specialized in clinical pediatric nutrition for more than 25 years. Currently, she is a Senior Clinical Nutrition Specialist at Boston Children's, with expertise in pediatric food allergies and feeding disorders. Wendy is a provider in several multidisciplinary, allergy-focused clinics, including the Atopic Dermatitis Center, the FPIES Clinic, and the EGID Clinic. Wendy has been an active member of CPNP since 2015 and has had many roles, currently serving on the NASPGHAN Public Education Committee. Wendy was the previous Chair of INDANA (International Network for Diet and Nutrition in Allergy) and is the current chair of the Nutrition Work Group of the Allied Health Assembly of the American Academy of Allergy, Asthma, and Immunology (AAAAI). She is a proud co-author of several publications, including a free resource for caregivers of children with milk and egg allergies, tolerant to baked milk and egg, Muffins and More: A Baked Milk and Baked Egg Recipe and Guidebook. Wendy was also the recipient of the 2025 CPNP Dietitian of Excellence Award. References: Mahoney, L. B., et al. (2025). Food protein-induced allergic proctocolitis: What do we know and where are we going? Current Treatment Options in Pediatrics, 11(1). https://doi.org/10.1007/s40746-025-00346-4Meyer, R., et al. (2025). An update on the diagnosis and management of non-IgE-mediated food allergies in children. Pediatric Allergy and Immunology, 36(3). https://doi.org/10.1111/pai.70060 Franco, C., Fente, C., Sánchez, C., Lamas, A., Cepeda, A., Leis, R., & Regal, P. (2022). Cow's Milk Antigens Content in Human Milk: A Scoping Review. In Foods (Vol. 11, Issue 12). https://doi.org/10.3390/foods11121783Gamirova, A., et al. (2022). Food proteins in human breast milk and probability of IgE-mediated allergic reaction during breastfeeding: A systematic review. Journal of Allergy and Clinical Immunology: In Practice, 10(5). https://doi.org/10.1016/j.jaip.2022.01.028Meyer, R., et al. (2023). WAO DRACMA guideline update VII: Milk elimination and reintroduction in cow's milk allergy diagnosis. World Allergy Organization Journal, 16(7). https://doi.org/10.1016/j.waojou.2023.100785Produced by: Corey IrwinNASPGHAN - Council for Pediatric Nutrition Professionalscpnp@naspghan.org
Ever catch yourself thinking, “I'm doing all the right things… so why do I still feel tired, foggy, or just off?” You're working out, trying to eat better, squeezing in sleep where you can, and yet your energy and longevity still feel like a question mark. If that sounds familiar, this episode of The Happy Hustle Podcast is going to land right where you need it.In this episode, I sit down with Dr. Joy Kong, a UCLA-trained, triple board-certified anti-aging physician, stem cell specialist, educator, and CEO. Dr. Joy is the founder of Chara Health and Chara Biologics, and she's deeply committed to advancing regenerative medicine in a way that is ethical, effective, and accessible. She also founded the American Academy of Integrative Cell Therapy, where she trains physicians around the world in stem cell therapies and cutting-edge regenerative practices.This conversation dives headfirst into stem cells, longevity, and what it actually means to optimize your health for the long game. Dr. Joy breaks down complex science in a way that feels grounded and practical. We explore how diet, exercise, sleep, and regenerative therapies can work together not just to help you live longer, but to live better. This episode matters because longevity isn't about chasing perfection or biohacking extremes. It's about understanding your body, making informed choices, and stacking small, intentional habits that compound over time.Here are a few powerful takeaways you'll walk away with.First, stem cells are not science fiction anymore. Dr. Joy explains what stem cell therapy actually is, how it works, and why it's becoming one of the most promising tools in regenerative medicine today. She also clears up common misconceptions and emphasizes the importance of quality, sourcing, and proper medical oversight.Second, longevity starts with the basics before the breakthroughs. While regenerative therapies are exciting, Dr. Joy reinforces that diet, movement, and sleep are still foundational. Stem cells and advanced treatments work best when your lifestyle is already supporting your body's natural healing processes.Third, education is the real power play in health. One of the most inspiring parts of Dr. Joy's journey is her commitment to teaching both patients and physicians. When you understand your options, you're no longer guessing or blindly outsourcing your health. You're making confident, informed decisions.Fourth, anti-aging is really about regeneration, not vanity. This episode reframes anti-aging as restoring function, reducing inflammation, and improving quality of life. It's not about looking younger. It's about feeling strong, clear, and capable for decades to come.Finally, serving others is the ultimate form of optimization. Dr. Joy's mission goes beyond medicine. Her work is rooted in service, integrity, and raising the standard of care across the industry. That alignment between purpose and profession is what truly defines a happy hustler.If you're curious about stem cells, longevity, or how to future-proof your health in a grounded, responsible way, this episode is absolutely worth your time. Do yourself a favor and listen to the full conversation. And if it resonates, share it with someone ready to take ownership of their health and hustle with intention.What does Happy Hustlin mean to you?Dr. Joy says if it's not fun, why are we doing this? So what's the whole point? You're spending eight hours a day at this place. I want you to have fun. So that's the happy hustling, but how to keep that state.Connect with Dr. JoyInstagramFacebookTiktokLinkedinTwitterYoutubeFind Dr. Joy on her website: https://joykongmd.com/ Connect with Cary!InstagramFacebookLinkedinTwitterYoutube Get a copy of his new book, The Happy Hustle, 10 Alignments to Avoid Burnout & Achieve Blissful BalanceSign up for The Journey: 10 Days To Become a Happy Hustler Online CourseApply to the Montana Mastermind Epic Camping Adventure“It's time to Happy Hustle, a blissfully balanced life you love, full of passion, purpose, and positive impact!”Episode Sponsors:If you're feeling stressed, not sleeping great, or your energy's been kinda meh lately—let me put you on to something that's been a total game-changer for me: Magnesium Breakthrough by BiOptimizers. This ain't your average magnesium—it's got all 7 essential forms that your body needs to chill out, sleep deeper, and feel more balanced. I take it every night and legit notice the difference the next day. No more waking up groggy or tossing and turning all nightIf you're ready to sleep like a baby, calm your nervous system, and optimize your recovery, go grab yours now at bioptimizers.com/happy and use code HAPPY10 for 10% OFF.
We've all seen it: the patient whose chart is “flagged” with a penicillin allergy, but when you dig into the history, the story doesn’t quite add up. Maybe it was a stomach ache in the 90s, or maybe they're just carrying a “inherited” allergy from a parent. In this episode of EM Pulse, we sit down with ED Clinical Pharmacist Haley Burhans to discuss why these labels are more than just a nuisance—they're a clinical liability—and how a simple tool can empower you to fix them on the fly. The Hidden Danger of the “Safe” Choice Choosing a non-beta-lactam antibiotic because of a questionable allergy label feels like the path of least resistance, but the data tells a different story. We explore how “playing it safe” can actually lead to: Worse Outcomes: Why second line antibiotics often mean higher treatment failure rates. The “Superbug” Factor: The surprising link between penicillin allergy labels and the rise of MRSA and VRE in our communities. The C. diff Connection: Why alternative choices might be setting your patient up for a much more difficult recovery. The Solution: The PEN-FAST Score How do you move from “I think this might not be a true allergy” to “I am confident this antibiotic is safe”? Haley introduces the PEN-FAST score, a validated scoring tool designed to risk-stratify patients based on a few key historical questions. The Mnemonic: We break down the PEN-FAST acronym so you know exactly which three questions to ask to risk-stratify your patient in seconds. IgE vs. The Rest: Learn to distinguish between the “true” dangerous hypersensitivity and the delayed reactions that shouldn’t stop you from using the best drug for the job. The “Amoxicillin Rash”: We dive into this common pediatric “gotcha.”, why many kids end up with a lifelong allergy label after a routine ear infection, and why it often has nothing to do with the drug itself. The Bottom Line: Patients with low PEN-FAST scores are considered low risk, making an oral challenge under observation in the ED a reasonable option. Higher scores may require shared decision-making or referral. Why the ED is the Perfect Place for a “Challenge” Delabeling isn’t just for the allergist’s office. We argue that the Emergency Department is actually the ideal setting to challenge these allergies. The “Oral Challenge”: Learn the practical steps for performing a trial dose in the department. Safety First: Why your environment and expertise make you uniquely qualified to handle the “what-ifs” better than anyone else. Key Takeaways Question the Label: The vast majority of reported penicillin allergies are inaccurate due to patients outgrowing the allergy or misinterpreting common side effects as allergic reactions. History is Everything: Dig deeper than just “rash.” Ask about the timing relative to the dose, specific appearance (hives vs. flat rash), and what treatment was required (epinephrine vs. antihistamines). Use PEN-FAST: Utilize this tool to objectify the risk. Document Tolerance: Even if you don’t fully delete the allergy label, if you successfully treat the patient with another beta-lactam (like ceftriaxone), document that tolerance clearly to aid future clinicians. Cephalosporins are likely safe: Later-generation cephalosporins generally have very low cross-reactivity and are usually safe options even in truly allergic patients How do you handle documented penicillin allergies? Do you use the PEN-FAST tool? Share your experience with us on social media @empulsepodcast or at ucdavisem.com Hosts: Dr. Julia Magaña, Professor of Pediatric Emergency Medicine at UC Davis Dr. Sarah Medeiros, Professor of Emergency Medicine at UC Davis Guests: Haley Burhans, PharmD, Emergency Medicine Clinical Pharmacist at UC Davis Resources: PEN-FAST Score on MDCalc Penicillin Allergy Evaluation Should Be Performed Proactively in Patients with a Penicillin Allergy Label – A Position Statement of the American Academy of Allergy, Asthma & Immunology Staicu ML, Vyles D, Shenoy ES, Stone CA, Banks T, Alvarez KS, Blumenthal KG. Penicillin Allergy Delabeling: A Multidisciplinary Opportunity. J Allergy Clin Immunol Pract. 2020 Oct;8(9):2858-2868.e16. doi: 10.1016/j.jaip.2020.04.059. PMID: 33039010; PMCID: PMC8019188. Yang C, Graham JK, Vyles D, Leonard J, Agbim C, Mistry RD. Parental perspective on penicillin allergy delabeling in a pediatric emergency department. Ann Allergy Asthma Immunol. 2023 Jul;131(1):82-88. doi: 10.1016/j.anai.2023.03.023. Epub 2023 Mar 27. PMID: 36990206. *** Thank you to the UC Davis Department of Emergency Medicine for supporting this podcast and to Orlando Magaña at OM Productions for audio production services.
Dr. Nancy O'Hara, pediatrician and leading expert in PANS and PANDAS, joins me to unpack why some children experience sudden, dramatic changes in behavior, anxiety, OCD, tics, sleep, or emotional regulation following illness. For many families, these symptoms appear almost overnight and are often misdiagnosed as "just anxiety," behavioral issues, or psychiatric disorders, leaving parents confused, dismissed, and unsure how to help their child. Together we explore: - What PANS and PANDAS are, and how infections like strep, viruses, or tick-borne illness can trigger sudden neuropsychiatric symptoms in children. - What to assess to help you determine if your child has a generalized anxiety disorder or if it may be PANS/PANDAS that is the root cause of their symptoms. - Why PANS/PANDAS is often missed or misunderstood in both medical and mental health settings. - The three-pronged approach to treatment: Addressing the trigger, the immune system, and the child's emotional and behavioral symptoms. - How therapy, both for parents and children, can support recovery, even when symptoms have a medical origin. - Understanding that there is real hope for healing and that it's never too late to identify and address PANS or PANDAS. This episode is designed to help parents and clinicians feel more informed, less alone, and more confident in recognizing when a child's behavior may be signaling something deeper. PANS and PANDAS are real, treatable conditions that deserve compassionate, comprehensive care. LEARN MORE ABOUT MY GUEST:
In this episode, we continue our series on neonatal opioid withdrawal syndrome (NOWS) with a discussion of substance exposure in the perinatal period and the practical considerations surrounding testing and discharge planning. Our host, Paul Wirkus, MD, FAAP and guest Camille Fung, MD review the fundamentals of prenatal substance exposure and the rationale for testing, including what different methods - such as urine, meconium, and umbilical cord testing - can and cannot tell us. The conversation explores the limitations of testing and how results should be interpreted in the clinical and social context of each family.We also discuss discharge planning, including referrals to primary care pediatricians and child welfare agencies when appropriate, and what clinicians and families can expect regarding developmental follow-up. Throughout the episode, Dr. Fung emphasizes the importance of a nonjudgmental, supportive approach that fosters trust and promotes the best outcomes for infants and their caregivers.Have a question? Email questions@vcurb.com. They will be answered in week four.For more information about available credit, visit vCurb.com.ACCME Accreditation StatementThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Colorado Medical Society through the joint providership of Kansas Chapter, American Academy of Pediatrics and Utah Chapter, AAP. Kansas Chapter, American Academy of Pediatrics is accredited by the Colorado Medical Society to provide continuing medical education for physicians. AMA Credit Designation StatementKansas Chapter, American Academy of Pediatrics designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
In this episode, we continue our series on neonatal opioid withdrawal syndrome (NOWS) with a discussion of substance exposure in the perinatal period and the practical considerations surrounding testing and discharge planning. Our host, Paul Wirkus, MD, FAAP and guest Camille Fung, MD review the fundamentals of prenatal substance exposure and the rationale for testing, including what different methods - such as urine, meconium, and umbilical cord testing - can and cannot tell us. The conversation explores the limitations of testing and how results should be interpreted in the clinical and social context of each family.We also discuss discharge planning, including referrals to primary care pediatricians and child welfare agencies when appropriate, and what clinicians and families can expect regarding developmental follow-up. Throughout the episode, Dr. Fung emphasizes the importance of a nonjudgmental, supportive approach that fosters trust and promotes the best outcomes for infants and their caregivers.Have a question? Email questions@vcurb.com. They will be answered in week four.For more information about available credit, visit vCurb.com.ACCME Accreditation StatementThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Colorado Medical Society through the joint providership of Kansas Chapter, American Academy of Pediatrics and Utah Chapter, AAP. Kansas Chapter, American Academy of Pediatrics is accredited by the Colorado Medical Society to provide continuing medical education for physicians. AMA Credit Designation StatementKansas Chapter, American Academy of Pediatrics designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Description: Nail psoriasis is tough to treat. Hear Rebecca, a patient who lives with nail psoriasis, and dermatologist Dr. Paul Yamauchi discuss the diagnosis, care, and treatment for this high-impact site. Join host Roy Pankey as he addresses the complexities of nail psoriasis from diagnosis to coping and the latest research and treatments with leading dermatologist, Dr. Paul Yamauchi from the Dermatology Institute and Skin Care Center and Clinical Science Institute, and Rebecca, a patient advocate with the National Psoriasis Foundation who lives with nail psoriasis. Listen as they discuss the challenges associated with living with nail psoriasis, and what can be done to help manage the disease from self-care to treatment choices – including the latest research developments. While nail psoriasis can be challenging to diagnose and treat, there are many actions that can be taken to help minimize the impact of this disease. Timestamps: (0:00) Intro to Psoriasis Uncovered & guest welcome Rebecca and dermatologist Dr. Paul Yamauchi. (0:58) Signs or changes to nails that indicate nail psoriasis is present. (2:07) Elements and challenges to diagnosing nail psoriasis. (4:41) What is a nail biopsy and how is it done. (5:25) How nail psoriasis relates to psoriatic arthritis. (6:19) What flares my nail psoriasis. (6:57) There are many treatment choices used to treat nail psoriasis based on convenience, impact of disease, preference, and when to expect improvement. (10:13) A personal perspective on medications used to treat nail psoriasis. (10:42) Research results of the latest medications used to treat nail psoriasis. (13:03) Upcoming oral agents that could be effective in treating nail psoriasis. (15:14) Self care tips, use of nail polish and artificial nails. (19:21) Nail psoriasis is challenging to treat. Be patient with yourself and your dermatologist. Key Takeaways: · Nail psoriasis presents many challenges from living and coping with the disease to diagnosis and treatment. · Medication choices for nail psoriasis are based on convenience, impact of disease, and preference for use of topicals, phototherapy, oral agents, and/or biologics. · Since nail psoriasis takes time to see improvement, it is important to be patient with yourself and your dermatologist. Guest Bios: Dermatologist Dr. Paul Yamauchi is President and Medical Director of the Dermatology Institute and Skin Care Center and Clinical Science Institute in Santa Monia, CA. Dr. Yamauchi is a leading expert in the field of psoriasis and has extensive experience treating different types of psoriasis using the latest treatments from topicals to biologics. He is also a Clinical Professor in the Division of Dermatology with David Geffen School of Medicine at UCLA. Dr. Yamauchi has conducted over 200 clinical research trials as principal investigator and is widely regarded as an outstanding clinical research investigator exploring innovative therapies, serving on advisory panels designing protocols that led to FDA approval of various medications. Dr. Yamauchi is a past member of the Medical Board of the National Psoriasis Foundation and is a fellow of the American Academy of Dermatology, and the American Society of Dermatology Surgery. Rebecca Cohen, is a patient advocate, who was diagnosed with plaque, scalp, and nail psoriasis at age 6 after being adopted by a dermatology physician's assistant who quickly found the best treatment path for her. Prior to that time she was told she had eczema. "My skin actually was really bad as a child. Horrible. Hands, feet, elbows, everything." Eventually after experiencing joint pain and fatigue, she was also diagnosed with psoriatic arthritis around age 20 at which time she started on her first biologic. "I struggled a lot with nail pitting and thickness as a kid and have recently been going through another episode." Resources: -Still have questions? Contact the Patient Navigation Center . -Nail Psoriasis or Nail Fungus? Advance Online June 2025. -What Your Nails Can Tell Your Doctor About PsA Advance Online March 2020
This week on The Hamilton Review Podcast, we're pleased to welcome pediatrician Dr. Cori Cross. In this episode, Dr. Cross explores the impact of social media on children and offers practical guidance for parents navigating today's complex digital landscape. Drawing from her Peds in Review article, "The Complicated Reality of Social Media," Dr. Cross joins Dr. Bob for a thoughtful discussion that takes a deeper look at the challenges and opportunities social media presents for families. We hope you enjoy this important and timely conversation. Cori Cross is a board-certified pediatrician and has been serving the LA community since her residency at Children's Hospital Los Angeles (CHLA) in 2004. Dr. Cross graduated cum laude from Barnard College with a BA in philosophy. She attended The University of Medicine and Dentistry of New Jersey, where she obtained her M.D. and was elected to the AOA honor society. Dr. Cross works as an advocate and public educator speaking nationally and locally to children and adults on a variety of topics. She is an American Academy of Pediatrics (AAP) Spokesperson and uses this platform to advocate for children and educate the public on pediatric and public health issues. In addition to interviews on behalf of the AAP, she is a repeat medical expert on CNN's Headline News and Los Angeles' CBS news. After years on the interviewee side of things, Dr. Cross can now be heard hosting peer-to-peer medical podcasts for RadioMD. In 2010 with the advent of the iPad, it was evident that screens would have a profoundly different effect on this next generation. Dr. Cross joined the AAP's Council on Communications and Media and served two terms on the Executive Committee. She was a lead author on the AAP's "Media Use in School-Aged Children and Adolescents" as well as the accompanying technical report "Children and Adolescents and Digital Media." She has continued working and educating in this space, giving talks locally and nationally to parents, student, educators and pediatricians. She partnered with Common Sense Media locally to give panel discussions and nationally to develop resources for pediatricians to address these issues in their offices. In 2017, she won an Outstanding Achievement in Innovation Award from the AAP for her work in creating the Family Media Use Plan Toolkit on HealthyChildren.org. She has continued to work with the AAP to update these resources and policies. She authored The Complicated Reality of Social Media, published in August of 2025 in Peds in Review and co-authored Digital Ecosystems, Children and Adolescents Policy Statement and Technical Report published in Pediatrics in January of 2026. How to contact Dr. Cori Cross: Dr. Cori Cross Website How to contact Dr. Bob: Dr. Bob on YouTube: https://www.youtube.com/channel/UChztMVtPCLJkiXvv7H5tpDQ Dr. Bob on Instagram: https://www.instagram.com/drroberthamilton/ Dr. Bob on Facebook: https://www.facebook.com/bob.hamilton.1656 Dr. Bob's Seven Secrets Of The Newborn website: https://7secretsofthenewborn.com/ Dr. Bob's website: https://roberthamiltonmd.com/ Pacific Ocean Pediatrics: http://www.pacificoceanpediatrics.com/
PeDRA Fellow Hannah Chang hosts a roundtable discussion with Dr. Jillian Rork and Dr. Deepti Gupta about a recent publication titled: Prevalence and Demographics of Psoriasis in the Down Syndrome Population: A Cross-Sectional Analysis Using the Epic Cosmos Dataset. This article was published in the Journal of the American Academy of Dermatology in September 2025.Tell us about you by taking this 1-question survey!
The American Society of Plastic Surgeons has released an updated statement recommending against gender surgeries for anyone under the age of 18. While the American Medical Association has issued a similar stance, other organizations—including the American Academy of Pediatrics—argue that healthcare decisions should remain between families and doctors, and that surgical options should stay on the table for minors. Earlier this week, plastic surgeon and star of Netflix's Skin Decision: Before and After, Dr. Sheila Nazarian, joined FOX News Rundown host Dave Anthony to explain why many in her field believe minors should not "go under the knife" for transition procedures. Dr. Nazarian raised alarms over the lack of long-term data regarding the effectiveness of these treatments, emphasizing her belief that evidence-based medicine must be the sole guide for treating gender dysphoria in children. She also discussed the professional risks of speaking out, noting that many in the medical community fear political backlash for questioning current standards of care. We often have to cut our interviews short during the week, but we thought you might like to hear this conversation in its entirety. Today on a Fox News Rundown Extra, we share our full interview with plastic surgeon Dr. Sheila Nazarian. Learn more about your ad choices. Visit podcastchoices.com/adchoices
The American Society of Plastic Surgeons has released an updated statement recommending against gender surgeries for anyone under the age of 18. While the American Medical Association has issued a similar stance, other organizations—including the American Academy of Pediatrics—argue that healthcare decisions should remain between families and doctors, and that surgical options should stay on the table for minors. Earlier this week, plastic surgeon and star of Netflix's Skin Decision: Before and After, Dr. Sheila Nazarian, joined FOX News Rundown host Dave Anthony to explain why many in her field believe minors should not "go under the knife" for transition procedures. Dr. Nazarian raised alarms over the lack of long-term data regarding the effectiveness of these treatments, emphasizing her belief that evidence-based medicine must be the sole guide for treating gender dysphoria in children. She also discussed the professional risks of speaking out, noting that many in the medical community fear political backlash for questioning current standards of care. We often have to cut our interviews short during the week, but we thought you might like to hear this conversation in its entirety. Today on a Fox News Rundown Extra, we share our full interview with plastic surgeon Dr. Sheila Nazarian. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Depending on one's outlook and relationship status (and a willingness to spend lavishly on romantic gestures), Valentine's Day is an annual ritual to be loved or loathed. But is it living up to its unstated end goal – i.e., romance blossoming into love and commitment, which in turn leads to parenthood? Valerie Ramey, an economist and the Hoover Institution's Thomas Sowell Senior Fellow, looks at the economic engine that is Valentines Day (literally “a day of wine and roses”), the various social factors that've contributed to America's declining birth rate, plus why it is that modern-day parents engage in what she calls the "rug rat race” – mothers and fathers raising children in a more hands-on manner so as to assure their progeny are admitted to top-flight universities. Recorded on February 12, 2026. ABOUT THE SPEAKERS Valerie Ramey is the Thomas Sowell Senior Fellow at the Hoover Institution. She is also a research associate of the National Bureau of Economic Research, a Research Fellow of the Centre for Economic Policy and Research, a member of the American Academy of Arts and Sciences, and a Fellow of the Econometric Society. Ramey has published numerous scholarly and policy-relevant articles on macroeconomic topics such as the sources of business cycles, the effects of monetary and fiscal policy, the effects oil price shocks, and the impact of volatility on growth. She has also written numerous articles on trends in wage inequality and trends in time use, such as the increase in time investments in children by educated parents. Her work has been featured in major media, such as the Wall Street Journal and the New York Times. Bill Whalen, the Virginia Hobbs Carpenter Distinguished Policy Fellow in Journalism and a Hoover Institution research fellow since 1999, writes and comments on campaigns, elections and governance with an emphasis on California and America's political landscapes. Whalen writes on politics and current events for various national publications, as well as Hoover's California On Your Mind web channel. Whalen hosts Hoover's Matters of Policy & Politics podcast and serves as the moderator of Hoover's GoodFellows broadcast exploring history, economics, and geopolitical dynamics. RELATED SOURCES The Rug Rat Race by Garey Ramey & Valerie A. Ramey ABOUT THE SERIES Matters of Policy & Politics, a podcast from the Hoover Institution, examines the direction of federal, state, and local leadership and elections, with an occasional examination of national security and geopolitical concerns, all featuring insightful analysis provided by Hoover Institution scholars and guests. To join our newsletter and be the first to tune into the next episode, visit Matters of Policy & Politics.
Send a textDR. WILLIAM BRUNO is a board-certified plastic surgeon based in Beverly Hills, California, Where he's practiced aesthetic surgery since 2004. As a member of the American Society of Plastic Surgeons, the American Society for Aesthetic Plastic Surgery, and the American Academy of Anti-Aging Medicine, Dr. Bruno has performed over 6,000 procedures specializing in breast and body contouring.www.williambrunomd.comInstagram @williambrunomdUse code FA FOR 40% OFF Athletic greens is a non-negotiable part of my daily routine. With 75 absorbable vitamins and minerals in just one scoop a day, I have increased my energy, improved my immune function and so much more. To get your own AG at 20% off go to www.athleticgreens.com/functionallyautoimmune Order now for a free vitamin D3/K2 supplement and 5 free travel packs!Support the show
Screens are ubiquitous in today's world, and concerns about how they affect kids are mounting. Last month, Australia banned social media use for kids under 16, with some European countries poised to follow. But what's the science on how neverending YouTube videos or TikToks affect kids' brains and bodies? Joining Host Flora Lichtman to discuss are neuroscientist John Foxe and behavioral developmental pediatrician Jenny Radesky.Guests:Dr. John Foxe is Director of The Del Monte Institute for Neuroscience at the University of Rochester in New York.Dr. Jenny Radesky is a developmental behavioral pediatrician at the University of Michigan in Ann Arbor. She's also co-Medical Director of the American Academy of Pediatrics Center of Excellence on Social Media and Youth Mental Health.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
A newly proposed rule from the U.S. Department of Education could significantly restrict access to federal student loans for Physician Associate (PA) students — threatening the future PA pipeline and patient access to care.In this rapid response episode, Tracy breaks down:What the Department of Education's proposed rule actually saysHow changes to federal student loan eligibility could limit PA education accessWhy fewer PA students = fewer clinicians = longer wait times + more burnoutWhat the American Academy of Physician Associates (AAPA) is doingHow YOU can take action in less than 10 minutesThis is advocacy in action. And it matters.
In this throwback episode honoring National Women Physicians Day, host Shikha Jain, MD, with Physicianary's Hansa Bhargava, MD, and Mend the Gap's Dagny Zhu, MD, discuss the evolution of empowering yourself and others and advocacy with a panel of guests. · Intro 0:32 · What does it mean to empower women in medicine, and what are the ways that we can really empower others to achieve the things that they may not see for themselves? 1:37 · What are some ways in which you have empowered or hope to empower women in medicine? Are there tips or skills that have worked well? 4:41 · How have you been empowered by others, or have helped others find their voices? 7:37 · Do you agree that the conversation is changing toward a cultural shift in empowerment for women in health care? 12:23 · What are some challenges facing advocacy and empowerment? […] What do you do when your advocacy work is not being received or it is a struggle to speak up for someone? 17:10 · Emphasizing the importance of communication in advocacy work. 22:23 · Intro to Physicianary's part 3 on physician burnout and work-life balance. 22:51 · Thanks for listening 23:31 Be sure to listen to Part 1 and Part 3 of Healio's Women In Medicine roundtable discussion, streaming everywhere now! Vineet Arora, MD, MAPP (NAM), is a Herbert T. Abelson professor of medicine, vice dean of education in the biological sciences division and dean for medical education at the University of Chicago Pritzker School of Medicine. She is also an elected member of the National Academy of Medicine. She is a founding member of the 501c3 Women of Impact and advisor to the Women in Medicine Summit. Jennifer Bepple, MD, MMCi, is a double board-certified physician in urology and informatics. She is a member of the American Telemedicine Association, American Urologic Association and American Medical Informatics Association and holds a certification from the American Board of Telehealth and the American Board of AI in Medicine. Hansa Bhargava, MD, is Healio's chief clinical strategy and innovation officer. Listen to her Healio podcast, Physicianary. Shikha Jain, MD, FACP, is a board-certified hematology and oncology physician. She is a tenured associate professor of medicine in the division of hematology and oncology, the director of communication strategies in medicine and the associate director of oncology communication & digital innovation at the University of Illinois Cancer Center in Chicago. Mara Schenker, MD, FACS, FAOA, is an orthopedic trauma surgeon at Grady Memorial Hospital. She is double board certified in orthopedic surgery and clinical informatics. She serves as the chief of orthopedics and associate chief medical information officer. She is an associate professor of orthopedics at Emory University School of Medicine. She serves on multiple boards for medical and digital technology advisory and sits on major national committees for the American Academy of Orthopaedic Surgeons, AAMC, American College of Surgeons and the Orthopaedic Trauma Association. Dagny Zhu, MD, is a cornea, cataract and refractive surgeon and medical director and partner at NVISION Eye Centers in Rowland Heights, CA. She can be reached on X @DZEyeMD. Listen to her on Healio's Mend The Gap: Equity In Medicine podcast. We'd love to hear from you! Send your comments/questions to Dr. Jain at oncologyoverdrive@healio.com. Follow Healio on X and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/. Follow Dr. Jain on X: @ShikhaJainMD. Disclosures: The hosts and guests report no relevant financial disclosures.
What if lasting energy and better health didn't require complicated routines or constant stress? In this episode, Dr. Debbie Ozment, DDS, shares her refreshingly simple approach to enhancing vitality, preventing disease, and creating sustainable wellness habits that truly work. As the host of the Vitality Made Simple podcast, Dr. Ozment focuses on early detection, prevention, and practical strategies that help people feel their best at every stage of life. With decades of experience in dentistry and integrative health, she highlights how oral health, inflammation, toxins, and emotional stress can quietly drain energy and impact long-term wellbeing — and what you can do about it. In this conversation, we explore: · How small, consistent lifestyle changes can extend your vitality span · The connection between oral health, inflammation, and chronic disease prevention · Simple, stress-free ways to support mental, emotional, and physical wellness Dr. Ozment has been in private dental practice since 1985 and is a graduate of the University of Oklahoma College of Dentistry. She later earned a Master's degree in Metabolic and Nutritional Medicine from the University of South Florida Morsani College of Medicine and is a Diplomate of the American Academy of Anti-Aging Medicine. Trained at the Mayo Clinic and certified as a National Board-Certified Health and Wellness Coach, she brings a truly integrative perspective to modern health. Follow Dr. Ozment on Instagram @drdebbieozment to stay up to date with her latest insights and resources. Episode also available on Apple Podcasts: https://apple.co/38oMlMr Keep up with Debbie Ozment socials here: Facebook: https://www.facebook.com/drdebbieozment/ Youtube: https://www.youtube.com/@drdebbieozment
Send a textSchedule an Rx AssessmentRapid growth is exciting but without the right metrics, culture, and plan, it can quietly put your pharmacy at risk.In this episode, Scotty Sykes, CPA, CFP®, Bonnie Bond, CPA, MBA, and Austin Murray sit down with Jim Hrncir, R. Ph. FACP, Owner of Las Colinas Compounding Pharmacy and Wellness Center veteran compounding pharmacist and owner, to unpack what it really takes to run a sustainable compounding pharmacy through industry cycles, GLP-1 volatility, and ownership transitions.We cover:The KPIs Jim actually tracks to manage a complex compounding operationWhy cash position may be the most overlooked metric in pharmacyHow GLP-1s changed the business—and why diversification still mattersInternal succession vs. private equity: the real tradeoffsAnd more!More About Our Guest:Jim Hrncir RPh and wife Jan founded Las Colinas Pharmacy, Compounding & Wellness in 1984. Recognized as one of the pioneers of modern pharmaceutical compounding, Jim's 1986 creation of Estradiol Transdermal Gel was the first of its kind in the United States. He is responsible for the formulation of many Bio-Identical Hormone, Dermatological, Nutritional, and Anti-Aging compounds in wide use throughout the United States. Jim was named the 2017 Compounding Pharmacist of the Year by Professional Compounding Centers of America (PCCA) and is a Fellow of the Alliance for Pharmacy Compounding (FAPC). NCPA's magazine America's Pharmacist featured Jim and Las Colinas Pharmacy as the cover story for December 2018.Jim has received extensive continuing education in the areas of Bio-Identical Hormones, Nutrition, Anti-Aging Medicine, Weight Management, Pain Management, Neurotransmitter Management, Natural and Functional Medicine including the use of botanical medicines, nutritional supplements, Detoxification and Purification, homeopathy and lab testing. He has lectured across the country on a variety of topics including Clinical Patient Consulting, BHRT Assessment and Case Management, Low Dose Naltrexone, Traumatic Brain Injury Treatment Protocols, and Ketamine for Treatment-Resistant Depression and PTSD.Jim is a member of Professional Compounding Centers of America (PCCA), American Academy of Anti-Aging Medicine, Age Management Medical Group, Texas Pharmaceutical Association, Alliance for Pharmacy Compounding, and the National Association of Community Pharmacists.Stay connected with Jim and Las Colinas Pharmacy: Jim's LinkedInLas Colinas Pharmacy WebsiteLas Colinas Pharmacy FacebookLas Colinas Pharmacy TikTokLas Colinas Pharmacy InstagramLas Colinas Pharmacy LinkedInStay connected with us: FacebookYouTube LinkedInInstagram More resources on this topic: Podcast - Driving Independent Pharmacy Profitability in 2026Podcast – The Startup Compounding Pharmacy Playbook
THIS IS A PREVIEW. FOR THE FULL EPISODE, GO TO Patreon.com/worstofall The lads grab their heart-boxes and make for the creepy woods as they cover Walt Disney's 1937 landmark animated film: Snow White and the Seven Dwarfs. Topics include the origins of Walter Elias Disney, the make-it-up-as-you-go-along production, and the enduring legacy of the film that built the Disney empire. Media Referenced in this Episode: Snow White and the Seven Dwarfs. Dir. Walt Disney. 1937. “Before Snow White” by J.B. Kaufman. Film History, Jun., 1993, Vol. 5, No. 2, Animation (Jun., 1993), pp. 158-175 “The Disney Way of Death” by Gary Laderman. Journal of the American Academy of Religion, Mar., 2000, Vol. 68, No. 1 (Mar., 2000), pp. 27-46. Oxford University Press. “The Great Animation Strike” by Kristin Hunt. JSTOR Daily. January 2nd, 2020. Walt Disney: An American Original by Bob Thomas. Simon & Schuster. 1976. Walt Disney: The Triumph of the American Imagination by Neal Gabler. Alfred A. Knopf. 2006. “‘With a smile and a song …': Walt Disney and the Birth of the American Fairy Tale” by Tracey Mollet. Marvels & Tales, Vol. 27, No. 1 (2013), pp. 109-124. Wayne State University Press TWOAPW theme by Brendan Dalton: Patreon // brendan-dalton.com // brendandalton.bandcamp.com Interstitial: “Hermann Huntsmann's Heart-Box Hut” // Written by A.J. Ditty // feat. A.J. Ditty “Hermann Huntsmann/The Animals” and Eleanor Philips “Snow White”
Many serious medical illnesses are associated with some degree of serum electrolyte abnormality, renal impairment, or both. The neurologist must determine if the patient's neurologic symptoms are related to the renal and electrolyte disturbances or whether a concurrent primary neurologic process is at play. In this episode, Casey Albin, MD, speaks with Eelco F. M. Wijdicks, MD, PhD, FAAN, FACP, FNCS, author of the article "Neurologic Manifestations of Renal and Electrolyte Disorders" in the Continuum® February 2026 Neurology of Systemic Disease issue. Dr. Albin is a Continuum® Audio interviewer, associate editor of media engagement, and an assistant professor of neurology and neurosurgery at Emory University School of Medicine in Atlanta, Georgia. Dr. Wijdicks is a professor of neurology and attending neurointensivist for the Neurosciences Intensive Care Unit at Mayo Clinic in Rochester, Minnesota. Additional Resources Read the article: Neurologic Manifestations of Renal and Electrolyte Disorders Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @caseyalbin Guest: @EWijdicks Full episode transcript available here
In this episode, we continue our discussion of neonatal opioid withdrawal syndrome (NOWS), focusing on clinical features, treatment, and care after discharge. Our host, Paul Wirkus, MD, FAAP and guest Camille Fung, MD review the signs and symptoms clinicians use to recognize and assess withdrawal, along with current approaches to medication management and supportive care in the hospital setting. The conversation also addresses discharge planning, including criteria for safe transition home and coordination with caregivers. Finally, we explore the important role of the primary care pediatrician in follow-up—monitoring growth and development, supporting families, and coordinating ongoing services to promote the best possible outcomes for these infants. Have a question? Email questions@vcurb.com. They will be answered in week four.For more information about available credit, visit vCurb.com.ACCME Accreditation StatementThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Colorado Medical Society through the joint providership of Kansas Chapter, American Academy of Pediatrics and Utah Chapter, AAP. Kansas Chapter, American Academy of Pediatrics is accredited by the Colorado Medical Society to provide continuing medical education for physicians. AMA Credit Designation StatementKansas Chapter, American Academy of Pediatrics designates this live activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Hosted by Dr. Lauren Kim, this episode explores the most downloaded Radiology article of 2025 with guests Dr. Carolyn Wang, Dr. Allison Ramsey, and Dr. David Lang, focusing on updated consensus guidance for managing hypersensitivity reactions to iodinated contrast media. The discussion highlights major changes in clinical practice, including more selective use of corticosteroid premedication and switching contrast agents when feasible to reduce the risk of recurrent reactions and standardize patient care. Management and Prevention of Hypersensitivity Reactions to Radiocontrast Media: A Consensus Statement from the American College of Radiology and the American Academy of Allergy, Asthma & Immunology. Wang et al. Radiology 2025; 315(2):e240100.
In his weekly clinical update during Ground hog week, Dr. Griffin and Vincent Racaniello are back to discuss the measles outbreak in South Carolina, American Academy of Pediatrics vaccine recommendations and shingles vaccine and the reduction of dementia, then deep dives into recent statistics RSV, influenza and SARS-CoV-2 infections, the Wastewater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to access and pay for Paxlovid, estimated effectiveness of this year's COVID-19 vaccine, long COVID treatment center, where to go for answers to your long COVID questions, long COVID in children, the potential benefits of metformin to reduce disease severity following SARS-CoV-2 infection in obese and overweight patients and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Grading the groundhogs (National Oceanic and Atmospheric Administration) Sand Mountain Sam predicts an early spring (News19) All About the AAP Recommended Immunization Schedule (healthychildren.org) Recommended Childhood and Adolescent Immunization Schedule: United States, 2026: Policy Statement (American Academy of Pediatrics: Pediatrics) Herpes zoster vaccination and incident dementia in Canada: an analysis of natural experiments (LANCET: Neurology) Detection of avian flu antibodies in Dutch dairy cow: ECDC risk assessment remains unchanged (European Centre for Disease Prevention and Control) Wastewater for measles (WasterWater Scan) Measles cases and outbreaks (CDC Rubeola) Big outbreak, bright lights…Measles Dashboard(South Carolina Department of Public Health) Tracking Measles Cases in the U.S. (Johns Hopkins) Measles vaccine recommendations from NYP (jpg) Weekly measles and rubella monitoring (Government of Canada) Measles (WHO) Get the FACTS about measles (NY State Department of Health) Measles(CDC Measles (Rubeola)) Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC) Adverse events associated with childhood vaccines: evidence bearing on causality (NLM) Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America) Deaths following vaccination: what does the evidence show (Vaccine) Influenza: Waste water scan for 11 pathogens (WastewaterSCan) US respiratory virus activity (CDC Respiratory Illnesses) Respiratory virus activity levels (CDC Respiratory Illnesses) Weekly surveillance report: clift notes (CDC FluView) OPTION 2: XOFLUZA $50 Cash Pay Option(xofluza) RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health) USrespiratory virus activity (CDC Respiratory Illnesses) RSV-Network (CDC Respiratory Syncytial virus Infection) Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP) Waste water scan for 11 pathogens (WastewaterSCan) COVID-19 deaths (CDC) Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses) COVID-19 national and regional trends (CDC) COVID-19 variant tracker (CDC) SARS-CoV-2 genomes galore (Nextstrain) Estimated Effectiveness of 2024-2025 COVID-19 Vaccination Against Severe COVID-19 (JAMA) Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD) Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC) NIH COVID-19 treatment guidelines (NIH) Drug interaction checker (University of Liverpool) Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro) Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society) Molnupiravir safety and efficacy (JMV) Convalescent plasma recommendation for immunocompromised (ID Society) What to do when sick with a respiratory virus (CDC) Managing healthcare staffing shortages (CDC) Anticoagulationguidelines (hematology.org) Daniel Griffin's evidence based medical practices for long COVID (OFID) Long COVID hotline (Columbia : Columbia University Irving Medical Center) The answers: Long COVID Long COVID associated with SARS-CoV-2 reinfection among children and adolescents in the omicron era (RECOVER-EHR): a retrospective cohort study (LANCET: Infectious Diseases) Long COVID is here to stay—even in children (LANCET: Infectious Diseases) Early administration of neutralising monoclonal antibodies and post-acute sequelae of COVID-19 (International Journal of Infectious Diseases) Preventing Long COVID With Metformin (CID) Metformin may reduce risk of long COVID by 64% in overweight or obese adults (CIDRAP) Effect of Metformin on the Risk of Post-coronavirus Disease 2019 Condition Among Individuals With Overweight or Obese (CID) Preventing Long COVID With Metformin (CID) New review highlights growing evidence that diabetes drug metformin can prevent long COVID (CIDRAP) Reaching out to US house representative Letters read on TWiV 1294 Dr. Griffin's COVID treatment summary (pdf) Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv Content in this podcast should not be construed as medical advice.