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Results from a large study in Ethiopia showed that P. falciparum malaria parasites have mutated and have the worrisome ability to avoid being detected by the widely utilized RDTs. Transcript Controlling malaria requires an effective ‘test and treat' strategy. Traditionally, the most utilized test in Africa is the rapid diagnostic test (RDT), which detects histidine-rich protein 2, a protein made by P. falciparum malaria parasites. Although histidine-rich protein is abundant in human blood during malaria infection and an excellent target for testing - it's been reported since 2010 that mutations in the parasite have resulted in the deletion of the gene encoding this protein, enabling those parasites to avoid detection by RDTs.In a large study of nearly 13,000 participants conducted in Ethiopia results from RDTs were cross-referenced with those from more reliable methods of diagnosis. Researchers found that RDTs would miss an estimated 9.7% of cases owing to the deletion of this protein, significantly higher than the WHO's 5% threshold for test regime change. Source Plasmodium falciparum is evolving to escape malaria rapid diagnostic tests in Ethiopia About The Podcast The Johns Hopkins Malaria Minute podcast is produced by the Johns Hopkins Malaria Research Institute to highlight impactful malaria research and to share it with the global community.
Transcript -- Complications of trying to control money.
Transcript -- The tail rotor keeps the helicopter from rotating. The cyclic stick is responsible for speed, direction and altitude control.
Transcript -- The tail rotor keeps the helicopter from rotating. The cyclic stick is responsible for speed, direction and altitude control.
Introducing Health Sciences: The Pain Clinic - for iPod/iPhone
Transcript -- A doctor at the Royal Free Hospital's Pain Clinic performs a procedure and explains how medication can help alleviate pain.
Introducing Health Sciences: The Pain Clinic - for iPad/Mac/PC
Transcript -- A doctor at the Royal Free Hospital's Pain Clinic performs a procedure and explains how medication can help alleviate pain.
Transcript -- Controlling fingers and wrist to draw shapes and letters.
Transcript -- Controlling your fingers and wrists when drawing ovals.
Transcript -- Controlling fingers and wrist to draw shapes and letters.
Transcript -- Controlling your fingers and wrists when drawing ovals.