Abdominal Aortic Aneurysm Summit

Susan Lindquist, Professor of Biology at the Massachusetts Institute of Technology (MIT), and Member of the Whitehead Institute for Biomedical Research, delivers the 12th Annual Dorfman Memorial Lecture. (December 15, 2009)

Christine Scotti discusses, from the manufacturer's point of view, the use of fluid dynamics in creating endovascular grafts in corroboration with other specialists in the field to maximize device stability. (September 5, 2008)

Charles A. Taylor and Ronald L. Dalman give thanks to all presenters and people involved in the summit and call for future collaboration to better each individual's research results. (September 5, 2008)

Simona Zannetti, discusses device design from the manufacturer's point of view including the bureaucratic hurdles and testing procedures they face in finding safe and efficient measures to cure AAA disease. (September 5, 2008)

Christopher K. Zarins discusses the history of the development of endovascular reparation devices, the issue of migration with endograft devices. (September 5, 2008)

Ronald L. Dalman compares the current safety and cost effectiveness of open repair versus endovascular repair of abdominal aortic aneurysms. (September 5, 2008)

David Vorp discusses methods of predicting AAA rupture non-invasively, that is patient specific rather than based solely upon aneurysm diameter. (September 5, 2008)

Jonathan Gillard, discusses morphology and risk, cellular function in drug studies and contrast agents, and the importance of biomechanical processes in studies of AAA using MRI technology. (September 5, 2008)

Natzi Sakalihasan, MD, PhD, discusses his clinical studies of 18-FTG uptake by the AAA wall through PET imaging, and hypothesizes that patients with aneurysms of 55 mm diameter or larger could benefit from PET scanning. (September 5, 2008)

Geoffrey Rubin, MD, discusses the pros and cons of different types of imaging systems available for monitoring AAA progress. (September 5, 2008)

Zahi Fayad, PhD, discusses the possibility of using imaging to monitor the effect of angiostatic and anti-inflammatory therapy after administering local drug delivery. (September 5, 2008)

B. Timothy Baxter, MD, discusses different studies on chemical treatments that have been shown to effect AAA behavior. (September 4, 2008)

Dianna Milewicz, MD, PhD, discusses the idea that AAA might be partially caused by a rare genetic mutations in addition to environmental conditions that enhance disease progression. (September 5, 2008)

Ronald L. Dalman, MD discussions the shortcomings of monitoring AAA progression through diameter growth rates, which makes treatment of AAA disease difficult. (September 4, 2008)

Jay Humphrey, PhD, discusses his study of intracranial saccular aneurysms and how his results have mechanical similarities to abdominal aortic aneurisms in areas like blood flow and wall stress. (September 4, 2008)

Charles A. Taylor, PhD, discusses his research at Stanford university on blood flow distribution and wall shear stress in the abdominal aorta to learn how the growth of AAA can be effected through exercise and rest conditions. (September 4, 2008)

Paul Norman, DS, FRACS, discusses several different types of biomarkers, both chemical and genetic, and the need for greater instances of replication and screening to find more conclusive evidence for therapeutic methods. (September 4, 2008)

Roberty Peattie, PhD, discusses his research of flow fields in physically replicated models of the human aorta to discover the velocity of flow which causes wall shear stresses. (September 4, 2008)

Neal Weintraub, MD, discusses his research on oxidative stress locally increased in Abdominal Aortic Aneurysm Disease and the possibility that Taurine might be a safe mode of therapy for humans. (September 4, 2008)

Gerhard Holzapfel, PhD, discusses the nonlinear behavior of an aorta under stress testing. (September 4, 2008)

Alan Daugherty, PhD, DSc, discusses the influence of Angiotensin in the induction of Abdominal Aortic Aneurism Disease in mice. (September 4, 2008)

Robert Thompson, MD discusses the growth and inhibition of growth in abdominal aortic aneurysms through the degradation of elastin in his mouse model. (September 4, 2008)

Frank Lederle, MD, evaluates the rupture rates of abdominal aneurysm based upon the diameter of the aneurysm, as well as the influence of various diseases and conditions on enlargement rates. (September 4, 2008)

Ronald L. Dalman, MD, offers a brief introduction to the long term objective and purpose of Stanford's Specialized Center of Clinically Oriented Research in Abdominal Aoritic Aneurysm (AAA) Disease. (September 4, 2008)