Podcasts about mice

This episode of GEN's Touching Base spotlights the unexpected relationship between breathing low oxygen and restoration of neuron function in a mouse model of Parkinson's disease. In addition, a single gene therapy injected at birth now offers lasting protection from HIV in infant rhesus macaques. Rounding out our episode, we discuss key factors shaping this year's A-List of Top 10 U.S. Biopharma Clusters and recap the regulatory conflict surrounding Sarepta Therapeutics' Duchenne muscular dystrophy (DMD) gene therapy, Elevidys®—including the departure of Vinay Prasad, MD, the FDA official behind the agency's brief get-tough approach.Join GEN editors Corinna Singleman, PhD, Alex Philippidis, Fay Lin, PhD, and Uduak Thomas for a discussion of the latest biotech and biopharma news. Listed below are links to the GEN stories referenced in this episode of Touching Base:GLP-1 Drug Semaglutide Linked to Reduced Muscle Strength in MiceGEN, August 6, 2025Out of Thin Air: Hypoxia Reverses Parkinson's Symptoms in MiceBy Fay Lin, PhD GEN, August 6, 2025Early Gene Therapy Provides Lasting HIV Protection in Newborn PrimatesGEN, July 30, 2025StockWatch: As Prasad Exits FDA, Analysts See Benefit for Sarepta, CGT StocksBy Alex Philippidis, GEN Edge, August 3, 2025Sarepta to Resume Shipping DMD Gene Therapy to Ambulant PatientsBy Alex Philippidis, GEN Edge, July 28, 2025Sarepta Under Scrutiny, AstraZeneca's Big Bet, and AI vs. IDRsBy Alex Philippidis, Uduak Thomas, Fay Lin, PhD, Corinna Singleman, PhD, GEN, July 25, 2025About Face: Sarepta to Pause Elevidys Shipments TemporarilyBy Alex Philippidis, GEN Edge, July 21, 2025Touching Base PodcastHosted by Corinna Singleman, PhDBehind the BreakthroughsHosted by Jonathan D. Grinstein, PhDThe State of Biotech Summit Registration Hosted on Acast. See acast.com/privacy for more information.

In this episode of Genetics in Your World, GSA Early Career Scientist Multimedia Subcommittee member Faye Romero interviews Dr. Gary Churchill of the Jackson Laboratory about longevity-associated loci in diversity outbred mice. Read Dr. Churchill's paper titled, “Analysis of lifespan across diversity outbred mouse studies identifies multiple longevity-associated loci,” published in the August 2025 issue of G3: Genes|Genomes|Genetics: https://doi.org/10.1093/genetics/iyaf081Music: Loopster Kevin MacLeod (incompetech.com). Licensed under Creative Commons: By Attribution 3.0 License, http://creativecommons.org/licenses/by/3.0/ Hosted on Acast. See acast.com/privacy for more information.

In this episode we chat all about our first time on Disney's newest island destination - Lookout Cay at Lighthouse Point! We share how we spent our day, what we think compared to Castaway Cay, and the give some of our tried and true cruise tips at the end! Follow us on social media @babesonboardpod

When culinary arts teacher Michelle Chung first reported mice in her classroom, she never imagined it would lead to a parasite infection, major surgery, and a battle against a school district determined to silence her at all costs. In this powerful follow-up episode, Michelle reveals shocking new developments in her fight for classroom safety and accountability.The situation has escalated dramatically since her first appearance. After paying her own money for a professional inspection that confirmed hazardous conditions, Michelle discovered the district had covered her classroom in bleach to hide evidence of mouse urine and droppings, creating a toxic environment that even hazmat-suited inspectors couldn't safely remain in. Rather than addressing the dangers, administrators emptied her classroom while she was on medical leave, removed her nameplate, and incredibly, threatened students with detention for mentioning her name.This isn't just about one classroom, it's a window into systemic failures that prioritize institutional reputation over health and safety. As Michelle fights not just for her career but for student wellbeing, her story raises urgent questions about accountability in our educational system and what happens when dedicated teachers stand alone against administrative corruption.If you missed Part 1 of the story, you can download and listen here! For KTVB7 News coverage on the case click here!Disclaimer: Always do your due diligence as a parent and/or faculty.Send us a textSupport the showFollow Wild Chaos on Social Media: Apple iTunes: https://podcasts.apple.com/us/podcast/the-wild-chaos-podcast/id1732761860Spotify: https://open.spotify.com/show/5KFGZ6uABb1sQlfkE2TIoc?si=8ff748aa4fc64331 ⁠⁠⁠Instagram: https://www.instagram.com/wildchaospodcastBam's Instagram: https://www.instagram.com/bambam0069Youtube: https://youtube.com/@wildchaospodTikTok: ⁠⁠⁠https://www.tiktok.com/@wildchaosshowMeta (Facebook): ⁠⁠⁠https://www.facebook.com/TheWildChaosPodcast

Clones, torture, dead mice... Jack's starting to get into science   Support the show and get more shows www.patreon.com/troofseeking 

The big laws debated by Parliament get a lot of attention, but others are so small as to be barely noticed. Go to this episode on rnz.co.nz for more details

En un contexto global cada vez más volátil e impredecible, que ha venido marcado en los últimos meses por la continua amenaza de los aranceles estadounidenses, por un muy elevado aumento de los precios o por las guerras próximas a la Unión Europea, el sector MICE busca adaptarse a esta situación. ¿De qué manera? Hablamos con Claudio Castro, director de MICE en Patterson Travel; Pascale Wegmann, directora de operaciones de City Travel; y Rudolf Rannegger, managing director de Ovation; sobre cómo abordar el contexto geopolítico actual en el sector. 

The guys talk about football, getting arrested, and learn about aura farming. They also power rank Nickelodeon shows.Follow the show: @passthegravypod, @AlexJMiddleton, @NotPatDionne, and @RobertBarbosa03

The guys talk about football, getting arrested, and learn about aura farming. They also power rank Nickelodeon shows.Follow the show: @passthegravypod, @AlexJMiddleton, @NotPatDionne, and @RobertBarbosa03

SummaryIn this conversation, Jennifer Darling and Warren Olson discuss the evolution of fire protection, the importance of continuing education, and the role of mentorship in the fire service. They explore Warren's extensive career, his involvement with the NFPA, and the challenges faced in fire safety regulations. The discussion highlights the significance of teaching and the impact of major fire incidents on current safety practices.takeawaysMICE aims to simplify continuing education for providers and administrators.Warren Olson has over 50 years of experience in fire protection.He emphasizes the importance of mentorship in the fire service.Generational changes have improved firefighter health and safety.Teaching has been a passion for Warren throughout his career.NFPA technical committees play a crucial role in developing fire safety codes.Challenges in fire safety regulations are influenced by special interest groups.Lessons from past fire incidents shape current safety practices.The pendulum of fire safety regulations swings with public perception.Warren's journey reflects the importance of continuous learning in fire protection.Sound Bites"I've been doing this a long time.""Teaching gives me the greatest joy.""The codes are being chipped away."Chapters00:00Introduction to MICE and TrackMyCE.io01:25Warren Olson's Journey in Fire Protection05:55Career Progression and Experiences in Fire Service11:52Generational Changes in Fire Service17:52The Importance of Teaching and Mentorship23:52Involvement with NFPA Technical Committees29:54Challenges in Fire Safety Regulations35:56Lessons from Major Fire Incidents41:33Reflections on Fire Safety and Future Directions

Sébastien Gauvrit was only ten when his family let him have his first tank of guppies. Within weeks, he was hooked.   “I actually had to understand genetics directly by mixing these different fish together to get the colour or fin shape I was interested in,” said the vascular biologist and genetic modelling pioneer. From his home in France, to post-doctoral work pioneering new models for vascular disease in Germany, to his current position as an assistant professor of Anatomy, Physiology and Pharmacology at the University of Saskatchewan's College of Medicine —  tropical fish tanks remain a constant in Gauvrit's life.   This year, two grants from the National Sciences and Engineering Research Council of Canada (NSERC) totalling $340,000 mean Dr. Gauvrit will expand the University of Saskatchewan's zebrafish aquariums — and refine his laboratory's modelling work and research on vascular development.   Zebrafish are transparent in their first hours and days, which allows scientists to watch them forming vascular cells in real time.   “Most genes that trigger vascular disease in humans are present in zebrafish,” Gauvrit said, noting they share 70 per cent of of their genes with humans.   Using both fish and rodent models, Gauvrit will do a deeper analysis of the transcription factor HHEX [Hematopoietically Expressed Homeobox], because of its cascading effect on the cells that eventually determine lymphatic health.   “If you understand how this gene regulates others, we can identify new genes involved in lymphatic disease, and understand a bit more the process behind all these events,” Gauvrit said.   He's also looking at VEGF-A [vascular endothelial growth factor], a gene implicated in vascular diseases, including age-related macular degeneration [AMD]. Right now, patients with blurred vision and an overgrowth of blood vessels are treated with multiple injections to the eye, with the hope of limiting damage. “A high proportion of patients develop resistance against this therapy, which is a big issue,” Gauvrit said. “It's also very costly.”   Mice die quickly without VEGF-A, but zebrafish without it survive — even thrive. Gauvrit wants to know what processes help zebrafish compensate, and where mammalian cells diverge.   Gauvrit said the broader implications of vascular research will have ripple effects in treating lymphedema, strokes, and age-related macular degeneration. “We still discover new things,” Gauvrit said. “Just by serendipity and by randomness, sometimes you can find a bit greater science than when you have a very specific question.”

Readers (and runners) who vibe on the fresh excitement of an author's first novel will love this episode. With host Sarah Bowen Shea, Ellison Weist details these five debuts:The Correspondent: Virginia EvansA Case of Mice and Murder: Sally SmithThe Hounding: Xenobe PurvisThe Slip: Lucas SchaeferThe Eights: Joanna Miller Here's the half-marathon and marathon nutrition program. When you shop our sponsors, you help AMR.We appreciate your—and their—support! Use code INF-AMR to get a gift card good for your next purchase at Selkirk.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Post-puff brain state might not be an emotion, some researchers caution, but the protocol provides a cross-species approach to study emotions.

Ponce de León never found the Fountain of Youth. Andras Bilkei-Gorzo from the University of Bonn in Germany thinks Ponce should have looked at low dose THC. Andras and his team have been giving mice low dose THC and finding some interesting results. Listen to how to get an older mouse to swim to an invisible platform faster, how THC can flip a metabolic switch called mTOR on and off at the same time, and why low dose THC might be better for older people than younger ones. Bidirectional Effect of Long-Term Δ9-Tetrahydrocannabinol Treatment on mTOR Activity and Metabolome- paperA chronic low dose of ∆9-tetrahydrocannabinol (THC)restores cognitive function in old mice- abstractAndras Bilkei-Gorzo - LinkedInTranscripts, papers and so much more at: reefermed.ca

My guest is Dr. Nirao Shah, MD, PhD, a professor of psychiatry, behavioral sciences and neurobiology at Stanford University School of Medicine. We discuss how the brains of males and females differ and how those differences arise from different genes and hormones during fetal development, in childhood and adulthood. We discuss what drives male- versus female-specific behaviors and how hormonal fluctuations across the lifespan, including puberty, the menstrual cycle, menopause and aging – affect behavior, cognition and health. Additionally, we discuss how biology relates to gender identity and the impact of hormone therapies on brain circuits that regulate mating, parenting and social bonding. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Maui Nui: https://mauinuivenison.com/huberman Eight Sleep: https://eightsleep.com/huberman LMNT: https://drinklmnt.com/huberman Function: https://functionhealth.com/huberman Timestamps 00:00:00 Nirao Shah 00:02:11 Mice, Humans & Brain, Biological Conservation 00:05:25 Hormones, Nature vs Nurture 00:07:13 Biological Sex Differences, Chromosomes & SRY Gene, Hormones 00:16:01 Sponsors: Maui Nui & Eight Sleep 00:19:09 Androgen Mutations, Feminization & Masculinization 00:22:04 SRY Gene; Animals & Sexual Trans-Differentiation 00:27:49 Hormones & Biological Brain Differentiation 00:31:22 Congenital Adrenal Hyperplasia, Androstenedione; Stress & Pregnancy 00:35:56 Genes, Brain Differentiation & Sexual Identity; Congenital Adrenal Hyperplasia 00:43:37 Testosterone, Estrogen & Brain Circuits 00:47:27 Sponsors: AG1 & LMNT 00:50:36 Intersex Individuals, Castration 00:52:23 Female Sexual Behavior, Brain, Testosterone & Pheromones 00:57:58 Identify as Heterosexual or Homosexual, Difference in Hormone Levels? 01:00:42 Gender, Sexual Orientation & Hormones; Hormone Replacement Therapy 01:10:21 Aromatization; Steroid Hormones & Gene Expression 01:15:00 Kids & Changing Gender Identity 01:19:05 Sexual Behavior, Refractory Period & Male Brain, Tacr1 Cells 01:21:31 Sponsor: Function 01:23:19 Hypothalamus, Dopamine, Prolactin, Cabergoline, Libido, Dopamine 01:27:05 Brain Circuits, Aggression & Sexual Behavior 01:32:40 Refractory Period; Age, Testosterone & Libido 01:36:07 Tacr1 Cells in Females, Periaqueductal Gray & Innate Behaviors 01:40:00 Parenting Behaviors & Brain Circuits; Pet Dogs 01:43:12 Oxytocin, Pair Bonding, Vasopressin; Biological Redundancy 01:47:22 Libido, Melanocortin, Tacr1 Neurons; GLP-1 Agonists, Clinical Trials; Kisspeptin 01:56:43 Female Brain Changes, Menstrual Cycle, Pregnancy, Menopause; Estrogen; Men & Hormone Fluctuation? 02:04:10 Life Experience Male vs Female, Sex Recognition, Behaviors & Context 02:16:05 Pain Management; Endocrine Disrupters, Gender Identity 02:21:03 Future Projects 02:24:29 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

UCLA's Avishek Adhikari, PhD, presents new research on the role of GABAergic neurons in the brain's periaqueductal gray (PAG) region. Previously studied for their involvement in fear and defensive behaviors, these neurons were found to promote food-seeking behavior when activated—even in fully fed mice. Using calcium imaging and optogenetics, Adhikari's team discovered that these neurons are active during food approach but suppressed during eating. The effect is stronger for high-value foods like chocolate or crickets and depends on the mouse's prior experience with that food. A key finding is that these neurons influence behavior through a specific projection to the zona incerta, a subthalamic region. Rather than signaling hunger, this pathway appears to drive food seeking based on reward value, highlighting a new motivational circuit in the brain. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40444]

UCLA's Avishek Adhikari, PhD, presents new research on the role of GABAergic neurons in the brain's periaqueductal gray (PAG) region. Previously studied for their involvement in fear and defensive behaviors, these neurons were found to promote food-seeking behavior when activated—even in fully fed mice. Using calcium imaging and optogenetics, Adhikari's team discovered that these neurons are active during food approach but suppressed during eating. The effect is stronger for high-value foods like chocolate or crickets and depends on the mouse's prior experience with that food. A key finding is that these neurons influence behavior through a specific projection to the zona incerta, a subthalamic region. Rather than signaling hunger, this pathway appears to drive food seeking based on reward value, highlighting a new motivational circuit in the brain. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40444]

UCLA's Avishek Adhikari, PhD, presents new research on the role of GABAergic neurons in the brain's periaqueductal gray (PAG) region. Previously studied for their involvement in fear and defensive behaviors, these neurons were found to promote food-seeking behavior when activated—even in fully fed mice. Using calcium imaging and optogenetics, Adhikari's team discovered that these neurons are active during food approach but suppressed during eating. The effect is stronger for high-value foods like chocolate or crickets and depends on the mouse's prior experience with that food. A key finding is that these neurons influence behavior through a specific projection to the zona incerta, a subthalamic region. Rather than signaling hunger, this pathway appears to drive food seeking based on reward value, highlighting a new motivational circuit in the brain. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40444]

UCLA's Avishek Adhikari, PhD, presents new research on the role of GABAergic neurons in the brain's periaqueductal gray (PAG) region. Previously studied for their involvement in fear and defensive behaviors, these neurons were found to promote food-seeking behavior when activated—even in fully fed mice. Using calcium imaging and optogenetics, Adhikari's team discovered that these neurons are active during food approach but suppressed during eating. The effect is stronger for high-value foods like chocolate or crickets and depends on the mouse's prior experience with that food. A key finding is that these neurons influence behavior through a specific projection to the zona incerta, a subthalamic region. Rather than signaling hunger, this pathway appears to drive food seeking based on reward value, highlighting a new motivational circuit in the brain. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40444]

UCLA's Avishek Adhikari, PhD, presents new research on the role of GABAergic neurons in the brain's periaqueductal gray (PAG) region. Previously studied for their involvement in fear and defensive behaviors, these neurons were found to promote food-seeking behavior when activated—even in fully fed mice. Using calcium imaging and optogenetics, Adhikari's team discovered that these neurons are active during food approach but suppressed during eating. The effect is stronger for high-value foods like chocolate or crickets and depends on the mouse's prior experience with that food. A key finding is that these neurons influence behavior through a specific projection to the zona incerta, a subthalamic region. Rather than signaling hunger, this pathway appears to drive food seeking based on reward value, highlighting a new motivational circuit in the brain. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40444]

UCLA's Avishek Adhikari, PhD, presents new research on the role of GABAergic neurons in the brain's periaqueductal gray (PAG) region. Previously studied for their involvement in fear and defensive behaviors, these neurons were found to promote food-seeking behavior when activated—even in fully fed mice. Using calcium imaging and optogenetics, Adhikari's team discovered that these neurons are active during food approach but suppressed during eating. The effect is stronger for high-value foods like chocolate or crickets and depends on the mouse's prior experience with that food. A key finding is that these neurons influence behavior through a specific projection to the zona incerta, a subthalamic region. Rather than signaling hunger, this pathway appears to drive food seeking based on reward value, highlighting a new motivational circuit in the brain. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40444]

Rats and mice are using your DC-area home as a permanent bed and breakfast. No biggie, right? Wrong. Rodents might be small, but the damage they can inflict most certainly isn't. Connor's Pest Pros (888-284-6968) shares its insights… and warnings.https://connorspestpros.com/pest-control/rodent-control/ Connor's Pest Pros City: Springfield Address: 5410 Port Royal Rd Website: https://connorspestpros.com/contact/ Phone: +1 888 284 6968

This week on Option Select, we're diving into a whirlwind of gaming and entertainment headlines you don't want to miss: Pokémon teams up with Razer to drop some wild PC peripherals—yes, your setup is about to get way more electric. Taika Waititi is reportedly working on a new Judge Dredd movie—can the king of quirky storytelling do justice to Mega-City One? Spider-Man: Beyond the Spider-Verse hits another delay. We talk expectations, burnout, and whether the wait is worth it. Valve starts removing Adults Only games from Steam—what does this mean for indie devs and content boundaries on the platform? Tune in as we break down what matters, crack a few jokes, and argue over whether Pikachu-themed RGB is genius or a war crime. Hit play, and don't forget to select “Option: Listen.”

Please enjoy this feed drop of Winnie the Pooh by our wonderful friends at literary actual play, Of Mice and Men and Monsters! When you're ready for more, check them out at omamam.com or wherever you listen to podcasts. Learn more about your ad choices. Visit megaphone.fm/adchoices

Sally Smith discusses with Ivan six things which should be better known. Sally Smith spent all her working life as a barrister and later KC in the Inner Temple. After writing a biography of the Edwardian barrister Sir Edward Marshall Hall KC, she retired from the bar to write full time. A Case of Mice and Murder, her first novel, was inspired by the historic surroundings of the Inner Temple in which she still lives and works and was the first in a series starring the reluctant sleuth Sir Gabriel Ward KC. A Case of Mice and Murder was longlisted for the 2025 CWA Whodunnit and Historical Daggers. Her new novel A Case of Life and Limb is available at https://www.waterstones.com/book/a-case-of-life-and-limb/sally-smith/9781526668776. The Temple (Inner and Middle) and its round church, off Fleet Street London. https://www.templechurch.com/royal-charter/the-inns The mysterious ‘Roman ‘ Bath (built 1612) Strand Lane London, next to disused Aldwych Underground Station https://en.wikipedia.org/wiki/Roman_Baths,_Strand_Lane By Grand Central Station I sat down and wept by Elizabeth Smart https://www.lrb.co.uk/the-paper/v13/n04/julian-symons/urgent I capture the castle by Dodie Smith https://www.youtube.com/watch?v=YrGtmuTP_7k The Hawstead Panels in Christchurch Mansion Museum, Ipswich. (Also called Lady Drury's closet') https://ipswich.cimuseums.org.uk/visit/christchurch-mansion/ The Glandford Shell Museum https://www.shellmuseum.org.uk/ This podcast is powered by ZenCast.fm

Brendan shares his thoughts about the movies he watched in May of 2025, and the games that would be good to play alongside those movies.Micmacs (2009)Stuffed Fables (2018)Mice and Mystics (2012)Bill Burr: Drop Dead Years (2025)Joking Hazard (2016)Charty Party (2019)The Mandalorian: Adventures (2024)The In-Laws (1979)[redacted] (2014)The Andromeda Strain (1971)Pandemic Legacy: Season 1 (2015)The Fall Guy (2024)Paddington in Peru (2024)Mice and Mystics (2012)The Lost Expedition (2017)Sinners (2025)Speakeasy Blues (2018)Speakeasy (2025)Panic Station (2011)On Tour (2019)Rock Hard: 1977 (2024)Draft & Write Records (2024)One Night Ultimate Vampire (2016)Till Dawn (2014)The Hunger (2021)What do you think of these films? Share your experience over on boardgamegeek in guild #3269.

"When mice go missing, one unlikely sleuth is determined to sniff out the truth!" During this episode of On the Air with Florenza Intermissions, we're joined by author Sally Smith to discuss her newest book, A Case of Mice and Murder. Mice are missing. Secrets are stirring. And one determined sleuth is on the case! In A Case of Mice and Murder, Sally Smith invites readers into a delightfully cozy world where furry friends vanish, clues are hidden in plain sight, and the smallest details make the biggest difference. Perfect for fans of The Great Mouse Detective and Agatha Christie with a twist, this mystery is as clever as it is heartwarming. #CozyMystery #Whodunit #AnimalMystery #SallySmithAuthor #ACaseOfMiceAndMurder #PodcastInterview #MysteryMonday #BookishChats #OnTheAirWithFlorenza #CozyReads #MouseDetective #FlorenzaDeniseLee

Worked in Mice.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

[This is one of the finalists in the 2025 review contest, written by an ACX reader who will remain anonymous until after voting is done. I'll be posting about one of these a week for several months. When you've read them all, I'll ask you to vote for a favorite, so remember which ones you liked] “The scientific paper is a ‘fraud' that creates “a totally misleading narrative of the processes of thought that go into the making of scientific discoveries.” This critique comes not from a conspiracist on the margins of science, but from Nobel laureate Sir Peter Medawar. A brilliant experimentalist whose work on immune tolerance laid the foundation for modern organ transplantation, Sir Peter understood both the power and the limitations of scientific communication. Consider the familiar structure of a scientific paper: Introduction (background and hypothesis), Methods, Results, Discussion, Conclusion. This format implies that the work followed a clean, sequential progression: scientists identified a gap in knowledge, formulated a causal explanation, designed definitive experiments to fill the gap, evaluated compelling results, and most of the time, confirmed their hypothesis. Real lab work rarely follows such a clear path. Biological research is filled with what Medawar describes lovingly as “messing about”: false starts, starting in the middle, unexpected results, reformulated hypotheses, and intriguing accidental findings. The published paper ignores the mess in favour of the illusion of structure and discipline. It offers an ideal version of what might have happened rather than a confession of what did. The polish serves a purpose. It makes complex work accessible (at least if you work in the same or a similar field!). It allows researchers to build upon new findings. But the contrived omissions can also play upon even the most well-regarded scientist's susceptibility to the seduction of story. As Christophe Bernard, Director of Research at the Institute of Systems Neuroscience (Marseilles, Fr.) recently explained, “when we are reading a paper, we tend to follow the reasoning and logic of the authors, and if the argumentation is nicely laid out, it is difficult to pause, take a step back, and try to get an overall picture.” Our minds travel the narrative path laid out for us, making it harder to spot potential flaws in logic or alternative interpretations of the data, and making conclusions feel far more definitive than they often are. Medawar's framing is my compass when I do deep dives into major discoveries in translational neuroscience. I approach papers with a dual vision. First, what is actually presented? But second, and often more importantly, what is not shown? How was the work likely done in reality? What alternatives were tried but not reported? What assumptions guided the experimental design? What other interpretations might fit the data if the results are not as convincing or cohesive as argued? And what are the consequences for scientific progress? In the case of Alzheimer's research, they appear to be stark: thirty years of prioritizing an incomplete model of the disease's causes; billions of corporate, government, and foundation dollars spent pursuing a narrow path to drug development; the relative exclusion of alternative hypotheses from funding opportunities and attention; and little progress toward disease-modifying treatments or a cure. https://www.astralcodexten.com/p/your-review-of-mice-mechanisms-and

"When mice go missing, one unlikely sleuth is determined to sniff out the truth!" During this episode of On the Air with Florenza, we're joined by author Sally Smith to discuss her newest book, A Case of Mice and Murder. Mice are missing. Secrets are stirring. And one determined sleuth is on the case! In A Case of Mice and Murder, Sally Smith invites readers into a delightfully cozy world where furry friends vanish, clues are hidden in plain sight, and the smallest details make the biggest difference. Perfect for fans of The Great Mouse Detective and Agatha Christie with a twist, this mystery is as clever as it is heartwarming. #CozyMystery #Whodunit #AnimalMystery #SallySmithAuthor #ACaseOfMiceAndMurder #PodcastInterview #MysteryMonday #BookishChats #OnTheAirWithFlorenza #CozyReads #MouseDetective #FlorenzaDeniseLee

Hello friends, this is our SECOND check in - a time of flipping on the mic and catching up with you, sharing a bit of what's going on in my life. And I'd love to hear what's going on in yours, email me at whatifproject.net@gmail.com - I will answer! Here are some links, peace! ... MY BOOK: https://www.amazon.com/Emerging-Rubble-Stories-Shattered-Relationships/dp/B0C7T5TJD4/ref=sr_1_1?crid=2B051GGV2WCSI&keywords=glenn+siepert&qid=1700157759&sprefix=glenn+%2Caps%2C399&sr=8-1 SUBSTACK / BLOG: https://whatifproject.substack.com/ ART STUDIO: https://www.whatifproject.net/art SUPPORT THE SHOW: https://www.whatifproject.net/support  SUPPORT MY ART: https://www.whatifproject.net/checkout/donate?donatePageId=67e862dd7198a645f85a4bdc

Is your garage more of a storage locker than a place to park your car? In this episode of https://FixItRadio.com, John Rush launches a timely deep dive into the cluttered corners of our homes—starting with the garage. Why do we hold onto broken mounts, old paint cans, or spare parts we haven't touched in years? Could all that “just-in-case” inventory be costing you space, money, and even security? As John and Larry Unger dig deeper, they reveal just how easily clutter can turn into chaos. Are you unknowingly creating the perfect rodent playground? From labeling and dating items to utilizing $5 clear plastic bins and QR-coded storage systems, the episode offers modern tools and clever hacks to keep your space rodent-proof and organized. It's not just about tidying up—it's about making your garage functional again. Then comes a jaw-dropping twist: a listener calls in to reveal that mice stashed 25 pounds of cat food inside a drainage tube—right under the noses of the barn cats! The story sparks a bigger conversation with Jeff about how clutter, old tools, and outdated equipment might be less treasure and more trash. Are your corded drills, air nailers, and vintage gear now obsolete in a cordless world? From nostalgic holdouts to cutting-edge upgrades, this episode is part how-to, part reality check—and it just might inspire you to take back your space.

In this episode we talk with Scott deMoulin the CEO of www.earthkind.com Earthkind has non poison pest control products that can keep rodents out of your cars, trucks, RV, and boats. If you order from Earthkind, and put "protect" in the order form, you can save a little money. BTW this Volvo is quite the car. We also get to talk with some of our longtime listeners. 

In this episode we talk with Scott deMoulin the CEO of www.earthkind.com Earthkind has non poison pest control products that can keep rodents out of your cars, trucks, RV, and boats. If you order from Earthkind, and put "protect" in the order form, you can save a little money. BTW this Volvo is quite the car. We also get to talk with some of our longtime listeners. 

Mice and the Ice Capade by Carley Smith Amazon.com The poor family of mice was exhausted following a long summer of storing rice for the winter months. Together, they learned ways to create fun and simple ways to use things they had and things they found so the whole neighborhood could enjoy a huge celebration on ice.

Four years ago, I brought Victor on the show while navigating my own fertility challenges and exploring deuterium depletion. He told me, “It's going to work,” and now I'm back with my two-and-a-half-year-old son.In this episode, we revisit the science behind deuterium-depleted water, how it supports mitochondrial function, hormones, and overall metabolic health, and why it's not the same as just changing your diet. We also cover who depletion might be right for, myths around DIY methods, and how to get started safely.→ Check Out Litewater |  Click Here & use code SarahK for 10% off Topics Discussed: → What is deuterium depletion and how does it affect fertility?→ Can deuterium-depleted water improve mitochondrial health?→ Is it possible to make deuterium-depleted water at home?→ How does deuterium impact hormones and metabolic function?→ Who should consider trying a deuterium depletion protocol?Timestamps:→ 00:00:00 - Introduction → 00:03:06 - Deuterium depletion → 00:07:20 - Importance of lifestyle change → 00:08:35 - Basal body temperature → 00:12:11 - Chronic low temperature → 00:14:54 - Parasites & health cleanses → 00:19:24 - Perimenopause → 00:22:48 - Aging & Deuterium → 00:28:29 - 3 weeks of a good habit → 00:30:44 - Dangers of sleep aids → 00:33:10 - Insulin & deuterium depletion → 00:36:21 - Deuterium depletion and weight loss→ 00:40:35 - Hormones & mitochondria → 00:42:01 - Coconut water & dry fasting → 00:45:24 - Detox pathways → 00:50:23 - Shifting away from Big Pharma→ 00:56:39 - Mice studies & stress resilience → 00:59:53 - Antiaging science → 01:05:03 - Oversupplementation → 01:11:04 - Listening to your intuition → 01:17:51 - Deuterium protocol → 01:25:22 - Importance of discipline Show Links:→ What is the real cause of aging? Deuterium depletion with Victor Sagalovsky - Litewater→ Get the Deuterium Guide & Food ListSponsored By:→ Tropscriptions | There's a completely new way to optimize your health. Give it a try at troscriptions.com/SARAHK, or enter SARAHK at checkout for 10% off your first order.→ Bon Charge| Click here & use code for SARAHKLEINER for 15% off storewide.Check Out Victor: → Check Out Litewater |  Click Here & use code SarahK for 10% off → Instagram→ ResourcesThis video is not medical advice & as a supporter to you and your health journey - I encourage you to monitor your labs and work with a professional!________________________________________My free product guide with all product recommendations and discount codes:https://s3.amazonaws.com/kajabi-storefronts-production/file-uploads/sites/2147573344/themes/2150788813/downloads/eac4820-016-b500-7db-ba106ed8583_2024_SKW_Affiliate_Guide_6_.pdfCheck out all my courses to understand how to improve your mitochondrial health & experience long lasting health! (Use code PODCAST to save 10%) -  https://www.sarahkleinerwellness.com/coursesSign up for my newsletter to get special offers in the future! - https://www.sarahkleinerwellness.com/contact

Yes! We've done it! Another slightly aimless amble through some recent episodes as Tom and Beth take on huge topics including MICE, WASPS and PERCUSSION.Some of the products talked about today include:COMPOST BIN LINERS (for the freezer, if you're cool)BUNTINGHUMANE MOUSE TRAPSandMAP ERRORS FOR DADSThat's it for today - make sure you're fully subscribed up for some Pete Firman action next Tuesday. Till then have a great lifeToast xxTikTok Instagram YouTube New Episodes every Tuesday and Thursday Hosted on Acast. See acast.com/privacy for more information.

A lady lost an arm after a lioness attacked her at the Darling Downs Zoo in Queensland, Australia. Scientists are messing with mice genes to change their vocal DNA - so they can speak! They better never do this to house cats. A man was scammed out of hundreds by a fake Jennifer Aniston who told him 'she loved him'. Do you care if a band and its music is AI generated? Velvet Sundown is an AI band, and they're crushing it on Spotify. The worst boyfriend on the planet didn't stop competing in a workout competition when his girlfriend passed out and needed medical attention. How would you handle a coworker stealing your lunch? Epstein, Musk, and Trump - oh my!

Welcome to Dome Dump—raw, loud, and shit I think you need to hear. This is me, the mic, y'all listening—no notes, no mercy, and whatever's bouncing around in my dome. Thanks for being here. Take what you want, leave the rest. Mic's hot. I'm caffeinated. And today, I'm tearing into the truth about AI—no fluff, no filters. We're not talking about how “cool” ChatGPT is. We're talking about what happens when the tool starts questioning the hand holding it.

Here's How to get rid of those pesky visitors   Support the show www.patreon.com/worldaroundewe

Welcome to Dome Dump—raw, loud, and shit I think you need to hear. This is me, the mic, y'all listening—no notes, no mercy, and whatever's bouncing around in my dome. Thanks for being here. Take what you want, leave the rest. Mic's hot. I'm caffeinated. And today, I'm tearing into the truth about AI—no fluff, no filters. We're not talking about how “cool” ChatGPT is. We're talking about what happens when the tool starts questioning the hand holding it.

What if joy became the most important metric when we organised events? Or, to put it another way, why are so many events uninspiring and not very joyful?Episode SummaryOn this episode, I'm joined by event strategist, educator, and author Tahira Endean to explore a provocative question: what if we measured events not just by financial metrics, but by the joy they deliver?Drawing from her new book Our KPI is Joy: How Live Events Catalyze Happiness, Productivity and Trust, Tahira shares deep insights from decades of experience curating and designing events at scale, including her work with IMEX, one of the largest global gatherings in the meetings and events industry. We discuss why so many events feel soul-crushingly mediocre and how that reflects a fundamental misunderstanding of what people really need when they come together. Tahira challenges the industry's obsession with surface-level logistics and proposes a reorientation around human experience.She unpacks everything from the science of connection and discomfort to the power of design, food, space, and unexpected joy to foster trust and productivity. Whether you're an event professional, a business leader, or simply someone who's sat through one too many lifeless conferences, this conversation will challenge how you think about convening people. We discuss beanbags, sound baths, shrimp, secret handshakes, and how small design decisions can profoundly impact how people feel, learn, and connect. And that's what makes joy — not an emoji or indulgence — but a powerful performance indicator.Guest Bio: Tahira EndeanTahira is an experienced event strategist, educator, and co-founder of Strategy Table. She serves as Head of Programme for IMEX, where she curates content for two of the world's largest MICE (Meetings, Incentives, Conventions, and Exhibitions) industry gatherings in Frankfurt and Las Vegas. With over three decades in the events industry, Tahira has developed a reputation for her forward-thinking approach to event design and human-centric experiences. She teaches event strategy and design, is a passionate advocate for experiential innovation, and brings a behavioural lens to the way we bring people together. She believes in the power of micro-moments, psychological safety, and events as catalysts for human connection and organisational trust.AI-Generated Timestamp Summary0:00:02 - 0:14:48: Maximizing Event Joy for ProductivityThe episode kicks off with a discussion on how joy can be a key performance indicator (KPI) for events. Tahira Endeen, an experienced event strategist, talks about why many events end up being mediocre and how small design changes can significantly enhance the experience. The conversation highlights the importance of joy in fostering happiness, productivity, and trust during gatherings, challenging the traditional business mindset to value joy as much as other KPIs. 0:14:48 - 0:29:08: Designing Events for Human ConnectionThis segment delves into the principles of intentional event design. Tahira and the host explore how creating environments that balance comfort and stimulation can lead to more meaningful interactions and learning experiences. They discuss examples like the 11th International Conference on AIDS, where well-designed events led to groundbreaking innovations. The focus is on nurturing individual experiences over catering to the masses.0:29:08 - 0:37:32: Designing Thoughtful & Engaging EventsThe focus here is on fostering connections and joy in professional events through thoughtful design. Strategies like facilitating introductions by senior managers and organising diverse breakout sessions are explored. The segment underscores the importance of measuring engagement and joy, emphasizing a human-centered approach that considers attendees' needs and enhances productivity and satisfaction.0:37:32 - 0:49:24: Embracing Experimentation and FailureTahira shares insights on the value of experimentation and adaptability in event planning. Through a personal anecdote, she illustrates how innovative ideas, initially met with scepticism, can yield significant benefits. The conversation encourages making small changes, embracing failures as learning opportunities, and maintaining a proactive attitude to achieve unexpected successes. 0:49:24 - 1:01:30: Navigating Event Chaos for SuccessThe episode explores the beauty of embracing imperfections in event planning. Tahira and the host discuss how handling mistakes with grace and humour can add charm to events. They advocate for flexibility in event processes to enhance experiences for both speakers and attendees, maintaining the magic even amidst logistical challenges.LinksIMEX Events - https://imexevents.com/Strategy Table - https://strategytable.co/Our KPI is Joy Book - https://www.amazon.com/Our-KPI-Joy-Happiness-Productivity-ebook/dp/B0DXVX6XX8Tahira on LinkedIn - https://www.linkedin.com/in/tahira-endean-msc-citp-cmp-ced-918a868/?

We have uncovered a case of sabotage! Who is to blame? The British? Jackson? Mice? It's a mystery! The Mariners were off yesterday and it showed! :30- Mariners Morning After It was a sloppy 6-3 loss for the M's. Hitting into double plays, missed fly balls at the wall and more. What happened? :45- The Kraken picked up free agents Ryan Lindgren & Matt Murray yesterday. They just can't help making moves and we love it! See omnystudio.com/listener for privacy information.

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In this episode, Therese Markow and Dr. Cheryl Hawkes discuss the increasing scientific evidence that maternal obesity affects the developing fetal brain.  While many of the effects manifest early, in infant temperament and childhood cognitive (IQ) decrements, other effects do not show up until years later, in adult psychiatric and neurodegenerative problems.  The physical bases for these changes in fetal brains are also clearly evidenced in laboratory model systems, such as mice, where the maternal diets can be controlled, and the offspring not only can be given behavioral tests, but their brains can be dissected to reveal the changes in the blood vessels caused by obese mothers.    Key Takeaways: Children born to obese mothers have lower IQs and poorer motor, spatial, and verbal skills. Mice and rodents have similar brain development to humans, which is why rodent study models are so beneficial to science. Brain maturation takes many years. Your brain is fully formed at birth, but continues to mature and change into your mid-twenties.   "Because of the rise in obesity globally, a lot of people have started to look, rather than looking at famine…, to now shift our attention to looking at the long-term effects of obesity because 30% of women around the world, over the age of 18, are now considered to be obese." —  Dr. Cheryl Hawkes   Connect with Dr. Cheryl Hawkes:  Lancaster University Profile: Dr. Cheryl Hawkes     Connect with Therese: Website: www.criticallyspeaking.net Threads: @critically_speaking Email: theresemarkow@criticallyspeaking.net   Audio production by Turnkey Podcast Productions. You're the expert. Your podcast will prove it.  

In this episode of The Homeowners Show, we're getting our hands dirty—in the best way possible. First, we break down California's latest Defensible Space initiative and what it means for homeowners looking to protect their property from wildfires. Learn the new rules, how to comply, and smart ways to turn your yard into a fire-safe zone without sacrificing curb appeal.   Then we shift gears (and gears snap!) as we talk classic mouse traps. Whether you're battling a sneaky kitchen invader or just prepping for winter, we'll walk you through how to properly set, place, and maintain traps that actually work—plus some pro tips to keep rodents from coming back. Lone Star Appliance Repair - 936-647-2364 – Give them a call for all your appliance repair needs. Their staff is the best in the business and can help get you squared away with all of your appliance repairs.   True Texas Solar – 936-286-8325 – Give True Texas Solar a call if you would like to learn how your home or business would benefit from solar. There are tons of incentives available, and they are experts in owning your energy!   Krazy Klean – never scrub your toilet again with this chemical-free solution for your toilet.   Buy a Homeowners Show T-Shirt!   Subscribe to our YouTube Channel   The Homeowners Show Website The Homeowners Show Facebook Page Instagram @homeownersshow Twitter @HomeownersThe   Info@homeownersshow.com    Sustained Growth Solutions – Design a lead generation system specifically for your business so that you never have to search for leads again! We are a full digital marketing agency.

We are allowed one non bookish episode a year, right?Links mentioned:"Tech Gone Wrong" Books: https://bookshop.org/lists/tech-gone-wrong"Tech Gone Wrong" Audiobooks: https://libro.fm/playlists/9673?bookstore=bissettbooksSupport The Podcast:Join our patreon and become a Dust Jacket! patreon.com/booksunboundSign up to the bookmark subscription! https://store.dftba.com/products/books-unbound-bookmark-subscriptionOur beautiful merch: https://store.dftba.com/collections/books-unboundAriel's T-shirt: https://store.dftba.com/collections/bissett-books/products/im-thinking-about-books-t-shirtFollow us on instagram: https://www.instagram.com/books_unbound/Need Info or Some Books?Buy books with our affiliate link: https://bookshop.org/shop/BooksUnboundAll the books we mentioned in this episode: https://www.booksunboundpodcast.com/booksSubmit your book requests at booksunboundpodcast.comUse our affiliate link to get 2 audiobooks for the price of 1! https://tidd.ly/3dyW1XwOur Patrons:A special thanks to our Gold Foil Team on Patreon: Abigail, Adriane, Alex, Bellanora, Brittany, Bronte, Candis, Christina, Claire, Debra, Diana, Gene, Hannah, Inbar, Jessie, Jill, Karina, Livi, Luna, Megan, Michelene, Myriam, Nicole, Phoebe, Roisin, Sherralle, Tiffany, Tina, Vanessa, Zoe!

Ben Lamm is an entrepreneur and the founder and CEO of Colossal Biosciences. That's the genetic engineering company making headlines for its bold mission – bringing extinct species back to life. From dire wolf pups to woolly mice, Colossal’s breakthroughs have sparked awe and controversy. Lamm sits down with Oz to unpack the science behind de-extinction, the ethical questions it raises, and what it could mean for the future of conservation.See omnystudio.com/listener for privacy information.

Story at-a-glance A high-fat diet makes it easier for breast cancer to spread by activating clotting cells, increasing inflammation and altering blood vessels in ways that help tumors grow Mice on high-fat diets had nearly five times more cancer cells in their lungs, even when their tumors were the same size as leaner mice A high-fat diet increased fibronectin, which acts as "molecular glue" helping cancer cells attach to blood vessels, while obesity increases inflammatory compounds that worsen this buildup Switching to a normal-fat diet for just seven days significantly reduced clotting activity, fibronectin buildup and the number of cancer cells lodging in the lungs Eliminating vegetable oils and reducing total fat intake to 30% to 40% of daily calories lowers inflammation and reduces your risk of cancer spread