Podcasts about Biology

In December, we're airing the top five most-played episodes of the year - and this conversation with Macee Huseman easily earned its spot! As a one-woman science department juggling six preps and three kids at home, Macee balances a heavy workload while still staying sane. We dig into everything from engaging students across multiple science subjects to using labs, routines, and even candy to spark curiosity. She also shares practical strategies for classroom management, grading, handling varied math skills, and prepping labs without the overwhelm!➡️ Show Notes: https://itsnotrocketscienceclassroom.com/episode212Resources Mentioned:Take the 2026 SSS Podcast SurveyBe a guest in 2026 on the SSS podcast! INRS Biology Curriculum – FULL YEAR Bundle INRS Physical Science (IPC) Curriculum – FULL YEAR BundleDownload your FREE Classroom Reset Challenge.Take the Free Labs When Limited virtual PD courseSend me a DM on Instagram: @its.not.rocket.scienceSend me an email: rebecca@itsnotrocketscienceclassroom.com  Follow, rate, and review on Apple Podcasts.Follow, rate, and comment on Spotify.Related Episodes and Blog Posts:Episode 125, Teaching AP Biology with Guest Beth HinesEpisode 176, Teaching AP Biology, Exam Review, FRQ Prep, and More with Tiffany of AP Bio PenguinsEpisode 190, Student Mastery, Switching Schools, and Teaching Chemistry with Heather BonannoEpisode 191, Engaging Students, Serving ELLs, and Teaching Earth Science with Becca of Science Lessons That RockEpisode 200, Ask Me Anything! Going Over Work, NGSS, Labs, And More!

Send us a textHow dietary polyunsaturated fats, especially omega-6 from seed oils, influence inflammation & heart health.Topics Discussed:Polyunsaturated fatty acids (PUFAs): Omega-6 from seed oils like safflower and corn can convert to pro-inflammatory molecules, while omega-3s produce resolving ones; imbalance biases toward chronic inflammation.Inflammation regulation: Acute inflammation aids healing but requires active “on” and “off” signals from lipid mediators; chronic inflammation arises from excess omega-6, delaying resolution.Heart health & diet: High omega-6 diets worsen post-heart attack outcomes in mice by elevating pro-inflammatory lipids.Evolution & historical context: PUFAs are essential but naturally balanced in pre-industrial diets; modern processing skews ratios, contributing to diseases, as shown in early rat experiments needing minimal fats for survival.Aging & lifestyle factors: Excess omega-6 exacerbates inflammation in older mice; sleep, exercise, and balanced fats are crucial for metabolic health and enzyme function in processing lipids.Cannabis & omega-6 interaction: In mice on high omega-6 diets, CBD-rich cannabis smoke reaches the heart quickly, suppresses immune response, and weakens cardiac strain, unlike in balanced-diet controls.Genetic models: FAT-1 mice converting omega-6 to omega-3 show better healing and neuroprotection; FAT-2 mice doing the opposite exhibit liver fibrosis and metabolic issues, highlighting omega-6 excess harms.Practical Takeaways:Balance omega-6 and omega-3 intake by reducing seed oils in processed foods and increasing sources like fish or algae to support inflammation resolution and heart health.Monitor and adjust fat intake with age, as older individuals are more sensitive to omega-6 excess leading to immune dysregulation.Avoid combining high omega-6 diets with smoking, as it may impair immune and cardiac responses based on animal data.About the guest: Ganesh Halade, PhD is a cardiovascular scientist and associate professor at the University of South Florida Morsani College of Medicine.*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

The Darwin-Wallace framework stands tall, but there are places where the seams show, where life presses back with its own kind of intention. Scott Turner guides us through those overlooked corners, tracing the ideas that slipped between theory and experience. We find organisms not as passive machines, but as players in a deeper, older rhythm. And in that recognition, the story of evolution widens into something more awake, more alive.PATREON https://www.patreon.com/c/demystifysciPARADIGM DRIFThttps://demystifysci.com/paradigm-drift-showHOMEBREW MUSIC - Check out our new album!Hard Copies (Vinyl): FREE SHIPPING https://demystifysci-shop.fourthwall.com/products/vinyl-lp-secretary-of-nature-everything-is-so-good-hereStreaming:https://secretaryofnature.bandcamp.com/album/everything-is-so-good-here00:00 Go! 00:09:00 Evolution's Philosophical Foundations 00:12:00 Linnaeus and Early Taxonomy 00:18:00 Idealism vs. Darwinian Thought 00:23:27 Ideological Divide in Evolutionary Theory 00:25:03 Early Evolutionary Inquiry and Natural Theology 00:29:00 Darwin's Voyage and Observations 00:33:57 Intelligence, Purpose, and Evolution 00:37:30 Geological and Evolutionary Gradualism vs. Catastrophism 00:41:40 Darwin & Wallace: Collaboration and Legacy 00:46:34 Mutationism vs. Natural Selection 00:49:44 Reconciling Mutationism and Darwinism 00:53:00 The Eclipse of Darwinism and Rediscovery of Mendel 00:56:14 Evolution, Loss of Purpose and Agency 01:00:30 Darwin's Pangenesis Theory 01:09:06 Biology, Culture, and Evolution 01:11:07 Evolutionary Theories and Future Directions #history, #consciousness, #evolution, #criticalthinking,#physicspodcast, #philosophypodcast MERCH: Rock some DemystifySci gear : https://demystifysci-shop.fourthwall.com/AMAZON: Do your shopping through this link: https://amzn.to/3YyoT98DONATE: https://bit.ly/3wkPqaDSUBSTACK: https://substack.com/@UCqV4_7i9h1_V7hY48eZZSLw@demystifysci RSS: https://anchor.fm/s/2be66934/podcast/rssMAILING LIST: https://bit.ly/3v3kz2S SOCIAL: - Discord: https://discord.gg/MJzKT8CQub- Facebook: https://www.facebook.com/groups/DemystifySci- Instagram: https://www.instagram.com/DemystifySci/- Twitter: https://twitter.com/DemystifySciMUSIC: -Shilo Delay: https://g.co/kgs/oty671

Exercise switches on waves of genes, proteins and metabolites that boost energy production, repair tissues and stabilize blood sugar, helping you feel more focused and resilient Endurance and strength training activate different molecular pathways, allowing you to choose routines that match your goals for stamina, fat burning or metabolic control Movement improves the signals your bloodstream uses to coordinate immunity, inflammation and stress responses, which supports steadier moods and better overall health Your muscles release tiny molecular "packages" during activity that influence distant organs like your brain and liver, creating whole-body benefits you can't get from sitting still Short, consistent bouts of movement throughout the day reinforce healthier cellular signaling, making it easier to maintain energy, manage weight and stay metabolically flexible

Hosts Dr. Mike Brasher and Chris Jennings are joined by Dr. Mark Lindberg, professor at University of Alaska, Fairbanks, Institute of Arctic Biology to discuss the ramifications of band targeting and how targeting banded birds can have repercussions on the data. Listen now: www.ducks.org/DUPodcastSend feedback: DUPodcast@ducks.orgSPONSORS:Purina Pro Plan: The official performance dog food of Ducks UnlimitedWhether you're a seasoned hunter or just getting started, this episode is packed with valuable insights into the world of waterfowl hunting and conservation.Bird Dog Whiskey and Cocktails:Whether you're winding down with your best friend, or celebrating with your favorite crew, Bird Dog brings award-winning flavor to every moment. Enjoy responsibly.

Steve Wunker, the Managing Director of New Markets Advisors, a global consulting firm that helps ambitious innovators find their next wave of growth joins Enterprise … Read more The post Why AI Initiatives Are Falling Flat and the Biology Lesson That Can Save Them appeared first on Top Entrepreneurs Podcast | Enterprise Podcast Network.

Chances are that when most of us think of spinosaurs our minds will turn to the hulking, predatory sail-backed dinosaur that famously took down a T. Rex in the Jurassic Park movies. But thanks to their highly fragmented fossil records, in the real world, our knowledge of these fascinating, ancient creatures is far from complete. Where did they live? How did they live? And what did they really look like? In today's episode, we're joined by David Hone, a palaeontologist based at Queen Mary University of London, and Mark P. Witton, a palaeontologist and paleoartist based at the University of Portsmouth, to talk about their latest book, Spinosaur Tales, The Biology and Ecology of the Spinosaurs. They tell us how palaeontologists piece together details of dinosaurs' appearances and behaviours by painstakingly poring over fossil records, why we shouldn't believe everything we see in the movies, and why there's still so much to learn about these mysterious, and at times controversial, beasts. Learn more about your ad choices. Visit podcastchoices.com/adchoices

In this high-impact solo episode, Darin strips away the noise, hacks, and hype to deliver a clear, no-BS roadmap for transforming your body, brain, energy, and direction in life. This is a straight-talk breakdown of the 5 foundational habits that matter most — the habits backed by science, ancient wisdom, and Darin's decades-long experience living this work every day. Expect practical steps, micro-experiments, timing rules, and the mindset needed to reclaim sovereignty in a world full of distraction. If you're ready to build a stronger, clearer, more powerful version of yourself… this is the episode.     What You'll Learn 00:00 – Welcome to SuperLife How this podcast helps you build sovereignty through real habits, real truth, and real practices. 03:07 – Why this episode is different Darin lays out the mission: habits, hacks, hard truths — without dogma or fluff. 03:44 – The 5 foundational moves that change your biology A preview of the metabolic, physical, mental, and behavioral levers that create huge shifts.     1. METABOLIC EDGE — Eat Like You're Building a Future 04:03 – Terrain theory + why your food timing matters How altering the internal environment of your cells changes everything. 05:02 – The two levers that unlock metabolic health Time-restricted eating + plant-forward whole foods. 05:23 – Compressing your eating window Why 8–10 hours is ideal, how it improves glucose, insulin, weight, and inflammation. 06:18 – Practical weekly ramp-up Week 1: 12 hours. Week 2: 8–10 hours. Simple, sustainable, achievable. 07:10 – Darin's personal eating window 10 a.m. to 6 p.m. — and why eating earlier aligns with digestive fire.     2. MOVEMENT THAT MATTERS — Strength Is Survival 11:04 – Why strength training is non-negotiable Muscle protects metabolism, bone density, insulin sensitivity, and longevity. 11:51 – What the evidence says Huge cohort studies show strength training reduces all-cause mortality. 12:23 – The perfect weekly formula 3x/week compound lifts + daily movement + micro-bursts every hour. 13:06 – Real-life practicality Darin's routine of walking, sprinting dogs, mountain biking, and breaking up the day with movement.     3. SLEEP — The Ultimate Biological Reset 16:26 – The truth everyone ignores You cannot out-supplement or out-biohack poor sleep. 16:40 – The real impact of chronic sleep loss Cognition, memory, hormones, emotional regulation — all decline. 17:37 – The universal rule: consistent timing Same bedtime ± 30 minutes, every night. 17:52 – 60-minute wind-down protocol Screens off, light down, nervous system softening. 18:32 – Using sauna as a down-regulation tool Infrared benefits + why Darin does it twice a day in winter.     4. MINDSET & CONSCIOUSNESS — Your Attention Is Your Power 20:00 – Why optimization fails without attention training You can master food, workouts, and sleep — but scattered attention destroys progress. 20:48 – Darin's morning protocol Water → elixir → infrared pad → meditation → visualization → journaling. Every day. Everywhere. 21:01 – Meta-analysis proof Meditation reduces anxiety, depression, stress — and rewires your brain. 21:23 – The perfect 10-minute breathwork formula 5–5–5–5 or 4–4–4–4 cycles for nervous system reset. 21:56 – Journaling as medicine Stream-of-consciousness to activate clarity and emotional release.     5. WEALTH — Treat Your Time Like Capital 22:36 – Redefining wealth It's not money — it's your magnetism, output, relationships, and purpose. 23:16 – The compounding effect of tiny decisions Time batching, micro-actions, and protecting your attention from the social media attention economy. 24:02 – Mini productivity framework 90 seconds → 3 important calls. Every Friday → 1 paragraph on what scaled this week. 25:14 – Darin's post-meditation rule No scrolling — replace with proactive actions: reading, outreach, Patreon replies.     FINAL TAKEAWAYS 26:02 – The master checklist: • Time-restricted eating • Plant-focused meals • Resistance training • Daily meditation • Consistent sleep • Sauna recovery • Treating time like capital 26:11 – The real danger Chasing hacks before mastering fundamentals leads to burnout, confusion, and stress. 27:58 – Your power is in the basics These are simple, accessible, and life-changing. 28:04 – Closing message "Have your best Super Life Day ever."     Thank You to Our Sponsors Our Place: Toxic-free, durable cookware that supports healthy cooking. Go to their website at fromourplace.com/darin and get 35% off sitewide in their largest sale of the year. Manna Vitality: Go to mannavitality.com/ and use code DARIN12 for 12% off your order.     Join the SuperLife Community Get Darin's deeper wellness breakdowns — beyond social media restrictions: Weekly voice notes Ingredient deep dives Wellness challenges Energy + consciousness tools Community accountability Extended episodes Join for $7.49/month → https://patreon.com/darinolien     Find More from Darin Olien: Instagram: @darinolien Podcast: SuperLife Podcast Website: superlife.com Book: Fatal Conveniences     Key Takeaway "Your biology changes when your decisions change. Nail your sleep, nail your strength, honor your attention, and treat your time like capital — and you will build a Super Life from the ground up."     Bibliography Time-restricted eating (human RCTs / reviews) — Wilkinson et al., 10-hour TRE reduced weight and improved cardiometabolic markers (2019). PMC  Intermittent fasting / metabolic health review — comprehensive reviews showing metabolic switching benefits. PMC+1  Plant-forward/vegetarian diets & cardiometabolic outcomes — BMJ/Nutrition reviews and JAMA network evidence showing improved CVD risk markers and metabolic benefits. BMJ Nutrition+1  Sleep and cognition / brain health — Nature/Harvard coverage & meta-analyses: short sleep impairs cognition and links to amyloid processes. Nature+1  Resistance training & mortality / physical function — systematic and cohort evidence that muscle-strengthening activity lowers risk and preserves function. British Journal of Sports Medicine+1  Mindfulness & mental health meta-analysis — Goyal et al. 2014 and subsequent meta-analyses showing reductions in anxiety/stress. PubMed+1  Sauna bathing and cardiovascular outcomes — JAMA Internal Medicine / Mayo Clinic Proceedings reviews on sauna and lower CVD risk signals.

Host Katie Burke sits down with carver Cameron McIntyre in his Virginia studio to discuss his upcoming solo auction, Portrait of a Farm, presented by Guyette & Deeter. Cameron shares insights into the artistry and methodology behind his decoys, while also opening up about the collection of paintings featured in the auction—his largest showing to date. The conversation explores his history with landscape painting, the inspirations that fuel his work, and how this milestone event blends tradition, craftsmanship, and personal vision.Check out our previous conversation with Cameron here:Ep 353, Collector Series: Master Decoy Carver, Cameron McIntyreListen now: www.ducks.org/DUPodcastSend feedback: DUPodcast@ducks.orgSPONSORS:Purina Pro Plan: The official performance dog food of Ducks UnlimitedWhether you're a seasoned hunter or just getting started, this episode is packed with valuable insights into the world of waterfowl hunting and conservation.Bird Dog Whiskey and Cocktails:Whether you're winding down with your best friend, or celebrating with your favorite crew, Bird Dog brings award-winning flavor to every moment. Enjoy responsibly.

In this episode, we examine why arts education often maintains higher standards even as liberal arts programs shrink in schools and universities, and what students lose when curriculum narrows to job training. We discuss how platforms like X are adding country-of-origin labels to identify foreign influence and bot activity, and highlight the “foolishness of the week” involving the controversy over the “world's strongest woman” and the broader questions it raises about biology and competitive fairness. We turn to Australia's proposal to ban social media for kids under sixteen, exploring the practical limits of age verification, the tension between parental authority and government regulation, and why teens remain vulnerable to algorithmic manipulation. We close by considering where society should draw age boundaries, how platforms shape behavior, and what genuine responsibility looks like in the digital age. 00:00 Introduction and Overview 00:29 The State of Arts Education Today 02:57 Why Liberal Arts Are Disappearing From Schools 05:45 What a Liberal Arts Education Actually Provides 06:59 X Adds Country-of-Origin Labels 09:56 Foolishness of the Week: “World's Strongest Woman” 11:31 Biology, Fairness, and Competition in Sports 17:51 Age Rules and Arbitrary Lines 20:53 Australia's Proposed Social Media Ban for Under-16s 23:21 Why Age Verification Won't Work in Practice 26:08 Should the Government Regulate Children's Social Media Use? 27:32 Algorithmic Bubbles and Teen Vulnerability 33:45 96% of Australian Children Ages 10-15 Use Social Media 34:55 Where to Draw the Line: 13, 16, or 18? 39:34 Parental Responsibility vs. Government Control 46:34 Closing Thoughts on Freedom, Parenting, and Policy Learn more about your ad choices. Visit podcastchoices.com/adchoices

Science editor Ian Sample sits down with co-host Madeleine Finlay and science correspondent Hannah Devlin to hear about three eye-catching stories from the week, including a study showing that the brain has five ‘eras', with adult mode not starting until our early 30s. Also on the agenda is new research showing the shingles vaccine not only protects against dementia but could actually slow its progress, and a paper exploring how ants sacrifice themselves when they become infected with pathogens to protect their healthy relatives. Help support our independent journalism at theguardian.com/sciencepod

Dr. Marc Lewis is a neuroscientist, psychologist, and psychotherapist who taught developmental psychology at the University of Toronto for over 20 years. He's the author of "Memoirs of an Addicted Brain" and "The Biology of Desire: Why Addiction Is Not a Disease". Drawing from both his personal recovery journey and decades of research, Dr. Lewis offers a revolutionary perspective on addiction neuroscience.WHAT WE DISCUSSEDNEUROSCIENCE INSIGHTS:Why dopamine isn't a "pleasure chemical" and what it actually does in addictionThe real difference between healthy learning and addictive learningHow the striatum, amygdala, and prefrontal cortex create compulsive behaviorWhy different types of emotional pain lead to different substance choicesThe neuroplasticity principle: "what fires together, wires together"THERAPEUTIC PERSPECTIVES:Why addiction is NOT a chronic relapsing brain diseaseInternal Family Systems (IFS) therapy and how it heals addictionThe three parts: The Critic, The Firefighter, and The Exile (inner child)Why self-compassion is non-negotiable for recoveryHow to talk to the different "parts" of yourselfMark's approach with his 20-30 weekly therapy clientsPERSONAL WISDOM:Mark's 8-10 year journey through heroin and cocaine addictionHis daily practices for staying present and connected at age 74How he faced a terrible year (divorce, family estrangement, illness) with IFS toolsWhy connection (not sobriety) is the opposite of addictionPractical steps for breaking bad habits and building new neural pathwaysPARENTING & PREVENTION:How to talk to kids about drugs in a way they'll actually listenWhy loneliness is the biggest risk factor for addictionThe critical importance of movement, sleep, and feeling understoodWhy some childhood experimentation is actually healthyKEY INSIGHTS:"The opposite of addiction is not sobriety. It's connection" - Johann Hari"We have different parts of our personality, and they often polarize in addiction.""You can heal at any age—with presence, breath, and self-love.""Stop thinking of addiction as a disease. It's learned behavior."RESOURCES MENTIONEDBOOKSThe Biology of Desire: Why Addiction Is Not a Disease" by Marc Lewis (available in Romanian: "Biologia Dorinței")Memoirs of an Addicted Brain" by Marc Lewis"Chasing the Scream" by Johann HariPROGRAMS & PEOPLELiminal Learning program by Isabela Granic Dr. Gabor Maté - Compassionate InquiryDr. Dick Schwartz - Internal Family Systems (IFS) therapyJohann Hari's TED Talk: "The Opposite of Addiction is Connection"Sat Dharam Kaur - Compassionate Inquiry practitionerTHERAPIESInternal Family Systems (IFS)Compassionate Inquiry (CI)Acest episod este produs și distribuit cu susținerea E.ON Energie România. Episodul este creat în colaborare cu Compassionate Inquiry România, parte din inițiativa ReConnect 2025, un eveniment dedicat tratării și prevenirii adicțiilor. (00:00) Introduction(04:09) Mark's Journey: Addict → Scientist → Therapist(09:50) The Dopamine Myth Debunked(12:52) Addictive Learning vs. Healthy Learning(16:05) Why Some Get Addicted & Others Don't(19:59) Connection: The Opposite of Addiction(23:50) Genes vs. Environment in Addiction(29:20) The Most Important Thing Parents Can Do(36:50) How to Talk to Kids About Drugs(39:55) Different Pain = Different Addictions(46:53) The Neuroscience of Alcohol(51:21) Why Addiction Isn't a Disease(56:27) Different Paths to Recovery from Addiction(01:03:03) Internal Family Systems Therapy Explained(01:05:12) The Three Parts: Critic, Firefighter, Exile(01:07:52) Self-Compassion as the Engine of Healing(01:14:25) Processing Trauma Later in Life(01:17:50) Mark's Daily Healing Practices(01:21:33) The Science of Breaking Bad Habits(01:28:54) Can You Heal Without Self-Love?(01:34:59) Three Questions to Transform Addiction Treatment

Are you doing all the right things—clean eating, daily workouts, supplements—yet feeling tired, inflamed, or stuck in a midlife plateau? On today's deep-dive episode of The Coach Debbie Potts Show, we unravel the hidden biology behind slow metabolism, stubborn fat gain, chronic fatigue, and the loss of muscle as we age. Coach Debbie Potts—FDN-P, FNTP, NASM-CPT, and certified PNOĒ Metabolic Analyst—guides you through the interconnected systems that determine how you age, burn fat, build muscle, and generate energy from the inside out. This is not your typical "eat less, move more" conversation. This is FutureYou Biology—the science of rebuilding metabolism, rewiring resilience, and restoring cellular safety so you can thrive, not struggle, in midlife. In This Episode, You'll Learn: PNOĒ Metabolic Testing — Your Real-Time Metabolic Blueprint How RER, VO₂ Max, FatMax, and ventilatory efficiency reveal whether your metabolism is stuck in sugar-burning mode or capable of efficient, flexible fat oxidation. AMPK — The Fat-Burning, Repair, and Longevity Switch Why Zone 2, fasting windows, cold exposure, and specific nutrients activate AMPK to improve mitochondria, reduce inflammation, and enhance metabolic flexibility. The Cell Danger Response (CDR) — When Mitochondria Hit the Brakes Based on Dr. Robert Naviaux's research, we explore why chronic stress, toxins, infections, or trauma push your mitochondria into "protection mode"—slowing metabolism, lowering energy, and blocking fat loss. The Vagus Nerve — The Hidden Root of Weight Loss Resistance If your nervous system doesn't feel safe, your metabolism won't unlock. Learn how vagal tone affects digestion, hormones, inflammation, and fat-burning—and how to train the vagus for better metabolic outcomes. mTOR + Protein After 40 — How to Rebuild Muscle & Strength Why women and men after 40 need higher protein, targeted leucine, and heavy strength training to overcome anabolic resistance and maintain metabolic rate and longevity. Cortisol, Hormones & Aging The stress-metabolism connection: how elevated cortisol suppresses thyroid function, blocks fat burning, and accelerates aging—and how to fix the rhythm. The FutureYou™ Formula How AMPK, mTOR, the vagus nerve, and mitochondrial health integrate into a personalized, test-not-guess blueprint for metabolic harmony. Featured Framework: FutureYou™ Meal Method Protein-forward, leucine-optimized meals to turn on muscle protein synthesis, maintain metabolic health, and improve fat-burning—especially for midlife women and men. "Protein is the ignition switch for metabolism. Leucine is the spark plug." — Coach Debbie Takeaway Aging well isn't luck—it's strategy. When you retrain metabolism, restore cellular safety, and rebuild vagal resilience, your body becomes capable of fat-burning, muscle building, and long-lasting energy again. It's time to rewrite your midlife biology and create your FutureYou. Work With Coach Debbie Ready to stop guessing and start testing? Book your PNOĒ Metabolic Test or schedule a discovery call at:

What if uncertainty isn't something to fear… but one of the greatest advantages you have as a leader? In this episode of The BrainVault Podcast, Larry Olsen sits down with Scott Stirrett — best-selling author of The Uncertainty Advantage, founder of Venture for Canada, and a rising force in modern leadership. Scott's journey from leaving Goldman Sachs at 22 to building a national organization reveals one powerful truth: leadership isn't about having all the answers. It's about how you navigate the unknown. Together, Larry and Scott explore how clarity, self-compassion, and purpose can transform the way you lead yourself and others. You'll learn why focusing on the journey builds more momentum than fixating on outcomes, how to quiet the pull of comparison, and why your “true north” becomes the anchor that guides every decision you make. Scott shares the mindset that helped him impact thousands of lives, and Larry brings forward insights that remind us: growth isn't about perfection. It's about who you bring to the moment. If you're ready to lead with more confidence, purpose, and vision—this conversation opens the door. Press play and step into a new perspective on the power of uncertainty.

Synopsis: This episode is proudly sponsored by Quartzy. In this far-reaching conversation, Rahul Chaturvedi speaks with John Lepore, CEO & President of ProFound Therapeutics and CEO-Partner at Flagship Pioneering, tracing a career shaped by a deep commitment to understanding the causal machinery of human disease. John shares how a Harvard-trained physician-scientist evolved into a biotech leader building one of the industry's most ambitious platform companies. Reflecting on 17 years at GSK — from academic cardiologist to running global research — John describes the moment he realized traditional target discovery had reached its limits. That insight propelled him into Flagship's venture-creation ecosystem and ultimately into leading ProFound Therapeutics, where the team is uncovering tens of thousands of previously unknown human proteins that could fundamentally reshape drug discovery and unlock true first-in-class opportunities. John also offers a candid look at today's biotech leadership realities: navigating capital-tight markets, fostering high-trust pharma partnerships, making disciplined early kill decisions, and using AI to extract causal insights from vast proteomic datasets. Together, he and Rahul explore why the expanded human proteome may be medicine's next great frontier — and what it takes, scientifically and psychologically, to lead a company bold enough to pursue it. Biography: John Lepore, M.D., is CEO and President of ProFound Therapeutics and CEO-Partner at Flagship Pioneering, where he is leading a new era of drug discovery by harnessing the expanded proteome to build a pipeline of first-in-class medicines. A physician-scientist and accomplished pharma executive, he joined ProFound following a 17-year career at GSK, where he was most recently SVP, Head of Research, leading a 2,500+ person global team and driving a renewed focus on immunology and human genetics across target discovery and validation, modality platforms, drug discovery, and clinical translation. He also chaired GSK's Research Review and Investment Board, guiding capital allocation and R&D strategy. Under his leadership, GSK advanced 15 Phase 1 programs with first- or best-in-class potential and executed $1B+ in strategic R&D deals. Before joining the biopharma industry, Dr. Lepore was a faculty cardiologist and research investigator at the University of Pennsylvania, where his lab investigated the transcription regulation of cardiovascular development. He currently serves on the boards of ProFound, KSQ Therapeutics, and the Innovation Growth Board of Mass General Brigham. Dr. Lepore received his B.S. in Biology from the University of Scranton and his M.D. from Harvard Medical School, after which he completed his residency and post-doctoral training at Massachusetts General Hospital and the Harvard School of Public Health.

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A team of scientists is trying to jumpstart a global conservation movement, on par with efforts to save the rainforests or protect the oceans. But it might be even more ambitious because the target of their quest is invisible, everywhere, and mostly something we try to hand-sanitize away: microbes.So how do you conserve something that is everywhere and in everything? And why do microbes need protecting to begin with? Host Flora Lichtman digs into it with microbial ecologist Jack Gilbert, who is leading this charge. They chat about the thinking behind microbe conservation plans, and why some scientists are hesitant to jump onboard.Guest: Dr. Jack Gilbert is a microbial ecologist at the Scripps Institution of Oceanography and co-chair of the International Union for Conservation of Nature's Species Survival Commission's Microbial Conservation Specialist Group. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

In this episode, we dive into the world of custom duck calls with Farrel Charpentier, a maker whose roots run deep in South Louisiana. Hear how he transitioned from offshore work to call making, why he chose the Arkansas-style call, and the challenges of perfecting sound and design. Plus, insights into Reelfoot Lake's unique call maker gathering and the camaraderie that defines this craft.https://www.facebook.com/farrel.charpentier/Listen now: www.ducks.org/DUPodcastSend feedback: DUPodcast@ducks.orgSPONSORS:Purina Pro Plan: The official performance dog food of Ducks UnlimitedWhether you're a seasoned hunter or just getting started, this episode is packed with valuable insights into the world of waterfowl hunting and conservation.Bird Dog Whiskey and Cocktails:Whether you're winding down with your best friend, or celebrating with your favorite crew, Bird Dog brings award-winning flavor to every moment. Enjoy responsibly.

Many high-achieving people look successful on the outside while part of them remains frozen in childhood survival patterns. Through the Biology of Trauma® lens, I share how trauma disrupts the natural flow and movement of life—and the healing roadmap that takes us from stuck to truly alive. If we've ever wondered why we can reach every external goal and still feel disconnected from our own life, this episode explains why. I share Elena's story, a 45-year-old Chief Operating Officer whose autoimmune diagnosis revealed what her body had been holding for decades. When her thirteen-year-old daughter had thoughts of suicide—and felt she couldn't talk to her mom—Elena finally understood: a part of her had been frozen since before she could walk. We'll explore how nervous system dysregulation shows up as professional success masking emotional unavailability. We'll see how trauma stops our natural movement through life—and discover the six-step roadmap from survival to authenticity, belonging, and flow. In this episode you'll learn: [00:00] Why successful people can still be frozen in survival patterns from childhood [02:15] How Elena's birth trauma created a freeze response before she could walk [06:40] The moment her daughter's crisis revealed decades of emotional unavailability [09:10] Trauma defined: the biggest disruptor of movement in our life [12:45] Why everything inside us is movement—and what happens when trauma stops it [16:05] The healing destination: authenticity, belonging, and flow as what it means to be alive [19:50] Why state shifts matter more than neuroplasticity on your healing journey [24:05] How neuroplasticity wires in whatever state you're in—including overwhelm [26:30] The six-step roadmap: from "I am alive" to connection with others [28:15] How Elena broke the generational cycle with her daughters Main Takeaways: Trauma Is the Biggest Disruptor of Movement: Trauma isn't just an event—it's the shock that stops us. It disrupts movement at every level: physical, emotional, relational, and through our life stages. Successful and Frozen Can Coexist: High achievement doesn't mean our nervous system is regulated. Elena built an impressive career while part of her remained that terrified little girl, hiding and staying still to survive. State Shifts Come Before Neuroplasticity: Whatever state we're in is what neuroplasticity wires in. If we're frequently in stress and overwhelm, our brain builds pathways that make that pattern automatic. We must shift our state first. The Destination Is Authenticity, Belonging, and Flow: These three elements define what it means to be truly alive—free to be ourselves, grounded in connection, and moving with ease through life. You Can't Skip the Sequence: The roadmap follows a specific order: recognizing we're alive, choosing to live, shifting our state, being here, wanting to be here, deserving to be here, and finally connecting with others. Each step prepares us for the next. Healing Breaks Generational Patterns: When Elena addressed her frozen patterns, her daughters noticed changes they never expected. The "resting bitch face" disappeared. Presence replaced absence. Notable Quotes: "Trauma becomes the biggest disruptor of movement in our life." "I can still see myself as a little girl, hiding with my dolls, quiet, still and absolutely terrified." "Whatever state we are in is what neuroplasticity wires in." "Being in calm alive can actually become a habit. Imagine that." "Your body's decision to freeze wasn't a failure—it was survival. But you don't have to stay frozen." "My 12-year-old girl didn't realize that I had grown up and that I am alive—which means that she did it. She made it. We're alive." Episode Takeaway: Frozen doesn't mean broken. Elena's story reveals what happens when trauma stops our natural movement through life—not just physical movement, but emotional presence, relational connection, and our ability to truly arrive in the life we've built. Her freeze response began at birth, reinforced through childhood, and showed up decades later as professional success masking emotional unavailability. Her daughters felt it. Her body felt it. Her autoimmune diagnosis confirmed it. The healing roadmap offers a way forward. First, we help that frozen part recognize we're alive—that survival happened. Then we consciously choose to live, rather than simply existing because we had no choice. We learn to shift our state into calm and aliveness, practicing until it becomes our new default. And finally, we move through the deeper work: being here, wanting to be here, deserving to be here, and opening to genuine connection with others. Neuroplasticity works for or against us depending on our state. If overwhelm has become our habit, our brain has built pathways that take us there automatically. But when we build the habit of calm aliveness first, neuroplasticity starts working in our favor. The destination isn't perfection—it's authenticity, belonging, and flow. Movement is possible. Coming home to ourselves is possible. Resources/Guides: The Biology of Trauma book - Available now everywhere books are sold. Get your copy Foundational Journey - If you are ready to create your inner safety and shift your nervous system, join me and my team for this 6 week journey of practical somatic and mind-body inner child practices. Lay your foundation to do the deeper work safely and is the pre-requisite for becoming a Biology of Trauma® professional. Related Episodes: Episode 9: What is One Thing the Freeze Response Needs for Healing? (Part 2) with Dr. Arielle Schwartz Episode 87: Stress & Freeze Response: How to Achieve & Sustain High Performance with Olympian Louise Tjernqvist Episode 142: Why Stress Isn't Trauma: How to Spot Overwhelm and Start Healing Your Nervous System with Dr. Aimie Apigian   Your host: Dr. Aimie Apigian, double board-certified physician (Preventive/Addiction Medicine) with master's degrees in biochemistry and public health, and author of the national bestselling book "The Biology of Trauma" (foreword by Gabor Maté) that transforms our understanding of how the body experiences and holds trauma. After foster-adopting a child during medical school sparked her journey, she desperately sought for answers that would only continue as she developed chronic health issues. Through her practitioner training, podcast, YouTube channel, and international speaking, she bridges functional medicine, attachment and trauma therapy, facilitating accelerated repair of trauma's impact on the mind, body and biology. Disclaimer: By listening to this podcast, you agree not to use this podcast as medical, psychological, or mental health advice to treat any medical or psychological condition in yourself or others. This podcast is for informational and educational purposes only and does not constitute professional advice, diagnosis, or treatment. Always consult your own physician, therapist, psychiatrist, or other qualified health provider regarding any physical or mental health issues you may be experiencing.

Your brain and body have been programmed for millions of years to work against your success.In this episode, I'm breaking down the 4 ways to rewire yourself for success.

Send us a textMethods & challenges of establishing causal relationships in health research, emphasizing epidemiology, randomized trials, and genetic approaches.Topics:Epidemiology: Studies disease influences using observational designs like case-control and prospective cohorts, plus trials, to identify patterns and test hypotheses.Hierarchy of evidence critique: Rejects rigid pyramids favoring RCTs, as all studies can be biased; advocates triangulation integrating varied data types for robust conclusions.RCT strengths & weaknesses: Randomization balances confounders, but issues like poor blinding, attrition, or subversion can undermine results; large samples may yield spurious precision if biased.Confounding & reverse causation: Examples include yellow fingers and lung cancer (both from smoking) or early atherosclerosis inflating CRP-disease links; hard to fully control statistically.Nutrition epidemiology: Observational studies often overstate benefits (e.g., vitamin E for heart disease), leading to failed trials; incentives favor new findings over revisiting errors.Mendelian randomization: Uses genetic variants as proxies for exposures (e.g., ALDH2 for alcohol metabolism) to mimic randomization; reveals no heart benefits from alcohol, unlike observational data.Negative controls: Tests implausible outcomes (e.g., smoking and murder) or exposures (e.g., paternal smoking in pregnancy) to check for confounding artifacts.Evidence triangulation: Combines diverse studies with different biases (e.g., cross-cultural comparisons) for causality; applied to dismiss HDL-raising drugs despite initial promise.Practical Takeaways:Scrutinize health claims by checking for negative controls or variety in evidence sources to avoid mistaking correlation for causation.For personal decisions like alcohol intake, consider genetic studies showing risks at all levels, and aim for moderation or abstinence based on overall evidence.When evaluating supplements or diets, prioritize trials over observational data, and question media hype that ignores confounding factors.About the guest: Dr. George Davey Smith, MD, DSc is a professor of clinical epidemiology at the University of Bristol and director of the MRC Integrative Epidemiology Unit.*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. MINDMATTER gets you 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

So many midlife women describe themselves as stressed, but what if what we're calling “stress” is actually something deeper happening inside the body? In this powerful conversation, Heather sits down with Dr. Aimie Apigian, physician, speaker, and author of The Biology of Trauma, to unpack the difference between everyday stress and stored trauma that shows up as overwhelm, exhaustion, irritability, or feeling “stuck.” Together, they explore why midlife is often the moment unresolved patterns surface, how the nervous system drives our physical and emotional responses, and why pushing harder, at work, at home, or even in the gym, can actually reinforce a survival state. Dr. Aimie shares how to know the difference of recognizing tools for healing rather than triggers for dysregulation, and she offers the first steps to reset your system, build true resilience, and reconnect with the energy and clarity you've been missing. If you've been living in go-mode for so long it feels normal, this episode will help you understand your body, reclaim your power, and finally begin your reset. Find Dr. Aimie here: https://www.biologyoftrauma.com/Grab The Biology of Trauma here Thanks for listening whether you were folding laundry, going for a walk or whatever other multi-tasking you were getting after. I am having so much fun sharing and connecting with you, badass! Be sure to hit subscribe and get notified of the next impactful episode of The Badass Reset Club which drops every other Tuesday. Curious about how Symmetry can help you boost performance, get out of pain and fix your posture? Book a free call! https://www.heatheryanceyfitness.com/Symmetry Be a founding member of The Menopause Strength Society and join today! https://www.heatheryanceyfitness.com/community Follow me on Instagram https://www.instagram.com/coachheatheryancey/ Ladies, join our private facebook for menopause support and more! https://www.facebook.com/groups/badassresetclub If you want to watch the podcast to see if I actually did something with my hair, find us here: https://www.youtube.com/@heatheryanceyfitness Ready to feel better with the Age Like a Badass Menopause course? Grab it and start taking action today! https://www.heatheryanceyfitness.com/offers/BEHgRUEg Wanna get STRONG? Grab my free 4 week Strength Training program! In 1 month, you will feel stronger, more confident and badass again! https://www.heatheryanceyfitness.com/opt-in Thorne Collagen discount - https://www.thorne.com/u/Yancey Platinum Red Light Therapy - https://snwbl.io/platinumled-therapy-lights/ZEZAC8005

With your co-hostesses: Lyschel Burket from HopeRedefined.org Bonny Burns from StrongWives.com  Temporary Hostess Amy Matters of Matterswellness.com Support HFW through a donation   Listen now: Welcome to another episode of Hope For Wives, today we are so excited to introduce you to another extended guest host, Amy Matters! This is Amy's first time with us and while some people chase the spotlight, as a functional health practitioner, she is guiding others toward wholeness from the inside out. Thank you for being with us, Amy!  We are diving into Amy's strengths in this episode as we discuss the biology of betrayal trauma. Many think that betrayal trauma is only a mental and emotional experience. It's more than that. Betrayal trauma causes physical changes, as well. We Will be Discussing: What's actually happening inside the body when someone experiences betrayal trauma? Why do symptoms like brain fog, anxiety, and exhaustion show up after betrayal? How does betrayal impact hormones and the stress response system? Resources mentioned in this show: Amy Matters Holistic Functional Health Practitioner Website

Matthew Alper is a passionate researcher and author best known for his provocative work The 'God' Part of the Brain, in which he explores the idea that spirituality and belief in a higher power may be rooted not in external divinity, but in the very wiring of the human brain. Drawing on philosophy, psychology, anthropology, and evolutionary biology, Alper argues that our longing for transcendence, our tendency toward religious and mystical experiences, and even our existential fear of mortality are biologically and neurologically encoded responses rather than purely cultural constructs. His work invites readers to reconsider traditional spiritual narratives through a scientific lens — challenging assumptions about divinity and offering a worldview in which God-concepts emerge through human cognition and evolution. Whether embraced or debated, Alper's perspective remains a bold attempt to reconcile science, spirituality, and the human experience.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-x-zone-radio-tv-show--1078348/support.Please note that all XZBN radio and/or television shows are Copyright © REL-MAR McConnell Meda Company, Niagara, Ontario, Canada – www.rel-mar.com. For more Episodes of this show and all shows produced, broadcasted and syndicated from REL-MAR McConell Media Company and The 'X' Zone Broadcast Network and the 'X' Zone TV Channell, visit www.xzbn.net. For programming, distribution, and syndication inquiries, email programming@xzbn.net.We are proud to announce the we have launched TWATNews.com, launched in August 2025.TWATNews.com is an independent online news platform dedicated to uncovering the truth about Donald Trump and his ongoing influence in politics, business, and society. Unlike mainstream outlets that often sanitize, soften, or ignore stories that challenge Trump and his allies, TWATNews digs deeper to deliver hard-hitting articles, investigative features, and sharp commentary that mainstream media won't touch.These are stories and articles that you will not read anywhere else.Our mission is simple: to expose corruption, lies, and authoritarian tendencies while giving voice to the perspectives and evidence that are often marginalized or buried by corporate-controlled media

In this episode of Talk Nerdy, Cara is joined by science writer and longtime independent journalist, Melanie D. G. Kaplan. They discuss Melanie's newest book, Lab Dog: A Beagle and His Human Investigate the Surprising World of Animal Research. Follow Melanie: @melaniedgkaplan

Discover the latest science behind fasting and innovative fasting alternatives in this episode with Dr. Chris Rhodes, nutritional biochemist. Learn about the anti-inflammatory and longevity benefits of a 36-hour fast, and how Mimio, a fasting supplement, can help you access fasting's advantages without skipping meals. With special insights on women's health—including hormones, muscle preservation, and metabolic changes—this is essential listening for anyone interested in optimizing wellness, especially women navigating midlife.Curious to try Mimio for yourself? Visit https://drstephanieestima.com/mimio and use code ESTIMA for 20% off. Episode Overview (timestamps are approximate):(0:00) Intro/Teaser(4:00) The Biology of Fasting: What's Actually Happening(12:00) Fasting Timelines: 16:8 vs 24hr vs 36hr(16:00) The 36-Hour Metabolic Signature(21:00) NAD, Estrogen, and Women in Midlife(26:00) Cortisol, HPA Axis, and Female Sensitivity(30:00) Thyroid Suppression During Fasting(34:00) Muscle and Bone Preservation Strategies(43:00) The Four Fasting-Mimetic Molecules(54:00) Fasting Benefits Without Fasting(1:03:00) Clinical Study Results: 2.5 Years Younger(1:07:00) Dosing and Best Practices(1:12:00) BONUS: After-Party with Dr. StephanieResources mentioned in this episode can be found at https://drstephanieestima.com/podcasts/ep445/We couldn't do it without our sponsors:BON CHARGE - Achieve glowing skin, gain more energy, and uplevel your recovery practice with a suite of red light products. Get 15% off at https://boncharge.com/better with code BETTER.TROSCRIPTIONS - There's a completely new way to optimize your health. Give it a try at https://troscriptions.com/BETTER or enter BETTER at checkout for 10% off your first order.BIOPTIMIZERS - Your digestion can take a hit in midlife, but you don't have to suffer. Learn how enzymes can help at https://bioptimizers.com/better and use code BETTER to get 10% off your order.MASA - MASA's chips contain just three ingredients: organic nixtamalized corn, sea salt, and 100% grass-fed beef tallow. That's it. Ready to give MASA (or Vandy) a try? Use code BETTER for 25% off your first order at https://masachips.com/BETTERLMNT - Rehydrate with the perfect mix of sodium, potassium, and magnesium. Get a free sample pack at https://drinklmnt.com/drestima. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

In this transformative episode, I sit down with my own teacher and mentor, Dr. Karen Parker, to explore the fascinating world of Quantum Human Design and how our stories literally shape our biology. Dr. Parker is a pioneer who studied with the founder of traditional Human Design and has taken the system to its next evolution—helping people not just understand who they're not, but consciously create who they want to become.  What You'll Discover  Understanding Quantum Human Design  The difference between traditional Human Design and Quantum Human Design  How Human Design synthesizes Eastern and Western astrology, the Chinese I Ching, Hindu chakra system, and Judaic Kabbalah  Why getting back into your body is essential for authentic decision-making  The evolution from learning "who you're not" to consciously creating "who you choose to become"  The Biology of Our Stories  How victim-based narratives actually lower immune response (IgA levels)  The physiological changes that occur when you reframe your story  Why optimists live longer and have longer telomeres  The connection between storytelling and post-traumatic growth  Moving Beyond Survival  Why defining ourselves as "survivors" keeps us stuck at a minimal baseline  The danger of stopping your story at the cliffhanger  How to move from surviving to thriving through the redemption arc  The Stage 3 trap: how repeating our betrayal story keeps us stuck  The Story Lab Process  A creative, fun approach to rewriting your narrative (yes, it can be enjoyable!)  Using creative writing to bypass logic and reasoning patterns  Why taking your story "out of time" creates powerful shifts  Real-life example: How one woman transformed from victim to empowered protector  Key Takeaways  Your story creates your identity, and your identity calls in experiences that validate it. Breaking this cycle requires conscious narrative reframing.  Healing doesn't have to be a crisis. The Story Lab process proves that transformation can actually be creative, playful, and fun.  Check in with your body. After sharing your betrayal story, does your body feel light, open, and expansive? Or heavy and contracted? Your body knows the truth.  The power of the redemption arc. Your story doesn't end at the betrayal—that's just the catalyst. The real story is what happens next and who you become.  Powerful Exercise to Try  Draw a horizontal line across a piece of paper. The left represents your birth, the right represents where you are now. Mark all the significant experiences in your life along this timeline. Then ask yourself: "Did I stop my story at the cliffhanger, or have I defined myself by what happened next?"  If you're still hanging at the cliffhanger, you deserve better than that.  About Dr. Karen Parker  Dr. Karen Parker holds a PhD in transpersonal psychology and is the creator of Quantum Human Design. She studied directly with the founder of traditional Human Design and spent three years in a Sound Lab testing the frequency of vocabulary to create an entirely new system that helps people consciously write their sovereign story. She's also the author of multiple books, including Quantum Wellness, which walks readers through the Story Lab process.  Connect with Dr. Karen Parker  Website: QuantumHumanDesign.com  Instagram & Facebook: @DrKarenParker22  Book: Quantum Wellness (available at major online retailers)  Stay in Touch  The PBT Institute: https://thepbtinstitute.com   My Personal Connection  As a 4/6 Manifesting Generator (Time Bender) myself, studying with Dr. Karen was life-changing. Learning about the triphasic life cycle of the 4/6 profile helped me understand why my life crashed and burned at exactly age 50—and why that was actually the beginning of my true purpose work. The concept of "finding shortcuts" as a Manifesting Generator perfectly explains why the five stages of Post Betrayal Transformation showed up in my research—it was THE shortcut to healing! 

Chaos, crisis and collapse can feel like the new normal - but what if they're actually signs that an old, unsustainable civilisation is breaking down so a new one can emerge? In this conversation, Angela sits down with stem cell biologist and author Dr Bruce Lipton to explore why we are not victims of our genes or our past, but powerful creators whose subconscious programming shapes our health, relationships and reality. They get into how early childhood conditioning runs most of our behaviour, why stress and belief can be more influential than genetics when it comes to disease, and how epigenetics and energy psychology show we can rewrite our internal code. Bruce shares practical tools - from self-hypnosis to “super-learning” postures - to help you change limiting programmes, raise your vibration and experience more of what he calls “heaven on earth” now. WHAT YOU'LL LEARN • How early brain states imprint family and cultural patterns for life • The practical difference between conscious choice and subconscious autopilot • What epigenetics reveals about belief, perception and gene expression • How chronic stress suppresses immunity, repair and clear thinking • Two common limiting beliefs and where they come from • Simple daily tools to reprogramme the subconscious (including self-hypnosis and repetition) • How energy psychology, super-learning postures and vibration can support creating a life that feels aligned and meaningful Timestamps0:00:00 Intro: Why The World Feels Out of Control0:03:05 The Subconscious Mind: The Hidden Programs Running 95% of Your Life0:06:59 Why Do We Self-Sabotage? Understanding Limiting Beliefs0:09:20 Do Genes Really Cause Disease? The Truth About Cancer and Epigenetics0:13:05 Why You Keep Repeating Old Patterns (Even When You Don't Want To)0:23:21 Can You Rewrite Your Subconscious Mind? (Self-Hypnosis, Repetition, Energy Psychology)0:29:05 Why Most People Don't Love Themselves (And How to Change It)0:33:17 How Chronic Stress Shuts Down Healing & Intelligence0:41:47 Angela's Healing, Motherhood and the Decision to Live1:00:31 How Vibration and Attraction Shape Your Reality1:04:29 What Is the Soul? The Science of Why You Don't Die1:08:10 Is Heaven Already Here? VALUABLE RESOURCES A BIG thank you to our sponsors who make the show possible:• Supercharge your energy and upgrade your mitochondria with Mitopure -

In this episode of Somnilopod, host Jay McGuire breaks down the real science behind snoring in a calm, accessible way that helps listeners understand what's actually happening inside the airway during sleep. Jay explains why snoring occurs, how airflow becomes restricted, and why factors like aging, anatomy, sleep position, stress, and lifestyle habits can make nighttime breathing noisier than we'd like. He also covers the important connection between snoring, sleep quality, and the nervous system—highlighting how micro-awakenings, stress, and poor sleep hygiene can create a cycle that affects overall wellness and energy levels. Listeners will learn the difference between ordinary snoring and the warning signs of obstructive sleep apnea, plus simple, practical steps to improve airflow, relax the body, and support healthier breathing at night. Whether you're a lifelong snorer, sleep next to one, or are simply curious about the biology behind the "bed-shaking sound," this episode offers clear explanations and compassionate guidance.

In this Thanksgiving replay, we revisit our conversation with Paul Shapiro, co-founder and CEO of Better Meat Co, who's pioneering the use of mycelium-based proteins as a sustainable alternative to animal meat. Paul shares his remarkable journey from starting an animal welfare organization in high school to becoming a biotech entrepreneur. He explains how fungi fermentation creates protein-rich, meat-like textures in less than 24 hours without the environmental toll of traditional agriculture. The episode explores the science behind mycoprotein, the challenges facing the alternative protein industry, the need for government investment in biomanufacturing, and why fungi may be the key to feeding both Earth and future space travelers. Paul also discusses Better Meat Co's recent $31 million Series A funding and their mission to make sustainable protein accessible at scale.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Chapters:(00:00:00) - Could Fungi Replace Factory Farms Forever?(00:01:00) - Welcome: TEDx MIT, Planetary Action & What's Growing(00:03:00) - Intelligence Beyond Brains: Reflecting on Michael Levin(00:06:00) - Thanksgiving Special: Gratitude for the Biotech Community(00:10:00) - Meet Paul Shapiro: From Activist to Mycoprotein Pioneer(00:13:00) - Origin Story: Fighting for Animals Led to Building Better Meat(00:19:00) - Alt Protein 2.0: What's Changed Since the 2018 Hype Cycle(00:24:00) - The Subsidy Problem: Why Meat Gets Billions & Clean Protein Gets Nothing(00:31:00) - Mycoprotein 101: Why Fungi Beat Plants for Meat Texture(00:38:00) - Engineering Neurospora: 24-Hour Fermentation at Scale(00:43:00) - Designing Super Strains: Breeding Microbes for Performance(00:48:00) - Creating Craveable Protein: Flavor Science & B2B Strategy(00:51:00) - Space Food Systems: Why Astronauts Will Farm Fungi, Not Cows(00:56:00) - Biomanufacturing Infrastructure: The $31M Series A Story(01:00:00) - Industry Reality Check: Cultivated Meat's Path Forward(01:03:00) - Beyond Food: Mycoremediation & Paul's Business for Good Podcast(01:05:00) - Closing Thoughts: Solving the Flavor Challenge & Scaling ImpactLinks and Resources:Better Meat Co.Time's Best Inventions of 2025Paul ShapiroClean Meat Novel by Paul ShapiroHomeworld Collective Cascade Bio33. Purple Reign, A Purple Tomato with a Genetic Twist, Nathan Pumplin of Norfolk Healthy Produce83. Bottoms Up: Microbe Mixology with Zbiotics' Zack Abbott156. When Matter Makes Decisions: Michael Levin on the Intelligence of FormJohn Werner - TEDxThe Mountain in the Sea by Ray Nayler⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Topics Covered: developmental biology, morphology, morphospace, planarians, electroceuticals, bioelectricity, tissue regeneration, biomedical applications,  Have a question or comment? Message us here:Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Email: groweverything@messaginglab.com

It's our 100th episode! I celebrate this milestone with Karen Bradley, NP, discussing the biggest wins, most common questions, and key themes from nearly two years of podcasting about women's sexual health and menopause.We dive into the FDA's recent decision to remove the boxed warning from vaginal estrogen a huge victory for women's health advocacy. This warning has prevented countless women from getting treatment for painful sex, recurrent UTIs, and other symptoms of genitourinary syndrome of menopause. I share a powerful story of a patient with breast cancer history who was denied hormone therapy by her oncology team, only to have them completely reverse course once the boxed warning was removed.The conversation covers the most frequently asked questions from listeners: Is it perimenopause or just stress? (It's both.) Why is my libido gone? (Biology, psychology, and life circumstances all play a role.) Why do I keep getting UTIs after sex? (Often it's vestibulodynia or changes in the vaginal microbiome from estrogen deficiency.) How do I talk to my partner about sex? (Communication is key, and sometimes you need a sex therapist to help.)We also discuss the reality of midlife weight gain, the role of GLP-1 medications like Wegovy and Zepbound, and why building muscle matters more than endless cardio. This episode is a celebration of how far we've come and a reminder that you don't have to suffer through menopause.Highlights:The FDA removed the boxed warning from vaginal estrogen—what this means for access to careThe biology behind midlife low libido and why it's not "all in your head"Why recurrent UTIs after sex might actually be vestibulodynia or vaginal microbiome changes.How to talk to your partner about sex when you've never had those conversationsThe truth about midlife weight gain and what hormones can and can't doGLP-1 medications: FDA approvals for weight loss, cardiovascular protection, MASH, and sleep apneaThank you for being here for 100 episodes. Honestly, there have been times I've wanted to stop, but then I get a DM from someone saying they heard something on the podcast that changed their care, or a patient tells me they finally found answers here. That's what keeps me going.The biggest way you can help me keep doing this work is simple: share this show with someone who needs it and hit subscribe. When you share an episode with a friend who's struggling, a family member who's been dismissed by doctors, or post about it on social media, you're helping me reach more women who deserve better care.Thank you for listening, for learning, and for advocating alongside me. Here's to the next 100.Get in Touch with Me: WebsiteInstagramYoutubeSubstack

Sarah is trying to talk Susie into loving winter sports, and it ain't working. In fact, she's decided Shaun White is on our list of people we have bad vibes about. We hear why Sarah thinks she'd be great at ice skating. We learn why breakfast foods are becoming more expensive, Florida is out of the orange juice biz, and Susie doesn't know what she's going to eat now. We find out why China is causing a bizarre boom in saxophone players, and Sarah has a theory about it. We discuss sports betting, why it's a problem, and how apparently you can be a "professional slot machine player." Plus, a woman found out she has the blood of a man, and we are baffled about how that works.00:00 - Sarah's Winter Sports Push and Shaun White'sBad Vibes09:46 - Breathe Cleaner Air with Air Doctor Air Purifiers12:01 - Why Orange Juice & Breakfast Staples Are Becoming a Luxury20:25 - Wrap Yourself in Luxury with Cozy Earth Bedding & Pajamas21:52 - The Shift to Struggle Meals as Breakfast Becomes Pricier27:00 - The Bizarre Boom of Saxophone Players in China33:57 - Share Cherished Memories with Aura Digital Photo Frames36:20 - ChatGPT Wins Lottery & The Dark Side of Sports Betting53:08 - The Incredible Case of a Woman with Male Blood Cells01:00:18 - Final Thoughts, Listener Thanks & Holiday WishesBrain Candy Podcast Website - https://thebraincandypodcast.com/Brain Candy Podcast Book Recommendations - https://thebraincandypodcast.com/books/Brain Candy Podcast Merchandise - https://thebraincandypodcast.com/candy-store/Brain Candy Podcast Candy Club - https://thebraincandypodcast.com/product/candy-club/Brain Candy Podcast Sponsor Codes - https://thebraincandypodcast.com/support-us/Brain Candy Podcast Social Media & Platforms:Brain Candy Podcast LIVE Interactive Trivia Nights - https://www.youtube.com/@BrainCandyPodcast/streamsBrain Candy Podcast Instagram: https://www.instagram.com/braincandypodcastHost Susie Meister Instagram: https://www.instagram.com/susiemeisterHost Sarah Rice Instagram: https://www.instagram.com/imsarahriceBrain Candy Podcast on X: https://www.x.com/braincandypodBrain Candy Podcast Patreon: https://www.patreon.com/braincandy (JOIN FREE - TONS OF REALITY TV CONTENT)Brain Candy Podcast Sponsors, partnerships, & Products that we love:Visit https://auraframes.com and get $45 off Aura's best-selling Carver Mat frames - named #1 by Wirecutter - by using promo code BRAINCANDY at checkout.Head to https://airdoctorpro.com and use promo code CANDY to get UP TO $300 off today! Stack my code BRAINCANDY on top of their sitewide sale at https://cozyearth.com — giving you up to 40% off in savings. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This Thanksgiving, we're thankful for wetlands, waterfowl, and YOU—our Ducks Unlimited family. Join us for a festive episode featuring gear recommendations, lively debates, and cherished holiday memories. Together, we'll celebrate the traditions that make hunting and conservation so special. Happy Thanksgiving from all of us at DU!DUCKS UNLIMITED GIFT GUIDEListen now: www.ducks.org/DUPodcastSend feedback: DUPodcast@ducks.orgSPONSORS:Purina Pro Plan: The official performance dog food of Ducks UnlimitedWhether you're a seasoned hunter or just getting started, this episode is packed with valuable insights into the world of waterfowl hunting and conservation.Bird Dog Whiskey and Cocktails:Whether you're winding down with your best friend, or celebrating with your favorite crew, Bird Dog brings award-winning flavor to every moment. Enjoy responsibly.

Send us a textIntegration of brain metabolism with neural signaling, highlighting how core metabolites regulate energy use and protect neurons.Topics Discussed:Brain energy efficiency: Brains are much more energy-efficient than computers for similar processing, relying on adaptive metabolic strategies evolved under energy scarcity.Metabolism vs. information processing: Core metabolites like glutamate bridge basic cellular energy production and neural signaling.Lactate as a signal: Produced during exercise, lactate diffuses from muscles to brain, modulating neuronal excitability and providing neuroprotection.BHB in ketosis: During fasting or ketogenic diets, beta-hydroxybutyrate displaces glucose as fuel, enhances antioxidant defenses, and activates protective potassium channels in neurons.Adenosine and sleep: Accumulates from ATP breakdown during wakefulness, triggering sleep and locally inhibiting overactive neural networks for energy conservation.Glial cells' role: Astrocytes and oligodendrocytes handle sophisticated metabolism, release signaling molecules like lactate, and modulate synapses, and influence diseases like Alzheimer's.Practical Takeaways:Regular exercise elevates lactate, which signals the brain to adapt metabolism and may enhance neuroprotection against stress.Intermittent fasting or ketogenic diets can induce ketosis with BHB, potentially boosting brain antioxidant defenses and preconditioning against metabolic stress.Prioritizing sleep helps clear adenosine buildup, restoring energy balance and supporting long-term neural health.About the guest: Dr. Luis Felipe Barros, MD, PhD is a Chilean neurobiologist and professor at the Universidad de Valparaíso, where he leads a lab studying brain metabolism from glucose transport to mitochondrial function.Related Episode:M&M 255 | Unlocking Energy: How Nutrition & Drugs Impact Your Mitochondria | Chris Masterjohn*Not medical advice.Support the showAffiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. Special sale Nov 10 - Dec 1: Lumen is half off ($599 → $299), and MINDMATTER gets another 15% off. AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, get $100 off for AquaTru Carafe, Classic and Under the Sink Units, and $300 off Freestanding models. Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) For all the ways you can support my efforts

What if the key to more effective leadership lies not in a new strategy, but in understanding your own biology? In this episode, Kevin speaks with Dr. Scott Hutcheson about an unconventional approach to leadership: biohacking. Dr. Hutcheson shares his behavioral leadership model, built around three biodynamic channels: warmth, competence, and gravitas. He identifies specific, observable behaviors within each channel that send powerful signals to teams, signals that either inspire connection and confidence or lead to disengagement. They also discuss how everyday actions like being punctual, actively listening, and managing workload effectively are more than simple good habits. These behaviors function as leadership signals that directly shape how teams perceive their leaders and, ultimately, how they perform. Scott's Story: Dr Scott Hutcheson, PhD, is the is the coauthor of Strategic Doing: Ten Skills for Agile Leadership and his new book, Biohacking Leadership: Leveraging the Biology of Behavior to Maximize Your Impact – the first in a three-book series on the biodynamics of leadership, teams, and organizations. He is a biosocial scientist and senior lecturer at Purdue University, where he studies leadership, teamwork, and organizational performance through the biology of behavior. After a Type 2 diabetes diagnosis, he turned to biohacking—using data and feedback loops to optimize health—and soon recognized that the same principles could transform leadership. With over 30 years of experience, Scott has advised the White House, Fortune 400 companies, startups, nonprofits, and communities worldwide. He has worked with more than 4,000 leaders across 147 countries. His TED Talk on the "Science of Prospection" has been viewed over 1.3 million times, and his Forbes column reaches millions of readers, ranking in the top 0.1% of contributors. This Episode is brought to you by... Flexible Leadership is every leader's guide to greater success in a world of increasing complexity and chaos.  Book Recommendations Biohacking Leadership: Leveraging the Biology of Behavior to Maximize Your Impact by Scott Hutcheson Atmosphere: A Love Story by Taylor Jenkins Reid Like this? Lessons from a Fortune Top 50 Leader with Mitch Daniels Executive Presence with Joel Garfinkle The 8 Strengths that Redefine Confidence with Lisa Sun Leave a Review If you liked this conversation, we'd be thrilled if you'd let others know by leaving a review on Apple Podcasts. Here's a quick guide for posting a review. Review on Apple: https://remarkablepodcast.com/itunes    Join Our Community If you want to view our live podcast episodes, hear about new releases, or chat with others who enjoy this podcast join one of our communities below. Join the Facebook Group Join the LinkedIn Group  

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In this episode of the Ducks Unlimited Podcast, Matt Harrison and Nathan Ratchford dive deep into the world of sporting dogs with Karl Gunzer from Purina. The discussion covers why fat and protein matter for working dogs, how to prepare your dog for hunting season, common mistakes first-time dog owners make, and cold weather precautions to keep your dog safe. Karl also shares stories from his years in field trials and offers advice for building a strong bond with your dog. This is an informative and engaging episode for anyone passionate about hunting and dog care.Listen now: www.ducks.org/DUPodcastSend feedback: DUPodcast@ducks.orgSPONSORS:Purina Pro Plan: The official performance dog food of Ducks UnlimitedWhether you're a seasoned hunter or just getting started, this episode is packed with valuable insights into the world of waterfowl hunting and conservation.Bird Dog Whiskey and Cocktails:Whether you're winding down with your best friend, or celebrating with your favorite crew, Bird Dog brings award-winning flavor to every moment. Enjoy responsibly.

Why does groundbreaking research on mind-body medicine disappear without a trace? How do emotional factors create conditions for chronic illness and autoimmune disease decades later? What happens when a Harvard study shows severe PTSD doubles ovarian cancer risk—and the medical system simply ignores it? Dr. Gabor Maté joins me to discuss the writing process behind The Myth of Normal, his 19-week New York Times bestseller bringing together decades of research on trauma, nervous system dysregulation, and how emotional factors drive physical disease. We explore why mind-body unity—understood since Socrates 2,600 years ago—remains controversial in mainstream medicine despite overwhelming scientific evidence. Gabor addresses the most damaging misconception about his work: that he blames parents and patients. Whether we're trauma-informed practitioners, healing from chronic illness, or parents navigating guilt and shame, we'll understand why this conversation about mind-body medicine is finally reaching people—even when the medical system isn't ready.   In this episode you'll learn: [01:59] The Myth of Normal Journey: How 10 years of research and 20,000 articles became a 500-page synthesis of trauma biology [04:00] Writing for Critics Made Me Sick: Why trying to convince skeptics creates the very trauma biology we're studying [06:00] Harvard's 1939 Buried Truth: Soma Weiss's lecture on emotional factors equaling physical factors—and why it's still ignored [07:42] PTSD Doubles Ovarian Cancer Risk: Harvard study the average gynecologist never read—and what it means for trauma healing [09:40] People Are Ready, Systems Aren't: Why this trauma revolution is happening at the grassroots level first [13:53] New York Times Bestseller Doesn't Equal Happiness: The personal lesson about achievement and inner state [16:00] The Biggest Misconception: Addressing the damaging claim that Gabor blames parents and patients for illness [18:00] ADHD, Genes, and Environment: Why genetic sensitivity plus stressed parents creates attention dysregulation—without blame   Main Takeaways: Mind-Body Unity Isn't New Science: Socrates recognized 2,600 years ago that separating mind from body was medicine's fundamental error, and Harvard professor Soma Weiss lectured in 1939 that emotional factors equal physical factors in disease causation and healing. This isn't cutting-edge discovery—it's forgotten wisdom the medical system repeatedly buries. Scientific Evidence Disappears in the Bermuda Triangle: Hundreds of peer-reviewed studies demonstrate trauma's biological impact on chronic illness, autoimmune disease, and cancer risk, yet research doesn't change medicine when ideology creates blind spots. A Harvard study showed severe PTSD doubles ovarian cancer risk, but the average gynecologist never reads it. Empowerment, Not Blame, Changes Lives: Understanding that stress affects multiple sclerosis relapse risk or that the environment acts on ADHD genes doesn't blame patients or parents—it empowers them. Knowledge of how trauma creates conditions for illness provides agency to address root causes rather than remaining passive recipients of symptomatic care. Mitochondrial Dysfunction Extends the Mind-Body Framework: While The Myth of Normal covers mind-body unity comprehensively, Biology of Trauma® goes deeper to subcellular levels—showing how trauma affects mitochondria, cellular energy production, and the biology underneath symptoms.   Notable Quotes: "Socrates said 2,600 years ago in ancient Greece that the problem with the doctors today is they separate the mind from the body." "Emotional factors are at least as important in the causation of disease as physiological factors, and must be at least as important in the healing." (From the 1939 Harvard lecture) "You can have the same genes and have ADHD or not have ADHD. What makes the difference is how the environment acts on those genes." "Trauma is so ubiquitous in this culture and it's so poorly understood and addressed in the healing profession." "The change will happen at the level of people, not at the system. The people will demand the system change."   Episode Takeaway: What struck me most in this conversation with Gabor is how the desperate need to convince skeptical colleagues stems from our earliest attachment patterns where authority figures' opinions determined our safety. This is why writing to prove ourselves to critics creates the very nervous system dysregulation our trauma work addresses. Mind-body unity isn't revolutionary new science—it's 2,600 years of wisdom that mainstream medicine repeatedly buries. When Harvard published research in 1939 showing emotional factors equal physical factors in disease, and recent studies demonstrate severe PTSD doubles ovarian cancer risk, the medical system's silence isn't about lack of evidence but about ideological blind spots. The revolution happening now shows people are ready for this conversation even when systems aren't. As chronic illness increases, people seek understanding of how stored trauma, nervous system dysregulation, and emotional factors create conditions for autoimmune disease, cancer, and ADHD decades later. This isn't about blaming parents or patients—it's about empowering us with agency to address root causes. External achievement doesn't heal unresolved trauma, but the gratitude when we stop trying to convince critics and instead empower people with truth makes it worthwhile. We're catching a wave we're also generating. The system will change when people demand it.   Resources/Guides: Visit biologyoftrauma.com for more resources on the Biology of Trauma® framework The Biology of Trauma book - Available now everywhere books are sold. Get your copy Foundational Journey - If you are ready to create your inner safety and shift your nervous system, join me and my team for this 6 week journey of practical somatic and mind-body inner child practices. Lay your foundation to do the deeper work safely and is the pre-requisite for becoming a Biology of Trauma® professional.  Check out Dr. Gabor Maté's book, The Myth of Normal.  Related Episodes: Episode 39: How Does Trauma Manifest in the Body with Gabor Maté Episode 66: Gabor Maté: The Biology Piece We Have Missed In Trauma & Depression (Part 1) Episode 67: Gabor Maté: Healing Trauma and Chronic Illness Through Connection (Part 2)   Your host: Dr. Aimie Apigian, double board-certified physician (Preventive/Addiction Medicine) with master's degrees in biochemistry and public health, and author of the national bestselling book "The Biology of Trauma" (foreword by Gabor Maté) that transforms our understanding of how the body experiences and holds trauma. After foster-adopting a child during medical school sparked her journey, she desperately sought for answers that would only continue as she developed chronic health issues. Through her practitioner training, podcast, YouTube channel, and international speaking, she bridges functional medicine, attachment and trauma therapy, facilitating accelerated repair of trauma's impact on the mind, body and biology. Disclaimer: By listening to this podcast, you agree not to use this podcast as medical, psychological, or mental health advice to treat any medical or psychological condition in yourself or others. This podcast is for informational and educational purposes only and does not constitute professional advice, diagnosis, or treatment. Always consult your own physician, therapist, psychiatrist, or other qualified health provider regarding any physical or mental health issues you may be experiencing.  

Dean's Chat hosts, Dr. Jensen and Richey, welcome Dr. Lindsey Hjelm from St. Cloud Minneapolis. Join us as we discuss all things podiatric medicine, including the importance of positive psychology and the importance and power of mentorship. Dr. Hjelm graduated in the top of her class with a Bachelors of Arts in Biology and a Minor in Studio Art and Religious Studies at Gustave Adolphus College in Saint Peter, Minnesota. Join us, as we discuss liberal arts education and non-traditional paths. We cover how being a student athlete helps with resiliency and grit as well as develop skills like time management. This episode is sponsored by Bako Diagnostics! She went on to complete her Doctorate of Podiatric Medical Degree with Des Moines University followed by a three year surgical residency program with Franciscan Foot and Ankle Institute in Federal Way, Washington. She completed her fellowship under the direction of Dr. Byron Hutchinson with Advanced Foot and Ankle Reconstructive Surgery Fellowship. Listen how Dr. Hjelm's career was shaped after she suffered an injury as an athlete and how having a female surgeon inspired her at a young age. We dive into how setbacks can help us become the best versions of ourselves and give us better perspectives, both as we treat patients, but also how we show up and lead others. Finally, we transition into leadership by highlighting how small the profession is and the value of relationships. We discuss the networking and connections that have shaped all of our lives and how having the courage to reach out to others who you admire can lead to opportunities you never thought may happen. Mentorship can happen organically and she discusses how mentors can be found in many places and platforms. We hope you enjoy this inspiring episode. Enjoy!

In this episode of Talk Nerdy, Cara is joined by acclaimed climatologist,  geophysicist, and University of Pennsylvania distinguished Professor, Dr. Michael Mann. They discuss his latest co-authored book, Science Under Siege: How to Fight the Five Most Powerful Forces that Threaten Our World. Follow Dr. Mann: @MichaelEMann

How can you write science-based fiction without info-dumping your research? How can you use AI tools in a creative way, while still focusing on a human-first approach? Why is adapting to the fast pace of change so difficult and how can we make the most of this time? Jamie Metzl talks about Superconvergence and more. In the intro, How to avoid author scams [Written Word Media]; Spotify vs Audible audiobook strategy [The New Publishing Standard]; Thoughts on Author Nation and why constraints are important in your author life [Self-Publishing with ALLi]; Alchemical History And Beautiful Architecture: Prague with Lisa M Lilly on my Books and Travel Podcast. Today's show is sponsored by Draft2Digital, self-publishing with support, where you can get free formatting, free distribution to multiple stores, and a host of other benefits. Just go to www.draft2digital.com to get started. This show is also supported by my Patrons. Join my Community at Patreon.com/thecreativepenn Jamie Metzl is a technology futurist, professional speaker, entrepreneur, and the author of sci-fi thrillers and futurist nonfiction books, including the revised and updated edition of Superconvergence: How the Genetics, Biotech, and AI Revolutions Will Transform Our Lives, Work, and World. You can listen above or on your favorite podcast app or read the notes and links below. Here are the highlights and the full transcript is below. Show Notes How personal history shaped Jamie's fiction writing Writing science-based fiction without info-dumping The super convergence of three revolutions (genetics, biotech, AI) and why we need to understand them holistically Using fiction to explore the human side of genetic engineering, life extension, and robotics Collaborating with GPT-5 as a named co-author How to be a first-rate human rather than a second-rate machine You can find Jamie at JamieMetzl.com. Transcript of interview with Jamie Metzl Jo: Jamie Metzl is a technology futurist, professional speaker, entrepreneur, and the author of sci-fi thrillers and futurist nonfiction books, including the revised and updated edition of Superconvergence: How the Genetics, Biotech, and AI Revolutions Will Transform Our Lives, Work, and World. So welcome, Jamie. Jamie: Thank you so much, Jo. Very happy to be here with you. Jo: There is so much we could talk about, but let's start with you telling us a bit more about you and how you got into writing. From History PhD to First Novel Jamie: Well, I think like a lot of writers, I didn't know I was a writer. I was just a kid who loved writing. Actually, just last week I was going through a bunch of boxes from my parents' house and I found my autobiography, which I wrote when I was nine years old. So I've been writing my whole life and loving it. It was always something that was very important to me. When I finished my DPhil, my PhD at Oxford, and my dissertation came out, it just got scooped up by Macmillan in like two minutes. And I thought, “God, that was easy.” That got me started thinking about writing books. I wanted to write a novel based on the same historical period – my PhD was in Southeast Asian history – and I wanted to write a historical novel set in the same period as my dissertation, because I felt like the dissertation had missed the human element of the story I was telling, which was related to the Cambodian genocide and its aftermath. So I wrote what became my first novel, and I thought, “Wow, now I'm a writer.” I thought, “All right, I've already published one book. I'm gonna get this other book out into the world.” And then I ran into the brick wall of: it's really hard to be a writer. It's almost easier to write something than to get it published. I had to learn a ton, and it took nine years from when I started writing that first novel, The Depths of the Sea, to when it finally came out. But it was such a positive experience, especially to have something so personal to me as that story. I'd lived in Cambodia for two years, I'd worked on the Thai-Cambodian border, and I'm the child of a Holocaust survivor. So there was a whole lot that was very emotional for me. That set a pattern for the rest of my life as a writer, at least where, in my nonfiction books, I'm thinking about whatever the issues are that are most important to me. Whether it was that historical book, which was my first book, or Hacking Darwin on the future of human genetic engineering, which was my last book, or Superconvergence, which, as you mentioned in the intro, is my current book. But in every one of those stories, the human element is so deep and so profound. You can get at some of that in nonfiction, but I've also loved exploring those issues in deeper ways in my fiction. So in my more recent novels, Genesis Code and Eternal Sonata, I've looked at the human side of the story of genetic engineering and human life extension. And now my agent has just submitted my new novel, Virtuoso, about the intersection of AI, robotics, and classical music. With all of this, who knows what's the real difference between fiction and nonfiction? We're all humans trying to figure things out on many different levels. Shifting from History to Future Tech Jo: I knew that you were a polymath, someone who's interested in so many things, but the music angle with robotics and AI is fascinating. I do just want to ask you, because I was also at Oxford – what college were you at? Jamie: I was in St. Antony's. Jo: I was at Mansfield, so we were in that slightly smaller, less famous college group, if people don't know. Jamie: You know, but we're small but proud. Jo: Exactly. That's fantastic. You mentioned that you were on the historical side of things at the beginning and now you've moved into technology and also science, because this book Superconvergence has a lot of science. So how did you go from history and the past into science and the future? Biology and Seeing the Future Coming Jamie: It's a great question. I'll start at the end and then back up. A few years ago I was speaking at Lawrence Livermore National Laboratory, which is one of the big scientific labs here in the United States. I was a guest of the director and I was speaking to their 300 top scientists. I said to them, “I'm here to speak with you about the future of biology at the invitation of your director, and I'm really excited. But if you hear something wrong, please raise your hand and let me know, because I'm entirely self-taught. The last biology course I took was in 11th grade of high school in Kansas City.” Of course I wouldn't say that if I didn't have a lot of confidence in my process. But in many ways I'm self-taught in the sciences. As you know, Jo, and as all of your listeners know, the foundation of everything is curiosity and then a disciplined process for learning. Even our greatest super-specialists in the world now – whatever their background – the world is changing so fast that if anyone says, “Oh, I have a PhD in physics/chemistry/biology from 30 years ago,” the exact topic they learned 30 years ago is less significant than their process for continuous learning. More specifically, in the 1990s I was working on the National Security Council for President Clinton, which is the president's foreign policy staff. My then boss and now close friend, Richard Clarke – who became famous as the guy who had tragically predicted 9/11 – used to say that the key to efficacy in Washington and in life is to try to solve problems that other people can't see. For me, almost 30 years ago, I felt to my bones that this intersection of what we now call AI and the nascent genetics revolution and the nascent biotechnology revolution was going to have profound implications for humanity. So I just started obsessively educating myself. When I was ready, I started writing obscure national security articles. Those got a decent amount of attention, so I was invited to testify before the United States Congress. I was speaking out a lot, saying, “Hey, this is a really important story. A lot of people are missing it. Here are the things we should be thinking about for the future.” I wasn't getting the kind of traction that I wanted. I mentioned before that my first book had been this dry Oxford PhD dissertation, and that had led to my first novel. So I thought, why don't I try the same approach again – writing novels to tell this story about the genetics, biotech, and what later became known popularly as the AI revolution? That led to my two near-term sci-fi novels, Genesis Code and Eternal Sonata. On my book tours for those novels, when I explained the underlying science to people in my way, as someone who taught myself, I could see in their eyes that they were recognizing not just that something big was happening, but that they could understand it and feel like they were part of that story. That's what led me to write Hacking Darwin, as I mentioned. That book really unlocked a lot of things. I had essentially predicted the CRISPR babies that were born in China before it happened – down to the specific gene I thought would be targeted, which in fact was the case. After that book was published, Dr. Tedros, the Director-General of the World Health Organization, invited me to join the WHO Expert Advisory Committee on Human Genome Editing, which I did. It was a really great experience and got me thinking a lot about the upside of this revolution and the downside. The Birth of Superconvergence Jamie: I get a lot of wonderful invitations to speak, and I have two basic rules for speaking: Never use notes. Never ever. Never stand behind a podium. Never ever. Because of that, when I speak, my talks tend to migrate. I'd be speaking with people about the genetics revolution as it applied to humans, and I'd say, “Well, this is just a little piece of a much bigger story.” The bigger story is that after nearly four billion years of life on Earth, our one species has the increasing ability to engineer novel intelligence and re-engineer life. The big question for us, and frankly for the world, is whether we're going to be able to use that almost godlike superpower wisely. As that idea got bigger and bigger, it became this inevitable force. You write so many books, Jo, that I think it's second nature for you. Every time I finish a book, I think, “Wow, that was really hard. I'm never doing that again.” And then the books creep up on you. They call to you. At some point you say, “All right, now I'm going to do it.” So that was my current book, Superconvergence. Like everything, every journey you take a step, and that step inspires another step and another. That's why writing and living creatively is such a wonderfully exciting thing – there's always more to learn and always great opportunities to push ourselves in new ways. Balancing Deep Research with Good Storytelling Jo: Yeah, absolutely. I love that you've followed your curiosity and then done this disciplined process for learning. I completely understand that. But one of the big issues with people like us who love the research – and having read your Superconvergence, I know how deeply you go into this and how deeply you care that it's correct – is that with fiction, one of the big problems with too much research is the danger of brain-dumping. Readers go to fiction for escapism. They want the interesting side of it, but they want a story first. What are your tips for authors who might feel like, “Where's the line between putting in my research so that it's interesting for readers, but not going too far and turning it into a textbook?” How do you find that balance? Jamie: It's such a great question. I live in New York now, but I used to live in Washington when I was working for the U.S. government, and there were a number of people I served with who later wrote novels. Some of those novels felt like policy memos with a few sex scenes – and that's not what to do. To write something that's informed by science or really by anything, everything needs to be subservient to the story and the characters. The question is: what is the essential piece of information that can convey something that's both important to your story and your character development, and is also an accurate representation of the world as you want it to be? I certainly write novels that are set in the future – although some of them were a future that's now already happened because I wrote them a long time ago. You can make stuff up, but as an author you have to decide what your connection to existing science and existing technology and the existing world is going to be. I come at it from two angles. One: I read a huge number of scientific papers and think, “What does this mean for now, and if you extrapolate into the future, where might that go?” Two: I think about how to condense things. We've all read books where you're humming along because people read fiction for story and emotional connection, and then you hit a bit like: “I sat down in front of the president, and the president said, ‘Tell me what I need to know about the nuclear threat.'” And then it's like: insert memo. That's a deal-killer. It's like all things – how do you have a meaningful relationship with another person? It's not by just telling them your story. Even when you're telling them something about you, you need to be imagining yourself sitting in their shoes, hearing you. These are very different disciplines, fiction and nonfiction. But for the speculative nonfiction I write – “here's where things are now, and here's where the world is heading” – there's a lot of imagination that goes into that too. It feels in many ways like we're living in a sci-fi world because the rate of technological change has been accelerating continuously, certainly for the last 12,000 years since the dawn of agriculture. It's a balance. For me, I feel like I'm a better fiction writer because I write nonfiction, and I'm a better nonfiction writer because I write fiction. When I'm writing nonfiction, I don't want it to be boring either – I want people to feel like there's a story and characters and that they can feel themselves inside that story. Jo: Yeah, definitely. I think having some distance helps as well. If you're really deep into your topics, as you are, you have to leave that manuscript a little bit so you can go back with the eyes of the reader as opposed to your eyes as the expert. Then you can get their experience, which is great. Looking Beyond Author-Focused AI Fears Jo: I want to come to your technical knowledge, because AI is a big thing in the author and creative community, like everywhere else. One of the issues is that creators are focusing on just this tiny part of the impact of AI, and there's a much bigger picture. For example, in 2024, Demis Hassabis from Google DeepMind and his collaborative partner John Jumper won the Nobel Prize for Chemistry with AlphaFold. It feels to me like there's this massive world of what's happening with AI in health, climate, and other areas, and yet we are so focused on a lot of the negative stuff. Maybe you could give us a couple of things about what there is to be excited and optimistic about in terms of AI-powered science? Jamie: Sure. I'm so excited about all of the new opportunities that AI creates. But I also think there's a reason why evolution has preserved this very human feeling of anxiety: because there are real dangers. Anybody who's Pollyanna-ish and says, “Oh, the AI story is inevitably positive,” I'd be distrustful. And anyone who says, “We're absolutely doomed, this is the end of humanity,” I'd also be distrustful. So let me tell you the positives and the negatives, and maybe some thoughts about how we navigate toward the former and away from the latter. AI as the New Electricity Jamie: When people think of AI right now, they're thinking very narrowly about these AI tools and ChatGPT. But we don't think of electricity that way. Nobody says, “I know electricity – electricity is what happens at the power station.” We've internalised the idea that electricity is woven into not just our communication systems or our houses, but into our clothes, our glasses – it's woven into everything and has super-empowered almost everything in our modern lives. That's what AI is. In Superconvergence, the majority of the book is about positive opportunities: In healthcare, moving from generalised healthcare based on population averages to personalised or precision healthcare based on a molecular understanding of each person's individual biology. As we build these massive datasets like the UK Biobank, we can take a next jump toward predictive and preventive healthcare, where we're able to address health issues far earlier in the process, when interventions can be far more benign. I'm really excited about that, not to mention the incredible new kinds of treatments – gene therapies, or pharmaceuticals based on genetics and systems-biology analyses of patients. Then there's agriculture. Over the last hundred years, because of the technologies of the Green Revolution and synthetic fertilisers, we've had an incredible increase in agricultural productivity. That's what's allowed us to quadruple the global population. But if we just continue agriculture as it is, as we get towards ten billion wealthier, more empowered people wanting to eat like we eat, we're going to have to wipe out all the wild spaces on Earth to feed them. These technologies help provide different paths toward increasing agricultural productivity with fewer inputs of land, water, fertiliser, insecticides, and pesticides. That's really positive. I could go on and on about these positives – and I do – but there are very real negatives. I was a member of the WHO Expert Advisory Committee on Human Genome Editing after the first CRISPR babies were very unethically created in China. I'm extremely aware that these same capabilities have potentially incredible upsides and very real downsides. That's the same as every technology in the past, but this is happening so quickly that it's triggering a lot of anxieties. Governance, Responsibility, and Why Everyone Has a Role Jamie: The question now is: how do we optimise the benefits and minimise the harms? The short, unsexy word for that is governance. Governance is not just what governments do; it's what all of us do. That's why I try to write books, both fiction and nonfiction, to bring people into this story. If people “other” this story – if they say, “There's a technology revolution, it has nothing to do with me, I'm going to keep my head down” – I think that's dangerous. The way we're going to handle this as responsibly as possible is if everybody says, “I have some role. Maybe it's small, maybe it's big. The first step is I need to educate myself. Then I need to have conversations with people around me. I need to express my desires, wishes, and thoughts – with political leaders, organisations I'm part of, businesses.” That has to happen at every level. You're in the UK – you know the anti-slavery movement started with a handful of people in Cambridge and grew into a global movement. I really believe in the power of ideas, but ideas don't spread on their own. These are very human networks, and that's why writing, speaking, communicating – probably for every single person listening to this podcast – is so important. Jo: Mm, yeah. Fiction Like AI 2041 and Thinking Through the Issues Jo: Have you read AI 2041 by Kai-Fu Lee and Chen Qiufan? Jamie: No. I heard a bunch of their interviews when the book came out, but I haven't read it. Jo: I think that's another good one because it's fiction – a whole load of short stories. It came out a few years ago now, but the issues they cover in the stories, about different people in different countries – I remember one about deepfakes – make you think more about the topics and help you figure out where you stand. I think that's the issue right now: it's so complex, there are so many things. I'm generally positive about AI, but of course I don't want autonomous drone weapons, you know? The Messy Reality of “Bad” Technologies Jamie: Can I ask you about that? Because this is why it's so complicated. Like you, I think nobody wants autonomous killer drones anywhere in the world. But if you right now were the defence minister of Ukraine, and your children are being kidnapped, your country is being destroyed, you're fighting for your survival, you're getting attacked every night – and you're getting attacked by the Russians, who are investing more and more in autonomous killer robots – you kind of have two choices. You can say, “I'm going to surrender,” or, “I'm going to use what technology I have available to defend myself, and hopefully fight to either victory or some kind of stand-off.” That's what our societies did with nuclear weapons. Maybe not every American recognises that Churchill gave Britain's nuclear secrets to America as a way of greasing the wheels of the Anglo-American alliance during the Second World War – but that was our programme: we couldn't afford to lose that war, and we couldn't afford to let the Nazis get nuclear weapons before we did. So there's the abstract feeling of, “I'm against all war in the abstract. I'm against autonomous killer robots in the abstract.” But if I were the defence minister of Ukraine, I would say, “What will it take for us to build the weapons we can use to defend ourselves?” That's why all this stuff gets so complicated. And frankly, it's why the relationship between fiction and nonfiction is so important. If every novel had a situation where every character said, “Oh, I know exactly the right answer,” and then they just did the right answer and it was obviously right, it wouldn't make for great fiction. We're dealing with really complex humans. We have conflicting impulses. We're not perfect. Maybe there are no perfect answers – but how do we strive toward better rather than worse? That's the question. Jo: Absolutely. I don't want to get too political on things. How AI Is Changing the Writing Life Jo: Let's come back to authors. In terms of the creative process, the writing process, the research process, and the business of being an author – what are some of the ways that you already use AI tools, and some of the ways, given your futurist brain, that you think things are going to change for us? Jamie: Great question. I'll start with a little middle piece. I found you, Jo, through GPT-5. I asked ChatGPT, “I'm coming out with this book and I want to connect with podcasters who are a little different from the ones I've done in the past. I've been a guest on Joe Rogan twice and some of the bigger podcasts. Make me a list of really interesting people I can have great conversations with.” That's how I found you. So this is one reward of that process. Let me say that in the last year I've worked on three books, and I'll explain how my relationship with AI has changed over those books. Cleaning Up Citations (and Getting Burned) Jamie: First is the highly revised paperback edition of Superconvergence. When the hardback came out, I had – I don't normally work with research assistants because I like to dig into everything myself – but the one thing I do use a research assistant for is that I can't be bothered, when I'm writing something, to do the full Chicago-style footnote if I'm already referencing an academic paper. So I'd just put the URL as the footnote and then hire a research assistant and say, “Go to this URL and change it into a Chicago-style citation. That's it.” Unfortunately, my research assistant on the hardback used early-days ChatGPT for that work. He did the whole thing, came back, everything looked perfect. I said, “Wow, amazing job.” It was only later, as I was going through them, that I realised something like 50% of them were invented footnotes. It was very painful to go back and fix, and it took ten times more time. With the paperback edition, I didn't use AI that much, but I did say things like, “Here's all the information – generate a Chicago-style citation.” That was better. I noticed there were a few things where I stopped using the thesaurus function on Microsoft Word because I'd just put the whole paragraph into the AI and say, “Give me ten other options for this one word,” and it would be like a contextual thesaurus. That was pretty good. Talking to a Robot Pianist Character Jamie: Then, for my new novel Virtuoso, I was writing a character who is a futurist robot that plays the piano very beautifully – not just humanly, but almost finding new things in the music we've written and composing music that resonates with us. I described the actions of that robot in the novel, but I didn't describe the inner workings of the robot's mind. In thinking about that character, I realised I was the first science-fiction writer in history who could interrogate a machine about what it was “thinking” in a particular context. I had the most beautiful conversations with ChatGPT, where I would give scenarios and ask, “What are you thinking? What are you feeling in this context?” It was all background for that character, but it was truly profound. Co-Authoring The AI Ten Commandments with GPT-5 Jamie: Third, I have another book coming out in May in the United States. I gave a talk this summer at the Chautauqua Institution in upstate New York about AI and spirituality. I talked about the history of our human relationship with our technology, about how all our religious and spiritual traditions have deep technological underpinnings – certainly our Abrahamic religions are deeply connected to farming, and Protestantism to the printing press. Then I had a section about the role of AI in generating moral codes that would resonate with humans. Everybody went nuts for this talk, and I thought, “I think I'm going to write a book.” I decided to write it differently, with GPT-5 as my named co-author. The first thing I did was outline the entire book based on the talk, which I'd already spent a huge amount of time thinking about and organising. Then I did a full outline of the arguments and structures. Then I trained GPT-5 on my writing style. The way I did it – which I fully describe in the introduction to the book – was that I'd handle all the framing: the full introduction, the argument, the structure. But if there was a section where, for a few paragraphs, I was summarising a huge field of data, even something I knew well, I'd give GPT-5 the intro sentence and say, “In my writing style, prepare four paragraphs on this.” For example, I might write: “AI has the potential to see us humans like we humans see ant colonies.” Then I'd say, “Give me four paragraphs on the relationship between the individual and the collective in ant colonies.” I could have written those four paragraphs myself, but it would've taken a month to read the life's work of E.O. Wilson and then write them. GPT-5 wrote them in seconds or minutes, in its thinking mode. I'd then say, “It's not quite right – change this, change that,” and we'd go back and forth three or four times. Then I'd edit the whole thing and put it into the text. So this book that I could have written on my own in a year, I wrote a first draft of with GPT-5 as my named co-author in two days. The whole project will take about six months from start to finish, and I'm having massive human editing – multiple edits from me, plus a professional editor. It's not a magic AI button. But I feel strongly about listing GPT-5 as a co-author because I've written it differently than previous books. I'm a huge believer in the old-fashioned lone author struggling and suffering – that's in my novels, and in Virtuoso I explore that. But other forms are going to emerge, just like video games are a creative, artistic form deeply connected to technology. The novel hasn't been around forever – the current format is only a few centuries old – and forms are always changing. There are real opportunities for authors, and there will be so much crap flooding the market because everybody can write something and put it up on Amazon. But I think there will be a very special place for thoughtful human authors who have an idea of what humans do at our best, and who translate that into content other humans can enjoy. Traditional vs Indie: Why This Book Will Be Self-Published Jo: I'm interested – you mentioned that it's your named co-author. Is this book going through a traditional publisher, and what do they think about that? Or are you going to publish it yourself? Jamie: It's such a smart question. What I found quickly is that when you get to be an author later in your career, you have all the infrastructure – a track record, a fantastic agent, all of that. But there were two things that were really important to me here: I wanted to get this book out really fast – six months instead of a year and a half. It was essential to me to have GPT-5 listed as my co-author, because if it were just my name, I feel like it would be dishonest. Readers who are used to reading my books – I didn't want to present something different than what it was. I spoke with my agent, who I absolutely love, and she said that for this particular project it was going to be really hard in traditional publishing. So I did a huge amount of research, because I'd never done anything in the self-publishing world before. I looked at different models. There was one hybrid model that's basically the same as traditional, but you pay for the things the publisher would normally pay for. I ended up not doing that. Instead, I decided on a self-publishing route where I disaggregated the publishing process. I found three teams: one for producing the book, one for getting the book out into the world, and a smaller one for the audiobook. I still believe in traditional publishing – there's a lot of wonderful human value-add. But some works just don't lend themselves to traditional publishing. For this book, which is called The AI Ten Commandments, that's the path I've chosen. Jo: And when's that out? I think people will be interested. Jamie: April 26th. Those of us used to traditional publishing think, “I've finished the book, sold the proposal, it'll be out any day now,” and then it can be a year and a half. It's frustrating. With this, the process can be much faster because it's possible to control more of the variables. But the key – as I was saying – is to make sure it's as good a book as everything else you've written. It's great to speed up, but you don't want to compromise on quality. The Coming Flood of Excellent AI-Generated Work Jo: Yeah, absolutely. We're almost out of time, but I want to come back to your “flood of crap” and the “AI slop” idea that's going around. Because you are working with GPT-5 – and I do as well, and I work with Claude and Gemini – and right now there are still issues. Like you said about referencing, there are still hallucinations, though fewer. But fast-forward two, five years: it's not a flood of crap. It's a flood of excellent. It's a flood of stuff that's better than us. Jamie: We're humans. It's better than us in certain ways. If you have farm machinery, it's better than us at certain aspects of farming. I'm a true humanist. I think there will be lots of things machines do better than us, but there will be tons of things we do better than them. There's a reason humans still care about chess, even though machines can beat humans at chess. Some people are saying things I fully disagree with, like this concept of AGI – artificial general intelligence – where machines do everything better than humans. I've summarised my position in seven letters: “AGI is BS.” The only way you can believe in AGI in that sense is if your concept of what a human is and what a human mind is is so narrow that you think it's just a narrow range of analytical skills. We are so much more than that. Humans represent almost four billion years of embodied evolution. There's so much about ourselves that we don't know. As incredible as these machines are and will become, there will always be wonderful things humans can do that are different from machines. What I always tell people is: whatever you're doing, don't be a second-rate machine. Be a first-rate human. If you're doing something and a machine is doing that thing much better than you, then shift to something where your unique capacities as a human give you the opportunity to do something better. So yes, I totally agree that the quality of AI-generated stuff will get better. But I think the most creative and successful humans will be the ones who say, “I recognise that this is creating new opportunities, and I'm going to insert my core humanity to do something magical and new.” People are “othering” these technologies, but the technologies themselves are magnificent human-generated artefacts. They're not alien UFOs that landed here. It's a scary moment for creatives, no doubt, because there are things all of us did in the past that machines can now do really well. But this is the moment where the most creative people ask themselves, “What does it mean for me to be a great human?” The pat answers won't apply. In my Virtuoso novel I explore that a lot. The idea that “machines don't do creativity” – they will do incredible creativity; it just won't be exactly human creativity. We will be potentially huge beneficiaries of these capabilities, but we really have to believe in and invest in the magic of our core humanity. Where to Find Jamie and His Books Jo: Brilliant. So where can people find you and your books online? Jamie: Thank you so much for asking. My website is jamiemetzl.com – and my books are available everywhere. Jo: Fantastic. Thanks so much for your time, Jamie. That was great. Jamie: Thank you, Joanna.The post Writing The Future, And Being More Human In An Age of AI With Jamie Metzl first appeared on The Creative Penn.

The International Olympic Committee is poised to ban biological men from women's sports, a decisive break from trans ideology and a win for fairness, safety, and reality. When major institutions finally admit biology matters, the left's entire narrative begins to crumble. This is what a turning point looks like.Learn more at https://www.standingforfreedom.com/Facebook: https://www.facebook.com/freedomcenterlu/ Twitter: https://x.com/freedomcenterluInstagram: https://www.instagram.com/freedomcenterlu/

Full Shownotes: https://bengreenfieldlife.com/rootcause Morley Robbins is the creator and founder of The Root Cause Protocol and the Magnesium Advocacy Group. Morley received his BA in Biology from Denison University in Ohio and holds an MBA from George Washington University in healthcare administration. Morley has trained in wellness coaching, nutritional counselling, and functional diagnostic nutrition. He is also known as the Magnesium Man due to his extensive research into and understanding of magnesium’s role in the body. Morley’s research saw him deciphering the intricate relationship between magnesium, iron, copper, and calcium as a way to free ourselves from illness and dis-ease. As a certified health coach with an expertise in Hair Tissue Mineral Analysis (HTMA), Morley has performed thousands of RCP one-on-one consultations, helping people feel better by getting to the root cause of their symptoms. The Root Cause Protocol (RCP) we discuss in this podcast was developed by Morley, who transformed a career in the mainstream medical industry into a quest to learn the fundamental components of a healthy metabolism. The RCP claims to work by restoring balance to the key minerals – magnesium, copper and iron – that must work together in order to optimize energy and increase vitality. Now, the RCP is in Morley‘s new book “Cure Your Fatigue” This book is designed for those seeking the truth in human metabolism and those wanting to take back control of their health. It is one part textbook and one part user's guide based on a decade of research and client experience Episode Sponsors: Truvaga: Balance your nervous system naturally with Truvaga's vagus nerve stimulator. Visit Truvaga.com/Greenfield and use code GREENFIELD30 to save $30 off any Truvaga device. Calm your mind, focus better, and recover faster in just two minutes. Pique: Pique Teas is where plants and science intersect to produce teas and supplements of unrivaled efficacy, purity, and convenience. Go to Piquelife.com/Ben to get 20% off for life, plus a free starter kit with a rechargeable frother and glass beaker to elevate your ritual. LeelaQ: Not only do LeelaQ’s products neutralize EMFs, increase ATP production, optimize HRV, and improve blood flow, but they've been third-party proven to do so in placebo-controlled double-blind studies. Visit leelaq.com and use code BEN10 for 10% off. Timeline Nutrition: Give your cells new life with high-performance products powered by Mitopure, Timeline's powerful ingredient that unlocks a precise dose of the rare Urolithin A molecule and promotes healthy aging. Go to shop.timeline.com/BEN and use code BEN to get 20% off your order. ZBiotics Pre-Alcohol Probiotic: The world's first genetically engineered probiotic that helps break down the toxic byproduct of alcohol, Zbiotics Pre-Alcohol allows you to enjoy your night out and feel great the next day. Order with the confidence of a 100% money-back guarantee and 15% off your first order at zbiotics.com/BEN15. BON CHARGE: BON CHARGE is a holistic wellness brand with a wide range of products that naturally address the issues of modern life. Their products can help you sleep better, perform better, recover faster, balance hormones, reduce inflammation, and so much more. Go to boncharge.com/GREENFIELD to save 25% off for a limited time.See omnystudio.com/listener for privacy information.

Researchers believe it will be possible in the near future to build organisms from molecules with reversed structures. But a recent multi-disciplinary report suggest that creating such "mirror life" could lead to the end of all known life on earth. Jeff and Anthony discuss the report, and what it means for synthetic biology.LInk to the story: https://news.stanford.edu/stories/2024/12/potential-risks-of-mirror-lifeSupport the show and get bonus episodes, videos, Discord community access and more! http://patreon.com/wehaveconcernsJeff on Blue Sky: https://bsky.app/profile/jeffcannata.bsky.socialAnthony on Blue Sky: https://bsky.app/profile/acarboni.bsky.social

This unique episode is all about food. Guest Jennifer Chandler, chef and author, joins Chris Jennings and Dr. Mike Brasher for a Thanksgiving discussion that is centered around the theme of “Best Thing I Ever Ate at Duck Camp.” The trio talk about their personal Thanksgiving plans, the waterfowling aspect of the holiday season, and also break down multiple clips from past guests talking about their favorite duck camp meals. This engaging conversation will leave you thinking about your favorite things to eat at duck camp, and hungry for a Thanksgiving feast.Happy Thanksgiving!Listen now: www.ducks.org/DUPodcastSend feedback: DUPodcast@ducks.orgSPONSORS:Purina Pro Plan: The official performance dog food of Ducks UnlimitedWhether you're a seasoned hunter or just getting started, this episode is packed with valuable insights into the world of waterfowl hunting and conservation.Bird Dog Whiskey and Cocktails:Whether you're winding down with your best friend, or celebrating with your favorite crew, Bird Dog brings award-winning flavor to every moment. Enjoy responsibly.

Bruce Lipton drops a truth bomb that will shake your entire understanding of reality: you are not living your life, you're living a program installed by your parents before you could even tie your shoes. For the first 40-plus years of his life, Bruce struggled with relationships, depression, and feeling like a victim until he discovered the science behind why we stay stuck. His research in cellular biology revealed that our cells don't respond to genes, they respond to consciousness, and that the broadcast we're receiving shapes everything from our bank accounts to our health to whether we can sustain love. He shares the exact moment he broke free from decades of self-sabotage and depression, the scientific proof that thoughts are not contained in your head, and why 80% of people fail a simple muscle test for self-love. This conversation will either wake you up or confirm you've chosen to stay asleep.Bruce's books:The Biology of BeliefSpontaneous EvolutionThe Honeymoon EffectIn this episode you will:Discover why 95% of your daily behavior comes from programs installed before age seven and how those programs sabotage everything you consciously wantUnderstand the scientific mechanism proving you are not your body but a spiritual broadcast that can never die, eliminating the fear that controls most human decisionsMaster the difference between thinking positive thoughts and actually reprogramming your subconscious so you stop working against yourself 24/7Learn why 60% of your downloaded programs are disempowering and how the victim mentality you carry was never yours to begin withBreak free from the illusion that genes control your health and wealth when the real power lies in changing the field your consciousness broadcasts into realityFor more information go to https://lewishowes.com/1853For more Greatness text PODCAST to +1 (614) 350-3960More SOG episodes we think you'll love:Gabor Maté – greatness.lnk.to/1849SCDr. Marc Brackett  – greatness.lnk.to/1843SCDr. Joe Dispenza – greatness.lnk.to/1809SC Get more from Lewis! Get my New York Times Bestselling book, Make Money Easy!Get The Greatness Mindset audiobook on SpotifyText Lewis AIYouTubeInstagramWebsiteTiktokFacebookX Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Listen now: www.ducks.org/DUPodcastSend feedback: DUPodcast@ducks.orgSPONSORS:Purina Pro Plan: The official performance dog food of Ducks UnlimitedWhether you're a seasoned hunter or just getting started, this episode is packed with valuable insights into the world of waterfowl hunting and conservation.Bird Dog Whiskey and Cocktails:Whether you're winding down with your best friend, or celebrating with your favorite crew, Bird Dog brings award-winning flavor to every moment. Enjoy responsibly.

Some animals have a very different relationship to aging than we do: They don't get cancer, they never go through menopause, and they live absurdly long lives. For instance, one bat species can live for more than 40 years, which may not sound like very long but that's about nine times longer than expected based on its size. For comparison, if we aged on that scale, we'd live for hundreds of years. These bats aren't the only animal super-agers—there's a whole menagerie of them.So what's their secret? And can we learn anything from them that might help us live longer, healthier lives? Host Flora Lichtman talks with longevity researchers Vera Gorbunova and Juan Manuel Vazquez about what animals are teaching us.Guests:Dr. Vera Gorbunova is a biologist and professor at the University of Rochester, and a co-director of the Rochester Aging Research Center.Dr. Juan Manuel Vazquez is a biologist and assistant professor at Pennsylvania State University studying the evolution of aging.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

Proteins are crucial for life. They're made of amino acids that “fold” into millions of different shapes. And depending on their structure, they do radically different things in our cells. For a long time, predicting those shapes for research was considered a grand biological challenge.But in 2020, Google's AI lab DeepMind released Alphafold, a tool that was able to accurately predict many of the structures necessary for understanding biological mechanisms in a matter of minutes. In 2024, the Alphafold team was awarded a Nobel Prize in chemistry for the advance.Five years later after its release, Host Ira Flatow checks in on the state of that tech and how it's being used in health research with John Jumper, one of the lead scientists responsible for developing Alphafold.Guest: John Jumper, scientist at Google Deepmind and co-recipient of the 2024 Nobel Prize in chemistry.Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.